| P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
|---|
| 8.002e-48 | -108.44 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | 2173 | 418 | 17385 | 1698 |
ARHGAP26,FAM171B,PLBD2,PPP4R4,PAGE1,LGR4,AASS,RECK,LSM11,PPFIBP2,NPM1,CADM2,KIAA1217,SNX9,DACH2,NOS1AP,PCDH7,EPDR1,TGFBR3,ZFYVE28,DNAH6,SLC16A2,PPFIA2,RAP2A,ATRNL1,PPP2R2B,VWA5A,CPE,EML6,DCDC1,ACVR1C,DCC,CAP2,KLHL4,DSTN,KCND3,GPC6,GNAI1,AHRR,WIPF3,ENPP6,ATP7B,CCBE1,RASGRF2,BDH2,SEMA3C,INPP5F,TANC2,UNC5B,TMEFF2,EFNB2,PTPRD,TBC1D1,CYP2J2,ST6GAL1,OLAH,OPHN1,TJP1,LRRC49,SLC1A3,DYNC1I1,SLC7A11,NOVA2,FAM189A1,MYC,RUNDC3B,PRKG1,SRGAP1,GRIP1,CPXM2,MPDZ,TOX,CADPS2,TSPAN12,ALPK1,FIGN,FAM155A,AGL,GLIS1,PRR16,TSPAN9,COL9A2,FMNL2,LRP12,HMGCR,PTCH2,KCNQ3,TBC1D8B,MYO10,VLDLR,ARID5B,RAPGEF4,RYR2,TTYH2,CALCRL,HIP1,PLS1,AIG1,ST6GALNAC3,CCDC85A,ZBBX,PLCB1,DHX32,CACHD1,XKR9,PLEKHH2,SH3GL2,PMEPA1,ADAMTS3,PELI2,C1orf21,LRRIQ3,DHCR7,CDH2,PLA2G4A,EPHA3,DNM3,TCTN2,RASAL2,ZNF311,MSR1,PLXNA2,IL13RA1,SPATS2L,COLEC10,SLC19A2,TXNRD3,CDS1,COL25A1,NBEA,DNAH5,MYT1,KCNB2,GAB2,TRDMT1,COL6A2,NECAB1,PDK1,KCNH5,SHANK2,ADCY1,NLGN4X,SATB2,TTC28,ASPH,TBC1D16,ZNF618,SNCA,IQCK,ARHGAP21,GYPC,TDO2,PEMT,WWTR1,LAMB1,INPP4B,ZNF704,KLF5,GRB10,CTTNBP2,NR3C2,COBL,STON2,HACE1,ANO10,MYO1D,CCDC148,ROBO2,GLIPR1L1,ATP9A,EPS8,UBAC2,CCNJL,NKAIN2,PSD3,SLC12A6,CREB5,NDFIP2,TPD52L1,COL27A1,NEDD4,LRRC55,GHR,DYNC2H1,MYO6,C15orf41,PARP9,TRPM4,BCL7A,SLC40A1,VAV3,ARHGEF28,CLYBL,PTPN13,ZDHHC15,RASA3,GUCY1A2,SNTB1,SKAP1,GPR137C,HEG1,PTPRC,ID3,PLOD2,PLXDC2,GNAO1,NEK11,HK1,DCBLD1,CRISPLD1,OCLN,BTRC,EXPH5,PHACTR3,CACNG3,HEBP1,ITPR2,FAM13A,NOVA1,DNER,HMCN1,FSTL5,CEP85L,RTN1,SIPA1L2,SEC16B,KCNN2,LRRC6,AKAP7,ABI3BP,SLC10A7,ANKFN1,MPPED2,COL19A1,LIN7A,TRPC1,SLC2A12,TLN2,MYRIP,FANK1,SLIT2,PGBD5,GPM6A,SKAP2,ABCC4,ANK2,JPH1,ROR1,SESN1,SERGEF,EML1,TRIM9,TMEM132B,TCF7L1,KLF12,ITGBL1,NCAM2,MAP2,TECPR2,PPARGC1A,MAGI2,MLLT3,FRMD5,HS6ST3,RRAGD,UST,BCL11B,STXBP5L,FN1,BVES,UBASH3B,ZCCHC24,STXBP6,SETBP1,GALNT13,CHSY1,FAM81A,SATB1,FHOD3,HSPA12B,RNF141,KIAA1958,IGF1R,BCHE,FRAS1,PDE10A,EBF4,FAM107B,LRP6,LIMCH1,SLCO4C1,FBXL2,DPYSL5,CHSY3,CDH26,UNC5C,PCDH10,SDC3,STRADB,SDK1,B4GALNT3,KHDRBS2,NEGR1,GRIK4,KIAA0355,NCR3LG1,FAT1,HEYL,RAI14,TMEM117,PTPRN2,DISP2,SEMA3A,XKR4,DIRC2,EML5,ZSWIM5,IL15,DOCK1,PLEKHA5,XYLT1,HECW2,COBLL1,PIBF1,RADIL,DOCK2,DDX60L,PCLO,TBC1D19,COL22A1,TACC2,KAZN,REEP1,ZNF521,MAP7,ACVR2A,FHIT,GULP1,PROS1,MDH1B,CLVS2,MET,FAM78B,TMEM56,CTH,FER,UROS,SLC39A8,THSD4,FGF12,ACO1,FBXO36,TPK1,SMAD3,ARMC4,NRG3,PTPRJ,LMLN,RBPMS2,PTPRS,HGF,RNF130,CTNND2,CNTN1,BMPR2,ARHGEF11,GRB14,REL,LRP4,NSUN6,TNFSF13B,CLSTN2,GABRG2,IGF2BP2,USP30,FAM174B,BMP6,PPP2R3A,SLC35F1,CHN2,GTF2F2,PRICKLE2,IPCEF1,RBMS2,MICAL2,CRIM1,CYTH3,OGDHL,GRID1,ASAP3,MEI1,PRRG1,FERMT2,C3orf70,ZFPM2,PALLD,NAALADL2,RERE,MKX,CTIF,EBF1,ADAMTS17,ICA1,DOCK7,EDA,MPP7,L3MBTL4,RND3,FMO4,THSD7B,SLC7A5,RPS12,KIF21A,SLC1A5,KIF1B,MMP16,CACNA2D1,FILIP1 |
| 8.002e-48 | -108.44 | Burkitt_lymphoma | COSMIC cancer mutations | Burkitt_lymphoma | 2173 | 418 | 17385 | 1698 |
ARHGAP26,FAM171B,PLBD2,PPP4R4,PAGE1,LGR4,AASS,RECK,LSM11,PPFIBP2,NPM1,CADM2,KIAA1217,SNX9,DACH2,NOS1AP,PCDH7,EPDR1,TGFBR3,ZFYVE28,DNAH6,SLC16A2,PPFIA2,RAP2A,ATRNL1,PPP2R2B,VWA5A,CPE,EML6,DCDC1,ACVR1C,DCC,CAP2,KLHL4,DSTN,KCND3,GPC6,GNAI1,AHRR,WIPF3,ENPP6,ATP7B,CCBE1,RASGRF2,BDH2,SEMA3C,INPP5F,TANC2,UNC5B,TMEFF2,EFNB2,PTPRD,TBC1D1,CYP2J2,ST6GAL1,OLAH,OPHN1,TJP1,LRRC49,SLC1A3,DYNC1I1,SLC7A11,NOVA2,FAM189A1,MYC,RUNDC3B,PRKG1,SRGAP1,GRIP1,CPXM2,MPDZ,TOX,CADPS2,TSPAN12,ALPK1,FIGN,FAM155A,AGL,GLIS1,PRR16,TSPAN9,COL9A2,FMNL2,LRP12,HMGCR,PTCH2,KCNQ3,TBC1D8B,MYO10,VLDLR,ARID5B,RAPGEF4,RYR2,TTYH2,CALCRL,HIP1,PLS1,AIG1,ST6GALNAC3,CCDC85A,ZBBX,PLCB1,DHX32,CACHD1,XKR9,PLEKHH2,SH3GL2,PMEPA1,ADAMTS3,PELI2,C1orf21,LRRIQ3,DHCR7,CDH2,PLA2G4A,EPHA3,DNM3,TCTN2,RASAL2,ZNF311,MSR1,PLXNA2,IL13RA1,SPATS2L,COLEC10,SLC19A2,TXNRD3,CDS1,COL25A1,NBEA,DNAH5,MYT1,KCNB2,GAB2,TRDMT1,COL6A2,NECAB1,PDK1,KCNH5,SHANK2,ADCY1,NLGN4X,SATB2,TTC28,ASPH,TBC1D16,ZNF618,SNCA,IQCK,ARHGAP21,GYPC,TDO2,PEMT,WWTR1,LAMB1,INPP4B,ZNF704,KLF5,GRB10,CTTNBP2,NR3C2,COBL,STON2,HACE1,ANO10,MYO1D,CCDC148,ROBO2,GLIPR1L1,ATP9A,EPS8,UBAC2,CCNJL,NKAIN2,PSD3,SLC12A6,CREB5,NDFIP2,TPD52L1,COL27A1,NEDD4,LRRC55,GHR,DYNC2H1,MYO6,C15orf41,PARP9,TRPM4,BCL7A,SLC40A1,VAV3,ARHGEF28,CLYBL,PTPN13,ZDHHC15,RASA3,GUCY1A2,SNTB1,SKAP1,GPR137C,HEG1,PTPRC,ID3,PLOD2,PLXDC2,GNAO1,NEK11,HK1,DCBLD1,CRISPLD1,OCLN,BTRC,EXPH5,PHACTR3,CACNG3,HEBP1,ITPR2,FAM13A,NOVA1,DNER,HMCN1,FSTL5,CEP85L,RTN1,SIPA1L2,SEC16B,KCNN2,LRRC6,AKAP7,ABI3BP,SLC10A7,ANKFN1,MPPED2,COL19A1,LIN7A,TRPC1,SLC2A12,TLN2,MYRIP,FANK1,SLIT2,PGBD5,GPM6A,SKAP2,ABCC4,ANK2,JPH1,ROR1,SESN1,SERGEF,EML1,TRIM9,TMEM132B,TCF7L1,KLF12,ITGBL1,NCAM2,MAP2,TECPR2,PPARGC1A,MAGI2,MLLT3,FRMD5,HS6ST3,RRAGD,UST,BCL11B,STXBP5L,FN1,BVES,UBASH3B,ZCCHC24,STXBP6,SETBP1,GALNT13,CHSY1,FAM81A,SATB1,FHOD3,HSPA12B,RNF141,KIAA1958,IGF1R,BCHE,FRAS1,PDE10A,EBF4,FAM107B,LRP6,LIMCH1,SLCO4C1,FBXL2,DPYSL5,CHSY3,CDH26,UNC5C,PCDH10,SDC3,STRADB,SDK1,B4GALNT3,KHDRBS2,NEGR1,GRIK4,KIAA0355,NCR3LG1,FAT1,HEYL,RAI14,TMEM117,PTPRN2,DISP2,SEMA3A,XKR4,DIRC2,EML5,ZSWIM5,IL15,DOCK1,PLEKHA5,XYLT1,HECW2,COBLL1,PIBF1,RADIL,DOCK2,DDX60L,PCLO,TBC1D19,COL22A1,TACC2,KAZN,REEP1,ZNF521,MAP7,ACVR2A,FHIT,GULP1,PROS1,MDH1B,CLVS2,MET,FAM78B,TMEM56,CTH,FER,UROS,SLC39A8,THSD4,FGF12,ACO1,FBXO36,TPK1,SMAD3,ARMC4,NRG3,PTPRJ,LMLN,RBPMS2,PTPRS,HGF,RNF130,CTNND2,CNTN1,BMPR2,ARHGEF11,GRB14,REL,LRP4,NSUN6,TNFSF13B,CLSTN2,GABRG2,IGF2BP2,USP30,FAM174B,BMP6,PPP2R3A,SLC35F1,CHN2,GTF2F2,PRICKLE2,IPCEF1,RBMS2,MICAL2,CRIM1,CYTH3,OGDHL,GRID1,ASAP3,MEI1,PRRG1,FERMT2,C3orf70,ZFPM2,PALLD,NAALADL2,RERE,MKX,CTIF,EBF1,ADAMTS17,ICA1,DOCK7,EDA,MPP7,L3MBTL4,RND3,FMO4,THSD7B,SLC7A5,RPS12,KIF21A,SLC1A5,KIF1B,MMP16,CACNA2D1,FILIP1 |
| 3.548e-37 | -83.93 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | 7517 | 982 | 17385 | 1698 |
ARHGAP26,GXYLT2,FLVCR2,PDE1B,GRIK2,AASS,PRSS12,RECK,DNAJC3,LSM11,NPM1,STAT5B,CTBP2,CEBPA,CADM2,CHAC1,BCAN,DOCK3,KIAA1217,SNX9,CA8,ABHD6,NOS1AP,SKI,PCDH7,EPDR1,TXNDC5,BAG3,FBXO32,TGFBR3,DNAH6,PPFIA2,FAAH2,RAP2A,PPP2R2B,TMEM37,COG3,CPE,KLHL29,TSHR,MEIS2,DCC,TGFA,CAP2,DSTN,ELMOD1,PRKAR2B,ABCC2,F12,MFSD6,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,ARHGAP28,ERCC5,INPP5F,TMEFF2,VASH2,CRYL1,TMEM63C,CYP2J2,ZNF25,TJP1,SLC36A4,GPSM2,CHN1,SYCP2,FRY,KIAA1671,PAIP2B,BACE2,APLF,FAM189A1,CACNB2,PRELID2,SRGAP1,TOX,CADPS2,ALPK1,ST8SIA1,LOXL4,FIGN,NCAM1,MOXD1,JAM2,AGL,STXBP1,TSPAN9,FMNL2,LRP12,CHRM3,HMGCR,BDNF,SLC37A1,KCNQ3,MYO10,STAT4,SPATA6,ARID5B,FASN,RYR2,HIP1,SMARCD3,CALCRL,PLS1,AIG1,ST6GALNAC3,SHISA2,ZBBX,TAF4B,ARRDC4,MBNL2,DHX32,BEX4,CACHD1,TEX15,TMCO3,RIMKLB,GSTO2,SH3GL2,ADAMTS3,QPCTL,EMILIN2,CDH17,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,NUDT10,DNM3,ZNF516,GALNT12,RGS20,BEGAIN,PKP2,ADD2,IL13RA1,COLEC10,LCP2,SLC19A2,TXNRD3,CDS1,RNF150,EPB41L3,TLR3,KMO,COL25A1,CNKSR3,ALDH1L1,RTKN2,RPL26L1,JAKMIP3,DNAH5,ANKRD18B,KCNB2,DOCK8,SCN3A,C3orf67,DZANK1,MYLK3,COL6A2,GAPDH,RNF145,NECAB1,PFKFB2,ADM2,KCNH5,ADCY1,RAB38,TTC28,DSP,ASPH,ZNF618,METAP1D,FGFR1,GABARAPL1,IRS2,IQCK,ARHGAP21,IQCH,GYPC,PDLIM3,WFS1,PEMT,WWTR1,LAMB1,INPP4B,PLEKHG1,TNFSF15,FAM149A,HOXB9,RAB30,CCDC148,FARP1,WDR17,C1QTNF3,ROBO2,CKAP2,CD276,UBAC2,NKAIN2,PSD3,CBS,CREB5,TSPAN17,BEX2,COL27A1,NEO1,HMGCS1,GAS2L3,GHR,MYO6,NPTXR,C15orf41,MED12L,ULBP1,TRPM4,B9D1,MN1,BCL7A,LCA5,RAB6B,CLYBL,MCF2L2,RAPGEF2,AK4,RASA3,ATP11A,SNTB1,HEG1,PTPRC,ID3,NSD1,PCDHB7,PLOD2,GNAO1,XBP1,SLCO5A1,NEK11,HK1,CMPK2,SHOX2,DOCK6,ATP2B4,DCBLD1,CRISPLD1,BTRC,TLL2,CCDC126,PHACTR3,NBPF4,CACNG3,SYT12,LMCD1,LILRB1,NRN1,ITPR2,SYT14,FAM13A,NOVA1,FSTL5,PLS3,RUFY4,FKBP9,TM9SF2,EOMES,CPVL,SEC16B,AADAT,KCNN2,MARVELD2,ITGB3,TMEM143,MPPED2,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TMEM132E,ETV1,PGBD5,SLC3A2,MARK1,KCNIP3,ABCC4,COL4A3,ANK2,PLEKHA1,BATF,TCERG1L,SESN1,CRYBG3,NT5DC2,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,MAP2,P4HA2,GNB4,TECPR2,ERN1,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,TC2N,HS6ST3,RRAGD,CHMP4C,LONRF1,KCNV1,STXBP5L,UBASH3B,ZCCHC24,SETBP1,SORBS3,MLC1,IL18R1,PGAP1,DOK5,FHOD3,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,ABCA5,BCHE,FRAS1,PDE10A,SAMD11,GAN,HS3ST5,LRP6,SLCO4C1,FAR2,NIPAL2,FBXL2,VGLL4,CHSY3,DPYSL5,MID2,UNC5C,BTNL9,SLC27A2,RNF170,EFNA3,TMTC4,PPFIA4,WDR25,OBSCN,PDE8A,SDK1,KHDRBS2,TEX9,NEGR1,GRIK4,ATPAF2,HEYL,PLD1,SEMA3A,RNF122,TESC,MME,CFH,DOCK1,LPCAT2,XYLT1,RHPN2,NTRK3,KIF21B,SEZ6L2,LPIN3,DENND3,KBTBD11,RADIL,SEMA6A,PCLO,DDX60L,TBC1D19,TACC2,ZDHHC6,MYO3B,BCL6,EEPD1,ZDHHC23,MYH15,CLVS2,FAM78B,TMEM56,GLI1,HRASLS,INTU,EVL,UROS,TMEM65,THSD4,FGF12,RNF125,CHRNA6,FBXO36,FRK,PAGE5,JAM3,SMAD3,RANBP2,NRG3,PTPRJ,RNF217,PTK7,GBP1,ITGA2,ABI3,MAOA,HGF,MBOAT2,CTNND2,CNTN1,MAN2B2,COL9A3,PCDH18,LPAR2,NECAB2,BMPR2,KLHL13,GRB14,RUSC2,APBB1,MCTP2,BLVRB,GABRG2,HBE1,USP30,ARHGAP44,PPP2R3A,SLC35F1,TTC1,TECPR1,MAP1A,RASD2,GTF2F2,TSC22D1,SGK1,PRICKLE2,SH3PXD2B,ESD,KIAA1211,ATP2B1,DLGAP1,MICAL2,LITAF,PRICKLE1,FERMT2,FNDC3A,PALLD,ILDR2,SMPDL3B,HOMER3,MKX,EBF1,DDAH1,CD37,DOCK7,TMEM237,FAT4,FBN1,L3MBTL4,FMO4,SH3BGRL2,DLG2,PAX9,THAP10,TBC1D4,KIF1B,FILIP1,CACNA2D1,FAM171B,CGN,PPP4R4,ACVR1,PAGE1,LGR4,SIDT1,TCP11L2,ATP8A1,LDLR,PPFIBP2,GATA3,ENAH,PRKCA,AARS,DACH2,SLC9A7,STK24,NCS1,HECTD2,ZFYVE28,FAM168A,CFHR1,SLC22A18,SLC16A2,SERINC2,CHRDL1,KCNS3,GSTM3,ATRNL1,BEND4,PACSIN1,RCAN3,THSD1,GLDC,ERGIC1,EML6,DCDC1,ACVR1C,NR6A1,KLHL3,KLHL4,ALDH1L2,DNAJC6,BNIP3L,DEPTOR,MEF2B,TNS1,EFHC1,ACVR2B,ZDHHC14,ARHGEF26,GPC6,GNAI1,AHRR,SFXN1,SPATA9,SH3RF1,ENPP6,NCKAP1L,ENTPD7,RASGRF2,CCBE1,B3GALT2,BMP1,SEMA3C,SERPINI1,SPRY4,NRP1,TANC2,UNC5B,LZTS1,EFNB2,LRFN5,KLF8,MRC2,FAM124A,CELSR1,EHHADH,PTPRD,ZHX3,TBC1D1,SCN8A,ST6GAL1,OLAH,SLC25A27,OPHN1,GTF2IRD1,LRRC49,SLC1A3,WDFY4,APBA1,TNFRSF19,ADSSL1,DYNC1I1,PRRG4,MTUS1,MCOLN2,ABLIM1,NAV1,SLC7A11,RALGPS2,KIAA1257,NOVA2,PIK3AP1,MYC,RUNDC3B,OPN3,SREBF1,PRKG1,CPXM2,GRIP1,SLC16A9,MPDZ,TSPAN12,SAMD13,PRR16,FAM155A,COL9A2,BOD1,EPB41L5,QSOX1,RPL26,TBC1D8B,COL4A4,RAPGEF4,TTYH2,PEX5L,CCDC85A,PLCB1,FAM162A,ZNF558,XKR9,PLEKHH2,PMEPA1,PKN3,ISM1,PELI2,THBS4,C1orf21,LRRIQ3,MPP2,DYNC2LI1,SQLE,SLFN5,SMYD3,AMPD1,ACSM3,FRMPD3,EPHA3,PLA2G4A,AMOTL1,ELOVL4,RASAL2,RNF144A,MSR1,PLXNA2,CHUK,SPATS2L,NUDT12,COL14A1,ZFYVE9,TIAM2,ZNF827,SPEG,ZNF438,NBEA,GAB2,TRDMT1,VNN2,PDK1,SFXN4,SHANK2,PANK1,PREX1,NLGN4X,SATB2,PRKCQ,PYGO1,ATP1B1,TBC1D16,ATP10D,SNCA,ISG20,HTR7,IKZF3,PRKCB,TDO2,ZNF704,HPGD,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,COBL,STON2,PURG,MID1,HACE1,DENND5B,WASF3,ANO10,MYO1D,MXI1,PLSCR4,GLIPR1L1,ATP9A,EPS8,CCNJL,HERC5,NDFIP2,GDPD5,TPD52L1,NEDD4,RASSF8,RGS17,SOAT2,GPR155,SLC6A15,DYNC2H1,FIG4,SMAD6,B4GALT6,TMC7,VAV3,ARHGEF28,GSTM2,ARAP2,AGPAT4,CACNA1E,PTPN13,TMEM126A,RPL21,ZDHHC15,CTTNBP2NL,UCHL3,GUCY1A2,SKAP1,GPR137C,ZIC1,FGR,TERT,PLXDC2,PGM2L1,TUFT1,SVIL,GRIN2D,MYOM2,CERS1,OCLN,MPZL3,EXPH5,UGT8,PTPN21,ACTL8,C20orf194,ANKRD18A,IKZF2,RBM11,DNER,KREMEN1,SLCO3A1,HMCN1,CEP85L,CHST10,QPRT,RTN1,ARHGEF10L,ADPRHL1,LGI2,EPCAM,PPM1E,SIPA1L2,LRRC6,AKAP7,SLC10A7,ANKFN1,POF1B,TRPC1,SLC2A12,PCOLCE2,PTPRE,MYRIP,FANK1,SLIT2,RASGRP1,PRKACB,LAMP3,ATL1,GPM6A,SESN2,SKAP2,CAPN5,JPH1,ROR1,COTL1,SGK2,SERGEF,EML1,TMEM132B,HPSE,ITGBL1,NCAM2,CCDC169,NCOA7,PPARGC1A,APBA2,MAGI2,FRMD5,GPT2,UST,BCL11B,SV2B,MOCOS,FN1,RHOBTB1,SEC24D,SCART1,STXBP6,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,CHSY1,FAM81A,PHGDH,SATB1,CD7,CA2,ZNF354A,EEF2,EBF4,FAM107B,LIMCH1,RNF148,LRP3,NOS3,CDH26,GPR176,PCDH10,PODXL2,SLITRK2,PARD3B,WWC1,LHPP,PRDM1,B4GALNT3,STEAP1,HERPUD1,GLCE,TMEM154,KIAA0355,NCR3LG1,FAT1,HK2,RAI14,RAB31,SH3BP4,TMEM117,NXPH4,PTPRN2,XKR4,DIRC2,CREB3L2,CXCR5,DMXL2,EML5,ZSWIM5,IL15,CELSR3,PLEKHA5,HECW2,MORC4,COL18A1,COBLL1,PIBF1,DOCK2,SCIN,COL22A1,PDZD8,SETDB2,UNC13B,KAZN,REEP1,ZNF521,MAP7,ACVR2A,FHIT,GULP1,PROS1,MDH1B,WWC2,MET,POU2F2,TMEM120B,ZNF460,SUSD3,DPP10,PRAME,FER,GCA,PTPRU,SLC39A8,TES,SYNJ2BP,CD40,TTLL7,DOCK5,TPK1,BATF3,WARS,BCL11A,ZNF569,ARMC4,ZNF93,KPNA3,TMPRSS9,DUSP19,SOHLH2,DISP1,CYP2U1,RNF130,LIFR,MAST1,TNIK,ARHGEF11,CLGN,TSPAN15,REL,CMTM8,LRP4,TNFSF13B,NSUN6,CLSTN2,COL4A5,IGF2BP2,FAM174B,SEL1L3,BMP6,MCU,CHN2,PRKCD,STC2,EHD3,KIAA0319,CCDC122,TRIM3,MARCH3,AFAP1L2,IPCEF1,RRAS2,TNFRSF11A,RBMS2,RAB3B,CRIM1,ESRRG,SYBU,CYTH3,OGDHL,GRID1,ASAP3,MEI1,PRRG1,MARS,PHACTR2,C3orf70,ZFPM2,GALNT14,NAALADL2,MAP1B,RERE,CTIF,ADAMTS17,GPR37,DPY19L2,ICA1,MFSD9,EDA,MPP7,NACC2,RND3,ACER2,MAP2K6,THSD7B,KIF21A,GEM,IL9R,MMP16,NPHP1,MAP3K20,SLC16A10,ABCG1,STOM |
| 1.450e-36 | -82.52 | GOZGIT_ESR1_TARGETS_DN | MSigDB lists | GOZGIT_ESR1_TARGETS_DN | 680 | 179 | 17377 | 1707 |
TRIM2,DUSP8,SIDT1,FGF13,UGDH,MCOLN3,LMCD1,GATA3,ENAH,ABAT,PRKCA,ABHD4,CACNB4,HMCN1,PCDH7,TRPS1,BAG3,SIPA1L2,PPM1E,FBXO32,RPS6KA2,C1orf53,MPPED2,POF1B,ATRNL1,LIN7A,CPE,SLIT2,RASGRP1,CYP1B1,KLHL23,CAP2,WLS,TGFA,FAM84A,DEPTOR,BATF,PLEKHB1,GSN,ENPP1,NCAM2,MAP2,PLK2,CCDC169,SEMA3C,CAB39L,INPP5F,TANC2,NRP1,MLLT3,TC2N,EFNB2,RUNX2,SEC24D,ITGA6,YPEL2,HERC6,PFN2,EFEMP1,PCDHB14,ABLIM1,PRTFDC1,IGF1R,ABCA5,RPS11,FLRT3,FRAS1,RUNDC3B,SRGAP1,HS3ST5,MPDZ,FIGN,FAR2,MAST4,GFRA1,CKAP4,EPB41L5,MID2,PCDH10,RHOQ,SLC37A1,SLC27A2,ARID5B,VLDLR,SPATA13,SDK1,NPC2,PLCB1,SLC46A3,TBC1D2,BEX4,PMEPA1,FAT1,CREB3L2,EPHA3,DNM3,AKAP5,PLEKHA5,PSTPIP2,RBFOX2,MYO1B,LRRCC1,COBLL1,COL18A1,FAM198B,SLC7A2,SLC19A2,NELL2,KCTD15,BCL6,NBEA,SCRN1,GULP1,MARCKS,RAB27B,SP140L,DOCK8,C3orf67,EVL,NECAB1,TUBA1A,SLC39A8,THSD4,SHANK2,ADCY1,TCEAL3,ATP1B1,TPK1,GABARAPL1,ISG20,HTR7,INPP4B,MAOA,SUSD4,TTC39A,STON2,CTNND2,FARP1,IGFBP6,TSPAN15,ATP9A,PRSS35,SELL,PSD3,RASD1,COL4A5,SLC12A6,FUT9,STC2,PRICKLE2,SGK1,TSPAN13,KLF9,TBC1D9,MYO6,RBMS2,PCSK6,VEGFC,VAV3,SYNPO2,LCA5,PTPN13,ZDHHC15,AK4,C3orf70,GPR137C,LEPR,DKK1,GPR37,PCDHB7,RND3,XBP1,KIAA0513,PGM2L1,SH3BGRL2,HK1,MMP16,PKIA,FOXA1 |
| 2.168e-35 | -79.82 | diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | diffuse_large_B_cell_lymphoma | 4283 | 636 | 17385 | 1698 |
DOC2A,THOC5,AASS,DNAJC3,NPM1,STAT5B,CTBP2,CADM2,KIAA1217,SNX9,NOS1AP,PCDH7,DNAH6,PPFIA2,FAAH2,PPP2R2B,COG3,CPE,MEIS2,SMAD9,DCC,WLS,EXOC6B,TGFA,CAP2,ELMOD1,FEZ1,PRKAR2B,INTS6,ERCC5,TMEFF2,CRYL1,MEF2C,CARS,ITGA6,TJP1,SLC36A4,GPSM2,CHN1,SYCP2,FRY,FAM189A1,ZIC5,PRELID2,SRGAP1,TOX,CADPS2,ST8SIA1,FIGN,NCAM1,MOXD1,JAM2,AGL,GLIS1,FMNL2,LRP12,CHRM3,FADS1,BDNF,PNP,KCNQ3,MYO10,STAT4,SPATA6,ARID5B,RYR2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,TAF4B,MBNL2,DHX32,BEX4,CACHD1,TMCO3,RIMKLB,SH3GL2,ADAMTS3,LAPTM4B,CDH2,DOCK9,MTG1,DNM3,ZNF516,PKP2,SLC19A2,TXNRD3,CDS1,GPR15,EPB41L3,CHRNA5,KMO,COL25A1,CNKSR3,ALDH1L1,FAM133A,DNAH5,KCNB2,SCN3A,C3orf67,DZANK1,RNF145,NECAB1,EBPL,KCNH5,RAB38,TTC28,DSP,ASPH,METAP1D,FGFR1,IRS2,IQCK,ARHGAP21,IQCH,WFS1,PEMT,WWTR1,LAMB1,INPP4B,PLEKHG1,P4HA1,LRRC27,CCDC148,FARP1,C1QTNF3,ROBO2,BACE1,NKAIN2,PSD3,CREB5,PKN1,NEO1,GHR,MYO6,NPTXR,MED12L,B9D1,MN1,BCL7A,LCA5,CLYBL,RAPGEF2,RASA3,SNTB1,PTPRC,ID3,NSD1,RPL12,PLOD2,GNAO1,OSBPL5,XBP1,SLCO5A1,NEK11,DCBLD1,CRISPLD1,BTRC,TLL2,PHACTR3,LMCD1,ASS1,LILRB1,ITPR2,FAM13A,NOVA1,FSTL5,ANKRD42,FKBP9,TM9SF2,CPVL,SEC16B,KCNN2,ITGB3,MPPED2,COL19A1,LIN7A,JAKMIP2,TLN2,TLR4,PGBD5,DBN1,KCNIP3,ATF4,ABCC4,SPOCD1,ANK2,BATF,TCERG1L,TCF7L1,KLF12,MAP2,TECPR2,TNFRSF1A,PIK3C2B,MLLT3,TC2N,HS6ST3,RRAGD,KCNV1,STXBP5L,SETBP1,PGAP1,DOK5,FHOD3,EFEMP1,PRTFDC1,IGF1R,BCHE,FRAS1,LRP6,SLCO4C1,FBXL2,VGLL4,PAK1,FGFR4,CHSY3,MID2,UNC5C,SPATA13,WDR25,PDE8A,SDK1,KHDRBS2,NEGR1,GRIK4,PLD1,SEMA3A,MME,SIX2,CFH,DOCK1,LPCAT2,XYLT1,RHPN2,KIF21B,DENND3,RADIL,PPP1R9A,SEMA6A,PCLO,DDX60L,TACC2,MYO3B,BCL6,EEPD1,MYH15,CLVS2,HRASLS,INTU,EVL,TMEM65,TDRD3,LRRC8B,THSD4,FGF12,RNF125,FBXO36,JAM3,SMAD3,NRG3,PTK7,ITGA2,ABI3,MAOA,HGF,SUSD4,CTNND2,CNTN1,NECAB2,BMPR2,GRB14,APBB1,MCTP2,GABRG2,ARHGAP44,SLC35F1,FOXP2,TSC22D1,SGK1,PRICKLE2,SH3PXD2B,DLGAP1,MICAL2,FNDC3A,PALLD,SMPDL3B,EBF1,DDAH1,FAT4,FBN1,L3MBTL4,ZNF214,SH3BGRL2,ZNF474,THAP10,TBC1D4,PTGES,KIF1B,CACNA2D1,FILIP1,ZNF235,FAM171B,CGN,PPP4R4,LGR4,DUSP8,ATP8A1,GATA3,ENAH,PRKCA,DACH2,HECTD2,TRPS1,TYMP,ZFYVE28,SLC16A2,SERINC2,CHRDL1,ATRNL1,BEND4,SP140,VWA5A,RCAN3,ERGIC1,DCDC1,EML6,NR6A1,KLHL4,ALDH1L2,LRMP,DEPTOR,MEF2B,GPC6,GNAI1,NCKAP1L,SH3RF1,RASGRF2,CCBE1,BMP1,DSEL,SEMA3C,TANC2,NRP1,EFNB2,CELSR1,EHHADH,PTPRD,TBC1D1,SCN8A,OLAH,OPHN1,GTF2IRD1,LRRC49,WDFY4,SLC1A3,APBA1,DYNC1I1,TNFRSF19,PRRG4,MTUS1,MCOLN2,NAV1,RALGPS2,ADCK1,PIK3AP1,MYC,RUNDC3B,PRKG1,CPXM2,GRIP1,SLC16A9,MPDZ,TSPAN12,SAMD13,PRR16,FAM155A,COL9A2,GPR161,RIMS2,EPB41L5,PTCH2,TBC1D8B,COL4A4,DCHS1,TTC30A,PEX5L,CCDC85A,CDC42BPA,PLCB1,PLEKHH2,PKN3,ISM1,PELI2,THBS4,C1orf21,LRRIQ3,SFMBT1,SQLE,ACSM3,FRMPD3,EPHA3,PLA2G4A,RASAL2,ST14,RNF144A,CCDC110,ZNF311,PLXNA2,MSR1,COL14A1,NUDT12,ZFYVE9,TIAM2,SPEG,NELL2,ZNF438,SHF,NAP1L3,ATP6AP1L,SHANK2,PANK1,NLGN4X,ATF3,PRKCQ,SATB2,TBC1D16,SNCA,IKZF3,PRKCB,ZNF704,GRB10,BMPR1A,CTTNBP2,NR3C2,STON2,MID1,COBL,DENND5B,HACE1,ANO10,WASF3,MYO1D,MXI1,ATP9A,EPS8,NDFIP2,TPD52L1,NEDD4,AFF2,SLC6A15,DYNC2H1,SMAD6,B4GALT6,VAV3,ARAP2,ARHGEF28,AGPAT4,CACNA1E,PTPN13,ZDHHC15,CTTNBP2NL,GUCY1A2,SKAP1,GPR137C,GPLD1,TERT,PLXDC2,MCC,SVIL,PGM2L1,GRIN2D,MYOM2,OCLN,EXPH5,PTPN21,UGDH,ABAT,DNER,IKZF2,HMCN1,SLCO3A1,CEP85L,RTN1,CYP51A1,ARHGEF10L,SIPA1L2,PPM1E,ABI3BP,ANKFN1,SLC10A7,TRPC1,POF1B,SLC2A12,CTTN,PTPRE,MYRIP,FANK1,SLIT2,GPM6A,SKAP2,CAPN5,ROR1,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,OXTR,PPARGC1A,MAGI2,FRMD5,PCSK5,UST,BCL11B,MOCOS,FN1,RHOBTB1,SEC24D,STXBP6,JDP2,LAMC3,GALNT13,OTUD1,SLC30A4,ZNF354A,FAM107B,LIMCH1,NCEH1,LRP3,CDH26,GPR176,PCDH10,DUSP9,LHPP,PRDM1,B4GALNT3,HERPUD1,TMEM154,KIAA0355,FAT1,PTPRN2,NXPH4,TMEM117,XKR4,CXCR5,DMXL2,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,HECW2,COBLL1,PIBF1,UBTD2,DOCK2,CD53,SCIN,COL22A1,UNC13B,PDZD8,KAZN,PPFIBP1,ZNF521,FHIT,PROS1,GULP1,POU2F2,MET,TMEM120B,SEMA6C,DPP10,FER,TTLL7,DOCK5,BATF3,TPK1,ARMC4,ZNF93,KPNA3,RBPMS2,SOHLH2,RNF130,LIFR,MAST1,OR51B5,TNIK,ARHGEF11,CLGN,REL,CMTM8,NSUN6,CLSTN2,IGF2BP2,SEL1L3,BMP6,MCU,CHN2,DSG2,STC2,KIAA0319,AFAP1L2,TNFRSF11A,CARD6,CRIM1,ESRRG,GRID1,ASAP3,OGDHL,MEI1,PHACTR2,ZFPM2,C3orf70,GALNT14,NAALADL2,MAP1B,RERE,CTIF,GPR37,DPY19L2,ADAMTS17,ICA1,EDA,NACC2,MPP7,RND3,MAP2K6,THSD7B,KIF21A,MAP3K20,NPHP1,MMP16 |
| 1.031e-32 | -73.65 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 3717 | 563 | 17385 | 1698 |
DOC2A,THOC5,AASS,DNAJC3,NPM1,CADM2,KIAA1217,SNX9,NOS1AP,PCDH7,DNAH6,PPFIA2,FAAH2,PPP2R2B,COG3,CPE,MEIS2,DCC,TGFA,CAP2,ELMOD1,FEZ1,PRKAR2B,INTS6,ERCC5,TMEFF2,CRYL1,MEF2C,CARS,TJP1,SLC36A4,GPSM2,CHN1,SYCP2,FRY,FAM189A1,PRELID2,SRGAP1,TOX,CADPS2,ST8SIA1,FIGN,NCAM1,MOXD1,JAM2,AGL,GLIS1,FMNL2,LRP12,BDNF,KCNQ3,MYO10,STAT4,SPATA6,ARID5B,RYR2,HIP1,AIG1,ST6GALNAC3,ZBBX,TAF4B,MBNL2,DHX32,BEX4,CACHD1,RIMKLB,SH3GL2,ADAMTS3,LAPTM4B,CDH2,DOCK9,MTG1,DNM3,ZNF516,PKP2,SLC19A2,TXNRD3,CDS1,GPR15,EPB41L3,CHRNA5,KMO,CNKSR3,COL25A1,ALDH1L1,DNAH5,KCNB2,SCN3A,C3orf67,DZANK1,RNF145,NECAB1,EBPL,KCNH5,RAB38,TTC28,DSP,ASPH,METAP1D,FGFR1,IRS2,IQCK,ARHGAP21,IQCH,PEMT,WWTR1,LAMB1,INPP4B,PLEKHG1,P4HA1,CCDC148,FARP1,C1QTNF3,ROBO2,BACE1,NKAIN2,PSD3,CREB5,PKN1,NEO1,GHR,MYO6,NPTXR,MED12L,B9D1,MN1,BCL7A,CLYBL,RAPGEF2,RASA3,SNTB1,PTPRC,NSD1,RPL12,PLOD2,GNAO1,OSBPL5,SLCO5A1,NEK11,DCBLD1,CRISPLD1,BTRC,TLL2,PHACTR3,LMCD1,ASS1,ITPR2,FAM13A,NOVA1,FSTL5,ANKRD42,FKBP9,TM9SF2,CPVL,SEC16B,KCNN2,ITGB3,MPPED2,COL19A1,LIN7A,JAKMIP2,TLN2,TLR4,PGBD5,DBN1,KCNIP3,ATF4,ABCC4,SPOCD1,ANK2,BATF,TCERG1L,TCF7L1,KLF12,TECPR2,PIK3C2B,MLLT3,TC2N,HS6ST3,RRAGD,STXBP5L,SETBP1,PGAP1,DOK5,FHOD3,EFEMP1,PRTFDC1,IGF1R,BCHE,FRAS1,LRP6,SLCO4C1,FBXL2,VGLL4,CHSY3,UNC5C,SPATA13,WDR25,PDE8A,SDK1,KHDRBS2,NEGR1,GRIK4,PLD1,SEMA3A,MME,SIX2,CFH,DOCK1,LPCAT2,XYLT1,RHPN2,KIF21B,DENND3,RADIL,PCLO,DDX60L,TACC2,EEPD1,BCL6,MYH15,CLVS2,HRASLS,INTU,EVL,TMEM65,TDRD3,LRRC8B,THSD4,FGF12,RNF125,FBXO36,JAM3,SMAD3,NRG3,PTK7,ITGA2,ABI3,MAOA,HGF,CTNND2,CNTN1,NECAB2,BMPR2,GRB14,APBB1,MCTP2,GABRG2,ARHGAP44,SLC35F1,TSC22D1,SGK1,PRICKLE2,SH3PXD2B,DLGAP1,MICAL2,FNDC3A,PALLD,SMPDL3B,EBF1,DDAH1,FAT4,FBN1,SH3BGRL2,ZNF474,TBC1D4,PTGES,KIF1B,CACNA2D1,FILIP1,ZNF235,FAM171B,PPP4R4,LGR4,DUSP8,ATP8A1,ENAH,PRKCA,DACH2,HECTD2,TYMP,ZFYVE28,SLC16A2,SERINC2,CHRDL1,ATRNL1,BEND4,SP140,VWA5A,ERGIC1,DCDC1,EML6,NR6A1,KLHL4,ALDH1L2,LRMP,DEPTOR,MEF2B,GPC6,GNAI1,NCKAP1L,SH3RF1,RASGRF2,CCBE1,BMP1,SEMA3C,TANC2,NRP1,EFNB2,CELSR1,EHHADH,TBC1D1,SCN8A,OLAH,OPHN1,LRRC49,WDFY4,APBA1,DYNC1I1,TNFRSF19,PRRG4,MTUS1,MCOLN2,NAV1,RALGPS2,PIK3AP1,MYC,PRKG1,RUNDC3B,CPXM2,GRIP1,SLC16A9,TSPAN12,SAMD13,PRR16,FAM155A,COL9A2,GPR161,EPB41L5,PTCH2,COL4A4,DCHS1,PEX5L,CCDC85A,PLCB1,PLEKHH2,PKN3,ISM1,PELI2,THBS4,LRRIQ3,C1orf21,SFMBT1,SQLE,ACSM3,FRMPD3,EPHA3,PLA2G4A,RASAL2,ST14,RNF144A,CCDC110,PLXNA2,MSR1,COL14A1,NUDT12,TIAM2,ZFYVE9,SPEG,NELL2,ZNF438,SHF,ATP6AP1L,SHANK2,PANK1,NLGN4X,PRKCQ,SATB2,TBC1D16,SNCA,IKZF3,PRKCB,ZNF704,GRB10,BMPR1A,CTTNBP2,NR3C2,STON2,MID1,COBL,DENND5B,HACE1,WASF3,ANO10,MYO1D,MXI1,ATP9A,EPS8,NDFIP2,TPD52L1,NEDD4,SLC6A15,DYNC2H1,SMAD6,VAV3,ARAP2,ARHGEF28,AGPAT4,PTPN13,ZDHHC15,CTTNBP2NL,GUCY1A2,SKAP1,GPR137C,GPLD1,TERT,PLXDC2,MCC,SVIL,MYOM2,GRIN2D,OCLN,PTPN21,ABAT,DNER,IKZF2,HMCN1,SLCO3A1,CEP85L,CYP51A1,RTN1,SIPA1L2,PPM1E,ANKFN1,SLC10A7,TRPC1,POF1B,SLC2A12,MYRIP,FANK1,SLIT2,GPM6A,SKAP2,CAPN5,ROR1,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,OXTR,PPARGC1A,MAGI2,FRMD5,UST,BCL11B,MOCOS,SEC24D,RHOBTB1,STXBP6,JDP2,GALNT13,SLC30A4,ZNF354A,FAM107B,LIMCH1,LRP3,CDH26,PCDH10,GPR176,LHPP,PRDM1,HERPUD1,TMEM154,KIAA0355,FAT1,PTPRN2,NXPH4,TMEM117,XKR4,DMXL2,EML5,ZSWIM5,PLEKHA5,HECW2,COBLL1,PIBF1,DOCK2,UBTD2,CD53,SCIN,COL22A1,UNC13B,PDZD8,KAZN,PPFIBP1,ZNF521,FHIT,PROS1,GULP1,POU2F2,MET,TMEM120B,FER,DOCK5,TTLL7,BATF3,TPK1,ARMC4,ZNF93,KPNA3,RBPMS2,SOHLH2,RNF130,LIFR,MAST1,TNIK,ARHGEF11,CLGN,REL,CMTM8,NSUN6,CLSTN2,IGF2BP2,SEL1L3,BMP6,MCU,CHN2,DSG2,STC2,KIAA0319,AFAP1L2,TNFRSF11A,CARD6,CRIM1,ESRRG,ASAP3,GRID1,OGDHL,MEI1,PHACTR2,ZFPM2,C3orf70,GALNT14,NAALADL2,CTIF,RERE,MAP1B,GPR37,DPY19L2,ADAMTS17,ICA1,EDA,NACC2,MPP7,RND3,MAP2K6,THSD7B,KIF21A,MAP3K20,NPHP1,MMP16 |
| 1.276e-32 | -73.44 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | 2583 | 429 | 17385 | 1698 |
ARHGAP26,FAM171B,CGN,GXYLT2,ACVR1,TCP11L2,AASS,PRSS12,ATP8A1,DNAJC3,PPFIBP2,CTBP2,CADM2,BCAN,PRKCA,KIAA1217,SNX9,ABHD6,SLC9A7,HECTD2,SKI,TXNDC5,BAG3,DNAH6,SLC16A2,PPFIA2,CHRDL1,ATRNL1,PPP2R2B,COG3,THSD1,CPE,GLDC,MEIS2,EML6,DCDC1,DCC,ALDH1L2,CAP2,KLHL4,SLC25A28,PRKAR2B,ABCC2,TNS1,ZDHHC14,CA13,GPC6,GNAI1,AHRR,SH3RF1,ATP7B,CCBE1,RASGRF2,MAP9,ARHGAP28,SEMA3C,INPP5F,ZBTB20,CAB39L,NRP1,DNHD1,TMEFF2,EFNB2,LRFN5,LATS2,MRC2,CELSR1,TBC1D1,GABRB2,OPHN1,SLC25A27,MRPL22,TJP1,SLC1A3,WDFY4,GPSM2,APBA1,DYNC1I1,MCOLN2,BNIP1,FRY,KIAA1257,KIAA1671,APLF,FAM189A1,PRKG1,SRGAP1,GRIP1,TOX,CADPS2,ALPK1,SAMD13,FIGN,NCAM1,FAM155A,PRR16,FMNL2,SLC37A1,KCNQ3,TBC1D8B,SPATA6,RAPGEF4,DCHS1,FHL2,RYR2,AIG1,ST6GALNAC3,PEX5L,TAF4B,PLCB1,MBNL2,CACHD1,RIMKLB,SH3GL2,ADAMTS3,PELI2,CECR2,C1orf21,LRRIQ3,EMILIN2,DYNC2LI1,SLFN5,CDH2,AMPD1,EPHA3,DNM3,ZNF516,TCTN2,RASAL2,ST14,ZNF311,PLXNA2,BEGAIN,RGS20,PKP2,CHUK,SPATS2L,COLEC10,COL14A1,EPB41L3,ZNF827,ZNF438,KMO,COL25A1,CNKSR3,NBEA,ATP6AP1L,GATM,KCNB2,C3orf67,GAB2,MYLK3,KCNH5,SHANK2,ADCY1,PREX1,NLGN4X,PRKCQ,TTC28,DSP,ASPH,HTR7,ARHGAP21,IKZF3,IQCH,KLHL31,CTTNBP2,NR3C2,COBL,MID1,STON2,PURG,HACE1,ANO10,MYO1D,WDR17,ROBO2,BACE1,EPS8,UBAC2,NKAIN2,PSD3,CREB5,TPD52L1,COL27A1,GPR155,SGK3,RALGAPA2,SLC6A15,MYO6,TBC1D9,C15orf41,SMPDL3A,MED12L,B4GALT6,PARP9,VAV3,SYNPO2,ARAP2,LCA5,CLYBL,MCF2L2,RAPGEF2,RASA3,ATP11A,CTTNBP2NL,GUCY1A2,SNTB1,SKAP1,PLOD2,PLXDC2,OSBPL5,SLCO5A1,SVIL,NEK11,MYOM2,DOCK6,BTRC,NUDT17,PHACTR3,UGT8,SYT12,PTPN21,FHDC1,LILRB1,ANKRD18A,ITPR2,FAM13A,DNER,IKZF2,KREMEN1,SLCO3A1,HMCN1,FSTL5,PLS3,ANKRD42,RTN1,PPM1E,FKBP9,KCNN2,AKAP7,SLC10A7,ITGB3,ANKFN1,COL19A1,POF1B,LIN7A,JAKMIP2,MYRIP,NEB,SLIT2,RAPGEF5,LAMP3,PGBD5,GPM6A,ABCC4,SPOCD1,ANK2,GDPD1,CR2,ROR1,COTL1,SGK2,SESN1,CRYBG3,SERGEF,TMEM132B,TCF7L1,KCNMB4,KLF12,ITGBL1,NCAM2,FAM114A2,CCDC146,DLX2,MAGI2,MLLT3,HS6ST3,CHMP4C,FN1,UBASH3B,STXBP6,ELOVL7,RIMKLA,CYP4V2,GALNT13,CHSY1,FAM81A,MLC1,SPINK5,SATB1,DOK5,FHOD3,GALNT1,CA2,IGF1R,FRAS1,SAMD11,FAM107B,LIMCH1,FBXL2,BARX1,CAND2,CKAP4,SNX7,NOS3,ZNF629,CHSY3,GPR176,UNC5C,PODXL2,TMTC4,WDR25,OBSCN,PDE8A,SDK1,LHPP,KHDRBS2,HERPUD1,NEGR1,GRIK4,KIAA0355,FAT1,CSF1,RAI14,TMEM117,PTPRN2,SEMA3A,XKR4,MME,SFN,DMXL2,EML5,DOCK1,PLEKHA5,HECW2,COL18A1,RHPN2,COBLL1,DOCK2,CYP26A1,COL22A1,TACC2,KAZN,ZDHHC6,ZNF521,MAP7,MYH15,FHIT,FAM78B,FER,UROS,THSD4,TES,C3orf52,FGF12,ACO1,VIM,TTLL7,DOCK5,TPK1,BCL11A,ZNF569,NRG3,PTPRJ,LMLN,BACH2,PTK7,RBPMS2,MAOA,HGF,SUSD4,LIFR,CTNND2,PSPH,TENM1,TNIK,BMPR2,ARHGEF11,GRB14,ARL15,MCTP2,NSUN6,CLSTN2,GABRG2,SELL,SEL1L3,BMP6,PPP2R3A,SLC35F1,CHN2,RASD2,KCNMB3,TSC22D1,KIAA0319,PRICKLE2,KLF9,RRAS2,TNFRSF11A,DLGAP1,MICAL2,RAB3B,LRRIQ1,CRIM1,ESRRG,GRID1,FERMT2,ZFPM2,PALLD,NAALADL2,MAP1B,RERE,MKX,CTIF,EBF1,ADAMTS17,DPY19L2,DDAH1,ICA1,DOCK7,FBN1,MPP7,L3MBTL4,THSD7B,ZNF808,KIF21A,KIF1B,MMP16,CACNA2D1 |
| 1.678e-32 | -73.16 | carcinoid-endocrine_tumour | COSMIC cancer mutations | carcinoid-endocrine_tumour | 7964 | 1009 | 17385 | 1698 |
ARHGAP26,FLVCR2,AASS,CNTNAP3,PRSS12,RECK,DNAJC3,TUBE1,NPM1,STAT5B,CEBPA,CADM2,BCAN,NHP2,DOCK3,KIAA1217,SNX9,CA8,NOS1AP,SKI,PCDH7,TXNDC5,BAG3,FBXO32,TGFBR3,DNAH6,PPFIA2,FAAH2,RAP2A,PPP2R2B,COG3,CPE,TSHR,MEIS2,DCC,TGFA,CAP2,DSTN,LRRK2,ELMOD1,FEZ1,PRKAR2B,ABCC2,KCND3,F12,MFSD6,CA13,ENPP1,ZNF266,ATP7B,MAP9,ADRB1,ARHGAP28,ERCC5,INPP5F,TMOD2,DNHD1,TMEFF2,CRYL1,GNG12,LATS2,TMEM63C,CYP2J2,TJP1,SLC36A4,CHN1,BNIP1,FRY,KIAA1671,BACE2,APLF,FAM189A1,PRELID2,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,ST8SIA1,DENND1C,FIGN,NCAM1,MOXD1,JAM2,AGL,GLIS1,STXBP1,TSPAN9,FMNL2,LRP12,BDNF,SLC37A1,PNP,KCNQ3,MYO10,STAT4,SPATA6,ARID5B,FASN,FHL2,RYR2,HIP1,CALCRL,SMARCD3,C1R,AIG1,ST6GALNAC3,ZBBX,SNAP25,TAF4B,ARRDC4,MBNL2,SPATA7,DHX32,CACHD1,TMCO3,RIMKLB,GSTO2,SH3GL2,ADAMTS3,EMILIN2,CLMN,LAPTM4B,FBXO27,CDH2,DOCK9,MTG1,TFCP2L1,BTC,DNM3,ZNF516,GALNT12,GALNT6,LRRCC1,RGS20,BEGAIN,PKP2,IL13RA1,GRK6,COLEC10,LCP2,TXNRD3,CDS1,EPB41L3,KMO,CNKSR3,COL25A1,ALDH1L1,RTKN2,RAB27B,JAKMIP3,DNAH5,MYT1,SNX10,KCNB2,ANKRD18B,DOCK8,SCN3A,C3orf67,DZANK1,MYLK3,GARS,COL6A2,GAPDH,RNF145,NECAB1,PFKFB2,KCNH5,ADCY1,RAB38,TTC28,DSP,ASPH,METAP1D,FGFR1,GABARAPL1,SLC39A14,IRS2,IQCK,ARHGAP21,IQCH,GYPC,PDLIM3,PEMT,WWTR1,LAMB1,INPP4B,PLEKHG1,P4HA1,ALG11,FAM149A,DBP,LRRC27,RAB30,CCDC148,FARP1,TMEM132C,ANKRD13B,WDR17,ROBO2,FZD8,CD276,BACE1,IPO5,UBAC2,NKAIN2,PSD3,CREB5,PKN1,EPHB1,KCNC4,TSPAN17,COL27A1,NEO1,GHR,MYO6,C15orf41,MED12L,FES,TRPM4,PDLIM7,MN1,BCL7A,LCA5,RAB6B,CLYBL,MCF2L2,RAPGEF2,AK4,RASA3,ATP11A,SNTB1,HEG1,PTPRC,TRIB3,NSD1,PLOD2,AKT3,GNAO1,SRD5A3,OSBPL5,SLCO5A1,NEK11,HK1,DOCK6,ATP2B4,DCBLD1,CRISPLD1,BTRC,PHC1,TLL2,PHACTR3,CACNG3,LMCD1,ASS1,LILRB1,ITPR2,FAM13A,NUP62CL,NOVA1,FSTL5,PLS3,ANKRD42,RND2,RUFY4,CPNE2,FKBP9,RPS6KA2,TM9SF2,CPVL,SEC16B,KCNN2,HPS1,MARVELD2,ITGB3,TMEM143,MPPED2,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TMEM132E,ENO1,TLR4,NEB,ITGB7,SLC3A2,MARK1,KCNIP3,ABCC4,COL4A3,SPOCD1,ANK2,GDPD1,CR2,PLEKHA1,TCERG1L,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,MAP2,P4HA2,TECPR2,ERN1,CCDC146,PIK3C2B,MLLT3,TC2N,HS6ST3,RRAGD,PRKAA2,KCNV1,STXBP5L,UBASH3B,SETBP1,SORBS3,MLC1,IL18R1,PGAP1,DOK5,FHOD3,EFEMP1,NUMBL,KIAA1958,KIAA0895,ZBTB38,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,FRAS1,GAN,LRP6,ADCY6,BNIP3,SLCO4C1,FAR2,NIPAL2,FBXL2,PAK1,FGFR4,CHSY3,DPYSL5,UNC5C,BTNL9,SLC27A2,RNF170,EFNA3,GPSM1,TMTC4,TCEA3,WDR25,STRADB,OBSCN,PDE8A,SDK1,KHDRBS2,TEX9,BAIAP2,NEGR1,TBC1D2,MAPKAPK2,GRIK4,ATPAF2,PLD1,SEMA3A,RNF122,TESC,PANK3,MME,CFH,AKAP5,DOCK1,LPCAT2,XYLT1,RHPN2,NTRK3,KIF21B,LPIN3,FAM110B,RADIL,SEMA6A,CBLN1,PCLO,DDX60L,TBC1D19,FAM131B,ZNF362,TACC2,ZDHHC6,MYO3B,EEPD1,MYH15,CLVS2,SCN2A,FAM78B,TMEM56,CTH,INTU,TMEM67,EVL,UROS,TMEM65,LRRC8B,THSD4,PRDM13,FGF12,RNF125,RARRES2,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTPRJ,RNF217,PTK7,ITGA2,ABI3,KCNG1,PTPRS,MAOA,HGF,MBOAT2,CTNND2,CNTN1,TENM1,PCDH18,DYRK3,NECAB2,IL32,BMPR2,GRB14,RUSC2,MCTP2,GABRG2,USP30,PPP2R3A,ARHGAP44,SLC35F1,TTC1,TECPR1,MAP1A,GTF2F2,TSC22D1,SGK1,PRICKLE2,TSPAN13,KIAA0408,SH3PXD2B,SYK,KIAA1211,ATP2B1,DLGAP1,PPP1R3D,MICAL2,CRIP2,NUAK2,FERMT2,FNDC3A,PALLD,EXOG,ILDR2,SMPDL3B,MKX,EBF1,DDAH1,DOCK7,FAT4,FBN1,L3MBTL4,FMO4,ZNF808,PAX9,SLC1A5,TBC1D4,PTGES,KIF1B,FILIP1,CACNA2D1,C2orf27A,FAM171B,MYCBP2,PLBD2,PPP4R4,ACVR1,LGR4,SIDT1,TCP11L2,ATP8A1,VAMP8,PPFIBP2,GATA3,ENAH,PRKCA,AARS,DACH2,SLC9A7,NCS1,STK24,HECTD2,TRPS1,TYMP,ZFYVE28,FAM168A,CFHR1,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,GLDC,TBC1D8,ERGIC1,EML6,DCDC1,ACVR1C,NR6A1,KLHL3,KLHL4,ALDH1L2,DNAJC6,LRMP,DEPTOR,SLC25A28,EFHC1,TNS1,ACVR2B,SAV1,ZDHHC14,ARHGEF26,GPC6,GNAI1,AHRR,SFXN1,SH3RF1,ENPP6,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,SEMA3C,MAPK13,SERPINI1,NRP1,TANC2,UNC5B,SPOCK3,EFNB2,LRFN5,KLF8,MRC2,INPPL1,FAM124A,CELSR1,EHHADH,ALOX5AP,ZHX3,TBC1D1,SCN8A,ST6GAL1,GABRB2,DHCR24,OLAH,SLC25A27,OPHN1,GTF2IRD1,LRRC49,ISYNA1,SLC1A3,WDFY4,APBA1,TNFRSF19,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,MTUS1,MCOLN2,IL17D,ABLIM1,NAV1,SLC7A11,RALGPS2,KIAA1257,NOVA2,ADCK1,PIK3AP1,MYC,C1QL4,RUNDC3B,PRKG1,OPN3,SREBF1,CPXM2,GRIP1,SLC16A9,SAMD13,FAM155A,PRR16,GPR161,EPB41L5,PTCH2,QSOX1,TBC1D8B,SLC36A1,COL4A4,TCF24,RAPGEF4,PACSIN3,TTYH2,PEX5L,CCDC85A,CDC42BPA,PLCB1,ZNF558,MMP15,XKR9,PLEKHH2,PMEPA1,PKN3,ISM1,PELI2,THBS4,C1orf21,LRRIQ3,MPP2,SFMBT1,ANKRD20A5P,ACSM3,FRMPD3,EPHA3,PLA2G4A,TBKBP1,TCTN2,ELOVL4,RASAL2,RNF144A,RHOD,GPR65,MSR1,PLXNA2,CHUK,SPATS2L,TMEM170B,DDR1,COL14A1,TBC1D30,ZFYVE9,TIAM2,TMEM53,ZNF827,SPEG,SHF,NAP1L3,ATP6AP1L,GAB2,TRDMT1,PDK1,TMEM43,SHANK2,PREX1,NLGN4X,SATB2,PRKCQ,PYGO1,ATP1B1,TBC1D16,ATP10D,SNCA,ISG20,HTR7,IKZF3,PRKCB,TDO2,CCNA1,ZNF704,HPGD,GRB10,BMPR1A,HS3ST3B1,ATG5,CTTNBP2,NR3C2,COBL,PURG,STON2,MID1,HACE1,DENND5B,WASF3,ANO10,MYO1D,MXI1,PLSCR4,ATP9A,EPS8,CCNJL,HERC5,GPR180,TPD52L1,INPP1,NEDD4,RASSF8,RGS17,LRRC55,SOAT2,GPR155,SGK3,RALGAPA2,SLC6A15,DYNC2H1,FIG4,TBC1D9,SMAD6,B4GALT6,TMC7,VAV3,ARHGEF28,GSTM2,ARAP2,SYNPO2,AGPAT4,CACNA1E,MPP1,PTPN13,ZDHHC15,UCHL3,GUCY1A2,SKAP1,GPR137C,ZIC1,FGR,TERT,PLXDC2,MCC,PGM2L1,TUFT1,SVIL,GRIN2D,MYOM2,CERS1,LARP1,OCLN,SLC43A1,ATP1A3,EXPH5,ACSL1,UGT8,KIF5A,HEBP1,PTPN21,C20orf194,ANKRD18A,ABAT,IKZF2,DNER,CACNB4,SLCO3A1,HMCN1,CEP85L,F3,RTN1,ARHGEF10L,ADPRHL1,LGI2,CYP51A1,PPM1E,SIPA1L2,LRRC6,AKAP7,SLC10A7,ANKFN1,POF1B,TRPC1,SLC2A12,PCOLCE2,PTPRE,MYRIP,FANK1,SLIT2,RASGRP1,PDGFRB,PRKACB,LAMP3,TNK2,ATL1,GPM6A,SESN2,SKAP2,CAPN5,JPH1,ZNF565,ROR1,COTL1,SGK2,SERGEF,EML1,TMEM132B,GSN,AK1,HPSE,ITGBL1,NCAM2,FAM114A2,NCOA7,TNFSF4,PPARGC1A,APBA2,MAGI2,FRMD5,PCSK5,GPT2,UST,BCL11B,SV2B,MOCOS,ZNF395,FN1,RHOBTB1,SEC24D,BVES,STXBP6,ELOVL7,CYP4V2,YPEL2,LAMC3,CHADL,GALNT13,CHSY1,FAM81A,PHGDH,SATB1,CD7,DDIT4,ZNF354A,SLC30A4,EEF2,EBF4,FAM107B,LIMCH1,LRP3,NOS3,CDH26,GPR176,PCDH10,ANKRD20A2,PODXL2,SDC3,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,TMEM154,CSAG1,KIAA0355,FCHO2,NCR3LG1,FAT1,HK2,RAI14,RAB31,SH3BP4,TMEM117,PTPRN2,XKR4,DIRC2,CREB3L2,DMXL2,EML5,ZSWIM5,NEK10,CELSR3,PLEKHA5,PSTPIP2,HECW2,COL18A1,COBLL1,TDRKH,CANX,PIBF1,UBTD2,DOCK2,SP8,SCIN,COL22A1,PDZD8,UNC13B,KAZN,RPS6KL1,REEP1,ZNF521,MAP7,ACVR2A,FHIT,GULP1,PROS1,MDH1B,WWC2,MET,TMEM120B,DPP10,ANTXR2,FER,PTPRU,SLC39A8,TES,TTLL7,DOCK5,C1orf174,CENPV,TPK1,WARS,BCL11A,ARMC4,ZNF93,LMLN,KPNA3,BACH2,RBPMS2,EIF4EBP1,TMPRSS9,DUSP19,SOHLH2,DISP1,RNF130,LIFR,PSPH,MAST1,TNIK,PRSS16,ARHGEF11,CLGN,TSPAN15,REL,CMTM8,LRP4,TNFSF13B,NSUN6,CLSTN2,COL4A5,IGF2BP2,FAM174B,SEL1L3,BMP6,MCU,RAB11FIP5,FSD1,CHN2,PRKCD,STC2,EHD3,DSG2,KIAA0319,ACTA2,TRIM3,AFAP1L2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,RBMS2,RAB3B,USP2,HNF4G,CRIM1,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,ASAP3,MEI1,PRRG1,MARS,PHACTR2,C3orf70,ZFPM2,GALNT14,NAALADL2,MAP1B,RERE,CTIF,ADAMTS17,DPY19L2,ICA1,EDA,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,UACA,KIAA0513,KIF21A,MMP16,MAP3K20,SLC16A10,ABCG1 |
| 1.022e-30 | -69.06 | pancreas-carcinoid-endocrine_tumour | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour | 7455 | 952 | 17385 | 1698 |
ARHGAP26,FLVCR2,AASS,CNTNAP3,PRSS12,RECK,DNAJC3,TUBE1,NPM1,STAT5B,CADM2,BCAN,NHP2,DOCK3,KIAA1217,SNX9,CA8,NOS1AP,SKI,PCDH7,TXNDC5,BAG3,FBXO32,TGFBR3,DNAH6,PPFIA2,FAAH2,RAP2A,PPP2R2B,COG3,CPE,TSHR,MEIS2,DCC,TGFA,CAP2,DSTN,ELMOD1,FEZ1,PRKAR2B,ABCC2,KCND3,F12,MFSD6,CA13,ENPP1,ZNF266,ATP7B,MAP9,ARHGAP28,ERCC5,INPP5F,TMOD2,DNHD1,TMEFF2,CRYL1,GNG12,TMEM63C,CYP2J2,TJP1,SLC36A4,CHN1,BNIP1,FRY,KIAA1671,BACE2,APLF,FAM189A1,PRELID2,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,ST8SIA1,DENND1C,FIGN,NCAM1,MOXD1,JAM2,AGL,GLIS1,STXBP1,TSPAN9,FMNL2,LRP12,BDNF,SLC37A1,PNP,KCNQ3,MYO10,STAT4,SPATA6,ARID5B,FASN,FHL2,RYR2,HIP1,CALCRL,SMARCD3,AIG1,ST6GALNAC3,ZBBX,SNAP25,TAF4B,ARRDC4,MBNL2,SPATA7,DHX32,CACHD1,TMCO3,RIMKLB,GSTO2,SH3GL2,ADAMTS3,EMILIN2,CLMN,LAPTM4B,FBXO27,CDH2,DOCK9,MTG1,TFCP2L1,BTC,DNM3,ZNF516,GALNT12,GALNT6,LRRCC1,RGS20,BEGAIN,PKP2,IL13RA1,COLEC10,LCP2,TXNRD3,CDS1,EPB41L3,KMO,CNKSR3,COL25A1,ALDH1L1,RTKN2,RAB27B,JAKMIP3,DNAH5,MYT1,SNX10,KCNB2,ANKRD18B,SCN3A,C3orf67,DZANK1,MYLK3,GARS,COL6A2,GAPDH,RNF145,NECAB1,PFKFB2,KCNH5,ADCY1,RAB38,TTC28,DSP,ASPH,METAP1D,FGFR1,GABARAPL1,SLC39A14,IRS2,IQCK,ARHGAP21,IQCH,GYPC,PDLIM3,PEMT,WWTR1,LAMB1,INPP4B,PLEKHG1,P4HA1,ALG11,FAM149A,DBP,LRRC27,RAB30,CCDC148,FARP1,ANKRD13B,WDR17,ROBO2,FZD8,CD276,BACE1,IPO5,UBAC2,NKAIN2,PSD3,CREB5,KCNC4,TSPAN17,COL27A1,NEO1,GHR,MYO6,C15orf41,MED12L,TRPM4,PDLIM7,MN1,BCL7A,LCA5,RAB6B,CLYBL,MCF2L2,RAPGEF2,AK4,RASA3,ATP11A,SNTB1,HEG1,PTPRC,TRIB3,NSD1,PLOD2,GNAO1,SRD5A3,OSBPL5,SLCO5A1,NEK11,HK1,DOCK6,ATP2B4,DCBLD1,CRISPLD1,BTRC,PHC1,TLL2,PHACTR3,CACNG3,LMCD1,ASS1,LILRB1,ITPR2,FAM13A,NUP62CL,NOVA1,FSTL5,PLS3,ANKRD42,RND2,RUFY4,CPNE2,FKBP9,TM9SF2,CPVL,SEC16B,KCNN2,HPS1,ITGB3,TMEM143,MPPED2,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TMEM132E,ENO1,TLR4,NEB,ITGB7,SLC3A2,MARK1,KCNIP3,ABCC4,COL4A3,SPOCD1,ANK2,GDPD1,CR2,PLEKHA1,TCERG1L,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,MAP2,P4HA2,TECPR2,CCDC146,PIK3C2B,MLLT3,TC2N,HS6ST3,RRAGD,KCNV1,STXBP5L,UBASH3B,SETBP1,SORBS3,MLC1,IL18R1,PGAP1,DOK5,FHOD3,EFEMP1,NUMBL,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,FRAS1,GAN,LRP6,ADCY6,BNIP3,SLCO4C1,FAR2,NIPAL2,FBXL2,CHSY3,DPYSL5,UNC5C,BTNL9,SLC27A2,RNF170,EFNA3,GPSM1,TMTC4,TCEA3,WDR25,OBSCN,PDE8A,SDK1,KHDRBS2,TEX9,BAIAP2,NEGR1,TBC1D2,GRIK4,ATPAF2,PLD1,SEMA3A,RNF122,PANK3,TESC,MME,CFH,AKAP5,DOCK1,LPCAT2,XYLT1,RHPN2,NTRK3,KIF21B,FAM110B,RADIL,SEMA6A,CBLN1,PCLO,DDX60L,TBC1D19,FAM131B,ZNF362,TACC2,ZDHHC6,EEPD1,MYH15,CLVS2,SCN2A,FAM78B,TMEM56,CTH,INTU,TMEM67,EVL,UROS,TMEM65,LRRC8B,THSD4,PRDM13,FGF12,RNF125,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTPRJ,RNF217,PTK7,ITGA2,ABI3,KCNG1,PTPRS,MAOA,HGF,MBOAT2,CTNND2,CNTN1,TENM1,PCDH18,NECAB2,BMPR2,GRB14,RUSC2,MCTP2,GABRG2,USP30,PPP2R3A,ARHGAP44,SLC35F1,TTC1,TECPR1,GTF2F2,TSC22D1,PRICKLE2,TSPAN13,KIAA0408,SH3PXD2B,KIAA1211,ATP2B1,DLGAP1,PPP1R3D,MICAL2,CRIP2,FERMT2,FNDC3A,PALLD,EXOG,ILDR2,SMPDL3B,MKX,EBF1,DDAH1,DOCK7,FAT4,FBN1,L3MBTL4,FMO4,ZNF808,PAX9,SLC1A5,TBC1D4,PTGES,KIF1B,FILIP1,CACNA2D1,C2orf27A,FAM171B,MYCBP2,PLBD2,PPP4R4,ACVR1,LGR4,SIDT1,TCP11L2,ATP8A1,VAMP8,PPFIBP2,GATA3,ENAH,PRKCA,AARS,DACH2,SLC9A7,NCS1,STK24,HECTD2,ZFYVE28,FAM168A,CFHR1,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,GLDC,ERGIC1,EML6,DCDC1,ACVR1C,NR6A1,KLHL3,KLHL4,ALDH1L2,DNAJC6,LRMP,DEPTOR,SLC25A28,TNS1,EFHC1,SAV1,ZDHHC14,ARHGEF26,GPC6,GNAI1,AHRR,SFXN1,SH3RF1,ENPP6,NCKAP1L,ENTPD7,RASGRF2,CCBE1,SEMA3C,SERPINI1,NRP1,TANC2,UNC5B,SPOCK3,EFNB2,LRFN5,KLF8,MRC2,INPPL1,FAM124A,CELSR1,EHHADH,ALOX5AP,ZHX3,TBC1D1,SCN8A,ST6GAL1,GABRB2,DHCR24,OLAH,SLC25A27,OPHN1,GTF2IRD1,LRRC49,ISYNA1,SLC1A3,WDFY4,APBA1,TNFRSF19,ADSSL1,DYNC1I1,RPL13A,MTUS1,MCOLN2,IL17D,ABLIM1,NAV1,SLC7A11,RALGPS2,KIAA1257,NOVA2,PIK3AP1,C1QL4,RUNDC3B,OPN3,SREBF1,PRKG1,CPXM2,GRIP1,SLC16A9,SAMD13,PRR16,FAM155A,GPR161,EPB41L5,PTCH2,QSOX1,TBC1D8B,SLC36A1,COL4A4,TCF24,RAPGEF4,PACSIN3,TTYH2,PEX5L,CCDC85A,PLCB1,ZNF558,MMP15,XKR9,PLEKHH2,PMEPA1,PKN3,ISM1,PELI2,THBS4,C1orf21,LRRIQ3,MPP2,SFMBT1,ANKRD20A5P,ACSM3,FRMPD3,EPHA3,PLA2G4A,TBKBP1,TCTN2,ELOVL4,RASAL2,RNF144A,RHOD,GPR65,PLXNA2,MSR1,CHUK,SPATS2L,TMEM170B,COL14A1,TBC1D30,ZFYVE9,TIAM2,TMEM53,ZNF827,SHF,NAP1L3,ATP6AP1L,GAB2,TRDMT1,PDK1,TMEM43,SHANK2,PREX1,NLGN4X,SATB2,PRKCQ,PYGO1,ATP1B1,TBC1D16,ATP10D,SNCA,ISG20,HTR7,IKZF3,PRKCB,TDO2,CCNA1,ZNF704,HPGD,GRB10,HS3ST3B1,ATG5,CTTNBP2,NR3C2,COBL,PURG,STON2,MID1,HACE1,DENND5B,ANO10,WASF3,MYO1D,MXI1,PLSCR4,ATP9A,EPS8,CCNJL,HERC5,GPR180,TPD52L1,INPP1,NEDD4,RASSF8,RGS17,LRRC55,SOAT2,GPR155,RALGAPA2,SLC6A15,DYNC2H1,FIG4,TBC1D9,SMAD6,B4GALT6,TMC7,VAV3,ARHGEF28,GSTM2,ARAP2,SYNPO2,AGPAT4,CACNA1E,MPP1,PTPN13,ZDHHC15,UCHL3,GUCY1A2,SKAP1,GPR137C,ZIC1,TERT,PLXDC2,PGM2L1,TUFT1,SVIL,GRIN2D,MYOM2,CERS1,LARP1,OCLN,SLC43A1,ATP1A3,EXPH5,ACSL1,UGT8,KIF5A,HEBP1,PTPN21,C20orf194,ANKRD18A,ABAT,IKZF2,DNER,CACNB4,SLCO3A1,HMCN1,CEP85L,F3,RTN1,ARHGEF10L,ADPRHL1,LGI2,CYP51A1,PPM1E,SIPA1L2,LRRC6,AKAP7,SLC10A7,ANKFN1,POF1B,TRPC1,SLC2A12,PCOLCE2,PTPRE,MYRIP,FANK1,SLIT2,RASGRP1,LAMP3,TNK2,ATL1,GPM6A,SESN2,SKAP2,CAPN5,JPH1,ZNF565,ROR1,COTL1,SGK2,SERGEF,EML1,TMEM132B,GSN,AK1,HPSE,ITGBL1,NCAM2,FAM114A2,NCOA7,TNFSF4,PPARGC1A,APBA2,MAGI2,FRMD5,PCSK5,GPT2,UST,BCL11B,SV2B,MOCOS,ZNF395,RHOBTB1,SEC24D,BVES,STXBP6,ELOVL7,CYP4V2,YPEL2,LAMC3,CHADL,GALNT13,CHSY1,FAM81A,PHGDH,SATB1,CD7,ZNF354A,SLC30A4,EEF2,EBF4,FAM107B,LIMCH1,LRP3,NOS3,CDH26,GPR176,PCDH10,ANKRD20A2,PODXL2,SDC3,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,TMEM154,KIAA0355,FCHO2,CSAG1,NCR3LG1,FAT1,HK2,RAI14,RAB31,SH3BP4,TMEM117,PTPRN2,XKR4,DIRC2,CREB3L2,DMXL2,EML5,ZSWIM5,NEK10,CELSR3,PLEKHA5,PSTPIP2,HECW2,COL18A1,COBLL1,CANX,PIBF1,UBTD2,DOCK2,SP8,SCIN,COL22A1,PDZD8,UNC13B,KAZN,REEP1,ZNF521,MAP7,ACVR2A,FHIT,GULP1,PROS1,MDH1B,WWC2,MET,TMEM120B,DPP10,ANTXR2,FER,PTPRU,SLC39A8,TES,TTLL7,DOCK5,CENPV,TPK1,WARS,BCL11A,ARMC4,ZNF93,LMLN,KPNA3,BACH2,RBPMS2,EIF4EBP1,TMPRSS9,DUSP19,SOHLH2,DISP1,RNF130,LIFR,PSPH,PRSS16,ARHGEF11,CLGN,TSPAN15,REL,CMTM8,LRP4,TNFSF13B,NSUN6,CLSTN2,IGF2BP2,FAM174B,SEL1L3,BMP6,MCU,RAB11FIP5,FSD1,CHN2,PRKCD,STC2,EHD3,DSG2,KIAA0319,ACTA2,TRIM3,AFAP1L2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,RBMS2,RAB3B,USP2,HNF4G,CRIM1,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,ASAP3,MEI1,PRRG1,MARS,PHACTR2,C3orf70,ZFPM2,GALNT14,NAALADL2,MAP1B,RERE,CTIF,ADAMTS17,DPY19L2,ICA1,EDA,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,MMP16,MAP3K20,SLC16A10,ABCG1 |
| 4.192e-30 | -67.64 | prostate-carcinoma | COSMIC cancer mutations | prostate-carcinoma | 9227 | 1121 | 17385 | 1698 |
ARHGAP26,THOC5,ADAL,GRIK2,CNTNAP3,MCOLN3,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,DCC,EXOC6B,LRRK2,NFIA,PRKAR2B,ABCC2,FGF17,PYCR1,ENPP1,ATP7B,MAP9,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,FOXG1,BBS9,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,ALPK1,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,C11orf45,CACHD1,TEX15,RIMKLB,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,TFCP2L1,GRK6,TLR3,ALDH1L1,RPL26L1,DNAH5,ZNF365,MYT1,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,NECAB1,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,ENTPD1,ARHGAP21,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,WDR17,FZD8,CD276,PLAG1,UBAC2,PSD3,EPHB1,ZNF219,LRRN1,PCBP4,GHR,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,MN1,RAB6B,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,TLL2,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,ITGB3,MPPED2,JAKMIP2,TMEM132E,PGBD5,DBN1,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,CR2,TTC22,SESN1,CRYBG3,SPNS1,TRIM9,TCF7L1,INSIG1,KLF12,HS6ST3,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,DOK5,FHOD3,NUMBL,GALNT1,ZBTB38,FRAS1,SMTN,LRP6,FAR2,VGLL4,NDUFA4L2,DPYSL5,EFNA3,STRADB,MAFB,OBSCN,SLITRK5,SDK1,KHDRBS2,NEGR1,TBC1D2,GRIK4,SLC2A6,PLD1,SEMA3A,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,DDX60L,IDI1,TACC2,BCL6,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,HRASLS,INTU,TMEM65,LRRC8B,PRDM13,ACO1,RNF125,PTPRJ,RNF217,PTPRS,MAOA,MBOAT2,CTNND2,HEY1,NECAB2,BMPR2,MCTP2,RASD1,USP30,SLC35F1,FOXP2,TTC1,GTF2F2,TSC22D1,SGK1,TSPAN13,SYK,ATP2B1,DUSP1,LRRIQ1,FOXN3,FERMT2,PALLD,EXOG,MGMT,DKK1,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,KIF1B,CACNA2D1,ZNF235,FAM171B,LGR4,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,KCNS3,GLDC,ERGIC1,ACVR1C,WISP3,LRMP,BNIP3L,ZDHHC14,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SPRY4,NRP1,SPOCK3,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,DHCR24,LRRC49,APBA1,TNFRSF19,MTUS1,ABLIM1,RALGPS2,SLC7A11,ADCK1,MYC,PRKG1,CPXM2,GRIP1,FAM155A,PRR16,GPR161,PTCH2,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,CECR2,C1orf21,LRRIQ3,MPP2,SQLE,SFMBT1,SLFN5,SMYD3,NBL1,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ZNF438,SHF,PDE4D,GATM,GAB2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,PYGO1,ATP1B1,ATP10D,IKZF3,ZNF704,HPGD,BMPR1A,COBL,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,TMC7,VAV3,SLC40A1,ALDH2,SH3BP2,PXN,AGPAT4,PTPN13,RPL21,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,LARP1,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,SLC2A13,HMCN1,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SKAP2,YAP1,COTL1,SGK2,GPRC5B,HPSE,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHSY1,FAM81A,SPINK5,RNF141,EEF2,SLC30A4,LIMCH1,CAND2,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,SDC3,SLC46A3,STEAP1,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,OSBPL6,XKR4,DMXL2,SORBS1,ARHGAP22,HECW2,COBLL1,CANX,PIBF1,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,ACVR2A,FHIT,TMEM120B,PRAME,PTPRU,PTPN6,C3orf52,CD40,BATF3,BCL11A,ARMC4,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RNF130,MAST1,ARHGEF11,TSPAN15,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,SEL1L3,MCU,RAB11FIP5,FSD1,KCNJ4,PRKCD,STC2,CCDC122,AFAP1L2,IPCEF1,RBMS2,CARD6,USP2,HNF4G,CRIM1,SYBU,GALNT14,TLR6,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,EDA,RND3,ACER2,UACA,RNF157,NPHP1,ABCG1,GXYLT2,PDE1B,PRSS12,AASS,LSM11,DNAJC3,CADM2,STAT5B,CA8,NOS1AP,EPDR1,PCDH7,BAG3,TGFBR3,FBXO32,PMAIP1,DNAH6,PPFIA2,TSHR,NKX2-1,MEIS2,CAP2,TGFA,WLS,ELMOD1,MSRB3,MFSD6,ALDOA,ZBTB20,TMEFF2,MEF2C,CRYL1,LPP,CARS,LATS2,GNG12,SLC36A4,SYCP2,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,NCAM1,TSPAN9,GLIS1,AGL,GFRA1,FMNL2,CHRM3,BDNF,MYO10,MGST3,STAT4,CALCRL,SMARCD3,RYR2,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,TRPC3,CSRP2,BTC,ZNF516,DNM3,GALNT6,FAM131C,LRRCC1,BEGAIN,PKP2,IL13RA1,NRXN1,COLEC10,CDS1,EPB41L3,RNF150,GPRIN1,CHRNA5,KMO,CNKSR3,COL25A1,DACT1,RTKN2,JAKMIP3,ARL4D,SCN3A,DOCK8,PERP,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,FGFR1,METAP1D,IRS2,IQCK,IQCH,GYPC,PEMT,WWTR1,INPP4B,PLEKHG1,PAM,PLD5,KLHL31,HOXB9,TMEM132C,FARP1,ROBO2,C1QTNF3,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,COL27A1,NEO1,GAS2L3,NPTXR,MYO6,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,SNTB1,PTPRC,GALNT3,PLPPR2,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,DOCK6,BTRC,FOXA1,NMNAT3,TRIM2,SYT12,FHDC1,LILRB1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,LIN7A,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,SLC3A2,ABCC4,GDPD1,PLEKHA1,TCERG1L,NT5DC2,PLEKHB1,INHBC,MAP2,GNB4,P4HA2,CCDC146,TECPR2,TNFRSF1A,PIK3C2B,MLLT3,PRKAA2,UBASH3B,RASL11B,SETBP1,MLC1,PGAP1,IL18R1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,KIAA0895,SEMA4F,IGF1R,ABCA5,GATA2,PDE10A,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,UNC5C,MID2,SLC27A2,SPATA13,TMTC4,PPFIA4,WDR25,PDE8A,TEX9,MAPKAPK2,ATPAF2,CSF1,MFSD2A,PANK3,TESC,SFN,SIX2,MME,CFH,LPCAT2,RBFOX2,XYLT1,RNF24,LPIN3,SEZ6L2,PCLO,FAM131B,TBC1D19,ZDHHC6,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,THSD4,FGF12,GSTO1,FBXO36,JAM3,SMAD3,RANBP2,NRG3,PTK7,ITGA2,SEPT5,TTC39A,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,RUSC2,APBB1,SELL,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,NUAK2,TGDS,FNDC3A,NPDC1,FAT4,L3MBTL4,ZNF214,FMO4,DLG2,TBC1D4,FILIP1,C2orf27A,CGN,MYCBP2,ACVR1,PPP4R4,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,ENAH,ADAMTS6,DACH2,AARS,STK24,NCS1,SLC22A18,FAM168A,CHRDL1,ATRNL1,BEND4,SP140,VWA5A,PACSIN1,MAGEA6,PLTP,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,TNS1,SLC25A28,ACVR2B,SAV1,GPC6,AHRR,NCKAP1L,PLK2,RASGRF2,ENTPD7,CCBE1,SEMA3C,UNC5B,TANC2,INPPL1,EHHADH,CELSR1,ALOX5AP,ZHX3,PTPRD,GABRB2,SCN8A,OPHN1,GTF2IRD1,WDFY4,SLC1A3,DYNC1I1,ADSSL1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,PRELID1,RUNDC3B,SLC16A9,TSPAN12,MPDZ,RIMS2,IGSF3,EPB41L5,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,XKR9,PKN3,PMEPA1,IQSEC2,ACSM3,PLA2G4A,EPHA3,AMOTL1,RASAL2,ELOVL4,RNF144A,GPR65,OTX1,CHUK,SPATS2L,ZNF827,NELL2,NBEA,SCRN1,DAB2IP,NAP1L3,SERPINH1,VNN2,PDK1,TMEM43,SOX21,PRKCQ,TBC1D16,HTR7,PRKCB,KLF5,GRB10,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,ANO10,WASF3,GLIPR1L1,ATP9A,RGS7,GDPD5,NEDD4,RGS17,SGK3,SLC6A15,FIG4,SEPT3,SPRY2,ARAP2,SYNPO2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,CLDN12,TUFT1,MYOM2,GRIN2D,OCLN,ATP1A3,EXPH5,MVK,KIF5A,ANKRD18A,CACNB4,DNER,ABHD4,KREMEN1,SLCO3A1,CEP85L,CYP51A1,ARHGEF10L,RTN1,LRRC6,AKAP7,SLC10A7,PCOLCE2,PTPRE,OR2W3,FANK1,SLIT2,PRKACB,RASGRP1,GPM6A,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,APBA2,BCL11B,UST,FN1,SEC24D,JDP2,ELOVL7,LAMC3,ATP6V1E2,GALNT13,SATB1,DDIT4,OTUD1,FAM107B,EBF4,NCEH1,NOS3,IL17RD,RAX,GPR176,PARD3B,EDEM3,DUSP9,WWC1,LHPP,B4GALNT3,GLCE,RAI14,HK2,EGFL7,DIRC2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,MORC4,DOCK2,SP8,COL22A1,UNC13B,RPS6KL1,ZNF521,MAP7,GULP1,POU2F2,MET,WWC2,HSPA2,SUSD3,DPP10,PHLDB2,FER,TES,DOCK5,TPK1,MSC,LMLN,BACH2,DISP1,LIFR,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,RIN2,MSX1,RAB3B,ESRRG,NR4A1,CYTH3,GRID1,OGDHL,MEI1,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,RERE,MAP1B,GPR37,ADAMTS17,MPP7,MAP2K6,PRCP,THSD7B,KIF21A,GEM,MMP16,SLC16A10 |
| 7.833e-30 | -67.02 | lymphoid_neoplasm | COSMIC cancer mutations | lymphoid_neoplasm | 12607 | 1420 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,NPM1,CTBP2,CEBPA,KIAA1217,BCAN,SNX9,ABHD6,SKI,TXNDC5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,KLHL23,DCC,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,CAB39L,ERCC5,INPP5F,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,BBS9,CHN1,FRY,PAIP2B,APLF,SRGAP1,TOX,CADPS2,FAM84B,ALPK1,DENND1C,MOXD1,FIGN,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,FHL2,FASN,HIP1,ST6GALNAC3,AIG1,SHISA2,ZBBX,SNAP25,ARRDC4,SPATA7,TEX15,CACHD1,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,ALDH1L1,FAM133A,RPL26L1,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,GAPDH,COL6A2,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,ENTPD1,SLC39A14,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,BACE1,PLAG1,FZD8,CD276,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,GHR,C15orf41,ZFP36L2,MED12L,PARP9,TRPM4,B9D1,MN1,RAB6B,RASA3,AK4,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,LMCD1,ITPR2,MGAT5B,FAM13A,CCNJ,PLS3,RUFY4,RPS6KA2,TM9SF2,AADAT,SEC16B,CPVL,ITGB3,MPPED2,TMEM143,JAKMIP2,TMEM132E,ENO1,RAPGEF5,ZNF391,PGBD5,DBN1,KCNIP3,ATF4,MARK1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,FHOD3,SPIRE1,RNF180,GALNT1,NUMBL,ZBTB38,ZNF440,FRAS1,HS3ST5,GAN,LRP6,ADCY6,NIPAL2,FAR2,VGLL4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,SLITRK5,STRADB,OBSCN,SDK1,KHDRBS2,GPR19,NEGR1,TBC1D2,GRIK4,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,DDX60L,SEMA6A,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,HRASLS,IGFBP3,RPS13,INTU,CSN2,LRRC8B,TMEM65,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,TENM1,DYRK3,NECAB2,BMPR2,KLHL13,MCTP2,USP30,SLC35F1,TTC1,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,SYK,ATP2B1,DUSP1,LRRIQ1,FERMT2,PRICKLE1,EXOG,PALLD,ILDR2,MGMT,SMPDL3B,HOMER3,EBF1,CD37,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,HECTD2,SLC9A7,TRPS1,TYMP,ZFYVE28,KCNS3,SERINC2,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,KLHL3,WISP3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,DSEL,MAPK13,SERPINI1,SPRY4,NRP1,SPOCK3,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,SREBF1,PRKG1,GRIP1,CPXM2,PRR16,FAM155A,COL9A2,GPR161,BOD1,PTCH2,RPL26,VLDLR,RAPGEF4,DCHS1,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,CCDC110,MSR1,PLXNA2,TMEM170B,COL14A1,DDR1,TIAM2,ZFYVE9,SPEG,ASNS,ZNF438,SHF,PDE4D,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,ATF3,SATB2,ATP1B1,PYGO1,ATOH1,ATP10D,ISG20,SNCA,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,MID1,STON2,COBL,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,KIF5C,HERC5,NDFIP2,TPD52L1,INPP1,RASSF8,LRRC55,IRX5,GPR155,AFF2,DYNC2H1,TBC1D9,ERRFI1,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,SH3BP2,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,TMEM126A,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,CERS1,DDIT3,UGT8,ACTL8,PTPN21,C20orf194,HMCN1,CHST10,F3,LGI2,ADPRHL1,EPCAM,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,PPARGC1A,MAGI2,FRMD5,PCSK5,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,CHSY1,FAM81A,SPINK5,RNF141,EEF2,SLC30A4,ZNF354A,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,PCDH10,CDH26,PODXL2,SLITRK2,SDC3,STEAP1,HERPUD1,TMEM154,KIAA0355,FAT1,NCR3LG1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,FNBP1L,NKX2-8,OSBPL6,XKR4,DMXL2,SORBS1,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,REEP1,FABP6,ACVR2A,FHIT,PROS1,TMEM120B,SEMA6C,PRAME,ANTXR2,PTPRU,PTPN6,MVD,AMIGO1,CD40,CENPV,ZNF569,BCL11A,BATF3,CAMK2N1,ARMC4,ZNF93,KPNA3,TMPRSS9,RBPMS2,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,SSX1,FAM117B,IGF2BP2,COL4A5,OVOL2,FAM174B,SEL1L3,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,CADM2,STAT5B,CHAC1,DOCK3,CA8,NOS1AP,EYA4,PCDH7,EPDR1,BAG3,TGFBR3,FBXO32,DNAH6,FAAH2,PPFIA2,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,TGFA,GJB2,CAP2,WLS,ELMOD1,MSRB3,F12,MFSD6,CA13,ARHGAP28,ZBTB20,TMEFF2,CRYL1,MEF2C,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,FMNL2,GFRA1,CHRM3,LRP12,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,CALCRL,SMARCD3,RYR2,PLS1,C1R,TAF4B,OR11H4,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,FBXO27,TRPC3,BTC,NUDT10,DNM3,ZNF516,TMSB15A,GALNT12,GALNT6,MYO1B,BEGAIN,RGS20,PKP2,IL13RA1,LCP2,NRXN1,COLEC10,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,GPRIN1,CHRNA5,KMO,COL25A1,CNKSR3,RTKN2,JAKMIP3,ARL4D,FAM155B,SCN3A,DOCK8,DZANK1,SSH3,RNF145,KCNH5,NKX3-2,NPM3,RAB38,TTC28,FGFR1,METAP1D,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,PLEKHG1,INPP4B,P4HA1,RCN3,TNFSF15,PLD5,KLHL31,HOXB9,TMEM132C,FARP1,ROBO2,C1QTNF3,IPO5,C1orf226,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,SNTB1,HEG1,GALNT3,PTPRC,TRIB3,ID3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,DCBLD1,FOXA1,NBPF4,SYT12,FHDC1,LILRB1,ASS1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNAB1,EOMES,KCNN2,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,SLC3A2,ABCC4,GDPD1,PLEKHA1,TCERG1L,BATF,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,ZCCHC24,UBASH3B,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,KIAA0895,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,SLC27A2,RNF170,TMTC4,TCEA3,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,HEYL,MFSD2A,PANK3,TESC,SIX2,SFN,MME,CFH,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,PCLO,CBLN1,TBC1D19,SLC22A17,ZDHHC6,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,TMEM67,UROS,THSD4,FGF12,FBXO36,PAGE5,FRK,JAM3,SMAD3,RANBP2,NRG3,GBP1,PTK7,ABI3,ITGA2,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,COL9A3,PCDH18,LPAR2,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,EIF1,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,FMO4,ZNF214,ZNF474,ZNF808,DLG2,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,CGN,MYCBP2,PPP4R4,ACVR1,PAGE1,TCP11L2,SIDT1,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,RAC3,DACH2,AARS,NCS1,STK24,SLC16A2,SLC22A18,FAM168A,CFHR1,CHRDL1,ATRNL1,GSTM3,BEND4,SP140,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,DCDC1,EML6,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,TNS1,SLC25A28,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,SFXN1,NCKAP1L,CCBE1,PLK2,RASGRF2,ENTPD7,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ZHX3,PTPRD,GABRB2,SCN8A,OLAH,OPHN1,SLC25A27,GTF2IRD1,WDFY4,ISYNA1,SLC1A3,DYNC1I1,ADSSL1,PRRG4,MECOM,MCOLN2,NAV1,KIAA1257,CNTN4,PIK3AP1,PDZD7,RUNDC3B,OPN3,SLC16A9,TSPAN12,MPDZ,SAMD13,RIMS2,IGSF3,RNF152,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTC30A,TTYH2,CCDC85A,C4orf19,PLCB1,FAM162A,ZNF558,DAGLA,XKR9,PKN3,PMEPA1,ISM1,AMPD1,ACSM3,PLA2G4A,FRMPD3,EPHA3,TBKBP1,AMOTL1,RASAL2,ELOVL4,RNF144A,ZNF311,CHUK,SPATS2L,NUDT12,TBC1D30,TMEM53,NELL2,ZNF827,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,MAP3K21,KLF5,GRB10,HS3ST3B1,ATG5,CTTNBP2,NR3C2,DENND5B,WASF3,ANO10,MXI1,ANKRD13D,GLIPR1L1,ATP9A,CCNJL,GPR180,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,PFKFB4,SYNPO2,ARAP2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,PGM2L1,TUFT1,GRIN2D,MYOM2,OCLN,ATP1A3,EXPH5,MPZL3,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,ANKRD18A,ABAT,CACNB4,RBM11,DNER,IKZF2,KREMEN1,SLCO3A1,CEP85L,QPRT,CYP51A1,ARHGEF10L,RTN1,LRRC6,AKAP7,SLC10A7,POF1B,SLC2A12,PCOLCE2,OR2W3,PTPRE,FANK1,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,APBA2,BCL11B,UST,FN1,SEC24D,JDP2,RIMKLA,ELOVL7,YPEL2,CYP4V2,ATP6V1E2,LAMC3,GALNT13,CD7,SATB1,PHGDH,OTUD1,CA2,FAM107B,EBF4,NCEH1,NOS3,ANKRD20A2,GPR176,RAX,IL17RD,PARD3B,EDEM3,WWC1,DUSP9,PRDM1,LHPP,B4GALNT3,AMDHD1,GLCE,RAI14,HK2,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,TDRKH,BCL6B,UBTD2,DOCK2,ZSCAN5A,COL22A1,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,POU2F2,MET,ZNF460,HSPA2,SUSD3,DPP10,GCA,FER,PHLDB2,SLC39A8,TES,SYNJ2BP,DOCK5,TTLL7,WARS,TPK1,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,CHN2,EHD3,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,RIN2,RAB3B,ESRRG,NR4A1,CYTH3,GRID1,OGDHL,PRRG1,MEI1,MARS,PHACTR2,AGAP2,ARHGAP32,ZFPM2,C3orf70,MAP1B,RERE,GPR37,ADAMTS17,TIFA,NACC2,MPP7,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SLC16A10,STOM,SNPH |
| 4.070e-29 | -65.37 | brainstem | COSMIC cancer mutations | brainstem | 3173 | 488 | 17385 | 1698 |
ARHGAP26,FAM171B,CGN,GXYLT2,ACVR1,TCP11L2,AASS,PRSS12,ATP8A1,DNAJC3,PPFIBP2,CTBP2,ADAMTS6,CADM2,BCAN,PRKCA,KIAA1217,SNX9,ABHD6,SLC9A7,HECTD2,SKI,TXNDC5,BAG3,DNAH6,SLC16A2,PPFIA2,CHRDL1,ATRNL1,PPP2R2B,SP140,COG3,THSD1,CPE,TSHR,KLHL29,GLDC,MEIS2,EML6,DCDC1,SMAD9,DCC,ALDH1L2,CAP2,KLHL4,SLC25A28,PRKAR2B,ABCC2,TNS1,ZDHHC14,CA13,GPC6,GNAI1,AHRR,SH3RF1,ATP7B,CCBE1,RASGRF2,MAP9,ARHGAP28,SEMA3C,INPP5F,ZBTB20,CAB39L,NRP1,DNHD1,TMEFF2,SPOCK3,EFNB2,CARS,LRFN5,SCN5A,LATS2,MRC2,CELSR1,EHHADH,PTPRD,TBC1D1,GABRB2,ITGA6,OPHN1,SLC25A27,MRPL22,TJP1,SLC1A3,WDFY4,GPSM2,APBA1,TNFRSF19,DYNC1I1,MCOLN2,BNIP1,FRY,KIAA1257,KIAA1671,APLF,FAM189A1,PRKG1,SRGAP1,GRIP1,TOX,CADPS2,ALPK1,SAMD13,FIGN,NCAM1,FAM155A,PRR16,FMNL2,IGSF3,SLC37A1,KCNQ3,TBC1D8B,SPATA6,RAPGEF4,DCHS1,FHL2,RYR2,AIG1,ST6GALNAC3,PEX5L,SHISA2,CCDC85A,SNAP25,TAF4B,PLCB1,MBNL2,MMP15,CACHD1,RIMKLB,SH3GL2,ADAMTS3,PELI2,CECR2,C1orf21,LRRIQ3,EMILIN2,DYNC2LI1,CLMN,SLFN5,CDH2,AMPD1,EPHA3,DNM3,ZNF516,TCTN2,RASAL2,ST14,FAM131C,ZNF311,PLXNA2,BEGAIN,RGS20,PKP2,CHUK,SPATS2L,COLEC10,COL14A1,TIAM2,EPB41L3,ZNF827,ZNF438,KMO,POU5F1B,COL25A1,CNKSR3,ALDH1L1,NBEA,ATP6AP1L,KIAA1549,GATM,KCNB2,C3orf67,GAB2,MYLK3,RNF145,KCNH5,SHANK2,ADCY1,PREX1,NLGN4X,SATB2,PRKCQ,TTC28,DSP,ASPH,FGFR1,MAGI3,HTR7,ARHGAP21,IKZF3,IQCH,KLHL31,CTTNBP2,NR3C2,COBL,MID1,STON2,PURG,HACE1,ANO10,MYO1D,WDR17,ROBO2,BACE1,EPS8,UBAC2,NKAIN2,PSD3,CREB5,TPD52L1,COL27A1,RGS17,GPR155,SGK3,RALGAPA2,SLC6A15,MYO6,TBC1D9,C15orf41,SMPDL3A,MED12L,B4GALT6,PARP9,TMC7,VAV3,SYNPO2,ARAP2,LCA5,CLYBL,MCF2L2,RAPGEF2,RASA3,ATP11A,CTTNBP2NL,GUCY1A2,SNTB1,SKAP1,PLOD2,TERT,PLXDC2,OSBPL5,SLCO5A1,SVIL,NEK11,MYOM2,DOCK6,BTRC,TLL2,NUDT17,PHACTR3,UGT8,SYT12,PTPN21,FHDC1,LILRB1,ANKRD18A,ITPR2,FAM13A,IKZF2,DNER,KREMEN1,SLCO3A1,HMCN1,FSTL5,PLS3,ANKRD42,RTN1,PPM1E,FKBP9,KCNN2,AKAP7,SLC10A7,ANKFN1,ITGB3,MPPED2,COL19A1,POF1B,LIN7A,JAKMIP2,KIAA1614,MYRIP,IL1RAP,NEB,SLIT2,RAPGEF5,PGBD5,LAMP3,GPM6A,ABCC4,SPOCD1,ANK2,GDPD1,CR2,ROR1,COTL1,SGK2,SESN1,CRYBG3,SERGEF,TMEM132B,TCF7L1,KCNMB4,KLF12,ITGBL1,NCAM2,FAM114A2,CCDC146,DLX2,MAGI2,MLLT3,FRMD5,HS6ST3,CHMP4C,FN1,UBASH3B,STXBP6,ELOVL7,RIMKLA,CYP4V2,GALNT13,CHSY1,FAM81A,MLC1,SPINK5,SATB1,DOK5,FHOD3,GALNT1,ZBTB38,CA2,IGF1R,ABCA5,FRAS1,RPS11,SAMD11,FAM107B,LIMCH1,FBXL2,BARX1,CAND2,CKAP4,SNX7,NOS3,ZNF629,CHSY3,GPR176,UNC5C,PODXL2,TMTC4,EDEM3,WDR25,OBSCN,PDE8A,SDK1,LHPP,KHDRBS2,HERPUD1,NEGR1,GRIK4,KIAA0355,FAT1,CSF1,RAI14,TMEM117,PTPRN2,SEMA3A,XKR4,MME,SFN,CREB3L2,DMXL2,EML5,DOCK1,PLEKHA5,HECW2,COL18A1,RHPN2,COBLL1,DOCK2,CYP26A1,TBC1D19,COL22A1,PDZD8,TACC2,KAZN,ZDHHC6,ZNF521,MAP7,MYH15,FHIT,MET,FAM78B,FER,UROS,PTPN6,THSD4,TES,C3orf52,FGF12,ACO1,CHRNA6,VIM,TTLL7,DOCK5,TPK1,BCL11A,ZNF569,ARMC4,NRG3,PTPRJ,LMLN,BACH2,PTK7,RBPMS2,MAOA,HGF,RNF130,SUSD4,LIFR,CTNND2,PSPH,TENM1,TNIK,LPAR2,BMPR2,ARHGEF11,GRB14,ARL15,MCTP2,NSUN6,CLSTN2,GABRG2,SELL,HBE1,SEL1L3,BMP6,PPP2R3A,SLC35F1,CHN2,MAP1A,RASD2,KCNMB3,TSC22D1,KIAA0319,PRICKLE2,KLF9,IQGAP3,RRAS2,TNFRSF11A,DLGAP1,MICAL2,RAB3B,LRRIQ1,CRIM1,ESRRG,OGDHL,GRID1,FERMT2,ARHGAP32,PALLD,ZFPM2,NAALADL2,MAP1B,RERE,MKX,CTIF,EBF1,ADAMTS17,DPY19L2,DDAH1,ICA1,DOCK7,EDA,FBN1,MPP7,L3MBTL4,NACC2,THSD7B,ZNF808,DLG2,KIF21A,TBC1D4,IL9R,KIF1B,MMP16,NPHP1,CACNA2D1 |
| 1.642e-27 | -61.67 | angiosarcoma | COSMIC cancer mutations | angiosarcoma | 2247 | 372 | 17385 | 1698 |
ARHGAP26,FAM171B,GXYLT2,LGR4,SIDT1,AASS,CNTNAP3,RECK,ATP8A1,DNAJC3,PPFIBP2,ENAH,CADM2,CA8,DACH2,EYA4,SLC9A7,HECTD2,SKI,PCDH7,DNAH6,SLC16A2,PPFIA2,FAAH2,ATRNL1,PPP2R2B,VWA5A,TSHR,GLDC,MEIS2,ERGIC1,EML6,DCDC1,DCC,TGFA,CAP2,LRMP,ABCC2,TNS1,GPC6,AHRR,WIPF3,ATP7B,SEMA3C,INPP5F,DSEL,CAB39L,TANC2,DNHD1,FAM124A,TBC1D1,OPHN1,SLC36A4,SLC1A3,WDFY4,APBA1,DYNC1I1,TTC30B,MECOM,RALGPS2,FRY,BACE2,FAM189A1,VWDE,PRKG1,SRGAP1,GRIP1,CPXM2,TOX,CADPS2,ST8SIA1,JAM2,STXBP1,FMNL2,RIMS2,EPB41L5,KCNQ3,SLC36A1,STAT4,RAPGEF4,RYR2,TTC30A,CCDC85A,PLCB1,SPATA7,BEX4,TMCO3,PLEKHH2,SH3GL2,PMEPA1,DYNC2LI1,CDH17,CDH2,PLA2G4A,EPHA3,TBKBP1,ZNF516,TCTN2,ELOVL4,RASAL2,FAM131C,GALNT6,MSR1,PLXNA2,PKP2,GRK6,COL14A1,ZNF827,SPEG,KMO,CNKSR3,SHF,NBEA,FAM133A,RTKN2,FAM155B,DNAH5,KCNB2,C3orf67,NECAB1,KCNH5,ADCY1,SATB2,TTC28,ASPH,TBC1D16,TRIQK,ATP10D,FGFR1,HTR7,ZNF704,PLEKHG1,ALG11,HPGD,HS3ST3B1,LRRC27,NR3C2,COBL,MID1,DENND5B,ANO10,MYO1D,CCDC148,FARP1,WDR17,ROBO2,EDA2R,GLIPR1L1,EPS8,UBAC2,NKAIN2,PSD3,CREB5,TPD52L1,GHR,TBC1D9,PFKFB4,VAV3,ARHGEF28,SYNPO2,CLYBL,CACNA1E,MCF2L2,PTPN13,ZDHHC15,ATP11A,UCHL3,GUCY1A2,SNTB1,SKAP1,GPR137C,ZIC1,HEG1,GALNT3,PCDHB7,TERT,PLXDC2,GNAO1,SLCO5A1,NEK11,GRIN2D,MYOM2,BTRC,PHC1,PHACTR3,CACNG3,KIF5A,ITPR2,FAM13A,NUP62CL,NOVA1,DNER,CACNB4,KREMEN1,HMCN1,FSTL5,RTN1,PPM1E,SIPA1L2,ANKFN1,SLC10A7,MPPED2,COL19A1,POF1B,LIN7A,TRPC1,JAKMIP2,SLC2A12,PCOLCE2,MYRIP,FANK1,SLIT2,GPM6A,MARK1,SKAP2,ANK2,CAPN5,CR2,PLEKHA1,TCERG1L,SERGEF,EML1,TMEM132B,KCNMB4,HPSE,ITGBL1,NCAM2,MAP2,GNB4,FAM114A2,CCDC146,PPARGC1A,TNFSF4,APBA2,MAGI2,TC2N,MLLT3,FRMD5,HS6ST3,UST,BCL11B,MOCOS,STXBP5L,ZCCHC24,UBASH3B,SETBP1,GALNT13,DOK5,PGAP1,FHOD3,KIAA1958,PRTFDC1,SLC30A4,IGF1R,FRAS1,FAM107B,LRP6,LIMCH1,SLCO4C1,CHSY3,GPR176,UNC5C,PCDH10,MGAT4B,SDK1,KHDRBS2,TEX9,NEGR1,TBC1D2,GRIK4,TMEM154,FAT1,TMEM117,PTPRN2,PLD1,OSBPL6,XKR4,MME,CREB3L2,DMXL2,EML5,CFH,DOCK1,PLEKHA5,XYLT1,RHPN2,RADIL,DOCK2,PCLO,SCIN,TBC1D19,KAZN,MYO3B,ZNF521,MAP7,MYH15,FHIT,MDH1B,MET,INTU,FER,PTPRU,SLC39A8,THSD4,TES,FGF12,FBXO36,DOCK5,FRK,TPK1,SMAD3,ARMC4,RANBP2,NRG3,PTPRJ,ITGA2,HGF,CYP2U1,PSPH,CTNND2,MAST1,COL9A3,BMPR2,GRB14,ARHGEF11,CMTM8,MCTP2,LRP4,TNFSF13B,CLSTN2,RASD1,PRDM8,NOTUM,ARHGAP44,PPP2R3A,MCU,SLC35F1,MAP1A,DSG2,TSC22D1,KIAA0319,AFAP1L2,SH3PXD2B,IQGAP3,KIAA1211,DLGAP1,CRIM1,GRID1,FERMT2,PALLD,FNDC3A,GALNT14,NAALADL2,MAP1B,RERE,EBF1,ADAMTS17,ICA1,DOCK7,L3MBTL4,FBN1,FMO4,THSD7B,UACA,ZNF474,SLC22A15,KIF21A,TBC1D4,MMP16,MAP3K20,CACNA2D1,SLC16A10 |
| 1.642e-27 | -61.67 | soft_tissue-blood_vessel-angiosarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-angiosarcoma | 2247 | 372 | 17385 | 1698 |
ARHGAP26,FAM171B,GXYLT2,LGR4,SIDT1,AASS,CNTNAP3,RECK,ATP8A1,DNAJC3,PPFIBP2,ENAH,CADM2,CA8,DACH2,EYA4,SLC9A7,HECTD2,SKI,PCDH7,DNAH6,SLC16A2,PPFIA2,FAAH2,ATRNL1,PPP2R2B,VWA5A,TSHR,GLDC,MEIS2,ERGIC1,EML6,DCDC1,DCC,TGFA,CAP2,LRMP,ABCC2,TNS1,GPC6,AHRR,WIPF3,ATP7B,SEMA3C,INPP5F,DSEL,CAB39L,TANC2,DNHD1,FAM124A,TBC1D1,OPHN1,SLC36A4,SLC1A3,WDFY4,APBA1,DYNC1I1,TTC30B,MECOM,RALGPS2,FRY,BACE2,FAM189A1,VWDE,PRKG1,SRGAP1,GRIP1,CPXM2,TOX,CADPS2,ST8SIA1,JAM2,STXBP1,FMNL2,RIMS2,EPB41L5,KCNQ3,SLC36A1,STAT4,RAPGEF4,RYR2,TTC30A,CCDC85A,PLCB1,SPATA7,BEX4,TMCO3,PLEKHH2,SH3GL2,PMEPA1,DYNC2LI1,CDH17,CDH2,PLA2G4A,EPHA3,TBKBP1,ZNF516,TCTN2,ELOVL4,RASAL2,FAM131C,GALNT6,MSR1,PLXNA2,PKP2,GRK6,COL14A1,ZNF827,SPEG,KMO,CNKSR3,SHF,NBEA,FAM133A,RTKN2,FAM155B,DNAH5,KCNB2,C3orf67,NECAB1,KCNH5,ADCY1,SATB2,TTC28,ASPH,TBC1D16,TRIQK,ATP10D,FGFR1,HTR7,ZNF704,PLEKHG1,ALG11,HPGD,HS3ST3B1,LRRC27,NR3C2,COBL,MID1,DENND5B,ANO10,MYO1D,CCDC148,FARP1,WDR17,ROBO2,EDA2R,GLIPR1L1,EPS8,UBAC2,NKAIN2,PSD3,CREB5,TPD52L1,GHR,TBC1D9,PFKFB4,VAV3,ARHGEF28,SYNPO2,CLYBL,CACNA1E,MCF2L2,PTPN13,ZDHHC15,ATP11A,UCHL3,GUCY1A2,SNTB1,SKAP1,GPR137C,ZIC1,HEG1,GALNT3,PCDHB7,TERT,PLXDC2,GNAO1,SLCO5A1,NEK11,GRIN2D,MYOM2,BTRC,PHC1,PHACTR3,CACNG3,KIF5A,ITPR2,FAM13A,NUP62CL,NOVA1,DNER,CACNB4,KREMEN1,HMCN1,FSTL5,RTN1,PPM1E,SIPA1L2,ANKFN1,SLC10A7,MPPED2,COL19A1,POF1B,LIN7A,TRPC1,JAKMIP2,SLC2A12,PCOLCE2,MYRIP,FANK1,SLIT2,GPM6A,MARK1,SKAP2,ANK2,CAPN5,CR2,PLEKHA1,TCERG1L,SERGEF,EML1,TMEM132B,KCNMB4,HPSE,ITGBL1,NCAM2,MAP2,GNB4,FAM114A2,CCDC146,PPARGC1A,TNFSF4,APBA2,MAGI2,TC2N,MLLT3,FRMD5,HS6ST3,UST,BCL11B,MOCOS,STXBP5L,ZCCHC24,UBASH3B,SETBP1,GALNT13,DOK5,PGAP1,FHOD3,KIAA1958,PRTFDC1,SLC30A4,IGF1R,FRAS1,FAM107B,LRP6,LIMCH1,SLCO4C1,CHSY3,GPR176,UNC5C,PCDH10,MGAT4B,SDK1,KHDRBS2,TEX9,NEGR1,TBC1D2,GRIK4,TMEM154,FAT1,TMEM117,PTPRN2,PLD1,OSBPL6,XKR4,MME,CREB3L2,DMXL2,EML5,CFH,DOCK1,PLEKHA5,XYLT1,RHPN2,RADIL,DOCK2,PCLO,SCIN,TBC1D19,KAZN,MYO3B,ZNF521,MAP7,MYH15,FHIT,MDH1B,MET,INTU,FER,PTPRU,SLC39A8,THSD4,TES,FGF12,FBXO36,DOCK5,FRK,TPK1,SMAD3,ARMC4,RANBP2,NRG3,PTPRJ,ITGA2,HGF,CYP2U1,PSPH,CTNND2,MAST1,COL9A3,BMPR2,GRB14,ARHGEF11,CMTM8,MCTP2,LRP4,TNFSF13B,CLSTN2,RASD1,PRDM8,NOTUM,ARHGAP44,PPP2R3A,MCU,SLC35F1,MAP1A,DSG2,TSC22D1,KIAA0319,AFAP1L2,SH3PXD2B,IQGAP3,KIAA1211,DLGAP1,CRIM1,GRID1,FERMT2,PALLD,FNDC3A,GALNT14,NAALADL2,MAP1B,RERE,EBF1,ADAMTS17,ICA1,DOCK7,L3MBTL4,FBN1,FMO4,THSD7B,UACA,ZNF474,SLC22A15,KIF21A,TBC1D4,MMP16,MAP3K20,CACNA2D1,SLC16A10 |
| 6.382e-27 | -60.32 | acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | acute_myeloid_leukaemia_therapy_related | 1558 | 283 | 17385 | 1698 |
ARHGAP26,MYCBP2,GXYLT2,ATP8A1,NPM1,ENAH,CEBPA,CADM2,KIAA1217,DACH2,PCDH7,PPFIA2,SERINC2,CHRDL1,ATRNL1,PPP2R2B,COG3,KLHL29,TSHR,MEIS2,EML6,DCC,NR6A1,CAP2,GPC6,ENPP1,CCBE1,RASGRF2,TANC2,UNC5B,TMEM63C,CELSR1,EHHADH,CYP2J2,OPHN1,TJP1,SLC1A3,WDFY4,APBA1,DYNC1I1,CHN1,NAV1,SLC7A11,FRY,FAM189A1,PRKG1,CADPS2,ST8SIA1,FIGN,NCAM1,FAM155A,JAM2,PRR16,FMNL2,COL9A2,EPB41L5,BDNF,QSOX1,KCNQ3,TBC1D8B,COL4A4,RAPGEF4,RYR2,ST6GALNAC3,PEX5L,CCDC85A,TAF4B,PLCB1,CACHD1,SH3GL2,ADAMTS3,CECR2,LRRIQ3,CLMN,LAPTM4B,PLA2G4A,DNM3,PLXNA2,RGS20,SPATS2L,ZNF827,ASNS,CNKSR3,COL25A1,RTKN2,DNAH5,KCNB2,SCN3A,KCNH5,PANK1,TRAM1L1,ADCY1,PREX1,NLGN4X,SATB2,TTC28,ASPH,HTR7,IQCH,PRKCB,WFS1,INPP4B,GRB10,NR3C2,DENND5B,ANO10,WASF3,MYO1D,FARP1,MXI1,WDR17,ROBO2,NKAIN2,EPHB1,AFF2,C15orf41,B4GALT6,TRPM4,VAV3,SYNPO2,CLYBL,CACNA1E,PTPN13,ATP11A,CTTNBP2NL,GUCY1A2,SKAP1,GALNT3,PLXDC2,GNAO1,SVIL,HK1,CMPK2,SHOX2,DOCK6,CRISPLD1,BTRC,LARP1,PHACTR3,UGT8,FHDC1,LMCD1,C20orf194,ITPR2,FAM13A,NOVA1,DNER,HMCN1,CHST10,CEP85L,FSTL5,LGI2,RTN1,PPM1E,SIPA1L2,TM9SF2,KCNN2,ITGB3,ANKFN1,SLC10A7,TRPC1,COL19A1,KIAA1614,MYRIP,SLIT2,MARK1,ANK2,ROR1,TCERG1L,SESN1,EML1,TMEM132B,NCAM2,MAP2,ITGBL1,CCDC146,NCOA7,MAGI2,MLLT3,FRMD5,RRAGD,HS6ST3,UST,BCL11B,LONRF1,STXBP5L,ZCCHC24,SETBP1,GALNT13,SATB1,DOK5,FHOD3,CA2,FRAS1,FAM107B,LIMCH1,SLCO4C1,NIPAL2,UNC5C,PCDH10,IL17RD,GPR176,SLC27A2,TMTC4,SDK1,PRDM1,KHDRBS2,NEGR1,GRIK4,FCHO2,FAT1,HK2,PTPRN2,TMEM117,SEMA3A,PANK3,XKR4,CFH,DOCK1,XYLT1,COL18A1,DOCK2,PPP1R9A,TBC1D19,COL22A1,UNC13B,TACC2,ZNF521,ACVR2A,MYH15,FHIT,MDH1B,CLVS2,TMEM56,FER,THSD4,FGF12,DOCK5,FRK,JAM3,WARS,TPK1,SMAD3,NRG3,RNF130,TTC39A,CTNND2,TSPAN15,ARHGEF11,LRP4,CLSTN2,BMP6,PPP2R3A,ARHGAP44,FSD1,SLC35F1,CHN2,STC2,IPCEF1,FKBP14,TNFRSF11A,DLGAP1,MICAL2,CRIM1,ESRRG,SYBU,GRID1,PHACTR2,ZFPM2,PALLD,GALNT14,NAALADL2,MAP1B,EBF1,ADAMTS17,DDAH1,L3MBTL4,MAP2K6,THSD7B,MAP3K20,PTGES,CACNA2D1,ABCG1 |
| 6.382e-27 | -60.32 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | 1558 | 283 | 17385 | 1698 |
ARHGAP26,MYCBP2,GXYLT2,ATP8A1,NPM1,ENAH,CEBPA,CADM2,KIAA1217,DACH2,PCDH7,PPFIA2,SERINC2,CHRDL1,ATRNL1,PPP2R2B,COG3,KLHL29,TSHR,MEIS2,EML6,DCC,NR6A1,CAP2,GPC6,ENPP1,CCBE1,RASGRF2,TANC2,UNC5B,TMEM63C,CELSR1,EHHADH,CYP2J2,OPHN1,TJP1,SLC1A3,WDFY4,APBA1,DYNC1I1,CHN1,NAV1,SLC7A11,FRY,FAM189A1,PRKG1,CADPS2,ST8SIA1,FIGN,NCAM1,FAM155A,JAM2,PRR16,FMNL2,COL9A2,EPB41L5,BDNF,QSOX1,KCNQ3,TBC1D8B,COL4A4,RAPGEF4,RYR2,ST6GALNAC3,PEX5L,CCDC85A,TAF4B,PLCB1,CACHD1,SH3GL2,ADAMTS3,CECR2,LRRIQ3,CLMN,LAPTM4B,PLA2G4A,DNM3,PLXNA2,RGS20,SPATS2L,ZNF827,ASNS,CNKSR3,COL25A1,RTKN2,DNAH5,KCNB2,SCN3A,KCNH5,PANK1,TRAM1L1,ADCY1,PREX1,NLGN4X,SATB2,TTC28,ASPH,HTR7,IQCH,PRKCB,WFS1,INPP4B,GRB10,NR3C2,DENND5B,ANO10,WASF3,MYO1D,FARP1,MXI1,WDR17,ROBO2,NKAIN2,EPHB1,AFF2,C15orf41,B4GALT6,TRPM4,VAV3,SYNPO2,CLYBL,CACNA1E,PTPN13,ATP11A,CTTNBP2NL,GUCY1A2,SKAP1,GALNT3,PLXDC2,GNAO1,SVIL,HK1,CMPK2,SHOX2,DOCK6,CRISPLD1,BTRC,LARP1,PHACTR3,UGT8,FHDC1,LMCD1,C20orf194,ITPR2,FAM13A,NOVA1,DNER,HMCN1,CHST10,CEP85L,FSTL5,LGI2,RTN1,PPM1E,SIPA1L2,TM9SF2,KCNN2,ITGB3,ANKFN1,SLC10A7,TRPC1,COL19A1,KIAA1614,MYRIP,SLIT2,MARK1,ANK2,ROR1,TCERG1L,SESN1,EML1,TMEM132B,NCAM2,MAP2,ITGBL1,CCDC146,NCOA7,MAGI2,MLLT3,FRMD5,RRAGD,HS6ST3,UST,BCL11B,LONRF1,STXBP5L,ZCCHC24,SETBP1,GALNT13,SATB1,DOK5,FHOD3,CA2,FRAS1,FAM107B,LIMCH1,SLCO4C1,NIPAL2,UNC5C,PCDH10,IL17RD,GPR176,SLC27A2,TMTC4,SDK1,PRDM1,KHDRBS2,NEGR1,GRIK4,FCHO2,FAT1,HK2,PTPRN2,TMEM117,SEMA3A,PANK3,XKR4,CFH,DOCK1,XYLT1,COL18A1,DOCK2,PPP1R9A,TBC1D19,COL22A1,UNC13B,TACC2,ZNF521,ACVR2A,MYH15,FHIT,MDH1B,CLVS2,TMEM56,FER,THSD4,FGF12,DOCK5,FRK,JAM3,WARS,TPK1,SMAD3,NRG3,RNF130,TTC39A,CTNND2,TSPAN15,ARHGEF11,LRP4,CLSTN2,BMP6,PPP2R3A,ARHGAP44,FSD1,SLC35F1,CHN2,STC2,IPCEF1,FKBP14,TNFRSF11A,DLGAP1,MICAL2,CRIM1,ESRRG,SYBU,GRID1,PHACTR2,ZFPM2,PALLD,GALNT14,NAALADL2,MAP1B,EBF1,ADAMTS17,DDAH1,L3MBTL4,MAP2K6,THSD7B,MAP3K20,PTGES,CACNA2D1,ABCG1 |
| 8.901e-27 | -59.98 | blood_vessel | COSMIC cancer mutations | blood_vessel | 2266 | 372 | 17385 | 1698 |
ARHGAP26,FAM171B,GXYLT2,LGR4,SIDT1,AASS,CNTNAP3,RECK,ATP8A1,DNAJC3,PPFIBP2,ENAH,CADM2,CA8,DACH2,EYA4,SLC9A7,HECTD2,SKI,PCDH7,DNAH6,SLC16A2,PPFIA2,FAAH2,ATRNL1,PPP2R2B,VWA5A,TSHR,GLDC,MEIS2,ERGIC1,EML6,DCDC1,DCC,TGFA,CAP2,LRMP,ABCC2,TNS1,GPC6,AHRR,WIPF3,ATP7B,SEMA3C,INPP5F,DSEL,CAB39L,TANC2,DNHD1,FAM124A,TBC1D1,OPHN1,SLC36A4,SLC1A3,WDFY4,APBA1,DYNC1I1,TTC30B,MECOM,RALGPS2,FRY,BACE2,FAM189A1,VWDE,PRKG1,SRGAP1,GRIP1,CPXM2,TOX,CADPS2,ST8SIA1,JAM2,STXBP1,FMNL2,RIMS2,EPB41L5,KCNQ3,SLC36A1,STAT4,RAPGEF4,RYR2,TTC30A,CCDC85A,PLCB1,SPATA7,BEX4,TMCO3,PLEKHH2,SH3GL2,PMEPA1,DYNC2LI1,CDH17,CDH2,PLA2G4A,EPHA3,TBKBP1,ZNF516,TCTN2,ELOVL4,RASAL2,FAM131C,GALNT6,MSR1,PLXNA2,PKP2,GRK6,COL14A1,ZNF827,SPEG,KMO,CNKSR3,SHF,NBEA,FAM133A,RTKN2,FAM155B,DNAH5,KCNB2,C3orf67,NECAB1,KCNH5,ADCY1,SATB2,TTC28,ASPH,TBC1D16,TRIQK,ATP10D,FGFR1,HTR7,ZNF704,PLEKHG1,ALG11,HPGD,HS3ST3B1,LRRC27,NR3C2,COBL,MID1,DENND5B,ANO10,MYO1D,CCDC148,FARP1,WDR17,ROBO2,EDA2R,GLIPR1L1,EPS8,UBAC2,NKAIN2,PSD3,CREB5,TPD52L1,GHR,TBC1D9,PFKFB4,VAV3,ARHGEF28,SYNPO2,CLYBL,CACNA1E,MCF2L2,PTPN13,ZDHHC15,ATP11A,UCHL3,GUCY1A2,SNTB1,SKAP1,GPR137C,ZIC1,HEG1,GALNT3,PCDHB7,TERT,PLXDC2,GNAO1,SLCO5A1,NEK11,GRIN2D,MYOM2,BTRC,PHC1,PHACTR3,CACNG3,KIF5A,ITPR2,FAM13A,NUP62CL,NOVA1,DNER,CACNB4,KREMEN1,HMCN1,FSTL5,RTN1,PPM1E,SIPA1L2,ANKFN1,SLC10A7,MPPED2,COL19A1,POF1B,LIN7A,TRPC1,JAKMIP2,SLC2A12,PCOLCE2,MYRIP,FANK1,SLIT2,GPM6A,MARK1,SKAP2,ANK2,CAPN5,CR2,PLEKHA1,TCERG1L,SERGEF,EML1,TMEM132B,KCNMB4,HPSE,ITGBL1,NCAM2,MAP2,GNB4,FAM114A2,CCDC146,PPARGC1A,TNFSF4,APBA2,MAGI2,TC2N,MLLT3,FRMD5,HS6ST3,UST,BCL11B,MOCOS,STXBP5L,ZCCHC24,UBASH3B,SETBP1,GALNT13,DOK5,PGAP1,FHOD3,KIAA1958,PRTFDC1,SLC30A4,IGF1R,FRAS1,FAM107B,LRP6,LIMCH1,SLCO4C1,CHSY3,GPR176,UNC5C,PCDH10,MGAT4B,SDK1,KHDRBS2,TEX9,NEGR1,TBC1D2,GRIK4,TMEM154,FAT1,TMEM117,PTPRN2,PLD1,OSBPL6,XKR4,MME,CREB3L2,DMXL2,EML5,CFH,DOCK1,PLEKHA5,XYLT1,RHPN2,RADIL,DOCK2,PCLO,SCIN,TBC1D19,KAZN,MYO3B,ZNF521,MAP7,MYH15,FHIT,MDH1B,MET,INTU,FER,PTPRU,SLC39A8,THSD4,TES,FGF12,FBXO36,DOCK5,FRK,TPK1,SMAD3,ARMC4,RANBP2,NRG3,PTPRJ,ITGA2,HGF,CYP2U1,PSPH,CTNND2,MAST1,COL9A3,BMPR2,GRB14,ARHGEF11,CMTM8,MCTP2,LRP4,TNFSF13B,CLSTN2,RASD1,PRDM8,NOTUM,ARHGAP44,PPP2R3A,MCU,SLC35F1,MAP1A,DSG2,TSC22D1,KIAA0319,AFAP1L2,SH3PXD2B,IQGAP3,KIAA1211,DLGAP1,CRIM1,GRID1,FERMT2,PALLD,FNDC3A,GALNT14,NAALADL2,MAP1B,RERE,EBF1,ADAMTS17,ICA1,DOCK7,L3MBTL4,FBN1,FMO4,THSD7B,UACA,ZNF474,SLC22A15,KIF21A,TBC1D4,MMP16,MAP3K20,CACNA2D1,SLC16A10 |
| 1.139e-26 | -59.74 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | 7398 | 930 | 17385 | 1698 |
ARHGAP26,DOC2A,GXYLT2,FLVCR2,AASS,RECK,DNAJC3,NPM1,STAT5B,CTBP2,CADM2,BCAN,KIAA1217,SNX9,CA8,ABHD6,EYA4,NOS1AP,SKI,PCDH7,EPDR1,TXNDC5,TGFBR3,DNAH6,PPFIA2,FAAH2,RAP2A,PPP2R2B,COG3,CPE,TSHR,MEIS2,DCC,WLS,TGFA,CAP2,GJB2,LRRK2,NFIA,ELMOD1,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,F12,MFSD6,INTS6,CA13,SLC7A1,ENPP1,MAP9,ARHGAP28,ERCC5,INPP5F,ZBTB20,CAB39L,TMOD2,DNHD1,TMEFF2,VASH2,CRYL1,CARS,SCN5A,LATS2,TMEM63C,TJP1,SLC36A4,FOXG1,BBS9,CHN1,SYCP2,RSL24D1,FRY,KIAA1671,PAIP2B,BACE2,APLF,FAM189A1,CACNB2,PRELID2,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,ST8SIA1,FIGN,NCAM1,MOXD1,JAM2,GLIS1,STXBP1,TSPAN9,GFRA1,FMNL2,LRP12,BDNF,SLC37A1,PNP,KCNQ3,MYO10,STAT4,SPATA6,ARID5B,FASN,FHL2,RYR2,HIP1,CALCRL,SMARCD3,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,TAF4B,MBNL2,SPATA7,DHX32,BEX4,CACHD1,TEX15,TMCO3,RIMKLB,SH3GL2,ADAMTS3,EMILIN2,CDH17,CLMN,LAPTM4B,CDH2,TRPC3,DOCK9,TFCP2L1,DNM3,ZNF516,GALNT6,MYO1B,LRRCC1,RGS20,PKP2,ADD2,IL13RA1,COLEC10,LCP2,NRXN1,TXNRD3,CDS1,EPB41L3,RNF150,CNKSR3,COL25A1,ALDH1L1,RTKN2,RAB27B,JAKMIP3,DNAH5,KCNB2,PERP,DOCK8,SCN3A,C3orf67,SSH3,MYLK3,GARS,GAPDH,RNF145,NECAB1,EBPL,PFKFB2,FZD4,NKX3-2,KCNH5,ADCY1,RAB38,TTC28,DSP,ASPH,ZNF618,FGFR1,ENTPD1,IQCK,ARHGAP21,IQCH,GYPC,PDLIM3,WFS1,PEMT,WWTR1,LAMB1,INPP4B,PLEKHG1,ALG11,FAM149A,PLD5,CCDC148,FARP1,TMEM132C,WDR17,C1QTNF3,ROBO2,EDA2R,FZD8,UBAC2,NKAIN2,PSD3,CREB5,EPHB1,KCNC4,COL27A1,NEO1,GHR,MYO6,ZFP36L2,C15orf41,MED12L,TRPM4,PDLIM7,MN1,RAB6B,CLYBL,MCF2L2,RAPGEF2,AK4,RASA3,ATP11A,SNTB1,HEG1,GALNT3,PTPRC,NSD1,GNAO1,OSBPL5,SLCO5A1,NEK11,HK1,DOCK6,ATP2B4,DCBLD1,BTRC,TLL2,CCDC126,PHACTR3,CACNG3,SYT12,FHDC1,LMCD1,ASS1,LILRB1,ITPR2,SYT14,FAM13A,NOVA1,FSTL5,PLS3,ANKRD42,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,KCNAB1,SEC16B,KCNN2,MARVELD2,ITGB3,TMEM143,MPPED2,COL19A1,LIN7A,JAKMIP2,TLN2,TMEM132E,TLR4,RAPGEF5,NEB,PGBD5,SLC3A2,GCNT2,MARK1,CD55,KCNIP3,ABCC4,COL4A3,SPOCD1,ANK2,GDPD1,CR2,TCERG1L,SESN1,CRYBG3,DYRK1B,TCF7L1,KLF12,MAP2,P4HA2,TECPR2,CCDC146,PIK3C2B,MLLT3,TC2N,HS6ST3,RRAGD,CHMP4C,LONRF1,STXBP5L,LGALS3,UBASH3B,SETBP1,SORBS3,ZNF215,MLC1,PGAP1,DOK5,FHOD3,GALNT1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,ZNF440,FRAS1,PDE10A,GAN,LRP6,BNIP3,SLCO4C1,FAR2,FBXL2,VGLL4,CHSY3,UNC5C,SLC27A2,MGAT4B,EFNA3,TMTC4,TCEA3,SPATA13,WDR25,OBSCN,PDE8A,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,MAPKAPK2,GRIK4,PLD1,SEMA3A,RNF122,TESC,MME,SIX2,CFH,DOCK1,LPCAT2,XYLT1,RHPN2,NTRK3,OR51B4,SLC7A2,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,TBC1D19,TACC2,MYO3B,EEPD1,MYH15,CLVS2,SCN2A,FAM78B,TMEM56,INTU,LRRC8B,THSD4,ACO1,FGF12,RNF125,GSTO1,FBXO36,FRK,JAM3,SMAD3,NRG3,PTPRJ,RNF217,PTK7,ITGA2,ABI3,KCNG1,PTPRS,MAOA,HGF,MBOAT2,CTNND2,CNTN1,MAN2B2,TENM1,COL9A3,DYRK3,BMPR2,KLHL13,GRB14,MCTP2,BLVRB,GABRG2,PRDM8,ARHGAP44,SLC35F1,TECPR1,MAP1A,KCNMB3,GTF2F2,TSC22D1,SGK1,PRICKLE2,TSPAN13,SH3PXD2B,KLF9,ESD,KIAA1211,ATP2B1,DLGAP1,MICAL2,FOXN3,FERMT2,FNDC3A,PALLD,EXOG,ILDR2,MGMT,MKX,EBF1,DDAH1,DOCK7,TMEM237,FAT4,FBN1,L3MBTL4,FMO4,DLG2,PAX9,SLC1A5,TBC1D4,KIF1B,FILIP1,CACNA2D1,C2orf27A,ZNF235,FAM171B,CGN,PPP4R4,PAGE1,DUSP8,LGR4,SIDT1,TCP11L2,ATP8A1,LDLR,PPFIBP2,ENAH,PRKCA,AARS,DACH2,SLC9A7,TRPS1,ZFYVE28,FAM168A,CFHR1,SLC16A2,CHRDL1,ATRNL1,BEND4,VWA5A,PLTP,GLDC,GDAP1,ERGIC1,EML6,DCDC1,ACVR1C,NR6A1,WISP3,KLHL3,KLHL4,ALDH1L2,DNAJC6,LRMP,DEPTOR,TNS1,EFHC1,SAV1,ZDHHC14,GPC6,AHRR,SH3RF1,ENPP6,NCKAP1L,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,MAPK13,SERPINI1,NRP1,TANC2,UNC5B,SPOCK3,EFNB2,SEMA6B,KLF8,MRC2,FAM124A,CELSR1,EHHADH,PTPRD,TBC1D1,GABRB2,DHCR24,OLAH,SLC25A27,OPHN1,GTF2IRD1,LRRC49,SLC1A3,TNFRSF10C,WDFY4,APBA1,TNFRSF19,ADSSL1,DYNC1I1,MTUS1,MCOLN2,ABLIM1,NAV1,RALGPS2,SLC7A11,CNTN4,PIK3AP1,RUNDC3B,PRKG1,CPXM2,GRIP1,SAMD13,PRR16,FAM155A,RIMS2,RNF152,PTCH2,TBC1D8B,SLC36A1,COL4A4,VLDLR,RAPGEF4,PACSIN3,KIAA1324L,TTYH2,PEX5L,CCDC85A,RABAC1,CDC42BPA,PLCB1,PLEKHH2,PMEPA1,PELI2,CECR2,THBS4,C1orf21,LRRIQ3,MPP2,DYNC2LI1,IQSEC2,ANKRD20A5P,FRMPD3,EPHA3,PLA2G4A,AMOTL1,PCSK1N,TCTN2,ELOVL4,RASAL2,RNF144A,ST14,ZNF311,PLXNA2,MSR1,SPATS2L,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,NELL2,TMEM53,ZNF827,SPEG,ZNF438,STARD4,SHF,SCRN1,PDE4D,ATP6AP1L,GAB2,TRDMT1,VNN2,SFXN4,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,PRKCQ,TBC1D16,ATP10D,SNCA,HTR7,IKZF3,PRKCB,TDO2,CCNA1,ZNF704,HPGD,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,COBL,STON2,MID1,DENND5B,WASF3,ANO10,MYO1D,MXI1,IGFBP6,GLIPR1L1,ATP9A,PRSS35,CCNJL,HERC5,GPR180,GABRR2,RGS7,NDFIP2,TPD52L1,PHLDA2,NEDD4,RGS17,SOAT2,AFF2,GPR155,SLC6A15,DYNC2H1,FIG4,SMAD6,SPRY2,SMPDL3A,TMC7,PFKFB4,VAV3,ALDH2,ARHGEF28,ARAP2,SH3BP2,SYNPO2,AGPAT4,CACNA1E,MPP1,PTPN13,ZDHHC15,GUCY1A2,SKAP1,ZIC1,TERT,PLXDC2,MCC,SVIL,MYOM2,LARP1,SLC43A1,MPZL3,EXPH5,MVK,ACSL1,UGT8,KIF5A,HEBP1,UGDH,PTPN21,ACTL8,C20orf194,ANKRD18A,SLC2A13,ABAT,IKZF2,DNER,RBM11,KREMEN1,SLCO3A1,HMCN1,CEP85L,FKBP11,RTN1,ARHGEF10L,ADPRHL1,PPM1E,SIPA1L2,LRRC6,AKAP7,ABI3BP,DLX6,SLC10A7,ANKFN1,POF1B,SLC2A12,CTTN,PTPRE,MYRIP,FANK1,SLIT2,RASGRP1,PDGFRB,LAMP3,TNK2,ATL1,GPM6A,SESN2,SKAP2,CAPN5,JPH1,ROR1,TMEM47,COTL1,SGK2,SERGEF,TMEM132B,HPSE,ITGBL1,NCAM2,NCOA7,TNFSF4,PPARGC1A,APBA2,MAGI2,FRMD5,GPT2,UST,BCL11B,SV2B,MOCOS,FN1,SEC24D,STXBP6,FBXO4,ELOVL7,YPEL2,LAMC3,GALNT13,CHSY1,FAM81A,SPINK5,SATB1,FAM107B,LIMCH1,NCEH1,CAND2,NOS3,ZNF629,CDH26,GPR176,PCDH10,PARD3B,EDEM3,WWC1,LHPP,B4GALNT3,SLC46A3,HERPUD1,KIAA0355,FAT1,HK2,RAI14,RAB31,TMEM117,NXPH4,PTPRN2,OSBPL6,XKR4,DIRC2,CREB3L2,CXCR5,DMXL2,EML5,ZSWIM5,SORBS1,CELSR3,PLEKHA5,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,PIBF1,UBTD2,DOCK2,SP8,SCIN,CD53,COL22A1,PDZD8,SETDB2,UNC13B,KAZN,PPFIBP1,REEP1,ZNF521,MAP7,ACVR2A,FHIT,GULP1,PROS1,MDH1B,MET,TMEM120B,NTNG1,DPP10,ANTXR2,PRAME,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,TPK1,WARS,BCL11A,ARMC4,LMLN,BACH2,KPNA3,RBPMS2,TMPRSS9,SOHLH2,DISP1,RNF130,LIFR,MAST1,TNIK,ARHGEF11,TSPAN15,ARL15,CMTM8,LRP4,TNFSF13B,NSUN6,CLSTN2,IGF2BP2,NOTUM,OVOL2,SEL1L3,BMP6,MCU,RAB11FIP5,FSD1,CHN2,GTSF1,DSG2,AFAP1L2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,RBMS2,RIN2,HNF4G,CRIM1,ESRRG,CYTH3,SYBU,OGDHL,GRID1,ASAP3,MEI1,AGAP2,PHACTR2,C3orf70,ZFPM2,GALNT14,NAALADL2,LEPR,MAP1B,RERE,CTIF,ADAMTS17,DPY19L2,ICA1,EDA,MYADM,MPP7,ACER2,MAP2K6,THSD7B,SLC7A5,RPS12,KIF21A,RNF157,IL9R,MMP16,NPHP1,MAP3K20,SLC16A10,ABCG1 |
| 8.586e-26 | -57.72 | acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_B_cell_leukaemia | 3911 | 560 | 17385 | 1698 |
ARHGAP26,AASS,CNTNAP3,NPM1,STAT5B,CTBP2,CEBPA,CADM2,KIAA1217,SNX9,CA8,SKI,PCDH7,EPDR1,TGFBR3,DNAH6,PPFIA2,PPP2R2B,TMEM37,COG3,CPE,TSHR,MEIS2,DCC,NFIA,FEZ1,PRKAR2B,ABCC2,INTS6,ENPP1,WIPF3,ATP7B,ARHGAP28,ZBTB20,CAB39L,DNHD1,TMEFF2,VASH2,CRYL1,MEF2C,SCN5A,TMEM63C,TJP1,BBS9,TTC30B,SYCP2,KIAA1671,BACE2,APLF,FAM189A1,SRGAP1,CADPS2,ST8SIA1,FIGN,NCAM1,JAM2,GFRA1,FMNL2,CHRM3,SLC37A1,MYO10,STAT4,FASN,FHL2,RYR2,HIP1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,MBNL2,CACHD1,TEX15,SH3GL2,ADAMTS3,CDH17,FBXO27,TRPC3,CDH2,DOCK9,TFCP2L1,BTC,DNM3,TMSB15A,PKP2,ADD2,LCP2,NRXN1,CDS1,TLR3,KMO,CNKSR3,COL25A1,ALDH1L1,FAM155B,ARL4D,JAKMIP3,DNAH5,MYT1,KCNB2,DZANK1,SSH3,KCNH5,ADCY1,WNT11,TTC28,DSP,ASPH,ZNF618,FGFR1,MAGI3,IQCK,IQCH,PDLIM3,WWTR1,LAMB1,INPP4B,RCN3,LRRC27,CCDC148,TMEM132C,ANKRD13B,WDR17,ROBO2,UBAC2,NKAIN2,CBS,CREB5,EPHB1,TSPAN17,BEX2,COL27A1,GAS2L3,MYO6,C15orf41,MED12L,ULBP1,TRPM4,MCF2L2,AK4,RASA3,ATP11A,SNTB1,GALNT3,PCDHB7,PLOD2,NEK11,HK1,DCBLD1,CRISPLD1,FOXA1,BTRC,PHC1,TLL2,PHACTR3,CACNG3,FGF13,FHDC1,LILRB1,ITPR2,FSTL5,PLS3,CPVL,KCNN2,HPS1,MARVELD2,TMEM143,MPPED2,COL19A1,LIN7A,JAKMIP2,TMEM132E,TLN2,ETV1,NEB,RAPGEF5,ZNF391,DBN1,MARK1,ABCC4,COL4A3,ANK2,GDPD1,SESN1,PLEKHB1,INSIG1,KLF12,MAP2,TIGD4,MLLT3,HS6ST3,RRAGD,LONRF1,UBASH3B,SETBP1,ZNF215,PGAP1,FHOD3,NUMBL,GALNT1,IGF1R,ABCA5,BCHE,GATA2,FRAS1,SAMD11,HS3ST5,PAK1,FGFR4,DPYSL5,CHSY3,UNC5C,SLC27A2,OBSCN,SDK1,KHDRBS2,LDHD,NEGR1,MAPKAPK2,GRIK4,MFSD2A,PLD1,SEMA3A,MME,SFN,CFH,DOCK1,RBFOX2,NTRK3,SEZ6L2,KIF21B,RADIL,PPP1R9A,CBLN1,PCLO,TACC2,CLVS2,IGFBP3,INTU,TMEM65,THSD4,FGF12,FRK,RANBP2,NRG3,PTPRJ,PTPRS,MAOA,TTC39A,CTNND2,CNTN1,MAN2B2,TENM1,PCDH18,NECAB2,BMPR2,GRB14,MCTP2,GABRG2,USP30,SLC35F1,TFAP2A,GTF2F2,PRICKLE2,SYK,KIAA1211,ATP2B1,DLGAP1,MICAL2,PRICKLE1,FERMT2,PALLD,EXOG,EBF1,DOCK7,FAT4,FBN1,L3MBTL4,SH3BGRL2,PAX9,CACNA2D1,C2orf27A,FAM171B,CGN,ACVR1,PPP4R4,LGR4,DUSP8,ATP8A1,HECTD2,ZFYVE28,SLC16A2,ATRNL1,VWA5A,TBC1D8,GLDC,GDAP1,EML6,WISP3,NR6A1,ACVR1C,KLHL4,LRMP,DNAJC6,TNS1,ZDHHC14,ARHGEF26,GPC6,GNAI1,AHRR,NCKAP1L,ENPP6,SH3RF1,RASGRF2,CCBE1,BMP1,UNC5B,NRP1,MRC2,EHHADH,CELSR1,FAM124A,TBC1D1,ZHX3,SCN8A,OPHN1,LRRC49,WDFY4,SLC1A3,APBA1,DYNC1I1,MCOLN2,NAV1,RALGPS2,PRKG1,RUNDC3B,CPXM2,GRIP1,MPDZ,SAMD13,PRR16,FAM155A,RIMS2,QSOX1,COL4A4,DCHS1,RAPGEF4,TTC30A,PEX5L,CCDC85A,PLCB1,MMP15,PKN3,LRRIQ3,MPP2,SQLE,SLFN5,FRMPD3,EPHA3,PLA2G4A,AMOTL1,ST14,RNF144A,PLXNA2,TMEM170B,COL14A1,TIAM2,ZNF827,SPEG,NBEA,DAB2IP,MARCKS,PDK1,TMEM43,CYB5R2,NLGN4X,PRKCQ,SATB2,ATP1B1,POPDC3,MAP3K21,BMPR1A,ATG5,CTTNBP2,NR3C2,PURG,MID1,COBL,DENND5B,ANO10,WASF3,MYO1D,GLIPR1L1,ATP9A,PRSS35,CCNJL,GPR180,NDFIP2,SOAT2,AFF2,RALGAPA2,FIG4,DYNC2H1,TBC1D9,GFI1,B4GALT6,TMC7,SLC40A1,SYNPO2,ARHGEF28,PTPN13,CACNA1E,AGPAT4,GUCY1A2,SKAP1,TERT,PLXDC2,SVIL,MYOM2,CERS1,EXPH5,UGT8,UGDH,ANKRD18A,CACNB4,RBM11,DNER,HMCN1,SLCO3A1,CHST10,CEP85L,QPRT,ARHGEF10L,RTN1,SIPA1L2,TRPC1,CTTN,PCOLCE2,FANK1,MYRIP,SLIT2,GPM6A,SKAP2,CAPN5,TMEM47,ROR1,SERGEF,TMEM132B,NCAM2,ITGBL1,NCOA7,OXTR,PPARGC1A,MAGI2,APBA2,FRMD5,MOCOS,SV2B,FN1,RHOBTB1,STXBP6,ELOVL7,LAMC3,CHADL,GALNT13,CHSY1,PHGDH,SPINK5,SLC30A4,ZNF354A,EBF4,LIMCH1,RNF148,NOS3,CDH26,WWC1,LHPP,PRDM1,B4GALNT3,TMEM154,FAT1,NCR3LG1,HK2,PTPRN2,NXPH4,TMEM117,FNBP1L,XKR4,DMXL2,NEK10,COL18A1,HECW2,PIBF1,DOCK2,SCIN,COL22A1,UNC13B,PDZD8,ZNF521,MAP7,ACVR2A,FHIT,PROS1,MET,TMEM120B,PHLDB2,GCA,PTPRU,TES,PTPN6,DOCK5,CENPV,TPK1,ARMC4,BACH2,KPNA3,TMPRSS9,RGS10,SOHLH2,LIFR,TNIK,LRP4,CLSTN2,COL4A5,OVOL2,CUEDC2,SEL1L3,BMP6,MCU,RAB11FIP5,CHN2,PRKCD,DSG2,AFAP1L2,IPCEF1,IQGAP3,PNMA2,RIN2,USP2,CYTH3,GRID1,OGDHL,MEI1,MARS,PHACTR2,NAALADL2,RERE,MAP1B,ADAMTS17,ICA1,TIFA,EDA,MAP2K6,THSD7B,UACA,KIAA0513,KIF21A,MMP16,SLC16A10,ABCG1 |
| 8.586e-26 | -57.72 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | 3911 | 560 | 17385 | 1698 |
ARHGAP26,AASS,CNTNAP3,NPM1,STAT5B,CTBP2,CEBPA,CADM2,KIAA1217,SNX9,CA8,SKI,PCDH7,EPDR1,TGFBR3,DNAH6,PPFIA2,PPP2R2B,TMEM37,COG3,CPE,TSHR,MEIS2,DCC,NFIA,FEZ1,PRKAR2B,ABCC2,INTS6,ENPP1,WIPF3,ATP7B,ARHGAP28,ZBTB20,CAB39L,DNHD1,TMEFF2,VASH2,CRYL1,MEF2C,SCN5A,TMEM63C,TJP1,BBS9,TTC30B,SYCP2,KIAA1671,BACE2,APLF,FAM189A1,SRGAP1,CADPS2,ST8SIA1,FIGN,NCAM1,JAM2,GFRA1,FMNL2,CHRM3,SLC37A1,MYO10,STAT4,FASN,FHL2,RYR2,HIP1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,MBNL2,CACHD1,TEX15,SH3GL2,ADAMTS3,CDH17,FBXO27,TRPC3,CDH2,DOCK9,TFCP2L1,BTC,DNM3,TMSB15A,PKP2,ADD2,LCP2,NRXN1,CDS1,TLR3,KMO,CNKSR3,COL25A1,ALDH1L1,FAM155B,ARL4D,JAKMIP3,DNAH5,MYT1,KCNB2,DZANK1,SSH3,KCNH5,ADCY1,WNT11,TTC28,DSP,ASPH,ZNF618,FGFR1,MAGI3,IQCK,IQCH,PDLIM3,WWTR1,LAMB1,INPP4B,RCN3,LRRC27,CCDC148,TMEM132C,ANKRD13B,WDR17,ROBO2,UBAC2,NKAIN2,CBS,CREB5,EPHB1,TSPAN17,BEX2,COL27A1,GAS2L3,MYO6,C15orf41,MED12L,ULBP1,TRPM4,MCF2L2,AK4,RASA3,ATP11A,SNTB1,GALNT3,PCDHB7,PLOD2,NEK11,HK1,DCBLD1,CRISPLD1,FOXA1,BTRC,PHC1,TLL2,PHACTR3,CACNG3,FGF13,FHDC1,LILRB1,ITPR2,FSTL5,PLS3,CPVL,KCNN2,HPS1,MARVELD2,TMEM143,MPPED2,COL19A1,LIN7A,JAKMIP2,TMEM132E,TLN2,ETV1,NEB,RAPGEF5,ZNF391,DBN1,MARK1,ABCC4,COL4A3,ANK2,GDPD1,SESN1,PLEKHB1,INSIG1,KLF12,MAP2,TIGD4,MLLT3,HS6ST3,RRAGD,LONRF1,UBASH3B,SETBP1,ZNF215,PGAP1,FHOD3,NUMBL,GALNT1,IGF1R,ABCA5,BCHE,GATA2,FRAS1,SAMD11,HS3ST5,PAK1,FGFR4,DPYSL5,CHSY3,UNC5C,SLC27A2,OBSCN,SDK1,KHDRBS2,LDHD,NEGR1,MAPKAPK2,GRIK4,MFSD2A,PLD1,SEMA3A,MME,SFN,CFH,DOCK1,RBFOX2,NTRK3,SEZ6L2,KIF21B,RADIL,PPP1R9A,CBLN1,PCLO,TACC2,CLVS2,IGFBP3,INTU,TMEM65,THSD4,FGF12,FRK,RANBP2,NRG3,PTPRJ,PTPRS,MAOA,TTC39A,CTNND2,CNTN1,MAN2B2,TENM1,PCDH18,NECAB2,BMPR2,GRB14,MCTP2,GABRG2,USP30,SLC35F1,TFAP2A,GTF2F2,PRICKLE2,SYK,KIAA1211,ATP2B1,DLGAP1,MICAL2,PRICKLE1,FERMT2,PALLD,EXOG,EBF1,DOCK7,FAT4,FBN1,L3MBTL4,SH3BGRL2,PAX9,CACNA2D1,C2orf27A,FAM171B,CGN,ACVR1,PPP4R4,LGR4,DUSP8,ATP8A1,HECTD2,ZFYVE28,SLC16A2,ATRNL1,VWA5A,TBC1D8,GLDC,GDAP1,EML6,WISP3,NR6A1,ACVR1C,KLHL4,LRMP,DNAJC6,TNS1,ZDHHC14,ARHGEF26,GPC6,GNAI1,AHRR,NCKAP1L,ENPP6,SH3RF1,RASGRF2,CCBE1,BMP1,UNC5B,NRP1,MRC2,EHHADH,CELSR1,FAM124A,TBC1D1,ZHX3,SCN8A,OPHN1,LRRC49,WDFY4,SLC1A3,APBA1,DYNC1I1,MCOLN2,NAV1,RALGPS2,PRKG1,RUNDC3B,CPXM2,GRIP1,MPDZ,SAMD13,PRR16,FAM155A,RIMS2,QSOX1,COL4A4,DCHS1,RAPGEF4,TTC30A,PEX5L,CCDC85A,PLCB1,MMP15,PKN3,LRRIQ3,MPP2,SQLE,SLFN5,FRMPD3,EPHA3,PLA2G4A,AMOTL1,ST14,RNF144A,PLXNA2,TMEM170B,COL14A1,TIAM2,ZNF827,SPEG,NBEA,DAB2IP,MARCKS,PDK1,TMEM43,CYB5R2,NLGN4X,PRKCQ,SATB2,ATP1B1,POPDC3,MAP3K21,BMPR1A,ATG5,CTTNBP2,NR3C2,PURG,MID1,COBL,DENND5B,ANO10,WASF3,MYO1D,GLIPR1L1,ATP9A,PRSS35,CCNJL,GPR180,NDFIP2,SOAT2,AFF2,RALGAPA2,FIG4,DYNC2H1,TBC1D9,GFI1,B4GALT6,TMC7,SLC40A1,SYNPO2,ARHGEF28,PTPN13,CACNA1E,AGPAT4,GUCY1A2,SKAP1,TERT,PLXDC2,SVIL,MYOM2,CERS1,EXPH5,UGT8,UGDH,ANKRD18A,CACNB4,RBM11,DNER,HMCN1,SLCO3A1,CHST10,CEP85L,QPRT,ARHGEF10L,RTN1,SIPA1L2,TRPC1,CTTN,PCOLCE2,FANK1,MYRIP,SLIT2,GPM6A,SKAP2,CAPN5,TMEM47,ROR1,SERGEF,TMEM132B,NCAM2,ITGBL1,NCOA7,OXTR,PPARGC1A,MAGI2,APBA2,FRMD5,MOCOS,SV2B,FN1,RHOBTB1,STXBP6,ELOVL7,LAMC3,CHADL,GALNT13,CHSY1,PHGDH,SPINK5,SLC30A4,ZNF354A,EBF4,LIMCH1,RNF148,NOS3,CDH26,WWC1,LHPP,PRDM1,B4GALNT3,TMEM154,FAT1,NCR3LG1,HK2,PTPRN2,NXPH4,TMEM117,FNBP1L,XKR4,DMXL2,NEK10,COL18A1,HECW2,PIBF1,DOCK2,SCIN,COL22A1,UNC13B,PDZD8,ZNF521,MAP7,ACVR2A,FHIT,PROS1,MET,TMEM120B,PHLDB2,GCA,PTPRU,TES,PTPN6,DOCK5,CENPV,TPK1,ARMC4,BACH2,KPNA3,TMPRSS9,RGS10,SOHLH2,LIFR,TNIK,LRP4,CLSTN2,COL4A5,OVOL2,CUEDC2,SEL1L3,BMP6,MCU,RAB11FIP5,CHN2,PRKCD,DSG2,AFAP1L2,IPCEF1,IQGAP3,PNMA2,RIN2,USP2,CYTH3,GRID1,OGDHL,MEI1,MARS,PHACTR2,NAALADL2,RERE,MAP1B,ADAMTS17,ICA1,TIFA,EDA,MAP2K6,THSD7B,UACA,KIAA0513,KIF21A,MMP16,SLC16A10,ABCG1 |
| 1.533e-25 | -57.14 | mantle_cell_lymphoma | COSMIC cancer mutations | mantle_cell_lymphoma | 2920 | 446 | 17385 | 1698 |
ARHGAP26,FAM171B,CGN,PPP4R4,FLVCR2,PRSS12,ATP8A1,NPM1,CADM2,PRKCA,KIAA1217,RAC3,DACH2,PCDH7,TRPS1,TGFBR3,ZFYVE28,DNAH6,PPFIA2,FAAH2,FAM168A,CHRDL1,ATRNL1,PPP2R2B,TMEM37,COG3,VWA5A,CPE,PLTP,KLHL29,GLDC,MEIS2,EML6,DCC,NR6A1,KLHL23,TGFA,GJB2,LRRK2,DNAJC6,DEPTOR,MEF2B,TNS1,KCND3,ACVR2B,GPC6,ARHGEF26,AHRR,ATP7B,RASGRF2,ARHGAP28,SEMA3C,DSEL,CAB39L,NRP1,DNHD1,TMEFF2,C12orf77,SPOCK3,CRYL1,SCN5A,MRC2,CELSR1,ZHX3,TBC1D1,SCN8A,GTF2IRD1,SLC1A3,WDFY4,DYNC1I1,MTUS1,MCOLN2,SYCP2,NAV1,RALGPS2,FRY,CNTN4,KIAA1671,FAM189A1,PRELID2,PRKG1,SRGAP1,GRIP1,CPXM2,SLC16A9,TOX,CADPS2,ST8SIA1,FIGN,MOXD1,FAM155A,PRR16,TSPAN9,STXBP1,FMNL2,LRP12,RIMS2,PTCH2,KCNQ3,PLEKHA8,SPATA6,RAPGEF4,RYR2,HIP1,CALCRL,AIG1,ST6GALNAC3,PEX5L,CCDC85A,CDC42BPA,PLCB1,C4orf19,MBNL2,SPATA7,DAGLA,BEX4,CACHD1,RIMKLB,PLEKHH2,SH3GL2,PKN3,ADAMTS3,ISM1,LRRIQ3,MPP2,CDH17,LAPTM4B,TRPC3,CDH2,ACSM3,DOCK9,TFCP2L1,EPHA3,TBKBP1,ZNF516,SPATS2L,COLEC10,DDR1,COL14A1,CDS1,RNF150,ZNF827,CHRNA5,CNKSR3,COL25A1,NBEA,JAKMIP3,DNAH5,MYT1,ANKRD18B,KCNB2,SCN3A,FZD1,DZANK1,SFXN4,NPM3,NKX3-2,KCNH5,PREX1,PYGO1,TTC28,ATP10D,SNCA,DCBLD2,HTR7,IQCK,ARHGAP21,IKZF3,IQCH,GYPC,PDLIM3,WFS1,WWTR1,CCNA1,INPP4B,ZNF704,P4HA1,HPGD,GRB10,BMPR1A,PLD5,KLHL31,CTTNBP2,NR3C2,COBL,HACE1,ANO10,CCDC148,FARP1,MXI1,PLSCR4,TMEM132C,WDR17,ROBO2,FZD8,PLAG1,IPO5,NKAIN2,CBS,PSD3,GPR180,COL27A1,NEO1,LRRC55,GHR,MYO6,SMAD6,C15orf41,MED12L,B4GALT6,TMC7,SYNPO2,RAB6B,AGPAT4,RAPGEF2,PTPN13,AK4,RASA3,ATP11A,CTTNBP2NL,GUCY1A2,TRIB3,RPL12,PLOD2,TERT,PLXDC2,SLCO5A1,SVIL,NEK11,MYOM2,CRISPLD1,OCLN,BTRC,TLL2,EXPH5,MVK,CACNG3,LMCD1,ITPR2,NOVA1,DNER,KREMEN1,SLCO3A1,HMCN1,FSTL5,F3,PLS3,RTN1,ARHGEF10L,ADPRHL1,PPM1E,SIPA1L2,CPVL,ANKFN1,COL19A1,LIN7A,JAKMIP2,PCOLCE2,MYRIP,FANK1,IL1RAP,SLIT2,RASGRP1,PDGFRB,TNK2,GPM6A,SLC3A2,ANK2,NFE2L1,TTC22,TCERG1L,RNF44,SESN1,CRYBG3,EML1,TMEM132B,TCF7L1,INHBC,GPRC5B,KLF12,ITGBL1,NCAM2,MAP2,DLX2,PPARGC1A,MAGI2,MLLT3,FRMD5,HS6ST3,CHMP4C,PCSK5,LONRF1,PRKAA2,BCL11B,MOCOS,STXBP5L,FN1,RHOBTB1,BVES,STXBP6,ELOVL7,LAMC3,CHADL,ZIC2,GALNT13,CHSY1,IL18R1,EFEMP1,KIAA1958,GALNT1,PRTFDC1,ZBTB38,BCHE,FRAS1,HS3ST5,FAM107B,LRP6,LIMCH1,NOS3,CHSY3,GPR176,MID2,UNC5C,PCDH10,PARD3B,WDR25,OBSCN,SLITRK5,WWC1,SDK1,LHPP,B4GALNT3,AMDHD1,NEGR1,TBC1D2,GRIK4,FAT1,RAI14,TMEM117,NXPH4,PTPRN2,PLD1,SEMA3A,OSBPL6,XKR4,MME,SIX2,DMXL2,ZSWIM5,DOCK1,LPCAT2,PLEKHA5,HECW2,BCL6B,TDRKH,OR51B4,KIF21B,RADIL,PPP1R9A,DOCK2,CBLN1,DDX60L,PCLO,TBC1D19,SCIN,COL22A1,PDZD8,UNC13B,TACC2,KAZN,MYO3B,ZNF521,EEPD1,STEAP3,MYH15,GULP1,PROS1,TMEM56,FER,PHLDB2,EVL,TMEM65,TDRD3,THSD4,TTLL7,DOCK5,TPK1,ZNF569,NRG3,PTK7,SOHLH2,MAOA,HGF,CYP2U1,MBOAT2,LIFR,CTNND2,CNTN1,MAST1,TSPAN15,CLSTN2,GABRG2,SELL,COL4A5,FAM174B,SEL1L3,BMP6,PPP2R3A,SLC35F1,FOXP2,TECPR1,CHN2,TSC22D1,GTF2F2,PRICKLE2,AFAP1L2,SH3PXD2B,DLGAP1,RIN2,RAB3B,OGDHL,GRID1,MARS,ZFPM2,GALNT14,NAALADL2,RERE,MKX,CTIF,EBF1,ADAMTS17,DOCK7,FAT4,MPP7,L3MBTL4,NACC2,THSD7B,SLC7A5,UACA,SH3BGRL2,PAX9,RNF157,TBC1D4,MMP16,CACNA2D1,SLC16A10 |
| 4.789e-25 | -56.00 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | 2807 | 431 | 17385 | 1698 |
ARHGAP26,FAM171B,CGN,PPP4R4,FLVCR2,PRSS12,NPM1,CADM2,PRKCA,KIAA1217,RAC3,DACH2,PCDH7,TRPS1,TGFBR3,ZFYVE28,DNAH6,PPFIA2,FAAH2,FAM168A,CHRDL1,ATRNL1,PPP2R2B,TMEM37,COG3,VWA5A,CPE,PLTP,KLHL29,GLDC,MEIS2,EML6,DCC,NR6A1,KLHL23,TGFA,GJB2,LRRK2,DNAJC6,DEPTOR,MEF2B,TNS1,KCND3,ACVR2B,GPC6,ARHGEF26,AHRR,ATP7B,RASGRF2,ARHGAP28,SEMA3C,DSEL,CAB39L,NRP1,DNHD1,TMEFF2,C12orf77,SPOCK3,CRYL1,SCN5A,MRC2,CELSR1,ZHX3,TBC1D1,SCN8A,GTF2IRD1,SLC1A3,WDFY4,DYNC1I1,MTUS1,MCOLN2,SYCP2,NAV1,RALGPS2,CNTN4,KIAA1671,FAM189A1,PRELID2,PRKG1,SRGAP1,GRIP1,CPXM2,SLC16A9,TOX,CADPS2,ST8SIA1,FIGN,MOXD1,FAM155A,PRR16,TSPAN9,STXBP1,FMNL2,RIMS2,PTCH2,KCNQ3,PLEKHA8,SPATA6,RAPGEF4,RYR2,HIP1,CALCRL,AIG1,ST6GALNAC3,PEX5L,CCDC85A,CDC42BPA,PLCB1,C4orf19,MBNL2,SPATA7,BEX4,CACHD1,RIMKLB,PLEKHH2,SH3GL2,PKN3,ADAMTS3,ISM1,LRRIQ3,MPP2,CDH17,LAPTM4B,TRPC3,CDH2,DOCK9,TFCP2L1,EPHA3,TBKBP1,ZNF516,SPATS2L,COLEC10,DDR1,COL14A1,CDS1,RNF150,ZNF827,CHRNA5,CNKSR3,COL25A1,NBEA,JAKMIP3,DNAH5,MYT1,ANKRD18B,KCNB2,SCN3A,FZD1,DZANK1,SFXN4,NPM3,NKX3-2,KCNH5,PREX1,PYGO1,TTC28,ATP10D,SNCA,DCBLD2,HTR7,IQCK,ARHGAP21,IKZF3,IQCH,GYPC,PDLIM3,WFS1,WWTR1,CCNA1,INPP4B,ZNF704,P4HA1,HPGD,GRB10,BMPR1A,KLHL31,CTTNBP2,NR3C2,COBL,HACE1,ANO10,CCDC148,FARP1,MXI1,PLSCR4,TMEM132C,WDR17,ROBO2,PLAG1,IPO5,NKAIN2,CBS,PSD3,GPR180,COL27A1,NEO1,LRRC55,GHR,MYO6,C15orf41,MED12L,B4GALT6,TMC7,SYNPO2,RAB6B,AGPAT4,RAPGEF2,PTPN13,AK4,ATP11A,CTTNBP2NL,GUCY1A2,TRIB3,RPL12,TERT,PLXDC2,SLCO5A1,SVIL,NEK11,MYOM2,CRISPLD1,OCLN,BTRC,TLL2,EXPH5,MVK,CACNG3,LMCD1,ITPR2,NOVA1,DNER,KREMEN1,SLCO3A1,HMCN1,FSTL5,F3,PLS3,RTN1,ARHGEF10L,ADPRHL1,PPM1E,SIPA1L2,CPVL,ANKFN1,COL19A1,LIN7A,JAKMIP2,PCOLCE2,MYRIP,FANK1,IL1RAP,SLIT2,RASGRP1,PDGFRB,TNK2,GPM6A,SLC3A2,ANK2,NFE2L1,TCERG1L,RNF44,SESN1,CRYBG3,EML1,TMEM132B,TCF7L1,INHBC,GPRC5B,KLF12,NCAM2,MAP2,DLX2,PPARGC1A,MAGI2,MLLT3,FRMD5,HS6ST3,CHMP4C,LONRF1,PRKAA2,BCL11B,MOCOS,STXBP5L,FN1,RHOBTB1,BVES,STXBP6,ELOVL7,LAMC3,CHADL,ZIC2,GALNT13,CHSY1,IL18R1,EFEMP1,KIAA1958,GALNT1,PRTFDC1,ZBTB38,BCHE,FRAS1,HS3ST5,FAM107B,LRP6,LIMCH1,NOS3,CHSY3,GPR176,MID2,UNC5C,PCDH10,PARD3B,WDR25,OBSCN,SLITRK5,WWC1,SDK1,LHPP,B4GALNT3,AMDHD1,NEGR1,TBC1D2,GRIK4,FAT1,RAI14,TMEM117,NXPH4,PTPRN2,PLD1,SEMA3A,OSBPL6,XKR4,MME,SIX2,DMXL2,ZSWIM5,DOCK1,LPCAT2,PLEKHA5,HECW2,BCL6B,TDRKH,OR51B4,KIF21B,RADIL,PPP1R9A,DOCK2,CBLN1,DDX60L,PCLO,TBC1D19,SCIN,COL22A1,PDZD8,UNC13B,TACC2,KAZN,MYO3B,ZNF521,EEPD1,STEAP3,MYH15,PROS1,TMEM56,FER,PHLDB2,EVL,TMEM65,TDRD3,THSD4,TTLL7,DOCK5,TPK1,ZNF569,NRG3,PTK7,SOHLH2,MAOA,HGF,CYP2U1,MBOAT2,LIFR,CTNND2,CNTN1,MAST1,TSPAN15,CLSTN2,GABRG2,SELL,COL4A5,FAM174B,SEL1L3,BMP6,PPP2R3A,SLC35F1,FOXP2,TECPR1,CHN2,TSC22D1,GTF2F2,PRICKLE2,AFAP1L2,SH3PXD2B,DLGAP1,RIN2,RAB3B,GRID1,MARS,ZFPM2,GALNT14,NAALADL2,RERE,MKX,CTIF,EBF1,ADAMTS17,DOCK7,FAT4,MPP7,L3MBTL4,NACC2,THSD7B,SLC7A5,UACA,SH3BGRL2,PAX9,RNF157,TBC1D4,MMP16,CACNA2D1,SLC16A10 |
| 1.195e-24 | -55.08 | cerebellum | COSMIC cancer mutations | cerebellum | 787 | 171 | 17385 | 1698 |
PPP4R4,ACVR1,FGF13,LGR4,PDE1B,SLC2A13,ITPR2,SNX9,DACH2,HMCN1,FSTL5,EYA4,SLC9A7,PCDH7,ABI3BP,PPFIA2,SLC10A7,ANKFN1,ITGB3,MPPED2,LIN7A,CPE,SLIT2,MEIS2,COL4A3,DCC,TGFA,CAP2,ANK2,JPH1,ELMOD1,FEZ1,ZDHHC14,GPC6,GNAI1,ITGBL1,MAP9,NCOA7,SEMA3C,NRP1,TNFSF4,MAGI2,SPOCK3,RUNX2,PTPRD,TBC1D1,SCN8A,ITGA6,OLAH,SETBP1,TJP1,SLC36A4,ZNF215,LRRC49,WDFY4,BBS9,FHOD3,MTUS1,ABLIM1,KIAA1958,CA2,BCHE,PIK3AP1,FAM189A1,PDE10A,PRKG1,SRGAP1,GRIP1,TOX,TSPAN12,FIGN,CHSY3,MID2,BDNF,PARD3B,VLDLR,RAPGEF4,RYR2,HIP1,AIG1,SDK1,PLCB1,NEGR1,PLEKHH2,C1orf21,PTPRN2,SEMA3A,OSBPL6,XKR4,AMPD1,DOCK9,CREB3L2,EPHA3,PLEKHA5,SLC7A2,NRXN1,COL14A1,PPP1R9A,DOCK2,PCLO,CDS1,TBC1D19,KMO,COL25A1,PPFIBP1,MYO3B,DAB2IP,PDE4D,SCN2A,MET,ZNF365,NTNG1,KIAA1549,DPP10,FER,GARS,THSD4,FGF12,PRKCQ,DOCK5,ATP10D,TPK1,NRG3,ANKRD31,TMPRSS9,ITGA2,ABI3,MAOA,RNF130,CTTNBP2,COBL,CTNND2,DENND5B,MYO1D,ROBO2,KLHL13,ATP9A,ARL15,CLSTN2,GABRG2,SELL,NKAIN2,CREB5,EPHB1,RGS7,NEDD4,ARHGAP44,RAB11FIP5,SLC35F1,CHN2,KIAA0319,RALGAPA2,TBC1D9,C15orf41,AGPAT4,SYBU,ATP11A,C3orf70,ZFPM2,PALLD,SKAP1,NAALADL2,MGMT,PTPRC,TERT,NACC2,FBN1,GNAO1,PLXDC2,THSD7B,SLCO5A1 |
| 4.315e-24 | -53.80 | SHH_subtype | COSMIC cancer mutations | SHH_subtype | 668 | 152 | 17385 | 1698 |
PPP4R4,FGF13,LGR4,PDE1B,SLC2A13,ITPR2,SNX9,DACH2,HMCN1,EYA4,SLC9A7,PCDH7,ABI3BP,PPFIA2,SLC10A7,ANKFN1,ITGB3,MPPED2,LIN7A,CPE,SLIT2,MEIS2,COL4A3,DCC,TGFA,CAP2,ANK2,JPH1,ELMOD1,FEZ1,ZDHHC14,GPC6,ITGBL1,MAP9,NCOA7,SEMA3C,TNFSF4,MAGI2,SPOCK3,RUNX2,PTPRD,TBC1D1,SCN8A,ITGA6,OLAH,SETBP1,TJP1,SLC36A4,ZNF215,LRRC49,WDFY4,BBS9,FHOD3,MTUS1,ABLIM1,KIAA1958,CA2,BCHE,PIK3AP1,FAM189A1,PRKG1,SRGAP1,GRIP1,TOX,TSPAN12,FIGN,CHSY3,MID2,BDNF,PARD3B,VLDLR,RAPGEF4,RYR2,HIP1,AIG1,SDK1,PLCB1,PLEKHH2,C1orf21,PTPRN2,SEMA3A,OSBPL6,XKR4,AMPD1,DOCK9,EPHA3,PLEKHA5,SLC7A2,NRXN1,COL14A1,PPP1R9A,PCLO,TBC1D19,KMO,COL25A1,PPFIBP1,MYO3B,DAB2IP,PDE4D,SCN2A,ZNF365,NTNG1,DPP10,FER,THSD4,FGF12,PRKCQ,DOCK5,TPK1,NRG3,ANKRD31,TMPRSS9,ABI3,ITGA2,MAOA,CTTNBP2,COBL,CTNND2,DENND5B,MYO1D,ROBO2,ATP9A,ARL15,CLSTN2,GABRG2,NKAIN2,SELL,CREB5,RGS7,EPHB1,NEDD4,RAB11FIP5,SLC35F1,CHN2,KIAA0319,RALGAPA2,C15orf41,AGPAT4,SYBU,ATP11A,PALLD,C3orf70,SKAP1,NAALADL2,MGMT,PTPRC,TERT,FBN1,GNAO1,PLXDC2,THSD7B,SLCO5A1 |
| 4.758e-24 | -53.70 | WANG_SMARCE1_TARGETS_UP | MSigDB lists | WANG_SMARCE1_TARGETS_UP | 264 | 85 | 17377 | 1707 |
CFH,RNF144A,LPCAT2,GALNT12,LMCD1,GATA3,ADD2,IL13RA1,HMCN1,PCDH7,RTN1,SIPA1L2,FBXO32,SLC22A17,DLX6,DACT1,ITGB3,ZNF521,NAP1L3,GULP1,MARCKS,PROS1,CPE,PERP,FZD1,CD55,SPOCD1,TES,ALDH1L2,GJB2,NLGN4X,ROR1,ATP10D,WARS,ZNF711,GSN,TDO2,RASGRF2,ITGA2,GRB10,DIRAS1,HS3ST3B1,OXTR,UNC5B,LIFR,STON2,LPP,SERINC5,PLSCR4,FN1,BMPR2,IGFBP6,JDP2,ATP9A,PLAG1,PRSS35,TNFRSF19,SEL1L3,KCNC4,PCDHB14,FRY,BACE2,FRAS1,FLRT3,DSG2,GHR,SMTN,ACTA2,PCDH10,PTPN13,MCF2L2,VLDLR,FHL2,MAFB,PLCB1,STEAP1,MAP1B,NEGR1,HEG1,MKX,MATN2,MCC,PGM2L1,STOM,TLL2 |
| 1.065e-23 | -52.90 | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | COSMIC cancer mutations | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | 667 | 151 | 17385 | 1698 |
PPP4R4,FGF13,LGR4,PDE1B,SLC2A13,ITPR2,SNX9,DACH2,HMCN1,EYA4,SLC9A7,PCDH7,ABI3BP,PPFIA2,SLC10A7,ANKFN1,ITGB3,MPPED2,LIN7A,CPE,SLIT2,MEIS2,COL4A3,DCC,TGFA,CAP2,ANK2,JPH1,ELMOD1,FEZ1,ZDHHC14,GPC6,ITGBL1,MAP9,NCOA7,SEMA3C,TNFSF4,MAGI2,SPOCK3,RUNX2,PTPRD,TBC1D1,SCN8A,ITGA6,OLAH,SETBP1,TJP1,SLC36A4,ZNF215,LRRC49,WDFY4,BBS9,FHOD3,MTUS1,ABLIM1,KIAA1958,CA2,BCHE,PIK3AP1,FAM189A1,PRKG1,SRGAP1,GRIP1,TOX,TSPAN12,FIGN,CHSY3,MID2,BDNF,PARD3B,VLDLR,RAPGEF4,RYR2,HIP1,AIG1,SDK1,PLCB1,PLEKHH2,C1orf21,PTPRN2,SEMA3A,OSBPL6,XKR4,AMPD1,DOCK9,EPHA3,PLEKHA5,SLC7A2,NRXN1,COL14A1,PPP1R9A,PCLO,TBC1D19,KMO,COL25A1,PPFIBP1,MYO3B,DAB2IP,PDE4D,SCN2A,ZNF365,NTNG1,DPP10,FER,THSD4,FGF12,PRKCQ,DOCK5,TPK1,NRG3,ANKRD31,TMPRSS9,ABI3,ITGA2,MAOA,CTTNBP2,COBL,CTNND2,DENND5B,MYO1D,ROBO2,ATP9A,ARL15,CLSTN2,GABRG2,NKAIN2,SELL,CREB5,RGS7,EPHB1,NEDD4,RAB11FIP5,SLC35F1,CHN2,KIAA0319,RALGAPA2,C15orf41,AGPAT4,SYBU,ATP11A,PALLD,C3orf70,SKAP1,NAALADL2,MGMT,PTPRC,FBN1,GNAO1,PLXDC2,THSD7B,SLCO5A1 |
| 7.710e-23 | -50.92 | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MSigDB lists | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 1016 | 200 | 17377 | 1707 |
GXYLT2,SIDT1,FLVCR2,PDE1B,PRSS12,FHDC1,ASS1,NDRG2,ABAT,MGAT5B,SYT14,KIAA1217,BCAN,EYA4,F3,BAG3,CPNE2,PMAIP1,KCNS3,SERINC2,LIN7A,COL19A1,TMEM37,PLTP,GLDC,SKAP2,GJB2,ROR1,TCERG1L,ARHGEF26,GPR150,TSKU,ENPP1,CCBE1,RASGRF2,ATP7B,ARHGAP28,SEMA3C,DLX2,OXTR,SPRY4,UNC5B,TPM1,VASH2,NEUROG2,TC2N,SCN5A,MOCOS,FN1,LGALS3,BVES,STXBP6,LAMC3,ZIC2,SLC1A3,SATB1,PRRG4,GAS1,MECOM,MTUS1,PIK3AP1,GATA2,BACE2,PDE10A,ZIC5,EBF4,HS3ST5,PRKG1,SLC16A9,TSPAN12,LOXL4,SLCO4C1,FIGN,MOXD1,GLIS1,GFRA1,RNF152,SNX7,DPYSL5,PTCH2,IL17RD,BDNF,DISC1,SLC27A2,MYO10,MAFB,PDE8A,SHISA2,PRDM1,C4orf19,HEYL,MFSD2A,EMILIN2,HK2,NXPH4,TESC,CSRP2,EPHA3,TFCP2L1,NBL1,DOCK1,ST14,LPCAT2,PSTPIP2,GALNT6,OTX1,COL18A1,PKP2,SLC7A2,CBLN1,SP8,SCIN,UNC13B,CHRNA5,CNKSR3,GULP1,PROS1,SYNGR3,HSPA2,DOCK8,PERP,DPP10,PHLDB2,ANTXR2,PTPRU,TES,SLC39A8,SOX21,PRKCQ,VIM,WNT11,ATF3,SATB2,ATP1B1,DOCK5,GJC1,BATF3,HTR7,NRG3,POPDC3,GYPC,RBPMS2,EIF4EBP1,LAMB1,CCNA1,WWTR1,RGS10,HS3ST3B1,PLD5,KCTD1,MAST1,TSPAN15,PLAG1,BIK,CMTM8,CBS,PRDM8,IGF2BP2,NOTUM,OVOL2,P2RY1,PHLDA2,BMP6,COL27A1,KCNJ4,DSG2,AFAP1L2,RRAS2,SMAD6,ZFP36L2,MSX1,RAB3B,LITAF,NUAK2,ASAP3,SNTB1,GALNT14,ZIC1,MKX,ADAMTS17,EBF1,GALNT3,ID3,TIFA,FAT4,L3MBTL4,PLOD2,ACER2,THSD7B,SVIL,UACA,SLCO5A1,LRRK1,SLC1A5,SHOX2,SLC16A10,OCLN,STOM,SLC43A1,TLL2 |
| 1.713e-22 | -50.12 | WONG_ADULT_TISSUE_STEM_MODULE | MSigDB lists | WONG_ADULT_TISSUE_STEM_MODULE | 681 | 151 | 17377 | 1707 |
DUSP8,UGDH,PTPN21,PPFIBP2,GATA3,NDRG2,ENAH,SLCO3A1,F3,PLS3,SKI,FKBP9,BAG3,RCAN3,PACSIN1,THSD1,PRKACB,CYP1B1,SLC3A2,PNRC1,CR2,FGF17,SESN1,AHRR,AK1,HLF,GPRC5B,NCAM2,MAP2,PLK2,ZBTB20,TPM1,MAGI2,MLLT3,LPP,EFNB2,LATS2,FN1,CYP4V2,SCD,PFN2,IL18R1,DDIT4,MCOLN2,NAV1,GATA2,PAIP2B,ADCY6,MPDZ,LIMCH1,PTPRCAP,NCAM1,MOXD1,STXBP1,CEBPD,CAND2,UNC5C,BDNF,RHOQ,STAT4,HOMER2,VLDLR,RYR2,PDE8A,C1R,BEX4,PMEPA1,THBS4,MATN2,RAI14,CDH2,ID1,CELSR3,IL15,PLEKHA5,GPR65,MYO1B,PLXNA2,COL18A1,PPP1R9A,PCLO,ALDOC,ZNF521,MAP7,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,SNX10,HSPA2,GATM,IGFBP3,PHLDB2,ANTXR2,EVL,SLC39A8,TES,ATF3,PRKCQ,RAB38,CD40,TTC28,GABARAPL1,ENTPD1,IQCH,PDLIM3,PRKCB,GBP1,LAMB1,HPGD,DBP,CNTN1,COL9A3,GCAT,LRP4,CMTM8,EPS8,RASD1,TPD52L1,PHLDA2,RAB11FIP5,SCN1B,EIF1,TSC22D1,SLC6A15,CERS4,KLF9,ERRFI1,NPTXR,PCK2,DUSP1,USP2,CRIM1,NR4A1,GRID1,FERMT2,ARHGAP32,CEBPB,TRIB3,DOCK7,MYADM,NACC2,PLXDC2,GEM,DDIT3,CACNA2D1,PKIA,FOXA1,ABCG1,PHC1 |
| 5.366e-22 | -48.98 | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 3607 | 511 | 17385 | 1698 |
ARHGAP26,MYCBP2,CGN,GXYLT2,DUSP8,CNTNAP3,NPM1,ENAH,CTBP2,CADM2,BCAN,PRKCA,KIAA1217,DACH2,EYA4,NOS1AP,SKI,PCDH7,TGFBR3,DNAH6,SLC16A2,PPFIA2,CHRDL1,PPP2R2B,CPE,POU3F3,TBC1D8,MEIS2,DCDC1,DCC,NR6A1,KLHL3,EXOC6B,ALDH1L2,CAP2,KLHL4,GJB2,LRRK2,DNAJC6,LRMP,MEF2B,MSRB3,SLC25A28,TNS1,SAV1,INTS6,GPC6,GNAI1,AHRR,ENPP6,NCKAP1L,PLK2,RASGRF2,ARHGAP28,SEMA3C,MAPK13,DSEL,NRP1,UNC5B,TMEFF2,C12orf77,SPOCK3,CARS,LRFN5,KLF8,SCN5A,TMEM63C,STOX2,MRC2,INPPL1,CELSR1,PTPRD,TBC1D1,SCN8A,GABRB2,DHCR24,OPHN1,SLC25A27,GTF2IRD1,BTBD9,LRRC49,ISYNA1,SLC1A3,WDFY4,APBA1,DYNC1I1,RALGPS2,SLC7A11,FRY,CNTN4,BACE2,FAM189A1,MYC,PRKG1,SRGAP1,OPN3,GRIP1,CPXM2,MPDZ,TOX,CADPS2,LOXL4,DENND1C,FIGN,FAM155A,AGL,GLIS1,PRR16,GFRA1,FMNL2,LRP12,RIMS2,CHRM3,ZNF385A,IGSF3,RNF152,PNP,TBC1D8B,MYO10,COL4A4,SPATA6,ARID5B,RAPGEF4,FHL2,RYR2,SMARCD3,C1R,AIG1,CCDC85A,ZBBX,TAF4B,OR11H4,PLCB1,MBNL2,TMEM74,CACHD1,TEX15,RIMKLB,ADAMTS3,CECR2,MATN2,CLMN,HOXD13,CDH2,AMPD1,PLA2G4A,EPHA3,FRMPD3,AMOTL1,RASAL2,ST14,MYO1B,MSR1,ABHD13,PLXNA2,COL14A1,TIAM2,NELL2,RNF150,SPEG,COL25A1,NBEA,FAM133A,DAB2IP,RTKN2,PDE4D,ARL4D,JAKMIP3,DNAH5,MYT1,SCN3A,DOCK8,C3orf67,GAB2,DZANK1,MYLK3,COL6A2,EBPL,PFKFB2,KCNH5,ADCY1,SATB2,PRKCQ,DSP,ASPH,TBC1D16,ATP10D,FGFR1,ZNF711,IQCK,ARHGAP21,IKZF3,TDO2,WFS1,LAMB1,INPP4B,TNFSF15,NR3C2,COBL,MID1,STON2,PURG,HACE1,DENND5B,ANO10,MYO1D,WDR17,ROBO2,IGFBP6,ATP9A,NKAIN2,PSD3,CBS,KIF5C,EPHB1,ZNF219,RGS7,INPP1,KCNC4,COL27A1,IRX5,SOAT2,GAS2L3,GHR,RALGAPA2,SLC6A15,MYO6,GFI1,MED12L,B4GALT6,MN1,VAV3,SYNPO2,AGPAT4,CACNA1E,MCF2L2,RAPGEF2,PTPN13,ATP11A,CTTNBP2NL,GUCY1A2,SNTB1,HEG1,GALNT3,PTPRC,NSD1,TERT,PLXDC2,AKT3,SVIL,NEK11,GRIN2D,MYOM2,BMP4,HK1,DOCK6,DCBLD1,DDIT3,FOXA1,TLL2,EXPH5,UGT8,CACNG3,KIF5A,PTPN21,ACTL8,FHDC1,C20orf194,SYT14,FAM13A,NOVA1,DNER,SLCO3A1,HMCN1,FSTL5,PLS3,RTN1,ARHGEF10L,LGI2,CYP51A1,SIPA1L2,FKBP9,EOMES,CPVL,SEC16B,KCNAB1,LRRC6,HPS1,ABI3BP,ANKFN1,MPPED2,COL19A1,POF1B,LIN7A,JAKMIP2,CTTN,TLN2,MYRIP,ENO1,ETV1,SLIT2,RASGRP1,PGBD5,DBN1,MARK1,ATF4,SKAP2,ABCC4,COL4A3,CR2,ROR1,COTL1,TCERG1L,TMEM132B,TCF7L1,GPRC5B,NCAM2,MAP2,FAM114A2,TNFRSF1A,PIK3C2B,PPARGC1A,MAGI2,MLLT3,HS6ST3,PCSK5,GPT2,BCL11B,SV2B,FN1,OTOGL,RHOBTB1,UBASH3B,ELOVL7,RIMKLA,CYP4V2,SETBP1,LAMC3,ZIC2,GALNT13,CHSY1,MLC1,PHGDH,SPIRE1,FHOD3,EFEMP1,OTUD1,ZBTB38,IGF1R,ABCA5,GATA2,FRAS1,GAN,LRP6,LIMCH1,SNX7,NOS3,ZNF629,IL17RD,UNC5C,PODXL2,SLC27A2,PARD3B,MGAT4B,TMTC4,EDEM3,OBSCN,SLITRK5,KHDRBS2,TEX9,HERPUD1,NEGR1,GRIK4,FAT1,HK2,SH3BP4,NXPH4,PTPRN2,PLD1,DISP2,SEMA3A,XKR4,TESC,DIRC2,CREB3L2,DMXL2,NEK10,CFH,DOCK1,PLEKHA5,LPCAT2,XYLT1,RHPN2,NTRK3,SLC7A2,SEZ6L2,LPIN3,KIF21B,CANX,FAM110B,PRR7,PPP1R9A,PCLO,TBC1D19,COL22A1,SLC22A17,CDC14B,PPFIBP1,KAZN,FABP6,MYO3B,ZNF521,BCL6,MAP7,ACVR2A,GULP1,PROS1,MDH1B,WWC2,MET,SCN2A,IGFBP3,CTH,RPS13,GLI1,ANTXR2,PRAME,FER,PHLDB2,TMEM67,CSN2,PTPRU,FGF12,FRK,DOCK5,WARS,BCL11A,SMAD3,NRG3,LMLN,BACH2,RNF217,PTK7,TMPRSS9,ITGA2,PTPRS,HGF,SUSD4,LIFR,CTNND2,MAST1,MAN2B2,TENM1,TNIK,PCDH18,COL9A3,KLHL13,ARHGEF11,RUSC2,APBB1,SSX1,CLSTN2,GABRG2,COL4A5,PPP2R3A,RPL34,TECPR1,MAP1A,FUT9,STC2,DSG2,GTF2F2,DLGAP1,HNF4G,LRRIQ1,CRIM1,NR4A1,OGDHL,GRID1,MEI1,PRICKLE1,MARS,ARHGAP32,C3orf70,ZFPM2,NPDC1,GALNT14,TLR6,NAALADL2,MGMT,MAP1B,EBF1,ADAMTS17,DPY19L2,DDAH1,DOCK7,FAT4,FBN1,RND3,ACER2,THSD7B,SH3BGRL2,DLG2,SLC1A5,RNF157,KIF1B,MMP16,NPHP1,CACNA2D1,FILIP1,SNPH |
| 5.366e-22 | -48.98 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 3607 | 511 | 17385 | 1698 |
ARHGAP26,MYCBP2,CGN,GXYLT2,DUSP8,CNTNAP3,NPM1,ENAH,CTBP2,CADM2,BCAN,PRKCA,KIAA1217,DACH2,EYA4,NOS1AP,SKI,PCDH7,TGFBR3,DNAH6,SLC16A2,PPFIA2,CHRDL1,PPP2R2B,CPE,POU3F3,TBC1D8,MEIS2,DCDC1,DCC,NR6A1,KLHL3,EXOC6B,ALDH1L2,CAP2,KLHL4,GJB2,LRRK2,DNAJC6,LRMP,MEF2B,MSRB3,SLC25A28,TNS1,SAV1,INTS6,GPC6,GNAI1,AHRR,ENPP6,NCKAP1L,PLK2,RASGRF2,ARHGAP28,SEMA3C,MAPK13,DSEL,NRP1,UNC5B,TMEFF2,C12orf77,SPOCK3,CARS,LRFN5,KLF8,SCN5A,TMEM63C,STOX2,MRC2,INPPL1,CELSR1,PTPRD,TBC1D1,SCN8A,GABRB2,DHCR24,OPHN1,SLC25A27,GTF2IRD1,BTBD9,LRRC49,ISYNA1,SLC1A3,WDFY4,APBA1,DYNC1I1,RALGPS2,SLC7A11,FRY,CNTN4,BACE2,FAM189A1,MYC,PRKG1,SRGAP1,OPN3,GRIP1,CPXM2,MPDZ,TOX,CADPS2,LOXL4,DENND1C,FIGN,FAM155A,AGL,GLIS1,PRR16,GFRA1,FMNL2,LRP12,RIMS2,CHRM3,ZNF385A,IGSF3,RNF152,PNP,TBC1D8B,MYO10,COL4A4,SPATA6,ARID5B,RAPGEF4,FHL2,RYR2,SMARCD3,C1R,AIG1,CCDC85A,ZBBX,TAF4B,OR11H4,PLCB1,MBNL2,TMEM74,CACHD1,TEX15,RIMKLB,ADAMTS3,CECR2,MATN2,CLMN,HOXD13,CDH2,AMPD1,PLA2G4A,EPHA3,FRMPD3,AMOTL1,RASAL2,ST14,MYO1B,MSR1,ABHD13,PLXNA2,COL14A1,TIAM2,NELL2,RNF150,SPEG,COL25A1,NBEA,FAM133A,DAB2IP,RTKN2,PDE4D,ARL4D,JAKMIP3,DNAH5,MYT1,SCN3A,DOCK8,C3orf67,GAB2,DZANK1,MYLK3,COL6A2,EBPL,PFKFB2,KCNH5,ADCY1,SATB2,PRKCQ,DSP,ASPH,TBC1D16,ATP10D,FGFR1,ZNF711,IQCK,ARHGAP21,IKZF3,TDO2,WFS1,LAMB1,INPP4B,TNFSF15,NR3C2,COBL,MID1,STON2,PURG,HACE1,DENND5B,ANO10,MYO1D,WDR17,ROBO2,IGFBP6,ATP9A,NKAIN2,PSD3,CBS,KIF5C,EPHB1,ZNF219,RGS7,INPP1,KCNC4,COL27A1,IRX5,SOAT2,GAS2L3,GHR,RALGAPA2,SLC6A15,MYO6,GFI1,MED12L,B4GALT6,MN1,VAV3,SYNPO2,AGPAT4,CACNA1E,MCF2L2,RAPGEF2,PTPN13,ATP11A,CTTNBP2NL,GUCY1A2,SNTB1,HEG1,GALNT3,PTPRC,NSD1,TERT,PLXDC2,AKT3,SVIL,NEK11,GRIN2D,MYOM2,BMP4,HK1,DOCK6,DCBLD1,DDIT3,FOXA1,TLL2,EXPH5,UGT8,CACNG3,KIF5A,PTPN21,ACTL8,FHDC1,C20orf194,SYT14,FAM13A,NOVA1,DNER,SLCO3A1,HMCN1,FSTL5,PLS3,RTN1,ARHGEF10L,LGI2,CYP51A1,SIPA1L2,FKBP9,EOMES,CPVL,SEC16B,KCNAB1,LRRC6,HPS1,ABI3BP,ANKFN1,MPPED2,COL19A1,POF1B,LIN7A,JAKMIP2,CTTN,TLN2,MYRIP,ENO1,ETV1,SLIT2,RASGRP1,PGBD5,DBN1,MARK1,ATF4,SKAP2,ABCC4,COL4A3,CR2,ROR1,COTL1,TCERG1L,TMEM132B,TCF7L1,GPRC5B,NCAM2,MAP2,FAM114A2,TNFRSF1A,PIK3C2B,PPARGC1A,MAGI2,MLLT3,HS6ST3,PCSK5,GPT2,BCL11B,SV2B,FN1,OTOGL,RHOBTB1,UBASH3B,ELOVL7,RIMKLA,CYP4V2,SETBP1,LAMC3,ZIC2,GALNT13,CHSY1,MLC1,PHGDH,SPIRE1,FHOD3,EFEMP1,OTUD1,ZBTB38,IGF1R,ABCA5,GATA2,FRAS1,GAN,LRP6,LIMCH1,SNX7,NOS3,ZNF629,IL17RD,UNC5C,PODXL2,SLC27A2,PARD3B,MGAT4B,TMTC4,EDEM3,OBSCN,SLITRK5,KHDRBS2,TEX9,HERPUD1,NEGR1,GRIK4,FAT1,HK2,SH3BP4,NXPH4,PTPRN2,PLD1,DISP2,SEMA3A,XKR4,TESC,DIRC2,CREB3L2,DMXL2,NEK10,CFH,DOCK1,PLEKHA5,LPCAT2,XYLT1,RHPN2,NTRK3,SLC7A2,SEZ6L2,LPIN3,KIF21B,CANX,FAM110B,PRR7,PPP1R9A,PCLO,TBC1D19,COL22A1,SLC22A17,CDC14B,PPFIBP1,KAZN,FABP6,MYO3B,ZNF521,BCL6,MAP7,ACVR2A,GULP1,PROS1,MDH1B,WWC2,MET,SCN2A,IGFBP3,CTH,RPS13,GLI1,ANTXR2,PRAME,FER,PHLDB2,TMEM67,CSN2,PTPRU,FGF12,FRK,DOCK5,WARS,BCL11A,SMAD3,NRG3,LMLN,BACH2,RNF217,PTK7,TMPRSS9,ITGA2,PTPRS,HGF,SUSD4,LIFR,CTNND2,MAST1,MAN2B2,TENM1,TNIK,PCDH18,COL9A3,KLHL13,ARHGEF11,RUSC2,APBB1,SSX1,CLSTN2,GABRG2,COL4A5,PPP2R3A,RPL34,TECPR1,MAP1A,FUT9,STC2,DSG2,GTF2F2,DLGAP1,HNF4G,LRRIQ1,CRIM1,NR4A1,OGDHL,GRID1,MEI1,PRICKLE1,MARS,ARHGAP32,C3orf70,ZFPM2,NPDC1,GALNT14,TLR6,NAALADL2,MGMT,MAP1B,EBF1,ADAMTS17,DPY19L2,DDAH1,DOCK7,FAT4,FBN1,RND3,ACER2,THSD7B,SH3BGRL2,DLG2,SLC1A5,RNF157,KIF1B,MMP16,NPHP1,CACNA2D1,FILIP1,SNPH |
| 6.057e-22 | -48.86 | AACTTT_UNKNOWN | MSigDB lists | AACTTT_UNKNOWN | 1759 | 295 | 17377 | 1707 |
SIDT1,PRSS12,ENAH,ADAMTS6,CTBP2,DOCK3,DACH2,EYA4,HECTD2,PCDH7,TRPS1,CDR2L,CFHR1,PPFIA2,RAP2A,CHRDL1,KCNS3,COG3,PPP2R2B,TSHR,POU3F3,NKX2-1,GLDC,MEIS2,NR6A1,KLHL3,ACVR1C,NFIA,MEF2B,SLC25A28,PRKAR2B,KCND3,SAV1,GPC6,CA13,GNAI1,BMP1,ZBTB20,SERPINI1,TMEFF2,MEF2C,EFNB2,KLF8,SCN5A,INPPL1,SCN8A,SLK,ISYNA1,SLC1A3,APBA1,DYNC1I1,TNFRSF19,MECOM,CHN1,CNTN4,CACNB2,MYC,FLRT3,ZIC5,PRELID2,SREBF1,SRGAP1,ST8SIA1,MOXD1,TSPAN9,MAST4,GFRA1,RNF152,BDNF,PLEKHA8,TBC1D8B,RAPGEF4,VLDLR,PEX5L,ST6GALNAC3,NPC2,PLCB1,MBNL2,SH3GL2,PMEPA1,MPP2,LAPTM4B,BTC,AMOTL1,ELOVL4,GPR65,OTX1,BEGAIN,PLXNA2,GRK6,COLEC10,NRXN1,CDS1,NELL2,ZNF827,COL25A1,DACT1,PDE4D,SERPINH1,MYT1,VNN2,RNF145,SOX21,SHANK2,ATF3,PYGO1,ATOH1,FGFR1,SNCA,ARHGAP21,IKZF3,GYPC,PDLIM3,HS3ST3B1,MAPK10,HOXB9,NR3C2,MID1,RAB30,MXI1,FARP1,ANKRD13B,GCAT,PLAG1,CREB5,EPHB1,ZNF219,COL27A1,ATXN7L1,LRRN1,GHR,SLC6A15,NPTXR,SMAD6,SPRY2,C15orf41,ZFP36L2,MED12L,MN1,ARAP2,CACNA1E,AGPAT4,HOXA1,ZIC1,ID3,NSD1,AKT3,PLXDC2,XBP1,SHOX2,FOXA1,BTRC,ATP2B4,DDIT3,PHACTR3,CACNG3,TRIM2,FGF13,HEBP1,SLC2A13,ABHD4,IKZF2,NOVA1,SLCO3A1,RND2,PPM1E,RPS6KA2,KCNN2,EOMES,TRPC1,COL19A1,HRK,SLC2A12,TMEM132E,ETV1,RAPGEF5,PRKACB,SESN2,JPH1,NFE2L1,ROR1,TMEM47,TCERG1L,SESN1,SERGEF,TSKU,TCF7L1,KLF12,GPRC5B,NCAM2,ITGBL1,GNB4,PPARGC1A,MLLT3,FRMD5,RRAGD,PCSK5,BCL11B,UST,TYRO3,GPR63,PRKAA2,RHOBTB1,CHCHD7,STXBP6,FAM81A,SATB1,PFN2,SPINK5,IL18R1,IGF1R,BCHE,FRAS1,LRP6,ADCY6,PCDH10,MID2,RHOQ,MSTN,EDEM3,SLITRK5,MAFB,PRDM1,NAP1L5,PLAGL1,SH3BP4,NXPH4,RNF122,SEMA3A,OSBPL6,CREB3L2,SORBS1,NTRK3,FAM198B,SEMA6A,CYP26A1,ZNF362,KCTD15,CDC14B,LHX6,ZNF521,BCL6,STEAP3,TDRD3,TMEM65,PRDM13,FGF12,CHRNA6,VIM,BCL11A,ARMC4,SMAD3,MBOAT2,CTNND2,CNTN1,PCDH18,BMPR2,ARHGEF11,REL,CLSTN2,COL4A5,OVOL2,SEL1L3,PPP2R3A,ARHGAP44,RPL34,MCU,NKX6-1,FOXP2,RAB11FIP5,CHN2,FUT9,STC2,TSC22D1,TFAP2A,MARCH3,PCK2,CRIM1,ESRRG,FOXN3,CYTH3,NUAK2,PRICKLE1,ZFPM2,GALNT14,ILDR2,MAP1B,GPR37,EBF1,MAP2K6,DLG2,PAX9,GEM,MMP16,FILIP1 |
| 1.440e-21 | -47.99 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | 480 | 118 | 17377 | 1707 |
CREB3L2,FAM171B,CGN,ACVR1,TCP11L2,TRIM16,AASS,LPCAT2,ATP8A1,MYO1B,LMCD1,COBLL1,IL13RA1,KIAA1217,ABHD4,FAM110B,FAM131B,CDS1,FBXO32,NBEA,GSTM3,GULP1,MARCKS,WWC2,RAB27B,SLIT2,SNAI2,IGFBP3,RWDD2A,DBN1,PHLDB2,CD55,SESN2,PNRC1,TMEM65,EXOC6B,FAM84A,MSRB3,ATP1B1,ATP10D,SMAD3,CAMK2N1,TCF7L1,MAP2,PLK2,LAMB1,WWTR1,NCOA7,AHNAK2,ZNF704,PAM,MAOA,KLF5,PIK3C2B,MBOAT2,MID1,CTNND2,EFNB2,FN1,GRB14,ARL15,YPEL2,PSD3,RASD1,SYDE2,MECOM,DDIT4,ZNF354A,SCN1B,FRAS1,TFAP2A,TSPAN12,LIMCH1,MYO6,ERRFI1,ATP2B1,DUSP1,PARP9,EPB41L5,ARAP2,USP2,GSTM2,KDM5B,CRIM1,RAPGEF2,ARID5B,FHL2,NUAK2,PRICKLE1,FERMT2,PHACTR2,SHISA2,CDC42BPA,PALLD,GUCY1A2,DKK1,GPR37,BEX4,ID3,MYADM,FAT4,FCHO2,PMEPA1,RND3,FBN1,MATN2,SH3BP4,KIAA0513,UACA,PGM2L1,TUFT1,SH3BGRL2,FNBP1L,CDH2,MMP16,DDIT3,MME,ABCG1 |
| 1.561e-21 | -47.91 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | 431 | 110 | 17377 | 1707 |
EPHA3,DNM3,SORBS1,ID1,CFH,IL15,AASS,RBFOX2,GATA3,KCTD12,ENAH,IL13RA1,ABAT,NRXN1,NUP62CL,COL14A1,PCLO,TXNRD3,TUBB4A,CDR2L,PPM1E,RPS6KA2,KCNN2,CDC14B,ALDOC,MAGEA3,BCL6,TMEM143,NAP1L3,MET,MAGEA6,TLN2,HSPA2,CTH,LAMP3,CYP1B1,GLDC,IGFBP3,PGBD5,DZANK1,DBN1,FER,GPM6A,COL6A2,TUBA1A,ATF7IP2,PRKAR2B,EFHC1,TMEM47,COTL1,ATP1B1,FGFR1,GSN,HPSE,ITGBL1,PRKCB,PLK2,CCNA1,MAP9,AHNAK2,RCN3,HPGD,SERPINI1,DLX2,TPM1,LIFR,MEF2C,RPS20,EFNB2,DYRK3,FN1,EHHADH,ITGA6,MLF1,BIK,SSX1,KIF5C,GPSM2,SFXN3,FOXG1,PFN2,PHLDA2,SGK3,RUNDC3B,TSPAN12,TSPAN13,NCAM1,DUSP1,FGFR4,MICAL2,MSX1,ALDH2,KDM5B,NR4A1,MGST3,CRIP2,OGDHL,MAFB,SMARCD3,PLS1,SNAP25,HOXA1,BAIAP2,GLCE,BEX4,FBN1,KIAA0513,TUFT1,HK1,CSRP2 |
| 1.716e-21 | -47.81 | astrocytoma_Grade_III | COSMIC cancer mutations | astrocytoma_Grade_III | 1574 | 269 | 17385 | 1698 |
ARHGAP26,ACVR1,PDE1B,PRSS12,GATA3,CADM2,PRKCA,SLC9A7,PCDH7,TGFBR3,PPFIA2,ATRNL1,THSD1,EML6,DCC,EXOC6B,KLHL4,DEPTOR,ZDHHC14,GPC6,GNAI1,AHRR,SLC7A1,PLK2,ATP7B,BDH2,SEMA3C,TANC2,CRYL1,EFNB2,SCN5A,STOX2,FAM124A,CELSR1,TBC1D1,OPHN1,GTF2IRD1,WDFY4,DYNC1I1,MCOLN2,CHN1,RALGPS2,BACE2,PRELID2,PRKG1,GRIP1,SLC16A9,TOX,CADPS2,SAMD13,MOXD1,FAM155A,GLIS1,PRR16,IGSF3,QSOX1,KCNQ3,TBC1D8B,ARID5B,RAPGEF4,RYR2,SMARCD3,HIP1,ST6GALNAC3,PEX5L,CCDC85A,PLCB1,MBNL2,CACHD1,SH3GL2,ADAMTS3,C1orf21,EMILIN2,CDH17,CDH2,ACSM3,DOCK9,EPHA3,PLA2G4A,ZNF516,RASAL2,MYO1B,PLXNA2,GRK6,LCP2,COL14A1,ZFYVE9,CDS1,ZNF827,EPB41L3,COL25A1,CNKSR3,RTKN2,JAKMIP3,DNAH5,KIAA1549,SCN3A,GARS,NECAB1,SHANK2,FGFR1,ZNF396,PRKCB,TNFSF15,GRB10,KLHL31,CTTNBP2,NR3C2,COBL,STON2,DENND5B,MYO1D,CCDC148,FARP1,ROBO2,IPO5,HERC5,PSD3,NKAIN2,ARL2,EPHB1,NEDD4,LRRN1,MYO6,ULBP1,MN1,VAV3,AGPAT4,MCF2L2,ATP11A,CTTNBP2NL,UCHL3,SNTB1,SKAP1,GPLD1,TERT,PLXDC2,SLCO5A1,GRIN2D,HK1,BTRC,B4GALT7,TLL2,KIF5A,ACTL8,ASS1,FAM13A,DNER,ABHD4,HMCN1,FSTL5,QPRT,RTN1,FKBP9,LRRC6,ABI3BP,MARVELD2,TMEM143,TLN2,OR2W3,MYRIP,NEB,PDGFRB,PGBD5,MARK1,ABCC4,ANK2,JPH1,CR2,SGK2,INSIG1,NCAM2,ITGBL1,PPARGC1A,MAGI2,FRMD5,HS6ST3,BCL11B,STXBP5L,LAMC3,SETBP1,GALNT13,SPINK5,FHOD3,GALNT1,IGF1R,SEMA4F,ABCA5,CHSY3,UNC5C,GPR176,TCEA3,OBSCN,WDR25,SDK1,KHDRBS2,NEGR1,FAT1,PTPRN2,TMEM117,DISP2,SEMA3A,PANK3,XKR4,DIRC2,DOCK1,IL15,PLEKHA5,SEZ6L2,PCLO,DOCK2,PPP1R9A,FAM131B,COL22A1,RPS6KL1,MAP7,MYH15,PROS1,FHIT,MET,TMEM56,GLI1,RPS13,FER,PHLDB2,TMEM67,PTPRU,TES,FGF12,DOCK5,ARMC4,NRG3,PTPRJ,ABI3,SOHLH2,MAOA,TENM1,PCDH18,IL32,BLVRB,MCTP2,CLSTN2,IGF2BP2,CHN2,FUT9,GTF2F2,TRIM3,AFAP1L2,IQGAP3,RRAS2,CRIM1,ESRRG,CYTH3,GRID1,ARHGAP32,ZFPM2,GALNT14,NAALADL2,CTIF,MKX,EBF1,DOCK7,ICA1,FAT4,MAP2K6,THSD7B,TBC1D4,IL9R,CACNA2D1 |
| 7.577e-21 | -46.33 | CTTTGT_V$LEF1_Q2 | MSigDB lists | CTTTGT_V$LEF1_Q2 | 1828 | 300 | 17377 | 1707 |
LANCL3,GRIK2,RECK,ATP8A1,STAT5B,EYA4,PCDH7,CDR2L,RAP2A,CHRDL1,SERINC2,KCNS3,ATRNL1,PPP2R2B,THSD1,POU3F3,NKX2-1,MEIS2,NR6A1,KLHL4,BNIP3L,PRKAR2B,ACVR2B,ZDHHC14,GPC6,PLK2,B3GALT2,SERPINI1,CAB39L,TMOD2,TPM1,MEF2C,EFNB2,KLF8,GABRB2,ST6GAL1,OPHN1,LRRC49,BTBD9,MTUS1,ABLIM1,CNTN4,SLC7A11,FRY,FLRT3,ZIC5,ST8SIA1,MAST4,COL9A2,GFRA1,ZNF385A,GPR161,RNF152,BDNF,TBC1D8B,MYO10,DCHS1,PACSIN3,NPC2,MBNL2,CLN5,PKN3,MPP2,HOXD13,CDH2,NBL1,AMOTL1,OTX1,KCTD12,IL13RA1,DDR1,ZNF827,DACT1,SHF,RTKN2,DAB2IP,MARCKS,PDE4D,MYT1,KCNB2,SCN3A,GAB2,FZD1,PANK1,WNT11,ATP1B1,PYGO1,ATOH1,TTC28,TBC1D16,ZNF711,DBP,HOXB9,NR3C2,MID1,RAB30,MXI1,FARP1,ANKRD13B,IGFBP6,EPS8,BIK,CREB5,PKN1,NEDD4,NEO1,HMGCS1,SOAT2,LRRN1,PCBP4,MCF2L,SGK3,MORN2,SEPT3,SMAD6,SPRY2,C15orf41,FES,MN1,CACNA1E,AGPAT4,CTTNBP2NL,UCHL3,SKAP1,ZIC1,NSD1,PLOD2,AKT3,PCGF2,SLCO5A1,SVIL,GRIN2D,CERS1,SHOX2,FOXA1,BTRC,ATP1A3,PHACTR3,KIF5A,PTPN21,NDRG2,IKZF2,HMCN1,KREMEN1,CHST10,FSTL5,CCNJ,RTN1,TUBB4A,EOMES,AKAP7,SLC10A7,MPPED2,SLC2A12,ETV1,CYP1B1,GPM6A,ATF4,GCNT2,PNRC1,SKAP2,ANK2,GDPD1,ZNF565,ROR1,TMEM47,RNF44,TSKU,TCF7L1,GSN,KLF12,GPRC5B,MAP2,PPARGC1A,FRMD5,RRAGD,UST,BCL11B,RHOBTB1,ZCCHC24,STXBP6,RASL11B,SETBP1,SCD,FAM81A,PFN2,SATB1,PGAP1,DDIT4,HSPA12B,NUMBL,PRTFDC1,IGF1R,GATA2,BCHE,FRAS1,PDE10A,LRP6,BNIP3,NIPAL2,MORN4,BARX1,LRP3,CKAP4,DPYSL5,PAK1,NDUFA4L2,RHOQ,SLITRK2,MSTN,RNF170,MAFB,SLITRK5,HERPUD1,SLC2A6,SEMA3A,NKX2-8,RNF122,FNBP1L,PANK3,OSBPL6,SFN,RBFOX2,RNF24,FAM198B,SEZ6L2,FAM110B,CBLN1,SEMA6A,CTNNA2,ZNF362,COL22A1,KCTD15,TACC2,REEP1,LHX6,BCL6,ZNF521,ACVR2A,MET,SEMA6C,GLI1,TMEM67,TUBA1A,SLC39A8,TES,PRDM13,VIM,JAM3,BCL11A,ZNF569,SMAD3,PTPRJ,BACH2,PTK7,ITGA2,MBOAT2,HEY1,PCDH18,BMPR2,CMTM8,GABRG2,SEL1L3,PPP2R3A,RPL34,FOXP2,CHN2,GTSF1,DSG2,STC2,TSC22D1,TFAP2A,TRIM3,PRICKLE2,MARCH3,TSPAN13,DUSP1,RIN2,MSX1,CRIM1,FOXN3,ESRRG,CRIP2,PRRG1,ZFPM2,LRAT,NAALADL2,MAP1B,DKK1,RERE,DOCK7,RND3,PRCP,MAP2K6,KIF21A,THAP10,MMP16,KIF1B,CACNA2D1,PKIA |
| 7.881e-21 | -46.29 | central_nervous_system-brain-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_III | 1449 | 251 | 17385 | 1698 |
ARHGAP26,PDE1B,PRSS12,KIF5A,ACTL8,ASS1,GATA3,CADM2,FAM13A,PRKCA,ABHD4,DNER,HMCN1,FSTL5,SLC9A7,PCDH7,QPRT,RTN1,FKBP9,TGFBR3,LRRC6,ABI3BP,MARVELD2,PPFIA2,ATRNL1,TLN2,MYRIP,OR2W3,NEB,PDGFRB,PGBD5,MARK1,EML6,ABCC4,DCC,EXOC6B,ANK2,KLHL4,JPH1,DEPTOR,CR2,SGK2,ZDHHC14,GPC6,GNAI1,SLC7A1,INSIG1,ITGBL1,NCAM2,PLK2,ATP7B,BDH2,SEMA3C,TANC2,PPARGC1A,MAGI2,FRMD5,HS6ST3,CRYL1,EFNB2,BCL11B,FAM124A,CELSR1,STXBP5L,TBC1D1,OPHN1,GTF2IRD1,SETBP1,LAMC3,GALNT13,WDFY4,DYNC1I1,FHOD3,MCOLN2,CHN1,GALNT1,RALGPS2,SEMA4F,IGF1R,ABCA5,BACE2,PRELID2,PRKG1,GRIP1,SLC16A9,TOX,CADPS2,SAMD13,MOXD1,FAM155A,PRR16,GLIS1,CHSY3,GPR176,UNC5C,QSOX1,KCNQ3,TBC1D8B,ARID5B,RAPGEF4,TCEA3,WDR25,RYR2,SMARCD3,OBSCN,HIP1,ST6GALNAC3,PEX5L,CCDC85A,SDK1,PLCB1,MBNL2,KHDRBS2,NEGR1,CACHD1,SH3GL2,ADAMTS3,FAT1,C1orf21,EMILIN2,CDH17,TMEM117,PTPRN2,DISP2,SEMA3A,CDH2,XKR4,PANK3,DIRC2,ACSM3,DOCK9,EPHA3,PLA2G4A,ZNF516,RASAL2,IL15,DOCK1,PLEKHA5,MYO1B,GRK6,LCP2,SEZ6L2,COL14A1,PPP1R9A,DOCK2,PCLO,ZFYVE9,CDS1,FAM131B,ZNF827,EPB41L3,COL22A1,COL25A1,CNKSR3,RPS6KL1,MAP7,RTKN2,MYH15,FHIT,PROS1,MET,JAKMIP3,DNAH5,TMEM56,SCN3A,RPS13,GLI1,PHLDB2,FER,TMEM67,GARS,NECAB1,PTPRU,TES,SHANK2,FGF12,DOCK5,FGFR1,ZNF396,ARMC4,NRG3,PTPRJ,PRKCB,ABI3,MAOA,SOHLH2,TNFSF15,GRB10,CTTNBP2,NR3C2,COBL,DENND5B,TENM1,MYO1D,PCDH18,CCDC148,FARP1,IL32,ROBO2,MCTP2,IPO5,BLVRB,CLSTN2,HERC5,PSD3,NKAIN2,ARL2,IGF2BP2,EPHB1,NEDD4,CHN2,FUT9,GTF2F2,TRIM3,AFAP1L2,MYO6,IQGAP3,RRAS2,ULBP1,MN1,VAV3,CRIM1,AGPAT4,MCF2L2,ESRRG,CYTH3,GRID1,ATP11A,CTTNBP2NL,UCHL3,SNTB1,ZFPM2,SKAP1,GALNT14,NAALADL2,MKX,GPLD1,EBF1,ICA1,DOCK7,FAT4,TERT,PLXDC2,MAP2K6,THSD7B,GRIN2D,HK1,TBC1D4,CACNA2D1,B4GALT7,TLL2 |
| 5.808e-20 | -44.29 | intestinal_adenocarcinoma | COSMIC cancer mutations | intestinal_adenocarcinoma | 7391 | 899 | 17385 | 1698 |
ARHGAP26,THOC5,ADAL,FLVCR2,PDE1B,GRIK2,AASS,CNTNAP3,TUBE1,FAM102B,NPM1,STAT5B,CTBP2,CADM2,BCAN,DOCK3,KIAA1217,ABHD6,EYA4,PCDH7,TXNDC5,BAG3,TGFBR3,IKZF5,DNAH6,PPFIA2,RAP2A,NKX2-1,MEIS2,SMAD9,DCC,KLHL23,LRRK2,NFIA,ELMOD1,FEZ1,ABCC2,KCND3,INTS6,ZNF266,ATP7B,MAP9,ARHGAP28,ERCC5,DIRAS1,INPP5F,ZBTB20,CAB39L,DNHD1,VASH2,CRYL1,CARS,SCN5A,GNG12,LATS2,TMEM63C,CYP2J2,ITGA6,SLC36A4,BTBD9,FOXG1,BBS9,CHN1,SYCP2,BNIP1,FRY,KIAA1671,BACE2,FAM189A1,CACNB2,FLRT3,PRELID2,SRGAP1,TOX,LOXL4,DENND1C,FIGN,NCAM1,ZNF518B,JAM2,AGL,GLIS1,GFRA1,FMNL2,CHRM3,ZNF385A,HMGCR,BDNF,SLC37A1,KCNQ3,MYO10,STAT4,ARID5B,ZNF605,FASN,RYR2,HIP1,CALCRL,PLS1,ZBBX,ARRDC4,SPATA7,DHX32,BEX4,CACHD1,TEX15,TMCO3,SH3GL2,ADAMTS3,QPCTL,EMILIN2,CDH17,CLMN,LAPTM4B,HOXD13,FBXO27,CDH2,TRPC3,DOCK9,TFCP2L1,DNM3,ZNF516,GALNT12,GALNT6,LRRCC1,BEGAIN,PKP2,ADD2,IL13RA1,GRK6,COLEC10,LCP2,NRXN1,RNF150,EPB41L3,TLR3,KMO,COL25A1,DACT1,ALDH1L1,RTKN2,PJA1,FAM155B,RPL26L1,JAKMIP3,DNAH5,KCNB2,SCN3A,DOCK8,FZD1,DZANK1,SSH3,MYLK3,RNF145,NECAB1,EBPL,PFKFB2,KCNH5,TRAM1L1,ADCY1,WNT11,TTC28,DSP,ZNF618,METAP1D,FGFR1,MAGI3,GJC1,IRS2,IQCK,ARHGAP21,GYPC,WFS1,GPR160,PEMT,WWTR1,LAMB1,INPP4B,PAM,PLEKHG1,P4HA1,TNFSF15,FAM149A,PLD5,KLHL31,LRRC27,HOXB9,RAB30,FARP1,TMEM132C,ANKRD13B,WDR17,C1QTNF3,ROBO2,EDA2R,CKAP2,ESRP1,PLAG1,IPO5,PSD3,CBS,SLC12A6,PKN1,EPHB1,COL27A1,NEO1,LRRN1,GHR,MYO6,ZFP36L2,MED12L,PARP9,TRPM4,MN1,MCF2L2,RAPGEF2,SNTB1,HEG1,PTPRC,TRIB3,ID3,NSD1,PLOD2,PLPPR2,GNAO1,OSBPL5,SLCO5A1,NEK11,HK1,DOCK6,ATP2B4,CRISPLD1,BTRC,PHC1,PHACTR3,CACNG3,FGF13,FAM227A,LMCD1,ASS1,LILRB1,MGAT5B,ITPR2,FAM13A,RND2,RUFY4,CPNE2,FKBP9,RPS6KA2,EOMES,CPVL,AADAT,SEC16B,KCNN2,HPS1,MARVELD2,TMEM143,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TMEM132E,ETV1,ENO1,TLR4,NEB,ZNF391,DBN1,ITGB7,SLC3A2,CD55,ABCC4,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TCERG1L,NT5DC2,TSKU,SPNS1,TRIM9,TCF7L1,INHBC,KLF12,MAP2,TECPR2,ERN1,CCDC146,TNFRSF1A,AHNAK2,PIK3C2B,MLLT3,CACUL1,HS6ST3,LONRF1,PRKAA2,KCNV1,RUNX2,STXBP5L,ITPRIP,ZCCHC24,SETBP1,SORBS3,ZNF215,MLC1,SPIRE1,FHOD3,HSPA12B,RNF180,GALNT1,KIAA1958,KIAA0895,ZBTB38,IGF1R,SEMA4F,BCHE,FRAS1,PDE10A,LRP6,ADCY6,BNIP3,SLCO4C1,FAR2,CHSY3,DPYSL5,UNC5C,SLC27A2,HOMER2,SPATA13,PPFIA4,STRADB,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,GPR19,LDHD,NEGR1,GRIK4,KCNK15,SLC2A6,SEMA3A,TESC,MME,CFH,AKAP5,DOCK1,LPCAT2,RNF24,ZNF83,NTRK3,SLC7A2,FAM198B,KIF21B,LPIN3,SEZ6L2,DENND3,FAM110B,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,CYP26A1,ZNF362,SLC22A17,TACC2,MYO3B,EEPD1,MYH15,SCN2A,FAM78B,SNAI2,IGFBP3,GLI1,INTU,TMEM67,EVL,TMEM65,LRRC8B,THSD4,PRDM13,ACO1,CHRNA6,GSTO1,FRK,SMAD3,RANBP2,NRG3,PTPRJ,RNF217,PTK7,GBP1,ITGA2,KCNG1,PTPRS,MAOA,HGF,MBOAT2,ZNF701,CTNND2,CNTN1,MAN2B2,TENM1,COL9A3,PCDH18,DYRK3,BMPR2,KLHL13,GRB14,RUSC2,APBB1,SELL,ARHGAP44,PPP2R3A,SLC35F1,FOXP2,TTC1,TECPR1,MAP1A,PRICKLE2,PCK2,SYK,KIAA1211,ATP2B1,CES3,DLGAP1,MICAL2,LRRIQ1,CRIP2,FERMT2,TGDS,FNDC3A,PALLD,ILDR2,SMPDL3B,EBF1,DOCK7,FAT4,FBN1,L3MBTL4,ZNF808,SH3BGRL2,DLG2,ZNF474,PAX9,THAP10,KIF1B,FILIP1,CACNA2D1,MYCBP2,PPP4R4,ACVR1,LANCL3,TTC39B,ATP8A1,LDLR,PPFIBP2,GATA3,ENAH,PRKCA,AARS,SLC9A7,NCS1,TRPS1,ZFYVE28,SLC16A2,ATRNL1,BEND4,SP140,PACSIN1,VWA5A,THSD1,PLTP,GLDC,EML6,NR6A1,ALDH1L2,TNS1,EFHC1,ACVR2B,ZDHHC14,ARHGEF26,GPC6,AHRR,SFXN1,SH3RF1,ENPP6,NCKAP1L,PLK2,ENTPD7,CCBE1,BMP1,SERPINI1,DSEL,SPRY4,TANC2,UNC5B,LZTS1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,INPPL1,EHHADH,CELSR1,PTPRD,ZHX3,SCN8A,ST6GAL1,GABRB2,DHCR24,OLAH,OPHN1,MRPL22,ISYNA1,TNFRSF10C,WDFY4,APBA1,TNFRSF19,ADSSL1,DYNC1I1,NIPSNAP3B,MECOM,MTUS1,MCOLN2,NAV1,SLC7A11,CNTN4,PDZD7,MYC,VWDE,OPN3,SREBF1,PRKG1,CPXM2,GRIP1,SLC16A9,MPDZ,COL9A2,RIMS2,GPR161,IGSF3,EPB41L5,PTCH2,QSOX1,TBC1D8B,SLC36A1,COL4A4,VLDLR,RAPGEF4,DCHS1,KIAA1324L,TTC30A,PEX5L,CCDC85A,CDC42BPA,PLCB1,FAM162A,TMEM74,DAGLA,XKR9,VPS37D,PMEPA1,ISM1,PELI2,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,IQSEC2,SLFN5,SMYD3,FRMPD3,EPHA3,TBKBP1,NBL1,AMOTL1,PCSK1N,TCTN2,RASAL2,CCDC110,GPR65,ZNF311,OTX1,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,NELL2,ZNF827,SPEG,ASNS,ZNF438,POU5F1B,SHF,SCRN1,NBEA,DAB2IP,NAP1L3,PDE4D,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,PRKCQ,ATOH1,TBC1D16,TRIQK,ATP10D,DCBLD2,ISG20,ZNF396,ZNF711,PRKCB,TDO2,CCNA1,MAP3K21,GRB10,KLF5,BMPR1A,HS3ST3B1,ATG5,CTTNBP2,NR3C2,COBL,STON2,MID1,HACE1,DENND5B,ANO10,WASF3,MYO1D,ATP9A,CCNJL,HERC5,KIF5C,RGS7,GDPD5,NEDD4,HOPX,RASSF8,LRRC55,SOAT2,MGAT1,AFF2,SGK3,RALGAPA2,SLC6A15,ERRFI1,TBC1D9,SPRY2,TMC7,PFKFB4,ARHGEF28,ARAP2,PXN,AGPAT4,CACNA1E,MPP1,PTPN13,ZDHHC15,CTTNBP2NL,GUCY1A2,GPLD1,ZFP62,OR2T33,TERT,MCC,PGM2L1,TUFT1,SVIL,GRIN2D,TNFRSF17,LARP1,EXPH5,MVK,KIF5A,UGDH,PTPN21,ACTL8,C20orf194,ANKRD18A,ABHD4,RBM11,DNER,CACNB4,KREMEN1,HMCN1,F3,ARHGEF10L,LGI2,CYP51A1,SIPA1L2,LRRC6,GRHL1,AKAP7,ABI3BP,DLX6,ANKFN1,CNNM2,SLC2A12,CTTN,PTPRE,MYRIP,OR2W3,IL1RAP,SLIT2,PDGFRB,PRKACB,TNK2,JPH1,ZNF565,ROR1,SGK2,RNF44,TMEM132B,GSN,GPRC5B,HPSE,ITGBL1,FAM114A2,CCDC169,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,BCL11B,SV2B,FN1,OTOGL,SEC24D,BVES,RIMKLA,CYP4V2,LAMC3,CHADL,GALNT13,CHSY1,FAM81A,SPINK5,PHGDH,SATB1,DDIT4,RNF141,OTUD1,ZNF354A,EEF2,FAM107B,LIMCH1,LRP3,CAND2,NOS3,ZNF629,CDH26,GPR176,IL17RD,PCDH10,PODXL2,SLITRK2,PARD3B,EDEM3,WWC1,PRDM1,B4GALNT3,SLC46A3,GLCE,PLAGL1,KIAA0355,CSAG1,FAT1,HK2,TMEM117,PTPRN2,DISP2,OSBPL6,XKR4,DIRC2,DMXL2,EML5,NEK10,CELSR3,PLEKHA5,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,BCL6B,TDRKH,PIBF1,DOCK2,SP8,ZSCAN5A,SCIN,CD53,COL22A1,SETDB2,UNC13B,CDC14B,KAZN,ZNF521,ACVR2A,FHIT,MDH1B,WWC2,MET,POU2F2,TMEM120B,SEMA6C,DPP10,ANTXR2,FER,PTPRU,MVD,TTLL7,DOCK5,WARS,BCL11A,ZNF569,ARMC4,MSC,BACH2,TRIM34,RGS10,RNF130,LIFR,MAST1,OR51B5,PRSS16,TSPAN15,LRP4,CLSTN2,FAM117B,NOTUM,BMP6,SYDE2,FSD1,NKX6-1,KCNJ4,CHN2,DSG2,STC2,EHD3,KIAA0319,ACTA2,TRIM3,AFAP1L2,IPCEF1,IQGAP3,PNMA2,CARD6,CRIM1,ESRRG,CYTH3,SYBU,OGDHL,GRID1,MEI1,MARS,PHACTR2,ARHGAP32,ZFPM2,TLR6,NAALADL2,LEPR,MAP1B,RERE,CTIF,GPR37,DPY19L2,TIFA,ICA1,MFSD9,NACC2,PRCP,THSD7B,SLC7A5,UACA,KIAA0513,KIF21A,RNF157,MMP16,MAP3K20,SLC16A10,ABCG1 |
| 5.808e-20 | -44.29 | stomach-carcinoma-intestinal_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-intestinal_adenocarcinoma | 7391 | 899 | 17385 | 1698 |
ARHGAP26,THOC5,ADAL,FLVCR2,PDE1B,GRIK2,AASS,CNTNAP3,TUBE1,FAM102B,NPM1,STAT5B,CTBP2,CADM2,BCAN,DOCK3,KIAA1217,ABHD6,EYA4,PCDH7,TXNDC5,BAG3,TGFBR3,IKZF5,DNAH6,PPFIA2,RAP2A,NKX2-1,MEIS2,SMAD9,DCC,KLHL23,LRRK2,NFIA,ELMOD1,FEZ1,ABCC2,KCND3,INTS6,ZNF266,ATP7B,MAP9,ARHGAP28,ERCC5,DIRAS1,INPP5F,ZBTB20,CAB39L,DNHD1,VASH2,CRYL1,CARS,SCN5A,GNG12,LATS2,TMEM63C,CYP2J2,ITGA6,SLC36A4,BTBD9,FOXG1,BBS9,CHN1,SYCP2,BNIP1,FRY,KIAA1671,BACE2,FAM189A1,CACNB2,FLRT3,PRELID2,SRGAP1,TOX,LOXL4,DENND1C,FIGN,NCAM1,ZNF518B,JAM2,AGL,GLIS1,GFRA1,FMNL2,CHRM3,ZNF385A,HMGCR,BDNF,SLC37A1,KCNQ3,MYO10,STAT4,ARID5B,ZNF605,FASN,RYR2,HIP1,CALCRL,PLS1,ZBBX,ARRDC4,SPATA7,DHX32,BEX4,CACHD1,TEX15,TMCO3,SH3GL2,ADAMTS3,QPCTL,EMILIN2,CDH17,CLMN,LAPTM4B,HOXD13,FBXO27,CDH2,TRPC3,DOCK9,TFCP2L1,DNM3,ZNF516,GALNT12,GALNT6,LRRCC1,BEGAIN,PKP2,ADD2,IL13RA1,GRK6,COLEC10,LCP2,NRXN1,RNF150,EPB41L3,TLR3,KMO,COL25A1,DACT1,ALDH1L1,RTKN2,PJA1,FAM155B,RPL26L1,JAKMIP3,DNAH5,KCNB2,SCN3A,DOCK8,FZD1,DZANK1,SSH3,MYLK3,RNF145,NECAB1,EBPL,PFKFB2,KCNH5,TRAM1L1,ADCY1,WNT11,TTC28,DSP,ZNF618,METAP1D,FGFR1,MAGI3,GJC1,IRS2,IQCK,ARHGAP21,GYPC,WFS1,GPR160,PEMT,WWTR1,LAMB1,INPP4B,PAM,PLEKHG1,P4HA1,TNFSF15,FAM149A,PLD5,KLHL31,LRRC27,HOXB9,RAB30,FARP1,TMEM132C,ANKRD13B,WDR17,C1QTNF3,ROBO2,EDA2R,CKAP2,ESRP1,PLAG1,IPO5,PSD3,CBS,SLC12A6,PKN1,EPHB1,COL27A1,NEO1,LRRN1,GHR,MYO6,ZFP36L2,MED12L,PARP9,TRPM4,MN1,MCF2L2,RAPGEF2,SNTB1,HEG1,PTPRC,TRIB3,ID3,NSD1,PLOD2,PLPPR2,GNAO1,OSBPL5,SLCO5A1,NEK11,HK1,DOCK6,ATP2B4,CRISPLD1,BTRC,PHC1,PHACTR3,CACNG3,FGF13,FAM227A,LMCD1,ASS1,LILRB1,MGAT5B,ITPR2,FAM13A,RND2,RUFY4,CPNE2,FKBP9,RPS6KA2,EOMES,CPVL,AADAT,SEC16B,KCNN2,HPS1,MARVELD2,TMEM143,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TMEM132E,ETV1,ENO1,TLR4,NEB,ZNF391,DBN1,ITGB7,SLC3A2,CD55,ABCC4,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TCERG1L,NT5DC2,TSKU,SPNS1,TRIM9,TCF7L1,INHBC,KLF12,MAP2,TECPR2,ERN1,CCDC146,TNFRSF1A,AHNAK2,PIK3C2B,MLLT3,CACUL1,HS6ST3,LONRF1,PRKAA2,KCNV1,RUNX2,STXBP5L,ITPRIP,ZCCHC24,SETBP1,SORBS3,ZNF215,MLC1,SPIRE1,FHOD3,HSPA12B,RNF180,GALNT1,KIAA1958,KIAA0895,ZBTB38,IGF1R,SEMA4F,BCHE,FRAS1,PDE10A,LRP6,ADCY6,BNIP3,SLCO4C1,FAR2,CHSY3,DPYSL5,UNC5C,SLC27A2,HOMER2,SPATA13,PPFIA4,STRADB,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,GPR19,LDHD,NEGR1,GRIK4,KCNK15,SLC2A6,SEMA3A,TESC,MME,CFH,AKAP5,DOCK1,LPCAT2,RNF24,ZNF83,NTRK3,SLC7A2,FAM198B,KIF21B,LPIN3,SEZ6L2,DENND3,FAM110B,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,CYP26A1,ZNF362,SLC22A17,TACC2,MYO3B,EEPD1,MYH15,SCN2A,FAM78B,SNAI2,IGFBP3,GLI1,INTU,TMEM67,EVL,TMEM65,LRRC8B,THSD4,PRDM13,ACO1,CHRNA6,GSTO1,FRK,SMAD3,RANBP2,NRG3,PTPRJ,RNF217,PTK7,GBP1,ITGA2,KCNG1,PTPRS,MAOA,HGF,MBOAT2,ZNF701,CTNND2,CNTN1,MAN2B2,TENM1,COL9A3,PCDH18,DYRK3,BMPR2,KLHL13,GRB14,RUSC2,APBB1,SELL,ARHGAP44,PPP2R3A,SLC35F1,FOXP2,TTC1,TECPR1,MAP1A,PRICKLE2,PCK2,SYK,KIAA1211,ATP2B1,CES3,DLGAP1,MICAL2,LRRIQ1,CRIP2,FERMT2,TGDS,FNDC3A,PALLD,ILDR2,SMPDL3B,EBF1,DOCK7,FAT4,FBN1,L3MBTL4,ZNF808,SH3BGRL2,DLG2,ZNF474,PAX9,THAP10,KIF1B,FILIP1,CACNA2D1,MYCBP2,PPP4R4,ACVR1,LANCL3,TTC39B,ATP8A1,LDLR,PPFIBP2,GATA3,ENAH,PRKCA,AARS,SLC9A7,NCS1,TRPS1,ZFYVE28,SLC16A2,ATRNL1,BEND4,SP140,PACSIN1,VWA5A,THSD1,PLTP,GLDC,EML6,NR6A1,ALDH1L2,TNS1,EFHC1,ACVR2B,ZDHHC14,ARHGEF26,GPC6,AHRR,SFXN1,SH3RF1,ENPP6,NCKAP1L,PLK2,ENTPD7,CCBE1,BMP1,SERPINI1,DSEL,SPRY4,TANC2,UNC5B,LZTS1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,INPPL1,EHHADH,CELSR1,PTPRD,ZHX3,SCN8A,ST6GAL1,GABRB2,DHCR24,OLAH,OPHN1,MRPL22,ISYNA1,TNFRSF10C,WDFY4,APBA1,TNFRSF19,ADSSL1,DYNC1I1,NIPSNAP3B,MECOM,MTUS1,MCOLN2,NAV1,SLC7A11,CNTN4,PDZD7,MYC,VWDE,OPN3,SREBF1,PRKG1,CPXM2,GRIP1,SLC16A9,MPDZ,COL9A2,RIMS2,GPR161,IGSF3,EPB41L5,PTCH2,QSOX1,TBC1D8B,SLC36A1,COL4A4,VLDLR,RAPGEF4,DCHS1,KIAA1324L,TTC30A,PEX5L,CCDC85A,CDC42BPA,PLCB1,FAM162A,TMEM74,DAGLA,XKR9,VPS37D,PMEPA1,ISM1,PELI2,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,IQSEC2,SLFN5,SMYD3,FRMPD3,EPHA3,TBKBP1,NBL1,AMOTL1,PCSK1N,TCTN2,RASAL2,CCDC110,GPR65,ZNF311,OTX1,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,NELL2,ZNF827,SPEG,ASNS,ZNF438,POU5F1B,SHF,SCRN1,NBEA,DAB2IP,NAP1L3,PDE4D,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,PRKCQ,ATOH1,TBC1D16,TRIQK,ATP10D,DCBLD2,ISG20,ZNF396,ZNF711,PRKCB,TDO2,CCNA1,MAP3K21,GRB10,KLF5,BMPR1A,HS3ST3B1,ATG5,CTTNBP2,NR3C2,COBL,STON2,MID1,HACE1,DENND5B,ANO10,WASF3,MYO1D,ATP9A,CCNJL,HERC5,KIF5C,RGS7,GDPD5,NEDD4,HOPX,RASSF8,LRRC55,SOAT2,MGAT1,AFF2,SGK3,RALGAPA2,SLC6A15,ERRFI1,TBC1D9,SPRY2,TMC7,PFKFB4,ARHGEF28,ARAP2,PXN,AGPAT4,CACNA1E,MPP1,PTPN13,ZDHHC15,CTTNBP2NL,GUCY1A2,GPLD1,ZFP62,OR2T33,TERT,MCC,PGM2L1,TUFT1,SVIL,GRIN2D,TNFRSF17,LARP1,EXPH5,MVK,KIF5A,UGDH,PTPN21,ACTL8,C20orf194,ANKRD18A,ABHD4,RBM11,DNER,CACNB4,KREMEN1,HMCN1,F3,ARHGEF10L,LGI2,CYP51A1,SIPA1L2,LRRC6,GRHL1,AKAP7,ABI3BP,DLX6,ANKFN1,CNNM2,SLC2A12,CTTN,PTPRE,MYRIP,OR2W3,IL1RAP,SLIT2,PDGFRB,PRKACB,TNK2,JPH1,ZNF565,ROR1,SGK2,RNF44,TMEM132B,GSN,GPRC5B,HPSE,ITGBL1,FAM114A2,CCDC169,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,BCL11B,SV2B,FN1,OTOGL,SEC24D,BVES,RIMKLA,CYP4V2,LAMC3,CHADL,GALNT13,CHSY1,FAM81A,SPINK5,PHGDH,SATB1,DDIT4,RNF141,OTUD1,ZNF354A,EEF2,FAM107B,LIMCH1,LRP3,CAND2,NOS3,ZNF629,CDH26,GPR176,IL17RD,PCDH10,PODXL2,SLITRK2,PARD3B,EDEM3,WWC1,PRDM1,B4GALNT3,SLC46A3,GLCE,PLAGL1,KIAA0355,CSAG1,FAT1,HK2,TMEM117,PTPRN2,DISP2,OSBPL6,XKR4,DIRC2,DMXL2,EML5,NEK10,CELSR3,PLEKHA5,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,BCL6B,TDRKH,PIBF1,DOCK2,SP8,ZSCAN5A,SCIN,CD53,COL22A1,SETDB2,UNC13B,CDC14B,KAZN,ZNF521,ACVR2A,FHIT,MDH1B,WWC2,MET,POU2F2,TMEM120B,SEMA6C,DPP10,ANTXR2,FER,PTPRU,MVD,TTLL7,DOCK5,WARS,BCL11A,ZNF569,ARMC4,MSC,BACH2,TRIM34,RGS10,RNF130,LIFR,MAST1,OR51B5,PRSS16,TSPAN15,LRP4,CLSTN2,FAM117B,NOTUM,BMP6,SYDE2,FSD1,NKX6-1,KCNJ4,CHN2,DSG2,STC2,EHD3,KIAA0319,ACTA2,TRIM3,AFAP1L2,IPCEF1,IQGAP3,PNMA2,CARD6,CRIM1,ESRRG,CYTH3,SYBU,OGDHL,GRID1,MEI1,MARS,PHACTR2,ARHGAP32,ZFPM2,TLR6,NAALADL2,LEPR,MAP1B,RERE,CTIF,GPR37,DPY19L2,TIFA,ICA1,MFSD9,NACC2,PRCP,THSD7B,SLC7A5,UACA,KIAA0513,KIF21A,RNF157,MMP16,MAP3K20,SLC16A10,ABCG1 |
| 7.125e-20 | -44.09 | soft_tissue | COSMIC cancer mutations | soft_tissue | 5964 | 754 | 17385 | 1698 |
ARHGAP26,DOC2A,GXYLT2,GRIK2,AASS,CNTNAP3,PRSS12,RECK,DNAJC3,NPM1,CTBP2,CEBPA,CADM2,CA8,EYA4,SKI,PCDH7,EPDR1,BAG3,TGFBR3,DNAH6,PPFIA2,FAAH2,RAB26,PPP2R2B,TSHR,MEIS2,DCC,KLHL23,TGFA,CAP2,LRRK2,NFIA,ABCC2,ENPP1,WIPF3,ATP7B,ADRB1,ERCC5,INPP5F,CAB39L,DNHD1,CARS,SCN5A,LATS2,TMEM63C,CYP2J2,ITGA6,ZNF25,TJP1,SLC36A4,TTC30B,FRY,KIAA1671,BACE2,FAM189A1,FLRT3,ZIC5,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,ST8SIA1,LOXL4,MOXD1,ZNF518B,JAM2,AGL,GLIS1,STXBP1,FMNL2,HMGCR,SLC37A1,PNP,KCNQ3,MYO10,STAT4,ARID5B,FASN,RYR2,HIP1,SMARCD3,C1R,CLN5,SPATA7,BEX4,TEX15,TMCO3,GSTO2,SH3GL2,ADAMTS3,EMILIN2,CDH17,CDH2,DOCK9,ZNF516,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,RGS20,PKP2,ADD2,GRK6,COLEC10,TLR3,CHRNA5,GPRIN1,KMO,CNKSR3,ALDH1L1,FAM133A,RTKN2,PJA1,FAM155B,DNAH5,MYT1,KIAA1549,KCNB2,SCN3A,DOCK8,FZD1,C3orf67,GARS,COL6A2,GAPDH,NECAB1,NKX3-2,KCNH5,ADCY1,WNT11,TTC28,DSP,ASPH,FGFR1,MAGI3,ENTPD1,WFS1,LAMB1,PAM,PLEKHG1,ALG11,FAM149A,KLHL31,LRRC27,CGB2,CCDC148,FARP1,TMEM132C,WDR17,ROBO2,EDA2R,CD276,ESRP1,UBAC2,NKAIN2,PSD3,CREB5,BEX2,COL27A1,NEO1,GHR,MORN2,MYO6,NPTXR,MED12L,PARP9,MN1,BCL7A,LCA5,CLYBL,MCF2L2,ATP11A,SNTB1,HEG1,GALNT3,PTPRC,ID3,NSD1,PCDHB7,PLOD2,GNAO1,XBP1,SLCO5A1,NEK11,DOCK6,ATP2B4,FOXA1,BTRC,PHC1,PHACTR3,CACNG3,TRIM16,SYT12,FHDC1,LILRB1,ITPR2,FAM13A,NUP62CL,NOVA1,FSTL5,CCNJ,TM9SF2,EOMES,CPVL,SEC16B,HPS1,ITGB3,TMEM143,MPPED2,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TLR4,NEB,MARK1,CD55,ABCC4,PNRC1,COL4A3,SPOCD1,ANK2,CR2,PLEKHA1,TCERG1L,CRYBG3,TSKU,DYRK1B,FHAD1,TCF7L1,KCNMB4,MAP2,P4HA2,GNB4,ERN1,CCDC146,TNFRSF1A,PIK3C2B,NEUROG2,MLLT3,TC2N,HS6ST3,LGALS3,STXBP5L,UBASH3B,ZCCHC24,SETBP1,PFN2,MLC1,PGAP1,DOK5,FHOD3,NUMBL,KIAA1958,KIAA0895,ZBTB38,PRTFDC1,IGF1R,BCHE,ZNF440,FRAS1,PDE10A,GAN,SMTN,LRP6,ADCY6,SLCO4C1,VGLL4,PAK1,FGFR4,CHSY3,DPYSL5,MID2,UNC5C,MGAT4B,EFNA3,TMTC4,SPATA13,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,TEX9,NEGR1,TBC1D2,GRIK4,HEYL,SLC2A6,PLD1,MME,ID1,CFH,DOCK1,XYLT1,RHPN2,ZNF83,NTRK3,SLC7A2,DENND3,RADIL,PCLO,DDX60L,CYP26A1,TBC1D19,FAM131B,SLC22A17,TACC2,MYO3B,BCL6,EEPD1,MYH15,SCN2A,IGFBP3,INTU,CSN2,TMEM65,THSD4,ACO1,FGF12,RNF125,GSTO1,VIM,FBXO36,FRK,C4BPB,SMAD3,RANBP2,NRG3,PTPRJ,PTK7,ITGA2,MAOA,HGF,CTNND2,TENM1,COL9A3,DYRK3,BMPR2,KLHL13,GRB14,RUSC2,MCTP2,RASD1,PRDM8,ARHGAP44,PPP2R3A,SLC35F1,FOXP2,TECPR1,MAP1A,TFAP2A,TSC22D1,SGK1,PRICKLE2,TSPAN13,KIAA0408,SH3PXD2B,KIAA1211,CES3,DLGAP1,LRRIQ1,LITAF,FERMT2,PRICKLE1,FNDC3A,PALLD,NPDC1,MGMT,SMPDL3B,EBF1,DOCK7,FAT4,FBN1,L3MBTL4,FMO4,ZNF474,SLC22A15,TBC1D4,PTGES,CACNA2D1,FAM171B,MYCBP2,CGN,SIDT1,TCP11L2,LGR4,ATP8A1,LDLR,PPFIBP2,GATA3,ENAH,DACH2,RAC3,AARS,HECTD2,SLC9A7,TRPS1,SLC16A2,KCNS3,GSTM3,ATRNL1,BEND4,VWA5A,RCAN3,TBC1D8,GLDC,ERGIC1,EML6,DCDC1,ACVR1C,KLHL4,LRMP,TNS1,EFHC1,ZDHHC14,GPC6,GPR150,AHRR,PLK2,RASGRF2,SEMA3C,MAPK13,DSEL,TANC2,LZTS1,SPOCK3,INPPL1,FAM124A,CELSR1,ALOX5AP,ZHX3,TBC1D1,GABRB2,OPHN1,WDFY4,SLC1A3,APBA1,DYNC1I1,MECOM,MTUS1,NAV1,RALGPS2,PDZD7,MYC,VWDE,OPN3,PRKG1,CPXM2,GRIP1,MPDZ,TSPAN12,RIMS2,IGSF3,EPB41L5,SLC36A1,COL4A4,RAPGEF4,DCHS1,KIAA1324L,TTYH2,TTC30A,PEX5L,CCDC85A,CDC42BPA,PLCB1,TMEM74,DAGLA,VPS37D,PLEKHH2,PMEPA1,CECR2,THBS4,LRRIQ3,DYNC2LI1,SLFN5,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,TCTN2,ELOVL4,RASAL2,RNF144A,ZNF311,PLXNA2,OTX1,MSR1,CHUK,KCTD12,COL14A1,TBC1D30,ZFYVE9,TIAM2,NELL2,ZNF827,SPEG,POU5F1B,SHF,SCRN1,NBEA,GAB2,NLGN4X,SATB2,PRKCQ,ATOH1,PYGO1,TBC1D16,TRIQK,ATP10D,DCBLD2,ZNF711,HTR7,PRKCB,MAP3K21,ZNF704,HPGD,KLF5,HS3ST3B1,NR3C2,PURG,MID1,COBL,HACE1,DENND5B,ANO10,MYO1D,ANKRD13D,GLIPR1L1,ATP9A,EPS8,ARL2,GABRR2,TPD52L1,INPP1,NEDD4,LRRC55,MGAT1,GPR155,RALGAPA2,FIG4,TBC1D9,SMAD6,GFI1,PFKFB4,VAV3,ARHGEF28,ARAP2,SYNPO2,CACNA1E,PTPN13,ZDHHC15,UCHL3,GUCY1A2,SKAP1,GPR137C,ZIC1,CEBPB,ZFP62,TERT,PLXDC2,PGM2L1,GRIN2D,MYOM2,TNFRSF17,OCLN,MVK,ACSL1,KIF5A,SLC2A13,DNER,CACNB4,KREMEN1,HMCN1,FKBP11,RTN1,LGI2,CYP51A1,ARHGEF10L,SIPA1L2,PPM1E,LRRC6,ANKFN1,SLC10A7,POF1B,TRPC1,SLC2A12,PCOLCE2,MYRIP,FANK1,SLIT2,IL1RAP,PDGFRB,CYP1B1,ATL1,GPM6A,SKAP2,CAPN5,JPH1,YAP1,SERGEF,EML1,TMEM132B,GSN,HPSE,ITGBL1,NCAM2,FAM114A2,NCOA7,OXTR,PPARGC1A,TNFSF4,APBA2,MAGI2,FRMD5,UST,BCL11B,MOCOS,FN1,OTOGL,SCART1,CYP4V2,LAMC3,SCD,GALNT13,SPINK5,CD7,SLC30A4,EBF4,FAM107B,LIMCH1,LRP3,NOS3,ZNF629,CDH26,GPR176,HBG2,PCDH10,IL17RD,PODXL2,SLITRK2,SH2D2A,MSTN,PARD3B,EDEM3,SDC3,WWC1,PRDM1,B4GALNT3,TMEM154,FAT1,HK2,TMEM117,PTPRN2,DISP2,OSBPL6,XKR4,CREB3L2,CXCR5,DMXL2,EML5,ZSWIM5,SORBS1,CELSR3,PLEKHA5,HECW2,MORC4,COL18A1,COBLL1,CANX,DOCK2,SCIN,COL22A1,PDZD8,UNC13B,KAZN,PPFIBP1,ZNF521,MAP7,STEAP3,FHIT,MDH1B,WWC2,MET,ZNF460,NTNG1,SEMA6C,SP140L,DPP10,FER,PTPRU,SLC39A8,PTPN6,TES,AMIGO1,DOCK5,CENPV,TPK1,ARMC4,TMPRSS9,DISP1,CYP2U1,PSPH,MAST1,ARHGEF11,CMTM8,LRP4,NSUN6,TNFSF13B,SSX1,CLSTN2,COL4A5,NOTUM,CUEDC2,SEL1L3,MCU,SCN1B,DSG2,KIAA0319,AFAP1L2,DHRS12,IQGAP3,PNMA2,USP2,CRIM1,NR4A1,ESRRG,SYBU,OGDHL,GRID1,ASAP3,MEI1,AGAP2,ZFPM2,GALNT14,NAALADL2,LEPR,MAP1B,RERE,ADAMTS17,ICA1,NACC2,THSD7B,UACA,KIF21A,MMP16,MAP3K20,SLC16A10 |
| 4.795e-19 | -42.18 | ovary-other-neoplasm | COSMIC cancer mutations | ovary-other-neoplasm | 13098 | 1423 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,DSTN,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ZNF25,TJP1,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,SLC19A2,TLR3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,FZD8,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,FHOD3,RNF180,NUMBL,GALNT1,ZNF440,FRAS1,SMTN,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,MAFB,OBSCN,SDK1,KHDRBS2,NEGR1,TBC1D2,GRIK4,KCNK15,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,IGFBP3,INTU,CSN2,TMEM65,LRRC8B,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,HEY1,TENM1,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,DUSP1,LRRIQ1,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,SHF,GATM,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,PURG,STON2,MID1,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,AFF2,GPR155,DYNC2H1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,SVIL,TNFRSF17,CERS1,LARP1,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,TRPC1,CNNM2,MYRIP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,TNFSF4,PPARGC1A,MAGI2,FRMD5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,PLAGL1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,CD40,CENPV,BATF3,BCL11A,ZNF569,CAMK2N1,ARMC4,ZNF93,KPNA3,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,TSPAN15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,OVOL2,FAM174B,SEL1L3,BMP6,SYDE2,MCU,RAB11FIP5,FSD1,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,CARD6,USP2,HNF4G,CRIM1,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,RPS12,RNF157,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,DOCK3,NHP2,CA8,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,LPP,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,FMNL2,LRP12,CHRM3,HMGCR,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,TRPC3,CSRP2,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,LCP2,TXNRD3,CDS1,EPB41L3,CHRNA5,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,WWTR1,INPP4B,PLEKHG1,P4HA1,RCN3,ALG11,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,ABCC4,GDPD1,PLEKHA1,BATF,NT5DC2,PLEKHB1,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,ZCCHC24,UBASH3B,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,KIAA0895,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,PPFIA4,WDR25,PDE8A,TEX9,MAPKAPK2,NAP1L5,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,LPCAT2,XYLT1,LPIN3,SEZ6L2,PCLO,FAM131B,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,RARRES2,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,ITGA2,KCNG1,ABI3,SEPT5,TTC39A,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,ENTPD7,RASGRF2,CCBE1,SEMA3C,UNC5B,TANC2,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,NAV1,KIAA1257,PDZD7,PIK3AP1,RUNDC3B,OPN3,PRELID1,SLC16A9,TSPAN12,SAMD13,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,ZNF827,TMEM53,STARD4,SCRN1,NBEA,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,HTR7,ZNF396,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,EXPH5,MPZL3,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,AKAP7,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,YPEL2,CYP4V2,LAMC3,GALNT13,PHGDH,SATB1,DDIT4,OTUD1,CA2,RPS11,FAM107B,EBF4,BARX1,NOS3,GPR176,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,BCL6B,TDRKH,UBTD2,DOCK2,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,GULP1,MDH1B,MET,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,ESRRG,CYTH3,GRID1,OGDHL,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SLC16A10,STOM,SNPH |
| 1.097e-18 | -41.35 | LIM_MAMMARY_STEM_CELL_UP | MSigDB lists | LIM_MAMMARY_STEM_CELL_UP | 454 | 108 | 17377 | 1707 |
NUDT10,NBL1,AMOTL1,SORBS1,ELOVL4,RECK,PLXNA2,COL18A1,CACNB4,COL14A1,SLCO3A1,EPDR1,PCDH7,PLS3,SKI,BAG3,TGFBR3,ABI3BP,EEPD1,ACVR2A,TRPC1,PROS1,PPP2R2B,SERPINH1,PTPRE,KLHL29,THSD1,SLIT2,SNAI2,IGFBP3,KCNIP3,TES,ALDH1L2,MSRB3,FEZ1,TNS1,VIM,RARRES2,TMEM47,JAM3,DCBLD2,TSKU,SNCA,GJC1,GNAI1,TRIM9,GSN,TCF7L1,GYPC,GNB4,LAMB1,BMP1,RCN3,SEMA3C,OXTR,NRP1,LIFR,MEF2C,PCDH18,IGFBP6,SEC24D,BVES,RUSC2,ITGA6,FZD8,LRP4,SLC1A3,ZNF219,EPHB1,FHOD3,LRRN1,PCBP4,MYC,SMTN,SCARF2,PRICKLE2,ACTA2,MPDZ,TOX,JAM2,COL9A2,CHSY3,PDLIM7,GPR176,IL17RD,MICAL2,MSX1,LCA5,PXN,AGPAT4,DCHS1,GPSM1,TTYH2,PRICKLE1,FERMT2,PRDM1,HEG1,RND3,ISM1,AKT3,ACER2,MATN2,GEM,SLC1A5,OSBPL6,MME,CSRP2,CRISPLD1 |
| 1.553e-18 | -41.01 | system development | biological process | GO:0048731 | 4216 | 555 | 17256 | 1658 |
DOC2A,ARHGAP26,THOC5,PDE1B,RECK,MCOLN3,CEBPA,STAT5B,CHAC1,BCAN,KIAA1217,SKI,BAG3,TGFBR3,RAP2A,RAB26,TSHR,CPE,POU3F3,NKX2-1,MEIS2,SMAD9,DCC,WLS,LRRK2,NFIA,FEZ1,FGF17,ENPP1,ATP7B,TMOD2,INPP5F,TPM1,VASH2,MEF2C,SCN5A,GNG12,STOX2,ITGA6,FOXG1,HPCAL4,CHN1,SYCP2,FRY,FLRT3,ZIC5,TOX,LOXL4,NCAM1,STXBP1,GFRA1,CHRM3,LRP12,ZNF385A,BDNF,ENAM,ARID5B,FASN,FHL2,CALCRL,SMARCD3,RYR2,SNAP25,CLN5,SH3GL2,CDH17,CLMN,SELENOM,HOXD13,CDH2,SHTN1,TFCP2L1,DNM3,ZNF516,PKP2,ADD2,NRXN1,EPB41L3,TLR3,GPRIN1,DACT1,COL25A1,RTKN2,SYNGR3,ZNF365,MYT1,SNX10,PERP,FZD1,SSH3,MYLK3,ADM2,FZD4,NKX3-2,ADCY1,WNT11,DSP,FGFR1,GJC1,IRS2,CXCL10,APELA,WFS1,LAMB1,WWTR1,PAM,DBP,HOXB9,SERINC5,FARP1,ROBO2,FZD8,PLAG1,BIK,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,COL27A1,NEO1,HMGCS1,LRRN1,NPTXR,ZFP36L2,FES,VEGFC,PDLIM7,B9D1,LZTS3,RAPGEF2,AK4,HEG1,PTPRC,ID3,PCDHB7,AKT3,GNAO1,XBP1,BMP4,JHY,SHOX2,FOXA1,BTRC,ATP2B4,FGF13,ASS1,LILRB1,NDRG2,HDGFL3,NRN1,PLS3,RND2,KCNAB1,EOMES,ITGB3,MPPED2,TBC1D32,COL19A1,LIN7A,ETV1,NEB,RAPGEF5,DBN1,ATF4,MARK1,COL4A3,ANK2,NFE2L1,CR2,PLEKHA1,BATF,TSKU,DYRK1B,TCF7L1,INSIG1,MAP2,GNB4,AHNAK2,DLX2,NEUROG2,TYRO3,RUNX2,ZIC2,PGAP1,DOK5,IL18R1,FHOD3,EFEMP1,NUMBL,SEMA4F,GATA2,BCHE,FRAS1,SMTN,LRP6,ADCY6,BNIP3,PAK1,DPYSL5,FGFR4,UNC5C,GPSM1,EFNA3,SLITRK5,MAFB,SDK1,BAIAP2,NEGR1,MAPKAPK2,MFSD2A,HEYL,CSF1,SEMA3A,SIX2,MME,SFN,PRKN,ID1,RBFOX2,NTRK3,PCLO,SEMA6A,CBLN1,PPP1R9A,CTNNA2,RIDA,TACC2,LHX6,MYO3B,BCL6,MYH15,SCN2A,ZNF488,SNAI2,GLI1,INTU,EVL,CSN2,TMEM65,PRDM13,FGF12,VIM,RARRES2,JAM3,SMAD3,NRG3,PTK7,ITGA2,PTPRS,HGF,CTNND2,HEY1,CNTN1,TENM1,COL9A3,PCDH18,DYRK3,BMPR2,APBB1,PRDM8,ARHGAP44,FOXP2,MAP1A,FUT9,TFAP2A,SGK1,SH3PXD2B,PCK2,SYK,SLC45A3,ATP2B1,PCSK6,MICAL2,FOXN3,CRIP2,PRICKLE1,FNDC3A,PALLD,ILDR2,MGMT,MKX,DKK1,DOCK7,FAT4,FBN1,DLG2,MYRF,PAX9,ACVR1,LGR4,LDLR,GATA3,ENAH,ADAMTS6,PRKCA,RAC3,AARS,STK24,NCS1,TRPS1,TYMP,CHRDL1,GSTM3,PACSIN1,KLHL3,MEF2B,EFHC1,AGO4,ACVR2B,SAV1,SFXN1,HLF,NCKAP1L,CCBE1,PLK2,BMP1,SEMA3C,SERPINI1,SPRY4,SPART,UNC5B,NRP1,EFNB2,LRFN5,SEMA6B,INPPL1,CELSR1,PTPRD,GABRB2,MLF1,SCN8A,DHCR24,SLC25A27,OPHN1,SLC1A3,HERC6,APBA1,TNFRSF19,CHD5,MYORG,MECOM,ABLIM1,NAV1,CNTN4,SLC7A11,PDZD7,MYC,PRKG1,SREBF1,GRIP1,TSPAN12,COL9A2,RIMS2,IGSF3,PTCH2,EPB41L5,DISC1,COL4A4,DCHS1,VLDLR,NSD2,PLCB1,DAGLA,CECR2,WDR19,MATN2,DHCR7,EPHA3,NBL1,AMOTL1,ST14,PLXNA2,OTX1,DDR1,SPEG,ASNS,DAB2IP,SERPINH1,GAB2,SOX21,SHANK2,PREX1,NLGN4X,PRKCQ,ATF3,CBY1,SATB2,ATOH1,PYGO1,POPDC3,HPGD,GRB10,KLF5,BMPR1A,ATG5,MAPK10,CTTNBP2,COBL,STON2,WASF3,MYO1D,KIF5C,SELENOP,GDPD5,PHLDA2,NEDD4,ADGRB2,KDM7A,LRRC55,IRX5,AFF2,FIG4,DYNC2H1,ERRFI1,YBX3,SMAD6,GFI1,SPRY2,VAV3,SLC40A1,TMEM126A,HOXA1,ZIC1,GPLD1,CEBPB,TERT,PCGF2,SVIL,TUFT1,GRIN2D,MYOM2,LRRK1,DDIT3,EXPH5,UGT8,KIF5A,ABAT,DNER,GSDME,EPCAM,LRRC6,GRHL1,DLX6,CTTN,SLIT2,IL1RAP,PRKACB,PDGFRB,CYP1B1,ATL1,GPM6A,CEMIP2,JPH1,YAP1,ROR1,EML1,GSN,HPSE,GPRC5B,NCAM2,OXTR,PPARGC1A,APBA2,MAGI2,PCSK5,UST,BCL11B,FN1,BVES,LAMC3,CHSY1,SPINK5,PHGDH,SATB1,ADGRG6,DDIT4,PCDHB14,ZNF354A,CA2,EEF2,BARX1,NOS3,RAX,ATP5IF1,PCDH10,SLITRK2,MSTN,SH2D2A,PRDM1,ADGRB3,RIPOR2,HK2,EGFL7,NKX2-8,CREB3L2,CXCR5,ZSWIM5,IL15,CELSR3,PLEKHA5,ARHGAP22,COL18A1,HECW2,DOCK2,UNC13B,SETDB2,KAZN,ZNF521,ACVR2A,POU2F2,MET,NTNG1,SEMA6C,PTPRU,PTPN6,AMIGO1,TTLL7,BATF3,WARS,BCL11A,ARMC4,MSC,RBPMS2,DISP1,TNIK,LRP4,CMTM8,OVOL2,BMP6,NKX6-1,SCN1B,DSG2,STC2,KIAA0319,TRIM3,ACTA2,TNFRSF11A,MSX1,USP2,KDM5B,CRIM1,NR4A1,SYBU,ZFPM2,LEPR,RERE,MAP1B,EDA,PRCP,CTSV,SLC7A5,NPHP1,MMP16,SNPH |
| 1.904e-18 | -40.80 | multicellular organism development | biological process | GO:0007275 | 4836 | 620 | 17256 | 1658 |
DOC2A,ARHGAP26,THOC5,PDE1B,RECK,MCOLN3,CEBPA,STAT5B,CHAC1,BCAN,KIAA1217,EYA4,SKI,BAG3,TGFBR3,RAP2A,RAB26,TSHR,CPE,POU3F3,NKX2-1,MEIS2,SMAD9,DCC,WLS,LRRK2,NFIA,HACD1,FEZ1,FGF17,ENPP1,WIPF3,ATP7B,TMOD2,INPP5F,TPM1,VASH2,MEF2C,SCN5A,GNG12,STOX2,ITGA6,FOXG1,HPCAL4,CHN1,SYCP2,FRY,FLRT3,ZIC5,TOX,LOXL4,NCAM1,STXBP1,GFRA1,CHRM3,LRP12,ZNF385A,BDNF,ENAM,SPATA6,ARID5B,FASN,FHL2,SMARCD3,CALCRL,RYR2,SHISA2,SNAP25,CLN5,SH3GL2,CDH17,SELENOM,CLMN,HOXD13,SPRED3,CDH2,SHTN1,CSRP2,TFCP2L1,ZNF516,DNM3,PKP2,ADD2,NRXN1,TXNRD3,EPB41L3,TLR3,GPRIN1,DACT1,COL25A1,RTKN2,SYNGR3,MYT1,DNAH5,ZNF365,SNX10,PERP,FZD1,SSH3,MYLK3,ADM2,FZD4,NKX3-2,ADCY1,WNT11,DSP,ASPH,FGFR1,GJC1,IRS2,CXCL10,APELA,WFS1,LAMB1,WWTR1,PAM,DBP,HOXB9,SERINC5,FARP1,EDA2R,ROBO2,FZD8,PLAG1,BIK,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,COL27A1,NEO1,HMGCS1,LRRN1,NPTXR,ZFP36L2,FES,MN1,VEGFC,PDLIM7,B9D1,LZTS3,RAPGEF2,AK4,RACK1,HEG1,PTPRC,ID3,PCDHB7,AKT3,GNAO1,XBP1,BMP4,JHY,SHOX2,FOXA1,BTRC,ATP2B4,PHC1,TLL2,FGF13,LILRB1,ASS1,NDRG2,HDGFL3,NRN1,PLS3,RND2,KCNAB1,EOMES,ITGB3,MPPED2,TBC1D32,COL19A1,LIN7A,ETV1,NEB,RAPGEF5,DBN1,GCNT2,ATF4,MARK1,COL4A3,ANK2,NFE2L1,CR2,PLEKHA1,BATF,PLEKHB1,TSKU,DYRK1B,TCF7L1,INSIG1,MAP2,GNB4,AHNAK2,TNFRSF1A,DLX2,NEUROG2,MLLT3,CHMP4C,TYRO3,RUNX2,ZIC2,PGAP1,DOK5,IL18R1,FHOD3,EFEMP1,NUMBL,SEMA4F,IGF1R,GATA2,BCHE,FRAS1,SMTN,LRP6,ADCY6,BNIP3,SLCO4C1,PAK1,DPYSL5,FGFR4,UNC5C,GPSM1,EFNA3,SLITRK5,MAFB,OBSCN,SDK1,BAIAP2,NEGR1,MAPKAPK2,MFSD2A,HEYL,CSF1,SEMA3A,SIX2,MME,SFN,PRKN,ID1,RBFOX2,NTRK3,RADIL,PCLO,SEMA6A,CBLN1,PPP1R9A,CTNNA2,RIDA,TACC2,LHX6,MYO3B,BCL6,MYH15,SCN2A,ZNF488,SNAI2,GLI1,INTU,EVL,CSN2,TMEM65,PRDM13,FGF12,ACO1,VIM,RARRES2,JAM3,SMAD3,NRG3,PTK7,ITGA2,PTPRS,HGF,CTNND2,HEY1,CNTN1,TENM1,COL9A3,PCDH18,DYRK3,BMPR2,NLRP14,APBB1,MCTP2,GABRG2,PRDM8,PPP2R3A,ARHGAP44,FOXP2,MAP1A,FUT9,TFAP2A,SGK1,SH3PXD2B,PCK2,SYK,SLC45A3,ATP2B1,PCSK6,DUSP1,MICAL2,FOXN3,CRIP2,PRICKLE1,FNDC3A,PALLD,ILDR2,MGMT,MKX,DKK1,EBF1,DOCK7,FAT4,FBN1,DLG2,PAX9,MYRF,ACVR1,LGR4,LDLR,GATA3,ENAH,ADAMTS6,PRKCA,RAC3,AARS,DACH2,STK24,NCS1,TRPS1,TYMP,CHRDL1,GSTM3,PACSIN1,SLC9C1,KLHL3,MEF2B,EFHC1,AGO4,ACVR2B,SAV1,SPATA9,SFXN1,HLF,NCKAP1L,CCBE1,PLK2,BMP1,SEMA3C,SERPINI1,SPRY4,SPART,UNC5B,TANC2,NRP1,EFNB2,LRFN5,SEMA6B,INPPL1,CELSR1,PTPRD,GABRB2,MLF1,SCN8A,DHCR24,SLC25A27,OPHN1,GTF2IRD1,SLC1A3,TNFRSF10C,HERC6,APBA1,TNFRSF19,CHD5,MYORG,MECOM,ABLIM1,NAV1,CNTN4,SLC7A11,PDZD7,MYC,PRELID1,PRKG1,SREBF1,GRIP1,TSPAN12,COL9A2,GPR161,RIMS2,IGSF3,PTCH2,EPB41L5,DISC1,COL4A4,DCHS1,VLDLR,NSD2,PLCB1,DAGLA,MMP15,CECR2,MATN2,WDR19,DYNC2LI1,DHCR7,EPHA3,NBL1,AMOTL1,ST14,GPR65,PLXNA2,OTX1,DDR1,CCDC120,SPEG,ASNS,DAB2IP,SERPINH1,GATM,GAB2,SOX21,SHANK2,PREX1,NLGN4X,ATF3,PRKCQ,CBY1,SATB2,ATOH1,PYGO1,POPDC3,BEX3,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,ATG5,MAPK10,CTTNBP2,COBL,MID1,STON2,WASF3,MYO1D,KIF5C,SELENOP,GDPD5,PHLDA2,NEDD4,ADGRB2,HOPX,KDM7A,LRRC55,IRX5,MGAT1,AFF2,DYNC2H1,FIG4,ERRFI1,YBX3,SMAD6,GFI1,SPRY2,VAV3,SLC40A1,TMEM126A,HOXA1,ZIC1,GPLD1,CEBPB,TERT,PCGF2,SVIL,TUFT1,GRIN2D,MYOM2,LRRK1,TNFRSF17,DDIT3,EXPH5,UGT8,KIF5A,UGDH,ABAT,DNER,RBM11,KREMEN1,GSDME,EPCAM,LRRC6,GRHL1,DLX6,CTTN,EPHB6,SLIT2,IL1RAP,PRKACB,PDGFRB,CYP1B1,ATL1,GPM6A,CEMIP2,JPH1,YAP1,ROR1,EML1,GSN,GPRC5B,HPSE,NCAM2,OXTR,PPARGC1A,MAGI2,APBA2,PCSK5,UST,BCL11B,FN1,SEC24D,BVES,LAMC3,CHSY1,SPINK5,PHGDH,SATB1,ADGRG6,DDIT4,PCDHB14,EEF2,ZNF354A,CA2,EBF4,BARX1,NOS3,ATP5IF1,PCDH10,CDH26,RAX,SLITRK2,MSTN,SH2D2A,PRDM1,RIPOR2,ADGRB3,HK2,EGFL7,NKX2-8,CREB3L2,CXCR5,ZSWIM5,CELSR3,IL15,PLEKHA5,ARHGAP22,COL18A1,HECW2,DOCK2,SP8,KCTD15,UNC13B,SETDB2,KAZN,ZNF521,ACVR2A,POU2F2,MET,NTNG1,SEMA6C,PTPRU,PTPN6,AMIGO1,CD40,TTLL7,BATF3,WARS,BCL11A,ARMC4,MSC,RBPMS2,SOHLH2,DISP1,TNIK,CMTM8,LRP4,OVOL2,BMP6,NKX6-1,SCN1B,DSG2,STC2,KIAA0319,ACTA2,TRIM3,MTURN,TNFRSF11A,MSX1,USP2,KDM5B,CRIM1,NR4A1,SYBU,ZFPM2,LEPR,RERE,MAP1B,DPY19L2,EDA,PRCP,CTSV,SLC7A5,MAP3K20,NPHP1,MMP16,SNPH |
| 2.564e-18 | -40.50 | TTGTTT_V$FOXO4_01 | MSigDB lists | TTGTTT_V$FOXO4_01 | 1908 | 301 | 17377 | 1707 |
ACVR1,TCP11L2,DUSP8,GRIK2,STAT5B,CADM2,HECTD2,NOS1AP,PCDH7,TRPS1,FBXO32,SLC16A2,CHRDL1,KCNS3,NDUFB8,PPP2R2B,TSHR,POU3F3,NKX2-1,MEIS2,KLHL3,NFIA,MSRB3,SLC25A28,FGF17,ZDHHC14,SLC7A1,ENPP6,MAP9,B3GALT2,ZBTB20,CAB39L,NRP1,MEF2C,LPP,LRFN5,KLF8,MRC2,PTPRD,ST6GAL1,TJP1,ISYNA1,APBA1,TNFRSF19,FOXG1,MECOM,CHN1,ABLIM1,RALGPS2,SLC7A11,FRY,FLRT3,ZIC5,ST8SIA1,NCAM1,FIGN,AGL,TSPAN9,MAST4,GFRA1,ENAM,BDNF,PLEKHA8,MGST3,VLDLR,PEX5L,PLCB1,MBNL2,CLN5,DHX32,PKN3,PELI2,C1orf21,SFMBT1,HOXD13,DOCK9,NBL1,NUDT10,ELOVL4,OTX1,PLXNA2,RGS20,IL13RA1,LCP2,SLC19A2,ZFYVE9,GPR15,DACT1,MARCKS,PDE4D,SCN3A,GAB2,DZANK1,SFXN4,NPM3,SOX21,SATB2,ATOH1,DSP,ATP10D,MAGI3,GABARAPL1,ENTPD1,ZNF711,IKZF3,PDLIM3,POPDC3,PAM,KLF5,DBP,MAPK10,HOXB9,NR3C2,RAB30,MXI1,C1QTNF3,IGFBP6,GCAT,PLAG1,BIK,CREB5,SLC12A6,ZNF219,INPP1,NEDD4,NEO1,GHR,PRKG2,MORN2,SMAD6,PFKFB4,BCL7A,SLC40A1,CACNA1E,MCF2L2,ZDHHC15,CTTNBP2NL,GUCY1A2,SKAP1,GPLD1,ZIC1,ID3,NSD1,PLXDC2,AKT3,GNAO1,OSBPL5,NEK11,BMP4,SHOX2,CACNG3,UGT8,FGF13,PTPN21,DNER,NOVA1,IKZF2,HMCN1,KREMEN1,FSTL5,RTN1,CPVL,KCNN2,SLC10A7,POF1B,SLC2A12,EPHB6,TLN2,ETV1,PDGFRB,GPM6A,MARK1,SESN2,PNRC1,EML1,INHBC,INSIG1,KLF12,GNB4,TIGD4,DLX2,PPARGC1A,TNFSF4,APBA2,NEUROG2,MLLT3,FRMD5,HS6ST3,GPR63,BCL11B,TYRO3,RUNX2,ZNF395,FN1,CHCHD7,STXBP6,ZIC2,SORBS3,SATB1,IL18R1,DDIT4,EFEMP1,IGF1R,GATA2,FAM107B,HS3ST5,LRP6,NIPAL2,MORN4,VGLL4,CKAP4,NOS3,DPYSL5,MID2,RHOQ,SLITRK2,HOMER2,MGAT4B,WDR25,SLITRK5,PRDM1,SDK1,NAP1L5,GRIK4,TMEM154,PLD1,SEMA3A,RNF122,DIRC2,CXCR5,NEK10,SORBS1,ID1,MORC4,RNF24,NTRK3,CBLN1,SEMA6A,CYP26A1,ZNF362,CDC14B,BCL6,ZNF521,MAP7,ACVR2A,HSPA2,SEMA6C,GLI1,EVL,TUBA1A,PTPRU,PRDM13,FGF12,SMAD3,MSC,ITGA2,HEY1,PCDH18,DYRK3,BMPR2,KLHL13,MCTP2,CLSTN2,GABRG2,RASD1,PRDM8,COL4A5,PPP2R3A,FOXP2,RAB11FIP5,TECPR1,CHN2,STC2,GTF2F2,TFAP2A,SGK1,MARCH3,TSPAN13,RBMS2,DUSP1,MSX1,USP2,CRIM1,HNF4G,NR4A1,FOXN3,ESRRG,CRIP2,ZFPM2,PALLD,NAALADL2,MAP1B,DEXI,EBF1,DDAH1,FAT4,MAP2K6,DLG2,FILIP1,CACNA2D1,PKIA |
| 5.775e-18 | -39.69 | anatomical structure morphogenesis | biological process | GO:0009653 | 2047 | 311 | 17256 | 1658 |
ACVR1,LGR4,RECK,GATA3,ENAH,PRKCA,RAC3,STK24,EYA4,SKI,TYMP,TGFBR3,RAP2A,PACSIN1,RCAN3,CPE,NKX2-1,KLHL3,DCC,CAP2,WLS,LRRK2,FEZ1,ACVR2B,SAV1,ARHGEF26,NCKAP1L,CCBE1,BMP1,SEMA3C,TMOD2,UNC5B,TMEFF2,NRP1,TPM1,VASH2,MEF2C,EFNB2,LRFN5,SCN5A,INPPL1,CELSR1,ITGA6,OPHN1,SLC1A3,FOXG1,CHN1,SYCP2,ABLIM1,CNTN4,FRY,PDZD7,FLRT3,MYC,TSPAN12,LOXL4,NCAM1,STXBP1,GFRA1,ZNF385A,EPB41L5,BDNF,ENAM,VLDLR,ARID5B,DCHS1,FHL2,SMARCD3,CALCRL,RYR2,NSD2,MMP15,SH3GL2,MATN2,WDR19,HOXD13,CDH2,SHTN1,TFCP2L1,NBL1,AMOTL1,ST14,OTX1,PLXNA2,PKP2,CHUK,NRXN1,DDR1,EPB41L3,DACT1,COL25A1,DAB2IP,SERPINH1,ZNF365,PERP,GAB2,FZD1,MYLK3,ADM2,FZD4,NKX3-2,SHANK2,ADCY1,SATB2,PRKCQ,WNT11,ATOH1,DSP,ASPH,FGFR1,GJC1,IRS2,APELA,LAMB1,WWTR1,PAM,HPGD,KLF5,GRB10,BMPR1A,COBL,FARP1,ROBO2,FZD8,PLAG1,KIF5C,SLC12A6,EPHB1,ZNF219,PHLDA2,COL27A1,NEO1,HOPX,LRRC55,IRX5,LRRN1,DYNC2H1,FIG4,ERRFI1,SMAD6,SPRY2,VEGFC,B9D1,PDLIM7,SLC40A1,VAV3,RACK1,HOXA1,GPLD1,ZIC1,HEG1,CEBPB,ID3,AKT3,XBP1,PCGF2,TUFT1,MYOM2,BMP4,SHOX2,FOXA1,CRISPLD1,BTRC,UGT8,KIF5A,UGDH,EOMES,DLX6,ITGB3,TBC1D32,POF1B,CTTN,ETV1,SLIT2,PDGFRB,PRKACB,CYP1B1,ATL1,ITGB7,GPM6A,CEMIP2,ANK2,NFE2L1,YAP1,PLEKHA1,TSKU,DYRK1B,INSIG1,HPSE,MAP2,AHNAK2,DLX2,MAGI2,PCSK5,BCL11B,TYRO3,RUNX2,FN1,BVES,LAMC3,CHSY1,ADGRG6,DOK5,FHOD3,EFEMP1,NUMBL,CA2,SEMA4F,GATA2,FRAS1,LRP6,NOS3,FGFR4,DPYSL5,PAK1,UNC5C,CDH26,ATP5IF1,SLITRK2,SH2D2A,EFNA3,MAFB,STRADB,SLITRK5,OBSCN,PRDM1,SDK1,BAIAP2,ADGRB3,HEYL,CSF1,FAT1,EGFL7,SEMA3A,NKX2-8,SIX2,ID1,CELSR3,RBFOX2,ARHGAP22,COL18A1,RADIL,CBLN1,SEMA6A,SP8,CTNNA2,SETDB2,MYO3B,BCL6,ACVR2A,MET,NTNG1,SNAI2,SEMA6C,GLI1,INTU,FER,EVL,PTPN6,AMIGO1,JAM3,WARS,SMAD3,NRG3,PTK7,RBPMS2,ITGA2,HGF,CTNND2,HEY1,TENM1,TNIK,BMPR2,LRP4,APBB1,IGF2BP2,OVOL2,BMP6,NKX6-1,FOXP2,MAP1A,SCN1B,TFAP2A,SGK1,ACTA2,SH3PXD2B,SYK,DUSP1,MICAL2,MSX1,KDM5B,NR4A1,FOXN3,PRICKLE1,FERMT2,ZFPM2,PALLD,PEAK1,LEPR,MAP1B,DKK1,RERE,DOCK7,FAT4,EDA,FBN1,PRCP,CTSV,PAX9,MAP3K20,MMP16 |
| 6.822e-18 | -39.53 | CHICAS_RB1_TARGETS_CONFLUENT | MSigDB lists | CHICAS_RB1_TARGETS_CONFLUENT | 517 | 116 | 17377 | 1707 |
FAM171B,PRSS12,XYLT1,ASS1,FAM198B,ABAT,SPATS2L,QPRT,SIPA1L2,FKBP9,ASNS,KCNN2,ABI3BP,CNKSR3,STEAP3,SERPINH1,CPE,GARS,COL6A2,EVL,TUBA1A,SPOCD1,THSD4,TES,MSRB3,VIM,TMEM47,COTL1,ROR1,GPC6,NT5DC2,WARS,SMAD3,SLC7A1,CAMK2N1,GSN,AK1,GPRC5B,ITGBL1,GBP1,EIF4EBP1,RGS10,B3GALT2,HPGD,SEMA3C,OXTR,NRP1,TPM1,TNFSF4,NR3C2,PSPH,FRMD5,LPP,FARP1,IL32,IGFBP6,FN1,STXBP6,ITGA6,JDP2,BLVRB,DHCR24,PRSS35,CBS,SCD,GAS6,PHGDH,TNFRSF19,DOK5,FHOD3,MTUS1,MECOM,CHN1,RGS17,MAP1A,FRY,BACE2,OPN3,ACTA2,TOX,LOXL4,PCK2,ERRFI1,MOXD1,RRAS2,ZFP36L2,CAND2,SNX7,PARP9,PAK1,PDLIM7,MN1,IL17RD,SYNPO2,GSTM2,PXN,RAB3B,ARID5B,TCEA3,FHL2,SDC3,PRICKLE1,C1R,PALLD,EXOG,MAP1B,HEG1,ICA1,FBN1,MATN2,SLC7A5,SH3BP4,INHBE,UACA,BMP4,ATP2B4 |
| 6.882e-18 | -39.52 | NUYTTEN_EZH2_TARGETS_UP | MSigDB lists | NUYTTEN_EZH2_TARGETS_UP | 968 | 180 | 17377 | 1707 |
CCDC126,FLVCR2,ADAMTS6,SLC2A13,KIAA1217,DNER,RBM11,SNX9,NCS1,PCDH7,CCNJ,TYMP,PMAIP1,SLC16A2,MARVELD2,HRK,SP140,CTTN,THSD1,ENO1,SLIT2,LAMP3,GCNT2,MEIS2,PNRC1,KLHL4,CAP2,FAM84A,NFE2L1,SLC25A28,ROR1,TMEM47,CA13,AHRR,GPRC5B,MAP2,PLK2,ENTPD7,P4HA2,NCOA7,AHNAK2,BBC3,SERPINI1,DLX2,OXTR,NRP1,TPM1,FRMD5,UST,RUNX2,FN1,ZNF395,LGALS3,SEC24D,SETBP1,SLC1A3,CHSY1,HERC6,GRPEL2,DDIT4,EFEMP1,GALNT1,ABCA5,BACE2,FLRT3,BNIP3,FBXL2,MOXD1,TSPAN9,VGLL4,CKAP4,QSOX1,BDNF,RHOQ,ARID5B,C1R,SHISA2,ARRDC4,CLN5,FAM162A,STEAP1,HERPUD1,BAIAP2,DAGLA,PLAGL1,FCHO2,CSF1,MATN2,HK2,TMEM117,SEMA3A,SLFN5,SMYD3,PLA2G4A,ABHD13,RGS20,COBLL1,SPATS2L,DENND3,TNKS1BP1,DDX60L,TBC1D19,TLR3,KMO,STARD4,GULP1,MARCKS,WWC2,RAB27B,SP140L,IGFBP3,CTH,PHLDB2,PDK1,NECAB1,PFKFB2,SHANK2,C3orf52,ATF3,SYNJ2BP,ATP1B1,FBXO36,WARS,DCBLD2,ISG20,ARHGAP21,CXCL10,BACH2,ZNF704,PAM,P4HA1,GRB10,SUSD4,NR3C2,KCTD1,TNIK,MXI1,DYRK3,BMPR2,IL32,BACE1,FZD8,PRSS35,HERC5,GPR180,GAS6,CREB5,PHLDA2,MCU,HMGCS1,GPR155,GHR,STC2,SGK1,ERRFI1,RRAS2,ZFP36L2,PARP9,B4GALT6,PFKFB4,VEGFC,PRRG1,FERMT2,UCHL3,MAP1B,HOMER3,MKX,GPR37,CEBPB,GALNT3,MYADM,PLOD2,RND3,CLDN12,KIAA0513,GEM,KIF1B,PKIA,DDIT3,STOM |
| 8.305e-18 | -39.33 | developmental process | biological process | GO:0032502 | 5563 | 692 | 17256 | 1658 |
DOC2A,ARHGAP26,THOC5,PDE1B,RECK,MCOLN3,NPM1,CEBPA,CTBP2,STAT5B,CHAC1,BCAN,KIAA1217,EYA4,SKI,BAG3,TGFBR3,RAP2A,RAB26,PPP2R2B,TSHR,CPE,POU3F3,NKX2-1,MEIS2,SMAD9,DCC,CAP2,WLS,LRRK2,NFIA,HACD1,FEZ1,FGF17,ENPP1,WIPF3,ATP7B,BDH2,ADRB1,TMOD2,INPP5F,TPM1,TMEFF2,VASH2,MEF2C,SCN5A,GNG12,STOX2,ITGA6,TJP1,BBS9,FOXG1,HPCAL4,CHN1,SYCP2,FRY,FLRT3,ZIC5,TOX,LOXL4,NCAM1,STXBP1,GFRA1,CHRM3,LRP12,ZNF385A,HMGCR,BDNF,ENAM,SPATA6,ARID5B,FASN,FHL2,HIP1,CALCRL,SMARCD3,RYR2,SHISA2,SNAP25,TAF4B,MBNL2,CLN5,TEX15,SH3GL2,CDH17,INHBE,SELENOM,CLMN,HOXD13,SPRED3,CDH2,SHTN1,CSRP2,TFCP2L1,ZNF516,DNM3,PKP2,ADD2,COLEC10,NRXN1,TXNRD3,EPB41L3,TLR3,GPRIN1,DACT1,COL25A1,RTKN2,SYNGR3,MYT1,DNAH5,ZNF365,SNX10,PERP,FZD1,SSH3,MYLK3,ADM2,FZD4,NKX3-2,ADCY1,WNT11,RAB38,DSP,ASPH,FGFR1,GJC1,IRS2,CXCL10,APELA,WFS1,LAMB1,WWTR1,PAM,DBP,HOXB9,SERINC5,FARP1,C1QTNF3,EDA2R,ROBO2,FZD8,PLAG1,BIK,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,COL27A1,NEO1,HMGCS1,LRRN1,BHLHA15,MORN2,NPTXR,ZFP36L2,FES,MN1,VEGFC,PDLIM7,B9D1,LZTS3,RAPGEF2,AK4,RACK1,HEG1,PTPRC,ID3,PCDHB7,AKT3,GNAO1,XBP1,BMP4,JHY,SHOX2,FOXA1,CRISPLD1,BTRC,ATP2B4,PHC1,TPT1,TLL2,FGF13,LILRB1,ASS1,HDGFL3,NDRG2,NRN1,PLS3,RND2,KCNAB1,EOMES,MARVELD2,ITGB3,MPPED2,TBC1D32,COL19A1,LIN7A,ETV1,NEB,RAPGEF5,DBN1,ITGB7,GCNT2,ATF4,MARK1,COL4A3,ANK2,NFE2L1,CR2,PLEKHA1,BATF,PLEKHB1,TSKU,DYRK1B,INHBC,TCF7L1,INSIG1,MAP2,GNB4,TNFRSF1A,AHNAK2,DLX2,NEUROG2,MLLT3,CHMP4C,TYRO3,RUNX2,LGALS3,ZIC2,PGAP1,IL18R1,DOK5,FHOD3,EFEMP1,NUMBL,SEMA4F,IGF1R,GATA2,BCHE,FRAS1,SMTN,LRP6,ADCY6,BNIP3,MED7,SLCO4C1,PAK1,DPYSL5,FGFR4,UNC5C,GPSM1,EFNA3,SLITRK5,MAFB,STRADB,OBSCN,SDK1,BAIAP2,NEGR1,MAPKAPK2,MFSD2A,HEYL,CSF1,SEMA3A,TESC,SIX2,SFN,MME,PRKN,ID1,RBFOX2,NTRK3,RADIL,PCLO,SEMA6A,CBLN1,PPP1R9A,CTNNA2,RIDA,TACC2,LHX6,MYO3B,BCL6,MYH15,SCN2A,ZNF488,SNAI2,IGFBP3,GLI1,INTU,EVL,CSN2,TMEM65,PRDM13,FGF12,ACO1,VIM,RARRES2,FRK,JAM3,SMAD3,NRG3,PTK7,ITGA2,PTPRS,HGF,CTNND2,HEY1,CNTN1,TENM1,COL9A3,PCDH18,DYRK3,BMPR2,NLRP14,APBB1,MCTP2,GABRG2,PRDM8,PPP2R3A,ARHGAP44,FOXP2,MAP1A,FUT9,TFAP2A,SGK1,SH3PXD2B,PCK2,SYK,SLC45A3,ATP2B1,PCSK6,DUSP1,MICAL2,FOXN3,CRIP2,LITAF,PRICKLE1,FERMT2,PALLD,FNDC3A,ILDR2,MGMT,DKK1,MKX,EBF1,DOCK7,FAT4,FBN1,DLG2,PAX9,MYRF,ACVR1,LGR4,LDLR,GATA3,ENAH,ADAMTS6,PRKCA,RAC3,AARS,DACH2,NCS1,STK24,TRPS1,TYMP,CHRDL1,GSTM3,RCAN3,PACSIN1,KLHL3,SLC9C1,ACVR1C,MEF2B,EFHC1,AGO4,ACVR2B,SAV1,ARHGEF26,SPATA9,SFXN1,HLF,NCKAP1L,CCBE1,PLK2,BMP1,SEMA3C,SERPINI1,SPRY4,NRP1,SPART,UNC5B,TANC2,EFNB2,SEMA6B,LRFN5,INPPL1,MRC2,CELSR1,ZHX3,PTPRD,GABRB2,MLF1,SCN8A,DHCR24,SLC25A27,OPHN1,GTF2IRD1,SLC1A3,TNFRSF10C,HERC6,APBA1,TNFRSF19,CHD5,GAS1,MYORG,MECOM,ABLIM1,NAV1,CNTN4,SLC7A11,PDZD7,MYC,PRELID1,SREBF1,PRKG1,GRIP1,TSPAN12,COL9A2,GPR161,RIMS2,IGSF3,PTCH2,EPB41L5,DISC1,COL4A4,DCHS1,VLDLR,NSD2,PLCB1,DAGLA,MMP15,CECR2,WDR19,MATN2,DYNC2LI1,SFMBT1,DHCR7,SLFN5,SMYD3,EPHA3,NBL1,AMOTL1,ST14,GPR65,PLXNA2,OTX1,CHUK,DDR1,CCDC120,SPEG,ASNS,ALDOC,DAB2IP,PDE4D,SERPINH1,GATM,GAB2,SOX21,SHANK2,PREX1,NLGN4X,SATB2,ATF3,PRKCQ,CBY1,ATOH1,PYGO1,SNCA,IKZF3,POPDC3,BEX3,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,ATG5,MAPK10,CTTNBP2,COBL,MID1,STON2,WASF3,MYO1D,KIF5C,SELENOP,GDPD5,PHLDA2,NEDD4,ADGRB2,HOPX,KDM7A,LRRC55,IRX5,SOAT2,MGAT1,AFF2,DYNC2H1,FIG4,ERRFI1,YBX3,SMAD6,GFI1,SPRY2,VAV3,SLC40A1,ARHGEF28,TMEM126A,ZDHHC15,HOXA1,ZIC1,GPLD1,CEBPB,FGR,TERT,PCGF2,SVIL,TUFT1,GRIN2D,MYOM2,LRRK1,TNFRSF17,DDIT3,EXPH5,UGT8,KIF5A,UGDH,ACTL8,ABAT,RBM11,DNER,KREMEN1,GSDME,EPCAM,LRRC6,GRHL1,DLX6,POF1B,CTTN,EPHB6,SLIT2,IL1RAP,PRKACB,PDGFRB,RASGRP1,CYP1B1,ATL1,TNK2,GPM6A,CEMIP2,JPH1,YAP1,ROR1,EML1,GSN,GPRC5B,HPSE,NCAM2,OXTR,PPARGC1A,MAGI2,APBA2,PCSK5,UST,BCL11B,FN1,SEC24D,BVES,FBXO4,LAMC3,CHSY1,SPINK5,PHGDH,SATB1,ADGRG6,DDIT4,PCDHB14,EEF2,ZNF354A,CA2,EBF4,BARX1,NOS3,ATP5IF1,PCDH10,CDH26,RAX,SLITRK2,MSTN,SH2D2A,PRDM1,RIPOR2,PLAGL1,ADGRB3,FAT1,RAI14,HK2,EGFL7,NKX2-8,CREB3L2,CXCR5,ZSWIM5,CELSR3,IL15,PLEKHA5,ARHGAP22,COL18A1,HECW2,TDRKH,CANX,DOCK2,SP8,KCTD15,UNC13B,SETDB2,KAZN,ZNF521,ACVR2A,POU2F2,MET,TMEM120B,HSPA2,NTNG1,SEMA6C,PRAME,FER,PTPRU,PTPN6,AMIGO1,CD40,TTLL7,BATF3,WARS,BCL11A,ARMC4,MSC,RBPMS2,SOHLH2,DISP1,TNIK,CMTM8,LRP4,IGF2BP2,OVOL2,BMP6,NKX6-1,SCN1B,GTSF1,DSG2,PRKCD,STC2,KIAA0319,ACTA2,TRIM3,MTURN,RRAS2,TNFRSF11A,MSX1,USP2,KDM5B,CRIM1,NR4A1,SYBU,MEI1,ZFPM2,PEAK1,LEPR,RERE,MAP1B,DPY19L2,MYADM,EDA,PRCP,CTSV,SLC7A5,MAP3K20,NPHP1,MMP16,SNPH |
| 9.196e-18 | -39.23 | nervous system development | biological process | GO:0007399 | 2259 | 335 | 17256 | 1658 |
DOC2A,ARHGAP26,LDLR,MCOLN3,GATA3,ENAH,CHAC1,PRKCA,BCAN,AARS,RAC3,NCS1,STK24,SKI,BAG3,RAP2A,CHRDL1,GSTM3,PACSIN1,TSHR,POU3F3,NKX2-1,SMAD9,DCC,WLS,LRRK2,NFIA,FEZ1,EFHC1,FGF17,NCKAP1L,PLK2,SEMA3C,SERPINI1,TMOD2,INPP5F,UNC5B,NRP1,SPART,MEF2C,EFNB2,LRFN5,SEMA6B,SCN5A,GNG12,CELSR1,PTPRD,GABRB2,SCN8A,OPHN1,SLC1A3,APBA1,FOXG1,CHD5,HPCAL4,CHN1,NAV1,CNTN4,SLC7A11,FRY,PDZD7,FLRT3,ZIC5,PRKG1,GRIP1,NCAM1,STXBP1,GFRA1,RIMS2,LRP12,CHRM3,BDNF,DISC1,VLDLR,DCHS1,SMARCD3,SNAP25,PLCB1,CLN5,DAGLA,SH3GL2,CECR2,MATN2,WDR19,CLMN,CDH2,SHTN1,EPHA3,NBL1,DNM3,ST14,PLXNA2,OTX1,NRXN1,DDR1,EPB41L3,GPRIN1,DACT1,COL25A1,DAB2IP,SYNGR3,MYT1,ZNF365,GAB2,FZD1,SSH3,FZD4,SHANK2,PREX1,ADCY1,NLGN4X,SATB2,WNT11,PRKCQ,ATOH1,FGFR1,IRS2,LAMB1,PAM,GRB10,BMPR1A,MAPK10,CTTNBP2,COBL,WASF3,SERINC5,MYO1D,FARP1,ROBO2,FZD8,PLAG1,KIF5C,GAS6,P2RY1,EPHB1,SELENOP,GDPD5,ADGRB2,NEDD4,NEO1,KDM7A,LRRC55,IRX5,HMGCS1,LRRN1,AFF2,DYNC2H1,FIG4,NPTXR,GFI1,FES,VEGFC,PDLIM7,LZTS3,RAPGEF2,TMEM126A,AK4,HOXA1,ZIC1,CEBPB,ID3,PCDHB7,TERT,AKT3,GNAO1,XBP1,GRIN2D,BMP4,JHY,SHOX2,FOXA1,ATP2B4,UGT8,FGF13,KIF5A,HDGFL3,NDRG2,NRN1,ABAT,DNER,GSDME,RND2,EOMES,KCNAB1,DLX6,TBC1D32,MPPED2,CTTN,ETV1,IL1RAP,SLIT2,RAPGEF5,PRKACB,DBN1,ATL1,GPM6A,MARK1,ATF4,ANK2,YAP1,ROR1,EML1,TSKU,TCF7L1,GSN,GPRC5B,NCAM2,MAP2,GNB4,AHNAK2,DLX2,OXTR,PPARGC1A,APBA2,NEUROG2,MAGI2,UST,BCL11B,TYRO3,RUNX2,FN1,LAMC3,ZIC2,PHGDH,SPINK5,ADGRG6,PGAP1,DOK5,DDIT4,PCDHB14,NUMBL,SEMA4F,EEF2,BCHE,GATA2,ADCY6,LRP6,BNIP3,BARX1,FGFR4,DPYSL5,PAK1,RAX,UNC5C,PCDH10,SLITRK2,EFNA3,GPSM1,MAFB,SLITRK5,PRDM1,SDK1,BAIAP2,NEGR1,ADGRB3,MFSD2A,HEYL,CSF1,SEMA3A,NKX2-8,PRKN,ZSWIM5,ID1,CELSR3,RBFOX2,HECW2,NTRK3,PCLO,CBLN1,PPP1R9A,SEMA6A,CTNNA2,RIDA,UNC13B,TACC2,LHX6,BCL6,ZNF521,SCN2A,ZNF488,NTNG1,SEMA6C,GLI1,INTU,EVL,PRDM13,FGF12,VIM,AMIGO1,TTLL7,JAM3,BCL11A,ARMC4,NRG3,PTK7,PTPRS,HGF,CTNND2,CNTN1,TENM1,PCDH18,TNIK,BMPR2,LRP4,APBB1,CMTM8,PRDM8,OVOL2,BMP6,ARHGAP44,NKX6-1,FOXP2,MAP1A,FUT9,SCN1B,KIAA0319,TFAP2A,TRIM3,SGK1,SLC45A3,ATP2B1,MSX1,CRIM1,SYBU,PRICKLE1,MAP1B,DKK1,RERE,DOCK7,FAT4,CTSV,SLC7A5,DLG2,MYRF,SNPH |
| 9.610e-18 | -39.18 | prostate | COSMIC cancer mutations | prostate | 14295 | 1517 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,GRK6,TLR3,ALDH1L1,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,PGBD5,DBN1,MARK1,KCNIP3,ATF4,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,NDUFA4L2,DPYSL5,BTNL9,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,NEGR1,TBC1D2,GRIK4,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,HEY1,TENM1,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,DKK1,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,CD40,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,PRKCD,STC2,ACTA2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,LPP,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,FAM131C,GALNT6,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,COL27A1,NEO1,GAS2L3,MYO6,NPTXR,FES,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,PLPPR2,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,DOCK6,DCBLD1,BTRC,FOXA1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,MAPKAPK2,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,THSD4,FGF12,GSTO1,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,SLC22A15,PAX9,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,ANO10,WASF3,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,NOS3,GPR176,IL17RD,RAX,SH2D2A,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.206e-17 | -38.96 | BENPORATH_ES_WITH_H3K27ME3 | MSigDB lists | BENPORATH_ES_WITH_H3K27ME3 | 1048 | 190 | 17377 | 1707 |
CACNG3,PDE1B,SIDT1,DUSP8,PRSS12,SYT12,MCOLN3,GATA3,NRN1,ANKRD18A,BCAN,DNER,CACNB4,SLCO3A1,DACH2,EYA4,PPM1E,RPS6KA2,EOMES,KCNAB1,ZFYVE28,CHRDL1,KCNS3,CNNM2,HRK,TMEM132E,SLIT2,NKX2-1,EIF4E3,DCC,GJB2,TGFA,FAM84A,NFIA,ELMOD1,FEZ1,CR2,KCND3,GPR150,TRIM9,GSN,HPSE,ADRB1,TMOD2,DLX2,UNC5B,TMEFF2,NEUROG2,MLLT3,SPOCK3,CRYL1,HS6ST3,KCNV1,LRFN5,SV2B,RUNX2,LGALS3,GABRB2,CYP2J2,STXBP6,RIMKLA,SLC25A27,FAM81A,APBA1,FOXG1,DYNC1I1,CHD5,HPCAL4,MECOM,IL17D,SEMA4F,SLC30A4,NOVA2,GATA2,PDE10A,SAMD11,PRKG1,NCAM1,MAST4,BARX1,COL9A2,NDUFA4L2,DPYSL5,ANKRD20A2,RAX,UNC5C,KCNQ3,SLC27A2,PARD3B,ARID5B,RAPGEF4,TCEA3,EFNA3,MAFB,PDE8A,NEGR1,C11orf45,SH3GL2,CSF1,HEYL,PTPRN2,NXPH4,HOXD13,NKX2-8,SIX2,EPHA3,NBL1,XYLT1,PLXNA2,RGS20,OTX1,MAPK4,NRXN1,CBLN1,CYP26A1,SCIN,COL25A1,LHX6,REEP1,ANKRD18B,SNAI2,FZD1,IGFBP3,ANKRD20A3,PTPRU,NKX3-2,PRDM13,WNT11,ATF3,SATB2,ATOH1,RARRES2,TTLL7,BATF3,HTR7,CAMK2N1,MSC,IKZF3,PRKCB,LAMB1,CCNA1,RGS10,GRB10,HS3ST3B1,SUSD4,CTNND2,HEY1,KLHL13,BLVRB,CLSTN2,NKAIN2,COL4A5,NOTUM,EPHB1,KCNC4,BMP6,COL27A1,NKX6-1,KCNJ4,CHN2,FUT9,STC2,GHR,ULBP1,SLC40A1,VAV3,MSX1,CACNA1E,ELOVL3,GRID1,AGAP2,SNTB1,SKAP1,LRAT,ILDR2,HOXA1,ZIC1,DKK1,MKX,ADAMTS17,DPY19L2,EBF1,DDAH1,FBN1,GNAO1,SLCO5A1,GRIN2D,PAX9,SHOX2,ATP1A3 |
| 1.305e-17 | -38.88 | large_cell | COSMIC cancer mutations | large_cell | 15281 | 1593 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH,STOM |
| 1.314e-17 | -38.87 | clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_renal_cell_carcinoma | 14301 | 1517 | 17385 | 1698 |
ARHGAP26,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,DCC,KLHL23,EXOC6B,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,TLR3,MAGEA3,ALDH1L1,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,WDR17,CKAP2,FZD8,ESRP1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,USP30,SLC35F1,FOXP2,TTC1,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,DKK1,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CTTN,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,LIMCH1,RNF148,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,CD40,ZNF569,BCL11A,ARMC4,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,LPP,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,RSL24D1,BNIP1,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,THSD4,FGF12,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,ATRNL1,BEND4,SP140,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,MYOM2,OCLN,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,RPS11,EBF4,FAM107B,NCEH1,NOS3,ANKRD20A2,IL17RD,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.314e-17 | -38.87 | kidney-carcinoma-clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_renal_cell_carcinoma | 14301 | 1517 | 17385 | 1698 |
ARHGAP26,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,DCC,KLHL23,EXOC6B,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,TLR3,MAGEA3,ALDH1L1,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,WDR17,CKAP2,FZD8,ESRP1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,USP30,SLC35F1,FOXP2,TTC1,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,DKK1,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CTTN,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,LIMCH1,RNF148,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,CD40,ZNF569,BCL11A,ARMC4,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,LPP,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,RSL24D1,BNIP1,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,THSD4,FGF12,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,ATRNL1,BEND4,SP140,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,MYOM2,OCLN,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,RPS11,EBF4,FAM107B,NCEH1,NOS3,ANKRD20A2,IL17RD,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.516e-17 | -38.73 | CAGGTG_V$E12_Q6 | MSigDB lists | CAGGTG_V$E12_Q6 | 2317 | 347 | 17377 | 1707 |
DOC2A,ARHGAP26,LANCL3,TCP11L2,SIDT1,PRSS12,GATA3,CADM2,CHAC1,DOCK3,EYA4,HECTD2,NOS1AP,SLC9A7,EPDR1,PCDH7,TRPS1,TYMP,FBXO32,IKZF5,RAB26,SERINC2,NDUFB8,TMED9,PPP2R2B,POU3F3,TBC1D8,NKX2-1,RWDD2A,MEIS2,ERGIC1,KLHL3,NR6A1,DSTN,GJB2,TNS1,ACVR2B,KCND3,F12,SH3RF1,ATP7B,RASGRF2,ALDOA,ADRB1,SERPINI1,SPRY4,UNC5B,TMEFF2,DNHD1,MEF2C,LRFN5,SCN5A,ITGA6,OPHN1,TJP1,APBA1,CHD5,HPCAL4,GRPEL2,MTUS1,CNTN4,SLC7A11,PIK3AP1,NOVA2,CACNB2,MYC,PRELID1,SRGAP1,NCAM1,STXBP1,AGL,GFRA1,RIMS2,IGSF3,RNF152,EPB41L5,BDNF,KCNQ3,COL4A4,RAPGEF4,PACSIN3,AIG1,SNAP25,PLCB1,FAM162A,DAGLA,MMP15,RPL28,SH3GL2,PMEPA1,SQLE,CDH2,AMPD1,NBL1,RASAL2,RHOD,OTX1,PLXNA2,IL13RA1,NRXN1,DDR1,ZFYVE9,CDS1,ZNF827,SPEG,NBEA,RTKN2,SYNGR3,FAM155B,SNX10,GATM,KCNB2,GAB2,SSH3,GAPDH,PFKFB2,FZD4,KCNH5,SHANK2,PRKCQ,WNT11,ATP1B1,DSP,TTC28,MAGI3,SNCA,SLC39A14,PDLIM3,HPGD,DBP,MAPK10,NR3C2,MID1,COBL,CCDC148,ANKRD13B,IGFBP6,PLAG1,BACE1,EPS8,SLC12A6,PKN1,RGS7,ATXN7L1,RGS17,HMGCS1,LRRN1,MGAT1,PCBP4,FIG4,ERRFI1,SEPT3,SPRY2,MED12L,FES,B4GALT6,ARAP2,CACNA1E,ELOVL3,ZDHHC15,UCHL3,SKAP1,HOXA1,ID3,FGR,PLOD2,GNAO1,TUFT1,BMP4,FOXA1,OCLN,SLC43A1,TLL2,EXPH5,PHACTR3,FGF13,UGDH,ASS1,MGAT5B,ITPR2,ABHD4,IKZF2,SLCO3A1,HMCN1,FKBP11,CCNJ,EPCAM,RTN1,LGI2,KCNN2,MPPED2,COL19A1,CNNM2,EPHB6,ETV1,NEB,SLIT2,RAPGEF5,CYP1B1,MARK1,COL4A3,ANK2,ATOX1,ROR1,SERGEF,PLEKHB1,EML1,GPRC5B,NCAM2,ERN1,DLX2,PPARGC1A,MLLT3,FRMD5,RRAGD,HS6ST3,UST,BCL11B,TYRO3,SV2B,ZNF395,CHCHD7,RHOBTB1,UBASH3B,RIMKLA,ZIC2,SORBS3,FAM81A,EFEMP1,NUMBL,IGF1R,GATA2,SMTN,LRP6,SLCO4C1,PTPRCAP,NIPAL2,VGLL4,DPYSL5,PAK1,MID2,RHOQ,SLC27A2,PARD3B,MGAT4B,EDEM3,DUSP9,WWC1,PDE8A,PRDM1,SDK1,KHDRBS2,NEGR1,KIAA0355,MFSD2A,HEYL,NXPH4,SEMA3A,RNF122,FNBP1L,SFN,SIX2,CXCR5,EML5,SORBS1,ID1,XYLT1,COL18A1,NTRK3,TDRKH,CANX,DENND3,PRR7,CBLN1,SEMA6A,CYP26A1,COL22A1,KCTD15,SLC22A17,UNC13B,TACC2,KAZN,BCL6,ZNF521,MAP7,ACVR2A,TMEM56,SEMA6C,GLI1,GCA,TMEM65,FGF12,SYNJ2BP,DOCK5,BCL11A,SMAD3,MSC,PTPRJ,EIF4EBP1,ITGA2,HGF,COL9A3,KLHL13,CMTM8,GABRG2,SELL,FAM117B,IGF2BP2,OVOL2,SEL1L3,FAM174B,BMP6,ARHGAP44,KCNJ4,TECPR1,MAP1A,FUT9,DSG2,RASD2,STC2,TSC22D1,TFAP2A,TSPAN13,MICAL2,USP2,CRIM1,NR4A1,ESRRG,CYTH3,AGAP2,ARHGAP32,FNDC3A,PALLD,GALNT14,LRAT,ILDR2,GPR37,ADAMTS17,EBF1,DDAH1,UACA,DLG2,SH3BGRL2,PAX9,MMP16,PKIA,C2orf27A |
| 3.188e-17 | -37.98 | anatomical structure development | biological process | GO:0048856 | 5202 | 652 | 17256 | 1658 |
DOC2A,ARHGAP26,THOC5,PDE1B,RECK,MCOLN3,CEBPA,STAT5B,CHAC1,BCAN,KIAA1217,EYA4,SKI,BAG3,TGFBR3,RAP2A,RAB26,TSHR,CPE,POU3F3,NKX2-1,MEIS2,SMAD9,DCC,CAP2,WLS,LRRK2,NFIA,HACD1,FEZ1,FGF17,ENPP1,WIPF3,ATP7B,BDH2,TMOD2,INPP5F,TPM1,TMEFF2,VASH2,MEF2C,SCN5A,GNG12,STOX2,ITGA6,TJP1,FOXG1,HPCAL4,CHN1,SYCP2,FRY,FLRT3,ZIC5,TOX,LOXL4,NCAM1,STXBP1,GFRA1,CHRM3,LRP12,ZNF385A,HMGCR,BDNF,ENAM,SPATA6,ARID5B,FASN,FHL2,CALCRL,SMARCD3,RYR2,SHISA2,SNAP25,TAF4B,CLN5,SH3GL2,CDH17,INHBE,SELENOM,CLMN,HOXD13,SPRED3,CDH2,SHTN1,CSRP2,TFCP2L1,ZNF516,DNM3,PKP2,ADD2,COLEC10,NRXN1,TXNRD3,EPB41L3,TLR3,GPRIN1,DACT1,COL25A1,RTKN2,SYNGR3,MYT1,DNAH5,ZNF365,SNX10,PERP,FZD1,SSH3,MYLK3,ADM2,FZD4,NKX3-2,ADCY1,WNT11,DSP,ASPH,FGFR1,GJC1,IRS2,CXCL10,APELA,WFS1,LAMB1,WWTR1,PAM,DBP,HOXB9,SERINC5,FARP1,EDA2R,ROBO2,FZD8,PLAG1,BIK,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,COL27A1,NEO1,HMGCS1,LRRN1,BHLHA15,NPTXR,ZFP36L2,FES,MN1,VEGFC,PDLIM7,B9D1,LZTS3,RAPGEF2,AK4,RACK1,HEG1,PTPRC,ID3,PCDHB7,AKT3,GNAO1,XBP1,BMP4,JHY,SHOX2,FOXA1,CRISPLD1,BTRC,ATP2B4,PHC1,TLL2,FGF13,LILRB1,ASS1,HDGFL3,NDRG2,NRN1,PLS3,RND2,KCNAB1,EOMES,MARVELD2,ITGB3,MPPED2,TBC1D32,COL19A1,LIN7A,ETV1,NEB,RAPGEF5,DBN1,ITGB7,GCNT2,ATF4,MARK1,COL4A3,ANK2,NFE2L1,CR2,PLEKHA1,BATF,PLEKHB1,TSKU,DYRK1B,INHBC,TCF7L1,INSIG1,MAP2,GNB4,TNFRSF1A,AHNAK2,DLX2,NEUROG2,MLLT3,CHMP4C,TYRO3,RUNX2,LGALS3,ZIC2,PGAP1,IL18R1,DOK5,FHOD3,EFEMP1,NUMBL,IGF1R,SEMA4F,GATA2,BCHE,FRAS1,SMTN,LRP6,ADCY6,BNIP3,SLCO4C1,PAK1,DPYSL5,FGFR4,UNC5C,GPSM1,EFNA3,SLITRK5,MAFB,STRADB,OBSCN,SDK1,BAIAP2,NEGR1,MAPKAPK2,MFSD2A,HEYL,CSF1,SEMA3A,SIX2,SFN,MME,PRKN,ID1,RBFOX2,NTRK3,RADIL,PCLO,SEMA6A,CBLN1,PPP1R9A,CTNNA2,RIDA,TACC2,LHX6,MYO3B,BCL6,MYH15,SCN2A,ZNF488,SNAI2,GLI1,INTU,EVL,CSN2,TMEM65,PRDM13,FGF12,ACO1,VIM,RARRES2,JAM3,SMAD3,NRG3,PTK7,ITGA2,PTPRS,HGF,CTNND2,HEY1,CNTN1,TENM1,COL9A3,PCDH18,DYRK3,BMPR2,NLRP14,APBB1,MCTP2,GABRG2,PRDM8,ARHGAP44,PPP2R3A,FOXP2,MAP1A,FUT9,TFAP2A,SGK1,SH3PXD2B,PCK2,SYK,SLC45A3,ATP2B1,PCSK6,DUSP1,MICAL2,FOXN3,CRIP2,FERMT2,PRICKLE1,FNDC3A,PALLD,ILDR2,MGMT,MKX,DKK1,EBF1,DOCK7,FAT4,FBN1,DLG2,PAX9,MYRF,ACVR1,LGR4,LDLR,GATA3,ENAH,ADAMTS6,PRKCA,RAC3,AARS,DACH2,STK24,NCS1,TRPS1,TYMP,CHRDL1,GSTM3,RCAN3,PACSIN1,KLHL3,SLC9C1,MEF2B,EFHC1,AGO4,ACVR2B,SAV1,ARHGEF26,SPATA9,SFXN1,HLF,NCKAP1L,CCBE1,PLK2,BMP1,SEMA3C,SERPINI1,SPRY4,NRP1,SPART,UNC5B,TANC2,EFNB2,SEMA6B,LRFN5,INPPL1,CELSR1,PTPRD,GABRB2,MLF1,SCN8A,DHCR24,SLC25A27,OPHN1,GTF2IRD1,SLC1A3,TNFRSF10C,HERC6,APBA1,TNFRSF19,CHD5,MYORG,MECOM,ABLIM1,NAV1,CNTN4,SLC7A11,PDZD7,MYC,PRELID1,SREBF1,PRKG1,GRIP1,TSPAN12,COL9A2,GPR161,RIMS2,IGSF3,PTCH2,EPB41L5,DISC1,COL4A4,DCHS1,VLDLR,NSD2,PLCB1,DAGLA,MMP15,CECR2,WDR19,MATN2,DYNC2LI1,DHCR7,SMYD3,EPHA3,NBL1,AMOTL1,ST14,GPR65,PLXNA2,OTX1,CHUK,DDR1,CCDC120,SPEG,ASNS,ALDOC,DAB2IP,PDE4D,SERPINH1,GATM,GAB2,SOX21,SHANK2,PREX1,NLGN4X,SATB2,ATF3,PRKCQ,CBY1,ATOH1,PYGO1,IKZF3,POPDC3,BEX3,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,ATG5,MAPK10,CTTNBP2,COBL,MID1,STON2,WASF3,MYO1D,KIF5C,SELENOP,GDPD5,PHLDA2,NEDD4,ADGRB2,HOPX,KDM7A,LRRC55,IRX5,MGAT1,AFF2,DYNC2H1,FIG4,ERRFI1,YBX3,SMAD6,GFI1,SPRY2,VAV3,SLC40A1,TMEM126A,HOXA1,ZIC1,GPLD1,CEBPB,TERT,PCGF2,SVIL,TUFT1,GRIN2D,MYOM2,LRRK1,TNFRSF17,DDIT3,EXPH5,UGT8,KIF5A,UGDH,ACTL8,ABAT,DNER,RBM11,KREMEN1,GSDME,EPCAM,LRRC6,GRHL1,DLX6,POF1B,CTTN,EPHB6,SLIT2,IL1RAP,PRKACB,PDGFRB,CYP1B1,ATL1,GPM6A,CEMIP2,JPH1,YAP1,ROR1,EML1,GSN,GPRC5B,HPSE,NCAM2,OXTR,PPARGC1A,MAGI2,APBA2,PCSK5,UST,BCL11B,FN1,SEC24D,BVES,LAMC3,CHSY1,SPINK5,PHGDH,SATB1,ADGRG6,DDIT4,PCDHB14,EEF2,ZNF354A,CA2,EBF4,BARX1,NOS3,ATP5IF1,PCDH10,CDH26,RAX,SLITRK2,MSTN,SH2D2A,PRDM1,RIPOR2,ADGRB3,FAT1,HK2,EGFL7,NKX2-8,CREB3L2,CXCR5,ZSWIM5,CELSR3,IL15,PLEKHA5,ARHGAP22,COL18A1,HECW2,DOCK2,SP8,KCTD15,UNC13B,SETDB2,KAZN,ZNF521,ACVR2A,POU2F2,MET,HSPA2,NTNG1,SEMA6C,FER,PTPRU,PTPN6,AMIGO1,CD40,TTLL7,BATF3,WARS,BCL11A,ARMC4,MSC,RBPMS2,SOHLH2,DISP1,TNIK,CMTM8,LRP4,IGF2BP2,OVOL2,BMP6,NKX6-1,SCN1B,DSG2,STC2,KIAA0319,ACTA2,TRIM3,MTURN,TNFRSF11A,MSX1,USP2,KDM5B,CRIM1,NR4A1,SYBU,MEI1,ZFPM2,PEAK1,LEPR,RERE,MAP1B,DPY19L2,MYADM,EDA,PRCP,CTSV,SLC7A5,MAP3K20,NPHP1,MMP16,SNPH |
| 3.998e-17 | -37.76 | cell periphery | cellular component | GO:0071944 | 5361 | 661 | 18223 | 1724 |
DOC2A,TRIM16L,FLVCR2,GRIK2,PRSS12,CNTNAP3,RECK,MCOLN3,CADM2,SNX9,ABHD6,NOS1AP,PCDH7,BAG3,TGFBR3,RAP2A,RAB26,COG3,TSHR,CPE,DCC,WLS,CAP2,EXOC6B,DSTN,GJB2,TGFA,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,F12,SLC7A1,ENPP1,WIPF3,ATP7B,ADRB1,DIRAS1,TPM1,LPP,SCN5A,GNG12,ITGA6,TJP1,SLC36A4,GPSM2,BBS9,FRY,BACE2,CACNB2,FLRT3,LMAN2,CADPS2,FAM84B,NCAM1,JAM2,STXBP1,TSPAN9,GFRA1,LRP12,CHRM3,KCNQ3,MYO10,FASN,RYR2,HIP1,CALCRL,PLS1,SNAP25,OR11H4,ARRDC4,CPEB1,SH3GL2,CDH17,LAPTM4B,CDH2,TRPC3,BTC,DNM3,SCAMP1,C4A,MYO1B,RGS20,PKP2,ADD2,IL13RA1,GRK6,NRXN1,LCP2,SLC19A2,GPR15,EPB41L3,PLPP1,TLR3,GPRIN1,CHRNA5,COL25A1,CNKSR3,RTKN2,FAM155B,ARL4D,RAB27B,KIAA1549,PERP,SCN3A,DOCK8,KCNB2,FZD1,COL6A2,GAPDH,FZD4,KCNH5,ADCY1,RAB38,DSP,ASPH,FGFR1,MAGI3,GABARAPL1,GJC1,IRS2,ENTPD1,SLC39A14,CXCL10,ARHGAP21,GYPC,GPR160,PEMT,PAM,TNFSF15,LRRC27,C2orf88,SERINC5,FARP1,ANKRD13B,EDA2R,ROBO2,BACE1,FZD8,CD276,NKAIN2,PSD3,P2RY1,SLC12A6,PKN1,EPHB1,KCNC4,TSPAN17,NEO1,MCF2L,GHR,MYO6,NPTXR,FES,ULBP1,TRPM4,LZTS3,RAPGEF2,RASA3,GAREM1,ATP11A,RACK1,SNTB1,HEG1,PTPRC,TRIB3,PCDHB7,PLPPR2,GNAO1,SLCO5A1,ATP2B4,CACNG3,FGF13,TRIM16,SYT12,LILRB1,NRN1,ITPR2,SYT14,PLS3,RND2,CPNE2,TM9SF2,KCNAB1,KCNN2,TCAF2,HPS1,MARVELD2,ITGB3,LIN7A,TLN2,TLR4,ENO1,DBN1,ITGB7,CD55,KCNIP3,SLC3A2,ATF4,MARK1,ABCC4,ANK2,PLPP2,CR2,PLEKHA1,TSKU,KCNMB4,TNFRSF1A,AHNAK2,PIK3C2B,ADGRA3,TC2N,TYRO3,KCNV1,RGS16,LGALS3,STXBP5L,ITPRIP,MLC1,IL18R1,SPIRE1,IGF1R,SEMA4F,FRAS1,LRP6,ADCY6,SLCO4C1,PTPRCAP,CKAP4,PAK1,FGFR4,UNC5C,BTNL9,SLC27A2,HOMER2,EFNA3,GPSM1,SPATA13,SLITRK5,OBSCN,SDK1,GPR19,BAIAP2,NEGR1,KCNK15,GRIK4,MFSD2A,CSF1,SLC2A6,PLD1,TESC,MME,AKAP5,NTRK3,OR51B4,SLC7A2,SEZ6L2,PRR7,PCLO,PPP1R9A,SEMA6A,CBLN1,CTNNA2,SLC22A17,TACC2,ADGRL1,SCN2A,TMEM67,EVA1A,LRRC8B,TMEM65,CHRNA6,VIM,FRK,JAM3,C4BPB,SMAD3,NRG3,PTPRJ,GBP1,PTK7,KCNG1,ITGA2,PTPRS,SEPT5,CNTN1,TENM1,PCDH18,LPAR2,NECAB2,SLC6A9,BMPR2,GRB14,APBB1,BLVRB,GABRG2,SELL,RASD1,ARHGAP44,RASD2,KCNMB3,SGK1,TSPAN13,KLF9,SYK,SLC45A3,ATP2B1,PCSK6,DLGAP1,CRIP2,LITAF,FERMT2,PALLD,NPDC1,SMPDL3B,HOMER3,DKK1,CD37,FAT4,DLG2,SLC22A15,SLC1A5,FILIP1,CACNA2D1,CGN,ACVR1,LANCL3,LGR4,ATP8A1,LDLR,VAMP8,ENAH,PRKCA,RAC3,NCS1,SLC9A7,SLC16A2,SLC22A18,KCNS3,PACSIN1,GLDC,SLC9C1,ACVR1C,LRMP,ACVR2B,GPC6,GNAI1,GPR150,ENPP6,NCKAP1L,RASGRF2,SPRY4,SPART,UNC5B,NRP1,LZTS1,EFNB2,SEMA6B,MRC2,INPPL1,CELSR1,PTPRD,GABRB2,SCN8A,SLC1A3,TNFRSF10C,APBA1,TNFRSF19,GAS1,MTUS1,MCOLN2,RALGPS2,SLC7A11,CNTN4,PIK3AP1,PDZD7,MSMO1,SCARF2,PRKG1,OPN3,GRIP1,SLC16A9,TSPAN12,MPDZ,FAM155A,GPR161,RIMS2,IGSF3,EPB41L5,DISC1,SLC36A1,DCHS1,RAPGEF4,VLDLR,PACSIN3,TTYH2,RABAC1,MMP15,DAGLA,PLEKHH2,PMEPA1,MPP2,FRMPD3,EPHA3,AMOTL1,RASAL2,TCTN2,RNF144A,RHOD,ST14,GPR65,PLXNA2,MSR1,KCTD12,CHUK,TMEM170B,DDR1,TBC1D30,NBEA,DAB2IP,MARCKS,PDE4D,GAB2,VNN2,SHANK2,PANK1,PREX1,NLGN4X,PRKCQ,ATP1B1,ATP10D,PATJ,DCBLD2,SNCA,HTR7,IKZF3,POPDC3,PRKCB,ASIC1,MAP3K21,HPGD,GRB10,BMPR1A,HS3ST3B1,MAPK10,CTTNBP2,COBL,ANO10,MYO1D,PLSCR4,ANKRD13D,GLIPR1L1,ATP9A,EPS8,ARL2,GABRR2,RGS7,SLC35G2,ADGRB2,NEDD4,RGS17,LRRC55,RALGAPA2,PRKG2,SLC6A15,DYNC2H1,ERRFI1,SEPT3,SPRY2,SLC40A1,VAV3,PXN,ARHGEF28,PTPN13,MPP1,CACNA1E,GUCY1A2,SKAP1,FGR,OR2T33,TERT,CLDN12,MCC,SVIL,GRIN2D,TNFRSF17,OCLN,ATP1A3,SLC43A1,UGT8,ACSL1,SLC2A13,CACNB4,DNER,KREMEN1,SLCO3A1,HMCN1,GSDME,F3,EPCAM,CYP51A1,SLC10A7,TRPC1,CNNM2,SLC2A12,EPHB6,CTTN,OR2W3,PTPRE,MYRIP,IL1RAP,SLIT2,RASGRP1,PDGFRB,PRKACB,LAMP3,TNK2,GPM6A,SKAP2,CEMIP2,JPH1,TMEM47,ROR1,GRK3,GSN,TMEM150B,GPRC5B,ITGBL1,NCAM2,OXTR,TNFSF4,MAGI2,APBA2,SLC9B1,GPR63,SV2B,FN1,BVES,SCART1,RHOBTB1,STXBP6,CD7,SPINK5,ADGRG6,PCDHB14,EEF2,CA2,VSIR,NOS3,PCDH10,CDH26,IL17RD,GPR176,RHOQ,PODXL2,SLITRK2,PARD3B,WWC1,SDC3,CATSPERE,STEAP1,RIPOR2,ADGRB3,FCHO2,NCR3LG1,FAT1,RAB31,RAI14,PTPRN2,TMEM117,DISP2,FNBP1L,OSBPL6,CXCR5,SORBS1,IL15,CELSR3,SCIN,CD53,UNC13B,PPFIBP1,KAZN,MAP7,ACVR2A,STEAP3,FHIT,PROS1,MET,NTNG1,HSPA2,SEMA6C,ALG10B,SUSD3,DPP10,GCA,ANTXR2,PRAME,FER,PHLDB2,PTPRU,SLC39A8,TES,PTPN6,AMIGO1,CD40,DOCK5,CAMK2N1,TMPRSS9,RGS10,DISP1,LIFR,MAST1,OR51B5,TNIK,ENO2,TSPAN15,LRP4,TNFSF13B,CLSTN2,FSD1,KCNJ4,SCN1B,PRKCD,EHD3,DSG2,KIAA0319,AFAP1L2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,USP2,RAB3B,CRIM1,CYTH3,GRID1,PRRG1,PHACTR2,ARHGAP32,TLR6,LEPR,MAP1B,GPR37,MYADM,EDA,RND3,GCSAM,MPP7,PRCP,CTSV,SLC7A5,SLC18B1,KIF21A,GEM,IL9R,MMP16,SLC16A10,ABCG1,SNPH,STOM |
| 4.139e-17 | -37.72 | classic | COSMIC cancer mutations | classic | 15207 | 1586 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 5.524e-17 | -37.43 | desmoplastic | COSMIC cancer mutations | desmoplastic | 15212 | 1586 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 7.056e-17 | -37.19 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | 1003 | 181 | 17385 | 1698 |
SIDT1,ATP8A1,UGDH,MCOLN3,NPM1,CADM2,ITPR2,PRKCA,IKZF2,DNER,HMCN1,FSTL5,NOS1AP,PCDH7,TGFBR3,KCNN2,PPFIA2,ANKFN1,CHRDL1,COL19A1,ATRNL1,MYRIP,ETV1,SLIT2,NEB,RASGRP1,TBC1D8,PGBD5,EML6,CAP2,KLHL4,CAPN5,MEF2B,INTS6,GPC6,TMEM132B,MAP2,NCAM2,TPM1,PPARGC1A,MAGI2,HS6ST3,KCNV1,MOCOS,EHHADH,SEC24D,UBASH3B,GABRB2,OPHN1,SETBP1,GALNT13,FAM81A,FHOD3,MTUS1,EFEMP1,IGF1R,FRY,CNTN4,PIK3AP1,FRAS1,PDE10A,EBF4,PRKG1,GAN,CPXM2,MPDZ,TSPAN12,NCAM1,FAM155A,PRR16,AGL,LRP12,PCDH10,UNC5C,PNP,COL4A4,TCEA3,RYR2,ST6GALNAC3,CCDC85A,SDK1,B4GALNT3,KHDRBS2,NEGR1,TBC1D2,CACHD1,GRIK4,TEX15,SH3GL2,ADAMTS3,CECR2,C1orf21,MATN2,RAB31,TMEM117,CLMN,LAPTM4B,PTPRN2,OSBPL6,MME,DOCK9,CXCR5,ZSWIM5,DNM3,DOCK1,MSR1,BCL6B,IL13RA1,LCP2,RADIL,PIBF1,DOCK2,PCLO,TBC1D19,ZNF827,SPEG,PDZD8,FAM155B,POU2F2,DNAH5,SCN3A,KCNB2,SHANK2,ADCY1,NLGN4X,SATB2,RAB38,CD40,TTC28,METAP1D,SMAD3,ENTPD1,ARHGAP21,RANBP2,NRG3,PDLIM3,PEMT,INPP4B,GRB10,RNF130,HS3ST3B1,NR3C2,STON2,MID1,COBL,CTNND2,CCDC148,WDR17,ROBO2,C1orf226,PSD3,HERC5,NKAIN2,NEDD4,CHN2,GPR155,AFF2,DSG2,GTF2F2,KIAA0319,FIG4,TNFRSF11A,MED12L,DUSP1,BCL7A,AGPAT4,ATP11A,ZFPM2,NAALADL2,SMPDL3B,DDAH1,DOCK7,PLOD2,MPP7,PLXDC2,UACA,ZNF808,TBC1D4,MMP16,ATP2B4,CACNA2D1 |
| 8.392e-17 | -37.02 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | 15206 | 1585 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 8.392e-17 | -37.02 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 15206 | 1585 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 8.392e-17 | -37.02 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 15206 | 1585 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH,STOM |
| 8.392e-17 | -37.02 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | 15206 | 1585 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 1.117e-16 | -36.73 | medulla | COSMIC cancer mutations | medulla | 15211 | 1585 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH,STOM |
| 1.282e-16 | -36.59 | chondroblastoma | COSMIC cancer mutations | chondroblastoma | 553 | 118 | 17385 | 1698 |
ARHGAP26,PHACTR3,ACSL1,DNM3,CACNG3,CNTNAP3,RHPN2,ENAH,KIAA1217,CA8,DOCK2,HMCN1,FSTL5,PCDH7,FKBP9,ZFYVE28,TACC2,COL25A1,PPFIA2,ZNF521,COL19A1,ATRNL1,FHIT,PPP2R2B,PCOLCE2,COG3,MET,TLN2,TLR4,TSHR,SNX10,SLIT2,KCNB2,INTU,GPM6A,KCNIP3,EVL,DCC,FGF12,ADCY1,PREX1,RAB38,ZDHHC14,TTLL7,GPC6,ARMC4,NRG3,KCNMB4,GYPC,PRKCB,CCBE1,RASGRF2,NCOA7,ARHGAP28,TMEFF2,COBL,CTNND2,HS6ST3,FARP1,MRC2,REL,NSUN6,CLSTN2,NKAIN2,GALNT13,CREB5,WDFY4,TPD52L1,FHOD3,SLC35F1,CHN2,IGF1R,FAM189A1,FRAS1,PRKG1,SLCO4C1,FMNL2,KIAA1211,HMGCR,DLGAP1,VAV3,SLC36A1,RNF170,CRIM1,COL4A4,ESRRG,CYTH3,GRID1,MARS,ST6GALNAC3,SDK1,SNTB1,ZFPM2,PALLD,B4GALNT3,PLCB1,KHDRBS2,NAALADL2,SMPDL3B,NEGR1,CTIF,GPR37,BEX4,DDAH1,PLEKHH2,SH3GL2,PLOD2,FBN1,PELI2,LRRIQ3,TMEM117,PTPRN2,LAPTM4B,PLD1,SEMA3A,TBC1D4,CDH2,XKR4 |
| 2.115e-16 | -36.09 | locomotion | biological process | GO:0040011 | 1179 | 200 | 17256 | 1658 |
ACVR1,FGF13,KIF5A,JCHAIN,GATA3,ENAH,STAT5B,PRKCA,DNER,RAC3,SKI,EPCAM,RND2,TYMP,TGFBR3,LRRC6,DNAH6,ITGB3,CTTN,ETV1,PLTP,SLIT2,POU3F3,PDGFRB,NKX2-1,CYP1B1,CFAP44,TNK2,ITGB7,GPM6A,SLC3A2,MARK1,DCC,SLC9C1,LRRK2,FEZ1,EFHC1,TNS1,GPC6,SPNS1,NCKAP1L,SEMA3C,PIK3C2B,NRP1,UNC5B,TMEFF2,SLC9B1,MEF2C,BCL11B,EFNB2,TYRO3,FN1,LGALS3,CELSR1,BVES,ITGA6,OPHN1,FOXG1,DOK5,DDIT4,MCOLN2,CHN1,NAV1,CNTN4,SLC7A11,SEMA4F,GATA2,FLRT3,PRKG1,NCAM1,JAM2,GFRA1,LRP12,NOS3,EPB41L5,PAK1,FGFR4,DPYSL5,UNC5C,BDNF,DISC1,PODXL2,RHOQ,VLDLR,ARID5B,DCHS1,EFNA3,SPATA13,SDC3,WWC1,CDC42BPA,RIPOR2,PKN3,THBS4,FAT1,MATN2,PLD1,CDH2,SEMA3A,SIX2,SHTN1,CXCR5,EPHA3,AMOTL1,ID1,RHOD,DOCK1,CELSR3,RBFOX2,PSTPIP2,PLXNA2,ADD2,NTRK3,NRXN1,COLEC10,DDR1,SEMA6A,DOCK2,CTNNA2,GPR15,PLPP1,LHX6,DAB2IP,PDE4D,PROS1,MET,DNAH5,SNAI2,DOCK8,SEMA6C,GAB2,FER,EVL,FZD4,PTPN6,PREX1,PRKCQ,WNT11,SATB2,ATP1B1,RARRES2,ATOH1,FRK,JAM3,CENPV,FGFR1,IRS2,CXCL10,NRG3,PTPRJ,GYPC,APELA,PTK7,LAMB1,ITGA2,HGF,GRB10,HOXB9,ROBO2,GRB14,PAK5,EPS8,CMTM8,KIF5C,SELL,GAS6,P2RY1,OVOL2,PKN1,EPHB1,NEDD4,NEO1,NKX6-1,SCN1B,PRKCD,KIAA0319,TNFRSF11A,SYK,FES,PARP9,PDLIM7,TRPM4,VEGFC,VAV3,PXN,RAPGEF2,NR4A1,ASAP3,PALLD,PEAK1,MAP1B,RERE,GPLD1,GPR37,PTPRC,FGR,RND3,SLC7A5,BMP4,ATP2B4 |
| 3.139e-16 | -35.70 | kidney-other-neoplasm | COSMIC cancer mutations | kidney-other-neoplasm | 10949 | 1220 | 17385 | 1698 |
ARHGAP26,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,DCC,DSTN,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ERCC5,INPP5F,CAB39L,TMOD2,DNHD1,VASH2,SCN5A,TMEM63C,ZNF25,TJP1,GPSM2,BBS9,CHN1,FRY,APLF,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,SLC19A2,ALDH1L1,RPL26L1,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADCY1,WNT11,DSP,ASPH,ZNF618,GABARAPL1,ARHGAP21,PDLIM3,LAMB1,LRRC27,RAB30,CCDC148,WDR17,CKAP2,BACE1,UBAC2,PSD3,CBS,HMGCS1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,CPNE2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,MARK1,KCNIP3,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,SESN1,CRYBG3,SPNS1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,ZNF215,ZIC2,DOK5,FHOD3,NUMBL,GALNT1,ZNF440,FRAS1,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,OBSCN,SDK1,KHDRBS2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,IGFBP3,RPS13,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,MAOA,HGF,MBOAT2,CTNND2,TENM1,SLC6A9,NECAB2,BMPR2,MCTP2,USP30,SLC35F1,TTC1,KCNMB3,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,ATP2B1,CES3,FOXN3,FERMT2,PALLD,EXOG,ILDR2,HOMER3,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,PTGES,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,NDUFB8,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,SERPINI1,DSEL,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,PRKG1,SREBF1,CPXM2,GRIP1,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,MMP15,PLEKHH2,PELI2,THBS4,C1orf21,LRRIQ3,MPP2,DYNC2LI1,SQLE,SFMBT1,TCTN2,ST14,CCDC110,MSR1,PLXNA2,TMEM170B,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,PYGO1,ATP1B1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,COBL,PURG,STON2,MID1,HACE1,MYO1D,PLSCR4,EPS8,HERC5,NDFIP2,TPD52L1,INPP1,IRX5,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,VAV3,ARHGEF28,SH3BP2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,SVIL,CERS1,LARP1,ACSL1,UGT8,PTPN21,C20orf194,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,PPM1E,SIPA1L2,ANKFN1,CNNM2,TRPC1,MYRIP,IL1RAP,PDGFRB,LAMP3,SESN2,SKAP2,JPH1,YAP1,COTL1,SGK2,TMEM150B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,GPT2,SV2B,MOCOS,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,SDC3,SLC46A3,HERPUD1,TMEM154,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,PDZD8,KAZN,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,MVD,CD40,CENPV,BATF3,BCL11A,ZNF569,ARMC4,ZNF93,KPNA3,RBPMS2,TMPRSS9,RGS10,DUSP19,RNF130,ENO2,ARHGEF11,TSPAN15,CMTM8,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,SYDE2,MCU,RAB11FIP5,SCN1B,STC2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,CARD6,USP2,CRIM1,SYBU,ASAP3,GALNT14,NAALADL2,LRAT,CTIF,DPY19L2,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,DNAJC3,CADM2,DOCK3,NHP2,CA8,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,DNAH6,FAAH2,PPFIA2,TSHR,RWDD2A,MEIS2,CAP2,TGFA,ELMOD1,MFSD6,CA13,ARHGAP28,ZBTB20,TMEFF2,CRYL1,LATS2,STOX2,CYP2J2,TTC30B,SYCP2,RSL24D1,BNIP1,KIAA1671,FAM189A1,BACE2,PRELID2,LOXL4,ST8SIA1,TSPAN9,STXBP1,GLIS1,AGL,FMNL2,LRP12,CHRM3,RPS23,BDNF,SLC37A1,PNP,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,FBXO27,TRPC3,BTC,ZNF516,DNM3,GALNT12,C4A,FAM131C,GALNT6,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,TXNRD3,CDS1,EPB41L3,CHRNA5,KMO,COL25A1,CNKSR3,DACT1,RTKN2,FAM155B,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,IRS2,IQCK,IQCH,GYPC,PEMT,WWTR1,PLEKHG1,RCN3,ALG11,P4HA1,TNFSF15,HOXB9,FARP1,ROBO2,C1QTNF3,IPO5,NKAIN2,CREB5,PKN1,TSPAN17,COL27A1,NEO1,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,DCBLD1,NMNAT3,FAM227A,SYT12,FHDC1,LILRB1,ASS1,NRN1,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,HPS1,MARVELD2,LIN7A,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,SLC3A2,GDPD1,PLEKHA1,TCERG1L,BATF,NT5DC2,PLEKHB1,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,ZCCHC24,UBASH3B,RASL11B,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,KIAA0895,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,SAMD11,BNIP3,SLCO4C1,FBXL2,CHSY3,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,PPFIA4,WDR25,PDE8A,TEX9,LDHD,ATPAF2,PANK3,TESC,MME,CFH,LPCAT2,XYLT1,LPIN3,SEZ6L2,PCLO,CBLN1,TBC1D19,ZDHHC6,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,TMEM67,UROS,THSD4,FGF12,GSTO1,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,GBP1,PTK7,KCNG1,ABI3,ITGA2,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,GRB14,RUSC2,BLVRB,GABRG2,ARHGAP44,PPP2R3A,TECPR1,MAP1A,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,ZNF808,DLG2,SLC22A15,PAX9,TBC1D4,FILIP1,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,AARS,NCS1,STK24,MOK,CFHR1,FAM168A,SLC16A2,CHRDL1,ATRNL1,BEND4,RCAN3,VWA5A,PLTP,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,TNS1,SLC25A28,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,ENTPD7,RASGRF2,CCBE1,SEMA3C,UNC5B,TANC2,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,ZHX3,GABRB2,SCN8A,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,PRRG4,MECOM,MCOLN2,NAV1,KIAA1257,PIK3AP1,RUNDC3B,OPN3,SLC16A9,TSPAN12,MPDZ,SAMD13,RIMS2,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,CCDC85A,RABAC1,PLCB1,ZNF558,DAGLA,XKR9,VPS37D,PMEPA1,ISM1,ANKRD20A5P,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,RASAL2,ELOVL4,RNF144A,ZNF311,CHUK,SPATS2L,NUDT12,ZNF827,TMEM53,MARCKS,ATP6AP1L,VNN2,PDK1,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,ZNF396,PRKCB,KLF5,GRB10,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,WASF3,ANO10,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GDPD5,NEDD4,RGS17,SOAT2,RALGAPA2,SLC6A15,FIG4,GFI1,PFKFB4,ARAP2,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,NUDT17,ATP1A3,SLC43A1,EXPH5,MPZL3,MVK,HEBP1,KIF5A,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,QPRT,CYP51A1,ARHGEF10L,RTN1,LRRC6,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,SEC24D,RIMKLA,ELOVL7,YPEL2,CYP4V2,LAMC3,GALNT13,PHGDH,SATB1,DDIT4,CA2,FAM107B,EBF4,NCEH1,NOS3,GPR176,RAX,MSTN,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,RAI14,HK2,EGFL7,DIRC2,CREB3L2,EML5,NEK10,ZSWIM5,CELSR3,IL15,PLEKHA5,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,MET,SUSD3,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,DOCK5,TTLL7,WARS,TPK1,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,PSPH,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,MSX1,RAB3B,ESRRG,CYTH3,GRID1,OGDHL,PRRG1,MEI1,MARS,PHACTR2,AGAP2,ARHGAP32,ZFPM2,C3orf70,MAP1B,RERE,GPR37,ADAMTS17,NACC2,MPP7,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SLC16A10,STOM,SNPH |
| 3.381e-16 | -35.62 | plasma membrane | cellular component | GO:0005886 | 5251 | 645 | 18223 | 1724 |
DOC2A,TRIM16L,FLVCR2,CNTNAP3,GRIK2,PRSS12,RECK,MCOLN3,CADM2,SNX9,ABHD6,NOS1AP,PCDH7,BAG3,TGFBR3,RAP2A,RAB26,COG3,TSHR,CPE,DCC,CAP2,WLS,GJB2,TGFA,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,F12,SLC7A1,ENPP1,ATP7B,ADRB1,DIRAS1,TPM1,LPP,SCN5A,GNG12,ITGA6,TJP1,SLC36A4,GPSM2,BBS9,BACE2,CACNB2,FLRT3,LMAN2,CADPS2,FAM84B,NCAM1,JAM2,STXBP1,TSPAN9,GFRA1,CHRM3,LRP12,KCNQ3,MYO10,FASN,HIP1,CALCRL,RYR2,SNAP25,OR11H4,ARRDC4,CPEB1,SH3GL2,CDH17,LAPTM4B,CDH2,TRPC3,BTC,DNM3,SCAMP1,C4A,MYO1B,RGS20,PKP2,ADD2,IL13RA1,GRK6,NRXN1,LCP2,SLC19A2,GPR15,EPB41L3,PLPP1,TLR3,GPRIN1,CHRNA5,COL25A1,CNKSR3,ARL4D,FAM155B,RAB27B,KIAA1549,PERP,SCN3A,DOCK8,KCNB2,FZD1,GAPDH,COL6A2,FZD4,KCNH5,ADCY1,RAB38,DSP,ASPH,FGFR1,MAGI3,GABARAPL1,GJC1,SLC39A14,IRS2,ENTPD1,ARHGAP21,CXCL10,GYPC,GPR160,PEMT,PAM,TNFSF15,LRRC27,C2orf88,SERINC5,FARP1,ANKRD13B,EDA2R,ROBO2,FZD8,BACE1,CD276,NKAIN2,PSD3,P2RY1,SLC12A6,PKN1,EPHB1,KCNC4,TSPAN17,NEO1,MCF2L,GHR,NPTXR,MYO6,FES,ULBP1,TRPM4,LZTS3,RAPGEF2,RASA3,GAREM1,ATP11A,RACK1,SNTB1,HEG1,PTPRC,TRIB3,PCDHB7,PLPPR2,GNAO1,SLCO5A1,ATP2B4,CACNG3,TRIM16,FGF13,SYT12,LILRB1,NRN1,ITPR2,SYT14,PLS3,RND2,CPNE2,KCNN2,TM9SF2,KCNAB1,TCAF2,HPS1,MARVELD2,ITGB3,LIN7A,TLN2,TLR4,ENO1,DBN1,ITGB7,SLC3A2,CD55,KCNIP3,ATF4,MARK1,ABCC4,ANK2,PLPP2,CR2,PLEKHA1,TSKU,KCNMB4,AHNAK2,TNFRSF1A,PIK3C2B,ADGRA3,TC2N,TYRO3,KCNV1,RGS16,LGALS3,STXBP5L,ITPRIP,MLC1,IL18R1,SPIRE1,SEMA4F,IGF1R,FRAS1,LRP6,ADCY6,PTPRCAP,SLCO4C1,CKAP4,PAK1,FGFR4,UNC5C,BTNL9,SLC27A2,HOMER2,GPSM1,SPATA13,EFNA3,SLITRK5,OBSCN,SDK1,GPR19,BAIAP2,NEGR1,GRIK4,KCNK15,MFSD2A,CSF1,SLC2A6,PLD1,TESC,MME,AKAP5,OR51B4,NTRK3,SLC7A2,SEZ6L2,PRR7,SEMA6A,CBLN1,CTNNA2,SLC22A17,TACC2,ADGRL1,SCN2A,TMEM67,EVA1A,TMEM65,LRRC8B,CHRNA6,VIM,FRK,JAM3,C4BPB,SMAD3,NRG3,PTPRJ,PTK7,GBP1,KCNG1,ITGA2,PTPRS,SEPT5,CNTN1,TENM1,PCDH18,LPAR2,SLC6A9,NECAB2,BMPR2,GRB14,APBB1,BLVRB,SELL,GABRG2,RASD1,ARHGAP44,RASD2,KCNMB3,SGK1,TSPAN13,KLF9,SYK,SLC45A3,ATP2B1,PCSK6,DLGAP1,LITAF,FERMT2,PALLD,NPDC1,SMPDL3B,HOMER3,DKK1,CD37,FAT4,DLG2,SLC22A15,SLC1A5,FILIP1,CACNA2D1,CGN,ACVR1,LANCL3,LGR4,ATP8A1,VAMP8,LDLR,ENAH,PRKCA,RAC3,NCS1,SLC9A7,SLC16A2,SLC22A18,KCNS3,PACSIN1,GLDC,ACVR1C,SLC9C1,LRMP,ACVR2B,GPC6,GNAI1,GPR150,NCKAP1L,ENPP6,RASGRF2,SPRY4,SPART,UNC5B,NRP1,LZTS1,EFNB2,SEMA6B,INPPL1,MRC2,CELSR1,PTPRD,GABRB2,SCN8A,SLC1A3,TNFRSF10C,APBA1,TNFRSF19,GAS1,MTUS1,MCOLN2,CNTN4,SLC7A11,RALGPS2,MSMO1,PIK3AP1,PDZD7,SCARF2,PRKG1,OPN3,GRIP1,MPDZ,TSPAN12,SLC16A9,FAM155A,GPR161,RIMS2,IGSF3,EPB41L5,DISC1,SLC36A1,DCHS1,RAPGEF4,VLDLR,PACSIN3,TTYH2,RABAC1,DAGLA,MMP15,PLEKHH2,PMEPA1,MPP2,EPHA3,FRMPD3,AMOTL1,RASAL2,TCTN2,RNF144A,RHOD,ST14,GPR65,PLXNA2,MSR1,CHUK,KCTD12,TMEM170B,DDR1,TBC1D30,NBEA,DAB2IP,MARCKS,PDE4D,GAB2,VNN2,SHANK2,PREX1,NLGN4X,PRKCQ,ATP1B1,ATP10D,PATJ,DCBLD2,SNCA,HTR7,IKZF3,POPDC3,PRKCB,ASIC1,MAP3K21,HPGD,GRB10,HS3ST3B1,BMPR1A,MAPK10,COBL,ANO10,MYO1D,PLSCR4,ANKRD13D,GLIPR1L1,ATP9A,EPS8,ARL2,GABRR2,RGS7,SLC35G2,NEDD4,ADGRB2,LRRC55,RGS17,PRKG2,RALGAPA2,SLC6A15,DYNC2H1,ERRFI1,SPRY2,VAV3,SLC40A1,ARHGEF28,PXN,PTPN13,CACNA1E,MPP1,GUCY1A2,SKAP1,FGR,OR2T33,TERT,CLDN12,MCC,SVIL,GRIN2D,TNFRSF17,OCLN,SLC43A1,ATP1A3,UGT8,ACSL1,SLC2A13,DNER,CACNB4,HMCN1,SLCO3A1,KREMEN1,GSDME,F3,CYP51A1,EPCAM,SLC10A7,CNNM2,TRPC1,SLC2A12,CTTN,EPHB6,PTPRE,OR2W3,SLIT2,IL1RAP,PRKACB,PDGFRB,RASGRP1,LAMP3,TNK2,GPM6A,SKAP2,CEMIP2,JPH1,TMEM47,ROR1,GRK3,GSN,TMEM150B,GPRC5B,NCAM2,ITGBL1,OXTR,TNFSF4,MAGI2,APBA2,SLC9B1,GPR63,SV2B,FN1,RHOBTB1,SCART1,BVES,STXBP6,CD7,ADGRG6,PCDHB14,EEF2,CA2,VSIR,NOS3,PCDH10,CDH26,GPR176,IL17RD,RHOQ,PODXL2,SLITRK2,PARD3B,SDC3,WWC1,CATSPERE,STEAP1,RIPOR2,ADGRB3,FCHO2,FAT1,NCR3LG1,RAB31,TMEM117,PTPRN2,DISP2,FNBP1L,OSBPL6,CXCR5,SORBS1,CELSR3,IL15,SCIN,CD53,UNC13B,KAZN,PPFIBP1,MAP7,ACVR2A,STEAP3,FHIT,PROS1,MET,HSPA2,NTNG1,SEMA6C,ALG10B,SUSD3,DPP10,PRAME,PHLDB2,FER,ANTXR2,GCA,PTPRU,PTPN6,SLC39A8,TES,AMIGO1,CD40,DOCK5,CAMK2N1,TMPRSS9,RGS10,DISP1,LIFR,MAST1,OR51B5,TNIK,ENO2,TSPAN15,LRP4,TNFSF13B,CLSTN2,FSD1,KCNJ4,SCN1B,DSG2,PRKCD,EHD3,KIAA0319,AFAP1L2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,RAB3B,CRIM1,CYTH3,GRID1,PRRG1,PHACTR2,ARHGAP32,TLR6,LEPR,MAP1B,GPR37,MYADM,EDA,RND3,MPP7,GCSAM,PRCP,CTSV,SLC7A5,SLC18B1,KIF21A,GEM,IL9R,MMP16,SLC16A10,ABCG1,STOM,SNPH |
| 4.983e-16 | -35.24 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | 472 | 105 | 17377 | 1707 |
CREB3L2,ID1,ADAL,RASAL2,CFH,FGF13,LPCAT2,FHDC1,KCTD12,STAT5B,ABAT,FAM13A,KIAA1217,COL14A1,FAM110B,FKBP11,KCNAB1,ABI3BP,TACC2,SLC16A2,GSTM3,RCAN3,VWA5A,CPE,SLIT2,NEB,FZD1,GPM6A,TMEM67,EIF4E3,SMAD9,PFKFB2,SHANK2,DEPTOR,FEZ1,TNS1,SESN1,GNAI1,ZNF711,GSN,ENPP1,IQCK,SH3RF1,IGIP,WFS1,BDH2,BMPR1A,MAGI2,LIFR,MLLT3,CRYL1,RRAGD,HEY1,MEF2C,UST,WASF3,PCDH18,FARP1,PLSCR4,TBC1D1,PTPRD,STXBP6,ZCCHC24,SLC25A27,CYP4V2,NIPSNAP3B,DOK5,NEO1,MTUS1,IL17D,FRY,KIAA1671,ABCA5,FLRT3,GHR,PRKG1,RALGAPA2,ACTA2,SGK1,TSPAN12,AFAP1L2,SAMD13,KLF9,LOXL4,VGLL4,TNFRSF11A,ZFP36L2,CEBPD,B9D1,SYNPO2,GSTM2,RNF170,PHACTR2,ST6GALNAC3,CLN5,FAM162A,RERE,BEX4,CACHD1,NSD1,RIMKLB,MATN2,SH3BGRL2,PKIA,STOM |
| 5.261e-16 | -35.18 | HELLER_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_SILENCED_BY_METHYLATION_DN | 98 | 40 | 17377 | 1707 |
RGS16,CLGN,SEC24D,CBS,CHAC1,PHGDH,TXNDC5,DDIT4,CDS1,BAG3,RPS6KA2,ASNS,CA2,SLC7A11,MYC,PPFIBP1,SLC6A15,SERPINH1,SLCO4C1,PLTP,TSHR,CTH,SLC3A2,ATF4,ATF3,MARS,MAP1B,WARS,CEBPB,PTPRC,DDAH1,TRIB3,EIF4EBP1,INHBE,FAM149A,HGF,PPARGC1A,TNFRSF17,MMP16,DDIT3 |
| 6.040e-16 | -35.04 | movement of cell or subcellular component | biological process | GO:0006928 | 1416 | 228 | 17256 | 1658 |
ACVR1,FGF13,KIF5A,JCHAIN,GATA3,ENAH,STAT5B,PRKCA,DNER,RAC3,SKI,EPCAM,RND2,TGFBR3,LRRC6,KCNN2,DNAH6,ITGB3,CTTN,MYRIP,ETV1,PLTP,SLIT2,NEB,POU3F3,RASGRP1,PDGFRB,NKX2-1,CYP1B1,CFAP44,TNK2,ITGB7,GPM6A,SLC3A2,MARK1,DCC,SLC9C1,ANK2,LRRK2,FEZ1,EFHC1,TNS1,KCND3,GPC6,WIPF3,NCKAP1L,SEMA3C,PIK3C2B,TPM1,NRP1,DNHD1,UNC5B,TMEFF2,SLC9B1,MEF2C,BCL11B,EFNB2,TYRO3,SCN5A,FN1,LGALS3,CELSR1,BVES,ITGA6,OPHN1,APBA1,DYNC1I1,FOXG1,TTC30B,DOK5,DDIT4,MCOLN2,CHN1,NAV1,CNTN4,SLC7A11,SEMA4F,GATA2,CACNB2,FLRT3,PRKG1,NCAM1,JAM2,GFRA1,LRP12,NOS3,EPB41L5,PAK1,DPYSL5,FGFR4,UNC5C,BDNF,DISC1,PODXL2,RHOQ,MYO10,VLDLR,ARID5B,DCHS1,EFNA3,SPATA13,RYR2,SDC3,WWC1,TTC30A,CDC42BPA,SH3GL2,PKN3,THBS4,FAT1,WDR19,MATN2,DYNC2LI1,PLD1,FNBP1L,SEMA3A,CDH2,SIX2,SHTN1,CXCR5,EPHA3,AMOTL1,ID1,RHOD,DOCK1,CELSR3,RBFOX2,PSTPIP2,MYO1B,PLXNA2,ADD2,PKP2,NTRK3,KIF21B,NRXN1,DDR1,SEMA6A,CTNNA2,GPR15,PLPP1,LHX6,MYO3B,DAB2IP,MYH15,PDE4D,PROS1,DNAH5,SNAI2,DOCK8,SEMA6C,GAB2,FER,EVL,PTPN6,PREX1,FGF12,VIM,PRKCQ,WNT11,SATB2,ATP1B1,ATOH1,FRK,JAM3,CENPV,FGFR1,GJC1,IRS2,ARMC4,ARHGAP21,CXCL10,IFT81,NRG3,GYPC,APELA,PTK7,ITGA2,LAMB1,HGF,GRB10,HOXB9,MYO1D,ROBO2,GRB14,PAK5,EPS8,KIF5C,SELL,GAS6,P2RY1,OVOL2,PKN1,EPHB1,NEO1,NKX6-1,MAP1A,SCN1B,PRKCD,KIAA0319,DYNC2H1,MYO6,TNFRSF11A,SYK,FES,PARP9,PDLIM7,TRPM4,VEGFC,VAV3,PXN,RAPGEF2,NR4A1,SYBU,ASAP3,PALLD,PEAK1,MAP1B,RERE,GPLD1,PTPRC,FGR,RND3,SLC7A5,DLG2,KIF21A,KIF1B,ATP2B4,CACNA2D1 |
| 7.002e-16 | -34.90 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 15815 | 1627 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,RBM11,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 8.201e-16 | -34.74 | HOELZEL_NF1_TARGETS_UP | MSigDB lists | HOELZEL_NF1_TARGETS_UP | 127 | 46 | 17377 | 1707 |
ARHGAP26,TNIK,RGS16,LGALS3,PRSS12,GRIK2,PLEKHA5,EPS8,CLSTN2,HBE1,SPATS2L,SYT14,NRXN1,NUP62CL,SEL1L3,PHLDA2,FSTL5,PCDH7,PLS3,NAV1,CPVL,STEAP3,MET,CHRM3,B4GALT6,ANK2,THSD4,DEPTOR,PHACTR2,TMEM74,CPEB1,DCBLD2,CEBPB,PDLIM3,NACC2,RND3,MAP2,PLK2,ITGA2,RAB31,AHNAK2,HGF,HS3ST3B1,OSBPL6,HEY1,HS6ST3 |
| 1.016e-15 | -34.52 | cell morphogenesis | biological process | GO:0000902 | 677 | 132 | 17256 | 1658 |
UGT8,KIF5A,GATA3,ENAH,PRKCA,RAC3,STK24,ITGB3,POF1B,CTTN,PACSIN1,ETV1,SLIT2,NKX2-1,ATL1,ITGB7,GPM6A,DCC,CAP2,LRRK2,YAP1,FEZ1,ARHGEF26,TSKU,NCKAP1L,MAP2,SEMA3C,NRP1,UNC5B,MEF2C,BCL11B,EFNB2,TYRO3,LRFN5,FN1,BVES,OPHN1,LAMC3,SLC1A3,FOXG1,DOK5,CHN1,NUMBL,CNTN4,FRY,SEMA4F,PDZD7,FLRT3,NCAM1,STXBP1,GFRA1,ZNF385A,EPB41L5,PAK1,DPYSL5,CDH26,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,STRADB,BAIAP2,SH3GL2,WDR19,MATN2,NKX2-8,CDH2,SEMA3A,SHTN1,TFCP2L1,NBL1,ID1,ST14,CELSR3,RBFOX2,PLXNA2,COL18A1,NRXN1,RADIL,DDR1,SEMA6A,CTNNA2,EPB41L3,COL25A1,BCL6,DAB2IP,MET,ZNF365,NTNG1,SEMA6C,GAB2,FER,EVL,FZD4,PTPN6,SHANK2,ADCY1,PRKCQ,ATOH1,AMIGO1,IRS2,LAMB1,HGF,GRB10,COBL,CTNND2,TENM1,TNIK,FARP1,ROBO2,APBB1,LRP4,KIF5C,EPHB1,NEO1,LRRC55,MAP1A,LRRN1,SCN1B,SGK1,PDLIM7,MSX1,FERMT2,PALLD,PEAK1,RERE,MAP1B,HEG1,DKK1,DOCK7 |
| 1.212e-15 | -34.35 | oesophagus-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-carcinoma-squamous_cell_carcinoma | 6668 | 804 | 17385 | 1698 |
THOC5,FLVCR2,GRIK2,AASS,CNTNAP3,RECK,NPM1,CADM2,BCAN,KIAA1217,CA8,EYA4,SKI,BAG3,FBXO32,TGFBR3,DNAH6,PPFIA2,RAB26,COG3,CPE,TSHR,NKX2-1,MEIS2,SMAD9,DCC,EXOC6B,CAP2,DSTN,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,F12,INTS6,CA13,SLC7A1,WIPF3,ATP7B,ALDOA,BDH2,ADRB1,ARHGAP28,ERCC5,INPP5F,ZBTB20,DNHD1,TMEFF2,CARS,SCN5A,LATS2,TMEM63C,CYP2J2,ITGA6,TJP1,SLC36A4,FOXG1,BBS9,CHN1,SYCP2,FRY,BACE2,APLF,FAM189A1,CACNB2,FLRT3,ZIC5,PRELID2,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,ST8SIA1,DENND1C,FIGN,JAM2,AGL,GLIS1,STXBP1,LRP12,CHRM3,HMGCR,SLC37A1,KCNQ3,MYO10,STAT4,SPATA6,MGST3,ARID5B,EFHC2,FASN,FHL2,RYR2,HIP1,PLS1,AIG1,ST6GALNAC3,ZBBX,TAF4B,SPATA7,CACHD1,TEX15,TMCO3,RIMKLB,ADAMTS3,EMILIN2,CLMN,TRPC3,DOCK9,DNM3,MYO1B,LRRCC1,RGS20,BEGAIN,PKP2,ADD2,COLEC10,LCP2,NRXN1,EPB41L3,TLR3,GPRIN1,ALDH1L1,FAM133A,RTKN2,FAM155B,ARL4D,RAB27B,JAKMIP3,DNAH5,KCNB2,ANKRD18B,SCN3A,DOCK8,FZD1,DZANK1,MYLK3,COL6A2,RNF145,NECAB1,PFKFB2,FZD4,KCNH5,TRAM1L1,ADCY1,TTC28,DSP,ZNF618,FGFR1,IRS2,ARHGAP21,GYPC,GPR160,WWTR1,LAMB1,INPP4B,PAM,P4HA1,ALG11,FAM149A,CCDC148,FARP1,TMEM132C,ANKRD13B,WDR17,EDA2R,GCAT,CD276,ESRP1,PLAG1,IPO5,C1orf226,PSD3,CBS,CREB5,EPHB1,ZNF219,KCNC4,COL27A1,NEO1,GAS2L3,MYO6,ZFP36L2,MED12L,B9D1,RAPGEF2,ELOVL3,RASA3,ATP11A,SNTB1,HEG1,GALNT3,NSD1,PCDHB7,PLOD2,SRD5A3,SLCO5A1,NEK11,BMP4,CMPK2,SHOX2,DOCK6,ATP2B4,CRISPLD1,PHC1,TLL2,NMNAT3,FAM227A,ASS1,NDRG2,LILRB1,MGAT5B,ITPR2,SYT14,NUP62CL,NOVA1,FSTL5,CCNJ,FKBP9,RPS6KA2,EOMES,CPVL,KCNAB1,SEC16B,KCNN2,HPS1,MARVELD2,ITGB3,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TLR4,ETV1,NEB,PGBD5,ZNF391,DBN1,ITGB7,SLC3A2,GCNT2,MARK1,ATF4,ABCC4,COL4A3,ANK2,TMEM200C,CR2,TCERG1L,SESN1,PLEKHB1,SPNS1,DYRK1B,FHAD1,INHBC,KCNMB4,MAP2,P4HA2,GNB4,TECPR2,ERN1,CCDC146,AHNAK2,PIK3C2B,MLLT3,TC2N,KCNV1,STXBP5L,ZCCHC24,SETBP1,MLC1,IL18R1,PGAP1,DOK5,KIAA1958,KIAA0895,ZBTB38,IGF1R,ABCA5,BCHE,ZNF440,GATA2,FRAS1,PDE10A,HS3ST5,LRP6,ADCY6,SLCO4C1,FBXL2,VGLL4,FGFR4,CHSY3,UNC5C,HOMER2,MGAT4B,EFNA3,WDR25,MAFB,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,TEX9,GPR19,NEGR1,TBC1D2,NAP1L5,GRIK4,KCNK15,SEMA3A,CFH,AKAP5,DOCK1,RBFOX2,RHPN2,OR51B4,SLC7A2,FAM198B,KIF21B,LPIN3,DENND3,FAM110B,PPP1R9A,SEMA6A,PCLO,DDX60L,CYP26A1,TBC1D19,FAM131B,TACC2,ZDHHC6,LHX6,MYO3B,BCL6,EEPD1,ZDHHC23,MYH15,CLVS2,SCN2A,CTH,GLI1,HRASLS,INTU,TMEM67,ACO1,FGF12,VIM,SMAD3,IFT81,NRG3,ANKRD31,PTK7,ITGA2,KCNG1,PTPRS,HGF,TTC39A,ZNF701,CTNND2,CNTN1,HEY1,TENM1,COL9A3,PCDH18,DYRK3,BMPR2,GABRG2,SELL,USP30,ARHGAP44,SLC35F1,TECPR1,MAP1A,KCNMB3,TFAP2A,TSC22D1,KIAA0408,SH3PXD2B,SYK,KIAA1211,CES3,PPP1R3D,MICAL2,LRRIQ1,FOXN3,NUAK2,FERMT2,TGDS,FNDC3A,PALLD,HOMER3,DKK1,EBF1,CD37,DOCK7,TMEM237,FAT4,FBN1,FMO4,DLG2,ZNF474,RPL4,KIF1B,CACNA2D1,PKIA,FILIP1,ZNF235,FAM171B,MYCBP2,CGN,ACVR1,PPP4R4,LGR4,TCP11L2,ATP8A1,PRKCA,DACH2,AARS,SLC9A7,HECTD2,STK24,TRPS1,C1orf53,KCNS3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,THSD1,TBC1D8,GLDC,GDAP1,EML6,WISP3,KLHL4,ALDH1L2,DNAJC6,SLC25A28,TNS1,EFHC1,ACVR2B,ZDHHC14,ARHGEF26,GPC6,GNAI1,AHRR,SH3RF1,NCKAP1L,PLK2,ENTPD7,RASGRF2,BMP1,SEMA3C,SPRY4,NRP1,TANC2,UNC5B,LZTS1,LRFN5,MRC2,INPPL1,FAM124A,CELSR1,EHHADH,PTPRD,ZHX3,TBC1D1,GABRB2,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,WDFY4,ADSSL1,TNFRSF19,NIPSNAP3B,MECOM,MTUS1,ABLIM1,CNTN4,ADCK1,NOVA2,PIK3AP1,C1QL4,VWDE,RUNDC3B,PRKG1,CPXM2,GRIP1,MPDZ,TSPAN12,FAM155A,COL9A2,GPR161,RIMS2,IGSF3,PTCH2,DISC1,TBC1D8B,COL4A4,VLDLR,DCHS1,KIAA1324L,TTC30A,PEX5L,CCDC85A,CDC42BPA,PLCB1,FAM162A,DAGLA,PELI2,CECR2,THBS4,LRRIQ3,MATN2,MPP2,SFMBT1,AMPD1,FRMPD3,EPHA3,PLA2G4A,NBL1,AMOTL1,TCTN2,RASAL2,ST14,RNF144A,CCDC110,MSR1,SPATS2L,NUDT12,COL14A1,ZFYVE9,TIAM2,CCDC120,NELL2,ZNF827,SPEG,ZNF438,SHF,NBEA,DAB2IP,NAP1L3,PDE4D,SERPINH1,GAB2,VNN2,SFXN4,NLGN4X,PRKCQ,PYGO1,ATP1B1,TBC1D16,ATP10D,ZNF396,ZNF711,PRKCB,CCNA1,MAP3K21,GRB10,CTTNBP2,NR3C2,STON2,COBL,DENND5B,WASF3,PLSCR4,ATP9A,EPS8,KIF5C,GPR180,RGS7,GDPD5,INPP1,AFF2,RALGAPA2,DYNC2H1,TBC1D9,ERRFI1,SPRY2,PFKFB4,VAV3,ALDH2,ARAP2,SYNPO2,ZDHHC15,CTTNBP2NL,GUCY1A2,SKAP1,HOXA1,ZIC1,GPLD1,ZFP62,FGR,TERT,CLDN12,SVIL,PGM2L1,GRIN2D,MYOM2,TNFRSF17,CERS1,OCLN,DDIT3,B4GALT7,NUDT17,EXPH5,KIF5A,UGDH,PTPN21,C20orf194,ANKRD18A,ABAT,RBM11,IKZF2,HMCN1,SLCO3A1,CHST10,CEP85L,F3,ARHGEF10L,PPM1E,SIPA1L2,LRRC6,AKAP7,DLX6,ANKFN1,POF1B,CTTN,PCOLCE2,MYRIP,OR2W3,IL1RAP,SLIT2,PRKACB,PDGFRB,CYP1B1,GPM6A,CAPN5,JPH1,ROR1,TMEM132B,ITGBL1,NCAM2,CCDC169,NCOA7,PPARGC1A,APBA2,MAGI2,FRMD5,PCSK5,BCL11B,GPR63,ZNF395,FN1,OTOGL,RHOBTB1,SEC24D,JDP2,CYP4V2,GALNT13,CHSY1,SPINK5,PHGDH,SATB1,PCDHB14,CA2,ZNF354A,EBF4,LIMCH1,RNF148,NCEH1,CEBPD,SNX7,NOS3,CDH26,PCDH10,IL17RD,SH2D2A,PARD3B,WWC1,PRDM1,B4GALNT3,GLCE,PLAGL1,FAT1,RAI14,PTPRN2,DISP2,OSBPL6,CREB3L2,DMXL2,EML5,ZSWIM5,SORBS1,CELSR3,PSTPIP2,PLEKHA5,ARHGAP22,HECW2,MORC4,COL18A1,COBLL1,DOCK2,ZSCAN5A,SCIN,CD53,COL22A1,KCTD15,UNC13B,CDC14B,RPS6KL1,KAZN,PPFIBP1,ZNF521,STEAP3,PROS1,MDH1B,WWC2,MET,POU2F2,TMEM120B,HSPA2,SEMA6C,DPP10,ANTXR2,PHLDB2,FER,GCA,PTPRU,TCEAL3,CD40,TTLL7,DOCK5,C1orf174,TPK1,BCL11A,ARMC4,ZNF93,LMLN,BACH2,TRIM34,TMPRSS9,SOHLH2,DISP1,CYP2U1,LIFR,TNIK,ARHGEF11,REL,NSUN6,TNFSF13B,CLSTN2,COL4A5,IGF2BP2,NOTUM,FAM174B,SEL1L3,BMP6,MCU,FSD1,KCNJ4,CHN2,PRKCD,DSG2,EHD3,KIAA0319,ACTA2,TRIM3,AFAP1L2,IQGAP3,PNMA2,RIN2,CARD6,MSX1,HNF4G,CRIM1,ESRRG,GRID1,ASAP3,AGAP2,CCNG1,ARHGAP32,ZFPM2,GALNT14,NAALADL2,LRAT,LEPR,MAP1B,CTIF,GPR37,DPY19L2,ADAMTS17,ICA1,EDA,THSD7B,KIF21A,MMP16,ABCG1 |
| 1.254e-15 | -34.31 | cell junction | cellular component | GO:0030054 | 1256 | 205 | 18223 | 1724 |
ARHGAP26,DOC2A,CGN,FGF13,GRIK2,SYT12,NPM1,ENAH,NRN1,CTBP2,CADM2,HMCN1,NCS1,EPCAM,TCAF2,MARVELD2,ITGB3,LIN7A,POF1B,CTTN,TLN2,PACSIN1,PDGFRB,DBN1,TNK2,ANK2,GJB2,LRRK2,CAPN5,NFIA,ABCC2,TNS1,TMEM47,TRIM9,GSN,OXTR,SPRY4,NRP1,MAGI2,LZTS1,FRMD5,LPP,EFNB2,SV2B,SCN5A,MRC2,BVES,GABRB2,ITGA6,STXBP6,OPHN1,SORBS3,TJP1,MLC1,RPL13A,RPS11,FLRT3,SCARF2,GRIP1,MPDZ,CADPS2,JAM2,TSPAN9,CHRM3,RIMS2,EPB41L5,PAK1,FGFR4,CDH26,UNC5C,DISC1,PARD3B,HOMER2,FHL2,SNAP25,CDC42BPA,SDK1,RABAC1,C4orf19,STEAP1,BAIAP2,CPEB1,TBC1D2,GRIK4,FAT1,CDH17,RAI14,PTPRN2,CDH2,MME,CSRP2,DMXL2,AMOTL1,SORBS1,C4A,ARHGAP22,PKP2,KCTD12,SLC7A2,LCP2,NRXN1,TNKS1BP1,PRR7,PCLO,PPP1R9A,CBLN1,CTNNA2,CD53,SCIN,EPB41L3,CHRNA5,UNC13B,DACT1,PPFIBP1,KAZN,ADGRL1,MARCKS,SCN2A,SYNGR3,PERP,RPS13,FZD1,PHLDB2,FER,EVL,FZD4,TMEM65,PTPRU,TES,PTPN6,SHANK2,CHRNA6,NLGN4X,VIM,ATP1B1,DSP,JAM3,MAGI3,SNCA,GJC1,PATJ,CAMK2N1,ARHGAP21,LMLN,PTPRJ,GYPC,PTK7,ITGA2,FAAP20,PTPRS,STON2,CTNND2,FARP1,BMPR2,EPS8,ARL2,GABRG2,PSD3,GABRR2,ARHGAP44,RGS17,KCNJ4,SCN1B,PRKCD,EHD3,DSG2,SH3PXD2B,YBX3,IQGAP3,SEPT3,RRAS2,FES,PDLIM7,DLGAP1,LZTS3,SYNPO2,PXN,RAPGEF2,CYTH3,ASAP3,GRID1,FERMT2,ARHGAP32,PALLD,SNTB1,SKAP1,PEAK1,HEG1,HOMER3,MAP1B,PTPRC,DOCK7,ICA1,RPL12,MYADM,RND3,MPP7,CLDN12,SVIL,GRIN2D,DLG2,RPL4,NPHP1,OCLN,SNPH |
| 1.360e-15 | -34.23 | lower_third | COSMIC cancer mutations | lower_third | 8160 | 952 | 17385 | 1698 |
ARHGAP26,DOC2A,GXYLT2,THOC5,GRIK2,AASS,CNTNAP3,PRSS12,RECK,TUBE1,FAM102B,NPM1,STAT5B,CTBP2,CADM2,CHAC1,DOCK3,KIAA1217,SNX9,CA8,EYA4,PCDH7,EPDR1,BAG3,IKZF5,DNAH6,PPFIA2,RAB26,TMED9,COG3,CPE,KLHL29,TSHR,NKX2-1,MEIS2,SMAD9,DCC,EXOC6B,TGFA,GJB2,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,MFSD6,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,ARHGAP28,ERCC5,DIRAS1,ZBTB20,CAB39L,DNHD1,TMEFF2,MEF2C,SCN5A,GNG12,TMEM63C,STOX2,ITGA6,ZNF25,TJP1,SLC36A4,BTBD9,FOXG1,BBS9,TTC30B,SYCP2,FRY,KIAA1671,BACE2,CACNB2,FLRT3,ZIC5,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,ST8SIA1,DENND1C,NCAM1,ZNF518B,JAM2,TSPAN9,GFRA1,LRP12,CHRM3,ZNF385A,HMGCR,FADS1,BDNF,SLC37A1,KCNQ3,MYO10,STAT4,FASN,FHL2,RYR2,HIP1,CALCRL,PLS1,C1R,ST6GALNAC3,ZBBX,TAF4B,OR11H4,MBNL2,CLN5,C11orf45,DHX32,BEX4,CACHD1,TEX15,TMCO3,RIMKLB,SH3GL2,ADAMTS3,QPCTL,EMILIN2,CLMN,CDH2,DOCK9,MTG1,NUDT10,ZNF516,FAM131C,MYO1B,LRRCC1,RGS20,BEGAIN,PKP2,ADD2,GRK6,COLEC10,NRXN1,SLC19A2,TXNRD3,EPB41L3,TLR3,CHRNA5,CNKSR3,COL25A1,DACT1,ALDH1L1,PJA1,FAM155B,RPL26L1,SYNGR3,ZNF365,DNAH5,MYT1,KCNB2,SCN3A,FZD1,DZANK1,SSH3,MYLK3,GARS,COL6A2,RNF145,NECAB1,KCNH5,TRAM1L1,ADCY1,TTC28,DSP,ASPH,METAP1D,FGFR1,SLC39A14,ARHGAP21,IQCH,GPR160,WWTR1,LAMB1,INPP4B,PAM,PLEKHG1,P4HA1,ALG11,PLD5,DBP,KLHL31,SERINC5,C2orf88,CCDC148,FARP1,WDR17,C1QTNF3,ROBO2,EDA2R,CKAP2,FZD8,CD276,IPO5,UBAC2,NKAIN2,PSD3,CBS,CREB5,PKN1,EPHB1,ZNF219,KCNC4,COL27A1,HMGCS1,LRRN1,GHR,ZFP36L2,MED12L,PARP9,TRPM4,MN1,BCL7A,LCA5,MCF2L2,RAPGEF2,AK4,RASA3,ATP11A,SNTB1,HEG1,GALNT3,PTPRC,NSD1,RPL12,PCDHB7,SLCO5A1,NEK11,BMP4,HK1,SHOX2,CRISPLD1,FOXA1,PHC1,TLL2,PHACTR3,CACNG3,TRIM2,FGF13,FAM227A,SYT12,LMCD1,ASS1,ITPR2,FAM13A,NOVA1,FSTL5,PLS3,RND2,RUFY4,CPNE2,FKBP9,RPS6KA2,TM9SF2,SEC16B,KCNN2,HPS1,MARVELD2,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TMEM132E,ETV1,TLR4,RAPGEF5,NEB,ZNF391,SLC3A2,MARK1,ABCC4,COL4A3,ANK2,CR2,TCERG1L,SESN1,CRYBG3,TSKU,SPNS1,TRIM9,TCF7L1,KLF12,MAP2,P4HA2,GNB4,TECPR2,ERN1,CCDC146,AHNAK2,PIK3C2B,TC2N,RRAGD,LONRF1,PRKAA2,KCNV1,RUNX2,STXBP5L,UBASH3B,SETBP1,RASL11B,ZNF215,MLC1,PGAP1,DOK5,SPIRE1,FHOD3,EFEMP1,NUMBL,GALNT1,ZBTB38,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,FRAS1,PDE10A,HS3ST5,GAN,LRP6,ADCY6,SLCO4C1,FAR2,NIPAL2,FBXL2,PAK1,FGFR4,CHSY3,DPYSL5,UNC5C,BTNL9,MGAT4B,SPATA13,PPFIA4,WDR25,STRADB,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,TEX9,NEGR1,NAP1L5,GRIK4,CSF1,MFSD2A,SLC2A6,PLD1,SEMA3A,PANK3,TESC,MME,SIX2,ID1,CFH,DOCK1,XYLT1,RHPN2,RNF24,ZNF83,NTRK3,OR51B4,SLC7A2,KIF21B,SEZ6L2,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,CBLN1,PCLO,DDX60L,FAM131B,ZNF362,IDI1,TACC2,MYO3B,BCL6,EEPD1,MYH15,CLVS2,SCN2A,TMEM56,CTH,GLI1,INTU,TMEM67,EVL,CSN2,TMEM65,LRRC8B,TDRD3,THSD4,CHRNA6,VIM,PAGE5,FRK,JAM3,RANBP2,NRG3,PTPRJ,KCNG1,PTPRS,MAOA,HGF,SUSD4,ZNF701,C8orf48,CTNND2,CNTN1,HEY1,MAN2B2,TENM1,COL9A3,PCDH18,DYRK3,IL32,BMPR2,RUSC2,APBB1,GABRG2,PRDM8,RASD1,USP30,ARHGAP44,PPP2R3A,SLC35F1,FOXP2,TTC1,MAP1A,RASD2,GTF2F2,TSC22D1,PRICKLE2,TSPAN13,KIAA0408,SH3PXD2B,PCK2,SYK,SLC45A3,KIAA1211,ATP2B1,DLGAP1,MICAL2,LRRIQ1,FOXN3,NUAK2,PRICKLE1,FERMT2,PALLD,NPDC1,MKX,DKK1,EBF1,CD37,DOCK7,FAT4,FBN1,L3MBTL4,ZNF214,ZNF808,SH3BGRL2,DLG2,RPL4,TBC1D4,KIF1B,FILIP1,CACNA2D1,ZNF235,FAM171B,MYCBP2,PPP4R4,LANCL3,LGR4,SIDT1,ATP8A1,LDLR,GATA3,ENAH,PRKCA,AARS,SLC9A7,NCS1,STK24,TRPS1,SLC22A18,SERINC2,CHRDL1,KCNS3,GSTM3,ATRNL1,BEND4,PACSIN1,VWA5A,PLTP,GLDC,GDAP1,ERGIC1,EML6,NR6A1,WISP3,KLHL3,KLHL4,DNAJC6,LRMP,DEPTOR,SLC25A28,TNS1,ACVR2B,ZDHHC14,GPC6,GNAI1,AHRR,SFXN1,SH3RF1,NCKAP1L,PLK2,RASGRF2,BMP1,SERPINI1,DSEL,NRP1,TANC2,LZTS1,SPOCK3,EFNB2,SEMA6B,LRFN5,MRC2,INPPL1,FAM124A,CELSR1,PTPRD,ZHX3,TBC1D1,SCN8A,GABRB2,DHCR24,OPHN1,GTF2IRD1,ISYNA1,WDFY4,APBA1,DYNC1I1,PRRG4,MECOM,MTUS1,GBGT1,NAV1,SLC7A11,RALGPS2,CNTN4,NOVA2,PIK3AP1,C1QL4,RUNDC3B,SREBF1,PRKG1,CPXM2,GRIP1,MPDZ,SAMD13,COL9A2,RIMS2,BOD1,RNF152,IGSF3,EPB41L5,PTCH2,DISC1,TBC1D8B,SLC36A1,COL4A4,VLDLR,RAPGEF4,DCHS1,PACSIN3,KIAA1324L,PEX5L,CCDC85A,CDC42BPA,PLCB1,TMEM74,MMP15,DAGLA,XKR9,PLEKHH2,PKN3,ISM1,CECR2,THBS4,MPP2,SLFN5,SMYD3,AMPD1,ACSM3,FRMPD3,EPHA3,PLA2G4A,TCTN2,RASAL2,RNF144A,ST14,ZNF311,PLXNA2,OTX1,MSR1,CHUK,KCTD12,COL14A1,TBC1D30,ZFYVE9,CCDC120,NELL2,TMEM53,ZNF827,SPEG,ZNF438,ALDOC,SHF,NBEA,DAB2IP,NAP1L3,PDE4D,SERPINH1,GATM,GAB2,TRDMT1,VNN2,B3GALT1,PDK1,TMEM43,SFXN4,PANK1,PREX1,NLGN4X,SATB2,PRKCQ,PYGO1,TBC1D16,ATP10D,SNCA,HTR7,IKZF3,POPDC3,PRKCB,TDO2,CCNA1,MAP3K21,ZNF704,GRB10,BMPR1A,HS3ST3B1,CTTNBP2,NR3C2,COBL,STON2,PURG,HACE1,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,EPS8,PRSS35,HERC5,KIF5C,GABRR2,NDFIP2,PHLDA2,NEDD4,SOAT2,MGAT1,AFF2,GPR155,SGK3,RALGAPA2,SLC6A15,DYNC2H1,FIG4,ERRFI1,TBC1D9,SMAD6,GFI1,SEPT3,SPRY2,SMPDL3A,B4GALT6,TMC7,VAV3,SLC40A1,ARHGEF28,SYNPO2,CACNA1E,MPP1,PTPN13,ZDHHC15,UCHL3,GUCY1A2,SKAP1,GPR137C,ZIC1,GPLD1,OR2T33,TERT,PLXDC2,MCC,PGM2L1,SVIL,MYOM2,LARP1,ATP1A3,EXPH5,UGT8,KIF5A,UGDH,PTPN21,ACTL8,TNFAIP8L2,C20orf194,ABAT,ABHD4,DNER,RBM11,CACNB4,KREMEN1,SLCO3A1,HMCN1,CHST10,QPRT,RTN1,ARHGEF10L,SIPA1L2,LRRC6,GRHL1,AKAP7,ABI3BP,DLX6,ANKFN1,POF1B,CNNM2,TRPC1,PCOLCE2,PTPRE,MYRIP,IL1RAP,SLIT2,CYP1B1,LAMP3,TNK2,SKAP2,CAPN5,YAP1,ROR1,SGK2,RNF44,SERGEF,EML1,TMEM132B,TMEM150B,ITGBL1,NCAM2,FAM114A2,OXTR,PPARGC1A,APBA2,MAGI2,PCSK5,GPT2,GPR63,SV2B,MOCOS,FN1,OTOGL,SCART1,BVES,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,CHADL,GALNT13,CHSY1,FAM81A,SPINK5,PHGDH,CD7,PCDHB14,CA2,EEF2,FAM107B,LIMCH1,LRP3,CAND2,SNX7,NOS3,CDH26,GPR176,RAX,PCDH10,PODXL2,SLITRK2,SH2D2A,PARD3B,GSTM4,EDEM3,WWC1,DUSP9,LHPP,PRDM1,B4GALNT3,AMDHD1,PLAGL1,KIAA0355,FCHO2,NCR3LG1,FAT1,HK2,RAI14,DISP2,NKX2-8,OSBPL6,XKR4,CREB3L2,CXCR5,DMXL2,EML5,ZSWIM5,SORBS1,CELSR3,PLEKHA5,COL18A1,COBLL1,BCL6B,TDRKH,CANX,PIBF1,DOCK2,ZSCAN5A,SCIN,COL22A1,KCTD15,PDZD8,UNC13B,KAZN,PPFIBP1,REEP1,ZNF521,MAP7,ACVR2A,PROS1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,NTNG1,SEMA6C,DPP10,ANTXR2,PRAME,FER,PHLDB2,PTPRU,TTLL7,DOCK5,TPK1,BCL11A,ZNF569,ARMC4,MAGEA12,MSC,ZNF93,BACH2,RGS10,SOHLH2,DISP1,CYP2U1,RNF130,LIFR,MAST1,OR51B5,PRSS16,ARHGEF11,CLSTN2,IGF2BP2,COL4A5,NOTUM,CUEDC2,OVOL2,SEL1L3,SYDE2,KCNJ4,CHN2,PRKCD,STC2,EHD3,KIAA0319,TRIM3,AFAP1L2,IQGAP3,RRAS2,PNMA2,CARD6,MSX1,CRIM1,NR4A1,GRID1,ASAP3,MEI1,PRRG1,MARS,PHACTR2,ARHGAP32,C3orf70,ZFPM2,NAALADL2,LEPR,MAP1B,RERE,ADAMTS17,GPR37,DPY19L2,ICA1,EDA,MPP7,MAP2K6,THSD7B,SLC7A5,UACA,KIF21A,GEM,MMP16,NPHP1,SLC16A10,ABCG1,SNPH |
| 2.744e-15 | -33.53 | LEE_BMP2_TARGETS_UP | MSigDB lists | LEE_BMP2_TARGETS_UP | 685 | 134 | 17377 | 1707 |
EXPH5,TCP11L2,RECK,ATP8A1,FAM102B,NDRG2,ITPR2,ABHD4,F3,QPRT,TRPS1,EPCAM,RND2,PPM1E,FBXO32,KCNAB1,SLC16A2,TMEM86A,SERINC2,VWA5A,PLTP,CPE,MEIS2,PNRC1,WLS,CAPN5,GDPD1,DEPTOR,NFIA,MSRB3,SESN1,ARHGEF26,ERN1,AHNAK2,BMP1,OXTR,CRYL1,RRAGD,SV2B,FAM124A,ZNF395,RHOBTB1,PTPRD,STXBP6,YPEL2,CYP4V2,SATB1,HSPA12B,DDIT4,MECOM,EFEMP1,CA2,BCHE,BACE2,ADCY6,CPXM2,JAM2,CEBPD,IGSF3,IL17RD,PARD3B,COL4A4,VLDLR,DCHS1,C1R,PELI2,MATN2,RAB31,PLD1,TFCP2L1,NBL1,ST14,COL18A1,SLC7A2,RADIL,DDR1,PPP1R9A,RNF150,ZNF521,SCRN1,SNAI2,COL6A2,SLC39A8,GSTO1,ATP1B1,RARRES2,TTC28,DSP,GABARAPL1,ENTPD1,MSC,WFS1,GBP1,KCNG1,PAM,HPGD,RNF130,DBP,KCTD1,TMEM132C,SLC6A9,PLSCR4,IGFBP6,GRB14,ESRP1,EPS8,BLVRB,RASD1,FUT9,AFF2,DSG2,GHR,RASD2,TSC22D1,AFAP1L2,KLF9,PCK2,SMPDL3A,TRPM4,SLC40A1,VAV3,OPLAH,MSX1,SYNPO2,RAB6B,PHACTR2,NPDC1,LEPR,RERE,HK1,LRRK1,TBC1D4,CRISPLD1,STOM |
| 3.272e-15 | -33.35 | plasma membrane part | cellular component | GO:0044459 | 2777 | 379 | 18223 | 1724 |
ACVR1,LGR4,GRIK2,LDLR,CADM2,PRKCA,SNX9,ABHD6,NCS1,NOS1AP,PCDH7,TGFBR3,SLC22A18,SLC16A2,RAB26,KCNS3,PACSIN1,TSHR,CPE,ACVR1C,WLS,GJB2,TGFA,LRRK2,LRMP,ABCC2,ACVR2B,KCND3,GPC6,GNAI1,SLC7A1,ENPP1,NCKAP1L,ATP7B,ADRB1,SPRY4,TPM1,LZTS1,EFNB2,SEMA6B,SCN5A,GNG12,MRC2,CELSR1,PTPRD,GABRB2,SCN8A,ITGA6,TJP1,SLC1A3,TNFRSF10C,GPSM2,BBS9,GAS1,SLC7A11,CACNB2,FLRT3,OPN3,GRIP1,TSPAN12,CADPS2,LMAN2,MPDZ,SLC16A9,NCAM1,STXBP1,TSPAN9,JAM2,GFRA1,RIMS2,LRP12,CHRM3,GPR161,EPB41L5,DISC1,KCNQ3,MYO10,CALCRL,HIP1,SNAP25,OR11H4,CPEB1,DAGLA,MMP15,MPP2,CDH17,CDH2,TRPC3,EPHA3,DNM3,AMOTL1,TCTN2,RASAL2,ST14,GPR65,MSR1,PLXNA2,ADD2,KCTD12,CHUK,IL13RA1,NRXN1,LCP2,DDR1,GPR15,EPB41L3,PLPP1,TLR3,CHRNA5,COL25A1,CNKSR3,DAB2IP,PDE4D,RAB27B,PERP,KCNB2,DOCK8,SCN3A,FZD4,KCNH5,SHANK2,ADCY1,NLGN4X,PRKCQ,ATP1B1,DSP,FGFR1,PATJ,GABARAPL1,DCBLD2,GJC1,HTR7,SLC39A14,ENTPD1,CXCL10,GYPC,PEMT,ASIC1,MAP3K21,HPGD,TNFSF15,HS3ST3B1,BMPR1A,MYO1D,FARP1,EDA2R,ROBO2,CD276,FZD8,BACE1,EPS8,ARL2,PSD3,GABRR2,SLC12A6,P2RY1,PKN1,EPHB1,RGS7,SLC35G2,KCNC4,TSPAN17,NEDD4,NEO1,LRRC55,GHR,PRKG2,SLC6A15,NPTXR,MYO6,ERRFI1,SPRY2,FES,ULBP1,TRPM4,SLC40A1,LZTS3,CACNA1E,MPP1,RAPGEF2,RASA3,RACK1,SNTB1,SKAP1,HEG1,PTPRC,FGR,PCDHB7,PLPPR2,CLDN12,GNAO1,SLCO5A1,SVIL,GRIN2D,ATP2B4,OCLN,ATP1A3,SLC43A1,CACNG3,FGF13,LILRB1,SLC2A13,CACNB4,SLCO3A1,HMCN1,F3,EPCAM,KCNAB1,TM9SF2,HPS1,MARVELD2,ITGB3,TRPC1,LIN7A,CNNM2,SLC2A12,EPHB6,CTTN,TLR4,IL1RAP,PDGFRB,ITGB7,TNK2,SLC3A2,CD55,ATF4,KCNIP3,ABCC4,CEMIP2,ANK2,PLPP2,PLEKHA1,ROR1,TMEM150B,KCNMB4,TNFRSF1A,AHNAK2,OXTR,ADGRA3,TNFSF4,KCNV1,TYRO3,FN1,LGALS3,SCART1,BVES,MLC1,SPIRE1,PCDHB14,CA2,IGF1R,SEMA4F,ADCY6,LRP6,SLCO4C1,NOS3,FGFR4,PAK1,IL17RD,GPR176,CDH26,PCDH10,PODXL2,BTNL9,PARD3B,HOMER2,EFNA3,SPATA13,WWC1,CATSPERE,STEAP1,GPR19,BAIAP2,KCNK15,GRIK4,RIPOR2,FCHO2,MFSD2A,FAT1,SLC2A6,PTPRN2,PLD1,TESC,MME,CXCR5,SORBS1,IL15,AKAP5,NTRK3,SLC7A2,PRR7,CBLN1,SEMA6A,CTNNA2,CD53,SLC22A17,UNC13B,ADGRL1,MAP7,ACVR2A,STEAP3,SCN2A,MET,HSPA2,NTNG1,SEMA6C,DPP10,ANTXR2,FER,TMEM67,PTPRU,PTPN6,SLC39A8,CHRNA6,AMIGO1,CD40,FRK,CAMK2N1,NRG3,PTPRJ,PTK7,TMPRSS9,KCNG1,ITGA2,PTPRS,DISP1,LIFR,TENM1,PCDH18,TNIK,LPAR2,SLC6A9,BMPR2,TSPAN15,LRP4,APBB1,CLSTN2,SELL,GABRG2,ARHGAP44,FSD1,KCNJ4,SCN1B,EHD3,DSG2,KCNMB3,TSPAN13,IQGAP3,TNFRSF11A,SYK,ATP2B1,DLGAP1,CYTH3,LITAF,GRID1,PRRG1,FERMT2,ARHGAP32,TLR6,LEPR,HOMER3,GPR37,CD37,EDA,MPP7,CTSV,SLC7A5,SLC18B1,DLG2,SLC22A15,GEM,SLC1A5,IL9R,MMP16,CACNA2D1,SLC16A10,ABCG1,SNPH,STOM |
| 3.530e-15 | -33.28 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 1136 | 193 | 17385 | 1698 |
ARHGAP26,CGN,PPP4R4,TTC39B,CNTNAP3,SYT12,DNAJC3,ENAH,FAM13A,CA8,DACH2,HMCN1,FSTL5,SLC9A7,CEP85L,NOS1AP,PCDH7,AKAP7,SLC16A2,PPFIA2,ANKFN1,CHRDL1,POF1B,ATRNL1,LIN7A,TLN2,FANK1,GLDC,ABCC4,DCDC1,COL4A3,KLHL3,CAP2,ANK2,DSTN,ZDHHC14,GPC6,GNAI1,TRIM9,TMEM132B,NCAM2,CCBE1,TECPR2,UNC5B,APBA2,MAGI2,SPOCK3,BCL11B,CELSR1,RHOBTB1,OPHN1,MRPL22,WDFY4,APBA1,TNFRSF19,MLC1,FHOD3,MTUS1,KIAA1958,IGF1R,KIAA1671,FAM189A1,FRAS1,PRKG1,TOX,FAR2,MOXD1,FAM155A,TSPAN9,PRR16,GFRA1,HMGCR,GPR176,BDNF,UNC5C,KCNQ3,ARID5B,RAPGEF4,RYR2,OBSCN,SLITRK5,TTYH2,ST6GALNAC3,SDK1,PLCB1,KHDRBS2,NEGR1,CSAG1,PTPRN2,SEMA3A,CDH2,SMYD3,ANKRD20A5P,DOCK9,EPHA3,EML5,TCTN2,DOCK1,CCDC110,ARHGAP22,MYO1B,HECW2,PCLO,EPB41L3,COL22A1,UNC13B,TACC2,KAZN,EEPD1,BCL6,NBEA,RTKN2,FHIT,GULP1,PROS1,CLVS2,DNAH5,TMEM120B,MYT1,DZANK1,ANTXR2,FER,THSD4,SHANK2,FGF12,WNT11,ASPH,JAM3,TPK1,HTR7,NRG3,LMLN,KPNA3,PLEKHG1,MAOA,TTC39A,CTTNBP2,COBL,ANO10,MXI1,NECAB2,BMPR2,CMTM8,C1orf226,CCNJL,CLSTN2,SELL,PSD3,NKAIN2,ARL2,FAM117B,RGS7,NDFIP2,FAM174B,SEL1L3,BMP6,ARHGAP44,SLC35F1,NKX6-1,GHR,DSG2,GTF2F2,DYNC2H1,TBC1D9,TMC7,DLGAP1,SYNPO2,CACNA1E,ESRRG,RAPGEF2,ZDHHC15,GRID1,RASA3,ATP11A,ARHGAP32,GUCY1A2,ZFPM2,PALLD,SKAP1,NAALADL2,MGMT,TRIB3,DOCK7,FAT4,TERT,MPP7,L3MBTL4,THSD7B,MYOM2,DLG2,DCBLD1,FILIP1,CACNA2D1 |
| 3.537e-15 | -33.28 | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | 519 | 110 | 17377 | 1707 |
CREB3L2,MPZL3,FAM171B,CGN,ACVR1,DNM3,ACSL1,FLVCR2,FGF13,ATP8A1,GALNT12,PSTPIP2,MYO1B,PPFIBP2,COBLL1,ENAH,IL13RA1,FAM198B,KIAA1217,FAM13A,DDR1,DENND3,TBC1D30,CDS1,ZNF827,UNC13B,CDC14B,TACC2,BCL6,ACVR2A,PDE4D,PACSIN1,TLN2,RAB27B,TBC1D8,PRAME,CD55,MARK1,FZD4,WLS,FAM84A,SHANK2,NFIA,PREX1,NLGN4X,MFSD6,DOCK5,ASPH,CRYBG3,CENPV,PTPRJ,KLF12,ZNF697,GPR160,INPP4B,ZNF704,FAM149A,LATS2,CYP2J2,RASL11B,RASD1,INPP1,BEX2,MTUS1,RAB11FIP5,GALNT1,SYCP2,PRTFDC1,FUT9,GATA2,SCN1B,EHD3,GAN,PRICKLE2,CADPS2,LIMCH1,NCEH1,ATP2B1,IGSF3,B4GALT6,RIN2,MID2,ARAP2,SLC37A1,TBC1D8B,RAPGEF2,PTPN13,LITAF,TCEA3,SPATA13,WWC1,FERMT2,PDE8A,C3orf70,BAIAP2,GALNT3,EBF1,BEX4,TRIB3,TMCO3,ICA1,RND3,THBS4,SH3BP4,KIAA0513,GRIN2D,SLC22A15,PLD1,PKIA,STOM |
| 4.085e-15 | -33.13 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | 446 | 99 | 17377 | 1707 |
EPHA3,PLA2G4A,TFCP2L1,TRIM2,ID1,LANCL3,VAMP8,PPFIBP2,LMCD1,PLXNA2,GATA3,COBLL1,NRN1,DNER,KBTBD11,CYP26A1,PLS3,EPCAM,MYO3B,SLC2A12,BEND4,PROS1,TMEM37,PCOLCE2,VWA5A,HSPA2,CYP1B1,C3orf67,SUSD3,ERGIC1,ABCC4,SKAP2,SLC39A8,CAPN5,GDPD1,FGF12,GSTO1,ZDHHC14,ARHGEF26,BATF3,GSN,KCNMB4,GPRC5B,CCBE1,BDH2,HPGD,MAPK13,FAM149A,HS3ST3B1,HOXB9,GNG12,COL9A3,IGFBP6,RASL11B,COL4A5,RASD1,GAS6,BBS9,TPD52L1,SPINK5,HOPX,EFEMP1,RALGPS2,FUT9,FAM189A1,BHLHA15,GPR155,STC2,SGK1,TSPAN12,TSPAN13,KLF9,SLCO4C1,ERRFI1,RRAS2,FAM155A,CEBPD,TMC7,SLC40A1,USP2,PTPN13,CYTH3,VLDLR,TMTC4,CALCRL,MAFB,GPLD1,MKX,ID3,MPP7,MFSD2A,TMEM117,TUFT1,LRRK1,SLC1A5,TESC,PTGES,FOXA1,ACSM3 |
| 4.853e-15 | -32.96 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | 654 | 129 | 17377 | 1707 |
ARHGAP26,CGN,LGR4,DNAJC3,PPFIBP2,SLC2A13,PRKCA,FAM13A,IKZF2,STK24,FBXO32,LRRC6,RAB26,KCNS3,SLC2A12,PTPRE,PRKACB,TBC1D8,CYP1B1,CD55,ACVR1C,FAM84A,CAPN5,MFSD6,CRYBG3,AK1,INSIG1,SH3RF1,ENTPD7,ATP7B,ADRB1,TC2N,SLK,RIMKLA,DHCR24,SLC25A27,TNFRSF19,MTUS1,GALNT1,FRY,KIAA1671,MSMO1,PIK3AP1,BACE2,FAM107B,LIMCH1,SLC16A9,NCEH1,SNX7,HMGCR,PAK1,QSOX1,BDNF,CDH26,SLC37A1,SLC27A2,TCEA3,C4orf19,STEAP1,TBC1D2,PLEKHH2,PELI2,SQLE,CLMN,PTPRN2,PLD1,SIX2,DIRC2,DOCK9,DMXL2,CREB3L2,NBL1,RNF144A,ST14,GALNT6,GALNT12,IL13RA1,CHUK,CDS1,IDI1,TACC2,CDC14B,STARD4,EEPD1,ACVR2A,IGFBP3,RNF145,LRRC8B,PFKFB2,ATP1B1,AMIGO1,ASPH,TTLL7,CENPV,PTPRJ,POPDC3,RBPMS2,TNFSF15,CTTNBP2,MAPK10,HEY1,C1QTNF3,CLGN,FZD8,IGF2BP2,INPP1,ARHGAP44,RGS17,CHN2,TSC22D1,MARCH3,PCSK6,B4GALT6,RIN2,PPP1R3D,CRIM1,RAB6B,PTPN13,C3orf70,SNTB1,DPY19L2,GALNT3,CEBPB,MFSD9,CLDN12,SRD5A3,SH3BGRL2,PAX9,DCBLD1 |
| 5.248e-15 | -32.88 | follicular_lymphoma | COSMIC cancer mutations | follicular_lymphoma | 1243 | 206 | 17385 | 1698 |
FLVCR2,SIDT1,ATP8A1,UGDH,MCOLN3,NPM1,CADM2,ITPR2,PRKCA,IKZF2,DNER,HMCN1,FSTL5,NOS1AP,PCDH7,TGFBR3,KCNN2,PPFIA2,ANKFN1,CHRDL1,COL19A1,ATRNL1,JAKMIP2,MYRIP,ETV1,SLIT2,NEB,RASGRP1,TBC1D8,PGBD5,EML6,CAP2,KLHL4,CAPN5,MEF2B,INTS6,GPC6,TMEM132B,MAP2,NCAM2,TPM1,PPARGC1A,MAGI2,HS6ST3,KCNV1,MOCOS,EHHADH,SEC24D,UBASH3B,GABRB2,OPHN1,SETBP1,GALNT13,FAM81A,PRRG4,FHOD3,MTUS1,EFEMP1,IGF1R,FRY,SLC30A4,CNTN4,PIK3AP1,FRAS1,PDE10A,EBF4,PRKG1,GAN,CPXM2,MPDZ,TSPAN12,NCAM1,FAM155A,AGL,PRR16,LRP12,RIMS2,FADS1,PCDH10,UNC5C,PNP,COL4A4,GPSM1,TCEA3,RYR2,ST6GALNAC3,CCDC85A,SDK1,B4GALNT3,KHDRBS2,NEGR1,TBC1D2,CACHD1,GRIK4,TEX15,SH3GL2,ADAMTS3,ISM1,PELI2,CECR2,C1orf21,MATN2,RAB31,TMEM117,CLMN,LAPTM4B,PTPRN2,OSBPL6,MME,DOCK9,CXCR5,ZSWIM5,DNM3,DOCK1,MSR1,BCL6B,IL13RA1,LCP2,RADIL,PIBF1,DOCK2,PCLO,TBC1D19,ZNF827,SPEG,PDZD8,KMO,ZNF521,FAM155B,POU2F2,DNAH5,SNX10,KCNB2,SCN3A,DPP10,SHANK2,ADCY1,NLGN4X,SATB2,RAB38,CD40,TTC28,DOCK5,METAP1D,SMAD3,ENTPD1,ARHGAP21,RANBP2,NRG3,PDLIM3,PEMT,INPP4B,PTPRS,GRB10,RNF130,HS3ST3B1,NR3C2,STON2,MID1,COBL,CTNND2,TNIK,CCDC148,WDR17,ROBO2,ATP9A,C1orf226,HERC5,PSD3,NKAIN2,RGS7,NEDD4,CHN2,GPR155,AFF2,DSG2,GTF2F2,KIAA0319,FIG4,SYK,TNFRSF11A,KIAA1211,MED12L,DUSP1,BCL7A,AGPAT4,PTPN13,ATP11A,ZFPM2,GPR137C,NAALADL2,SMPDL3B,EBF1,ID3,DDAH1,DOCK7,PLOD2,MPP7,PLXDC2,XBP1,UACA,ZNF808,TBC1D4,MMP16,ATP2B4,CACNA2D1 |
| 1.170e-14 | -32.08 | KRAS.KIDNEY_UP.V1_UP | MSigDB lists | KRAS.KIDNEY_UP.V1_UP | 135 | 46 | 17377 | 1707 |
SV2B,DNM3,PLSCR4,TRIM2,SORBS1,GRIK2,KIF5C,NRN1,GABRR2,SLC1A3,NRXN1,SATB1,DYNC1I1,HPCAL4,RTN1,TUBB4A,EPB41L3,CA2,SCN1B,MAP7,SLC6A15,LIMCH1,SCN2A,CPE,ETV1,GATM,GLDC,PNMA2,GPM6A,ESRRG,ANK2,RAPGEF4,ADCY1,MAFB,SNAP25,PLCB1,GPR19,GPR37,TRIM9,GPRC5B,ITGBL1,PELI2,CAB39L,SERPINI1,MEF2C,HEY1 |
| 1.543e-14 | -31.80 | lymph_node | COSMIC cancer mutations | lymph_node | 1755 | 267 | 17385 | 1698 |
FAM171B,CGN,ACVR1,FLVCR2,GRIK2,ATP8A1,GATA3,NPM1,STAT5B,PRKCA,KIAA1217,DACH2,STK24,PCDH7,TRPS1,PPFIA2,ATRNL1,TMEM37,RCAN3,GLDC,MEIS2,EML6,SMAD9,DCC,WLS,TGFA,KLHL4,MEF2B,FEZ1,ACVR2B,GPC6,ARHGEF26,PLK2,SEMA3C,MAPK13,ERCC5,DSEL,SPOCK3,MEF2C,LATS2,MRC2,CELSR1,PTPRD,ITGA6,SLC1A3,PRRG4,SYCP2,FRY,ADCK1,FAM189A1,MYC,PRELID2,PRKG1,MPDZ,TOX,ST8SIA1,FAM155A,STXBP1,LRP12,RIMS2,CHRM3,FADS1,PNP,SPATA6,DCHS1,RYR2,TTC30A,HIP1,SHISA2,CDC42BPA,PLCB1,MBNL2,DAGLA,ADAMTS3,ISM1,PELI2,CLMN,ACSM3,TFCP2L1,EPHA3,ZNF311,CHUK,GRK6,DDR1,CDS1,SPEG,COL25A1,ALDH1L1,FAM133A,SNX10,PDK1,SATB2,ATF3,ATP1B1,FGFR1,IKZF3,IQCH,PDLIM3,PRKCB,WFS1,WWTR1,ZNF704,BMPR1A,PLD5,LRRC27,NR3C2,STON2,HACE1,CCDC148,ROBO2,ATP9A,FZD8,PLAG1,EPS8,RGS7,NEO1,AFF2,SMAD6,FES,MED12L,B4GALT6,BCL7A,LCA5,ARAP2,RAB6B,CACNA1E,PTPN13,AK4,RASA3,GPR137C,ID3,TRIB3,FGR,RPL12,PLOD2,AKT3,XBP1,SVIL,MYOM2,HK1,DDIT3,TLL2,EXPH5,MVK,UGDH,LILRB1,ITPR2,IKZF2,SLCO3A1,HMCN1,KREMEN1,CEP85L,FSTL5,FKBP9,RPS6KA2,ABI3BP,ANKFN1,COL19A1,JAKMIP2,CTTN,FANK1,MYRIP,PTPRE,SLIT2,IL1RAP,PDGFRB,PRKACB,TNK2,GPM6A,ANK2,TTC22,SESN1,CRYBG3,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,TNFRSF1A,PIK3C2B,MAGI2,FRMD5,PCSK5,CHMP4C,KCNV1,LAMC3,FHOD3,KIAA1958,GALNT1,PRTFDC1,IGF1R,NCEH1,CHSY3,FGFR4,PAK1,PARD3B,DUSP9,SDK1,PRDM1,B4GALNT3,MAPKAPK2,HK2,PTPRN2,PANK3,DMXL2,CXCR5,NEK10,CFH,DOCK1,IL15,COL18A1,TDRKH,NTRK3,DENND3,PCLO,DOCK2,PPP1R9A,TBC1D19,RPS6KL1,BCL6,ZNF521,MYO3B,ACVR2A,FHIT,GULP1,MET,SEMA6C,DPP10,DOCK5,FRK,BCL11A,CAMK2N1,NRG3,PTK7,SOHLH2,SUSD4,LIFR,CTNND2,MAST1,OR51B5,TNIK,MCTP2,CLSTN2,MCU,FOXP2,TSC22D1,SGK1,PRICKLE2,TNFRSF11A,SYK,KIAA1211,RAB3B,CRIM1,OGDHL,ZFPM2,PALLD,NAALADL2,RERE,EBF1,FAT4,L3MBTL4,ZNF214,MAP2K6,SH3BGRL2,KIF21A,TBC1D4,CACNA2D1 |
| 1.972e-14 | -31.56 | cellular component morphogenesis | biological process | GO:0032989 | 777 | 142 | 17256 | 1658 |
UGT8,KIF5A,GATA3,ENAH,PRKCA,RAC3,STK24,ITGB3,POF1B,CTTN,PACSIN1,ETV1,SLIT2,PDGFRB,NKX2-1,ATL1,ITGB7,GPM6A,DCC,ANK2,CAP2,LRRK2,YAP1,FEZ1,ARHGEF26,TSKU,NCKAP1L,MAP2,AHNAK2,SEMA3C,TMOD2,UNC5B,NRP1,TPM1,MEF2C,BCL11B,EFNB2,TYRO3,LRFN5,FN1,BVES,OPHN1,LAMC3,SLC1A3,FOXG1,DOK5,FHOD3,CHN1,NUMBL,CNTN4,FRY,SEMA4F,PDZD7,FLRT3,NCAM1,STXBP1,GFRA1,ZNF385A,EPB41L5,PAK1,DPYSL5,CDH26,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,OBSCN,STRADB,BAIAP2,SH3GL2,WDR19,MATN2,NKX2-8,CDH2,SEMA3A,SHTN1,TFCP2L1,NBL1,ID1,ST14,CELSR3,RBFOX2,PLXNA2,COL18A1,NRXN1,RADIL,DDR1,SEMA6A,CTNNA2,EPB41L3,COL25A1,BCL6,DAB2IP,MET,ZNF365,NTNG1,SEMA6C,GAB2,FER,MYLK3,EVL,FZD4,PTPN6,SHANK2,ADCY1,PRKCQ,AMIGO1,ATOH1,IRS2,LAMB1,HGF,GRB10,COBL,CTNND2,TENM1,TNIK,FARP1,ROBO2,LRP4,APBB1,KIF5C,EPHB1,NEO1,LRRC55,LRRN1,MAP1A,SCN1B,SGK1,FIG4,PDLIM7,MSX1,FERMT2,PALLD,PEAK1,RERE,MAP1B,HEG1,DKK1,DOCK7,MYOM2 |
| 2.726e-14 | -31.23 | prostate-carcinoma-adenocarcinoma | COSMIC cancer mutations | prostate-carcinoma-adenocarcinoma | 12749 | 1372 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,GRK6,TLR3,ALDH1L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,SLC39A14,ARHGAP21,PDLIM3,WFS1,LAMB1,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,PCBP4,GHR,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RUFY4,CPNE2,TM9SF2,CPVL,SEC16B,AADAT,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,PGBD5,DBN1,MARK1,KCNIP3,ATF4,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,DPYSL5,BTNL9,GPSM1,STRADB,SLITRK5,OBSCN,SDK1,KHDRBS2,NEGR1,TBC1D2,GRIK4,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,IGFBP3,HRASLS,INTU,CSN2,TMEM65,LRRC8B,PRDM13,ACO1,RNF125,CHRNA6,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,HEY1,TENM1,SLC6A9,BMPR2,KLHL13,MCTP2,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,TMEM74,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,TMEM170B,COL14A1,ZFYVE9,TIAM2,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,GATM,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,IKZF3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,STON2,PURG,MID1,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,TERT,PLXDC2,MCC,SVIL,CERS1,LARP1,ACSL1,UGT8,PTPN21,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,TRPC1,CNNM2,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,TMEM47,COTL1,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,CD40,BATF3,BCL11A,ZNF569,ARMC4,MAGEA12,ZNF93,KPNA3,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,TSPAN15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,SYDE2,MCU,RAB11FIP5,FSD1,KCNJ4,PRKCD,STC2,ACTA2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,EDA,MFSD9,RND3,ACER2,UACA,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,CA8,NOS1AP,EYA4,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,DNAH6,FAAH2,PPFIA2,TSHR,RWDD2A,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,F12,MFSD6,CA13,ZNF266,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,BNIP1,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,PLS1,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,FAM131C,GALNT6,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,TXNRD3,CDS1,EPB41L3,CHRNA5,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,P4HA1,RCN3,ALG11,TNFSF15,PLD5,KLHL31,FARP1,TMEM132C,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,KCNC4,COL27A1,NEO1,MYO6,NPTXR,FES,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,PLPPR2,GNAO1,OSBPL5,SLCO5A1,HK1,DOCK6,DCBLD1,BTRC,FOXA1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,ETV1,NEB,ITGB7,SLC3A2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,ZCCHC24,UBASH3B,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,KIAA0895,IGF1R,SEMA4F,ABCA5,BCHE,PDE10A,SAMD11,SLCO4C1,FBXL2,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,WDR25,PDE8A,TEX9,MAPKAPK2,ATPAF2,MFSD2A,HEYL,PANK3,TESC,MME,SIX2,CFH,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,SEZ6L2,PCLO,CBLN1,CYP26A1,TBC1D19,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,THSD4,FGF12,GSTO1,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,KCNG1,ABI3,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,GRB14,RUSC2,APBB1,BLVRB,GABRG2,HBE1,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,PRICKLE2,KLF9,SH3PXD2B,PCK2,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,FNDC3A,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,SLC22A15,PAX9,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,ATRNL1,BEND4,MAGEA6,VWA5A,PACSIN1,PLTP,TBC1D8,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,PMEPA1,ISM1,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,ZNF827,TMEM53,NELL2,STARD4,NBEA,DAB2IP,MARCKS,ATP6AP1L,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,DENND5B,ANO10,WASF3,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,ATP1A3,EXPH5,MPZL3,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,QPRT,RTN1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,SLIT2,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,RIMKLA,YPEL2,CYP4V2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,FAM107B,EBF4,NCEH1,NOS3,GPR176,SH2D2A,PARD3B,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,IL15,CELSR3,PLEKHA5,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,GULP1,MDH1B,WWC2,MET,ZNF460,HSPA2,DPP10,PHLDB2,FER,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,LIFR,PSPH,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,IQGAP3,RRAS2,TNFRSF11A,RAB3B,ESRRG,CYTH3,GRID1,OGDHL,MEI1,PRRG1,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,MAP3K20,MMP16,SLC16A10,STOM,SNPH |
| 3.646e-14 | -30.94 | GO_CELL_JUNCTION | MSigDB lists | GO_CELL_JUNCTION | 1109 | 187 | 17377 | 1707 |
DOC2A,ARHGAP26,CGN,FGF13,GRIK2,SYT12,NPM1,ENAH,NRN1,CTBP2,CADM2,HMCN1,NCS1,EPCAM,MARVELD2,ITGB3,POF1B,LIN7A,CTTN,PACSIN1,TLN2,PDGFRB,DBN1,TNK2,ANK2,GJB2,LRRK2,CAPN5,NFIA,TNS1,ABCC2,TMEM47,TRIM9,GSN,ATP7B,ARHGAP28,OXTR,SPRY4,NRP1,MAGI2,LZTS1,LPP,EFNB2,SCN5A,SV2B,MRC2,BVES,GABRB2,ITGA6,OPHN1,SORBS3,TJP1,MLC1,RPL13A,FLRT3,RPS11,SCARF2,GRIP1,CADPS2,MPDZ,JAM2,TSPAN9,RIMS2,CHRM3,FGFR4,EPB41L5,PAK1,DISC1,UNC5C,PARD3B,HOMER2,FHL2,RABAC1,SDK1,CDC42BPA,SNAP25,C4orf19,STEAP1,CPEB1,TBC1D2,GRIK4,FAT1,PTPRN2,CDH2,CSRP2,MME,DMXL2,SORBS1,AMOTL1,SCAMP1,ARHGAP22,PKP2,KCTD12,LCP2,NRXN1,PRR7,PCLO,PPP1R9A,CBLN1,CTNNA2,CD53,EPB41L3,CHRNA5,UNC13B,DACT1,KAZN,PPFIBP1,MARCKS,SCN2A,SYNGR3,PERP,RPS13,FZD1,FER,PHLDB2,EVL,PTPRU,TMEM65,FZD4,PTPN6,TES,SHANK2,CHRNA6,NLGN4X,VIM,ATP1B1,DSP,JAM3,MAGI3,GJC1,SNCA,CAMK2N1,ARHGAP21,PTPRJ,LMLN,PTK7,ITGA2,STON2,CTNND2,FARP1,EPS8,GABRG2,PSD3,GABRR2,ARHGAP44,RGS17,KCNJ4,SCN1B,EHD3,DSG2,PRKCD,SH3PXD2B,IQGAP3,RRAS2,SEPT3,FES,DLGAP1,PDLIM7,SYNPO2,PXN,RAPGEF2,ASAP3,GRID1,FERMT2,ARHGAP32,SNTB1,PALLD,SKAP1,PEAK1,MAP1B,HEG1,HOMER3,PTPRC,ICA1,DOCK7,RPL12,MYADM,RND3,MPP7,CLDN12,SVIL,GRIN2D,DLG2,RPL4,NPHP1,OCLN,SNPH |
| 4.227e-14 | -30.79 | GO_CELLULAR_COMPONENT_MORPHOGENESIS | MSigDB lists | GO_CELLULAR_COMPONENT_MORPHOGENESIS | 857 | 154 | 17377 | 1707 |
UGT8,KIF5A,GATA3,ENAH,TGFBR3,EOMES,LRRC6,ITGB3,CTTN,PACSIN1,ETV1,SLIT2,PDGFRB,NKX2-1,ATL1,ITGB7,GPM6A,ABCC4,DCC,CAP2,ANK2,LRRK2,YAP1,FEZ1,ARHGEF26,TSKU,GSN,MAP2,SEMA3C,TMOD2,UNC5B,NRP1,TPM1,MEF2C,TYRO3,BCL11B,EFNB2,LATS2,LRFN5,FN1,BVES,OPHN1,LAMC3,SLC1A3,BBS9,TTC30B,FHOD3,CHN1,NUMBL,ABLIM1,CNTN4,SEMA4F,FRY,PDZD7,FLRT3,LRP6,NCAM1,STXBP1,ZNF385A,DPYSL5,PAK1,EPB41L5,BDNF,DISC1,UNC5C,SLITRK2,SPATA6,VLDLR,EFNA3,TTC30A,SLITRK5,OBSCN,STRADB,BAIAP2,THBS4,HEYL,WDR19,MATN2,DYNC2LI1,FNBP1L,SEMA3A,NKX2-8,SIX2,TFCP2L1,NBL1,ID1,TCTN2,CELSR3,ST14,RBFOX2,PLXNA2,COL18A1,NRXN1,RADIL,PIBF1,SEMA6A,CTNNA2,EPB41L3,COL25A1,BCL6,DAB2IP,MET,DNAH5,SNX10,NTNG1,SNAI2,SEMA6C,INTU,FER,TMEM67,MYLK3,EVL,FZD4,PTPN6,ADCY1,WNT11,PRKCQ,ATOH1,AMIGO1,ARMC4,IFT81,WWTR1,LAMB1,HGF,LIFR,COBL,CTNND2,HEY1,FARP1,ROBO2,LRP4,APBB1,KIF5C,EPHB1,NEO1,LRRC55,LRRN1,SCN1B,EHD3,SGK1,FIG4,DYNC2H1,B9D1,MSX1,FERMT2,PALLD,PEAK1,MAP1B,HEG1,DKK1,RERE,DOCK7,TMEM237,BMP4 |
| 4.468e-14 | -30.74 | ONDER_CDH1_TARGETS_2_DN | MSigDB lists | ONDER_CDH1_TARGETS_2_DN | 442 | 96 | 17377 | 1707 |
EXPH5,PLA2G4A,TFCP2L1,LGR4,ST14,RHOD,GALNT6,PSTPIP2,MYO1B,MCOLN3,COBLL1,DDR1,NUP62CL,PCDH7,F3,CDS1,EPCAM,KAZN,MAP7,SNX10,PTPRE,RAPGEF5,IL1RAP,PERP,SLC3A2,CD55,MARK1,WISP3,SLC39A8,CYB5R2,TGFA,FEZ1,RAB38,DSP,SNCA,ISG20,CAMK2N1,TCF7L1,POPDC3,HPSE,PLK2,CCNA1,KCNG1,ITGA2,INPP4B,MAOA,KLF5,SEMA3C,MAPK13,CNTN1,SERINC5,MYO1D,LPAR2,CELSR1,GRB14,ITGA6,ESRP1,ST6GAL1,BIK,MCTP2,OVOL2,SLC1A3,HERC6,SEL1L3,TPD52L1,PRRG4,FHOD3,MECOM,MTUS1,ABLIM1,CA2,BACE2,FLRT3,DSG2,TSPAN13,SLC6A15,MAST4,SYK,RIMS2,LRP12,IGSF3,ARAP2,SYBU,WWC1,GALNT14,HOXA1,STEAP1,SMPDL3B,GALNT3,SLC7A5,SEMA3A,TBC1D4,PTGES,SFN,OCLN,ATP2B4 |
| 5.347e-14 | -30.56 | neuron part | cellular component | GO:0097458 | 1528 | 232 | 18223 | 1724 |
DOC2A,CACNG3,PDE1B,FGF13,GRIK2,PRSS12,SYT12,KIF5A,LDLR,VAMP8,ASS1,NDRG2,CADM2,ABAT,DNER,RAC3,NCS1,TUBB4A,BAG3,KCNAB1,KCNN2,PPFIA2,RAB26,LIN7A,CTTN,EPHB6,PACSIN1,MYRIP,CPE,DBN1,ATL1,GPM6A,KCNIP3,ATF4,DCC,WLS,CAP2,ANK2,LRRK2,DNAJC6,FEZ1,PRKAR2B,EFHC1,KCND3,ROR1,TRIM9,MAP2,NCAM2,PLK2,MAP9,SERPINI1,TMOD2,INPP5F,NRP1,PPARGC1A,APBA2,MAGI2,LZTS1,BCL11B,PRKAA2,SV2B,GABRB2,SCN8A,OPHN1,SLC25A27,SLC1A3,APBA1,PFN2,NAV1,CA2,CNTN4,IGF1R,PDZD7,PDE10A,FLRT3,OPN3,LRP6,GRIP1,MPDZ,CADPS2,BNIP3,MORN4,STXBP1,CHRM3,ZNF385A,RIMS2,PAK1,DPYSL5,UNC5C,BDNF,DISC1,KCNQ3,MYO10,HOMER2,PPFIA4,HIP1,SMARCD3,SNAP25,RABAC1,OR11H4,HERPUD1,SPATA7,BAIAP2,CPEB1,DAGLA,GRIK4,RIPOR2,SH3GL2,RPL28,FCHO2,WDR19,MPP2,PTPRN2,SEMA3A,CDH2,SHTN1,MME,DMXL2,EPHA3,PRKN,DNM3,SCAMP1,C4A,ABHD13,ADD2,KCTD12,NTRK3,CANX,KIF21B,NRXN1,PRR7,PCLO,PPP1R9A,SEMA6A,CTNNA2,TIAM2,CCDC120,EPB41L3,GPRIN1,CHRNA5,UNC13B,MYO3B,ADGRL1,DAB2IP,SCN2A,RAB27B,SYNGR3,KCNB2,GARS,FZD4,SHANK2,PREX1,NLGN4X,CHRNA6,VIM,AMIGO1,CD40,TTLL7,GABARAPL1,SNCA,CAMK2N1,HTR7,WFS1,ITGA2,RGS10,PAM,PTPRS,BMPR1A,SEPT5,MAPK10,CTTNBP2,COBL,STON2,PSPH,CTNND2,TENM1,MYO1D,FARP1,NECAB2,SLC6A9,ROBO2,ENO2,BMPR2,BACE1,APBB1,EPS8,BLVRB,LRP4,CLSTN2,GABRG2,KIF5C,PSD3,P2RY1,GABRR2,EPHB1,KCNC4,GDPD5,NEDD4,ARHGAP44,RGS17,MAP1A,SCN1B,TRIM3,NPTXR,SEPT3,ATP2B1,TRPM4,DLGAP1,SLC40A1,LZTS3,RAB3B,PTPN13,MPP1,RAPGEF2,SYBU,GRID1,ARHGAP32,RACK1,PALLD,HOMER3,MAP1B,DOCK7,ICA1,GNAO1,CTSV,GRIN2D,DLG2,KIF1B,NPHP1,ATP2B4,ATP1A3,SNPH |
| 7.787e-14 | -30.18 | membrane | cellular component | GO:0016020 | 9090 | 1006 | 18223 | 1724 |
DOC2A,GXYLT2,TRIM16L,FLVCR2,GRIK2,PRSS12,CNTNAP3,RECK,DNAJC3,MCOLN3,NPM1,CADM2,BCAN,SNX9,ABHD6,NOS1AP,PCDH7,BAG3,TGFBR3,PMAIP1,FAAH2,RAP2A,RAB26,TMED9,PPP2R2B,TMEM37,COG3,TSHR,CPE,SMIM20,DCC,WLS,CAP2,EXOC6B,TGFA,GJB2,LRRK2,HACD1,FEZ1,PRKAR2B,ABCC2,KCND3,F12,MFSD6,SLC7A1,ENPP1,ATP7B,ALDOA,ADRB1,INPP5F,DIRAS1,TPM1,TMEFF2,LPP,SCN5A,GNG12,TMEM63C,CYP2J2,ITGA6,TJP1,SLC36A4,GPSM2,BBS9,GRPEL2,BNIP1,FAM189A1,BACE2,CACNB2,FLRT3,LMAN2,CADPS2,LOXL4,FAM84B,ST8SIA1,NCAM1,MOXD1,JAM2,STXBP1,TSPAN9,GFRA1,RPS23,LRP12,CHRM3,HMGCR,FADS1,SLC37A1,KCNQ3,MYO10,MGST3,FASN,RYR2,HIP1,CALCRL,ST6GALNAC3,AIG1,SHISA2,SNAP25,OR11H4,ARRDC4,CLN5,CPEB1,CACHD1,TMCO3,SH3GL2,RPL28,QPCTL,CDH17,CLMN,LAPTM4B,SPRED3,CDH2,TRPC3,DOCK9,MTG1,TFCP2L1,BTC,DNM3,SCAMP1,GALNT12,C4A,GALNT6,MYO1B,ABHD13,RGS20,BEGAIN,PKP2,ADD2,IL13RA1,GRK6,NRXN1,LCP2,SLC19A2,CDS1,GPR15,RNF150,EPB41L3,PLPP1,TLR3,GPRIN1,CHRNA5,KMO,COL25A1,CNKSR3,FAM155B,ARL4D,SYNGR3,RAB27B,SNX10,KIAA1549,PERP,SCN3A,DOCK8,KCNB2,FZD1,COL6A2,GAPDH,EBPL,RNF145,FZD4,KCNH5,TRAM1L1,ADCY1,PCNX2,PXYLP1,RAB38,DSP,ASPH,FGFR1,MAGI3,GABARAPL1,GJC1,IRS2,ENTPD1,SLC39A14,CXCL10,ARHGAP21,GYPC,WFS1,GPR160,PEMT,PAM,P4HA1,ALG11,TNFSF15,PLD5,LRRC27,RAB30,C2orf88,SERINC5,FARP1,ANKRD13B,TMEM132C,C1QTNF3,EDA2R,ROBO2,GCAT,BACE1,FZD8,CD276,IPO5,BIK,UBAC2,NKAIN2,PSD3,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,KCNC4,TSPAN17,NEO1,LRRN1,MCF2L,GHR,MYO6,NPTXR,FES,PARP9,ULBP1,TRPM4,B9D1,VEGFC,LZTS3,RAB6B,RAPGEF2,ELOVL3,RASA3,GAREM1,ATP11A,RACK1,SNTB1,HEG1,GALNT3,PTPRC,TRIB3,RPL12,PCDHB7,PLOD2,PLPPR2,AKT3,GNAO1,OSBPL5,SRD5A3,XBP1,SLCO5A1,PIP5KL1,HK1,ATP2B4,DCBLD1,CCDC126,CACNG3,FGF13,TRIM16,SYT12,LILRB1,ASS1,NRN1,ITPR2,MGAT5B,SYT14,PLS3,RND2,CPNE2,TM9SF2,KCNAB1,KCNN2,SEC16B,TCAF2,HPS1,MARVELD2,ITGB3,TMEM86A,TMEM143,LIN7A,TLN2,TMEM132E,TLR4,ENO1,DBN1,ITGB7,CD55,KCNIP3,SLC3A2,GCNT2,MARK1,ATF4,ABCC4,ANK2,GDPD1,PLPP2,NFE2L1,CR2,TMEM200C,PLEKHA1,PLEKHB1,TSKU,SPNS1,KCNMB4,INSIG1,GNB4,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,ADGRA3,ADGRL2,TC2N,HS6ST3,RRAGD,CHMP4C,TYRO3,KCNV1,RGS16,LGALS3,STXBP5L,HID1,ITPRIP,RASL11B,MLC1,IL18R1,PGAP1,SPIRE1,RNF180,GALNT1,SEMA4F,IGF1R,ABCA5,BCHE,FRAS1,PDE10A,HS3ST5,LRP6,ADCY6,BNIP3,NIPAL2,SLCO4C1,FAR2,FBXL2,PTPRCAP,CKAP4,PAK1,CHSY3,TMEM178B,NDUFA4L2,FGFR4,UNC5C,B3GLCT,BTNL9,SLC27A2,RNF170,HOMER2,MGAT4B,EFNA3,GPSM1,SPATA13,TMTC4,SLITRK5,OBSCN,SDK1,GPR19,LDHD,BAIAP2,NEGR1,KCNK15,GRIK4,MFSD2A,CSF1,SLC2A6,PLD1,RNF122,SMCO4,TESC,MME,SFN,AKAP5,DOCK1,LPCAT2,XYLT1,RNF24,OR51B4,NTRK3,FAM198B,SLC7A2,SEZ6L2,LPIN3,PRR7,SEMA6A,CBLN1,CTNNA2,CYP26A1,SLC22A17,TACC2,ZDHHC6,ZDHHC23,ADGRL1,SCN2A,CLVS2,TMEM56,HRASLS,RPS13,EVL,TMEM67,EVA1A,TUBA1A,LRRC8B,TMEM65,RNF125,CHRNA6,VIM,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTPRJ,RNF217,GBP1,PTK7,KCNG1,ITGA2,ABI3,PTPRS,MAOA,HGF,SUSD4,SEPT5,MBOAT2,RETREG1,CNTN1,ARFGEF3,MAN2B2,TENM1,PCDH18,LPAR2,SLC6A9,NECAB2,IL32,BMPR2,GRB14,APBB1,BLVRB,MCTP2,GABRG2,SELL,RASD1,SFXN3,USP30,ARHGAP44,SLC35F1,TTC1,TECPR1,FUT9,RASD2,KCNMB3,SGK1,PRICKLE2,TSPAN13,KLF9,SYK,SLC45A3,ATP2B1,PCSK6,DLGAP1,LITAF,PRICKLE1,FERMT2,EXOG,FNDC3A,PALLD,NPDC1,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,CD37,TMEM237,FAT4,FMO4,SH3BGRL2,DLG2,MYRF,RPL4,SLC22A15,SLC1A5,TBC1D4,PTGES,KIF1B,FILIP1,CACNA2D1,FAM171B,MYCBP2,CGN,ACVR1,LANCL3,SIDT1,LGR4,ATP8A1,LDLR,VAMP8,ENAH,PRKCA,RAC3,AARS,NCS1,STK24,SLC9A7,ZFYVE28,SLC16A2,SLC22A18,SERINC2,KCNS3,NDUFB8,ATRNL1,PACSIN1,THSD1,TBC1D8,GLDC,GDAP1,ERGIC1,ACVR1C,SLC9C1,LRMP,BNIP3L,AGO4,SLC25A28,ACVR2B,ZDHHC14,GPC6,GNAI1,GPR150,SFXN1,SPATA9,ENPP6,NCKAP1L,RASGRF2,ENTPD7,B3GALT2,DSEL,MFSD4A,SPRY4,SPART,UNC5B,NRP1,LZTS1,EFNB2,SEMA6B,LRFN5,MRC2,INPPL1,ALOX5AP,CELSR1,PTPRD,GABRB2,SCN8A,ST6GAL1,DHCR24,MFSD13A,SLC25A27,MRPL22,WDFY4,SLC1A3,TNFRSF10C,APBA1,TNFRSF19,CHD5,GAS1,MYORG,RPL13A,PRRG4,MTUS1,MCOLN2,GBGT1,RALGPS2,SLC7A11,CNTN4,MSMO1,PIK3AP1,PDZD7,SCARF2,SREBF1,PRKG1,OPN3,GRIP1,SLC16A9,MPDZ,TSPAN12,FAM155A,GPR161,RIMS2,IGSF3,RNF152,EPB41L5,PTCH2,RPL26,QSOX1,DISC1,SLC36A1,PLEKHA8,VLDLR,RAPGEF4,DCHS1,KIAA1324L,PACSIN3,TTYH2,PEX5L,RABAC1,PLCB1,FAM162A,TMEM74,MMP15,DAGLA,XKR9,PLEKHH2,VPS37D,PMEPA1,MPP2,SQLE,DHCR7,PLA2G4A,EPHA3,FRMPD3,AMOTL1,TCTN2,ELOVL4,RASAL2,ST14,RNF144A,RHOD,GPR65,MSR1,PLXNA2,CHUK,KCTD12,TMEM170B,DDR1,TBC1D30,TIAM2,ZFYVE9,TMEM53,ERG28,SCRN1,NBEA,DAB2IP,MARCKS,PDE4D,SERPINH1,GATM,ATP6AP1L,GAB2,VNN2,B3GALT1,TMEM43,CYB5R2,SFXN4,SHANK2,PANK1,PREX1,NLGN4X,PRKCQ,ATP1B1,TRIQK,ATP10D,SNCA,DCBLD2,PATJ,HTR7,IKZF3,POPDC3,PRKCB,ASIC1,MAP3K21,HPGD,GRB10,BMPR1A,HS3ST3B1,ATG5,MAPK10,NR3C2,STON2,COBL,DENND5B,HACE1,RPS20,ANO10,MYO1D,ANKRD13D,PLSCR4,GLIPR1L1,ATP9A,EPS8,ARL2,GPR180,GABRR2,NDFIP2,RGS7,GDPD5,SLC35G2,PHLDA2,NEDD4,ADGRB2,RGS17,LRRC55,SOAT2,MGAT1,GPR155,RMDN2,PRKG2,RALGAPA2,SLC6A15,FIG4,CERS4,DYNC2H1,ERRFI1,SPRY2,B4GALT6,TMC7,SLC40A1,VAV3,PXN,ARAP2,ARHGEF28,PTPN13,MPP1,AGPAT4,CACNA1E,RPL21,TMEM126A,ZDHHC15,GUCY1A2,SKAP1,GPR137C,GPLD1,FGR,OR2T33,TERT,CLDN12,PLXDC2,MCC,SVIL,GRIN2D,CERS1,TNFRSF17,B4GALT7,OCLN,LARP1,SLC43A1,ATP1A3,MPZL3,ACSL1,UGT8,KIF5A,SLC2A13,CACNB4,DNER,ABHD4,KREMEN1,HMCN1,SLCO3A1,CHST10,F3,FKBP11,GSDME,CYP51A1,RTN1,EPCAM,SLC10A7,TRPC1,CNNM2,SLC2A12,HRK,EPHB6,CTTN,PTPRE,OR2W3,GALNT18,SLIT2,IL1RAP,PRKACB,RASGRP1,PDGFRB,LAMP3,CYP1B1,ATL1,TNK2,GPM6A,SKAP2,CEMIP2,JPH1,YAP1,ROR1,TMEM47,GRK3,TMEM132B,GSN,TMEM150B,GPRC5B,HPSE,NCAM2,ITGBL1,OXTR,TNFSF4,APBA2,FNDC10,MAGI2,SLC9B1,FRMD5,PCSK5,UST,GPR63,SV2B,FN1,RHOBTB1,SEC24D,SCART1,BVES,STXBP6,ELOVL7,CYP4V2,ATP6V1E2,LAMC3,SCD,GALNT13,CHSY1,CD7,SPINK5,ADGRG6,PCDHB14,RNF141,EEF2,SLC30A4,CA2,RPS11,VSIR,RNF148,NCEH1,LRP3,SNX7,NOS3,PCDH10,CDH26,GPR176,IL17RD,ATP5IF1,PODXL2,RHOQ,SLITRK2,PARD3B,EDEM3,SDC3,WWC1,CATSPERE,GALNT17,B4GALNT3,SLC46A3,STEAP1,HERPUD1,GLCE,TMEM154,RIPOR2,ADGRB3,FCHO2,FAT1,NCR3LG1,SH3BP4,RAB31,HK2,PTPRN2,TMEM117,DISP2,FNBP1L,XKR4,OSBPL6,DIRC2,CREB3L2,CXCR5,DMXL2,SORBS1,CELSR3,IL15,PSTPIP2,PLEKHA5,CANX,DOCK2,SCIN,CD53,UNC13B,PDZD8,ERO1B,KAZN,PPFIBP1,REEP1,FABP6,MAP7,ACVR2A,STEAP3,FHIT,PROS1,MET,TMEM120B,NTNG1,HSPA2,SEMA6C,ALG10B,SUSD3,DPP10,GCA,PHLDB2,FER,ANTXR2,PRAME,PTPRU,SLC39A8,PTPN6,TES,C3orf52,SYNJ2BP,AMIGO1,CD40,DOCK5,CAMK2N1,LMLN,TMPRSS9,RGS10,DISP1,CYP2U1,RNF130,LIFR,MAST1,OR51B5,TNIK,ENO2,TSPAN15,CLGN,ARHGEF11,LRP4,CMTM8,TNFSF13B,CLSTN2,CUEDC2,FAM174B,SEL1L3,MCU,FSD1,RAB11FIP5,KCNJ4,CHN2,SCN1B,LHFPL6,PRKCD,DSG2,EHD3,KIAA0319,MARCH3,AFAP1L2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,TESPA1,USP2,RAB3B,CRIM1,NR4A1,CYTH3,SYBU,ASAP3,GRID1,PRRG1,MARS,AGAP2,PHACTR2,ARHGAP32,TLR6,GALNT14,NAALADL2,LRAT,LEPR,MAP1B,DPY19L2,GPR37,ICA1,MYADM,EDA,MFSD9,RND3,MPP7,GCSAM,ACER2,PRCP,CTSV,THSD7B,SLC7A5,SLC18B1,KIF21A,RPS12,GEM,IL9R,NPHP1,MMP16,SLC16A10,ABCG1,STOM,SNPH |
| 8.454e-14 | -30.10 | GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | MSigDB lists | GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 501 | 104 | 17377 | 1707 |
ID1,CELSR3,ST14,RBFOX2,KIF5A,PLXNA2,GATA3,COL18A1,ENAH,NRXN1,RADIL,SEMA6A,CTNNA2,TGFBR3,EOMES,COL25A1,ITGB3,MET,ETV1,SLIT2,NTNG1,SEMA6C,SNAI2,NKX2-1,ATL1,FER,ITGB7,EVL,DCC,FZD4,PTPN6,ADCY1,FEZ1,PRKCQ,WNT11,AMIGO1,ATOH1,ARHGEF26,TSKU,MAP2,LAMB1,SEMA3C,HGF,UNC5B,NRP1,COBL,CTNND2,HEY1,MEF2C,EFNB2,BCL11B,TYRO3,LATS2,LRFN5,FARP1,ROBO2,FN1,BVES,LRP4,APBB1,OPHN1,KIF5C,LAMC3,SLC1A3,EPHB1,NEO1,CHN1,LRRC55,NUMBL,CNTN4,SEMA4F,LRRN1,PDZD7,SCN1B,FLRT3,LRP6,NCAM1,STXBP1,ZNF385A,DPYSL5,PAK1,EPB41L5,BDNF,UNC5C,MSX1,SLITRK2,VLDLR,EFNA3,FERMT2,SLITRK5,PALLD,PEAK1,BAIAP2,MAP1B,HEG1,DKK1,RERE,DOCK7,HEYL,MATN2,BMP4,NKX2-8,SEMA3A,SIX2 |
| 9.708e-14 | -29.96 | oesophagus-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-carcinoma-adenocarcinoma | 13493 | 1434 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,TMED9,PPP2R2B,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,CAB39L,TMOD2,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,SLC19A2,TLR3,ALDH1L1,ZNF365,DNAH5,MYT1,ANKRD18B,KCNB2,FZD1,C3orf67,COL6A2,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,FZD8,ESRP1,CD276,BACE1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,KLF12,ERN1,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,EFNA3,GPSM1,STRADB,SLITRK5,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,SLC2A6,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,HRASLS,INTU,CSN2,TMEM65,LRRC8B,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,PRICKLE1,FERMT2,PALLD,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,NBL1,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,SPEG,ASNS,ZNF438,SHF,PDE4D,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATP1B1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,STON2,PURG,MID1,HACE1,MYO1D,PLSCR4,EPS8,HERC5,NDFIP2,TPD52L1,INPP1,PHLDA2,AFF2,GPR155,DYNC2H1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,CERS1,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,SGK2,GSN,TMEM150B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,SDC3,STEAP1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,OSBPL6,XKR4,DMXL2,SORBS1,ARHGAP22,HECW2,COL18A1,COBLL1,PIBF1,SCIN,PDZD8,CDC14B,KAZN,C12orf60,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,AMIGO1,CD40,BCL11A,ZNF569,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,TSPAN15,CMTM8,TNFSF13B,COL4A5,IGF2BP2,OVOL2,FAM174B,SEL1L3,BMP6,MCU,RAB11FIP5,FSD1,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,BNIP1,KIAA1671,FAM189A1,BACE2,CACNB2,PRELID2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,JAKMIP3,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,WWTR1,INPP4B,PLEKHG1,P4HA1,RCN3,ALG11,TNFSF15,DBP,PLD5,KLHL31,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,TPT1,NMNAT3,NBPF4,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,CD55,GCNT2,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,ITPRIP,ZCCHC24,UBASH3B,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,KIAA0895,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,CSF1,MFSD2A,HEYL,TESC,MME,SIX2,AVPI1,CFH,LPCAT2,XYLT1,OR51B4,ZNF83,FAM198B,LPIN3,SEZ6L2,PCLO,CBLN1,CYP26A1,FAM131B,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,KCNG1,ABI3,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,KIAA1211,DLGAP1,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,PAX9,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,VWA5A,PLTP,TBC1D8,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,RUNDC3B,OPN3,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,ZNF827,TMEM53,NELL2,SCRN1,NBEA,DAB2IP,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,ZNF396,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,THOC3,DENND5B,ANO10,WASF3,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,RALGAPA2,SLC6A15,FIG4,GFI1,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,SLC43A1,ATP1A3,EXPH5,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,FAM27C,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,RIMKLA,YPEL2,CYP4V2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CA2,FAM107B,EBF4,NCEH1,NOS3,GPR176,ANKRD20A2,IL17RD,PARD3B,EDEM3,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,GULP1,MDH1B,WWC2,MET,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,GRID1,OGDHL,MEI1,PRRG1,MARS,AGAP2,PHACTR2,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SLC16A10,STOM,SNPH |
| 1.099e-13 | -29.84 | neurogenesis | biological process | GO:0022008 | 1542 | 235 | 17256 | 1658 |
UGT8,FGF13,KIF5A,LDLR,MCOLN3,GATA3,HDGFL3,ENAH,CHAC1,PRKCA,DNER,RAC3,STK24,NCS1,GSDME,SKI,RND2,EOMES,RAP2A,CTTN,PACSIN1,ETV1,SLIT2,IL1RAP,NKX2-1,DBN1,ATL1,GPM6A,ATF4,MARK1,DCC,LRRK2,YAP1,FEZ1,ROR1,EML1,TSKU,GSN,TCF7L1,GPRC5B,NCAM2,NCKAP1L,MAP2,PLK2,AHNAK2,SEMA3C,SERPINI1,INPP5F,DLX2,SPART,UNC5B,NRP1,MAGI2,NEUROG2,MEF2C,UST,BCL11B,EFNB2,LRFN5,RUNX2,FN1,CELSR1,PTPRD,GABRB2,OPHN1,LAMC3,SLC1A3,PHGDH,SPINK5,FOXG1,ADGRG6,CHD5,DOK5,DDIT4,CHN1,NUMBL,NAV1,CNTN4,SEMA4F,EEF2,FRY,PDZD7,BCHE,GATA2,FLRT3,PRKG1,GRIP1,LRP6,ADCY6,BNIP3,NCAM1,STXBP1,GFRA1,RIMS2,LRP12,PAK1,DPYSL5,UNC5C,BDNF,DISC1,SLITRK2,DCHS1,VLDLR,EFNA3,SMARCD3,SLITRK5,PRDM1,SNAP25,SDK1,CLN5,BAIAP2,NEGR1,DAGLA,ADGRB3,SH3GL2,HEYL,CSF1,MATN2,CLMN,NKX2-8,CDH2,SEMA3A,SHTN1,EPHA3,PRKN,NBL1,ZSWIM5,ID1,DNM3,CELSR3,RBFOX2,PLXNA2,HECW2,NTRK3,NRXN1,DDR1,CBLN1,SEMA6A,PPP1R9A,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,ZNF521,BCL6,DAB2IP,ZNF488,ZNF365,NTNG1,SEMA6C,FZD1,GAB2,SSH3,EVL,FZD4,PRDM13,SHANK2,ADCY1,PREX1,NLGN4X,PRKCQ,WNT11,VIM,SATB2,ATOH1,AMIGO1,JAM3,FGFR1,BCL11A,IRS2,NRG3,PTK7,LAMB1,PTPRS,GRB10,HGF,BMPR1A,MAPK10,COBL,CTNND2,CNTN1,TENM1,TNIK,WASF3,FARP1,ROBO2,BMPR2,PLAG1,FZD8,LRP4,APBB1,KIF5C,PRDM8,P2RY1,GAS6,EPHB1,GDPD5,BMP6,NEDD4,ARHGAP44,NEO1,NKX6-1,LRRC55,IRX5,MAP1A,LRRN1,SCN1B,KIAA0319,SGK1,FIG4,DYNC2H1,NPTXR,GFI1,SLC45A3,FES,VEGFC,PDLIM7,LZTS3,RAPGEF2,RERE,MAP1B,DKK1,CEBPB,ID3,DOCK7,FAT4,TERT,GNAO1,XBP1,MYRF,BMP4,SHOX2,FOXA1,SNPH |
| 1.122e-13 | -29.82 | hepatocellular_carcinoma | COSMIC cancer mutations | hepatocellular_carcinoma | 15259 | 1579 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RUFY4,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,PLAGL1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,CD40,CENPV,BATF3,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,F12,MFSD6,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,SYT12,FHDC1,ASS1,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,SLCO4C1,PAK1,CHSY3,FGFR4,MID2,UNC5C,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,NAP1L5,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,LINC00896,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,OTUD1,CA2,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,ANKRD20A2,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.122e-13 | -29.82 | liver-carcinoma-hepatocellular_carcinoma | COSMIC cancer mutations | liver-carcinoma-hepatocellular_carcinoma | 15259 | 1579 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RUFY4,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,PLAGL1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,CD40,CENPV,BATF3,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,F12,MFSD6,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,SYT12,FHDC1,ASS1,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,SLCO4C1,PAK1,CHSY3,FGFR4,MID2,UNC5C,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,NAP1L5,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,LINC00896,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,OTUD1,CA2,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,ANKRD20A2,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.137e-13 | -29.81 | small_cell_carcinoma | COSMIC cancer mutations | small_cell_carcinoma | 10152 | 1132 | 17385 | 1698 |
ARHGAP26,THOC5,GRIK2,CNTNAP3,TUBE1,NPM1,CEBPA,BCAN,KIAA1217,SNX9,SKI,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,FGF17,INTS6,ENPP1,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,TPM1,DNHD1,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,SRGAP1,TOX,CADPS2,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,EFHC2,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SNAP25,ZBBX,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,CLMN,HOXD13,CDH2,DOCK9,ADD2,GRK6,TLR3,FAM133A,DNAH5,ZNF365,MYT1,SNX10,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,PFKFB2,ADCY1,WNT11,ASPH,MAGI3,GJC1,CXCL10,ARHGAP21,PDLIM3,LAMB1,RAB30,ANKRD13B,WDR17,GCAT,FZD8,CD276,PLAG1,BIK,CBS,SLC12A6,GAS6,EPHB1,BEX2,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,PIP5KL1,BMP4,ATP2B4,CRISPLD1,TLL2,PHACTR3,CACNG3,FGF13,TRIM16,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RPS6KA2,CPVL,SEC16B,ITGB3,TMEM143,MPPED2,ENO1,RAPGEF5,DBN1,MARK1,PNRC1,COL4A3,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,DYRK1B,TRIM9,TCF7L1,KCNMB4,ERN1,HS6ST3,RRAGD,KCNV1,RUNX2,STXBP5L,SORBS3,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,GAN,HS3ST5,LRP6,ADCY6,FAR2,DPYSL5,MGAT4B,GPSM1,STRADB,MAFB,OBSCN,SLITRK5,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,DDX60L,TACC2,BCL6,EEPD1,MYH15,IGFBP3,INTU,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,USP30,SLC35F1,FOXP2,SGK1,KIAA0408,SYK,ATP2B1,DUSP1,LRRIQ1,FOXN3,CRIP2,PALLD,ILDR2,MGMT,SMPDL3B,DKK1,EBF1,DOCK7,FBN1,SH3BGRL2,PTGES,CACNA2D1,ZNF235,FAM171B,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,KCNS3,GLDC,ERGIC1,ACVR1C,WISP3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,BMP1,MAPK13,SERPINI1,DSEL,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,ST6GAL1,MLF1,LRRC49,APBA1,TNFRSF19,GAS1,ABLIM1,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,CPXM2,GRIP1,FAM155A,PRR16,GPR161,BOD1,PTCH2,DISC1,RPL26,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,THBS4,LRRIQ3,MPP2,DYNC2LI1,SQLE,DHCR7,SLFN5,SMYD3,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ZNF438,ALDOC,PDE4D,GAB2,TRDMT1,B3GALT1,SHANK2,PREX1,NLGN4X,SATB2,ATF3,ATOH1,PYGO1,ATP10D,ISG20,ZNF711,IKZF3,CCNA1,BMPR1A,COBL,STON2,MID1,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,RASSF8,LRRC55,AFF2,GPR155,TBC1D9,SMAD6,TMC7,VAV3,SLC40A1,ALDH2,SH3BP2,PXN,PTPN13,ZDHHC15,UCHL3,HOXA1,TERT,MCC,SVIL,TNFRSF17,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,PPM1E,SIPA1L2,ANKFN1,CNNM2,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GPRC5B,HPSE,TNFSF4,PPARGC1A,MAGI2,PCSK5,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,FBXO4,CHADL,CHSY1,SPINK5,PCDHB14,RNF141,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,PCDH10,HBG2,RHOQ,SLITRK2,SDC3,STEAP1,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COBLL1,CANX,CD53,PDZD8,CDC14B,PPFIBP1,C12orf60,FABP6,ACVR2A,FHIT,PROS1,NTNG1,SEMA6C,ALG10B,PRAME,PTPRU,PTPN6,MVD,TCEAL3,CD40,BCL11A,ZNF569,ARMC4,MAGEA12,KPNA3,TRIM34,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,SSX1,TNFSF13B,IGF2BP2,COL4A5,OVOL2,BMP6,MCU,RAB11FIP5,KCNJ4,PRKCD,STC2,AFAP1L2,RBMS2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,IL9R,ABCG1,GXYLT2,PDE1B,PRSS12,AASS,DNAJC3,CADM2,STAT5B,DOCK3,CA8,NOS1AP,EYA4,EPDR1,PCDH7,BAG3,FBXO32,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,CAP2,TGFA,CA13,ZNF266,ALDOA,ARHGAP28,TMEFF2,MEF2C,LPP,CARS,LATS2,GNG12,STOX2,CYP2J2,SYCP2,RSL24D1,BNIP1,KIAA1671,FAM189A1,BACE2,ZIC5,LOXL4,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,CHRM3,HMGCR,PNP,MYO10,STAT4,CALCRL,SMARCD3,RYR2,PLS1,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,BTC,DNM3,TMSB15A,GALNT12,LRRCC1,RGS20,PKP2,IL13RA1,NRXN1,COLEC10,TXNRD3,EPB41L3,RNF150,GPRIN1,DACT1,RTKN2,PJA1,RAB27B,ARL4D,FAM155B,SCN3A,DOCK8,PERP,DZANK1,GARS,RNF145,FZD4,KCNH5,RAB38,FGFR1,IRS2,IQCK,IQCH,GYPC,INPP4B,PAM,ALG11,P4HA1,TNFSF15,PLD5,C2orf88,FARP1,EDA2R,ROBO2,C1QTNF3,IPO5,NKAIN2,CREB5,P2RY1,PKN1,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,NPTXR,MYO6,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,SNTB1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,BTRC,FOXA1,DCBLD1,TPT1,NBPF4,TRIM2,SYT12,FHDC1,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,EOMES,HPS1,MARVELD2,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,ABCC4,PLEKHA1,BATF,NT5DC2,PLEKHB1,TSKU,MAP2,P4HA2,GNB4,CCDC146,TECPR2,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,RASL11B,SETBP1,MLC1,PGAP1,IL18R1,HSPA12B,KIAA0895,IGF1R,ABCA5,GATA2,BCHE,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,SLC27A2,SPATA13,TMTC4,PPFIA4,WDR25,TEX9,MAPKAPK2,NAP1L5,HEYL,SFN,MME,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,FAM198B,LPIN3,SEZ6L2,PCLO,CYP26A1,FAM131B,SLC22A17,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,TMEM67,UROS,THSD4,FGF12,FBXO36,PAGE5,FRK,JAM3,SMAD3,RANBP2,NRG3,PTK7,KCNG1,ITGA2,SEPT5,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,GRB14,RUSC2,NLRP14,BLVRB,HBE1,PPP2R3A,MAP1A,RASD2,EIF1,SH3PXD2B,PCK2,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,ZNF808,PAX9,TBC1D4,FILIP1,CGN,MYCBP2,PAGE1,ACVR1,LANCL3,SIDT1,DUSP8,PPFIBP2,GATA3,ADAMTS6,DACH2,RAC3,STK24,CFHR1,FAM168A,SLC16A2,CHRDL1,ATRNL1,SP140,VWA5A,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,TNS1,ACVR2B,SAV1,AHRR,SFXN1,HLF,NCKAP1L,PLK2,RASGRF2,UNC5B,TANC2,LZTS1,INPPL1,EHHADH,CELSR1,ALOX5AP,ZHX3,PTPRD,SCN8A,OPHN1,SLC25A27,GTF2IRD1,WDFY4,TNFRSF10C,DYNC1I1,ADSSL1,CHD5,PRRG4,MECOM,MCOLN2,NAV1,CNTN4,PIK3AP1,RUNDC3B,TSPAN12,MPDZ,SAMD13,RIMS2,RNF152,IGSF3,QSOX1,PLEKHA8,TBC1D8B,COL4A4,KIAA1324L,TTYH2,PLCB1,ZNF558,FAM162A,DAGLA,PKN3,PMEPA1,IQSEC2,AMPD1,ACSM3,PLA2G4A,EPHA3,FRMPD3,PCSK1N,RASAL2,ELOVL4,RNF144A,GPR65,CHUK,NUDT12,TBC1D30,ZNF827,NELL2,STARD4,DAB2IP,NAP1L3,SERPINH1,VNN2,PDK1,TMEM43,PNMA6A,PRKCQ,TBC1D16,HTR7,PRKCB,GRB10,CTTNBP2,NR3C2,WASF3,MXI1,ATP9A,ARL2,GPR180,RGS7,GDPD5,NEDD4,RGS17,SGK3,RALGAPA2,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,ARAP2,SYNPO2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,MYOM2,ATP1A3,SLC43A1,EXPH5,MVK,KIF5A,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,KREMEN1,QPRT,FKBP11,ARHGEF10L,RTN1,AKAP7,DLX6,POF1B,SLC2A12,HRK,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,GPM6A,CAPN5,ROR1,RNF44,SERGEF,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,BCL11B,FN1,SEC24D,JDP2,ELOVL7,CYP4V2,LAMC3,ATP6V1E2,GALNT13,SATB1,DDIT4,OTUD1,CA2,EBF4,NOS3,IL17RD,GPR176,MSTN,PARD3B,EDEM3,DUSP9,WWC1,PRDM1,RAI14,HK2,EGFL7,DIRC2,CREB3L2,CXCR5,NEK10,ZSWIM5,CELSR3,PLEKHA5,MORC4,TDRKH,BCL6B,DOCK2,ZSCAN5A,COL22A1,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,POU2F2,MET,WWC2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,TTLL7,C1orf174,TPK1,MSC,LMLN,BACH2,DISP1,LIFR,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,CLSTN2,NOTUM,RPL34,CHN2,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,RAB3B,ESRRG,NR4A1,CYTH3,GRID1,OGDHL,PRRG1,MARS,PHACTR2,AGAP2,CCNG1,ARHGAP32,ZFPM2,C3orf70,RERE,MAP1B,GPR37,ADAMTS17,NACC2,MPP7,MAP2K6,THSD7B,SLC7A5,KIF21A,GEM,MMP16,SLC16A10,SNPH |
| 1.160e-13 | -29.79 | membrane part | cellular component | GO:0044425 | 6613 | 767 | 18223 | 1724 |
GXYLT2,FLVCR2,CNTNAP3,GRIK2,RECK,DNAJC3,MCOLN3,CADM2,BCAN,SNX9,ABHD6,NOS1AP,PCDH7,TGFBR3,FAAH2,RAB26,TMED9,TMEM37,TSHR,CPE,SMIM20,DCC,WLS,TGFA,GJB2,LRRK2,HACD1,PRKAR2B,ABCC2,KCND3,MFSD6,SLC7A1,ENPP1,ATP7B,ADRB1,INPP5F,TPM1,TMEFF2,SCN5A,TMEM63C,GNG12,CYP2J2,ITGA6,TJP1,SLC36A4,GPSM2,BBS9,GRPEL2,BNIP1,FAM189A1,BACE2,CACNB2,FLRT3,CADPS2,LMAN2,ST8SIA1,NCAM1,MOXD1,JAM2,STXBP1,TSPAN9,GFRA1,CHRM3,LRP12,HMGCR,FADS1,SLC37A1,KCNQ3,MYO10,MGST3,HIP1,CALCRL,RYR2,ST6GALNAC3,AIG1,SHISA2,SNAP25,OR11H4,CLN5,CPEB1,TMCO3,CACHD1,QPCTL,CDH17,CLMN,LAPTM4B,CDH2,TRPC3,BTC,DNM3,SCAMP1,GALNT12,GALNT6,ABHD13,PKP2,ADD2,IL13RA1,NRXN1,LCP2,SLC19A2,CDS1,GPR15,EPB41L3,RNF150,PLPP1,TLR3,CHRNA5,KMO,COL25A1,CNKSR3,SYNGR3,FAM155B,RAB27B,SNX10,KIAA1549,PERP,SCN3A,DOCK8,KCNB2,FZD1,EBPL,RNF145,FZD4,KCNH5,TRAM1L1,ADCY1,PCNX2,PXYLP1,DSP,ASPH,FGFR1,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,GYPC,GPR160,PEMT,WFS1,PAM,ALG11,TNFSF15,PLD5,SERINC5,FARP1,TMEM132C,EDA2R,ROBO2,BACE1,FZD8,CD276,BIK,UBAC2,NKAIN2,PSD3,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,KCNC4,TSPAN17,NEO1,LRRN1,GHR,NPTXR,MYO6,FES,ULBP1,TRPM4,LZTS3,RAPGEF2,ELOVL3,RASA3,ATP11A,RACK1,SNTB1,HEG1,PTPRC,GALNT3,PCDHB7,PLOD2,PLPPR2,GNAO1,SRD5A3,OSBPL5,XBP1,SLCO5A1,DCBLD1,ATP2B4,CACNG3,FGF13,SYT12,LILRB1,NRN1,ITPR2,MGAT5B,SYT14,KCNN2,SEC16B,TM9SF2,KCNAB1,HPS1,MARVELD2,ITGB3,TMEM86A,TMEM143,LIN7A,TMEM132E,TLR4,ITGB7,CD55,SLC3A2,KCNIP3,GCNT2,ATF4,ABCC4,ANK2,GDPD1,NFE2L1,PLPP2,CR2,TMEM200C,PLEKHA1,PLEKHB1,SPNS1,KCNMB4,INSIG1,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,ADGRA3,ADGRL2,RRAGD,CHMP4C,HS6ST3,TYRO3,KCNV1,RGS16,STXBP5L,LGALS3,HID1,MLC1,PGAP1,IL18R1,SPIRE1,RNF180,GALNT1,IGF1R,SEMA4F,ABCA5,FRAS1,HS3ST5,LRP6,ADCY6,BNIP3,NIPAL2,PTPRCAP,SLCO4C1,FAR2,CKAP4,PAK1,TMEM178B,CHSY3,FGFR4,NDUFA4L2,UNC5C,B3GLCT,BTNL9,RNF170,SLC27A2,MGAT4B,HOMER2,GPSM1,SPATA13,EFNA3,TMTC4,SLITRK5,SDK1,GPR19,BAIAP2,NEGR1,GRIK4,KCNK15,MFSD2A,CSF1,SLC2A6,PLD1,RNF122,TESC,SMCO4,MME,AKAP5,LPCAT2,XYLT1,RNF24,OR51B4,NTRK3,FAM198B,SLC7A2,SEZ6L2,LPIN3,PRR7,SEMA6A,CBLN1,CTNNA2,CYP26A1,SLC22A17,ZDHHC6,ADGRL1,ZDHHC23,SCN2A,TMEM56,HRASLS,TMEM67,EVA1A,TUBA1A,TMEM65,LRRC8B,RNF125,CHRNA6,FRK,JAM3,RANBP2,NRG3,PTPRJ,RNF217,PTK7,KCNG1,ITGA2,MAOA,PTPRS,SUSD4,MBOAT2,ARFGEF3,CNTN1,RETREG1,TENM1,PCDH18,LPAR2,SLC6A9,BMPR2,APBB1,MCTP2,SELL,GABRG2,SFXN3,USP30,ARHGAP44,SLC35F1,TECPR1,FUT9,KCNMB3,SGK1,TSPAN13,SYK,SLC45A3,ATP2B1,DLGAP1,LITAF,FERMT2,FNDC3A,NPDC1,ILDR2,SMPDL3B,HOMER3,CD37,TMEM237,FAT4,FMO4,DLG2,MYRF,SLC22A15,SLC1A5,PTGES,CACNA2D1,FAM171B,ACVR1,SIDT1,LGR4,ATP8A1,LDLR,VAMP8,PRKCA,NCS1,SLC9A7,SLC16A2,SLC22A18,SERINC2,NDUFB8,KCNS3,ATRNL1,PACSIN1,THSD1,GDAP1,ERGIC1,SLC9C1,ACVR1C,LRMP,BNIP3L,SLC25A28,ACVR2B,ZDHHC14,GPC6,GPR150,GNAI1,SFXN1,SPATA9,NCKAP1L,ENPP6,ENTPD7,RASGRF2,B3GALT2,MFSD4A,DSEL,SPRY4,NRP1,UNC5B,LZTS1,EFNB2,SEMA6B,LRFN5,MRC2,ALOX5AP,CELSR1,PTPRD,GABRB2,ST6GAL1,SCN8A,DHCR24,MFSD13A,SLC25A27,TNFRSF10C,WDFY4,SLC1A3,TNFRSF19,GAS1,MYORG,PRRG4,MCOLN2,GBGT1,CNTN4,SLC7A11,MSMO1,SREBF1,SCARF2,OPN3,GRIP1,SLC16A9,MPDZ,TSPAN12,FAM155A,GPR161,RIMS2,IGSF3,RNF152,EPB41L5,PTCH2,DISC1,QSOX1,SLC36A1,DCHS1,VLDLR,KIAA1324L,TTYH2,RABAC1,FAM162A,TMEM74,DAGLA,MMP15,XKR9,VPS37D,PMEPA1,MPP2,SQLE,DHCR7,EPHA3,PLA2G4A,AMOTL1,ELOVL4,RASAL2,TCTN2,RNF144A,ST14,GPR65,PLXNA2,MSR1,CHUK,KCTD12,TMEM170B,DDR1,TMEM53,ERG28,DAB2IP,PDE4D,SERPINH1,ATP6AP1L,VNN2,B3GALT1,TMEM43,SFXN4,CYB5R2,SHANK2,PANK1,NLGN4X,PRKCQ,ATP1B1,TRIQK,ATP10D,PATJ,DCBLD2,SNCA,HTR7,POPDC3,ASIC1,MAP3K21,HPGD,HS3ST3B1,BMPR1A,NR3C2,DENND5B,ANO10,MYO1D,PLSCR4,GLIPR1L1,ATP9A,EPS8,ARL2,GPR180,GABRR2,RGS7,NDFIP2,GDPD5,SLC35G2,NEDD4,ADGRB2,LRRC55,SOAT2,MGAT1,GPR155,RMDN2,PRKG2,SLC6A15,CERS4,ERRFI1,SPRY2,B4GALT6,TMC7,SLC40A1,MPP1,CACNA1E,AGPAT4,TMEM126A,ZDHHC15,SKAP1,GPR137C,FGR,OR2T33,PLXDC2,CLDN12,SVIL,GRIN2D,TNFRSF17,CERS1,B4GALT7,OCLN,SLC43A1,ATP1A3,MPZL3,UGT8,ACSL1,SLC2A13,CACNB4,ABHD4,DNER,KREMEN1,HMCN1,SLCO3A1,CHST10,FKBP11,F3,RTN1,CYP51A1,EPCAM,SLC10A7,CNNM2,TRPC1,HRK,SLC2A12,CTTN,EPHB6,OR2W3,PTPRE,GALNT18,IL1RAP,PDGFRB,RASGRP1,LAMP3,CYP1B1,ATL1,TNK2,GPM6A,CEMIP2,JPH1,TMEM47,ROR1,TMEM132B,TMEM150B,GPRC5B,HPSE,NCAM2,OXTR,TNFSF4,FNDC10,SLC9B1,FRMD5,PCSK5,GPR63,UST,SV2B,FN1,SEC24D,BVES,SCART1,STXBP6,ELOVL7,CYP4V2,ATP6V1E2,GALNT13,SCD,CHSY1,CD7,SPINK5,ADGRG6,PCDHB14,EEF2,CA2,SLC30A4,VSIR,NCEH1,RNF148,LRP3,NOS3,SNX7,ATP5IF1,PCDH10,CDH26,IL17RD,GPR176,RHOQ,PODXL2,SLITRK2,PARD3B,SDC3,WWC1,GALNT17,CATSPERE,B4GALNT3,SLC46A3,STEAP1,HERPUD1,GLCE,TMEM154,RIPOR2,ADGRB3,FCHO2,FAT1,NCR3LG1,SH3BP4,TMEM117,PTPRN2,DISP2,OSBPL6,XKR4,DIRC2,CREB3L2,CXCR5,SORBS1,IL15,CELSR3,CANX,CD53,UNC13B,PDZD8,ERO1B,REEP1,MAP7,ACVR2A,STEAP3,PROS1,MET,TMEM120B,HSPA2,NTNG1,SEMA6C,ALG10B,DPP10,SUSD3,FER,ANTXR2,PTPRU,SLC39A8,PTPN6,C3orf52,AMIGO1,SYNJ2BP,CD40,CAMK2N1,TMPRSS9,CYP2U1,RNF130,DISP1,LIFR,OR51B5,TNIK,CLGN,TSPAN15,CMTM8,LRP4,TNFSF13B,CLSTN2,FAM174B,SEL1L3,MCU,FSD1,KCNJ4,SCN1B,LHFPL6,DSG2,EHD3,KIAA0319,MARCH3,IQGAP3,TNFRSF11A,TESPA1,RAB3B,CRIM1,CYTH3,SYBU,GRID1,PRRG1,ARHGAP32,GALNT14,TLR6,NAALADL2,LRAT,LEPR,DPY19L2,GPR37,MYADM,EDA,MFSD9,MPP7,ACER2,CTSV,THSD7B,SLC7A5,SLC18B1,GEM,MMP16,IL9R,SLC16A10,ABCG1,SNPH,STOM |
| 1.239e-13 | -29.72 | lung-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-adenocarcinoma | 15601 | 1605 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,TSC22D1,SGK1,TSPAN13,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,CD37,DOCK7,FBN1,SH3BGRL2,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,CTTNBP2,NR3C2,KCTD1,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,TTLL7,DOCK5,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 1.317e-13 | -29.66 | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | 59 | 28 | 17377 | 1707 |
GPT2,GPR63,PCDH18,SESN2,DCC,KLHL4,ALDH1L2,VLDLR,ASS1,KIF21B,PHGDH,TBC1D16,MAP1B,WARS,CEBPB,GALNT3,TRIB3,ASNS,SLC7A11,EIF4EBP1,STC2,SLC7A5,ADRB1,RAB31,INHBE,HS3ST3B1,PCK2,STOM |
| 1.341e-13 | -29.64 | diffuse_adenocarcinoma | COSMIC cancer mutations | diffuse_adenocarcinoma | 4468 | 565 | 17385 | 1698 |
ARHGAP26,THOC5,DNAJC3,NPM1,STAT5B,CTBP2,CADM2,DOCK3,KIAA1217,SNX9,EYA4,PCDH7,EPDR1,TGFBR3,DNAH6,PPFIA2,RAP2A,TSHR,MEIS2,SMAD9,DCC,KLHL23,DSTN,LRRK2,ELMOD1,PRKAR2B,KCND3,ZNF266,WIPF3,ATP7B,MAP9,ARHGAP28,ERCC5,DNHD1,VASH2,C12orf77,SCN5A,TJP1,GPSM2,BBS9,SYCP2,FRY,BACE2,APLF,FAM189A1,ZIC5,SRGAP1,CADPS2,ALPK1,NCAM1,JAM2,AGL,STXBP1,LRP12,FADS1,KCNQ3,STAT4,EFHC2,FASN,FHL2,RYR2,ST6GALNAC3,ZBBX,TAF4B,MBNL2,DHX32,CACHD1,TEX15,TMCO3,ADAMTS3,CLMN,TRPC3,CDH2,DOCK9,TFCP2L1,DNM3,ZNF516,BEGAIN,RGS20,ADD2,IL13RA1,COLEC10,TXNRD3,CDS1,EPB41L3,COL25A1,DACT1,MAGEA3,ALDH1L1,DNAH5,SNX10,MYT1,KCNB2,SCN3A,DOCK8,C3orf67,DZANK1,COL6A2,RNF145,PFKFB2,KCNH5,TTC28,DSP,FGFR1,PDLIM3,WWTR1,LAMB1,PLEKHG1,FARP1,ANKRD13B,WDR17,ROBO2,CKAP2,UBAC2,NKAIN2,PSD3,CBS,P2RY1,CREB5,PKN1,EPHB1,COL27A1,NEO1,PCBP4,GAS2L3,NPTXR,C15orf41,MED12L,PARP9,TRPM4,MCF2L2,RAPGEF2,RASA3,ATP11A,SNTB1,HEG1,PTPRC,NSD1,PLOD2,PLPPR2,AKT3,HK1,DOCK6,DCBLD1,CRISPLD1,TLL2,TRIM2,CACNG3,FGF13,FHDC1,NRN1,NUP62CL,FSTL5,CCNJ,PLS3,ANKRD42,RUFY4,CPNE2,TM9SF2,KCNAB1,AADAT,KCNN2,ITGB3,COL19A1,KIAA1614,TMEM132E,TLN2,ENO1,ETV1,NEB,MARK1,COL4A3,SPOCD1,ANK2,NFE2L1,TCERG1L,CRYBG3,TSKU,SPNS1,INSIG1,MAP2,GNB4,TECPR2,PIK3C2B,HS6ST3,STXBP5L,ITPRIP,SETBP1,SORBS3,PGAP1,FHOD3,HSPA12B,PRTFDC1,ZBTB38,IGF1R,ABCA5,BCHE,FRAS1,PDE10A,HS3ST5,SMTN,LRP6,ADCY6,SLCO4C1,DPYSL5,CHSY3,MGAT4B,GPSM1,WDR25,OBSCN,SDK1,KHDRBS2,TEX9,GRIK4,ATPAF2,HEYL,CSF1,MFSD2A,PLD1,SEMA3A,MME,ID1,CFH,DOCK1,XYLT1,NTRK3,LPIN3,KIF21B,DENND3,KBTBD11,TNKS1BP1,RADIL,SEMA6A,PCLO,TBC1D19,FAM131B,SLC22A17,TACC2,MYO3B,ZDHHC23,MYH15,SCN2A,CTH,GLI1,THSD4,PRDM13,CHRNA6,VIM,SMAD3,NRG3,PTPRJ,ANKRD31,PTK7,GBP1,ITGA2,MAOA,HGF,CTNND2,CNTN1,TENM1,COL9A3,DYRK3,SLC6A9,NECAB2,IL32,GRB14,MCTP2,ARHGAP44,PPP2R3A,SLC35F1,FOXP2,PRICKLE2,KIAA0408,SH3PXD2B,KIAA1211,ATP2B1,CES3,DLGAP1,MICAL2,LRRIQ1,PRICKLE1,FERMT2,FNDC3A,ILDR2,EBF1,FAT4,FBN1,L3MBTL4,ZNF808,DLG2,ZNF474,SLC22A15,PAX9,SLC1A5,TBC1D4,PKIA,CACNA2D1,FILIP1,ZNF235,PAGE1,PPP4R4,TCP11L2,ATP8A1,PPFIBP2,DACH2,TRPS1,SLC22A18,KCNS3,CHRDL1,ATRNL1,BEND4,THSD1,TBC1D8,EML6,KLHL3,DNAJC6,DEPTOR,TNS1,ZDHHC14,AHRR,NCKAP1L,ENPP6,RASGRF2,BMP1,DSEL,UNC5B,EFNB2,LRFN5,INPPL1,CELSR1,FAM124A,PTPRD,OLAH,OPHN1,WDFY4,SLC1A3,DYNC1I1,MTUS1,MECOM,ABLIM1,NAV1,CNTN4,SLC7A11,NOVA2,PDZD7,VWDE,PRKG1,RUNDC3B,CPXM2,GRIP1,TSPAN12,MPDZ,COL9A2,GPR161,RIMS2,IGSF3,EPB41L5,PTCH2,DCHS1,VLDLR,TTYH2,PEX5L,CCDC85A,DAGLA,PLEKHH2,PKN3,CECR2,THBS4,LRRIQ3,DYNC2LI1,SQLE,DHCR7,SMYD3,FRMPD3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,ST14,OTX1,MSR1,SPATS2L,COL14A1,TIAM2,ZNF827,SPEG,NELL2,ASNS,ZNF438,NBEA,NAP1L3,SERPINH1,TRDMT1,VNN2,PREX1,NLGN4X,SATB2,ISG20,ZNF711,HTR7,PRKCB,CCNA1,NR3C2,MID1,COBL,MYO1D,PLSCR4,MXI1,ATP9A,EPS8,CCNJL,HERC5,RGS7,SOAT2,AFF2,RALGAPA2,DYNC2H1,TBC1D9,SLC40A1,ARAP2,SYNPO2,MPP1,PTPN13,CACNA1E,RPL21,GUCY1A2,GPR137C,ZIC1,TERT,CLDN12,PLXDC2,MCC,TUFT1,SVIL,CERS1,OCLN,EXPH5,ACSL1,MVK,KIF5A,ACTL8,PTPN21,ABAT,SLC2A13,DNER,CACNB4,HMCN1,CYP51A1,SIPA1L2,LRRC6,DLX6,ANKFN1,SLC2A12,PCOLCE2,PTPRE,FANK1,MYRIP,SLIT2,IL1RAP,PDGFRB,GPM6A,JPH1,RNF44,EML1,TMEM132B,NCAM2,NCOA7,MAGI2,UST,BCL11B,GPR63,MOCOS,FN1,ZNF395,BVES,SCART1,RIMKLA,LAMC3,GALNT13,CHSY1,PHGDH,SPINK5,EEF2,LIMCH1,BARX1,LRP3,CAND2,NOS3,PCDH10,SLITRK2,SH2D2A,WWC1,SDC3,LHPP,AMDHD1,HERPUD1,KIAA0355,FAT1,PTPRN2,XKR4,DMXL2,EML5,CELSR3,PLEKHA5,ARHGAP22,COBLL1,COL18A1,TDRKH,BCL6B,DOCK2,COL22A1,KCTD15,UNC13B,KAZN,PPFIBP1,ZNF521,MAP7,ACVR2A,MET,NTNG1,DPP10,FER,PTPRU,SLC39A8,DOCK5,TTLL7,ZNF569,ARMC4,MAGEA12,LMLN,TRIM34,BACH2,DUSP19,DISP1,LIFR,MAST1,ARHGEF11,REL,CLSTN2,COL4A5,SYDE2,CHN2,TRIM3,CCDC122,DHRS12,IPCEF1,IQGAP3,RRAS2,GRID1,MARS,PHACTR2,CCNG1,ZFPM2,LEPR,CTIF,MAP1B,GPR37,ADAMTS17,SUGT1,ICA1,RND3,THSD7B,KIF21A,NPHP1,MMP16 |
| 1.341e-13 | -29.64 | stomach-carcinoma-diffuse_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-diffuse_adenocarcinoma | 4468 | 565 | 17385 | 1698 |
ARHGAP26,THOC5,DNAJC3,NPM1,STAT5B,CTBP2,CADM2,DOCK3,KIAA1217,SNX9,EYA4,PCDH7,EPDR1,TGFBR3,DNAH6,PPFIA2,RAP2A,TSHR,MEIS2,SMAD9,DCC,KLHL23,DSTN,LRRK2,ELMOD1,PRKAR2B,KCND3,ZNF266,WIPF3,ATP7B,MAP9,ARHGAP28,ERCC5,DNHD1,VASH2,C12orf77,SCN5A,TJP1,GPSM2,BBS9,SYCP2,FRY,BACE2,APLF,FAM189A1,ZIC5,SRGAP1,CADPS2,ALPK1,NCAM1,JAM2,AGL,STXBP1,LRP12,FADS1,KCNQ3,STAT4,EFHC2,FASN,FHL2,RYR2,ST6GALNAC3,ZBBX,TAF4B,MBNL2,DHX32,CACHD1,TEX15,TMCO3,ADAMTS3,CLMN,TRPC3,CDH2,DOCK9,TFCP2L1,DNM3,ZNF516,BEGAIN,RGS20,ADD2,IL13RA1,COLEC10,TXNRD3,CDS1,EPB41L3,COL25A1,DACT1,MAGEA3,ALDH1L1,DNAH5,SNX10,MYT1,KCNB2,SCN3A,DOCK8,C3orf67,DZANK1,COL6A2,RNF145,PFKFB2,KCNH5,TTC28,DSP,FGFR1,PDLIM3,WWTR1,LAMB1,PLEKHG1,FARP1,ANKRD13B,WDR17,ROBO2,CKAP2,UBAC2,NKAIN2,PSD3,CBS,P2RY1,CREB5,PKN1,EPHB1,COL27A1,NEO1,PCBP4,GAS2L3,NPTXR,C15orf41,MED12L,PARP9,TRPM4,MCF2L2,RAPGEF2,RASA3,ATP11A,SNTB1,HEG1,PTPRC,NSD1,PLOD2,PLPPR2,AKT3,HK1,DOCK6,DCBLD1,CRISPLD1,TLL2,TRIM2,CACNG3,FGF13,FHDC1,NRN1,NUP62CL,FSTL5,CCNJ,PLS3,ANKRD42,RUFY4,CPNE2,TM9SF2,KCNAB1,AADAT,KCNN2,ITGB3,COL19A1,KIAA1614,TMEM132E,TLN2,ENO1,ETV1,NEB,MARK1,COL4A3,SPOCD1,ANK2,NFE2L1,TCERG1L,CRYBG3,TSKU,SPNS1,INSIG1,MAP2,GNB4,TECPR2,PIK3C2B,HS6ST3,STXBP5L,ITPRIP,SETBP1,SORBS3,PGAP1,FHOD3,HSPA12B,PRTFDC1,ZBTB38,IGF1R,ABCA5,BCHE,FRAS1,PDE10A,HS3ST5,SMTN,LRP6,ADCY6,SLCO4C1,DPYSL5,CHSY3,MGAT4B,GPSM1,WDR25,OBSCN,SDK1,KHDRBS2,TEX9,GRIK4,ATPAF2,HEYL,CSF1,MFSD2A,PLD1,SEMA3A,MME,ID1,CFH,DOCK1,XYLT1,NTRK3,LPIN3,KIF21B,DENND3,KBTBD11,TNKS1BP1,RADIL,SEMA6A,PCLO,TBC1D19,FAM131B,SLC22A17,TACC2,MYO3B,ZDHHC23,MYH15,SCN2A,CTH,GLI1,THSD4,PRDM13,CHRNA6,VIM,SMAD3,NRG3,PTPRJ,ANKRD31,PTK7,GBP1,ITGA2,MAOA,HGF,CTNND2,CNTN1,TENM1,COL9A3,DYRK3,SLC6A9,NECAB2,IL32,GRB14,MCTP2,ARHGAP44,PPP2R3A,SLC35F1,FOXP2,PRICKLE2,KIAA0408,SH3PXD2B,KIAA1211,ATP2B1,CES3,DLGAP1,MICAL2,LRRIQ1,PRICKLE1,FERMT2,FNDC3A,ILDR2,EBF1,FAT4,FBN1,L3MBTL4,ZNF808,DLG2,ZNF474,SLC22A15,PAX9,SLC1A5,TBC1D4,PKIA,CACNA2D1,FILIP1,ZNF235,PAGE1,PPP4R4,TCP11L2,ATP8A1,PPFIBP2,DACH2,TRPS1,SLC22A18,KCNS3,CHRDL1,ATRNL1,BEND4,THSD1,TBC1D8,EML6,KLHL3,DNAJC6,DEPTOR,TNS1,ZDHHC14,AHRR,NCKAP1L,ENPP6,RASGRF2,BMP1,DSEL,UNC5B,EFNB2,LRFN5,INPPL1,CELSR1,FAM124A,PTPRD,OLAH,OPHN1,WDFY4,SLC1A3,DYNC1I1,MTUS1,MECOM,ABLIM1,NAV1,CNTN4,SLC7A11,NOVA2,PDZD7,VWDE,PRKG1,RUNDC3B,CPXM2,GRIP1,TSPAN12,MPDZ,COL9A2,GPR161,RIMS2,IGSF3,EPB41L5,PTCH2,DCHS1,VLDLR,TTYH2,PEX5L,CCDC85A,DAGLA,PLEKHH2,PKN3,CECR2,THBS4,LRRIQ3,DYNC2LI1,SQLE,DHCR7,SMYD3,FRMPD3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,ST14,OTX1,MSR1,SPATS2L,COL14A1,TIAM2,ZNF827,SPEG,NELL2,ASNS,ZNF438,NBEA,NAP1L3,SERPINH1,TRDMT1,VNN2,PREX1,NLGN4X,SATB2,ISG20,ZNF711,HTR7,PRKCB,CCNA1,NR3C2,MID1,COBL,MYO1D,PLSCR4,MXI1,ATP9A,EPS8,CCNJL,HERC5,RGS7,SOAT2,AFF2,RALGAPA2,DYNC2H1,TBC1D9,SLC40A1,ARAP2,SYNPO2,MPP1,PTPN13,CACNA1E,RPL21,GUCY1A2,GPR137C,ZIC1,TERT,CLDN12,PLXDC2,MCC,TUFT1,SVIL,CERS1,OCLN,EXPH5,ACSL1,MVK,KIF5A,ACTL8,PTPN21,ABAT,SLC2A13,DNER,CACNB4,HMCN1,CYP51A1,SIPA1L2,LRRC6,DLX6,ANKFN1,SLC2A12,PCOLCE2,PTPRE,FANK1,MYRIP,SLIT2,IL1RAP,PDGFRB,GPM6A,JPH1,RNF44,EML1,TMEM132B,NCAM2,NCOA7,MAGI2,UST,BCL11B,GPR63,MOCOS,FN1,ZNF395,BVES,SCART1,RIMKLA,LAMC3,GALNT13,CHSY1,PHGDH,SPINK5,EEF2,LIMCH1,BARX1,LRP3,CAND2,NOS3,PCDH10,SLITRK2,SH2D2A,WWC1,SDC3,LHPP,AMDHD1,HERPUD1,KIAA0355,FAT1,PTPRN2,XKR4,DMXL2,EML5,CELSR3,PLEKHA5,ARHGAP22,COBLL1,COL18A1,TDRKH,BCL6B,DOCK2,COL22A1,KCTD15,UNC13B,KAZN,PPFIBP1,ZNF521,MAP7,ACVR2A,MET,NTNG1,DPP10,FER,PTPRU,SLC39A8,DOCK5,TTLL7,ZNF569,ARMC4,MAGEA12,LMLN,TRIM34,BACH2,DUSP19,DISP1,LIFR,MAST1,ARHGEF11,REL,CLSTN2,COL4A5,SYDE2,CHN2,TRIM3,CCDC122,DHRS12,IPCEF1,IQGAP3,RRAS2,GRID1,MARS,PHACTR2,CCNG1,ZFPM2,LEPR,CTIF,MAP1B,GPR37,ADAMTS17,SUGT1,ICA1,RND3,THSD7B,KIF21A,NPHP1,MMP16 |
| 1.402e-13 | -29.60 | lung-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-small_cell_carcinoma | 10147 | 1131 | 17385 | 1698 |
ARHGAP26,THOC5,GRIK2,CNTNAP3,TUBE1,NPM1,CEBPA,BCAN,KIAA1217,SNX9,SKI,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,FGF17,INTS6,ENPP1,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,TPM1,DNHD1,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,SRGAP1,TOX,CADPS2,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,EFHC2,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SNAP25,ZBBX,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,CLMN,HOXD13,CDH2,DOCK9,ADD2,GRK6,TLR3,FAM133A,DNAH5,ZNF365,MYT1,SNX10,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,PFKFB2,ADCY1,WNT11,ASPH,MAGI3,GJC1,CXCL10,ARHGAP21,PDLIM3,LAMB1,RAB30,ANKRD13B,WDR17,GCAT,FZD8,CD276,PLAG1,BIK,CBS,SLC12A6,GAS6,EPHB1,BEX2,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,PIP5KL1,BMP4,ATP2B4,CRISPLD1,TLL2,PHACTR3,CACNG3,FGF13,TRIM16,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RPS6KA2,CPVL,SEC16B,ITGB3,TMEM143,MPPED2,ENO1,RAPGEF5,DBN1,MARK1,PNRC1,COL4A3,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,DYRK1B,TRIM9,TCF7L1,KCNMB4,ERN1,HS6ST3,RRAGD,KCNV1,RUNX2,STXBP5L,SORBS3,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,GAN,HS3ST5,LRP6,ADCY6,FAR2,DPYSL5,MGAT4B,GPSM1,STRADB,MAFB,OBSCN,SLITRK5,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,DDX60L,TACC2,BCL6,EEPD1,MYH15,IGFBP3,INTU,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,USP30,SLC35F1,FOXP2,SGK1,KIAA0408,SYK,ATP2B1,DUSP1,LRRIQ1,FOXN3,CRIP2,PALLD,ILDR2,MGMT,SMPDL3B,DKK1,EBF1,DOCK7,FBN1,SH3BGRL2,PTGES,CACNA2D1,ZNF235,FAM171B,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,KCNS3,GLDC,ERGIC1,ACVR1C,WISP3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,BMP1,MAPK13,SERPINI1,DSEL,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,ST6GAL1,MLF1,LRRC49,APBA1,TNFRSF19,GAS1,ABLIM1,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,CPXM2,GRIP1,FAM155A,PRR16,GPR161,BOD1,PTCH2,DISC1,RPL26,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,THBS4,LRRIQ3,MPP2,DYNC2LI1,SQLE,DHCR7,SLFN5,SMYD3,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ZNF438,ALDOC,PDE4D,GAB2,TRDMT1,B3GALT1,SHANK2,PREX1,NLGN4X,SATB2,ATF3,ATOH1,PYGO1,ATP10D,ISG20,ZNF711,IKZF3,CCNA1,BMPR1A,COBL,STON2,MID1,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,RASSF8,LRRC55,AFF2,GPR155,TBC1D9,SMAD6,TMC7,VAV3,SLC40A1,ALDH2,SH3BP2,PXN,PTPN13,ZDHHC15,UCHL3,HOXA1,MCC,SVIL,TNFRSF17,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,PPM1E,SIPA1L2,ANKFN1,CNNM2,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GPRC5B,HPSE,TNFSF4,PPARGC1A,MAGI2,PCSK5,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,FBXO4,CHADL,CHSY1,SPINK5,PCDHB14,RNF141,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,PCDH10,HBG2,RHOQ,SLITRK2,SDC3,STEAP1,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COBLL1,CANX,CD53,PDZD8,CDC14B,PPFIBP1,C12orf60,FABP6,ACVR2A,FHIT,PROS1,NTNG1,SEMA6C,ALG10B,PRAME,PTPRU,PTPN6,MVD,TCEAL3,CD40,BCL11A,ZNF569,ARMC4,MAGEA12,KPNA3,TRIM34,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,SSX1,TNFSF13B,IGF2BP2,COL4A5,OVOL2,BMP6,MCU,RAB11FIP5,KCNJ4,PRKCD,STC2,AFAP1L2,RBMS2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,IL9R,ABCG1,GXYLT2,PDE1B,PRSS12,AASS,DNAJC3,CADM2,STAT5B,DOCK3,CA8,NOS1AP,EYA4,EPDR1,PCDH7,BAG3,FBXO32,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,CAP2,TGFA,CA13,ZNF266,ALDOA,ARHGAP28,TMEFF2,MEF2C,LPP,CARS,LATS2,GNG12,STOX2,CYP2J2,SYCP2,RSL24D1,BNIP1,KIAA1671,FAM189A1,BACE2,ZIC5,LOXL4,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,CHRM3,HMGCR,PNP,MYO10,STAT4,CALCRL,SMARCD3,RYR2,PLS1,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,BTC,DNM3,TMSB15A,GALNT12,LRRCC1,RGS20,PKP2,IL13RA1,NRXN1,COLEC10,TXNRD3,EPB41L3,RNF150,GPRIN1,DACT1,RTKN2,PJA1,RAB27B,ARL4D,FAM155B,SCN3A,DOCK8,PERP,DZANK1,GARS,RNF145,FZD4,KCNH5,RAB38,FGFR1,IRS2,IQCK,IQCH,GYPC,INPP4B,PAM,ALG11,P4HA1,TNFSF15,PLD5,C2orf88,FARP1,EDA2R,ROBO2,C1QTNF3,IPO5,NKAIN2,CREB5,P2RY1,PKN1,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,NPTXR,MYO6,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,SNTB1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,BTRC,FOXA1,DCBLD1,TPT1,NBPF4,TRIM2,SYT12,FHDC1,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,EOMES,HPS1,MARVELD2,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,ABCC4,PLEKHA1,BATF,NT5DC2,PLEKHB1,TSKU,MAP2,P4HA2,GNB4,CCDC146,TECPR2,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,RASL11B,SETBP1,MLC1,PGAP1,IL18R1,HSPA12B,KIAA0895,IGF1R,ABCA5,GATA2,BCHE,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,SLC27A2,SPATA13,TMTC4,PPFIA4,WDR25,TEX9,MAPKAPK2,NAP1L5,HEYL,SFN,MME,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,FAM198B,LPIN3,SEZ6L2,PCLO,CYP26A1,FAM131B,SLC22A17,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,TMEM67,UROS,THSD4,FGF12,FBXO36,PAGE5,FRK,JAM3,SMAD3,RANBP2,NRG3,PTK7,KCNG1,ITGA2,SEPT5,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,GRB14,RUSC2,NLRP14,BLVRB,HBE1,PPP2R3A,MAP1A,RASD2,EIF1,SH3PXD2B,PCK2,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,ZNF808,PAX9,TBC1D4,FILIP1,CGN,MYCBP2,PAGE1,ACVR1,LANCL3,SIDT1,DUSP8,PPFIBP2,GATA3,ADAMTS6,DACH2,RAC3,STK24,CFHR1,FAM168A,SLC16A2,CHRDL1,ATRNL1,SP140,VWA5A,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,TNS1,ACVR2B,SAV1,AHRR,SFXN1,HLF,NCKAP1L,PLK2,RASGRF2,UNC5B,TANC2,LZTS1,INPPL1,EHHADH,CELSR1,ALOX5AP,ZHX3,PTPRD,SCN8A,OPHN1,SLC25A27,GTF2IRD1,WDFY4,TNFRSF10C,DYNC1I1,ADSSL1,CHD5,PRRG4,MECOM,MCOLN2,NAV1,CNTN4,PIK3AP1,RUNDC3B,TSPAN12,MPDZ,SAMD13,RIMS2,RNF152,IGSF3,QSOX1,PLEKHA8,TBC1D8B,COL4A4,KIAA1324L,TTYH2,PLCB1,ZNF558,FAM162A,DAGLA,PKN3,PMEPA1,IQSEC2,AMPD1,ACSM3,PLA2G4A,EPHA3,FRMPD3,PCSK1N,RASAL2,ELOVL4,RNF144A,GPR65,CHUK,NUDT12,TBC1D30,ZNF827,NELL2,STARD4,DAB2IP,NAP1L3,SERPINH1,VNN2,PDK1,TMEM43,PNMA6A,PRKCQ,TBC1D16,HTR7,PRKCB,GRB10,CTTNBP2,NR3C2,WASF3,MXI1,ATP9A,ARL2,GPR180,RGS7,GDPD5,NEDD4,RGS17,SGK3,RALGAPA2,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,ARAP2,SYNPO2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,MYOM2,ATP1A3,SLC43A1,EXPH5,MVK,KIF5A,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,KREMEN1,QPRT,FKBP11,ARHGEF10L,RTN1,AKAP7,DLX6,POF1B,SLC2A12,HRK,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,GPM6A,CAPN5,ROR1,RNF44,SERGEF,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,BCL11B,FN1,SEC24D,JDP2,ELOVL7,CYP4V2,LAMC3,ATP6V1E2,GALNT13,SATB1,DDIT4,OTUD1,CA2,EBF4,NOS3,IL17RD,GPR176,MSTN,PARD3B,EDEM3,DUSP9,WWC1,PRDM1,RAI14,HK2,EGFL7,DIRC2,CREB3L2,CXCR5,NEK10,ZSWIM5,CELSR3,PLEKHA5,MORC4,TDRKH,BCL6B,DOCK2,ZSCAN5A,COL22A1,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,POU2F2,MET,WWC2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,TTLL7,C1orf174,TPK1,MSC,LMLN,BACH2,DISP1,LIFR,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,CLSTN2,NOTUM,RPL34,CHN2,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,RAB3B,ESRRG,NR4A1,CYTH3,GRID1,OGDHL,PRRG1,MARS,PHACTR2,AGAP2,CCNG1,ARHGAP32,ZFPM2,C3orf70,RERE,MAP1B,GPR37,ADAMTS17,NACC2,MPP7,MAP2K6,THSD7B,SLC7A5,KIF21A,GEM,MMP16,SLC16A10,SNPH |
| 1.773e-13 | -29.36 | cell migration | biological process | GO:0016477 | 852 | 149 | 17256 | 1658 |
ACVR1,FGF13,JCHAIN,GATA3,STAT5B,DNER,RAC3,EPCAM,RND2,TGFBR3,ITGB3,CTTN,SLIT2,POU3F3,PDGFRB,NKX2-1,CYP1B1,TNK2,ITGB7,GPM6A,SLC3A2,MARK1,DCC,LRRK2,EFHC1,TNS1,GPC6,NCKAP1L,SEMA3C,PIK3C2B,NRP1,TMEFF2,MEF2C,BCL11B,EFNB2,TYRO3,FN1,CELSR1,LGALS3,BVES,ITGA6,OPHN1,FOXG1,DDIT4,MCOLN2,NAV1,SLC7A11,SEMA4F,GATA2,FLRT3,PRKG1,JAM2,LRP12,NOS3,EPB41L5,PAK1,FGFR4,DISC1,PODXL2,RHOQ,ARID5B,DCHS1,SPATA13,SDC3,WWC1,CDC42BPA,PKN3,THBS4,FAT1,MATN2,CDH2,SEMA3A,SIX2,SHTN1,EPHA3,CXCR5,ID1,AMOTL1,RHOD,DOCK1,CELSR3,RBFOX2,PSTPIP2,PLXNA2,ADD2,NTRK3,DDR1,CTNNA2,GPR15,PLPP1,LHX6,DAB2IP,PROS1,PDE4D,SNAI2,DOCK8,FER,PTPN6,PREX1,PRKCQ,WNT11,SATB2,ATOH1,ATP1B1,FRK,JAM3,CENPV,FGFR1,CXCL10,NRG3,GYPC,APELA,PTK7,LAMB1,ITGA2,HGF,HOXB9,PAK5,GRB14,EPS8,SELL,GAS6,OVOL2,P2RY1,PKN1,EPHB1,NKX6-1,PRKCD,KIAA0319,TNFRSF11A,SYK,FES,PARP9,VEGFC,TRPM4,VAV3,PXN,RAPGEF2,NR4A1,ASAP3,PALLD,PEAK1,GPLD1,RERE,MAP1B,PTPRC,FGR,RND3,SLC7A5 |
| 2.889e-13 | -28.87 | pancreas-carcinoma | COSMIC cancer mutations | pancreas-carcinoma | 15226 | 1575 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,ATF4,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,TMEM200C,CR2,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,KAZN,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RNF157,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,FAM155B,ARL4D,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,PCLO,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,HBE1,PPP2R3A,ARHGAP44,TECPR1,MAP1A,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,WASF3,ANO10,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,BARX1,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 2.935e-13 | -28.86 | cell differentiation | biological process | GO:0030154 | 3578 | 461 | 17256 | 1658 |
THOC5,ACVR1,PDE1B,LGR4,LDLR,MCOLN3,GATA3,ENAH,CTBP2,CEBPA,STAT5B,CHAC1,PRKCA,RAC3,STK24,NCS1,EYA4,TRPS1,SKI,TYMP,TGFBR3,RAP2A,CHRDL1,GSTM3,PACSIN1,POU3F3,NKX2-1,SLC9C1,ACVR1C,DCC,LRRK2,FEZ1,ACVR2B,SAV1,ARHGEF26,SFXN1,SPATA9,HLF,NCKAP1L,WIPF3,PLK2,BDH2,BMP1,ADRB1,SEMA3C,SERPINI1,TMOD2,INPP5F,UNC5B,NRP1,TPM1,SPART,MEF2C,EFNB2,LRFN5,SEMA6B,MRC2,CELSR1,ZHX3,PTPRD,GABRB2,MLF1,ITGA6,OPHN1,TJP1,SLC1A3,HERC6,FOXG1,BBS9,CHD5,GAS1,MYORG,MECOM,CHN1,NAV1,CNTN4,SLC7A11,FRY,PDZD7,FLRT3,ZIC5,SREBF1,PRKG1,GRIP1,TOX,NCAM1,STXBP1,GFRA1,RIMS2,LRP12,ZNF385A,HMGCR,PTCH2,EPB41L5,ENAM,BDNF,DISC1,SPATA6,VLDLR,ARID5B,DCHS1,FHL2,FASN,SMARCD3,HIP1,SNAP25,TAF4B,PLCB1,CLN5,DAGLA,MMP15,TEX15,SH3GL2,MATN2,INHBE,CDH17,CLMN,SFMBT1,SLFN5,DHCR7,CDH2,SMYD3,CSRP2,SHTN1,EPHA3,TFCP2L1,NBL1,DNM3,ZNF516,ST14,PLXNA2,PKP2,CHUK,NRXN1,DDR1,TXNRD3,EPB41L3,SPEG,GPRIN1,COL25A1,ALDOC,DAB2IP,PDE4D,SERPINH1,SNX10,ZNF365,MYT1,PERP,GAB2,FZD1,SSH3,MYLK3,FZD4,NKX3-2,SOX21,SHANK2,PREX1,ADCY1,NLGN4X,SATB2,PRKCQ,WNT11,CBY1,ATF3,RAB38,PYGO1,ATOH1,DSP,FGFR1,GJC1,IRS2,POPDC3,APELA,LAMB1,WWTR1,MAP3K21,KLF5,GRB10,BMPR1A,ATG5,MAPK10,STON2,COBL,WASF3,FARP1,C1QTNF3,EDA2R,ROBO2,PLAG1,FZD8,KIF5C,GAS6,P2RY1,EPHB1,GDPD5,NEDD4,COL27A1,NEO1,HOPX,LRRC55,IRX5,SOAT2,LRRN1,BHLHA15,MORN2,DYNC2H1,FIG4,NPTXR,GFI1,SMAD6,SPRY2,ZFP36L2,FES,B9D1,VEGFC,PDLIM7,LZTS3,ARHGEF28,RAPGEF2,GPLD1,ZIC1,HEG1,CEBPB,PTPRC,ID3,FGR,TERT,GNAO1,XBP1,MYOM2,BMP4,LRRK1,SHOX2,FOXA1,TPT1,TLL2,EXPH5,UGT8,FGF13,KIF5A,ACTL8,LILRB1,HDGFL3,NDRG2,DNER,RBM11,GSDME,RND2,EPCAM,EOMES,KCNAB1,DLX6,MARVELD2,ITGB3,POF1B,COL19A1,CTTN,EPHB6,ETV1,IL1RAP,SLIT2,RASGRP1,PDGFRB,DBN1,ATL1,TNK2,ITGB7,GPM6A,MARK1,ATF4,ANK2,NFE2L1,YAP1,CR2,PLEKHA1,ROR1,BATF,EML1,TSKU,DYRK1B,INHBC,GSN,TCF7L1,GPRC5B,NCAM2,MAP2,AHNAK2,DLX2,PPARGC1A,MAGI2,NEUROG2,UST,BCL11B,TYRO3,RUNX2,FN1,LGALS3,BVES,LAMC3,ZIC2,CHSY1,PHGDH,SPINK5,SATB1,ADGRG6,IL18R1,DOK5,FHOD3,DDIT4,NUMBL,IGF1R,SEMA4F,EEF2,BCHE,GATA2,ADCY6,LRP6,BNIP3,SLCO4C1,BARX1,FGFR4,DPYSL5,PAK1,ATP5IF1,UNC5C,SLITRK2,MSTN,SH2D2A,EFNA3,GPSM1,MAFB,OBSCN,SLITRK5,PRDM1,SDK1,BAIAP2,NEGR1,ADGRB3,PLAGL1,RIPOR2,MFSD2A,HEYL,CSF1,RAI14,EGFL7,SEMA3A,NKX2-8,TESC,SFN,SIX2,CREB3L2,PRKN,ZSWIM5,ID1,CELSR3,IL15,RBFOX2,ARHGAP22,COL18A1,HECW2,NTRK3,TDRKH,RADIL,DOCK2,PPP1R9A,CBLN1,SEMA6A,CTNNA2,KAZN,LHX6,BCL6,ZNF521,POU2F2,MET,ZNF488,TMEM120B,HSPA2,NTNG1,SEMA6C,SNAI2,GLI1,IGFBP3,INTU,PRAME,FER,EVL,PTPRU,PTPN6,PRDM13,VIM,AMIGO1,RARRES2,FRK,TTLL7,JAM3,BATF3,BCL11A,SMAD3,NRG3,PTK7,ITGA2,PTPRS,SOHLH2,HGF,CTNND2,HEY1,CNTN1,TENM1,TNIK,DYRK3,BMPR2,LRP4,NLRP14,APBB1,PRDM8,OVOL2,BMP6,ARHGAP44,NKX6-1,FOXP2,MAP1A,SCN1B,GTSF1,DSG2,KIAA0319,ACTA2,SGK1,SH3PXD2B,PCK2,RRAS2,TNFRSF11A,SYK,SLC45A3,PCSK6,MSX1,KDM5B,NR4A1,FOXN3,MEI1,FERMT2,ZFPM2,PALLD,FNDC3A,PEAK1,ILDR2,LEPR,MGMT,MAP1B,DKK1,RERE,DPY19L2,DOCK7,MYADM,FAT4,EDA,CTSV,SLC7A5,MYRF,MAP3K20,NPHP1,SNPH |
| 4.052e-13 | -28.53 | cell morphogenesis involved in differentiation | biological process | GO:0000904 | 524 | 104 | 17256 | 1658 |
ID1,CELSR3,ST14,KIF5A,RBFOX2,PLXNA2,COL18A1,GATA3,ENAH,PRKCA,NRXN1,RADIL,SEMA6A,CTNNA2,COL25A1,ITGB3,POF1B,MET,ETV1,ZNF365,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,FER,ATL1,ITGB7,EVL,DCC,FZD4,PTPN6,SHANK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,ARHGEF26,TSKU,IRS2,MAP2,LAMB1,GRB10,SEMA3C,NRP1,UNC5B,COBL,CTNND2,MEF2C,BCL11B,TYRO3,EFNB2,LRFN5,FARP1,FN1,ROBO2,BVES,LRP4,APBB1,OPHN1,LAMC3,KIF5C,SLC1A3,EPHB1,FOXG1,DOK5,NEO1,CHN1,LRRC55,NUMBL,LRRN1,SEMA4F,MAP1A,CNTN4,SCN1B,PDZD7,FLRT3,NCAM1,STXBP1,GFRA1,ZNF385A,EPB41L5,PDLIM7,DPYSL5,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,FERMT2,PALLD,PEAK1,BAIAP2,RERE,MAP1B,HEG1,DKK1,DOCK7,MATN2,NKX2-8,SEMA3A,SHTN1 |
| 5.040e-13 | -28.32 | ONDER_CDH1_TARGETS_2_UP | MSigDB lists | ONDER_CDH1_TARGETS_2_UP | 245 | 63 | 17377 | 1707 |
ENO2,FN1,FLVCR2,RHOBTB1,RECK,ZCCHC24,UGDH,ARHGAP22,EPS8,LMCD1,SLC7A2,PRKCA,CHN1,RGS17,RPS6KA2,TGFBR3,STC2,MARCH3,ACTA2,LIN7A,NAP1L3,TOX,GULP1,MARCKS,KLF9,PCOLCE2,MOXD1,PRR16,IGFBP3,DUSP1,CYP1B1,PNMA2,MICAL2,COL6A2,FOXN3,CRIP2,ARID5B,SDC3,FERMT2,SLITRK5,SATB2,ROR1,SLC46A3,LEPR,JAM3,FGFR1,EML1,MAP1B,BEX4,DDAH1,ENPP1,FAT4,GYPC,PLOD2,FBN1,ITGBL1,GRB10,NRP1,TPM1,CDH2,MLLT3,MME,SIX2 |
| 5.298e-13 | -28.27 | regulation of signaling | biological process | GO:0023051 | 3600 | 462 | 17256 | 1658 |
ARHGAP26,ACVR1,DUSP8,LGR4,GRIK2,VAMP8,GATA3,CTBP2,CHAC1,PRKCA,ABHD6,RAC3,EYA4,STK24,NOS1AP,SKI,TYMP,TGFBR3,PMAIP1,ZFYVE28,RAP2A,KCNS3,CHRDL1,RCAN3,NKX2-1,ACVR1C,WISP3,WLS,TGFA,LRRK2,DEPTOR,ACVR2B,FGF17,GPC6,ARHGEF26,GNAI1,ENPP1,SH3RF1,CCBE1,RASGRF2,PLK2,ADRB1,BMP1,ARHGAP28,BBC3,TMOD2,INPP5F,DIRAS1,SPRY4,NRP1,UNC5B,SPART,MEF2C,LATS2,ITGA6,OPHN1,BTBD9,TNFRSF10C,SLC1A3,APBA1,TNFRSF19,CHD5,GAS1,MYORG,MECOM,IL17D,CHN1,CNTN4,RALGPS2,PIK3AP1,MYC,FLRT3,C1QL4,PRELID1,SREBF1,SRGAP1,STXBP1,RIMS2,GPR161,ZNF385A,RNF152,HMGCR,PTCH2,RPL26,BDNF,DISC1,RAPGEF4,RYR2,HIP1,PEX5L,SHISA2,SNAP25,TAF4B,PLCB1,FAM162A,SH3GL2,PMEPA1,ADAMTS3,PELI2,THBS4,MPP2,INHBE,SPRED3,IQSEC2,CDH2,EPHA3,NBL1,BTC,RASAL2,RHOD,GPR65,RGS20,CHUK,GRK6,TMEM170B,NRXN1,DDR1,TIAM2,TLR3,KMO,CNKSR3,DACT1,MAGEA3,SHF,DAB2IP,MARCKS,PDE4D,FZD1,ADM2,FZD4,PFKFB2,SHANK2,PREX1,NLGN4X,ATF3,CBY1,PRKCQ,WNT11,ATP1B1,ASPH,TBC1D16,FGFR1,MAGI3,SNCA,IRS2,CXCL10,ARHGAP21,PRKCB,WFS1,APELA,WWTR1,ASIC1,PLEKHG1,MAP3K21,TNFSF15,GRB10,BMPR1A,MAPK10,MID1,CGB2,FARP1,C1QTNF3,EDA2R,IGFBP6,BACE1,FZD8,EPS8,BIK,ARL2,PSD3,GAS6,P2RY1,PKN1,EPHB1,RGS7,NDFIP2,KCNC4,GDPD5,TPD52L1,TSPAN17,PHLDA2,NEDD4,NEO1,RGS17,MCF2L,GHR,SGK3,RALGAPA2,DYNC2H1,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,PARP9,TRPM4,VEGFC,VAV3,SH3BP2,PXN,ARAP2,ARHGEF28,GSTM2,PTPN13,CACNA1E,MCF2L2,RAPGEF2,RASA3,GAREM1,RACK1,SKAP1,ZIC1,GPLD1,PTPRC,TRIB3,FGR,TERT,AKT3,XBP1,MCC,PCGF2,GRIN2D,BMP4,LRRK1,SHOX2,DDIT3,ATP2B4,FOXA1,BTRC,TPT1,ATP1A3,CACNG3,FGF13,TRIM16,SYT12,LMCD1,NDRG2,HDGFL3,ITPR2,ABAT,FAM13A,KREMEN1,F3,GSDME,ARHGEF10L,SIPA1L2,AKAP7,ITGB3,TRPC1,HRK,EPHB6,CTTN,PTPRE,MYRIP,ENO1,TLR4,SLIT2,PRKACB,PDGFRB,RASGRP1,CYP1B1,DBN1,CD55,ATF4,GCNT2,SESN2,SKAP2,ANK2,JPH1,YAP1,ROR1,PLEKHA1,SESN1,TSKU,INHBC,GSN,TCF7L1,KCNMB4,GPRC5B,HPSE,INSIG1,ERN1,TNFRSF1A,OXTR,DLX2,PPARGC1A,TNFSF4,APBA2,MAGI2,MLLT3,RRAGD,PRKAA2,TYRO3,RGS16,RUNX2,FN1,STXBP5L,LGALS3,RHOBTB1,BVES,UBASH3B,RASL11B,SORBS3,CHSY1,PFN2,IL18R1,DOK5,DDIT4,EFEMP1,CA2,IGF1R,BCHE,GATA2,PDE10A,LRP6,INAVA,BNIP3,FBXL2,BARX1,NOS3,PAK1,FGFR4,ATP5IF1,MID2,RHOQ,MSTN,SH2D2A,HOMER2,SPATA13,WWC1,STRADB,OBSCN,DUSP9,PDE8A,PRDM1,HERPUD1,BAIAP2,MAPKAPK2,GRIK4,RIPOR2,CSF1,HEYL,SH3BP4,EGFL7,SEMA3A,SFN,PRKN,SORBS1,ID1,NEK10,AVPI1,AKAP5,IL15,ARHGAP22,NTRK3,PIBF1,PPP1R9A,CBLN1,CYP26A1,UNC13B,BCL6,ACVR2A,WWC2,MET,SNAI2,GLI1,CTH,IGFBP3,INTU,FER,PRAME,TMEM65,NOP53,PTPN6,FGF12,RNF125,GSTO1,SYNJ2BP,CD40,CAMK2N1,SMAD3,NRG3,PTPRJ,GBP1,RBPMS2,ITGA2,RGS10,DUSP19,PTPRS,HGF,DISP1,SEPT5,LIFR,CTNND2,HEY1,ARFGEF3,TENM1,TNIK,DYRK3,NECAB2,SLC6A9,IL32,BMPR2,TSPAN15,GRB14,ARHGEF11,PAK5,REL,LRP4,CMTM8,NLRP14,TNFSF13B,CLSTN2,NOTUM,BMP6,ARHGAP44,MCU,SYDE2,NKX6-1,RAB11FIP5,CHN2,MAP1A,PRKCD,EHD3,STC2,RASD2,AFAP1L2,PCK2,IQGAP3,TNFRSF11A,TESPA1,SYK,ATP2B1,PCSK6,DUSP1,RAB3B,MSX1,KDM5B,CYTH3,SYBU,LITAF,ASAP3,GRID1,PRICKLE1,AGAP2,ARHGAP32,TLR6,SMPDL3B,DKK1,GPR37,ICA1,MYADM,TMEM237,EDA,NACC2,GCSAM,MPP7,FBN1,PRCP,MAP2K6,UACA,MAP3K20 |
| 5.393e-13 | -28.25 | cellular developmental process | biological process | GO:0048869 | 3666 | 469 | 17256 | 1658 |
THOC5,ACVR1,PDE1B,LGR4,LDLR,MCOLN3,GATA3,NPM1,ENAH,CEBPA,CTBP2,STAT5B,CHAC1,PRKCA,RAC3,STK24,NCS1,EYA4,TRPS1,SKI,TYMP,TGFBR3,RAP2A,CHRDL1,GSTM3,PACSIN1,POU3F3,NKX2-1,SLC9C1,ACVR1C,DCC,CAP2,LRRK2,FEZ1,ACVR2B,SAV1,ARHGEF26,SFXN1,SPATA9,HLF,NCKAP1L,WIPF3,PLK2,BDH2,BMP1,ADRB1,SEMA3C,SERPINI1,TMOD2,INPP5F,UNC5B,NRP1,TPM1,SPART,MEF2C,EFNB2,LRFN5,SEMA6B,MRC2,CELSR1,ZHX3,PTPRD,GABRB2,MLF1,ITGA6,OPHN1,TJP1,SLC1A3,HERC6,FOXG1,BBS9,CHD5,GAS1,MYORG,MECOM,CHN1,NAV1,CNTN4,SLC7A11,FRY,PDZD7,FLRT3,ZIC5,SREBF1,PRKG1,GRIP1,TOX,NCAM1,STXBP1,GFRA1,RIMS2,LRP12,ZNF385A,HMGCR,PTCH2,EPB41L5,ENAM,BDNF,DISC1,SPATA6,VLDLR,ARID5B,DCHS1,FHL2,FASN,SMARCD3,HIP1,SNAP25,TAF4B,PLCB1,CLN5,DAGLA,MMP15,TEX15,SH3GL2,WDR19,MATN2,INHBE,CDH17,CLMN,SFMBT1,SLFN5,DHCR7,CDH2,SMYD3,CSRP2,SHTN1,EPHA3,TFCP2L1,NBL1,ZNF516,DNM3,ST14,PLXNA2,PKP2,CHUK,NRXN1,DDR1,TXNRD3,EPB41L3,SPEG,GPRIN1,COL25A1,ALDOC,DAB2IP,PDE4D,SERPINH1,SNX10,ZNF365,MYT1,PERP,GAB2,FZD1,SSH3,MYLK3,FZD4,NKX3-2,SOX21,SHANK2,PREX1,ADCY1,NLGN4X,SATB2,PRKCQ,WNT11,CBY1,ATF3,RAB38,PYGO1,ATOH1,DSP,FGFR1,GJC1,IRS2,POPDC3,APELA,LAMB1,WWTR1,MAP3K21,KLF5,GRB10,BMPR1A,ATG5,MAPK10,STON2,COBL,WASF3,FARP1,C1QTNF3,EDA2R,ROBO2,PLAG1,FZD8,KIF5C,GAS6,P2RY1,EPHB1,GDPD5,NEDD4,COL27A1,NEO1,HOPX,LRRC55,IRX5,SOAT2,LRRN1,BHLHA15,MORN2,DYNC2H1,FIG4,NPTXR,GFI1,SMAD6,SPRY2,ZFP36L2,FES,VEGFC,B9D1,PDLIM7,LZTS3,ARHGEF28,RAPGEF2,GPLD1,ZIC1,HEG1,CEBPB,PTPRC,ID3,FGR,TERT,GNAO1,XBP1,MYOM2,BMP4,LRRK1,SHOX2,FOXA1,TPT1,TLL2,EXPH5,UGT8,FGF13,KIF5A,ACTL8,HDGFL3,LILRB1,NDRG2,RBM11,DNER,GSDME,RND2,EPCAM,EOMES,KCNAB1,DLX6,MARVELD2,ITGB3,POF1B,COL19A1,CTTN,EPHB6,ETV1,IL1RAP,SLIT2,RASGRP1,PDGFRB,DBN1,ATL1,TNK2,ITGB7,GPM6A,MARK1,ATF4,ANK2,NFE2L1,YAP1,CR2,PLEKHA1,ROR1,BATF,EML1,TSKU,DYRK1B,INHBC,GSN,TCF7L1,GPRC5B,NCAM2,MAP2,AHNAK2,DLX2,PPARGC1A,MAGI2,NEUROG2,UST,BCL11B,TYRO3,RUNX2,FN1,LGALS3,BVES,LAMC3,ZIC2,CHSY1,PHGDH,SPINK5,SATB1,ADGRG6,IL18R1,DOK5,FHOD3,DDIT4,NUMBL,SEMA4F,IGF1R,EEF2,ZNF354A,BCHE,GATA2,ADCY6,LRP6,BNIP3,SLCO4C1,BARX1,FGFR4,DPYSL5,PAK1,ATP5IF1,CDH26,UNC5C,SLITRK2,MSTN,SH2D2A,EFNA3,GPSM1,MAFB,STRADB,SLITRK5,OBSCN,PRDM1,SDK1,BAIAP2,NEGR1,ADGRB3,PLAGL1,RIPOR2,MFSD2A,HEYL,CSF1,RAI14,EGFL7,SEMA3A,NKX2-8,TESC,SFN,MME,SIX2,CREB3L2,PRKN,ZSWIM5,ID1,CELSR3,IL15,RBFOX2,ARHGAP22,COL18A1,HECW2,NTRK3,TDRKH,RADIL,DOCK2,PPP1R9A,CBLN1,SEMA6A,CTNNA2,KAZN,LHX6,BCL6,ZNF521,POU2F2,MET,ZNF488,TMEM120B,HSPA2,NTNG1,SEMA6C,SNAI2,IGFBP3,GLI1,INTU,PRAME,FER,EVL,PTPRU,PRDM13,PTPN6,VIM,AMIGO1,RARRES2,FRK,TTLL7,JAM3,BATF3,BCL11A,SMAD3,NRG3,PTK7,ITGA2,PTPRS,SOHLH2,HGF,CTNND2,HEY1,CNTN1,TENM1,TNIK,DYRK3,BMPR2,LRP4,NLRP14,APBB1,PRDM8,OVOL2,BMP6,ARHGAP44,NKX6-1,FOXP2,MAP1A,SCN1B,GTSF1,DSG2,PRKCD,KIAA0319,ACTA2,SGK1,SH3PXD2B,PCK2,RRAS2,TNFRSF11A,SYK,SLC45A3,PCSK6,MSX1,KDM5B,NR4A1,FOXN3,MEI1,FERMT2,ZFPM2,PALLD,FNDC3A,PEAK1,ILDR2,LEPR,MGMT,MAP1B,DKK1,RERE,DPY19L2,DOCK7,MYADM,FAT4,EDA,CTSV,SLC7A5,MYRF,MAP3K20,NPHP1,SNPH |
| 5.644e-13 | -28.20 | CUI_TCF21_TARGETS_2_DN | MSigDB lists | CUI_TCF21_TARGETS_2_DN | 770 | 139 | 17377 | 1707 |
ARHGAP26,CCDC126,TCP11L2,GATA3,PRKCA,TGFBR3,IKZF5,TRPC1,SLC2A12,TLR4,RAPGEF5,CD55,MARK1,COL4A3,MSRB3,ZDHHC14,EML1,ARHGEF26,GSN,AK1,WIPF3,ENTPD7,B3GALT2,ARHGAP28,SERPINI1,NRP1,TPM1,MAGI2,LPP,MEF2C,EFNB2,LATS2,CHCHD7,TBC1D1,SLK,SCD,SLC36A4,SPIRE1,MTUS1,FRY,ABCA5,PDE10A,PRKG1,TSPAN12,JAM2,MAST4,FMNL2,BTNL9,MYO10,PARD3B,COL4A4,ARID5B,RAPGEF4,EDEM3,CALCRL,MAFB,HIP1,ST6GALNAC3,PRDM1,MBNL2,KIAA0355,PELI2,SFMBT1,PLD1,SLFN5,PANK3,SORBS1,AMOTL1,MYO1B,HECW2,IL13RA1,KBTBD11,SPEG,TLR3,COL25A1,GULP1,PDE4D,PROS1,WWC2,GAB2,TMEM65,ADCY1,VIM,SYNJ2BP,DOCK5,TTLL7,DSP,FRK,PTPRJ,IGIP,WWTR1,PLEKHG1,BMPR1A,HS3ST3B1,CTTNBP2,LIFR,MYO1D,SERINC5,PLSCR4,BACE1,PSD3,COL4A5,SLC12A6,EPHB1,FAM174B,HOPX,ATXN7L1,FOXP2,TECPR1,EHD3,SGK3,SGK1,AFAP1L2,MYO6,RRAS2,MED12L,TMC7,RIN2,ARAP2,CRIM1,RAB6B,FERMT2,FNDC3A,PALLD,ILDR2,EBF1,PTPRC,CEBPB,MYADM,PLOD2,ACER2,PLXDC2,OSBPL5,MCC,UACA,MYOM2,SH3BGRL2,GEM,KIF1B |
| 7.220e-13 | -27.96 | myelodysplastic_syndrome | COSMIC cancer mutations | myelodysplastic_syndrome | 1191 | 192 | 17385 | 1698 |
ARHGAP26,ACVR1,GATA3,NPM1,CEBPA,CADM2,SYT14,PRKCA,DNER,FSTL5,STK24,PCDH7,PLS3,PPM1E,RPS6KA2,TGFBR3,KCNN2,ZFYVE28,DNAH6,ANKFN1,ATRNL1,SLC2A12,TMEM132E,TSHR,FANK1,SLIT2,PRKACB,PDGFRB,ZNF391,TNK2,MARK1,SKAP2,EML6,DCDC1,COL4A3,ACVR1C,DCC,LRRK2,NFIA,KCND3,ROR1,ACVR2B,SGK2,TCERG1L,GPC6,EML1,DYRK1B,PLK2,ERN1,ARHGAP28,MAPK13,NRP1,APBA2,MAGI2,PRKAA2,UST,LATS2,FN1,STXBP5L,PTPRD,SETBP1,CHSY1,FHOD3,MECOM,PCDHB14,CA2,SLC7A11,IGF1R,ADCK1,ABCA5,PIK3AP1,GATA2,MYC,PRKG1,FAM107B,CADPS2,ALPK1,SLCO4C1,FAM155A,LRP12,PAK1,FGFR4,UNC5C,KCNQ3,STAT4,ARID5B,FHL2,STRADB,OBSCN,PEX5L,SDK1,CDC42BPA,B4GALNT3,KHDRBS2,MBNL2,NEGR1,MAPKAPK2,CACHD1,GRIK4,TEX15,SH3GL2,PKN3,MPP2,RAB31,PTPRN2,DIRC2,DMXL2,EPHA3,NEK10,HECW2,CHUK,NTRK3,GRK6,SPATS2L,SLC7A2,DDR1,TNKS1BP1,DOCK2,DDX60L,SEMA6A,SPEG,COL22A1,KCTD15,COL25A1,RPS6KL1,MYO3B,ACVR2A,MET,FER,MYLK3,PDK1,NECAB1,PFKFB2,KCNH5,NLGN4X,PRKCQ,FRK,FGFR1,RANBP2,NRG3,POPDC3,PRKCB,PTK7,GRB10,BMPR1A,CTTNBP2,MID1,MAST1,ANO10,MYO1D,TNIK,DYRK3,TMEM132C,C1QTNF3,BMPR2,CLSTN2,NKAIN2,COL4A5,PKN1,EPHB1,ZNF219,GDPD5,ATXN7L1,LRRC55,PRKCD,SGK3,SGK1,SYK,FES,MN1,MICAL2,CLYBL,ESRRG,GRID1,NUAK2,ZFPM2,PALLD,ILDR2,MGMT,EBF1,ADAMTS17,NSD1,TRIB3,DDAH1,FGR,TERT,AKT3,MAP2K6,THSD7B,NEK11,CERS1,SLC16A10 |
| 7.220e-13 | -27.96 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | 1191 | 192 | 17385 | 1698 |
ARHGAP26,ACVR1,GATA3,NPM1,CEBPA,CADM2,SYT14,PRKCA,DNER,FSTL5,STK24,PCDH7,PLS3,PPM1E,RPS6KA2,TGFBR3,KCNN2,ZFYVE28,DNAH6,ANKFN1,ATRNL1,SLC2A12,TMEM132E,TSHR,FANK1,SLIT2,PRKACB,PDGFRB,ZNF391,TNK2,MARK1,SKAP2,EML6,DCDC1,COL4A3,ACVR1C,DCC,LRRK2,NFIA,KCND3,ROR1,ACVR2B,SGK2,TCERG1L,GPC6,EML1,DYRK1B,PLK2,ERN1,ARHGAP28,MAPK13,NRP1,APBA2,MAGI2,PRKAA2,UST,LATS2,FN1,STXBP5L,PTPRD,SETBP1,CHSY1,FHOD3,MECOM,PCDHB14,CA2,SLC7A11,IGF1R,ADCK1,ABCA5,PIK3AP1,GATA2,MYC,PRKG1,FAM107B,CADPS2,ALPK1,SLCO4C1,FAM155A,LRP12,PAK1,FGFR4,UNC5C,KCNQ3,STAT4,ARID5B,FHL2,STRADB,OBSCN,PEX5L,SDK1,CDC42BPA,B4GALNT3,KHDRBS2,MBNL2,NEGR1,MAPKAPK2,CACHD1,GRIK4,TEX15,SH3GL2,PKN3,MPP2,RAB31,PTPRN2,DIRC2,DMXL2,EPHA3,NEK10,HECW2,CHUK,NTRK3,GRK6,SPATS2L,SLC7A2,DDR1,TNKS1BP1,DOCK2,DDX60L,SEMA6A,SPEG,COL22A1,KCTD15,COL25A1,RPS6KL1,MYO3B,ACVR2A,MET,FER,MYLK3,PDK1,NECAB1,PFKFB2,KCNH5,NLGN4X,PRKCQ,FRK,FGFR1,RANBP2,NRG3,POPDC3,PRKCB,PTK7,GRB10,BMPR1A,CTTNBP2,MID1,MAST1,ANO10,MYO1D,TNIK,DYRK3,TMEM132C,C1QTNF3,BMPR2,CLSTN2,NKAIN2,COL4A5,PKN1,EPHB1,ZNF219,GDPD5,ATXN7L1,LRRC55,PRKCD,SGK3,SGK1,SYK,FES,MN1,MICAL2,CLYBL,ESRRG,GRID1,NUAK2,ZFPM2,PALLD,ILDR2,MGMT,EBF1,ADAMTS17,NSD1,TRIB3,DDAH1,FGR,TERT,AKT3,MAP2K6,THSD7B,NEK11,CERS1,SLC16A10 |
| 7.429e-13 | -27.93 | generation of neurons | biological process | GO:0048699 | 1443 | 220 | 17256 | 1658 |
UGT8,FGF13,KIF5A,LDLR,MCOLN3,GATA3,HDGFL3,ENAH,PRKCA,DNER,RAC3,NCS1,STK24,GSDME,SKI,RND2,EOMES,RAP2A,CTTN,PACSIN1,ETV1,SLIT2,IL1RAP,NKX2-1,DBN1,ATL1,GPM6A,MARK1,ATF4,DCC,LRRK2,YAP1,FEZ1,EML1,TSKU,TCF7L1,GPRC5B,NCAM2,NCKAP1L,MAP2,PLK2,SEMA3C,SERPINI1,INPP5F,DLX2,SPART,UNC5B,NRP1,MAGI2,NEUROG2,MEF2C,UST,BCL11B,EFNB2,LRFN5,RUNX2,FN1,CELSR1,PTPRD,GABRB2,OPHN1,SLC1A3,PHGDH,SPINK5,FOXG1,CHD5,DOK5,DDIT4,CHN1,NUMBL,NAV1,CNTN4,SEMA4F,FRY,PDZD7,BCHE,GATA2,FLRT3,PRKG1,GRIP1,LRP6,ADCY6,NCAM1,STXBP1,GFRA1,RIMS2,LRP12,PAK1,DPYSL5,UNC5C,BDNF,DISC1,SLITRK2,VLDLR,EFNA3,SMARCD3,SLITRK5,PRDM1,SNAP25,SDK1,CLN5,BAIAP2,NEGR1,DAGLA,ADGRB3,SH3GL2,CSF1,HEYL,MATN2,CLMN,NKX2-8,CDH2,SEMA3A,SHTN1,EPHA3,PRKN,NBL1,ZSWIM5,ID1,DNM3,CELSR3,RBFOX2,PLXNA2,HECW2,NTRK3,NRXN1,DDR1,CBLN1,SEMA6A,PPP1R9A,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,ZNF521,BCL6,DAB2IP,ZNF488,ZNF365,NTNG1,SEMA6C,FZD1,GAB2,SSH3,EVL,FZD4,SHANK2,ADCY1,PREX1,NLGN4X,PRKCQ,WNT11,VIM,SATB2,ATOH1,AMIGO1,JAM3,FGFR1,IRS2,NRG3,PTK7,LAMB1,PTPRS,GRB10,HGF,BMPR1A,MAPK10,COBL,CTNND2,CNTN1,TENM1,TNIK,FARP1,BMPR2,ROBO2,PLAG1,FZD8,LRP4,APBB1,KIF5C,GAS6,EPHB1,GDPD5,BMP6,NEDD4,ARHGAP44,NEO1,NKX6-1,LRRC55,IRX5,MAP1A,LRRN1,SCN1B,KIAA0319,SGK1,FIG4,DYNC2H1,NPTXR,GFI1,SLC45A3,FES,VEGFC,PDLIM7,LZTS3,RAPGEF2,RERE,MAP1B,DKK1,CEBPB,ID3,DOCK7,FAT4,TERT,GNAO1,XBP1,BMP4,SHOX2,FOXA1,SNPH |
| 7.717e-13 | -27.89 | MODULE_11 | MSigDB lists | MODULE_11 | 511 | 103 | 17377 | 1707 |
TRIM2,ACSL1,CACNG3,DUSP8,TRIM16,CELSR3,RNF144A,RHOD,PLXNA2,ABAT,KIF21B,NRXN1,NOVA1,RAC3,CBLN1,F3,RTN1,EPB41L3,TACC2,BCL6,MAP7,NAP1L3,CPE,HSPA2,GATM,SLIT2,NTNG1,PRKACB,DBN1,GPM6A,MEIS2,FEZ1,TMEM47,FGFR1,PLEKHB1,BCL11A,TRIM9,HLF,GPRC5B,INSIG1,PRKCB,MAP2,MAOA,ZBTB20,SERPINI1,DBP,APBA2,MAPK10,MAGI2,PSPH,MEF2C,TYRO3,WASF3,SV2B,COL9A3,ENO2,PTPRD,ATP9A,ITGA6,ST6GAL1,APBB1,GABRG2,SETBP1,KIF5C,ZIC2,SLC1A3,RGS7,MLC1,INPP1,DYNC1I1,GDPD5,FOXG1,NEO1,MTUS1,HOPX,ABLIM1,KCNJ4,CHN2,CA2,SCN1B,NOVA2,PCBP4,SGK1,NCAM1,TBC1D9,COL9A2,RIMS2,ATP2B1,IGSF3,MYO10,SMARCD3,SNAP25,PLCB1,CD37,FAT1,GNAO1,RAB31,PTPRN2,CDH2,KIF1B,CSRP2,PKIA,SNPH |
| 8.163e-13 | -27.83 | LIU_PROSTATE_CANCER_DN | MSigDB lists | LIU_PROSTATE_CANCER_DN | 449 | 94 | 17377 | 1707 |
TFCP2L1,NBL1,SORBS1,ID1,FHDC1,GATA3,C20orf194,ENAH,COL14A1,SLCO3A1,EYA4,PCDH7,ZNF827,EPB41L3,SPEG,NELL2,TGFBR3,GRHL1,STARD4,CHRDL1,SCRN1,GSTM3,DAB2IP,MET,KLHL29,GATM,SNAI2,TUBA1A,ANK2,FEZ1,MSRB3,TNS1,RARRES2,TTC28,GPC6,FGFR1,GJC1,HLF,GYPC,WFS1,LAMB1,ITGA2,AHNAK2,BDH2,UNC5B,TPM1,NR3C2,C2orf88,KLF8,STOX2,MRC2,ENO2,TBC1D1,ISYNA1,GAS6,INPP1,FHOD3,COL27A1,MECOM,EFEMP1,CHN1,FLRT3,GPR155,PRICKLE2,ACTA2,SH3PXD2B,NCAM1,GLIS1,GPR161,SNX7,FADS1,VAV3,SYNPO2,ALDH2,GSTM2,CRIM1,FERMT2,C1R,PALLD,MAP1B,CACHD1,PLEKHH2,RIMKLB,TMEM237,PLAGL1,FBN1,MFSD2A,LAPTM4B,SVIL,HOXD13,CSRP2,MME,ATP2B4,STOM |
| 1.119e-12 | -27.52 | STK33_SKM_DN | MSigDB lists | STK33_SKM_DN | 243 | 62 | 17377 | 1707 |
MTG1,PHACTR3,MOCOS,RGS16,GRB14,GALNT12,MYO1B,MCTP2,FAM117B,SCD,CA8,TPD52L1,TBC1D30,BEX2,SYDE2,TXNRD3,SLC35F1,FOXP2,ABLIM1,ASNS,KCNN2,BACE2,KAZN,STC2,TMEM143,ZDHHC23,SLC6A15,TSPAN13,MARCKS,FAM84B,SLCO4C1,RAB27B,ZNF488,OR2W3,RAPGEF5,CRIM1,ALDH1L2,CRIP2,LRRK2,JPH1,OGDHL,SLITRK5,MSRB3,PLS1,SHISA2,PRKAR2B,RAB38,C3orf70,SNTB1,C4orf19,ARHGEF26,GPR37,ID3,TEX15,THBS4,PCGF2,SH3BGRL2,GRB10,TANC2,PSPH,FRMD5,SLC43A1 |
| 1.267e-12 | -27.39 | MODULE_137 | MSigDB lists | MODULE_137 | 522 | 104 | 17377 | 1707 |
TRIM2,ACSL1,CACNG3,DUSP8,CELSR3,RNF144A,PLXNA2,ABAT,NRXN1,KIF21B,NOVA1,RAC3,CBLN1,F3,RTN1,EPB41L3,TACC2,MAP7,SCRN1,NAP1L3,CPE,HSPA2,GATM,PRKACB,IGFBP3,DBN1,PRAME,GPM6A,MEIS2,COL6A2,FEZ1,ROR1,TMEM47,ATP1B1,PLEKHB1,FGFR1,BCL11A,TRIM9,GPRC5B,INSIG1,PRKCB,MAP2,EIF4EBP1,MAOA,ZBTB20,SERPINI1,DBP,SEPT5,APBA2,MAPK10,MAGI2,MEF2C,TYRO3,WASF3,COL9A3,SV2B,GNG12,IGFBP6,ENO2,PTPRD,ATP9A,ITGA6,APBB1,GABRG2,SETBP1,KIF5C,ZIC2,SLC1A3,RGS7,DYNC1I1,MLC1,FOXG1,INPP1,MTUS1,NEO1,ABLIM1,KCNJ4,CHN2,CA2,NOVA2,SCN1B,PCBP4,TBC1D9,NCAM1,STXBP1,COL9A2,RIMS2,PFKFB4,MYO10,NR4A1,SMARCD3,SNAP25,PLCB1,ZIC1,RND3,THBS4,FAT1,GNAO1,RAB31,PTPRN2,CDH2,PKIA,CSRP2,SNPH |
| 1.446e-12 | -27.26 | oesophagus-lower_third-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-adenocarcinoma | 6451 | 764 | 17385 | 1698 |
ARHGAP26,DOC2A,GXYLT2,GRIK2,AASS,CNTNAP3,PRSS12,RECK,TUBE1,STAT5B,CTBP2,CADM2,CHAC1,DOCK3,KIAA1217,SNX9,CA8,EYA4,EPDR1,BAG3,IKZF5,TMED9,COG3,CPE,TSHR,NKX2-1,MEIS2,SMAD9,DCC,EXOC6B,TGFA,GJB2,LRRK2,FEZ1,PRKAR2B,ABCC2,FGF17,MFSD6,INTS6,SLC7A1,ENPP1,ATP7B,MAP9,ARHGAP28,ERCC5,DIRAS1,ZBTB20,CAB39L,DNHD1,TMEFF2,SCN5A,GNG12,TMEM63C,TJP1,SLC36A4,BTBD9,FOXG1,SYCP2,FRY,CACNB2,FLRT3,SRGAP1,TOX,CADPS2,ALPK1,ST8SIA1,NCAM1,ZNF518B,JAM2,TSPAN9,GFRA1,LRP12,CHRM3,ZNF385A,BDNF,SLC37A1,KCNQ3,MYO10,STAT4,FASN,RYR2,HIP1,CALCRL,PLS1,C1R,ST6GALNAC3,ZBBX,TAF4B,MBNL2,CLN5,C11orf45,DHX32,CACHD1,TEX15,TMCO3,RIMKLB,SH3GL2,ADAMTS3,CDH2,DOCK9,MTG1,MYO1B,LRRCC1,RGS20,BEGAIN,PKP2,ADD2,NRXN1,TXNRD3,EPB41L3,TLR3,CHRNA5,CNKSR3,COL25A1,DACT1,PJA1,FAM155B,RPL26L1,ZNF365,DNAH5,MYT1,KCNB2,SCN3A,FZD1,DZANK1,SSH3,MYLK3,GARS,COL6A2,RNF145,NECAB1,KCNH5,TRAM1L1,ADCY1,DSP,ASPH,METAP1D,FGFR1,SLC39A14,ARHGAP21,GPR160,WWTR1,LAMB1,INPP4B,PLEKHG1,PLD5,KLHL31,SERINC5,CCDC148,FARP1,C1QTNF3,ROBO2,FZD8,CD276,IPO5,UBAC2,NKAIN2,PSD3,CBS,CREB5,PKN1,EPHB1,ZNF219,KCNC4,COL27A1,HMGCS1,LRRN1,GHR,ZFP36L2,MED12L,PARP9,TRPM4,MCF2L2,RAPGEF2,RASA3,ATP11A,SNTB1,HEG1,PTPRC,RPL12,PCDHB7,NEK11,BMP4,HK1,SHOX2,CRISPLD1,PHC1,TLL2,PHACTR3,TRIM2,CACNG3,FGF13,SYT12,LMCD1,ASS1,ITPR2,FAM13A,FSTL5,PLS3,RND2,RUFY4,FKBP9,RPS6KA2,TM9SF2,SEC16B,MARVELD2,COL19A1,LIN7A,JAKMIP2,KIAA1614,TLN2,TMEM132E,TLR4,ETV1,NEB,SLC3A2,MARK1,ABCC4,COL4A3,ANK2,CR2,TCERG1L,SESN1,CRYBG3,TRIM9,KLF12,MAP2,P4HA2,TECPR2,CCDC146,AHNAK2,PIK3C2B,TC2N,RRAGD,LONRF1,PRKAA2,KCNV1,RUNX2,STXBP5L,UBASH3B,SETBP1,ZNF215,MLC1,SPIRE1,FHOD3,EFEMP1,NUMBL,ZBTB38,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,FRAS1,PDE10A,LRP6,SLCO4C1,FAR2,NIPAL2,FBXL2,FGFR4,CHSY3,DPYSL5,UNC5C,BTNL9,MGAT4B,SPATA13,PPFIA4,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,TEX9,NEGR1,NAP1L5,SLC2A6,PLD1,TESC,MME,SIX2,ID1,CFH,DOCK1,RNF24,ZNF83,NTRK3,OR51B4,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,CBLN1,PCLO,FAM131B,ZNF362,IDI1,TACC2,BCL6,EEPD1,CLVS2,SCN2A,TMEM56,CTH,GLI1,INTU,EVL,CSN2,TMEM65,LRRC8B,THSD4,CHRNA6,PAGE5,FRK,JAM3,RANBP2,NRG3,PTPRJ,KCNG1,PTPRS,MAOA,HGF,SUSD4,ZNF701,CTNND2,CNTN1,HEY1,MAN2B2,COL9A3,PCDH18,DYRK3,IL32,BMPR2,GABRG2,PRDM8,RASD1,USP30,PPP2R3A,SLC35F1,TTC1,FOXP2,MAP1A,GTF2F2,TSC22D1,PRICKLE2,KIAA0408,SH3PXD2B,PCK2,SYK,SLC45A3,KIAA1211,ATP2B1,DLGAP1,MICAL2,LRRIQ1,FOXN3,NUAK2,FERMT2,PRICKLE1,PALLD,NPDC1,MKX,DKK1,EBF1,CD37,DOCK7,FAT4,FBN1,L3MBTL4,ZNF214,ZNF808,DLG2,RPL4,TBC1D4,KIF1B,CACNA2D1,FILIP1,ZNF235,FAM171B,MYCBP2,PPP4R4,LANCL3,LGR4,ATP8A1,LDLR,ENAH,PRKCA,NCS1,TRPS1,SERINC2,KCNS3,GSTM3,ATRNL1,PACSIN1,PLTP,GLDC,GDAP1,ERGIC1,WISP3,KLHL3,NR6A1,KLHL4,DNAJC6,LRMP,SLC25A28,TNS1,ACVR2B,GPC6,GNAI1,AHRR,SFXN1,SH3RF1,NCKAP1L,PLK2,RASGRF2,BMP1,SERPINI1,DSEL,NRP1,LZTS1,SPOCK3,EFNB2,SEMA6B,LRFN5,MRC2,INPPL1,FAM124A,CELSR1,PTPRD,ZHX3,TBC1D1,GABRB2,DHCR24,OPHN1,ISYNA1,WDFY4,APBA1,DYNC1I1,PRRG4,MTUS1,GBGT1,NAV1,SLC7A11,RALGPS2,CNTN4,RUNDC3B,SREBF1,CPXM2,GRIP1,MPDZ,SAMD13,COL9A2,RIMS2,RNF152,IGSF3,EPB41L5,PTCH2,DISC1,TBC1D8B,SLC36A1,COL4A4,VLDLR,RAPGEF4,PACSIN3,KIAA1324L,PEX5L,CCDC85A,CDC42BPA,PLCB1,TMEM74,MMP15,DAGLA,PLEKHH2,PKN3,ISM1,CECR2,MPP2,SLFN5,SMYD3,AMPD1,EPHA3,RASAL2,ST14,RNF144A,ZNF311,PLXNA2,OTX1,MSR1,COL14A1,ZFYVE9,NELL2,ZNF827,SPEG,TMEM53,ALDOC,SHF,NBEA,DAB2IP,NAP1L3,PDE4D,GATM,GAB2,TRDMT1,PDK1,TMEM43,PREX1,NLGN4X,SATB2,PRKCQ,PYGO1,TBC1D16,ATP10D,SNCA,HTR7,IKZF3,POPDC3,PRKCB,TDO2,CCNA1,MAP3K21,BMPR1A,CTTNBP2,NR3C2,STON2,PURG,COBL,HACE1,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,EPS8,PRSS35,HERC5,KIF5C,GABRR2,NDFIP2,PHLDA2,NEDD4,SOAT2,AFF2,SGK3,SLC6A15,DYNC2H1,FIG4,ERRFI1,SMAD6,GFI1,SEPT3,SMPDL3A,B4GALT6,TMC7,VAV3,SLC40A1,ARHGEF28,SYNPO2,CACNA1E,MPP1,PTPN13,ZDHHC15,UCHL3,GUCY1A2,SKAP1,GPR137C,GPLD1,OR2T33,PLXDC2,MCC,SVIL,PGM2L1,MYOM2,LARP1,EXPH5,UGT8,KIF5A,ACTL8,PTPN21,TNFAIP8L2,C20orf194,RBM11,KREMEN1,HMCN1,SLCO3A1,CHST10,QPRT,RTN1,ARHGEF10L,SIPA1L2,LRRC6,GRHL1,AKAP7,ABI3BP,ANKFN1,POF1B,CNNM2,TRPC1,PCOLCE2,MYRIP,SLIT2,IL1RAP,CYP1B1,TNK2,SKAP2,YAP1,ROR1,RNF44,SERGEF,EML1,TMEM132B,TMEM150B,NCAM2,FAM114A2,PPARGC1A,APBA2,MAGI2,PCSK5,GPT2,SV2B,MOCOS,FN1,OTOGL,BVES,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,FAM81A,SPINK5,PHGDH,CD7,PCDHB14,CA2,EEF2,FAM107B,LIMCH1,LRP3,CAND2,SNX7,NOS3,CDH26,GPR176,PCDH10,RAX,PODXL2,SLITRK2,SH2D2A,PARD3B,GSTM4,EDEM3,DUSP9,WWC1,LHPP,B4GALNT3,AMDHD1,PLAGL1,KIAA0355,FCHO2,FAT1,HK2,RAI14,DISP2,NKX2-8,OSBPL6,XKR4,CREB3L2,DMXL2,EML5,ZSWIM5,SORBS1,CELSR3,PLEKHA5,COL18A1,COBLL1,BCL6B,TDRKH,CANX,PIBF1,DOCK2,ZSCAN5A,SCIN,COL22A1,KCTD15,PDZD8,UNC13B,KAZN,PPFIBP1,ZNF521,ACVR2A,PROS1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SEMA6C,DPP10,PHLDB2,FER,PRAME,ANTXR2,PTPRU,TTLL7,DOCK5,TPK1,BCL11A,ZNF569,ARMC4,MAGEA12,MSC,ZNF93,BACH2,SOHLH2,DISP1,MAST1,PRSS16,ARHGEF11,CLSTN2,COL4A5,IGF2BP2,NOTUM,OVOL2,KCNJ4,PRKCD,STC2,KIAA0319,TRIM3,AFAP1L2,IQGAP3,RRAS2,PNMA2,CARD6,MSX1,CRIM1,NR4A1,GRID1,ASAP3,MEI1,PRRG1,PHACTR2,ARHGAP32,C3orf70,ZFPM2,NAALADL2,RERE,GPR37,DPY19L2,ADAMTS17,EDA,MPP7,MAP2K6,THSD7B,SLC7A5,UACA,KIF21A,GEM,MMP16,NPHP1,ABCG1,SNPH |
| 1.706e-12 | -27.10 | localization of cell | biological process | GO:0051674 | 955 | 159 | 17256 | 1658 |
ACVR1,FGF13,JCHAIN,GATA3,STAT5B,DNER,RAC3,SKI,EPCAM,RND2,TGFBR3,LRRC6,DNAH6,ITGB3,CTTN,PLTP,SLIT2,POU3F3,PDGFRB,NKX2-1,CYP1B1,CFAP44,TNK2,ITGB7,GPM6A,SLC3A2,MARK1,DCC,SLC9C1,LRRK2,EFHC1,TNS1,GPC6,NCKAP1L,SEMA3C,PIK3C2B,NRP1,TMEFF2,SLC9B1,MEF2C,BCL11B,EFNB2,TYRO3,FN1,CELSR1,LGALS3,BVES,ITGA6,OPHN1,FOXG1,DDIT4,MCOLN2,NAV1,SLC7A11,SEMA4F,GATA2,FLRT3,PRKG1,JAM2,LRP12,NOS3,EPB41L5,PAK1,FGFR4,DISC1,PODXL2,RHOQ,ARID5B,DCHS1,SPATA13,SDC3,WWC1,CDC42BPA,PKN3,THBS4,FAT1,MATN2,PLD1,CDH2,SEMA3A,SIX2,SHTN1,EPHA3,CXCR5,AMOTL1,ID1,RHOD,DOCK1,CELSR3,RBFOX2,PSTPIP2,PLXNA2,ADD2,NTRK3,DDR1,CTNNA2,GPR15,PLPP1,LHX6,DAB2IP,PROS1,PDE4D,DNAH5,SNAI2,DOCK8,FER,PTPN6,PREX1,PRKCQ,WNT11,SATB2,ATOH1,ATP1B1,FRK,JAM3,CENPV,FGFR1,CXCL10,NRG3,GYPC,APELA,PTK7,LAMB1,ITGA2,HGF,HOXB9,PAK5,GRB14,EPS8,SELL,GAS6,P2RY1,OVOL2,PKN1,EPHB1,NKX6-1,PRKCD,KIAA0319,TNFRSF11A,SYK,FES,PARP9,VEGFC,TRPM4,VAV3,PXN,RAPGEF2,NR4A1,ASAP3,PALLD,PEAK1,GPLD1,RERE,MAP1B,PTPRC,FGR,RND3,SLC7A5,ATP2B4 |
| 1.706e-12 | -27.10 | cell motility | biological process | GO:0048870 | 955 | 159 | 17256 | 1658 |
ACVR1,FGF13,JCHAIN,GATA3,STAT5B,DNER,RAC3,SKI,EPCAM,RND2,TGFBR3,LRRC6,DNAH6,ITGB3,CTTN,PLTP,SLIT2,POU3F3,PDGFRB,NKX2-1,CYP1B1,CFAP44,TNK2,ITGB7,GPM6A,SLC3A2,MARK1,DCC,SLC9C1,LRRK2,EFHC1,TNS1,GPC6,NCKAP1L,SEMA3C,PIK3C2B,NRP1,TMEFF2,SLC9B1,MEF2C,BCL11B,EFNB2,TYRO3,FN1,CELSR1,LGALS3,BVES,ITGA6,OPHN1,FOXG1,DDIT4,MCOLN2,NAV1,SLC7A11,SEMA4F,GATA2,FLRT3,PRKG1,JAM2,LRP12,NOS3,EPB41L5,PAK1,FGFR4,DISC1,PODXL2,RHOQ,ARID5B,DCHS1,SPATA13,SDC3,WWC1,CDC42BPA,PKN3,THBS4,FAT1,MATN2,PLD1,CDH2,SEMA3A,SIX2,SHTN1,EPHA3,CXCR5,AMOTL1,ID1,RHOD,DOCK1,CELSR3,RBFOX2,PSTPIP2,PLXNA2,ADD2,NTRK3,DDR1,CTNNA2,GPR15,PLPP1,LHX6,DAB2IP,PROS1,PDE4D,DNAH5,SNAI2,DOCK8,FER,PTPN6,PREX1,PRKCQ,WNT11,SATB2,ATOH1,ATP1B1,FRK,JAM3,CENPV,FGFR1,CXCL10,NRG3,GYPC,APELA,PTK7,LAMB1,ITGA2,HGF,HOXB9,PAK5,GRB14,EPS8,SELL,GAS6,P2RY1,OVOL2,PKN1,EPHB1,NKX6-1,PRKCD,KIAA0319,TNFRSF11A,SYK,FES,PARP9,VEGFC,TRPM4,VAV3,PXN,RAPGEF2,NR4A1,ASAP3,PALLD,PEAK1,GPLD1,RERE,MAP1B,PTPRC,FGR,RND3,SLC7A5,ATP2B4 |
| 2.006e-12 | -26.93 | DURAND_STROMA_S_UP | MSigDB lists | DURAND_STROMA_S_UP | 277 | 67 | 17377 | 1707 |
PDE1B,IL15,PLXNA2,MORC4,GATA3,NDRG2,IL13RA1,DOCK3,NOVA1,FAM110B,RAC3,SP8,EYA4,RNF150,SPEG,RTKN2,MARCKS,PDE4D,PDGFRB,SNAI2,FZD1,C3orf67,EIF4E3,COL6A2,SLC39A8,TRAM1L1,TMEM47,PYGO1,ZNF618,CA13,TCF7L1,POPDC3,BACH2,RBPMS2,MAP9,INPP4B,ARHGAP28,TMEFF2,UST,MYO1D,RHOBTB1,FZD8,ST6GAL1,UBASH3B,CYP2J2,GALNT13,SLC1A3,SCN1B,EHD3,TFAP2A,NCAM1,MN1,MID2,CRIP2,ZDHHC15,PRRG1,SDC3,CALCRL,MMP15,TEX15,PLAGL1,FAT4,GNAO1,MATN2,TMEM117,PAX9,SLC43A1 |
| 2.092e-12 | -26.89 | MODULE_100 | MSigDB lists | MODULE_100 | 519 | 103 | 17377 | 1707 |
TRIM2,ACSL1,CACNG3,DUSP8,CELSR3,RNF144A,PLXNA2,ABAT,NRXN1,KIF21B,NOVA1,RAC3,CBLN1,F3,RTN1,EPB41L3,TACC2,MAP7,SCRN1,NAP1L3,CPE,HSPA2,GATM,PRKACB,IGFBP3,DBN1,PRAME,GPM6A,MEIS2,COL6A2,FEZ1,ROR1,TMEM47,ATP1B1,PLEKHB1,FGFR1,BCL11A,TRIM9,GPRC5B,INSIG1,PRKCB,MAP2,MAOA,ZBTB20,SERPINI1,DBP,SEPT5,APBA2,MAPK10,MAGI2,MEF2C,TYRO3,WASF3,COL9A3,SV2B,GNG12,IGFBP6,ENO2,PTPRD,ATP9A,ITGA6,APBB1,GABRG2,SETBP1,KIF5C,ZIC2,SLC1A3,RGS7,DYNC1I1,MLC1,FOXG1,INPP1,MTUS1,NEO1,ABLIM1,KCNJ4,CHN2,CA2,NOVA2,SCN1B,PCBP4,TBC1D9,NCAM1,STXBP1,COL9A2,RIMS2,PFKFB4,MYO10,NR4A1,SMARCD3,SNAP25,PLCB1,ZIC1,RND3,THBS4,FAT1,GNAO1,RAB31,PTPRN2,CDH2,PKIA,CSRP2,SNPH |
| 2.338e-12 | -26.78 | MODULE_66 | MSigDB lists | MODULE_66 | 527 | 104 | 17377 | 1707 |
TRIM2,ACSL1,CACNG3,DUSP8,CELSR3,RNF144A,PLXNA2,ABAT,KIF21B,NRXN1,NOVA1,RAC3,CBLN1,F3,RTN1,EPB41L3,TACC2,MAP7,SCRN1,NAP1L3,CPE,HSPA2,GATM,PRKACB,IGFBP3,DBN1,PRAME,GPM6A,MEIS2,COL6A2,FEZ1,TMEM47,ROR1,ATP1B1,FGFR1,PLEKHB1,BCL11A,TRIM9,GPRC5B,INSIG1,PRKCB,MAP2,MAOA,ZBTB20,SERPINI1,DBP,SEPT5,APBA2,MAPK10,MAGI2,MEF2C,TYRO3,WASF3,SV2B,GNG12,COL9A3,ENO2,IGFBP6,PTPRD,ATP9A,ITGA6,APBB1,GABRG2,SETBP1,KIF5C,ZIC2,SLC1A3,RGS7,MLC1,INPP1,DYNC1I1,FOXG1,NEO1,MTUS1,ABLIM1,KCNJ4,CHN2,CA2,SCN1B,NOVA2,PCBP4,NCAM1,TBC1D9,STXBP1,COL9A2,RIMS2,ATP2B1,PFKFB4,MYO10,NR4A1,SMARCD3,SNAP25,PLCB1,ZIC1,RND3,FAT1,GNAO1,THBS4,RAB31,PTPRN2,CDH2,CSRP2,PKIA,SNPH |
| 2.610e-12 | -26.67 | GO_LOCOMOTION | MSigDB lists | GO_LOCOMOTION | 1049 | 173 | 17377 | 1707 |
ACVR1,FGF13,KIF5A,LDLR,VAMP8,GATA3,ENAH,STAT5B,DNER,SKI,TYMP,TGFBR3,LRRC6,DNAH6,ITGB3,CTTN,PLTP,ETV1,SLIT2,POU3F3,PDGFRB,LAMP3,NKX2-1,CYP1B1,TNK2,ITGB7,GPM6A,CD55,SLC3A2,MARK1,DCC,LRRK2,FEZ1,CR2,TNS1,EFHC1,GPC6,SPNS1,NCKAP1L,SEMA3C,UNC5B,TMEFF2,NRP1,MEF2C,TYRO3,BCL11B,EFNB2,SEMA6B,CELSR1,LGALS3,FN1,BVES,ITGA6,OPHN1,DDIT4,CHN1,NAV1,CNTN4,SEMA4F,SLC7A11,GATA2,FLRT3,PRKG1,NCAM1,JAM2,NOS3,FGFR4,EPB41L5,DPYSL5,BDNF,DISC1,UNC5C,PODXL2,ARID5B,DCHS1,EFNA3,SPATA13,SDC3,WWC1,CDC42BPA,PKN3,FAT1,THBS4,MATN2,PLD1,CDH2,SEMA3A,SIX2,CXCR5,EPHA3,ID1,AMOTL1,CELSR3,DOCK1,RBFOX2,PSTPIP2,PLXNA2,NTRK3,NRXN1,DDR1,DOCK2,SEMA6A,CTNNA2,GPR15,LHX6,DAB2IP,PDE4D,PROS1,MET,DNAH5,SNAI2,DOCK8,SEMA6C,FER,EVL,FZD4,PTPN6,PREX1,WNT11,PRKCQ,SATB2,ATOH1,ATP1B1,RARRES2,JAM3,FGFR1,CENPV,CXCL10,NRG3,PTPRJ,KPNA3,PTK7,ITGA2,LAMB1,HGF,HOXB9,ROBO2,GRB14,EPS8,CMTM8,SELL,KIF5C,P2RY1,GAS6,OVOL2,PKN1,EPHB1,NEDD4,NEO1,SCN1B,PRKCD,KIAA0319,TNFRSF11A,SYK,FES,PARP9,TRPM4,VEGFC,VAV3,NR4A1,RAPGEF2,ASAP3,PALLD,PEAK1,GPLD1,RERE,GPR37,PTPRC,FGR,SLC7A5,BMP4,SLC1A5,ATP2B4 |
| 2.661e-12 | -26.65 | RIGGI_EWING_SARCOMA_PROGENITOR_UP | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_UP | 403 | 86 | 17377 | 1707 |
EPHA3,LANCL3,GRIK2,LMCD1,IL13RA1,KIAA1217,IKZF2,ABHD6,HMCN1,PCDH7,SCIN,CDS1,NELL2,AKAP7,KMO,REEP1,STEAP3,TMEM37,SLIT2,NTNG1,IL1RAP,FZD4,SLC39A8,FAM84A,TGFA,JPH1,PREX1,NLGN4X,RARRES2,FRK,TMEM132B,ZNF711,ENPP1,TCF7L1,TDO2,PRKCB,ZNF704,TNFSF15,TMEFF2,CTTNBP2,NR3C2,RRAGD,BCL11B,SV2B,LRFN5,FARP1,KLHL13,FZD8,ST6GAL1,C1orf226,PRSS35,CLSTN2,ISYNA1,EPHB1,SEL1L3,RNF141,ABCA5,GATA2,FLRT3,FAM107B,OPN3,TSPAN13,CADPS2,FAM84B,IGSF3,TRPM4,MSX1,MYO10,STAT4,COL4A4,PTPN13,CRIP2,SPATA13,MAFB,STEAP1,GLCE,GPR37,GALNT3,CACHD1,RIMKLB,FAT4,ADAMTS3,SLCO5A1,PGM2L1,DLG2,MYOM2 |
| 2.704e-12 | -26.64 | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | MSigDB lists | JAATINEN_HEMATOPOIETIC_STEM_CELL_UP | 285 | 68 | 17377 | 1707 |
FAM171B,PLA2G4A,PLEKHA5,ARHGAP22,UBTD2,TXNRD3,PLS3,KCTD15,CNKSR3,CHRDL1,ZNF521,MAP7,SCRN1,NAP1L3,BEND4,GATM,SCN3A,ALG10B,EBPL,SLC39A8,DEPTOR,MSRB3,ASPH,ZNF618,NT5DC2,GNAI1,BCL11A,ZNF711,HLF,SH3RF1,MAP9,PAM,MLLT3,SPOCK3,RUNX2,WDR17,RHOBTB1,ATP9A,SLC25A27,NKAIN2,SCD,ISYNA1,BEX2,GATA2,DSG2,VWDE,LIMCH1,SAMD13,MAST4,KIAA1211,HMGCR,B4GALT6,VAV3,KDM5B,SLC27A2,CRIM1,PLCB1,NEGR1,DPY19L2,DDAH1,DOCK7,PLAGL1,AKT3,SRD5A3,SH3BP4,LAPTM4B,SMYD3,CRISPLD1 |
| 2.840e-12 | -26.59 | breast-carcinoma-basal_(triple-negative)_carcinoma | COSMIC cancer mutations | breast-carcinoma-basal_(triple-negative)_carcinoma | 3035 | 403 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,THOC5,ACVR1,GRIK2,CNTNAP3,LDLR,VAMP8,PPFIBP2,STAT5B,CTBP2,ADAMTS6,PRKCA,KIAA1217,STK24,HECTD2,FBXO32,DNAH6,PMAIP1,RAP2A,ATRNL1,PPP2R2B,MAGEA6,VWA5A,THSD1,TSHR,NKX2-1,MEIS2,ACVR1C,KLHL3,TGFA,LRRK2,MEF2B,PRKAR2B,TNS1,FGF17,ACVR2B,SAV1,WIPF3,SH3RF1,ATP7B,RASGRF2,MAP9,ADRB1,BBC3,MAPK13,ERCC5,DIRAS1,SPRY4,NRP1,TMEFF2,SPOCK3,LPP,MEF2C,CARS,SEMA6B,SCN5A,LATS2,INPPL1,CELSR1,PTPRD,ITGA6,MLF1,GTF2IRD1,TJP1,FOXG1,MECOM,SYCP2,SLC7A11,CACNB2,MYC,RUNDC3B,PRKG1,CPXM2,CHRM3,ZNF385A,EPB41L5,PTCH2,STAT4,VLDLR,EFHC2,KIAA1324L,CALCRL,HIP1,ST6GALNAC3,CCDC85A,CDC42BPA,CACHD1,SH3GL2,CECR2,EMILIN2,MPP2,SQLE,HOXD13,SLFN5,TRPC3,CDH2,PLA2G4A,EPHA3,BTC,RASAL2,RHOD,GALNT12,ZNF311,PLXNA2,ABHD13,CHUK,DDR1,NELL2,TMEM53,TLR3,KMO,ALDOC,DAB2IP,RPL26L1,DNAH5,ZNF365,ATP6AP1L,SCN3A,FZD1,GAB2,GARS,RNF145,PDK1,FZD4,KCNH5,SHANK2,ADCY1,WNT11,PRKCQ,ATF3,FGFR1,MAGI3,ZNF711,IRS2,ARHGAP21,IKZF3,IQCH,PRKCB,TDO2,WWTR1,LAMB1,PLEKHG1,TNFSF15,GRB10,BMPR1A,CTTNBP2,HACE1,C1QTNF3,ROBO2,IGFBP6,CKAP2,FZD8,PLAG1,EPS8,PRSS35,HERC5,P2RY1,CREB5,PKN1,EPHB1,GDPD5,NEDD4,NEO1,GHR,SGK3,SPRY2,ZFP36L2,MED12L,PARP9,PFKFB4,MN1,BCL7A,VAV3,SH3BP2,PXN,RAPGEF2,TMEM126A,RASA3,UCHL3,GUCY1A2,GPLD1,PTPRC,NSD1,PCDHB7,TERT,GNAO1,AKT3,GRIN2D,MYOM2,BMP4,TNFRSF17,DDIT3,BTRC,FOXA1,TLL2,ATP1A3,FGF13,KIF5A,NDRG2,MGAT5B,FAM13A,DNER,KREMEN1,HMCN1,CHST10,CCNJ,RPS6KA2,LRRC6,CPVL,MARVELD2,LIN7A,TLN2,TLR4,ETV1,RASGRP1,PDGFRB,PRKACB,CYP1B1,LAMP3,DBN1,ABCC4,CAPN5,YAP1,CR2,ROR1,TMEM47,SGK2,RNF44,CRYBG3,EML1,TCF7L1,GPRC5B,NCAM2,P4HA2,CCDC146,TNFRSF1A,PIK3C2B,TNFSF4,MAGI2,MLLT3,KCNV1,PRKAA2,BCL11B,RUNX2,STXBP5L,JDP2,SETBP1,RASL11B,PHGDH,SATB1,PGAP1,FHOD3,SPIRE1,RNF180,OTUD1,NUMBL,IGF1R,BCHE,HS3ST5,FAM107B,LRP6,NOS3,PAK1,DPYSL5,FGFR4,MID2,IL17RD,PCDH10,SPATA13,MAFB,DUSP9,WWC1,SDK1,PRDM1,B4GALNT3,STEAP1,NEGR1,MAPKAPK2,HEYL,RAI14,PTPRN2,EGFL7,PLD1,FNBP1L,SFN,CXCR5,DMXL2,CFH,HECW2,TDRKH,NTRK3,SEZ6L2,TNKS1BP1,RADIL,PIBF1,TBC1D19,COL22A1,SETDB2,TACC2,C12orf60,ZNF521,ZDHHC23,BCL6,ACVR2A,CLVS2,MET,SCN2A,NTNG1,IGFBP3,GLI1,DPP10,INTU,PHLDB2,TMEM67,PTPRU,PTPN6,THSD4,FGF12,ACO1,CD40,FRK,BCL11A,RANBP2,NRG3,PTPRJ,PTK7,EIF4EBP1,ITGA2,DUSP19,DISP1,CYP2U1,RNF130,SEPT5,LIFR,CNTN1,HEY1,PCDH18,LPAR2,BMPR2,KLHL13,ARHGEF11,GRB14,TSPAN15,RUSC2,REL,APBB1,LRP4,TNFSF13B,SSX1,CLSTN2,FAM117B,RASD1,PRDM8,IGF2BP2,COL4A5,USP30,PPP2R3A,FOXP2,FSD1,CHN2,PRKCD,RASD2,EHD3,SGK1,RRAS2,SYK,TNFRSF11A,DUSP1,RIN2,CARD6,PPP1R3D,USP2,HNF4G,CRIM1,NUAK2,PRICKLE1,MARS,AGAP2,C3orf70,PALLD,TLR6,MGMT,MAP1B,DKK1,EBF1,GPR37,CD37,DOCK7,FAT4,FBN1,MPP7,RND3,MAP2K6,THSD7B,KIAA0513,DLG2,KIF21A,GEM,TBC1D4,FILIP1,ABCG1 |
| 2.840e-12 | -26.59 | basal_(triple-negative)_carcinoma | COSMIC cancer mutations | basal_(triple-negative)_carcinoma | 3035 | 403 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,THOC5,ACVR1,GRIK2,CNTNAP3,LDLR,VAMP8,PPFIBP2,STAT5B,CTBP2,ADAMTS6,PRKCA,KIAA1217,STK24,HECTD2,FBXO32,DNAH6,PMAIP1,RAP2A,ATRNL1,PPP2R2B,MAGEA6,VWA5A,THSD1,TSHR,NKX2-1,MEIS2,ACVR1C,KLHL3,TGFA,LRRK2,MEF2B,PRKAR2B,TNS1,FGF17,ACVR2B,SAV1,WIPF3,SH3RF1,ATP7B,RASGRF2,MAP9,ADRB1,BBC3,MAPK13,ERCC5,DIRAS1,SPRY4,NRP1,TMEFF2,SPOCK3,LPP,MEF2C,CARS,SEMA6B,SCN5A,LATS2,INPPL1,CELSR1,PTPRD,ITGA6,MLF1,GTF2IRD1,TJP1,FOXG1,MECOM,SYCP2,SLC7A11,CACNB2,MYC,RUNDC3B,PRKG1,CPXM2,CHRM3,ZNF385A,EPB41L5,PTCH2,STAT4,VLDLR,EFHC2,KIAA1324L,CALCRL,HIP1,ST6GALNAC3,CCDC85A,CDC42BPA,CACHD1,SH3GL2,CECR2,EMILIN2,MPP2,SQLE,HOXD13,SLFN5,TRPC3,CDH2,PLA2G4A,EPHA3,BTC,RASAL2,RHOD,GALNT12,ZNF311,PLXNA2,ABHD13,CHUK,DDR1,NELL2,TMEM53,TLR3,KMO,ALDOC,DAB2IP,RPL26L1,DNAH5,ZNF365,ATP6AP1L,SCN3A,FZD1,GAB2,GARS,RNF145,PDK1,FZD4,KCNH5,SHANK2,ADCY1,WNT11,PRKCQ,ATF3,FGFR1,MAGI3,ZNF711,IRS2,ARHGAP21,IKZF3,IQCH,PRKCB,TDO2,WWTR1,LAMB1,PLEKHG1,TNFSF15,GRB10,BMPR1A,CTTNBP2,HACE1,C1QTNF3,ROBO2,IGFBP6,CKAP2,FZD8,PLAG1,EPS8,PRSS35,HERC5,P2RY1,CREB5,PKN1,EPHB1,GDPD5,NEDD4,NEO1,GHR,SGK3,SPRY2,ZFP36L2,MED12L,PARP9,PFKFB4,MN1,BCL7A,VAV3,SH3BP2,PXN,RAPGEF2,TMEM126A,RASA3,UCHL3,GUCY1A2,GPLD1,PTPRC,NSD1,PCDHB7,TERT,GNAO1,AKT3,GRIN2D,MYOM2,BMP4,TNFRSF17,DDIT3,BTRC,FOXA1,TLL2,ATP1A3,FGF13,KIF5A,NDRG2,MGAT5B,FAM13A,DNER,KREMEN1,HMCN1,CHST10,CCNJ,RPS6KA2,LRRC6,CPVL,MARVELD2,LIN7A,TLN2,TLR4,ETV1,RASGRP1,PDGFRB,PRKACB,CYP1B1,LAMP3,DBN1,ABCC4,CAPN5,YAP1,CR2,ROR1,TMEM47,SGK2,RNF44,CRYBG3,EML1,TCF7L1,GPRC5B,NCAM2,P4HA2,CCDC146,TNFRSF1A,PIK3C2B,TNFSF4,MAGI2,MLLT3,KCNV1,PRKAA2,BCL11B,RUNX2,STXBP5L,JDP2,SETBP1,RASL11B,PHGDH,SATB1,PGAP1,FHOD3,SPIRE1,RNF180,OTUD1,NUMBL,IGF1R,BCHE,HS3ST5,FAM107B,LRP6,NOS3,PAK1,DPYSL5,FGFR4,MID2,IL17RD,PCDH10,SPATA13,MAFB,DUSP9,WWC1,SDK1,PRDM1,B4GALNT3,STEAP1,NEGR1,MAPKAPK2,HEYL,RAI14,PTPRN2,EGFL7,PLD1,FNBP1L,SFN,CXCR5,DMXL2,CFH,HECW2,TDRKH,NTRK3,SEZ6L2,TNKS1BP1,RADIL,PIBF1,TBC1D19,COL22A1,SETDB2,TACC2,C12orf60,ZNF521,ZDHHC23,BCL6,ACVR2A,CLVS2,MET,SCN2A,NTNG1,IGFBP3,GLI1,DPP10,INTU,PHLDB2,TMEM67,PTPRU,PTPN6,THSD4,FGF12,ACO1,CD40,FRK,BCL11A,RANBP2,NRG3,PTPRJ,PTK7,EIF4EBP1,ITGA2,DUSP19,DISP1,CYP2U1,RNF130,SEPT5,LIFR,CNTN1,HEY1,PCDH18,LPAR2,BMPR2,KLHL13,ARHGEF11,GRB14,TSPAN15,RUSC2,REL,APBB1,LRP4,TNFSF13B,SSX1,CLSTN2,FAM117B,RASD1,PRDM8,IGF2BP2,COL4A5,USP30,PPP2R3A,FOXP2,FSD1,CHN2,PRKCD,RASD2,EHD3,SGK1,RRAS2,SYK,TNFRSF11A,DUSP1,RIN2,CARD6,PPP1R3D,USP2,HNF4G,CRIM1,NUAK2,PRICKLE1,MARS,AGAP2,C3orf70,PALLD,TLR6,MGMT,MAP1B,DKK1,EBF1,GPR37,CD37,DOCK7,FAT4,FBN1,MPP7,RND3,MAP2K6,THSD7B,KIAA0513,DLG2,KIF21A,GEM,TBC1D4,FILIP1,ABCG1 |
| 3.204e-12 | -26.47 | GO_CELL_DEVELOPMENT | MSigDB lists | GO_CELL_DEVELOPMENT | 1366 | 212 | 17377 | 1707 |
EXPH5,UGT8,ACVR1,KIF5A,GATA3,ENAH,CEBPA,DNER,CACNB4,RAC3,TRPS1,SKI,TGFBR3,RPS6KA2,EOMES,MARVELD2,ITGB3,GSTM3,CTTN,PACSIN1,TLR4,ETV1,SLIT2,PDGFRB,NKX2-1,ATL1,ITGB7,GPM6A,DCC,ANK2,LRRK2,FEZ1,ARHGEF26,TSKU,INHBC,GSN,NCKAP1L,MAP2,BMP1,SEMA3C,TMOD2,UNC5B,NRP1,TPM1,MAGI2,MEF2C,TYRO3,BCL11B,EFNB2,LATS2,SEMA6B,LRFN5,RUNX2,FN1,BVES,GABRB2,OPHN1,LAMC3,TJP1,CHSY1,SLC1A3,PHGDH,CHD5,FHOD3,CHN1,NUMBL,CNTN4,SEMA4F,FRY,PDZD7,GATA2,FLRT3,PRKG1,LRP6,GRIP1,NCAM1,STXBP1,ZNF385A,EPB41L5,DPYSL5,PAK1,BDNF,DISC1,UNC5C,SLITRK2,MSTN,VLDLR,ARID5B,EFNA3,FHL2,OBSCN,SLITRK5,PRDM1,TAF4B,CLN5,BAIAP2,MFSD2A,HEYL,THBS4,MATN2,INHBE,CLMN,SEMA3A,NKX2-8,SMYD3,SFN,SIX2,EPHA3,TFCP2L1,NBL1,ID1,IL15,CELSR3,ST14,RBFOX2,PLXNA2,COL18A1,NRXN1,RADIL,PPP1R9A,SEMA6A,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,BCL6,DAB2IP,PDE4D,POU2F2,SERPINH1,MET,ZNF488,HSPA2,NTNG1,SEMA6C,SNAI2,FER,MYLK3,EVL,FZD4,NKX3-2,PTPN6,ADCY1,SATB2,WNT11,PRKCQ,VIM,AMIGO1,ATOH1,PYGO1,JAM3,FGFR1,GJC1,SMAD3,LAMB1,PTPRS,KLF5,HGF,BMPR1A,ATG5,LIFR,COBL,CTNND2,HEY1,CNTN1,WASF3,FARP1,ROBO2,BMPR2,LRP4,APBB1,KIF5C,PRDM8,OVOL2,EPHB1,GDPD5,BMP6,COL27A1,NEDD4,NEO1,NKX6-1,LRRC55,LRRN1,SCN1B,BHLHA15,TFAP2A,ACTA2,SGK1,FIG4,MSX1,RAPGEF2,MEI1,FERMT2,PALLD,FNDC3A,PEAK1,MAP1B,HEG1,DKK1,RERE,PTPRC,DPY19L2,DOCK7,MYADM,FAT4,GNAO1,XBP1,LRRK1,BMP4,SHOX2,FOXA1 |
| 3.386e-12 | -26.41 | ovary | COSMIC cancer mutations | ovary | 15237 | 1572 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,DSTN,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,FZD8,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,NHP2,CA8,EYA4,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,BARX1,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 3.938e-12 | -26.26 | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | MSigDB lists | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | 262 | 64 | 17377 | 1707 |
CREB3L2,MYO1D,TSPAN15,RHOBTB1,ST14,SEC24D,ZNF25,RHPN2,TJP1,SLC1A3,KIAA1217,EYA4,FKBP11,EPDR1,SYDE2,FOXP2,EPCAM,ASNS,IGF1R,UNC13B,TACC2,BHLHA15,NBEA,TMED9,TSPAN13,FKBP14,CKAP4,SNAI2,INTU,GPM6A,USP2,ERGIC1,DUSP9,SDC3,YAP1,PRICKLE1,AIG1,PRDM1,CCNG1,FNDC3A,ASPH,DSP,SMPDL3B,NEGR1,PYCR1,CEBPB,IRS2,ENTPD1,ENPP1,ICA1,TERT,WFS1,MATN2,XBP1,SLC7A5,UACA,LAPTM4B,SH3BGRL2,TNFRSF17,TANC2,MBOAT2,ATP2B4,FILIP1,DENND5B |
| 4.173e-12 | -26.20 | BENPORATH_SUZ12_TARGETS | MSigDB lists | BENPORATH_SUZ12_TARGETS | 968 | 162 | 17377 | 1707 |
SIDT1,FGF13,SYT12,MCOLN3,GATA3,ANKRD18A,MGAT5B,DNER,CACNB4,ABHD6,DACH2,PLS3,PPM1E,EOMES,KCNAB1,ZFYVE28,GSTM3,HRK,TMEM132E,THSD1,SLIT2,RASGRP1,NKX2-1,CYP1B1,EIF4E3,DCC,WLS,GJB2,FAM84A,NFIA,ELMOD1,FEZ1,KCND3,TRIM9,HLF,CCBE1,RASGRF2,ADRB1,TMOD2,DLX2,UNC5B,TMEFF2,NRP1,NEUROG2,MLLT3,SPOCK3,HS6ST3,KCNV1,LRFN5,SV2B,GNG12,LGALS3,TBC1D1,CYP2J2,STXBP6,RIMKLA,FAM81A,FOXG1,HPCAL4,MECOM,SEMA4F,SLC30A4,GATA2,SCARF2,PRKG1,ST8SIA1,NCAM1,BARX1,COL9A2,GFRA1,CEBPD,SNX7,NDUFA4L2,DPYSL5,RAX,ANKRD20A2,UNC5C,SLITRK2,KCNQ3,SLC27A2,RAPGEF4,TCEA3,EFNA3,SLITRK5,MAFB,SHISA2,PLCB1,CSF1,RAB31,HOXD13,NKX2-8,SIX2,EML5,NBL1,PCSK1N,XYLT1,PLXNA2,RGS20,OTX1,MAPK4,NTRK3,CBLN1,CYP26A1,COL25A1,LHX6,ALDH1L1,ZNF365,GATM,ANKRD18B,ANKRD20A3,PTPRU,SOX21,NKX3-2,TCEAL3,WNT11,ATF3,ATOH1,BATF3,HTR7,ZNF711,CAMK2N1,MSC,IKZF3,CCNA1,RGS10,HS3ST3B1,SUSD4,MID1,CTNND2,HEY1,EPS8,CLSTN2,COL4A5,EPHB1,KCNC4,COL27A1,HOPX,NKX6-1,AFF2,GHR,GFI1,SMAD6,TNFRSF11A,SLC40A1,MSX1,CACNA1E,GRID1,PRICKLE1,GUCY1A2,ILDR2,ZIC1,DKK1,MKX,DPY19L2,DDAH1,FBN1,SLCO5A1,GRIN2D,PAX9,SHOX2,FOXA1,TLL2 |
| 5.168e-12 | -25.99 | kidney | COSMIC cancer mutations | kidney | 15842 | 1618 | 17385 | 1698 |
ARHGAP26,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,WDR17,CKAP2,FZD8,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,NOS3,GPR176,ANKRD20A2,RAX,IL17RD,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 5.416e-12 | -25.94 | regulation of cell communication | biological process | GO:0010646 | 3548 | 451 | 17256 | 1658 |
ARHGAP26,ACVR1,DUSP8,LGR4,GRIK2,VAMP8,GATA3,CTBP2,CHAC1,PRKCA,ABHD6,RAC3,EYA4,STK24,NOS1AP,SKI,TYMP,TGFBR3,PMAIP1,ZFYVE28,RAP2A,KCNS3,CHRDL1,RCAN3,NKX2-1,ACVR1C,WISP3,WLS,TGFA,LRRK2,DEPTOR,ACVR2B,FGF17,GPC6,ARHGEF26,GNAI1,ENPP1,SH3RF1,CCBE1,RASGRF2,PLK2,ADRB1,BMP1,ARHGAP28,BBC3,TMOD2,INPP5F,DIRAS1,SPRY4,NRP1,UNC5B,SPART,MEF2C,LATS2,ITGA6,OPHN1,BTBD9,TNFRSF10C,SLC1A3,TNFRSF19,CHD5,GAS1,MYORG,MECOM,IL17D,CHN1,CNTN4,RALGPS2,PIK3AP1,MYC,FLRT3,C1QL4,PRELID1,SREBF1,SRGAP1,STXBP1,RIMS2,GPR161,ZNF385A,RNF152,HMGCR,PTCH2,RPL26,BDNF,DISC1,RAPGEF4,RYR2,HIP1,PEX5L,SHISA2,SNAP25,TAF4B,PLCB1,FAM162A,SH3GL2,PMEPA1,ADAMTS3,PELI2,THBS4,MPP2,INHBE,SPRED3,IQSEC2,CDH2,EPHA3,NBL1,BTC,RASAL2,RHOD,GPR65,RGS20,CHUK,GRK6,TMEM170B,NRXN1,DDR1,TIAM2,TLR3,KMO,CNKSR3,DACT1,MAGEA3,SHF,DAB2IP,MARCKS,PDE4D,FZD1,FZD4,ADM2,PFKFB2,SHANK2,PREX1,NLGN4X,ATF3,CBY1,PRKCQ,WNT11,FGFR1,MAGI3,SNCA,IRS2,CXCL10,ARHGAP21,PRKCB,WFS1,APELA,WWTR1,ASIC1,PLEKHG1,MAP3K21,TNFSF15,GRB10,BMPR1A,MAPK10,MID1,CGB2,FARP1,C1QTNF3,EDA2R,IGFBP6,BACE1,FZD8,EPS8,BIK,ARL2,PSD3,GAS6,P2RY1,PKN1,EPHB1,RGS7,NDFIP2,KCNC4,GDPD5,TPD52L1,TSPAN17,PHLDA2,NEDD4,NEO1,RGS17,MCF2L,GHR,SGK3,RALGAPA2,DYNC2H1,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,PARP9,TRPM4,VEGFC,VAV3,SH3BP2,PXN,ARAP2,ARHGEF28,GSTM2,PTPN13,CACNA1E,MCF2L2,RAPGEF2,RASA3,GAREM1,RACK1,SKAP1,ZIC1,GPLD1,PTPRC,TRIB3,FGR,TERT,AKT3,XBP1,MCC,PCGF2,GRIN2D,BMP4,LRRK1,SHOX2,DDIT3,ATP2B4,FOXA1,BTRC,TPT1,CACNG3,FGF13,TRIM16,SYT12,LMCD1,NDRG2,HDGFL3,ITPR2,ABAT,FAM13A,KREMEN1,F3,GSDME,ARHGEF10L,SIPA1L2,AKAP7,ITGB3,HRK,EPHB6,CTTN,PTPRE,MYRIP,ENO1,TLR4,SLIT2,PRKACB,PDGFRB,RASGRP1,CYP1B1,DBN1,CD55,ATF4,GCNT2,SESN2,SKAP2,ANK2,JPH1,YAP1,ROR1,PLEKHA1,SESN1,TSKU,INHBC,GSN,TCF7L1,KCNMB4,GPRC5B,INSIG1,HPSE,ERN1,TNFRSF1A,OXTR,DLX2,PPARGC1A,TNFSF4,MAGI2,MLLT3,RRAGD,PRKAA2,TYRO3,RGS16,RUNX2,FN1,STXBP5L,LGALS3,RHOBTB1,UBASH3B,RASL11B,SORBS3,CHSY1,PFN2,IL18R1,DOK5,DDIT4,EFEMP1,CA2,IGF1R,BCHE,GATA2,PDE10A,LRP6,INAVA,BNIP3,FBXL2,BARX1,NOS3,PAK1,FGFR4,ATP5IF1,MID2,RHOQ,MSTN,SH2D2A,HOMER2,SPATA13,WWC1,STRADB,OBSCN,DUSP9,PDE8A,PRDM1,HERPUD1,BAIAP2,MAPKAPK2,GRIK4,RIPOR2,CSF1,HEYL,SH3BP4,EGFL7,SEMA3A,SFN,PRKN,SORBS1,ID1,NEK10,AVPI1,AKAP5,IL15,ARHGAP22,NTRK3,PIBF1,PPP1R9A,CBLN1,CYP26A1,UNC13B,BCL6,ACVR2A,WWC2,MET,SNAI2,GLI1,CTH,IGFBP3,INTU,FER,PRAME,NOP53,PTPN6,FGF12,RNF125,GSTO1,SYNJ2BP,CD40,CAMK2N1,SMAD3,NRG3,PTPRJ,GBP1,RBPMS2,ITGA2,RGS10,DUSP19,PTPRS,HGF,DISP1,SEPT5,LIFR,CTNND2,HEY1,ARFGEF3,TENM1,TNIK,DYRK3,SLC6A9,NECAB2,IL32,BMPR2,TSPAN15,GRB14,ARHGEF11,PAK5,REL,LRP4,CMTM8,NLRP14,TNFSF13B,CLSTN2,NOTUM,BMP6,ARHGAP44,MCU,SYDE2,NKX6-1,RAB11FIP5,CHN2,MAP1A,PRKCD,STC2,RASD2,AFAP1L2,PCK2,IQGAP3,TNFRSF11A,TESPA1,SYK,PCSK6,DUSP1,RAB3B,MSX1,KDM5B,CYTH3,SYBU,LITAF,ASAP3,GRID1,PRICKLE1,AGAP2,ARHGAP32,TLR6,SMPDL3B,DKK1,GPR37,ICA1,MYADM,TMEM237,EDA,NACC2,FBN1,GCSAM,MPP7,PRCP,MAP2K6,UACA,MAP3K20 |
| 5.560e-12 | -25.92 | mouth | COSMIC cancer mutations | mouth | 9240 | 1035 | 17385 | 1698 |
ARHGAP26,TRIM16L,GRIK2,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,POU3F3,DCC,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,ADRB1,ERCC5,DIRAS1,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,TJP1,BTBD9,FOXG1,BBS9,CHN1,FRY,APLF,FLRT3,SRGAP1,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,KCNQ3,ARID5B,FASN,HIP1,SNAP25,ZBBX,ARRDC4,SPATA7,TEX15,RIMKLB,GSTO2,CLMN,LAPTM4B,CDH2,DOCK9,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,ZNF365,DNAH5,MYT1,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,DSP,ASPH,ZNF618,MAGI3,ENTPD1,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,WDR17,GCAT,ESRP1,PLAG1,UBAC2,CBS,SLC12A6,EPHB1,ZNF219,LRRN1,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,MN1,AK4,RASA3,NSD1,PCDHB7,PLOD2,NEK11,PIP5KL1,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,PHACTR3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,TMEM200C,CR2,TTC22,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,ERN1,TC2N,HS6ST3,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,ZBTB38,ZNF440,FRAS1,HS3ST5,LRP6,ADCY6,MED7,FAR2,VGLL4,CKAP4,DPYSL5,MGAT4B,GPSM1,OBSCN,SLITRK5,SDK1,KHDRBS2,BAIAP2,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,DOCK1,NTRK3,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,HRASLS,INTU,CSN2,TDRD3,PRDM13,RNF125,VIM,RNF217,PTPRS,MBOAT2,CTNND2,BMPR2,MCTP2,RASD1,SLC35F1,TFAP2A,GTF2F2,TSC22D1,SGK1,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FERMT2,PRICKLE1,PALLD,SMPDL3B,HOMER3,DDAH1,CD37,DOCK7,FBN1,SLC1A5,KIF1B,CACNA2D1,ZNF235,FAM171B,LGR4,LDLR,PRKCA,TRPS1,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,ERGIC1,ACVR1C,KLHL3,FAM84A,ZDHHC14,GNAI1,SH3RF1,ENPP6,MAPK13,DSEL,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,LRRC49,APBA1,GAS1,MTUS1,ABLIM1,RALGPS2,NOVA2,C1QL4,PRKG1,SREBF1,CPXM2,FAM155A,PRR16,COL9A2,PTCH2,DISC1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,SMYD3,NBL1,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,SHF,GAB2,B3GALT1,SHANK2,PREX1,NLGN4X,SATB2,ATOH1,ATP1B1,ZNF711,IKZF3,CCNA1,BMPR1A,COBL,PURG,STON2,MID1,HACE1,MYO1D,EPS8,PRSS35,HERC5,KIF5C,RASSF8,LRRC55,AFF2,DYNC2H1,ERRFI1,TBC1D9,VAV3,SLC40A1,ALDH2,PXN,SH3BP2,PTPN13,GPR137C,TERT,MCC,SVIL,DDIT3,ACSL1,UGT8,PTPN21,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,LGI2,EPCAM,PPM1E,SIPA1L2,ANKFN1,CNNM2,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,TNK2,SESN2,JPH1,TMEM47,SGK2,GSN,GPRC5B,FAM114A2,CCDC169,OXTR,PPARGC1A,MAGI2,PCSK5,GPR63,SV2B,MOCOS,ZNF395,RHOBTB1,STXBP6,FBXO4,CHADL,FAM81A,SPINK5,PCDHB14,EEF2,LIMCH1,CAND2,ZNF629,PCDH10,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,KIAA0355,NCR3LG1,FAT1,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,ARHGAP22,HECW2,COL18A1,PIBF1,SCIN,PDZD8,PPFIBP1,KAZN,ACVR2A,TMEM120B,SEMA6C,PRAME,PTPRU,PTPN6,MVD,C3orf52,AMIGO1,CD40,ZNF569,ARMC4,CAMK2N1,EIF4EBP1,TMPRSS9,RNF130,MAST1,ARHGEF11,TSPAN15,ARL15,SSX1,TNFSF13B,IGF2BP2,COL4A5,OVOL2,SEL1L3,BMP6,SYDE2,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,MARCH3,AFAP1L2,CARD6,HNF4G,CRIM1,ASAP3,GALNT14,TLR6,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,UACA,IL9R,NPHP1,DOC2A,PDE1B,FLVCR2,PRSS12,AASS,DNAJC3,STAT5B,DOCK3,CA8,NOS1AP,EYA4,EPDR1,TGFBR3,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,GJB2,TGFA,MSRB3,F12,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,SYCP2,ZIC5,LOXL4,NCAM1,TSPAN9,GLIS1,ZNF518B,GFRA1,FMNL2,CHRM3,LRP12,HMGCR,FADS1,MYO10,STAT4,RYR2,PLS1,TMCO3,SH3GL2,EMILIN2,SPRED3,NUDT10,BTC,ZNF516,DNM3,GALNT6,FAM131C,GALNT12,MYO1B,RGS20,LRRCC1,IL13RA1,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,GPRIN1,DACT1,COL25A1,CNKSR3,RTKN2,SYNGR3,JAKMIP3,RAB27B,FAM155B,DOCK8,SCN3A,SSH3,GARS,RNF145,KCNH5,RAB38,TTC28,FGFR1,IQCH,PLEKHG1,PAM,RCN3,DBP,KLHL31,SERINC5,TMEM132C,ROBO2,IPO5,NKAIN2,P2RY1,PKN1,COL27A1,NEO1,GAS2L3,NPTXR,MYO6,FES,BCL7A,CLYBL,RAPGEF2,MCF2L2,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,AKT3,OSBPL5,SLCO5A1,HK1,DOCK6,FOXA1,DCBLD1,TPT1,NBPF4,FAM227A,SYT12,FHDC1,LILRB1,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,SLC3A2,GDPD1,BATF,MAP2,GNB4,TECPR2,TNFRSF1A,TIGD4,PIK3C2B,PRKAA2,ITPRIP,RASL11B,SETBP1,MLC1,PGAP1,IL18R1,HSPA12B,EFEMP1,IGF1R,SEMA4F,ABCA5,PDE10A,SAMD11,BNIP3,PTPRCAP,FBXL2,SLCO4C1,CHSY3,FGFR4,PAK1,UNC5C,RNF170,SLC27A2,SPATA13,TCEA3,TMTC4,PPFIA4,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,MFSD2A,HEYL,SIX2,MME,AVPI1,CFH,XYLT1,OR51B4,FAM198B,LPIN3,SEZ6L2,PCLO,CYP26A1,TBC1D19,SLC22A17,LHX6,ZDHHC6,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,TMEM67,THSD4,RARRES2,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,KCNG1,ABI3,ITGA2,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,IL32,GRB14,RUSC2,NLRP14,APBB1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,KIAA1211,DLGAP1,MICAL2,NUAK2,FNDC3A,TGDS,FAT4,ZNF474,DLG2,ZNF808,PAX9,SLC22A15,THAP10,TBC1D4,FILIP1,CGN,MYCBP2,ACVR1,PPP4R4,SIDT1,DUSP8,ATP8A1,PPFIBP2,ENAH,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,SLC16A2,CHRDL1,ATRNL1,GSTM3,BEND4,SP140,VWA5A,PACSIN1,MAGEA6,TBC1D8,DCDC1,EML6,KLHL4,DEPTOR,TNS1,ACVR2B,ARHGEF26,GPC6,AHRR,RASGRF2,ENTPD7,CCBE1,PLK2,SEMA3C,UNC5B,TANC2,LZTS1,INPPL1,EHHADH,CELSR1,ZHX3,PTPRD,GABRB2,SCN8A,OLAH,OPHN1,SLC25A27,GTF2IRD1,WDFY4,TNFRSF10C,SLC1A3,ISYNA1,CHD5,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,MPDZ,SLC16A9,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,DAGLA,PMEPA1,IQSEC2,AMPD1,ACSM3,EPHA3,TBKBP1,PCSK1N,AMOTL1,ELOVL4,RNF144A,ZNF311,OTX1,CHUK,ZNF827,NELL2,NBEA,NAP1L3,SERPINH1,ATP6AP1L,PDK1,SOX21,TBC1D16,HTR7,ZNF396,PRKCB,KLF5,CTTNBP2,NR3C2,KCTD1,DENND5B,ANKRD13D,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,RALGAPA2,SLC6A15,GFI1,SEPT3,ARAP2,SYNPO2,CACNA1E,GUCY1A2,ZIC1,FGR,NUTM2A,TUFT1,PGM2L1,MYOM2,GRIN2D,B4GALT7,OCLN,ATP1A3,SLC43A1,EXPH5,MVK,HEBP1,ABAT,RBM11,KREMEN1,CEP85L,CYP51A1,ARHGEF10L,RTN1,LRRC6,AKAP7,POF1B,SLC2A12,PCOLCE2,OR2W3,FANK1,PTPRE,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,ROR1,RNF44,EML1,TMEM132B,AK1,NCAM2,NCOA7,FN1,SEC24D,RIMKLA,LAMC3,ATP6V1E2,SATB1,PHGDH,CD7,FAM107B,EBF4,NOS3,RAX,IL17RD,GPR176,PARD3B,DUSP9,WWC1,PRDM1,B4GALNT3,GLCE,FCHO2,RAI14,HK2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,CELSR3,PLEKHA5,MORC4,TDRKH,BCL6B,DOCK2,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,POU2F2,MET,WWC2,ZNF460,HSPA2,PHLDB2,TES,SLC39A8,SYNJ2BP,DOCK5,TTLL7,WARS,TPK1,MSC,LMLN,BACH2,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,LRP4,NSUN6,CLSTN2,CUEDC2,NKX6-1,GTSF1,DSG2,KIAA0319,IQGAP3,RRAS2,RIN2,RAB3B,NR4A1,GRID1,OGDHL,PRRG1,MEI1,PHACTR2,AGAP2,MARS,ARHGAP32,ZFPM2,RERE,MAP1B,ADAMTS17,NACC2,MPP7,MAP2K6,THSD7B,SLC7A5,KIF21A,GEM,MMP16 |
| 7.674e-12 | -25.59 | PASINI_SUZ12_TARGETS_DN | MSigDB lists | PASINI_SUZ12_TARGETS_DN | 304 | 70 | 17377 | 1707 |
CGN,AMOTL1,PKP2,NCS1,F3,IDI1,MARVELD2,MARCKS,SERPINH1,CPE,PERP,IGFBP3,CYP1B1,DBN1,PHLDB2,TUBA1A,TMEM43,NR6A1,WLS,TES,VIM,TMEM47,DSP,IRS2,GSN,ZNF266,PDLIM3,BACH2,GBP1,PLK2,WWTR1,BMP1,SEMA3C,GRB10,TPM1,LPP,GNG12,FARP1,FN1,CD276,KIF5C,SCD,COL4A5,TNFRSF19,EFEMP1,MYC,FLRT3,GHR,FAM107B,ACTA2,FAM84B,ERRFI1,RRAS2,TSPAN9,DUSP1,PDLIM7,BDNF,PRICKLE1,CCNG1,PALLD,STEAP1,MYADM,PLOD2,RND3,CLDN12,CSF1,BMP4,CDH2,PKIA,SFN |
| 8.224e-12 | -25.52 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm | 779 | 136 | 17385 | 1698 |
ARHGAP26,THOC5,ATP8A1,NPM1,CADM2,SYT14,DNER,HMCN1,SLCO3A1,FSTL5,PCDH7,PLS3,PPM1E,TGFBR3,KCNN2,ZFYVE28,DNAH6,PPFIA2,ANKFN1,ATRNL1,LIN7A,SLC2A12,TMEM132E,TSHR,FANK1,SLIT2,PRKACB,EML6,DCDC1,COL4A3,DCC,KCND3,ROR1,TCERG1L,SESN1,SERGEF,GPC6,ENTPD7,SERPINI1,SPRY4,NRP1,TANC2,MAGI2,MLLT3,HS6ST3,UST,CELSR1,STXBP5L,RHOBTB1,UBASH3B,ZCCHC24,RIMKLA,SETBP1,GALNT13,CHSY1,FHOD3,CA2,IGF1R,BACE2,GATA2,FRAS1,FAM107B,CADPS2,FAM155A,LRP12,UNC5C,ARID5B,RYR2,ST6GALNAC3,PEX5L,SDK1,B4GALNT3,PLCB1,KHDRBS2,MBNL2,NEGR1,CACHD1,GRIK4,PLEKHH2,SH3GL2,KIAA0355,RAB31,PTPRN2,SEMA3A,CDH2,DIRC2,DMXL2,EPHA3,HECW2,SLC7A2,SPATS2L,KIF21B,DDX60L,PCLO,DOCK2,COL22A1,KCTD15,COL25A1,KAZN,FHIT,FER,NECAB1,PFKFB2,KCNH5,ACO1,NLGN4X,FRK,NRG3,POPDC3,RBPMS2,GRB10,CTTNBP2,MID1,ANO10,MYO1D,PSD3,NKAIN2,CLSTN2,GDPD5,MICAL2,ARHGEF28,CLYBL,ESRRG,SYBU,GRID1,ZFPM2,PALLD,ILDR2,EBF1,ADAMTS17,DDAH1,L3MBTL4,TERT,THSD7B,CERS1,BTRC |
| 8.264e-12 | -25.52 | HELLER_HDAC_TARGETS_UP | MSigDB lists | HELLER_HDAC_TARGETS_UP | 298 | 69 | 17377 | 1707 |
PCSK1N,DNM3,SORBS1,CFH,AASS,ENAH,IL13RA1,ABAT,SEZ6L2,CDR2L,PPM1E,IDI1,LRRC6,ALDOC,BCL6,CTTN,HSPA2,LAMP3,DBN1,FER,GPM6A,TUBA1A,SLC25A28,PRKAR2B,EFHC1,TMEM47,COTL1,CXCL10,GSN,HPSE,PRKCB,PLK2,RCN3,MAOA,SERPINI1,ZBTB20,DLX2,MEF2C,FN1,CHCHD7,ITGA6,MLF1,ZCCHC24,BLVRB,GPSM2,SFXN3,PFN2,RUNDC3B,SGK3,TSPAN13,TSPAN12,NCAM1,PDLIM7,FGFR4,MSX1,KDM5B,GSTM4,MGST3,CRIP2,SMARCD3,ZBBX,GLCE,BEX4,MAPKAPK2,WDR19,TUFT1,DOCK6,CSRP2,DOCK9 |
| 8.567e-12 | -25.48 | neuron differentiation | biological process | GO:0030182 | 966 | 158 | 17256 | 1658 |
UGT8,KIF5A,MCOLN3,GATA3,HDGFL3,ENAH,PRKCA,RAC3,STK24,GSDME,SKI,EOMES,CTTN,PACSIN1,ETV1,SLIT2,NKX2-1,ATL1,GPM6A,ATF4,DCC,LRRK2,FEZ1,TSKU,NCAM2,NCKAP1L,MAP2,SEMA3C,DLX2,UNC5B,NRP1,NEUROG2,MEF2C,BCL11B,EFNB2,LRFN5,RUNX2,PTPRD,GABRB2,OPHN1,SLC1A3,PHGDH,SPINK5,FOXG1,CHD5,DOK5,DDIT4,CHN1,NUMBL,CNTN4,SEMA4F,FRY,PDZD7,GATA2,FLRT3,PRKG1,LRP6,GRIP1,NCAM1,STXBP1,GFRA1,LRP12,PAK1,DPYSL5,UNC5C,BDNF,SLITRK2,VLDLR,EFNA3,SLITRK5,PRDM1,CLN5,BAIAP2,ADGRB3,SH3GL2,MATN2,CLMN,NKX2-8,SEMA3A,SHTN1,EPHA3,NBL1,ID1,CELSR3,RBFOX2,PLXNA2,NTRK3,NRXN1,DDR1,SEMA6A,PPP1R9A,CBLN1,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,ZNF521,DAB2IP,ZNF365,NTNG1,SEMA6C,FZD1,GAB2,EVL,FZD4,SHANK2,ADCY1,NLGN4X,PRKCQ,WNT11,SATB2,ATOH1,AMIGO1,JAM3,FGFR1,IRS2,LAMB1,GRB10,MAPK10,COBL,CTNND2,CNTN1,TENM1,TNIK,FARP1,ROBO2,FZD8,LRP4,APBB1,KIF5C,EPHB1,GDPD5,NEDD4,NEO1,NKX6-1,LRRC55,IRX5,LRRN1,MAP1A,SCN1B,SGK1,FIG4,DYNC2H1,NPTXR,PDLIM7,RAPGEF2,RERE,MAP1B,CEBPB,ID3,DOCK7,FAT4,GNAO1,XBP1,BMP4,FOXA1,SNPH |
| 8.699e-12 | -25.47 | upper_aerodigestive_tract | COSMIC cancer mutations | upper_aerodigestive_tract | 13556 | 1430 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,POU3F3,DCC,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,ST6GALNAC3,SNAP25,ZBBX,ARRDC4,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,WDR17,CKAP2,GCAT,FZD8,ESRP1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,PHACTR3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,PNRC1,COL4A3,SPOCD1,ANK2,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,ERN1,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,LRP6,ADCY6,MED7,FAR2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,RPS13,HRASLS,INTU,CSN2,TDRD3,PRDM13,ACO1,RNF125,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,USP30,SLC35F1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,ENPP6,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,THBS4,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ISG20,ZNF711,IKZF3,CCNA1,ZNF704,BMPR1A,COBL,STON2,PURG,MID1,HACE1,MYO1D,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,DYNC2H1,ERRFI1,TBC1D9,SMAD6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,ZDHHC15,GPR137C,HOXA1,ZFP62,TERT,MCC,SVIL,TNFRSF17,LARP1,DDIT3,ACSL1,UGT8,PTPN21,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,SCART1,STXBP6,FBXO4,CHADL,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,EEF2,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,PIBF1,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,PRAME,PTPRU,PTPN6,MVD,C3orf52,AMIGO1,CD40,BCL11A,ZNF569,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,TSPAN15,ARL15,SSX1,TNFSF13B,COL4A5,IGF2BP2,OVOL2,FAM174B,SEL1L3,BMP6,SYDE2,RAB11FIP5,FSD1,KCNJ4,SCN1B,PRKCD,STC2,MARCH3,AFAP1L2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,SMAD9,GJB2,CAP2,TGFA,MSRB3,F12,CA13,ALDOA,ZBTB20,TMEFF2,MEF2C,CRYL1,LPP,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,GRPEL2,SYCP2,BNIP1,KIAA1671,FAM189A1,BACE2,ZIC5,LOXL4,ST8SIA1,NCAM1,TSPAN9,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,RAB38,TTC28,FGFR1,IRS2,IQCH,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,ALG11,TNFSF15,DBP,PLD5,KLHL31,SERINC5,FARP1,TMEM132C,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,P2RY1,PKN1,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,BCL7A,CLYBL,RAPGEF2,MCF2L2,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,LILRB1,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,CD55,GCNT2,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CBLN1,CYP26A1,FAM131B,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,THSD4,FGF12,RARRES2,FBXO36,PAGE5,FRK,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,KCNG1,ABI3,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,MKX,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,TTC39B,SIDT1,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,PACSIN1,TBC1D8,DCDC1,EML6,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,HLF,PLK2,ENTPD7,RASGRF2,CCBE1,SEMA3C,UNC5B,TANC2,LZTS1,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,DYNC1I1,CHD5,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,ZNF827,NELL2,STARD4,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,SOX21,PRKCQ,PNMA6A,TBC1D16,LINC00896,HTR7,ZNF396,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,ANKRD13D,MXI1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,GFI1,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,EXPH5,MPZL3,MVK,KIF5A,HEBP1,ANKRD18A,ABAT,RBM11,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,RTN1,CYP51A1,ARHGEF10L,LRRC6,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,NCAM2,NCOA7,APBA2,BCL11B,FN1,SEC24D,JDP2,RIMKLA,CYP4V2,LAMC3,ATP6V1E2,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,FAM107B,EBF4,NOS3,GPR176,ANKRD20A2,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,POU2F2,MET,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,RAB3B,NR4A1,CYTH3,GRID1,OGDHL,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SNPH |
| 1.050e-11 | -25.28 | neuron projection | cellular component | GO:0043005 | 1222 | 187 | 18223 | 1724 |
DOC2A,FGF13,GRIK2,PRSS12,KIF5A,ASS1,NDRG2,CADM2,ABAT,DNER,RAC3,NCS1,TUBB4A,BAG3,KCNAB1,KCNN2,LIN7A,CTTN,EPHB6,PACSIN1,MYRIP,DBN1,ATL1,GPM6A,KCNIP3,ATF4,DCC,WLS,ANK2,LRRK2,FEZ1,PRKAR2B,KCND3,ROR1,TRIM9,MAP2,NCAM2,PLK2,MAP9,TMOD2,INPP5F,NRP1,PPARGC1A,APBA2,MAGI2,LZTS1,BCL11B,PRKAA2,SV2B,GABRB2,SCN8A,OPHN1,SLC1A3,APBA1,PFN2,NAV1,CA2,CNTN4,IGF1R,PDZD7,FLRT3,OPN3,GRIP1,MPDZ,BNIP3,MORN4,STXBP1,ZNF385A,CHRM3,PAK1,DPYSL5,UNC5C,BDNF,KCNQ3,MYO10,HOMER2,SNAP25,OR11H4,SPATA7,BAIAP2,CPEB1,DAGLA,RIPOR2,RPL28,SH3GL2,WDR19,MPP2,PTPRN2,CDH2,SEMA3A,SHTN1,MME,EPHA3,PRKN,DNM3,C4A,ABHD13,NTRK3,CANX,KIF21B,PRR7,PPP1R9A,SEMA6A,CTNNA2,TIAM2,CCDC120,EPB41L3,GPRIN1,CHRNA5,UNC13B,MYO3B,ADGRL1,DAB2IP,SCN2A,KCNB2,GARS,FZD4,SHANK2,PREX1,CHRNA6,NLGN4X,VIM,AMIGO1,CD40,TTLL7,GABARAPL1,SNCA,CAMK2N1,HTR7,WFS1,ITGA2,PAM,RGS10,PTPRS,BMPR1A,SEPT5,MAPK10,CTTNBP2,STON2,COBL,CTNND2,PSPH,TENM1,MYO1D,NECAB2,FARP1,ROBO2,BMPR2,BACE1,APBB1,EPS8,LRP4,BLVRB,KIF5C,GABRG2,P2RY1,GABRR2,EPHB1,KCNC4,GDPD5,ARHGAP44,NEDD4,RGS17,MAP1A,SCN1B,TRIM3,NPTXR,SEPT3,ATP2B1,PTPN13,MPP1,RAPGEF2,SYBU,ARHGAP32,RACK1,PALLD,HOMER3,MAP1B,DOCK7,GNAO1,CTSV,DLG2,NPHP1,KIF1B,ATP2B4,SNPH,ATP1A3 |
| 1.240e-11 | -25.11 | oesophagus | COSMIC cancer mutations | oesophagus | 15441 | 1586 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,TMED9,PPP2R2B,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,SLC39A14,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,PRICKLE1,FERMT2,PALLD,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,COL4A5,IGF2BP2,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,PAX9,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,FAM27C,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,CA2,EBF4,FAM107B,NCEH1,MORN4,NOS3,GPR176,ANKRD20A2,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.425e-11 | -24.97 | GO_NEUROGENESIS | MSigDB lists | GO_NEUROGENESIS | 1346 | 207 | 17377 | 1707 |
UGT8,FGF13,KIF5A,MCOLN3,GATA3,ENAH,CHAC1,DNER,RAC3,STK24,NCS1,PLS3,SKI,RTN1,RND2,EOMES,RAP2A,CTTN,PACSIN1,TLR4,ETV1,SLIT2,NKX2-1,DBN1,ATL1,GPM6A,MARK1,DCC,LRRK2,YAP1,FEZ1,EML1,TSKU,GSN,GPRC5B,MAP2,PLK2,SEMA3C,INPP5F,DLX2,UNC5B,NRP1,MAGI2,NEUROG2,LZTS1,MEF2C,UST,BCL11B,EFNB2,SEMA6B,LRFN5,RUNX2,CELSR1,FN1,PTPRD,GABRB2,OPHN1,LAMC3,SLC1A3,PHGDH,SPINK5,CHD5,DDIT4,CHN1,EFEMP1,NUMBL,NAV1,CNTN4,SEMA4F,EEF2,FRY,PDZD7,BCHE,GATA2,FLRT3,PRKG1,LRP6,ADCY6,GRIP1,NCAM1,STXBP1,RIMS2,DPYSL5,PAK1,BDNF,DISC1,UNC5C,SLITRK2,VLDLR,DCHS1,EFNA3,SMARCD3,SLITRK5,PRDM1,SDK1,SNAP25,CLN5,CPEB1,BAIAP2,NEGR1,DAGLA,THBS4,CSF1,HEYL,MATN2,CLMN,CDH2,SEMA3A,NKX2-8,EPHA3,NBL1,DNM3,ID1,CELSR3,AKAP5,RBFOX2,PLXNA2,BCL6B,NTRK3,NRXN1,PPP1R9A,CBLN1,SEMA6A,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,BCL6,ZNF521,DAB2IP,MARCKS,ZNF488,NTNG1,SEMA6C,FZD1,SSH3,EVL,FZD4,PRDM13,ADCY1,PREX1,NLGN4X,SATB2,WNT11,PRKCQ,VIM,AMIGO1,ATOH1,JAM3,FGFR1,BCL11A,NRG3,PTK7,LAMB1,HGF,BMPR1A,LIFR,COBL,CTNND2,CNTN1,WASF3,TNIK,FARP1,ROBO2,BMPR2,FZD8,PLAG1,LRP4,APBB1,KIF5C,PRDM8,P2RY1,GAS6,EPHB1,GDPD5,BMP6,PPP2R3A,NEDD4,NEO1,NKX6-1,LRRC55,LRRN1,SCN1B,KIAA0319,TFAP2A,SGK1,DYNC2H1,FIG4,GFI1,SLC45A3,FES,VEGFC,RAPGEF2,MAP1B,DKK1,RERE,CEBPB,ID3,DOCK7,FAT4,GNAO1,XBP1,BMP4,SHOX2,FOXA1,SNPH |
| 1.447e-11 | -24.96 | SMID_BREAST_CANCER_BASAL_DN | MSigDB lists | SMID_BREAST_CANCER_BASAL_DN | 645 | 118 | 17377 | 1707 |
EPHA3,SIDT1,GALNT6,HEBP1,ATP8A1,UGDH,GATA3,FAM198B,ABAT,NOVA1,COL14A1,FAM110B,PCLO,SLC19A2,TBC1D30,CYP26A1,FAM131B,TBC1D19,CDS1,RTN1,NELL2,LRRC6,KCNAB1,KMO,SLC22A18,REEP1,RAB26,TMEM143,NBEA,ATRNL1,GSTM3,LIN7A,RAB27B,MYT1,CPE,HSPA2,PRKACB,DZANK1,SSH3,EVL,C3orf52,DEPTOR,ADCY1,EFHC1,KCND3,RAB38,BATF,ASPH,FGFR1,C9orf116,TSKU,CAMK2N1,ENPP1,ITGBL1,ATP7B,MAP9,INPP4B,MAOA,HPGD,SEMA3C,HGF,SERPINI1,TTC39A,PCSK5,TNIK,CELSR1,C1QTNF3,CLGN,ZCCHC24,BLVRB,BIK,DHCR24,CLSTN2,KIF5C,PSD3,COL4A5,SCD,ISYNA1,FAM174B,MTUS1,CHN2,IGF1R,RALGPS2,FRY,GATA2,FLRT3,MCF2L,STC2,SREBF1,TRIM3,TSPAN13,CERS4,MYO6,TBC1D9,MAST4,AGL,GFRA1,PCSK6,B9D1,VAV3,SLC27A2,ESRRG,CRIP2,SYBU,FASN,ARHGAP32,NPDC1,SPATA7,KCNK15,ICA1,THBS4,C1orf21,XBP1,PTPRN2,BMP4,FOXA1,ABCG1,SNPH |
| 1.529e-11 | -24.90 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | 402 | 84 | 17377 | 1707 |
FAM171B,PDE1B,AKAP5,SPATS2L,COLEC10,FAM13A,SLC19A2,DACH2,TIAM2,SIPA1L2,ASNS,KCNAB1,KAZN,ALDOC,ZNF521,NBEA,LIN7A,DAB2IP,TMEM132E,SLIT2,NTNG1,PDGFRB,DPP10,DZANK1,CD55,MARK1,DCC,TDRD3,PREX1,TCERG1L,AHRR,ENPP1,GYPC,KLF12,PRKCB,P4HA2,ZNF704,CTTNBP2,KCTD1,CNTN1,PCDH18,LRFN5,FARP1,TMEM132C,ROBO2,GABRB2,UBASH3B,STXBP6,RIMKLA,CREB5,SLC1A3,EPHB1,GAS1,IL17D,GAS2L3,FAM107B,SREBF1,CPXM2,SH3PXD2B,ATP2B1,KIAA1211,RNF152,CHSY3,PDLIM7,PCDH10,SYNPO2,RAB3B,ARID5B,PEX5L,SHISA2,LHPP,PALLD,GALNT14,NEGR1,CACHD1,PMEPA1,RND3,MATN2,LAPTM4B,CDH2,FNBP1L,MMP16,SMYD3,LARP1 |
| 1.582e-11 | -24.87 | PH-like_dom_sf | interpro domains | IPR011993 | 410 | 85 | 18492 | 1811 |
FRMPD3,ARHGAP26,DNM3,PLEKHA5,ARHGAP22,PTPN21,ENAH,TIAM2,NOS1AP,ARHGEF10L,EPB41L3,DAB2IP,RTKN2,GULP1,TLN2,GAB2,TBC1D8,PHLDB2,EVL,SKAP2,PREX1,TNS1,PLEKHA1,GRK3,ARHGEF26,PLEKHB1,IRS2,ARHGAP21,RANBP2,RASGRF2,PLEKHG1,GRB10,APBA2,FRMD5,FARP1,ARHGEF11,GRB14,TBC1D1,APBB1,EPS8,OPHN1,PSD3,APBA1,DOK5,PHLDA2,NUMBL,RALGPS2,MCF2L,AFAP1L2,CADPS2,IPCEF1,TBC1D9,EPB41L5,VAV3,ARAP2,SH3BP2,ARHGEF28,MYO10,TBC1D8B,PLEKHA8,PTPN13,MCF2L2,CYTH3,HOMER2,ASAP3,SPATA13,OBSCN,RASA3,FERMT2,AGAP2,CDC42BPA,SNTB1,SKAP1,TBC1D2,HOMER3,PLEKHH2,AKT3,OSBPL5,PLD1,SPRED3,IQSEC2,TBC1D4,OSBPL6,KIF1B,DOCK9 |
| 1.617e-11 | -24.85 | haematopoietic_and_lymphoid_tissue | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue | 14812 | 1535 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ERCC5,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,OBSCN,SDK1,KHDRBS2,GPR19,NEGR1,TBC1D2,GRIK4,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,USP30,SLC35F1,FOXP2,TTC1,TFAP2A,GTF2F2,TSC22D1,SGK1,KIAA0408,SYK,ATP2B1,DUSP1,LRRIQ1,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,SPEG,ASNS,ZNF438,POU5F1B,SHF,PDE4D,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,SH3BP2,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,JAKMIP3,SCN3A,DOCK8,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,P4HA1,RCN3,ALG11,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,UBASH3B,ZCCHC24,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,SLC22A17,ZDHHC6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,CHUK,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.621e-11 | -24.85 | neuron projection morphogenesis | biological process | GO:0048812 | 475 | 93 | 17256 | 1658 |
NBL1,UGT8,CELSR3,KIF5A,RBFOX2,PLXNA2,GATA3,ENAH,PRKCA,NRXN1,DDR1,RAC3,SEMA6A,STK24,CTNNA2,EPB41L3,COL25A1,DAB2IP,CTTN,PACSIN1,ETV1,ZNF365,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,ATL1,GPM6A,EVL,DCC,SHANK2,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,TSKU,IRS2,NCKAP1L,MAP2,GRB10,SEMA3C,NRP1,UNC5B,COBL,CTNND2,BCL11B,EFNB2,TNIK,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,EPHB1,FOXG1,DOK5,NEO1,CHN1,LRRC55,NUMBL,LRRN1,SEMA4F,MAP1A,CNTN4,SCN1B,FLRT3,SGK1,NCAM1,STXBP1,GFRA1,PAK1,PDLIM7,DPYSL5,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,RERE,MAP1B,DOCK7,SH3GL2,MATN2,NKX2-8,SEMA3A,SHTN1 |
| 1.959e-11 | -24.66 | HALLMARK_UV_RESPONSE_DN | MSigDB lists | HALLMARK_UV_RESPONSE_DN | 140 | 42 | 17377 | 1707 |
ID1,SCN8A,LDLR,PTPN21,TJP1,PRKCA,F3,EFEMP1,TGFBR3,IGF1R,SLC22A18,MYC,ITGB3,ACVR2A,MET,ATP2B1,SNAI2,PDGFRB,DUSP1,BDNF,CAP2,VLDLR,FHL2,PRKAR2B,CDC42BPA,MGMT,MAP1B,SMAD3,SLC7A1,DDAH1,ICA1,INSIG1,RND3,AKT3,INPP4B,SFMBT1,DBP,BMPR1A,NRP1,MAGI2,MMP16,ATP2B4 |
| 2.015e-11 | -24.63 | localization | biological process | GO:0051179 | 5343 | 634 | 17256 | 1658 |
DOC2A,THOC5,FLVCR2,GRIK2,PRSS12,DNAJC3,MCOLN3,NPM1,STAT5B,SNX9,PCDH7,SKI,TXNDC5,TGFBR3,PMAIP1,DNAH6,PPFIA2,RAP2A,RAB26,TMED9,TMEM37,COG3,CPE,POU3F3,NKX2-1,CFAP44,DCC,WLS,EXOC6B,TGFA,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,CA13,SLC7A1,ENPP1,WIPF3,ATP7B,ALDOA,BBC3,INPP5F,TMEFF2,MEF2C,SCN5A,TMEM63C,ITGA6,SLC36A4,GPSM2,BBS9,FOXG1,TTC30B,GRPEL2,BNIP1,CACNB2,FLRT3,PRELID2,LMAN2,CADPS2,LOXL4,DENND1C,JAM2,AGL,STXBP1,RPS23,LRP12,CHRM3,ZNF385A,SLC37A1,PNP,KCNQ3,MYO10,ARID5B,RYR2,HIP1,CALCRL,PLS1,SNAP25,ARRDC4,CLN5,SPATA7,CACHD1,TMCO3,SH3GL2,RPL28,CDH17,SELENOM,LAPTM4B,CDH2,TRPC3,SHTN1,DNM3,SCAMP1,TMSB15A,MYO1B,PKP2,ADD2,NRXN1,LCP2,SLC19A2,GPR15,EPB41L3,PLPP1,CHRNA5,RTKN2,FAM155B,ARL4D,SYNGR3,RAB27B,DNAH5,SNX10,SCN3A,DOCK8,KCNB2,FZD4,KCNH5,TRAM1L1,WNT11,RAB38,DSP,ASPH,FGFR1,GJC1,SLC39A14,CXCL10,ARHGAP21,GYPC,APELA,LAMB1,PAM,HOXB9,RAB30,SERINC5,IPO5,UBAC2,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,KCNC4,TSPAN17,BHLHA15,GHR,MYO6,FES,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,LCA5,RAB6B,RAPGEF2,RASA3,ATP11A,PTPRC,RPL12,OSBPL5,XBP1,SLCO5A1,HK1,BMP4,JHY,ATP2B4,TPT1,CACNG3,FGF13,SYT12,LILRB1,ITPR2,SYT14,NUP62CL,RND2,KCNAB1,KCNN2,SEC16B,ITGB3,TBC1D32,LIN7A,TLN2,TLR4,DBN1,ITGB7,CD55,KCNIP3,SLC3A2,MARK1,ABCC4,ANK2,ATOX1,PLEKHA1,SPNS1,TRIM9,KCNMB4,INSIG1,TNFRSF1A,PIK3C2B,TC2N,CHMP4C,RRAGD,PRKAA2,KCNV1,TYRO3,STXBP5L,LGALS3,HID1,MLC1,PGAP1,SPIRE1,SEMA4F,ABCA5,GATA2,FRAS1,LRP6,BNIP3,NIPAL2,SLCO4C1,CKAP4,PAK1,NDUFA4L2,FGFR4,MID2,SLC27A2,SPATA13,PPFIA4,STRADB,OBSCN,BAIAP2,TBC1D2,MAPKAPK2,KCNK15,GRIK4,MFSD2A,SLC2A6,PLD1,SEMA3A,TESC,SIX2,MME,SFN,PRKN,ID1,AKAP5,DOCK1,RBFOX2,NTRK3,SLC7A2,DENND3,PCLO,CBLN1,CTNNA2,SLC22A17,LHX6,ZDHHC6,BCL6,ZDHHC23,SCN2A,SNAI2,RPS13,TMEM67,TUBA1A,CSN2,LRRC8B,NOP53,ACO1,CHRNA6,RARRES2,FRK,JAM3,RANBP2,IFT81,NRG3,PTPRJ,GBP1,PTK7,KCNG1,ITGA2,HGF,SEPT5,SLC6A9,GRB14,PAK5,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,SLC35F1,MAP1A,KCNMB3,SGK1,SH3PXD2B,SYK,SLC45A3,ATP2B1,PCSK6,PRICKLE1,FERMT2,PALLD,ILDR2,HOMER3,DOCK7,FBN1,DLG2,RPL4,SLC22A15,SLC1A5,TBC1D4,KIF1B,CACNA2D1,ACVR1,SIDT1,ATP8A1,LDLR,VAMP8,GATA3,RAC3,NCS1,SLC9A7,TRPS1,SLC16A2,SLC22A18,NDUFB8,SERINC2,KCNS3,PACSIN1,PLTP,TBC1D8,GDAP1,ERGIC1,SLC9C1,KLHL3,ACVR1C,LRMP,DNAJC6,BNIP3L,EFHC1,TNS1,SLC25A28,ACVR2B,ZDHHC14,GPC6,SFXN1,NCKAP1L,MFSD4A,SEMA3C,NRP1,EFNB2,MRC2,INPPL1,CELSR1,TBC1D1,GABRB2,SCN8A,DHCR24,OPHN1,SLC25A27,SLC1A3,APBA1,DYNC1I1,RPL13A,MCOLN2,NAV1,SLC7A11,PDZD7,MYC,PRELID1,PRKG1,GRIP1,SLC16A9,FAM155A,RIMS2,BOD1,EPB41L5,RPL26,QSOX1,DISC1,PLEKHA8,SLC36A1,TBC1D8B,DCHS1,RAPGEF4,VLDLR,PACSIN3,TTC30A,TTYH2,PEX5L,NPC2,CDC42BPA,VPS37D,PKN3,CECR2,THBS4,WDR19,MATN2,DYNC2LI1,SMYD3,PLA2G4A,FRMPD3,EPHA3,NBL1,AMOTL1,TCTN2,RHOD,PLXNA2,MSR1,DDR1,TBC1D30,ZFYVE9,CCDC120,ALDOC,STARD4,NBEA,SCRN1,DAB2IP,PDE4D,ATP6AP1L,SFXN4,CYB5R2,PREX1,NLGN4X,PRKCQ,CBY1,SATB2,ATOH1,PYGO1,ATP1B1,TBC1D16,ATP10D,SNCA,PRKCB,ASIC1,STON2,MID1,THOC3,DENND5B,RPS20,ANO10,MYO1D,MXI1,CLBA1,ATP9A,EPS8,ARL2,KIF5C,GABRR2,NDFIP2,SELENOP,NEDD4,LRRC55,SOAT2,GPR155,SGK3,PRKG2,SLC6A15,DYNC2H1,TBC1D9,SEPT3,SPRY2,TMC7,VAV3,SLC40A1,ARAP2,PXN,CACNA1E,RPL21,ZDHHC15,SKAP1,GPLD1,FGR,TERT,MCC,GRIN2D,DDIT3,ATP1A3,SLC43A1,EXPH5,UGT8,ACSL1,KIF5A,JCHAIN,SLC2A13,CACNB4,DNER,SLCO3A1,EPCAM,ADPRHL1,TUBB4A,LRRC6,AKAP7,SLC10A7,CNNM2,TRPC1,SLC2A12,CTTN,MYRIP,IL1RAP,SLIT2,RASGRP1,PDGFRB,CYP1B1,TNK2,GPM6A,SESN2,JPH1,COTL1,SGK2,GRK3,GSN,HPSE,OXTR,MAGI2,APBA2,SLC9B1,PCSK5,BCL11B,SV2B,FN1,BVES,SCART1,SEC24D,STXBP6,ATP6V1E2,DDIT4,EEF2,CA2,SLC30A4,RPS11,LRP3,SNX7,NOS3,ATP5IF1,HBG2,RHOQ,PODXL2,WWC1,SDC3,SLC46A3,STEAP1,HERPUD1,FCHO2,FAT1,SH3BP4,RAB31,HK2,PTPRN2,FNBP1L,OSBPL6,CREB3L2,CXCR5,CELSR3,PSTPIP2,CANX,PIBF1,DOCK2,CD53,SCIN,PDZD8,UNC13B,FABP6,REEP1,MAP7,STEAP3,PROS1,GULP1,POU2F2,HSPA2,DPP10,GCA,ANTXR2,FER,PHLDB2,PTPRU,SLC39A8,PTPN6,SYNJ2BP,CENPV,BACH2,KPNA3,DISP1,TNIK,TSPAN15,LRP4,CMTM8,TNFSF13B,IGF2BP2,OVOL2,RPL34,MCU,NKX6-1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,EHD3,KIAA0319,TRIM3,MARCH3,IPCEF1,TNFRSF11A,RIN2,RAB3B,MSX1,NR4A1,CYTH3,SYBU,GRID1,ASAP3,MEI1,PHACTR2,AGAP2,TLR6,PEAK1,LEPR,RERE,MAP1B,ICA1,MYADM,MFSD9,RND3,MPP7,NACC2,PRCP,SLC7A5,SLC18B1,RPS12,GEM,NPHP1,SLC16A10,ABCG1,SNPH,STOM |
| 2.261e-11 | -24.51 | STK33_NOMO_DN | MSigDB lists | STK33_NOMO_DN | 253 | 61 | 17377 | 1707 |
EXPH5,MTG1,GPT2,LGR4,ST14,RNF144A,LPCAT2,GALNT12,PSTPIP2,JDP2,CMTM8,BIK,SELL,FAM117B,SCD,TPD52L1,IL18R1,BEX2,NEDD4,NEO1,SYDE2,TXNRD3,IL17D,SLC35F1,ASNS,BACE2,KAZN,DSG2,CHRDL1,TMEM143,ZDHHC23,SAMD13,PTPRCAP,RASGRP1,LAMP3,PNMA2,MICAL2,SLC40A1,ITGB7,GPM6A,HNF4G,GJB2,JPH1,LRRK2,CR2,PLS1,SATB2,ST6GALNAC3,SHISA2,MFSD6,SLC39A14,DDAH1,TEX15,MATN2,BDH2,KLF5,SEMA3C,HOXD13,MAGI2,PSPH,SLC43A1 |
| 2.327e-11 | -24.48 | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | 204 | 53 | 17377 | 1707 |
GXYLT2,ZNF395,RHOBTB1,SYT12,PKP2,SCD,MGAT5B,ZNF219,PCLO,MTUS1,QPRT,PLS3,EPB41L3,ZNF362,ABLIM1,IDI1,MSMO1,CNKSR3,DACT1,C1orf53,PRICKLE2,RTKN2,LOXL4,TMEM37,PPP2R2B,NPTXR,FIGN,SMAD6,PRR16,DUSP1,HMGCR,MN1,ATL1,TUBA1A,CAP2,MGST3,COL4A4,DSTN,ARID5B,TMEM200C,TNS1,FGFR1,EBF1,INSIG1,GSTO2,NACC2,ITGBL1,MATN2,SQLE,TUFT1,TPM1,DHCR7,OCLN |
| 2.596e-11 | -24.37 | regulation of nervous system development | biological process | GO:0051960 | 820 | 138 | 17256 | 1658 |
FGF13,LDLR,GATA3,RAC3,STK24,NCS1,SKI,RND2,TYMP,EOMES,RAP2A,CTTN,PACSIN1,SLIT2,IL1RAP,PRKACB,DBN1,DCC,LRRK2,YAP1,FEZ1,GPRC5B,MAP2,PLK2,SEMA3C,SERPINI1,INPP5F,OXTR,DLX2,NRP1,SPART,MAGI2,MEF2C,BCL11B,EFNB2,UST,FN1,CELSR1,PTPRD,FOXG1,CHN1,NUMBL,CNTN4,SEMA4F,GATA2,FLRT3,GRIP1,ADCY6,GPR161,RIMS2,PAK1,DISC1,BDNF,SLITRK2,VLDLR,EFNA3,SMARCD3,SLITRK5,SNAP25,SDK1,BAIAP2,NEGR1,ADGRB3,HEYL,CSF1,CDH2,SEMA3A,SHTN1,EPHA3,NBL1,PRKN,DNM3,ZSWIM5,ID1,PLXNA2,HECW2,NTRK3,NRXN1,CBLN1,SEMA6A,PPP1R9A,ADGRL1,BCL6,DAB2IP,ZNF488,ZNF365,FZD1,GLI1,SSH3,FZD4,SHANK2,PREX1,VIM,ATOH1,AMIGO1,FGFR1,SNCA,NRG3,PTK7,PTPRS,HGF,BMPR1A,COBL,CNTN1,WASF3,TNIK,ROBO2,BMPR2,PLAG1,LRP4,APBB1,CLSTN2,EPHB1,GDPD5,BMP6,ARHGAP44,ADGRB2,NEDD4,NKX6-1,LRRN1,SCN1B,KIAA0319,FIG4,GFI1,SLC45A3,FES,VEGFC,LZTS3,RAPGEF2,DKK1,MAP1B,ID3,DOCK7,TERT,MYRF,BMP4,SHOX2,FOXA1 |
| 2.626e-11 | -24.36 | plasma membrane bounded cell projection morphogenesis | biological process | GO:0120039 | 479 | 93 | 17256 | 1658 |
NBL1,UGT8,CELSR3,KIF5A,RBFOX2,PLXNA2,GATA3,ENAH,PRKCA,NRXN1,DDR1,RAC3,SEMA6A,STK24,CTNNA2,EPB41L3,COL25A1,DAB2IP,CTTN,PACSIN1,ETV1,ZNF365,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,ATL1,GPM6A,EVL,DCC,SHANK2,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,TSKU,IRS2,NCKAP1L,MAP2,GRB10,SEMA3C,NRP1,UNC5B,COBL,CTNND2,BCL11B,EFNB2,TNIK,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,EPHB1,FOXG1,DOK5,NEO1,CHN1,LRRC55,NUMBL,LRRN1,SEMA4F,MAP1A,CNTN4,SCN1B,FLRT3,SGK1,NCAM1,STXBP1,GFRA1,PAK1,PDLIM7,DPYSL5,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,RERE,MAP1B,DOCK7,SH3GL2,MATN2,NKX2-8,SEMA3A,SHTN1 |
| 2.709e-11 | -24.33 | cell development | biological process | GO:0048468 | 1556 | 227 | 17256 | 1658 |
EXPH5,ACVR1,UGT8,KIF5A,GATA3,HDGFL3,ENAH,CEBPA,PRKCA,DNER,RAC3,STK24,SKI,TGFBR3,MARVELD2,ITGB3,POF1B,GSTM3,CTTN,PACSIN1,ETV1,SLIT2,PDGFRB,NKX2-1,ATL1,ITGB7,GPM6A,DCC,ANK2,LRRK2,FEZ1,ROR1,ARHGEF26,TSKU,INHBC,GSN,NCAM2,NCKAP1L,MAP2,AHNAK2,SEMA3C,TMOD2,UNC5B,NRP1,TPM1,MAGI2,MEF2C,BCL11B,EFNB2,TYRO3,LRFN5,RUNX2,FN1,BVES,GABRB2,OPHN1,LAMC3,TJP1,SLC1A3,CHSY1,PHGDH,FOXG1,ADGRG6,CHD5,DOK5,MYORG,FHOD3,CHN1,NUMBL,CNTN4,SEMA4F,FRY,PDZD7,GATA2,FLRT3,PRKG1,GRIP1,NCAM1,STXBP1,GFRA1,LRP12,ZNF385A,EPB41L5,PAK1,DPYSL5,UNC5C,BDNF,SLITRK2,MSTN,VLDLR,ARID5B,FHL2,EFNA3,SLITRK5,OBSCN,PRDM1,TAF4B,CLN5,BAIAP2,ADGRB3,SH3GL2,RIPOR2,MFSD2A,HEYL,MATN2,INHBE,CLMN,NKX2-8,SEMA3A,SMYD3,SFN,SHTN1,EPHA3,TFCP2L1,NBL1,ID1,CELSR3,IL15,ST14,RBFOX2,PLXNA2,COL18A1,NRXN1,RADIL,DDR1,PPP1R9A,SEMA6A,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,BCL6,DAB2IP,PDE4D,MET,POU2F2,SERPINH1,ZNF488,ZNF365,HSPA2,NTNG1,SNAI2,SEMA6C,GAB2,FER,EVL,MYLK3,FZD4,PTPN6,NKX3-2,SHANK2,ADCY1,PRKCQ,VIM,SATB2,PYGO1,ATOH1,AMIGO1,JAM3,FGFR1,GJC1,SMAD3,IRS2,LAMB1,SOHLH2,PTPRS,GRB10,KLF5,BMPR1A,ATG5,MAPK10,COBL,CTNND2,CNTN1,TENM1,TNIK,WASF3,FARP1,BMPR2,ROBO2,LRP4,APBB1,KIF5C,PRDM8,OVOL2,EPHB1,GDPD5,BMP6,NEDD4,COL27A1,NEO1,NKX6-1,LRRC55,IRX5,MAP1A,LRRN1,SCN1B,BHLHA15,SGK1,ACTA2,FIG4,NPTXR,PDLIM7,RAPGEF2,MEI1,FERMT2,FNDC3A,PALLD,PEAK1,RERE,MAP1B,HEG1,DKK1,PTPRC,DPY19L2,DOCK7,MYADM,FAT4,GNAO1,XBP1,MYOM2,MYRF,BMP4,LRRK1,SHOX2,FOXA1 |
| 3.200e-11 | -24.17 | PLASARI_TGFB1_TARGETS_10HR_DN | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_DN | 230 | 57 | 17377 | 1707 |
TRIM2,LGR4,PTPRD,LRRCC1,PRSS35,HERC6,EYA4,GAS1,PCDH7,TRPS1,FOXP2,TMEM53,ABLIM1,TGFBR3,CNKSR3,TMEM86A,MPPED2,ZNF521,PRICKLE2,TOX,GULP1,MARCKS,FMNL2,MED12L,CAND2,PARP9,CYP1B1,SLC40A1,UNC5C,MEIS2,GSTM2,ARID5B,TCEA3,BNIP3L,NFIA,PRKAR2B,SESN1,PLCB1,ZIC1,PLEKHH2,FAT4,RND3,MAP2,GBP1,WDR19,PLEKHG1,ARHGAP28,SVIL,DBP,SHOX2,SEMA3A,CDH2,LIFR,MLLT3,MMP16,RAB30,MEF2C |
| 3.332e-11 | -24.12 | cell projection morphogenesis | biological process | GO:0048858 | 481 | 93 | 17256 | 1658 |
NBL1,UGT8,CELSR3,KIF5A,RBFOX2,PLXNA2,GATA3,ENAH,PRKCA,NRXN1,DDR1,RAC3,SEMA6A,STK24,CTNNA2,EPB41L3,COL25A1,DAB2IP,CTTN,PACSIN1,ETV1,ZNF365,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,ATL1,GPM6A,EVL,DCC,SHANK2,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,TSKU,IRS2,NCKAP1L,MAP2,GRB10,SEMA3C,NRP1,UNC5B,COBL,CTNND2,BCL11B,EFNB2,TNIK,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,EPHB1,FOXG1,DOK5,NEO1,CHN1,LRRC55,NUMBL,LRRN1,SEMA4F,MAP1A,CNTN4,SCN1B,FLRT3,SGK1,NCAM1,STXBP1,GFRA1,PAK1,PDLIM7,DPYSL5,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,RERE,MAP1B,DOCK7,SH3GL2,MATN2,NKX2-8,SEMA3A,SHTN1 |
| 3.394e-11 | -24.11 | stomach-carcinoma-adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-adenocarcinoma | 15615 | 1598 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,KIAA0355,FAT1,SH3BP4,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,PACSIN1,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,ANKRD20A2,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,MARS,AGAP2,PHACTR2,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 3.843e-11 | -23.98 | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | MSigDB lists | BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP | 402 | 83 | 17377 | 1707 |
EPHA3,SORBS1,ID1,CFH,ATP8A1,COL18A1,NDRG2,FAM13A,NOVA1,COL14A1,SLC19A2,NELL2,TGFBR3,ASNS,RPS6KA2,TLR3,KCNAB1,PMAIP1,ABI3BP,CHRDL1,KCNS3,MET,RPL26L1,PLTP,CPE,CYP1B1,MARK1,ABCC4,LRRC8B,ANK2,ATF3,PRKAR2B,DSP,WARS,SLC7A1,GSN,CXCL10,HLF,POPDC3,MAOA,ZBTB20,OXTR,MOCOS,RGS16,FN1,C1QTNF3,PTPRD,RHOBTB1,REL,CBS,COL4A5,TPD52L1,SEL1L3,DOK5,MTUS1,SLC7A11,BCHE,MYC,STC2,EIF1,LIMCH1,KLF9,MOXD1,SPRY2,IGSF3,DUSP1,MICAL2,MYO10,SPATA6,FHL2,MAFB,MARS,DKK1,DDAH1,TRIB3,NACC2,MATN2,SLC7A5,RAI14,CLMN,GEM,CDH2,SLC43A1 |
| 3.850e-11 | -23.98 | oesophagus-carcinoma | COSMIC cancer mutations | oesophagus-carcinoma | 4367 | 540 | 17385 | 1698 |
DOC2A,GRIK2,DNAJC3,ALG1L,CTBP2,CADM2,DOCK3,CA8,EYA4,NOS1AP,TGFBR3,DNAH6,PPFIA2,FAAH2,PPP2R2B,KLHL29,SMAD9,DCC,WLS,DSTN,LRRK2,NFIA,ELMOD1,FEZ1,ABCC2,KCND3,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,ERCC5,INPP5F,ZBTB20,TMOD2,DNHD1,CRYL1,SCN5A,LATS2,STOX2,ITGA6,SLC36A4,BTBD9,CHN1,SYCP2,RSL24D1,FRY,KIAA1671,PAIP2B,SRGAP1,TOX,CADPS2,DENND1C,FIGN,GFRA1,MYO10,ARID5B,RYR2,PLS1,ST6GALNAC3,SHISA2,ZBBX,TAF4B,SPATA7,CACHD1,TEX15,SH3GL2,CDH17,INHBE,TRPC3,CDH2,DOCK9,DNM3,ZNF516,GALNT6,LRRCC1,ABHD13,LCP2,GPR15,TLR3,GPRIN1,CNKSR3,COL25A1,PJA1,DNAH5,MYT1,KCNB2,SCN3A,DOCK8,C3orf67,MYLK3,COL6A2,RNF145,KCNH5,ADCY1,RAB38,TTC28,DSP,ASPH,FGFR1,MAGI3,IRS2,ENTPD1,LAMB1,PLEKHG1,FAM149A,DBP,LRRC27,HOXB9,CCDC148,WDR17,C1QTNF3,ROBO2,ESRP1,PLAG1,C1orf226,SLC12A6,PKN1,ZNF219,COL27A1,NEO1,GAS2L3,GHR,C15orf41,MED12L,PARP9,MCF2L2,RASA3,ATP11A,NSD1,GNAO1,AKT3,SLCO5A1,PIP5KL1,DOCK6,FOXA1,PHC1,CCDC126,PHACTR3,MGAT5B,ITPR2,SYT14,FAM13A,FSTL5,PLS3,ANKRD42,RUFY4,RPS6KA2,SEC16B,KCNN2,KCNAB1,TMEM86A,ITGB3,COL19A1,TMEM132E,TLN2,TLR4,ETV1,NEB,MARK1,ABCC4,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,TCERG1L,TRIM9,KCNMB4,MAP2,GNB4,TECPR2,PIK3C2B,MLLT3,HS6ST3,RRAGD,CHMP4C,PRKAA2,STXBP5L,SETBP1,SORBS3,PFN2,FHOD3,ZBTB38,ABCA5,BCHE,ZNF440,GATA2,FRAS1,PDE10A,LRP6,FAR2,CKAP4,UNC5C,BTNL9,HOMER2,MGAT4B,SPATA13,WDR25,STRADB,OBSCN,MAFB,SDK1,BAIAP2,MAPKAPK2,PLD1,SEMA3A,MME,SIX2,CFH,DOCK1,RHPN2,ZNF83,NTRK3,LPIN3,SEZ6L2,KIF21B,DENND3,FAM110B,TNKS1BP1,PPP1R9A,PCLO,DDX60L,ZNF362,TACC2,EEPD1,ZDHHC23,BCL6,MYH15,CLVS2,SCN2A,TMEM56,EVL,THSD4,FGF12,CHRNA6,NRG3,GBP1,ITGA2,HGF,TTC39A,ZNF701,CTNND2,CNTN1,MAN2B2,TENM1,COL9A3,GRB14,APBB1,MCTP2,GABRG2,SELL,PPP2R3A,SLC35F1,TECPR1,MAP1A,PRICKLE2,KIAA0408,SLC45A3,ATP2B1,DLGAP1,MICAL2,LRRIQ1,NUAK2,PALLD,NPDC1,ILDR2,MKX,EBF1,FAT4,FBN1,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,SLC1A5,FILIP1,ACVR1,TCP11L2,LGR4,LDLR,VAMP8,DACH2,TRPS1,FAM168A,KCNS3,CHRDL1,ATRNL1,PACSIN1,MAGEA6,THSD1,TBC1D8,GLDC,GDAP1,DCDC1,KLHL4,TNS1,EFHC1,GPC6,NCKAP1L,ENPP6,ENTPD7,RASGRF2,CCBE1,DSEL,TANC2,NRP1,SPOCK3,KLF8,LRFN5,MRC2,FAM124A,ZHX3,PTPRD,ST6GAL1,OPHN1,GTF2IRD1,TNFRSF10C,WDFY4,ISYNA1,APBA1,ADSSL1,MECOM,GBGT1,NAV1,KIAA1257,SLC7A11,VWDE,PRKG1,RUNDC3B,CPXM2,MPDZ,FAM155A,COL9A2,RIMS2,PTCH2,EPB41L5,TBC1D8B,COL4A4,TTC30A,PEX5L,RABAC1,CDC42BPA,CCDC85A,PLCB1,XKR9,PLEKHH2,VPS37D,ISM1,PELI2,DYNC2LI1,MPP2,SFMBT1,SQLE,IQSEC2,SLFN5,AMPD1,EPHA3,ELOVL4,GPR65,CCDC110,OTX1,MSR1,CHUK,COL14A1,TIAM2,CCDC120,ZNF827,SPEG,ZNF438,NBEA,NAP1L3,PDE4D,B3GALT1,SOX21,PREX1,NLGN4X,PRKCQ,SATB2,DCBLD2,PRKCB,MAP3K21,CTTNBP2,HACE1,WASF3,ANKRD13D,ATP9A,PRSS35,GABRR2,RGS7,GDPD5,NEDD4,GPR155,AFF2,SGK3,FIG4,TBC1D9,SMAD6,VAV3,SLC40A1,ARAP2,CACNA1E,ZDHHC15,GUCY1A2,ZIC1,ZFP62,FGR,TERT,MYOM2,LARP1,KIF5A,ABAT,DNER,HMCN1,QPRT,RTN1,ABI3BP,DLX6,TRPC1,OR2W3,MYRIP,PTPRE,SLIT2,GPM6A,CAPN5,TMEM47,SGK2,EML1,TMEM132B,MAGI2,APBA2,GPR63,FN1,GALNT13,SCD,CD7,PCDHB14,FAM107B,EBF4,MORN4,LRP3,SNX7,PCDH10,SLITRK2,GSTM4,PARD3B,EDEM3,WWC1,LHPP,PRDM1,AMDHD1,PLAGL1,FCHO2,FAT1,SH3BP4,RAB31,PTPRN2,DISP2,FNBP1L,XKR4,DMXL2,EML5,SORBS1,NEK10,CELSR3,PSTPIP2,PLEKHA5,COBLL1,COL18A1,MORC4,HECW2,PIBF1,DOCK2,SP8,SCIN,COL22A1,KCTD15,UNC13B,PDZD8,CDC14B,REEP1,ZNF521,PROS1,GULP1,POU2F2,MET,DPP10,PRAME,MVD,AMIGO1,DOCK5,TTLL7,ZNF569,BCL11A,TPK1,ZNF93,KPNA3,RNF130,DISP1,LIFR,MAST1,OR51B5,TNIK,ENO2,PRSS16,CLGN,REL,ARL15,TNFSF13B,CLSTN2,NOTUM,DSG2,KIAA0319,AFAP1L2,IQGAP3,TNFRSF11A,USP2,RAB3B,CRIM1,HNF4G,ESRRG,NR4A1,GRID1,OGDHL,MEI1,AGAP2,ARHGAP32,GALNT14,LEPR,MAP1B,GPR37,ADAMTS17,ICA1,ACER2,UACA,KIF21A,RNF157,MMP16,STOM |
| 3.961e-11 | -23.95 | skin-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-head_neck-carcinoma-squamous_cell_carcinoma | 14603 | 1516 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,CLMN,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,DNAH5,ZNF365,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,ITGB3,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,USP30,SLC35F1,FOXP2,TTC1,TFAP2A,GTF2F2,TSC22D1,SGK1,KIAA0408,SYK,ATP2B1,CES3,LRRIQ1,FOXN3,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,LRMP,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,LRRC49,APBA1,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATOH1,PYGO1,ATP10D,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,RGS10,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,BTC,ZNF516,DNM3,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,RCN3,ALG11,TNFSF15,DBP,PLD5,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,PLPPR2,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,CD55,GCNT2,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,ZCCHC24,UBASH3B,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,TESC,MME,SFN,SIX2,AVPI1,CFH,LPCAT2,RBFOX2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,PAGE5,FRK,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,ATRNL1,BEND4,MAGEA6,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,NBEA,DAB2IP,NAP1L3,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,DENND5B,ANO10,WASF3,ANKRD13D,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,MPZL3,EXPH5,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,EBF4,FAM107B,MORN4,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,HSPA2,SUSD3,DPP10,PHLDB2,FER,SLC39A8,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,NACC2,PRCP,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 4.212e-11 | -23.89 | stomach | COSMIC cancer mutations | stomach | 16028 | 1629 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,ANKRD20A2,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 5.790e-11 | -23.57 | BENPORATH_EED_TARGETS | MSigDB lists | BENPORATH_EED_TARGETS | 1000 | 162 | 17377 | 1707 |
SIDT1,SYT12,MCOLN3,GATA3,NRN1,ANKRD18A,DACH2,EYA4,PPM1E,EOMES,KCNAB1,ZFYVE28,CNNM2,COL19A1,HRK,TMEM132E,SLIT2,RASGRP1,NKX2-1,CYP1B1,ACVR1C,DCC,WLS,TGFA,GJB2,FAM84A,ELMOD1,FEZ1,KCND3,TRIM9,HLF,CCBE1,ADRB1,TMOD2,DLX2,TMEFF2,MAGI2,NEUROG2,MLLT3,SPOCK3,HS6ST3,KCNV1,LRFN5,SV2B,RUNX2,LGALS3,BVES,GABRB2,STXBP6,RIMKLA,ZIC2,FAM81A,FOXG1,HPCAL4,EEF2,SLC30A4,GATA2,PDE10A,PRELID1,PRKG1,ST8SIA1,NCAM1,MOXD1,BARX1,COL9A2,GFRA1,CEBPD,RNF152,NDUFA4L2,RAX,ANKRD20A2,PCDH10,UNC5C,KCNQ3,SLC27A2,TCEA3,EFNA3,MAFB,PDE8A,SHISA2,PLCB1,BAIAP2,NXPH4,HOXD13,NKX2-8,SIX2,EML5,PCSK1N,PLXNA2,RGS20,OTX1,MAPK4,DENND3,CBLN1,CYP26A1,SCIN,COL25A1,LHX6,SCRN1,ZNF365,ANKRD18B,FZD1,IGFBP3,INTU,ANKRD20A3,TMEM65,PTPRU,NKX3-2,SOX21,PRDM13,ATF3,WNT11,ATOH1,DSP,BATF3,HTR7,ZNF711,CAMK2N1,MSC,IKZF3,BACH2,PRKCB,RGS10,HS3ST3B1,SUSD4,MID1,CTNND2,HEY1,FZD8,EPS8,CLSTN2,NKAIN2,COL4A5,EPHB1,KCNC4,BMP6,COL27A1,HOPX,NKX6-1,CHN2,AFF2,STC2,GHR,GFI1,TNFRSF11A,ULBP1,B4GALT6,MSX1,CACNA1E,GRID1,PRICKLE1,ILDR2,HOXA1,ZIC1,MKX,DKK1,EBF1,DPY19L2,DDAH1,SLCO5A1,PAX9,SHOX2 |
| 5.994e-11 | -23.54 | animal organ development | biological process | GO:0048513 | 2986 | 385 | 17256 | 1658 |
THOC5,ACVR1,PDE1B,LGR4,MCOLN3,GATA3,CEBPA,ADAMTS6,STAT5B,BCAN,AARS,RAC3,SKI,BAG3,TGFBR3,CHRDL1,CPE,POU3F3,NKX2-1,MEIS2,SMAD9,KLHL3,DCC,WLS,LRRK2,NFIA,MEF2B,FEZ1,AGO4,EFHC1,ACVR2B,SAV1,SFXN1,ENPP1,HLF,NCKAP1L,CCBE1,ATP7B,BMP1,SEMA3C,SPRY4,NRP1,TPM1,SPART,VASH2,MEF2C,SCN5A,GNG12,INPPL1,STOX2,CELSR1,GABRB2,MLF1,ITGA6,DHCR24,SLC25A27,OPHN1,HERC6,TNFRSF19,FOXG1,CHD5,MYORG,MECOM,SYCP2,ABLIM1,CNTN4,SLC7A11,PDZD7,FLRT3,MYC,SREBF1,PRKG1,TSPAN12,TOX,ZNF385A,IGSF3,PTCH2,EPB41L5,ENAM,COL4A4,VLDLR,ARID5B,DCHS1,FASN,FHL2,SMARCD3,CALCRL,RYR2,NSD2,PLCB1,CLN5,WDR19,CDH17,SELENOM,HOXD13,DHCR7,CDH2,TFCP2L1,ZNF516,ST14,OTX1,PLXNA2,PKP2,ADD2,DDR1,SPEG,TLR3,ASNS,DAB2IP,RTKN2,SERPINH1,SYNGR3,SNX10,ZNF365,PERP,GAB2,FZD1,MYLK3,FZD4,NKX3-2,SOX21,SHANK2,PREX1,ADCY1,NLGN4X,SATB2,WNT11,ATF3,CBY1,PYGO1,ATOH1,DSP,FGFR1,GJC1,IRS2,CXCL10,POPDC3,APELA,WFS1,LAMB1,WWTR1,PAM,HPGD,KLF5,DBP,BMPR1A,ATG5,HOXB9,CTTNBP2,STON2,COBL,MYO1D,ROBO2,FZD8,PLAG1,BIK,GAS6,PKN1,EPHB1,SELENOP,GDPD5,PHLDA2,COL27A1,KDM7A,HMGCS1,IRX5,AFF2,DYNC2H1,ERRFI1,YBX3,GFI1,SMAD6,SPRY2,ZFP36L2,VEGFC,B9D1,SLC40A1,RAPGEF2,AK4,HOXA1,GPLD1,ZIC1,HEG1,CEBPB,PTPRC,ID3,AKT3,GNAO1,XBP1,PCGF2,SVIL,TUFT1,GRIN2D,MYOM2,BMP4,LRRK1,JHY,SHOX2,FOXA1,ATP2B4,BTRC,EXPH5,FGF13,LILRB1,ASS1,NDRG2,ABAT,DNER,GSDME,PLS3,EPCAM,EOMES,KCNAB1,LRRC6,GRHL1,DLX6,TBC1D32,COL19A1,LIN7A,ETV1,NEB,SLIT2,PDGFRB,CYP1B1,GPM6A,COL4A3,ANK2,JPH1,NFE2L1,YAP1,CR2,PLEKHA1,ROR1,BATF,EML1,TSKU,DYRK1B,INSIG1,GNB4,DLX2,OXTR,PPARGC1A,MAGI2,PCSK5,BCL11B,TYRO3,RUNX2,BVES,LAMC3,ZIC2,CHSY1,PHGDH,SPINK5,SATB1,ADGRG6,IL18R1,PGAP1,FHOD3,DDIT4,EFEMP1,NUMBL,CA2,SEMA4F,ZNF354A,EEF2,GATA2,FRAS1,SMTN,LRP6,BNIP3,BARX1,NOS3,PAK1,RAX,ATP5IF1,UNC5C,MSTN,MAFB,SLITRK5,PRDM1,SDK1,BAIAP2,MAPKAPK2,RIPOR2,MFSD2A,CSF1,HEYL,HK2,SEMA3A,NKX2-8,SFN,SIX2,MME,CXCR5,CREB3L2,ID1,IL15,RBFOX2,COL18A1,NTRK3,DOCK2,CBLN1,SEMA6A,CTNNA2,RIDA,SETDB2,TACC2,KAZN,LHX6,BCL6,MYO3B,ACVR2A,MYH15,POU2F2,MET,SNAI2,GLI1,INTU,EVL,CSN2,PTPRU,TMEM65,PTPN6,FGF12,VIM,AMIGO1,RARRES2,JAM3,BATF3,SMAD3,ARMC4,MSC,NRG3,PTK7,RBPMS2,ITGA2,PTPRS,HGF,DISP1,HEY1,CNTN1,PCDH18,COL9A3,DYRK3,BMPR2,LRP4,OVOL2,BMP6,NKX6-1,FOXP2,DSG2,STC2,TFAP2A,ACTA2,SH3PXD2B,PCK2,TNFRSF11A,SYK,ATP2B1,PCSK6,MICAL2,MSX1,USP2,KDM5B,FOXN3,CRIP2,PRICKLE1,ZFPM2,PALLD,FNDC3A,LEPR,ILDR2,MGMT,DKK1,MKX,RERE,DOCK7,FAT4,EDA,FBN1,CTSV,PAX9,NPHP1,MMP16,SNPH |
| 6.764e-11 | -23.42 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | 994 | 161 | 17377 | 1707 |
UGT8,TRIM2,TCP11L2,DUSP8,RECK,ATP8A1,LSM11,C20orf194,TUBE1,CADM2,ITPR2,SLC2A13,PRKCA,DNER,IKZF2,PCDH7,TUBB4A,RND2,CPNE2,FBXO32,TGFBR3,SEC16B,IKZF5,RAP2A,PPP2R2B,VWA5A,KLHL29,PTPRE,TBC1D8,DBN1,ATL1,KCNIP3,MARK1,PNRC1,DCC,WLS,DEPTOR,BNIP3L,TNS1,PLEKHA1,SGK2,INTS6,ZDHHC14,AK1,TCF7L1,HLF,NCAM2,GNB4,BMP1,ARHGAP28,ZBTB20,SERPINI1,UNC5B,TMEFF2,APBA2,MLLT3,FRMD5,UST,TYRO3,LATS2,INPPL1,CYP2J2,UBASH3B,ELOVL7,OPHN1,LRRC49,SORBS3,SLC1A3,APBA1,PFN2,TTC30B,FHOD3,ABLIM1,NAV1,RALGPS2,BCHE,EBF4,BNIP3,ST8SIA1,NCEH1,JAM2,FMNL2,PAK1,TTYH2,PLS1,LHPP,NPC2,MBNL2,NEGR1,CSF1,MATN2,SH3BP4,MPP2,CLMN,DOCK9,SORBS1,DNM3,TCTN2,RNF144A,SPATS2L,DDR1,SPEG,CNKSR3,KAZN,REEP1,MARCKS,PDE4D,PROS1,ZNF365,KIAA1549,GATM,ANTXR2,PHLDB2,COL6A2,PDK1,SOX21,ATF3,PRKCQ,TBC1D16,JAM3,PLEKHG1,P4HA1,DBP,PURG,HEY1,SERINC5,MXI1,GRB14,BACE1,FZD8,LRP4,EPS8,GPR180,COL4A5,FAM174B,COL27A1,NEO1,FOXP2,CHN2,MAP1A,FUT9,CERS4,MYO6,PDLIM7,TMC7,KDM5B,AGPAT4,PRICKLE1,CCNG1,TGDS,MAP1B,GPR37,DOCK7,GNAO1,AKT3,PLXDC2,SVIL,KIF21A,KIF1B,BTRC,CACNA2D1 |
| 7.183e-11 | -23.36 | GO_MOVEMENT_OF_CELL_OR_SUBCELLULAR_COMPONENT | MSigDB lists | GO_MOVEMENT_OF_CELL_OR_SUBCELLULAR_COMPONENT | 1213 | 188 | 17377 | 1707 |
ACVR1,FGF13,KIF5A,GATA3,ENAH,STAT5B,DNER,SKI,TGFBR3,LRRC6,DNAH6,ITGB3,CTTN,PLTP,ETV1,SLIT2,NEB,RASGRP1,POU3F3,PDGFRB,NKX2-1,CYP1B1,TNK2,ITGB7,GPM6A,SLC3A2,MARK1,DCC,ANK2,LRRK2,FEZ1,TNS1,EFHC1,GPC6,NCKAP1L,WIPF3,SEMA3C,UNC5B,TMEFF2,NRP1,TPM1,DNHD1,MEF2C,TYRO3,BCL11B,EFNB2,SEMA6B,SCN5A,CELSR1,LGALS3,FN1,BVES,ITGA6,OPHN1,APBA1,DYNC1I1,TTC30B,DDIT4,CHN1,NAV1,CNTN4,SEMA4F,SLC7A11,GATA2,CACNB2,FLRT3,PRKG1,NCAM1,JAM2,NOS3,FGFR4,EPB41L5,DPYSL5,BDNF,DISC1,UNC5C,PODXL2,ARID5B,DCHS1,EFNA3,SPATA13,TTC30A,RYR2,SDC3,WWC1,CDC42BPA,SH3GL2,PKN3,FAT1,THBS4,MATN2,WDR19,PLD1,FNBP1L,CDH2,SEMA3A,SIX2,CXCR5,EPHA3,ID1,AMOTL1,CELSR3,DOCK1,RBFOX2,PSTPIP2,MYO1B,PLXNA2,PKP2,NTRK3,NRXN1,KIF21B,DDR1,SEMA6A,CTNNA2,GPR15,LHX6,DAB2IP,PROS1,PDE4D,DNAH5,SEMA6C,SNAI2,DOCK8,VNN2,FER,EVL,PTPN6,FGF12,PREX1,WNT11,PRKCQ,VIM,SATB2,ATP1B1,ATOH1,JAM3,FGFR1,CENPV,GJC1,ARMC4,IFT81,CXCL10,ARHGAP21,NRG3,PTK7,ITGA2,ABI3,LAMB1,HGF,HOXB9,ROBO2,ARHGEF11,GRB14,EPS8,SELL,KIF5C,OVOL2,P2RY1,GAS6,PKN1,EPHB1,NEO1,SCN1B,PRKCD,KIAA0319,DYNC2H1,MYO6,TNFRSF11A,SYK,PARP9,TRPM4,VEGFC,VAV3,NR4A1,RAPGEF2,ASAP3,PALLD,PEAK1,MAP1B,GPLD1,RERE,PTPRC,FGR,SLC7A5,KIF21A,KIF1B,CACNA2D1,ATP2B4 |
| 7.287e-11 | -23.34 | plasma membrane bounded cell projection | cellular component | GO:0120025 | 1984 | 271 | 18223 | 1724 |
DOC2A,GRIK2,PRSS12,ENAH,CADM2,SNX9,RAC3,NCS1,MOK,BAG3,DNAH6,GSTM3,PACSIN1,CFAP44,DCC,SLC9C1,WLS,LRRK2,FEZ1,PRKAR2B,EFHC1,ABCC2,KCND3,ARHGEF26,SH3RF1,PLK2,CCDC181,MAP9,TMOD2,INPP5F,SPRY4,TPM1,NRP1,DNHD1,LZTS1,INPPL1,GABRB2,ITGA6,SCN8A,OPHN1,SLC1A3,APBA1,BBS9,TTC30B,ABLIM1,NAV1,CNTN4,PDZD7,FLRT3,OPN3,GRIP1,MPDZ,STXBP1,CHRM3,GPR161,ZNF385A,EPB41L5,BDNF,DISC1,KCNQ3,MYO10,SPATA6,TTC30A,SNAP25,CDC42BPA,OR11H4,SPATA7,CPEB1,DAGLA,PLEKHH2,SH3GL2,RPL28,WDR19,MPP2,DYNC2LI1,CDH2,SHTN1,EPHA3,DNM3,AMOTL1,TCTN2,C4A,MYO1B,ABHD13,TBC1D30,TIAM2,CCDC120,EPB41L3,GPRIN1,CHRNA5,DAB2IP,DNAH5,KCNB2,DOCK8,GARS,FZD4,SHANK2,PREX1,NLGN4X,CBY1,GABARAPL1,SNCA,HTR7,SLC39A14,PEMT,WFS1,PAM,BMPR1A,ATG5,MAPK10,CTTNBP2,COBL,STON2,WASF3,MYO1D,FARP1,ROBO2,BACE1,EPS8,ARL2,KIF5C,PSD3,P2RY1,GABRR2,EPHB1,KCNC4,GDPD5,NEDD4,RGS17,DYNC2H1,MYO6,NPTXR,SEPT3,SPRY2,PDLIM7,B9D1,PXN,LCA5,PTPN13,MPP1,RAPGEF2,RACK1,FGR,GNAO1,MCC,SVIL,ATP2B4,FOXA1,ATP1A3,FGF13,KIF5A,NDRG2,ASS1,ABAT,DNER,TUBB4A,KCNN2,KCNAB1,LRRC6,ITGB3,TBC1D32,LIN7A,EPHB6,CTTN,TLN2,MYRIP,PRKACB,DBN1,ATL1,GPM6A,ATF4,KCNIP3,ANK2,PLEKHA1,ROR1,TRIM9,GSN,NCAM2,MAP2,OXTR,PPARGC1A,MAGI2,APBA2,SLC9B1,PRKAA2,BCL11B,SV2B,BVES,PFN2,IGF1R,CA2,ADCY6,BNIP3,MORN4,DPYSL5,PAK1,UNC5C,HOMER2,SPATA13,WWC1,CATSPERE,BAIAP2,RIPOR2,FAT1,PTPRN2,SEMA3A,TESC,MME,PRKN,NTRK3,KIF21B,CANX,PRR7,SEMA6A,PPP1R9A,CTNNA2,UNC13B,ADGRL1,MYO3B,SCN2A,GLI1,INTU,FER,TMEM67,EVL,CHRNA6,VIM,AMIGO1,CD40,TTLL7,ARMC4,CAMK2N1,IFT81,PTPRJ,ABI3,ITGA2,RGS10,PTPRS,SEPT5,CTNND2,PSPH,TENM1,NECAB2,BMPR2,LRP4,BLVRB,APBB1,GABRG2,ARHGAP44,MAP1A,SCN1B,EHD3,TRIM3,ACTA2,ATP2B1,CYTH3,SYBU,ASAP3,FERMT2,ARHGAP32,PALLD,MAP1B,HOMER3,DOCK7,MYADM,TMEM237,CTSV,DLG2,NPHP1,KIF1B,SNPH |
| 7.443e-11 | -23.32 | neuron projection development | biological process | GO:0031175 | 645 | 114 | 17256 | 1658 |
EPHA3,NBL1,UGT8,CELSR3,KIF5A,RBFOX2,PLXNA2,GATA3,HDGFL3,ENAH,PRKCA,NRXN1,DDR1,RAC3,PPP1R9A,SEMA6A,STK24,CTNNA2,EPB41L3,GPRIN1,COL25A1,DAB2IP,CTTN,PACSIN1,ETV1,ZNF365,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,ATL1,GPM6A,EVL,DCC,SHANK2,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,JAM3,TSKU,IRS2,NCAM2,NCKAP1L,MAP2,LAMB1,GRB10,SEMA3C,NRP1,UNC5B,COBL,CTNND2,CNTN1,BCL11B,EFNB2,TNIK,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,EPHB1,PHGDH,GDPD5,FOXG1,DOK5,NEDD4,NEO1,CHN1,LRRC55,NUMBL,CNTN4,FRY,LRRN1,SEMA4F,MAP1A,SCN1B,PDZD7,FLRT3,PRKG1,GRIP1,SGK1,NCAM1,NPTXR,STXBP1,GFRA1,LRP12,PDLIM7,PAK1,DPYSL5,BDNF,UNC5C,SLITRK2,RAPGEF2,VLDLR,EFNA3,SLITRK5,BAIAP2,RERE,MAP1B,DOCK7,SH3GL2,FAT4,GNAO1,MATN2,CLMN,NKX2-8,SEMA3A,SHTN1 |
| 7.934e-11 | -23.26 | bladder | COSMIC cancer mutations | bladder | 14512 | 1507 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,KIAA1217,BCAN,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,KLHL23,DCC,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,INPP5F,DIRAS1,TPM1,DNHD1,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,BBS9,FOXG1,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,TOX,CADPS2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,FHL2,FASN,HIP1,ST6GALNAC3,SNAP25,ZBBX,SPATA7,C11orf45,TEX15,CACHD1,RIMKLB,RPL28,QPCTL,CLMN,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,ALDH1L1,MAGEA3,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,BACE1,PLAG1,FZD8,CD276,ESRP1,BIK,UBAC2,PSD3,GAS6,SLC12A6,EPHB1,BEX2,HMGCS1,LRRN1,PCBP4,GHR,C15orf41,ZFP36L2,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,RASA3,AK4,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,MGAT5B,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,AADAT,SEC16B,CPVL,ITGB3,MPPED2,TMEM143,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,KCNIP3,ATF4,MARK1,COL4A3,PNRC1,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,FHOD3,SPIRE1,RNF180,GALNT1,NUMBL,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,LRP6,ADCY6,MED7,NIPAL2,FAR2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,EFNA3,GPSM1,SLITRK5,MAFB,STRADB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,KCNK15,GRIK4,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,DDX60L,SEMA6A,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,HRASLS,RPS13,INTU,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TSC22D1,TFAP2A,SGK1,TSPAN13,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,EXOG,PALLD,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,CD37,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,LGR4,LDLR,PRKCA,HECTD2,SLC9A7,TRPS1,TYMP,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ACVR1C,KLHL3,WISP3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,DSEL,MAPK13,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,SREBF1,PRKG1,GRIP1,CPXM2,PRR16,FAM155A,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,COL14A1,DDR1,TIAM2,ZFYVE9,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,SHANK2,PANK1,PREX1,NLGN4X,ATF3,SATB2,ATP1B1,PYGO1,ATOH1,ATP10D,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,MID1,COBL,PURG,STON2,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,KIF5C,HERC5,TPD52L1,INPP1,PHLDA2,RASSF8,LRRC55,IRX5,GPR155,AFF2,DYNC2H1,TBC1D9,ERRFI1,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,SH3BP2,PXN,ALDH2,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,TMEM126A,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,ACTL8,PTPN21,C20orf194,SLC2A13,HMCN1,LGI2,ADPRHL1,EPCAM,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,PPARGC1A,TNFSF4,MAGI2,FRMD5,PCSK5,GPT2,GPR63,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,SCD,CHSY1,SPINK5,PCDHB14,RNF141,EEF2,SLC30A4,ZNF354A,LIMCH1,RNF148,LRP3,CAND2,CEBPD,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,KIAA0355,CSAG1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,FNBP1L,NKX2-8,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,REEP1,C12orf60,ACVR2A,PROS1,TMEM120B,NTNG1,SP140L,SEMA6C,PRAME,PTPRU,PTPN6,C3orf52,AMIGO1,CD40,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,TRIM34,KPNA3,EIF4EBP1,TMPRSS9,RBPMS2,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,IGF2BP2,COL4A5,SEL1L3,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,FLVCR2,PRSS12,AASS,LSM11,DNAJC3,FAM102B,CADM2,STAT5B,CHAC1,DOCK3,NOS1AP,EYA4,PCDH7,EPDR1,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,PPFIA2,FAAH2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,TGFA,CAP2,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CARS,LATS2,GNG12,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,BNIP1,BACE2,CACNB2,ZIC5,LOXL4,ST8SIA1,NCAM1,ZNF518B,STXBP1,GLIS1,AGL,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,TAF4B,OR11H4,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,BTC,NUDT10,DNM3,ZNF516,TMSB15A,GALNT12,GALNT6,C4A,FAM131C,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,NRXN1,COLEC10,CDS1,GPR15,RNF150,EPB41L3,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,RAB27B,SYNGR3,JAKMIP3,ARL4D,PERP,SCN3A,DOCK8,DZANK1,SSH3,GARS,FZD4,KCNH5,NKX3-2,NPM3,RAB38,TTC28,FGFR1,METAP1D,IRS2,IQCH,GYPC,GPR160,WWTR1,PLEKHG1,INPP4B,PAM,RCN3,P4HA1,TNFSF15,PLD5,DBP,KLHL31,SERINC5,FARP1,ROBO2,EDA2R,C1QTNF3,IPO5,C1orf226,NKAIN2,P2RY1,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,GALNT3,PTPRC,TRIB3,ID3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,FOXA1,DCBLD1,TPT1,NBPF4,TRIM2,SYT12,FHDC1,LILRB1,ASS1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNAB1,EOMES,KCNN2,HPS1,MARVELD2,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,ABCC4,GDPD1,PLEKHA1,TCERG1L,BATF,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,RASL11B,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,SLC27A2,RNF170,HOMER2,TMTC4,TCEA3,SPATA13,PPFIA4,PDE8A,TEX9,LDHD,NAP1L5,MAPKAPK2,ATPAF2,CSF1,HEYL,MFSD2A,PANK3,TESC,SIX2,SFN,MME,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,ZNF83,RNF24,OR51B4,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CBLN1,CYP26A1,FAM131B,TBC1D19,SLC22A17,LHX6,ZDHHC6,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,TMEM67,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,SMAD3,RANBP2,NRG3,GBP1,PTK7,KCNG1,ITGA2,SEPT5,TTC39A,C8orf48,CNTN1,MAN2B2,COL9A3,PCDH18,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SELL,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,RASD2,EIF1,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,FMO4,ZNF214,ZNF808,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,CGN,MYCBP2,PPP4R4,ACVR1,PAGE1,LANCL3,TCP11L2,TTC39B,SIDT1,DUSP8,ATP8A1,PPFIBP2,GATA3,ADAMTS6,RAC3,DACH2,AARS,STK24,SLC16A2,SLC22A18,CFHR1,CHRDL1,ATRNL1,GSTM3,BEND4,PACSIN1,VWA5A,RCAN3,MAGEA6,PLTP,TBC1D8,DCDC1,EML6,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,TNS1,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,SFXN1,HLF,NCKAP1L,CCBE1,PLK2,RASGRF2,ENTPD7,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,ALOX5AP,EHHADH,CELSR1,ZHX3,PTPRD,GABRB2,SCN8A,OPHN1,SLC25A27,GTF2IRD1,WDFY4,ISYNA1,SLC1A3,TNFRSF10C,DYNC1I1,ADSSL1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,RUNDC3B,OPN3,TSPAN12,MPDZ,SAMD13,RIMS2,IGSF3,RNF152,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTC30A,TTYH2,CCDC85A,C4orf19,PLCB1,FAM162A,ZNF558,DAGLA,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,PLA2G4A,FRMPD3,EPHA3,TBKBP1,AMOTL1,PCSK1N,RASAL2,ELOVL4,RNF144A,GPR65,ZNF311,OTX1,KCTD12,CHUK,SPATS2L,NUDT12,TBC1D30,TMEM53,NELL2,ZNF827,STARD4,NBEA,SCRN1,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,HTR7,ZNF396,PRKCB,KLF5,GRB10,HS3ST3B1,ATG5,CTTNBP2,NR3C2,DENND5B,ANO10,WASF3,MXI1,ANKRD13D,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,SYNPO2,ARAP2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,PGM2L1,TUFT1,GRIN2D,MYOM2,B4GALT7,OCLN,ATP1A3,NUDT17,SLC43A1,EXPH5,MPZL3,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,CACNB4,RBM11,ABHD4,DNER,IKZF2,KREMEN1,FAM27C,CEP85L,QPRT,FKBP11,CYP51A1,ARHGEF10L,RTN1,LRRC6,GRHL1,AKAP7,DLX6,POF1B,SLC2A12,HRK,PCOLCE2,OR2W3,PTPRE,FANK1,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,BCL11B,UST,FN1,SEC24D,JDP2,RIMKLA,ELOVL7,CYP4V2,ATP6V1E2,LAMC3,GALNT13,CD7,SATB1,PHGDH,DDIT4,CA2,RPS11,FAM107B,NCEH1,BARX1,NOS3,ANKRD20A2,MSTN,SH2D2A,PARD3B,EDEM3,WWC1,DUSP9,PRDM1,LHPP,B4GALNT3,AMDHD1,GLCE,RAI14,HK2,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,MORC4,TDRKH,BCL6B,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,POU2F2,MET,ZNF460,HSPA2,SUSD3,DPP10,GCA,PHLDB2,FER,SLC39A8,TES,DOCK5,TTLL7,C1orf174,WARS,TPK1,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,CHN2,GTSF1,DSG2,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,GRID1,OGDHL,PRRG1,MEI1,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,C3orf70,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,NACC2,MPP7,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,STOM,SNPH |
| 7.934e-11 | -23.26 | urinary_tract | COSMIC cancer mutations | urinary_tract | 14512 | 1507 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,FASN,FHL2,HIP1,ST6GALNAC3,SNAP25,ZBBX,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,RPL28,QPCTL,CLMN,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,SLC12A6,GAS6,EPHB1,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,RPS13,HRASLS,INTU,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TFAP2A,TSC22D1,SGK1,TSPAN13,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,TPD52L1,INPP1,PHLDA2,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,SCD,CHSY1,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,PRAME,PTPRU,PTPN6,C3orf52,AMIGO1,CD40,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,COL4A5,IGF2BP2,SEL1L3,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,LPP,CARS,LATS2,GNG12,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,BNIP1,BACE2,CACNB2,ZIC5,LOXL4,ST8SIA1,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,CDS1,GPR15,EPB41L3,RNF150,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCH,GYPC,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,KLHL31,SERINC5,FARP1,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CBLN1,CYP26A1,FAM131B,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,KCNG1,SEPT5,TTC39A,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SELL,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ADAMTS6,DACH2,RAC3,AARS,STK24,CFHR1,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,RUNDC3B,OPN3,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,FAM27C,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,FAM107B,NCEH1,BARX1,NOS3,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,CHN2,GTSF1,DSG2,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SNPH,STOM |
| 8.053e-11 | -23.24 | GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 536 | 101 | 17377 | 1707 |
EPHA3,DNM3,ID1,FGF13,AKAP5,PLXNA2,GATA3,NTRK3,NRXN1,TBC1D30,SEMA6A,PPP1R9A,NCS1,STK24,TBC1D19,RND2,RAP2A,DAB2IP,MARCKS,CTTN,PACSIN1,SLIT2,SEMA6C,TBC1D8,DBN1,FER,SSH3,GPM6A,EVL,DCC,LRRK2,PREX1,FEZ1,PRKCQ,VIM,AMIGO1,TBC1D16,FGFR1,BCL11A,GPRC5B,PLK2,PTK7,ITGA2,KLF5,SEMA3C,INPP5F,HGF,ATG5,NRP1,MAGI2,LZTS1,COBL,CNTN1,MEF2C,UST,TNIK,SEMA6B,FN1,BMPR2,ROBO2,PTPRD,TBC1D1,LRP4,APBB1,PFN2,NEDD4,NKX6-1,CHN1,EFEMP1,NUMBL,SEMA4F,SCN1B,PRKCD,KIAA0319,ADCY6,SGK1,FIG4,GFI1,SPRY2,RIMS2,FES,DISC1,BDNF,RHOQ,MYO10,RAPGEF2,VLDLR,PLS1,SDK1,SNAP25,BAIAP2,CPEB1,MAP1B,TBC1D2,NEGR1,PLD1,BMP4,SEMA3A,CDH2,FNBP1L,SHOX2 |
| 8.168e-11 | -23.23 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-mantle_cell_lymphoma | 481 | 93 | 17385 | 1698 |
FAM171B,EPHA3,DMXL2,TFCP2L1,MVK,ATP8A1,NPM1,TDRKH,PRKCA,KIAA1217,KREMEN1,DOCK2,DACH2,HMCN1,FSTL5,TBC1D19,CDS1,PCDH7,PPFIA2,ANKFN1,COL19A1,ATRNL1,GULP1,TMEM37,FANK1,SLIT2,GLDC,GPM6A,MEIS2,EML6,DCC,ANK2,MEF2B,TTC22,ACVR2B,DOCK5,CRYBG3,GPC6,ARHGEF26,TMEM132B,NRG3,IQCH,PDLIM3,ITGBL1,NCAM2,WWTR1,ZNF704,SOHLH2,SEMA3C,PLD5,MAGI2,NR3C2,SPOCK3,FRMD5,CTNND2,CHMP4C,PCSK5,CCDC148,ROBO2,FZD8,FOXP2,KIAA1958,GALNT1,PRTFDC1,FRY,FAM189A1,PRELID2,PRKG1,PRICKLE2,SMAD6,STXBP1,FAM155A,LRP12,CHSY3,RAB3B,RAB6B,SPATA6,OGDHL,RASA3,SDK1,ZFPM2,PLCB1,MBNL2,NAALADL2,DAGLA,FAT4,PLOD2,ADAMTS3,L3MBTL4,PTPRN2,SH3BGRL2,CACNA2D1,ACSM3 |
| 8.915e-11 | -23.14 | DODD_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_UP | 1490 | 221 | 17377 | 1707 |
MPZL3,EXPH5,CGN,TTC39B,PTPN21,VAMP8,FHDC1,ASS1,NDRG2,ANKRD18A,ABAT,BCAN,DNER,ABHD6,STK24,EYA4,F3,MOK,RPS6KA2,LRRC6,AADAT,DNAH6,SLC22A18,ANKFN1,SERINC2,HRK,KIAA1614,RCAN3,VWA5A,FANK1,ATL1,CD55,MEIS2,ERGIC1,EML6,KLHL3,WLS,CAPN5,NFIA,CR2,TNS1,EFHC1,TTC22,ABCC2,MFSD6,FHAD1,AK1,GSN,HLF,TECPR2,CCDC146,AHNAK2,ADRB1,PIK3C2B,OXTR,TMEFF2,SPOCK3,CRYL1,MEF2C,PCSK5,UST,PRKAA2,GPT2,KLF8,ZNF395,LGALS3,JDP2,MLF1,DHCR24,YPEL2,BTBD9,ADSSL1,SPINK5,BBS9,TNFRSF19,NIPSNAP3B,OTUD1,ABLIM1,ZBTB38,KIAA1257,RALGPS2,BACE2,FLRT3,FAM107B,RUNDC3B,SLC16A9,LOXL4,FBXL2,NIPAL2,CAND2,QSOX1,CDH26,SLC37A1,SLC27A2,SPATA6,HOMER2,EFHC2,TCEA3,FHL2,WWC1,WDR25,PLS1,ZBBX,C4orf19,SLC46A3,CPEB1,SPATA7,BAIAP2,DHX32,MMP15,TMEM154,PKN3,LRRIQ3,PTPRN2,SFMBT1,CLMN,OSBPL6,SIX2,DOCK9,NBL1,BTC,ZSWIM5,NEK10,RASAL2,TCTN2,ST14,GALNT12,RHPN2,GRK6,SCIN,CDS1,TMEM53,UNC13B,TACC2,COL25A1,KAZN,ALDH1L1,REEP1,BCL6,SCRN1,NBEA,GULP1,MDH1B,DNAH5,GATM,CTH,C3orf67,DZANK1,TMEM67,TUBA1A,PTPRU,SHANK2,TCEAL3,CBY1,RAB38,AMIGO1,FBXO36,C4BPB,MAGI3,C9orf116,ZNF396,ARMC4,IQCH,GPR160,WFS1,CCNA1,KLF5,FAM149A,DBP,LRRC27,MBOAT2,COBL,HEY1,MYO1D,CCDC148,WDR17,BACE1,CMTM8,UBAC2,SLC12A6,GDPD5,SEL1L3,FAM174B,HOPX,MCU,MAP1A,MCF2L,EHD3,PRKCD,KIAA0319,RALGAPA2,MORN2,DYNC2H1,TBC1D9,DUSP1,B9D1,LCA5,PXN,USP2,RAPGEF2,FOXN3,SYBU,ASAP3,ARHGAP32,GALNT14,RERE,MKX,EBF1,MPP7,ZNF214,SRD5A3,KIAA0513,NEK11,ZNF474,SH3BGRL2,KIF21A,NPHP1,FILIP1,FOXA1,STOM,TPT1 |
| 9.072e-11 | -23.12 | cell projection | cellular component | GO:0042995 | 2051 | 278 | 18223 | 1724 |
DOC2A,GRIK2,PRSS12,ENAH,CADM2,SNX9,RAC3,NCS1,MOK,BAG3,DNAH6,GSTM3,PACSIN1,CFAP44,DCC,SLC9C1,WLS,LRRK2,FEZ1,PRKAR2B,EFHC1,ABCC2,KCND3,ARHGEF26,SH3RF1,PLK2,CCDC181,MAP9,TMOD2,INPP5F,SPRY4,TPM1,NRP1,DNHD1,LZTS1,INPPL1,GABRB2,ITGA6,SCN8A,OPHN1,TJP1,SLC1A3,APBA1,BBS9,TTC30B,ABLIM1,NAV1,CNTN4,PDZD7,FLRT3,OPN3,GRIP1,MPDZ,STXBP1,CHRM3,GPR161,ZNF385A,EPB41L5,BDNF,DISC1,KCNQ3,MYO10,SPATA6,TTC30A,SNAP25,CDC42BPA,OR11H4,SPATA7,CPEB1,DAGLA,PLEKHH2,SH3GL2,RPL28,WDR19,MPP2,DYNC2LI1,LAPTM4B,CDH2,SHTN1,EPHA3,DNM3,AMOTL1,TCTN2,C4A,MYO1B,ABHD13,TBC1D30,TIAM2,CCDC120,EPB41L3,GPRIN1,CHRNA5,DAB2IP,DNAH5,KCNB2,DOCK8,GARS,FZD4,SHANK2,PREX1,NLGN4X,CBY1,GABARAPL1,SNCA,HTR7,SLC39A14,WFS1,PEMT,PAM,BMPR1A,ATG5,MAPK10,CTTNBP2,COBL,STON2,WASF3,MYO1D,FARP1,ROBO2,BACE1,EPS8,ARL2,PSD3,KIF5C,P2RY1,GABRR2,EPHB1,KCNC4,GDPD5,NEDD4,RGS17,DYNC2H1,MYO6,NPTXR,SEPT3,SPRY2,PDLIM7,B9D1,PXN,LCA5,PTPN13,MPP1,RAPGEF2,RACK1,FGR,GNAO1,MCC,SVIL,PIP5KL1,ATP2B4,FOXA1,ATP1A3,FGF13,KIF5A,NDRG2,ASS1,ABAT,DNER,TUBB4A,KCNN2,KCNAB1,LRRC6,ITGB3,TBC1D32,LIN7A,EPHB6,CTTN,TLN2,MYRIP,PRKACB,DBN1,ATL1,GPM6A,ATF4,KCNIP3,ANK2,PLEKHA1,ROR1,TRIM9,GSN,NCAM2,MAP2,OXTR,PPARGC1A,MAGI2,APBA2,SLC9B1,PRKAA2,BCL11B,SV2B,BVES,PFN2,IGF1R,CA2,ADCY6,BNIP3,MORN4,DPYSL5,PAK1,UNC5C,RHOQ,HOMER2,SPATA13,WWC1,CATSPERE,BAIAP2,RIPOR2,FAT1,PTPRN2,SEMA3A,TESC,MME,PRKN,NTRK3,KIF21B,CANX,PRR7,SEMA6A,PPP1R9A,CTNNA2,SCIN,UNC13B,ADGRL1,MYO3B,SCN2A,GLI1,INTU,FER,TMEM67,EVL,CHRNA6,VIM,AMIGO1,CD40,TTLL7,ARMC4,CAMK2N1,IFT81,PTPRJ,ABI3,ITGA2,RGS10,PTPRS,SEPT5,CTNND2,PSPH,TENM1,NECAB2,KIZ,BMPR2,LRP4,BLVRB,APBB1,GABRG2,ARHGAP44,MAP1A,SCN1B,EHD3,ACTA2,TRIM3,SH3PXD2B,ATP2B1,CYTH3,SYBU,ASAP3,FERMT2,ARHGAP32,PALLD,MAP1B,HOMER3,DOCK7,MYADM,TMEM237,CTSV,DLG2,NPHP1,KIF1B,SNPH |
| 1.060e-10 | -22.97 | MOHANKUMAR_TLX1_TARGETS_DN | MSigDB lists | MOHANKUMAR_TLX1_TARGETS_DN | 164 | 45 | 17377 | 1707 |
TNIK,BTC,FGF13,CLGN,GALNT12,BIK,KIF5C,TUBE1,PSD3,LRRC49,FAM198B,SPINK5,RNF150,NELL2,ASNS,PPP1R26,CA2,SGK1,MARCKS,PROS1,FIGN,IGSF3,PTCH2,PHLDB2,RAB3B,SPATA6,WLS,C3orf52,FGF12,MAFB,KCND3,STEAP1,GPC6,EML1,MAP1B,EIF4EBP1,HPGD,MAPK13,SLC22A15,PLD1,UNC5B,HOXB9,PKIA,DDIT3,SLC43A1 |
| 1.080e-10 | -22.95 | other | COSMIC cancer mutations | other | 15297 | 1571 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,SLC19A2,TLR3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,SLC39A14,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,IGFBP3,RPS13,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,HEY1,TENM1,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,FMNL2,LRP12,CHRM3,RPS23,HMGCR,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,WWTR1,INPP4B,PLEKHG1,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,LPCAT2,XYLT1,OR51B4,ZNF83,LPIN3,SEZ6L2,CBLN1,PCLO,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,FAM27C,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,BARX1,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.192e-10 | -22.85 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | 79 | 29 | 17377 | 1707 |
PLA2G4A,DMXL2,MSX1,CRIM1,STAT4,PTPN13,SYBU,CALCRL,SHISA2,FAM198B,CA8,MECOM,GNAI1,TEX15,KMO,GAS2L3,INPP4B,HPGD,KLF5,TSPAN12,SEMA3C,LIMCH1,SERPINI1,TOX,PCOLCE2,DLX2,SCN2A,SLCO4C1,FIGN |
| 1.255e-10 | -22.80 | GNF2_MAPT | MSigDB lists | GNF2_MAPT | 40 | 20 | 17377 | 1707 |
SV2B,GPM6A,RAB6B,ANK2,KIF5C,PSD3,SLC1A3,RGS7,DOCK3,NRXN1,DYNC1I1,CAMK2N1,RTN1,SH3GL2,GNAO1,NAP1L3,NPTXR,STXBP1,KIF1B,PNMA2 |
| 1.306e-10 | -22.76 | TGGAAA_V$NFAT_Q4_01 | MSigDB lists | TGGAAA_V$NFAT_Q4_01 | 1751 | 251 | 17377 | 1707 |
PHACTR3,PPP4R4,FLVCR2,PDE1B,FGF13,PRSS12,VAMP8,MCOLN3,FHDC1,GATA3,NDRG2,CADM2,DOCK3,IKZF2,FSTL5,SLC9A7,HECTD2,TRPS1,ANKRD42,RND2,TYMP,LRRC6,EOMES,KCNN2,MARVELD2,PPFIA2,ATRNL1,SLC2A12,TMEM37,FANK1,ETV1,CPE,POU3F3,TBC1D8,DBN1,GDAP1,GCNT2,NR6A1,KLHL4,DSTN,ELMOD1,NFIA,YAP1,TNS1,COTL1,FGF17,KCND3,GPR150,SLC7A1,GSN,ENPP1,KLF12,RASGRF2,TNFRSF1A,SERPINI1,INPP5F,CAB39L,PPARGC1A,DNHD1,TPM1,MLLT3,MEF2C,PCSK5,HS6ST3,KLF8,MRC2,FN1,CHCHD7,JDP2,UBASH3B,SLK,MLF1,OPHN1,BTBD9,SORBS3,ZIC2,ISYNA1,GPSM2,FAM81A,APBA1,PHGDH,SPINK5,TNFRSF19,FOXG1,PFN2,IL18R1,MECOM,CHN1,CACNB2,FLRT3,ZIC5,FAM107B,LRP6,ST8SIA1,STXBP1,VGLL4,ZNF385A,RNF152,IGSF3,HMGCR,RAX,MID2,UNC5C,BDNF,PCDH10,SH2D2A,TBC1D8B,MGAT4B,PACSIN3,CALCRL,SLITRK5,AIG1,ST6GALNAC3,PRDM1,SNAP25,ARRDC4,PLCB1,MBNL2,KHDRBS2,NAP1L5,TEX15,KIAA0355,PELI2,C1orf21,TMEM117,SFMBT1,SEMA3A,MME,DOCK9,CXCR5,NEK10,AMOTL1,RASAL2,SCAMP1,RBFOX2,OTX1,MAPK4,TNKS1BP1,SEMA6A,ZNF827,TACC2,PPFIBP1,STARD4,ZNF521,BCL6,MAP7,PDE4D,SERPINH1,SCN2A,FAM155B,SCN3A,IGFBP3,DZANK1,TRDMT1,TUBA1A,SOX21,KCNH5,SHANK2,FGF12,ACO1,VIM,SATB2,RAB38,ATP1B1,TTLL7,ASPH,WARS,BCL11A,ZNF396,HTR7,SMAD3,IRS2,ZNF711,CXCL10,GYPC,PDLIM3,PTK7,ABI3,ITGA2,RCN3,KLF5,GRB10,HGF,HS3ST3B1,MAPK10,NR3C2,RAB30,CTNND2,MXI1,CCDC148,C1QTNF3,BMPR2,GCAT,KLHL13,PLAG1,NSUN6,NOTUM,CREB5,GDPD5,BMP6,NEDD4,ARHGAP44,PPP2R3A,COL27A1,MCU,NKX6-1,FOXP2,ATXN7L1,EIF1,SGK1,IPCEF1,IQGAP3,ERRFI1,GFI1,SPRY2,C15orf41,SMPDL3A,ATP2B1,RBMS2,PCSK6,VEGFC,RIN2,LCA5,USP2,HNF4G,ESRRG,NR4A1,AGPAT4,NUAK2,CTTNBP2NL,HOXA1,NAALADL2,RERE,MAP1B,ZIC1,ADAMTS17,EBF1,PLOD2,GNAO1,AKT3,XBP1,MCC,SVIL,DLG2,SH3BGRL2,KIF21A,BMP4,SHOX2,PTGES,ATP2B4,SLC43A1 |
| 1.471e-10 | -22.64 | large_intestine-rectum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-rectum-carcinoma-adenocarcinoma | 16326 | 1649 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,SLX1B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 1.497e-10 | -22.62 | regulation of localization | biological process | GO:0032879 | 2674 | 349 | 17256 | 1658 |
DOC2A,ACVR1,LGR4,RECK,ATP8A1,LDLR,VAMP8,GATA3,NHP2,PRKCA,ABHD6,NCS1,STK24,NOS1AP,BAG3,TGFBR3,PMAIP1,RAP2A,RAB26,KCNS3,TMEM37,PACSIN1,PLTP,NKX2-1,TBC1D8,ACVR1C,WLS,LRRK2,DNAJC6,BNIP3L,FEZ1,KCND3,GNAI1,ENPP1,NCKAP1L,CCBE1,PLK2,BBC3,SEMA3C,INPP5F,TPM1,NRP1,TMEFF2,SPOCK3,MEF2C,SCN5A,TBC1D1,ITGA6,SCN8A,SLK,OPHN1,SLC25A27,BTBD9,GPSM2,GAS1,MTUS1,CACNB2,PRELID1,SREBF1,SRGAP1,PRKG1,LMAN2,CADPS2,STXBP1,RIMS2,HMGCR,EPB41L5,BDNF,KCNQ3,TBC1D8B,RAPGEF4,PACSIN3,RYR2,NSD2,HIP1,PLS1,SNAP25,PLCB1,BEX4,SH3GL2,THBS4,TRPC3,CDH2,SHTN1,EPHA3,NBL1,BTC,DNM3,AMOTL1,RHOD,C4A,PLXNA2,MSR1,PKP2,CHUK,NRXN1,TBC1D30,KMO,CNKSR3,DAB2IP,MARCKS,PDE4D,RAB27B,SYNGR3,KCNB2,DOCK8,SCN3A,GAB2,GAPDH,PFKFB2,KCNH5,SHANK2,PREX1,WNT11,ATP1B1,DSP,TBC1D16,FGFR1,SNCA,IRS2,CXCL10,PRKCB,WFS1,APELA,ASIC1,LAMB1,PAM,GRB10,BMPR1A,ATG5,STON2,HACE1,C1QTNF3,IPO5,UBAC2,ARL2,NKAIN2,GAS6,P2RY1,PKN1,NDFIP2,KCNC4,PHLDA2,NEDD4,LRRC55,SGK3,PRKG2,MYO6,TBC1D9,SPRY2,FES,PARP9,TRPM4,B9D1,VEGFC,GSTM2,MPP1,CACNA1E,RAPGEF2,RASA3,RACK1,CTTNBP2NL,ZIC1,GPLD1,PTPRC,TRIB3,FGR,TERT,GNAO1,AKT3,XBP1,MCC,BMP4,DDIT3,ATP2B4,EXPH5,CACNG3,FGF13,TRIM16,SYT12,LILRB1,ITPR2,ABAT,SYT14,CACNB4,F3,RND2,ADPRHL1,KCNAB1,TCAF2,SEC16B,KCNN2,ITGB3,TRPC1,MYRIP,TLR4,IL1RAP,SLIT2,PDGFRB,RASGRP1,CYP1B1,TNK2,KCNIP3,ATF4,GCNT2,SESN2,ANK2,JPH1,SGK2,SERGEF,TRIM9,GSN,KCNMB4,INSIG1,MAP2,OXTR,PPARGC1A,TNFSF4,MAGI2,TC2N,FRMD5,PRKAA2,KCNV1,FN1,LGALS3,STXBP5L,BVES,RHOBTB1,UBASH3B,STXBP6,FBXO4,MLC1,PFN2,SLC30A4,SEMA4F,IGF1R,CA2,GATA2,NOS3,PAK1,ATP5IF1,UNC5C,RHOQ,HOMER2,SPATA13,WWC1,TBC1D2,KCNK15,RIPOR2,CSF1,HK2,SEMA3A,TESC,SFN,PRKN,SORBS1,ZSWIM5,AKAP5,DOCK1,CELSR3,HECW2,COL18A1,NTRK3,PCLO,PPP1R9A,SEMA6A,DOCK2,SCIN,UNC13B,REEP1,BCL6,MET,SCN2A,HSPA2,SNAI2,IGFBP3,ALG10B,DPP10,FER,PHLDB2,EVL,CSN2,PTPRU,PTPN6,FGF12,CHRNA6,GSTO1,SYNJ2BP,RARRES2,AMIGO1,CD40,DOCK5,JAM3,C4BPB,SMAD3,ARMC4,NRG3,PTPRJ,GBP1,KCNG1,ABI3,ITGA2,HGF,DISP1,SEPT5,CNTN1,TENM1,NECAB2,BMPR2,APBB1,LRP4,BMP6,MCU,NKX6-1,RAB11FIP5,KCNJ4,MAP1A,SCN1B,PRKCD,STC2,EHD3,DSG2,SGK1,TSPAN13,PCK2,RRAS2,TNFRSF11A,SYK,RAB3B,KDM5B,SYBU,TLR6,LRAT,HOMER3,MAP1B,DKK1,DOCK7,ICA1,MYADM,RND3,GCSAM,PRCP,MAP2K6,GEM,TBC1D4,PKIA,CACNA2D1,ABCG1,STOM |
| 1.760e-10 | -22.46 | rectum | COSMIC cancer mutations | rectum | 16329 | 1649 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,SLX1B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 1.765e-10 | -22.46 | GO_CELL_MOTILITY | MSigDB lists | GO_CELL_MOTILITY | 793 | 134 | 17377 | 1707 |
ACVR1,FGF13,GATA3,STAT5B,DNER,SKI,TGFBR3,LRRC6,DNAH6,ITGB3,CTTN,PLTP,SLIT2,POU3F3,PDGFRB,NKX2-1,CYP1B1,TNK2,ITGB7,GPM6A,SLC3A2,MARK1,DCC,LRRK2,TNS1,EFHC1,GPC6,NCKAP1L,SEMA3C,TMEFF2,NRP1,MEF2C,TYRO3,EFNB2,SEMA6B,CELSR1,LGALS3,FN1,BVES,ITGA6,OPHN1,DDIT4,NAV1,SEMA4F,SLC7A11,GATA2,FLRT3,PRKG1,JAM2,NOS3,FGFR4,EPB41L5,DISC1,PODXL2,ARID5B,DCHS1,SPATA13,SDC3,WWC1,CDC42BPA,PKN3,FAT1,THBS4,MATN2,PLD1,CDH2,SEMA3A,SIX2,EPHA3,ID1,AMOTL1,CELSR3,DOCK1,PSTPIP2,RBFOX2,PLXNA2,NTRK3,DDR1,SEMA6A,CTNNA2,GPR15,LHX6,DAB2IP,PDE4D,PROS1,DNAH5,SNAI2,DOCK8,SEMA6C,FER,PTPN6,PREX1,WNT11,PRKCQ,SATB2,ATP1B1,ATOH1,JAM3,CENPV,FGFR1,CXCL10,NRG3,PTK7,ITGA2,LAMB1,HGF,HOXB9,GRB14,EPS8,SELL,P2RY1,GAS6,OVOL2,EPHB1,PKN1,PRKCD,KIAA0319,TNFRSF11A,SYK,PARP9,TRPM4,VEGFC,VAV3,NR4A1,RAPGEF2,ASAP3,PALLD,PEAK1,RERE,GPLD1,PTPRC,FGR,SLC7A5,ATP2B4 |
| 1.765e-10 | -22.46 | GO_LOCALIZATION_OF_CELL | MSigDB lists | GO_LOCALIZATION_OF_CELL | 793 | 134 | 17377 | 1707 |
ACVR1,FGF13,GATA3,STAT5B,DNER,SKI,TGFBR3,LRRC6,DNAH6,ITGB3,CTTN,PLTP,SLIT2,POU3F3,PDGFRB,NKX2-1,CYP1B1,TNK2,ITGB7,GPM6A,SLC3A2,MARK1,DCC,LRRK2,TNS1,EFHC1,GPC6,NCKAP1L,SEMA3C,TMEFF2,NRP1,MEF2C,TYRO3,EFNB2,SEMA6B,CELSR1,LGALS3,FN1,BVES,ITGA6,OPHN1,DDIT4,NAV1,SEMA4F,SLC7A11,GATA2,FLRT3,PRKG1,JAM2,NOS3,FGFR4,EPB41L5,DISC1,PODXL2,ARID5B,DCHS1,SPATA13,SDC3,WWC1,CDC42BPA,PKN3,FAT1,THBS4,MATN2,PLD1,CDH2,SEMA3A,SIX2,EPHA3,ID1,AMOTL1,CELSR3,DOCK1,PSTPIP2,RBFOX2,PLXNA2,NTRK3,DDR1,SEMA6A,CTNNA2,GPR15,LHX6,DAB2IP,PDE4D,PROS1,DNAH5,SNAI2,DOCK8,SEMA6C,FER,PTPN6,PREX1,WNT11,PRKCQ,SATB2,ATP1B1,ATOH1,JAM3,CENPV,FGFR1,CXCL10,NRG3,PTK7,ITGA2,LAMB1,HGF,HOXB9,GRB14,EPS8,SELL,P2RY1,GAS6,OVOL2,EPHB1,PKN1,PRKCD,KIAA0319,TNFRSF11A,SYK,PARP9,TRPM4,VEGFC,VAV3,NR4A1,RAPGEF2,ASAP3,PALLD,PEAK1,RERE,GPLD1,PTPRC,FGR,SLC7A5,ATP2B4 |
| 1.880e-10 | -22.39 | large_intestine-caecum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-caecum-carcinoma-adenocarcinoma | 14652 | 1517 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,KCNMB3,TFAP2A,TSC22D1,SGK1,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,KCNS3,THSD1,GLDC,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATP1B1,ATOH1,PYGO1,ATP10D,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,ACVR2A,FHIT,PROS1,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,C3orf52,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,TMPRSS9,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,TNFSF13B,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,TGFBR3,DNAH6,FAAH2,PPFIA2,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,GJB2,CAP2,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,SLC36A4,TTC30B,GRPEL2,SYCP2,BNIP1,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,PLS1,OR11H4,TAF4B,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,DOCK8,SCN3A,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,FGFR1,IRS2,IQCH,GYPC,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,ALG11,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,BCL7A,LCA5,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,CD55,GCNT2,ABCC4,GDPD1,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,ZCCHC24,UBASH3B,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,MFSD2A,HEYL,PANK3,MME,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,PCLO,CBLN1,CYP26A1,TBC1D19,SLC22A17,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,KCNG1,ABI3,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,GRHL1,AKAP7,DLX6,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,ANKRD20A2,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 1.885e-10 | -22.39 | caecum | COSMIC cancer mutations | caecum | 14664 | 1518 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,KCNMB3,TFAP2A,TSC22D1,SGK1,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,KCNS3,THSD1,GLDC,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATP1B1,ATOH1,PYGO1,ATP10D,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,ACVR2A,FHIT,PROS1,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,C3orf52,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,TMPRSS9,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,TNFSF13B,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,TGFBR3,DNAH6,FAAH2,PPFIA2,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,GJB2,CAP2,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,SLC36A4,TTC30B,GRPEL2,SYCP2,BNIP1,KIAA1671,FAM189A1,BACE2,CACNB2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,DOCK8,SCN3A,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,FGFR1,IRS2,IQCH,GYPC,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,ALG11,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,BCL7A,LCA5,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,CD55,GCNT2,ABCC4,GDPD1,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,ZCCHC24,UBASH3B,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,MFSD2A,HEYL,PANK3,MME,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,PCLO,CBLN1,CYP26A1,TBC1D19,SLC22A17,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,KCNG1,ABI3,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,GRHL1,AKAP7,DLX6,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,ANKRD20A2,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 1.919e-10 | -22.37 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | 305 | 67 | 17377 | 1707 |
EPHA3,NBL1,IL13RA1,ABAT,SEZ6L2,KIAA1217,HMCN1,PPP1R9A,ZNF827,SIPA1L2,FKBP9,TGFBR3,JAKMIP2,GULP1,MARCKS,GAB2,NFIA,VIM,MFSD6,CRYBG3,GNAI1,GSN,KCNMB4,MAP2,DSEL,DLX2,DISP1,TANC2,MLLT3,MEF2C,MAN2B2,PCDH18,FN1,RHOBTB1,ZCCHC24,YPEL2,IGF2BP2,SATB1,MLC1,DOK5,TECPR1,SRGAP1,LIMCH1,TOX,VGLL4,SMAD6,FMNL2,ATP2B1,RIN2,CARD6,SLC40A1,QSOX1,IL17RD,FOXN3,ARID5B,SHISA2,NPC2,BAIAP2,DKK1,EBF1,DDAH1,FBN1,TUFT1,GEM,SLFN5,XKR4,NUDT17 |
| 1.969e-10 | -22.35 | SMID_BREAST_CANCER_BASAL_UP | MSigDB lists | SMID_BREAST_CANCER_BASAL_UP | 611 | 110 | 17377 | 1707 |
PLA2G4A,TFCP2L1,PCSK1N,TRIM2,DNM3,UGT8,ELOVL4,GALNT12,ACTL8,MCOLN3,RGS20,NDRG2,ADD2,CHAC1,PRKCA,PPM1E,ASNS,MAGEA3,HRK,PCOLCE2,MET,SERPINH1,MAGEA6,ENO1,PERP,LAMP3,GLDC,HRASLS,PGBD5,DBN1,PRAME,PDK1,NR6A1,CYB5R2,PRDM13,DNAJC6,COTL1,NT5DC2,PLEKHB1,WARS,BCL11A,ISG20,GJC1,CXCL10,TCF7L1,HPSE,GPRC5B,MAP2,GBP1,PTK7,KCNG1,WWTR1,KLF5,VASH2,APBA2,MID1,RRAGD,COL9A3,MOCOS,PRSS16,IL32,CKAP2,ITGA6,STXBP6,CBS,IGF2BP2,GPSM2,PHGDH,DYNC1I1,MLC1,PFN2,DDIT4,FUT9,BACE2,MYC,DSG2,SLC6A15,TOX,ST8SIA1,NCAM1,RRAS2,BARX1,GPR161,CAND2,LRP12,CHRM3,NDUFA4L2,RAB6B,MYO10,VLDLR,DUSP9,ATP11A,SNTB1,GALNT14,GPR19,SMPDL3B,ZIC1,HOMER3,DKK1,GPR37,PLAGL1,PLOD2,RND3,FAT1,SLC2A6,SLC7A5,SHOX2,CDH2,SFN,CSRP2 |
| 2.536e-10 | -22.10 | HALLMARK_ESTROGEN_RESPONSE_EARLY | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_EARLY | 198 | 50 | 17377 | 1707 |
BCL11B,NBL1,FARP1,CELSR1,RHOD,SYT12,BLVRB,ABAT,SLC7A2,OVOL2,TPD52L1,TBC1D30,SLC19A2,ABLIM1,RPS6KA2,IGF1R,PMAIP1,KAZN,MYC,STC2,REEP1,OPN3,MPPED2,MAST4,GFRA1,RASGRP1,GAB2,SLC37A1,SLC27A2,THSD4,SYBU,DEPTOR,FASN,FHL2,ADCY1,WWC1,FRK,TSKU,KCNK15,PDLIM3,WFS1,XBP1,SLC7A5,RAB31,SVIL,INPP5F,TTC39A,DHCR7,PTGES,SFN |
| 2.989e-10 | -21.93 | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | 308 | 67 | 17377 | 1707 |
ACSL1,MORC4,GATA3,ASS1,PKP2,RNF24,PCDH7,QPRT,TRPS1,RTN1,PMAIP1,KMO,TACC2,STEAP3,SYNGR3,HRASLS,EVL,C3orf52,YAP1,PRKAR2B,RAB38,PLEKHB1,SMAD3,GPRC5B,EIF4EBP1,PAM,P4HA1,MAOA,INPP5F,TNFSF4,COL9A3,ENO2,MLF1,CYP2J2,DHCR24,CLSTN2,SCD,MTUS1,RNF141,HMGCS1,CHN2,IGF1R,MSMO1,MCF2L,GHR,OPN3,MARCH3,LIMCH1,BNIP3,FAR2,TBC1D9,GFRA1,SMPDL3A,PCSK6,QSOX1,PNP,MYO10,VLDLR,FASN,AK4,SMARCD3,UCHL3,GALNT3,KCNK15,MAP2K6,WDR19,DHCR7 |
| 3.025e-10 | -21.92 | urinary_tract-bladder-carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma | 14450 | 1499 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,FASN,FHL2,HIP1,ST6GALNAC3,SNAP25,ZBBX,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,RPL28,QPCTL,CLMN,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,SLC12A6,GAS6,EPHB1,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,RPS13,HRASLS,INTU,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TFAP2A,TSC22D1,SGK1,TSPAN13,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATOH1,PYGO1,ATP10D,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,TPD52L1,INPP1,PHLDA2,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,SCD,CHSY1,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,PRAME,PTPRU,PTPN6,C3orf52,AMIGO1,CD40,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,COL4A5,IGF2BP2,SEL1L3,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,LPP,CARS,LATS2,GNG12,SLC36A4,TTC30B,GRPEL2,SYCP2,BNIP1,BACE2,CACNB2,ZIC5,LOXL4,ST8SIA1,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,CDS1,GPR15,EPB41L3,RNF150,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCH,GYPC,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,KLHL31,SERINC5,FARP1,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,MAP2,P4HA2,GNB4,TECPR2,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CYP26A1,FAM131B,TBC1D19,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,FBXO36,PAGE5,FRK,JAM3,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,KCNG1,SEPT5,TTC39A,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SELL,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ADAMTS6,DACH2,RAC3,AARS,STK24,CFHR1,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,RUNDC3B,OPN3,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,FAM27C,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,CYP4V2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,FAM107B,NCEH1,BARX1,NOS3,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,CHN2,GTSF1,DSG2,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SNPH,STOM |
| 3.240e-10 | -21.85 | cell part morphogenesis | biological process | GO:0032990 | 501 | 93 | 17256 | 1658 |
NBL1,UGT8,CELSR3,KIF5A,RBFOX2,PLXNA2,GATA3,ENAH,PRKCA,NRXN1,DDR1,RAC3,SEMA6A,STK24,CTNNA2,EPB41L3,COL25A1,DAB2IP,CTTN,PACSIN1,ETV1,ZNF365,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,ATL1,GPM6A,EVL,DCC,SHANK2,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,TSKU,IRS2,NCKAP1L,MAP2,GRB10,SEMA3C,NRP1,UNC5B,COBL,CTNND2,BCL11B,EFNB2,TNIK,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,EPHB1,FOXG1,DOK5,NEO1,CHN1,LRRC55,NUMBL,LRRN1,SEMA4F,MAP1A,CNTN4,SCN1B,FLRT3,SGK1,NCAM1,STXBP1,GFRA1,PAK1,PDLIM7,DPYSL5,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,RERE,MAP1B,DOCK7,SH3GL2,MATN2,NKX2-8,SEMA3A,SHTN1 |
| 3.333e-10 | -21.82 | TAATTA_V$CHX10_01 | MSigDB lists | TAATTA_V$CHX10_01 | 746 | 127 | 17377 | 1707 |
ARHGAP26,CGN,NEK10,RBFOX2,GPR65,MYO1B,VAMP8,PTPN21,PLXNA2,ENAH,IL13RA1,STAT5B,CADM2,SEZ6L2,CANX,NOVA1,SP8,CHST10,ARHGEF10L,TUBB4A,GPR15,EPB41L3,PPM1E,NELL2,KCTD15,EOMES,IKZF5,GRHL1,PPFIBP1,LHX6,MPPED2,BCL6,SERINC2,HRK,MARCKS,PJA1,PPP2R2B,ZNF488,ETV1,MYT1,NKX2-1,DPP10,TMEM67,SESN2,KLHL4,KCNH5,MEF2B,MSRB3,HTR7,ENTPD1,BACH2,POPDC3,ITGBL1,LAMB1,BMP1,HPGD,ZBTB20,DLX2,UNC5B,NRP1,MID1,CTNND2,MEF2C,TYRO3,PCDH18,LRFN5,INPPL1,BMPR2,JDP2,TNFSF13B,CLSTN2,RASL11B,COL4A5,PRDM8,CREB5,FOXG1,TTC30B,ARHGAP44,NEO1,MTUS1,MECOM,NKX6-1,FOXP2,ATXN7L1,CA2,CNTN4,SLC7A11,BACE2,FLRT3,TFAP2A,OPN3,FIGN,SMAD6,C15orf41,MED12L,NDUFA4L2,RAX,BDNF,MSX1,MSTN,FOXN3,CYTH3,VLDLR,PACSIN3,SLITRK5,AIG1,PRDM1,CCNG1,NAALADL2,MAP1B,ZIC1,ADAMTS17,PMEPA1,KIAA0355,PELI2,GNAO1,SLCO5A1,TMEM117,SH3BGRL2,BMP4,RNF122,SEMA3A,SHOX2,SFN,FILIP1,OCLN,ATP2B4 |
| 3.352e-10 | -21.82 | MEISSNER_NPC_HCP_WITH_H3K4ME2 | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3K4ME2 | 469 | 90 | 17377 | 1707 |
DOC2A,SIDT1,GRIK2,GALNT12,FHDC1,GATA3,PKP2,COL18A1,IL13RA1,MGAT5B,KIAA1217,RADIL,RAC3,RTN1,LGI2,EPCAM,EPB41L3,KCTD15,GPRIN1,HPS1,COL25A1,ITGB3,ZDHHC23,MAP7,GULP1,PACSIN1,SYNGR3,PTPRE,RASGRP1,PERP,TMEM56,C3orf67,SMAD9,TES,DNAJC6,FGF12,TCERG1L,GPR150,BATF3,BCL11A,NRG3,POPDC3,CCNA1,ARHGAP28,TPM1,TTC39A,TC2N,C2orf88,COL9A3,ANKRD13D,NECAB2,ATP9A,RIMKLA,CBS,PRDM8,GAS6,DYNC1I1,CHD5,PRRG4,PIK3AP1,SCN1B,PRKG2,CPXM2,CCDC122,PRICKLE2,SLC16A9,BARX1,SMPDL3A,MN1,USP2,SLC37A1,SLC27A2,TCEA3,AIG1,PLS1,PDE8A,CEBPB,NSD1,GRIK4,PLAGL1,TERT,MFSD2A,SLC2A6,EMILIN2,TMEM117,SLCO5A1,GRIN2D,LRRK1,ATP1A3,TLL2 |
| 3.709e-10 | -21.72 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | 200 | 50 | 17377 | 1707 |
FAM171B,DMXL2,PCDH18,TNIK,PRSS12,SEC24D,RECK,LSM11,LMCD1,ASS1,GPR180,FAM198B,SLC1A3,DNER,TNFRSF19,SNX9,DOK5,EYA4,PPP2R3A,F3,CHN1,SPEG,RPS6KA2,STC2,PRICKLE2,BNIP3,MARCKS,PRR16,ZNF365,IGFBP3,QSOX1,MICAL2,MEIS2,SPOCD1,HIP1,AK4,PRDM1,DKK1,DCBLD2,MAP2,PLOD2,MFSD2A,MATN2,INPP4B,SVIL,SEMA3C,TANC2,NRP1,MME,PKIA |
| 3.757e-10 | -21.70 | lung-right_lower_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-right_lower_lobe-carcinoma-adenocarcinoma | 5829 | 685 | 17385 | 1698 |
GRIK2,AASS,MCOLN3,NPM1,STAT5B,KIAA1217,SNX9,CA8,EYA4,NOS1AP,TGFBR3,IKZF5,PPFIA2,FAAH2,RAP2A,PPP2R2B,COG3,TSHR,POU3F3,MEIS2,DCC,KLHL23,WLS,DSTN,LRRK2,FEZ1,PRKAR2B,KCND3,SLC7A1,ENPP1,ZNF266,WIPF3,ATP7B,ARHGAP28,ERCC5,TMOD2,TPM1,DNHD1,TMEFF2,CRYL1,SCN5A,TMEM63C,CYP2J2,SLC36A4,BTBD9,GPSM2,FOXG1,BBS9,CHN1,SYCP2,FRY,BACE2,FLRT3,ZIC5,SRGAP1,CADPS2,ALPK1,ST8SIA1,NCAM1,MOXD1,ZNF518B,AGL,GLIS1,GFRA1,LRP12,CHRM3,BDNF,MYO10,STAT4,FASN,RYR2,HIP1,SMARCD3,CALCRL,ZBBX,MBNL2,SPATA7,CACHD1,TEX15,GSTO2,SH3GL2,EMILIN2,CDH17,CLMN,HOXD13,TRPC3,MTG1,DNM3,ZNF516,FAM131C,GALNT6,MYO1B,LRRCC1,PKP2,LCP2,RNF150,EPB41L3,GPRIN1,COL25A1,DACT1,ALDH1L1,FAM155B,RAB27B,MYT1,KCNB2,SCN3A,MYLK3,COL6A2,NKX3-2,KCNH5,ADCY1,WNT11,DSP,METAP1D,GJC1,IQCH,PDLIM3,GPR160,LAMB1,INPP4B,PAM,PLEKHG1,DBP,LRRC27,RAB30,SERINC5,ANKRD13B,C1QTNF3,ROBO2,CKAP2,FZD8,CD276,ESRP1,BACE1,PLAG1,IPO5,CBS,PKN1,EPHB1,KCNC4,BEX2,COL27A1,NEO1,GAS2L3,GHR,NPTXR,PARP9,PDLIM7,MN1,RAB6B,MCF2L2,RAPGEF2,RASA3,ATP11A,HEG1,GALNT3,PTPRC,NSD1,PCDHB7,PLOD2,AKT3,OSBPL5,XBP1,SLCO5A1,NEK11,HK1,ATP2B4,DCBLD1,CRISPLD1,TLL2,PHACTR3,TRIM2,FGF13,ASS1,LILRB1,MGAT5B,ITPR2,FAM13A,NOVA1,FSTL5,EOMES,CPVL,KCNAB1,AADAT,MARVELD2,ITGB3,MPPED2,COL19A1,JAKMIP2,KIAA1614,TMEM132E,TLN2,ENO1,TLR4,ETV1,NEB,ZNF391,ITGB7,MARK1,ABCC4,COL4A3,SPOCD1,ANK2,CR2,BATF,TCERG1L,CRYBG3,NT5DC2,TSKU,INHBC,MAP2,P4HA2,CCDC146,AHNAK2,PIK3C2B,NEUROG2,MLLT3,TC2N,HS6ST3,PRKAA2,KCNV1,STXBP5L,ITPRIP,ZCCHC24,SETBP1,SORBS3,ZNF215,MLC1,IL18R1,PGAP1,DOK5,FHOD3,HSPA12B,NUMBL,GALNT1,SEMA4F,ABCA5,BCHE,GATA2,FRAS1,PDE10A,GAN,HS3ST5,SMTN,ADCY6,FAR2,CKAP4,FGFR4,CHSY3,MID2,UNC5C,HOMER2,MGAT4B,PPFIA4,OBSCN,SLITRK5,SDK1,KHDRBS2,GPR19,TBC1D2,GRIK4,MFSD2A,PLD1,SEMA3A,PANK3,CFH,DOCK1,LPCAT2,XYLT1,RHPN2,NTRK3,FAM198B,SEZ6L2,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,TBC1D19,FAM131B,TACC2,LHX6,MYO3B,ZDHHC23,MYH15,CLVS2,SCN2A,FAM78B,CTH,GLI1,INTU,TMEM67,EVL,CSN2,ACO1,FGF12,RANBP2,NRG3,PTPRJ,PTK7,ABI3,KCNG1,PTPRS,HGF,MBOAT2,CTNND2,CNTN1,COL9A3,PCDH18,DYRK3,LPAR2,NECAB2,BMPR2,KLHL13,RUSC2,APBB1,GABRG2,SELL,PRDM8,USP30,FOXP2,FUT9,PRICKLE2,SH3PXD2B,SYK,SLC45A3,KIAA1211,ATP2B1,CES3,DLGAP1,MICAL2,LRRIQ1,PALLD,ILDR2,FAT4,FBN1,L3MBTL4,ZNF214,DLG2,TBC1D4,KIF1B,CACNA2D1,ZNF235,FAM171B,MYCBP2,CGN,ACVR1,LDLR,GATA3,DACH2,SLC9A7,TRPS1,ZFYVE28,FAM168A,CFHR1,SERINC2,CHRDL1,ATRNL1,BEND4,MAGEA6,VWA5A,PLTP,GLDC,GDAP1,DCDC1,ACVR1C,KLHL3,FAM84A,KLHL4,LRMP,TNS1,EFHC1,ZDHHC14,SAV1,ARHGEF26,GPC6,GNAI1,NCKAP1L,ENTPD7,RASGRF2,CCBE1,SEMA3C,DSEL,SPRY4,UNC5B,TANC2,NRP1,LZTS1,EFNB2,LRFN5,INPPL1,CELSR1,PTPRD,ZHX3,TBC1D1,SCN8A,ST6GAL1,GABRB2,MRPL22,GTF2IRD1,SLC1A3,ADSSL1,DYNC1I1,MCOLN2,NAV1,RALGPS2,ADCK1,PRKG1,CPXM2,GRIP1,MPDZ,TSPAN12,PRR16,FAM155A,RIMS2,RNF152,IGSF3,EPB41L5,PTCH2,DISC1,TBC1D8B,SLC36A1,COL4A4,RAPGEF4,DCHS1,PACSIN3,KIAA1324L,PEX5L,CCDC85A,CDC42BPA,PLCB1,DAGLA,ISM1,PELI2,LRRIQ3,MATN2,MPP2,IQSEC2,SLFN5,SMYD3,AMPD1,EPHA3,PLA2G4A,TBKBP1,RASAL2,RNF144A,GPR65,ZNF311,OTX1,PLXNA2,COL14A1,DDR1,SPEG,ASNS,POU5F1B,SCRN1,NBEA,NAP1L3,GATM,GAB2,TRDMT1,VNN2,SHANK2,PANK1,PREX1,NLGN4X,PRKCQ,CBY1,SATB2,ATOH1,ATP10D,DCBLD2,ZNF711,HTR7,POPDC3,PRKCB,TDO2,ZNF704,BMPR1A,NR3C2,STON2,COBL,DENND5B,WASF3,ANKRD13D,GLIPR1L1,ARL2,GPR180,RGS7,GDPD5,INPP1,PHLDA2,NEDD4,RASSF8,IRX5,SOAT2,AFF2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SMPDL3A,B4GALT6,VAV3,ARAP2,SYNPO2,CACNA1E,MPP1,ZDHHC15,GUCY1A2,HOXA1,ZIC1,OR2T33,PLXDC2,TUFT1,MYOM2,NUDT17,EXPH5,ACSL1,UGT8,KIF5A,UGDH,ACTL8,PTPN21,C20orf194,ABAT,DNER,CACNB4,HMCN1,F3,RTN1,EPCAM,ADPRHL1,SIPA1L2,PPM1E,LRRC6,GRHL1,ABI3BP,DLX6,CTTN,PCOLCE2,PTPRE,MYRIP,OR2W3,SLIT2,IL1RAP,PRKACB,PDGFRB,GPM6A,CAPN5,JPH1,ROR1,TMEM47,TMEM132B,AK1,TMEM150B,GPRC5B,ITGBL1,OXTR,PPARGC1A,APBA2,MAGI2,PCSK5,UST,BCL11B,GPR63,MOCOS,ZNF395,FN1,YPEL2,LAMC3,SCD,GALNT13,CHSY1,SATB1,PCDHB14,CA2,RNF148,SNX7,CDH26,HBG2,PCDH10,IL17RD,PODXL2,SLITRK2,PARD3B,EDEM3,DUSP9,WWC1,SLC46A3,AMDHD1,STEAP1,KIAA0355,FCHO2,HK2,RAB31,SH3BP4,PTPRN2,NXPH4,DMXL2,NEK10,ZSWIM5,SORBS1,IL15,CELSR3,HECW2,MORC4,COL18A1,DOCK2,ZSCAN5A,COL22A1,PDZD8,UNC13B,RPS6KL1,PPFIBP1,ZNF521,STEAP3,PROS1,WWC2,POU2F2,MET,ALG10B,DPP10,FER,PHLDB2,PRAME,PTPRU,CD40,TTLL7,TPK1,BCL11A,ARMC4,CAMK2N1,MAGEA12,LMLN,TMPRSS9,RGS10,SOHLH2,DISP1,LIFR,OR51B5,ENO2,ARHGEF11,REL,LRP4,CLSTN2,COL4A5,BMP6,SYDE2,RAB11FIP5,NKX6-1,DSG2,EHD3,KIAA0319,IQGAP3,CARD6,RIN2,HNF4G,CRIM1,NR4A1,SYBU,GRID1,OGDHL,MEI1,AGAP2,ARHGAP32,ZFPM2,LEPR,MAP1B,DPY19L2,MYADM,RND3,ACER2,PRCP,THSD7B,UACA,KIF21A,RNF157,IL9R,NPHP1,MMP16 |
| 3.757e-10 | -21.70 | right_lower_lobe | COSMIC cancer mutations | right_lower_lobe | 5829 | 685 | 17385 | 1698 |
GRIK2,AASS,MCOLN3,NPM1,STAT5B,KIAA1217,SNX9,CA8,EYA4,NOS1AP,TGFBR3,IKZF5,PPFIA2,FAAH2,RAP2A,PPP2R2B,COG3,TSHR,POU3F3,MEIS2,DCC,KLHL23,WLS,DSTN,LRRK2,FEZ1,PRKAR2B,KCND3,SLC7A1,ENPP1,ZNF266,WIPF3,ATP7B,ARHGAP28,ERCC5,TMOD2,TPM1,DNHD1,TMEFF2,CRYL1,SCN5A,TMEM63C,CYP2J2,SLC36A4,BTBD9,GPSM2,FOXG1,BBS9,CHN1,SYCP2,FRY,BACE2,FLRT3,ZIC5,SRGAP1,CADPS2,ALPK1,ST8SIA1,NCAM1,MOXD1,ZNF518B,AGL,GLIS1,GFRA1,LRP12,CHRM3,BDNF,MYO10,STAT4,FASN,RYR2,HIP1,SMARCD3,CALCRL,ZBBX,MBNL2,SPATA7,CACHD1,TEX15,GSTO2,SH3GL2,EMILIN2,CDH17,CLMN,HOXD13,TRPC3,MTG1,DNM3,ZNF516,FAM131C,GALNT6,MYO1B,LRRCC1,PKP2,LCP2,RNF150,EPB41L3,GPRIN1,COL25A1,DACT1,ALDH1L1,FAM155B,RAB27B,MYT1,KCNB2,SCN3A,MYLK3,COL6A2,NKX3-2,KCNH5,ADCY1,WNT11,DSP,METAP1D,GJC1,IQCH,PDLIM3,GPR160,LAMB1,INPP4B,PAM,PLEKHG1,DBP,LRRC27,RAB30,SERINC5,ANKRD13B,C1QTNF3,ROBO2,CKAP2,FZD8,CD276,ESRP1,BACE1,PLAG1,IPO5,CBS,PKN1,EPHB1,KCNC4,BEX2,COL27A1,NEO1,GAS2L3,GHR,NPTXR,PARP9,PDLIM7,MN1,RAB6B,MCF2L2,RAPGEF2,RASA3,ATP11A,HEG1,GALNT3,PTPRC,NSD1,PCDHB7,PLOD2,AKT3,OSBPL5,XBP1,SLCO5A1,NEK11,HK1,ATP2B4,DCBLD1,CRISPLD1,TLL2,PHACTR3,TRIM2,FGF13,ASS1,LILRB1,MGAT5B,ITPR2,FAM13A,NOVA1,FSTL5,EOMES,CPVL,KCNAB1,AADAT,MARVELD2,ITGB3,MPPED2,COL19A1,JAKMIP2,KIAA1614,TMEM132E,TLN2,ENO1,TLR4,ETV1,NEB,ZNF391,ITGB7,MARK1,ABCC4,COL4A3,SPOCD1,ANK2,CR2,BATF,TCERG1L,CRYBG3,NT5DC2,TSKU,INHBC,MAP2,P4HA2,CCDC146,AHNAK2,PIK3C2B,NEUROG2,MLLT3,TC2N,HS6ST3,PRKAA2,KCNV1,STXBP5L,ITPRIP,ZCCHC24,SETBP1,SORBS3,ZNF215,MLC1,IL18R1,PGAP1,DOK5,FHOD3,HSPA12B,NUMBL,GALNT1,SEMA4F,ABCA5,BCHE,GATA2,FRAS1,PDE10A,GAN,HS3ST5,SMTN,ADCY6,FAR2,CKAP4,FGFR4,CHSY3,MID2,UNC5C,HOMER2,MGAT4B,PPFIA4,OBSCN,SLITRK5,SDK1,KHDRBS2,GPR19,TBC1D2,GRIK4,MFSD2A,PLD1,SEMA3A,PANK3,CFH,DOCK1,LPCAT2,XYLT1,RHPN2,NTRK3,FAM198B,SEZ6L2,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,TBC1D19,FAM131B,TACC2,LHX6,MYO3B,ZDHHC23,MYH15,CLVS2,SCN2A,FAM78B,CTH,GLI1,INTU,TMEM67,EVL,CSN2,ACO1,FGF12,RANBP2,NRG3,PTPRJ,PTK7,ABI3,KCNG1,PTPRS,HGF,MBOAT2,CTNND2,CNTN1,COL9A3,PCDH18,DYRK3,LPAR2,NECAB2,BMPR2,KLHL13,RUSC2,APBB1,GABRG2,SELL,PRDM8,USP30,FOXP2,FUT9,PRICKLE2,SH3PXD2B,SYK,SLC45A3,KIAA1211,ATP2B1,CES3,DLGAP1,MICAL2,LRRIQ1,PALLD,ILDR2,FAT4,FBN1,L3MBTL4,ZNF214,DLG2,TBC1D4,KIF1B,CACNA2D1,ZNF235,FAM171B,MYCBP2,CGN,ACVR1,LDLR,GATA3,DACH2,SLC9A7,TRPS1,ZFYVE28,FAM168A,CFHR1,SERINC2,CHRDL1,ATRNL1,BEND4,MAGEA6,VWA5A,PLTP,GLDC,GDAP1,DCDC1,ACVR1C,KLHL3,FAM84A,KLHL4,LRMP,TNS1,EFHC1,ZDHHC14,SAV1,ARHGEF26,GPC6,GNAI1,NCKAP1L,ENTPD7,RASGRF2,CCBE1,SEMA3C,DSEL,SPRY4,UNC5B,TANC2,NRP1,LZTS1,EFNB2,LRFN5,INPPL1,CELSR1,PTPRD,ZHX3,TBC1D1,SCN8A,ST6GAL1,GABRB2,MRPL22,GTF2IRD1,SLC1A3,ADSSL1,DYNC1I1,MCOLN2,NAV1,RALGPS2,ADCK1,PRKG1,CPXM2,GRIP1,MPDZ,TSPAN12,PRR16,FAM155A,RIMS2,RNF152,IGSF3,EPB41L5,PTCH2,DISC1,TBC1D8B,SLC36A1,COL4A4,RAPGEF4,DCHS1,PACSIN3,KIAA1324L,PEX5L,CCDC85A,CDC42BPA,PLCB1,DAGLA,ISM1,PELI2,LRRIQ3,MATN2,MPP2,IQSEC2,SLFN5,SMYD3,AMPD1,EPHA3,PLA2G4A,TBKBP1,RASAL2,RNF144A,GPR65,ZNF311,OTX1,PLXNA2,COL14A1,DDR1,SPEG,ASNS,POU5F1B,SCRN1,NBEA,NAP1L3,GATM,GAB2,TRDMT1,VNN2,SHANK2,PANK1,PREX1,NLGN4X,PRKCQ,CBY1,SATB2,ATOH1,ATP10D,DCBLD2,ZNF711,HTR7,POPDC3,PRKCB,TDO2,ZNF704,BMPR1A,NR3C2,STON2,COBL,DENND5B,WASF3,ANKRD13D,GLIPR1L1,ARL2,GPR180,RGS7,GDPD5,INPP1,PHLDA2,NEDD4,RASSF8,IRX5,SOAT2,AFF2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SMPDL3A,B4GALT6,VAV3,ARAP2,SYNPO2,CACNA1E,MPP1,ZDHHC15,GUCY1A2,HOXA1,ZIC1,OR2T33,PLXDC2,TUFT1,MYOM2,NUDT17,EXPH5,ACSL1,UGT8,KIF5A,UGDH,ACTL8,PTPN21,C20orf194,ABAT,DNER,CACNB4,HMCN1,F3,RTN1,EPCAM,ADPRHL1,SIPA1L2,PPM1E,LRRC6,GRHL1,ABI3BP,DLX6,CTTN,PCOLCE2,PTPRE,MYRIP,OR2W3,SLIT2,IL1RAP,PRKACB,PDGFRB,GPM6A,CAPN5,JPH1,ROR1,TMEM47,TMEM132B,AK1,TMEM150B,GPRC5B,ITGBL1,OXTR,PPARGC1A,APBA2,MAGI2,PCSK5,UST,BCL11B,GPR63,MOCOS,ZNF395,FN1,YPEL2,LAMC3,SCD,GALNT13,CHSY1,SATB1,PCDHB14,CA2,RNF148,SNX7,CDH26,HBG2,PCDH10,IL17RD,PODXL2,SLITRK2,PARD3B,EDEM3,DUSP9,WWC1,SLC46A3,AMDHD1,STEAP1,KIAA0355,FCHO2,HK2,RAB31,SH3BP4,PTPRN2,NXPH4,DMXL2,NEK10,ZSWIM5,SORBS1,IL15,CELSR3,HECW2,MORC4,COL18A1,DOCK2,ZSCAN5A,COL22A1,PDZD8,UNC13B,RPS6KL1,PPFIBP1,ZNF521,STEAP3,PROS1,WWC2,POU2F2,MET,ALG10B,DPP10,FER,PHLDB2,PRAME,PTPRU,CD40,TTLL7,TPK1,BCL11A,ARMC4,CAMK2N1,MAGEA12,LMLN,TMPRSS9,RGS10,SOHLH2,DISP1,LIFR,OR51B5,ENO2,ARHGEF11,REL,LRP4,CLSTN2,COL4A5,BMP6,SYDE2,RAB11FIP5,NKX6-1,DSG2,EHD3,KIAA0319,IQGAP3,CARD6,RIN2,HNF4G,CRIM1,NR4A1,SYBU,GRID1,OGDHL,MEI1,AGAP2,ARHGAP32,ZFPM2,LEPR,MAP1B,DPY19L2,MYADM,RND3,ACER2,PRCP,THSD7B,UACA,KIF21A,RNF157,IL9R,NPHP1,MMP16 |
| 3.849e-10 | -21.68 | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | MSigDB lists | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | 1539 | 224 | 17377 | 1707 |
EXPH5,FAM171B,MPZL3,TRIM16L,PPP4R4,TCP11L2,TTC39B,CNTNAP3,RECK,KIF5A,MCOLN3,GATA3,ASS1,ENAH,NRN1,ABHD4,IKZF2,EYA4,ANKRD42,CDR2L,FBXO32,TGFBR3,IKZF5,POF1B,VWA5A,FANK1,THSD1,CPE,GDAP1,ITGB7,COL4A3,PNRC1,EXOC6B,DNAJC6,NFIA,NFE2L1,BNIP3L,EFHC1,TMEM47,PLEKHA1,CA13,GNAI1,GSN,TMEM150B,ZNF266,HPSE,ITGBL1,MAP2,CCDC146,TIGD4,AHNAK2,BMP1,SERPINI1,TMOD2,TANC2,MLLT3,PCSK5,UST,BCL11B,MRC2,CELSR1,FN1,BVES,ST6GAL1,YPEL2,GTF2IRD1,SETBP1,SCD,ISYNA1,CHSY1,SLC1A3,ADSSL1,MLC1,PRRG4,MTUS1,CHN1,CA2,IGF1R,PAIP2B,SREBF1,GAN,GRIP1,ALPK1,MAST4,RIMS2,LRP12,RNF152,PAK1,BDNF,TBC1D8B,SLC27A2,GSTM4,STAT4,EFHC2,SMARCD3,MAFB,C1R,LHPP,RABAC1,TAF4B,PLCB1,BAIAP2,C11orf45,CACHD1,FCHO2,PMEPA1,PKN3,FAT1,CSF1,C1orf21,WDR19,HK2,CLMN,PLD1,TESC,MME,TFCP2L1,NEK10,TCTN2,RASAL2,CELSR3,RNF144A,PLXNA2,RGS20,LACC1,DDR1,UBTD2,ZNF362,TLR3,ZNF438,KAZN,BCL6,NBEA,NAP1L3,DAB2IP,STEAP3,PROS1,PDE4D,ARL4D,ZNF488,TMEM56,DOCK8,CTH,IGFBP3,PRAME,FER,PHLDB2,NECAB1,FBXO36,FRK,ZNF618,GABARAPL1,IFT81,LMLN,IGIP,DUSP19,PAM,MAOA,ALG11,MAPK10,STON2,MID1,ZNF701,RAB30,PLSCR4,CCDC148,TSPAN15,KLHL13,CKAP2,REL,BLVRB,MCTP2,PSD3,IGF2BP2,COL4A5,CREB5,OVOL2,SLC12A6,NDFIP2,ZNF219,INPP1,TPD52L1,HOPX,TFAP2A,ACTA2,PRKG2,DHRS12,KLF9,FIG4,TBC1D9,B4GALT6,PARP9,PFKFB4,MN1,CARD6,VAV3,USP2,KDM5B,PTPN13,FOXN3,NUAK2,PRRG1,PRICKLE1,GUCY1A2,NAALADL2,SMPDL3B,HEG1,GPR37,CEBPB,ID3,RPL12,FAT4,MPP7,PLXDC2,MAP2K6,OSBPL5,MCC,UACA,NEK11,DLG2,MYOM2,BMP4,NUDT17,STOM |
| 4.355e-10 | -21.55 | GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 393 | 79 | 17377 | 1707 |
EPHA3,DNM3,ID1,FGF13,AKAP5,PLXNA2,GATA3,NTRK3,SEMA6A,PPP1R9A,STK24,NCS1,RND2,RAP2A,DAB2IP,MARCKS,CTTN,PACSIN1,SLIT2,SEMA6C,DBN1,SSH3,DCC,LRRK2,PREX1,FEZ1,VIM,AMIGO1,FGFR1,BCL11A,GPRC5B,PTK7,PLK2,SEMA3C,HGF,INPP5F,NRP1,MAGI2,COBL,LZTS1,MEF2C,CNTN1,UST,TNIK,SEMA6B,BMPR2,ROBO2,FN1,PTPRD,LRP4,APBB1,NEDD4,NKX6-1,EFEMP1,CHN1,NUMBL,SEMA4F,SCN1B,KIAA0319,ADCY6,SGK1,FIG4,GFI1,RIMS2,FES,DISC1,BDNF,RAPGEF2,VLDLR,SNAP25,SDK1,BAIAP2,CPEB1,MAP1B,NEGR1,BMP4,SHOX2,SEMA3A,CDH2 |
| 4.646e-10 | -21.49 | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN | MSigDB lists | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN | 291 | 64 | 17377 | 1707 |
EPHA3,FAM171B,GPT2,CCDC126,GXYLT2,SORBS1,RECK,LMCD1,GATA3,CBS,NRN1,DNER,SATB1,BEX2,EYA4,GAS1,FHOD3,SCIN,FOXP2,SIPA1L2,CHN2,ASNS,FUT9,ABI3BP,BHLHA15,FLRT3,PCBP4,REEP1,CHRDL1,RAB26,SMTN,ACTA2,SLC16A9,AFAP1L2,EPHB6,TLN2,NCAM1,SMAD6,PDLIM7,SYNPO2,COL4A4,DEPTOR,NFIA,SMARCD3,C1R,PYCR1,BEX4,GSN,CACHD1,RIMKLB,HLF,PDLIM3,ISM1,RBPMS2,GNAO1,SLC7A5,HPGD,BMP4,TANC2,TPM1,KCTD1,PKIA,CACNA2D1,CRYL1 |
| 5.169e-10 | -21.38 | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN | 148 | 41 | 17377 | 1707 |
EML5,SIDT1,CHCHD7,AKAP5,ST6GAL1,SLC25A27,SELL,TDRKH,NTRK3,KBTBD11,HECTD2,TECPR1,TGFBR3,IGF1R,RALGPS2,MYC,LRP6,ACVR2A,FAM84B,ST8SIA1,AGL,RASGRP1,CARD6,EVL,CD55,PDK1,KDM5B,RAB6B,WLS,CYTH3,RAPGEF4,PRRG1,PLEKHA1,TTC28,RERE,BACH2,ZBTB20,RNF122,KIF1B,AMPD1,DIRC2 |
| 5.182e-10 | -21.38 | synapse | cellular component | GO:0045202 | 876 | 139 | 18223 | 1724 |
DOC2A,CACNG3,GRIK2,PRSS12,SYT12,VAMP8,ENAH,NRN1,CTBP2,CADM2,NCS1,KCNN2,PPFIA2,RAB26,LIN7A,CTTN,PACSIN1,TLN2,MYRIP,CPE,GPM6A,KCNIP3,CAP2,ANK2,LRRK2,DNAJC6,PRKAR2B,ROR1,TRIM9,MAP2,SPART,APBA2,MAGI2,LZTS1,MEF2C,SV2B,GABRB2,OPHN1,APBA1,PFN2,SEMA4F,FLRT3,LRP6,GRIP1,MPDZ,BNIP3,CADPS2,STXBP1,RIMS2,CHRM3,BDNF,DISC1,UNC5C,HOMER2,PPFIA4,HIP1,RABAC1,SDK1,SNAP25,BAIAP2,CPEB1,DAGLA,GRIK4,ADGRB3,SH3GL2,FCHO2,MPP2,PTPRN2,CDH2,MME,DMXL2,PRKN,DNM3,SCAMP1,C4A,ADD2,KCTD12,NRXN1,CANX,PRR7,PCLO,CBLN1,PPP1R9A,CTNNA2,EPB41L3,UNC13B,CHRNA5,DACT1,ADGRL1,SYNGR3,RAB27B,SHANK2,NLGN4X,CHRNA6,SNCA,CAMK2N1,ASIC1,ITGA2,RGS10,PTPRS,SEPT5,CTTNBP2,STON2,SLC6A9,FARP1,BMPR2,APBB1,EPS8,BLVRB,LRP4,PSD3,GABRG2,CLSTN2,COL4A5,GABRR2,P2RY1,KCNC4,NEDD4,ARHGAP44,RGS17,KCNJ4,MAP1A,SEPT3,ATP2B1,DLGAP1,SLC40A1,LZTS3,RAB3B,RAPGEF2,GRID1,ARHGAP32,SNTB1,MAP1B,HOMER3,ICA1,DLG2,GRIN2D,ATP1A3,SNPH |
| 5.279e-10 | -21.36 | - | gene3d domains | 2.30.29.30 | 410 | 85 | 8148 | 867 |
FRMPD3,ARHGAP26,DNM3,PLEKHA5,ARHGAP22,PTPN21,ENAH,TIAM2,NOS1AP,ARHGEF10L,EPB41L3,DAB2IP,RTKN2,GULP1,TLN2,GAB2,TBC1D8,PHLDB2,EVL,SKAP2,PREX1,TNS1,PLEKHA1,GRK3,ARHGEF26,PLEKHB1,IRS2,ARHGAP21,RANBP2,RASGRF2,PLEKHG1,GRB10,APBA2,FRMD5,FARP1,ARHGEF11,GRB14,TBC1D1,APBB1,EPS8,OPHN1,PSD3,APBA1,DOK5,PHLDA2,NUMBL,RALGPS2,MCF2L,AFAP1L2,CADPS2,IPCEF1,TBC1D9,EPB41L5,VAV3,ARAP2,SH3BP2,ARHGEF28,MYO10,TBC1D8B,PLEKHA8,PTPN13,MCF2L2,CYTH3,HOMER2,ASAP3,SPATA13,OBSCN,RASA3,FERMT2,AGAP2,CDC42BPA,SNTB1,SKAP1,TBC1D2,HOMER3,PLEKHH2,AKT3,OSBPL5,PLD1,SPRED3,IQSEC2,TBC1D4,OSBPL6,KIF1B,DOCK9 |
| 6.784e-10 | -21.11 | KRIGE_AMINO_ACID_DEPRIVATION | MSigDB lists | KRIGE_AMINO_ACID_DEPRIVATION | 28 | 16 | 17377 | 1707 |
CARS,SESN2,ASS1,CBS,MARS,ATF3,CHAC1,WARS,DDIT4,CEBPB,TRIB3,ASNS,SLC7A11,STC2,DDIT3,CTH |
| 7.005e-10 | -21.08 | MTOR_UP.N4.V1_UP | MSigDB lists | MTOR_UP.N4.V1_UP | 185 | 47 | 17377 | 1707 |
CARS,SLC6A9,SEC24D,GPR65,LDLR,ASS1,MRPL22,CHUK,CHAC1,KIF21B,PHGDH,ABHD6,DDIT4,FKBP11,ASNS,MAP1A,SLC7A11,MSMO1,BCHE,OPN3,SREBF1,BNIP3,PJA1,PCK2,ULBP1,DBN1,SLC3A2,VLDLR,PHACTR2,MARS,ATF3,PLS1,BATF,PLCB1,HERPUD1,PYCR1,CEBPB,SLC39A14,TRIB3,EIF4EBP1,SLC7A5,SLC1A5,DHCR7,PANK3,PSPH,DDIT3,SLC43A1 |
| 7.117e-10 | -21.06 | plasma membrane bounded cell projection organization | biological process | GO:0120036 | 1081 | 165 | 17256 | 1658 |
UGT8,KIF5A,GATA3,HDGFL3,ENAH,PRKCA,RAC3,STK24,TUBB4A,LRRC6,DNAH6,RAP2A,TBC1D32,CTTN,PACSIN1,ETV1,SLIT2,NKX2-1,ATL1,GPM6A,ABCC4,DCC,LRRK2,FEZ1,PRKAR2B,PLEKHA1,ARHGEF26,TSKU,GSN,MAP2,NCKAP1L,NCAM2,SEMA3C,TPM1,NRP1,DNHD1,UNC5B,BCL11B,EFNB2,LRFN5,INPPL1,ITGA6,OPHN1,PHGDH,FOXG1,BBS9,TTC30B,DOK5,CHN1,ABLIM1,NUMBL,CNTN4,FRY,SEMA4F,IGF1R,PDZD7,FLRT3,PRKG1,GRIP1,NCAM1,STXBP1,GFRA1,LRP12,PAK1,DPYSL5,UNC5C,BDNF,DISC1,SLITRK2,SPATA6,VLDLR,EFNA3,SPATA13,SLITRK5,TTC30A,BAIAP2,SH3GL2,WDR19,MATN2,DYNC2LI1,CLMN,FNBP1L,NKX2-8,SEMA3A,SHTN1,EPHA3,NBL1,DNM3,TCTN2,RHOD,CELSR3,RBFOX2,PLXNA2,NRXN1,DDR1,PIBF1,PPP1R9A,SEMA6A,CTNNA2,EPB41L3,GPRIN1,CDC14B,COL25A1,DAB2IP,SNX10,ZNF365,DNAH5,NTNG1,SEMA6C,GAB2,INTU,EVL,TMEM67,TUBA1A,SHANK2,ADCY1,PRKCQ,CBY1,ATOH1,AMIGO1,JAM3,ARMC4,IRS2,IFT81,LAMB1,WWTR1,GRB10,KLF5,SEPT5,COBL,CTNND2,CNTN1,WASF3,TNIK,FARP1,ROBO2,APBB1,LRP4,KIF5C,EPHB1,GDPD5,NEDD4,NEO1,LRRC55,LRRN1,MAP1A,SCN1B,EHD3,SGK1,DYNC2H1,NPTXR,SEPT3,PDLIM7,B9D1,VAV3,RAPGEF2,RERE,MAP1B,DOCK7,TMEM237,FAT4,GNAO1,JHY,NPHP1,ATP1A3 |
| 7.482e-10 | -21.01 | stomach-adenocarcinoma | COSMIC cancer mutations | stomach-adenocarcinoma | 4188 | 513 | 17385 | 1698 |
MYCBP2,CGN,PPP4R4,LGR4,FLVCR2,TCP11L2,PDE1B,TTC39B,SIDT1,GRIK2,AASS,CNTNAP3,ATP8A1,LDLR,NPM1,ENAH,PRKCA,KIAA1217,AARS,DACH2,EYA4,NCS1,HECTD2,PCDH7,TRPS1,EPDR1,BAG3,TGFBR3,DNAH6,CHRDL1,KCNS3,ATRNL1,PPP2R2B,VWA5A,TSHR,GLDC,MEIS2,ERGIC1,DCDC1,SMAD9,NR6A1,WLS,CAP2,LRRK2,LRMP,PRKAR2B,TNS1,ACVR2B,MFSD6,INTS6,GPC6,GNAI1,PYCR1,SFXN1,ENPP1,SH3RF1,ENPP6,NCKAP1L,PLK2,ATP7B,RASGRF2,ENTPD7,ARHGAP28,ERCC5,DIRAS1,DSEL,UNC5B,TMEFF2,SPOCK3,LZTS1,EFNB2,CARS,LRFN5,KLF8,MRC2,CELSR1,DHCR24,GTF2IRD1,TJP1,SLC36A4,LRRC49,ISYNA1,GPSM2,APBA1,FOXG1,ADSSL1,HPCAL4,MECOM,MTUS1,MCOLN2,SYCP2,ABLIM1,NAV1,FRY,CNTN4,PIK3AP1,CACNB2,RUNDC3B,SRGAP1,GRIP1,CPXM2,ALPK1,LOXL4,FIGN,AGL,STXBP1,LRP12,RIMS2,CHRM3,HMGCR,IGSF3,EPB41L5,QSOX1,PNP,KCNQ3,TBC1D8B,SLC36A1,COL4A4,STAT4,SPATA6,VLDLR,RAPGEF4,ZNF605,FASN,KIAA1324L,HIP1,PLS1,TAF4B,PLCB1,SPATA7,CACHD1,TEX15,TMCO3,PLEKHH2,VPS37D,SH3GL2,ADAMTS3,LRRIQ3,EMILIN2,DYNC2LI1,CLMN,SFMBT1,LAPTM4B,CDH2,SMYD3,AMPD1,EPHA3,TCTN2,RASAL2,GPR65,ZNF311,MYO1B,LRRCC1,MSR1,PLXNA2,RGS20,PKP2,CHUK,GRK6,COLEC10,DDR1,COL14A1,ZFYVE9,TIAM2,NELL2,EPB41L3,SPEG,KMO,CNKSR3,COL25A1,DACT1,ALDH1L1,FAM133A,RTKN2,SERPINH1,DNAH5,MYT1,GATM,KCNB2,SCN3A,DOCK8,TRDMT1,RNF145,PFKFB2,FZD4,SOX21,SHANK2,PANK1,TRAM1L1,PREX1,ATOH1,DSP,ATP10D,METAP1D,MAGI3,ZNF396,HTR7,IQCK,ARHGAP21,CCNA1,PAM,ALG11,BMPR1A,PLD5,HS3ST3B1,KLHL31,LRRC27,CTTNBP2,COBL,MID1,HACE1,PLSCR4,ANKRD13B,WDR17,ROBO2,CKAP2,GLIPR1L1,GCAT,FZD8,BACE1,IPO5,PRSS35,PSD3,HERC5,SLC12A6,CREB5,PKN1,KCNC4,BEX2,NEO1,SOAT2,LRRN1,AFF2,SGK3,MYO6,ERRFI1,MED12L,TRPM4,TMC7,ALDH2,ARAP2,RAB6B,RAPGEF2,ZDHHC15,CTTNBP2NL,UCHL3,ZIC1,PTPRC,NSD1,PLOD2,TERT,PLXDC2,GNAO1,AKT3,MCC,SVIL,TUFT1,MYOM2,BMP4,HK1,SHOX2,ATP2B4,DCBLD1,OCLN,TLL2,TPT1,ATP1A3,EXPH5,PHACTR3,CACNG3,FGF13,ACTL8,FHDC1,C20orf194,MGAT5B,ITPR2,NOVA1,DNER,KREMEN1,SLCO3A1,HMCN1,FSTL5,FKBP11,ANKRD42,LGI2,CYP51A1,SIPA1L2,FKBP9,TM9SF2,CPVL,LRRC6,AKAP7,ANKFN1,MPPED2,CNNM2,LIN7A,TMEM132E,TLN2,FANK1,TLR4,IL1RAP,SLIT2,PDGFRB,GCNT2,MARK1,SESN2,CD55,COL4A3,ANK2,JPH1,SESN1,SPNS1,TRIM9,TMEM132B,TCF7L1,INHBC,HPSE,ITGBL1,NCAM2,MAP2,TECPR2,CCDC146,NCOA7,PPARGC1A,GPT2,UST,PRKAA2,MOCOS,RUNX2,STXBP5L,ZCCHC24,FBXO4,RIMKLA,SETBP1,LAMC3,SORBS3,GALNT13,SPINK5,IL18R1,FHOD3,RNF180,NUMBL,GALNT1,PRTFDC1,CA2,IGF1R,SLC30A4,ABCA5,PDE10A,GAN,LRP6,ADCY6,BNIP3,LIMCH1,SLCO4C1,CAND2,PAK1,FGFR4,DPYSL5,CHSY3,CDH26,PCDH10,SLITRK2,PARD3B,GSTM4,MGAT4B,TMTC4,MAFB,SLITRK5,PDE8A,SDK1,SLC46A3,KHDRBS2,LDHD,NEGR1,GRIK4,KIAA0355,CSF1,MFSD2A,RAI14,TMEM117,PTPRN2,DISP2,SEMA3A,OSBPL6,MME,DMXL2,ZSWIM5,NEK10,CFH,AKAP5,PLEKHA5,PSTPIP2,LPCAT2,ARHGAP22,HECW2,COL18A1,SLC7A2,KIF21B,CANX,DENND3,PIBF1,PPP1R9A,DOCK2,CYP26A1,ZSCAN5A,ZNF362,COL22A1,SLC22A17,UNC13B,TACC2,ACVR2A,MYH15,FHIT,CLVS2,MET,SCN2A,SEMA6C,SNAI2,ALG10B,CTH,GLI1,SUSD3,INTU,FER,TMEM67,EVL,THSD4,MVD,CHRNA6,GSTO1,VIM,TTLL7,FRK,JAM3,CENPV,TPK1,BCL11A,ZNF569,ARMC4,RANBP2,NRG3,PTPRJ,LMLN,BACH2,PTK7,GBP1,ITGA2,KCNG1,HGF,DISP1,CTNND2,CNTN1,HEY1,MAN2B2,PCDH18,PRSS16,BMPR2,ARHGEF11,APBB1,LRP4,BLVRB,CLSTN2,COL4A5,RASD1,FAM117B,NOTUM,PPP2R3A,FOXP2,KCNJ4,MAP1A,STC2,DSG2,KIAA0319,TSC22D1,ACTA2,KIAA0408,SH3PXD2B,IQGAP3,ESD,KIAA1211,ATP2B1,CES3,PNMA2,DLGAP1,PPP1R3D,CARD6,HNF4G,ESRRG,GRID1,ASAP3,PRICKLE1,FERMT2,ARHGAP32,C3orf70,SMPDL3B,HOMER3,RERE,MKX,CTIF,ADAMTS17,ICA1,DOCK7,MFSD9,FAT4,FBN1,MPP7,L3MBTL4,ACER2,KIF21A,RPS12,TBC1D4,KIF1B |
| 7.578e-10 | -21.00 | neuron development | biological process | GO:0048666 | 788 | 129 | 17256 | 1658 |
UGT8,KIF5A,GATA3,HDGFL3,ENAH,PRKCA,RAC3,STK24,SKI,CTTN,PACSIN1,ETV1,SLIT2,NKX2-1,ATL1,GPM6A,DCC,LRRK2,FEZ1,TSKU,NCAM2,NCKAP1L,MAP2,SEMA3C,NRP1,UNC5B,MEF2C,BCL11B,EFNB2,LRFN5,GABRB2,OPHN1,SLC1A3,PHGDH,FOXG1,DOK5,CHN1,NUMBL,CNTN4,FRY,SEMA4F,PDZD7,GATA2,FLRT3,PRKG1,GRIP1,NCAM1,STXBP1,GFRA1,LRP12,PAK1,DPYSL5,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,PRDM1,CLN5,BAIAP2,ADGRB3,SH3GL2,MATN2,CLMN,NKX2-8,SEMA3A,SHTN1,EPHA3,NBL1,CELSR3,RBFOX2,PLXNA2,NRXN1,DDR1,SEMA6A,PPP1R9A,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,DAB2IP,ZNF365,NTNG1,SEMA6C,GAB2,EVL,SHANK2,ADCY1,PRKCQ,ATOH1,AMIGO1,JAM3,FGFR1,IRS2,LAMB1,GRB10,MAPK10,COBL,CTNND2,CNTN1,TENM1,TNIK,FARP1,ROBO2,APBB1,LRP4,KIF5C,EPHB1,GDPD5,NEDD4,NEO1,LRRC55,IRX5,MAP1A,LRRN1,SCN1B,SGK1,FIG4,NPTXR,PDLIM7,RAPGEF2,MAP1B,RERE,DOCK7,FAT4,GNAO1,XBP1 |
| 8.118e-10 | -20.93 | CTGCAGY_UNKNOWN | MSigDB lists | CTGCAGY_UNKNOWN | 702 | 120 | 17377 | 1707 |
DOC2A,PHACTR3,NBL1,PCSK1N,ACVR1,CACNG3,DUSP8,FGF13,GRIK2,RBFOX2,SYT12,STAT5B,CADM2,NRXN1,PRR7,IKZF2,NOVA1,SEMA6A,CBLN1,FSTL5,PCDH7,TRPS1,RND2,EPB41L3,SLC22A17,KCNN2,KCNAB1,TACC2,MYO3B,KCNS3,NDUFB8,NBEA,SHF,SLC2A12,PDE4D,PPP2R2B,SCN2A,TMEM132E,ETV1,PDGFRB,GAB2,GLI1,GPM6A,GARS,ATF4,TUBA1A,PNRC1,RNF145,FZD4,PRDM13,DSTN,DEPTOR,FGF12,PNMA6A,COTL1,ATP1B1,FGFR1,GNAI1,BCL11A,ZNF711,KLF12,B3GALT2,ZBTB20,HGF,SPRY4,NR3C2,CTNND2,RAB30,HEY1,LRFN5,FARP1,C1QTNF3,ENO2,KLHL13,SCN8A,BTBD9,FAM81A,PFN2,SATB1,NEDD4,MTUS1,MECOM,MAP1A,CACNB2,FLRT3,TSC22D1,TRIM3,TSPAN13,RNF152,DLGAP1,FGFR4,BDNF,CRIM1,FOXN3,ESRRG,CRIP2,DUSP9,RYR2,SMARCD3,SLITRK5,CTTNBP2NL,RABAC1,MBNL2,HOXA1,MAP1B,DEXI,NSD1,RPL28,MAP2K6,SLCO5A1,NXPH4,GRIN2D,DLG2,GEM,SHOX2,CDH2,ATP2B4,ATP1A3,ABCG1,SNPH |
| 8.495e-10 | -20.89 | RAF_UP.V1_UP | MSigDB lists | RAF_UP.V1_UP | 186 | 47 | 17377 | 1707 |
CREB3L2,ARHGAP26,UGT8,ACSL1,RNF144A,GALNT12,ITGA6,XYLT1,MORC4,RASL11B,HERC5,KCTD12,FAM13A,ABHD6,NEDD4,PLS3,GATA2,BACE2,OPN3,TSPAN12,PDE4D,RRAS2,JAM2,HSPA2,CEBPD,TBC1D8,CYP1B1,MICAL2,ABCC4,SKAP2,CRIM1,TES,FERMT2,COTL1,NPC2,C4orf19,ASPH,HEG1,TBC1D2,GNAI1,GPR37,CAMK2N1,SLC2A6,HPGD,CLMN,SERPINI1,GRB10 |
| 8.695e-10 | -20.86 | GO_NEURON_PROJECTION | MSigDB lists | GO_NEURON_PROJECTION | 907 | 146 | 17377 | 1707 |
DOC2A,FGF13,PRSS12,GRIK2,KIF5A,ASS1,NDRG2,CADM2,ABAT,BCAN,DNER,RAC3,NCS1,TUBB4A,BAG3,KCNAB1,KCNN2,LIN7A,CTTN,PACSIN1,DBN1,ATL1,GPM6A,KCNIP3,ATF4,DCC,WLS,ANK2,LRRK2,FEZ1,PRKAR2B,KCND3,TRIM9,NCAM2,MAP2,PLK2,TMOD2,PPARGC1A,NRP1,MAGI2,LZTS1,BCL11B,SCN8A,OPHN1,SLC1A3,APBA1,PFN2,CA2,CNTN4,FLRT3,GRIP1,MPDZ,BNIP3,STXBP1,CHRM3,ZNF385A,PAK1,DPYSL5,UNC5C,DISC1,KCNQ3,MYO10,HOMER2,SDC3,SNAP25,CPEB1,BAIAP2,DAGLA,RPL28,PTPRN2,SEMA3A,MME,DNM3,AKAP5,CANX,NRXN1,SEMA6A,PPP1R9A,TIAM2,CTNNA2,CCDC120,EPB41L3,NELL2,UNC13B,CHRNA5,GPRIN1,DAB2IP,MARCKS,SCN2A,KCNB2,SCN3A,FZD1,GARS,SHANK2,PREX1,NLGN4X,VIM,GSTO1,AMIGO1,TTLL7,GABARAPL1,SNCA,CAMK2N1,WFS1,ITGA2,PAM,BMPR1A,SEPT5,CTTNBP2,STON2,COBL,PSPH,CTNND2,MYO1D,FARP1,BMPR2,ROBO2,BACE1,LRP4,EPS8,APBB1,KIF5C,GABRG2,P2RY1,EPHB1,KCNC4,GDPD5,ARHGAP44,RGS17,KCNJ4,SCN1B,SGK1,ATP2B1,PTPN13,RAPGEF2,ARHGAP32,PALLD,MAP1B,DOCK7,ICA1,GNAO1,DLG2,KIF1B,ATP2B4,SNPH,ATP1A3 |
| 9.170e-10 | -20.81 | GCANCTGNY_V$MYOD_Q6 | MSigDB lists | GCANCTGNY_V$MYOD_Q6 | 852 | 139 | 17377 | 1707 |
DOC2A,PHACTR3,PPP4R4,ACVR1,FGF13,HEBP1,GATA3,CADM2,IKZF2,NOVA1,SLC9A7,ANKRD42,TUBB4A,FBXO32,KCNN2,MPPED2,KCNS3,NDUFB8,COL19A1,JAKMIP2,VWA5A,ETV1,SLIT2,NKX2-1,KCNIP3,COL4A3,ANK2,DEPTOR,FGF17,KLF12,B3GALT2,ADRB1,DNHD1,PPARGC1A,NEUROG2,LRFN5,SCN8A,TJP1,TNFRSF19,MTUS1,DDIT4,NUMBL,IGF1R,GATA2,CACNB2,FLRT3,MYC,FAM107B,ADCY6,NCAM1,SLCO4C1,TSPAN9,GFRA1,ZNF385A,NDUFA4L2,DPYSL5,MID2,BDNF,SLC37A1,SLC27A2,COL4A4,PARD3B,PACSIN3,WDR25,WWC1,PRDM1,RABAC1,MBNL2,NEGR1,MMP15,PELI2,HEYL,MPP2,SQLE,EML5,ID1,DNM3,PCSK1N,MORC4,NTRK3,TDRKH,GRK6,RADIL,PRR7,COL22A1,SPEG,UNC13B,SLC22A17,DACT1,ZNF521,MAP7,NBEA,DAB2IP,MYT1,IGFBP3,GAB2,GAPDH,PRDM13,FGF12,ATP1B1,FGFR1,PTPRJ,PRKCB,ITGA2,PAM,COBL,CCDC148,IGFBP6,BMPR2,PKN1,BEX2,BMP6,PPP2R3A,FOXP2,LRRN1,MAP1A,PCBP4,RASD2,TSPAN13,FIG4,ERRFI1,GFI1,BCL7A,USP2,CYTH3,CRIP2,PRICKLE1,LRAT,FGR,TUFT1,SVIL,GRIN2D,DLG2,RPL4,TNFRSF17,SHOX2,KIF1B,ATP1A3,SNPH |
| 9.363e-10 | -20.79 | haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_neoplasm | 11378 | 1222 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,TXNDC5,PPP2R2B,COG3,CPE,DCC,KLHL23,EXOC6B,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,ENPP1,ATP7B,MAP9,BDH2,ERCC5,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,TLR3,ALDH1L1,FAM133A,DNAH5,ZNF365,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,CCDC148,WDR17,GCAT,FZD8,ESRP1,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,MN1,RAB6B,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,PHACTR3,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,ITGB3,JAKMIP2,TMEM132E,ENO1,PGBD5,ZNF391,DBN1,MARK1,ATF4,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,INSIG1,KLF12,ERN1,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,DOK5,FHOD3,NUMBL,ZNF440,FRAS1,SMTN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,OBSCN,SDK1,KHDRBS2,NEGR1,TBC1D2,GRIK4,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,RPS13,INTU,TDRD3,ACO1,RNF125,CHRNA6,PTPRJ,RNF217,PTPRS,MAOA,HGF,CTNND2,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,MCTP2,USP30,SLC35F1,FOXP2,TTC1,GTF2F2,TSC22D1,SGK1,KIAA0408,SYK,DUSP1,LRRIQ1,FERMT2,PRICKLE1,PALLD,ILDR2,MGMT,SMPDL3B,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,ZFYVE28,SERINC2,NDUFB8,KCNS3,GLDC,GDAP1,ACVR1C,WISP3,LRMP,BNIP3L,EFHC1,GNAI1,SH3RF1,ENPP6,BMP1,MAPK13,SERPINI1,DSEL,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,ST6GAL1,DHCR24,LRRC49,APBA1,TNFRSF19,MTUS1,ABLIM1,RALGPS2,SLC7A11,ADCK1,MYC,PRKG1,SREBF1,CPXM2,GRIP1,FAM155A,PRR16,COL9A2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,PLEKHH2,CECR2,THBS4,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,SPEG,ASNS,ZNF438,POU5F1B,PDE4D,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATP10D,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,STON2,MID1,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,INPP1,ATXN7L1,RASSF8,LRRC55,AFF2,GPR155,DYNC2H1,TBC1D9,B4GALT6,TMC7,VAV3,SLC40A1,ARHGEF28,SH3BP2,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,LARP1,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,HMCN1,CHST10,F3,ADPRHL1,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,CNNM2,TRPC1,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,JPH1,TMEM47,SGK2,GPRC5B,FAM114A2,CCDC169,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,RHOBTB1,BVES,STXBP6,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,GSTM4,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,XKR4,DMXL2,PSTPIP2,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,PDZD8,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,FHIT,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,BATF3,BCL11A,ZNF569,ARMC4,ZNF93,TRIM34,RBPMS2,TMPRSS9,RGS10,RNF130,MAST1,ENO2,ARHGEF11,TSPAN15,CMTM8,SSX1,COL4A5,IGF2BP2,FAM174B,SEL1L3,BMP6,SYDE2,RAB11FIP5,FSD1,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,CADM2,STAT5B,DOCK3,NHP2,CA8,NOS1AP,EYA4,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,MEIS2,WLS,GJB2,CAP2,TGFA,ELMOD1,F12,MFSD6,CA13,ALDOA,ARHGAP28,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,SYCP2,KIAA1671,FAM189A1,BACE2,CACNB2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,RPS23,FADS1,BDNF,SLC37A1,MYO10,STAT4,RYR2,CALCRL,PLS1,C1R,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,RGS20,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,JAKMIP3,SCN3A,DOCK8,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,TTC28,FGFR1,METAP1D,IQCK,IQCH,GYPC,INPP4B,PLEKHG1,ALG11,TNFSF15,DBP,PLD5,KLHL31,FARP1,TMEM132C,ROBO2,C1QTNF3,IPO5,NKAIN2,CREB5,PKN1,KCNC4,COL27A1,NEO1,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,DCBLD1,NBPF4,TRIM2,FAM227A,FHDC1,LILRB1,ASS1,SYT14,NOVA1,FSTL5,KCNN2,KCNAB1,HPS1,MARVELD2,LIN7A,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,GCNT2,ABCC4,GDPD1,TCERG1L,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,ZCCHC24,UBASH3B,SETBP1,MLC1,IL18R1,PGAP1,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,UNC5C,MID2,RNF170,SLC27A2,SPATA13,TCEA3,TMTC4,PPFIA4,WDR25,PDE8A,TEX9,MAPKAPK2,ATPAF2,CSF1,MFSD2A,PANK3,MME,CFH,AKAP5,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,LPIN3,SEZ6L2,PCLO,CYP26A1,TBC1D19,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,GBP1,PTK7,ABI3,ITGA2,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,COL9A3,IL32,RUSC2,APBB1,GABRG2,SELL,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,DLGAP1,MICAL2,PPP1R3D,NUAK2,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,TBC1D4,FILIP1,CGN,MYCBP2,ACVR1,LANCL3,SIDT1,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,RAC3,STK24,NCS1,SLC22A18,CFHR1,FAM168A,CHRDL1,ATRNL1,GSTM3,VWA5A,TBC1D8,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,TNS1,ACVR2B,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ZHX3,PTPRD,SCN8A,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,OPN3,PRELID1,SLC16A9,TSPAN12,MPDZ,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,COL4A4,CCDC85A,C4orf19,PLCB1,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,RASAL2,ELOVL4,RNF144A,GPR65,ZNF311,CHUK,SPATS2L,ZNF827,TMEM53,NBEA,SCRN1,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,MAP3K21,GRB10,CTTNBP2,NR3C2,THOC3,DENND5B,WASF3,ANO10,MXI1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,ARAP2,SYNPO2,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,GPLD1,FGR,OR2T33,NUTM2A,TUFT1,MYOM2,NUDT17,ATP1A3,SLC43A1,EXPH5,MPZL3,KIF5A,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,CYP51A1,ARHGEF10L,RTN1,LRRC6,GRHL1,AKAP7,SLC10A7,POF1B,SLC2A12,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,CAPN5,ZNF565,ROR1,SERGEF,EML1,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,RIMKLA,ELOVL7,CYP4V2,LAMC3,GALNT13,SATB1,CD7,CA2,RPS11,FAM107B,NCEH1,MORN4,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,MSTN,PARD3B,EDEM3,WWC1,LHPP,PRDM1,B4GALNT3,FCHO2,HK2,RAI14,DIRC2,CREB3L2,EML5,NEK10,ZSWIM5,CELSR3,IL15,PLEKHA5,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,ZNF460,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,DOCK5,TTLL7,C1orf174,WARS,TPK1,LMLN,BACH2,SOHLH2,DISP1,LIFR,OR51B5,TNIK,CLGN,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,ESRRG,CYTH3,GRID1,OGDHL,MEI1,PHACTR2,ARHGAP32,ZFPM2,C3orf70,MAP1B,RERE,GPR37,ADAMTS17,NACC2,MPP7,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SLC16A10 |
| 9.694e-10 | -20.75 | MANALO_HYPOXIA_UP | MSigDB lists | MANALO_HYPOXIA_UP | 199 | 49 | 17377 | 1707 |
CREB3L2,MXI1,ENO2,ZNF395,RHOBTB1,COL18A1,CHSY1,ITPR2,GAS6,DDIT4,FKBP9,RPS6KA2,BACE2,STC2,OPN3,BCL6,MARCH3,BNIP3,LIMCH1,SMAD6,MAST4,IGFBP3,VEGFC,MN1,PXN,ALDH2,DCHS1,VLDLR,BNIP3L,AK4,TNS1,LEPR,GLCE,TSKU,TCF7L1,ENPP1,GYPC,PLOD2,P4HA2,PELI2,LAMB1,RAI14,PAM,INHBE,SLCO5A1,P4HA1,TPM1,SHOX2,CDH2 |
| 1.005e-09 | -20.72 | cervix | COSMIC cancer mutations | cervix | 12130 | 1291 | 17385 | 1698 |
TRIM16L,THOC5,ADAL,CNTNAP3,RECK,MCOLN3,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,SKI,TXNDC5,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,ST6GALNAC3,SHISA2,ZBBX,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,RPL28,QPCTL,CLMN,CDH2,DOCK9,TFCP2L1,ABHD13,ADD2,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,ARHGAP21,WFS1,LAMB1,FAM149A,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,BACE1,PLAG1,BIK,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RASA3,ATP11A,NSD1,RPL12,PCDHB7,SRD5A3,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,RPS6KA2,CPVL,AADAT,SEC16B,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZIC2,DOK5,SPIRE1,FHOD3,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,NIPAL2,VGLL4,CKAP4,DPYSL5,STRADB,SLITRK5,MAFB,OBSCN,SDK1,GPR19,NEGR1,GRIK4,SLC2A6,FBRSL1,PLD1,SEMA3A,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,IDI1,TACC2,BCL6,ZDHHC23,MYH15,RPS13,HRASLS,INTU,LRRC8B,TDRD3,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,CTNND2,HEY1,TENM1,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,SLC35F1,FOXP2,TFAP2A,GTF2F2,TSC22D1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,DOCK7,FBN1,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,ERGIC1,ACVR1C,WISP3,KLHL3,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,MTUS1,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,COL9A2,GPR161,PTCH2,DISC1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,SLFN5,NBL1,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,POU5F1B,ALDOC,SHF,GATM,GAB2,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATP1B1,ATOH1,PYGO1,ATP10D,ZNF711,POPDC3,CCNA1,HPGD,BMPR1A,STON2,PURG,MID1,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,TPD52L1,INPP1,PHLDA2,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,ZDHHC15,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,GSN,TMEM150B,GPRC5B,FAM114A2,OXTR,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,CHADL,CHSY1,SPINK5,PCDHB14,RNF141,EEF2,LIMCH1,RNF148,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,GSTM4,SLC46A3,HERPUD1,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,PTPRU,MVD,C3orf52,TCEAL3,CD40,CENPV,BATF3,BCL11A,ZNF569,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,TMPRSS9,RNF130,MAST1,ENO2,ARHGEF11,TSPAN15,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,SEL1L3,SYDE2,RAB11FIP5,FSD1,KCNJ4,SCN1B,PRKCD,STC2,CCDC122,MARCH3,AFAP1L2,IPCEF1,PNMA2,CARD6,CRIM1,SYBU,ASAP3,GALNT14,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,AASS,PRSS12,DNAJC3,STAT5B,DOCK3,CA8,NOS1AP,EYA4,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,WLS,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,TTC30B,SYCP2,RSL24D1,KIAA1671,FAM189A1,BACE2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,TAF4B,MBNL2,DHX32,TMCO3,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,JAKMIP3,ARL4D,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,TTC28,METAP1D,FGFR1,IRS2,IQCH,PEMT,GPR160,INPP4B,PLEKHG1,PAM,KLHL31,SERINC5,FARP1,TMEM132C,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,LCA5,RAPGEF2,MCF2L2,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,NMNAT3,TRIM2,FAM227A,SYT12,FHDC1,LILRB1,ASS1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,SLC3A2,ABCC4,PLEKHA1,TCERG1L,BATF,NT5DC2,INHBC,MAP2,P4HA2,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,PRKAA2,ITPRIP,UBASH3B,SETBP1,IL18R1,PGAP1,HSPA12B,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,FBXL2,PAK1,CHSY3,FGFR4,MID2,SLC27A2,HOMER2,SPATA13,TCEA3,TMTC4,PPFIA4,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CBLN1,CYP26A1,TBC1D19,SLC22A17,LHX6,ZDHHC6,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,EVL,THSD4,FGF12,GSTO1,FRK,JAM3,SMAD3,RANBP2,NRG3,ANKRD31,GBP1,PTK7,ITGA2,KCNG1,ABI3,TTC39A,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,GRB14,RUSC2,APBB1,GABRG2,SELL,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,NUAK2,FNDC3A,NPDC1,TMEM237,FAT4,L3MBTL4,ZNF214,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,PPP4R4,LANCL3,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,ENAH,ADAMTS6,DACH2,RAC3,AARS,CFHR1,FAM168A,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,GPC6,AHRR,SFXN1,NCKAP1L,ENTPD7,RASGRF2,CCBE1,TANC2,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,MECOM,MCOLN2,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,SLC16A9,MPDZ,SAMD13,RIMS2,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,RASAL2,ELOVL4,GPR65,ZNF311,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,ZNF827,NELL2,STARD4,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,ZNF396,PRKCB,MAP3K21,KLF5,GRB10,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,FIG4,SEPT3,SMPDL3A,ARAP2,SYNPO2,CACNA1E,MPP1,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,EXPH5,MVK,KIF5A,UGDH,ANKRD18A,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,QPRT,RTN1,ARHGEF10L,GRHL1,AKAP7,SLC2A12,PCOLCE2,FANK1,OR2W3,SLIT2,RASGRP1,ATL1,GPM6A,ZNF565,ROR1,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,RIMKLA,CYP4V2,LAMC3,ATP6V1E2,GALNT13,SATB1,DDIT4,OTUD1,CA2,FAM107B,EBF4,BARX1,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,PARD3B,EDEM3,DUSP9,WWC1,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,IL15,PLEKHA5,MORC4,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,GULP1,MDH1B,WWC2,POU2F2,MET,HSPA2,SUSD3,DPP10,FER,PHLDB2,SLC39A8,TES,TTLL7,DOCK5,C1orf174,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,REL,LRP4,NSUN6,CLSTN2,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,DHRS12,IQGAP3,TNFRSF11A,RIN2,MSX1,ESRRG,CYTH3,GRID1,OGDHL,PRRG1,MEI1,MARS,AGAP2,PHACTR2,ARHGAP32,ZFPM2,C3orf70,MAP1B,RERE,GPR37,ADAMTS17,MYADM,NACC2,MPP7,PRCP,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SNPH |
| 1.047e-09 | -20.68 | GO_TISSUE_DEVELOPMENT | MSigDB lists | GO_TISSUE_DEVELOPMENT | 1437 | 210 | 17377 | 1707 |
EXPH5,ACVR1,LGR4,ACTL8,MCOLN3,GATA3,STAT5B,DNER,CACNB4,AARS,TRPS1,PLS3,SKI,EPCAM,TGFBR3,KCNAB1,EOMES,GRHL1,DLX6,MARVELD2,ITGB3,RAP2A,GSTM3,COL19A1,SLIT2,PRKACB,PDGFRB,POU3F3,NKX2-1,CYP1B1,SMAD9,KLHL3,GJB2,WLS,CAPN5,YAP1,ACVR2B,SAV1,ARHGEF26,DYRK1B,GSN,ENPP1,HLF,BMP1,BDH2,SEMA3C,DLX2,TMEFF2,PPARGC1A,NRP1,TPM1,MAGI2,MEF2C,BCL11B,EFNB2,LATS2,SEMA6B,RUNX2,FN1,CELSR1,LGALS3,BVES,ITGA6,DHCR24,TJP1,CHSY1,GPSM2,SATB1,PHGDH,SPINK5,TNFRSF19,FHOD3,CA2,SEMA4F,EEF2,SLC7A11,PDZD7,GATA2,FLRT3,FRAS1,MYC,LRP6,TSPAN12,BARX1,EPB41L5,PAK1,PTCH2,ENAM,MSTN,DCHS1,ARID5B,FHL2,RYR2,PRDM1,SDK1,MMP15,PLAGL1,CSF1,HEYL,CECR2,WDR19,HOXD13,CDH2,SEMA3A,SFN,SIX2,CREB3L2,PLA2G4A,TFCP2L1,ID1,ZNF516,ST14,PLXNA2,RGS20,COL18A1,PKP2,NTRK3,DDR1,SEMA6A,SETDB2,ALDOC,KAZN,DACT1,ACVR2A,MYH15,MARCKS,PDE4D,MET,SERPINH1,SNAI2,SEMA6C,GLI1,FZD1,INTU,MYLK3,SOX21,NKX3-2,PRKCQ,WNT11,VIM,CBY1,SATB2,ATF3,ATOH1,DSP,FGFR1,GJC1,SMAD3,MSC,IKZF3,PTK7,ITGA2,LAMB1,WWTR1,PTPRS,KLF5,HGF,BMPR1A,ATG5,KLHL31,COBL,HEY1,BMPR2,EDA2R,ROBO2,LRP4,OVOL2,BMP6,NEDD4,PPP2R3A,COL27A1,NKX6-1,FOXP2,DSG2,STC2,TFAP2A,ACTA2,SH3PXD2B,ERRFI1,SMAD6,SPRY2,DUSP1,B9D1,VEGFC,MICAL2,SLC40A1,MSX1,KDM5B,RAPGEF2,PRICKLE1,ZFPM2,FNDC3A,PALLD,MGMT,GPLD1,HEG1,DKK1,CEBPB,PTPRC,ID3,MYADM,FAT4,XBP1,TUFT1,SVIL,PAX9,BMP4,SHOX2,FOXA1,BTRC |
| 1.069e-09 | -20.66 | GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_MULTICELLULAR_ORGANISMAL_DEVELOPMENT | 1599 | 229 | 17377 | 1707 |
ACVR1,LGR4,TRIM16,FGF13,GATA3,LILRB1,STAT5B,PRKCA,RAC3,STK24,NCS1,F3,TRPS1,SKI,RND2,EOMES,RAP2A,CTTN,PACSIN1,TLR4,SLIT2,RASGRP1,PRKACB,PDGFRB,NKX2-1,CYP1B1,DBN1,MEIS2,GCNT2,COL4A3,ACVR1C,DCC,LRRK2,YAP1,FEZ1,ACVR2B,ROR1,SAV1,GPC6,ENPP1,GPRC5B,HPSE,NCKAP1L,CCBE1,PLK2,TNFRSF1A,BMP1,SEMA3C,INPP5F,DLX2,OXTR,NRP1,TNFSF4,VASH2,MAGI2,MLLT3,LZTS1,MEF2C,UST,BCL11B,EFNB2,SEMA6B,RUNX2,CELSR1,LGALS3,FN1,PTPRD,UBASH3B,CHADL,SPINK5,CHN1,EFEMP1,NUMBL,CA2,CNTN4,SEMA4F,GATA2,APLF,FLRT3,MYC,PRELID1,LRP6,ADCY6,TSPAN12,RIMS2,GPR161,NOS3,HMGCR,PTCH2,EPB41L5,BDNF,DISC1,PNP,SLITRK2,MSTN,VLDLR,SMARCD3,SLITRK5,MAFB,PRDM1,SDK1,SNAP25,PLCB1,CPEB1,BAIAP2,NEGR1,HEYL,CSF1,THBS4,SFMBT1,HOXD13,CDH2,SEMA3A,TESC,SFN,SIX2,EPHA3,PLA2G4A,NBL1,DNM3,ID1,CELSR3,IL15,AKAP5,RBFOX2,PLXNA2,BCL6B,NTRK3,NRXN1,PPP1R9A,CBLN1,SEMA6A,SCIN,TLR3,DACT1,BCL6,ACVR2A,DAB2IP,MARCKS,ZNF488,SEMA6C,SNAI2,CTH,FZD1,GLI1,SSH3,PHLDB2,CSN2,ADM2,FZD4,NKX3-2,PTPN6,PREX1,VIM,WNT11,SYNJ2BP,AMIGO1,ATOH1,CD40,FGFR1,BCL11A,WARS,SMAD3,CXCL10,NRG3,IKZF3,PRKCB,PTK7,WWTR1,HGF,BMPR1A,COBL,HEY1,CNTN1,WASF3,TNIK,BMPR2,ROBO2,PLAG1,CD276,LRP4,APBB1,CLSTN2,OVOL2,GAS6,EPHB1,GDPD5,BMP6,PHLDA2,PPP2R3A,NEDD4,HOPX,NKX6-1,FOXP2,LRRN1,SCN1B,KIAA0319,TFAP2A,SGK1,PRICKLE2,FIG4,IQGAP3,ERRFI1,GFI1,SYK,SLC45A3,FES,TRPM4,VEGFC,MSX1,USP2,KDM5B,RAPGEF2,PRICKLE1,ZFPM2,MAP1B,DKK1,CEBPB,DDAH1,DOCK7,MYADM,FAT4,XBP1,PAX9,BMP4,SHOX2,FOXA1,DDIT3,TLL2 |
| 1.089e-09 | -20.64 | ZHAN_MULTIPLE_MYELOMA_MS_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MS_UP | 44 | 20 | 17377 | 1707 |
MARK1,CLGN,MYO10,KLHL13,FZD8,PALLD,JAM3,SLC22A17,BACE2,DSG2,ZNF521,RUNDC3B,DSEL,NAP1L3,WWC2,VWA5A,MYRIP,SPRY2,LRP12,PCSK5 |
| 1.139e-09 | -20.59 | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | 140 | 39 | 17377 | 1707 |
CARS,MXI1,IL15,SEC24D,ZNF215,CHAC1,DDIT4,ASNS,SLC7A11,PMAIP1,GAB2,IGFBP3,DUSP1,MSX1,SLC3A2,CD55,ATF4,GARS,TUBA1A,PNRC1,TES,ARID5B,NFE2L1,ATF3,MARS,PALLD,FNDC3A,MBNL2,STEAP1,ISG20,GABARAPL1,CEBPB,TMCO3,TRIB3,RND3,P4HA2,BBC3,DDIT3,FOXA1 |
| 1.139e-09 | -20.59 | serous_carcinoma | COSMIC cancer mutations | serous_carcinoma | 11298 | 1214 | 17385 | 1698 |
ARHGAP26,THOC5,GRIK2,CNTNAP3,RECK,TUBE1,ALG1L,CTBP2,BCAN,KIAA1217,ABHD6,SKI,RAP2A,PPP2R2B,TMEM37,CPE,POU3F3,DCC,DSTN,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,ENPP1,WIPF3,ATP7B,MAP9,ERCC5,DIRAS1,INPP5F,TMOD2,DNHD1,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,FOXG1,BBS9,CHN1,FRY,APLF,FLRT3,SRGAP1,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,CLN5,SPATA7,CACHD1,TEX15,GSTO2,CLMN,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,DNAH5,ZNF365,MYT1,ANKRD18B,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,CCDC148,ANKRD13B,WDR17,CKAP2,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,GHR,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,MN1,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,NEK11,BMP4,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,TMEM86A,ITGB3,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,SESN1,CRYBG3,DYRK1B,TRIM9,TCF7L1,KLF12,ERN1,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,ZNF215,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,STRADB,SLITRK5,OBSCN,SDK1,KHDRBS2,GPR19,NEGR1,TBC1D2,GRIK4,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,PPP1R9A,SEMA6A,DDX60L,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,INTU,CSN2,LRRC8B,TDRD3,ACO1,CHRNA6,VIM,IFT81,PTPRJ,PTPRS,MAOA,HGF,SUSD4,CTNND2,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,SLC35F1,FOXP2,TTC1,KCNMB3,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,TRPS1,TYMP,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,KLHL3,LRMP,EFHC1,ZDHHC14,BMP1,MAPK13,DSEL,SPRY4,NRP1,SPOCK3,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,LRRC49,APBA1,MTUS1,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,CPXM2,GRIP1,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,CECR2,THBS4,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,NBL1,TCTN2,ST14,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,SHANK2,PREX1,NLGN4X,SATB2,CBY1,PYGO1,ATP1B1,ATP10D,C9orf116,SNCA,ZNF711,IKZF3,POPDC3,CCNA1,BMPR1A,COBL,PURG,MID1,HACE1,MYO1D,IGFBP6,EPS8,PRSS35,HERC5,NDFIP2,INPP1,RASSF8,LRRC55,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,TMC7,VAV3,SLC40A1,ALDH2,SH3BP2,PXN,AGPAT4,PTPN13,TMEM126A,ZDHHC15,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,LARP1,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,PPM1E,SIPA1L2,ABI3BP,ANKFN1,CNNM2,TRPC1,CTTN,MYRIP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,SGK2,GSN,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,RHOBTB1,CHADL,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,LIMCH1,RNF148,LRP3,SNX7,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,TMEM154,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,PIBF1,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,MVD,TCEAL3,AMIGO1,CD40,BCL11A,ARMC4,KPNA3,TRIM34,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,ARL15,TNFSF13B,COL4A5,FAM117B,OVOL2,BMP6,SYDE2,RAB11FIP5,FSD1,KCNJ4,SCN1B,PRKCD,STC2,MARCH3,AFAP1L2,IPCEF1,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,LEPR,CTIF,DPY19L2,MFSD9,EDA,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,FAM102B,CADM2,STAT5B,DOCK3,NHP2,EYA4,EPDR1,PCDH7,BAG3,TGFBR3,DNAH6,FAAH2,PPFIA2,KLHL29,TSHR,MEIS2,SMAD9,WLS,CAP2,MFSD6,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,LPP,CARS,LATS2,STOX2,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,FAM189A1,BACE2,ZIC5,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,OR11H4,DHX32,BEX4,TMCO3,ADAMTS3,EMILIN2,CDH17,FBXO27,TRPC3,CSRP2,ZNF516,DNM3,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,RGS20,PKP2,NRXN1,LCP2,COLEC10,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,PJA1,FAM155B,JAKMIP3,ARL4D,DOCK8,SCN3A,PERP,SSH3,GARS,RNF145,FZD4,KCNH5,TTC28,FGFR1,METAP1D,IQCK,IQCH,ZNF697,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,RCN3,ALG11,P4HA1,PLD5,KLHL31,SERINC5,FARP1,ROBO2,IPO5,C1orf226,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,FES,BCL7A,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,AKT3,OSBPL5,SLCO5A1,HK1,DOCK6,BTRC,DCBLD1,TRIM2,SYT12,FHDC1,LILRB1,ASS1,SYT14,NUP62CL,NOVA1,FSTL5,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,LIN7A,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,SLC3A2,ABCC4,PLEKHA1,TCERG1L,BATF,PLEKHB1,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ZCCHC24,UBASH3B,RASL11B,SETBP1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,PDE10A,SAMD11,SLCO4C1,PAK1,CHSY3,FGFR4,UNC5C,MID2,SLC27A2,SPATA13,TMTC4,PPFIA4,PDE8A,MAPKAPK2,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,AVPI1,CFH,RBFOX2,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,LPIN3,SEZ6L2,PCLO,CBLN1,CYP26A1,FAM131B,TBC1D19,SLC22A17,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,TMEM67,UROS,THSD4,FGF12,FBXO36,FRK,JAM3,C4BPB,RANBP2,NRG3,GBP1,PTK7,KCNG1,ITGA2,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SFXN3,PPP2R3A,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,NUAK2,FNDC3A,MKX,FAT4,L3MBTL4,FMO4,DLG2,PAX9,THAP10,TBC1D4,FILIP1,CGN,MYCBP2,ACVR1,PPP4R4,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,STK24,NCS1,MOK,SLC22A18,CFHR1,SLC16A2,CHRDL1,ATRNL1,SP140,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,KLHL4,DNAJC6,DEPTOR,TNS1,ACVR2B,ARHGEF26,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,SCN8A,OPHN1,GTF2IRD1,ISYNA1,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,MECOM,MCOLN2,NAV1,CNTN4,PIK3AP1,PDZD7,RUNDC3B,OPN3,SLC16A9,TSPAN12,MPDZ,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,RASAL2,ELOVL4,RNF144A,OTX1,KCTD12,CHUK,SPATS2L,TBC1D30,ZNF827,TMEM53,NELL2,STARD4,NBEA,SCRN1,DAB2IP,NAP1L3,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,KLF5,GRB10,CTTNBP2,NR3C2,KCTD1,DENND5B,WASF3,ANO10,ANKRD13D,ATP9A,GABRR2,RGS7,GDPD5,NEDD4,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,ZIC1,GPLD1,FGR,OR2T33,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,NUDT17,ATP1A3,SLC43A1,EXPH5,MVK,KIF5A,UGDH,ANKRD18A,DNER,CACNB4,IKZF2,KREMEN1,SLCO3A1,CYP51A1,ARHGEF10L,RTN1,LRRC6,GRHL1,AKAP7,DLX6,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,CAPN5,ZNF565,ROR1,EML1,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,RIMKLA,ELOVL7,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,EBF4,NCEH1,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,RAI14,HK2,EGFL7,CREB3L2,CXCR5,EML5,NEK10,CELSR3,PLEKHA5,MORC4,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,STEAP3,GULP1,MDH1B,WWC2,POU2F2,MET,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,TES,DOCK5,TTLL7,C1orf174,WARS,TPK1,LMLN,BACH2,DISP1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,NKX6-1,CHN2,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,ESRRG,CYTH3,GRID1,OGDHL,PRRG1,MEI1,MARS,PHACTR2,AGAP2,ARHGAP32,ZFPM2,C3orf70,MAP1B,RERE,GPR37,ADAMTS17,MYADM,NACC2,MPP7,MAP2K6,THSD7B,KIAA0513,KIF21A,MMP16,SLC16A10,SNPH |
| 1.260e-09 | -20.49 | cervix-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-squamous_cell_carcinoma | 12126 | 1290 | 17385 | 1698 |
TRIM16L,THOC5,ADAL,CNTNAP3,RECK,MCOLN3,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,SKI,TXNDC5,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,ST6GALNAC3,SHISA2,ZBBX,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,RPL28,QPCTL,CLMN,CDH2,DOCK9,TFCP2L1,ABHD13,ADD2,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,ARHGAP21,WFS1,LAMB1,FAM149A,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,BACE1,PLAG1,BIK,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RASA3,ATP11A,NSD1,RPL12,PCDHB7,SRD5A3,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,RPS6KA2,CPVL,AADAT,SEC16B,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZIC2,DOK5,SPIRE1,FHOD3,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,NIPAL2,VGLL4,CKAP4,DPYSL5,STRADB,SLITRK5,MAFB,OBSCN,SDK1,GPR19,NEGR1,GRIK4,SLC2A6,FBRSL1,PLD1,SEMA3A,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,IDI1,TACC2,BCL6,ZDHHC23,MYH15,RPS13,HRASLS,INTU,LRRC8B,TDRD3,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,CTNND2,HEY1,TENM1,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,SLC35F1,FOXP2,TFAP2A,GTF2F2,TSC22D1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,DOCK7,FBN1,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,ERGIC1,ACVR1C,WISP3,KLHL3,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,MTUS1,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,COL9A2,GPR161,PTCH2,DISC1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,SLFN5,NBL1,TCTN2,RHOD,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,POU5F1B,ALDOC,SHF,GATM,GAB2,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATP1B1,ATOH1,PYGO1,ATP10D,ZNF711,POPDC3,CCNA1,HPGD,BMPR1A,STON2,PURG,MID1,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,KIF5C,TPD52L1,INPP1,PHLDA2,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,ZDHHC15,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,GSN,TMEM150B,GPRC5B,FAM114A2,OXTR,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,CHADL,CHSY1,SPINK5,PCDHB14,RNF141,EEF2,LIMCH1,RNF148,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,GSTM4,SLC46A3,HERPUD1,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,PTPRU,MVD,C3orf52,TCEAL3,CD40,CENPV,BATF3,BCL11A,ZNF569,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,TMPRSS9,RNF130,MAST1,ENO2,ARHGEF11,TSPAN15,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,SEL1L3,SYDE2,RAB11FIP5,FSD1,KCNJ4,SCN1B,PRKCD,STC2,CCDC122,MARCH3,AFAP1L2,IPCEF1,PNMA2,CARD6,CRIM1,SYBU,ASAP3,GALNT14,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,AASS,PRSS12,DNAJC3,STAT5B,DOCK3,CA8,NOS1AP,EYA4,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,WLS,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,TTC30B,SYCP2,RSL24D1,KIAA1671,FAM189A1,BACE2,ZIC5,PRELID2,LOXL4,ST8SIA1,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,SLC37A1,PNP,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,TAF4B,MBNL2,DHX32,TMCO3,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,JAKMIP3,ARL4D,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,TTC28,METAP1D,IRS2,IQCH,PEMT,GPR160,INPP4B,PLEKHG1,PAM,KLHL31,SERINC5,FARP1,TMEM132C,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,LCA5,RAPGEF2,MCF2L2,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,NMNAT3,TRIM2,FAM227A,SYT12,FHDC1,LILRB1,ASS1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,SLC3A2,ABCC4,PLEKHA1,TCERG1L,BATF,NT5DC2,INHBC,MAP2,P4HA2,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,PRKAA2,ITPRIP,UBASH3B,SETBP1,IL18R1,PGAP1,HSPA12B,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,FBXL2,PAK1,CHSY3,FGFR4,MID2,SLC27A2,HOMER2,SPATA13,TCEA3,TMTC4,PPFIA4,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CBLN1,CYP26A1,TBC1D19,SLC22A17,LHX6,ZDHHC6,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,EVL,THSD4,FGF12,GSTO1,FRK,JAM3,SMAD3,RANBP2,NRG3,ANKRD31,GBP1,PTK7,ITGA2,KCNG1,ABI3,TTC39A,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,GRB14,RUSC2,APBB1,GABRG2,SELL,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,NUAK2,FNDC3A,NPDC1,TMEM237,FAT4,L3MBTL4,ZNF214,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,PPP4R4,LANCL3,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,ENAH,ADAMTS6,DACH2,RAC3,AARS,CFHR1,FAM168A,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,GPC6,AHRR,SFXN1,NCKAP1L,ENTPD7,RASGRF2,CCBE1,TANC2,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,MECOM,MCOLN2,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,SLC16A9,MPDZ,SAMD13,RIMS2,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,RASAL2,ELOVL4,GPR65,ZNF311,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,ZNF827,NELL2,STARD4,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,ZNF396,PRKCB,MAP3K21,KLF5,GRB10,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,FIG4,SEPT3,SMPDL3A,ARAP2,SYNPO2,CACNA1E,MPP1,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,EXPH5,MVK,KIF5A,UGDH,ANKRD18A,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,QPRT,RTN1,ARHGEF10L,GRHL1,AKAP7,SLC2A12,PCOLCE2,FANK1,OR2W3,SLIT2,RASGRP1,ATL1,GPM6A,ZNF565,ROR1,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,RIMKLA,CYP4V2,LAMC3,ATP6V1E2,GALNT13,SATB1,DDIT4,OTUD1,CA2,FAM107B,EBF4,BARX1,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,PARD3B,EDEM3,DUSP9,WWC1,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,IL15,PLEKHA5,MORC4,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,GULP1,MDH1B,WWC2,POU2F2,MET,HSPA2,SUSD3,DPP10,FER,PHLDB2,SLC39A8,TES,TTLL7,DOCK5,C1orf174,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,REL,LRP4,NSUN6,CLSTN2,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,DHRS12,IQGAP3,TNFRSF11A,RIN2,MSX1,ESRRG,CYTH3,GRID1,OGDHL,PRRG1,MEI1,MARS,AGAP2,PHACTR2,ARHGAP32,ZFPM2,C3orf70,MAP1B,RERE,GPR37,ADAMTS17,MYADM,NACC2,MPP7,PRCP,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SNPH |
| 1.260e-09 | -20.49 | RTAAACA_V$FREAC2_01 | MSigDB lists | RTAAACA_V$FREAC2_01 | 856 | 139 | 17377 | 1707 |
PHACTR3,TRIM2,ACSL1,TCP11L2,GRIK2,VAMP8,NDRG2,DOCK3,IKZF2,HMCN1,TRPS1,PLS3,GRHL1,ABI3BP,SLC10A7,PPP2R2B,ETV1,POU3F3,NKX2-1,GPM6A,GCNT2,SMAD9,PNRC1,ACVR1C,ANK2,JPH1,SLC25A28,ROR1,EML1,TRIM9,KLF12,ADRB1,SPRY4,PPARGC1A,LPP,PCSK5,BCL11B,UST,GPR63,LONRF1,CHCHD7,DYNC1I1,FOXG1,TNFRSF19,DDIT4,MECOM,EFEMP1,IGF1R,FRY,RALGPS2,CACNB2,FLRT3,MYC,SAMD11,GFRA1,NDUFA4L2,BDNF,RHOQ,SLITRK2,MGAT4B,FHL2,SLITRK5,PRDM1,SNAP25,MBNL2,CLN5,NAP1L5,PLEKHH2,PELI2,MATN2,SCAMP1,PLXNA2,NTRK3,KCTD12,GRK6,LCP2,COLEC10,ZFYVE9,ZNF362,KCTD15,ZNF521,SCRN1,DAB2IP,PJA1,MARCKS,MYT1,CTH,DPP10,PANK1,FGF12,SATB2,DOCK5,ISG20,BCL11A,ZNF711,MSC,PDLIM3,BACH2,MBOAT2,HOXB9,MAPK10,LIFR,MID1,RAB30,PCDH18,IGFBP6,C1QTNF3,CLGN,PLAG1,BIK,RASD1,SLC12A6,CREB5,ZNF219,PPP2R3A,NEDD4,NEO1,ATXN7L1,FOXP2,KLF9,ZFP36L2,DUSP1,MN1,ESRRG,NR4A1,FOXN3,NPDC1,SKAP1,HOXA1,GALNT3,MAP2K6,GNAO1,MCC,KIF21A,BMP4,SHOX2,MMP16,PKIA,OCLN |
| 1.384e-09 | -20.40 | PDZ | interpro domains | IPR001478 | 147 | 40 | 18492 | 1811 |
FRMPD3,ARHGEF11,RHPN2,TJP1,APBA1,RADIL,PPP1R9A,PCLO,TIAM2,SIPA1L2,PDZD8,PDZD7,CNKSR3,LIN7A,GRIP1,MPDZ,MAST4,RIMS2,INTU,PDLIM7,SYNPO2,PTPN13,MPP1,RAPGEF2,PARD3B,SHANK2,DEPTOR,PREX1,SYNJ2BP,SNTB1,MAGI3,ARHGAP21,PDLIM3,MPP7,MPP2,AHNAK2,DLG2,APBA2,MAGI2,MAST1 |
| 1.396e-09 | -20.39 | regulation of multicellular organismal process | biological process | GO:0051239 | 2993 | 378 | 17256 | 1658 |
ACVR1,LGR4,LDLR,VAMP8,GATA3,STAT5B,CEBPA,PRKCA,RAC3,STK24,NCS1,NOS1AP,TRPS1,SKI,TYMP,FBXO32,TGFBR3,RAP2A,PACSIN1,NKX2-1,MEIS2,ACVR1C,DCC,LRRK2,FEZ1,AGO4,KCND3,ACVR2B,F12,SAV1,GPC6,ENPP1,NCKAP1L,CCBE1,PLK2,ADRB1,BMP1,ZBTB20,SEMA3C,MAPK13,SERPINI1,INPP5F,TPM1,NRP1,SPART,VASH2,MEF2C,EFNB2,SCN5A,LATS2,CELSR1,PTPRD,ZHX3,CYP2J2,GTF2IRD1,FOXG1,IL17D,MCOLN2,CHN1,CNTN4,APLF,CACNB2,MYC,FLRT3,PRELID1,SREBF1,PRKG1,GRIP1,TOX,TSPAN12,CHRM3,RIMS2,GPR161,HMGCR,EPB41L5,PTCH2,ENAM,BDNF,DISC1,PNP,VLDLR,RYR2,NSD2,SMARCD3,CALCRL,PLS1,SNAP25,PLCB1,THBS4,SFMBT1,LAPTM4B,HOXD13,TRPC3,CDH2,SHTN1,EPHA3,MTG1,NBL1,DNM3,AMOTL1,PLXNA2,PKP2,CHUK,NRXN1,TLR3,DACT1,DAB2IP,PDE4D,ZNF365,KCNB2,FZD1,SSH3,GAPDH,ADM2,FZD4,NKX3-2,SHANK2,PREX1,NLGN4X,PRKCQ,WNT11,ATP1B1,ATOH1,DSP,ASPH,FGFR1,SNCA,GJC1,CXCL10,IKZF3,PRKCB,APELA,WWTR1,BMPR1A,ATG5,COBL,WASF3,C1QTNF3,ROBO2,PLAG1,CD276,HERC5,GAS6,P2RY1,EPHB1,ZNF219,GDPD5,PHLDA2,NEDD4,ADGRB2,IRX5,LRRN1,GHR,FIG4,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,ZFP36L2,FES,TRPM4,PDLIM7,VEGFC,LZTS3,GSTM2,RAPGEF2,RACK1,HEG1,GPLD1,CEBPB,ID3,FGR,TERT,AKT3,GNAO1,XBP1,MCC,GRIN2D,BMP4,SHOX2,DDIT3,ATP2B4,FOXA1,ATP1A3,TLL2,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,LILRB1,ITPR2,ABAT,CACNB4,KREMEN1,F3,RND2,EOMES,KCNN2,GRHL1,ITGB3,TRPC1,CTTN,ENO1,TLR4,IL1RAP,SLIT2,PDGFRB,RASGRP1,PRKACB,CYP1B1,DBN1,KCNIP3,ATF4,GCNT2,COL4A3,CEMIP2,ANK2,YAP1,ROR1,KCNMB4,GPRC5B,HPSE,MAP2,TNFRSF1A,OXTR,DLX2,PPARGC1A,TNFSF4,MAGI2,MLLT3,BCL11B,UST,RUNX2,FN1,LGALS3,BVES,UBASH3B,CHADL,CHSY1,PFN2,SPINK5,IL18R1,EFEMP1,NUMBL,CA2,SEMA4F,GATA2,HS3ST5,LRP6,ADCY6,INAVA,NOS3,PAK1,SLITRK2,MSTN,BTNL9,EFNA3,WWC1,MAFB,SLITRK5,PRDM1,SDK1,BAIAP2,NEGR1,MAPKAPK2,KCNK15,ADGRB3,CSF1,HEYL,HK2,SEMA3A,TESC,SIX2,SFN,PRKN,ID1,ZSWIM5,DOCK1,IL15,CELSR3,RBFOX2,HECW2,NTRK3,PIBF1,PPP1R9A,CBLN1,SEMA6A,SCIN,UNC13B,BCL6,ADGRL1,ACVR2A,PROS1,WWC2,MET,ZNF488,SNAI2,GLI1,CTH,INTU,PHLDB2,EVL,CSN2,TMEM65,NOP53,PTPN6,FGF12,RNF125,VIM,GSTO1,SYNJ2BP,AMIGO1,CD40,DOCK5,WARS,SMAD3,NRG3,GBP1,PTK7,ITGA2,PTPRS,HGF,HEY1,CNTN1,TNIK,BMPR2,REL,APBB1,LRP4,NLRP14,CLSTN2,IGF2BP2,OVOL2,CUEDC2,BMP6,ARHGAP44,NKX6-1,RAB11FIP5,FOXP2,KCNJ4,SCN1B,PRKCD,STC2,EHD3,DSG2,KIAA0319,TFAP2A,SGK1,PRICKLE2,AFAP1L2,SH3PXD2B,IQGAP3,TNFRSF11A,TESPA1,SYK,SLC45A3,ATP2B1,MSX1,KDM5B,LITAF,PRICKLE1,ZFPM2,TLR6,LEPR,MAP1B,DKK1,DDAH1,DOCK7,MYADM,FAT4,FBN1,PRCP,CTSV,MYRF,PAX9,CACNA2D1 |
| 1.539e-09 | -20.29 | RAF_UP.V1_DN | MSigDB lists | RAF_UP.V1_DN | 183 | 46 | 17377 | 1707 |
EFNB2,WASF3,COL9A3,MXI1,ID1,SIDT1,UGDH,MYO1B,ENAH,SLC7A2,ABAT,SLC19A2,TBC1D30,DDIT4,TRPS1,BAG3,PPM1E,ABLIM1,IGF1R,PMAIP1,GHR,STC2,TFAP2A,MPDZ,GULP1,CPE,GFRA1,RASGRP1,PCSK6,VAV3,GDAP1,MYO10,SLC39A8,MAFB,AK4,PLS1,SATB2,PALLD,PLCB1,TBC1D16,DKK1,RND3,PLK2,INPP4B,INPP5F,TTC39A |
| 1.551e-09 | -20.28 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | 432 | 83 | 17377 | 1707 |
GXYLT2,IL15,PRSS12,RGS20,KCTD12,SPATS2L,PRKCA,EYA4,CPNE2,GULP1,PROS1,MET,KLHL29,SLIT2,SNAI2,PHLDB2,FER,ANTXR2,COL6A2,ABCC4,SMAD9,RNF145,WLS,MSRB3,VIM,ATP10D,CENPV,GNAI1,DCBLD2,SMAD3,ARHGAP21,GPRC5B,POPDC3,CCBE1,LAMB1,WWTR1,AHNAK2,NRP1,TPM1,MID1,GNG12,RUNX2,MRC2,IGFBP6,ITPRIP,TBC1D1,ZCCHC24,UBASH3B,IPO5,ZIC2,IGF2BP2,CHSY1,INPP1,FHOD3,NAV1,BCHE,SGK1,ACTA2,TOX,PRR16,SPRY2,FMNL2,GPR161,PNMA2,SNX7,GPR176,BDNF,CRIM1,MPP1,STRADB,MAP1B,HEG1,NAP1L5,FAT4,FBN1,AKT3,EMILIN2,RAB31,RAI14,LRRK1,SHOX2,SEMA3A,CSRP2 |
| 1.667e-09 | -20.21 | PH_domain | interpro domains | IPR001849 | 267 | 59 | 18492 | 1811 |
ARHGAP26,FARP1,DNM3,RASAL2,ARHGEF11,GRB14,PLEKHA5,ARHGAP22,OPHN1,PSD3,PHLDA2,DOK5,TIAM2,RALGPS2,MCF2L,AFAP1L2,DAB2IP,RTKN2,CADPS2,IPCEF1,GAB2,PHLDB2,VAV3,ARAP2,SH3BP2,ARHGEF28,SKAP2,MYO10,PLEKHA8,MCF2L2,CYTH3,ASAP3,PREX1,SPATA13,RASA3,OBSCN,FERMT2,AGAP2,CDC42BPA,PLEKHA1,SNTB1,SKAP1,GRK3,PLEKHB1,ARHGEF26,TBC1D2,IRS2,ARHGAP21,PLEKHH2,AKT3,RASGRF2,OSBPL5,PLEKHG1,GRB10,PLD1,IQSEC2,OSBPL6,KIF1B,DOCK9 |
| 1.733e-09 | -20.17 | TTANTCA_UNKNOWN | MSigDB lists | TTANTCA_UNKNOWN | 876 | 141 | 17377 | 1707 |
MPZL3,ACVR1,KIF5A,UGDH,FHDC1,CEBPA,ADAMTS6,CA8,IKZF2,PCDH7,TRPS1,PLS3,LGI2,RTN1,CPVL,ABI3BP,ATRNL1,JAKMIP2,BEND4,PPP2R2B,DBN1,GPM6A,MEIS2,SESN2,GCNT2,COL4A3,ROR1,NT5DC2,GNAI1,GPR150,TCF7L1,MAP2,B3GALT2,TMEFF2,TNFSF4,TYRO3,ITPRIP,ZIC2,PFN2,RNF141,EFEMP1,NUMBL,ABLIM1,BNIP1,IGF1R,SLC7A11,PDZD7,BACE2,FLRT3,ZIC5,VGLL4,TSPAN9,GFRA1,PAK1,MSTN,MYO10,COL4A4,VLDLR,HOMER2,RYR2,STRADB,PRDM1,BAIAP2,MAPKAPK2,TEX15,MFSD2A,SEMA3A,PANK3,SFN,MYO1B,IL13RA1,COLEC10,PRR7,SP8,KCTD15,FABP6,MYO3B,RTKN2,PDE4D,PJA1,MET,SCN2A,DNAH5,HRASLS,SHANK2,FGF12,WNT11,ATP10D,METAP1D,FGFR1,SMAD3,PTK7,KLF5,HGF,LIFR,NR3C2,CTNND2,IGFBP6,BMPR2,KLHL13,CMTM8,PRDM8,COL4A5,CREB5,SFXN3,NEDD4,NEO1,ATXN7L1,FOXP2,RAB11FIP5,TECPR1,CHN2,LRRN1,EIF1,TSC22D1,ERRFI1,C15orf41,FES,RBMS2,DUSP1,ARAP2,USP2,CRIM1,ESRRG,PRICKLE1,ZFPM2,EXOG,UCHL3,ILDR2,HOXA1,NAALADL2,HOMER3,CEBPB,DOCK7,DLG2,SH3BGRL2,ZNF474,BMP4,PAX9,KIF1B,PKIA |
| 1.827e-09 | -20.12 | neoplasm | COSMIC cancer mutations | neoplasm | 15237 | 1561 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,SLC19A2,TLR3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,SLC39A14,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,IGFBP3,RPS13,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,HEY1,TENM1,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,DOCK3,NHP2,CA8,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,FMNL2,LRP12,CHRM3,RPS23,HMGCR,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,WWTR1,INPP4B,PLEKHG1,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,FARP1,TMEM132C,C1QTNF3,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,LPCAT2,XYLT1,OR51B4,ZNF83,LPIN3,SEZ6L2,CBLN1,PCLO,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,ZNF827,TMEM53,STARD4,SCRN1,NBEA,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,RGS7,GDPD5,NEDD4,RGS17,SOAT2,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,FAM27C,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,BARX1,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.843e-09 | -20.11 | lung-right_upper_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-right_upper_lobe-carcinoma-adenocarcinoma | 10661 | 1153 | 17385 | 1698 |
ARHGAP26,THOC5,ADAL,GRIK2,RECK,TUBE1,NPM1,BCAN,KIAA1217,SNX9,SKI,IKZF5,RAP2A,TMED9,PPP2R2B,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,ERCC5,INPP5F,CAB39L,DNHD1,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,ARID5B,EFHC2,FASN,HIP1,AIG1,ST6GALNAC3,ZBBX,CLN5,SPATA7,CACHD1,TEX15,GSTO2,RPL28,CDH2,DOCK9,MTG1,ABHD13,ADD2,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,NECAB1,PFKFB2,ADCY1,DSP,ASPH,ZNF618,MAGI3,SLC39A14,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,RAB30,CCDC148,WDR17,CKAP2,GCAT,FZD8,ESRP1,BACE1,PLAG1,UBAC2,SLC12A6,EPHB1,BEX2,HMGCS1,LRRN1,GHR,C15orf41,MED12L,TRPM4,PDLIM7,MN1,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,RAPGEF5,PGBD5,ZNF391,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,CRYBG3,SPNS1,DYRK1B,TRIM9,KLF12,ERN1,AHNAK2,HS6ST3,RRAGD,LONRF1,STXBP5L,SORBS3,ZNF215,DOK5,FHOD3,RNF180,ZBTB38,ZNF440,FRAS1,HS3ST5,GAN,SMTN,LRP6,MED7,FAR2,VGLL4,DPYSL5,GPSM1,OBSCN,SLITRK5,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,DDX60L,ZNF362,TACC2,BCL6,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,INTU,CSN2,TDRD3,PRDM13,ACO1,CHRNA6,VIM,PTPRJ,PTPRS,MAOA,HGF,MBOAT2,CTNND2,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,SLC35F1,FOXP2,TFAP2A,SGK1,TSPAN13,SYK,ATP2B1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,EBF1,DOCK7,FBN1,SH3BGRL2,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,TRPS1,ZFYVE28,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,FAM84A,EFHC1,ZDHHC14,GNAI1,ENPP6,BMP1,MAPK13,SERPINI1,DSEL,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,CPXM2,GRIP1,FAM155A,PRR16,COL9A2,GPR161,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,CECR2,THBS4,LRRIQ3,MATN2,MPP2,DYNC2LI1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,POU5F1B,ALDOC,SHF,GAB2,TRDMT1,SHANK2,PREX1,NLGN4X,SATB2,ATOH1,PYGO1,ATP1B1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,CCNA1,ZNF704,HPGD,BMPR1A,COBL,PURG,STON2,MID1,HACE1,MYO1D,PLSCR4,EPS8,HERC5,KIF5C,RASSF8,LRRC55,AFF2,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,VAV3,SLC40A1,ARHGEF28,SH3BP2,AGPAT4,PTPN13,ZDHHC15,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,LARP1,ACSL1,UGT8,ACTL8,C20orf194,HMCN1,ADPRHL1,LGI2,SIPA1L2,ABI3BP,ANKFN1,CNNM2,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,RHOBTB1,BVES,FBXO4,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,CEBPD,CAND2,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,STEAP1,HERPUD1,CSAG1,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PDZD8,CDC14B,PPFIBP1,REEP1,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,BCL11A,ARMC4,CAMK2N1,MAGEA12,ZNF93,KPNA3,RBPMS2,TMPRSS9,RNF130,MAST1,ARHGEF11,SSX1,COL4A5,IGF2BP2,FAM117B,SEL1L3,BMP6,SYDE2,MCU,RAB11FIP5,FSD1,KCNJ4,PRKCD,STC2,AFAP1L2,IPCEF1,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,PRSS12,AASS,DNAJC3,CADM2,DOCK3,NHP2,NOS1AP,EYA4,PCDH7,BAG3,TGFBR3,DNAH6,FAAH2,PPFIA2,TSHR,NKX2-1,MEIS2,SMAD9,GJB2,CAP2,MSRB3,F12,MFSD6,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CARS,LATS2,STOX2,CYP2J2,SLC36A4,SYCP2,BNIP1,CACNB2,ZIC5,PRELID2,ST8SIA1,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,CHRM3,LRP12,HMGCR,FADS1,BDNF,PNP,MYO10,STAT4,CALCRL,SMARCD3,RYR2,C1R,OR11H4,TAF4B,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,GALNT6,C4A,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,JAKMIP3,RAB27B,ARL4D,FAM155B,SCN3A,DOCK8,DZANK1,SSH3,RNF145,FZD4,KCNH5,NKX3-2,RAB38,FGFR1,METAP1D,IRS2,IQCH,GYPC,PEMT,INPP4B,PLEKHG1,PAM,TNFSF15,PLD5,HOXB9,SERINC5,FARP1,EDA2R,ROBO2,C1QTNF3,IPO5,C1orf226,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,NPTXR,MYO6,ULBP1,CLYBL,RAPGEF2,MCF2L2,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,FOXA1,DCBLD1,TRIM2,FHDC1,LILRB1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,KIAA1614,TLN2,TLR4,NEB,ABCC4,TCERG1L,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,CCDC146,TECPR2,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,RASL11B,SETBP1,MLC1,PGAP1,IL18R1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,SEMA4F,IGF1R,ABCA5,GATA2,BCHE,PDE10A,SAMD11,BNIP3,FBXL2,PAK1,CHSY3,UNC5C,MID2,SPATA13,TMTC4,PPFIA4,WDR25,MFSD2A,PANK3,SFN,SIX2,MME,CFH,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CBLN1,FAM131B,TBC1D19,LHX6,MYO3B,SCN2A,CLVS2,GLI1,TMEM67,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,KCNG1,ABI3,ITGA2,TTC39A,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,GABRG2,HBE1,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,SH3PXD2B,SLC45A3,KIAA1211,DLGAP1,MICAL2,NUAK2,FNDC3A,FAT4,ZNF214,DLG2,RPL4,PAX9,TBC1D4,FILIP1,MYCBP2,PAGE1,ACVR1,PPP4R4,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,NCS1,CFHR1,SLC16A2,CHRDL1,ATRNL1,VWA5A,PACSIN1,MAGEA6,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,TNS1,SLC25A28,ACVR2B,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,RASGRF2,ENTPD7,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,EHHADH,CELSR1,ZHX3,PTPRD,GABRB2,SCN8A,OLAH,OPHN1,GTF2IRD1,SLC1A3,DYNC1I1,ADSSL1,RPL13A,MCOLN2,NAV1,CNTN4,PIK3AP1,PDZD7,RUNDC3B,SLC16A9,MPDZ,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,IQSEC2,AMPD1,ACSM3,PLA2G4A,EPHA3,AMOTL1,PCSK1N,RASAL2,ELOVL4,GPR65,ZNF311,OTX1,CHUK,NUDT12,ZNF827,NELL2,NBEA,SCRN1,DAB2IP,NAP1L3,MARCKS,ATP6AP1L,VNN2,SOX21,PRKCQ,TBC1D16,HTR7,PRKCB,KLF5,GRB10,ATG5,CTTNBP2,KCTD1,DENND5B,WASF3,ANKRD13D,ATP9A,CCNJL,GPR180,GABRR2,RGS7,NEDD4,MGAT1,RALGAPA2,SLC6A15,FIG4,SEPT3,SPRY2,SMPDL3A,ARAP2,SYNPO2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,PGM2L1,MYOM2,GRIN2D,NUDT17,ATP1A3,SLC43A1,EXPH5,MPZL3,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,CACNB4,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,ARHGEF10L,RTN1,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,OR2W3,FANK1,SLIT2,PRKACB,RASGRP1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,APBA2,BCL11B,UST,FN1,SEC24D,RIMKLA,YPEL2,LAMC3,GALNT13,SATB1,PHGDH,FAM107B,NCEH1,NOS3,GPR176,SH2D2A,PARD3B,EDEM3,DUSP9,WWC1,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,IL15,PLEKHA5,MORC4,TDRKH,BCL6B,DOCK2,SP8,COL22A1,KCTD15,SETDB2,RPS6KL1,ZNF521,MAP7,MDH1B,POU2F2,MET,ZNF460,HSPA2,SUSD3,GCA,FER,PHLDB2,SLC39A8,TES,SYNJ2BP,DOCK5,TTLL7,WARS,TPK1,MSC,LMLN,BACH2,SOHLH2,DISP1,LIFR,OR51B5,TNIK,REL,LRP4,NSUN6,CLSTN2,CUEDC2,NKX6-1,CHN2,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,FKBP14,TNFRSF11A,RIN2,RAB3B,ESRRG,NR4A1,CYTH3,GRID1,OGDHL,MEI1,MARS,PHACTR2,AGAP2,ARHGAP32,ZFPM2,C3orf70,RERE,MAP1B,GPR37,ADAMTS17,MYADM,MAP2K6,PRCP,THSD7B,KIF21A,GEM,MAP3K20,MMP16,SLC16A10,STOM |
| 1.843e-09 | -20.11 | right_upper_lobe | COSMIC cancer mutations | right_upper_lobe | 10661 | 1153 | 17385 | 1698 |
ARHGAP26,THOC5,ADAL,GRIK2,RECK,TUBE1,NPM1,BCAN,KIAA1217,SNX9,SKI,IKZF5,RAP2A,TMED9,PPP2R2B,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,ERCC5,INPP5F,CAB39L,DNHD1,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,ARID5B,EFHC2,FASN,HIP1,AIG1,ST6GALNAC3,ZBBX,CLN5,SPATA7,CACHD1,TEX15,GSTO2,RPL28,CDH2,DOCK9,MTG1,ABHD13,ADD2,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,NECAB1,PFKFB2,ADCY1,DSP,ASPH,ZNF618,MAGI3,SLC39A14,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,RAB30,CCDC148,WDR17,CKAP2,GCAT,FZD8,ESRP1,BACE1,PLAG1,UBAC2,SLC12A6,EPHB1,BEX2,HMGCS1,LRRN1,GHR,C15orf41,MED12L,TRPM4,PDLIM7,MN1,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,RAPGEF5,PGBD5,ZNF391,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,CRYBG3,SPNS1,DYRK1B,TRIM9,KLF12,ERN1,AHNAK2,HS6ST3,RRAGD,LONRF1,STXBP5L,SORBS3,ZNF215,DOK5,FHOD3,RNF180,ZBTB38,ZNF440,FRAS1,HS3ST5,GAN,SMTN,LRP6,MED7,FAR2,VGLL4,DPYSL5,GPSM1,OBSCN,SLITRK5,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,DDX60L,ZNF362,TACC2,BCL6,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,INTU,CSN2,TDRD3,PRDM13,ACO1,CHRNA6,VIM,PTPRJ,PTPRS,MAOA,HGF,MBOAT2,CTNND2,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,SLC35F1,FOXP2,TFAP2A,SGK1,TSPAN13,SYK,ATP2B1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,EBF1,DOCK7,FBN1,SH3BGRL2,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,TRPS1,ZFYVE28,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,FAM84A,EFHC1,ZDHHC14,GNAI1,ENPP6,BMP1,MAPK13,SERPINI1,DSEL,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,CPXM2,GRIP1,FAM155A,PRR16,COL9A2,GPR161,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,CECR2,THBS4,LRRIQ3,MATN2,MPP2,DYNC2LI1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,POU5F1B,ALDOC,SHF,GAB2,TRDMT1,SHANK2,PREX1,NLGN4X,SATB2,ATOH1,PYGO1,ATP1B1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,CCNA1,ZNF704,HPGD,BMPR1A,COBL,PURG,STON2,MID1,HACE1,MYO1D,PLSCR4,EPS8,HERC5,KIF5C,RASSF8,LRRC55,AFF2,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,VAV3,SLC40A1,ARHGEF28,SH3BP2,AGPAT4,PTPN13,ZDHHC15,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,LARP1,ACSL1,UGT8,ACTL8,C20orf194,HMCN1,ADPRHL1,LGI2,SIPA1L2,ABI3BP,ANKFN1,CNNM2,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,RHOBTB1,BVES,FBXO4,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,CEBPD,CAND2,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,STEAP1,HERPUD1,CSAG1,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PDZD8,CDC14B,PPFIBP1,REEP1,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,BCL11A,ARMC4,CAMK2N1,MAGEA12,ZNF93,KPNA3,RBPMS2,TMPRSS9,RNF130,MAST1,ARHGEF11,SSX1,COL4A5,IGF2BP2,FAM117B,SEL1L3,BMP6,SYDE2,MCU,RAB11FIP5,FSD1,KCNJ4,PRKCD,STC2,AFAP1L2,IPCEF1,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,PRSS12,AASS,DNAJC3,CADM2,DOCK3,NHP2,NOS1AP,EYA4,PCDH7,BAG3,TGFBR3,DNAH6,FAAH2,PPFIA2,TSHR,NKX2-1,MEIS2,SMAD9,GJB2,CAP2,MSRB3,F12,MFSD6,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CARS,LATS2,STOX2,CYP2J2,SLC36A4,SYCP2,BNIP1,CACNB2,ZIC5,PRELID2,ST8SIA1,NCAM1,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,CHRM3,LRP12,HMGCR,FADS1,BDNF,PNP,MYO10,STAT4,CALCRL,SMARCD3,RYR2,C1R,OR11H4,TAF4B,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,GALNT6,C4A,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,JAKMIP3,RAB27B,ARL4D,FAM155B,SCN3A,DOCK8,DZANK1,SSH3,RNF145,FZD4,KCNH5,NKX3-2,RAB38,FGFR1,METAP1D,IRS2,IQCH,GYPC,PEMT,INPP4B,PLEKHG1,PAM,TNFSF15,PLD5,HOXB9,SERINC5,FARP1,EDA2R,ROBO2,C1QTNF3,IPO5,C1orf226,NKAIN2,CREB5,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,NPTXR,MYO6,ULBP1,CLYBL,RAPGEF2,MCF2L2,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,FOXA1,DCBLD1,TRIM2,FHDC1,LILRB1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,KIAA1614,TLN2,TLR4,NEB,ABCC4,TCERG1L,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,CCDC146,TECPR2,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,RASL11B,SETBP1,MLC1,PGAP1,IL18R1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,SEMA4F,IGF1R,ABCA5,GATA2,BCHE,PDE10A,SAMD11,BNIP3,FBXL2,PAK1,CHSY3,UNC5C,MID2,SPATA13,TMTC4,PPFIA4,WDR25,MFSD2A,PANK3,SFN,SIX2,MME,CFH,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CBLN1,FAM131B,TBC1D19,LHX6,MYO3B,SCN2A,CLVS2,GLI1,TMEM67,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,KCNG1,ABI3,ITGA2,TTC39A,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,GABRG2,HBE1,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,SH3PXD2B,SLC45A3,KIAA1211,DLGAP1,MICAL2,NUAK2,FNDC3A,FAT4,ZNF214,DLG2,RPL4,PAX9,TBC1D4,FILIP1,MYCBP2,PAGE1,ACVR1,PPP4R4,TTC39B,SIDT1,TCP11L2,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,NCS1,CFHR1,SLC16A2,CHRDL1,ATRNL1,VWA5A,PACSIN1,MAGEA6,PLTP,TBC1D8,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,TNS1,SLC25A28,ACVR2B,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,RASGRF2,ENTPD7,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,EHHADH,CELSR1,ZHX3,PTPRD,GABRB2,SCN8A,OLAH,OPHN1,GTF2IRD1,SLC1A3,DYNC1I1,ADSSL1,RPL13A,MCOLN2,NAV1,CNTN4,PIK3AP1,PDZD7,RUNDC3B,SLC16A9,MPDZ,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,IQSEC2,AMPD1,ACSM3,PLA2G4A,EPHA3,AMOTL1,PCSK1N,RASAL2,ELOVL4,GPR65,ZNF311,OTX1,CHUK,NUDT12,ZNF827,NELL2,NBEA,SCRN1,DAB2IP,NAP1L3,MARCKS,ATP6AP1L,VNN2,SOX21,PRKCQ,TBC1D16,HTR7,PRKCB,KLF5,GRB10,ATG5,CTTNBP2,KCTD1,DENND5B,WASF3,ANKRD13D,ATP9A,CCNJL,GPR180,GABRR2,RGS7,NEDD4,MGAT1,RALGAPA2,SLC6A15,FIG4,SEPT3,SPRY2,SMPDL3A,ARAP2,SYNPO2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,PGM2L1,MYOM2,GRIN2D,NUDT17,ATP1A3,SLC43A1,EXPH5,MPZL3,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,CACNB4,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,ARHGEF10L,RTN1,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,OR2W3,FANK1,SLIT2,PRKACB,RASGRP1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,NCAM2,ITGBL1,NCOA7,APBA2,BCL11B,UST,FN1,SEC24D,RIMKLA,YPEL2,LAMC3,GALNT13,SATB1,PHGDH,FAM107B,NCEH1,NOS3,GPR176,SH2D2A,PARD3B,EDEM3,DUSP9,WWC1,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,IL15,PLEKHA5,MORC4,TDRKH,BCL6B,DOCK2,SP8,COL22A1,KCTD15,SETDB2,RPS6KL1,ZNF521,MAP7,MDH1B,POU2F2,MET,ZNF460,HSPA2,SUSD3,GCA,FER,PHLDB2,SLC39A8,TES,SYNJ2BP,DOCK5,TTLL7,WARS,TPK1,MSC,LMLN,BACH2,SOHLH2,DISP1,LIFR,OR51B5,TNIK,REL,LRP4,NSUN6,CLSTN2,CUEDC2,NKX6-1,CHN2,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,FKBP14,TNFRSF11A,RIN2,RAB3B,ESRRG,NR4A1,CYTH3,GRID1,OGDHL,MEI1,MARS,PHACTR2,AGAP2,ARHGAP32,ZFPM2,C3orf70,RERE,MAP1B,GPR37,ADAMTS17,MYADM,MAP2K6,PRCP,THSD7B,KIF21A,GEM,MAP3K20,MMP16,SLC16A10,STOM |
| 1.846e-09 | -20.11 | ovary-carcinoma-serous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-serous_carcinoma | 11013 | 1186 | 17385 | 1698 |
ARHGAP26,THOC5,GRIK2,CNTNAP3,RECK,TUBE1,ALG1L,CTBP2,BCAN,KIAA1217,ABHD6,SKI,RAP2A,PPP2R2B,TMEM37,CPE,POU3F3,DCC,DSTN,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,ENPP1,WIPF3,ATP7B,MAP9,ERCC5,DIRAS1,INPP5F,TMOD2,DNHD1,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,FOXG1,BBS9,CHN1,FRY,APLF,FLRT3,SRGAP1,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,CLN5,SPATA7,CACHD1,TEX15,GSTO2,CLMN,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,DNAH5,ZNF365,MYT1,ANKRD18B,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,ENTPD1,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,CCDC148,ANKRD13B,WDR17,CKAP2,CD276,BACE1,BIK,UBAC2,PSD3,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,GHR,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,MN1,AK4,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,NEK11,BMP4,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,TMEM86A,ITGB3,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,MARK1,KCNIP3,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,SESN1,DYRK1B,TRIM9,TCF7L1,KLF12,ERN1,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,ZNF215,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,STRADB,SLITRK5,OBSCN,SDK1,KHDRBS2,GPR19,NEGR1,TBC1D2,GRIK4,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,PPP1R9A,SEMA6A,DDX60L,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,INTU,CSN2,LRRC8B,TDRD3,ACO1,CHRNA6,VIM,IFT81,PTPRJ,PTPRS,MAOA,HGF,SUSD4,CTNND2,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,FOXP2,TTC1,KCNMB3,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,TRPS1,TYMP,ZFYVE28,SERINC2,KCNS3,THSD1,GLDC,ERGIC1,ACVR1C,KLHL3,LRMP,EFHC1,ZDHHC14,BMP1,MAPK13,DSEL,SPRY4,NRP1,SPOCK3,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,LRRC49,APBA1,MTUS1,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,CPXM2,GRIP1,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,CECR2,THBS4,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,NBL1,TCTN2,ST14,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,SHANK2,PREX1,NLGN4X,SATB2,CBY1,PYGO1,ATP1B1,ATP10D,C9orf116,SNCA,ZNF711,IKZF3,POPDC3,CCNA1,BMPR1A,COBL,PURG,MID1,HACE1,MYO1D,IGFBP6,EPS8,PRSS35,HERC5,NDFIP2,INPP1,RASSF8,LRRC55,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,TMC7,VAV3,SLC40A1,ALDH2,SH3BP2,PXN,AGPAT4,PTPN13,TMEM126A,ZDHHC15,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,LARP1,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,PPM1E,SIPA1L2,ABI3BP,ANKFN1,CNNM2,TRPC1,CTTN,MYRIP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,SGK2,GSN,GPRC5B,HPSE,FAM114A2,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,RHOBTB1,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,LIMCH1,RNF148,LRP3,SNX7,ZNF629,CDH26,PCDH10,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,TMEM154,CSAG1,KIAA0355,FAT1,SH3BP4,TMEM117,PTPRN2,DISP2,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,PIBF1,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,MVD,TCEAL3,AMIGO1,CD40,BCL11A,ARMC4,KPNA3,TRIM34,TMPRSS9,EIF4EBP1,DUSP19,RNF130,MAST1,ENO2,ARHGEF11,ARL15,TNFSF13B,COL4A5,FAM117B,OVOL2,BMP6,SYDE2,RAB11FIP5,FSD1,KCNJ4,SCN1B,PRKCD,STC2,MARCH3,AFAP1L2,IPCEF1,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,LEPR,CTIF,DPY19L2,MFSD9,EDA,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,FAM102B,CADM2,STAT5B,DOCK3,NHP2,EYA4,EPDR1,PCDH7,BAG3,TGFBR3,DNAH6,FAAH2,PPFIA2,KLHL29,TSHR,MEIS2,WLS,CAP2,MFSD6,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,LPP,CARS,LATS2,STOX2,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,ZIC5,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,PNP,MYO10,STAT4,RYR2,CALCRL,SMARCD3,OR11H4,DHX32,BEX4,TMCO3,ADAMTS3,EMILIN2,CDH17,FBXO27,TRPC3,CSRP2,ZNF516,DNM3,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,RGS20,PKP2,NRXN1,LCP2,COLEC10,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,PJA1,FAM155B,JAKMIP3,ARL4D,DOCK8,SCN3A,PERP,SSH3,GARS,RNF145,FZD4,KCNH5,FGFR1,IQCK,IQCH,ZNF697,GPR160,WWTR1,INPP4B,PLEKHG1,RCN3,ALG11,P4HA1,PLD5,KLHL31,SERINC5,FARP1,ROBO2,IPO5,C1orf226,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,GAS2L3,MYO6,FES,BCL7A,RAPGEF2,MCF2L2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,AKT3,SLCO5A1,HK1,DOCK6,BTRC,DCBLD1,TRIM2,SYT12,FHDC1,LILRB1,ASS1,SYT14,NOVA1,FSTL5,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,LIN7A,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,SLC3A2,ABCC4,PLEKHA1,TCERG1L,BATF,PLEKHB1,MAP2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,UBASH3B,RASL11B,SETBP1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,PDE10A,SAMD11,SLCO4C1,PAK1,CHSY3,FGFR4,UNC5C,MID2,SLC27A2,SPATA13,TMTC4,PPFIA4,PDE8A,MAPKAPK2,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,AVPI1,CFH,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,LPIN3,SEZ6L2,PCLO,CBLN1,CYP26A1,FAM131B,TBC1D19,SLC22A17,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,TMEM67,UROS,THSD4,FGF12,FBXO36,FRK,JAM3,C4BPB,RANBP2,NRG3,GBP1,PTK7,KCNG1,ITGA2,ZNF701,CNTN1,MAN2B2,PCDH18,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SFXN3,PPP2R3A,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,NUAK2,FNDC3A,MKX,FAT4,L3MBTL4,FMO4,DLG2,PAX9,THAP10,TBC1D4,CGN,MYCBP2,ACVR1,PPP4R4,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,STK24,NCS1,MOK,SLC22A18,CFHR1,SLC16A2,CHRDL1,ATRNL1,SP140,RCAN3,VWA5A,PLTP,TBC1D8,DCDC1,NR6A1,KLHL4,DNAJC6,DEPTOR,TNS1,ACVR2B,ARHGEF26,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,SCN8A,OPHN1,GTF2IRD1,ISYNA1,SLC1A3,ADSSL1,DYNC1I1,CHD5,MECOM,MCOLN2,NAV1,CNTN4,PIK3AP1,PDZD7,RUNDC3B,OPN3,SLC16A9,TSPAN12,MPDZ,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,RASAL2,ELOVL4,RNF144A,OTX1,KCTD12,CHUK,SPATS2L,TBC1D30,ZNF827,TMEM53,NELL2,STARD4,NBEA,SCRN1,DAB2IP,NAP1L3,SERPINH1,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,KLF5,GRB10,CTTNBP2,NR3C2,KCTD1,DENND5B,WASF3,ANO10,ANKRD13D,ATP9A,GABRR2,RGS7,GDPD5,NEDD4,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,ZIC1,GPLD1,FGR,OR2T33,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,B4GALT7,NUDT17,ATP1A3,SLC43A1,EXPH5,MVK,KIF5A,UGDH,DNER,CACNB4,IKZF2,KREMEN1,SLCO3A1,CYP51A1,ARHGEF10L,RTN1,LRRC6,GRHL1,AKAP7,DLX6,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,CAPN5,ZNF565,ROR1,EML1,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,RIMKLA,ELOVL7,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,EBF4,NCEH1,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,RAI14,HK2,EGFL7,CREB3L2,CXCR5,EML5,NEK10,CELSR3,PLEKHA5,MORC4,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,STEAP3,GULP1,MDH1B,WWC2,POU2F2,MET,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,TES,DOCK5,TTLL7,C1orf174,WARS,TPK1,LMLN,BACH2,DISP1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,NKX6-1,CHN2,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,ESRRG,CYTH3,GRID1,OGDHL,PRRG1,MEI1,MARS,PHACTR2,AGAP2,ARHGAP32,ZFPM2,C3orf70,MAP1B,RERE,GPR37,ADAMTS17,MYADM,NACC2,MPP7,MAP2K6,THSD7B,KIAA0513,KIF21A,MMP16,SLC16A10,SNPH |
| 1.894e-09 | -20.08 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | 241 | 55 | 17377 | 1707 |
EPHA3,ZNF395,IGFBP6,RHOBTB1,HEBP1,MORC4,ASS1,COL18A1,ABAT,SPATS2L,PRKCA,SATB1,INPP1,COL14A1,GAS1,PCDH7,GATA2,BCHE,KCNS3,MARCH3,SGK1,JAKMIP2,MET,VWA5A,TBC1D9,PTPRE,GATM,SCN3A,SNAI2,HMGCR,FZD1,DUSP1,FGFR4,VEGFC,MN1,VAV3,COL6A2,PTPRU,ANK2,ARID5B,PHACTR2,PRKAR2B,TMEM47,HEG1,DKK1,IRS2,CAMK2N1,ID3,DDAH1,TCF7L1,CLMN,BMP4,MMP16,MME,PCSK5 |
| 1.906e-09 | -20.08 | intracellular signal transduction | biological process | GO:0035556 | 1663 | 231 | 17256 | 1658 |
FGF13,GATA3,NPM1,STAT5B,ITPR2,CHAC1,DOCK3,PRKCA,CA8,RAC3,NCS1,STK24,MOK,RND2,RPS6KA2,TGFBR3,PMAIP1,RAP2A,RAB26,RCAN3,TLR4,TSHR,RAPGEF5,RASGRP1,PDGFRB,CYP1B1,TNK2,SESN2,ATF4,MARK1,DCDC1,ANK2,LRRK2,DEPTOR,YAP1,PRKAR2B,FGF17,PLEKHA1,BATF,SGK2,SAV1,GSN,PLK2,RASGRF2,ERN1,ADRB1,TNFRSF1A,BBC3,MAPK13,PIK3C2B,INPP5F,OXTR,MEF2C,TYRO3,PRKAA2,LATS2,CELSR1,RHOBTB1,SLK,DHCR24,TJP1,GPSM2,TNFRSF19,ADGRG6,DOK5,DDIT4,CHN1,RALGPS2,IGF1R,MYC,PRKG1,INAVA,GRIP1,ADCY6,BNIP3,NCAM1,MAST4,GFRA1,RIMS2,ZNF385A,NOS3,PAK1,FGFR4,RPL26,IL17RD,RHOQ,STAT4,HOMER2,DCHS1,RAPGEF4,DUSP9,CALCRL,RYR2,STRADB,WWC1,CDC42BPA,PLCB1,MAPKAPK2,PLAGL1,PKN3,RAB31,TMEM117,PLD1,SHTN1,SFN,DOCK9,BTC,AMOTL1,RASAL2,IL15,DOCK1,RHOD,GPR65,CHUK,MAPK4,LCP2,TNKS1BP1,DOCK2,PCLO,PPP1R9A,TIAM2,TLR3,PDZD8,UNC13B,CDC14B,CNKSR3,BCL6,ADGRL1,DAB2IP,FHIT,PDE4D,MET,RAB27B,SCN2A,PERP,DOCK8,GAB2,FER,MYLK3,PDK1,ADM2,PTPN6,KCNH5,PREX1,ADCY1,GSTO1,PRKCQ,ATP1B1,RAB38,SYNJ2BP,CD40,DOCK5,FGFR1,MAGI3,PATJ,IRS2,NRG3,PRKCB,EIF4EBP1,WWTR1,MAP3K21,TNFSF15,HGF,MAPK10,RAB30,MAST1,HACE1,TNIK,EDA2R,ARHGEF11,PAK5,REL,NLRP14,EPS8,MCTP2,RASD1,GAS6,PKN1,RGS7,ADGRB2,MCU,CHN2,GPR155,MCF2L,PCBP4,BHLHA15,PRKCD,GHR,SGK3,SGK1,IPCEF1,IQGAP3,MYO6,RRAS2,SYK,ZFP36L2,DUSP1,MOB1B,TRPM4,RIN2,VAV3,ARHGEF28,RAB3B,GSTM2,RAB6B,NR4A1,RAPGEF2,NUAK2,RASA3,ARHGAP32,GUCY1A2,TLR6,CEBPB,TRIB3,DDAH1,DOCK7,TIFA,FAT4,RND3,AKT3,MAP2K6,XBP1,TUFT1,NEK11,GRIN2D,LRRK1,DOCK6,MAP3K20,BTRC,DDIT3,LARP1 |
| 1.918e-09 | -20.07 | trunk | COSMIC cancer mutations | trunk | 3628 | 451 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,CGN,THOC5,PPP4R4,LGR4,GRIK2,PRSS12,ATP8A1,LDLR,GATA3,ADAMTS6,CADM2,SNX9,CA8,EYA4,STK24,NCS1,PCDH7,TRPS1,BAG3,DNAH6,SLC16A2,PPFIA2,KCNS3,GSTM3,PPP2R2B,COG3,VWA5A,CPE,TSHR,GLDC,MEIS2,SMAD9,DCC,CAP2,GJB2,TNS1,SFXN1,SH3RF1,ENPP6,NCKAP1L,PLK2,ATP7B,RASGRF2,MAP9,BMP1,ARHGAP28,MAPK13,ERCC5,SERPINI1,NRP1,UNC5B,SPOCK3,LZTS1,LRFN5,SCN5A,TMEM63C,MRC2,INPPL1,EHHADH,CELSR1,PTPRD,ZHX3,OPHN1,LRRC49,SLC1A3,WDFY4,TNFRSF10C,APBA1,TNFRSF19,BBS9,TTC30B,GAS1,MECOM,MTUS1,SYCP2,ABLIM1,GBGT1,RALGPS2,KIAA1257,CNTN4,ADCK1,PIK3AP1,APLF,CACNB2,MYC,ZIC5,C1QL4,SRGAP1,CPXM2,TOX,LOXL4,MOXD1,STXBP1,FMNL2,LRP12,RIMS2,CHRM3,IGSF3,RNF152,PTCH2,DISC1,QSOX1,SLC36A1,COL4A4,RAPGEF4,ZNF605,RYR2,CALCRL,PLS1,SNAP25,CDC42BPA,ARRDC4,PLCB1,C4orf19,TMEM74,SPATA7,BEX4,CACHD1,TEX15,ADAMTS3,CECR2,EMILIN2,CDH17,CLMN,IQSEC2,DHCR7,AMPD1,DOCK9,PLA2G4A,EPHA3,TFCP2L1,NBL1,DNM3,ZNF516,GALNT12,GALNT6,LRRCC1,MSR1,BEGAIN,PKP2,NRXN1,COL14A1,ZFYVE9,ZNF827,CHRNA5,GPRIN1,NBEA,RAB27B,DNAH5,MYT1,GATM,KCNB2,SCN3A,DOCK8,MYLK3,GARS,COL6A2,B3GALT1,TMEM43,PFKFB2,NPM3,KCNH5,ADCY1,PRKCQ,DSP,ASPH,ATP10D,METAP1D,ZNF711,ARHGAP21,IQCH,CCNA1,INPP4B,FAM149A,PLD5,CTTNBP2,COBL,MID1,STON2,WASF3,ANO10,MYO1D,CCDC148,WDR17,ROBO2,GCAT,ATP9A,EPS8,SLC12A6,EPHB1,RGS7,NDFIP2,GDPD5,KCNC4,COL27A1,NEDD4,NEO1,LRRC55,AFF2,SLC6A15,ERRFI1,MED12L,ARAP2,LCA5,CLYBL,CACNA1E,UCHL3,SNTB1,SKAP1,GALNT3,PTPRC,TRIB3,NSD1,OR2T33,PCDHB7,PLOD2,TERT,SRD5A3,SVIL,TUFT1,MYOM2,OCLN,SLC43A1,ATP1A3,EXPH5,FHDC1,TNFAIP8L2,LILRB1,ABAT,SLCO3A1,HMCN1,RTN1,ARHGEF10L,LGI2,RND2,PPM1E,SIPA1L2,RPS6KA2,SEC16B,LRRC6,ABI3BP,MARVELD2,ITGB3,COL19A1,LIN7A,TRPC1,JAKMIP2,KIAA1614,TLN2,MYRIP,TLR4,OR2W3,IL1RAP,NEB,SLIT2,RASGRP1,ZNF391,ATF4,KCNIP3,SKAP2,ABCC4,ANK2,JPH1,CR2,TTC22,ROR1,TCERG1L,SESN1,EML1,DYRK1B,TMEM132B,ITGBL1,P4HA2,FAM114A2,TECPR2,CCDC146,NCOA7,MAGI2,MLLT3,TC2N,CHMP4C,PCSK5,KCNV1,SV2B,MOCOS,STXBP5L,SEC24D,CYP4V2,SETBP1,ZNF215,CHSY1,FAM81A,SPINK5,SATB1,CD7,PCDHB14,KIAA1958,KIAA0895,ZBTB38,PDE10A,EBF4,HS3ST5,SMTN,LIMCH1,SLCO4C1,VGLL4,NOS3,FGFR4,CDH26,PPFIA4,WDR25,OBSCN,SDK1,PRDM1,KHDRBS2,TEX9,GPR19,STEAP1,BAIAP2,TBC1D2,PLAGL1,KIAA0355,FAT1,MFSD2A,HK2,PTPRN2,PLD1,OSBPL6,XKR4,CFH,CELSR3,XYLT1,COBLL1,TDRKH,OR51B4,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,UBTD2,DOCK2,DDX60L,SP8,ZSCAN5A,TBC1D19,FAM131B,COL22A1,UNC13B,TACC2,RPS6KL1,ZDHHC6,MYO3B,EEPD1,MAP7,MYH15,MET,SP140L,HRASLS,DPP10,PRAME,PHLDB2,UROS,PTPRU,TES,FGF12,ACO1,CD40,DOCK5,SMAD3,ARMC4,MSC,RANBP2,NRG3,PTPRJ,RNF217,GBP1,PTPRS,SOHLH2,TTC39A,MBOAT2,LIFR,CTNND2,MAST1,OR51B5,PCDH18,SLC6A9,PRSS16,BMPR2,KLHL13,ARHGEF11,GRB14,APBB1,MCTP2,CLSTN2,GABRG2,COL4A5,PRDM8,USP30,NKX6-1,SCN1B,EIF1,DSG2,KIAA0319,SGK1,TSPAN13,DHRS12,SH3PXD2B,SYK,RBMS2,ATP2B1,DLGAP1,MICAL2,RAB3B,HNF4G,LRRIQ1,ESRRG,FOXN3,GRID1,PRICKLE1,AGAP2,FNDC3A,EXOG,ZFPM2,PALLD,NAALADL2,ILDR2,MGMT,MAP1B,MKX,CTIF,EBF1,DPY19L2,CD37,FAT4,FBN1,MPP7,L3MBTL4,FMO4,THSD7B,SLC7A5,RPL4,KIF21A,GEM,CACNA2D1,FILIP1,SNPH,ZNF235 |
| 1.928e-09 | -20.07 | GO_NEURON_PROJECTION_MORPHOGENESIS | MSigDB lists | GO_NEURON_PROJECTION_MORPHOGENESIS | 391 | 77 | 17377 | 1707 |
NBL1,UGT8,CELSR3,RBFOX2,KIF5A,PLXNA2,GATA3,ENAH,NRXN1,SEMA6A,CTNNA2,EPB41L3,COL25A1,DAB2IP,CTTN,PACSIN1,ETV1,SLIT2,NTNG1,SEMA6C,NKX2-1,ATL1,GPM6A,EVL,DCC,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,TSKU,MAP2,SEMA3C,UNC5B,NRP1,LIFR,COBL,CTNND2,EFNB2,BCL11B,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,EPHB1,NEO1,CHN1,NUMBL,LRRC55,CNTN4,LRRN1,SEMA4F,SCN1B,FLRT3,SGK1,NCAM1,STXBP1,PAK1,DPYSL5,UNC5C,BDNF,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,MAP1B,RERE,DOCK7,THBS4,MATN2,SEMA3A,NKX2-8 |
| 1.977e-09 | -20.04 | signaling | biological process | GO:0023052 | 5365 | 623 | 17256 | 1658 |
ARHGAP26,DOC2A,PDE1B,GRIK2,DNAJC3,NPM1,STAT5B,CEBPA,CHAC1,DOCK3,CA8,SKI,BAG3,TGFBR3,PMAIP1,PPFIA2,RAP2A,RAB26,TSHR,CPE,SMAD9,DCC,WLS,CAP2,GJB2,TGFA,LRRK2,PRKAR2B,KCND3,FGF17,INTS6,WIPF3,ADRB1,ARHGAP28,BBC3,TMOD2,INPP5F,DIRAS1,MEF2C,SCN5A,GNG12,LATS2,ITGA6,SLK,TJP1,GPSM2,HPCAL4,CHN1,CACNB2,FLRT3,SRGAP1,CADPS2,NCAM1,STXBP1,TSPAN9,GFRA1,LRP12,CHRM3,ZNF385A,FADS1,BDNF,KCNQ3,MYO10,STAT4,ARID5B,FHL2,RYR2,HIP1,CALCRL,SNAP25,OR11H4,ARRDC4,SH3GL2,CDH17,INHBE,SELENOM,TRPC3,SHTN1,DOCK9,BTC,ZNF516,PKP2,IL13RA1,MAPK4,GRK6,NRXN1,LCP2,CDS1,GPR15,PLPP1,TLR3,CHRNA5,DACT1,CNKSR3,RTKN2,RAB27B,PERP,SCN3A,DOCK8,FZD1,MYLK3,ADM2,FZD4,KCNH5,ADCY1,WNT11,RAB38,DSP,FGFR1,MAGI3,GJC1,IRS2,CXCL10,ARHGAP21,WFS1,GPR160,APELA,WWTR1,INPP4B,TNFSF15,LRRC27,HOXB9,RAB30,CGB2,EDA2R,ROBO2,FZD8,ESRP1,CD276,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,KCNC4,TSPAN17,NEO1,PCBP4,MCF2L,BHLHA15,GHR,MYO6,ZFP36L2,FES,TRPM4,B9D1,VEGFC,RAB6B,RAPGEF2,RASA3,GAREM1,GALNT3,PTPRC,TRIB3,PCDHB7,PLPPR2,AKT3,GNAO1,XBP1,NEK11,BMP4,DOCK6,FOXA1,BTRC,CACNG3,FGF13,SYT12,LILRB1,NDRG2,ITPR2,SYT14,FAM13A,NOVA1,RND2,RPS6KA2,KCNN2,ITGB3,TBC1D32,LIN7A,TLR4,RAPGEF5,ITGB7,KCNIP3,ATF4,MARK1,GCNT2,COL4A3,ANK2,PLPP2,CR2,PLEKHA1,BATF,PLEKHB1,TSKU,SPNS1,TRIM9,INHBC,TCF7L1,KCNMB4,INSIG1,GNB4,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,ADGRA3,TC2N,ADGRL2,PRKAA2,TYRO3,RGS16,RUNX2,UBASH3B,RASL11B,IL18R1,DOK5,EFEMP1,NUMBL,SEMA4F,IGF1R,PDE10A,LRP6,ADCY6,BNIP3,PAK1,FGFR4,DPYSL5,UNC5C,BTNL9,HOMER2,EFNA3,PPFIA4,STRADB,OBSCN,SLITRK5,PDE8A,GPR19,BAIAP2,MAPKAPK2,KCNK15,GRIK4,HEYL,CSF1,PLD1,SEMA3A,SFN,PRKN,ID1,AKAP5,DOCK1,RBFOX2,RHPN2,NTRK3,OR51B4,TNKS1BP1,RADIL,PCLO,PPP1R9A,SEMA6A,CBLN1,SLC22A17,BCL6,ADGRL1,SCN2A,SNAI2,GLI1,CTH,EVL,LRRC8B,FGF12,CHRNA6,VIM,GSTO1,FRK,JAM3,SMAD3,NRG3,PTPRJ,GBP1,PTK7,ITGA2,MAOA,HGF,SEPT5,CTNND2,CNTN1,HEY1,TENM1,PCDH18,LPAR2,SLC6A9,IL32,BMPR2,GRB14,PAK5,APBB1,NLRP14,MCTP2,GABRG2,RASD1,ARHGAP44,RASD2,GTF2F2,KCNMB3,SGK1,PRICKLE2,TSPAN13,SYK,DUSP1,MOB1B,DLGAP1,LITAF,NUAK2,FERMT2,PRICKLE1,ILDR2,HOMER3,DKK1,DDAH1,CD37,DOCK7,FAT4,DLG2,SLC1A5,PTGES,KIF1B,CACNA2D1,CGN,ACVR1,LANCL3,LGR4,GATA3,PRKCA,RAC3,STK24,NCS1,MOK,CHRDL1,ATRNL1,RCAN3,DCDC1,WISP3,NR6A1,ACVR1C,DEPTOR,BNIP3L,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,GNAI1,GPR150,NCKAP1L,RASGRF2,PLK2,MAPK13,SEMA3C,UNC5B,NRP1,SPOCK3,EFNB2,MRC2,INPPL1,CELSR1,PTPRD,GABRB2,SCN8A,DHCR24,OPHN1,SLC1A3,TNFRSF10C,APBA1,TNFRSF19,RALGPS2,PIK3AP1,MYC,SREBF1,PRKG1,OPN3,GRIP1,TSPAN12,MAST4,GPR161,RIMS2,IGSF3,PTCH2,RPL26,DISC1,DCHS1,RAPGEF4,VLDLR,CDC42BPA,PLCB1,DAGLA,PMEPA1,PKN3,PELI2,WDR19,MPP2,EPHA3,AMOTL1,PCSK1N,RASAL2,TCTN2,RHOD,GPR65,PLXNA2,CHUK,DDR1,ZFYVE9,TIAM2,ASNS,SHF,DAB2IP,PDE4D,GAB2,PDK1,PREX1,PRKCQ,ATF3,ATOH1,PYGO1,ATP1B1,PATJ,DCBLD2,SNCA,ISG20,HTR7,BEX3,PRKCB,ASIC1,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,MAPK10,NR3C2,MID1,HACE1,IGFBP6,EPS8,GPR180,GABRR2,NDFIP2,RGS7,INPP1,ADGRB2,NEDD4,RASSF8,GPR155,SGK3,PRKG2,SMAD6,VAV3,SH3BP2,GSTM2,ARHGEF28,ARAP2,PXN,MPP1,CACNA1E,GUCY1A2,SKAP1,GPLD1,CEBPB,FGR,OR2T33,MCC,TUFT1,GRIN2D,LRRK1,TNFRSF17,LARP1,DDIT3,ATP1A3,ACSL1,HEBP1,KIF5A,CACNB4,DNER,KREMEN1,F3,EPCAM,ARHGEF10L,EPHB6,OR2W3,IL1RAP,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,TNK2,SESN2,SKAP2,CAPN5,YAP1,ROR1,SGK2,SERGEF,GRK3,GSN,GPRC5B,OXTR,TNFSF4,PPARGC1A,MAGI2,APBA2,PCSK5,BCL11B,GPR63,SV2B,FN1,RHOBTB1,ATP6V1E2,CD7,ADGRG6,DDIT4,PCDHB14,CA2,INAVA,BARX1,CEBPD,NOS3,PCDH10,IL17RD,GPR176,RHOQ,MSTN,SH2D2A,EDEM3,WWC1,DUSP9,HERPUD1,PLAGL1,ADGRB3,FAT1,RAB31,PTPRN2,NXPH4,TMEM117,DISP2,CREB3L2,CXCR5,SORBS1,IL15,CELSR3,ARHGAP22,CANX,DOCK2,CD53,PDZD8,UNC13B,CDC14B,RPS6KL1,ACVR2A,FHIT,GULP1,MET,ANTXR2,FER,PTPRU,PTPN6,SYNJ2BP,CD40,DOCK5,BCL11A,TRIM34,EIF4EBP1,RGS10,DISP1,LIFR,MAST1,OR51B5,TNIK,ARHGEF11,TSPAN15,REL,LRP4,TNFSF13B,COL4A5,NOTUM,BMP6,SYDE2,MCU,NKX6-1,RAB11FIP5,KCNJ4,CHN2,SCN1B,PRKCD,STC2,DSG2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,HNF4G,CRIM1,ESRRG,NR4A1,GRID1,ARHGAP32,TLR6,LEPR,GPR37,TIFA,EDA,RND3,MAP2K6,UACA,GEM,IL9R,NPHP1,MAP3K20,SNPH |
| 2.002e-09 | -20.03 | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | 3601 | 448 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,THOC5,SIDT1,GRIK2,LDLR,GATA3,FAM102B,NPM1,ENAH,DOCK3,KIAA1217,CA8,AARS,EYA4,SLC9A7,STK24,PCDH7,DNAH6,SLC22A18,PPFIA2,RAB26,CHRDL1,BEND4,VWA5A,PLTP,KLHL29,MEIS2,EML6,DCC,KLHL4,LRRK2,LRMP,DEPTOR,TNS1,KCND3,ZDHHC14,AHRR,WIPF3,PLK2,ATP7B,MAP9,DIRAS1,ZBTB20,DSEL,SERPINI1,TANC2,DNHD1,MEF2C,LRFN5,STOX2,CELSR1,PTPRD,TBC1D1,SCN8A,ITGA6,ZNF25,GTF2IRD1,BTBD9,WDFY4,DYNC1I1,BBS9,TTC30B,MECOM,MTUS1,SYCP2,NAV1,FRY,KIAA1671,NOVA2,PIK3AP1,BACE2,ZIC5,C1QL4,PRKG1,SREBF1,GRIP1,MPDZ,CADPS2,LMAN2,ALPK1,DENND1C,COL9A2,GFRA1,RIMS2,CHRM3,BOD1,HMGCR,RNF152,FADS1,KCNQ3,COL4A4,VLDLR,DCHS1,FASN,FHL2,KIAA1324L,RYR2,PEX5L,CCDC85A,ZBBX,TAF4B,OR11H4,PLCB1,CLN5,MMP15,DAGLA,BEX4,XKR9,TEX15,PKN3,ADAMTS3,ISM1,THBS4,QPCTL,EMILIN2,CLMN,CDH2,SMYD3,ACSM3,DOCK9,PLA2G4A,EPHA3,FRMPD3,NUDT10,ZNF516,TCTN2,RASAL2,FAM131C,LRRCC1,PLXNA2,BEGAIN,RGS20,PKP2,CHUK,KCTD12,GRK6,COLEC10,COL14A1,TBC1D30,SLC19A2,CCDC120,EPB41L3,SPEG,CHRNA5,ZNF438,DACT1,ALDH1L1,NBEA,DAB2IP,NAP1L3,FAM155B,SERPINH1,SYNGR3,ZNF365,DNAH5,GATM,KCNB2,SCN3A,GAB2,TRDMT1,VNN2,MYLK3,GARS,B3GALT1,SFXN4,PANK1,ADCY1,SATB2,TTC28,DSP,ASPH,ATP10D,IQCH,PRKCB,WWTR1,LAMB1,MAP3K21,ZNF704,PAM,PLEKHG1,P4HA1,ALG11,GRB10,HS3ST3B1,DBP,STON2,PURG,DENND5B,C2orf88,CCDC148,FARP1,WDR17,EDA2R,CKAP2,GLIPR1L1,KIF5C,PKN1,NDFIP2,COL27A1,LRRN1,MGAT1,GPR155,GHR,RALGAPA2,TBC1D9,GFI1,SPRY2,MED12L,TRPM4,MN1,BCL7A,SLC40A1,ARHGEF28,LCA5,CACNA1E,MCF2L2,RAPGEF2,PTPN13,ZDHHC15,AK4,GPR137C,ZIC1,HEG1,GALNT3,PTPRC,NSD1,PCDHB7,TERT,MCC,SLCO5A1,SVIL,SHOX2,CRISPLD1,FOXA1,LARP1,TLL2,ATP1A3,PHACTR3,UGT8,TRIM2,CACNG3,FAM227A,KIF5A,UGDH,ACTL8,ABAT,ABHD4,NOVA1,DNER,CACNB4,KREMEN1,HMCN1,FSTL5,PLS3,RTN1,ARHGEF10L,RND2,CPNE2,KCNN2,LRRC6,HPS1,ABI3BP,DLX6,ANKFN1,COL19A1,TMEM132E,TLN2,PTPRE,TLR4,NEB,SLIT2,RAPGEF5,ZNF391,LAMP3,TNK2,SLC3A2,MARK1,COL4A3,CAPN5,SGK2,TCERG1L,TSKU,SPNS1,TMEM132B,TCF7L1,ITGBL1,NCAM2,MAP2,GNB4,TECPR2,ERN1,CCDC146,OXTR,PPARGC1A,APBA2,MAGI2,PCSK5,PRKAA2,GPR63,MOCOS,FN1,SCART1,UBASH3B,SETBP1,RASL11B,LAMC3,ATP6V1E2,CHADL,GALNT13,ZNF215,CHSY1,MLC1,PGAP1,DOK5,GALNT1,CA2,EEF2,FRAS1,GAN,HS3ST5,LRP6,ADCY6,SLCO4C1,SNX7,PAK1,DPYSL5,GPR176,RAX,UNC5C,BTNL9,PARD3B,EDEM3,PPFIA4,WDR25,OBSCN,SLITRK5,STRADB,SDK1,PRDM1,KHDRBS2,TEX9,NAP1L5,GRIK4,PLAGL1,KIAA0355,NCR3LG1,FAT1,CSF1,MFSD2A,SLC2A6,DISP2,SEMA3A,XKR4,PANK3,CXCR5,EML5,CELSR3,XYLT1,RHPN2,TDRKH,SLC7A2,SEZ6L2,TNKS1BP1,RADIL,PPP1R9A,DOCK2,DDX60L,PCLO,ZNF362,COL22A1,UNC13B,TACC2,KAZN,PPFIBP1,REEP1,MYO3B,ZNF521,MAP7,MYH15,WWC2,POU2F2,NTNG1,SEMA6C,GLI1,DPP10,PHLDB2,FER,TMEM67,TDRD3,THSD4,VIM,FRK,DOCK5,ARMC4,RGS10,PTPRS,HGF,DISP1,CYP2U1,RNF130,LIFR,C8orf48,CTNND2,CNTN1,MAST1,OR51B5,TENM1,PCDH18,ARHGEF11,RUSC2,APBB1,GABRG2,COL4A5,CUEDC2,SEL1L3,ARHGAP44,SYDE2,SLC35F1,TTC1,CHN2,MAP1A,PRKCD,EHD3,RASD2,PRICKLE2,TSPAN13,ATP2B1,DLGAP1,LRRIQ1,CRIM1,PRICKLE1,MARS,PALLD,NAALADL2,LEPR,MAP1B,ICA1,FAT4,FBN1,THSD7B,SH3BGRL2,KIF21A,TBC1D4,NPHP1,FILIP1,SLC16A10 |
| 2.181e-09 | -19.94 | pharynx | COSMIC cancer mutations | pharynx | 2761 | 357 | 17385 | 1698 |
ARHGAP26,MYCBP2,THOC5,PPP4R4,ACVR1,TTC39B,PPFIBP2,TUBE1,NPM1,CEBPA,CADM2,PRKCA,KIAA1217,EYA4,DNAH6,PPFIA2,FAAH2,CHRDL1,KCNS3,BEND4,TBC1D8,ERGIC1,ALDH1L2,LRRK2,NFIA,DEPTOR,EFHC1,KCND3,FGF17,GPC6,ENPP1,ENPP6,RASGRF2,ALDOA,DSEL,UNC5B,DNHD1,TMEFF2,LPP,MEF2C,LRFN5,SCN5A,CELSR1,ZHX3,TBC1D1,SCN8A,ZNF25,TJP1,TNFRSF10C,APBA1,BBS9,CHD5,MCOLN2,NAV1,FRY,BACE2,FAM189A1,SRGAP1,SLC16A9,DENND1C,FAM155A,FMNL2,QSOX1,SLC37A1,TBC1D8B,SPATA6,DCHS1,RYR2,TTC30A,CALCRL,PEX5L,ZBBX,TEX15,RIMKLB,ADAMTS3,THBS4,CDH17,CLMN,IQSEC2,DHCR7,SLFN5,DOCK9,EPHA3,NUDT10,TCTN2,RASAL2,GPR65,LRRCC1,PLXNA2,RGS20,LCP2,COL14A1,ZNF827,ASNS,GPRIN1,COL25A1,DACT1,STARD4,ALDH1L1,NBEA,DAB2IP,DNAH5,KCNB2,DOCK8,FZD1,VNN2,SSH3,COL6A2,RNF145,KCNH5,SHANK2,ADCY1,WNT11,PRKCQ,PYGO1,TTC28,DSP,FGFR1,MAGI3,ISG20,ZNF396,IKZF3,IQCH,INPP4B,ZNF704,ALG11,KLF5,CTTNBP2,NR3C2,COBL,MID1,PURG,DENND5B,ROBO2,ESRP1,EPS8,C1orf226,NKAIN2,KIF5C,RGS7,NEDD4,NEO1,ATXN7L1,RALGAPA2,DYNC2H1,MYO6,NPTXR,TBC1D9,GFI1,ZFP36L2,MED12L,FES,TRPM4,PFKFB4,ARHGEF28,PXN,GSTM2,RAB6B,CACNA1E,RASA3,ATP11A,ZIC1,PTPRC,NSD1,TERT,GNAO1,SVIL,MYOM2,LARP1,PHC1,ATP1A3,EXPH5,UGT8,C20orf194,ANKRD18A,SLC2A13,MGAT5B,IKZF2,HMCN1,ANKRD42,LGI2,SIPA1L2,RUFY4,RPS6KA2,HPS1,ANKFN1,MPPED2,COL19A1,JAKMIP2,KIAA1614,CTTN,TMEM132E,ENO1,TLR4,OR2W3,NEB,SLIT2,RASGRP1,LAMP3,PGBD5,COL4A3,ANK2,GDPD1,NFE2L1,CR2,TMEM200C,ROR1,CRYBG3,GPRC5B,INSIG1,MAP2,ITGBL1,P4HA2,TIGD4,TNFRSF1A,PIK3C2B,MAGI2,FRMD5,KCNV1,ZNF395,FN1,STXBP6,SETBP1,LAMC3,CHSY1,SATB1,EFEMP1,ZBTB38,BCHE,ZNF440,SAMD11,RNF148,VGLL4,NOS3,ZNF629,CDH26,UNC5C,SLC27A2,PARD3B,MGAT4B,GPSM1,TMTC4,OBSCN,SLITRK5,SDK1,KHDRBS2,GPR19,LDHD,NEGR1,GLCE,FAT1,MFSD2A,NCR3LG1,NKX2-8,SEMA3A,OSBPL6,DMXL2,NEK10,SORBS1,DOCK1,CELSR3,PSTPIP2,COBLL1,ZNF83,SLC7A2,SEZ6L2,PIBF1,TNKS1BP1,PPP1R9A,DOCK2,SEMA6A,PCLO,CBLN1,ZSCAN5A,COL22A1,PDZD8,SLC22A17,TACC2,EEPD1,ZNF521,MAP7,STEAP3,GULP1,MET,NTNG1,SEMA6C,SP140L,GLI1,DPP10,PTPRU,VIM,DOCK5,ZNF569,WARS,SMAD3,ARMC4,RANBP2,NRG3,KPNA3,PTK7,GBP1,PTPRS,SOHLH2,MAOA,RNF130,MBOAT2,CTNND2,OR51B5,TENM1,PCDH18,ENO2,RUSC2,REL,TNFSF13B,CLSTN2,SFXN3,PPP2R3A,RPL34,RAB11FIP5,NKX6-1,KCNJ4,TECPR1,MAP1A,FUT9,TSC22D1,TFAP2A,FKBP14,KIAA1211,DLGAP1,RIN2,MICAL2,FOXN3,OGDHL,MEI1,FERMT2,C3orf70,ZFPM2,TLR6,NAALADL2,MAP1B,RERE,MKX,CTIF,EBF1,GPR37,SUGT1,ICA1,DOCK7,FAT4,ZNF214,KIAA0513,DLG2,PAX9,TBC1D4,MMP16,FILIP1,ZNF235 |
| 2.234e-09 | -19.92 | regulation of neuron projection development | biological process | GO:0010975 | 452 | 84 | 17256 | 1658 |
EPHA3,PRKN,ZSWIM5,DNM3,ID1,FGF13,PLXNA2,GATA3,HECW2,NTRK3,PPP1R9A,NCS1,STK24,RND2,RAP2A,DAB2IP,CTTN,PACSIN1,ZNF365,SLIT2,IL1RAP,FZD1,DBN1,SSH3,FZD4,DCC,LRRK2,SHANK2,PREX1,FEZ1,VIM,AMIGO1,FGFR1,MAP2,PLK2,PTK7,PTPRS,SEMA3C,INPP5F,HGF,SERPINI1,SPART,NRP1,MAGI2,COBL,CNTN1,MEF2C,UST,EFNB2,TNIK,FN1,BMPR2,ROBO2,PTPRD,LRP4,APBB1,NEDD4,ARHGAP44,NKX6-1,CHN1,SEMA4F,SCN1B,KIAA0319,ADCY6,GRIP1,FIG4,GFI1,RIMS2,FES,PAK1,LZTS3,BDNF,RAPGEF2,VLDLR,SDK1,SNAP25,BAIAP2,MAP1B,NEGR1,ADGRB3,SEMA3A,CDH2,SHOX2,SHTN1 |
| 2.302e-09 | -19.89 | LEF1_UP.V1_DN | MSigDB lists | LEF1_UP.V1_DN | 179 | 45 | 17377 | 1707 |
EFNB2,DMXL2,KCNV1,MOCOS,PLSCR4,ID1,RNF144A,GRB14,GALNT12,CYP2J2,ATP8A1,NSUN6,HERC6,TMEM53,TLR3,SLC22A18,RAB26,OPN3,GSTM3,LIMCH1,PROS1,RAB27B,CPE,MYRIP,SMPDL3A,CYP1B1,TRPM4,PAK1,DISC1,PTPN13,STAT4,ATP1B1,C4BPB,ZNF711,ID3,SH3GL2,PLOD2,CDH17,DYNC2LI1,BDH2,TNFSF15,TPM1,MLLT3,FOXA1,MEF2C |
| 2.315e-09 | -19.88 | GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 714 | 120 | 17377 | 1707 |
EPHA3,NBL1,DNM3,ID1,FGF13,AKAP5,PLXNA2,GATA3,BCL6B,NTRK3,NRXN1,RAC3,SEMA6A,CBLN1,PPP1R9A,STK24,NCS1,SKI,RND2,EOMES,RAP2A,BCL6,DAB2IP,MARCKS,CTTN,PACSIN1,ZNF488,SLIT2,SEMA6C,PRKACB,GLI1,FZD1,DBN1,SSH3,DCC,LRRK2,PREX1,YAP1,FEZ1,VIM,AMIGO1,ATOH1,FGFR1,BCL11A,NRG3,GPRC5B,PTK7,PLK2,SEMA3C,INPP5F,HGF,DLX2,OXTR,BMPR1A,NRP1,MAGI2,COBL,LZTS1,CNTN1,MEF2C,UST,BCL11B,WASF3,SEMA6B,TNIK,CELSR1,BMPR2,ROBO2,FN1,PTPRD,PLAG1,LRP4,APBB1,CLSTN2,EPHB1,GDPD5,BMP6,NEDD4,NKX6-1,EFEMP1,CHN1,NUMBL,CNTN4,SEMA4F,LRRN1,SCN1B,GATA2,FLRT3,KIAA0319,SGK1,ADCY6,FIG4,GFI1,SLC45A3,RIMS2,GPR161,FES,VEGFC,BDNF,DISC1,SLITRK2,RAPGEF2,VLDLR,SMARCD3,SLITRK5,SDK1,SNAP25,CPEB1,BAIAP2,MAP1B,NEGR1,DKK1,DOCK7,HEYL,CSF1,BMP4,SEMA3A,SHOX2,CDH2,FOXA1 |
| 2.354e-09 | -19.87 | cell morphogenesis involved in neuron differentiation | biological process | GO:0048667 | 423 | 80 | 17256 | 1658 |
CELSR3,KIF5A,RBFOX2,PLXNA2,GATA3,ENAH,PRKCA,NRXN1,SEMA6A,CTNNA2,COL25A1,ETV1,ZNF365,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,ATL1,EVL,DCC,SHANK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,TSKU,IRS2,MAP2,GRB10,SEMA3C,NRP1,UNC5B,COBL,CTNND2,MEF2C,BCL11B,EFNB2,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,SLC1A3,EPHB1,FOXG1,DOK5,NEO1,CHN1,LRRC55,NUMBL,LRRN1,SEMA4F,MAP1A,CNTN4,SCN1B,PDZD7,FLRT3,NCAM1,STXBP1,GFRA1,DPYSL5,PDLIM7,UNC5C,BDNF,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,RERE,MAP1B,DOCK7,MATN2,NKX2-8,SEMA3A,SHTN1 |
| 2.363e-09 | -19.86 | intrinsic component of membrane | cellular component | GO:0031224 | 5383 | 617 | 18223 | 1724 |
GXYLT2,FLVCR2,CNTNAP3,GRIK2,RECK,MCOLN3,CADM2,BCAN,ABHD6,NOS1AP,PCDH7,TGFBR3,FAAH2,RAB26,TMED9,TMEM37,TSHR,SMIM20,DCC,WLS,TGFA,GJB2,HACD1,ABCC2,KCND3,MFSD6,SLC7A1,ENPP1,ATP7B,ADRB1,TMEFF2,SCN5A,TMEM63C,ITGA6,SLC36A4,BNIP1,FAM189A1,BACE2,CACNB2,FLRT3,LMAN2,ST8SIA1,NCAM1,MOXD1,JAM2,TSPAN9,GFRA1,CHRM3,LRP12,HMGCR,FADS1,SLC37A1,KCNQ3,MGST3,CALCRL,RYR2,ST6GALNAC3,AIG1,SHISA2,SNAP25,OR11H4,CLN5,TMCO3,CACHD1,QPCTL,CDH17,CLMN,LAPTM4B,CDH2,TRPC3,BTC,SCAMP1,GALNT12,GALNT6,ABHD13,PKP2,IL13RA1,NRXN1,SLC19A2,CDS1,GPR15,RNF150,PLPP1,TLR3,CHRNA5,KMO,COL25A1,SYNGR3,FAM155B,RAB27B,KIAA1549,PERP,SCN3A,KCNB2,FZD1,EBPL,RNF145,FZD4,KCNH5,TRAM1L1,ADCY1,PCNX2,PXYLP1,ASPH,FGFR1,GJC1,SLC39A14,ENTPD1,GYPC,GPR160,PEMT,WFS1,PAM,ALG11,TNFSF15,PLD5,SERINC5,TMEM132C,EDA2R,ROBO2,BACE1,FZD8,CD276,BIK,UBAC2,NKAIN2,P2RY1,SLC12A6,EPHB1,ZNF219,KCNC4,TSPAN17,NEO1,LRRN1,GHR,NPTXR,ULBP1,TRPM4,RAPGEF2,ELOVL3,RASA3,ATP11A,HEG1,PTPRC,GALNT3,PCDHB7,PLPPR2,SRD5A3,OSBPL5,XBP1,SLCO5A1,DCBLD1,ATP2B4,CACNG3,SYT12,LILRB1,NRN1,ITPR2,MGAT5B,SYT14,KCNN2,TM9SF2,KCNAB1,HPS1,MARVELD2,ITGB3,TMEM86A,TMEM143,TMEM132E,TLR4,ITGB7,CD55,SLC3A2,KCNIP3,GCNT2,ABCC4,GDPD1,NFE2L1,PLPP2,CR2,TMEM200C,PLEKHB1,SPNS1,KCNMB4,INSIG1,ERN1,TNFRSF1A,ADGRA3,ADGRL2,HS6ST3,TYRO3,KCNV1,RGS16,STXBP5L,MLC1,PGAP1,IL18R1,RNF180,GALNT1,SEMA4F,IGF1R,ABCA5,FRAS1,HS3ST5,LRP6,ADCY6,BNIP3,NIPAL2,PTPRCAP,SLCO4C1,FAR2,CKAP4,TMEM178B,FGFR4,CHSY3,UNC5C,B3GLCT,BTNL9,SLC27A2,RNF170,MGAT4B,EFNA3,TMTC4,SLITRK5,SDK1,GPR19,NEGR1,GRIK4,KCNK15,MFSD2A,CSF1,SLC2A6,RNF122,SMCO4,MME,LPCAT2,XYLT1,RNF24,OR51B4,NTRK3,FAM198B,SLC7A2,SEZ6L2,PRR7,SEMA6A,SLC22A17,ZDHHC6,ZDHHC23,ADGRL1,SCN2A,TMEM56,HRASLS,TMEM67,EVA1A,TMEM65,LRRC8B,CHRNA6,JAM3,NRG3,PTPRJ,RNF217,PTK7,KCNG1,ITGA2,MAOA,PTPRS,SUSD4,MBOAT2,CNTN1,ARFGEF3,RETREG1,TENM1,PCDH18,LPAR2,SLC6A9,BMPR2,MCTP2,SELL,GABRG2,SFXN3,USP30,SLC35F1,TECPR1,FUT9,KCNMB3,TSPAN13,SLC45A3,ATP2B1,FNDC3A,NPDC1,ILDR2,SMPDL3B,CD37,TMEM237,FAT4,FMO4,DLG2,MYRF,SLC22A15,SLC1A5,PTGES,CACNA2D1,FAM171B,ACVR1,SIDT1,LGR4,ATP8A1,VAMP8,LDLR,SLC9A7,SLC16A2,SLC22A18,SERINC2,NDUFB8,KCNS3,ATRNL1,THSD1,GDAP1,ERGIC1,ACVR1C,SLC9C1,LRMP,BNIP3L,SLC25A28,ACVR2B,ZDHHC14,GPC6,GPR150,SPATA9,SFXN1,NCKAP1L,ENPP6,ENTPD7,B3GALT2,MFSD4A,DSEL,UNC5B,NRP1,EFNB2,LRFN5,SEMA6B,MRC2,ALOX5AP,CELSR1,PTPRD,GABRB2,ST6GAL1,SCN8A,DHCR24,MFSD13A,SLC25A27,SLC1A3,WDFY4,TNFRSF10C,TNFRSF19,PRRG4,MYORG,GAS1,MCOLN2,GBGT1,CNTN4,SLC7A11,MSMO1,OPN3,SCARF2,SREBF1,TSPAN12,SLC16A9,FAM155A,GPR161,IGSF3,RNF152,PTCH2,QSOX1,SLC36A1,DCHS1,VLDLR,KIAA1324L,TTYH2,RABAC1,FAM162A,TMEM74,DAGLA,MMP15,XKR9,PMEPA1,MPP2,SQLE,DHCR7,EPHA3,ELOVL4,RASAL2,TCTN2,RNF144A,ST14,GPR65,PLXNA2,MSR1,CHUK,TMEM170B,DDR1,TMEM53,ERG28,DAB2IP,PDE4D,ATP6AP1L,VNN2,B3GALT1,TMEM43,SFXN4,SHANK2,NLGN4X,ATP1B1,TRIQK,ATP10D,DCBLD2,HTR7,POPDC3,ASIC1,MAP3K21,HS3ST3B1,BMPR1A,DENND5B,ANO10,PLSCR4,GLIPR1L1,ATP9A,GPR180,GABRR2,NDFIP2,SLC35G2,GDPD5,ADGRB2,LRRC55,SOAT2,MGAT1,GPR155,RMDN2,SLC6A15,CERS4,B4GALT6,TMC7,SLC40A1,CACNA1E,AGPAT4,MPP1,TMEM126A,ZDHHC15,GPR137C,OR2T33,PLXDC2,CLDN12,GRIN2D,TNFRSF17,CERS1,OCLN,B4GALT7,SLC43A1,ATP1A3,MPZL3,UGT8,ACSL1,SLC2A13,DNER,CACNB4,SLCO3A1,KREMEN1,CHST10,FKBP11,F3,RTN1,CYP51A1,EPCAM,SLC10A7,CNNM2,TRPC1,SLC2A12,HRK,CTTN,EPHB6,GALNT18,PTPRE,OR2W3,IL1RAP,PDGFRB,LAMP3,ATL1,GPM6A,CEMIP2,JPH1,TMEM47,ROR1,TMEM132B,TMEM150B,GPRC5B,NCAM2,OXTR,TNFSF4,FNDC10,SLC9B1,FRMD5,PCSK5,GPR63,UST,SV2B,SCART1,BVES,STXBP6,ELOVL7,CYP4V2,GALNT13,SCD,CHSY1,CD7,ADGRG6,PCDHB14,SLC30A4,VSIR,NCEH1,RNF148,LRP3,PCDH10,CDH26,IL17RD,GPR176,PODXL2,SLITRK2,SDC3,CATSPERE,GALNT17,B4GALNT3,SLC46A3,STEAP1,HERPUD1,GLCE,TMEM154,ADGRB3,FAT1,NCR3LG1,TMEM117,PTPRN2,DISP2,XKR4,DIRC2,CREB3L2,CXCR5,SORBS1,IL15,CELSR3,CANX,CD53,PDZD8,REEP1,ACVR2A,STEAP3,MET,TMEM120B,HSPA2,NTNG1,SEMA6C,ALG10B,SUSD3,DPP10,ANTXR2,PTPRU,SLC39A8,C3orf52,AMIGO1,SYNJ2BP,CD40,TMPRSS9,CYP2U1,RNF130,DISP1,LIFR,OR51B5,TSPAN15,CLGN,CMTM8,LRP4,TNFSF13B,CLSTN2,FAM174B,SEL1L3,MCU,KCNJ4,SCN1B,LHFPL6,DSG2,KIAA0319,MARCH3,TNFRSF11A,RAB3B,CRIM1,SYBU,GRID1,PRRG1,GALNT14,TLR6,NAALADL2,LRAT,LEPR,DPY19L2,GPR37,MYADM,MFSD9,EDA,ACER2,THSD7B,SLC7A5,SLC18B1,IL9R,MMP16,SLC16A10,ABCG1,STOM,SNPH |
| 2.393e-09 | -19.85 | STK33_DN | MSigDB lists | STK33_DN | 249 | 56 | 17377 | 1707 |
MTG1,GPT2,RGS16,RNF144A,LPCAT2,GALNT12,PSTPIP2,FAM117B,SCD,CA8,KBTBD11,TPD52L1,BEX2,NEO1,SYDE2,CCNJ,TXNRD3,IL17D,SLC35F1,ABLIM1,ASNS,KCNN2,BACE2,KAZN,DSG2,STC2,TMEM143,ZDHHC23,FAM84B,SLCO4C1,RASGRP1,LAMP3,PNMA2,MICAL2,GPM6A,GJB2,DCHS1,JPH1,LRRK2,OGDHL,CR2,PLS1,SATB2,SHISA2,PRKAR2B,ST6GALNAC3,ARHGEF26,ID3,DDAH1,TEX15,MATN2,BDH2,KLF5,TANC2,PSPH,SLC43A1 |
| 2.638e-09 | -19.75 | cell communication | biological process | GO:0007154 | 5463 | 632 | 17256 | 1658 |
ARHGAP26,DOC2A,PDE1B,GRIK2,DNAJC3,NPM1,STAT5B,CEBPA,CHAC1,DOCK3,CA8,SKI,BAG3,TGFBR3,PMAIP1,PPFIA2,RAP2A,RAB26,TSHR,CPE,SMAD9,DCC,WLS,CAP2,GJB2,TGFA,LRRK2,PRKAR2B,FGF17,INTS6,WIPF3,ADRB1,ARHGAP28,BBC3,TMOD2,INPP5F,DIRAS1,MEF2C,SCN5A,GNG12,LATS2,ITGA6,SLK,TJP1,GPSM2,HPCAL4,CHN1,CACNB2,FLRT3,SRGAP1,CADPS2,NCAM1,STXBP1,TSPAN9,GFRA1,LRP12,CHRM3,ZNF385A,FADS1,BDNF,KCNQ3,MYO10,STAT4,ARID5B,FHL2,RYR2,HIP1,CALCRL,SNAP25,OR11H4,ARRDC4,SH3GL2,CDH17,INHBE,SELENOM,TRPC3,SHTN1,DOCK9,BTC,ZNF516,PKP2,IL13RA1,MAPK4,GRK6,NRXN1,LCP2,CDS1,GPR15,PLPP1,TLR3,CHRNA5,DACT1,CNKSR3,RTKN2,RAB27B,PERP,DOCK8,SCN3A,FZD1,MYLK3,ADM2,FZD4,KCNH5,ADCY1,WNT11,RAB38,DSP,FGFR1,MAGI3,GABARAPL1,GJC1,IRS2,CXCL10,ARHGAP21,WFS1,GPR160,APELA,WWTR1,INPP4B,TNFSF15,LRRC27,HOXB9,RAB30,CGB2,EDA2R,ROBO2,FZD8,ESRP1,CD276,CBS,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,KCNC4,TSPAN17,NEO1,PCBP4,MCF2L,BHLHA15,GHR,MYO6,ZFP36L2,FES,TRPM4,B9D1,VEGFC,RAB6B,RAPGEF2,RASA3,GAREM1,GALNT3,PTPRC,TRIB3,PCDHB7,PLPPR2,AKT3,GNAO1,XBP1,NEK11,BMP4,DOCK6,FOXA1,BTRC,CACNG3,FGF13,SYT12,LILRB1,NDRG2,ITPR2,SYT14,FAM13A,NOVA1,RND2,RPS6KA2,KCNN2,ITGB3,TBC1D32,LIN7A,TLR4,RAPGEF5,DBN1,ITGB7,KCNIP3,ATF4,MARK1,GCNT2,COL4A3,ANK2,PLPP2,CR2,PLEKHA1,BATF,SESN1,PLEKHB1,TSKU,SPNS1,TRIM9,INHBC,TCF7L1,KCNMB4,INSIG1,GNB4,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,ADGRA3,TC2N,ADGRL2,RRAGD,PRKAA2,TYRO3,RGS16,RUNX2,UBASH3B,RASL11B,IL18R1,DOK5,EFEMP1,NUMBL,IGF1R,SEMA4F,FRAS1,PDE10A,LRP6,ADCY6,BNIP3,PAK1,FGFR4,DPYSL5,UNC5C,BTNL9,HOMER2,EFNA3,PPFIA4,SLITRK5,STRADB,OBSCN,PDE8A,GPR19,BAIAP2,MAPKAPK2,GRIK4,HEYL,CSF1,PLD1,SEMA3A,SFN,PRKN,ID1,AKAP5,DOCK1,RBFOX2,RHPN2,NTRK3,OR51B4,TNKS1BP1,RADIL,PCLO,PPP1R9A,SEMA6A,CBLN1,SLC22A17,BCL6,ADGRL1,SCN2A,SNAI2,GLI1,CTH,EVL,LRRC8B,FGF12,CHRNA6,VIM,GSTO1,FRK,JAM3,SMAD3,NRG3,PTPRJ,GBP1,PTK7,ITGA2,MAOA,HGF,SEPT5,CTNND2,CNTN1,HEY1,TENM1,PCDH18,LPAR2,SLC6A9,IL32,BMPR2,GRB14,PAK5,APBB1,NLRP14,MCTP2,GABRG2,RASD1,ARHGAP44,RASD2,GTF2F2,KCNMB3,SGK1,PRICKLE2,TSPAN13,SYK,ATP2B1,DUSP1,MOB1B,DLGAP1,LITAF,NUAK2,FERMT2,PRICKLE1,ILDR2,HOMER3,DKK1,DDAH1,CD37,DOCK7,FAT4,DLG2,SLC1A5,PTGES,KIF1B,CACNA2D1,CGN,ACVR1,LANCL3,LGR4,GATA3,PRKCA,RAC3,STK24,NCS1,MOK,CHRDL1,ATRNL1,RCAN3,GDAP1,DCDC1,WISP3,NR6A1,ACVR1C,DEPTOR,BNIP3L,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,GNAI1,GPR150,NCKAP1L,RASGRF2,PLK2,MAPK13,SEMA3C,UNC5B,NRP1,SPOCK3,EFNB2,MRC2,INPPL1,CELSR1,PTPRD,GABRB2,SCN8A,DHCR24,OPHN1,SLC1A3,TNFRSF10C,APBA1,TNFRSF19,RALGPS2,PIK3AP1,MYC,SREBF1,PRKG1,OPN3,GRIP1,TSPAN12,MAST4,GPR161,RIMS2,IGSF3,RNF152,PTCH2,RPL26,DISC1,DCHS1,RAPGEF4,VLDLR,CDC42BPA,PLCB1,DAGLA,PMEPA1,PKN3,PELI2,WDR19,MPP2,EPHA3,AMOTL1,PCSK1N,RASAL2,TCTN2,RHOD,GPR65,PLXNA2,CHUK,DDR1,ZFYVE9,TIAM2,ASNS,SHF,DAB2IP,PDE4D,GAB2,PDK1,PREX1,PRKCQ,ATF3,ATOH1,PYGO1,ATP1B1,PATJ,DCBLD2,SNCA,ISG20,HTR7,BEX3,PRKCB,ASIC1,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,ATG5,MAPK10,NR3C2,MID1,HACE1,IGFBP6,EPS8,GPR180,GABRR2,NDFIP2,RGS7,INPP1,ADGRB2,NEDD4,RASSF8,GPR155,SGK3,PRKG2,SMAD6,VAV3,SH3BP2,GSTM2,ARHGEF28,ARAP2,PXN,MPP1,CACNA1E,GUCY1A2,SKAP1,GPLD1,CEBPB,FGR,OR2T33,MCC,TUFT1,GRIN2D,LRRK1,TNFRSF17,LARP1,DDIT3,ATP1A3,ACSL1,HEBP1,KIF5A,CACNB4,DNER,KREMEN1,F3,EPCAM,ARHGEF10L,EPHB6,OR2W3,IL1RAP,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,TNK2,SESN2,SKAP2,CAPN5,YAP1,ROR1,SGK2,SERGEF,GRK3,GSN,GPRC5B,OXTR,TNFSF4,PPARGC1A,MAGI2,APBA2,PCSK5,BCL11B,GPR63,SV2B,FN1,RHOBTB1,ATP6V1E2,CD7,ADGRG6,DDIT4,PCDHB14,CA2,INAVA,BARX1,CEBPD,NOS3,PCDH10,IL17RD,GPR176,RHOQ,MSTN,SH2D2A,EDEM3,WWC1,DUSP9,HERPUD1,PLAGL1,ADGRB3,FAT1,RAB31,PTPRN2,NXPH4,TMEM117,DISP2,CREB3L2,CXCR5,SORBS1,IL15,CELSR3,ARHGAP22,CANX,DOCK2,CD53,PDZD8,UNC13B,CDC14B,RPS6KL1,ACVR2A,FHIT,GULP1,MET,ANTXR2,FER,PTPRU,PTPN6,SYNJ2BP,CD40,DOCK5,BCL11A,TRIM34,EIF4EBP1,RGS10,DISP1,LIFR,MAST1,OR51B5,TNIK,ARHGEF11,TSPAN15,REL,LRP4,TNFSF13B,COL4A5,NOTUM,BMP6,SYDE2,MCU,NKX6-1,RAB11FIP5,CHN2,SCN1B,PRKCD,STC2,DSG2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,CRIM1,HNF4G,ESRRG,NR4A1,GRID1,MARS,ARHGAP32,TLR6,LEPR,GPR37,TIFA,EDA,RND3,MAP2K6,CTSV,UACA,GEM,IL9R,NPHP1,MAP3K20,SNPH |
| 2.649e-09 | -19.75 | large_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-carcinoma-adenocarcinoma | 16678 | 1670 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 2.696e-09 | -19.73 | synapse part | cellular component | GO:0044456 | 734 | 119 | 18223 | 1724 |
DOC2A,DMXL2,PRKN,DNM3,CACNG3,SCAMP1,GRIK2,PRSS12,SYT12,VAMP8,ADD2,KCTD12,CANX,NRXN1,PRR7,PPP1R9A,CBLN1,PCLO,CTNNA2,NCS1,EPB41L3,CHRNA5,UNC13B,KCNN2,PPFIA2,RAB26,ADGRL1,LIN7A,CTTN,PACSIN1,RAB27B,SYNGR3,CPE,GPM6A,KCNIP3,ANK2,CAP2,SHANK2,LRRK2,DNAJC6,CHRNA6,NLGN4X,PRKAR2B,ROR1,SNCA,TRIM9,CAMK2N1,MAP2,ITGA2,RGS10,PTPRS,SEPT5,APBA2,CTTNBP2,MAGI2,STON2,LZTS1,MEF2C,SV2B,FARP1,SLC6A9,BMPR2,GABRB2,APBB1,LRP4,BLVRB,OPHN1,CLSTN2,GABRG2,PSD3,GABRR2,P2RY1,APBA1,PFN2,KCNC4,ARHGAP44,NEDD4,KCNJ4,SEMA4F,FLRT3,GRIP1,MPDZ,BNIP3,CADPS2,STXBP1,SEPT3,RIMS2,ATP2B1,CHRM3,DLGAP1,LZTS3,BDNF,DISC1,SLC40A1,RAB3B,HOMER2,GRID1,PPFIA4,HIP1,RABAC1,SNAP25,ARHGAP32,BAIAP2,CPEB1,HOMER3,MAP1B,DAGLA,GRIK4,ICA1,ADGRB3,SH3GL2,FCHO2,MPP2,PTPRN2,GRIN2D,DLG2,CDH2,MME,SNPH |
| 2.700e-09 | -19.73 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | 677 | 115 | 17377 | 1707 |
ACSL1,ADAL,RECK,PLEKHA5,MYO1B,ZNF311,TNFAIP8L2,ASS1,TUBE1,TMEM170B,ITPR2,CHAC1,LACC1,KIF21B,PRKCA,AARS,EPB41L3,SIPA1L2,ASNS,PMAIP1,RAP2A,TMEM143,BCL6,MAP7,LIN7A,CTTN,PDE4D,PTPRE,CTH,DBN1,ANTXR2,CD55,SLC3A2,GARS,SESN2,TUBA1A,TMEM65,TES,ALDH1L2,LRMP,PREX1,NFE2L1,BNIP3L,EFHC1,ATF3,PLEKHA1,MFSD6,CD40,TPK1,ZNF569,BATF3,WARS,SLC7A1,ADRB1,GRB10,NRP1,PSPH,LPP,HACE1,CARS,GPT2,RGS16,INPPL1,CELSR1,ALOX5AP,ITPRIP,SEC24D,ZCCHC24,BLVRB,CBS,SLC12A6,PHGDH,SEL1L3,INPP1,IL18R1,PHLDA2,GRPEL2,NEDD4,DDIT4,SLC7A11,STC2,EIF1,KLF9,FIG4,NCEH1,PCK2,ERRFI1,SYK,MICAL2,ARAP2,SH3BP2,GSTM2,PLEKHA8,RAPGEF2,VLDLR,TCEA3,MAFB,HIP1,PHACTR2,MARS,SHISA2,CDC42BPA,SNTB1,ARRDC4,MBNL2,CEBPB,PTPRC,TRIB3,CD37,TMEM154,KIAA0355,SRD5A3,SLC22A15,KIF1B,DIRC2 |
| 2.815e-09 | -19.69 | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | 290 | 62 | 17377 | 1707 |
EFNB2,PLSCR4,RASAL2,PTPN21,DHCR24,SETBP1,COL18A1,DNER,PCLO,MECOM,SKI,ABLIM1,IGF1R,ZNF354A,BACE2,FLRT3,FAM168A,DSG2,MAP7,NBEA,SLC6A15,MPDZ,SLC16A9,TMEM37,MET,PRR16,JAM2,DOCK8,GDAP1,RHOQ,MARK1,ALDH2,LCA5,CRIM1,FZD4,FOXN3,TNS1,PRKCQ,PRDM1,ATP1B1,PLEKHA1,TTLL7,JAM3,SPATA7,C9orf116,AK1,TCF7L1,HLF,GPRC5B,PLXDC2,MATN2,PCGF2,ZBTB20,MAPK13,MBOAT2,SMYD3,IL9R,OCLN,FILIP1,DOCK9,LPP,CNTN1 |
| 2.845e-09 | -19.68 | GSE22886_NAIVE_BCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_DC_UP | 174 | 44 | 17377 | 1707 |
MVK,SIDT1,IL15,FBXO4,MCTP2,SELL,DDR1,NIPSNAP3B,RPL13A,TIAM2,RPL34,HOPX,TBC1D19,SEMA4F,BACE2,RPS11,FRAS1,EHD3,MARCH3,PTPRCAP,RRAS2,RPS23,DUSP1,VAV3,BCL7A,GPM6A,RPL21,CR2,TAF4B,SKAP1,ISG20,BCL11A,GALNT3,SMAD3,CD37,BACH2,RPL28,KIAA0355,PIK3C2B,SPRY4,NR3C2,MID1,PHC1,MEF2C |
| 2.979e-09 | -19.63 | KOYAMA_SEMA3B_TARGETS_UP | MSigDB lists | KOYAMA_SEMA3B_TARGETS_UP | 257 | 57 | 17377 | 1707 |
LPAR2,LANCL3,IGFBP6,CNTNAP3,GRB14,GALNT6,PLAG1,MCOLN3,OPHN1,PKP2,KIF5C,TUBE1,CEBPA,CREB5,CHAC1,NOVA1,TPD52L1,DDIT4,SLC35F1,SPEG,IKZF5,FRAS1,STC2,RAB26,SMTN,DYNC2H1,SP140,RAPGEF5,FMNL2,SP140L,ZNF629,RABAC1,ZNF618,STEAP1,MAP1B,TSKU,TBC1D2,HEG1,DCBLD2,BEX4,CAMK2N1,INHBC,DDAH1,KIAA0355,ITGBL1,EMILIN2,PLEKHG1,BDH2,HK2,TMEM117,HOXD13,SERPINI1,SUSD4,FBXO27,MID1,PANK3,TPT1 |
| 3.118e-09 | -19.59 | regulation of signal transduction | biological process | GO:0009966 | 3238 | 402 | 17256 | 1658 |
ARHGAP26,ACVR1,DUSP8,LGR4,GRIK2,GATA3,CTBP2,CHAC1,PRKCA,ABHD6,RAC3,EYA4,STK24,NOS1AP,SKI,TYMP,TGFBR3,PMAIP1,ZFYVE28,RAP2A,CHRDL1,RCAN3,NKX2-1,WISP3,WLS,TGFA,LRRK2,DEPTOR,ACVR2B,FGF17,GPC6,ARHGEF26,GNAI1,ENPP1,SH3RF1,CCBE1,PLK2,RASGRF2,ADRB1,BMP1,ARHGAP28,BBC3,TMOD2,INPP5F,DIRAS1,SPRY4,NRP1,UNC5B,SPART,MEF2C,LATS2,ITGA6,OPHN1,TNFRSF10C,TNFRSF19,CHD5,GAS1,MYORG,MECOM,IL17D,CHN1,RALGPS2,PIK3AP1,MYC,FLRT3,C1QL4,PRELID1,SRGAP1,RIMS2,GPR161,ZNF385A,RNF152,HMGCR,PTCH2,RPL26,BDNF,DISC1,HIP1,PEX5L,SHISA2,TAF4B,PLCB1,FAM162A,SH3GL2,PMEPA1,ADAMTS3,PELI2,THBS4,INHBE,SPRED3,IQSEC2,CDH2,EPHA3,NBL1,BTC,RASAL2,RHOD,GPR65,RGS20,CHUK,GRK6,TMEM170B,NRXN1,DDR1,TIAM2,TLR3,DACT1,CNKSR3,MAGEA3,SHF,DAB2IP,PDE4D,FZD1,FZD4,ADM2,SHANK2,PREX1,NLGN4X,ATF3,PRKCQ,WNT11,CBY1,FGFR1,MAGI3,SNCA,IRS2,CXCL10,ARHGAP21,PRKCB,WFS1,APELA,WWTR1,PLEKHG1,MAP3K21,TNFSF15,GRB10,BMPR1A,MAPK10,MID1,CGB2,FARP1,C1QTNF3,EDA2R,IGFBP6,FZD8,EPS8,BIK,PSD3,GAS6,P2RY1,PKN1,EPHB1,RGS7,NDFIP2,GDPD5,TPD52L1,TSPAN17,PHLDA2,NEDD4,NEO1,RGS17,MCF2L,GHR,SGK3,RALGAPA2,DYNC2H1,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,PARP9,TRPM4,VEGFC,VAV3,SH3BP2,PXN,ARAP2,ARHGEF28,GSTM2,PTPN13,MCF2L2,RAPGEF2,RASA3,GAREM1,RACK1,SKAP1,ZIC1,PTPRC,TRIB3,FGR,TERT,AKT3,XBP1,PCGF2,MCC,BMP4,LRRK1,SHOX2,DDIT3,ATP2B4,FOXA1,BTRC,TPT1,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,HDGFL3,ABAT,FAM13A,KREMEN1,F3,GSDME,ARHGEF10L,SIPA1L2,AKAP7,ITGB3,HRK,EPHB6,CTTN,PTPRE,ENO1,TLR4,SLIT2,PDGFRB,RASGRP1,PRKACB,CYP1B1,CD55,ATF4,GCNT2,SESN2,SKAP2,JPH1,YAP1,PLEKHA1,ROR1,SESN1,TSKU,INHBC,GSN,TCF7L1,GPRC5B,INSIG1,HPSE,ERN1,TNFRSF1A,DLX2,PPARGC1A,TNFSF4,MAGI2,MLLT3,RRAGD,PRKAA2,TYRO3,RGS16,RUNX2,FN1,LGALS3,RHOBTB1,UBASH3B,RASL11B,SORBS3,CHSY1,IL18R1,DOK5,DDIT4,EFEMP1,IGF1R,GATA2,PDE10A,LRP6,INAVA,BNIP3,FBXL2,BARX1,NOS3,PAK1,FGFR4,ATP5IF1,MID2,RHOQ,MSTN,SH2D2A,HOMER2,SPATA13,OBSCN,WWC1,STRADB,DUSP9,PDE8A,PRDM1,HERPUD1,BAIAP2,MAPKAPK2,RIPOR2,CSF1,HEYL,SH3BP4,EGFL7,SEMA3A,SFN,PRKN,SORBS1,ID1,NEK10,AVPI1,AKAP5,IL15,ARHGAP22,NTRK3,PIBF1,CBLN1,CYP26A1,UNC13B,BCL6,ACVR2A,WWC2,MET,SNAI2,GLI1,CTH,IGFBP3,INTU,PRAME,FER,NOP53,PTPN6,FGF12,RNF125,GSTO1,SYNJ2BP,CD40,CAMK2N1,SMAD3,NRG3,PTPRJ,GBP1,RBPMS2,RGS10,DUSP19,PTPRS,HGF,DISP1,LIFR,CTNND2,HEY1,ARFGEF3,TENM1,TNIK,DYRK3,NECAB2,IL32,BMPR2,TSPAN15,ARHGEF11,PAK5,GRB14,REL,LRP4,CMTM8,NLRP14,TNFSF13B,NOTUM,BMP6,ARHGAP44,SYDE2,CHN2,PRKCD,STC2,RASD2,AFAP1L2,IQGAP3,TNFRSF11A,TESPA1,SYK,PCSK6,DUSP1,MSX1,CYTH3,LITAF,ASAP3,PRICKLE1,AGAP2,ARHGAP32,TLR6,SMPDL3B,DKK1,GPR37,MYADM,TMEM237,EDA,NACC2,FBN1,GCSAM,MPP7,PRCP,MAP2K6,UACA,MAP3K20 |
| 3.250e-09 | -19.54 | PDZ_sf | interpro domains | IPR036034 | 151 | 40 | 18492 | 1811 |
FRMPD3,ARHGEF11,RHPN2,TJP1,APBA1,RADIL,PPP1R9A,PCLO,TIAM2,SIPA1L2,PDZD8,PDZD7,CNKSR3,GRIP1,LIN7A,MPDZ,MAST4,RIMS2,PDLIM7,INTU,SYNPO2,PARD3B,RAPGEF2,PTPN13,MPP1,SHANK2,DEPTOR,PREX1,SYNJ2BP,SNTB1,MAGI3,ARHGAP21,PDLIM3,MPP7,AHNAK2,MPP2,DLG2,MAGI2,APBA2,MAST1 |
| 3.278e-09 | -19.54 | regulation of cell projection organization | biological process | GO:0031344 | 639 | 108 | 17256 | 1658 |
EPHA3,PRKN,DNM3,ID1,ZSWIM5,FGF13,PLXNA2,HECW2,GATA3,NTRK3,TBC1D30,PPP1R9A,NCS1,STK24,TBC1D19,RND2,RAP2A,DAB2IP,CTTN,PACSIN1,ZNF365,SLIT2,IL1RAP,FZD1,TBC1D8,DBN1,FER,SSH3,GPM6A,EVL,DCC,FZD4,SHANK2,LRRK2,PREX1,FEZ1,VIM,AMIGO1,TBC1D16,FGFR1,MAP2,PLK2,PTK7,ITGA2,PTPRS,HGF,KLF5,SEMA3C,INPP5F,SERPINI1,ATG5,NRP1,SPART,MAGI2,COBL,CNTN1,MEF2C,EFNB2,UST,TENM1,TNIK,FN1,ROBO2,BMPR2,TBC1D1,PTPRD,APBB1,EPS8,LRP4,PFN2,ARHGAP44,NEDD4,NKX6-1,CHN1,SEMA4F,SCN1B,PRKCD,KIAA0319,GRIP1,ADCY6,FIG4,GFI1,SPRY2,FES,RIMS2,PAK1,BDNF,LZTS3,RHOQ,MYO10,RAPGEF2,VLDLR,PLS1,SNAP25,SDK1,BAIAP2,MAP1B,NEGR1,TBC1D2,RIPOR2,ADGRB3,DYNC2LI1,PLD1,FNBP1L,SEMA3A,CDH2,SHOX2,SHTN1 |
| 3.305e-09 | -19.53 | breast-carcinoma | COSMIC cancer mutations | breast-carcinoma | 15509 | 1582 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,KLF12,ERN1,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,SNCA,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,TMEM154,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,C3orf52,TCEAL3,AMIGO1,CD40,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,SLX1B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,ACTA2,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,MYO10,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,JAKMIP3,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,OR51B4,ZNF83,SLC7A2,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,RPL13A,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,ZNF311,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,EBF4,FAM107B,NCEH1,MORN4,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,DPP10,FER,PHLDB2,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,PRCP,MAP2K6,THSD7B,SLC7A5,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 3.374e-09 | -19.51 | skin-malignant_melanoma | COSMIC cancer mutations | skin-malignant_melanoma | 16216 | 1637 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,C1orf53,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,PLD5,KLHL31,HOXB9,SERINC5,FARP1,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 3.414e-09 | -19.50 | upper_aerodigestive_tract-mouth-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma | 6579 | 754 | 17385 | 1698 |
ARHGAP26,TRIM16L,PDE1B,GRIK2,PRSS12,RECK,TUBE1,CTBP2,BCAN,DOCK3,KIAA1217,SNX9,CA8,EYA4,SKI,TXNDC5,IKZF5,DNAH6,PPFIA2,FAAH2,RAP2A,RAB26,PPP2R2B,COG3,KLHL29,TSHR,POU3F3,RWDD2A,DCC,TGFA,GJB2,LRRK2,FEZ1,PRKAR2B,ABCC2,KCND3,F12,ENPP1,WIPF3,ATP7B,ADRB1,DIRAS1,ZBTB20,TMOD2,DNHD1,VASH2,C12orf77,CARS,SCN5A,LATS2,TMEM63C,STOX2,ITGA6,TJP1,SLC36A4,BTBD9,FOXG1,BBS9,CHN1,SYCP2,FRY,SRGAP1,ALPK1,LOXL4,DENND1C,FIGN,NCAM1,ZNF518B,GLIS1,GFRA1,CHRM3,FADS1,KCNQ3,MYO10,STAT4,FASN,RYR2,HIP1,PLS1,SNAP25,ZBBX,ARRDC4,SPATA7,TEX15,TMCO3,RIMKLB,CLMN,LAPTM4B,SPRED3,CDH2,DOCK9,TFCP2L1,BTC,NUDT10,DNM3,ZNF516,GALNT12,MYO1B,LRRCC1,ABHD13,RGS20,ADD2,GRK6,LCP2,GPR15,EPB41L3,RNF150,GPRIN1,CNKSR3,COL25A1,DACT1,MAGEA3,ALDH1L1,RTKN2,FAM155B,RAB27B,SYNGR3,ZNF365,DNAH5,MYT1,KCNB2,SCN3A,DOCK8,FZD1,C3orf67,SSH3,GARS,COL6A2,GAPDH,RNF145,EBPL,PFKFB2,KCNH5,ADCY1,TTC28,DSP,ZNF618,MAGI3,ENTPD1,WFS1,LAMB1,PLEKHG1,RCN3,FAM149A,DBP,KLHL31,LRRC27,SERINC5,CCDC148,TMEM132C,WDR17,ROBO2,GCAT,ESRP1,IPO5,UBAC2,NKAIN2,CBS,SLC12A6,P2RY1,PKN1,EPHB1,ZNF219,COL27A1,LRRN1,GAS2L3,MYO6,NPTXR,C15orf41,MED12L,PARP9,TRPM4,MN1,CLYBL,MCF2L2,RAPGEF2,SNTB1,HEG1,PTPRC,NSD1,PCDHB7,OSBPL5,NEK11,PIP5KL1,CMPK2,DOCK6,ATP2B4,DCBLD1,FOXA1,PHC1,TLL2,TPT1,NBPF4,FGF13,FAM227A,TRIM16,SYT12,FHDC1,LMCD1,NDRG2,LILRB1,MGAT5B,FAM13A,NOVA1,FSTL5,ANKRD42,RUFY4,FKBP9,TM9SF2,EOMES,CPVL,KCNAB1,SEC16B,KCNN2,HPS1,TMEM86A,ITGB3,TMEM143,MPPED2,COL19A1,JAKMIP2,TLN2,TMEM132E,ENO1,TLR4,ETV1,NEB,RAPGEF5,PGBD5,DBN1,ITGB7,SLC3A2,KCNIP3,COL4A3,ANK2,TMEM200C,CR2,TTC22,BATF,TRIM9,KCNMB4,TECPR2,ERN1,TIGD4,PIK3C2B,TC2N,HS6ST3,LONRF1,PRKAA2,KCNV1,RUNX2,STXBP5L,SETBP1,RASL11B,SORBS3,ZNF215,PFN2,MLC1,IL18R1,PGAP1,DOK5,SPIRE1,FHOD3,HSPA12B,EFEMP1,RNF180,NUMBL,ZBTB38,SEMA4F,FRAS1,PDE10A,SAMD11,HS3ST5,ADCY6,BNIP3,SLCO4C1,FAR2,FBXL2,VGLL4,CKAP4,PAK1,FGFR4,CHSY3,UNC5C,SLC27A2,RNF170,MGAT4B,TCEA3,SPATA13,OBSCN,SLITRK5,SDK1,LDHD,BAIAP2,TBC1D2,GRIK4,ATPAF2,HEYL,MFSD2A,SLC2A6,PLD1,SEMA3A,MME,SIX2,XYLT1,NTRK3,FAM198B,LPIN3,SEZ6L2,KIF21B,DENND3,RADIL,PPP1R9A,PCLO,CYP26A1,ZNF362,SLC22A17,TACC2,ZDHHC6,EEPD1,ZDHHC23,MYH15,SCN2A,FAM78B,CTH,GLI1,HRASLS,INTU,CSN2,TDRD3,THSD4,PRDM13,VIM,RARRES2,SMAD3,RANBP2,NRG3,ANKRD31,RNF217,PTK7,ITGA2,ABI3,PTPRS,MBOAT2,ZNF701,CTNND2,CNTN1,PCDH18,BMPR2,APBB1,MCTP2,SLC35F1,TECPR1,MAP1A,FUT9,RASD2,TFAP2A,GTF2F2,TSC22D1,SGK1,PRICKLE2,SH3PXD2B,KLF9,SYK,KIAA1211,ATP2B1,CES3,MICAL2,FERMT2,TGDS,FNDC3A,PALLD,HOMER3,DDAH1,DOCK7,FAT4,FBN1,ZNF808,SLC22A15,PAX9,THAP10,SLC1A5,TBC1D4,KIF1B,ZNF235,FAM171B,CGN,ACVR1,PPP4R4,DUSP8,SIDT1,LGR4,ATP8A1,LDLR,PPFIBP2,DACH2,RAC3,AARS,NCS1,TRPS1,ZFYVE28,SLC16A2,SERINC2,KCNS3,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,THSD1,TBC1D8,GLDC,ERGIC1,EML6,DCDC1,ACVR1C,KLHL4,DEPTOR,ZDHHC14,AHRR,ENPP6,PLK2,RASGRF2,CCBE1,SEMA3C,MAPK13,DSEL,NRP1,TANC2,UNC5B,LZTS1,SEMA6B,LRFN5,MRC2,INPPL1,FAM124A,CELSR1,EHHADH,PTPRD,TBC1D1,SCN8A,OLAH,SLC25A27,OPHN1,GTF2IRD1,WDFY4,SLC1A3,APBA1,GAS1,MTUS1,MCOLN2,ABLIM1,NAV1,NOVA2,C1QL4,VWDE,SREBF1,PRKG1,CPXM2,MPDZ,PRR16,COL9A2,IGSF3,PTCH2,QSOX1,TBC1D8B,COL4A4,RAPGEF4,DCHS1,PACSIN3,KIAA1324L,TTC30A,CCDC85A,CDC42BPA,PLCB1,ZNF558,TMEM74,MMP15,DAGLA,PLEKHH2,PMEPA1,CECR2,LRRIQ3,MATN2,DYNC2LI1,SQLE,SFMBT1,SMYD3,EPHA3,TBKBP1,AMOTL1,PCSK1N,ELOVL4,ST14,RNF144A,CCDC110,ZNF311,MSR1,CHUK,DDR1,COL14A1,TIAM2,CCDC120,NELL2,ZNF827,SPEG,ASNS,SHF,NBEA,SERPINH1,ATP6AP1L,B3GALT1,SHANK2,PREX1,NLGN4X,SATB2,ZNF396,ZNF711,IKZF3,PRKCB,CCNA1,KLF5,BMPR1A,STON2,MID1,COBL,KCTD1,DENND5B,MYO1D,ANKRD13D,EPS8,PRSS35,HERC5,KIF5C,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RASSF8,RGS17,LRRC55,SOAT2,MGAT1,AFF2,RALGAPA2,SLC6A15,DYNC2H1,TBC1D9,GFI1,SEPT3,SLC40A1,ALDH2,ARAP2,PXN,CACNA1E,PTPN13,GUCY1A2,GPR137C,ZIC1,TERT,NUTM2A,TUFT1,SVIL,GRIN2D,MYOM2,OCLN,DDIT3,B4GALT7,ATP1A3,EXPH5,MVK,ACSL1,UGT8,PTPN21,C20orf194,KREMEN1,HMCN1,CEP85L,RTN1,LGI2,EPCAM,ADPRHL1,ARHGEF10L,SIPA1L2,LRRC6,ANKFN1,POF1B,CNNM2,TRPC1,PTPRE,FANK1,SLIT2,PDGFRB,RASGRP1,TNK2,ATL1,GPM6A,SESN2,ROR1,TMEM47,SGK2,RNF44,GPRC5B,NCAM2,FAM114A2,CCDC169,NCOA7,OXTR,PPARGC1A,MAGI2,SV2B,ZNF395,FN1,SEC24D,STXBP6,FBXO4,RIMKLA,LAMC3,ATP6V1E2,CHADL,FAM81A,SPINK5,PHGDH,SATB1,CD7,PCDHB14,EEF2,EBF4,FAM107B,LIMCH1,CAND2,NOS3,ZNF629,GPR176,PCDH10,SLITRK2,PARD3B,GSTM4,SDC3,DUSP9,WWC1,B4GALNT3,GLCE,KIAA0355,FCHO2,FAT1,NCR3LG1,RAI14,TMEM117,PTPRN2,DISP2,FNBP1L,NKX2-8,OSBPL6,EML5,SORBS1,CELSR3,PLEKHA5,ARHGAP22,HECW2,COL18A1,BCL6B,PIBF1,DOCK2,SCIN,COL22A1,KCTD15,UNC13B,KAZN,PPFIBP1,ZNF521,MAP7,ACVR2A,STEAP3,MDH1B,TMEM120B,SEMA6C,PRAME,PTPRU,PTPN6,TES,MVD,CD40,TTLL7,DOCK5,WARS,CAMK2N1,MSC,LMLN,BACH2,EIF4EBP1,TMPRSS9,CYP2U1,LIFR,MAST1,PRSS16,ARHGEF11,CLGN,TSPAN15,ARL15,LRP4,NSUN6,TNFSF13B,IGF2BP2,CUEDC2,OVOL2,SEL1L3,BMP6,SYDE2,RAB11FIP5,NKX6-1,KCNJ4,SCN1B,PRKCD,DSG2,STC2,KIAA0319,MARCH3,AFAP1L2,IQGAP3,RRAS2,RIN2,CARD6,RAB3B,HNF4G,CRIM1,NR4A1,OGDHL,GRID1,ASAP3,MEI1,PHACTR2,ARHGAP32,ZFPM2,GALNT14,NAALADL2,LEPR,MAP1B,RERE,CTIF,DPY19L2,ADAMTS17,NACC2,THSD7B,SLC7A5,UACA,KIF21A,GEM,IL9R,MMP16,NPHP1 |
| 3.424e-09 | -19.49 | astrocytoma_Grade_IV | COSMIC cancer mutations | astrocytoma_Grade_IV | 16366 | 1648 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,OR11H4,TAF4B,MBNL2,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,CACNB4,IKZF2,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH,STOM |
| 3.458e-09 | -19.48 | malignant_melanoma | COSMIC cancer mutations | malignant_melanoma | 16380 | 1649 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,C1orf53,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 3.656e-09 | -19.43 | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | MSigDB lists | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP | 333 | 68 | 17377 | 1707 |
NBL1,DNM3,CFH,RECK,GPR65,XYLT1,LMCD1,MSR1,KCTD12,LCP2,COL14A1,FKBP11,CD53,PLS3,CPVL,DACT1,TRPC1,PROS1,SERPINH1,ETV1,SNAI2,PDGFRB,IGFBP3,CD55,MEIS2,COL6A2,ABCC4,SKAP2,TMEM47,RARRES2,ROR1,ATP10D,JAM3,EML1,ENTPD1,TDO2,ITGBL1,GBP1,LAMB1,WWTR1,AHNAK2,PAM,NRP1,TNFSF4,MEF2C,HEY1,MRC2,PLSCR4,FN1,GAS1,PDE10A,SGK1,MICAL2,FOXN3,MAFB,FERMT2,C1R,ZFPM2,PALLD,MAP1B,HEG1,PTPRC,FBN1,PMEPA1,AKT3,GEM,SHOX2,MME |
| 3.926e-09 | -19.36 | regulation of neuron differentiation | biological process | GO:0045664 | 602 | 103 | 17256 | 1658 |
EPHA3,PRKN,NBL1,ZSWIM5,DNM3,ID1,FGF13,PLXNA2,GATA3,HECW2,NTRK3,RAC3,PPP1R9A,STK24,NCS1,RND2,EOMES,RAP2A,BCL6,DAB2IP,CTTN,PACSIN1,ZNF365,SLIT2,IL1RAP,FZD1,DBN1,SSH3,FZD4,DCC,SHANK2,LRRK2,PREX1,FEZ1,VIM,AMIGO1,ATOH1,FGFR1,GPRC5B,MAP2,PLK2,PTK7,PTPRS,SEMA3C,SERPINI1,INPP5F,HGF,DLX2,SPART,NRP1,MAGI2,COBL,CNTN1,MEF2C,BCL11B,UST,EFNB2,TNIK,FN1,BMPR2,ROBO2,PTPRD,LRP4,APBB1,GDPD5,FOXG1,BMP6,NEDD4,ARHGAP44,NKX6-1,CHN1,CNTN4,SEMA4F,GATA2,SCN1B,KIAA0319,ADCY6,GRIP1,FIG4,GFI1,RIMS2,FES,PAK1,LZTS3,BDNF,RAPGEF2,VLDLR,EFNA3,SDK1,SNAP25,BAIAP2,MAP1B,DKK1,NEGR1,ID3,ADGRB3,HEYL,BMP4,SEMA3A,CDH2,SHOX2,SHTN1,FOXA1 |
| 3.995e-09 | -19.34 | chr13q32 | MSigDB lists | chr13q32 | 27 | 15 | 17377 | 1707 |
FARP1,TM9SF2,CLYBL,DNAJC3,IPO5,ZIC5,TMTC4,TNFSF13B,UBAC2,GPR180,ZIC2,TGDS,GPC6,DOCK9,HS6ST3 |
| 4.007e-09 | -19.34 | multicellular organismal process | biological process | GO:0032501 | 6701 | 754 | 17256 | 1658 |
ARHGAP26,DOC2A,THOC5,PDE1B,GRIK2,RECK,MCOLN3,STAT5B,CEBPA,CHAC1,KIAA1217,BCAN,EYA4,SKI,BAG3,TGFBR3,RAP2A,RAB26,TSHR,CPE,POU3F3,NKX2-1,MEIS2,SMAD9,DCC,WLS,GJB2,LRRK2,NFIA,HACD1,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,F12,ENPP1,WIPF3,ATP7B,ALDOA,ADRB1,TMOD2,INPP5F,TPM1,VASH2,MEF2C,SCN5A,GNG12,STOX2,ITGA6,BTBD9,BBS9,FOXG1,HPCAL4,CHN1,SYCP2,FRY,CACNB2,FLRT3,ZIC5,TOX,LOXL4,NCAM1,STXBP1,GFRA1,LRP12,CHRM3,ZNF385A,HMGCR,ENAM,BDNF,PNP,SPATA6,ARID5B,FHL2,FASN,RYR2,SMARCD3,CALCRL,PLS1,SHISA2,SNAP25,OR11H4,TAF4B,CLN5,SPATA7,TEX15,SH3GL2,ADAMTS3,CDH17,SELENOM,CLMN,HOXD13,SPRED3,CDH2,TRPC3,SHTN1,CSRP2,DOCK9,TFCP2L1,BTC,DNM3,ZNF516,PKP2,ADD2,NRXN1,LCP2,TXNRD3,EPB41L3,PLPP1,TLR3,GPRIN1,CHRNA5,DACT1,COL25A1,RTKN2,SYNGR3,ZNF365,DNAH5,MYT1,SNX10,PERP,SCN3A,DOCK8,FZD1,SSH3,MYLK3,ADM2,FZD4,NKX3-2,ADCY1,WNT11,DSP,ASPH,FGFR1,GJC1,IRS2,ENTPD1,CXCL10,WFS1,APELA,WWTR1,LAMB1,PAM,DBP,HOXB9,CGB2,SERINC5,FARP1,EDA2R,ROBO2,PLAG1,FZD8,BIK,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,COL27A1,NEO1,HMGCS1,LRRN1,MORN2,MYO6,NPTXR,ZFP36L2,FES,TRPM4,PDLIM7,B9D1,VEGFC,MN1,LZTS3,RAPGEF2,AK4,RACK1,SNTB1,HEG1,PTPRC,ID3,PCDHB7,AKT3,GNAO1,XBP1,BMP4,JHY,SHOX2,DOCK6,ATP2B4,FOXA1,BTRC,PHC1,TLL2,CACNG3,FGF13,LILRB1,ASS1,NDRG2,HDGFL3,NRN1,ITPR2,PLS3,RND2,KCNAB1,KCNN2,EOMES,HPS1,MARVELD2,ITGB3,MPPED2,TBC1D32,LIN7A,COL19A1,ETV1,TLR4,RAPGEF5,NEB,DBN1,CD55,KCNIP3,GCNT2,MARK1,ATF4,COL4A3,ANK2,NFE2L1,CR2,PLEKHA1,BATF,PLEKHB1,TSKU,DYRK1B,TCF7L1,KCNMB4,INSIG1,MAP2,GNB4,TNFRSF1A,AHNAK2,CIART,DLX2,NEUROG2,MLLT3,CHMP4C,PRKAA2,TYRO3,RGS16,RUNX2,UBASH3B,SORBS3,ZIC2,IL18R1,PGAP1,DOK5,SPIRE1,FHOD3,EFEMP1,RNF180,NUMBL,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,FRAS1,SMTN,LRP6,ADCY6,BNIP3,MED7,SLCO4C1,PAK1,FGFR4,DPYSL5,UNC5C,HOMER2,EFNA3,GPSM1,SLITRK5,MAFB,OBSCN,SDK1,BAIAP2,NEGR1,MAPKAPK2,KCNK15,GRIK4,MFSD2A,HEYL,CSF1,SEMA3A,SIX2,MME,SFN,PRKN,ID1,DOCK1,RBFOX2,OR51B4,NTRK3,SLC7A2,RADIL,PCLO,PPP1R9A,SEMA6A,CBLN1,CTNNA2,RIDA,TACC2,LHX6,MYO3B,BCL6,MYH15,SCN2A,ZNF488,SNAI2,GLI1,IGFBP3,INTU,EVL,CSN2,TMEM65,PRDM13,FGF12,ACO1,CHRNA6,VIM,RARRES2,JAM3,C4BPB,SMAD3,IFT81,NRG3,PTPRJ,PTK7,ITGA2,PTPRS,HGF,CTNND2,RETREG1,CNTN1,HEY1,TENM1,COL9A3,PCDH18,DYRK3,BMPR2,PAK5,APBB1,NLRP14,MCTP2,GABRG2,HBE1,PRDM8,PPP2R3A,ARHGAP44,FOXP2,MAP1A,FUT9,KCNMB3,TFAP2A,SGK1,SH3PXD2B,PCK2,SYK,SLC45A3,ATP2B1,PCSK6,CES3,DUSP1,MICAL2,FOXN3,CRIP2,PRICKLE1,FNDC3A,PALLD,ILDR2,MGMT,MKX,DKK1,EBF1,DDAH1,DOCK7,FAT4,FBN1,DLG2,MYRF,PAX9,CACNA2D1,ACVR1,LGR4,ATP8A1,LDLR,VAMP8,GATA3,ENAH,ADAMTS6,PRKCA,RAC3,DACH2,AARS,STK24,NCS1,TRPS1,TYMP,SLC22A18,CHRDL1,GSTM3,PACSIN1,PLTP,TBC1D8,NR6A1,SLC9C1,KLHL3,ACVR1C,MEF2B,AGO4,EFHC1,ACVR2B,SAV1,SFXN1,SPATA9,HLF,NCKAP1L,CCBE1,PLK2,BMP1,SERPINI1,SEMA3C,SPRY4,SPART,UNC5B,TANC2,NRP1,EFNB2,SEMA6B,LRFN5,MRC2,INPPL1,CELSR1,PTPRD,GABRB2,MLF1,SCN8A,DHCR24,OPHN1,SLC25A27,GTF2IRD1,SLC1A3,TNFRSF10C,APBA1,HERC6,TNFRSF19,CHD5,MYORG,MECOM,MCOLN2,ABLIM1,NAV1,SLC7A11,CNTN4,PDZD7,MYC,PRELID1,SREBF1,PRKG1,GRIP1,TSPAN12,COL9A2,GPR161,RIMS2,IGSF3,EPB41L5,PTCH2,DISC1,COL4A4,DCHS1,VLDLR,NSD2,NPC2,PLCB1,MMP15,DAGLA,PKN3,THBS4,CECR2,WDR19,MATN2,DYNC2LI1,MPP2,SFMBT1,DHCR7,ACSM3,EPHA3,NBL1,AMOTL1,PCSK1N,ST14,GPR65,PLXNA2,MSR1,OTX1,CHUK,DDR1,CCDC120,SPEG,ASNS,DAB2IP,PDE4D,SERPINH1,GATM,GAB2,SOX21,SHANK2,PREX1,NLGN4X,PRKCQ,CBY1,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,SNCA,HTR7,POPDC3,BEX3,PRKCB,ASIC1,CCNA1,MAP3K21,HPGD,KLF5,GRB10,BMPR1A,ATG5,MAPK10,CTTNBP2,STON2,COBL,MID1,WASF3,MYO1D,KIF5C,GABRR2,SELENOP,GDPD5,PHLDA2,ADGRB2,NEDD4,HOPX,KDM7A,LRRC55,IRX5,SOAT2,MGAT1,AFF2,GPR155,FIG4,DYNC2H1,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,SLC40A1,VAV3,PXN,GSTM2,TMEM126A,HOXA1,ZIC1,GPLD1,CEBPB,OR2T33,TERT,PCGF2,TUFT1,SVIL,GRIN2D,MYOM2,LRRK1,TNFRSF17,DDIT3,ATP1A3,EXPH5,MPZL3,UGT8,KIF5A,UGDH,JCHAIN,ABAT,CACNB4,RBM11,DNER,KREMEN1,HMCN1,F3,GSDME,EPCAM,LRRC6,GRHL1,DLX6,EPHB6,CTTN,OR2W3,IL1RAP,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,ATL1,GPM6A,CEMIP2,JPH1,YAP1,ROR1,EML1,GSN,GPRC5B,HPSE,NCAM2,OXTR,TNFSF4,PPARGC1A,APBA2,MAGI2,PCSK5,BCL11B,UST,FN1,OTOGL,BVES,SEC24D,CYP4V2,LAMC3,CHSY1,SATB1,PHGDH,SPINK5,ADGRG6,DDIT4,PCDHB14,EEF2,CA2,ZNF354A,EBF4,INAVA,NCEH1,BARX1,NOS3,PCDH10,CDH26,RAX,ATP5IF1,HBG2,SLITRK2,MSTN,SH2D2A,PRDM1,RIPOR2,ADGRB3,RAI14,HK2,EGFL7,NKX2-8,CREB3L2,CXCR5,SORBS1,ZSWIM5,CELSR3,IL15,PLEKHA5,ARHGAP22,HECW2,COL18A1,TDRKH,DOCK2,SP8,KCTD15,SETDB2,UNC13B,KAZN,ZNF521,ACVR2A,PROS1,POU2F2,MET,NTNG1,HSPA2,SEMA6C,PTPRU,PTPN6,AMIGO1,CD40,DOCK5,TTLL7,BATF3,WARS,BCL11A,ARMC4,MSC,RBPMS2,SOHLH2,DISP1,OR51B5,TNIK,ARHGEF11,LRP4,CMTM8,OVOL2,BMP6,NKX6-1,KCNJ4,SCN1B,GTSF1,PRKCD,STC2,EHD3,DSG2,KIAA0319,ACTA2,TRIM3,MTURN,RRAS2,TNFRSF11A,USP2,MSX1,KDM5B,CRIM1,NR4A1,SYBU,GRID1,MEI1,ZFPM2,TLR6,LRAT,LEPR,MAP1B,RERE,DPY19L2,EDA,PRCP,MAP2K6,CTSV,SLC7A5,NPHP1,MAP3K20,MMP16,ABCG1,SNPH |
| 4.042e-09 | -19.33 | SCGB1D1 (secretoglobin family 1D member 1) | protein interactions | 10648 | 73 | 26 | 17029 | 1718 |
SUSD3,TMEM67,MRC2,CCDC148,PTPRU,CNTNAP3,PLXNA2,SEL1L3,PGAP1,LEPR,CHST10,EPDR1,CACHD1,BCHE,ENTPD7,FRAS1,VWDE,ITGA2,SLC2A6,LRP6,MOXD1,MET,PLTP,CPE,LIFR,CACNA2D1 |
| 4.048e-09 | -19.32 | cell projection organization | biological process | GO:0030030 | 1115 | 166 | 17256 | 1658 |
UGT8,KIF5A,GATA3,HDGFL3,ENAH,PRKCA,RAC3,STK24,TUBB4A,LRRC6,DNAH6,RAP2A,TBC1D32,CTTN,PACSIN1,ETV1,SLIT2,NKX2-1,ATL1,GPM6A,ABCC4,DCC,LRRK2,FEZ1,PRKAR2B,PLEKHA1,ARHGEF26,TSKU,GSN,MAP2,NCKAP1L,NCAM2,SEMA3C,TPM1,NRP1,DNHD1,UNC5B,BCL11B,EFNB2,LRFN5,INPPL1,ITGA6,OPHN1,PHGDH,FOXG1,BBS9,TTC30B,DOK5,CHN1,ABLIM1,NUMBL,CNTN4,FRY,SEMA4F,IGF1R,PDZD7,FLRT3,PRKG1,GRIP1,NCAM1,STXBP1,GFRA1,LRP12,PAK1,DPYSL5,UNC5C,BDNF,DISC1,RHOQ,SLITRK2,SPATA6,VLDLR,EFNA3,SPATA13,SLITRK5,TTC30A,BAIAP2,SH3GL2,WDR19,MATN2,DYNC2LI1,CLMN,FNBP1L,NKX2-8,SEMA3A,SHTN1,EPHA3,NBL1,DNM3,TCTN2,RHOD,CELSR3,RBFOX2,PLXNA2,NRXN1,DDR1,PIBF1,PPP1R9A,SEMA6A,CTNNA2,EPB41L3,GPRIN1,CDC14B,COL25A1,DAB2IP,ZNF365,SNX10,DNAH5,NTNG1,SEMA6C,GAB2,INTU,EVL,TMEM67,TUBA1A,SHANK2,ADCY1,PRKCQ,CBY1,ATOH1,AMIGO1,JAM3,ARMC4,IRS2,IFT81,LAMB1,WWTR1,GRB10,KLF5,SEPT5,COBL,CTNND2,CNTN1,WASF3,TNIK,FARP1,ROBO2,APBB1,LRP4,KIF5C,EPHB1,GDPD5,NEDD4,NEO1,LRRC55,LRRN1,MAP1A,SCN1B,EHD3,SGK1,DYNC2H1,NPTXR,SEPT3,PDLIM7,B9D1,VAV3,RAPGEF2,RERE,MAP1B,DOCK7,TMEM237,FAT4,GNAO1,JHY,NPHP1,ATP1A3 |
| 4.245e-09 | -19.28 | GO_SYNAPSE | MSigDB lists | GO_SYNAPSE | 729 | 121 | 17377 | 1707 |
DOC2A,DMXL2,DNM3,SCAMP1,PRSS12,GRIK2,AKAP5,SYT12,RGS20,ADD2,KCTD12,ENAH,NRN1,CTBP2,CADM2,NRXN1,CANX,BCAN,PRR7,CACNB4,PCLO,CBLN1,PPP1R9A,NCS1,CTNNA2,EPB41L3,KCNN2,UNC13B,CHRNA5,DACT1,PPFIA2,LIN7A,MARCKS,CTTN,PACSIN1,TLN2,SYNGR3,CPE,MYRIP,GPM6A,CAP2,ANK2,SHANK2,LRRK2,DNAJC6,NLGN4X,CHRNA6,PRKAR2B,PRKCQ,SNCA,TRIM9,CAMK2N1,SEPT5,APBA2,MAGI2,CTTNBP2,STON2,LZTS1,CTNND2,MEF2C,SV2B,FARP1,SLC6A9,BMPR2,GABRB2,LRP4,EPS8,APBB1,OPHN1,CLSTN2,GABRG2,PSD3,COL4A5,GABRR2,P2RY1,SLC1A3,APBA1,KCNC4,PFN2,ARHGAP44,RGS17,KCNJ4,SEMA4F,FLRT3,LRP6,GRIP1,BNIP3,MPDZ,CADPS2,SEPT3,STXBP1,RIMS2,ATP2B1,CHRM3,DLGAP1,DISC1,SLC40A1,UNC5C,RAB3B,RAPGEF2,HOMER2,GRID1,RABAC1,SDK1,SNAP25,ARHGAP32,SNTB1,CPEB1,BAIAP2,MAP1B,HOMER3,GRIK4,ICA1,THBS4,PTPRN2,GRIN2D,DLG2,CDH2,MME,ATP1A3,SNPH |
| 4.339e-09 | -19.26 | GO_NEURON_DIFFERENTIATION | MSigDB lists | GO_NEURON_DIFFERENTIATION | 848 | 136 | 17377 | 1707 |
UGT8,KIF5A,MCOLN3,GATA3,ENAH,RAC3,PLS3,RTN1,EOMES,CTTN,PACSIN1,ETV1,SLIT2,NKX2-1,ATL1,GPM6A,DCC,LRRK2,FEZ1,TSKU,MAP2,SEMA3C,DLX2,UNC5B,NRP1,NEUROG2,MEF2C,EFNB2,BCL11B,LRFN5,RUNX2,PTPRD,GABRB2,OPHN1,SLC1A3,PHGDH,SPINK5,CHD5,DDIT4,CHN1,NUMBL,CNTN4,SEMA4F,FRY,PDZD7,GATA2,FLRT3,PRKG1,LRP6,GRIP1,NCAM1,STXBP1,DPYSL5,PAK1,BDNF,DISC1,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,PRDM1,CLN5,BAIAP2,THBS4,MATN2,CLMN,NKX2-8,SEMA3A,EPHA3,NBL1,ID1,CELSR3,RBFOX2,PLXNA2,NTRK3,NRXN1,PPP1R9A,CBLN1,SEMA6A,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,ZNF521,DAB2IP,NTNG1,SEMA6C,FZD1,EVL,FZD4,ADCY1,NLGN4X,WNT11,PRKCQ,SATB2,ATOH1,AMIGO1,JAM3,FGFR1,LAMB1,LIFR,COBL,CTNND2,CNTN1,FARP1,ROBO2,FZD8,LRP4,APBB1,KIF5C,EPHB1,GDPD5,NEDD4,PPP2R3A,NEO1,NKX6-1,LRRC55,LRRN1,SCN1B,SGK1,FIG4,DYNC2H1,RAPGEF2,MAP1B,RERE,CEBPB,ID3,DOCK7,FAT4,GNAO1,XBP1,BMP4,FOXA1,SNPH |
| 4.500e-09 | -19.22 | neck | COSMIC cancer mutations | neck | 1249 | 184 | 17385 | 1698 |
CACNG3,FGF13,PRSS12,ATP8A1,UGDH,PTPN21,MGAT5B,KIAA1217,DNER,HMCN1,LGI2,GRHL1,ZFYVE28,FAAH2,JAKMIP2,PCOLCE2,PACSIN1,PTPRE,THSD1,TLR4,SLIT2,DCC,CAP2,LRMP,JPH1,ZNF565,NFE2L1,CR2,TNS1,KCND3,FGF17,GPC6,SPNS1,TRIM9,TMEM132B,ENPP1,KCNMB4,SH3RF1,ITGBL1,NRP1,UNC5B,VASH2,NEUROG2,FRMD5,KCNV1,LRFN5,SCN5A,MOCOS,RUNX2,PTPRD,ELOVL7,PGAP1,DOK5,MCOLN2,CA2,ABCA5,PDE10A,ZIC5,STXBP1,GLIS1,RIMS2,CAND2,CHRM3,PTCH2,CDH26,GPR176,RNF170,SLC27A2,ARID5B,MGAT4B,KIAA1324L,SHISA2,SDK1,PLCB1,SLC46A3,KHDRBS2,TEX15,PLEKHH2,CSAG1,PKN3,ADAMTS3,MFSD2A,QPCTL,MPP2,CDH17,PTPRN2,TRPC3,CREB3L2,DMXL2,EPHA3,TCTN2,CFH,CELSR3,RBFOX2,HECW2,ADD2,PKP2,SLC7A2,DENND3,PIBF1,CDS1,COL22A1,MYO3B,FHIT,PROS1,MET,DNAH5,NTNG1,SCN3A,SUSD3,DPP10,FER,PHLDB2,SFXN4,SHANK2,PANK1,ADCY1,PREX1,NLGN4X,PRKCQ,DOCK5,DSP,FGFR1,ZNF711,IQCH,PTPRJ,LMLN,POPDC3,RNF217,PTK7,PTPRS,KLF5,HGF,DBP,MBOAT2,CTTNBP2,CTNND2,CNTN1,ROBO2,KLHL13,CD276,IPO5,MCTP2,TNFSF13B,CLSTN2,CBS,PRDM8,COL4A5,P2RY1,EPHB1,NEDD4,MAP1A,GAS2L3,STC2,SGK1,SLC6A15,SH3PXD2B,TNFRSF11A,ATP2B1,MN1,CARD6,ARAP2,LRRIQ1,ESRRG,PTPN13,ASAP3,GALNT14,LEPR,RERE,PTPRC,NSD1,DDAH1,ICA1,FAT4,TERT,FBN1,ACER2,MYOM2,ZNF474,GEM,MMP16,NPHP1,LARP1,TLL2 |
| 4.530e-09 | -19.21 | lung-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-squamous_cell_carcinoma | 15113 | 1549 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,RASA3,ATP11A,NSD1,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,IGFBP3,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,KCNMB3,TFAP2A,TSC22D1,SGK1,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,AGPAT4,PTPN13,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,PLAGL1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,BTC,ZNF516,DNM3,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,CD55,ABCC4,PLEKHA1,TCERG1L,NT5DC2,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,OPHN1,GTF2IRD1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,WASF3,ANO10,ANKRD13D,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,FAM107B,NCEH1,MORN4,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,TDRKH,UBTD2,DOCK2,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH |
| 4.619e-09 | -19.19 | skin-neck-malignant_melanoma | COSMIC cancer mutations | skin-neck-malignant_melanoma | 1241 | 183 | 17385 | 1698 |
CACNG3,FGF13,PRSS12,ATP8A1,UGDH,PTPN21,MGAT5B,KIAA1217,DNER,HMCN1,LGI2,GRHL1,ZFYVE28,FAAH2,JAKMIP2,PCOLCE2,PACSIN1,PTPRE,THSD1,TLR4,SLIT2,DCC,CAP2,LRMP,JPH1,ZNF565,NFE2L1,CR2,TNS1,KCND3,FGF17,GPC6,SPNS1,TRIM9,TMEM132B,ENPP1,KCNMB4,SH3RF1,ITGBL1,NRP1,UNC5B,VASH2,NEUROG2,FRMD5,KCNV1,LRFN5,SCN5A,MOCOS,RUNX2,PTPRD,ELOVL7,PGAP1,DOK5,MCOLN2,CA2,ABCA5,PDE10A,ZIC5,STXBP1,GLIS1,RIMS2,CAND2,CHRM3,PTCH2,CDH26,GPR176,RNF170,SLC27A2,ARID5B,MGAT4B,KIAA1324L,SHISA2,SDK1,PLCB1,SLC46A3,KHDRBS2,TEX15,PLEKHH2,CSAG1,PKN3,ADAMTS3,MFSD2A,QPCTL,MPP2,CDH17,PTPRN2,TRPC3,CREB3L2,DMXL2,EPHA3,TCTN2,CFH,CELSR3,RBFOX2,HECW2,ADD2,PKP2,SLC7A2,DENND3,PIBF1,CDS1,COL22A1,MYO3B,FHIT,PROS1,MET,DNAH5,NTNG1,SCN3A,SUSD3,DPP10,FER,PHLDB2,SFXN4,SHANK2,PANK1,ADCY1,PREX1,NLGN4X,PRKCQ,DOCK5,DSP,FGFR1,ZNF711,IQCH,PTPRJ,LMLN,POPDC3,RNF217,PTK7,PTPRS,KLF5,HGF,DBP,MBOAT2,CTTNBP2,CTNND2,CNTN1,ROBO2,KLHL13,CD276,IPO5,MCTP2,TNFSF13B,CLSTN2,CBS,PRDM8,COL4A5,P2RY1,EPHB1,NEDD4,MAP1A,GAS2L3,STC2,SGK1,SLC6A15,SH3PXD2B,TNFRSF11A,ATP2B1,MN1,CARD6,ARAP2,LRRIQ1,ESRRG,PTPN13,ASAP3,GALNT14,LEPR,RERE,PTPRC,NSD1,DDAH1,ICA1,FAT4,FBN1,ACER2,MYOM2,ZNF474,GEM,MMP16,NPHP1,LARP1,TLL2 |
| 4.700e-09 | -19.18 | bone-humerus-other-chondroblastoma | COSMIC cancer mutations | bone-humerus-other-chondroblastoma | 309 | 64 | 17385 | 1698 |
ARHGAP26,RHPN2,ENAH,DOCK2,HMCN1,FSTL5,FKBP9,PPFIA2,ZNF521,FHIT,PPP2R2B,PCOLCE2,TLN2,TLR4,TSHR,SNX10,SLIT2,KCNB2,GPM6A,EVL,KCNIP3,DCC,FGF12,RAB38,ZDHHC14,TTLL7,GPC6,KCNMB4,COBL,FARP1,WDFY4,TPD52L1,FHOD3,SLC35F1,CHN2,FRAS1,PRKG1,FMNL2,KIAA1211,HMGCR,DLGAP1,CRIM1,RNF170,ESRRG,COL4A4,CYTH3,GRID1,ST6GALNAC3,SDK1,ZFPM2,KHDRBS2,NAALADL2,CTIF,NEGR1,GPR37,BEX4,DDAH1,PLEKHH2,SH3GL2,PTPRN2,PLD1,TBC1D4,SEMA3A,XKR4 |
| 5.153e-09 | -19.08 | GSE22886_NAIVE_BCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_MONOCYTE_UP | 171 | 43 | 17377 | 1707 |
UST,FBXO4,MCTP2,MORC4,COBLL1,SEL1L3,DDR1,TBC1D30,NIPSNAP3B,TIAM2,SLC9A7,HOPX,TBC1D19,ABLIM1,SEMA4F,PAIP2B,BACE2,MCF2L,FRAS1,MARCH3,TSPAN13,SP140,PTPRCAP,MOXD1,RRAS2,SCN3A,ULBP1,BCL7A,GPM6A,CR2,TAF4B,SKAP1,DSP,BCL11A,BACH2,KIAA0355,PIK3C2B,SPRY4,TNFSF4,TTC39A,FNBP1L,NR3C2,PKIA |
| 5.250e-09 | -19.07 | MODULE_47 | MSigDB lists | MODULE_47 | 215 | 50 | 17377 | 1707 |
RGS16,SV2B,NBL1,MRC2,FN1,LMCD1,COL18A1,NRN1,GAS6,GAS1,CFHR1,SMTN,ZNF521,ACTA2,MARCKS,SERPINH1,MOXD1,PLTP,PRR16,VGLL4,SLIT2,CKAP4,PDGFRB,IGFBP3,CYP1B1,VAV3,COL6A2,GJB2,FGF12,C1R,VIM,TMEM47,RARRES2,PALLD,JAM3,FGFR1,EML1,MAP1B,ID3,PLAGL1,PMEPA1,FBN1,WWTR1,LAMB1,SH3BP4,RAB31,BMP1,P4HA1,SEMA3C,TPM1 |
| 5.410e-09 | -19.04 | regulation of neurogenesis | biological process | GO:0050767 | 732 | 119 | 17256 | 1658 |
EPHA3,PRKN,NBL1,ZSWIM5,DNM3,ID1,FGF13,LDLR,PLXNA2,GATA3,HECW2,NTRK3,RAC3,PPP1R9A,SEMA6A,NCS1,STK24,SKI,RND2,EOMES,RAP2A,BCL6,DAB2IP,CTTN,PACSIN1,ZNF488,ZNF365,SLIT2,IL1RAP,FZD1,DBN1,SSH3,FZD4,DCC,SHANK2,LRRK2,PREX1,YAP1,FEZ1,VIM,AMIGO1,ATOH1,FGFR1,NRG3,GPRC5B,MAP2,PLK2,PTK7,PTPRS,SEMA3C,SERPINI1,HGF,INPP5F,DLX2,BMPR1A,SPART,NRP1,MAGI2,COBL,CNTN1,MEF2C,BCL11B,UST,EFNB2,TNIK,FN1,ROBO2,BMPR2,PTPRD,PLAG1,LRP4,APBB1,GDPD5,FOXG1,BMP6,NEDD4,ARHGAP44,NKX6-1,CHN1,NUMBL,CNTN4,SEMA4F,GATA2,SCN1B,KIAA0319,ADCY6,GRIP1,FIG4,GFI1,SLC45A3,RIMS2,FES,PAK1,VEGFC,LZTS3,DISC1,BDNF,RAPGEF2,VLDLR,EFNA3,SMARCD3,SDK1,SNAP25,BAIAP2,MAP1B,NEGR1,DKK1,ID3,DOCK7,ADGRB3,TERT,HEYL,CSF1,BMP4,SHOX2,SEMA3A,CDH2,FOXA1,SHTN1 |
| 5.417e-09 | -19.03 | regulation of plasma membrane bounded cell projection organization | biological process | GO:0120035 | 629 | 106 | 17256 | 1658 |
EPHA3,PRKN,DNM3,ID1,ZSWIM5,FGF13,PLXNA2,HECW2,GATA3,NTRK3,TBC1D30,PPP1R9A,STK24,NCS1,TBC1D19,RND2,RAP2A,DAB2IP,CTTN,PACSIN1,ZNF365,SLIT2,IL1RAP,FZD1,TBC1D8,DBN1,FER,SSH3,GPM6A,EVL,DCC,FZD4,SHANK2,LRRK2,PREX1,FEZ1,VIM,AMIGO1,TBC1D16,FGFR1,MAP2,PLK2,PTK7,PTPRS,HGF,KLF5,SEMA3C,INPP5F,SERPINI1,ATG5,NRP1,SPART,MAGI2,COBL,CNTN1,MEF2C,EFNB2,UST,TENM1,TNIK,FN1,ROBO2,BMPR2,TBC1D1,PTPRD,APBB1,EPS8,LRP4,PFN2,ARHGAP44,NEDD4,NKX6-1,CHN1,SEMA4F,SCN1B,PRKCD,KIAA0319,GRIP1,ADCY6,FIG4,GFI1,FES,RIMS2,PAK1,BDNF,LZTS3,RHOQ,MYO10,RAPGEF2,VLDLR,PLS1,SNAP25,SDK1,BAIAP2,MAP1B,NEGR1,TBC1D2,RIPOR2,ADGRB3,DYNC2LI1,PLD1,FNBP1L,SEMA3A,CDH2,SHOX2,SHTN1 |
| 5.509e-09 | -19.02 | upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-larynx-carcinoma-squamous_cell_carcinoma | 1980 | 268 | 17385 | 1698 |
FAM171B,GXYLT2,PDE1B,GRIK2,CNTNAP3,ATP8A1,NPM1,CTBP2,CEBPA,BCAN,DACH2,PCDH7,EPDR1,DNAH6,PPFIA2,FAAH2,VWA5A,GLDC,GDAP1,DCC,LRRK2,LRMP,MEF2B,GPC6,ENPP1,MAP9,ALDOA,SEMA3C,ERCC5,INPP5F,ZBTB20,DSEL,TANC2,LPP,MEF2C,LRFN5,SCN5A,INPPL1,PTPRD,DYNC1I1,MCOLN2,SYCP2,FRY,CNTN4,PIK3AP1,SLC16A9,ST8SIA1,FMNL2,RIMS2,KCNQ3,MYO10,COL4A4,STAT4,DCHS1,ZNF605,KIAA1324L,RYR2,SNAP25,OR11H4,PLCB1,XKR9,TEX15,ADAMTS3,PKN3,LRRIQ3,SLFN5,TRPC3,EPHA3,DNM3,GALNT6,MSR1,COLEC10,NRXN1,TIAM2,SPEG,EPB41L3,NBEA,FAM133A,ZNF365,DNAH5,SNX10,KCNB2,SCN3A,DOCK8,FZD1,B3GALT1,KCNH5,PREX1,NLGN4X,SATB2,DSP,FGFR1,IRS2,PDLIM3,LAMB1,PAM,GRB10,CTTNBP2,NR3C2,COBL,HACE1,MYO1D,CCDC148,WDR17,ROBO2,PLAG1,KIF5C,PSD3,EPHB1,RGS17,AFF2,GHR,SGK3,SLC6A15,DYNC2H1,MYO6,ZFP36L2,MED12L,TRPM4,SLC40A1,SH3BP2,CACNA1E,RAPGEF2,HOXA1,PTPRC,NSD1,PCDHB7,TERT,SLCO5A1,MYOM2,CMPK2,SHOX2,LARP1,PHACTR3,MPZL3,LILRB1,ITPR2,SLC2A13,FAM13A,DNER,HMCN1,KREMEN1,FSTL5,FKBP9,KCNN2,ABI3BP,COL19A1,TLR4,OR2W3,NEB,ZNF391,GPM6A,JPH1,CR2,TMEM47,TCERG1L,TMEM132B,NCAM2,MAP2,GNB4,P4HA2,PIK3C2B,TC2N,RUNX2,STXBP5L,LAMC3,SETBP1,ZIC2,CD7,FHOD3,KIAA0895,EEF2,HS3ST5,FAM107B,LRP6,SLCO4C1,NOS3,PCDH10,SLITRK2,PARD3B,EDEM3,SLITRK5,OBSCN,B4GALNT3,KHDRBS2,KCNK15,KIAA0355,CSAG1,CSF1,FAT1,TESC,SIX2,DMXL2,CFH,CELSR3,XYLT1,ARHGAP22,COBLL1,COL18A1,HECW2,NTRK3,ZNF83,RNF24,SEZ6L2,RADIL,PCLO,DOCK2,PPP1R9A,SP8,COL22A1,UNC13B,PDZD8,REEP1,MYO3B,MYH15,SCN2A,MET,HSPA2,CTH,PRAME,TDRD3,FGF12,CD40,DOCK5,MAGEA12,RANBP2,PTPRJ,CNTN1,OR51B5,PCDH18,TNIK,PRSS16,NSUN6,GABRG2,CLSTN2,COL4A5,FSD1,FOXP2,SLC35F1,KCNJ4,TNFRSF11A,DLGAP1,LRRIQ1,HNF4G,NR4A1,GRID1,PRICKLE1,GALNT14,NAALADL2,ILDR2,DKK1,EBF1,GPR37,DPY19L2,FAT4,MYADM,L3MBTL4,FBN1,FMO4,THSD7B,DLG2,PAX9,THAP10,GEM,MMP16,IL9R,FILIP1,SNPH |
| 5.658e-09 | -18.99 | ductal_carcinoma | COSMIC cancer mutations | ductal_carcinoma | 16293 | 1642 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 6.027e-09 | -18.93 | GCM_MAPK10 | MSigDB lists | GCM_MAPK10 | 81 | 27 | 17377 | 1707 |
FAM171B,DNM3,KCNQ3,RAB6B,LRP4,DNAJC6,PRRG1,TTYH2,FEZ1,NDRG2,SLC1A3,PLEKHA1,NDFIP2,NCS1,PLEKHB1,PCDH7,IL17D,RNF141,CAMK2N1,EPB41L3,ARHGAP21,GPRC5B,ALDOC,SERPINI1,TMOD2,MAPK10,CTNND2 |
| 6.065e-09 | -18.92 | cytoplasmic region | cellular component | GO:0099568 | 468 | 84 | 18223 | 1724 |
GRIK2,RHOD,KIF5A,ABHD13,ITPR2,CANX,PCLO,PPP1R9A,HMCN1,SCIN,TUBB4A,RND2,KCNAB1,UNC13B,DNAH6,CNKSR3,RTKN2,MARCKS,CTTN,MYRIP,DNAH5,ENO1,GLI1,DBN1,FER,PHLDB2,WLS,DSTN,EXOC6B,CAP2,LRRK2,EFHC1,ASPH,GABARAPL1,SNCA,GNAI1,ARMC4,GSN,GYPC,WIPF3,MAP2,ATG5,SEPT5,DNHD1,CTTNBP2,COBL,RHOBTB1,STXBP6,EPS8,GPSM2,SPINK5,SPIRE1,NEDD4,FRY,MAP1A,DYNC2H1,IPCEF1,MYO6,SEPT3,RIMS2,USP2,RHOQ,PXN,MYO10,MPP1,PARD3B,CRIP2,SYBU,GPSM1,FERMT2,HIP1,PLS1,ARHGAP32,BAIAP2,SPATA7,PLEKHH2,MYADM,RND3,DYNC2LI1,RAI14,DLG2,CDH2,FNBP1L,KIF1B |
| 6.077e-09 | -18.92 | larynx | COSMIC cancer mutations | larynx | 1982 | 268 | 17385 | 1698 |
FAM171B,GXYLT2,PDE1B,GRIK2,CNTNAP3,ATP8A1,NPM1,CTBP2,CEBPA,BCAN,DACH2,PCDH7,EPDR1,DNAH6,PPFIA2,FAAH2,VWA5A,GLDC,GDAP1,DCC,LRRK2,LRMP,MEF2B,GPC6,ENPP1,MAP9,ALDOA,SEMA3C,ERCC5,INPP5F,ZBTB20,DSEL,TANC2,LPP,MEF2C,LRFN5,SCN5A,INPPL1,PTPRD,DYNC1I1,MCOLN2,SYCP2,FRY,CNTN4,PIK3AP1,SLC16A9,ST8SIA1,FMNL2,RIMS2,KCNQ3,MYO10,COL4A4,STAT4,DCHS1,ZNF605,KIAA1324L,RYR2,SNAP25,OR11H4,PLCB1,XKR9,TEX15,ADAMTS3,PKN3,LRRIQ3,SLFN5,TRPC3,EPHA3,DNM3,GALNT6,MSR1,COLEC10,NRXN1,TIAM2,SPEG,EPB41L3,NBEA,FAM133A,ZNF365,DNAH5,SNX10,KCNB2,SCN3A,DOCK8,FZD1,B3GALT1,KCNH5,PREX1,NLGN4X,SATB2,DSP,FGFR1,IRS2,PDLIM3,LAMB1,PAM,GRB10,CTTNBP2,NR3C2,COBL,HACE1,MYO1D,CCDC148,WDR17,ROBO2,PLAG1,KIF5C,PSD3,EPHB1,RGS17,AFF2,GHR,SGK3,SLC6A15,DYNC2H1,MYO6,ZFP36L2,MED12L,TRPM4,SLC40A1,SH3BP2,CACNA1E,RAPGEF2,HOXA1,PTPRC,NSD1,PCDHB7,TERT,SLCO5A1,MYOM2,CMPK2,SHOX2,LARP1,PHACTR3,MPZL3,LILRB1,ITPR2,SLC2A13,FAM13A,DNER,HMCN1,KREMEN1,FSTL5,FKBP9,KCNN2,ABI3BP,COL19A1,TLR4,OR2W3,NEB,ZNF391,GPM6A,JPH1,CR2,TMEM47,TCERG1L,TMEM132B,NCAM2,MAP2,GNB4,P4HA2,PIK3C2B,TC2N,RUNX2,STXBP5L,LAMC3,SETBP1,ZIC2,CD7,FHOD3,KIAA0895,EEF2,HS3ST5,FAM107B,LRP6,SLCO4C1,NOS3,PCDH10,SLITRK2,PARD3B,EDEM3,SLITRK5,OBSCN,B4GALNT3,KHDRBS2,KCNK15,KIAA0355,CSAG1,CSF1,FAT1,TESC,SIX2,DMXL2,CFH,CELSR3,XYLT1,ARHGAP22,COBLL1,COL18A1,HECW2,NTRK3,ZNF83,RNF24,SEZ6L2,RADIL,PCLO,DOCK2,PPP1R9A,SP8,COL22A1,UNC13B,PDZD8,REEP1,MYO3B,MYH15,SCN2A,MET,HSPA2,CTH,PRAME,TDRD3,FGF12,CD40,DOCK5,MAGEA12,RANBP2,PTPRJ,CNTN1,OR51B5,PCDH18,TNIK,PRSS16,NSUN6,GABRG2,CLSTN2,COL4A5,FSD1,FOXP2,SLC35F1,KCNJ4,TNFRSF11A,DLGAP1,LRRIQ1,HNF4G,NR4A1,GRID1,PRICKLE1,GALNT14,NAALADL2,ILDR2,DKK1,EBF1,GPR37,DPY19L2,FAT4,MYADM,L3MBTL4,FBN1,FMO4,THSD7B,DLG2,PAX9,THAP10,GEM,MMP16,IL9R,FILIP1,SNPH |
| 6.233e-09 | -18.89 | GO_NEURON_PROJECTION_DEVELOPMENT | MSigDB lists | GO_NEURON_PROJECTION_DEVELOPMENT | 526 | 94 | 17377 | 1707 |
EPHA3,NBL1,UGT8,CELSR3,RBFOX2,KIF5A,PLXNA2,GATA3,ENAH,NRXN1,RAC3,SEMA6A,PPP1R9A,CTNNA2,EPB41L3,GPRIN1,COL25A1,DAB2IP,CTTN,PACSIN1,ETV1,SLIT2,NTNG1,SEMA6C,NKX2-1,ATL1,GPM6A,EVL,DCC,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,JAM3,FGFR1,TSKU,MAP2,LAMB1,SEMA3C,UNC5B,NRP1,LIFR,COBL,CTNND2,CNTN1,EFNB2,BCL11B,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,EPHB1,PHGDH,GDPD5,NEDD4,NEO1,CHN1,NUMBL,LRRC55,CNTN4,SEMA4F,LRRN1,FRY,SCN1B,FLRT3,PRKG1,GRIP1,SGK1,NCAM1,STXBP1,PAK1,DPYSL5,BDNF,UNC5C,SLITRK2,RAPGEF2,VLDLR,EFNA3,SLITRK5,BAIAP2,MAP1B,RERE,DOCK7,GNAO1,THBS4,MATN2,CLMN,SEMA3A,NKX2-8 |
| 6.493e-09 | -18.85 | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | MSigDB lists | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | 549 | 97 | 17377 | 1707 |
DOC2A,PPP4R4,ACVR1,SCAMP1,CELSR3,HECW2,ADAMTS6,FAM13A,IKZF2,FAM110B,SEMA6A,FAM131B,TRPS1,GRHL1,ITGB3,JAKMIP2,PDE4D,SCN2A,SYNGR3,SCN3A,GLDC,MEIS2,CAPN5,BNIP3L,SATB2,TMEM47,RAB38,MFSD6,RNF44,FRK,TTLL7,HLF,KPNA3,SH3RF1,P4HA2,ADRB1,GRB10,TMOD2,ATG5,NRP1,MAGI2,LIFR,CTNND2,LPP,CARS,SEMA6B,STOX2,RUNX2,SLC6A9,ITGA6,PLAG1,ZCCHC24,SCN8A,JDP2,YPEL2,RASD1,PFN2,FOXG1,FHOD3,NEDD4,DDIT4,SLC35F1,GALNT1,CACNB2,KIAA0408,AFAP1L2,KLF9,NCAM1,ATP2B1,B4GALT6,PCDH10,UNC5C,SLC36A1,PTPN13,ESRRG,RAPGEF4,ARID5B,EFNA3,EDEM3,PRICKLE1,PHACTR2,PRDM1,FNDC3A,MBNL2,NAALADL2,GLCE,DAGLA,GALNT3,DEXI,DOCK7,FCHO2,ADAMTS3,KIAA0355,GNAO1,SEMA3A,RNF122,TLL2 |
| 6.510e-09 | -18.85 | LIM_MAMMARY_LUMINAL_MATURE_DN | MSigDB lists | LIM_MAMMARY_LUMINAL_MATURE_DN | 97 | 30 | 17377 | 1707 |
C2orf88,MEIS2,SORBS1,COL6A2,RECK,FOXN3,PRICKLE1,RASA3,KCTD12,VIM,SLC1A3,TMEM47,GAS6,FAM13A,TIAM2,BCL11A,IRS2,TGFBR3,FBXO32,GYPC,BACE2,EMILIN2,ZNF521,SLC6A15,SERPINH1,MOXD1,SNAI2,IGFBP3,FZD1,B4GALT6 |
| 6.834e-09 | -18.80 | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | MSigDB lists | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | 814 | 131 | 17377 | 1707 |
FAM171B,UGT8,ACSL1,CNTNAP3,DNAJC3,FHDC1,CA8,SLCO3A1,EPDR1,PCDH7,PLS3,PPP1R26,GRHL1,ZFYVE28,AKAP7,C1orf53,KCNS3,ATRNL1,TRPC1,PCOLCE2,PTPRE,IL1RAP,MEIS2,KLHL23,MSRB3,ACVR2B,CA13,EML1,KCNMB4,INSIG1,ENTPD7,CAB39L,INPP5F,SPRY4,VASH2,PRKAA2,EFNB2,STOX2,SEC24D,FBXO4,UBASH3B,RIMKLA,DHCR24,CYP4V2,ZNF215,SCD,GPSM2,PRRG4,RNF141,KIAA1958,OTUD1,IGF1R,SLC7A11,ZIC5,CADPS2,LIMCH1,SAMD13,NCEH1,AGL,CKAP4,CHSY3,FADS1,BTNL9,SPATA13,TMTC4,SLC46A3,GPR19,SH3BP4,OSBPL6,TFCP2L1,BTC,ID1,IL15,GALNT12,LRRCC1,COBLL1,KCTD12,TMEM170B,SLC7A2,KBTBD11,SLC19A2,KCTD15,IDI1,REEP1,ZDHHC23,ACVR2A,RTKN2,GULP1,WWC2,SNX10,HSPA2,GATM,PERP,FZD1,GAB2,ALG10B,CTH,FZD4,SLC39A8,SATB2,FBXO36,ASPH,DCBLD2,LMLN,PDLIM3,ZNF704,HS3ST3B1,HOXB9,ZNF701,MXI1,BMPR2,C1QTNF3,EPS8,TNFSF13B,KIF5C,GPR180,NDFIP2,RASSF8,HMGCS1,GAS2L3,NPTXR,B4GALT6,RAB3B,PRICKLE1,GPR137C,GPR37,TRIB3,FBN1,UACA,CMPK2,FOXA1 |
| 7.060e-09 | -18.77 | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-squamous_cell_carcinoma | 7133 | 807 | 17385 | 1698 |
DOC2A,FLVCR2,PDE1B,GRIK2,AASS,RECK,DNAJC3,MCOLN3,NPM1,STAT5B,CTBP2,CEBPA,BCAN,DOCK3,KIAA1217,SNX9,EYA4,NOS1AP,SKI,EPDR1,TXNDC5,TGFBR3,DNAH6,PPFIA2,FAAH2,RAP2A,RAB26,TMED9,PPP2R2B,TMEM37,COG3,KLHL29,TSHR,POU3F3,NKX2-1,DCC,TGFA,GJB2,LRRK2,MSRB3,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,ADRB1,ERCC5,ZBTB20,DNHD1,TMEFF2,VASH2,CRYL1,MEF2C,SCN5A,LATS2,TMEM63C,STOX2,CYP2J2,ITGA6,SLC36A4,BTBD9,FOXG1,BBS9,CHN1,SYCP2,FRY,APLF,FLRT3,ZIC5,SRGAP1,LMAN2,ALPK1,FAM84B,LOXL4,DENND1C,FIGN,NCAM1,ZNF518B,TSPAN9,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,KCNQ3,STAT4,ARID5B,FASN,RYR2,HIP1,PLS1,SNAP25,ZBBX,TEX15,TMCO3,GSTO2,SH3GL2,EMILIN2,CLMN,CDH2,DOCK9,BTC,NUDT10,DNM3,ZNF516,GALNT12,FAM131C,GALNT6,LRRCC1,ABHD13,RGS20,ADD2,IL13RA1,GRK6,LCP2,NRXN1,SLC19A2,CDS1,GPR15,RNF150,TLR3,GPRIN1,CNKSR3,COL25A1,DACT1,MAGEA3,RTKN2,JAKMIP3,DNAH5,MYT1,KIAA1549,KCNB2,SCN3A,FZD1,C3orf67,SSH3,MYLK3,COL6A2,GAPDH,RNF145,NECAB1,EBPL,PFKFB2,KCNH5,TRAM1L1,ADCY1,RAB38,TTC28,DSP,ASPH,FGFR1,ENTPD1,IQCH,LAMB1,PAM,PLEKHG1,RCN3,FAM149A,DBP,LRRC27,RAB30,TMEM132C,WDR17,ROBO2,IPO5,UBAC2,NKAIN2,CBS,SLC12A6,P2RY1,PKN1,EPHB1,ZNF219,COL27A1,LRRN1,GAS2L3,MYO6,MED12L,PARP9,PDLIM7,TRPM4,MN1,BCL7A,CLYBL,MCF2L2,RAPGEF2,RASA3,SNTB1,GALNT3,PTPRC,TRIB3,NSD1,PCDHB7,PLOD2,PLPPR2,OSBPL5,SLCO5A1,NEK11,PIP5KL1,CMPK2,DOCK6,DCBLD1,CRISPLD1,TPT1,PHACTR3,FAM227A,TRIM16,SYT12,FHDC1,LMCD1,NDRG2,LILRB1,MGAT5B,ITPR2,FAM13A,NOVA1,FSTL5,RUFY4,CPNE2,RPS6KA2,TM9SF2,EOMES,CPVL,KCNAB1,KCNN2,TMEM86A,ITGB3,MPPED2,COL19A1,JAKMIP2,KIAA1614,TLN2,TMEM132E,TLR4,ETV1,NEB,ITGB7,MARK1,CD55,KCNIP3,COL4A3,SPOCD1,ANK2,GDPD1,CR2,BATF,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,MAP2,GNB4,ERN1,TIGD4,TNFRSF1A,PIK3C2B,TC2N,HS6ST3,LONRF1,PRKAA2,KCNV1,RUNX2,STXBP5L,ITPRIP,SETBP1,SORBS3,PFN2,MLC1,IL18R1,PGAP1,SPIRE1,FHOD3,RNF180,NUMBL,ZBTB38,IGF1R,ABCA5,ZNF440,FRAS1,PDE10A,SAMD11,HS3ST5,LRP6,ADCY6,MED7,SLCO4C1,FAR2,PTPRCAP,PAK1,FGFR4,CHSY3,DPYSL5,SLC27A2,RNF170,MGAT4B,GPSM1,TMTC4,TCEA3,SPATA13,PPFIA4,OBSCN,SLITRK5,SDK1,KHDRBS2,TEX9,LDHD,BAIAP2,TBC1D2,NAP1L5,MAPKAPK2,KCNK15,HEYL,MFSD2A,PLD1,SEMA3A,RNF122,MME,SIX2,AVPI1,CFH,DOCK1,XYLT1,NTRK3,OR51B4,FAM198B,LPIN3,SEZ6L2,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,CYP26A1,TBC1D19,IDI1,SLC22A17,TACC2,ZDHHC6,LHX6,MYO3B,BCL6,ZDHHC23,MYH15,CLVS2,SCN2A,FAM78B,CTH,GLI1,INTU,TMEM67,CSN2,TDRD3,THSD4,RNF125,VIM,RARRES2,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,ITGA2,ABI3,KCNG1,PTPRS,SEPT5,MBOAT2,ZNF701,CTNND2,CNTN1,MAN2B2,COL9A3,IL32,BMPR2,GRB14,RUSC2,APBB1,MCTP2,NLRP14,RASD1,PPP2R3A,ARHGAP44,SLC35F1,MAP1A,FUT9,GTF2F2,TSC22D1,SH3PXD2B,PCK2,SYK,KIAA1211,CES3,DUSP1,DLGAP1,MICAL2,LRRIQ1,NUAK2,FERMT2,PRICKLE1,PALLD,SMPDL3B,HOMER3,CD37,DOCK7,FAT4,FBN1,ZNF808,DLG2,ZNF474,PAX9,SLC1A5,TBC1D4,KIF1B,CACNA2D1,FILIP1,ZNF235,FAM171B,MYCBP2,CGN,PPP4R4,LGR4,ATP8A1,LDLR,PPFIBP2,ENAH,PRKCA,DACH2,TRPS1,CFHR1,GSTM3,ATRNL1,BEND4,MAGEA6,VWA5A,THSD1,TBC1D8,GLDC,EML6,DCDC1,ACVR1C,KLHL3,FAM84A,KLHL4,DEPTOR,TNS1,ARHGEF26,GPC6,GNAI1,AHRR,SH3RF1,ENPP6,ENTPD7,RASGRF2,CCBE1,SEMA3C,DSEL,TANC2,UNC5B,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,CELSR1,PTPRD,ZHX3,TBC1D1,SCN8A,ST6GAL1,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,LRRC49,ISYNA1,TNFRSF10C,WDFY4,CHD5,MECOM,MTUS1,MCOLN2,ABLIM1,GBGT1,RALGPS2,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,SREBF1,PRKG1,CPXM2,SLC16A9,PRR16,FAM155A,COL9A2,RIMS2,IGSF3,EPB41L5,PTCH2,DISC1,QSOX1,TBC1D8B,COL4A4,VLDLR,RAPGEF4,DCHS1,KIAA1324L,TTYH2,TTC30A,NPC2,CCDC85A,CDC42BPA,PLCB1,TMEM74,MMP15,DAGLA,PLEKHH2,CECR2,LRRIQ3,MATN2,MPP2,SQLE,IQSEC2,SMYD3,AMPD1,ACSM3,EPHA3,NBL1,TBKBP1,AMOTL1,ELOVL4,ST14,CCDC110,ZNF311,PLXNA2,OTX1,MSR1,CHUK,DDR1,COL14A1,ZFYVE9,TIAM2,NELL2,SPEG,ASNS,ZNF438,NBEA,NAP1L3,GAB2,B3GALT1,SOX21,PREX1,NLGN4X,ATOH1,TBC1D16,HTR7,IKZF3,KLF5,CTTNBP2,NR3C2,PURG,HACE1,DENND5B,MYO1D,ANKRD13D,ATP9A,EPS8,PRSS35,CCNJL,KIF5C,ARL2,GPR180,GABRR2,RGS7,NEDD4,RASSF8,MGAT1,AFF2,RALGAPA2,DYNC2H1,TBC1D9,ERRFI1,GFI1,SEPT3,VAV3,SLC40A1,ALDH2,ARAP2,SH3BP2,SYNPO2,CACNA1E,PTPN13,GUCY1A2,GPR137C,ZIC1,TERT,NUTM2A,MCC,SVIL,PGM2L1,GRIN2D,MYOM2,OCLN,SLC43A1,ATP1A3,MVK,HEBP1,PTPN21,C20orf194,SLC2A13,ABAT,RBM11,KREMEN1,HMCN1,CHST10,RTN1,LGI2,CYP51A1,ADPRHL1,ARHGEF10L,PPM1E,SIPA1L2,LRRC6,AKAP7,ANKFN1,TRPC1,SLC2A12,CTTN,PCOLCE2,MYRIP,FANK1,OR2W3,IL1RAP,SLIT2,PDGFRB,RASGRP1,TNK2,GPM6A,SESN2,JPH1,ROR1,SGK2,RNF44,EML1,TMEM132B,GSN,GPRC5B,NCAM2,FAM114A2,CCDC169,MAGI2,PCSK5,GPR63,SV2B,MOCOS,ZNF395,FN1,RHOBTB1,SEC24D,RIMKLA,LAMC3,ATP6V1E2,FAM81A,SPINK5,PHGDH,SATB1,CD7,PCDHB14,EEF2,LIMCH1,CAND2,GPR176,PCDH10,RAX,IL17RD,PODXL2,SLITRK2,PARD3B,GSTM4,SDC3,WWC1,PRDM1,B4GALNT3,STEAP1,GLCE,KIAA0355,FCHO2,NCR3LG1,FAT1,RAI14,TMEM117,NXPH4,PTPRN2,NKX2-8,XKR4,CREB3L2,CXCR5,DMXL2,EML5,ZSWIM5,NEK10,SORBS1,CELSR3,PLEKHA5,HECW2,MORC4,COL18A1,BCL6B,TDRKH,PIBF1,DOCK2,SCIN,COL22A1,KCTD15,PDZD8,UNC13B,SETDB2,KAZN,RPS6KL1,PPFIBP1,ZNF521,MAP7,ACVR2A,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,TMEM120B,ZNF460,HSPA2,PRAME,PHLDB2,SLC39A8,PTPN6,TES,MVD,C3orf52,AMIGO1,SYNJ2BP,TTLL7,TPK1,ZNF569,ARMC4,LMLN,TMPRSS9,CYP2U1,RNF130,PSPH,MAST1,OR51B5,TNIK,CLGN,TSPAN15,ARL15,LRP4,SSX1,CLSTN2,COL4A5,CUEDC2,SEL1L3,BMP6,KCNJ4,GTSF1,PRKCD,DSG2,STC2,KIAA0319,MARCH3,IQGAP3,RRAS2,RIN2,CARD6,HNF4G,CRIM1,NR4A1,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,ZFPM2,GALNT14,TLR6,NAALADL2,MAP1B,RERE,DPY19L2,ICA1,MPP7,THSD7B,MMP16 |
| 7.139e-09 | -18.76 | tube development | biological process | GO:0035295 | 800 | 127 | 17256 | 1658 |
AMOTL1,ACVR1,ID1,LGR4,ST14,ARHGAP22,PLXNA2,GATA3,ASS1,COL18A1,CEBPA,PRKCA,DDR1,SKI,EPCAM,RIDA,TYMP,TGFBR3,SETDB2,DACT1,ITGB3,TBC1D32,DAB2IP,MET,SLIT2,POU3F3,PRKACB,PDGFRB,GLI1,NKX2-1,CYP1B1,FZD1,INTU,SMAD9,CEMIP2,KLHL3,FZD4,ADM2,NKX3-2,NFIA,YAP1,WNT11,ACVR2B,RARRES2,SAV1,JAM3,FGFR1,WARS,GJC1,SMAD3,HPSE,CCBE1,PTK7,APELA,RBPMS2,HPGD,KLF5,SEMA3C,OXTR,BMPR1A,UNC5B,NRP1,COBL,MEF2C,HEY1,PCSK5,EFNB2,CELSR1,BMPR2,ROBO2,FN1,ITGA6,FZD8,OVOL2,SLC12A6,EPHB1,PHGDH,FOXP2,GATA2,MYC,SREBF1,LRP6,TSPAN12,LOXL4,ERRFI1,SMAD6,SPRY2,SYK,NOS3,FGFR4,VEGFC,PAK1,EPB41L5,MICAL2,ATP5IF1,VAV3,KDM5B,SH2D2A,NR4A1,DCHS1,RYR2,CALCRL,PRICKLE1,PRDM1,ZFPM2,HOXA1,LEPR,GPLD1,HEG1,FAT4,EDA,PRCP,CECR2,CSF1,HEYL,WDR19,XBP1,EGFL7,HOXD13,BMP4,DHCR7,CDH2,NKX2-8,SHOX2,FOXA1,BTRC,SIX2 |
| 7.227e-09 | -18.75 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | 424 | 80 | 17377 | 1707 |
ACSL1,TTC39B,FLVCR2,FGF13,ATP8A1,UGDH,MYO1B,VAMP8,PPFIBP2,COBLL1,IL13RA1,FAM198B,IKZF2,KREMEN1,TBC1D30,CDS1,ZNF827,REEP1,ZDHHC23,RAB27B,HSPA2,PHLDB2,CD55,FZD4,WLS,SHANK2,FGF12,MFSD6,EML1,ENPP1,GSN,PTPRJ,NCAM2,PLK2,GPR160,ZNF704,GRB10,CAB39L,TC2N,CTNND2,EFNB2,BIK,DHCR24,PSD3,RASL11B,RASD1,INPP1,NIPSNAP3B,SPIRE1,MTUS1,SYCP2,KIAA1671,GATA2,FUT9,PRICKLE2,TSPAN13,LIMCH1,FAM84B,KLF9,NCEH1,ATP2B1,IGSF3,RIN2,MID2,PTPN13,ARID5B,LITAF,PDE8A,C3orf70,MBNL2,BEX4,GALNT3,TMCO3,TRIB3,ICA1,NACC2,SH3BP4,SMYD3,FILIP1,STOM |
| 7.325e-09 | -18.73 | GO_REGULATION_OF_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_CELL_DIFFERENTIATION | 1419 | 204 | 17377 | 1707 |
ACVR1,TRIM16,FGF13,GATA3,LILRB1,CEBPA,STAT5B,PRKCA,RAC3,STK24,NCS1,TRPS1,SKI,RND2,EOMES,ITGB3,RAP2A,CTTN,PACSIN1,TLR4,SLIT2,RASGRP1,NKX2-1,DBN1,MEIS2,GCNT2,DCC,LRRK2,YAP1,FEZ1,ACVR2B,SAV1,PLEKHB1,ENPP1,GPRC5B,INSIG1,NCKAP1L,PLK2,TNFRSF1A,SEMA3C,INPP5F,DLX2,NRP1,TNFSF4,MAGI2,LZTS1,MEF2C,UST,BCL11B,EFNB2,SEMA6B,RUNX2,LGALS3,FN1,ZHX3,PTPRD,JDP2,ST6GAL1,UBASH3B,CHADL,SPINK5,CHN1,EFEMP1,NUMBL,CA2,CNTN4,SEMA4F,ABCA5,GATA2,MYC,C1QL4,PRELID1,ADCY6,RIMS2,ZNF385A,PTCH2,EPB41L5,FADS1,BDNF,DISC1,PNP,MSTN,VLDLR,SMARCD3,MAFB,PRDM1,SDK1,SNAP25,PLCB1,CPEB1,BAIAP2,NEGR1,HEYL,CSF1,CDH2,SEMA3A,TESC,SFN,SIX2,EPHA3,NBL1,BTC,DNM3,ID1,IL15,AKAP5,RBFOX2,PLXNA2,MSR1,PKP2,BCL6B,NTRK3,PPP1R9A,SEMA6A,CTNNA2,SCIN,CD53,TLR3,BCL6,ACVR2A,DAB2IP,MARCKS,ZNF488,SEMA6C,SNAI2,CTH,FZD1,GLI1,IGFBP3,SSH3,PRAME,PHLDB2,MYLK3,NKX3-2,PTPN6,PREX1,VIM,AMIGO1,ATOH1,RARRES2,FGFR1,BCL11A,SMAD3,CXCL10,NRG3,IKZF3,GBP1,PTK7,WWTR1,KLF5,HGF,BMPR1A,COBL,HEY1,CNTN1,TNIK,ROBO2,BMPR2,CD276,PLAG1,LRP4,APBB1,OVOL2,GAS6,GDPD5,BMP6,NEDD4,HOPX,NKX6-1,SCN1B,BHLHA15,KIAA0319,TFAP2A,SGK1,SH3PXD2B,FIG4,ERRFI1,GFI1,SPRY2,ZFP36L2,SLC45A3,SYK,FES,TRPM4,PDLIM7,VEGFC,MSX1,RAPGEF2,PRICKLE1,ZFPM2,MAP1B,DKK1,CEBPB,ID3,TRIB3,DOCK7,MYADM,FAT4,XBP1,BMP4,SHOX2,FOXA1,DDIT3,ABCG1 |
| 7.384e-09 | -18.72 | GO_CELL_PROJECTION_ORGANIZATION | MSigDB lists | GO_CELL_PROJECTION_ORGANIZATION | 847 | 135 | 17377 | 1707 |
UGT8,KIF5A,GATA3,ENAH,RAC3,LRRC6,RAP2A,CTTN,PACSIN1,ETV1,SLIT2,NKX2-1,ATL1,GPM6A,ABCC4,DCC,LRRK2,FEZ1,PLEKHA1,ARHGEF26,TSKU,GSN,MAP2,SEMA3C,UNC5B,NRP1,TPM1,EFNB2,BCL11B,LRFN5,INPPL1,ITGA6,OPHN1,PHGDH,BBS9,TTC30B,CHN1,NUMBL,ABLIM1,CNTN4,SEMA4F,FRY,PDZD7,FLRT3,PRKG1,GRIP1,NCAM1,STXBP1,DPYSL5,PAK1,BDNF,DISC1,UNC5C,SLITRK2,SPATA6,VLDLR,EFNA3,SPATA13,TTC30A,SLITRK5,BAIAP2,THBS4,WDR19,MATN2,DYNC2LI1,CLMN,FNBP1L,NKX2-8,SEMA3A,EPHA3,NBL1,DNM3,TCTN2,CELSR3,RHOD,RBFOX2,PLXNA2,NRXN1,PIBF1,PPP1R9A,SEMA6A,CTNNA2,EPB41L3,GPRIN1,COL25A1,DAB2IP,DNAH5,SNX10,NTNG1,SEMA6C,INTU,EVL,TMEM67,ADCY1,PRKCQ,ATOH1,AMIGO1,JAM3,FGFR1,ARMC4,IFT81,WWTR1,LAMB1,KLF5,LIFR,COBL,CTNND2,CNTN1,TNIK,WASF3,FARP1,ROBO2,LRP4,APBB1,KIF5C,EPHB1,GDPD5,NEDD4,NEO1,LRRC55,LRRN1,SCN1B,EHD3,SGK1,DYNC2H1,B9D1,VAV3,RAPGEF2,MAP1B,RERE,DOCK7,FAT4,TMEM237,GNAO1,NPHP1 |
| 7.942e-09 | -18.65 | axon | cellular component | GO:0030424 | 540 | 93 | 18223 | 1724 |
DNM3,FGF13,GRIK2,PRSS12,C4A,NDRG2,NTRK3,CADM2,CANX,KIF21B,RAC3,PPP1R9A,SEMA6A,CTNNA2,TIAM2,NCS1,CCDC120,TUBB4A,EPB41L3,GPRIN1,KCNAB1,UNC13B,ADGRL1,DAB2IP,CTTN,SCN2A,PACSIN1,DBN1,ATL1,GPM6A,KCNIP3,GARS,DCC,SHANK2,LRRK2,PREX1,FEZ1,ROR1,AMIGO1,CD40,SNCA,MAP2,NCAM2,ITGA2,MAP9,RGS10,PTPRS,INPP5F,TMOD2,NRP1,COBL,PRKAA2,MYO1D,NECAB2,ROBO2,BACE1,SCN8A,APBB1,EPS8,BLVRB,OPHN1,KIF5C,GABRG2,EPHB1,KCNC4,GDPD5,PFN2,NAV1,MAP1A,IGF1R,CNTN4,CA2,SCN1B,FLRT3,NPTXR,STXBP1,CHRM3,PAK1,BDNF,KCNQ3,SYBU,SNAP25,PALLD,MAP1B,DAGLA,DOCK7,PTPRN2,DLG2,SEMA3A,KIF1B,SHTN1,MME,ATP1A3 |
| 8.133e-09 | -18.63 | regulation of transport | biological process | GO:0051049 | 1788 | 242 | 17256 | 1658 |
DOC2A,EXPH5,CACNG3,LGR4,TRIM16,SYT12,ATP8A1,LDLR,VAMP8,LILRB1,GATA3,ITPR2,ABAT,SYT14,PRKCA,CACNB4,NCS1,NOS1AP,ADPRHL1,BAG3,KCNAB1,KCNN2,SEC16B,TCAF2,PMAIP1,ITGB3,RAB26,KCNS3,TRPC1,TMEM37,PACSIN1,MYRIP,TLR4,PLTP,IL1RAP,RASGRP1,PDGFRB,TBC1D8,TNK2,KCNIP3,ATF4,ACVR1C,WLS,ANK2,JPH1,LRRK2,DNAJC6,BNIP3L,FEZ1,KCND3,SGK2,SERGEF,TRIM9,ENPP1,KCNMB4,INSIG1,NCKAP1L,BBC3,INPP5F,OXTR,NRP1,TNFSF4,PPARGC1A,MAGI2,TC2N,MEF2C,KCNV1,SCN5A,FN1,STXBP5L,LGALS3,TBC1D1,BVES,STXBP6,SCN8A,UBASH3B,OPHN1,SLC25A27,BTBD9,PFN2,MLC1,GAS1,CA2,GATA2,CACNB2,PRELID1,SREBF1,LMAN2,CADPS2,STXBP1,RIMS2,NOS3,HMGCR,PAK1,ATP5IF1,RHOQ,KCNQ3,TBC1D8B,HOMER2,RAPGEF4,PACSIN3,RYR2,WWC1,HIP1,SNAP25,TBC1D2,KCNK15,SH3GL2,HK2,TRPC3,CDH2,TESC,SFN,EPHA3,PRKN,DNM3,SORBS1,C4A,HECW2,PKP2,CHUK,NRXN1,PCLO,TBC1D30,PPP1R9A,DOCK2,SCIN,UNC13B,KMO,CNKSR3,REEP1,MARCKS,PDE4D,SCN2A,RAB27B,SYNGR3,HSPA2,KCNB2,SCN3A,GAB2,ALG10B,DPP10,FER,GAPDH,CSN2,PFKFB2,PTPN6,KCNH5,SHANK2,FGF12,CHRNA6,GSTO1,ATP1B1,RARRES2,SYNJ2BP,AMIGO1,CD40,TBC1D16,FGFR1,C4BPB,SNCA,IRS2,SMAD3,CXCL10,PRKCB,GBP1,APELA,WFS1,KCNG1,ITGA2,ASIC1,PAM,GRB10,DISP1,ATG5,SEPT5,STON2,CNTN1,TENM1,NECAB2,C1QTNF3,APBB1,IPO5,UBAC2,ARL2,NKAIN2,GAS6,P2RY1,NDFIP2,KCNC4,BMP6,NEDD4,MCU,NKX6-1,RAB11FIP5,KCNJ4,LRRC55,SCN1B,PRKCD,EHD3,STC2,SGK3,SGK1,PRKG2,TSPAN13,PCK2,MYO6,TBC1D9,TNFRSF11A,SYK,FES,TRPM4,VEGFC,GSTM2,RAB3B,KDM5B,CACNA1E,SYBU,CTTNBP2NL,RACK1,TLR6,LRAT,ZIC1,HOMER3,MAP1B,DKK1,GPLD1,TRIB3,FGR,ICA1,TERT,MAP2K6,GNAO1,XBP1,BMP4,GEM,TBC1D4,ATP2B4,CACNA2D1,PKIA,ABCG1,STOM |
| 8.508e-09 | -18.58 | HOELZEL_NF1_TARGETS_DN | MSigDB lists | HOELZEL_NF1_TARGETS_DN | 98 | 30 | 17377 | 1707 |
PHACTR3,PCDH18,BDNF,LATS2,NECAB2,FN1,ROBO2,ZNF395,FAM124A,AASS,TES,SLC39A8,JDP2,DCHS1,ADCY1,GATA3,PRICKLE1,NTRK3,SATB1,LEPR,HMCN1,BCL11A,LRRN1,DLX6,MATN2,ARHGAP28,SLC16A9,HRK,ST8SIA1,MMP16 |
| 9.318e-09 | -18.49 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | 168 | 42 | 17377 | 1707 |
ZNF516,KLHL13,CCDC110,PLAG1,ITGA6,FAM117B,SLC12A6,PRKCA,PHGDH,SATB1,CD7,RBM11,NUDT12,KBTBD11,DDR1,AARS,ABLIM1,TECPR1,IGF1R,DACT1,SREBF1,NBEA,PRICKLE2,IPCEF1,VNN2,CD55,PDK1,KLHL3,MPP1,BNIP3L,TAF4B,TTC28,CENPV,BACH2,IGIP,RGS10,DNHD1,APBA2,MLLT3,SLC16A10,SNPH,PCSK5 |
| 9.334e-09 | -18.49 | actin filament-based process | biological process | GO:0030029 | 534 | 93 | 17256 | 1658 |
ARHGAP26,AMOTL1,SORBS1,TMSB15A,RHOD,GPR65,MYO1B,COBLL1,PKP2,ADD2,RAC3,PPP1R9A,DOCK2,PLS3,SCIN,ARHGEF10L,RND2,EPB41L3,KCNN2,RAP2A,BCL6,POF1B,RTKN2,MARCKS,CTTN,PACSIN1,MYRIP,NEB,PDGFRB,DBN1,FER,EVL,MYLK3,CAP2,DSTN,ANK2,FGF12,PREX1,VIM,KCND3,GJC1,GSN,WIPF3,NCKAP1L,PTK7,ALDOA,TMOD2,TPM1,NRP1,COBL,FRMD5,WASF3,TNIK,SCN5A,INPPL1,ARHGEF11,PAK5,RHOBTB1,EPS8,OPHN1,SORBS3,PFN2,SPIRE1,FHOD3,FRY,SCN1B,CACNB2,GAS2L3,PRKG1,LIMCH1,MYO6,FMNL2,EPB41L5,PAK1,PDLIM7,MICAL2,RHOQ,NUAK2,HIP1,OBSCN,RYR2,PLS1,CDC42BPA,PALLD,BAIAP2,RND3,FAT1,MYOM2,IQSEC2,FNBP1L,NPHP1,SHTN1,CACNA2D1 |
| 9.524e-09 | -18.47 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP | 162 | 41 | 17377 | 1707 |
EXPH5,ZNF516,KLHL13,PLAG1,ITGA6,APBB1,RHPN2,TMEM170B,SATB1,PHGDH,NUDT12,DDR1,SNX9,ABLIM1,IGF1R,SREBF1,NBEA,CADPS2,ALG10B,CD55,PDK1,NPM3,MPP1,BNIP3L,TAF4B,TTC28,CENPV,METAP1D,GNAI1,LMLN,BACH2,GPRC5B,MPP7,IGIP,GPR160,RGS10,DNHD1,APBA2,SNPH,NUDT17,PCSK5 |
| 9.528e-09 | -18.47 | head development | biological process | GO:0060322 | 731 | 118 | 17256 | 1658 |
ID1,FGF13,RBFOX2,OTX1,PLXNA2,NDRG2,ABAT,BCAN,RAC3,CBLN1,AARS,CTNNA2,SKI,BAG3,RIDA,KCNAB1,EOMES,TACC2,DLX6,LHX6,DAB2IP,SYNGR3,ZNF365,SLIT2,POU3F3,GLI1,NKX2-1,FZD1,SMAD9,FZD4,WLS,SHANK2,LRRK2,ADCY1,NLGN4X,FEZ1,SATB2,EFHC1,AMIGO1,ATOH1,PLEKHA1,ASPH,FGFR1,EML1,TSKU,IRS2,ARMC4,NRG3,GNB4,LAMB1,PTPRS,OXTR,BMPR1A,DLX2,NRP1,PPARGC1A,CTTNBP2,CNTN1,TYRO3,BCL11B,MYO1D,GNG12,SCN5A,PCDH18,BMPR2,ROBO2,OPHN1,ZIC2,SELENOP,GDPD5,FOXG1,PHGDH,PGAP1,CHD5,DDIT4,KDM7A,FOXP2,NUMBL,HMGCS1,CNTN4,SLC7A11,GATA2,FLRT3,AFF2,PRKG1,LRP6,BNIP3,DYNC2H1,ATP2B1,PAK1,UNC5C,RAX,MSX1,RAPGEF2,ARID5B,SLITRK5,MAFB,AK4,PLCB1,CLN5,BAIAP2,ZIC1,DKK1,RERE,DOCK7,FAT4,MFSD2A,AKT3,GNAO1,GRIN2D,PAX9,BMP4,JHY,SEMA3A,CDH2,CRISPLD1,ATP2B4,SNPH |
| 9.578e-09 | -18.46 | KRIEG_HYPOXIA_NOT_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_NOT_VIA_KDM3A | 684 | 114 | 17377 | 1707 |
DOC2A,ZSWIM5,AVPI1,SYT12,RNF24,PRR7,KBTBD11,SEMA6A,FBXO32,KCTD15,POU5F1B,ALDOC,RAP2A,STARD4,TRPC1,DAB2IP,ENO1,TMEM120B,IL1RAP,PERP,GAB2,IGFBP3,TBC1D8,FZD1,SLC3A2,KCNIP3,GAPDH,ERGIC1,PDK1,PNRC1,TES,SLC39A8,TGFA,SHANK2,CAPN5,FGF12,NFIA,BNIP3L,VIM,ATP1B1,SAV1,NT5DC2,ISG20,IRS2,SLC39A14,GSN,GPRC5B,INSIG1,EIF4EBP1,P4HA2,ALDOA,PAM,P4HA1,ERCC5,TPM1,TANC2,MLLT3,PRKAA2,MXI1,ENO2,LGALS3,RIMKLA,SCD,FAM117B,SORBS3,CHSY1,SPIRE1,NEDD4,MTUS1,DDIT4,RAB11FIP5,CHN1,KIAA1958,KIAA1671,MSMO1,BACE2,MYC,STC2,PRELID2,FAM107B,SMTN,BNIP3,RRAS2,GPR161,DUSP1,ZNF629,PNMA2,QSOX1,DISC1,RIN2,RAB3B,KDM5B,PLEKHA8,FOXN3,MPP1,CYTH3,EFNA3,RASA3,AK4,CCNG1,FAM162A,TRIB3,CACHD1,MYADM,PLAGL1,PMEPA1,ADAMTS3,PLOD2,SLC7A5,HK2,KIAA0513,FBRSL1,HK1,CSRP2 |
| 9.612e-09 | -18.46 | GSE4590_SMALL_VS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_SMALL_VS_LARGE_PRE_BCELL_DN | 144 | 38 | 17377 | 1707 |
EXPH5,ARHGAP26,KLF8,DYRK3,AVPI1,LGALS3,PRSS16,SEC24D,RNF144A,ATP9A,SELL,RBM11,SEMA6A,PRRG4,EPCAM,SEC16B,PMAIP1,BHLHA15,MARVELD2,FAM107B,PACSIN1,ZFP36L2,CKAP4,CAND2,SMPDL3A,TRDMT1,ITGB7,EIF4E3,SPATA6,TES,KCNH5,CAPN5,VIM,DOCK5,KLF12,AKT3,SLC2A6,CMPK2 |
| 9.635e-09 | -18.46 | Neuronal System | REACTOME pathways | R-HSA-112316 | 349 | 67 | 10287 | 971 |
CACNG3,AKAP5,GRIK2,SYT12,BEGAIN,ABAT,NRXN1,PRKCA,CACNB4,EPB41L3,RPS6KA2,UNC13B,KCNN2,KCNAB1,CHRNA5,PPFIA2,KCNS3,LIN7A,PRKACB,KCNB2,KCNH5,SHANK2,ADCY1,CHRNA6,NLGN4X,KCND3,GJC1,GNAI1,KCNMB4,PRKCB,RASGRF2,GNB4,KCNG1,MAOA,PTPRS,APBA2,KCNV1,GNG12,PTPRD,GABRB2,GABRG2,SLC1A3,GABRR2,APBA1,KCNC4,KCNJ4,BCHE,CACNB2,KCNMB3,ADCY6,GRIP1,MYO6,STXBP1,DLGAP1,EPB41L5,ALDH2,KCNQ3,CACNA1E,HOMER2,PPFIA4,SNAP25,PLCB1,HOMER3,GRIK4,DLG2,GRIN2D,CACNA2D1 |
| 9.650e-09 | -18.46 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | 156 | 40 | 17377 | 1707 |
CARS,CHCHD7,CYP2J2,PLAG1,ITGA6,APBB1,YPEL2,SELL,RHPN2,FAM117B,PRKCA,HPCAL4,TXNRD3,NELL2,SPEG,TECPR1,SLC22A17,IGF1R,SREBF1,IPCEF1,STXBP1,SUSD3,CD55,PDK1,SFXN4,CAPN5,EFHC2,DCHS1,OBSCN,STRADB,TCEAL3,AMIGO1,TAF4B,CLN5,ZNF93,RNF157,NR3C2,SLC16A10,PKIA,PCSK5 |
| 1.047e-08 | -18.37 | GO_NEURON_PART | MSigDB lists | GO_NEURON_PART | 1222 | 180 | 17377 | 1707 |
DOC2A,PDE1B,FGF13,PRSS12,GRIK2,KIF5A,SYT12,ASS1,NDRG2,CADM2,ABAT,BCAN,DNER,RAC3,NCS1,PLS3,TUBB4A,BAG3,KCNN2,KCNAB1,PPFIA2,LIN7A,CTTN,PACSIN1,MYRIP,CPE,DBN1,ATL1,GPM6A,KCNIP3,ATF4,DCC,CAP2,WLS,ANK2,DNAJC6,LRRK2,FEZ1,EFHC1,PRKAR2B,KCND3,TRIM9,NCAM2,MAP2,PLK2,TMOD2,PPARGC1A,NRP1,APBA2,MAGI2,LZTS1,BCL11B,SV2B,SCN8A,OPHN1,SLC1A3,APBA1,PFN2,CA2,CNTN4,PDZD7,PDE10A,FLRT3,LRP6,GRIP1,MPDZ,BNIP3,CADPS2,STXBP1,RIMS2,CHRM3,ZNF385A,PAK1,DPYSL5,UNC5C,DISC1,KCNQ3,MYO10,HOMER2,SMARCD3,SDC3,RABAC1,SNAP25,CPEB1,HERPUD1,BAIAP2,DAGLA,GRIK4,RPL28,PTPRN2,SEMA3A,MME,DMXL2,DNM3,SCAMP1,AKAP5,ADD2,KCTD12,CANX,NRXN1,SEMA6A,PPP1R9A,PCLO,TIAM2,CTNNA2,CCDC120,NELL2,EPB41L3,UNC13B,GPRIN1,CHRNA5,DAB2IP,MARCKS,SCN2A,SYNGR3,KCNB2,SCN3A,FZD1,GARS,SHANK2,PREX1,NLGN4X,GSTO1,VIM,AMIGO1,TTLL7,GABARAPL1,SNCA,CAMK2N1,WFS1,ITGA2,PAM,BMPR1A,SEPT5,CTTNBP2,STON2,COBL,PSPH,CTNND2,MYO1D,SLC6A9,FARP1,BMPR2,ENO2,ROBO2,BACE1,LRP4,APBB1,EPS8,CLSTN2,GABRG2,KIF5C,P2RY1,EPHB1,GDPD5,KCNC4,ARHGAP44,RGS17,KCNJ4,SCN1B,SGK1,ATP2B1,DLGAP1,TRPM4,SLC40A1,RAB3B,MPP1,PTPN13,RAPGEF2,ARHGAP32,PALLD,MAP1B,DOCK7,ICA1,GNAO1,DLG2,KIF1B,ATP2B4,SNPH,ATP1A3 |
| 1.100e-08 | -18.33 | LEE_NEURAL_CREST_STEM_CELL_DN | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_DN | 110 | 32 | 17377 | 1707 |
COL9A3,GALNT12,PSTPIP2,BEGAIN,COL4A5,CREB5,GAS6,DOCK3,FOXG1,F3,MTUS1,EFEMP1,NELL2,CA2,FUT9,PMAIP1,CHRDL1,MPPED2,PRR16,SPRY2,GATM,SLIT2,IGFBP3,AGPAT4,ZBBX,FGF17,PALLD,DSP,PLEKHB1,ZIC1,PLAGL1,PLK2 |
| 1.124e-08 | -18.30 | central_nervous_system | COSMIC cancer mutations | central_nervous_system | 16807 | 1677 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,CHSY3,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 1.124e-08 | -18.30 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_UP | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_UP | 169 | 42 | 17377 | 1707 |
EFNB2,PLSCR4,CFH,ATP9A,LPCAT2,LRP4,ELOVL7,ARHGAP22,CD7,IKZF2,PPP1R9A,GAS1,MECOM,ATXN7L1,FKBP9,RNF150,SYCP2,ABLIM1,EEF2,BACE2,CDC14B,PPFIBP1,EHD3,ZNF521,PRKG2,LRP6,LIMCH1,PROS1,RAB27B,CHRM3,RIN2,NFIA,SAV1,SKAP1,PLOD2,PLXDC2,ATP7B,WWTR1,SPRY4,STON2,MLLT3,DIRC2 |
| 1.187e-08 | -18.25 | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP | MSigDB lists | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP | 188 | 45 | 17377 | 1707 |
TNIK,ATP8A1,ITGA6,BLVRB,PKP2,COL18A1,PSD3,TJP1,SPIRE1,EPDR1,MECOM,TGFBR3,CA2,ABCA5,GPR155,MARVELD2,ITGB3,STARD4,GHR,NBEA,GSTM3,ADCY6,CADPS2,NAP1L3,MAST4,MED12L,SNX7,MOB1B,EPB41L5,TBC1D8B,CYTH3,NFIA,RNF125,PRKAR2B,BEX4,GYPC,RNF217,PLXDC2,MAP9,ALG11,GRB10,HK1,MLLT3,HACE1,DENND5B |
| 1.198e-08 | -18.24 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma | 1299 | 188 | 17385 | 1698 |
EXPH5,GRIK2,PTPN21,FHDC1,NPM1,ENAH,NRN1,CTBP2,CEBPA,ANKRD18A,ADAMTS6,BCAN,KIAA1217,SLCO3A1,FSTL5,STK24,PCDH7,TRPS1,TXNDC5,ADPRHL1,SIPA1L2,RPS6KA2,DNAH6,COL19A1,ATRNL1,CNNM2,COG3,TLN2,ETV1,IL1RAP,SLIT2,TBC1D8,ITGB7,GPM6A,SESN2,ACVR1C,KLHL23,TGFA,ANK2,LRRK2,EFHC1,KCND3,ROR1,PLEKHA1,RNF44,GPC6,TSKU,GNAI1,SPNS1,GPRC5B,NCAM2,CCBE1,RASGRF2,TANC2,TMEFF2,APBA2,HS6ST3,EFNB2,SV2B,LRFN5,SCN5A,MRC2,CELSR1,TBC1D1,SCN8A,SETBP1,DYNC1I1,MLC1,SPINK5,MECOM,ABLIM1,RALGPS2,IGF1R,PDZD7,FRAS1,MYC,SREBF1,MPDZ,TOX,SLCO4C1,FIGN,COL9A2,RIMS2,EPB41L5,PCDH10,SLITRK2,BTNL9,MYO10,COL4A4,DCHS1,EFHC2,FASN,KIAA1324L,RYR2,WWC1,OBSCN,PRDM1,SDK1,ZNF558,MMP15,RPL28,PMEPA1,FAT1,CECR2,MFSD2A,PLD1,EPHA3,MSR1,MORC4,LPIN3,TNKS1BP1,TBC1D30,PPP1R9A,DDX60L,PCLO,EPB41L3,TMEM53,CDC14B,TACC2,ALDH1L1,EEPD1,BCL6,SHF,RTKN2,MYH15,FHIT,WWC2,SERPINH1,DNAH5,SCN3A,GLI1,TMEM67,PTPRU,PRDM13,CHRNA6,PRKCQ,CD40,DSP,TTC28,ZNF569,ARHGAP21,ZNF93,NRG3,LAMB1,PTPRS,FAM149A,GRB10,PLD5,LRRC27,HOXB9,CTTNBP2,ZNF701,C8orf48,CTNND2,PSPH,HACE1,TNIK,PRSS16,ARHGEF11,ATP9A,GDPD5,HOPX,LRRC55,SCN1B,FUT9,GPR155,AFF2,EIF1,KIAA0319,TRIM3,RALGAPA2,PNMA2,CARD6,SH3BP2,HNF4G,CRIM1,LRRIQ1,CACNA1E,AGAP2,NAALADL2,LEPR,ICA1,FAT4,FBN1,THSD7B,MYOM2,ZNF474,TBC1D4 |
| 1.198e-08 | -18.24 | plasma_cell_myeloma | COSMIC cancer mutations | plasma_cell_myeloma | 1299 | 188 | 17385 | 1698 |
EXPH5,GRIK2,PTPN21,FHDC1,NPM1,ENAH,NRN1,CTBP2,CEBPA,ANKRD18A,ADAMTS6,BCAN,KIAA1217,SLCO3A1,FSTL5,STK24,PCDH7,TRPS1,TXNDC5,ADPRHL1,SIPA1L2,RPS6KA2,DNAH6,COL19A1,ATRNL1,CNNM2,COG3,TLN2,ETV1,IL1RAP,SLIT2,TBC1D8,ITGB7,GPM6A,SESN2,ACVR1C,KLHL23,TGFA,ANK2,LRRK2,EFHC1,KCND3,ROR1,PLEKHA1,RNF44,GPC6,TSKU,GNAI1,SPNS1,GPRC5B,NCAM2,CCBE1,RASGRF2,TANC2,TMEFF2,APBA2,HS6ST3,EFNB2,SV2B,LRFN5,SCN5A,MRC2,CELSR1,TBC1D1,SCN8A,SETBP1,DYNC1I1,MLC1,SPINK5,MECOM,ABLIM1,RALGPS2,IGF1R,PDZD7,FRAS1,MYC,SREBF1,MPDZ,TOX,SLCO4C1,FIGN,COL9A2,RIMS2,EPB41L5,PCDH10,SLITRK2,BTNL9,MYO10,COL4A4,DCHS1,EFHC2,FASN,KIAA1324L,RYR2,WWC1,OBSCN,PRDM1,SDK1,ZNF558,MMP15,RPL28,PMEPA1,FAT1,CECR2,MFSD2A,PLD1,EPHA3,MSR1,MORC4,LPIN3,TNKS1BP1,TBC1D30,PPP1R9A,DDX60L,PCLO,EPB41L3,TMEM53,CDC14B,TACC2,ALDH1L1,EEPD1,BCL6,SHF,RTKN2,MYH15,FHIT,WWC2,SERPINH1,DNAH5,SCN3A,GLI1,TMEM67,PTPRU,PRDM13,CHRNA6,PRKCQ,CD40,DSP,TTC28,ZNF569,ARHGAP21,ZNF93,NRG3,LAMB1,PTPRS,FAM149A,GRB10,PLD5,LRRC27,HOXB9,CTTNBP2,ZNF701,C8orf48,CTNND2,PSPH,HACE1,TNIK,PRSS16,ARHGEF11,ATP9A,GDPD5,HOPX,LRRC55,SCN1B,FUT9,GPR155,AFF2,EIF1,KIAA0319,TRIM3,RALGAPA2,PNMA2,CARD6,SH3BP2,HNF4G,CRIM1,LRRIQ1,CACNA1E,AGAP2,NAALADL2,LEPR,ICA1,FAT4,FBN1,THSD7B,MYOM2,ZNF474,TBC1D4 |
| 1.265e-08 | -18.19 | somatodendritic compartment | cellular component | GO:0036477 | 778 | 122 | 18223 | 1724 |
DNM3,CACNG3,PDE1B,FGF13,GRIK2,PRSS12,C4A,KIF5A,LDLR,ABHD13,ASS1,CANX,KIF21B,NRXN1,PRR7,DNER,RAC3,PPP1R9A,NCS1,TUBB4A,KCNAB1,KCNN2,DAB2IP,CTTN,CPE,KCNB2,DBN1,GPM6A,KCNIP3,ATF4,FZD4,WLS,SHANK2,LRRK2,PREX1,NLGN4X,FEZ1,PRKAR2B,EFHC1,KCND3,AMIGO1,CD40,TTLL7,GABARAPL1,SNCA,CAMK2N1,TRIM9,HTR7,MAP2,PLK2,WFS1,RGS10,PAM,PTPRS,SERPINI1,INPP5F,BMPR1A,NRP1,PPARGC1A,APBA2,MAGI2,CTTNBP2,LZTS1,COBL,CTNND2,PRKAA2,MYO1D,FARP1,NECAB2,BMPR2,ENO2,APBB1,LRP4,OPHN1,SLC25A27,GABRG2,KIF5C,P2RY1,SLC1A3,EPHB1,APBA1,KCNC4,GDPD5,NEDD4,ARHGAP44,MAP1A,PDE10A,LRP6,GRIP1,TRIM3,MPDZ,BNIP3,NPTXR,ZNF385A,ATP2B1,CHRM3,PAK1,TRPM4,DPYSL5,BDNF,MYO10,RAPGEF2,HOMER2,ARHGAP32,SNAP25,RACK1,OR11H4,CPEB1,BAIAP2,HOMER3,MAP1B,RPL28,SH3GL2,GNAO1,CTSV,MPP2,SEMA3A,KIF1B,SHTN1,MME,ATP1A3,SNPH |
| 1.275e-08 | -18.18 | MODULE_12 | MSigDB lists | MODULE_12 | 350 | 69 | 17377 | 1707 |
UGT8,TRIM2,TRIM16,LDLR,ABAT,NOVA1,F3,RTN1,EPB41L3,BCL6,SERPINH1,CPE,HSPA2,GATM,SLIT2,IGFBP3,CYP1B1,DBN1,GPM6A,COL6A2,FEZ1,TMEM47,RARRES2,DSP,FGFR1,GNAI1,GPRC5B,WWTR1,ZBTB20,SERPINI1,PIK3C2B,TPM1,APBA2,TYRO3,GNG12,RGS16,COL9A3,WASF3,IGFBP6,FN1,ENO2,ITGA6,ATP9A,APBB1,KIF5C,SLC1A3,SATB1,MLC1,GAS1,HOPX,DDIT4,MTUS1,ABLIM1,MSMO1,PCBP4,SMTN,NCAM1,FADS1,CRIM1,NR4A1,PTPN13,FERMT2,PDE8A,SNAP25,ZIC1,FAT1,RAB31,KIAA0513,CDH2 |
| 1.352e-08 | -18.12 | acute_myeloid_leukaemia | COSMIC cancer mutations | acute_myeloid_leukaemia | 10696 | 1150 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,TXNDC5,PPP2R2B,CPE,DCC,KLHL23,EXOC6B,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,ENPP1,ATP7B,MAP9,BDH2,ERCC5,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,ALPK1,DENND1C,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,TLR3,ALDH1L1,FAM133A,DNAH5,ZNF365,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,CCDC148,WDR17,GCAT,FZD8,ESRP1,UBAC2,PSD3,CBS,SLC12A6,EPHB1,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,RAB6B,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,PHACTR3,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,ITGB3,JAKMIP2,ENO1,PGBD5,DBN1,MARK1,ATF4,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,INSIG1,KLF12,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,STXBP5L,SORBS3,ZNF215,FHOD3,NUMBL,ZNF440,FRAS1,SMTN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,OBSCN,SDK1,KHDRBS2,NEGR1,TBC1D2,GRIK4,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,RPS13,INTU,TDRD3,ACO1,RNF125,CHRNA6,PTPRJ,RNF217,PTPRS,MAOA,HGF,CTNND2,TENM1,SLC6A9,NECAB2,BMPR2,MCTP2,USP30,SLC35F1,FOXP2,TTC1,GTF2F2,TSC22D1,SGK1,KIAA0408,SYK,DUSP1,LRRIQ1,FERMT2,PRICKLE1,PALLD,MGMT,SMPDL3B,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,ZFYVE28,SERINC2,NDUFB8,KCNS3,GLDC,GDAP1,WISP3,LRMP,BNIP3L,EFHC1,GNAI1,SH3RF1,ENPP6,BMP1,SERPINI1,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,ST6GAL1,DHCR24,LRRC49,APBA1,TNFRSF19,MTUS1,ABLIM1,RALGPS2,SLC7A11,MYC,PRKG1,SREBF1,CPXM2,GRIP1,FAM155A,COL9A2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,PLEKHH2,CECR2,THBS4,C1orf21,LRRIQ3,MATN2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,SPEG,ASNS,ZNF438,POU5F1B,PDE4D,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,SATB2,CBY1,ATP10D,IKZF3,TDO2,CCNA1,ZNF704,HPGD,COBL,STON2,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,INPP1,RASSF8,LRRC55,AFF2,GPR155,DYNC2H1,TBC1D9,B4GALT6,TMC7,VAV3,SLC40A1,ARHGEF28,SH3BP2,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,HMCN1,CHST10,ADPRHL1,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,CNNM2,TRPC1,MYRIP,IL1RAP,PDGFRB,SESN2,SKAP2,JPH1,TMEM47,SGK2,GPRC5B,FAM114A2,CCDC169,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,RHOBTB1,BVES,STXBP6,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,GSTM4,STEAP1,HERPUD1,TMEM154,PLAGL1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,XKR4,DMXL2,PSTPIP2,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,PDZD8,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,FHIT,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,BATF3,BCL11A,ZNF569,ARMC4,ZNF93,TRIM34,RBPMS2,TMPRSS9,RGS10,RNF130,ENO2,ARHGEF11,TSPAN15,CMTM8,SSX1,COL4A5,IGF2BP2,FAM174B,SEL1L3,BMP6,SYDE2,RAB11FIP5,FSD1,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,PRSS12,AASS,CADM2,STAT5B,DOCK3,NHP2,CA8,NOS1AP,EYA4,PCDH7,BAG3,TGFBR3,FBXO32,PMAIP1,DNAH6,FAAH2,PPFIA2,TSHR,KLHL29,MEIS2,GJB2,CAP2,TGFA,WLS,ELMOD1,F12,MFSD6,CA13,ALDOA,ARHGAP28,TMEFF2,MEF2C,CRYL1,CARS,GNG12,STOX2,CYP2J2,SYCP2,KIAA1671,FAM189A1,CACNB2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,RPS23,SLC37A1,MYO10,STAT4,CALCRL,RYR2,PLS1,C1R,TAF4B,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,GALNT12,GALNT6,C4A,FAM131C,MYO1B,LRRCC1,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,JAKMIP3,FAM155B,SCN3A,DOCK8,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,TTC28,FGFR1,METAP1D,IQCK,IQCH,GYPC,INPP4B,PLEKHG1,ALG11,TNFSF15,DBP,PLD5,KLHL31,TMEM132C,FARP1,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,COL27A1,NEO1,NPTXR,MYO6,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,HEG1,PTPRC,GALNT3,ID3,TRIB3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,DCBLD1,NBPF4,TRIM2,FAM227A,FHDC1,LILRB1,ASS1,SYT14,NOVA1,FSTL5,KCNN2,KCNAB1,HPS1,MARVELD2,LIN7A,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,GCNT2,ABCC4,GDPD1,TCERG1L,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,CCDC146,TECPR2,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,ZCCHC24,UBASH3B,SETBP1,MLC1,PGAP1,IL18R1,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,GATA2,BCHE,PDE10A,SAMD11,FBXL2,CHSY3,UNC5C,RNF170,SLC27A2,SPATA13,TCEA3,TMTC4,PPFIA4,WDR25,PDE8A,TEX9,MAPKAPK2,ATPAF2,CSF1,MFSD2A,PANK3,MME,CFH,AKAP5,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,LPIN3,SEZ6L2,PCLO,CYP26A1,TBC1D19,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,GBP1,PTK7,ABI3,ITGA2,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,COL9A3,IL32,RUSC2,APBB1,SELL,GABRG2,ARHGAP44,TECPR1,MAP1A,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,DLGAP1,MICAL2,PPP1R3D,NUAK2,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,ZNF808,RPL4,TBC1D4,FILIP1,CGN,MYCBP2,ACVR1,SIDT1,ATP8A1,PPFIBP2,ENAH,DACH2,NCS1,STK24,SLC22A18,CFHR1,FAM168A,CHRDL1,ATRNL1,GSTM3,VWA5A,TBC1D8,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,TNS1,ACVR2B,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,RASGRF2,ENTPD7,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ZHX3,PTPRD,SCN8A,OLAH,OPHN1,SLC25A27,GTF2IRD1,WDFY4,SLC1A3,ISYNA1,DYNC1I1,ADSSL1,NIPSNAP3B,RPL13A,PRRG4,MCOLN2,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,OPN3,PRELID1,SLC16A9,TSPAN12,MPDZ,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,COL4A4,CCDC85A,C4orf19,PLCB1,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,ACSM3,PLA2G4A,EPHA3,FRMPD3,TBKBP1,AMOTL1,RASAL2,ELOVL4,RNF144A,GPR65,ZNF311,CHUK,SPATS2L,ZNF827,TMEM53,NBEA,SCRN1,VNN2,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,MAP3K21,GRB10,CTTNBP2,NR3C2,THOC3,DENND5B,WASF3,ANO10,MXI1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,MGAT1,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,ARAP2,SYNPO2,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,GPLD1,OR2T33,NUTM2A,TUFT1,MYOM2,NUDT17,ATP1A3,SLC43A1,EXPH5,MPZL3,KIF5A,UGDH,ANKRD18A,ABAT,CACNB4,RBM11,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,CYP51A1,ARHGEF10L,RTN1,LRRC6,GRHL1,AKAP7,SLC10A7,POF1B,PTPRE,OR2W3,FANK1,SLIT2,RASGRP1,ATL1,CAPN5,ZNF565,ROR1,EML1,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,CYP4V2,LAMC3,GALNT13,SATB1,CD7,CA2,RPS11,FAM107B,NCEH1,MORN4,NOS3,ANKRD20A2,IL17RD,RAX,MSTN,PARD3B,EDEM3,WWC1,LHPP,PRDM1,B4GALNT3,RAI14,HK2,DIRC2,CREB3L2,EML5,ZSWIM5,NEK10,CELSR3,IL15,PLEKHA5,TDRKH,DOCK2,UBTD2,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,MET,WWC2,ZNF460,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,DOCK5,TTLL7,C1orf174,TPK1,LMLN,BACH2,DISP1,LIFR,OR51B5,TNIK,CLGN,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,ESRRG,CYTH3,GRID1,OGDHL,MEI1,PHACTR2,ARHGAP32,ZFPM2,C3orf70,RERE,MAP1B,GPR37,ADAMTS17,NACC2,MPP7,MAP2K6,PRCP,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SLC16A10 |
| 1.352e-08 | -18.12 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia | 10696 | 1150 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,TXNDC5,PPP2R2B,CPE,DCC,KLHL23,EXOC6B,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,INTS6,ENPP1,ATP7B,MAP9,BDH2,ERCC5,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,ALPK1,DENND1C,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,CLN5,SPATA7,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,TLR3,ALDH1L1,FAM133A,DNAH5,ZNF365,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,CCDC148,WDR17,GCAT,FZD8,ESRP1,UBAC2,PSD3,CBS,SLC12A6,EPHB1,HMGCS1,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,RAB6B,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,PHACTR3,TRIM16,LMCD1,MGAT5B,ITPR2,FAM13A,CCNJ,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,ITGB3,JAKMIP2,ENO1,PGBD5,DBN1,MARK1,ATF4,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,INSIG1,KLF12,AHNAK2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,STXBP5L,SORBS3,ZNF215,FHOD3,NUMBL,ZNF440,FRAS1,SMTN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,CKAP4,DPYSL5,BTNL9,MGAT4B,GPSM1,STRADB,OBSCN,SDK1,KHDRBS2,NEGR1,TBC1D2,GRIK4,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,RPS13,INTU,TDRD3,ACO1,RNF125,CHRNA6,PTPRJ,RNF217,PTPRS,MAOA,HGF,CTNND2,TENM1,SLC6A9,NECAB2,BMPR2,MCTP2,USP30,SLC35F1,FOXP2,TTC1,GTF2F2,TSC22D1,SGK1,KIAA0408,SYK,DUSP1,LRRIQ1,FERMT2,PRICKLE1,PALLD,MGMT,SMPDL3B,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,ZFYVE28,SERINC2,NDUFB8,KCNS3,GLDC,GDAP1,WISP3,LRMP,BNIP3L,EFHC1,GNAI1,SH3RF1,ENPP6,BMP1,SERPINI1,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,ST6GAL1,DHCR24,LRRC49,APBA1,TNFRSF19,MTUS1,ABLIM1,RALGPS2,SLC7A11,MYC,PRKG1,SREBF1,CPXM2,GRIP1,FAM155A,COL9A2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,PLEKHH2,CECR2,THBS4,C1orf21,LRRIQ3,MATN2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,SPEG,ASNS,ZNF438,POU5F1B,PDE4D,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,SATB2,CBY1,ATP10D,IKZF3,TDO2,CCNA1,ZNF704,HPGD,COBL,STON2,HACE1,MYO1D,PLSCR4,EPS8,PRSS35,HERC5,INPP1,RASSF8,LRRC55,AFF2,GPR155,DYNC2H1,TBC1D9,B4GALT6,TMC7,VAV3,SLC40A1,ARHGEF28,SH3BP2,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,HMCN1,CHST10,ADPRHL1,LGI2,PPM1E,SIPA1L2,ABI3BP,ANKFN1,CNNM2,TRPC1,MYRIP,IL1RAP,PDGFRB,SESN2,SKAP2,JPH1,TMEM47,SGK2,GPRC5B,FAM114A2,CCDC169,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,RHOBTB1,BVES,STXBP6,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,LIMCH1,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,GSTM4,STEAP1,HERPUD1,TMEM154,PLAGL1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,XKR4,DMXL2,PSTPIP2,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,PDZD8,PPFIBP1,KAZN,C12orf60,REEP1,ACVR2A,FHIT,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,BATF3,BCL11A,ZNF569,ARMC4,ZNF93,TRIM34,RBPMS2,TMPRSS9,RGS10,RNF130,ENO2,ARHGEF11,TSPAN15,CMTM8,SSX1,COL4A5,IGF2BP2,FAM174B,SEL1L3,BMP6,SYDE2,RAB11FIP5,FSD1,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LEPR,CTIF,DPY19L2,ICA1,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,GXYLT2,PDE1B,FLVCR2,PRSS12,AASS,CADM2,STAT5B,DOCK3,NHP2,CA8,NOS1AP,EYA4,PCDH7,BAG3,TGFBR3,FBXO32,PMAIP1,DNAH6,FAAH2,PPFIA2,TSHR,KLHL29,MEIS2,GJB2,CAP2,TGFA,WLS,ELMOD1,F12,MFSD6,CA13,ALDOA,ARHGAP28,TMEFF2,MEF2C,CRYL1,CARS,GNG12,STOX2,CYP2J2,SYCP2,KIAA1671,FAM189A1,CACNB2,LOXL4,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,RPS23,SLC37A1,MYO10,STAT4,CALCRL,RYR2,PLS1,C1R,TAF4B,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,GALNT12,GALNT6,C4A,FAM131C,MYO1B,LRRCC1,PKP2,IL13RA1,NRXN1,LCP2,COLEC10,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,JAKMIP3,FAM155B,SCN3A,DOCK8,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,TTC28,FGFR1,METAP1D,IQCK,IQCH,GYPC,INPP4B,PLEKHG1,ALG11,TNFSF15,DBP,PLD5,KLHL31,TMEM132C,FARP1,ROBO2,IPO5,NKAIN2,CREB5,PKN1,KCNC4,COL27A1,NEO1,NPTXR,MYO6,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,HEG1,PTPRC,GALNT3,ID3,TRIB3,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,DCBLD1,NBPF4,TRIM2,FAM227A,FHDC1,LILRB1,ASS1,SYT14,NOVA1,FSTL5,KCNN2,KCNAB1,HPS1,MARVELD2,LIN7A,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,GCNT2,ABCC4,GDPD1,TCERG1L,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,CCDC146,TECPR2,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,ZCCHC24,UBASH3B,SETBP1,MLC1,PGAP1,IL18R1,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,GATA2,BCHE,PDE10A,SAMD11,FBXL2,CHSY3,UNC5C,RNF170,SLC27A2,SPATA13,TCEA3,TMTC4,PPFIA4,WDR25,PDE8A,TEX9,MAPKAPK2,ATPAF2,CSF1,MFSD2A,PANK3,MME,CFH,AKAP5,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,LPIN3,SEZ6L2,PCLO,CYP26A1,TBC1D19,MYO3B,SCN2A,CLVS2,FAM78B,GLI1,CTH,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,GBP1,PTK7,ABI3,ITGA2,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,COL9A3,IL32,RUSC2,APBB1,SELL,GABRG2,ARHGAP44,TECPR1,MAP1A,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,DLGAP1,MICAL2,PPP1R3D,NUAK2,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,ZNF808,RPL4,TBC1D4,FILIP1,CGN,MYCBP2,ACVR1,SIDT1,ATP8A1,PPFIBP2,ENAH,DACH2,NCS1,STK24,SLC22A18,CFHR1,FAM168A,CHRDL1,ATRNL1,GSTM3,VWA5A,TBC1D8,EML6,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,TNS1,ACVR2B,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,RASGRF2,ENTPD7,CCBE1,B3GALT2,SEMA3C,UNC5B,TANC2,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ZHX3,PTPRD,SCN8A,OLAH,OPHN1,SLC25A27,GTF2IRD1,WDFY4,SLC1A3,ISYNA1,DYNC1I1,ADSSL1,NIPSNAP3B,RPL13A,PRRG4,MCOLN2,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,OPN3,PRELID1,SLC16A9,TSPAN12,MPDZ,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,COL4A4,CCDC85A,C4orf19,PLCB1,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,ACSM3,PLA2G4A,EPHA3,FRMPD3,TBKBP1,AMOTL1,RASAL2,ELOVL4,RNF144A,GPR65,ZNF311,CHUK,SPATS2L,ZNF827,TMEM53,NBEA,SCRN1,VNN2,TMEM43,SFXN4,PRKCQ,TBC1D16,DCBLD2,HTR7,PRKCB,MAP3K21,GRB10,CTTNBP2,NR3C2,THOC3,DENND5B,WASF3,ANO10,MXI1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,MGAT1,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,ARAP2,SYNPO2,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,GPLD1,OR2T33,NUTM2A,TUFT1,MYOM2,NUDT17,ATP1A3,SLC43A1,EXPH5,MPZL3,KIF5A,UGDH,ANKRD18A,ABAT,CACNB4,RBM11,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,CYP51A1,ARHGEF10L,RTN1,LRRC6,GRHL1,AKAP7,SLC10A7,POF1B,PTPRE,OR2W3,FANK1,SLIT2,RASGRP1,ATL1,CAPN5,ZNF565,ROR1,EML1,TMEM132B,AK1,NCAM2,ITGBL1,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,ELOVL7,CYP4V2,LAMC3,GALNT13,SATB1,CD7,CA2,RPS11,FAM107B,NCEH1,MORN4,NOS3,ANKRD20A2,IL17RD,RAX,MSTN,PARD3B,EDEM3,WWC1,LHPP,PRDM1,B4GALNT3,RAI14,HK2,DIRC2,CREB3L2,EML5,ZSWIM5,NEK10,CELSR3,IL15,PLEKHA5,TDRKH,DOCK2,UBTD2,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,MET,WWC2,ZNF460,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,DOCK5,TTLL7,C1orf174,TPK1,LMLN,BACH2,DISP1,LIFR,OR51B5,TNIK,CLGN,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,NKX6-1,CHN2,GTSF1,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,ESRRG,CYTH3,GRID1,OGDHL,MEI1,PHACTR2,ARHGAP32,ZFPM2,C3orf70,RERE,MAP1B,GPR37,ADAMTS17,NACC2,MPP7,MAP2K6,PRCP,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,SLC16A10 |
| 1.438e-08 | -18.06 | BASAKI_YBX1_TARGETS_DN | MSigDB lists | BASAKI_YBX1_TARGETS_DN | 351 | 69 | 17377 | 1707 |
DMXL2,SCAMP1,CNTNAP3,DNAJC3,ASS1,COBLL1,HECW2,SEZ6L2,FAM13A,PPP1R9A,SCIN,SLC22A18,ALDOC,GSTM3,PROS1,TMEM37,MET,CD55,MEIS2,PDK1,GDPD1,DEPTOR,TMEM47,PLEKHA1,SGK2,ASPH,ISG20,CAMK2N1,LAMB1,BDH2,P4HA1,DBP,MBOAT2,RRAGD,HEY1,C2orf88,MXI1,GRB14,SLC25A27,PSD3,SCD,DDIT4,NAV1,SLC7A11,ABCA5,FAM189A1,FLRT3,GAS2L3,FAM107B,DYNC2H1,MAST4,TNFRSF11A,SPRY2,SLC45A3,SMPDL3A,PCSK6,SLC40A1,VAV3,PNP,VLDLR,AK4,SNTB1,GALNT14,FAM162A,GALNT3,PLOD2,HK2,DYNC2LI1,ACSM3 |
| 1.472e-08 | -18.03 | axonogenesis | biological process | GO:0007409 | 366 | 70 | 17256 | 1658 |
CELSR3,KIF5A,PLXNA2,GATA3,ENAH,PRKCA,NRXN1,SEMA6A,CTNNA2,COL25A1,ETV1,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,ATL1,EVL,DCC,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,TSKU,IRS2,MAP2,GRB10,SEMA3C,NRP1,UNC5B,COBL,EFNB2,BCL11B,LRFN5,ROBO2,APBB1,OPHN1,KIF5C,EPHB1,FOXG1,DOK5,NEO1,CHN1,NUMBL,LRRC55,LRRN1,SEMA4F,MAP1A,CNTN4,SCN1B,FLRT3,NCAM1,STXBP1,GFRA1,DPYSL5,PDLIM7,UNC5C,BDNF,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,MAP1B,DOCK7,MATN2,SEMA3A,NKX2-8,SHTN1 |
| 1.476e-08 | -18.03 | GO_CELL_PART_MORPHOGENESIS | MSigDB lists | GO_CELL_PART_MORPHOGENESIS | 596 | 102 | 17377 | 1707 |
NBL1,UGT8,TCTN2,CELSR3,RBFOX2,KIF5A,PLXNA2,GATA3,ENAH,NRXN1,PIBF1,SEMA6A,CTNNA2,EPB41L3,LRRC6,COL25A1,DAB2IP,CTTN,PACSIN1,SNX10,ETV1,DNAH5,SLIT2,NTNG1,SEMA6C,NKX2-1,INTU,ATL1,GPM6A,TMEM67,EVL,ABCC4,DCC,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,TSKU,ARMC4,GSN,IFT81,MAP2,WWTR1,SEMA3C,UNC5B,NRP1,LIFR,COBL,CTNND2,EFNB2,BCL11B,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,EPHB1,BBS9,TTC30B,NEO1,CHN1,ABLIM1,NUMBL,LRRC55,CNTN4,SEMA4F,LRRN1,SCN1B,FLRT3,EHD3,SGK1,DYNC2H1,NCAM1,STXBP1,PAK1,DPYSL5,B9D1,BDNF,UNC5C,DISC1,SLITRK2,SPATA6,VLDLR,EFNA3,TTC30A,SLITRK5,BAIAP2,MAP1B,RERE,DOCK7,TMEM237,THBS4,MATN2,WDR19,DYNC2LI1,FNBP1L,NKX2-8,SEMA3A |
| 1.586e-08 | -17.96 | ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP | MSigDB lists | ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_UP | 255 | 55 | 17377 | 1707 |
TNIK,BTC,FZD8,ESRP1,ZNF311,MCOLN3,OPHN1,HECW2,KIF5C,SLC1A3,CREB5,SLC12A6,SYT14,KIAA1217,SATB1,TBC1D30,SPIRE1,MCU,SCIN,ZNF827,CACNB2,FRAS1,VWDE,COL19A1,SLC16A9,LIMCH1,TOX,IPCEF1,DYNC2H1,MAST4,DOCK8,CHRM3,FZD1,QSOX1,LCA5,MARK1,SMAD9,MPP1,C3orf52,ELMOD1,MSRB3,PRKCQ,PRKAR2B,SDK1,PALLD,HTR7,ENPP6,AKT3,PELI2,PAM,SEMA3C,TMOD2,TANC2,MBOAT2,MLLT3 |
| 1.593e-08 | -17.95 | axon development | biological process | GO:0061564 | 396 | 74 | 17256 | 1658 |
EPHA3,CELSR3,KIF5A,PLXNA2,GATA3,ENAH,PRKCA,NRXN1,DDR1,SEMA6A,CTNNA2,COL25A1,ETV1,NTNG1,SLIT2,SEMA6C,GAB2,NKX2-1,ATL1,EVL,DCC,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,JAM3,TSKU,IRS2,NCAM2,MAP2,GRB10,SEMA3C,NRP1,UNC5B,COBL,BCL11B,EFNB2,LRFN5,ROBO2,APBB1,OPHN1,KIF5C,EPHB1,FOXG1,DOK5,NEO1,CHN1,NUMBL,LRRC55,LRRN1,SEMA4F,MAP1A,CNTN4,SCN1B,FLRT3,NCAM1,STXBP1,GFRA1,DPYSL5,PDLIM7,UNC5C,BDNF,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,MAP1B,DOCK7,MATN2,NKX2-8,SEMA3A,SHTN1 |
| 1.618e-08 | -17.94 | DELYS_THYROID_CANCER_DN | MSigDB lists | DELYS_THYROID_CANCER_DN | 222 | 50 | 17377 | 1707 |
EPHA3,WASF3,COL9A3,RGS16,FGF13,GCAT,GRB14,SETBP1,NRN1,NUP62CL,PCLO,GAS1,RGS17,EPB41L3,TGFBR3,KCNAB1,SLC16A2,PDE10A,GHR,CHRDL1,MPPED2,GSTM3,IPCEF1,NCAM1,ZFP36L2,NEB,PRKACB,CTH,GLDC,HBG2,MEIS2,ALDH2,ESRRG,RYR2,FEZ1,PRKCQ,ZFPM2,ASPH,EML1,GNAI1,ID3,ENPP1,HLF,WFS1,MATN2,CLMN,DLG2,TBC1D4,LIFR,CSRP2 |
| 1.626e-08 | -17.93 | RIGGI_EWING_SARCOMA_PROGENITOR_DN | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_DN | 171 | 42 | 17377 | 1707 |
GXYLT2,AVPI1,RUNX2,ZNF395,IGFBP6,CLGN,GALNT12,BACE1,PSD3,GPSM2,LACC1,TNFRSF19,SNX9,COL14A1,FHOD3,RPS6KA2,TGFBR3,STC2,SRGAP1,ZNF521,SLC2A12,GULP1,PCOLCE2,FAR2,MOXD1,RAB27B,ETV1,COL6A2,PDK1,WLS,C1R,PLCB1,GPC6,HEG1,EBF1,CCBE1,HGF,BMP4,TANC2,NRP1,MMP16,MME |
| 1.725e-08 | -17.88 | ACCAAAG,MIR-9 | MSigDB lists | ACCAAAG,MIR-9 | 469 | 85 | 17377 | 1707 |
PLBD2,TRIM2,ELOVL4,RNF144A,RBFOX2,HECW2,KCTD12,ADAMTS6,RNF24,KIAA1217,SLC19A2,PCDH7,TXNDC5,RNF150,ZNF362,IKZF5,GRHL1,BCL6,MAP7,CNNM2,JAKMIP2,PACSIN1,FAM155B,ZNF365,NTNG1,PDGFRB,GAB2,TBC1D8,PHLDB2,KLHL3,ANK2,FGF12,ATP1B1,BCL11A,SLC39A14,DYRK1B,RANBP2,KLF12,INSIG1,P4HA2,KLF5,LPP,RUNX2,FARP1,ZNF395,RHOBTB1,BACE1,UBASH3B,YPEL2,FAM117B,SORBS3,IGF2BP2,CREB5,FOXG1,PGAP1,NEDD4,CNTN4,MAP1A,FRY,ZNF354A,FLRT3,RASD2,FAM107B,FBXL2,VGLL4,RIMS2,SNX7,PCSK6,VAV3,CRIM1,EDEM3,PRDM1,ATP11A,CCNG1,MAP1B,MAPKAPK2,GALNT3,FBN1,SH3BGRL2,KIF21A,FNBP1L,PANK3,MMP16,LARP1,DOCK9 |
| 1.769e-08 | -17.85 | GSE14415_INDUCED_TREG_VS_TCONV_DN | MSigDB lists | GSE14415_INDUCED_TREG_VS_TCONV_DN | 147 | 38 | 17377 | 1707 |
EML5,LATS2,MOCOS,TCP11L2,SIDT1,PRSS12,ELOVL7,ADAMTS6,ITPR2,KBTBD11,BBS9,SLCO3A1,PRRG4,OTUD1,FBXO32,GPR155,RAP2A,MYO3B,PJA1,SPRY2,RASGRP1,SMPDL3A,CARD6,CD55,KDM5B,RAB6B,TMEM65,CRIM1,SPATA6,NFE2L1,ST6GALNAC3,MFSD6,SMAD3,ZBTB20,RPL4,HS3ST3B1,NRP1,SMYD3 |
| 1.775e-08 | -17.85 | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | 629 | 106 | 17377 | 1707 |
BTC,AVPI1,PRSS12,PLEKHA5,ENAH,CTBP2,NTRK3,UBTD2,KREMEN1,NCS1,FSTL5,FKBP11,PCDH7,ZNF827,KAZN,RAP2A,RAB26,MPPED2,ZNF521,GSTM3,JAKMIP2,NAP1L3,BEND4,GULP1,POU2F2,THSD1,RAPGEF5,KIAA1549,ERGIC1,SMAD9,TES,DEPTOR,TTC22,WNT11,KCND3,RAB38,TCERG1L,SESN1,TBC1D16,CA13,EML1,TPK1,KLF12,RNF217,NCAM2,SH3RF1,PEMT,ZNF704,ALG11,DISP1,MAGI2,KCTD1,MEF2C,LATS2,TNIK,STOX2,RUNX2,RHOBTB1,GCAT,GABRB2,ITGA6,FZD8,UBASH3B,SCN8A,CYP4V2,IGF2BP2,ISYNA1,USP30,SYDE2,NAV1,ADCK1,GATA2,PAIP2B,PRICKLE2,SH3PXD2B,FAM84B,PTPRCAP,STXBP1,FAM155A,CAND2,KIAA1211,BOD1,ZNF629,RNF152,MN1,QSOX1,USP2,FASN,AGAP2,LHPP,RABAC1,ARHGAP32,C3orf70,TAF4B,PEAK1,ILDR2,LDHD,CPEB1,DAGLA,PLXDC2,C1orf21,WDR19,RAI14,FNBP1L,DCBLD1,PHC1 |
| 1.838e-08 | -17.81 | VERHAAK_AML_WITH_NPM1_MUTATED_DN | MSigDB lists | VERHAAK_AML_WITH_NPM1_MUTATED_DN | 236 | 52 | 17377 | 1707 |
SERINC5,NBL1,SIDT1,FGF13,ATP9A,ITGA6,XYLT1,EPS8,GATA3,ASS1,GPSM2,CD7,NEDD4,HOPX,MECOM,ABLIM1,RPS6KA2,PMAIP1,EHD3,RAP2A,SCRN1,TSPAN13,TOX,NCAM1,PTPRCAP,LRP3,GATM,B4GALT6,TRPM4,MN1,PRAME,ARAP2,ALDH2,EVL,DCHS1,VLDLR,DEPTOR,AK4,FGFR1,ISG20,GNAI1,SNCA,GSN,GYPC,SH3BP4,PAM,HPGD,EGFL7,HGF,MLLT3,MEF2C,RRAGD |
| 1.856e-08 | -17.80 | integral component of membrane | cellular component | GO:0016021 | 5248 | 597 | 18223 | 1724 |
GXYLT2,FLVCR2,CNTNAP3,GRIK2,MCOLN3,CADM2,ABHD6,NOS1AP,PCDH7,TGFBR3,FAAH2,TMED9,TMEM37,TSHR,SMIM20,DCC,WLS,TGFA,GJB2,HACD1,ABCC2,KCND3,MFSD6,SLC7A1,ENPP1,ATP7B,ADRB1,TMEFF2,SCN5A,TMEM63C,ITGA6,SLC36A4,BNIP1,FAM189A1,BACE2,CACNB2,FLRT3,LMAN2,ST8SIA1,NCAM1,MOXD1,JAM2,TSPAN9,CHRM3,LRP12,HMGCR,FADS1,SLC37A1,KCNQ3,MGST3,CALCRL,RYR2,ST6GALNAC3,AIG1,SHISA2,SNAP25,OR11H4,CLN5,TMCO3,CACHD1,QPCTL,CDH17,CLMN,LAPTM4B,CDH2,TRPC3,BTC,SCAMP1,GALNT12,GALNT6,ABHD13,PKP2,IL13RA1,NRXN1,SLC19A2,CDS1,GPR15,RNF150,PLPP1,TLR3,CHRNA5,KMO,COL25A1,SYNGR3,FAM155B,KIAA1549,PERP,SCN3A,KCNB2,FZD1,EBPL,RNF145,FZD4,KCNH5,TRAM1L1,ADCY1,PCNX2,PXYLP1,ASPH,FGFR1,GJC1,SLC39A14,ENTPD1,GYPC,GPR160,PEMT,WFS1,PAM,ALG11,TNFSF15,PLD5,SERINC5,TMEM132C,EDA2R,ROBO2,BACE1,FZD8,CD276,BIK,UBAC2,NKAIN2,P2RY1,SLC12A6,EPHB1,ZNF219,KCNC4,TSPAN17,NEO1,LRRN1,GHR,NPTXR,TRPM4,RAPGEF2,ELOVL3,ATP11A,HEG1,PTPRC,GALNT3,PCDHB7,PLPPR2,SRD5A3,OSBPL5,XBP1,SLCO5A1,DCBLD1,ATP2B4,CACNG3,SYT12,LILRB1,ITPR2,MGAT5B,SYT14,KCNN2,TM9SF2,KCNAB1,HPS1,MARVELD2,ITGB3,TMEM86A,TMEM143,TMEM132E,TLR4,ITGB7,CD55,SLC3A2,KCNIP3,GCNT2,ABCC4,GDPD1,NFE2L1,PLPP2,CR2,TMEM200C,PLEKHB1,SPNS1,KCNMB4,INSIG1,ERN1,TNFRSF1A,ADGRA3,ADGRL2,HS6ST3,TYRO3,KCNV1,STXBP5L,MLC1,PGAP1,IL18R1,RNF180,GALNT1,SEMA4F,IGF1R,ABCA5,FRAS1,HS3ST5,LRP6,ADCY6,BNIP3,NIPAL2,PTPRCAP,SLCO4C1,FAR2,CKAP4,TMEM178B,FGFR4,CHSY3,UNC5C,B3GLCT,BTNL9,SLC27A2,RNF170,MGAT4B,EFNA3,TMTC4,SLITRK5,SDK1,GPR19,GRIK4,KCNK15,MFSD2A,CSF1,SLC2A6,RNF122,SMCO4,MME,LPCAT2,XYLT1,RNF24,OR51B4,NTRK3,FAM198B,SLC7A2,SEZ6L2,PRR7,SEMA6A,SLC22A17,ZDHHC6,ZDHHC23,ADGRL1,SCN2A,TMEM56,HRASLS,TMEM67,EVA1A,TMEM65,LRRC8B,CHRNA6,JAM3,NRG3,PTPRJ,RNF217,PTK7,KCNG1,ITGA2,MAOA,PTPRS,SUSD4,MBOAT2,ARFGEF3,RETREG1,TENM1,PCDH18,LPAR2,SLC6A9,BMPR2,MCTP2,SELL,GABRG2,SFXN3,USP30,SLC35F1,TECPR1,FUT9,KCNMB3,TSPAN13,SLC45A3,ATP2B1,FNDC3A,NPDC1,ILDR2,CD37,TMEM237,FAT4,FMO4,DLG2,MYRF,SLC22A15,SLC1A5,PTGES,CACNA2D1,FAM171B,ACVR1,SIDT1,LGR4,ATP8A1,VAMP8,LDLR,SLC9A7,SLC16A2,SLC22A18,SERINC2,NDUFB8,KCNS3,ATRNL1,THSD1,GDAP1,ERGIC1,ACVR1C,SLC9C1,LRMP,BNIP3L,SLC25A28,ACVR2B,ZDHHC14,GPC6,GPR150,SPATA9,SFXN1,NCKAP1L,ENTPD7,B3GALT2,MFSD4A,DSEL,UNC5B,NRP1,EFNB2,LRFN5,SEMA6B,MRC2,ALOX5AP,CELSR1,PTPRD,GABRB2,ST6GAL1,SCN8A,DHCR24,MFSD13A,SLC25A27,SLC1A3,WDFY4,TNFRSF10C,TNFRSF19,PRRG4,MYORG,GAS1,MCOLN2,GBGT1,SLC7A11,MSMO1,OPN3,SCARF2,SREBF1,TSPAN12,SLC16A9,FAM155A,GPR161,IGSF3,RNF152,PTCH2,QSOX1,SLC36A1,DCHS1,VLDLR,KIAA1324L,TTYH2,RABAC1,FAM162A,TMEM74,DAGLA,MMP15,XKR9,PMEPA1,MPP2,SQLE,DHCR7,EPHA3,ELOVL4,TCTN2,RNF144A,ST14,GPR65,PLXNA2,MSR1,CHUK,TMEM170B,DDR1,TMEM53,ERG28,PDE4D,ATP6AP1L,B3GALT1,TMEM43,SFXN4,SHANK2,NLGN4X,ATP1B1,TRIQK,ATP10D,DCBLD2,HTR7,POPDC3,ASIC1,MAP3K21,HS3ST3B1,BMPR1A,DENND5B,ANO10,PLSCR4,ATP9A,GPR180,GABRR2,NDFIP2,SLC35G2,GDPD5,ADGRB2,LRRC55,SOAT2,MGAT1,GPR155,RMDN2,SLC6A15,CERS4,B4GALT6,TMC7,SLC40A1,CACNA1E,AGPAT4,MPP1,TMEM126A,ZDHHC15,GPR137C,OR2T33,CLDN12,PLXDC2,GRIN2D,TNFRSF17,CERS1,OCLN,B4GALT7,SLC43A1,ATP1A3,MPZL3,UGT8,ACSL1,SLC2A13,DNER,CACNB4,SLCO3A1,KREMEN1,CHST10,FKBP11,F3,RTN1,CYP51A1,EPCAM,SLC10A7,CNNM2,TRPC1,SLC2A12,HRK,EPHB6,CTTN,GALNT18,PTPRE,OR2W3,IL1RAP,PDGFRB,LAMP3,ATL1,GPM6A,CEMIP2,JPH1,TMEM47,ROR1,TMEM132B,TMEM150B,GPRC5B,NCAM2,OXTR,TNFSF4,FNDC10,SLC9B1,FRMD5,PCSK5,GPR63,UST,SV2B,SCART1,BVES,STXBP6,ELOVL7,CYP4V2,GALNT13,SCD,CHSY1,CD7,ADGRG6,PCDHB14,SLC30A4,VSIR,NCEH1,RNF148,LRP3,IL17RD,GPR176,CDH26,PCDH10,PODXL2,SLITRK2,SDC3,CATSPERE,GALNT17,B4GALNT3,SLC46A3,STEAP1,HERPUD1,GLCE,TMEM154,ADGRB3,FAT1,NCR3LG1,PTPRN2,TMEM117,DISP2,XKR4,DIRC2,CREB3L2,CXCR5,SORBS1,IL15,CELSR3,CANX,CD53,PDZD8,REEP1,ACVR2A,STEAP3,MET,TMEM120B,HSPA2,SEMA6C,ALG10B,SUSD3,DPP10,ANTXR2,PTPRU,SLC39A8,C3orf52,AMIGO1,SYNJ2BP,CD40,TMPRSS9,CYP2U1,RNF130,DISP1,LIFR,OR51B5,TSPAN15,CLGN,CMTM8,LRP4,TNFSF13B,CLSTN2,FAM174B,SEL1L3,MCU,KCNJ4,SCN1B,LHFPL6,DSG2,KIAA0319,MARCH3,TNFRSF11A,CRIM1,SYBU,GRID1,PRRG1,GALNT14,TLR6,NAALADL2,LRAT,LEPR,DPY19L2,GPR37,MYADM,MFSD9,EDA,ACER2,THSD7B,SLC7A5,SLC18B1,IL9R,MMP16,SLC16A10,ABCG1,STOM,SNPH |
| 1.865e-08 | -17.80 | GSE22886_NEUTROPHIL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NEUTROPHIL_VS_MONOCYTE_UP | 178 | 43 | 17377 | 1707 |
GPR63,TFCP2L1,NECAB2,GRIK2,RECK,MCTP2,OPHN1,TJP1,OVOL2,TNFRSF10C,EPHB1,CBLN1,HOPX,RAB11FIP5,LGI2,SLC22A17,BACE2,FRAS1,MCF2L,LHX6,MAGEA3,KIAA1614,CTTN,MAGEA6,ETV1,RIMS2,MID2,COL4A3,MYO10,EFHC2,OGDHL,NLGN4X,GPLD1,PTPRJ,MAP2,PLOD2,ITGA2,TUFT1,TTC39A,LIFR,IL9R,FOXA1,MME |
| 1.995e-08 | -17.73 | cell cortex | cellular component | GO:0005938 | 294 | 59 | 18223 | 1724 |
RHOBTB1,RHOD,STXBP6,EPS8,ITPR2,GPSM2,SPINK5,PCLO,PPP1R9A,HMCN1,NEDD4,SPIRE1,SCIN,RND2,UNC13B,FRY,CNKSR3,RTKN2,MARCKS,IPCEF1,CTTN,MYO6,SEPT3,MYRIP,ENO1,RIMS2,DBN1,PHLDB2,FER,USP2,PXN,RHOQ,MYO10,MPP1,DSTN,EXOC6B,PARD3B,CAP2,CRIP2,GPSM1,FERMT2,HIP1,PLS1,ARHGAP32,ASPH,GNAI1,SNCA,GSN,PLEKHH2,MYADM,GYPC,RND3,WIPF3,RAI14,SEPT5,FNBP1L,CTTNBP2,CDH2,COBL |
| 2.004e-08 | -17.73 | regulation of actin filament-based process | biological process | GO:0032970 | 376 | 71 | 17256 | 1658 |
EPHA3,PRKN,ID1,FGF13,TMSB15A,RHOD,GPR65,PKP2,ADD2,NTRK3,RAC3,PPP1R9A,NOS1AP,SCIN,RND2,ARHGEF10L,PPM1E,PDE4D,CTTN,MET,SLIT2,NEB,PDGFRB,PHLDB2,FER,SSH3,EVL,MYLK3,DSTN,ANK2,PREX1,WNT11,DSP,JAM3,SMAD3,GSN,WIPF3,NCKAP1L,PAM,ARHGAP28,TMOD2,TPM1,TMEFF2,NRP1,MEF2C,TENM1,SCN5A,CELSR1,RHOBTB1,EPS8,SORBS3,PFN2,SPIRE1,FHOD3,ARHGAP44,PRKCD,DSG2,SH3PXD2B,FES,TRPM4,PAK1,SYNPO2,RHOQ,PXN,ASAP3,RYR2,BAIAP2,PLEKHH2,MYADM,RND3,CTSV |
| 2.004e-08 | -17.73 | receptor complex | cellular component | GO:0043235 | 374 | 70 | 18223 | 1724 |
EPHA3,SORBS1,CACNG3,ACVR1,GRIK2,LDLR,PLXNA2,CHUK,IL13RA1,NTRK3,ITPR2,DDR1,ABHD6,TGFBR3,CHRNA5,ITGB3,TRPC1,ACVR2A,EPHB6,MET,TLR4,TSHR,PDGFRB,ITGB7,ACVR1C,PTPN6,SHANK2,CR2,CHRNA6,ACVR2B,ROR1,CD40,FGFR1,AHRR,SMAD3,GPR160,ITGA2,MAP3K21,TNFRSF1A,BMPR1A,NRP1,NR3C2,LIFR,GPR63,TYRO3,GABRB2,ITGA6,LRP4,GABRG2,GABRR2,EPHB1,IGF1R,GHR,LRP6,LOXL4,GFRA1,SYK,FGFR4,VLDLR,SLITRK5,CALCRL,PEX5L,SKAP1,TLR6,LEPR,GPR37,GRIK4,PTPRN2,DLG2,GRIN2D |
| 2.007e-08 | -17.72 | kidney-carcinoma-papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-papillary_renal_cell_carcinoma | 6518 | 742 | 17385 | 1698 |
ARHGAP26,GXYLT2,FLVCR2,AASS,CNTNAP3,MCOLN3,CEBPA,CADM2,BCAN,NHP2,KIAA1217,SNX9,CA8,ABHD6,EYA4,TXNDC5,IKZF5,DNAH6,PPFIA2,RAP2A,RAB26,CPE,DCC,TGFA,LRRK2,NFIA,PRKAR2B,ABCC2,F12,CA13,SLC7A1,ENPP1,ZNF266,WIPF3,ATP7B,ZBTB20,DNHD1,GNG12,LATS2,ITGA6,TJP1,SLC36A4,GPSM2,BBS9,TTC30B,GRPEL2,FRY,BACE2,SRGAP1,CADPS2,ALPK1,FIGN,NCAM1,MOXD1,AGL,GLIS1,STXBP1,FMNL2,CHRM3,ZNF385A,FADS1,SLC37A1,PNP,MYO10,SPATA6,ARID5B,FASN,RYR2,HIP1,CALCRL,SHISA2,ZBBX,TAF4B,C11orf45,CACHD1,TEX15,ADAMTS3,EMILIN2,CDH17,CLMN,TRPC3,DOCK9,MTG1,TFCP2L1,BTC,NUDT10,DNM3,ZNF516,GALNT6,LRRCC1,ABHD13,BEGAIN,PKP2,GRK6,COLEC10,LCP2,NRXN1,SLC19A2,RNF150,EPB41L3,TLR3,CHRNA5,CNKSR3,ALDH1L1,PJA1,FAM155B,RPL26L1,DNAH5,SNX10,MYT1,ANKRD18B,SCN3A,DOCK8,FZD1,DZANK1,MYLK3,COL6A2,EBPL,FZD4,KCNH5,ADCY1,RAB38,TTC28,DSP,ASPH,METAP1D,FGFR1,GJC1,ARHGAP21,WFS1,LAMB1,INPP4B,PAM,PLEKHG1,P4HA1,TNFSF15,FAM149A,KLHL31,HOXB9,FARP1,TMEM132C,WDR17,ROBO2,CKAP2,BACE1,BIK,IPO5,UBAC2,PSD3,P2RY1,PKN1,EPHB1,KCNC4,COL27A1,NEO1,PCBP4,MYO6,C15orf41,MED12L,FES,ULBP1,TRPM4,MN1,MCF2L2,RAPGEF2,ATP11A,SNTB1,HEG1,PTPRC,TRIB3,NSD1,RPL12,PCDHB7,PLOD2,AKT3,OSBPL5,NEK11,PIP5KL1,HK1,DOCK6,FOXA1,TLL2,TPT1,TRIM2,FAM227A,FHDC1,ASS1,LILRB1,MGAT5B,ITPR2,SYT14,FAM13A,FSTL5,PLS3,RND2,RUFY4,RPS6KA2,CPVL,SEC16B,KCNN2,HPS1,ITGB3,COL19A1,JAKMIP2,KIAA1614,TLN2,TMEM132E,TLR4,ETV1,NEB,DBN1,ITGB7,MARK1,KCNIP3,ABCC4,PNRC1,COL4A3,ANK2,CR2,TCERG1L,CRYBG3,NT5DC2,SPNS1,DYRK1B,TRIM9,TCF7L1,INHBC,P4HA2,TECPR2,ERN1,TIGD4,AHNAK2,PIK3C2B,MLLT3,PRKAA2,RUNX2,LGALS3,STXBP5L,SETBP1,ZIC2,PGAP1,FHOD3,KIAA0895,ZBTB38,IGF1R,SEMA4F,ABCA5,GAN,SMTN,LRP6,ADCY6,FAR2,NIPAL2,FBXL2,VGLL4,PAK1,FGFR4,CHSY3,SLC27A2,TMTC4,SPATA13,PPFIA4,STRADB,OBSCN,SDK1,MAPKAPK2,GRIK4,KCNK15,ATPAF2,SLC2A6,PLD1,SEMA3A,PANK3,MME,SFN,ID1,CFH,DOCK1,RBFOX2,XYLT1,RHPN2,NTRK3,SLC7A2,FAM198B,KIF21B,SEZ6L2,DENND3,FAM110B,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,CYP26A1,TBC1D19,TACC2,MYO3B,MYH15,SCN2A,SNAI2,CTH,GLI1,INTU,TMEM67,TDRD3,LRRC8B,THSD4,ACO1,FGF12,VIM,FRK,C4BPB,SMAD3,IFT81,RANBP2,NRG3,PTPRJ,PTK7,GBP1,ITGA2,ABI3,KCNG1,PTPRS,SUSD4,CTNND2,CNTN1,TENM1,COL9A3,DYRK3,LPAR2,SLC6A9,BMPR2,RUSC2,MCTP2,SELL,USP30,PPP2R3A,FOXP2,TECPR1,MAP1A,TFAP2A,SGK1,PRICKLE2,PCK2,ESD,SYK,KIAA1211,ATP2B1,CES3,DLGAP1,LRRIQ1,NUAK2,PRICKLE1,FERMT2,PALLD,ILDR2,DOCK7,FAT4,FBN1,FMO4,ZNF808,ZNF474,TBC1D4,KIF1B,CACNA2D1,FILIP1,ZNF235,MYCBP2,CGN,ACVR1,PPP4R4,TTC39B,TCP11L2,LGR4,LDLR,PPFIBP2,PRKCA,AARS,STK24,SLC9A7,SLC22A18,SERINC2,KCNS3,ATRNL1,BEND4,MAGEA6,THSD1,PLTP,TBC1D8,GLDC,GDAP1,EML6,ACVR1C,KLHL3,KLHL4,ALDH1L2,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,GPC6,GPR150,GNAI1,AHRR,SPATA9,SH3RF1,NCKAP1L,PLK2,ENTPD7,MAPK13,DSEL,UNC5B,TANC2,LZTS1,SPOCK3,EFNB2,LRFN5,MRC2,INPPL1,CELSR1,EHHADH,PTPRD,SCN8A,GABRB2,DHCR24,OLAH,MRPL22,GTF2IRD1,LRRC49,WDFY4,DYNC1I1,TNFRSF19,NIPSNAP3B,MTUS1,ABLIM1,NAV1,ADCK1,NOVA2,PDZD7,VWDE,SREBF1,PRKG1,CPXM2,SLC16A9,SAMD13,PRR16,RNF152,IGSF3,RPL26,TBC1D8B,PLEKHA8,COL4A4,RAPGEF4,DCHS1,NPC2,CCDC85A,RABAC1,CDC42BPA,PLCB1,FAM162A,ZNF558,MMP15,PLEKHH2,PKN3,PMEPA1,CECR2,C1orf21,MATN2,SFMBT1,IQSEC2,AMPD1,ACSM3,FRMPD3,EPHA3,AMOTL1,ST14,GPR65,CCDC110,PLXNA2,OTX1,MSR1,CHUK,TMEM170B,DDR1,COL14A1,ZFYVE9,NELL2,SPEG,TMEM53,ZNF438,ALDOC,SHF,NBEA,DAB2IP,GAB2,PDK1,TMEM43,PREX1,NLGN4X,SATB2,ATF3,PRKCQ,CBY1,ATP1B1,ATP10D,DCBLD2,IKZF3,PRKCB,GRB10,KLF5,BMPR1A,CTTNBP2,NR3C2,STON2,HACE1,DENND5B,ANO10,MYO1D,ANKRD13D,EPS8,PRSS35,HERC5,KIF5C,ARL2,GPR180,RGS7,RASSF8,RGS17,LRRC55,GPR155,SGK3,RALGAPA2,SLC6A15,DYNC2H1,FIG4,TBC1D9,GFI1,SPRY2,PFKFB4,TMC7,SLC40A1,ARHGEF28,ALDH2,ARAP2,SYNPO2,CACNA1E,MPP1,PTPN13,CTTNBP2NL,SKAP1,GPR137C,HOXA1,ZIC1,GPLD1,FGR,TERT,PLXDC2,CLDN12,NUTM2A,MCC,TUFT1,SVIL,MYOM2,LARP1,SLC43A1,ATP1A3,EXPH5,ACSL1,KIF5A,HEBP1,UGDH,ANKRD18A,SLC2A13,RBM11,IKZF2,HMCN1,SLCO3A1,CEP85L,FKBP11,ARHGEF10L,SIPA1L2,GRHL1,ABI3BP,CNNM2,SLC2A12,SLIT2,PRKACB,PDGFRB,RASGRP1,CYP1B1,TNK2,SKAP2,CAPN5,JPH1,YAP1,ROR1,SGK2,GSN,HPSE,NCAM2,OXTR,PPARGC1A,APBA2,MAGI2,SV2B,ZNF395,FN1,RHOBTB1,BVES,LAMC3,CHADL,SPINK5,SATB1,PCDHB14,ZNF629,CDH26,IL17RD,PODXL2,SLITRK2,MSTN,SDC3,WWC1,B4GALNT3,SLC46A3,AMDHD1,HERPUD1,GLCE,KIAA0355,FCHO2,FAT1,RAI14,RAB31,SH3BP4,PTPRN2,EGFL7,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,ARHGAP22,HECW2,MORC4,COL18A1,BCL6B,UBTD2,DOCK2,CD53,SCIN,COL22A1,PDZD8,UNC13B,RPS6KL1,PPFIBP1,ZNF521,ACVR2A,PROS1,WWC2,MET,TMEM120B,HSPA2,NTNG1,SEMA6C,SP140L,ALG10B,DPP10,FER,GCA,SLC39A8,TTLL7,DOCK5,TPK1,ZNF569,ARMC4,ZNF93,LMLN,BACH2,TMPRSS9,LIFR,MAST1,TNIK,PRSS16,TSPAN15,LRP4,SSX1,COL4A5,IGF2BP2,NOTUM,CUEDC2,SEL1L3,BMP6,SYDE2,FSD1,KCNJ4,CHN2,GTSF1,PRKCD,DSG2,KIAA0319,TRIM3,AFAP1L2,IPCEF1,PNMA2,RIN2,CARD6,HNF4G,GRID1,ASAP3,MEI1,PRRG1,MARS,AGAP2,ARHGAP32,GALNT14,MAP1B,RERE,GPR37,DPY19L2,ADAMTS17,TIFA,MFSD9,MYADM,RND3,ACER2,PRCP,MAP2K6,THSD7B,UACA,KIAA0513,KIF21A,GEM,RNF157,NPHP1,SLC16A10,SNPH |
| 2.007e-08 | -17.72 | papillary_renal_cell_carcinoma | COSMIC cancer mutations | papillary_renal_cell_carcinoma | 6518 | 742 | 17385 | 1698 |
ARHGAP26,GXYLT2,FLVCR2,AASS,CNTNAP3,MCOLN3,CEBPA,CADM2,BCAN,NHP2,KIAA1217,SNX9,CA8,ABHD6,EYA4,TXNDC5,IKZF5,DNAH6,PPFIA2,RAP2A,RAB26,CPE,DCC,TGFA,LRRK2,NFIA,PRKAR2B,ABCC2,F12,CA13,SLC7A1,ENPP1,ZNF266,WIPF3,ATP7B,ZBTB20,DNHD1,GNG12,LATS2,ITGA6,TJP1,SLC36A4,GPSM2,BBS9,TTC30B,GRPEL2,FRY,BACE2,SRGAP1,CADPS2,ALPK1,FIGN,NCAM1,MOXD1,AGL,GLIS1,STXBP1,FMNL2,CHRM3,ZNF385A,FADS1,SLC37A1,PNP,MYO10,SPATA6,ARID5B,FASN,RYR2,HIP1,CALCRL,SHISA2,ZBBX,TAF4B,C11orf45,CACHD1,TEX15,ADAMTS3,EMILIN2,CDH17,CLMN,TRPC3,DOCK9,MTG1,TFCP2L1,BTC,NUDT10,DNM3,ZNF516,GALNT6,LRRCC1,ABHD13,BEGAIN,PKP2,GRK6,COLEC10,LCP2,NRXN1,SLC19A2,RNF150,EPB41L3,TLR3,CHRNA5,CNKSR3,ALDH1L1,PJA1,FAM155B,RPL26L1,DNAH5,SNX10,MYT1,ANKRD18B,SCN3A,DOCK8,FZD1,DZANK1,MYLK3,COL6A2,EBPL,FZD4,KCNH5,ADCY1,RAB38,TTC28,DSP,ASPH,METAP1D,FGFR1,GJC1,ARHGAP21,WFS1,LAMB1,INPP4B,PAM,PLEKHG1,P4HA1,TNFSF15,FAM149A,KLHL31,HOXB9,FARP1,TMEM132C,WDR17,ROBO2,CKAP2,BACE1,BIK,IPO5,UBAC2,PSD3,P2RY1,PKN1,EPHB1,KCNC4,COL27A1,NEO1,PCBP4,MYO6,C15orf41,MED12L,FES,ULBP1,TRPM4,MN1,MCF2L2,RAPGEF2,ATP11A,SNTB1,HEG1,PTPRC,TRIB3,NSD1,RPL12,PCDHB7,PLOD2,AKT3,OSBPL5,NEK11,PIP5KL1,HK1,DOCK6,FOXA1,TLL2,TPT1,TRIM2,FAM227A,FHDC1,ASS1,LILRB1,MGAT5B,ITPR2,SYT14,FAM13A,FSTL5,PLS3,RND2,RUFY4,RPS6KA2,CPVL,SEC16B,KCNN2,HPS1,ITGB3,COL19A1,JAKMIP2,KIAA1614,TLN2,TMEM132E,TLR4,ETV1,NEB,DBN1,ITGB7,MARK1,KCNIP3,ABCC4,PNRC1,COL4A3,ANK2,CR2,TCERG1L,CRYBG3,NT5DC2,SPNS1,DYRK1B,TRIM9,TCF7L1,INHBC,P4HA2,TECPR2,ERN1,TIGD4,AHNAK2,PIK3C2B,MLLT3,PRKAA2,RUNX2,LGALS3,STXBP5L,SETBP1,ZIC2,PGAP1,FHOD3,KIAA0895,ZBTB38,IGF1R,SEMA4F,ABCA5,GAN,SMTN,LRP6,ADCY6,FAR2,NIPAL2,FBXL2,VGLL4,PAK1,FGFR4,CHSY3,SLC27A2,TMTC4,SPATA13,PPFIA4,STRADB,OBSCN,SDK1,MAPKAPK2,GRIK4,KCNK15,ATPAF2,SLC2A6,PLD1,SEMA3A,PANK3,MME,SFN,ID1,CFH,DOCK1,RBFOX2,XYLT1,RHPN2,NTRK3,SLC7A2,FAM198B,KIF21B,SEZ6L2,DENND3,FAM110B,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,CYP26A1,TBC1D19,TACC2,MYO3B,MYH15,SCN2A,SNAI2,CTH,GLI1,INTU,TMEM67,TDRD3,LRRC8B,THSD4,ACO1,FGF12,VIM,FRK,C4BPB,SMAD3,IFT81,RANBP2,NRG3,PTPRJ,PTK7,GBP1,ITGA2,ABI3,KCNG1,PTPRS,SUSD4,CTNND2,CNTN1,TENM1,COL9A3,DYRK3,LPAR2,SLC6A9,BMPR2,RUSC2,MCTP2,SELL,USP30,PPP2R3A,FOXP2,TECPR1,MAP1A,TFAP2A,SGK1,PRICKLE2,PCK2,ESD,SYK,KIAA1211,ATP2B1,CES3,DLGAP1,LRRIQ1,NUAK2,PRICKLE1,FERMT2,PALLD,ILDR2,DOCK7,FAT4,FBN1,FMO4,ZNF808,ZNF474,TBC1D4,KIF1B,CACNA2D1,FILIP1,ZNF235,MYCBP2,CGN,ACVR1,PPP4R4,TTC39B,TCP11L2,LGR4,LDLR,PPFIBP2,PRKCA,AARS,STK24,SLC9A7,SLC22A18,SERINC2,KCNS3,ATRNL1,BEND4,MAGEA6,THSD1,PLTP,TBC1D8,GLDC,GDAP1,EML6,ACVR1C,KLHL3,KLHL4,ALDH1L2,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,GPC6,GPR150,GNAI1,AHRR,SPATA9,SH3RF1,NCKAP1L,PLK2,ENTPD7,MAPK13,DSEL,UNC5B,TANC2,LZTS1,SPOCK3,EFNB2,LRFN5,MRC2,INPPL1,CELSR1,EHHADH,PTPRD,SCN8A,GABRB2,DHCR24,OLAH,MRPL22,GTF2IRD1,LRRC49,WDFY4,DYNC1I1,TNFRSF19,NIPSNAP3B,MTUS1,ABLIM1,NAV1,ADCK1,NOVA2,PDZD7,VWDE,SREBF1,PRKG1,CPXM2,SLC16A9,SAMD13,PRR16,RNF152,IGSF3,RPL26,TBC1D8B,PLEKHA8,COL4A4,RAPGEF4,DCHS1,NPC2,CCDC85A,RABAC1,CDC42BPA,PLCB1,FAM162A,ZNF558,MMP15,PLEKHH2,PKN3,PMEPA1,CECR2,C1orf21,MATN2,SFMBT1,IQSEC2,AMPD1,ACSM3,FRMPD3,EPHA3,AMOTL1,ST14,GPR65,CCDC110,PLXNA2,OTX1,MSR1,CHUK,TMEM170B,DDR1,COL14A1,ZFYVE9,NELL2,SPEG,TMEM53,ZNF438,ALDOC,SHF,NBEA,DAB2IP,GAB2,PDK1,TMEM43,PREX1,NLGN4X,SATB2,ATF3,PRKCQ,CBY1,ATP1B1,ATP10D,DCBLD2,IKZF3,PRKCB,GRB10,KLF5,BMPR1A,CTTNBP2,NR3C2,STON2,HACE1,DENND5B,ANO10,MYO1D,ANKRD13D,EPS8,PRSS35,HERC5,KIF5C,ARL2,GPR180,RGS7,RASSF8,RGS17,LRRC55,GPR155,SGK3,RALGAPA2,SLC6A15,DYNC2H1,FIG4,TBC1D9,GFI1,SPRY2,PFKFB4,TMC7,SLC40A1,ARHGEF28,ALDH2,ARAP2,SYNPO2,CACNA1E,MPP1,PTPN13,CTTNBP2NL,SKAP1,GPR137C,HOXA1,ZIC1,GPLD1,FGR,TERT,PLXDC2,CLDN12,NUTM2A,MCC,TUFT1,SVIL,MYOM2,LARP1,SLC43A1,ATP1A3,EXPH5,ACSL1,KIF5A,HEBP1,UGDH,ANKRD18A,SLC2A13,RBM11,IKZF2,HMCN1,SLCO3A1,CEP85L,FKBP11,ARHGEF10L,SIPA1L2,GRHL1,ABI3BP,CNNM2,SLC2A12,SLIT2,PRKACB,PDGFRB,RASGRP1,CYP1B1,TNK2,SKAP2,CAPN5,JPH1,YAP1,ROR1,SGK2,GSN,HPSE,NCAM2,OXTR,PPARGC1A,APBA2,MAGI2,SV2B,ZNF395,FN1,RHOBTB1,BVES,LAMC3,CHADL,SPINK5,SATB1,PCDHB14,ZNF629,CDH26,IL17RD,PODXL2,SLITRK2,MSTN,SDC3,WWC1,B4GALNT3,SLC46A3,AMDHD1,HERPUD1,GLCE,KIAA0355,FCHO2,FAT1,RAI14,RAB31,SH3BP4,PTPRN2,EGFL7,DISP2,FNBP1L,OSBPL6,XKR4,DMXL2,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,ARHGAP22,HECW2,MORC4,COL18A1,BCL6B,UBTD2,DOCK2,CD53,SCIN,COL22A1,PDZD8,UNC13B,RPS6KL1,PPFIBP1,ZNF521,ACVR2A,PROS1,WWC2,MET,TMEM120B,HSPA2,NTNG1,SEMA6C,SP140L,ALG10B,DPP10,FER,GCA,SLC39A8,TTLL7,DOCK5,TPK1,ZNF569,ARMC4,ZNF93,LMLN,BACH2,TMPRSS9,LIFR,MAST1,TNIK,PRSS16,TSPAN15,LRP4,SSX1,COL4A5,IGF2BP2,NOTUM,CUEDC2,SEL1L3,BMP6,SYDE2,FSD1,KCNJ4,CHN2,GTSF1,PRKCD,DSG2,KIAA0319,TRIM3,AFAP1L2,IPCEF1,PNMA2,RIN2,CARD6,HNF4G,GRID1,ASAP3,MEI1,PRRG1,MARS,AGAP2,ARHGAP32,GALNT14,MAP1B,RERE,GPR37,DPY19L2,ADAMTS17,TIFA,MFSD9,MYADM,RND3,ACER2,PRCP,MAP2K6,THSD7B,UACA,KIAA0513,KIF21A,GEM,RNF157,NPHP1,SLC16A10,SNPH |
| 2.025e-08 | -17.71 | liver-carcinoma | COSMIC cancer mutations | liver-carcinoma | 15799 | 1602 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,SPIRE1,FHOD3,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,OBSCN,SDK1,KHDRBS2,GPR19,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,TNK2,SESN2,SKAP2,JPH1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,TMEFF2,MEF2C,CRYL1,CARS,LATS2,STOX2,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,AVPI1,CFH,LPCAT2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,RAC3,AARS,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,LINC00896,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,WASF3,ANO10,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 2.094e-08 | -17.68 | chr5q35 | MSigDB lists | chr5q35 | 96 | 29 | 17377 | 1707 |
DBN1,PDLIM7,ERGIC1,BTNL9,MGAT4B,NPM1,GRK6,NHP2,CANX,RNF44,PRR7,DOCK2,TSPAN17,SFXN1,ZFP62,NSD1,GPRIN1,ZNF354A,MGAT1,STC2,PRELID1,LMAN2,TMED9,SH3PXD2B,RNF130,RPL26L1,B4GALT7,THOC3,BOD1 |
| 2.188e-08 | -17.64 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE | 75 | 25 | 17377 | 1707 |
FADS1,RIN2,SLC3A2,GARS,MVK,PNP,LDLR,GTF2IRD1,MARS,SCD,CANX,SNX9,BMP6,CYP51A1,INSIG1,MSMO1,TERT,MYC,ALDOC,PAM,HK2,SQLE,CTH,TBC1D8,HMGCR |
| 2.226e-08 | -17.62 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | 179 | 43 | 17377 | 1707 |
GPT2,AVPI1,ENO2,SCAMP1,GCAT,ST6GAL1,GATA3,PKP2,CHAC1,NIPSNAP3B,NEDD4,PPP2R3A,DDIT4,PPP1R26,ALDOC,REEP1,MYO6,ENO1,SNX10,CTH,MID2,ANTXR2,PHLDB2,SLC3A2,GARS,PDK1,ALDH1L2,VLDLR,ATF3,VIM,PRDM1,CRYBG3,BATF3,TRIB3,IFT81,HPSE,MFSD2A,P4HA2,EIF4EBP1,UACA,HK1,BMPR1A,MBOAT2 |
| 2.375e-08 | -17.56 | pancreas-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-ductal_carcinoma | 16044 | 1621 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH,STOM |
| 2.448e-08 | -17.53 | central nervous system development | biological process | GO:0007417 | 899 | 137 | 17256 | 1658 |
UGT8,FGF13,NDRG2,ABAT,BCAN,DNER,AARS,RAC3,SKI,BAG3,EOMES,KCNAB1,SLIT2,POU3F3,NKX2-1,SMAD9,DCC,WLS,LRRK2,FEZ1,EFHC1,ROR1,EML1,TSKU,GSN,MAP2,GNB4,SERPINI1,DLX2,OXTR,NRP1,PPARGC1A,TYRO3,BCL11B,SCN5A,GNG12,CELSR1,OPHN1,LAMC3,ZIC2,PHGDH,FOXG1,CHD5,HPCAL4,PGAP1,DDIT4,NUMBL,CNTN4,SLC7A11,GATA2,PRKG1,LRP6,BNIP3,FGFR4,PAK1,RAX,UNC5C,VLDLR,SLITRK5,MAFB,CLN5,PLCB1,BAIAP2,SH3GL2,MFSD2A,CDH2,SEMA3A,PRKN,ID1,RBFOX2,PLXNA2,OTX1,CBLN1,CTNNA2,RIDA,TACC2,LHX6,DAB2IP,SYNGR3,ZNF365,ZNF488,FZD1,GLI1,INTU,FZD4,SHANK2,ADCY1,NLGN4X,VIM,SATB2,ATOH1,AMIGO1,FGFR1,ARMC4,IRS2,NRG3,LAMB1,PAM,PTPRS,BMPR1A,CTTNBP2,CNTN1,MYO1D,PCDH18,WASF3,ROBO2,BMPR2,PRDM8,EPHB1,SELENOP,GDPD5,NKX6-1,KDM7A,FOXP2,HMGCS1,SCN1B,AFF2,TFAP2A,DYNC2H1,ATP2B1,MSX1,RAPGEF2,AK4,ZIC1,RERE,DKK1,ID3,DOCK7,FAT4,AKT3,GNAO1,GRIN2D,BMP4,MYRF,JHY,ATP2B4,SNPH |
| 2.467e-08 | -17.52 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 16307 | 1641 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,OR11H4,TAF4B,MBNL2,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,CACNB4,IKZF2,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 2.639e-08 | -17.45 | GO_CELL_PROJECTION | MSigDB lists | GO_CELL_PROJECTION | 1693 | 233 | 17377 | 1707 |
DOC2A,FGF13,PRSS12,GRIK2,KIF5A,ASS1,NDRG2,ENAH,CADM2,ABAT,BCAN,DNER,SNX9,RAC3,NCS1,PLS3,TUBB4A,BAG3,LRRC6,KCNAB1,KCNN2,DNAH6,ITGB3,GSTM3,LIN7A,CTTN,PACSIN1,TLN2,MYRIP,PRKACB,DBN1,ATL1,GPM6A,ATF4,KCNIP3,DCC,WLS,CAP2,ANK2,DNAJC6,LRRK2,FEZ1,EFHC1,PRKAR2B,PLEKHA1,KCND3,ARHGEF26,TRIM9,AK1,GSN,NCAM2,MAP2,SH3RF1,PLK2,TMOD2,OXTR,SPRY4,PPARGC1A,NRP1,TPM1,MAGI2,LZTS1,BCL11B,INPPL1,BVES,SCN8A,OPHN1,SLC1A3,APBA1,BBS9,PFN2,TTC30B,ABLIM1,CA2,CNTN4,PDZD7,FLRT3,GRIP1,ADCY6,MPDZ,BNIP3,STXBP1,CHRM3,GPR161,ZNF385A,EPB41L5,PAK1,DPYSL5,UNC5C,DISC1,KCNQ3,MYO10,SPATA6,HOMER2,SPATA13,WWC1,TTC30A,SDC3,SNAP25,CPEB1,SPATA7,BAIAP2,DAGLA,PLEKHH2,RPL28,FAT1,WDR19,DYNC2LI1,PTPRN2,CDH2,SEMA3A,TESC,MME,AMOTL1,DNM3,TCTN2,AKAP5,MYO1B,ADD2,CANX,NRXN1,TBC1D30,SEMA6A,PPP1R9A,CTNNA2,TIAM2,CCDC120,NELL2,EPB41L3,UNC13B,CHRNA5,GPRIN1,DAB2IP,MARCKS,SCN2A,DNAH5,KCNB2,SCN3A,GLI1,FZD1,FER,TMEM67,EVL,GARS,SHANK2,PREX1,NLGN4X,GSTO1,VIM,AMIGO1,TTLL7,GABARAPL1,SNCA,SLC39A14,CAMK2N1,ARMC4,IFT81,PTPRJ,PEMT,WFS1,ABI3,ITGA2,PAM,BMPR1A,ATG5,SEPT5,CTTNBP2,STON2,COBL,PSPH,CTNND2,WASF3,MYO1D,FARP1,ROBO2,BMPR2,GLIPR1L1,BACE1,LRP4,APBB1,EPS8,CLSTN2,ARL2,GABRG2,KIF5C,P2RY1,EPHB1,GDPD5,KCNC4,NEDD4,ARHGAP44,RGS17,KCNJ4,SCN1B,EHD3,SGK1,ACTA2,SH3PXD2B,DYNC2H1,MYO6,SPRY2,ATP2B1,DLGAP1,B9D1,PDLIM7,LCA5,PXN,MPP1,RAPGEF2,PTPN13,CYTH3,ASAP3,FERMT2,ARHGAP32,PALLD,MAP1B,FGR,DOCK7,ICA1,MYADM,TMEM237,GNAO1,MCC,SVIL,DLG2,PIP5KL1,HK1,KIF1B,NPHP1,FOXA1,ATP2B4,SNPH,ATP1A3 |
| 2.921e-08 | -17.35 | PDZ | smart domains | SM00228 | 145 | 40 | 9493 | 1056 |
FRMPD3,ARHGEF11,RHPN2,TJP1,APBA1,RADIL,PPP1R9A,PCLO,TIAM2,SIPA1L2,PDZD8,PDZD7,CNKSR3,GRIP1,LIN7A,MPDZ,MAST4,RIMS2,PDLIM7,INTU,SYNPO2,PARD3B,RAPGEF2,PTPN13,MPP1,SHANK2,DEPTOR,PREX1,SYNJ2BP,SNTB1,MAGI3,ARHGAP21,PDLIM3,MPP7,AHNAK2,MPP2,DLG2,MAGI2,APBA2,MAST1 |
| 2.958e-08 | -17.34 | MCLACHLAN_DENTAL_CARIES_DN | MSigDB lists | MCLACHLAN_DENTAL_CARIES_DN | 76 | 25 | 17377 | 1707 |
GPM6A,TRIM2,LGR4,ATP9A,KIF5C,ISYNA1,NRXN1,SESN1,PGAP1,FGFR1,GLCE,GPR37,ABLIM1,CA2,PDZD8,PLK2,GHR,MPPED2,TRPC1,NAP1L3,ST8SIA1,MAGI2,CPE,SPOCK3,SLIT2 |
| 2.968e-08 | -17.33 | GSE20366_TREG_VS_TCONV_UP | MSigDB lists | GSE20366_TREG_VS_TCONV_UP | 187 | 44 | 17377 | 1707 |
PRKAA2,GPT2,GNG12,DYRK3,ENO2,SCAMP1,RHOBTB1,GATA3,ADAMTS6,NRN1,IKZF2,TBC1D30,ZFYVE9,GPR15,ADPRHL1,KIAA1958,SEC16B,PDE10A,RAP2A,MYO3B,DAB2IP,SLC16A9,JAKMIP2,FAR2,RIN2,PFKFB2,TRAM1L1,ZDHHC15,PRICKLE1,YAP1,C3orf70,SMAD3,PLAGL1,GPR160,GNB4,MATN2,EMILIN2,INPP5F,OXTR,ATG5,NRP1,SUSD4,CRISPLD1,FRMD5 |
| 2.991e-08 | -17.33 | TGGTGCT,MIR-29A,MIR-29B,MIR-29C | MSigDB lists | TGGTGCT,MIR-29A,MIR-29B,MIR-29C | 482 | 86 | 17377 | 1707 |
EPHA3,EML5,DNM3,ELOVL4,SIDT1,LSM11,ADAMTS6,ABHD4,HMCN1,FAM131B,SKI,LGI2,PPM1E,ZNF362,KCTD15,HPS1,TMEM86A,COL19A1,ACVR2A,TMED9,NAP1L3,DAB2IP,POU2F2,IL1RAP,PDGFRB,COL4A3,TMEM65,NFIA,PLEKHA1,ATP1B1,ASPH,BCL11A,HTR7,KLF12,BACH2,INSIG1,TNFRSF1A,BMP1,HS3ST3B1,OXTR,TPM1,VASH2,PPARGC1A,PURG,RAB30,BCL11B,GNG12,ANKRD13B,CD276,PLAG1,MLF1,YPEL2,COL4A5,CREB5,CHSY1,PGAP1,HMGCS1,NAV1,FRAS1,PRICKLE2,SGK1,LOXL4,ATP2B1,MED12L,HMGCR,PPP1R3D,BCL7A,HNF4G,RAB6B,AGPAT4,COL4A4,MGAT4B,TTYH2,MAFB,FERMT2,ARRDC4,BAIAP2,GPR37,RND3,KIAA0355,FBN1,AKT3,XKR4,ATP2B4,CRISPLD1,PHC1 |
| 2.997e-08 | -17.32 | glioma | COSMIC cancer mutations | glioma | 16557 | 1659 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH,STOM |
| 3.019e-08 | -17.32 | cytoskeletal protein binding | molecular function | GO:0008092 | 897 | 138 | 17224 | 1680 |
PHACTR3,CGN,FGF13,KIF5A,HDGFL3,ENAH,PLS3,KCNN2,POF1B,JAKMIP2,PACSIN1,TLN2,RCAN3,MYRIP,NEB,DBN1,EML6,DCDC1,KLHL3,CAP2,ANK2,KLHL4,DSTN,LRRK2,FEZ1,EFHC1,TNS1,COTL1,EML1,GSN,WIPF3,MAP2,CCDC181,MAP9,ALDOA,TMOD2,TPM1,PPARGC1A,LZTS1,FRMD5,SCN5A,INPPL1,OPHN1,SORBS3,ADSSL1,DYNC1I1,PFN2,FHOD3,SPIRE1,MTUS1,ABLIM1,EEF2,CACNB2,SMTN,LIMCH1,FMNL2,NOS3,EPB41L5,DPYSL5,MID2,CDH26,MYO10,SPATA6,HOMER2,PACSIN3,HIP1,OBSCN,PLS1,BAIAP2,BEX4,PLEKHH2,CLMN,CDH2,SHTN1,AMPD1,PRKN,EML5,SORBS1,DNM3,TMSB15A,PSTPIP2,MYO1B,COBLL1,ADD2,KIF21B,PPP1R9A,CTNNA2,SCIN,EPB41L3,ALDOC,REEP1,MYO3B,MYH15,MARCKS,RAB27B,JAKMIP3,HSPA2,GLI1,SSH3,GAPDH,EVL,TMEM67,TTLL7,SNCA,GABARAPL1,IFT81,GBP1,MID1,COBL,WASF3,MYO1D,FARP1,EPS8,KIF5C,FSD1,RAB11FIP5,MAP1A,GAS2L3,IQGAP3,MYO6,FES,MICAL2,SYNPO2,RAB3B,PXN,RAB6B,SYBU,PHACTR2,PALLD,SNTB1,MAP1B,MAP10,GCSAM,SVIL,MYOM2,KIF21A,KIF1B,TPT1 |
| 3.043e-08 | -17.31 | CERVERA_SDHB_TARGETS_2 | MSigDB lists | CERVERA_SDHB_TARGETS_2 | 103 | 30 | 17377 | 1707 |
MICAL2,UBASH3B,SYT12,WLS,MLF1,ESRP1,CTBP2,CREB5,OVOL2,ITPR2,TNFRSF19,LEPR,STEAP1,GALNT3,SIPA1L2,GPRC5B,THBS4,MATN2,TFAP2A,CADPS2,SERPINI1,GULP1,PCOLCE2,HS3ST3B1,FAM84B,SUSD4,MOXD1,TNFSF4,IL1RAP,DUSP1 |
| 3.064e-08 | -17.30 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | 71 | 24 | 17377 | 1707 |
RIN2,MXI1,RHOQ,PNRC1,CFH,RECK,ST6GAL1,EPS8,CYP4V2,SESN1,BBS9,GABARAPL1,ABLIM1,ALDOC,BNIP3,DBP,PROS1,GEM,NCAM1,MET,LIFR,SMPDL3A,CEBPD,IGFBP3 |
| 3.138e-08 | -17.28 | endomembrane system | cellular component | GO:0012505 | 4409 | 511 | 18223 | 1724 |
DOC2A,ATP8A1,DNAJC3,LDLR,VAMP8,MCOLN3,ALG1L,CHAC1,BCAN,PRKCA,SNX9,RAC3,SLC9A7,STK24,NCS1,NOS1AP,PCDH7,TXNDC5,ZFYVE28,SLC22A18,RAP2A,RAB26,KCNS3,NDUFB8,CHRDL1,TMED9,SP140,COG3,PACSIN1,CPE,TBC1D8,ERGIC1,WISP3,WLS,TGFA,LRRK2,LRMP,BNIP3L,HACD1,MSRB3,FEZ1,F12,ZDHHC14,GPC6,SH3RF1,NCKAP1L,RASGRF2,ATP7B,ALDOA,ADRB1,B3GALT2,BMP1,DSEL,SERPINI1,INPP5F,NRP1,SCN5A,INPPL1,ALOX5AP,TBC1D1,CYP2J2,ST6GAL1,DHCR24,APBA1,DYNC1I1,MYORG,MTUS1,MCOLN2,GBGT1,BNIP1,SLC7A11,MSMO1,BACE2,FLRT3,SREBF1,PRKG1,GRIP1,LMAN2,ST8SIA1,NCAM1,MOXD1,AGL,STXBP1,COL9A2,RPS23,LRP12,GPR161,HMGCR,FADS1,ENAM,BDNF,QSOX1,SLC37A1,PNP,TBC1D8B,SLC36A1,PLEKHA8,COL4A4,MGST3,VLDLR,FASN,PACSIN3,RYR2,HIP1,COLGALT2,CALCRL,ST6GALNAC3,AIG1,SHISA2,NPC2,SNAP25,RABAC1,ARRDC4,PLCB1,CLN5,VPS37D,SH3GL2,PKN3,PMEPA1,THBS4,QPCTL,SELENOM,SQLE,LAPTM4B,DHCR7,CDH2,DOCK9,PLA2G4A,EPHA3,FRMPD3,DNM3,PCSK1N,SCAMP1,ELOVL4,RHOD,RNF144A,GALNT12,GALNT6,C4A,MYO1B,RGS20,COLEC10,NRXN1,COL14A1,TBC1D30,ZFYVE9,TXNRD3,CDS1,CCDC120,GPR15,TLR3,ERG28,COL25A1,ALDOC,MAGEA3,SCRN1,NBEA,PDE4D,SERPINH1,JAKMIP3,RAB27B,SYNGR3,SNX10,PERP,B3GALT1,COL6A2,GAPDH,GARS,EBPL,TMEM43,CYB5R2,TRAM1L1,PANK1,CBY1,PXYLP1,RAB38,DSP,ASPH,TRIQK,TBC1D16,ATP10D,GABARAPL1,SNCA,GJC1,ARHGAP21,WFS1,PEMT,ASIC1,LAMB1,PAM,RCN3,P4HA1,ALG11,KLF5,HS3ST3B1,CTTNBP2,NR3C2,STON2,RAB30,HACE1,MYO1D,SERINC5,ANKRD13B,ANKRD13D,IGFBP6,GLIPR1L1,BACE1,ATP9A,FZD8,IPO5,BIK,UBAC2,ARL2,GAS6,PKN1,EPHB1,NDFIP2,SELENOP,GDPD5,SLC35G2,COL27A1,NEDD4,GSAP,NEO1,SOAT2,MGAT1,MCF2L,RMDN2,SGK3,PRKG2,MORN2,CERS4,DYNC2H1,FIG4,MYO6,TBC1D9,SMAD6,FES,B4GALT6,ULBP1,TRPM4,VEGFC,SLC40A1,GSTM2,RAB6B,AGPAT4,RAPGEF2,ELOVL3,RPL21,ZDHHC15,ATP11A,GALNT3,PTPRC,FGR,PLOD2,OSBPL5,XBP1,SRD5A3,BMP4,TNFRSF17,CERS1,B4GALT7,DDIT3,TPT1,ATP1A3,CCDC126,EXPH5,ACSL1,SYT12,NDRG2,ASS1,ITPR2,MGAT5B,NUP62CL,ABHD4,DNER,CHST10,CYP51A1,RTN1,RND2,ADPRHL1,FKBP9,TM9SF2,SEC16B,GRHL1,SLC10A7,ITGB3,COL19A1,JAKMIP2,SLC2A12,CTTN,MYRIP,GALNT18,TLR4,PDGFRB,RASGRP1,LAMP3,CYP1B1,ATL1,TNK2,CD55,KCNIP3,GCNT2,COL4A3,ABCC4,ANK2,JPH1,NFE2L1,COTL1,TRIM9,GSN,TMEM150B,HPSE,INSIG1,P4HA2,ERN1,TNFRSF1A,PIK3C2B,APBA2,MAGI2,CHMP4C,PCSK5,RRAGD,PRKAA2,UST,TYRO3,SV2B,FN1,LGALS3,HID1,SEC24D,ELOVL7,CYP4V2,ATP6V1E2,SCD,GALNT13,CHSY1,SPINK5,MLC1,PGAP1,RNF180,GALNT1,EEF2,SLC30A4,SEMA4F,ABCA5,BCHE,HS3ST5,LRP6,BNIP3,SLCO4C1,NCEH1,LRP3,CKAP4,SNX7,NOS3,PAK1,CHSY3,FGFR4,IL17RD,PODXL2,B3GLCT,SLC27A2,RNF170,PARD3B,MGAT4B,EDEM3,GPSM1,SDC3,GALNT17,B4GALNT3,STEAP1,HERPUD1,BAIAP2,TBC1D2,GLCE,PLAGL1,FCHO2,CSF1,MFSD2A,SH3BP4,RAB31,PTPRN2,TMEM117,PLD1,RNF122,OSBPL6,MME,CREB3L2,DMXL2,PRKN,ID1,IL15,LPCAT2,XYLT1,COL18A1,RNF24,FAM198B,CANX,LPIN3,SEZ6L2,DOCK2,CYP26A1,CD53,COL22A1,UNC13B,PDZD8,ERO1B,REEP1,ZDHHC6,BCL6,ZDHHC23,STEAP3,PROS1,CLVS2,TMEM120B,IGFBP3,ALG10B,GCA,ANTXR2,EVA1A,TMEM67,TUBA1A,LRRC8B,TDRD3,PTPN6,C3orf52,ACO1,RNF125,RARRES2,FRK,JAM3,SMAD3,RANBP2,PTPRJ,KPNA3,GBP1,PTPRS,HGF,CYP2U1,SEPT5,MBOAT2,RETREG1,ARFGEF3,TENM1,COL9A3,TNIK,PRSS16,TSPAN15,GRB14,CLGN,MCTP2,CLSTN2,SELL,COL4A5,RASD1,NOTUM,CUEDC2,ARHGAP44,RPL34,RAB11FIP5,FUT9,PRKCD,EHD3,STC2,KIAA0319,TFAP2A,SGK1,PRICKLE2,MARCH3,TRIM3,ESD,RRAS2,TESPA1,FKBP14,PCSK6,CES3,RAB3B,NR4A1,CYTH3,SYBU,LITAF,PRICKLE1,PHACTR2,ARHGAP32,FNDC3A,TLR6,GALNT14,LRAT,ILDR2,DKK1,DPY19L2,GPR37,ICA1,EDA,RND3,FBN1,ACER2,PRCP,FMO4,CTSV,SH3BGRL2,MYRF,RPL4,RPS12,TBC1D4,PTGES,MMP16,CACNA2D1,ABCG1,STOM |
| 3.205e-08 | -17.26 | brain | COSMIC cancer mutations | brain | 16658 | 1666 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 3.212e-08 | -17.25 | brain development | biological process | GO:0007420 | 690 | 111 | 17256 | 1658 |
ID1,FGF13,RBFOX2,OTX1,PLXNA2,NDRG2,ABAT,BCAN,RAC3,AARS,CBLN1,CTNNA2,SKI,BAG3,RIDA,EOMES,KCNAB1,TACC2,LHX6,DAB2IP,SYNGR3,ZNF365,SLIT2,POU3F3,GLI1,NKX2-1,FZD1,SMAD9,FZD4,WLS,SHANK2,LRRK2,ADCY1,NLGN4X,FEZ1,SATB2,EFHC1,AMIGO1,ATOH1,FGFR1,EML1,TSKU,IRS2,ARMC4,NRG3,GNB4,LAMB1,PTPRS,DLX2,OXTR,BMPR1A,NRP1,PPARGC1A,CTTNBP2,CNTN1,TYRO3,BCL11B,PCDH18,MYO1D,GNG12,SCN5A,BMPR2,ROBO2,OPHN1,ZIC2,PHGDH,SELENOP,GDPD5,FOXG1,CHD5,PGAP1,DDIT4,KDM7A,FOXP2,NUMBL,HMGCS1,CNTN4,SLC7A11,GATA2,AFF2,PRKG1,LRP6,BNIP3,DYNC2H1,ATP2B1,PAK1,RAX,UNC5C,MSX1,RAPGEF2,SLITRK5,MAFB,AK4,CLN5,PLCB1,BAIAP2,ZIC1,DKK1,RERE,DOCK7,FAT4,MFSD2A,GNAO1,AKT3,GRIN2D,BMP4,JHY,SEMA3A,CDH2,ATP2B4,SNPH |
| 3.275e-08 | -17.23 | GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION | MSigDB lists | GO_CELL_MORPHOGENESIS_INVOLVED_IN_NEURON_DIFFERENTIATION | 358 | 69 | 17377 | 1707 |
CELSR3,KIF5A,RBFOX2,PLXNA2,GATA3,ENAH,NRXN1,SEMA6A,CTNNA2,COL25A1,ETV1,SLIT2,NTNG1,SEMA6C,NKX2-1,ATL1,EVL,DCC,ADCY1,FEZ1,PRKCQ,ATOH1,AMIGO1,TSKU,MAP2,SEMA3C,UNC5B,NRP1,COBL,CTNND2,MEF2C,BCL11B,EFNB2,LRFN5,FARP1,ROBO2,LRP4,APBB1,OPHN1,KIF5C,SLC1A3,EPHB1,NEO1,CHN1,NUMBL,LRRC55,LRRN1,SEMA4F,CNTN4,SCN1B,PDZD7,FLRT3,NCAM1,STXBP1,DPYSL5,PAK1,BDNF,UNC5C,SLITRK2,VLDLR,EFNA3,SLITRK5,BAIAP2,RERE,MAP1B,DOCK7,MATN2,NKX2-8,SEMA3A |
| 3.316e-08 | -17.22 | lung-carcinoma-non_small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-non_small_cell_carcinoma | 5292 | 616 | 17385 | 1698 |
ARHGAP26,PDE1B,GRIK2,DNAJC3,NPM1,STAT5B,CEBPA,CADM2,SNX9,EYA4,NOS1AP,SKI,PCDH7,EPDR1,TXNDC5,BAG3,FBXO32,PMAIP1,PPFIA2,FAAH2,RAP2A,RAB26,PPP2R2B,NKX2-1,SMAD9,TGFA,LRRK2,MSRB3,FEZ1,PRKAR2B,INTS6,ATP7B,ALDOA,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,LPP,MEF2C,CARS,GNG12,LATS2,ITGA6,BTBD9,GPSM2,FOXG1,BBS9,CHN1,BNIP1,CACNB2,SRGAP1,TOX,ALPK1,LOXL4,MOXD1,ZNF518B,HMGCR,PNP,STAT4,ARID5B,EFHC2,RYR2,HIP1,CALCRL,SMARCD3,SNAP25,DHX32,BEX4,ADAMTS3,CLMN,HOXD13,SPRED3,FBXO27,TMSB15A,RGS20,IL13RA1,GRK6,COLEC10,TXNRD3,RNF150,DACT1,ALDH1L1,FAM133A,PJA1,FAM155B,ARL4D,RAB27B,SNX10,KCNB2,FZD1,SSH3,MYLK3,GARS,COL6A2,GAPDH,FZD4,NPM3,KCNH5,ADCY1,WNT11,RAB38,ASPH,FGFR1,GJC1,IRS2,CXCL10,ARHGAP21,GYPC,PEMT,LAMB1,INPP4B,TNFSF15,PLD5,RAB30,FARP1,WDR17,EDA2R,GCAT,FZD8,PLAG1,BIK,IPO5,UBAC2,GAS6,PKN1,EPHB1,KCNC4,TSPAN17,BEX2,PCBP4,MCF2L,GAS2L3,GHR,ZFP36L2,FES,BCL7A,RAB6B,MCF2L2,RAPGEF2,AK4,RASA3,SNTB1,PTPRC,TRIB3,ID3,NSD1,GNAO1,AKT3,XBP1,SLCO5A1,NEK11,PIP5KL1,BMP4,HK1,CRISPLD1,FOXA1,BTRC,TRIM2,FGF13,TRIM16,ITPR2,NUP62CL,NOVA1,PLS3,RND2,FKBP9,RPS6KA2,SEC16B,ITGB3,ENO1,TLR4,ETV1,NEB,RAPGEF5,PGBD5,ITGB7,MARK1,PNRC1,COL4A3,SPOCD1,CR2,PLEKHA1,BATF,SESN1,PLEKHB1,DYRK1B,TRIM9,KCNMB4,MAP2,GNB4,ERN1,TNFRSF1A,PIK3C2B,MLLT3,RRAGD,PRKAA2,KCNV1,RGS16,RUNX2,STXBP5L,ZCCHC24,SETBP1,ZNF215,DOK5,FHOD3,HSPA12B,NUMBL,IGF1R,GATA2,FRAS1,LRP6,BNIP3,PTPRCAP,FBXL2,PAK1,FGFR4,MID2,RNF170,EFNA3,SPATA13,PPFIA4,STRADB,OBSCN,MAFB,SLITRK5,KHDRBS2,MAPKAPK2,GRIK4,PLD1,SEMA3A,RNF122,SFN,ID1,CFH,AKAP5,DOCK1,XYLT1,RNF24,NTRK3,SLC7A2,KIF21B,RADIL,PPP1R9A,PCLO,TBC1D19,SLC22A17,TACC2,MYO3B,BCL6,GLI1,CSN2,TDRD3,ACO1,RNF125,CHRNA6,VIM,FBXO36,PAGE5,FRK,SMAD3,RANBP2,PTPRJ,ANKRD31,PTK7,ITGA2,PTPRS,MAOA,SEPT5,CTNND2,CNTN1,HEY1,COL9A3,DYRK3,BMPR2,KLHL13,GRB14,MCTP2,NLRP14,RASD1,USP30,PPP2R3A,FOXP2,RASD2,SGK1,PCK2,SYK,SLC45A3,KIAA1211,DUSP1,DLGAP1,PPP1R3D,FOXN3,CRIP2,LITAF,NUAK2,ILDR2,MGMT,DKK1,FAT4,FMO4,ZNF808,SH3BGRL2,PAX9,PTGES,KIF1B,CACNA2D1,MYCBP2,ACVR1,PAGE1,LANCL3,LGR4,DUSP8,LDLR,PPFIBP2,GATA3,ENAH,ADAMTS6,PRKCA,DACH2,RAC3,HECTD2,STK24,SLC9A7,TRPS1,SLC16A2,CHRDL1,VWA5A,RCAN3,PLTP,ACVR1C,KLHL4,FAM84A,LRMP,DNAJC6,BNIP3L,DEPTOR,TNS1,ACVR2B,ZDHHC14,SAV1,GNAI1,AHRR,HLF,PLK2,RASGRF2,CCBE1,SERPINI1,MAPK13,SPRY4,UNC5B,KLF8,INPPL1,ALOX5AP,PTPRD,ST6GAL1,MLF1,OPHN1,MRPL22,GTF2IRD1,TNFRSF10C,WDFY4,SLC1A3,TNFRSF19,CHD5,GAS1,MECOM,ABLIM1,NAV1,RALGPS2,ADCK1,NOVA2,PDZD7,MYC,PRKG1,SLC16A9,MPDZ,SAMD13,RIMS2,RNF152,IGSF3,PTCH2,RPL26,TBC1D8B,PLEKHA8,RAPGEF4,TTC30A,PEX5L,CDC42BPA,PLCB1,FAM162A,TMEM74,MMP15,DAGLA,PLEKHH2,PKN3,PMEPA1,CECR2,IQSEC2,DHCR7,SMYD3,AMPD1,FRMPD3,EPHA3,PLA2G4A,PCSK1N,RHOD,RNF144A,CHUK,COL14A1,DDR1,ZFYVE9,CCDC120,SPEG,NELL2,ASNS,ZNF438,ALDOC,STARD4,NAP1L3,PDE4D,SERPINH1,GAB2,TRDMT1,PDK1,PREX1,NLGN4X,ATF3,PRKCQ,PNMA6A,SATB2,PYGO1,ZNF711,HTR7,IKZF3,PRKCB,CCNA1,GRB10,BMPR1A,MID1,COBL,HACE1,MXI1,HERC5,ARL2,RGS7,INPP1,NEDD4,RGS17,IRX5,MGAT1,GPR155,AFF2,SGK3,RALGAPA2,SMAD6,SPRY2,TMC7,VAV3,PXN,ALDH2,MPP1,PTPN13,ZDHHC15,GPLD1,CEBPB,FGR,TERT,TNFRSF17,DDIT3,ACSL1,PTPN21,SLC2A13,IKZF2,KREMEN1,FKBP11,ARHGEF10L,RTN1,SIPA1L2,PPM1E,AKAP7,POF1B,HRK,CTTN,PTPRE,SLIT2,PRKACB,PDGFRB,RASGRP1,TNK2,SESN2,YAP1,ROR1,TMEM47,COTL1,SGK2,RNF44,SERGEF,AK1,HPSE,ITGBL1,FAM114A2,NCOA7,PPARGC1A,TNFSF4,BCL11B,RHOBTB1,FBXO4,JDP2,CYP4V2,LAMC3,SPINK5,SATB1,DDIT4,PCDHB14,RNF141,EEF2,RNF148,SNX7,RHOQ,SLITRK2,MSTN,SDC3,DUSP9,PRDM1,KIAA0355,CSAG1,FAT1,HK2,RAI14,RAB31,PTPRN2,FNBP1L,NKX2-8,CXCR5,NEK10,PSTPIP2,PLEKHA5,ARHGAP22,HECW2,MORC4,COBLL1,BCL6B,COL22A1,CDC14B,RPS6KL1,KAZN,PPFIBP1,ZNF521,ACVR2A,MDH1B,POU2F2,MET,HSPA2,SUSD3,FER,PTPRU,PTPN6,CD40,DOCK5,BCL11A,WARS,ARMC4,MAGEA12,BACH2,TRIM34,KPNA3,EIF4EBP1,RGS10,DUSP19,RNF130,LIFR,MAST1,TNIK,ENO2,ARHGEF11,CLGN,REL,TNFSF13B,CLSTN2,IGF2BP2,COL4A5,MCU,RAB11FIP5,CHN2,PRKCD,TRIM3,RRAS2,FKBP14,TNFRSF11A,CARD6,RIN2,MSX1,USP2,RAB3B,CRIM1,CYTH3,SYBU,OGDHL,PRRG1,MARS,AGAP2,CCNG1,ARHGAP32,TLR6,ADAMTS17,SUGT1,EDA,RND3,MAP2K6,KIAA0513,GEM,RNF157,IL9R,MMP16,SNPH |
| 3.316e-08 | -17.22 | non_small_cell_carcinoma | COSMIC cancer mutations | non_small_cell_carcinoma | 5292 | 616 | 17385 | 1698 |
ARHGAP26,PDE1B,GRIK2,DNAJC3,NPM1,STAT5B,CEBPA,CADM2,SNX9,EYA4,NOS1AP,SKI,PCDH7,EPDR1,TXNDC5,BAG3,FBXO32,PMAIP1,PPFIA2,FAAH2,RAP2A,RAB26,PPP2R2B,NKX2-1,SMAD9,TGFA,LRRK2,MSRB3,FEZ1,PRKAR2B,INTS6,ATP7B,ALDOA,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,LPP,MEF2C,CARS,GNG12,LATS2,ITGA6,BTBD9,GPSM2,FOXG1,BBS9,CHN1,BNIP1,CACNB2,SRGAP1,TOX,ALPK1,LOXL4,MOXD1,ZNF518B,HMGCR,PNP,STAT4,ARID5B,EFHC2,RYR2,HIP1,CALCRL,SMARCD3,SNAP25,DHX32,BEX4,ADAMTS3,CLMN,HOXD13,SPRED3,FBXO27,TMSB15A,RGS20,IL13RA1,GRK6,COLEC10,TXNRD3,RNF150,DACT1,ALDH1L1,FAM133A,PJA1,FAM155B,ARL4D,RAB27B,SNX10,KCNB2,FZD1,SSH3,MYLK3,GARS,COL6A2,GAPDH,FZD4,NPM3,KCNH5,ADCY1,WNT11,RAB38,ASPH,FGFR1,GJC1,IRS2,CXCL10,ARHGAP21,GYPC,PEMT,LAMB1,INPP4B,TNFSF15,PLD5,RAB30,FARP1,WDR17,EDA2R,GCAT,FZD8,PLAG1,BIK,IPO5,UBAC2,GAS6,PKN1,EPHB1,KCNC4,TSPAN17,BEX2,PCBP4,MCF2L,GAS2L3,GHR,ZFP36L2,FES,BCL7A,RAB6B,MCF2L2,RAPGEF2,AK4,RASA3,SNTB1,PTPRC,TRIB3,ID3,NSD1,GNAO1,AKT3,XBP1,SLCO5A1,NEK11,PIP5KL1,BMP4,HK1,CRISPLD1,FOXA1,BTRC,TRIM2,FGF13,TRIM16,ITPR2,NUP62CL,NOVA1,PLS3,RND2,FKBP9,RPS6KA2,SEC16B,ITGB3,ENO1,TLR4,ETV1,NEB,RAPGEF5,PGBD5,ITGB7,MARK1,PNRC1,COL4A3,SPOCD1,CR2,PLEKHA1,BATF,SESN1,PLEKHB1,DYRK1B,TRIM9,KCNMB4,MAP2,GNB4,ERN1,TNFRSF1A,PIK3C2B,MLLT3,RRAGD,PRKAA2,KCNV1,RGS16,RUNX2,STXBP5L,ZCCHC24,SETBP1,ZNF215,DOK5,FHOD3,HSPA12B,NUMBL,IGF1R,GATA2,FRAS1,LRP6,BNIP3,PTPRCAP,FBXL2,PAK1,FGFR4,MID2,RNF170,EFNA3,SPATA13,PPFIA4,STRADB,OBSCN,MAFB,SLITRK5,KHDRBS2,MAPKAPK2,GRIK4,PLD1,SEMA3A,RNF122,SFN,ID1,CFH,AKAP5,DOCK1,XYLT1,RNF24,NTRK3,SLC7A2,KIF21B,RADIL,PPP1R9A,PCLO,TBC1D19,SLC22A17,TACC2,MYO3B,BCL6,GLI1,CSN2,TDRD3,ACO1,RNF125,CHRNA6,VIM,FBXO36,PAGE5,FRK,SMAD3,RANBP2,PTPRJ,ANKRD31,PTK7,ITGA2,PTPRS,MAOA,SEPT5,CTNND2,CNTN1,HEY1,COL9A3,DYRK3,BMPR2,KLHL13,GRB14,MCTP2,NLRP14,RASD1,USP30,PPP2R3A,FOXP2,RASD2,SGK1,PCK2,SYK,SLC45A3,KIAA1211,DUSP1,DLGAP1,PPP1R3D,FOXN3,CRIP2,LITAF,NUAK2,ILDR2,MGMT,DKK1,FAT4,FMO4,ZNF808,SH3BGRL2,PAX9,PTGES,KIF1B,CACNA2D1,MYCBP2,ACVR1,PAGE1,LANCL3,LGR4,DUSP8,LDLR,PPFIBP2,GATA3,ENAH,ADAMTS6,PRKCA,DACH2,RAC3,HECTD2,STK24,SLC9A7,TRPS1,SLC16A2,CHRDL1,VWA5A,RCAN3,PLTP,ACVR1C,KLHL4,FAM84A,LRMP,DNAJC6,BNIP3L,DEPTOR,TNS1,ACVR2B,ZDHHC14,SAV1,GNAI1,AHRR,HLF,PLK2,RASGRF2,CCBE1,SERPINI1,MAPK13,SPRY4,UNC5B,KLF8,INPPL1,ALOX5AP,PTPRD,ST6GAL1,MLF1,OPHN1,MRPL22,GTF2IRD1,TNFRSF10C,WDFY4,SLC1A3,TNFRSF19,CHD5,GAS1,MECOM,ABLIM1,NAV1,RALGPS2,ADCK1,NOVA2,PDZD7,MYC,PRKG1,SLC16A9,MPDZ,SAMD13,RIMS2,RNF152,IGSF3,PTCH2,RPL26,TBC1D8B,PLEKHA8,RAPGEF4,TTC30A,PEX5L,CDC42BPA,PLCB1,FAM162A,TMEM74,MMP15,DAGLA,PLEKHH2,PKN3,PMEPA1,CECR2,IQSEC2,DHCR7,SMYD3,AMPD1,FRMPD3,EPHA3,PLA2G4A,PCSK1N,RHOD,RNF144A,CHUK,COL14A1,DDR1,ZFYVE9,CCDC120,SPEG,NELL2,ASNS,ZNF438,ALDOC,STARD4,NAP1L3,PDE4D,SERPINH1,GAB2,TRDMT1,PDK1,PREX1,NLGN4X,ATF3,PRKCQ,PNMA6A,SATB2,PYGO1,ZNF711,HTR7,IKZF3,PRKCB,CCNA1,GRB10,BMPR1A,MID1,COBL,HACE1,MXI1,HERC5,ARL2,RGS7,INPP1,NEDD4,RGS17,IRX5,MGAT1,GPR155,AFF2,SGK3,RALGAPA2,SMAD6,SPRY2,TMC7,VAV3,PXN,ALDH2,MPP1,PTPN13,ZDHHC15,GPLD1,CEBPB,FGR,TERT,TNFRSF17,DDIT3,ACSL1,PTPN21,SLC2A13,IKZF2,KREMEN1,FKBP11,ARHGEF10L,RTN1,SIPA1L2,PPM1E,AKAP7,POF1B,HRK,CTTN,PTPRE,SLIT2,PRKACB,PDGFRB,RASGRP1,TNK2,SESN2,YAP1,ROR1,TMEM47,COTL1,SGK2,RNF44,SERGEF,AK1,HPSE,ITGBL1,FAM114A2,NCOA7,PPARGC1A,TNFSF4,BCL11B,RHOBTB1,FBXO4,JDP2,CYP4V2,LAMC3,SPINK5,SATB1,DDIT4,PCDHB14,RNF141,EEF2,RNF148,SNX7,RHOQ,SLITRK2,MSTN,SDC3,DUSP9,PRDM1,KIAA0355,CSAG1,FAT1,HK2,RAI14,RAB31,PTPRN2,FNBP1L,NKX2-8,CXCR5,NEK10,PSTPIP2,PLEKHA5,ARHGAP22,HECW2,MORC4,COBLL1,BCL6B,COL22A1,CDC14B,RPS6KL1,KAZN,PPFIBP1,ZNF521,ACVR2A,MDH1B,POU2F2,MET,HSPA2,SUSD3,FER,PTPRU,PTPN6,CD40,DOCK5,BCL11A,WARS,ARMC4,MAGEA12,BACH2,TRIM34,KPNA3,EIF4EBP1,RGS10,DUSP19,RNF130,LIFR,MAST1,TNIK,ENO2,ARHGEF11,CLGN,REL,TNFSF13B,CLSTN2,IGF2BP2,COL4A5,MCU,RAB11FIP5,CHN2,PRKCD,TRIM3,RRAS2,FKBP14,TNFRSF11A,CARD6,RIN2,MSX1,USP2,RAB3B,CRIM1,CYTH3,SYBU,OGDHL,PRRG1,MARS,AGAP2,CCNG1,ARHGAP32,TLR6,ADAMTS17,SUGT1,EDA,RND3,MAP2K6,KIAA0513,GEM,RNF157,IL9R,MMP16,SNPH |
| 3.324e-08 | -17.22 | thyroid-carcinoma | COSMIC cancer mutations | thyroid-carcinoma | 4219 | 505 | 17385 | 1698 |
ARHGAP26,MYCBP2,CGN,LGR4,FLVCR2,TCP11L2,SIDT1,GRIK2,CNTNAP3,PRSS12,RECK,NPM1,STAT5B,DOCK3,KIAA1217,SNX9,ABHD6,EYA4,TRPS1,TYMP,TGFBR3,ZFYVE28,DNAH6,GSTM3,TMEM37,MAGEA6,THSD1,CPE,PLTP,TSHR,NKX2-1,SMAD9,DCC,WLS,FAM84A,KLHL4,LRRK2,NFIA,MEF2B,FEZ1,ABCC2,TNS1,ACVR2B,ZDHHC14,CA13,GPC6,ENPP1,ENPP6,NCKAP1L,PLK2,ATP7B,RASGRF2,BMP1,INPP5F,CAB39L,NRP1,UNC5B,DNHD1,SPOCK3,MEF2C,CARS,SEMA6B,SCN5A,LATS2,STOX2,INPPL1,PTPRD,ZHX3,TBC1D1,ITGA6,DHCR24,GTF2IRD1,TJP1,LRRC49,APBA1,DYNC1I1,ADSSL1,TTC30B,GAS1,MCOLN2,CHN1,IL17D,NAV1,BNIP1,SLC7A11,RALGPS2,FRY,KIAA1257,ADCK1,PIK3AP1,MYC,PRKG1,SREBF1,MPDZ,ALPK1,ST8SIA1,FAM155A,AGL,STXBP1,COL9A2,RIMS2,CHRM3,FADS1,TBC1D8B,MYO10,COL4A4,STAT4,VLDLR,ARID5B,DCHS1,FASN,PACSIN3,RYR2,SMARCD3,C1R,ZBBX,PLCB1,DHX32,DAGLA,CACHD1,TEX15,PLEKHH2,ADAMTS3,THBS4,LRRIQ3,INHBE,SQLE,IQSEC2,AMPD1,FRMPD3,AMOTL1,RASAL2,TMSB15A,GALNT12,C4A,FAM131C,ZNF311,MYO1B,LRRCC1,PLXNA2,OTX1,ADD2,CHUK,COLEC10,NRXN1,NUDT12,COL14A1,ZFYVE9,TIAM2,TMEM53,EPB41L3,TLR3,COL25A1,MAGEA3,ALDH1L1,FAM133A,NAP1L3,PDE4D,SERPINH1,JAKMIP3,DNAH5,DOCK8,SCN3A,FZD1,C3orf67,VNN2,SSH3,MYLK3,COL6A2,EBPL,CYB5R2,NPM3,SHANK2,ADCY1,PREX1,WNT11,PYGO1,DSP,TBC1D16,ZNF618,C9orf116,FGFR1,MAGI3,SLC39A14,IRS2,PDLIM3,TDO2,WFS1,LAMB1,PLEKHG1,GRB10,PLD5,CTTNBP2,NR3C2,COBL,STON2,HACE1,CGB2,DENND5B,MYO1D,FARP1,ANKRD13D,WDR17,ROBO2,FZD8,ESRP1,PLAG1,PSD3,SLC12A6,GABRR2,EPHB1,NDFIP2,KCNC4,COL27A1,NEDD4,NEO1,LRRC55,LRRN1,AFF2,GPR155,GAS2L3,GHR,RALGAPA2,DYNC2H1,MYO6,ERRFI1,GFI1,ZFP36L2,MED12L,PARP9,ULBP1,PDLIM7,TRPM4,TMC7,PFKFB4,SLC40A1,VAV3,SYNPO2,ARAP2,LCA5,CACNA1E,MCF2L2,PTPN13,ATP11A,HOXA1,ZIC1,GPLD1,HEG1,TRIB3,NSD1,FGR,RPL12,OR2T33,PCDHB7,TERT,PLXDC2,GNAO1,MCC,SVIL,GRIN2D,MYOM2,DOCK6,ATP2B4,OCLN,BTRC,TLL2,TPT1,NUDT17,ATP1A3,EXPH5,SYT12,PTPN21,LILRB1,MGAT5B,ABAT,ITPR2,FAM13A,ABHD4,RBM11,SLCO3A1,HMCN1,CHST10,QPRT,CCNJ,ANKRD42,ARHGEF10L,EPCAM,SIPA1L2,KCNAB1,HPS1,ABI3BP,ITGB3,TMEM143,COL19A1,JAKMIP2,TLN2,MYRIP,TLR4,ETV1,NEB,SLIT2,RASGRP1,PDGFRB,LAMP3,DBN1,ATL1,ITGB7,KCNIP3,SKAP2,COL4A3,ANK2,GDPD1,ZNF565,CR2,TMEM47,BATF,TCERG1L,SESN1,SPNS1,DYRK1B,TMEM132B,TCF7L1,INHBC,GPRC5B,ITGBL1,NCAM2,MAP2,TECPR2,TIGD4,TNFSF4,MAGI2,FRMD5,RRAGD,LONRF1,STXBP5L,FN1,SEC24D,UBASH3B,SETBP1,LAMC3,SORBS3,ZIC2,SPINK5,PHGDH,DOK5,FHOD3,PCDHB14,GALNT1,KIAA1958,IGF1R,ABCA5,FRAS1,HS3ST5,SLCO4C1,RNF148,FBXL2,CKAP4,SNX7,DPYSL5,CHSY3,CDH26,MID2,ANKRD20A2,PODXL2,RNF170,SH2D2A,TCEA3,TMTC4,EDEM3,PPFIA4,SDC3,WWC1,OBSCN,SDK1,B4GALNT3,KHDRBS2,AMDHD1,TBC1D2,GLCE,HEYL,FAT1,RAI14,HK2,PTPRN2,SEMA3A,FNBP1L,DMXL2,NEK10,CFH,PLEKHA5,RHPN2,NTRK3,ZNF83,LPIN3,CANX,FAM110B,TNKS1BP1,PIBF1,DOCK2,SEMA6A,DDX60L,PCLO,ZSCAN5A,ZNF362,COL22A1,UNC13B,TACC2,KAZN,ZNF521,BCL6,ACVR2A,MYH15,GULP1,PROS1,MET,SCN2A,POU2F2,HSPA2,NTNG1,SNAI2,SP140L,ALG10B,INTU,ANTXR2,PHLDB2,TMEM67,PTPRU,LRRC8B,PRDM13,TCEAL3,AMIGO1,TTLL7,DOCK5,WARS,BCL11A,RANBP2,PTPRJ,LMLN,TRIM34,ITGA2,PTPRS,DISP1,CYP2U1,SUSD4,MBOAT2,LIFR,CTNND2,PSPH,MAST1,TENM1,TNIK,KLHL13,TSPAN15,APBB1,LRP4,MCTP2,SSX1,NSUN6,CLSTN2,COL4A5,PRDM8,FAM117B,SEL1L3,BMP6,MAP1A,SCN1B,FUT9,RASD2,STC2,TSC22D1,GTF2F2,PRICKLE2,SGK1,AFAP1L2,PCK2,KIAA1211,CARD6,USP2,OGDHL,GRID1,PRRG1,PRICKLE1,MARS,TGDS,FNDC3A,ZFPM2,GALNT14,NAALADL2,MGMT,MAP1B,RERE,EBF1,DOCK7,EDA,FBN1,MAP2K6,THSD7B,KIAA0513,RPL4,SLC1A5,TBC1D4,PTGES,KIF1B,MMP16,FILIP1 |
| 3.437e-08 | -17.19 | GO_CELL_LEADING_EDGE | MSigDB lists | GO_CELL_LEADING_EDGE | 337 | 66 | 17377 | 1707 |
AMOTL1,AKAP5,ENAH,SNX9,RAC3,PPP1R9A,CTNNA2,TIAM2,EPB41L3,ITGB3,CTTN,PACSIN1,TLN2,DOCK8,FER,PHLDB2,EVL,ATF4,WLS,VIM,PLEKHA1,ARHGEF26,GABARAPL1,SLC39A14,GSN,PTPRJ,SH3RF1,ABI3,SPRY4,TPM1,COBL,MYO1D,WASF3,INPPL1,ROBO2,SLK,EPS8,APBB1,GABRG2,ARHGAP44,ABLIM1,ACTA2,MYO6,SPRY2,ATP2B1,PDLIM7,PAK1,EPB41L5,PXN,MYO10,PTPN13,CYTH3,ASAP3,SPATA13,FERMT2,WWC1,CDC42BPA,PALLD,BAIAP2,PLEKHH2,FGR,MYADM,FAT1,MCC,CDH2,TESC |
| 3.513e-08 | -17.16 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | 188 | 44 | 17377 | 1707 |
DMXL2,NMNAT3,ELOVL4,TTC39B,ZNF395,IL15,SEC24D,CKAP2,CCDC110,GTF2IRD1,RGS7,KIAA1217,TNKS1BP1,PIBF1,FHOD3,KIAA1958,TGFBR3,CDC14B,EEPD1,MYO6,VWA5A,ZNF365,MAST4,C15orf41,DUSP1,EPB41L5,GCA,SLC37A1,KLHL23,ATF7IP2,LITAF,PLS1,BATF,CD40,SPATA7,GLCE,EMILIN2,RGS10,ZNF704,SH3BGRL2,BMPR1A,SUSD4,COBL,DCBLD1 |
| 3.655e-08 | -17.12 | ZHAN_MULTIPLE_MYELOMA_CD1_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_UP | 43 | 18 | 17377 | 1707 |
MTG1,GPT2,GPR63,SESN2,KLHL4,PHGDH,TBC1D16,BATF3,CEBPB,TRIB3,SLC7A11,EIF4EBP1,STC2,ADRB1,RAB31,INHBE,PCK2,CTH |
| 3.961e-08 | -17.04 | WU_CELL_MIGRATION | MSigDB lists | WU_CELL_MIGRATION | 176 | 42 | 17377 | 1707 |
EFNB2,LGALS3,FN1,IGFBP6,ST14,ESRP1,EPS8,RGS20,GATA3,COL18A1,IGF2BP2,FKBP11,MTUS1,EPCAM,EFEMP1,GALNT1,MAGEA3,GSTM3,TSPAN13,LIMCH1,MAGEA6,PERP,SNAI2,IGFBP3,CD55,COL6A2,SLC27A2,ARID5B,VIM,GALNT14,MAP1B,DCBLD2,GALNT3,PLAGL1,WWTR1,RAB31,AHNAK2,MAOA,KLF5,MAPK13,PTGES,SFN |
| 4.204e-08 | -16.98 | GO_REGULATION_OF_NEURON_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_NEURON_DIFFERENTIATION | 531 | 92 | 17377 | 1707 |
EPHA3,NBL1,DNM3,ID1,FGF13,AKAP5,PLXNA2,GATA3,NTRK3,RAC3,SEMA6A,PPP1R9A,NCS1,STK24,RND2,EOMES,RAP2A,BCL6,DAB2IP,MARCKS,CTTN,PACSIN1,SLIT2,SEMA6C,DBN1,SSH3,DCC,LRRK2,PREX1,FEZ1,VIM,AMIGO1,ATOH1,FGFR1,BCL11A,GPRC5B,PTK7,PLK2,SEMA3C,HGF,INPP5F,NRP1,MAGI2,COBL,LZTS1,MEF2C,CNTN1,UST,BCL11B,TNIK,SEMA6B,BMPR2,ROBO2,FN1,PTPRD,LRP4,APBB1,GDPD5,BMP6,NEDD4,NKX6-1,EFEMP1,CHN1,NUMBL,CNTN4,SEMA4F,SCN1B,GATA2,KIAA0319,ADCY6,SGK1,FIG4,GFI1,RIMS2,FES,BDNF,DISC1,RAPGEF2,VLDLR,SNAP25,SDK1,CPEB1,BAIAP2,MAP1B,DKK1,NEGR1,HEYL,BMP4,SHOX2,SEMA3A,CDH2,FOXA1 |
| 4.234e-08 | -16.98 | acute_lymphoblastic_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_leukaemia | 2248 | 293 | 17385 | 1698 |
MYCBP2,ACVR1,LGR4,GRIK2,LDLR,NPM1,STAT5B,CTBP2,CEBPA,BCAN,PRKCA,KIAA1217,EYA4,STK24,TRPS1,BAG3,PPFIA2,PACSIN1,ACVR1C,KLHL4,LRRK2,NFIA,EFHC1,ABCC2,TNS1,ACVR2B,SAV1,PLK2,ATP7B,BMP1,MAPK13,CRYL1,MEF2C,LATS2,INPPL1,FAM124A,APBA1,DYNC1I1,FRY,KIAA1671,ADCK1,PIK3AP1,APLF,CACNB2,ZIC5,PRKG1,GRIP1,TOX,TSPAN12,ALPK1,FAM84B,GPR161,HMGCR,EPB41L5,RAPGEF4,FASN,ZBBX,CDC42BPA,MMP15,CACHD1,PLEKHH2,PKN3,THBS4,DYNC2LI1,DOCK9,EPHA3,ST14,GALNT12,PKP2,CHUK,GRK6,DDR1,TIAM2,SPEG,ASNS,COL25A1,DAB2IP,DNAH5,VNN2,MYLK3,COL6A2,PDK1,PFKFB2,PRKCQ,TBC1D16,FGFR1,IKZF3,POPDC3,PRKCB,LAMB1,BMPR1A,NR3C2,COBL,DENND5B,ANKRD13D,GLIPR1L1,PRSS35,PKN1,EPHB1,TSPAN17,COL27A1,HMGCS1,SOAT2,LRRN1,SGK3,ZFP36L2,FES,TMC7,PFKFB4,PTPN13,GUCY1A2,ZIC1,GPLD1,PTPRC,TRIB3,FGR,AKT3,PGM2L1,NEK11,HK1,DOCK6,OCLN,TLL2,ATP1A3,MPZL3,KIF5A,PTPN21,FHDC1,TNFAIP8L2,MGAT5B,IKZF2,HMCN1,FSTL5,CCNJ,LGI2,FKBP9,RPS6KA2,AADAT,KCNN2,ANKFN1,LIN7A,COL19A1,TLN2,ENO1,TLR4,OR2W3,IL1RAP,PDGFRB,PRKACB,DBN1,ITGB7,TNK2,ATL1,CD55,MARK1,SLC3A2,COL4A3,ABCC4,SPOCD1,ANK2,ZNF565,CR2,ROR1,SGK2,RNF44,SESN1,TRIM9,DYRK1B,SPNS1,KCNMB4,HPSE,MAP2,P4HA2,ERN1,NCOA7,MAGI2,TC2N,PRKAA2,STXBP5L,ZNF395,RIMKLA,ATP6V1E2,SETBP1,SPINK5,DOK5,FHOD3,HSPA12B,KIAA1958,GALNT1,RNF180,IGF1R,GATA2,PDE10A,FRAS1,FBXL2,LRP3,SNX7,PAK1,FGFR4,SLITRK2,PARD3B,PPFIA4,OBSCN,STRADB,WWC1,SDC3,B4GALNT3,LDHD,MAPKAPK2,KIAA0355,FAT1,RAI14,TMEM117,DISP2,NKX2-8,PANK3,SFN,NEK10,CELSR3,DOCK1,IL15,PLEKHA5,COBLL1,COL18A1,HECW2,RNF24,TDRKH,NTRK3,FAM198B,KIF21B,LPIN3,PCLO,TACC2,CDC14B,RPS6KL1,PPFIBP1,MYO3B,ACVR2A,MYH15,FHIT,MET,HSPA2,GLI1,CTH,FER,EVL,TMEM65,MVD,CHRNA6,AMIGO1,FRK,BCL11A,CAMK2N1,TMPRSS9,PTK7,SUSD4,MAST1,TENM1,TNIK,DYRK3,BMPR2,ENO2,PRSS16,COL4A5,NOTUM,MCU,KCNJ4,MAP1A,PRKCD,DSG2,TSC22D1,TFAP2A,ACTA2,SGK1,SH3PXD2B,SYK,PPP1R3D,USP2,HNF4G,NUAK2,OGDHL,ARHGAP32,MKX,EBF1,ICA1,FAT4,L3MBTL4,MAP2K6,UACA,DLG2,KIF21A,SLC1A5,KIF1B |
| 4.418e-08 | -16.93 | liver | COSMIC cancer mutations | liver | 16606 | 1662 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,QPCTL,CLMN,LAPTM4B,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,LINC00896,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 4.449e-08 | -16.93 | head_neck | COSMIC cancer mutations | head_neck | 15829 | 1603 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,ANKRD18B,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,ITGB3,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,ATRNL1,BEND4,MAGEA6,VWA5A,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,LINC00896,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,THOC3,DENND5B,WASF3,ANO10,ANKRD13D,MXI1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,EBF4,FAM107B,MORN4,NOS3,GPR176,ANKRD20A2,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,HSPA2,SUSD3,DPP10,PHLDB2,FER,SLC39A8,TES,TTLL7,DOCK5,C1orf174,TPK1,WARS,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,MYADM,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 4.632e-08 | -16.89 | animal organ morphogenesis | biological process | GO:0009887 | 875 | 133 | 17256 | 1658 |
ACVR1,LGR4,GATA3,SKI,TGFBR3,DLX6,CPE,PDGFRB,NKX2-1,KLHL3,LRRK2,YAP1,ACVR2B,PLEKHA1,SAV1,TSKU,INSIG1,BMP1,SEMA3C,DLX2,NRP1,TPM1,MEF2C,BCL11B,SCN5A,INPPL1,RUNX2,CELSR1,ITGA6,CHSY1,FOXG1,ADGRG6,EFEMP1,SYCP2,ABLIM1,CA2,PDZD7,GATA2,FRAS1,MYC,LRP6,TSPAN12,ENAM,DCHS1,ARID5B,FHL2,SMARCD3,RYR2,NSD2,MAFB,PRDM1,SDK1,HEYL,CSF1,WDR19,HOXD13,CDH2,SEMA3A,SIX2,ID1,OTX1,COL18A1,PKP2,DDR1,SEMA6A,CTNNA2,SETDB2,MYO3B,SERPINH1,SNAI2,PERP,FZD1,GLI1,EVL,NKX3-2,SHANK2,WNT11,SATB2,ATOH1,DSP,FGFR1,SMAD3,NRG3,RBPMS2,PTK7,WWTR1,ITGA2,LAMB1,PAM,BMPR1A,HEY1,BMPR2,PLAG1,LRP4,OVOL2,EPHB1,PHLDA2,BMP6,COL27A1,NKX6-1,IRX5,TFAP2A,ACTA2,SH3PXD2B,ERRFI1,SMAD6,SYK,SPRY2,VEGFC,SLC40A1,MICAL2,MSX1,KDM5B,FOXN3,ZFPM2,HOXA1,HEG1,ZIC1,CEBPB,ID3,EDA,FAT4,FBN1,AKT3,PCGF2,TUFT1,MYOM2,BMP4,PAX9,SHOX2,MMP16,BTRC,FOXA1 |
| 4.757e-08 | -16.86 | PH | pfam domains | PF00169 | 178 | 42 | 17054 | 1666 |
ARHGAP26,FARP1,DNM3,GRB14,PLEKHA5,ARHGAP22,OPHN1,TIAM2,RALGPS2,MCF2L,AFAP1L2,CADPS2,RTKN2,IPCEF1,GAB2,VAV3,PHLDB2,SH3BP2,ARAP2,SKAP2,MYO10,PLEKHA8,CYTH3,ASAP3,SPATA13,FERMT2,RASA3,PLEKHA1,SNTB1,SKAP1,GRK3,PLEKHB1,TBC1D2,IRS2,PLEKHH2,RASGRF2,AKT3,OSBPL5,GRB10,PLD1,KIF1B,DOCK9 |
| 5.228e-08 | -16.77 | GO_REGULATION_OF_TRANSPORT | MSigDB lists | GO_REGULATION_OF_TRANSPORT | 1733 | 236 | 17377 | 1707 |
EXPH5,DOC2A,CACNG3,LGR4,TRIM16,SYT12,ATP8A1,VAMP8,GATA3,LILRB1,ITPR2,ABAT,SYT14,PRKCA,CACNB4,NCS1,NOS1AP,ADPRHL1,KCNN2,SEC16B,KCNAB1,PMAIP1,AKAP7,ITGB3,RAB26,KCNS3,TRPC1,TMEM37,PACSIN1,PLTP,TLR4,MYRIP,RASGRP1,PDGFRB,TBC1D8,TNK2,KCNIP3,ATF4,ACVR1C,WLS,ANK2,LRRK2,DNAJC6,JPH1,ELMOD1,BNIP3L,KCND3,SGK2,SERGEF,TRIM9,ENPP1,KCNMB4,INSIG1,NCKAP1L,BBC3,INPP5F,OXTR,NRP1,TNFSF4,PPARGC1A,MAGI2,TC2N,MEF2C,KCNV1,SCN5A,LGALS3,STXBP5L,FN1,TBC1D1,BVES,STXBP6,SCN8A,UBASH3B,OPHN1,BTBD9,MLC1,PFN2,IL18R1,GAS1,CA2,GATA2,CACNB2,PRELID1,SREBF1,LMAN2,CADPS2,STXBP1,RIMS2,NOS3,HMGCR,RHOQ,KCNQ3,TBC1D8B,RAPGEF4,PACSIN3,RYR2,WWC1,HIP1,SNAP25,PLCB1,TBC1D2,KCNK15,RPL28,SH3GL2,HK2,PLD1,CDH2,TRPC3,TESC,SFN,PLA2G4A,SORBS1,AKAP5,C4A,RGS20,PKP2,GRK6,NRXN1,DOCK2,PCLO,PPP1R9A,TBC1D30,SCIN,TLR3,UNC13B,CNKSR3,DACT1,REEP1,DAB2IP,MARCKS,PROS1,PDE4D,SCN2A,SYNGR3,RAB27B,HSPA2,KCNB2,SNAI2,SCN3A,GAB2,FZD1,DPP10,FER,CSN2,PFKFB2,KCNH5,PTPN6,FGF12,CHRNA6,GSTO1,PRKCQ,SYNJ2BP,AMIGO1,ATP1B1,RARRES2,CD40,ASPH,TBC1D16,C4BPB,SNCA,SMAD3,IRS2,RANBP2,CXCL10,PRKCB,GBP1,WFS1,PEMT,WWTR1,KCNG1,ITGA2,PAM,GRB10,BMPR1A,ATG5,SEPT5,STON2,CNTN1,MXI1,C1QTNF3,CD276,IPO5,APBB1,UBAC2,NKAIN2,ARL2,GAS6,P2RY1,NDFIP2,KCNC4,BMP6,NEDD4,MCU,NKX6-1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,SGK3,SGK1,TSPAN13,MYO6,TBC1D9,TNFRSF11A,SYK,FES,VEGFC,TRPM4,GSTM2,RAB3B,KDM5B,CACNA1E,SYBU,LITAF,CTTNBP2NL,TLR6,LRAT,MAP1B,GPLD1,ZIC1,DKK1,TRIB3,FGR,ICA1,GNAO1,MAP2K6,XBP1,BMP4,TBC1D4,IL9R,ATP2B4,CACNA2D1,PKIA,ABCG1,STOM |
| 5.282e-08 | -16.76 | GO_CIRCULATORY_SYSTEM_DEVELOPMENT | MSigDB lists | GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 761 | 121 | 17377 | 1707 |
ACVR1,ID1,RECK,ARHGAP22,GATA3,PKP2,COL18A1,ADAMTS6,NTRK3,NRXN1,PRKCA,TRPS1,TYMP,TGFBR3,RPS6KA2,SETDB2,EOMES,KCNAB1,ITGB3,DAB2IP,MARCKS,DNAH5,CPE,SLIT2,PDGFRB,SNAI2,CYP1B1,FZD1,MYLK3,FZD4,ADM2,TMEM65,ANK2,FGF12,YAP1,WNT11,CBY1,ACVR2B,SAV1,DSP,JAM3,FGFR1,WARS,GJC1,SMAD3,ARMC4,PDLIM3,HPSE,CCBE1,PTK7,PAM,HPGD,KLF5,SEMA3C,OXTR,BMPR1A,ATG5,UNC5B,NRP1,TPM1,MEF2C,PCSK5,HEY1,EFNB2,SCN5A,BMPR2,FN1,BVES,FZD8,OVOL2,SLC12A6,EPHB1,FHOD3,NEDD4,HOPX,GATA2,FLRT3,DSG2,ACTA2,LRP6,TSPAN12,SH3PXD2B,DYNC2H1,ERRFI1,SMAD6,SYK,NOS3,B9D1,VEGFC,MICAL2,VAV3,MSX1,SH2D2A,NR4A1,RAPGEF2,VLDLR,DCHS1,FHL2,RYR2,CALCRL,SMARCD3,PRICKLE1,SLITRK5,PRDM1,ZFPM2,HOXA1,LEPR,GPLD1,HEG1,ID3,FAT4,FBN1,PRCP,HEYL,XBP1,EGFL7,BMP4,DHCR7,SHOX2,CDH2,DDIT3 |
| 5.282e-08 | -16.76 | GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | MSigDB lists | GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 761 | 121 | 17377 | 1707 |
ACVR1,ID1,RECK,ARHGAP22,GATA3,PKP2,COL18A1,ADAMTS6,NTRK3,NRXN1,PRKCA,TRPS1,TYMP,TGFBR3,RPS6KA2,SETDB2,EOMES,KCNAB1,ITGB3,DAB2IP,MARCKS,DNAH5,CPE,SLIT2,PDGFRB,SNAI2,CYP1B1,FZD1,MYLK3,FZD4,ADM2,TMEM65,ANK2,FGF12,YAP1,CBY1,WNT11,ACVR2B,SAV1,DSP,JAM3,FGFR1,WARS,GJC1,SMAD3,ARMC4,HPSE,PDLIM3,CCBE1,PTK7,PAM,HPGD,KLF5,SEMA3C,OXTR,BMPR1A,ATG5,UNC5B,NRP1,TPM1,MEF2C,PCSK5,HEY1,EFNB2,SCN5A,FN1,BMPR2,BVES,FZD8,SLC12A6,OVOL2,EPHB1,NEDD4,FHOD3,HOPX,GATA2,FLRT3,DSG2,LRP6,ACTA2,TSPAN12,SH3PXD2B,DYNC2H1,ERRFI1,SMAD6,SYK,NOS3,VEGFC,B9D1,MICAL2,VAV3,MSX1,SH2D2A,NR4A1,RAPGEF2,DCHS1,VLDLR,FHL2,CALCRL,SMARCD3,RYR2,SLITRK5,PRICKLE1,PRDM1,ZFPM2,LEPR,HOXA1,GPLD1,HEG1,ID3,FAT4,FBN1,PRCP,HEYL,XBP1,EGFL7,BMP4,SHOX2,CDH2,DHCR7,DDIT3 |
| 5.453e-08 | -16.72 | humerus | COSMIC cancer mutations | humerus | 560 | 95 | 17385 | 1698 |
ARHGAP26,PPP4R4,PPFIBP2,RHPN2,ENAH,CTBP2,TDRKH,DDR1,PCLO,SLC19A2,HMCN1,DDX60L,DOCK2,ZFYVE9,FSTL5,EYA4,PCDH7,FKBP9,SPEG,GPRIN1,UNC13B,PPFIA2,MAGEA3,ZNF521,KIAA1614,FHIT,PPP2R2B,PCOLCE2,MDH1B,TLN2,TLR4,TSHR,SNX10,SLIT2,KCNB2,GLDC,TBC1D8,GPM6A,KCNIP3,EVL,DCC,CAP2,FGF12,ROR1,RAB38,ZDHHC14,TTLL7,GPC6,METAP1D,TMEM132B,ARHGAP21,KCNMB4,COBL,TENM1,FARP1,WDFY4,TPD52L1,FHOD3,HSPA12B,SLC35F1,RSL24D1,CHN2,FRAS1,GAS2L3,PRKG1,FMNL2,KIAA1211,HMGCR,DLGAP1,CRIM1,RNF170,COL4A4,ESRRG,PARD3B,CYTH3,GRID1,RYR2,ST6GALNAC3,SDK1,ZFPM2,KHDRBS2,NAALADL2,CTIF,NEGR1,BEX4,GPR37,DDAH1,PLEKHH2,SH3GL2,ADAMTS3,PTPRN2,PLD1,SEMA3A,TBC1D4,XKR4 |
| 5.661e-08 | -16.69 | V$TAL1BETAITF2_01 | MSigDB lists | V$TAL1BETAITF2_01 | 237 | 51 | 17377 | 1707 |
BCL11B,PHACTR3,KLF8,SORBS1,FGF13,ATP8A1,ARHGAP22,RASL11B,BCL6B,PRDM8,CADM2,SEL1L3,IKZF2,ARHGAP44,FOXP2,NUMBL,KCTD15,MAP1A,SCN1B,SCARF2,TRIM3,MAP7,HRK,RRAS2,GFI1,CPE,C15orf41,GFRA1,NEB,NDUFA4L2,MARK1,WWC1,ZFPM2,FBXO36,FNDC3A,MBNL2,PLCB1,HOXA1,TSKU,HTR7,SMAD3,DDAH1,NSD1,ITGBL1,B3GALT2,NXPH4,ZBTB20,SERPINI1,SHOX2,MID1,DDIT3 |
| 5.695e-08 | -16.68 | PH | smart domains | SM00233 | 261 | 59 | 9493 | 1056 |
ARHGAP26,FARP1,DNM3,RASAL2,ARHGEF11,GRB14,PLEKHA5,ARHGAP22,OPHN1,PSD3,PHLDA2,DOK5,TIAM2,RALGPS2,MCF2L,AFAP1L2,DAB2IP,RTKN2,CADPS2,IPCEF1,GAB2,PHLDB2,VAV3,ARAP2,SH3BP2,ARHGEF28,SKAP2,MYO10,PLEKHA8,MCF2L2,CYTH3,ASAP3,PREX1,SPATA13,RASA3,OBSCN,FERMT2,AGAP2,CDC42BPA,PLEKHA1,SNTB1,SKAP1,GRK3,PLEKHB1,ARHGEF26,TBC1D2,IRS2,ARHGAP21,PLEKHH2,AKT3,RASGRF2,OSBPL5,PLEKHG1,GRB10,PLD1,IQSEC2,OSBPL6,KIF1B,DOCK9 |
| 5.914e-08 | -16.64 | QI_HYPOXIA | MSigDB lists | QI_HYPOXIA | 135 | 35 | 17377 | 1707 |
MXI1,RHOBTB1,PKP2,NDRG2,NRN1,IL13RA1,SCD,FAM117B,KIF21B,SLC19A2,DDIT4,CYP51A1,ALDOC,REEP1,BNIP3,DUSP1,FZD1,IGFBP3,PDK1,MVD,CAPN5,VLDLR,DYRK1B,HPSE,INSIG1,PLOD2,P4HA2,ACER2,ALDOA,HK2,MPP2,SQLE,P4HA1,HK1,MBOAT2 |
| 6.191e-08 | -16.60 | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN | MSigDB lists | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN | 185 | 43 | 17377 | 1707 |
TNIK,PLSCR4,TTC39B,ATP8A1,ITGA6,CYP4V2,LRRCC1,PSD3,TJP1,MECOM,HSPA12B,TGFBR3,CA2,ZNF354A,GATA2,ABCA5,MARVELD2,DSG2,PRELID2,ITGB3,TSC22D1,NBEA,MARCH3,NAP1L3,CADPS2,WWC2,MED12L,EPB41L5,PFKFB2,NFIA,TTC30A,C3orf70,ENTPD1,HLF,IGIP,KIAA0355,PLXDC2,RBPMS2,HGF,FNBP1L,MLLT3,HACE1,PHC1 |
| 6.276e-08 | -16.58 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | 836 | 130 | 17377 | 1707 |
ACSL1,ADAL,RECK,ASS1,TUBE1,ENAH,ITPR2,CHAC1,PRKCA,AARS,SIPA1L2,IKZF5,PMAIP1,RAP2A,TMEM143,LIN7A,CTTN,PTPRE,PRKACB,DBN1,SLC3A2,CD55,SESN2,ERGIC1,ABCC4,ALDH1L2,ATOX1,LRMP,DEPTOR,NFE2L1,BNIP3L,EFHC1,PLEKHA1,MFSD6,SLC7A1,CCDC169,ADRB1,NRP1,LPP,CARS,GPT2,RGS16,INPPL1,CELSR1,ALOX5AP,ITPRIP,SEC24D,ZCCHC24,SLC36A4,PHGDH,GRPEL2,DDIT4,SLC7A11,NCEH1,FMNL2,PLEKHA8,VLDLR,TCEA3,MAFB,HIP1,SHISA2,CDC42BPA,ARRDC4,TAF4B,MBNL2,TMEM154,KIAA0355,HOXD13,DIRC2,SCAMP1,PLEKHA5,ZNF311,MYO1B,TMEM170B,KIF21B,LACC1,EPB41L3,ASNS,ZNF438,BCL6,MAP7,PDE4D,CTH,GARS,TUBA1A,TMEM65,TES,NPM3,SFXN4,PREX1,ATF3,CD40,TPK1,BCL11A,WARS,ZNF569,BATF3,SLC39A14,GRB10,PSPH,HACE1,BLVRB,CBS,SLC12A6,INPP1,SEL1L3,NEDD4,EIF1,STC2,FIG4,KLF9,ERRFI1,PCK2,SYK,GSTM2,SH3BP2,ARAP2,RAPGEF2,FOXN3,PHACTR2,MARS,SNTB1,PTPRC,CEBPB,CD37,TRIB3,SRD5A3,SLC22A15,TBC1D4,KIF1B |
| 6.321e-08 | -16.58 | biliary_tract | COSMIC cancer mutations | biliary_tract | 15787 | 1599 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,COL6A2,GAPDH,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,FAM201A,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZNF440,SMTN,HS3ST5,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 6.405e-08 | -16.56 | GTPase regulator activity | molecular function | GO:0030695 | 316 | 62 | 17224 | 1680 |
ARHGAP26,RGS16,STXBP5L,RASAL2,TBC1D1,ARHGEF11,DOCK1,ARHGAP22,IPO5,OPHN1,RGS20,ARL2,GPSM2,FAM13A,RGS7,TBC1D30,DOCK2,TIAM2,ARHGAP44,SYDE2,TBC1D19,CHN1,ADPRHL1,SIPA1L2,RGS17,CHN2,SRGAP1,RALGAPA2,DAB2IP,TBC1D9,ERRFI1,SLIT2,RASGRP1,TBC1D8,VAV3,RIN2,TNK2,ARAP2,SESN2,TBC1D8B,RAPGEF2,LRRK2,ELMOD1,ASAP3,GPSM1,PREX1,RASA3,AGAP2,WNT11,ARHGAP32,PLCB1,TBC1D16,TBC1D2,RANBP2,ARHGAP21,ADGRB3,NCKAP1L,SH3BP4,RGS10,ARHGAP28,NRP1,TBC1D4 |
| 6.588e-08 | -16.54 | GO_SYNAPSE_PART | MSigDB lists | GO_SYNAPSE_PART | 590 | 99 | 17377 | 1707 |
DOC2A,DMXL2,DNM3,SCAMP1,AKAP5,PRSS12,GRIK2,SYT12,RGS20,ADD2,KCTD12,NRXN1,CANX,PRR7,PCLO,CBLN1,PPP1R9A,NCS1,CTNNA2,EPB41L3,UNC13B,KCNN2,CHRNA5,PPFIA2,LIN7A,MARCKS,CTTN,SYNGR3,CPE,GPM6A,CAP2,ANK2,DNAJC6,LRRK2,SHANK2,CHRNA6,NLGN4X,PRKAR2B,SNCA,CAMK2N1,TRIM9,SEPT5,APBA2,CTTNBP2,MAGI2,LZTS1,STON2,CTNND2,MEF2C,SV2B,SLC6A9,FARP1,BMPR2,GABRB2,LRP4,APBB1,EPS8,OPHN1,CLSTN2,GABRG2,PSD3,GABRR2,SLC1A3,P2RY1,APBA1,PFN2,ARHGAP44,KCNJ4,SEMA4F,FLRT3,GRIP1,MPDZ,CADPS2,BNIP3,STXBP1,RIMS2,ATP2B1,CHRM3,DLGAP1,SLC40A1,DISC1,RAB3B,HOMER2,GRID1,ARHGAP32,RABAC1,SNAP25,BAIAP2,CPEB1,MAP1B,HOMER3,GRIK4,ICA1,PTPRN2,GRIN2D,DLG2,MME,SNPH,ATP1A3 |
| 6.637e-08 | -16.53 | cell leading edge | cellular component | GO:0031252 | 385 | 70 | 18223 | 1724 |
AMOTL1,ENAH,SNX9,RAC3,PPP1R9A,CTNNA2,TIAM2,EPB41L3,ITGB3,CTTN,TLN2,PACSIN1,DOCK8,PHLDB2,FER,EVL,ATF4,WLS,VIM,PLEKHA1,ARHGEF26,GABARAPL1,SLC39A14,GSN,PTPRJ,SH3RF1,ABI3,SPRY4,TPM1,COBL,WASF3,MYO1D,INPPL1,ROBO2,SLK,EPS8,APBB1,PSD3,GABRG2,KCNC4,ARHGAP44,ABLIM1,ACTA2,MYO6,SPRY2,ATP2B1,PDLIM7,PAK1,EPB41L5,PXN,MYO10,PTPN13,CYTH3,SPATA13,ASAP3,WWC1,FERMT2,CDC42BPA,PALLD,BAIAP2,FGR,PLEKHH2,MYADM,RIPOR2,FAT1,MPP2,MCC,CDH2,TESC,SHTN1 |
| 6.765e-08 | -16.51 | GNF2_RTN1 | MSigDB lists | GNF2_RTN1 | 49 | 19 | 17377 | 1707 |
GPM6A,TRIM2,ATP9A,ANK2,DNAJC6,ADCY1,KIF5C,DOCK3,NRXN1,RGS7,DYNC1I1,FAM131B,CAMK2N1,RTN1,GNAO1,NAP1L3,STXBP1,KIF1B,CTNND2 |
| 6.833e-08 | -16.50 | PDZ | prosite domains | PS50106 | 144 | 38 | 12060 | 1278 |
FRMPD3,ARHGEF11,TJP1,APBA1,RADIL,PPP1R9A,TIAM2,SIPA1L2,PDZD8,PDZD7,CNKSR3,GRIP1,LIN7A,MPDZ,MAST4,RIMS2,PDLIM7,INTU,SYNPO2,PARD3B,RAPGEF2,PTPN13,MPP1,SHANK2,DEPTOR,PREX1,SYNJ2BP,SNTB1,MAGI3,ARHGAP21,PDLIM3,MPP7,AHNAK2,MPP2,DLG2,APBA2,MAGI2,MAST1 |
| 7.366e-08 | -16.42 | GO_NUCLEOSIDE_TRIPHOSPHATASE_REGULATOR_ACTIVITY | MSigDB lists | GO_NUCLEOSIDE_TRIPHOSPHATASE_REGULATOR_ACTIVITY | 315 | 62 | 17377 | 1707 |
ARHGAP26,RGS16,STXBP5L,RASAL2,ARHGEF11,DOCK1,TBC1D1,ARHGAP22,IPO5,OPHN1,RGS20,ARL2,GPSM2,RGS7,FAM13A,PFN2,DOCK2,TBC1D30,ARHGAP44,GRPEL2,TIAM2,SYDE2,TBC1D19,ADPRHL1,CHN1,RGS17,BAG3,SIPA1L2,CHN2,SRGAP1,RALGAPA2,DAB2IP,IQGAP3,TBC1D9,ERRFI1,SLIT2,TBC1D8,TNK2,VAV3,RIN2,ARAP2,TBC1D8B,RAPGEF2,LRRK2,ASAP3,PREX1,GPSM1,ELMOD1,RASA3,WNT11,AGAP2,ATP1B1,ARHGAP32,PLCB1,TBC1D16,TBC1D2,ARHGAP21,NCKAP1L,RGS10,SH3BP4,ARHGAP28,TBC1D4 |
| 7.415e-08 | -16.42 | GO_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1513 | 210 | 17377 | 1707 |
FGF13,GATA3,NPM1,STAT5B,ITPR2,CHAC1,DOCK3,PRKCA,CA8,RAC3,NCS1,STK24,RND2,TGFBR3,RPS6KA2,PMAIP1,AKAP7,RAP2A,RAB26,RCAN3,TLR4,RAPGEF5,RASGRP1,PDGFRB,CYP1B1,TNK2,SESN2,ATF4,MARK1,DCDC1,ANK2,LRRK2,DEPTOR,YAP1,PRKAR2B,FGF17,PLEKHA1,SAV1,BATF,SGK2,GSN,RASGRF2,PLK2,ERN1,TNFRSF1A,BBC3,MAPK13,PIK3C2B,DIRAS1,INPP5F,OXTR,MEF2C,TYRO3,PRKAA2,LATS2,CELSR1,RHOBTB1,DHCR24,RASL11B,TJP1,TNFRSF19,DOK5,DDIT4,CHN1,IGF1R,RALGPS2,MYC,PRKG1,ADCY6,GRIP1,BNIP3,NCAM1,MAST4,GFRA1,RIMS2,ZNF385A,NOS3,FGFR4,PAK1,IL17RD,DISC1,RHOQ,STAT4,DCHS1,RAPGEF4,DUSP9,RYR2,WWC1,CDC42BPA,PLCB1,MAPKAPK2,PLAGL1,PKN3,RAB31,PLD1,SFN,DOCK9,BTC,AMOTL1,RASAL2,IL15,RHOD,DOCK1,MAPK4,CHUK,LCP2,TNKS1BP1,DOCK2,PCLO,PPP1R9A,TIAM2,TLR3,PDZD8,UNC13B,BCL6,DAB2IP,FHIT,PDE4D,SCN2A,ARL4D,RAB27B,PERP,DOCK8,GAB2,FER,PDK1,KCNH5,PTPN6,FGF12,PREX1,ADCY1,GSTO1,PRKCQ,SYNJ2BP,ATP1B1,RAB38,CD40,DOCK5,ASPH,FGFR1,MAGI3,IRS2,NRG3,PRKCB,EIF4EBP1,WWTR1,TNFSF15,MAPK10,RAB30,HACE1,MAST1,TNIK,EDA2R,ARHGEF11,REL,ARL15,EPS8,MCTP2,ARL2,RASD1,GAS6,PKN1,RGS7,MCU,CHN2,BHLHA15,GPR155,MCF2L,PCBP4,RASD2,PRKCD,GHR,SGK3,SGK1,IQGAP3,MYO6,RRAS2,SYK,DUSP1,MOB1B,VAV3,RIN2,GSTM2,RAB3B,RAB6B,RAPGEF2,NUAK2,RASA3,AGAP2,GUCY1A2,TLR6,CEBPB,TRIB3,DDAH1,TIFA,DOCK7,FAT4,RND3,AKT3,MAP2K6,XBP1,NEK11,TUFT1,GRIN2D,LRRK1,GEM,DOCK6,DDIT3,LARP1,BTRC |
| 7.806e-08 | -16.37 | central_nervous_system-brain-glioma | COSMIC cancer mutations | central_nervous_system-brain-glioma | 15942 | 1611 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,OTX1,CHUK,KCTD12,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,RBM11,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,ANKRD20A2,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 7.822e-08 | -16.36 | ESC_V6.5_UP_LATE.V1_UP | MSigDB lists | ESC_V6.5_UP_LATE.V1_UP | 180 | 42 | 17377 | 1707 |
FARP1,RASAL2,PRSS12,BVES,RECK,FZD8,CMTM8,VAMP8,IGF2BP2,HBE1,SEL1L3,SATB1,GAS1,CYP26A1,EOMES,SOAT2,FAM107B,ZNF521,OPN3,MYO6,PRKACB,HBG2,CD55,WLS,SLC39A8,PTPN13,PRICKLE1,DKK1,PDLIM3,PLAGL1,SH3RF1,PLOD2,P4HA2,P4HA1,KIF21A,RNF130,UNC5B,CDH2,PURG,FOXA1,OCLN,HEY1 |
| 8.013e-08 | -16.34 | DOANE_RESPONSE_TO_ANDROGEN_DN | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_DN | 226 | 49 | 17377 | 1707 |
EFNB2,ENO2,EPS8,GATA3,KIF5C,FAM198B,HERC6,FAM110B,PHLDA2,RTN1,KMO,PCBP4,PRKCD,LRP6,MARCKS,SERPINH1,SMAD6,MAST4,ZFP36L2,IGFBP3,SNX7,MN1,BCL7A,EVL,SLC27A2,WLS,MPP1,ASAP3,PALLD,C4orf19,ASPH,PLCB1,DSP,SMAD3,ZNF93,TDO2,PLOD2,PELI2,RGS10,RAI14,SEMA3C,PAX9,SUSD4,SIX2,CTNND2,TPT1,STOM,SNPH,PHC1 |
| 8.061e-08 | -16.33 | postsynapse | cellular component | GO:0098794 | 448 | 78 | 18223 | 1724 |
DNM3,CACNG3,GRIK2,ADD2,KCTD12,CANX,PRR7,PCLO,PPP1R9A,CBLN1,CTNNA2,NCS1,EPB41L3,CHRNA5,KCNN2,LIN7A,CTTN,GPM6A,CAP2,ANK2,SHANK2,DNAJC6,LRRK2,NLGN4X,CHRNA6,PRKAR2B,SNCA,CAMK2N1,MAP2,RGS10,PTPRS,APBA2,CTTNBP2,MAGI2,LZTS1,MEF2C,FARP1,BMPR2,GABRB2,APBB1,LRP4,OPHN1,PSD3,GABRG2,CLSTN2,P2RY1,GABRR2,APBA1,ARHGAP44,NEDD4,KCNJ4,SEMA4F,GRIP1,BNIP3,CADPS2,MPDZ,STXBP1,ATP2B1,CHRM3,DLGAP1,DISC1,LZTS3,HOMER2,GRID1,HIP1,ARHGAP32,SNAP25,CPEB1,BAIAP2,MAP1B,HOMER3,DAGLA,GRIK4,ADGRB3,MPP2,DLG2,GRIN2D,CDH2 |
| 8.497e-08 | -16.28 | regulation of multicellular organismal development | biological process | GO:2000026 | 2018 | 262 | 17256 | 1658 |
ACVR1,LGR4,LDLR,GATA3,STAT5B,PRKCA,RAC3,NCS1,STK24,TRPS1,SKI,TYMP,TGFBR3,RAP2A,PACSIN1,NKX2-1,MEIS2,ACVR1C,DCC,LRRK2,FEZ1,AGO4,ACVR2B,SAV1,GPC6,ENPP1,NCKAP1L,CCBE1,PLK2,BMP1,SEMA3C,SERPINI1,INPP5F,NRP1,SPART,VASH2,MEF2C,EFNB2,CELSR1,PTPRD,FOXG1,IL17D,CHN1,CNTN4,APLF,MYC,FLRT3,PRELID1,GRIP1,TOX,TSPAN12,RIMS2,GPR161,HMGCR,EPB41L5,PTCH2,ENAM,BDNF,DISC1,PNP,VLDLR,NSD2,SMARCD3,SNAP25,PLCB1,THBS4,SFMBT1,HOXD13,CDH2,SHTN1,EPHA3,NBL1,DNM3,PLXNA2,NRXN1,TLR3,DACT1,DAB2IP,ZNF365,FZD1,SSH3,FZD4,ADM2,NKX3-2,SHANK2,PREX1,PRKCQ,WNT11,ATOH1,FGFR1,SNCA,CXCL10,IKZF3,PRKCB,APELA,WWTR1,BMPR1A,COBL,WASF3,ROBO2,PLAG1,GAS6,EPHB1,ZNF219,GDPD5,PHLDA2,NEDD4,ADGRB2,LRRN1,FIG4,YBX3,ERRFI1,GFI1,SPRY2,ZFP36L2,FES,TRPM4,VEGFC,LZTS3,RAPGEF2,RACK1,CEBPB,ID3,TERT,AKT3,XBP1,BMP4,SHOX2,DDIT3,FOXA1,TLL2,TRIM16,FGF13,LILRB1,F3,RND2,EOMES,GRHL1,CTTN,TLR4,IL1RAP,SLIT2,PDGFRB,RASGRP1,PRKACB,CYP1B1,DBN1,GCNT2,COL4A3,CEMIP2,YAP1,ROR1,HPSE,GPRC5B,MAP2,TNFRSF1A,DLX2,OXTR,TNFSF4,MAGI2,MLLT3,UST,BCL11B,RUNX2,LGALS3,FN1,UBASH3B,CHADL,SPINK5,EFEMP1,NUMBL,SEMA4F,CA2,GATA2,ADCY6,LRP6,NOS3,PAK1,SLITRK2,MSTN,EFNA3,MAFB,SLITRK5,SDK1,PRDM1,BAIAP2,NEGR1,ADGRB3,HEYL,CSF1,HK2,SEMA3A,TESC,SFN,SIX2,PRKN,ZSWIM5,ID1,IL15,CELSR3,RBFOX2,HECW2,NTRK3,SEMA6A,CBLN1,PPP1R9A,SCIN,ADGRL1,BCL6,ACVR2A,ZNF488,SNAI2,CTH,GLI1,PHLDB2,CSN2,PTPN6,VIM,AMIGO1,SYNJ2BP,CD40,WARS,SMAD3,NRG3,PTK7,PTPRS,HGF,HEY1,CNTN1,TNIK,BMPR2,LRP4,APBB1,CLSTN2,OVOL2,BMP6,ARHGAP44,NKX6-1,FOXP2,SCN1B,KIAA0319,TFAP2A,PRICKLE2,SH3PXD2B,IQGAP3,SLC45A3,SYK,TESPA1,MSX1,KDM5B,PRICKLE1,ZFPM2,DKK1,MAP1B,DDAH1,DOCK7,MYADM,FAT4,FBN1,CTSV,PAX9,MYRF |
| 8.844e-08 | -16.24 | GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN | MSigDB lists | GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN | 168 | 40 | 17377 | 1707 |
PPP4R4,PDE1B,LGALS3,SCAMP1,ATP8A1,UBASH3B,MLF1,DHCR24,YPEL2,GATA3,NDRG2,LRRC49,CANX,ADSSL1,STK24,PLS3,EPCAM,HMGCS1,SETDB2,AKAP7,BACE2,STARD4,TSC22D1,TSPAN13,PCK2,MOB1B,MID2,EIF4E3,PNP,TMEM43,TDRD3,SLC36A1,AGPAT4,ATF3,ARRDC4,ASPH,EML1,GALNT3,ICA1,SH3BP4 |
| 8.997e-08 | -16.22 | GO_POSTSYNAPSE | MSigDB lists | GO_POSTSYNAPSE | 367 | 69 | 17377 | 1707 |
DNM3,AKAP5,GRIK2,RGS20,ADD2,KCTD12,CANX,PRR7,PCLO,CBLN1,PPP1R9A,NCS1,CTNNA2,EPB41L3,KCNN2,CHRNA5,LIN7A,MARCKS,CTTN,GPM6A,ANK2,CAP2,DNAJC6,LRRK2,SHANK2,CHRNA6,NLGN4X,PRKAR2B,SNCA,CAMK2N1,CTTNBP2,MAGI2,LZTS1,CTNND2,MEF2C,FARP1,BMPR2,GABRB2,EPS8,APBB1,LRP4,OPHN1,CLSTN2,PSD3,GABRG2,P2RY1,SLC1A3,GABRR2,ARHGAP44,KCNJ4,SEMA4F,GRIP1,CADPS2,BNIP3,MPDZ,CHRM3,DLGAP1,DISC1,HOMER2,GRID1,ARHGAP32,CPEB1,BAIAP2,MAP1B,HOMER3,GRIK4,DLG2,GRIN2D,ATP1A3 |
| 1.010e-07 | -16.11 | CAMP_UP.V1_DN | MSigDB lists | CAMP_UP.V1_DN | 188 | 43 | 17377 | 1707 |
MPZL3,GNG12,ENO2,PTPRD,ATP9A,ATP8A1,BACE1,PRDM8,TJP1,SEL1L3,KBTBD11,UBTD2,PCLO,PLS3,EPB41L3,ABLIM1,FRY,RASD2,RAP2A,TSC22D1,TRPC1,TLN2,STXBP1,ATP2B1,PFKFB4,ATL1,FOXN3,PRDM1,PALLD,RERE,PTPRC,IQCK,DDAH1,INSIG1,BACH2,MAP2,AKT3,PAM,RAB31,GEM,TANC2,PKIA,ATP2B4 |
| 1.031e-07 | -16.09 | AGC-kinase_C | interpro domains | IPR000961 | 55 | 20 | 18492 | 1811 |
LATS2,PRKCQ,GRK6,CDC42BPA,SGK2,PKN1,PRKCA,GRK3,RPS6KA2,PKN3,PRKCB,AKT3,PRKCD,PRKG1,SGK3,SGK1,PRKG2,MAST4,PRKACB,MAST1 |
| 1.079e-07 | -16.04 | ELVIDGE_HYPOXIA_BY_DMOG_UP | MSigDB lists | ELVIDGE_HYPOXIA_BY_DMOG_UP | 126 | 33 | 17377 | 1707 |
MXI1,ENO2,ZNF395,SFXN3,FAM13A,PRKCA,DDIT4,ALDOC,STC2,OPN3,BNIP3,LIMCH1,MET,IGFBP3,VEGFC,QSOX1,PDK1,VLDLR,BNIP3L,AK4,ATF3,ASPH,FAM162A,ISG20,P4HA2,SRD5A3,HK2,PAM,AHNAK2,P4HA1,CSRP2,HEY1,RRAGD |
| 1.115e-07 | -16.01 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | 65 | 22 | 17377 | 1707 |
EXPH5,MICAL2,PPP1R3D,TNIK,MSTN,C3orf52,KCTD12,DDIT4,PLK2,REEP1,MARCKS,PDE4D,SPRY4,MOXD1,NEB,ZFP36L2,COBL,PKIA,ATP2B4,LARP1,TBC1D8,IGFBP3 |
| 1.162e-07 | -15.97 | negative regulation of cell communication | biological process | GO:0010648 | 1379 | 190 | 17256 | 1658 |
ACVR1,DUSP8,LGR4,GRIK2,GATA3,NDRG2,CHAC1,ABHD6,KREMEN1,EYA4,SKI,TGFBR3,ZFYVE28,CHRDL1,CTTN,EPHB6,PTPRE,TLR4,ENO1,SLIT2,PRKACB,PDGFRB,NKX2-1,SESN2,ACVR1C,LRRK2,DEPTOR,YAP1,ROR1,PLEKHA1,SESN1,TSKU,GNAI1,ENPP1,INSIG1,SH3RF1,PLK2,INPP5F,SPRY4,DLX2,NRP1,UNC5B,PPARGC1A,SPART,MAGI2,MLLT3,PRKAA2,TYRO3,RGS16,LATS2,RUNX2,STXBP5L,LGALS3,ITGA6,UBASH3B,RASL11B,MECOM,DDIT4,IGF1R,BCHE,GATA2,MYC,FLRT3,C1QL4,PRELID1,SREBF1,LRP6,STXBP1,BARX1,GPR161,ZNF385A,NOS3,RNF152,HMGCR,PTCH2,FGFR4,MSTN,DUSP9,WWC1,STRADB,SHISA2,PRDM1,HERPUD1,RIPOR2,SH3GL2,PMEPA1,HEYL,SH3BP4,EGFL7,CDH2,EPHA3,PRKN,NBL1,BTC,RASAL2,RGS20,NTRK3,TMEM170B,DDR1,PIBF1,PPP1R9A,CBLN1,CYP26A1,TLR3,CNKSR3,DACT1,MAGEA3,BCL6,DAB2IP,WWC2,MET,SNAI2,GLI1,CTH,IGFBP3,FZD1,PRAME,NOP53,PTPN6,SHANK2,PREX1,RNF125,NLGN4X,PRKCQ,WNT11,CBY1,GSTO1,ATF3,SYNJ2BP,FGFR1,SNCA,CAMK2N1,SMAD3,PTPRJ,PRKCB,GBP1,RBPMS2,WFS1,ASIC1,WWTR1,MAP3K21,RGS10,DUSP19,PTPRS,HGF,GRB10,HEY1,DYRK3,IGFBP6,C1QTNF3,PAK5,GRB14,LRP4,NOTUM,GAS6,EPHB1,RGS7,GDPD5,ARHGAP44,NEDD4,RAB11FIP5,RGS17,PRKCD,SGK3,YBX3,ERRFI1,SMAD6,SPRY2,DUSP1,GSTM2,LITAF,PRICKLE1,RASA3,RACK1,TLR6,SMPDL3B,DKK1,PTPRC,TRIB3,MYADM,TERT,FBN1,XBP1,MCC,PCGF2,BMP4,DDIT3,ATP2B4,BTRC,TPT1 |
| 1.188e-07 | -15.95 | MODULE_94 | MSigDB lists | MODULE_94 | 355 | 67 | 17377 | 1707 |
EXPH5,ZNF516,CACNG3,GRIK2,RBFOX2,QPRT,MOK,TGFBR3,AKAP7,PPFIBP1,ACVR2A,PTPRE,GATM,RASGRP1,GLI1,IGFBP3,ITGB7,ABCC4,CR2,PRKCQ,ATF3,ROR1,F12,ASPH,C4BPB,CXCL10,GPRC5B,PEMT,ATP7B,ITGA2,SERPINI1,SEPT5,TYRO3,GNG12,ARHGEF11,CYP2J2,BIK,EPS8,APBB1,GABRG2,OVOL2,EPHB1,APBA1,GDPD5,PPP2R3A,HOPX,CHN2,PCBP4,COL9A2,PDLIM7,KCNQ3,SLC27A2,SH2D2A,PTPN13,VLDLR,SMARCD3,PLS1,C1R,ARHGAP32,SKAP1,STEAP1,ICA1,THBS4,RAI14,DYNC2LI1,NKX2-8,ATP2B4 |
| 1.189e-07 | -15.94 | GO_MEMBRANE_REGION | MSigDB lists | GO_MEMBRANE_REGION | 1094 | 160 | 17377 | 1707 |
GRIK2,LDLR,NCS1,NOS1AP,EPCAM,AKAP7,SLC22A18,MARVELD2,ITGB3,LIN7A,CNNM2,CTTN,PACSIN1,MYRIP,CPE,PDGFRB,TNK2,CD55,SLC3A2,ATF4,ABCC4,TGFA,WLS,ANK2,LRRK2,ABCC2,PRKAR2B,PLEKHA1,GNAI1,ENPP1,GPRC5B,HPSE,ATP7B,TNFRSF1A,INPP5F,OXTR,SPRY4,UNC5B,TPM1,LZTS1,RGS16,SCN5A,FN1,BVES,GABRB2,ITGA6,TJP1,SLC1A3,MLC1,BBS9,CA2,SEMA4F,EEF2,FLRT3,LRP6,ADCY6,GRIP1,MPDZ,CADPS2,SLCO4C1,LRP3,RIMS2,LRP12,CHRM3,GPR161,NOS3,EPB41L5,PAK1,DISC1,RHOQ,MYO10,HOMER2,VLDLR,SPATA13,WWC1,SNAP25,CPEB1,GRIK4,FCHO2,CDH17,SH3BP4,PLD1,CDH2,TESC,AMOTL1,SORBS1,TCTN2,ST14,AKAP5,KCTD12,NRXN1,LCP2,PRR7,DDR1,CBLN1,CTNNA2,EPB41L3,CHRNA5,MAP7,PDE4D,MET,SERPINH1,RAB27B,TMEM67,SHANK2,ADCY1,CHRNA6,NLGN4X,ATP1B1,DSP,GABARAPL1,CAMK2N1,PTPRJ,PEMT,HPGD,BMPR1A,CNTN1,TNIK,MYO1D,BMPR2,ROBO2,LRP4,EPS8,APBB1,CLSTN2,PSD3,GABRG2,GABRR2,SLC12A6,P2RY1,EPHB1,NEDD4,KCNJ4,DSG2,EHD3,PRKG2,MYO6,SPRY2,ATP2B1,DLGAP1,SLC40A1,RAPGEF2,GRID1,FERMT2,ARHGAP32,TLR6,LEPR,HOMER3,PTPRC,FGR,MYADM,SLC7A5,GRIN2D,DLG2,HK1,SLC16A10,OCLN,ATP2B4,SNPH,STOM |
| 1.198e-07 | -15.94 | TGCCAAR_V$NF1_Q6 | MSigDB lists | TGCCAAR_V$NF1_Q6 | 676 | 109 | 17377 | 1707 |
EPHA3,NUDT10,AMOTL1,ACVR1,TTC39B,C4A,PTPN21,PLXNA2,NDRG2,NTRK3,IKZF2,SEMA6A,HECTD2,PCDH7,TRPS1,PLS3,SLC22A17,DACT1,ANKFN1,BCL6,FAM133A,NAP1L3,ARL4D,MET,SNX10,KCNB2,GAB2,VNN2,CD55,MEIS2,GCNT2,COL4A3,FZD4,PRDM13,ADCY1,NFIA,ACO1,ROR1,WARS,IRS2,ZNF711,INHBC,IFT81,KLF12,BACH2,PTK7,TIGD4,B3GALT2,HPGD,HGF,SPRY4,LIFR,NR3C2,FRMD5,C1QTNF3,FAM124A,IGFBP6,ESRP1,JDP2,OPHN1,ATP6V1E2,PRDM8,ZIC2,PGAP1,GRPEL2,NEDD4,MCU,MECOM,DDIT4,FOXP2,NUMBL,MAP1A,CACNB2,PCBP4,FLRT3,ZIC5,GHR,FAM107B,CPXM2,NCAM1,MOXD1,PRR16,MAST4,TSPAN9,RBMS2,CKAP4,BDNF,RIN2,MSTN,COL4A4,ESRRG,RAPGEF4,PEX5L,AGAP2,SKAP1,PLCB1,GPLD1,ID3,MFSD2A,GNAO1,RAI14,DLG2,KIF21A,LRRK1,CERS1,SHOX2,DDIT3,BTRC,SIX2 |
| 1.260e-07 | -15.89 | cytoplasm | cellular component | GO:0005737 | 11448 | 1181 | 18223 | 1724 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,KIAA1217,BCAN,SNX9,ABHD6,SKI,TXNDC5,RAP2A,TMED9,PPP2R2B,COG3,CPE,SMIM20,EIF4E3,DCC,EXOC6B,DSTN,LRRK2,FEZ1,PRKAR2B,PYCR1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,INPP5F,TPM1,DNHD1,VASH2,SCN5A,TJP1,BTBD9,GPSM2,BBS9,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,CADPS2,FAM84B,ALPK1,DENND1C,MOXD1,FIGN,ZNF385A,FHL2,FASN,HIP1,ST6GALNAC3,SHISA2,SNAP25,ARRDC4,CLN5,SPATA7,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,SELENOM,CLMN,LAPTM4B,CDH2,SHTN1,GVINP1,DOCK9,MTG1,TFCP2L1,SCAMP1,SUGCT,ABHD13,ADD2,MAPK4,TLR3,ALDH1L1,MAGEA3,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,GABARAPL1,GJC1,SLC39A14,ARHGAP21,PDLIM3,WFS1,LAMB1,RAB30,CGB2,ANKRD13B,WDR17,GCAT,CKAP2,BACE1,FZD8,BIK,UBAC2,CBS,GAS6,EPHB1,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,OPLAH,LZTS3,RAB6B,RASA3,AK4,ATP11A,RPL12,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CCDC126,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,MGAT5B,FAM13A,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,SEC16B,AADAT,ITGB3,TBC1D32,TMEM143,JAKMIP2,ENO1,DBN1,KCNIP3,MARK1,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,SESN1,SPNS1,TRIM9,TCF7L1,INSIG1,KLF12,ERN1,AHNAK2,RRAGD,LONRF1,TYRO3,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZIC2,PFN2,DOK5,FHOD3,SPIRE1,RNF180,GALNT1,NUMBL,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,CKAP4,DPYSL5,NDUFA4L2,B3GLCT,MGAT4B,GPSM1,STRADB,OBSCN,BAIAP2,TBC1D2,PLD1,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,PPP1R9A,IDI1,TACC2,BCL6,ZDHHC23,MYH15,SNAI2,IGFBP3,RPS13,INTU,LRRC8B,TMEM65,TDRD3,ACO1,RNF125,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,KIZ,DYRK3,NECAB2,BMPR2,PAK5,KLHL13,MCTP2,RASD1,USP30,TTC1,TSC22D1,TFAP2A,SGK1,SYK,CES3,PCSK6,DUSP1,CRIP2,PRICKLE1,FERMT2,EXOG,PALLD,ILDR2,HOMER3,DKK1,DDAH1,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,PLBD2,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TYMP,ZFYVE28,PALD1,KCNS3,NDUFB8,THSD1,GLDC,GDAP1,ERGIC1,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,BMP1,DSEL,SERPINI1,MAPK13,SPRY4,NRP1,KLF8,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,HERC6,APBA1,MTUS1,ABLIM1,RALGPS2,SLC7A11,MYC,SREBF1,PRKG1,GRIP1,MAST4,COL9A2,GPR161,BOD1,RPL26,DISC1,SLC36A1,VLDLR,RAPGEF4,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,PLEKHH2,PELI2,THBS4,WDR19,DYNC2LI1,MPP2,SQLE,DHCR7,SMYD3,TCTN2,RHOD,MSR1,COL14A1,DDR1,TIAM2,ZFYVE9,CCDC120,ASNS,ERG28,ZNF438,POU5F1B,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,CBY1,TRIQK,ATP10D,ISG20,SNCA,PATJ,IKZF3,BEX3,TDO2,CCNA1,HPGD,MID1,STON2,COBL,HACE1,MYO1D,IGFBP6,EPS8,KIF5C,HERC5,NDFIP2,TPD52L1,INPP1,PHLDA2,GSAP,GPR155,RMDN2,DYNC2H1,CERS4,ERRFI1,SMAD6,B4GALT6,SLC40A1,VAV3,PXN,ALDH2,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,TMEM126A,ZDHHC15,UCHL3,TERT,MCC,SVIL,LRRK1,CERS1,DDIT3,LARP1,ACSL1,ACTL8,PTPN21,HMCN1,CHST10,GSDME,ADPRHL1,PPM1E,CTTN,MYRIP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,PPARGC1A,MAGI2,PCSK5,GPT2,GPR63,SV2B,MOCOS,ZNF395,RHOBTB1,SCART1,STXBP6,FBXO4,SCD,CHSY1,SPINK5,EEF2,SLC30A4,ZNF354A,INAVA,SNX7,HBG2,ATP5IF1,PODXL2,RHOQ,GSTM4,SDC3,STEAP1,HERPUD1,RIPOR2,PLAGL1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,FNBP1L,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,KAZN,PPFIBP1,REEP1,FABP6,ACVR2A,FHIT,PROS1,ALG10B,ANTXR2,PTPN6,MVD,C3orf52,CD40,CENPV,BCL11A,ARMC4,TRIM34,KPNA3,EIF4EBP1,RBPMS2,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,IGF2BP2,COL4A5,FAM117B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,IPCEF1,TESPA1,USP2,KDM5B,SYBU,ASAP3,CCDC184,PEAK1,GALNT14,TLR6,LRAT,CTIF,SUGT1,ICA1,EDA,RND3,ACER2,CTSV,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,AASS,PRSS12,DNAJC3,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,PCDH7,EPDR1,BAG3,TGFBR3,FBXO32,PMAIP1,DNAH6,PPFIA2,RAB26,ZBED9,MEIS2,SMAD9,GJB2,TGFA,CAP2,WLS,HACD1,ELMOD1,MSRB3,F12,CA13,ALDOA,ARHGAP28,CRYL1,LPP,MEF2C,CARS,LATS2,CYP2J2,SLK,SLC36A4,GRPEL2,RSL24D1,BNIP1,BACE2,PRELID2,ST8SIA1,NCAM1,STXBP1,AGL,FMNL2,RPS23,HMGCR,FADS1,BDNF,ENAM,SLC37A1,PNP,MYO10,MGST3,STAT4,CALCRL,RYR2,PLS1,TAF4B,MBNL2,CPEB1,DHX32,BEX4,SH3GL2,FBXO27,NUDT10,DNM3,TMSB15A,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,LCP2,NRXN1,COLEC10,CDS1,TXNRD3,GPR15,EPB41L3,EEF1AKMT2,KMO,CNKSR3,DACT1,COL25A1,RTKN2,PJA1,RAB27B,SYNGR3,JAKMIP3,ARL4D,PERP,DOCK8,SCN3A,SSH3,GARS,FZD4,NPM3,PXYLP1,RAB38,TTC28,FGFR1,METAP1D,IRS2,GYPC,PEMT,WWTR1,INPP4B,PAM,ALG11,P4HA1,RCN3,HOXB9,SERINC5,FARP1,IPO5,P2RY1,PKN1,COL27A1,NEO1,MCF2L,GAS2L3,MORN2,MYO6,FES,ULBP1,LCA5,CLYBL,RAPGEF2,ELOVL3,RACK1,SNTB1,PTPRC,GALNT3,TRIB3,ID3,AKT3,XBP1,OSBPL5,HK1,DOCK6,BTRC,TPT1,NBPF4,NMNAT3,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,FKBP9,KCNN2,KCNAB1,HPS1,MARVELD2,COL19A1,TLN2,TLR4,NEB,CD55,GCNT2,SLC3A2,ABCC4,GDPD1,PLEKHA1,BATF,PLEKHB1,MAP2,GNB4,P4HA2,CCDC146,TNFRSF1A,PIK3C2B,CHMP4C,PRKAA2,RGS16,CHCHD7,UBASH3B,SETBP1,MLC1,PGAP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,GATA2,BCHE,ABCA5,PDE10A,BNIP3,FBXL2,SLCO4C1,FGFR4,CHSY3,PAK1,MID2,RNF170,SLC27A2,HOMER2,SPATA13,PPFIA4,PDE8A,LDHD,MAPKAPK2,ATPAF2,CSF1,HEYL,MFSD2A,PANK3,TESC,SFN,MME,PRKN,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,FAM198B,LPIN3,SEZ6L2,PCLO,CTNNA2,CYP26A1,FAM131B,RIDA,SLC22A17,ZDHHC6,MYO3B,CLVS2,CTH,GLI1,EVA1A,TMEM67,EVL,TUBA1A,UROS,NOP53,GSTO1,RARRES2,FRK,JAM3,ETNPPL,SMAD3,RANBP2,GBP1,ABI3,ITGA2,SEPT5,MAN2B2,COL9A3,LPAR2,IL32,GRB14,RUSC2,NLRP14,BLVRB,APBB1,SELL,GABRG2,HBE1,SFXN3,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,MOB1B,PPP1R3D,NUAK2,LITAF,FNDC3A,MAP10,FMO4,DLG2,MYRF,RPL4,TBC1D4,FILIP1,PPP4R4,DUSP8,ATP8A1,PPFIBP2,ENAH,RAC3,AARS,STK24,NCS1,MOK,SLC22A18,CHRDL1,GSTM3,SP140,PACSIN1,RCAN3,EML6,DCDC1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,DESI1,TNS1,SLC25A28,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,SFXN1,NCKAP1L,ENTPD7,CCDC181,RASGRF2,PLK2,B3GALT2,SPART,ZBED8,LZTS1,INPPL1,ALOX5AP,EHHADH,GABRB2,SCN8A,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,ADSSL1,DYNC1I1,NIPSNAP3B,CHD5,MYORG,RPL13A,MECOM,MCOLN2,GBGT1,NAV1,PIK3AP1,MSMO1,PRELID1,RUNDC3B,MPDZ,RIMS2,RNF152,EPB41L5,QSOX1,PLEKHA8,COL4A4,COLGALT2,RABAC1,PLCB1,FAM162A,VPS37D,PMEPA1,PKN3,IQSEC2,AMPD1,ACSM3,FRMPD3,EPHA3,PLA2G4A,PCSK1N,AMOTL1,RASAL2,ELOVL4,RNF144A,CHUK,SPATS2L,NUDT12,TBC1D30,STARD4,NBEA,SCRN1,DAB2IP,MARCKS,SERPINH1,PDK1,TMEM43,SFXN4,PRKCQ,TBC1D16,ZNF396,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,MAPK10,CTTNBP2,NR3C2,DENND5B,RPS20,WASF3,MXI1,ANKRD13D,GLIPR1L1,CLBA1,ATP9A,ARL2,RGS7,SELENOP,SLC35G2,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,PRKG2,PHYKPL,FIG4,YBX3,SEPT3,SPRY2,PFKFB4,SYNPO2,ARAP2,HYKK,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,TUFT1,PGM2L1,MYOM2,B4GALT7,OCLN,ATP1A3,NUDT17,EXPH5,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,ABAT,CACNB4,DNER,ABHD4,CEP85L,QPRT,FKBP11,ARHGEF10L,RTN1,TUBB4A,CYP51A1,LRRC6,GRHL1,AKAP7,SLC10A7,HRK,SLC2A12,EPHB6,PTPRE,FANK1,GALNT18,SLIT2,RASGRP1,PRKACB,ATL1,CAPN5,ROR1,SERGEF,GRK3,EML1,AK1,C8orf88,APBA2,SLC9B1,UST,FN1,SEC24D,RIMKLA,ELOVL7,CYP4V2,ATP6V1E2,GALNT13,PHGDH,DDIT4,CA2,RPS11,NCEH1,MORN4,NOS3,IL17RD,MSTN,SH2D2A,PARD3B,EDEM3,WWC1,DUSP9,GALNT17,PRDM1,LHPP,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,DIRC2,CREB3L2,EML5,NEK10,IL15,PLEKHA5,TDRKH,LACC1,DOCK2,UBTD2,COL22A1,SETDB2,UNC13B,RPS6KL1,MAP7,STEAP3,GULP1,MDH1B,MET,POU2F2,WWC2,HSPA2,GCA,PHLDB2,FER,TES,SYNJ2BP,DOCK5,TTLL7,WARS,TPK1,LMLN,BACH2,SOHLH2,CYP2U1,PSPH,TNIK,PRSS16,CLGN,REL,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,CHN2,GTSF1,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,NR4A1,CYTH3,OGDHL,MARS,PHACTR2,AGAP2,ARHGAP32,ZFPM2,MAP1B,GPR37,MYADM,GCSAM,NACC2,MAP2K6,PRCP,SLC7A5,KIAA0513,KIF21A,MMP16,MAP3K20,SNPH,STOM |
| 1.262e-07 | -15.89 | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | 6194 | 703 | 17385 | 1698 |
ARHGAP26,THOC5,GRIK2,AASS,CNTNAP3,RECK,NPM1,DOCK3,KIAA1217,SNX9,EYA4,SKI,EPDR1,BAG3,FBXO32,TGFBR3,IKZF5,DNAH6,TMEM37,COG3,TSHR,DCC,TGFA,CAP2,LRRK2,NFIA,MSRB3,MFSD6,INTS6,CA13,SLC7A1,ATP7B,ALDOA,BDH2,ARHGAP28,ZBTB20,TMOD2,TPM1,DNHD1,TMEFF2,CYP2J2,TJP1,FOXG1,BBS9,GRPEL2,SYCP2,FRY,BACE2,CACNB2,FLRT3,ZIC5,SRGAP1,TOX,LMAN2,FAM84B,ALPK1,LOXL4,FIGN,MOXD1,JAM2,AGL,GLIS1,STXBP1,GFRA1,CHRM3,ZNF385A,HMGCR,BDNF,SPATA6,ARID5B,PLS1,TAF4B,OR11H4,SPATA7,DHX32,CACHD1,TEX15,TMCO3,SH3GL2,QPCTL,EMILIN2,HOXD13,CDH2,CSRP2,BTC,NUDT10,ZNF516,MYO1B,LRRCC1,BEGAIN,ADD2,NRXN1,CDS1,EPB41L3,TLR3,GPRIN1,COL25A1,CNKSR3,RTKN2,ZNF365,DNAH5,MYT1,KCNB2,PERP,SCN3A,DOCK8,FZD1,C3orf67,SSH3,MYLK3,COL6A2,GAPDH,ADM2,FZD4,TRAM1L1,ADCY1,RAB38,DSP,ASPH,FGFR1,MAGI3,IRS2,ARHGAP21,IQCH,PDLIM3,GPR160,LAMB1,INPP4B,PLEKHG1,P4HA1,RCN3,DBP,CGB2,CCDC148,FARP1,ANKRD13B,WDR17,ROBO2,CKAP2,CD276,IPO5,NKAIN2,CREB5,KCNC4,NEO1,MYO6,MED12L,FES,TRPM4,MN1,MCF2L2,RAPGEF2,ELOVL3,RASA3,GALNT3,PTPRC,TRIB3,NSD1,PCDHB7,AKT3,GNAO1,OSBPL5,NEK11,CMPK2,DCBLD1,CRISPLD1,PHC1,PHACTR3,TRIM2,CACNG3,SYT12,FHDC1,LMCD1,LILRB1,NRN1,MGAT5B,ITPR2,NOVA1,FSTL5,CCNJ,PLS3,FKBP9,TM9SF2,KCNAB1,HPS1,TMEM143,JAKMIP2,TLN2,DBN1,ITGB7,MARK1,ATF4,ABCC4,COL4A3,ANK2,CR2,TTC22,PLEKHA1,SESN1,CRYBG3,TSKU,SPNS1,TRIM9,INHBC,INSIG1,KLF12,MAP2,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,CHMP4C,LONRF1,PRKAA2,RUNX2,STXBP5L,SETBP1,ZNF215,PFN2,IL18R1,PGAP1,HSPA12B,NUMBL,GALNT1,KIAA1958,IGF1R,SEMA4F,BCHE,SAMD11,LRP6,BNIP3,SLCO4C1,FAR2,PAK1,FGFR4,DPYSL5,CHSY3,RNF170,EFNA3,GPSM1,TMTC4,MAFB,SLITRK5,SDK1,BAIAP2,NEGR1,NAP1L5,MAPKAPK2,PLD1,SEMA3A,PANK3,TESC,MME,ID1,CFH,LPCAT2,XYLT1,RHPN2,ZNF83,OR51B4,LPIN3,SEZ6L2,KIF21B,RADIL,PPP1R9A,CBLN1,CYP26A1,TBC1D19,FAM131B,IDI1,TACC2,ZDHHC6,LHX6,MYO3B,BCL6,ZDHHC23,MYH15,HRASLS,INTU,EVL,TDRD3,PRDM13,ACO1,RNF125,RARRES2,FRK,IFT81,RANBP2,NRG3,PTPRJ,GBP1,ITGA2,PTPRS,HGF,MBOAT2,MAN2B2,PCDH18,BMPR2,KLHL13,GRB14,RUSC2,APBB1,GABRG2,USP30,PPP2R3A,SLC35F1,MAP1A,TSC22D1,SGK1,SH3PXD2B,KLF9,ESD,SLC45A3,KIAA1211,CES3,DUSP1,PALLD,EXOG,SMPDL3B,MKX,EBF1,CD37,DOCK7,FAT4,FBN1,ZNF214,SH3BGRL2,DLG2,RPL4,PAX9,TBC1D4,KIF1B,CACNA2D1,ZNF235,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,SIDT1,TTC39B,TCP11L2,LGR4,ATP8A1,LDLR,PPFIBP2,ADAMTS6,DACH2,AARS,HECTD2,SLC9A7,TRPS1,CFHR1,SLC22A18,SERINC2,KCNS3,CHRDL1,ATRNL1,RCAN3,THSD1,GLDC,GDAP1,WISP3,KLHL3,NR6A1,FAM84A,ALDH1L2,TNS1,ACVR2B,GPC6,SFXN1,SH3RF1,NCKAP1L,ENPP6,RASGRF2,BMP1,DSEL,MAPK13,UNC5B,NRP1,LZTS1,SPOCK3,CELSR1,EHHADH,ALOX5AP,ZHX3,TBC1D1,ST6GAL1,GABRB2,DHCR24,OPHN1,MRPL22,GTF2IRD1,SLC1A3,ADSSL1,DYNC1I1,TNFRSF19,RPL13A,MECOM,ABLIM1,GBGT1,NAV1,SLC7A11,NOVA2,PDZD7,RUNDC3B,PRKG1,CPXM2,GRIP1,TSPAN12,RIMS2,IGSF3,EPB41L5,QSOX1,RPL26,TBC1D8B,SLC36A1,PLEKHA8,COL4A4,PACSIN3,KIAA1324L,TTYH2,PEX5L,NPC2,CDC42BPA,PLCB1,FAM162A,ZNF558,TMEM74,MMP15,PLEKHH2,PKN3,C1orf21,LRRIQ3,MPP2,IQSEC2,SLFN5,ACSM3,EPHA3,TCTN2,ELOVL4,RASAL2,ST14,GPR65,CCDC110,MSR1,CHUK,COL14A1,NUDT12,ZFYVE9,TIAM2,SPEG,NELL2,ASNS,ZNF438,SCRN1,MARCKS,SERPINH1,ATP6AP1L,TRDMT1,PREX1,NLGN4X,SATB2,ATP1B1,TBC1D16,ZNF396,PRKCB,TDO2,CCNA1,GRB10,KLF5,BMPR1A,HS3ST3B1,CTTNBP2,STON2,MID1,COBL,HACE1,WASF3,MYO1D,ANKRD13D,GLIPR1L1,EPS8,CCNJL,HERC5,GDPD5,INPP1,PHLDA2,RASSF8,LRRC55,GPR155,SGK3,FIG4,SPRY2,SMPDL3A,B4GALT6,PFKFB4,TMC7,SLC40A1,ALDH2,ARAP2,SYNPO2,AGPAT4,RPL21,GUCY1A2,SKAP1,ZIC1,FGR,TERT,PLXDC2,MYOM2,TNFRSF17,LARP1,DDIT3,SLC43A1,ATP1A3,NUDT17,EXPH5,MPZL3,MVK,UGT8,KIF5A,HEBP1,UGDH,PTPN21,C20orf194,SLC2A13,IKZF2,KREMEN1,HMCN1,QPRT,EPCAM,ARHGEF10L,SIPA1L2,PPM1E,LRRC6,ANKFN1,POF1B,CNNM2,SLC2A12,CTTN,MYRIP,PRKACB,PDGFRB,CYP1B1,ATL1,GPM6A,CAPN5,JPH1,YAP1,TMEM47,TMEM132B,GSN,GPRC5B,HPSE,ITGBL1,FAM114A2,NCOA7,OXTR,PPARGC1A,APBA2,MAGI2,FRMD5,PCSK5,GPT2,MOCOS,ZNF395,FN1,SEC24D,FBXO4,RIMKLA,CYP4V2,LAMC3,ATP6V1E2,SCD,GALNT13,CHSY1,SPINK5,PHGDH,DDIT4,PCDHB14,CA2,SLC30A4,EEF2,RPS11,LIMCH1,LRP3,CAND2,CEBPD,SNX7,NOS3,PCDH10,SLITRK2,GSTM4,PARD3B,PRDM1,B4GALNT3,STEAP1,HERPUD1,PLAGL1,KIAA0355,CSAG1,HK2,RAI14,SH3BP4,PTPRN2,DISP2,DIRC2,CREB3L2,DMXL2,ZSWIM5,SORBS1,CELSR3,PLEKHA5,HECW2,MORC4,COL18A1,COBLL1,TDRKH,CANX,PIBF1,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,UNC13B,SETDB2,CDC14B,RPS6KL1,KAZN,PPFIBP1,C12orf60,ZNF521,ACVR2A,STEAP3,PROS1,POU2F2,MET,HSPA2,SEMA6C,DPP10,PHLDB2,FER,GCA,PTPRU,AMIGO1,TTLL7,C1orf174,ZNF569,WARS,ARMC4,LMLN,BACH2,RGS10,SOHLH2,DISP1,MAST1,ENO2,TSPAN15,CLGN,LRP4,CLSTN2,COL4A5,CUEDC2,BMP6,FSD1,KCNJ4,DSG2,KIAA0319,CCDC122,AFAP1L2,DHRS12,IQGAP3,RBMS2,CARD6,CRIM1,NR4A1,CYTH3,SYBU,GRID1,MARS,PHACTR2,TLR6,LEPR,MAP1B,RERE,DPY19L2,ADAMTS17,TIFA,MYADM,NACC2,RND3,ACER2,PRCP,SLC7A5,KIF21A,GEM,NPHP1,MMP16,ABCG1,SNPH |
| 1.290e-07 | -15.86 | PH_DOMAIN | prosite domains | PS50003 | 246 | 54 | 12060 | 1278 |
ARHGAP26,FARP1,DNM3,ARHGEF11,GRB14,PLEKHA5,ARHGAP22,OPHN1,PSD3,TIAM2,RALGPS2,MCF2L,AFAP1L2,DAB2IP,RTKN2,CADPS2,IPCEF1,GAB2,PHLDB2,VAV3,ARAP2,SH3BP2,ARHGEF28,SKAP2,MYO10,PLEKHA8,MCF2L2,CYTH3,ASAP3,PREX1,SPATA13,RASA3,OBSCN,FERMT2,AGAP2,PLEKHA1,CDC42BPA,SNTB1,SKAP1,GRK3,PLEKHB1,ARHGEF26,TBC1D2,IRS2,ARHGAP21,PLEKHH2,AKT3,RASGRF2,OSBPL5,PLEKHG1,GRB10,OSBPL6,KIF1B,DOCK9 |
| 1.306e-07 | -15.85 | ENK_UV_RESPONSE_EPIDERMIS_DN | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_DN | 490 | 85 | 17377 | 1707 |
ACSL1,DUSP8,TRIM16,ST14,HEBP1,PTPN21,PLXNA2,GATA3,ASS1,SLCO3A1,F3,TRPS1,NELL2,TGFBR3,RPS6KA2,TACC2,SLC22A18,PROS1,EPHB6,GATM,SNAI2,GAB2,IGFBP3,CD55,TUBA1A,ABCC4,SKAP2,PNRC1,TGFA,YAP1,ATF3,INTS6,EML1,GNAI1,ISG20,BCL11A,IRS2,GSN,HLF,PRKCB,ENTPD7,ITGA2,BDH2,HPGD,DBP,LPP,BCL11B,SLC6A9,LGALS3,CYP2J2,DHCR24,GAS6,PHGDH,SPINK5,SATB1,NEO1,FRY,BCHE,PRKCD,OPN3,GAN,MYO6,STXBP1,SPRY2,ZFP36L2,ATP2B1,VAV3,ALDH2,PNP,MGST3,FOXN3,FHL2,MGMT,MAPKAPK2,ID3,DDAH1,PLAGL1,PELI2,MATN2,C1orf21,SLC7A5,RAI14,HK2,PLD1,PKIA |
| 1.311e-07 | -15.85 | FORTSCHEGGER_PHF8_TARGETS_UP | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_UP | 243 | 51 | 17377 | 1707 |
GPT2,NEK10,STOX2,ID1,GPR180,ENAH,SCD,RASD1,CHAC1,PHGDH,BMP6,SLC19A2,DDIT4,MOK,RNF141,ASNS,IGF1R,SLC7A11,MCF2L,STC2,MAP7,STEAP3,TSPAN13,KLF9,PDE4D,PCK2,VAV3,ATF4,SESN2,NR4A1,ALDH1L2,VLDLR,TMTC4,ACVR2B,C9orf116,HERPUD1,CENPV,PYCR1,DDAH1,IQCK,PTPRJ,RIMKLB,MAP2,NCOA7,INHBE,ARHGAP28,GRB10,TBC1D4,FNBP1L,DCBLD1,HEY1 |
| 1.319e-07 | -15.84 | PEREZ_TP53_TARGETS | MSigDB lists | PEREZ_TP53_TARGETS | 1037 | 153 | 17377 | 1707 |
ACVR1,TRIM2,SIDT1,FGF13,CNTNAP3,GATA3,FAM102B,CEBPA,CHAC1,KIAA1217,ABHD4,ABHD6,SIPA1L2,EOMES,ZFYVE28,AKAP7,CPE,RAPGEF5,IL1RAP,GLDC,KCNIP3,GCNT2,EML6,SMAD9,KLHL3,DNAJC6,JPH1,ELMOD1,TNS1,EML1,AK1,WIPF3,TECPR2,AHNAK2,MAPK13,UNC5B,VASH2,LZTS1,FRMD5,GPT2,STOX2,EHHADH,CHCHD7,BVES,ZCCHC24,ZNF215,ZIC2,ADSSL1,MLC1,PGAP1,MCOLN2,IGF1R,EEF2,FRY,KIAA1671,ZNF440,GATA2,CACNB2,PDE10A,ADCY6,TOX,MOXD1,ZNF385A,BDNF,MYO10,COL4A4,GPSM1,TTYH2,OBSCN,MAFB,BAIAP2,C11orf45,ATPAF2,VPS37D,FCHO2,EMILIN2,FBRSL1,DISP2,DOCK9,CREB3L2,AMOTL1,GALNT12,ABHD13,COL18A1,FAM198B,LACC1,COL22A1,EPB41L3,KAZN,DACT1,CNKSR3,LHX6,ALDH1L1,REEP1,DAB2IP,MYT1,KIAA1549,GATM,DOCK8,FZD1,IGFBP3,INTU,ADCY1,WNT11,FRK,SMAD3,PTPRJ,CCNA1,DUSP19,HPGD,FAM149A,HS3ST3B1,DISP1,LIFR,COL9A3,C2orf88,MXI1,ENO2,BACE1,BIK,GDPD5,KCNC4,ARHGAP44,COL27A1,LRRN1,MCF2L,GPR155,GHR,TRIM3,MARCH3,CERS4,MYO6,SMAD6,C15orf41,KIAA1211,CES3,MOB1B,MN1,MSX1,ELOVL3,CRIP2,ILDR2,SMPDL3B,HEG1,GPR37,ZFP62,DDAH1,MFSD9,MCC,TUFT1,CMPK2,KIF1B,ABCG1 |
| 1.335e-07 | -15.83 | transitional_cell_carcinoma | COSMIC cancer mutations | transitional_cell_carcinoma | 6196 | 703 | 17385 | 1698 |
ARHGAP26,THOC5,GRIK2,AASS,CNTNAP3,RECK,NPM1,DOCK3,KIAA1217,SNX9,EYA4,SKI,EPDR1,BAG3,FBXO32,TGFBR3,IKZF5,DNAH6,TMEM37,COG3,TSHR,DCC,TGFA,CAP2,LRRK2,NFIA,MSRB3,MFSD6,INTS6,CA13,SLC7A1,ATP7B,ALDOA,BDH2,ARHGAP28,ZBTB20,TMOD2,TPM1,DNHD1,TMEFF2,CYP2J2,TJP1,FOXG1,BBS9,GRPEL2,SYCP2,FRY,BACE2,CACNB2,FLRT3,ZIC5,SRGAP1,TOX,LMAN2,FAM84B,ALPK1,LOXL4,FIGN,MOXD1,JAM2,AGL,GLIS1,STXBP1,GFRA1,CHRM3,ZNF385A,HMGCR,BDNF,SPATA6,ARID5B,PLS1,TAF4B,OR11H4,SPATA7,DHX32,CACHD1,TEX15,TMCO3,SH3GL2,QPCTL,EMILIN2,HOXD13,CDH2,CSRP2,BTC,NUDT10,ZNF516,MYO1B,LRRCC1,BEGAIN,ADD2,NRXN1,CDS1,EPB41L3,TLR3,GPRIN1,COL25A1,CNKSR3,RTKN2,ZNF365,DNAH5,MYT1,KCNB2,PERP,SCN3A,DOCK8,FZD1,C3orf67,SSH3,MYLK3,COL6A2,GAPDH,ADM2,FZD4,TRAM1L1,ADCY1,RAB38,DSP,ASPH,FGFR1,MAGI3,IRS2,ARHGAP21,IQCH,PDLIM3,GPR160,LAMB1,INPP4B,PLEKHG1,P4HA1,RCN3,DBP,CGB2,CCDC148,FARP1,ANKRD13B,WDR17,ROBO2,CKAP2,CD276,IPO5,NKAIN2,CREB5,KCNC4,NEO1,MYO6,MED12L,FES,TRPM4,MN1,MCF2L2,RAPGEF2,ELOVL3,RASA3,GALNT3,PTPRC,TRIB3,NSD1,PCDHB7,AKT3,GNAO1,OSBPL5,NEK11,CMPK2,DCBLD1,CRISPLD1,PHC1,PHACTR3,TRIM2,CACNG3,SYT12,FHDC1,LMCD1,LILRB1,NRN1,MGAT5B,ITPR2,NOVA1,FSTL5,CCNJ,PLS3,FKBP9,TM9SF2,KCNAB1,HPS1,TMEM143,JAKMIP2,TLN2,DBN1,ITGB7,MARK1,ATF4,ABCC4,COL4A3,ANK2,CR2,TTC22,PLEKHA1,SESN1,CRYBG3,TSKU,SPNS1,TRIM9,INHBC,INSIG1,KLF12,MAP2,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,CHMP4C,LONRF1,PRKAA2,RUNX2,STXBP5L,SETBP1,ZNF215,PFN2,IL18R1,PGAP1,HSPA12B,NUMBL,GALNT1,KIAA1958,IGF1R,SEMA4F,BCHE,SAMD11,LRP6,BNIP3,SLCO4C1,FAR2,PAK1,FGFR4,DPYSL5,CHSY3,RNF170,EFNA3,GPSM1,TMTC4,MAFB,SLITRK5,SDK1,BAIAP2,NEGR1,NAP1L5,MAPKAPK2,PLD1,SEMA3A,PANK3,TESC,MME,ID1,CFH,LPCAT2,XYLT1,RHPN2,ZNF83,OR51B4,LPIN3,SEZ6L2,KIF21B,RADIL,PPP1R9A,CBLN1,CYP26A1,TBC1D19,FAM131B,IDI1,TACC2,ZDHHC6,LHX6,MYO3B,BCL6,ZDHHC23,MYH15,HRASLS,INTU,EVL,TDRD3,PRDM13,ACO1,RNF125,RARRES2,FRK,IFT81,RANBP2,NRG3,PTPRJ,GBP1,ITGA2,PTPRS,HGF,MBOAT2,MAN2B2,PCDH18,BMPR2,KLHL13,GRB14,RUSC2,APBB1,GABRG2,USP30,PPP2R3A,SLC35F1,MAP1A,TSC22D1,SGK1,SH3PXD2B,KLF9,ESD,SLC45A3,KIAA1211,CES3,DUSP1,PALLD,EXOG,SMPDL3B,MKX,EBF1,CD37,DOCK7,FAT4,FBN1,ZNF214,SH3BGRL2,DLG2,RPL4,PAX9,TBC1D4,KIF1B,CACNA2D1,ZNF235,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,SIDT1,TTC39B,TCP11L2,LGR4,ATP8A1,LDLR,PPFIBP2,ADAMTS6,DACH2,AARS,HECTD2,SLC9A7,TRPS1,CFHR1,SLC22A18,SERINC2,KCNS3,CHRDL1,ATRNL1,RCAN3,THSD1,GLDC,GDAP1,WISP3,KLHL3,NR6A1,FAM84A,ALDH1L2,TNS1,ACVR2B,GPC6,SFXN1,SH3RF1,NCKAP1L,ENPP6,RASGRF2,BMP1,DSEL,MAPK13,UNC5B,NRP1,LZTS1,SPOCK3,CELSR1,EHHADH,ALOX5AP,ZHX3,TBC1D1,ST6GAL1,GABRB2,DHCR24,OPHN1,MRPL22,GTF2IRD1,SLC1A3,ADSSL1,DYNC1I1,TNFRSF19,RPL13A,MECOM,ABLIM1,GBGT1,NAV1,SLC7A11,NOVA2,PDZD7,RUNDC3B,PRKG1,CPXM2,GRIP1,TSPAN12,RIMS2,IGSF3,EPB41L5,QSOX1,RPL26,TBC1D8B,SLC36A1,PLEKHA8,COL4A4,PACSIN3,KIAA1324L,TTYH2,PEX5L,NPC2,CDC42BPA,PLCB1,FAM162A,ZNF558,TMEM74,MMP15,PLEKHH2,PKN3,C1orf21,LRRIQ3,MPP2,IQSEC2,SLFN5,ACSM3,EPHA3,TCTN2,ELOVL4,RASAL2,ST14,GPR65,CCDC110,MSR1,CHUK,COL14A1,NUDT12,ZFYVE9,TIAM2,SPEG,NELL2,ASNS,ZNF438,SCRN1,MARCKS,SERPINH1,ATP6AP1L,TRDMT1,PREX1,NLGN4X,SATB2,ATP1B1,TBC1D16,ZNF396,PRKCB,TDO2,CCNA1,GRB10,KLF5,BMPR1A,HS3ST3B1,CTTNBP2,STON2,MID1,COBL,HACE1,WASF3,MYO1D,ANKRD13D,GLIPR1L1,EPS8,CCNJL,HERC5,GDPD5,INPP1,PHLDA2,RASSF8,LRRC55,GPR155,SGK3,FIG4,SPRY2,SMPDL3A,B4GALT6,PFKFB4,TMC7,SLC40A1,ALDH2,ARAP2,SYNPO2,AGPAT4,RPL21,GUCY1A2,SKAP1,ZIC1,FGR,TERT,PLXDC2,MYOM2,TNFRSF17,LARP1,DDIT3,SLC43A1,ATP1A3,NUDT17,EXPH5,MPZL3,MVK,UGT8,KIF5A,HEBP1,UGDH,PTPN21,C20orf194,SLC2A13,IKZF2,KREMEN1,HMCN1,QPRT,EPCAM,ARHGEF10L,SIPA1L2,PPM1E,LRRC6,ANKFN1,POF1B,CNNM2,SLC2A12,CTTN,MYRIP,PRKACB,PDGFRB,CYP1B1,ATL1,GPM6A,CAPN5,JPH1,YAP1,TMEM47,TMEM132B,GSN,GPRC5B,HPSE,ITGBL1,FAM114A2,NCOA7,OXTR,PPARGC1A,APBA2,MAGI2,FRMD5,PCSK5,GPT2,MOCOS,ZNF395,FN1,SEC24D,FBXO4,RIMKLA,CYP4V2,LAMC3,ATP6V1E2,SCD,GALNT13,CHSY1,SPINK5,PHGDH,DDIT4,PCDHB14,CA2,SLC30A4,EEF2,RPS11,LIMCH1,LRP3,CAND2,CEBPD,SNX7,NOS3,PCDH10,SLITRK2,GSTM4,PARD3B,PRDM1,B4GALNT3,STEAP1,HERPUD1,PLAGL1,KIAA0355,CSAG1,HK2,RAI14,SH3BP4,PTPRN2,DISP2,DIRC2,CREB3L2,DMXL2,ZSWIM5,SORBS1,CELSR3,PLEKHA5,HECW2,MORC4,COL18A1,COBLL1,TDRKH,CANX,PIBF1,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,UNC13B,SETDB2,CDC14B,RPS6KL1,KAZN,PPFIBP1,C12orf60,ZNF521,ACVR2A,STEAP3,PROS1,POU2F2,MET,HSPA2,SEMA6C,DPP10,PHLDB2,FER,GCA,PTPRU,AMIGO1,TTLL7,C1orf174,ZNF569,WARS,ARMC4,LMLN,BACH2,RGS10,SOHLH2,DISP1,MAST1,ENO2,TSPAN15,CLGN,LRP4,CLSTN2,COL4A5,CUEDC2,BMP6,FSD1,KCNJ4,DSG2,KIAA0319,CCDC122,AFAP1L2,DHRS12,IQGAP3,RBMS2,CARD6,CRIM1,NR4A1,CYTH3,SYBU,GRID1,MARS,PHACTR2,TLR6,LEPR,MAP1B,RERE,DPY19L2,ADAMTS17,TIFA,MYADM,NACC2,RND3,ACER2,PRCP,SLC7A5,KIF21A,GEM,NPHP1,MMP16,ABCG1,SNPH |
| 1.347e-07 | -15.82 | HAN_SATB1_TARGETS_DN | MSigDB lists | HAN_SATB1_TARGETS_DN | 415 | 75 | 17377 | 1707 |
MCOLN3,F3,CYP51A1,EPB41L3,NELL2,RPS6KA2,ALDOC,CHRDL1,GSTM3,PDE4D,SERPINH1,SYNGR3,PTPRE,HSPA2,COL6A2,FZD4,SHANK2,DNAJC6,TNS1,CD40,ASPH,GNAI1,ISG20,LAMB1,P4HA1,KLF5,TNFSF15,TPM1,PCSK5,DENND5B,WASF3,MYO1D,ENO2,IL32,CELSR1,ZCCHC24,STXBP6,DHCR24,COL4A5,SFXN3,IL18R1,NEDD4,DDIT4,NEO1,EFEMP1,GALNT1,HMGCS1,SLC7A11,MSMO1,BCHE,PDE10A,LIMCH1,TOX,BNIP3,STXBP1,RIMS2,HMGCR,DUSP1,BDNF,VLDLR,AK4,PDE8A,RABAC1,C4orf19,DDAH1,NACC2,PLOD2,RND3,PELI2,SLC2A6,XBP1,MATN2,INHBE,SQLE,SFN |
| 1.360e-07 | -15.81 | negative regulation of signaling | biological process | GO:0023057 | 1382 | 190 | 17256 | 1658 |
ACVR1,DUSP8,LGR4,GRIK2,GATA3,NDRG2,CHAC1,ABHD6,KREMEN1,EYA4,SKI,TGFBR3,ZFYVE28,CHRDL1,CTTN,EPHB6,PTPRE,TLR4,ENO1,SLIT2,PRKACB,PDGFRB,NKX2-1,SESN2,ACVR1C,LRRK2,DEPTOR,YAP1,ROR1,PLEKHA1,SESN1,TSKU,GNAI1,ENPP1,INSIG1,SH3RF1,PLK2,INPP5F,SPRY4,DLX2,NRP1,UNC5B,PPARGC1A,SPART,MAGI2,MLLT3,PRKAA2,TYRO3,RGS16,LATS2,RUNX2,LGALS3,STXBP5L,ITGA6,UBASH3B,RASL11B,MECOM,DDIT4,IGF1R,BCHE,GATA2,MYC,FLRT3,C1QL4,PRELID1,SREBF1,LRP6,STXBP1,BARX1,GPR161,ZNF385A,NOS3,RNF152,HMGCR,PTCH2,FGFR4,MSTN,DUSP9,WWC1,STRADB,SHISA2,PRDM1,HERPUD1,RIPOR2,SH3GL2,PMEPA1,HEYL,SH3BP4,EGFL7,CDH2,EPHA3,PRKN,NBL1,BTC,RASAL2,RGS20,NTRK3,TMEM170B,DDR1,PIBF1,PPP1R9A,CBLN1,CYP26A1,TLR3,CNKSR3,DACT1,MAGEA3,BCL6,DAB2IP,WWC2,MET,SNAI2,GLI1,CTH,IGFBP3,FZD1,PRAME,NOP53,PTPN6,SHANK2,PREX1,RNF125,NLGN4X,PRKCQ,WNT11,CBY1,GSTO1,ATF3,SYNJ2BP,FGFR1,SNCA,CAMK2N1,SMAD3,PTPRJ,PRKCB,GBP1,RBPMS2,WFS1,ASIC1,WWTR1,MAP3K21,RGS10,DUSP19,PTPRS,HGF,GRB10,HEY1,DYRK3,IGFBP6,C1QTNF3,PAK5,GRB14,LRP4,NOTUM,GAS6,EPHB1,RGS7,GDPD5,ARHGAP44,NEDD4,RAB11FIP5,RGS17,PRKCD,SGK3,YBX3,ERRFI1,SMAD6,SPRY2,DUSP1,GSTM2,LITAF,PRICKLE1,RASA3,RACK1,TLR6,SMPDL3B,DKK1,PTPRC,TRIB3,MYADM,TERT,FBN1,XBP1,MCC,PCGF2,BMP4,DDIT3,ATP2B4,BTRC,TPT1 |
| 1.377e-07 | -15.80 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_UP | 177 | 41 | 17377 | 1707 |
UST,FN1,IL15,GALNT12,STXBP6,HERC5,ADSSL1,DDX60L,HOPX,MCOLN2,EPCAM,ABLIM1,HMGCS1,ZNF521,TOX,SCN2A,RAB27B,GATM,DBN1,ITGB7,DNAJC6,CHRNA6,FERMT2,PRKAR2B,PALLD,TEX9,NEGR1,GNAI1,BATF3,ZNF711,TRIM9,ZNF93,CXCL10,GBP1,INPP4B,ADRB1,HPGD,HS3ST3B1,GEM,CMPK2,OSBPL6 |
| 1.399e-07 | -15.78 | positive regulation of cellular process | biological process | GO:0048522 | 5055 | 578 | 17256 | 1658 |
THOC5,GRIK2,DNAJC3,LSM11,NPM1,CTBP2,STAT5B,CEBPA,SNX9,EYA4,NOS1AP,SKI,TGFBR3,PMAIP1,RAP2A,TMED9,TSHR,POU3F3,NKX2-1,MEIS2,SMAD9,WLS,DSTN,TGFA,LRRK2,NFIA,FEZ1,PRKAR2B,FGF17,F12,WIPF3,ADRB1,BBC3,TMOD2,ERCC5,INPP5F,DIRAS1,TPM1,VASH2,MEF2C,SCN5A,LATS2,ITGA6,SLK,GPSM2,FOXG1,CHN1,APLF,FLRT3,LMAN2,TOX,CADPS2,ST8SIA1,GLIS1,STXBP1,ZNF385A,HMGCR,BDNF,PNP,STAT4,FHL2,FASN,RYR2,HIP1,CALCRL,SMARCD3,SNAP25,ARRDC4,TAF4B,SH3GL2,ADAMTS3,CDH17,INHBE,HOXD13,CDH2,TRPC3,SHTN1,BTC,DNM3,ZNF516,C4A,NRXN1,LCP2,TLR3,KMO,DACT1,RTKN2,RAB27B,ZNF365,PERP,DOCK8,FZD1,MYLK3,GAPDH,FZD4,PFKFB2,ADCY1,WNT11,PXYLP1,ASPH,FGFR1,IRS2,CXCL10,WFS1,PEMT,APELA,WWTR1,LAMB1,TNFSF15,DBP,HOXB9,C1QTNF3,EDA2R,ROBO2,CKAP2,PLAG1,FZD8,CD276,BIK,GAS6,P2RY1,CREB5,PKN1,EPHB1,ZNF219,TSPAN17,NEO1,LRRN1,PCBP4,MCF2L,BHLHA15,GHR,MYO6,ZFP36L2,FES,MED12L,PARP9,PDLIM7,TRPM4,VEGFC,RAPGEF2,GAREM1,RACK1,PTPRC,TRIB3,ID3,NSD1,AKT3,XBP1,BMP4,SHOX2,ATP2B4,FOXA1,BTRC,CACNG3,FGF13,TRIM16,SYT12,LMCD1,LILRB1,ASS1,RND2,RPS6KA2,TCAF2,EOMES,ITGB3,ETV1,TLR4,ENO1,CD55,ATF4,GCNT2,COL4A3,ANK2,NFE2L1,BATF,SESN1,DYRK1B,INHBC,INSIG1,ERN1,TNFRSF1A,DLX2,CACUL1,MLLT3,RRAGD,PRKAA2,LONRF1,TYRO3,RUNX2,LGALS3,STXBP5L,SORBS3,ZIC2,PFN2,IL18R1,SPIRE1,RNF180,NUMBL,ZBTB38,SEMA4F,IGF1R,GATA2,LRP6,ADCY6,BNIP3,PAK1,FGFR4,UNC5C,MID2,EFNA3,GPSM1,STRADB,MAFB,OBSCN,SLITRK5,PDE8A,BAIAP2,NEGR1,MAPKAPK2,CSF1,HEYL,SEMA3A,TESC,SIX2,SFN,PRKN,ID1,AVPI1,DOCK1,NTRK3,LPIN3,TNKS1BP1,PPP1R9A,CBLN1,SEMA6A,CTNNA2,BCL6,ADGRL1,ZNF488,SNAI2,GLI1,CTH,IGFBP3,INTU,EVL,NOP53,RNF125,VIM,GSTO1,RARRES2,SMAD3,RANBP2,NRG3,PTPRJ,RNF217,PTK7,ITGA2,HGF,CNTN1,HEY1,TENM1,NECAB2,BMPR2,GRB14,PAK5,APBB1,FOXP2,RASD2,GTF2F2,TFAP2A,SH3PXD2B,PCK2,SYK,SLC45A3,DUSP1,MOB1B,MICAL2,FOXN3,CRIP2,LITAF,PRICKLE1,MGMT,MAP10,DKK1,EBF1,DDAH1,DOCK7,MYRF,PAX9,ACVR1,LGR4,ATP8A1,LDLR,VAMP8,GATA3,PRKCA,RAC3,NCS1,STK24,TRPS1,FAM168A,CFHR1,PACSIN1,TBC1D8,NR6A1,ACVR1C,BNIP3L,MEF2B,ACVR2B,SAV1,ARHGEF26,AHRR,HLF,NCKAP1L,CCBE1,PLK2,RASGRF2,SERPINI1,SEMA3C,UNC5B,NRP1,EFNB2,ZHX3,PTPRD,SLC25A27,SLC1A3,TNFRSF10C,TNFRSF19,CHD5,MYORG,MECOM,PIK3AP1,MYC,PRELID1,SREBF1,GRIP1,PRR16,GPR161,RIMS2,RNF152,PTCH2,EPB41L5,RPL26,DISC1,VLDLR,PACSIN3,NSD2,PLCB1,FAM162A,PELI2,THBS4,MPP2,SMYD3,EPHA3,NBL1,AMOTL1,RNF144A,RHOD,GPR65,PLXNA2,MSR1,OTX1,CHUK,DDR1,TIAM2,ASNS,STARD4,SHF,DAB2IP,GAB2,SOX21,SHANK2,PREX1,PRKCQ,SATB2,ATF3,ATOH1,PYGO1,ATP1B1,SNCA,ZNF711,IKZF3,BEX3,PRKCB,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,MAPK10,COBL,MID1,WASF3,EPS8,ARL2,NDFIP2,TPD52L1,GDPD5,ADGRB2,NEDD4,GSAP,KDM7A,LRRC55,FIG4,DYNC2H1,YBX3,SMAD6,GFI1,SPRY2,PFKFB4,VAV3,SLC40A1,SYNPO2,SH3BP2,GSTM2,PXN,GUCY1A2,SKAP1,HOXA1,ZIC1,GPLD1,CEBPB,FGR,TERT,SVIL,GRIN2D,LRRK1,LARP1,DDIT3,EXPH5,ACSL1,JCHAIN,ABAT,IKZF2,GSDME,F3,EPCAM,ARHGEF10L,PPM1E,GRHL1,DLX6,TRPC1,HRK,EPHB6,PCOLCE2,CTTN,FANK1,MYRIP,IL1RAP,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,TNK2,GPM6A,SESN2,SKAP2,YAP1,ROR1,GSN,GPRC5B,HPSE,NCOA7,OXTR,TNFSF4,PPARGC1A,MAGI2,BCL11B,FN1,BVES,JDP2,FBXO4,CHSY1,DDIT4,EEF2,CA2,EBF4,INAVA,BARX1,CEBPD,CAND2,NOS3,RAX,ATP5IF1,RHOQ,SLITRK2,MSTN,SH2D2A,WWC1,DUSP9,PRDM1,HERPUD1,RIPOR2,PLAGL1,ADGRB3,SH3BP4,HK2,EGFL7,NKX2-8,FNBP1L,CREB3L2,CXCR5,NEK10,SORBS1,IL15,COL18A1,PIBF1,DOCK2,CD53,SCIN,UNC13B,CDC14B,ACVR2A,MET,POU2F2,HSPA2,ALG10B,PRAME,FER,PHLDB2,MVD,PTPN6,AMIGO1,CD40,DOCK5,CENPV,WARS,RBPMS2,EIF4EBP1,DUSP19,SOHLH2,DISP1,LIFR,TNIK,ARHGEF11,REL,LRP4,TNFSF13B,CLSTN2,SLX1B,OVOL2,BMP6,MCU,NKX6-1,CHN2,SCN1B,PRKCD,AFAP1L2,IQGAP3,RRAS2,TNFRSF11A,TESPA1,PNMA2,USP2,RAB3B,MSX1,KDM5B,HNF4G,ESRRG,NR4A1,SYBU,AGAP2,MARS,ZFPM2,TLR6,RERE,MAP1B,GPR37,MYADM,EDA,MPP7,NACC2,MAP2K6,ACER2,NPHP1,MAP3K20 |
| 1.415e-07 | -15.77 | PDZ | pfam domains | PF00595 | 128 | 33 | 17054 | 1666 |
FRMPD3,ARHGEF11,TJP1,APBA1,RADIL,PPP1R9A,PCLO,TIAM2,PDZD8,PDZD7,CNKSR3,LIN7A,GRIP1,MPDZ,MAST4,PDLIM7,SYNPO2,PTPN13,MPP1,RAPGEF2,PARD3B,SHANK2,SYNJ2BP,SNTB1,MAGI3,ARHGAP21,PDLIM3,MPP7,MPP2,DLG2,APBA2,MAGI2,MAST1 |
| 1.430e-07 | -15.76 | actin binding | molecular function | GO:0003779 | 411 | 74 | 17224 | 1680 |
PHACTR3,CGN,PRKN,SORBS1,TMSB15A,PSTPIP2,MYO1B,ADD2,COBLL1,ENAH,PPP1R9A,CTNNA2,PLS3,SCIN,EPB41L3,MYO3B,POF1B,MYH15,MARCKS,TLN2,MYRIP,NEB,DBN1,SSH3,EVL,KLHL3,CAP2,DSTN,KLHL4,LRRK2,TNS1,COTL1,GSN,WIPF3,GBP1,ALDOA,TMOD2,TPM1,COBL,WASF3,MYO1D,INPPL1,EPS8,OPHN1,ADSSL1,PFN2,SPIRE1,FHOD3,ABLIM1,MAP1A,EEF2,CACNB2,GAS2L3,SMTN,LIMCH1,MYO6,FMNL2,NOS3,MICAL2,SYNPO2,MYO10,HOMER2,HIP1,PHACTR2,PLS1,PALLD,SNTB1,MAP1B,PLEKHH2,GCSAM,SVIL,CLMN,MYOM2,SHTN1 |
| 1.436e-07 | -15.76 | circulatory system development | biological process | GO:0072359 | 825 | 125 | 17256 | 1658 |
AMOTL1,ACVR1,ID1,RECK,ARHGAP22,GATA3,PKP2,COL18A1,ADAMTS6,NTRK3,PRKCA,TYMP,TGFBR3,SETDB2,EOMES,KCNAB1,ITGB3,TBC1D32,DAB2IP,CPE,SLIT2,PDGFRB,SNAI2,CYP1B1,FZD1,MYLK3,CEMIP2,FZD4,ADM2,TMEM65,ANK2,FGF12,MEF2B,YAP1,WNT11,CBY1,ACVR2B,SAV1,DSP,JAM3,FGFR1,WARS,GJC1,SMAD3,ARMC4,POPDC3,HPSE,CCBE1,PTK7,APELA,PAM,HPGD,KLF5,SEMA3C,OXTR,BMPR1A,ATG5,UNC5B,NRP1,TPM1,VASH2,MEF2C,PCSK5,HEY1,EFNB2,SCN5A,BMPR2,FN1,BVES,FZD8,OVOL2,SLC12A6,EPHB1,ADGRG6,FHOD3,GATA2,FLRT3,DSG2,ACTA2,LRP6,TSPAN12,SH3PXD2B,LOXL4,DYNC2H1,ERRFI1,SMAD6,SYK,NOS3,FGFR4,B9D1,VEGFC,MICAL2,ATP5IF1,VAV3,MSX1,SH2D2A,NR4A1,RAPGEF2,DCHS1,FHL2,SMARCD3,RYR2,CALCRL,NSD2,PRICKLE1,SLITRK5,PRDM1,ZFPM2,HOXA1,LEPR,GPLD1,HEG1,ID3,FAT4,FBN1,PRCP,HEYL,XBP1,EGFL7,MYOM2,BMP4,DHCR7,SHOX2,CDH2,DDIT3 |
| 1.442e-07 | -15.75 | AAGCAAT,MIR-137 | MSigDB lists | AAGCAAT,MIR-137 | 210 | 46 | 17377 | 1707 |
RUNX2,DUSP8,BMPR2,RHOBTB1,MORC4,FAM117B,MGAT5B,SATB1,NOVA1,ABHD6,HMCN1,TBC1D19,MCU,PPM1E,FLRT3,LIMCH1,PRR16,FMNL2,C15orf41,KCNB2,ZNF385A,RPS13,MEIS2,ESRRG,SHANK2,ADCY1,PRDM1,CTTNBP2NL,ATP1B1,FNDC3A,PLCB1,ASPH,SLC46A3,DEXI,MAPKAPK2,RANBP2,HLF,BACH2,KLF12,PDLIM3,THBS4,NRP1,PPARGC1A,FNBP1L,MMP16,NR3C2 |
| 1.460e-07 | -15.74 | KIM_WT1_TARGETS_12HR_UP | MSigDB lists | KIM_WT1_TARGETS_12HR_UP | 152 | 37 | 17377 | 1707 |
CREB3L2,ACSL1,ENO2,ZNF395,LGR4,ATP9A,RBFOX2,ZCCHC24,LRP4,EPS8,PSD3,ABAT,DDR1,MTUS1,DDIT4,CDR2L,RUNDC3B,KLF9,ST8SIA1,SERPINH1,TLN2,IL1RAP,SNAI2,MN1,MSX1,RHOQ,FERMT2,ATP1B1,FGFR1,HEG1,TBC1D2,SMAD3,CSF1,P4HA2,P4HA1,GRB10,ATP2B4 |
| 1.460e-07 | -15.74 | CSR_LATE_UP.V1_DN | MSigDB lists | CSR_LATE_UP.V1_DN | 152 | 37 | 17377 | 1707 |
LONRF1,PLBD2,CFH,PRSS12,FAM131C,LDLR,ASS1,SCD,GAS6,DDX60L,GAS1,QPRT,IDI1,HMGCS1,MSMO1,SLC22A18,STARD4,PRKG1,NBEA,TOX,EPHB6,KLHL29,TSPAN9,GFRA1,HMGCR,FADS1,MVD,SNTB1,TSKU,DYRK1B,IRS2,GSN,INSIG1,GYPC,DYNC2LI1,DHCR7,MME |
| 1.526e-07 | -15.70 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | 56 | 20 | 17377 | 1707 |
FGFR4,MN1,ANK2,MORC4,ASS1,COL18A1,PRKAR2B,TMEM47,SPATS2L,ABAT,PRKCA,INPP1,IRS2,KCNS3,SGK1,MARCH3,JAKMIP2,MET,VWA5A,TBC1D9 |
| 1.589e-07 | -15.66 | plasma membrane region | cellular component | GO:0098590 | 1070 | 152 | 18223 | 1724 |
CACNG3,GRIK2,LDLR,HMCN1,NCS1,NOS1AP,EPCAM,SLC22A18,MARVELD2,ITGB3,CNNM2,LIN7A,PACSIN1,TSHR,CPE,PDGFRB,SLC3A2,ATF4,ABCC4,WLS,ANK2,TGFA,LRRK2,ABCC2,PLEKHA1,ENPP1,ATP7B,OXTR,SPRY4,TPM1,LZTS1,SCN5A,FN1,BVES,GABRB2,ITGA6,TJP1,MLC1,BBS9,SPIRE1,CA2,SEMA4F,FLRT3,LRP6,GRIP1,CADPS2,MPDZ,SLCO4C1,STXBP1,RIMS2,GPR161,CHRM3,NOS3,PAK1,EPB41L5,DISC1,MYO10,PARD3B,HOMER2,SPATA13,WWC1,HIP1,SNAP25,CPEB1,BAIAP2,DAGLA,GRIK4,RIPOR2,FCHO2,MPP2,CDH17,PLD1,CDH2,TESC,AMOTL1,DNM3,TCTN2,ST14,ADD2,KCTD12,NRXN1,LCP2,PRR7,CBLN1,CTNNA2,EPB41L3,CHRNA5,UNC13B,CNKSR3,ADGRL1,MAP7,PDE4D,RAB27B,MET,DOCK8,TMEM67,SHANK2,CHRNA6,NLGN4X,ATP1B1,DSP,GABARAPL1,PATJ,CAMK2N1,PTPRJ,PEMT,HPGD,PTPRS,DISP1,BMPR1A,TNIK,MYO1D,ROBO2,BMPR2,LRP4,APBB1,EPS8,CLSTN2,GABRG2,PSD3,GABRR2,P2RY1,SLC12A6,PKN1,KCNC4,NEDD4,FSD1,KCNJ4,EHD3,DSG2,PRKG2,MYO6,SPRY2,ATP2B1,DLGAP1,LZTS3,SLC40A1,RAPGEF2,GRID1,FERMT2,ARHGAP32,LEPR,HOMER3,FGR,SLC7A5,SVIL,GRIN2D,DLG2,OCLN,SLC16A10,ATP2B4,SNPH |
| 1.602e-07 | -15.65 | regulation of developmental process | biological process | GO:0050793 | 2569 | 320 | 17256 | 1658 |
ACVR1,LGR4,LDLR,GATA3,STAT5B,CEBPA,PRKCA,RAC3,STK24,NCS1,TRPS1,SKI,TYMP,TGFBR3,RAP2A,PACSIN1,NKX2-1,MEIS2,ACVR1C,DCC,LRRK2,FEZ1,AGO4,ACVR2B,SAV1,GPC6,ENPP1,WIPF3,NCKAP1L,CCBE1,PLK2,ALDOA,ADRB1,BMP1,SEMA3C,SERPINI1,INPP5F,TPM1,NRP1,SPART,VASH2,MEF2C,EFNB2,LATS2,CELSR1,PTPRD,ZHX3,FOXG1,IL17D,CHN1,CNTN4,APLF,MYC,FLRT3,C1QL4,PRELID1,GRIP1,TOX,TSPAN12,FMNL2,RIMS2,GPR161,ZNF385A,HMGCR,EPB41L5,PTCH2,FADS1,ENAM,BDNF,DISC1,PNP,MYO10,VLDLR,NSD2,SMARCD3,PLS1,SNAP25,PLCB1,THBS4,SFMBT1,HOXD13,CDH2,SHTN1,EPHA3,NBL1,BTC,DNM3,RHOD,PLXNA2,MSR1,PKP2,NRXN1,EPB41L3,TLR3,DACT1,DAB2IP,ZNF365,FZD1,SSH3,MYLK3,FZD4,ADM2,NKX3-2,SHANK2,PREX1,PRKCQ,WNT11,ATOH1,FGFR1,SNCA,CXCL10,IKZF3,PRKCB,APELA,WWTR1,KLF5,BMPR1A,COBL,WASF3,ROBO2,PLAG1,EPS8,GAS6,PKN1,EPHB1,ZNF219,GDPD5,PHLDA2,NEDD4,ADGRB2,HOPX,LRRN1,BHLHA15,GHR,FIG4,YBX3,ERRFI1,GFI1,SPRY2,ZFP36L2,FES,PDLIM7,TRPM4,VEGFC,LZTS3,RAPGEF2,RACK1,CEBPB,TRIB3,ID3,FGR,TERT,AKT3,XBP1,BMP4,SHOX2,DDIT3,FOXA1,TLL2,TRIM16,FGF13,LILRB1,F3,RND2,EOMES,GRHL1,ITGB3,CTTN,TLR4,IL1RAP,SLIT2,PDGFRB,RASGRP1,PRKACB,CYP1B1,DBN1,GCNT2,COL4A3,CEMIP2,YAP1,ROR1,PLEKHB1,GPRC5B,INSIG1,HPSE,MAP2,TNFRSF1A,OXTR,DLX2,PPARGC1A,TNFSF4,MAGI2,MLLT3,BCL11B,UST,RUNX2,FN1,LGALS3,BVES,RHOBTB1,UBASH3B,JDP2,CHADL,SPINK5,EFEMP1,NUMBL,KIAA1958,SEMA4F,CA2,ABCA5,GATA2,LRP6,ADCY6,BNIP3,NOS3,PAK1,RHOQ,SLITRK2,MSTN,EFNA3,WWC1,MAFB,SLITRK5,PRDM1,SDK1,BAIAP2,NEGR1,RIPOR2,ADGRB3,HEYL,CSF1,HK2,SEMA3A,TESC,SIX2,SFN,PRKN,ZSWIM5,ID1,DOCK1,CELSR3,IL15,RBFOX2,HECW2,NTRK3,BCL6B,CBLN1,SEMA6A,PPP1R9A,CTNNA2,SCIN,CD53,PDZD8,ADGRL1,BCL6,ACVR2A,WWC2,ZNF488,SNAI2,GLI1,CTH,IGFBP3,PRAME,PHLDB2,CSN2,PTPN6,VIM,SYNJ2BP,RARRES2,AMIGO1,CD40,DOCK5,WARS,SMAD3,NRG3,RBPMS2,PTK7,GBP1,PTPRS,HGF,HEY1,CNTN1,TNIK,BMPR2,APBB1,LRP4,TNFSF13B,CLSTN2,OVOL2,BMP6,ARHGAP44,NKX6-1,FOXP2,SCN1B,STC2,KIAA0319,TFAP2A,PRICKLE2,SH3PXD2B,IQGAP3,TESPA1,SYK,SLC45A3,MSX1,KDM5B,PRICKLE1,FERMT2,ZFPM2,DKK1,MAP1B,DDAH1,DOCK7,MYADM,FAT4,RND3,FBN1,CTSV,MYRF,PAX9,ABCG1 |
| 1.622e-07 | -15.63 | ERB2_UP.V1_UP | MSigDB lists | ERB2_UP.V1_UP | 178 | 41 | 17377 | 1707 |
CREB3L2,MYO1D,PCSK1N,ENO2,FGF13,GALNT12,CA8,FAM174B,BACE2,KMO,ALDOC,OPN3,BCL6,CADPS2,LIMCH1,PDE4D,PTPRE,ZNF365,HSPA2,TBC1D8,CYP1B1,FGFR4,UROS,PNRC1,PTPRU,MVD,CAPN5,BNIP3L,PACSIN3,NPC2,ASPH,PLEKHB1,TPK1,CAMK2N1,P4HA2,KIAA0513,MAOA,CLMN,ABCG1,HEY1,RRAGD |
| 1.678e-07 | -15.60 | VECCHI_GASTRIC_CANCER_EARLY_DN | MSigDB lists | VECCHI_GASTRIC_CANCER_EARLY_DN | 322 | 62 | 17377 | 1707 |
STOX2,CFH,CKAP2,SETBP1,KIF5C,SLC36A4,NTRK3,ABAT,DNER,BEX2,GAS1,PPP2R3A,PCDH7,EFEMP1,RNF180,FUT9,BCHE,GPR155,GHR,CHRDL1,SLC2A12,BNIP3,KLF9,NCAM1,FIGN,JAM2,CPE,MYRIP,SLIT2,PRKACB,CHRM3,CYP1B1,SYNPO2,GCNT2,THSD4,ESRRG,ALDH1L2,VLDLR,DNAJC6,TMEM47,ARRDC4,TTLL7,LEPR,EBF1,HLF,SH3GL2,WIPF3,PELI2,RBPMS2,GNAO1,MAP9,HPGD,MAOA,SERPINI1,TMEFF2,TNFRSF17,SUSD4,MAGI2,LIFR,NR3C2,AMPD1,CNTN1 |
| 1.690e-07 | -15.59 | GO_CYTOSKELETAL_PROTEIN_BINDING | MSigDB lists | GO_CYTOSKELETAL_PROTEIN_BINDING | 777 | 121 | 17377 | 1707 |
PHACTR3,CGN,SORBS1,FGF13,AKAP5,PSTPIP2,KIF5A,MYO1B,ADD2,COBLL1,ENAH,KIF21B,TNKS1BP1,PPP1R9A,CTNNA2,SCIN,PLS3,EPB41L3,KCNN2,ALDOC,REEP1,MYO3B,POF1B,JAKMIP2,MYH15,MARCKS,PACSIN1,TLN2,RCAN3,RAB27B,JAKMIP3,MYRIP,NEB,GLI1,DBN1,SSH3,TMEM67,GAPDH,EVL,KLHL3,KLHL4,CAP2,ANK2,DSTN,LRRK2,FEZ1,TNS1,COTL1,TTLL7,EML1,SNCA,GABARAPL1,GSN,IFT81,PDLIM3,MAP2,WIPF3,GBP1,ALDOA,TMOD2,TPM1,PPARGC1A,COBL,MID1,FRMD5,WASF3,MYO1D,SCN5A,INPPL1,FARP1,EPS8,APBB1,OPHN1,KIF5C,SORBS3,ADSSL1,PFN2,DYNC1I1,SPIRE1,FHOD3,RAB11FIP5,ABLIM1,MAP1A,EEF2,CACNB2,GAS2L3,SMTN,SGK1,LIMCH1,IQGAP3,MYO6,FMNL2,FES,NOS3,DPYSL5,EPB41L5,MICAL2,MID2,DISC1,SYNPO2,PXN,RAB3B,MYO10,RAB6B,SPATA6,SYBU,PACSIN3,OBSCN,HIP1,PHACTR2,PLS1,PALLD,SNTB1,BAIAP2,MAP1B,PLEKHH2,SVIL,CLMN,KIF21A,KIF1B,AMPD1 |
| 1.733e-07 | -15.57 | GO_ACTIN_FILAMENT_BASED_PROCESS | MSigDB lists | GO_ACTIN_FILAMENT_BASED_PROCESS | 425 | 76 | 17377 | 1707 |
ARHGAP26,SORBS1,RHOD,GPR65,MYO1B,PKP2,ADD2,COBLL1,DOCK2,RAC3,PPP1R9A,SCIN,EPB41L3,RAP2A,BCL6,MARCKS,CTTN,PACSIN1,NEB,PDGFRB,DBN1,FER,MYLK3,EVL,ANK2,DSTN,FGF12,PREX1,VIM,GJC1,GSN,PDLIM3,NCKAP1L,WIPF3,PTK7,ALDOA,TMOD2,TPM1,COBL,WASF3,TNIK,SCN5A,INPPL1,ARHGEF11,EPS8,OPHN1,SORBS3,PFN2,FHOD3,SPIRE1,FRY,SCN1B,CACNB2,GAS2L3,PRKG1,LIMCH1,MYO6,FMNL2,EPB41L5,PAK1,PDLIM7,MICAL2,RHOQ,NUAK2,OBSCN,RYR2,PLS1,CDC42BPA,PALLD,BAIAP2,RND3,FAT1,IQSEC2,FNBP1L,NPHP1,CACNA2D1 |
| 1.777e-07 | -15.54 | CHYLA_CBFA2T3_TARGETS_UP | MSigDB lists | CHYLA_CBFA2T3_TARGETS_UP | 366 | 68 | 17377 | 1707 |
ID1,GPR65,PPFIBP2,ASS1,SLCO3A1,FKBP11,TMEM53,EEPD1,ATRNL1,GSTM3,RAB27B,GCA,KCNIP3,WLS,DSTN,PRKCQ,PLEKHA1,PTPRJ,TMEM150B,HPSE,GPR160,ERN1,TNFRSF1A,PAM,HPGD,GPT2,KLF8,STOX2,PRSS16,ALOX5AP,RHOBTB1,BACE1,CYP2J2,UBASH3B,ELOVL7,ADSSL1,GRPEL2,MTUS1,RASSF8,RAB11FIP5,RNF180,RALGPS2,EHD3,SLC16A9,SLC6A15,ALPK1,MAST4,GFI1,C15orf41,GFRA1,LRP12,B4GALT6,RHOQ,GSTM2,PARD3B,C1R,HOMER3,EBF1,CEBPB,ICA1,PELI2,C1orf21,RAB31,UACA,SH3BGRL2,FNBP1L,DOCK9,ABCG1 |
| 1.872e-07 | -15.49 | GO_REGULATION_OF_GTPASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_GTPASE_ACTIVITY | 650 | 105 | 17377 | 1707 |
EPHA3,ARHGAP26,BTC,RASAL2,DOCK1,GPR65,ARHGAP22,RGS20,NTRK3,DOCK3,FAM13A,DENND3,SNX9,DOCK2,TBC1D30,TIAM2,TBC1D19,ARHGEF10L,ADPRHL1,SIPA1L2,BCL6,DAB2IP,RAPGEF5,SLIT2,RASGRP1,DOCK8,PDGFRB,TBC1D8,TNK2,LRRK2,PREX1,ELMOD1,WNT11,FGF17,CD40,DOCK5,TBC1D16,SERGEF,FGFR1,ARHGEF26,IRS2,ARHGAP21,NCKAP1L,RASGRF2,PLEKHG1,RGS10,ADRB1,ARHGAP28,DENND5B,RGS16,FARP1,STXBP5L,ARHGEF11,TBC1D1,BVES,ITGA6,IPO5,OPHN1,PSD3,ARL2,RGS7,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,RALGPS2,MCF2L,PRKG1,SRGAP1,RALGAPA2,IQGAP3,NCAM1,ERRFI1,TBC1D9,DENND1C,SPRY2,GFRA1,FGFR4,VAV3,RIN2,ARAP2,TBC1D8B,MCF2L2,RAPGEF2,CYTH3,RAPGEF4,ASAP3,SPATA13,OBSCN,RASA3,AGAP2,ARHGAP32,PLCB1,TBC1D2,DOCK7,GNAO1,SH3BP4,PTPRN2,GRIN2D,IQSEC2,FNBP1L,TBC1D4,DOCK6,DOCK9 |
| 1.877e-07 | -15.49 | V$CDC5_01 | MSigDB lists | V$CDC5_01 | 232 | 49 | 17377 | 1707 |
BCL11B,LRFN5,KLF8,MXI1,RASAL2,BMPR2,PLAG1,ADAMTS6,CREB5,NOVA1,ARHGAP44,TRPS1,FOXP2,ZNF827,ABLIM1,KCTD15,CHRNA5,CHRDL1,SGK3,BCL6,LIN7A,HRK,PPP2R2B,ERRFI1,HSPA2,C15orf41,GFRA1,PRKACB,FES,NKX2-1,MN1,MSX1,KLHL4,ESRRG,PRDM13,FGF12,CTTNBP2NL,ATOH1,ZFPM2,NAP1L5,BACH2,KLF12,C1orf21,INPP4B,ZBTB20,DLG2,PPARGC1A,NRP1,FOXA1 |
| 1.907e-07 | -15.47 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_UP | 179 | 41 | 17377 | 1707 |
CARS,LGALS3,DUSP8,CFH,GPR65,SLK,ARL15,MLF1,FAM198B,CHSY1,SFXN3,HOPX,TBC1D19,RAB11FIP5,EOMES,ZNF438,ZFYVE28,FAM84B,PPP2R2B,FAR2,GFI1,PERP,LRP12,MICAL2,SLC36A1,COL4A4,MPP1,HOMER2,FERMT2,ATP1B1,FBXO36,PLCB1,HLF,PRCP,WWTR1,PLEKHG1,B3GALT2,PAM,KIF21A,ATP2B4,STOM |
| 1.966e-07 | -15.44 | V$GATA6_01 | MSigDB lists | V$GATA6_01 | 246 | 51 | 17377 | 1707 |
TYRO3,SORBS1,RUNX2,TCP11L2,ENO2,PLXNA2,CREB5,SEZ6L2,ZNF219,BMP6,TRPS1,ARHGEF10L,EPB41L3,PPM1E,CACNB2,GPR155,LHX6,FAM107B,HS3ST5,SRGAP1,BCL6,TSC22D1,ADCY6,TSPAN12,ERRFI1,GATM,C15orf41,DOCK8,TNK2,CARD6,ARAP2,SLITRK2,COL4A3,KCNH5,COL4A4,ESRRG,LRMP,WNT11,ZFPM2,HOXA1,LEPR,SLC39A14,KLF12,SPRY4,PPARGC1A,CDH2,STON2,MID1,FOXA1,PKIA,MEF2C |
| 2.044e-07 | -15.40 | SMID_BREAST_CANCER_LUMINAL_B_DN | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_B_DN | 518 | 88 | 17377 | 1707 |
PLA2G4A,DNM3,UGT8,TRIM2,ID1,GALNT12,ASS1,NDRG2,CHAC1,COL14A1,DOCK2,CHRDL1,MPPED2,PROS1,PCOLCE2,SERPINH1,MET,PLTP,PERP,LAMP3,IGFBP3,HRASLS,CYP1B1,PGBD5,VNN2,ITGB7,ABCC4,WLS,ANK2,LRMP,CR2,ABCC2,COTL1,WARS,ISG20,BCL11A,TCF7L1,CXCL10,TDO2,PRKCB,GBP1,PTK7,WWTR1,KCNG1,KLF5,APBA2,MID1,RRAGD,BCL11B,SV2B,COL9A3,IL32,CKAP2,GRB14,ITGA6,STXBP6,SELL,IGF2BP2,CD7,PHGDH,SEL1L3,FHOD3,EFEMP1,BACE2,SLC6A15,ST8SIA1,PTPRCAP,RRAS2,GPR161,CHRM3,FERMT2,LEPR,GPR19,MAP1B,ZIC1,DKK1,GALNT3,PTPRC,CD37,PLAGL1,RND3,FAT1,GEM,TNFRSF17,SHOX2,SFN,MME,CSRP2 |
| 2.047e-07 | -15.40 | human chr5q35.3 | chromosome location | human chr5q35.3 | 85 | 22 | 26185 | 1967 |
PDLIM7,DBN1,BTNL9,MGAT4B,RACK1,GRK6,F12,CANX,NHP2,PRR7,AACSP1,ZFP62,NSD1,ZNF354A,MGAT1,LINC00847,PRELID1,PHYKPL,LMAN2,TMED9,RNF130,B4GALT7 |
| 2.065e-07 | -15.39 | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | 186 | 42 | 17377 | 1707 |
BCL11B,DMXL2,MXI1,LGALS3,FN1,ST14,TBC1D1,SLC1A3,RTN1,TYMP,KMO,ABCA5,MGAT1,DACT1,FAM168A,BCL6,TSC22D1,DHRS12,LIMCH1,MARCKS,IPCEF1,FIG4,PTPRE,CKAP4,LAMP3,ZNF629,VNN2,ARAP2,RHOQ,KLHL3,SMARCD3,SYNJ2BP,PLEKHA1,NPC2,ZNF266,BACH2,PELI2,SLC2A6,WDR19,RNF130,DDIT3,CRYL1 |
| 2.115e-07 | -15.37 | BENPORATH_PRC2_TARGETS | MSigDB lists | BENPORATH_PRC2_TARGETS | 612 | 100 | 17377 | 1707 |
SIDT1,SYT12,MCOLN3,OTX1,RGS20,PLXNA2,GATA3,ANKRD18A,MAPK4,DACH2,CBLN1,CYP26A1,PPM1E,EOMES,KCNAB1,ZFYVE28,COL25A1,LHX6,HRK,TMEM132E,SLIT2,ANKRD18B,NKX2-1,ANKRD20A3,PTPRU,DCC,NKX3-2,FAM84A,GJB2,ELMOD1,FEZ1,WNT11,ATF3,KCND3,ATOH1,BATF3,HTR7,TRIM9,CAMK2N1,MSC,IKZF3,RGS10,ADRB1,TMOD2,HS3ST3B1,DLX2,TMEFF2,SUSD4,NEUROG2,MLLT3,SPOCK3,CTNND2,HS6ST3,HEY1,KCNV1,LRFN5,SV2B,LGALS3,STXBP6,RIMKLA,CLSTN2,COL4A5,FAM81A,EPHB1,KCNC4,FOXG1,HPCAL4,COL27A1,NKX6-1,SLC30A4,GATA2,GHR,PRKG1,NCAM1,BARX1,COL9A2,NDUFA4L2,RAX,ANKRD20A2,UNC5C,MSX1,KCNQ3,SLC27A2,CACNA1E,TCEA3,EFNA3,GRID1,MAFB,ILDR2,ZIC1,DKK1,MKX,DPY19L2,DDAH1,SLCO5A1,HOXD13,PAX9,SHOX2,NKX2-8,SIX2 |
| 2.200e-07 | -15.33 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_UP | 167 | 39 | 17377 | 1707 |
PLA2G4A,DMXL2,RHOBTB1,PTPRD,ARHGAP22,NKAIN2,HERC5,HERC6,DDX60L,QPRT,HOPX,MECOM,RTN1,APLF,FRAS1,MAP7,TOX,SCN2A,RAB27B,PARP9,PTPN13,ARID5B,ATP1B1,ARRDC4,TTC28,NEGR1,TRIM9,CXCL10,GBP1,NCOA7,ADRB1,INPP4B,KIAA0513,KLF5,CMPK2,OSBPL6,MLLT3,ACSM3,HEY1 |
| 2.212e-07 | -15.32 | ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | 420 | 75 | 17377 | 1707 |
DMXL2,ACSL1,RASAL2,LDLR,SLC2A13,CA8,SLCO3A1,SEMA6A,EYA4,HECTD2,F3,KCNAB1,CNKSR3,ACVR2A,MARCKS,ARL4D,SEMA6C,GPM6A,TMEM67,CD55,PNRC1,KLHL3,KLHL4,VIM,TNS1,ATP1B1,CA13,BCL11A,SLC39A14,CXCL10,MSC,IQCH,RCN3,KLF5,TNFSF15,HGF,DNHD1,LIFR,STON2,COBL,HEY1,RGS16,DYRK3,ITPRIP,REL,ELOVL7,NLRP14,PSD3,GPR180,BTBD9,DYNC1I1,FOXP2,FRY,SCN1B,PRKCD,SRGAP1,SMTN,SLC6A15,TBC1D9,ATP2B1,DUSP1,MN1,RAB6B,NR4A1,RAPGEF2,LITAF,WWC1,FERMT2,PALLD,MAP1B,RND3,MFSD2A,SLC2A6,SVIL,KIF1B |
| 2.239e-07 | -15.31 | V$HFH3_01 | MSigDB lists | V$HFH3_01 | 180 | 41 | 17377 | 1707 |
TYRO3,BCL11B,ID1,RUNX2,C1QTNF3,SCAMP1,CHCHD7,GRIK2,PLAG1,TJP1,CEBPA,CADM2,COLEC10,DOCK3,NOVA1,TSPAN17,NEDD4,FOXP2,ATXN7L1,KCTD15,SLC10A7,SGK1,NCAM1,ETV1,GFRA1,DUSP1,SSH3,CRIM1,SLC39A8,NFIA,PRDM1,KLF12,GNAO1,MCC,TNFSF15,CAB39L,DLG2,SHOX2,NR3C2,MID1,MEF2C |
| 2.294e-07 | -15.29 | LE_EGR2_TARGETS_DN | MSigDB lists | LE_EGR2_TARGETS_DN | 106 | 29 | 17377 | 1707 |
FADS1,MYO1D,CD55,UGT8,MGST3,TGFA,MVD,MYO1B,DHCR24,SLCO3A1,SNCA,GNAI1,CYP51A1,RTN1,HMGCS1,IDI1,NACC2,MSMO1,OSBPL5,LIMCH1,MPDZ,SLC6A15,EPHB6,ERRFI1,SLC1A5,GFRA1,SEMA6C,TMEM56,HMGCR |
| 2.305e-07 | -15.28 | WANG_MLL_TARGETS | MSigDB lists | WANG_MLL_TARGETS | 275 | 55 | 17377 | 1707 |
ARHGAP26,RGS16,STOX2,MRC2,IGFBP6,RNF144A,GALNT12,STXBP6,GATA3,ZIC2,NOTUM,SLC7A2,FAM13A,COL14A1,NKX6-1,TGFBR3,ABI3BP,CNKSR3,SCARF2,CNNM2,GRIP1,TOX,ETV1,JAM2,SLIT2,ATP2B1,FES,TBC1D8,PNMA2,VEGFC,ALDH2,EIF4E3,COL6A2,ARID5B,NFIA,MAFB,FNDC3A,NT5DC2,SMPDL3B,NEGR1,EBF1,ENPP1,HLF,PCDHB7,PELI2,MAPK13,GRB10,KIF21A,PAX9,DLX2,RNF130,SHOX2,PTGES,FRMD5,MME |
| 2.358e-07 | -15.26 | LI_CISPLATIN_RESISTANCE_DN | MSigDB lists | LI_CISPLATIN_RESISTANCE_DN | 30 | 14 | 17377 | 1707 |
CFH,ROBO2,TDO2,TES,CFHR1,FZD8,CHRDL1,DSEL,MARCKS,BCAN,SKAP1,FOXG1,SEMA6A,PCDH7 |
| 2.414e-07 | -15.24 | GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP | MSigDB lists | GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP | 187 | 42 | 17377 | 1707 |
EXPH5,ANO10,TBC1D1,DOCK1,RECK,UBASH3B,GATA3,RNF24,CHSY1,LCP2,PHGDH,DOCK2,RND2,NAV1,MCF2L,KAZN,PCBP4,GHR,CCDC122,TLR4,FMNL2,DOCK8,PAK1,EBPL,PNRC1,SPATA6,STAT4,SPATA13,CALCRL,C1R,PDE8A,FRK,SESN1,CRYBG3,RERE,PYCR1,CD37,NCKAP1L,WFS1,NRP1,VASH2,LPP |
| 2.460e-07 | -15.22 | plasma membrane bounded cell projection part | cellular component | GO:0120038 | 1369 | 185 | 18223 | 1724 |
FGF13,GRIK2,PRSS12,KIF5A,NDRG2,DNER,RAC3,NCS1,TUBB4A,MOK,KCNAB1,KCNN2,DNAH6,ITGB3,GSTM3,CTTN,PACSIN1,MYRIP,PRKACB,DBN1,GPM6A,KCNIP3,ATF4,WLS,LRRK2,FEZ1,PRKAR2B,EFHC1,ABCC2,KCND3,ROR1,PLEKHA1,TRIM9,MAP2,PLK2,TMOD2,INPP5F,SPRY4,TPM1,NRP1,DNHD1,PPARGC1A,APBA2,MAGI2,SLC9B1,LZTS1,PRKAA2,BVES,SCN8A,OPHN1,APBA1,PFN2,BBS9,TTC30B,NAV1,PDZD7,FLRT3,OPN3,GRIP1,MPDZ,BNIP3,MORN4,GPR161,ZNF385A,CHRM3,EPB41L5,PAK1,DPYSL5,BDNF,DISC1,KCNQ3,MYO10,SPATA6,HOMER2,SPATA13,WWC1,CATSPERE,SNAP25,OR11H4,SPATA7,BAIAP2,CPEB1,DAGLA,RIPOR2,RPL28,SH3GL2,WDR19,MPP2,DYNC2LI1,PTPRN2,SEMA3A,TESC,SHTN1,MME,DNM3,TCTN2,C4A,ABHD13,CANX,KIF21B,PRR7,TBC1D30,PPP1R9A,TIAM2,CCDC120,EPB41L3,GPRIN1,UNC13B,MYO3B,ADGRL1,DAB2IP,SCN2A,DNAH5,KCNB2,DOCK8,GLI1,INTU,TMEM67,FZD4,SHANK2,PREX1,NLGN4X,CBY1,AMIGO1,CD40,TTLL7,GABARAPL1,SNCA,CAMK2N1,HTR7,ARMC4,IFT81,PTPRJ,PEMT,WFS1,ITGA2,RGS10,BMPR1A,ATG5,CTTNBP2,COBL,CTNND2,MYO1D,NECAB2,FARP1,ROBO2,BMPR2,APBB1,EPS8,BLVRB,LRP4,GABRG2,KIF5C,PSD3,P2RY1,EPHB1,KCNC4,GDPD5,ARHGAP44,NEDD4,MAP1A,SCN1B,EHD3,TRIM3,DYNC2H1,NPTXR,MYO6,SPRY2,ATP2B1,B9D1,SYBU,FERMT2,ARHGAP32,RACK1,PALLD,HOMER3,MAP1B,FGR,DOCK7,TMEM237,GNAO1,DLG2,NPHP1,KIF1B,ATP2B4 |
| 2.460e-07 | -15.22 | cell projection part | cellular component | GO:0044463 | 1369 | 185 | 18223 | 1724 |
FGF13,GRIK2,PRSS12,KIF5A,NDRG2,DNER,RAC3,NCS1,TUBB4A,MOK,KCNAB1,KCNN2,DNAH6,ITGB3,GSTM3,CTTN,PACSIN1,MYRIP,PRKACB,DBN1,GPM6A,KCNIP3,ATF4,WLS,LRRK2,FEZ1,PRKAR2B,EFHC1,ABCC2,KCND3,ROR1,PLEKHA1,TRIM9,MAP2,PLK2,TMOD2,INPP5F,SPRY4,TPM1,NRP1,DNHD1,PPARGC1A,APBA2,MAGI2,SLC9B1,LZTS1,PRKAA2,BVES,SCN8A,OPHN1,APBA1,PFN2,BBS9,TTC30B,NAV1,PDZD7,FLRT3,OPN3,GRIP1,MPDZ,BNIP3,MORN4,GPR161,ZNF385A,CHRM3,EPB41L5,PAK1,DPYSL5,BDNF,DISC1,KCNQ3,MYO10,SPATA6,HOMER2,SPATA13,WWC1,CATSPERE,SNAP25,OR11H4,SPATA7,BAIAP2,CPEB1,DAGLA,RIPOR2,RPL28,SH3GL2,WDR19,MPP2,DYNC2LI1,PTPRN2,SEMA3A,TESC,SHTN1,MME,DNM3,TCTN2,C4A,ABHD13,CANX,KIF21B,PRR7,TBC1D30,PPP1R9A,TIAM2,CCDC120,EPB41L3,GPRIN1,UNC13B,MYO3B,ADGRL1,DAB2IP,SCN2A,DNAH5,KCNB2,DOCK8,GLI1,INTU,TMEM67,FZD4,SHANK2,PREX1,NLGN4X,CBY1,AMIGO1,CD40,TTLL7,GABARAPL1,SNCA,CAMK2N1,HTR7,ARMC4,IFT81,PTPRJ,PEMT,WFS1,ITGA2,RGS10,BMPR1A,ATG5,CTTNBP2,COBL,CTNND2,MYO1D,NECAB2,FARP1,ROBO2,BMPR2,APBB1,EPS8,BLVRB,LRP4,GABRG2,KIF5C,PSD3,P2RY1,EPHB1,KCNC4,GDPD5,ARHGAP44,NEDD4,MAP1A,SCN1B,EHD3,TRIM3,DYNC2H1,NPTXR,MYO6,SPRY2,ATP2B1,B9D1,SYBU,FERMT2,ARHGAP32,RACK1,PALLD,HOMER3,MAP1B,FGR,DOCK7,TMEM237,GNAO1,DLG2,NPHP1,KIF1B,ATP2B4 |
| 2.479e-07 | -15.21 | cytoplasmic part | cellular component | GO:0044444 | 9540 | 1002 | 18223 | 1724 |
ARHGAP26,DOC2A,TRIM16L,ADAL,PDE1B,GRIK2,PRSS12,AASS,DNAJC3,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,STAT5B,CHAC1,NHP2,DOCK3,BCAN,SNX9,ABHD6,NOS1AP,PCDH7,EPDR1,TXNDC5,BAG3,FBXO32,PMAIP1,DNAH6,PPFIA2,RAP2A,RAB26,TMED9,PPP2R2B,COG3,CPE,SMIM20,EIF4E3,MEIS2,SMAD9,DCC,WLS,CAP2,EXOC6B,DSTN,TGFA,GJB2,LRRK2,ELMOD1,HACD1,MSRB3,FEZ1,PRKAR2B,F12,CA13,PYCR1,ENPP1,WIPF3,ATP7B,MAP9,ALDOA,BDH2,ADRB1,ARHGAP28,BBC3,CAB39L,TMOD2,INPP5F,TPM1,DNHD1,LPP,CRYL1,CARS,SCN5A,LATS2,CYP2J2,SLK,TJP1,SLC36A4,GPSM2,BBS9,GRPEL2,CHN1,RSL24D1,BNIP1,FRY,BACE2,APLF,FLRT3,PRELID2,SRGAP1,LMAN2,CADPS2,ST8SIA1,NCAM1,DENND1C,MOXD1,AGL,STXBP1,FMNL2,RPS23,HMGCR,FADS1,ENAM,BDNF,SLC37A1,PNP,MYO10,STAT4,MGST3,FHL2,FASN,RYR2,HIP1,CALCRL,PLS1,ST6GALNAC3,SHISA2,SNAP25,ARRDC4,CLN5,SPATA7,CPEB1,DHX32,RIMKLB,GSTO2,SH3GL2,RPL28,QPCTL,SELENOM,LAPTM4B,FBXO27,CDH2,SHTN1,GVINP1,DOCK9,MTG1,TFCP2L1,NUDT10,DNM3,SCAMP1,SUGCT,GALNT12,GALNT6,C4A,MYO1B,LRRCC1,ABHD13,RGS20,ADD2,MAPK4,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,TLR3,KMO,EEF1AKMT2,CNKSR3,DACT1,COL25A1,ALDH1L1,MAGEA3,RTKN2,RPL26L1,JAKMIP3,SYNGR3,RAB27B,DNAH5,MYT1,SNX10,PERP,DOCK8,MYLK3,GARS,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,EBPL,PFKFB2,FZD4,NPM3,TRAM1L1,ADCY1,PXYLP1,RAB38,DSP,ASPH,METAP1D,FGFR1,GABARAPL1,GJC1,IRS2,ARHGAP21,GYPC,PDLIM3,WFS1,PEMT,LAMB1,WWTR1,INPP4B,PAM,RCN3,P4HA1,ALG11,HOXB9,RAB30,SERINC5,FARP1,ANKRD13B,GCAT,CKAP2,BACE1,FZD8,BIK,UBAC2,CBS,GAS6,P2RY1,PKN1,EPHB1,COL27A1,NEO1,HMGCS1,PCBP4,MCF2L,GHR,MORN2,MYO6,ZFP36L2,FES,PARP9,ULBP1,TRPM4,PDLIM7,B9D1,VEGFC,OPLAH,CLYBL,RAB6B,RAPGEF2,ELOVL3,RASA3,AK4,ATP11A,RACK1,GALNT3,PTPRC,TRIB3,RPL12,PLOD2,OSBPL5,SRD5A3,XBP1,PIP5KL1,HK1,BMP4,CMPK2,DOCK6,ATP2B4,BTRC,TPT1,CCDC126,NMNAT3,CACNG3,FGF13,TRIM16,SYT12,ASS1,NDRG2,HDGFL3,ITPR2,MGAT5B,FAM13A,PLS3,RND2,FKBP9,RPS6KA2,TM9SF2,KCNAB1,KCNN2,SEC16B,AADAT,HPS1,MARVELD2,ITGB3,TMEM143,COL19A1,JAKMIP2,TLR4,ENO1,NEB,DBN1,CD55,KCNIP3,SLC3A2,GCNT2,PNRC1,COL4A3,ABCC4,ANK2,ATOX1,GDPD1,NFE2L1,PLEKHA1,SESN1,SPNS1,TRIM9,TCF7L1,INSIG1,KLF12,MAP2,P4HA2,GNB4,CCDC146,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,RRAGD,CHMP4C,PRKAA2,LONRF1,TYRO3,RUNX2,LGALS3,HID1,CHCHD7,SETBP1,SORBS3,MLC1,PGAP1,DOK5,FHOD3,SPIRE1,RNF180,GALNT1,SEMA4F,ABCA5,BCHE,PDE10A,GAN,HS3ST5,LRP6,ADCY6,BNIP3,SLCO4C1,FAR2,CKAP4,PAK1,CHSY3,DPYSL5,NDUFA4L2,FGFR4,B3GLCT,SLC27A2,RNF170,HOMER2,MGAT4B,GPSM1,SPATA13,PPFIA4,STRADB,OBSCN,PDE8A,LDHD,BAIAP2,TBC1D2,MAPKAPK2,ATPAF2,MFSD2A,CSF1,PLD1,RNF122,TESC,MME,SFN,PRKN,ID1,AKAP5,DOCK1,LPCAT2,RBFOX2,XYLT1,RHPN2,RNF24,FAM198B,KIF21B,SEZ6L2,LPIN3,DENND3,FAM110B,PRR7,TNKS1BP1,PCLO,PPP1R9A,CTNNA2,CYP26A1,FAM131B,RIDA,IDI1,SLC22A17,TACC2,ZDHHC6,BCL6,ZDHHC23,MYH15,CLVS2,GLI1,IGFBP3,RPS13,CTH,EVL,TMEM67,EVA1A,TUBA1A,UROS,LRRC8B,NOP53,TMEM65,TDRD3,ACO1,RNF125,VIM,GSTO1,RARRES2,FRK,ETNPPL,JAM3,SMAD3,RANBP2,PTPRJ,RNF217,GBP1,ITGA2,PTPRS,MAOA,HGF,SEPT5,MBOAT2,RETREG1,ARFGEF3,MAN2B2,TENM1,COL9A3,DYRK3,LPAR2,IL32,GRB14,PAK5,KLHL13,RUSC2,APBB1,BLVRB,MCTP2,GABRG2,SELL,HBE1,RASD1,SFXN3,USP30,ARHGAP44,TTC1,TECPR1,MAP1A,FUT9,TFAP2A,SGK1,KLF9,PCK2,ESD,SYK,CES3,PCSK6,MOB1B,PPP1R3D,CRIP2,LITAF,PRICKLE1,FERMT2,EXOG,FNDC3A,PALLD,ILDR2,MAP10,HOMER3,DKK1,DDAH1,FBN1,FMO4,DLG2,MYRF,RPL4,SLC1A5,TBC1D4,PTGES,KIF1B,CACNA2D1,PPP4R4,PLBD2,ATP8A1,LDLR,VAMP8,PPFIBP2,ENAH,PRKCA,RAC3,AARS,NCS1,STK24,SLC9A7,HECTD2,TYMP,ZFYVE28,PALD1,KCNS3,CHRDL1,NDUFB8,GSTM3,SP140,PACSIN1,THSD1,GLDC,GDAP1,ERGIC1,WISP3,KLHL3,ALDH1L2,LRMP,DNAJC6,BNIP3L,AGO4,SLC25A28,EFHC1,ZDHHC14,SAV1,GPC6,ARHGEF26,GNAI1,AHRR,SFXN1,SH3RF1,NCKAP1L,PLK2,RASGRF2,ENTPD7,B3GALT2,BMP1,DSEL,SERPINI1,MAPK13,SPRY4,SPART,NRP1,KLF8,INPPL1,ALOX5AP,EHHADH,TBC1D1,GABRB2,SCN8A,ST6GAL1,DHCR24,OPHN1,SLC25A27,MRPL22,GTF2IRD1,ISYNA1,HERC6,APBA1,DYNC1I1,ADSSL1,CHD5,NIPSNAP3B,RPL13A,MYORG,MECOM,MTUS1,MCOLN2,GBGT1,SLC7A11,PIK3AP1,MSMO1,MYC,PRELID1,SREBF1,PRKG1,GRIP1,MPDZ,COL9A2,GPR161,RIMS2,RNF152,EPB41L5,RPL26,QSOX1,DISC1,SLC36A1,PLEKHA8,COL4A4,VLDLR,RAPGEF4,PACSIN3,COLGALT2,PEX5L,NPC2,RABAC1,PLCB1,FAM162A,TMEM74,PLEKHH2,VPS37D,PKN3,PMEPA1,PELI2,THBS4,DYNC2LI1,SQLE,DHCR7,SMYD3,AMPD1,ACSM3,PLA2G4A,FRMPD3,EPHA3,AMOTL1,PCSK1N,RASAL2,ELOVL4,RNF144A,RHOD,MSR1,CHUK,SPATS2L,COL14A1,NUDT12,TBC1D30,TIAM2,ZFYVE9,CCDC120,ASNS,ERG28,ZNF438,POU5F1B,ALDOC,STARD4,NBEA,DAB2IP,MARCKS,PDE4D,SERPINH1,GATM,GAB2,B3GALT1,PDK1,TMEM43,CYB5R2,SFXN4,SHANK2,PANK1,PREX1,PRKCQ,CBY1,TBC1D16,TRIQK,ATP10D,SNCA,PATJ,IKZF3,PRKCB,BEX3,TDO2,ASIC1,CCNA1,HPGD,KLF5,GRB10,HS3ST3B1,ATG5,MAPK10,CTTNBP2,NR3C2,MID1,STON2,COBL,DENND5B,HACE1,RPS20,MYO1D,ANKRD13D,MXI1,IGFBP6,GLIPR1L1,ATP9A,EPS8,ARL2,HERC5,NDFIP2,RGS7,SELENOP,GDPD5,TPD52L1,INPP1,SLC35G2,NEDD4,GSAP,RGS17,SOAT2,MGAT1,RMDN2,SGK3,PRKG2,RALGAPA2,PHYKPL,FIG4,CERS4,DYNC2H1,YBX3,ERRFI1,SEPT3,SMAD6,SPRY2,B4GALT6,PFKFB4,SLC40A1,VAV3,SYNPO2,PXN,ARAP2,ALDH2,ARHGEF28,GSTM2,HYKK,MPP1,AGPAT4,RPL21,TMEM126A,ZDHHC15,GUCY1A2,UCHL3,SKAP1,GPLD1,FGR,TERT,MCC,SVIL,PGM2L1,MYOM2,LRRK1,CERS1,B4GALT7,DDIT3,OCLN,LARP1,NUDT17,ATP1A3,EXPH5,MVK,ACSL1,KIF5A,UGDH,ABAT,CACNB4,DNER,ABHD4,HMCN1,CHST10,QPRT,GSDME,CYP51A1,TUBB4A,RTN1,ARHGEF10L,ADPRHL1,PPM1E,GRHL1,AKAP7,SLC10A7,SLC2A12,HRK,EPHB6,CTTN,MYRIP,GALNT18,FANK1,PRKACB,PDGFRB,RASGRP1,LAMP3,CYP1B1,ATL1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,SGK2,GRK3,SERGEF,EML1,AK1,GSN,TMEM150B,GPRC5B,HPSE,PPARGC1A,APBA2,MAGI2,SLC9B1,PCSK5,UST,GPT2,GPR63,SV2B,MOCOS,FN1,ZNF395,RHOBTB1,SEC24D,STXBP6,FBXO4,RIMKLA,ELOVL7,CYP4V2,ATP6V1E2,SCD,GALNT13,CHSY1,PHGDH,SPINK5,DDIT4,EEF2,SLC30A4,CA2,ZNF354A,RPS11,NCEH1,SNX7,NOS3,HBG2,IL17RD,ATP5IF1,PODXL2,RHOQ,SH2D2A,GSTM4,PARD3B,EDEM3,SDC3,WWC1,DUSP9,GALNT17,LHPP,B4GALNT3,STEAP1,AMDHD1,HERPUD1,GLCE,PLAGL1,FCHO2,FAT1,SH3BP4,RAB31,RAI14,HK2,PTPRN2,TMEM117,FNBP1L,OSBPL6,DIRC2,CREB3L2,DMXL2,SORBS1,IL15,PSTPIP2,PLEKHA5,ARHGAP22,COL18A1,TDRKH,LACC1,CANX,PIBF1,DOCK2,SCIN,CD53,COL22A1,UNC13B,PDZD8,SETDB2,ERO1B,RPS6KL1,KAZN,PPFIBP1,REEP1,FABP6,MAP7,STEAP3,FHIT,PROS1,WWC2,HSPA2,ALG10B,GCA,FER,PHLDB2,ANTXR2,PTPN6,MVD,TES,C3orf52,SYNJ2BP,TTLL7,DOCK5,WARS,TPK1,ARMC4,LMLN,TRIM34,KPNA3,BACH2,EIF4EBP1,RGS10,CYP2U1,PSPH,TNIK,PRSS16,ENO2,TSPAN15,CLGN,ARHGEF11,REL,TNFSF13B,NSUN6,CLSTN2,IGF2BP2,COL4A5,NOTUM,CUEDC2,MCU,RPL34,SYDE2,RAB11FIP5,KCNJ4,CHN2,PRKCD,EHD3,STC2,KIAA0319,ACTA2,MARCH3,TRIM3,AFAP1L2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,TESPA1,FKBP14,RIN2,USP2,RAB3B,KDM5B,NR4A1,CYTH3,SYBU,ASAP3,OGDHL,MARS,AGAP2,PHACTR2,ARHGAP32,TLR6,GALNT14,LRAT,MAP1B,CTIF,GPR37,SUGT1,ICA1,MYADM,EDA,RND3,NACC2,ACER2,PRCP,MAP2K6,CTSV,SLC7A5,UACA,KIF21A,RPS12,MAP3K20,NPHP1,MMP16,ABCG1,STOM,SNPH |
| 2.552e-07 | -15.18 | HALLMARK_CHOLESTEROL_HOMEOSTASIS | MSigDB lists | HALLMARK_CHOLESTEROL_HOMEOSTASIS | 73 | 23 | 17377 | 1707 |
ANTXR2,MVK,GSTM2,LGALS3,PNRC1,MVD,LDLR,FASN,CBS,SCD,ATF3,GNAI1,CYP51A1,TRIB3,HMGCS1,IDI1,ALDOC,STARD4,SQLE,ERRFI1,DHCR7,HMGCR,GLDC |
| 2.632e-07 | -15.15 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 2128 | 275 | 17385 | 1698 |
MYCBP2,ACVR1,LGR4,LDLR,NPM1,STAT5B,CTBP2,CEBPA,BCAN,PRKCA,KIAA1217,EYA4,STK24,TRPS1,BAG3,PACSIN1,ACVR1C,KLHL4,LRRK2,NFIA,EFHC1,ABCC2,TNS1,ACVR2B,SAV1,PLK2,BMP1,MAPK13,CRYL1,LATS2,INPPL1,FAM124A,APBA1,DYNC1I1,FRY,KIAA1671,ADCK1,PIK3AP1,APLF,CACNB2,ZIC5,PRKG1,GRIP1,TSPAN12,ALPK1,FAM84B,GPR161,HMGCR,EPB41L5,RAPGEF4,FASN,ZBBX,CDC42BPA,MMP15,CACHD1,PLEKHH2,PKN3,THBS4,DYNC2LI1,DOCK9,EPHA3,ST14,GALNT12,PKP2,CHUK,GRK6,DDR1,TIAM2,SPEG,ASNS,COL25A1,DAB2IP,DNAH5,VNN2,MYLK3,COL6A2,PDK1,PFKFB2,PRKCQ,TBC1D16,FGFR1,IKZF3,POPDC3,PRKCB,LAMB1,BMPR1A,COBL,DENND5B,ANKRD13D,GLIPR1L1,PRSS35,PKN1,EPHB1,TSPAN17,COL27A1,HMGCS1,SOAT2,LRRN1,SGK3,ZFP36L2,FES,TMC7,PFKFB4,PTPN13,GUCY1A2,ZIC1,GPLD1,PTPRC,TRIB3,FGR,AKT3,PGM2L1,NEK11,HK1,DOCK6,OCLN,TLL2,ATP1A3,MPZL3,KIF5A,PTPN21,FHDC1,TNFAIP8L2,MGAT5B,HMCN1,FSTL5,CCNJ,LGI2,FKBP9,RPS6KA2,AADAT,KCNN2,ANKFN1,LIN7A,COL19A1,TLN2,ENO1,TLR4,OR2W3,PDGFRB,PRKACB,DBN1,ITGB7,TNK2,ATL1,CD55,MARK1,SLC3A2,COL4A3,ABCC4,SPOCD1,ANK2,ZNF565,CR2,ROR1,SGK2,RNF44,TRIM9,DYRK1B,SPNS1,KCNMB4,HPSE,MAP2,P4HA2,ERN1,NCOA7,MAGI2,TC2N,PRKAA2,STXBP5L,ZNF395,RIMKLA,ATP6V1E2,SETBP1,SPINK5,DOK5,FHOD3,HSPA12B,KIAA1958,GALNT1,RNF180,IGF1R,GATA2,PDE10A,FRAS1,FBXL2,LRP3,SNX7,FGFR4,PAK1,SLITRK2,OBSCN,STRADB,WWC1,SDC3,PPFIA4,B4GALNT3,LDHD,MAPKAPK2,KIAA0355,FAT1,RAI14,TMEM117,DISP2,NKX2-8,SFN,NEK10,CELSR3,DOCK1,PLEKHA5,COBLL1,HECW2,TDRKH,NTRK3,RNF24,FAM198B,KIF21B,LPIN3,PCLO,TACC2,CDC14B,RPS6KL1,PPFIBP1,MYO3B,ACVR2A,MYH15,MET,HSPA2,GLI1,CTH,FER,EVL,TMEM65,MVD,CHRNA6,AMIGO1,FRK,CAMK2N1,TMPRSS9,PTK7,SUSD4,MAST1,TENM1,TNIK,DYRK3,BMPR2,ENO2,PRSS16,COL4A5,NOTUM,MCU,KCNJ4,MAP1A,PRKCD,DSG2,TFAP2A,ACTA2,SGK1,SH3PXD2B,SYK,PPP1R3D,USP2,HNF4G,NUAK2,ARHGAP32,MKX,ICA1,FAT4,L3MBTL4,MAP2K6,UACA,DLG2,KIF21A,SLC1A5,KIF1B |
| 2.745e-07 | -15.11 | neuron migration | biological process | GO:0001764 | 115 | 30 | 17256 | 1658 |
DISC1,GPM6A,MARK1,CELSR1,FGF13,CELSR3,DCC,RAPGEF2,GATA3,SATB2,NTRK3,ATOH1,GAS6,DNER,FOXG1,FGFR1,MAP1B,DDIT4,NKX6-1,NAV1,GATA2,LHX6,MATN2,KIAA0319,PRKG1,NRP1,SEMA3A,LRP12,NKX2-1,MEF2C |
| 2.804e-07 | -15.09 | regulation of cellular component organization | biological process | GO:0051128 | 2369 | 297 | 17256 | 1658 |
ATP8A1,LDLR,GATA3,NPM1,SNX9,RAC3,STK24,NCS1,SKI,PMAIP1,RAP2A,TMED9,PACSIN1,TBC1D8,DCC,WISP3,DSTN,TGFA,LRRK2,DNAJC6,BNIP3L,FEZ1,AGO4,GNAI1,ENPP1,WIPF3,NCKAP1L,PLK2,MAP9,ALDOA,ARHGAP28,BBC3,SEMA3C,SERPINI1,TMOD2,ERCC5,INPP5F,TPM1,NRP1,TMEFF2,SPART,MEF2C,EFNB2,CELSR1,PTPRD,TBC1D1,SLK,OPHN1,TJP1,BTBD9,GPSM2,RPL13A,CHN1,MYC,FLRT3,PRELID1,SREBF1,GRIP1,LMAN2,STXBP1,FMNL2,RIMS2,EPB41L5,ENAM,BDNF,MYO10,TBC1D8B,VLDLR,PACSIN3,HIP1,PLS1,SNAP25,PLCB1,FAM162A,PLEKHH2,SH3GL2,PMEPA1,CDH17,DYNC2LI1,LAPTM4B,CDH2,SHTN1,EPHA3,BTC,DNM3,TMSB15A,RHOD,C4A,GPR65,PLXNA2,ADD2,NRXN1,DDR1,TBC1D30,EPB41L3,DACT1,DAB2IP,ZNF365,FZD1,SSH3,MYLK3,FZD4,SHANK2,PREX1,PRKCQ,WNT11,ASPH,TBC1D16,FGFR1,SNCA,DCBLD2,CXCL10,APELA,PAM,KLF5,ATG5,MID1,COBL,STON2,WASF3,ROBO2,IGFBP6,CKAP2,EPS8,BIK,ARL2,GAS6,EPHB1,NEDD4,ADGRB2,LRRN1,SGK3,FIG4,TBC1D9,GFI1,SMAD6,SPRY2,FES,LZTS3,SYNPO2,PXN,RAPGEF2,RACK1,NSD1,FGR,BMP4,SHOX2,OCLN,FGF13,HDGFL3,JCHAIN,LILRB1,RND2,ADPRHL1,ARHGEF10L,TUBB4A,PPM1E,HRK,CTTN,ENO1,TLR4,IL1RAP,NEB,SLIT2,PDGFRB,DBN1,TNK2,GPM6A,SESN2,SGK2,TRIM9,GSN,INSIG1,MAP2,OXTR,PPARGC1A,MAGI2,CHMP4C,UST,PRKAA2,FN1,LGALS3,BVES,RHOBTB1,JDP2,FBXO4,STXBP6,CHADL,SORBS3,PFN2,SPIRE1,FHOD3,KIAA1958,IGF1R,SEMA4F,GATA2,ADCY6,BNIP3,FGFR4,PAK1,ATP5IF1,RHOQ,SLITRK2,SLITRK5,SDK1,BAIAP2,TBC1D2,NEGR1,RIPOR2,ADGRB3,SH3BP4,HK2,PLD1,SEMA3A,FNBP1L,SFN,PRKN,ZSWIM5,ID1,DOCK1,HECW2,NTRK3,CBLN1,DOCK2,PPP1R9A,CTNNA2,TBC1D19,SCIN,CD53,PDZD8,UNC13B,CDC14B,ADGRL1,BCL6,MET,HSPA2,SNAI2,IGFBP3,FER,PHLDB2,TMEM67,EVL,NOP53,VIM,AMIGO1,SYNJ2BP,DOCK5,JAM3,CENPV,C4BPB,WARS,SMAD3,RANBP2,NRG3,PTPRJ,PTK7,GBP1,ITGA2,PTPRS,HGF,CNTN1,TENM1,TNIK,NECAB2,BMPR2,ARHGEF11,LRP4,APBB1,CLSTN2,SLX1B,USP30,ARHGAP44,NKX6-1,FSD1,MAP1A,SCN1B,PRKCD,EHD3,KIAA0319,GTF2F2,SGK1,SH3PXD2B,SYK,DUSP1,MSX1,CRIM1,ASAP3,FERMT2,TLR6,DKK1,MAP1B,MYADM,RND3,MPP7,CTSV,TBC1D4,NPHP1 |
| 2.969e-07 | -15.03 | GO_NEURON_DEVELOPMENT | MSigDB lists | GO_NEURON_DEVELOPMENT | 664 | 106 | 17377 | 1707 |
EPHA3,NBL1,UGT8,CELSR3,KIF5A,RBFOX2,PLXNA2,GATA3,ENAH,NRXN1,RAC3,PPP1R9A,SEMA6A,CTNNA2,EPB41L3,GPRIN1,COL25A1,LHX6,DAB2IP,CTTN,PACSIN1,ETV1,SLIT2,NTNG1,SEMA6C,NKX2-1,ATL1,GPM6A,EVL,DCC,LRRK2,ADCY1,FEZ1,PRKCQ,AMIGO1,ATOH1,JAM3,FGFR1,TSKU,MAP2,LAMB1,SEMA3C,UNC5B,NRP1,LIFR,COBL,CTNND2,CNTN1,MEF2C,BCL11B,EFNB2,LRFN5,FARP1,ROBO2,GABRB2,LRP4,APBB1,OPHN1,KIF5C,SLC1A3,EPHB1,PHGDH,GDPD5,NEDD4,NEO1,CHN1,NUMBL,LRRC55,CNTN4,LRRN1,FRY,SEMA4F,PDZD7,GATA2,SCN1B,FLRT3,PRKG1,SGK1,GRIP1,FIG4,NCAM1,STXBP1,PAK1,DPYSL5,UNC5C,DISC1,BDNF,SLITRK2,RAPGEF2,VLDLR,EFNA3,SLITRK5,PRDM1,CLN5,BAIAP2,RERE,MAP1B,DOCK7,FAT4,THBS4,GNAO1,MATN2,XBP1,CLMN,SEMA3A,NKX2-8 |
| 2.998e-07 | -15.02 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | 195 | 43 | 17377 | 1707 |
AVPI1,ACSL1,LGR4,RNF144A,ST14,TBC1D1,GALNT12,BACE1,BLVRB,ARHGAP22,PPFIBP2,SCD,CTBP2,CEBPA,QPRT,ARHGEF10L,RTN1,FKBP9,CHN2,CA2,KMO,STEAP3,SYK,CYP1B1,FADS1,QSOX1,RHOQ,SMARCD3,NPC2,PALLD,ASPH,PLEKHB1,CEBPB,GSN,FGR,MAP2K6,SLC2A6,RAB31,MAOA,RNF130,NRP1,APBA2,STOM |
| 3.197e-07 | -14.96 | negative regulation of signal transduction | biological process | GO:0009968 | 1284 | 177 | 17256 | 1658 |
ACVR1,DUSP8,LGR4,GATA3,NDRG2,CHAC1,KREMEN1,EYA4,SKI,TGFBR3,ZFYVE28,CHRDL1,CTTN,EPHB6,PTPRE,TLR4,ENO1,SLIT2,PRKACB,PDGFRB,NKX2-1,SESN2,LRRK2,DEPTOR,YAP1,ROR1,PLEKHA1,SESN1,TSKU,ENPP1,INSIG1,SH3RF1,INPP5F,SPRY4,DLX2,NRP1,UNC5B,PPARGC1A,SPART,MAGI2,MLLT3,PRKAA2,TYRO3,RGS16,LATS2,RUNX2,LGALS3,ITGA6,UBASH3B,RASL11B,MECOM,DDIT4,IGF1R,GATA2,MYC,FLRT3,C1QL4,PRELID1,LRP6,BARX1,GPR161,ZNF385A,NOS3,RNF152,HMGCR,PTCH2,FGFR4,MSTN,DUSP9,WWC1,STRADB,SHISA2,PRDM1,HERPUD1,RIPOR2,SH3GL2,PMEPA1,HEYL,SH3BP4,EGFL7,CDH2,EPHA3,PRKN,NBL1,BTC,RASAL2,RGS20,NTRK3,TMEM170B,DDR1,PIBF1,CBLN1,CYP26A1,TLR3,DACT1,CNKSR3,MAGEA3,BCL6,DAB2IP,WWC2,MET,SNAI2,GLI1,CTH,IGFBP3,FZD1,PRAME,NOP53,PTPN6,PREX1,RNF125,NLGN4X,PRKCQ,WNT11,CBY1,GSTO1,ATF3,SYNJ2BP,FGFR1,SNCA,CAMK2N1,SMAD3,PTPRJ,PRKCB,GBP1,RBPMS2,WFS1,WWTR1,MAP3K21,RGS10,DUSP19,PTPRS,HGF,GRB10,HEY1,DYRK3,IGFBP6,C1QTNF3,PAK5,GRB14,LRP4,NOTUM,GAS6,RGS7,EPHB1,GDPD5,ARHGAP44,NEDD4,RGS17,PRKCD,SGK3,YBX3,ERRFI1,SMAD6,SPRY2,DUSP1,GSTM2,LITAF,PRICKLE1,RASA3,RACK1,TLR6,SMPDL3B,DKK1,PTPRC,TRIB3,MYADM,TERT,FBN1,XBP1,MCC,PCGF2,BMP4,DDIT3,BTRC,ATP2B4,TPT1 |
| 3.280e-07 | -14.93 | large_intestine-colon-adenoma | COSMIC cancer mutations | large_intestine-colon-adenoma | 637 | 102 | 17385 | 1698 |
UGT8,PLBD2,FLVCR2,PDE1B,GRIK2,AASS,OTX1,CADM2,FAM13A,KIAA1217,TIAM2,PCDH7,EPB41L3,GPRIN1,UNC13B,SERINC2,JAKMIP2,NEB,KCNB2,SCN3A,RNF145,DCC,SPOCD1,SHANK2,PANK1,PREX1,CR2,NLGN4X,SYNJ2BP,CD40,INTS6,TCERG1L,TTLL7,ASPH,DOCK5,ENPP1,ZNF93,GPRC5B,PDLIM3,MAP2,CCBE1,TECPR2,LAMB1,PTPRS,MAPK13,DSEL,CTNND2,ANKRD13D,STOX2,RUNX2,ROBO2,RHOBTB1,PLAG1,ITGA6,GABRG2,NOTUM,ISYNA1,ZNF219,SFXN3,COL27A1,FHOD3,HSPA12B,NUMBL,NAV1,TECPR1,LRRN1,BCHE,FLRT3,AFF2,EHD3,MPDZ,SLC6A15,LMAN2,DHRS12,PRR16,ZNF518B,SYK,CAND2,IGSF3,MN1,CHSY3,IL17RD,PCDH10,SYNPO2,PTPN13,EDEM3,SMARCD3,GUCY1A2,GPR37,NAP1L5,FAT4,FBN1,ADAMTS3,GNAO1,FAT1,THSD7B,PIP5KL1,DHCR7,KIF1B,XKR4,CRISPLD1,CACNA2D1 |
| 3.283e-07 | -14.93 | ELVIDGE_HYPOXIA_UP | MSigDB lists | ELVIDGE_HYPOXIA_UP | 163 | 38 | 17377 | 1707 |
MXI1,ENO2,ZNF395,SFXN3,FAM13A,PRKCA,DDR1,PGAP1,DDIT4,ALDOC,STC2,OPN3,BNIP3,LIMCH1,MET,IGFBP3,DUSP1,CYP1B1,VEGFC,QSOX1,PDK1,VLDLR,EFNA3,BNIP3L,AK4,ATF3,ASPH,FAM162A,ISG20,P4HA2,SRD5A3,PAM,HK2,AHNAK2,P4HA1,CSRP2,HEY1,RRAGD |
| 3.305e-07 | -14.92 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | 209 | 45 | 17377 | 1707 |
MTG1,DYRK3,ST14,JDP2,NRN1,ZIC2,CHAC1,ABHD4,KBTBD11,SLC19A2,RPL34,DDIT4,FSD1,CPNE2,PMAIP1,RAP2A,STC2,PRELID2,TMEM143,GRIP1,BNIP3,PLTP,ZNF365,PERP,ARAP2,SESN2,PDK1,NR6A1,NPM3,VLDLR,BNIP3L,CCNG1,FAM162A,AK1,PLOD2,PTK7,P4HA2,FAM114A2,FAT1,EIF4EBP1,HK2,P4HA1,RPS12,SUSD4,HOXB9 |
| 3.387e-07 | -14.90 | positive regulation of nervous system development | biological process | GO:0051962 | 488 | 82 | 17256 | 1658 |
EPHA3,PRKN,NBL1,PLXNA2,NTRK3,NRXN1,PPP1R9A,SEMA6A,CBLN1,RND2,BCL6,ADGRL1,DAB2IP,PACSIN1,ZNF488,ZNF365,SLIT2,IL1RAP,GLI1,FZD1,FZD4,SHANK2,FEZ1,AMIGO1,ATOH1,FGFR1,GPRC5B,PTK7,HGF,SERPINI1,OXTR,DLX2,NRP1,MAGI2,COBL,CNTN1,MEF2C,WASF3,FN1,ROBO2,BMPR2,PTPRD,PLAG1,APBB1,CLSTN2,EPHB1,GDPD5,FOXG1,BMP6,ADGRB2,NKX6-1,NUMBL,LRRN1,GATA2,SCN1B,FLRT3,GRIP1,FIG4,FES,RIMS2,PAK1,VEGFC,DISC1,BDNF,SLITRK2,RAPGEF2,VLDLR,SLITRK5,SMARCD3,BAIAP2,DKK1,NEGR1,MAP1B,ADGRB3,CSF1,HEYL,MYRF,BMP4,SHOX2,SEMA3A,FOXA1,SHTN1 |
| 3.390e-07 | -14.90 | GO_RECEPTOR_COMPLEX | MSigDB lists | GO_RECEPTOR_COMPLEX | 321 | 61 | 17377 | 1707 |
GPR63,ACVR1,SORBS1,CACNG3,GRIK2,GABRB2,ITGA6,EPS8,LDLR,PLXNA2,GABRG2,CHUK,IL13RA1,NTRK3,GABRR2,ITPR2,DDR1,ABHD6,NOS1AP,TGFBR3,IGF1R,CHRNA5,GHR,ITGB3,ACVR2A,TRPC1,LRP6,LOXL4,TLR4,TSHR,SYK,ITGB7,ACVR1C,PTPN6,VLDLR,SHANK2,CR2,SLITRK5,CHRNA6,PEX5L,ROR1,ACVR2B,CD40,SKAP1,TLR6,LEPR,FGFR1,GPR37,AHRR,SMAD3,GRIK4,GPR160,ITGA2,TNFRSF1A,PTPRN2,GRIN2D,DLG2,BMPR1A,NRP1,LIFR,NR3C2 |
| 3.424e-07 | -14.89 | nucleoside-triphosphatase regulator activity | molecular function | GO:0060589 | 360 | 66 | 17224 | 1680 |
ARHGAP26,RASAL2,DOCK1,ARHGAP22,RGS20,FAM13A,TBC1D30,DOCK2,TIAM2,TBC1D19,ADPRHL1,BAG3,SIPA1L2,DAB2IP,SLIT2,RASGRP1,TBC1D8,TNK2,SESN2,LRRK2,ELMOD1,PREX1,WNT11,ATP1B1,TBC1D16,RANBP2,ARHGAP21,NCKAP1L,RGS10,ARHGAP28,NRP1,RGS16,STXBP5L,ARHGEF11,TBC1D1,IPO5,OPHN1,ARL2,GPSM2,RGS7,GRPEL2,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,SRGAP1,RALGAPA2,ERRFI1,TBC1D9,ATP5IF1,RIN2,VAV3,ARAP2,TBC1D8B,RAPGEF2,GPSM1,ASAP3,RASA3,AGAP2,ARHGAP32,PLCB1,TBC1D2,ADGRB3,SH3BP4,TBC1D4 |
| 3.439e-07 | -14.88 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN | 85 | 25 | 17377 | 1707 |
CREB3L2,EFNB2,CGN,CD55,ARID5B,PTPN21,YPEL2,GTF2IRD1,GATA3,PSD3,ATP1B1,TNFRSF19,SPATA7,DDIT4,RERE,SMAD3,ENPP1,LAMB1,TUFT1,KLF9,FAM84B,DBP,NRP1,CHRM3,IGSF3 |
| 3.448e-07 | -14.88 | Axon guidance | REACTOME pathways | R-HSA-422475 | 549 | 88 | 10287 | 971 |
EPHA3,BTC,DNM3,RASAL2,DUSP8,DOCK1,PLXNA2,ENAH,PRKCA,CACNB4,SEMA6A,RPS6KA2,ITGB3,TRPC1,DAB2IP,EPHB6,SCN2A,MET,SLIT2,RASGRP1,PRKACB,SCN3A,PDGFRB,GAB2,COL6A2,EVL,COL4A3,DCC,CAP2,ANK2,PRKCQ,FGF17,FGFR1,IRS2,NRG3,RASGRF2,LAMB1,ITGA2,GRB10,HGF,UNC5B,NRP1,CNTN1,EFNB2,COL9A3,SCN5A,ROBO2,FN1,ARHGEF11,PAK5,SCN8A,COL4A5,EPHB1,PFN2,DOK5,NEO1,ABLIM1,SCN1B,CACNB2,SRGAP1,NCAM1,GFRA1,COL9A2,FES,DUSP1,FGFR4,PAK1,DPYSL5,PDLIM7,IL17RD,UNC5C,VAV3,ARHGEF28,KCNQ3,MYO10,RAPGEF2,COL4A4,EFNA3,DUSP9,RASA3,AGAP2,PTPRC,SH3GL2,GRIN2D,SPRED3,TRPC3,SEMA3A,SHTN1 |
| 3.485e-07 | -14.87 | PACHER_TARGETS_OF_IGF1_AND_IGF2_UP | MSigDB lists | PACHER_TARGETS_OF_IGF1_AND_IGF2_UP | 35 | 15 | 17377 | 1707 |
NELL2,SLC3A2,SESN2,ASNS,SLC7A11,SEC24D,SLC7A5,INHBE,ASS1,PHGDH,MID1,PSPH,DDIT3,HERPUD1,MAP1B |
| 3.588e-07 | -14.84 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | 183 | 41 | 17377 | 1707 |
GPT2,MOCOS,MXI1,FGF13,HEBP1,ST6GAL1,LRP4,UGDH,PTPN21,YPEL2,CEBPA,SLC36A4,GAS6,FAM110B,RAB11FIP5,FBXO32,ZNF438,CNKSR3,GPR155,SLC10A7,TMEM86A,RAP2A,WWC2,RCAN3,SPRY2,GATM,GAB2,SLC40A1,SLC3A2,MAFB,SDC3,NPC2,TBC1D2,HK2,KIAA0513,DBP,TTC39A,HEY1,RRAGD,ABCG1,CRYL1 |
| 3.588e-07 | -14.84 | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN | 183 | 41 | 17377 | 1707 |
RGS16,ACSL1,SCAMP1,CFH,CYP4V2,KCTD12,GABRR2,KIAA1217,CANX,PCLO,DDIT4,EPCAM,IGF1R,EOMES,SLC7A11,KCNAB1,GATA2,GSTM3,TRPC1,COL19A1,MYO6,PHLDB2,RIN2,GDAP1,MSX1,PNRC1,WLS,YAP1,GSTO1,PLEKHA1,FRK,GPLD1,DOCK7,PTPRJ,MAP2,CSF1,GNAO1,WFS1,RGS10,ERCC5,ABCG1 |
| 3.588e-07 | -14.84 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN | 183 | 41 | 17377 | 1707 |
EXPH5,CARS,IGFBP6,PSTPIP2,GTF2IRD1,RNF24,SPATS2L,PHGDH,AARS,F3,RPS6KA2,ASNS,TSC22D1,LMAN2,CTTN,PCK2,CKAP4,FZD1,ALDH2,LRRC8B,TMEM43,EXOC6B,DCHS1,NFE2L1,ATF3,SAV1,DSP,EML1,WARS,CEBPB,TRIM9,NACC2,GBP1,CCNA1,INHBE,KIAA0513,SERPINI1,INPP5F,SLC1A5,CTNND2,MAST1 |
| 3.602e-07 | -14.84 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_DN | 170 | 39 | 17377 | 1707 |
PLAG1,PSD3,KCTD12,IGF2BP2,SORBS3,SLC1A3,FAM110B,FKBP11,TRPS1,MGAT1,KAZN,LHX6,GULP1,SERPINH1,PRR16,TSPAN9,ZFP36L2,OPLAH,PRAME,GSTM2,FZD4,PTPN13,WLS,ASAP3,WNT11,STEAP1,ZIC1,TSKU,SLC39A14,FAT4,PLK2,EIF4EBP1,BMP1,RGS10,INPP4B,TNFRSF1A,BMP4,SLC1A5,HEY1 |
| 3.643e-07 | -14.83 | AGC_KINASE_CTER | prosite domains | PS51285 | 55 | 20 | 12060 | 1278 |
LATS2,PRKCQ,GRK6,CDC42BPA,SGK2,PKN1,PRKCA,GRK3,RPS6KA2,PKN3,PRKCB,AKT3,PRKCD,PRKG1,SGK3,SGK1,PRKG2,MAST4,PRKACB,MAST1 |
| 3.691e-07 | -14.81 | positive regulation of biological process | biological process | GO:0048518 | 5677 | 637 | 17256 | 1658 |
THOC5,GRIK2,DNAJC3,LSM11,NPM1,CTBP2,STAT5B,CEBPA,NHP2,SNX9,ABHD6,EYA4,NOS1AP,SKI,BAG3,TGFBR3,PMAIP1,RAP2A,TMED9,TSHR,POU3F3,NKX2-1,MEIS2,SMAD9,WLS,DSTN,TGFA,LRRK2,NFIA,FEZ1,PRKAR2B,FGF17,F12,WIPF3,ADRB1,BBC3,ZBTB20,TMOD2,ERCC5,DIRAS1,INPP5F,TPM1,VASH2,MEF2C,SCN5A,LATS2,ITGA6,SLK,GPSM2,FOXG1,CHN1,APLF,CACNB2,FLRT3,LMAN2,TOX,CADPS2,ST8SIA1,GLIS1,STXBP1,CHRM3,ZNF385A,HMGCR,ENAM,BDNF,PNP,MYO10,STAT4,ARID5B,FHL2,FASN,RYR2,HIP1,CALCRL,SMARCD3,PLS1,C1R,SNAP25,ARRDC4,TAF4B,SH3GL2,ADAMTS3,CDH17,INHBE,HOXD13,CDH2,TRPC3,SHTN1,TFCP2L1,BTC,DNM3,ZNF516,C4A,PKP2,COLEC10,NRXN1,LCP2,TLR3,KMO,DACT1,CNKSR3,RTKN2,SYNGR3,RAB27B,ZNF365,PERP,DOCK8,FZD1,MYLK3,GAPDH,ADM2,FZD4,PFKFB2,ADCY1,WNT11,PXYLP1,ASPH,FGFR1,IRS2,CXCL10,GYPC,WFS1,PEMT,APELA,WWTR1,LAMB1,TNFSF15,DBP,HOXB9,C1QTNF3,EDA2R,ROBO2,CKAP2,PLAG1,FZD8,CD276,IPO5,BIK,GAS6,P2RY1,CREB5,PKN1,EPHB1,ZNF219,TSPAN17,NEO1,LRRN1,PCBP4,MCF2L,BHLHA15,GHR,MYO6,ZFP36L2,FES,MED12L,PARP9,PDLIM7,TRPM4,VEGFC,RAPGEF2,GAREM1,RACK1,HEG1,PTPRC,TRIB3,ID3,NSD1,AKT3,XBP1,BMP4,SHOX2,ATP2B4,FOXA1,BTRC,CACNG3,FGF13,TRIM16,SYT12,LMCD1,LILRB1,ASS1,RND2,RPS6KA2,TCAF2,EOMES,SEC16B,ITGB3,ETV1,TLR4,ENO1,CD55,ATF4,GCNT2,COL4A3,ANK2,NFE2L1,CR2,PLEKHA1,BATF,SESN1,DYRK1B,INHBC,INSIG1,ERN1,TNFRSF1A,DLX2,NEUROG2,CACUL1,MLLT3,RRAGD,CHMP4C,PRKAA2,LONRF1,TYRO3,RUNX2,STXBP5L,LGALS3,SORBS3,ZIC2,PFN2,MLC1,IL18R1,SPIRE1,RNF180,NUMBL,ZBTB38,SEMA4F,IGF1R,GATA2,LRP6,ADCY6,BNIP3,PAK1,FGFR4,UNC5C,MID2,BTNL9,EFNA3,GPSM1,SLITRK5,STRADB,MAFB,OBSCN,PDE8A,BAIAP2,NEGR1,MAPKAPK2,HEYL,CSF1,SEMA3A,TESC,SIX2,SFN,PRKN,ID1,AVPI1,CFH,AKAP5,DOCK1,NTRK3,LPIN3,TNKS1BP1,PPP1R9A,SEMA6A,CBLN1,CTNNA2,BCL6,ADGRL1,ZNF488,SNAI2,GLI1,IGFBP3,CTH,INTU,EVL,NOP53,FGF12,RNF125,VIM,GSTO1,RARRES2,C4BPB,SMAD3,RANBP2,NRG3,PTPRJ,RNF217,PTK7,ITGA2,HGF,SUSD4,CNTN1,HEY1,TENM1,NECAB2,BMPR2,GRB14,PAK5,APBB1,FOXP2,MAP1A,RASD2,GTF2F2,TFAP2A,SGK1,SH3PXD2B,PCK2,SYK,SLC45A3,DUSP1,MOB1B,MICAL2,FOXN3,CRIP2,LITAF,PRICKLE1,MGMT,MAP10,DKK1,EBF1,DDAH1,DOCK7,MYRF,PAX9,KIF1B,CACNA2D1,ACVR1,LGR4,ATP8A1,LDLR,VAMP8,GATA3,PRKCA,RAC3,STK24,NCS1,TRPS1,FAM168A,CFHR1,PACSIN1,PLTP,TBC1D8,NR6A1,ACVR1C,BNIP3L,MEF2B,ACVR2B,SAV1,ARHGEF26,GNAI1,AHRR,HLF,NCKAP1L,CCBE1,RASGRF2,PLK2,BMP1,SERPINI1,MAPK13,SEMA3C,UNC5B,NRP1,EFNB2,ZHX3,PTPRD,SLC25A27,SLC1A3,TNFRSF10C,TNFRSF19,CHD5,MYORG,MECOM,MCOLN2,IL17D,PIK3AP1,MYC,PRELID1,SREBF1,GRIP1,PRR16,GPR161,RIMS2,RNF152,EPB41L5,PTCH2,RPL26,DISC1,VLDLR,PACSIN3,NSD2,PLCB1,FAM162A,PELI2,THBS4,MPP2,SMYD3,EPHA3,NBL1,AMOTL1,RNF144A,RHOD,GPR65,PLXNA2,MSR1,OTX1,CHUK,DDR1,TIAM2,ASNS,STARD4,SHF,DAB2IP,PDE4D,GAB2,SOX21,SHANK2,PREX1,PRKCQ,SATB2,ATF3,ATOH1,PYGO1,ATP1B1,SNCA,ZNF711,IKZF3,BEX3,PRKCB,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,ATG5,MAPK10,COBL,MID1,WASF3,EPS8,ARL2,NDFIP2,GDPD5,TPD52L1,ADGRB2,NEDD4,GSAP,KDM7A,LRRC55,SGK3,FIG4,DYNC2H1,YBX3,SMAD6,GFI1,SPRY2,PFKFB4,VAV3,SLC40A1,SYNPO2,SH3BP2,GSTM2,PXN,GUCY1A2,SKAP1,HOXA1,ZIC1,GPLD1,CEBPB,FGR,TERT,SVIL,GRIN2D,LRRK1,LARP1,DDIT3,EXPH5,ACSL1,JCHAIN,ABAT,IKZF2,GSDME,F3,EPCAM,ARHGEF10L,PPM1E,GRHL1,ABI3BP,DLX6,TRPC1,HRK,EPHB6,PCOLCE2,CTTN,FANK1,MYRIP,IL1RAP,SLIT2,RASGRP1,PDGFRB,PRKACB,LAMP3,CYP1B1,TNK2,GPM6A,SESN2,SKAP2,YAP1,ROR1,SGK2,GSN,GPRC5B,HPSE,NCOA7,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,BCL11B,FN1,BVES,JDP2,FBXO4,CHSY1,DDIT4,EEF2,CA2,EBF4,INAVA,BARX1,CEBPD,CAND2,NOS3,RAX,ATP5IF1,RHOQ,SLITRK2,MSTN,SH2D2A,WWC1,DUSP9,PRDM1,HERPUD1,RIPOR2,PLAGL1,ADGRB3,SH3BP4,HK2,EGFL7,NKX2-8,FNBP1L,CREB3L2,CXCR5,NEK10,SORBS1,IL15,COL18A1,HECW2,PIBF1,DOCK2,SCIN,CD53,UNC13B,CDC14B,ACVR2A,MET,POU2F2,HSPA2,ALG10B,DPP10,PRAME,PHLDB2,FER,MVD,PTPN6,AMIGO1,CD40,DOCK5,CENPV,WARS,CAMK2N1,TRIM34,RBPMS2,EIF4EBP1,DUSP19,SOHLH2,DISP1,LIFR,TNIK,ARHGEF11,REL,LRP4,TNFSF13B,CLSTN2,SLX1B,OVOL2,BMP6,MCU,NKX6-1,CHN2,SCN1B,PRKCD,EHD3,ACTA2,AFAP1L2,IQGAP3,RRAS2,TNFRSF11A,TESPA1,PNMA2,USP2,RAB3B,MSX1,KDM5B,HNF4G,ESRRG,NR4A1,CYTH3,SYBU,MARS,AGAP2,ZFPM2,TLR6,LRAT,RERE,MAP1B,GPR37,MYADM,EDA,MPP7,NACC2,ACER2,MAP2K6,NPHP1,MAP3K20,ABCG1,STOM |
| 3.748e-07 | -14.80 | breast | COSMIC cancer mutations | breast | 16905 | 1680 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,SLX1B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,LRRCC1,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 3.824e-07 | -14.78 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_UP | 190 | 42 | 17377 | 1707 |
CARS,GPT2,ZNF516,SLC6A9,JDP2,TNFAIP8L2,CHAC1,PHGDH,AARS,DDIT4,ATXN7L1,ASNS,PDZD8,FAM84B,PCK2,MORN4,LRP3,RASGRP1,ATF4,SESN2,SLC3A2,PNRC1,SLC37A1,NFE2L1,FERMT2,ATF3,ATP11A,FNDC3A,MFSD6,BATF,HERPUD1,PYCR1,CEBPB,SLC7A1,TRIB3,CLDN12,EIF4EBP1,SLC7A5,ZNF808,TTC39A,PSPH,DDIT3 |
| 4.082e-07 | -14.71 | endometrium | COSMIC cancer mutations | endometrium | 16181 | 1627 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,RAB38,TTC28,METAP1D,FGFR1,IQCK,IQCH,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,RBM11,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 4.087e-07 | -14.71 | intrinsic component of plasma membrane | cellular component | GO:0031226 | 1733 | 224 | 18223 | 1724 |
ACVR1,CACNG3,LGR4,GRIK2,LDLR,CADM2,SLC2A13,ABHD6,SLCO3A1,NOS1AP,PCDH7,F3,EPCAM,TGFBR3,TM9SF2,KCNAB1,HPS1,SLC16A2,ITGB3,RAB26,KCNS3,TRPC1,SLC2A12,CTTN,EPHB6,TLR4,TSHR,IL1RAP,PDGFRB,ITGB7,CD55,KCNIP3,ABCC4,CEMIP2,ACVR1C,TGFA,LRMP,PLPP2,ABCC2,ACVR2B,KCND3,ROR1,GPC6,SLC7A1,ENPP1,TMEM150B,KCNMB4,NCKAP1L,ATP7B,TNFRSF1A,ADRB1,OXTR,TNFSF4,TYRO3,EFNB2,KCNV1,SEMA6B,SCN5A,MRC2,CELSR1,PTPRD,GABRB2,SCN8A,ITGA6,SLC1A3,TNFRSF10C,GAS1,PCDHB14,IGF1R,SEMA4F,SLC7A11,CACNB2,FLRT3,OPN3,ADCY6,TSPAN12,LMAN2,SLC16A9,SLCO4C1,JAM2,TSPAN9,LRP12,CHRM3,FGFR4,IL17RD,GPR176,PCDH10,PODXL2,KCNQ3,EFNA3,CALCRL,SNAP25,OR11H4,GPR19,STEAP1,MMP15,GRIK4,KCNK15,MFSD2A,FAT1,SLC2A6,MPP2,PTPRN2,CDH2,TRPC3,MME,CXCR5,EPHA3,SORBS1,RASAL2,IL15,ST14,GPR65,PLXNA2,MSR1,NTRK3,IL13RA1,CHUK,SLC7A2,NRXN1,DDR1,SEMA6A,CD53,GPR15,PLPP1,TLR3,SLC22A17,CHRNA5,COL25A1,ACVR2A,DAB2IP,STEAP3,SCN2A,MET,NTNG1,PERP,SEMA6C,KCNB2,SCN3A,DPP10,PTPRU,FZD4,KCNH5,SLC39A8,SHANK2,ADCY1,NLGN4X,CHRNA6,AMIGO1,ATP1B1,CD40,FGFR1,DCBLD2,HTR7,ENTPD1,SLC39A14,NRG3,PTPRJ,GYPC,PTK7,TMPRSS9,KCNG1,ITGA2,ASIC1,MAP3K21,PTPRS,TNFSF15,HS3ST3B1,LIFR,TENM1,PCDH18,LPAR2,SLC6A9,BMPR2,EDA2R,TSPAN15,BACE1,SELL,GABRG2,GABRR2,SLC12A6,P2RY1,EPHB1,SLC35G2,KCNC4,TSPAN17,NEO1,LRRC55,KCNJ4,SCN1B,GHR,KCNMB3,TSPAN13,SLC6A15,TNFRSF11A,ATP2B1,ULBP1,TRPM4,SLC40A1,RAPGEF2,MPP1,PRRG1,RASA3,TLR6,GPR37,PTPRC,CD37,EDA,PCDHB7,PLPPR2,SLC7A5,SLCO5A1,SLC18B1,GRIN2D,DLG2,SLC22A15,SLC1A5,IL9R,MMP16,SLC16A10,ATP2B4,ATP1A3,SLC43A1,STOM |
| 4.091e-07 | -14.71 | GO_ACTIN_BINDING | MSigDB lists | GO_ACTIN_BINDING | 374 | 68 | 17377 | 1707 |
PHACTR3,CGN,SORBS1,AKAP5,PSTPIP2,MYO1B,ADD2,COBLL1,ENAH,PPP1R9A,CTNNA2,SCIN,PLS3,EPB41L3,MYO3B,POF1B,MYH15,MARCKS,TLN2,MYRIP,NEB,DBN1,SSH3,EVL,KLHL3,KLHL4,CAP2,DSTN,LRRK2,TNS1,COTL1,GSN,WIPF3,GBP1,ALDOA,TMOD2,TPM1,COBL,MYO1D,WASF3,INPPL1,EPS8,OPHN1,PFN2,ADSSL1,FHOD3,SPIRE1,ABLIM1,EEF2,MAP1A,CACNB2,GAS2L3,SMTN,LIMCH1,MYO6,FMNL2,NOS3,MICAL2,SYNPO2,MYO10,HIP1,PHACTR2,PLS1,SNTB1,PALLD,PLEKHH2,CLMN,SVIL |
| 4.257e-07 | -14.67 | regulation of actin cytoskeleton organization | biological process | GO:0032956 | 330 | 61 | 17256 | 1658 |
EPHA3,TENM1,PRKN,ID1,CELSR1,TMSB15A,RHOBTB1,RHOD,GPR65,EPS8,ADD2,SORBS3,NTRK3,PFN2,RAC3,PPP1R9A,ARHGAP44,FHOD3,SPIRE1,SCIN,RND2,ARHGEF10L,PPM1E,PRKCD,CTTN,SH3PXD2B,MET,SLIT2,NEB,FES,PDGFRB,PAK1,FER,PHLDB2,SSH3,SYNPO2,EVL,PXN,MYLK3,RHOQ,DSTN,ASAP3,PREX1,WNT11,JAM3,BAIAP2,SMAD3,GSN,PLEKHH2,MYADM,RND3,WIPF3,NCKAP1L,CTSV,PAM,ARHGAP28,TMOD2,TPM1,TMEFF2,NRP1,MEF2C |
| 4.286e-07 | -14.66 | oesophagus-middle_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-middle_third-carcinoma-squamous_cell_carcinoma | 3620 | 434 | 17385 | 1698 |
DOC2A,MYCBP2,ADAL,TCP11L2,SIDT1,PRSS12,RECK,LDLR,MCOLN3,GATA3,TUBE1,KIAA1217,CA8,AARS,RAC3,DACH2,EYA4,STK24,HECTD2,TXNDC5,FBXO32,TGFBR3,SLC16A2,PPFIA2,CFHR1,KCNS3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,POU3F3,TBC1D8,SMAD9,KLHL23,WISP3,KLHL4,GJB2,LRRK2,SLC25A28,ABCC2,F12,CA13,GPC6,GPR150,SPATA9,ZNF266,ATP7B,ENTPD7,SEMA3C,ZBTB20,UNC5B,LZTS1,MEF2C,SEMA6B,LRFN5,SCN5A,TMEM63C,LATS2,CELSR1,EHHADH,ZHX3,SCN8A,ITGA6,DHCR24,TJP1,GPSM2,APBA1,DYNC1I1,MECOM,SYCP2,ABLIM1,NAV1,FRY,KIAA1671,C1QL4,VWDE,RUNDC3B,SRGAP1,OPN3,SLC16A9,MPDZ,TOX,CADPS2,DENND1C,FIGN,MOXD1,FAM155A,FMNL2,LRP12,RIMS2,EPB41L5,TBC1D8B,MYO10,PLEKHA8,COL4A4,STAT4,ARID5B,DCHS1,ZNF605,FASN,RYR2,TTC30A,HIP1,DAGLA,BEX4,XKR9,TEX15,VPS37D,SH3GL2,ADAMTS3,LRRIQ3,MATN2,MPP2,SQLE,SLFN5,MTG1,FRMPD3,EPHA3,AMOTL1,ZNF516,TCTN2,RASAL2,CCDC110,MYO1B,PLXNA2,COL14A1,TBC1D30,TIAM2,TXNRD3,NELL2,EPB41L3,ZNF827,ZNF438,KMO,COL25A1,ALDOC,NBEA,DAB2IP,PDE4D,FAM155B,JAKMIP3,DNAH5,MYT1,SCN3A,DOCK8,DZANK1,VNN2,GARS,COL6A2,RNF145,KCNH5,SHANK2,TRAM1L1,ADCY1,NLGN4X,ATF3,DSP,ASPH,MAGI3,IQCH,WFS1,INPP4B,ZNF704,PLD5,NR3C2,HACE1,DENND5B,MYO1D,FARP1,TMEM132C,WDR17,EPS8,CBS,CREB5,PKN1,EPHB1,ZNF219,TSPAN17,NEO1,MGAT1,AFF2,GAS2L3,RALGAPA2,DYNC2H1,SMPDL3A,MED12L,B4GALT6,TRPM4,MN1,VAV3,ARHGEF28,SYNPO2,SH3BP2,ARAP2,CACNA1E,MCF2L2,PTPN13,RASA3,HOXA1,ZIC1,GALNT3,PTPRC,TRIB3,NSD1,PLOD2,PLPPR2,GNAO1,XBP1,SLCO5A1,SVIL,NEK11,DOCK6,ATP2B4,EXPH5,FGF13,KIF5A,LILRB1,FAM13A,HMCN1,FSTL5,CHST10,CEP85L,RTN1,LGI2,FKBP9,RUFY4,RPS6KA2,KCNN2,HPS1,ABI3BP,MARVELD2,TMEM143,TRPC1,JAKMIP2,KIAA1614,SLC2A12,PCOLCE2,TLN2,PTPRE,MYRIP,TLR4,OR2W3,NEB,SLIT2,ZNF391,GPM6A,SLC3A2,SESN2,COL4A3,ANK2,ZNF565,TMEM200C,CR2,TCERG1L,SESN1,NT5DC2,TRIM9,GSN,KLF12,TECPR2,ERN1,TNFRSF1A,MAGI2,TC2N,HS6ST3,CHMP4C,PCSK5,SV2B,MOCOS,FN1,OTOGL,ELOVL7,SETBP1,CHADL,CHSY1,PFN2,MLC1,CD7,FHOD3,KIAA1958,CA2,SLC30A4,ABCA5,FRAS1,SAMD11,GAN,HS3ST5,FAM107B,ADCY6,SLCO4C1,RNF148,NCEH1,LRP3,CHSY3,IL17RD,UNC5C,PCDH10,SLITRK2,SLC27A2,MSTN,HOMER2,MGAT4B,TMTC4,SPATA13,OBSCN,SLITRK5,WWC1,PRDM1,KHDRBS2,GPR19,GRIK4,PLAGL1,FAT1,PTPRN2,FBRSL1,SEMA3A,XKR4,CXCR5,DMXL2,EML5,NEK10,CFH,AKAP5,CELSR3,PSTPIP2,LPCAT2,PLEKHA5,XYLT1,MORC4,COL18A1,COBLL1,NTRK3,FAM198B,SEZ6L2,LPIN3,DENND3,KBTBD11,TNKS1BP1,RADIL,DOCK2,PCLO,SP8,CYP26A1,SCIN,FAM131B,ZNF362,COL22A1,TACC2,PPFIBP1,LHX6,ZNF521,BCL6,MAP7,MYH15,WWC2,MET,SCN2A,ALG10B,GLI1,SUSD3,DPP10,EVL,CSN2,TDRD3,PRDM13,C3orf52,CD40,DOCK5,FRK,JAM3,TPK1,WARS,RANBP2,NRG3,PTPRJ,TMPRSS9,ITGA2,PTPRS,HGF,CYP2U1,ZNF701,C8orf48,CTNND2,PSPH,MAN2B2,TNIK,PCDH18,ARHGEF11,TSPAN15,RUSC2,APBB1,LRP4,CLSTN2,SELL,RASD1,IGF2BP2,SEL1L3,ARHGAP44,FOXP2,FSD1,MAP1A,DSG2,TSC22D1,KIAA0319,MARCH3,SGK1,KIAA0408,DLGAP1,RIN2,CARD6,HNF4G,FOXN3,SYBU,OGDHL,MEI1,PRICKLE1,NPDC1,SMPDL3B,HOMER3,RERE,GPR37,ICA1,DOCK7,MYADM,FBN1,L3MBTL4,THSD7B,SH3BGRL2,DLG2,KIF21A,TBC1D4,FILIP1,SLC16A10 |
| 4.348e-07 | -14.65 | enzyme linked receptor protein signaling pathway | biological process | GO:0007167 | 725 | 111 | 17256 | 1658 |
EPHA3,CGN,BTC,SORBS1,ID1,ACVR1,DOCK1,RBFOX2,NTRK3,STAT5B,LCP2,PRKCA,DDR1,ZFYVE9,SKI,TGFBR3,ITGB3,CHRDL1,ACVR2A,DAB2IP,EPHB6,MET,PDGFRB,GAB2,TNK2,FER,GCNT2,COL4A3,SMAD9,PTPRU,ACVR1C,TGFA,FGF12,VIM,FGF17,ACVR2B,PLEKHA1,ROR1,FRK,FGFR1,SMAD3,IRS2,INHBC,NRG3,PTPRJ,NCKAP1L,EIF4EBP1,APELA,HPGD,MAPK13,HGF,GRB10,BMPR1A,NRP1,MAGI2,LIFR,EFNB2,RUNX2,BMPR2,PTPRD,UBASH3B,ESRP1,LRP4,EPS8,ATP6V1E2,COL4A5,GAS6,EPHB1,CD7,DOK5,BMP6,DDIT4,EFEMP1,CHN1,IGF1R,FLRT3,GHR,SREBF1,GTF2F2,SMAD6,SYK,GFRA1,FES,VEGFC,PAK1,FGFR4,BDNF,VAV3,MSX1,RHOQ,ARHGEF28,PXN,MSTN,SH2D2A,CRIM1,RAPGEF2,ARID5B,EFNA3,FERMT2,RYR2,GAREM1,PLCB1,BAIAP2,GPLD1,GALNT3,MAPKAPK2,FGR,FAT4,CSF1,INHBE,BMP4 |
| 4.435e-07 | -14.63 | regulation of response to stimulus | biological process | GO:0048583 | 4159 | 483 | 17256 | 1658 |
ARHGAP26,THOC5,ACVR1,DUSP8,LGR4,GRIK2,DNAJC3,LDLR,VAMP8,GATA3,NPM1,CTBP2,STAT5B,CHAC1,PRKCA,ABHD6,RAC3,EYA4,STK24,NOS1AP,SKI,BAG3,TYMP,FBXO32,TGFBR3,PMAIP1,ZFYVE28,CFHR1,FAM168A,RAP2A,CHRDL1,RCAN3,NKX2-1,WISP3,WLS,TGFA,LRRK2,DEPTOR,ACVR2B,FGF17,F12,GPC6,ARHGEF26,GNAI1,PYCR1,ENPP1,WIPF3,SH3RF1,NCKAP1L,CCBE1,RASGRF2,PLK2,ADRB1,BMP1,ARHGAP28,BBC3,SEMA3C,MAPK13,TMOD2,DIRAS1,INPP5F,SPRY4,NRP1,UNC5B,SPART,MEF2C,EFNB2,SCN5A,LATS2,ITGA6,OPHN1,GTF2IRD1,TNFRSF10C,TNFRSF19,CHD5,GAS1,MYORG,MECOM,MTUS1,IL17D,CHN1,RALGPS2,PIK3AP1,APLF,MYC,FLRT3,C1QL4,PRELID1,SRGAP1,PRKG1,FIGN,STXBP1,RIMS2,ZNF385A,GPR161,RNF152,HMGCR,PTCH2,RPL26,BDNF,DISC1,MYO10,NSD2,HIP1,CALCRL,C1R,PEX5L,SHISA2,TAF4B,PLCB1,FAM162A,TEX15,SH3GL2,PMEPA1,ADAMTS3,PELI2,THBS4,INHBE,SPRED3,IQSEC2,CDH2,TRPC3,EPHA3,NBL1,BTC,RASAL2,RHOD,C4A,GPR65,RGS20,PLXNA2,CHUK,GRK6,TMEM170B,COLEC10,NRXN1,LCP2,DDR1,TIAM2,TLR3,DACT1,CNKSR3,MAGEA3,SHF,DAB2IP,PDE4D,ZNF365,FZD1,GAB2,ADM2,FZD4,SHANK2,PREX1,NLGN4X,ATF3,CBY1,WNT11,PRKCQ,FGFR1,MAGI3,SNCA,IRS2,CXCL10,ARHGAP21,GYPC,PRKCB,WFS1,APELA,WWTR1,PLEKHG1,MAP3K21,TNFSF15,GRB10,BMPR1A,ATG5,MAPK10,MID1,CGB2,FARP1,C1QTNF3,EDA2R,ROBO2,IGFBP6,FZD8,CD276,EPS8,BIK,UBAC2,PSD3,HERC5,GAS6,P2RY1,PKN1,EPHB1,RGS7,NDFIP2,GDPD5,TPD52L1,TSPAN17,PHLDA2,NEDD4,NEO1,RGS17,MCF2L,GHR,SGK3,RALGAPA2,DYNC2H1,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,FES,PARP9,ULBP1,TRPM4,VEGFC,VAV3,SH3BP2,PXN,ARAP2,ARHGEF28,GSTM2,PTPN13,MPP1,MCF2L2,RAPGEF2,RASA3,GAREM1,RACK1,SKAP1,ZIC1,GPLD1,PTPRC,TRIB3,FGR,TERT,AKT3,XBP1,MCC,PCGF2,BMP4,LRRK1,SHOX2,DDIT3,ATP2B4,FOXA1,BTRC,TPT1,MVK,CACNG3,FGF13,TRIM16,TNFAIP8L2,LMCD1,NDRG2,HDGFL3,LILRB1,ABAT,FAM13A,KREMEN1,F3,GSDME,ARHGEF10L,SIPA1L2,AKAP7,ITGB3,HRK,EPHB6,CTTN,PTPRE,ENO1,TLR4,SLIT2,PRKACB,PDGFRB,RASGRP1,CYP1B1,ITGB7,CD55,ATF4,GCNT2,SESN2,SKAP2,JPH1,YAP1,CR2,ROR1,PLEKHA1,SESN1,TSKU,INHBC,GSN,TCF7L1,GPRC5B,HPSE,INSIG1,ERN1,NCOA7,TNFRSF1A,DLX2,PPARGC1A,TNFSF4,MAGI2,MLLT3,RRAGD,PRKAA2,TYRO3,RGS16,RUNX2,FN1,LGALS3,RHOBTB1,FBXO4,UBASH3B,RASL11B,SORBS3,CHSY1,SPINK5,MLC1,IL18R1,DOK5,DDIT4,EFEMP1,SEMA4F,IGF1R,GATA2,PDE10A,LRP6,INAVA,BNIP3,FBXL2,BARX1,NOS3,PAK1,FGFR4,ATP5IF1,MID2,RHOQ,MSTN,BTNL9,SH2D2A,HOMER2,SPATA13,WWC1,STRADB,OBSCN,DUSP9,PDE8A,PRDM1,HERPUD1,BAIAP2,MAPKAPK2,RIPOR2,CSF1,HEYL,NCR3LG1,SH3BP4,EGFL7,SEMA3A,SFN,PRKN,SORBS1,ID1,ZSWIM5,NEK10,AVPI1,CFH,AKAP5,DOCK1,IL15,ARHGAP22,NTRK3,BCL6B,SLC7A2,PIBF1,CBLN1,CTNNA2,CYP26A1,UNC13B,BCL6,ACVR2A,PROS1,WWC2,MET,SNAI2,GLI1,CTH,IGFBP3,INTU,FER,PHLDB2,PRAME,NOP53,PTPN6,FGF12,RNF125,CHRNA6,GSTO1,SYNJ2BP,RARRES2,CD40,JAM3,C4BPB,CAMK2N1,SMAD3,RANBP2,NRG3,PTPRJ,GBP1,RBPMS2,ITGA2,RGS10,DUSP19,PTPRS,HGF,DISP1,SUSD4,LIFR,CTNND2,ARFGEF3,HEY1,TENM1,TNIK,DYRK3,NECAB2,IL32,BMPR2,TSPAN15,GRB14,PAK5,ARHGEF11,REL,APBB1,LRP4,CMTM8,NLRP14,TNFSF13B,SELL,NOTUM,CUEDC2,BMP6,ARHGAP44,SYDE2,CHN2,PRKCD,STC2,RASD2,AFAP1L2,IQGAP3,TNFRSF11A,TESPA1,SYK,PCSK6,DUSP1,MSX1,RAB3B,CYTH3,SYBU,LITAF,ASAP3,PRICKLE1,AGAP2,ARHGAP32,TLR6,NPDC1,MGMT,SMPDL3B,DKK1,GPR37,DDAH1,MYADM,TMEM237,EDA,NACC2,GCSAM,MPP7,FBN1,PRCP,MAP2K6,UACA,MAP3K20 |
| 4.443e-07 | -14.63 | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN | MSigDB lists | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN | 191 | 42 | 17377 | 1707 |
LPAR2,AKAP5,PTPN21,IGF2BP2,LACC1,FOXG1,NEO1,TXNRD3,LGI2,EPCAM,EFEMP1,CPNE2,CNKSR3,REEP1,TRPC1,AFAP1L2,SH3PXD2B,IQGAP3,STXBP1,TSPAN9,ZNF518B,SYK,C15orf41,CKAP4,PDGFRB,ERGIC1,BTNL9,PTPN13,PHACTR2,RAB38,ZDHHC14,HOXA1,SLC39A14,CACHD1,PLAGL1,TERT,PLK2,MAP9,PLEKHG1,ADRB1,KIF1B,MID1 |
| 4.459e-07 | -14.62 | skin | COSMIC cancer mutations | skin | 16759 | 1670 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 4.479e-07 | -14.62 | regulation of cell development | biological process | GO:0060284 | 859 | 127 | 17256 | 1658 |
EPHA3,PRKN,NBL1,DNM3,ID1,ZSWIM5,FGF13,DOCK1,LDLR,PLXNA2,HECW2,LILRB1,GATA3,NTRK3,RAC3,PPP1R9A,SEMA6A,STK24,NCS1,SKI,RND2,EOMES,RAP2A,BCL6,DAB2IP,CTTN,PACSIN1,ZNF488,ZNF365,SLIT2,IL1RAP,FZD1,DBN1,SSH3,MYLK3,DCC,FZD4,SHANK2,LRRK2,PREX1,YAP1,FEZ1,VIM,AMIGO1,ATOH1,DOCK5,FGFR1,NRG3,GPRC5B,MAP2,PLK2,GBP1,PTK7,TNFRSF1A,PTPRS,HGF,SEMA3C,SERPINI1,INPP5F,BMPR1A,DLX2,NRP1,SPART,MAGI2,COBL,CNTN1,MEF2C,BCL11B,EFNB2,UST,TNIK,FN1,BMPR2,ROBO2,PTPRD,PLAG1,APBB1,LRP4,GDPD5,FOXG1,BMP6,NEDD4,ARHGAP44,NKX6-1,CHN1,NUMBL,SEMA4F,CNTN4,SCN1B,GATA2,KIAA0319,GRIP1,ADCY6,FIG4,GFI1,SLC45A3,FES,RIMS2,PAK1,VEGFC,DISC1,BDNF,LZTS3,RAPGEF2,VLDLR,EFNA3,SMARCD3,SNAP25,SDK1,BAIAP2,MAP1B,NEGR1,DKK1,ID3,DOCK7,MYADM,ADGRB3,TERT,FBN1,HEYL,CSF1,BMP4,SEMA3A,CDH2,SHOX2,SHTN1,FOXA1 |
| 4.485e-07 | -14.62 | dendrite | cellular component | GO:0030425 | 579 | 92 | 18223 | 1724 |
DNM3,FGF13,GRIK2,PRSS12,C4A,KIF5A,ABHD13,CANX,KIF21B,PRR7,DNER,PPP1R9A,NCS1,KCNAB1,KCNN2,DAB2IP,CTTN,KCNB2,DBN1,GPM6A,KCNIP3,ATF4,FZD4,WLS,SHANK2,LRRK2,PREX1,NLGN4X,FEZ1,PRKAR2B,KCND3,AMIGO1,TTLL7,GABARAPL1,CAMK2N1,HTR7,TRIM9,MAP2,PLK2,WFS1,RGS10,INPP5F,BMPR1A,PPARGC1A,APBA2,MAGI2,CTTNBP2,COBL,LZTS1,CTNND2,PRKAA2,MYO1D,NECAB2,FARP1,BMPR2,APBB1,LRP4,OPHN1,GABRG2,P2RY1,APBA1,EPHB1,KCNC4,ARHGAP44,NEDD4,MAP1A,GRIP1,TRIM3,BNIP3,MPDZ,NPTXR,ZNF385A,ATP2B1,CHRM3,PAK1,DPYSL5,BDNF,HOMER2,ARHGAP32,RACK1,OR11H4,CPEB1,BAIAP2,HOMER3,MAP1B,SH3GL2,RPL28,GNAO1,MPP2,SEMA3A,KIF1B,MME |
| 4.572e-07 | -14.60 | middle_third | COSMIC cancer mutations | middle_third | 3622 | 434 | 17385 | 1698 |
DOC2A,MYCBP2,ADAL,TCP11L2,SIDT1,PRSS12,RECK,LDLR,MCOLN3,GATA3,TUBE1,KIAA1217,CA8,AARS,RAC3,DACH2,EYA4,STK24,HECTD2,TXNDC5,FBXO32,TGFBR3,SLC16A2,PPFIA2,CFHR1,KCNS3,ATRNL1,BEND4,MAGEA6,RCAN3,VWA5A,POU3F3,TBC1D8,SMAD9,KLHL23,WISP3,KLHL4,GJB2,LRRK2,SLC25A28,ABCC2,F12,CA13,GPC6,GPR150,SPATA9,ZNF266,ATP7B,ENTPD7,SEMA3C,ZBTB20,UNC5B,LZTS1,MEF2C,SEMA6B,LRFN5,SCN5A,TMEM63C,LATS2,CELSR1,EHHADH,ZHX3,SCN8A,ITGA6,DHCR24,TJP1,GPSM2,APBA1,DYNC1I1,MECOM,SYCP2,ABLIM1,NAV1,FRY,KIAA1671,C1QL4,VWDE,RUNDC3B,SRGAP1,OPN3,SLC16A9,MPDZ,TOX,CADPS2,DENND1C,FIGN,MOXD1,FAM155A,FMNL2,LRP12,RIMS2,EPB41L5,TBC1D8B,MYO10,PLEKHA8,COL4A4,STAT4,ARID5B,DCHS1,ZNF605,FASN,RYR2,TTC30A,HIP1,DAGLA,BEX4,XKR9,TEX15,VPS37D,SH3GL2,ADAMTS3,LRRIQ3,MATN2,MPP2,SQLE,SLFN5,MTG1,FRMPD3,EPHA3,AMOTL1,ZNF516,TCTN2,RASAL2,CCDC110,MYO1B,PLXNA2,COL14A1,TBC1D30,TIAM2,TXNRD3,NELL2,EPB41L3,ZNF827,ZNF438,KMO,COL25A1,ALDOC,NBEA,DAB2IP,PDE4D,FAM155B,JAKMIP3,DNAH5,MYT1,SCN3A,DOCK8,DZANK1,VNN2,GARS,COL6A2,RNF145,KCNH5,SHANK2,TRAM1L1,ADCY1,NLGN4X,ATF3,DSP,ASPH,MAGI3,IQCH,WFS1,INPP4B,ZNF704,PLD5,NR3C2,HACE1,DENND5B,MYO1D,FARP1,TMEM132C,WDR17,EPS8,CBS,CREB5,PKN1,EPHB1,ZNF219,TSPAN17,NEO1,MGAT1,AFF2,GAS2L3,RALGAPA2,DYNC2H1,SMPDL3A,MED12L,B4GALT6,TRPM4,MN1,VAV3,ARHGEF28,SYNPO2,SH3BP2,ARAP2,CACNA1E,MCF2L2,PTPN13,RASA3,HOXA1,ZIC1,GALNT3,PTPRC,TRIB3,NSD1,PLOD2,PLPPR2,GNAO1,XBP1,SLCO5A1,SVIL,NEK11,DOCK6,ATP2B4,EXPH5,FGF13,KIF5A,LILRB1,FAM13A,HMCN1,FSTL5,CHST10,CEP85L,RTN1,LGI2,FKBP9,RUFY4,RPS6KA2,KCNN2,HPS1,ABI3BP,MARVELD2,TMEM143,TRPC1,JAKMIP2,KIAA1614,SLC2A12,PCOLCE2,TLN2,PTPRE,MYRIP,TLR4,OR2W3,NEB,SLIT2,ZNF391,GPM6A,SLC3A2,SESN2,COL4A3,ANK2,ZNF565,TMEM200C,CR2,TCERG1L,SESN1,NT5DC2,TRIM9,GSN,KLF12,TECPR2,ERN1,TNFRSF1A,MAGI2,TC2N,HS6ST3,CHMP4C,PCSK5,SV2B,MOCOS,FN1,OTOGL,ELOVL7,SETBP1,CHADL,CHSY1,PFN2,MLC1,CD7,FHOD3,KIAA1958,CA2,SLC30A4,ABCA5,FRAS1,SAMD11,GAN,HS3ST5,FAM107B,ADCY6,SLCO4C1,RNF148,NCEH1,LRP3,CHSY3,IL17RD,UNC5C,PCDH10,SLITRK2,SLC27A2,MSTN,HOMER2,MGAT4B,TMTC4,SPATA13,OBSCN,SLITRK5,WWC1,PRDM1,KHDRBS2,GPR19,GRIK4,PLAGL1,FAT1,PTPRN2,FBRSL1,SEMA3A,XKR4,CXCR5,DMXL2,EML5,NEK10,CFH,AKAP5,CELSR3,PSTPIP2,LPCAT2,PLEKHA5,XYLT1,MORC4,COL18A1,COBLL1,NTRK3,FAM198B,SEZ6L2,LPIN3,DENND3,KBTBD11,TNKS1BP1,RADIL,DOCK2,PCLO,SP8,CYP26A1,SCIN,FAM131B,ZNF362,COL22A1,TACC2,PPFIBP1,LHX6,ZNF521,BCL6,MAP7,MYH15,WWC2,MET,SCN2A,ALG10B,GLI1,SUSD3,DPP10,EVL,CSN2,TDRD3,PRDM13,C3orf52,CD40,DOCK5,FRK,JAM3,TPK1,WARS,RANBP2,NRG3,PTPRJ,TMPRSS9,ITGA2,PTPRS,HGF,CYP2U1,ZNF701,C8orf48,CTNND2,PSPH,MAN2B2,TNIK,PCDH18,ARHGEF11,TSPAN15,RUSC2,APBB1,LRP4,CLSTN2,SELL,RASD1,IGF2BP2,SEL1L3,ARHGAP44,FOXP2,FSD1,MAP1A,DSG2,TSC22D1,KIAA0319,MARCH3,SGK1,KIAA0408,DLGAP1,RIN2,CARD6,HNF4G,FOXN3,SYBU,OGDHL,MEI1,PRICKLE1,NPDC1,SMPDL3B,HOMER3,RERE,GPR37,ICA1,DOCK7,MYADM,FBN1,L3MBTL4,THSD7B,SH3BGRL2,DLG2,KIF21A,TBC1D4,FILIP1,SLC16A10 |
| 4.594e-07 | -14.59 | bone | COSMIC cancer mutations | bone | 8380 | 915 | 17385 | 1698 |
ARHGAP26,DOC2A,THOC5,ADAL,FLVCR2,GRIK2,AASS,CNTNAP3,PRSS12,RECK,DNAJC3,LSM11,FAM102B,ALG1L,NPM1,STAT5B,CTBP2,CEBPA,CADM2,CHAC1,BCAN,DOCK3,KIAA1217,CA8,EYA4,NOS1AP,PCDH7,BAG3,TGFBR3,PPFIA2,TMED9,PPP2R2B,COG3,CPE,TSHR,POU3F3,DCC,KLHL23,CAP2,GJB2,LRRK2,ELMOD1,ABCC2,F12,MFSD6,INTS6,PYCR1,SLC7A1,ZNF266,ATP7B,MAP9,ALDOA,ARHGAP28,BBC3,ERCC5,INPP5F,ZBTB20,DNHD1,TMEFF2,CRYL1,MEF2C,CARS,SCN5A,LATS2,TMEM63C,STOX2,CYP2J2,ITGA6,TJP1,FOXG1,BBS9,HPCAL4,SYCP2,RSL24D1,FRY,PAIP2B,FAM189A1,CACNB2,TOX,ALPK1,DENND1C,FIGN,NCAM1,MOXD1,FMNL2,GFRA1,LRP12,HMGCR,BDNF,SLC37A1,PNP,KCNQ3,MYO10,SPATA6,ARID5B,ZNF605,FASN,FHL2,RYR2,HIP1,AIG1,ST6GALNAC3,ZBBX,TAF4B,DHX32,BEX4,CACHD1,TEX15,TMCO3,SH3GL2,ADAMTS3,EMILIN2,CDH17,CLMN,LAPTM4B,CDH2,TRPC3,DOCK9,TFCP2L1,DNM3,ZNF516,GALNT12,MYO1B,LRRCC1,ABHD13,PKP2,ADD2,IL13RA1,GRK6,LCP2,NRXN1,SLC19A2,GPR15,EPB41L3,RNF150,TLR3,GPRIN1,COL25A1,CNKSR3,DACT1,MAGEA3,ALDH1L1,RTKN2,DNAH5,MYT1,SNX10,KCNB2,SCN3A,DOCK8,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,FZD4,KCNH5,TRAM1L1,ADCY1,RAB38,DSP,ASPH,ZNF618,METAP1D,FGFR1,MAGI3,GJC1,SLC39A14,ENTPD1,ARHGAP21,IQCH,GYPC,WFS1,GPR160,WWTR1,LAMB1,INPP4B,PAM,PLEKHG1,ALG11,TNFSF15,PLD5,DBP,C2orf88,CCDC148,FARP1,WDR17,CKAP2,ESRP1,BACE1,IPO5,UBAC2,NKAIN2,PSD3,P2RY1,CREB5,PKN1,EPHB1,KCNC4,BEX2,COL27A1,NEO1,PCBP4,GAS2L3,MYO6,ZFP36L2,MED12L,FES,PARP9,ULBP1,TRPM4,PDLIM7,MN1,RAPGEF2,ELOVL3,RASA3,ATP11A,SNTB1,HEG1,GALNT3,PTPRC,TRIB3,NSD1,PCDHB7,PLOD2,OSBPL5,NEK11,BMP4,HK1,DOCK6,DCBLD1,FOXA1,PHC1,TLL2,PHACTR3,NMNAT3,CACNG3,TRIM2,FGF13,SYT12,FHDC1,ASS1,NDRG2,LILRB1,MGAT5B,ITPR2,SYT14,FSTL5,CCNJ,ANKRD42,RUFY4,CPNE2,FKBP9,EOMES,KCNAB1,SEC16B,KCNN2,TMEM86A,ITGB3,TMEM143,COL19A1,JAKMIP2,KIAA1614,TLN2,ETV1,ENO1,TLR4,NEB,PGBD5,DBN1,SLC3A2,GCNT2,MARK1,KCNIP3,ATF4,ABCC4,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,PLEKHA1,TCERG1L,SESN1,CRYBG3,TSKU,SPNS1,TCF7L1,KCNMB4,INSIG1,KLF12,MAP2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,HS6ST3,LONRF1,PRKAA2,KCNV1,RUNX2,STXBP5L,ITPRIP,CHCHD7,SETBP1,ZNF215,IL18R1,PGAP1,DOK5,FHOD3,HSPA12B,RNF180,KIAA1958,KIAA0895,ZBTB38,SEMA4F,IGF1R,ABCA5,BCHE,ZNF440,FRAS1,HS3ST5,SMTN,LRP6,ADCY6,SLCO4C1,FAR2,NIPAL2,CKAP4,FGFR4,CHSY3,UNC5C,BTNL9,RNF170,MGAT4B,GPSM1,TMTC4,WDR25,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,TEX9,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,ATPAF2,CSF1,PLD1,SEMA3A,MME,SIX2,SFN,CFH,AKAP5,DOCK1,RHPN2,RNF24,ZNF83,NTRK3,SLC7A2,FAM198B,KIF21B,LPIN3,SEZ6L2,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,CYP26A1,TBC1D19,FAM131B,SLC22A17,TACC2,MYO3B,BCL6,ZDHHC23,MYH15,CLVS2,SCN2A,INTU,TMEM67,EVL,THSD4,PRDM13,ACO1,FGF12,CHRNA6,FRK,C4BPB,IFT81,RANBP2,NRG3,PTPRJ,ITGA2,PTPRS,SUSD4,CTNND2,CNTN1,HEY1,MAN2B2,TENM1,PCDH18,DYRK3,SLC6A9,KLHL13,RUSC2,APBB1,MCTP2,GABRG2,RASD1,PPP2R3A,SLC35F1,FOXP2,TTC1,TECPR1,MAP1A,RASD2,KCNMB3,TSC22D1,PRICKLE2,KIAA0408,SH3PXD2B,KLF9,PCK2,KIAA1211,ATP2B1,CES3,DLGAP1,PPP1R3D,MICAL2,LRRIQ1,NUAK2,FERMT2,PALLD,MGMT,SMPDL3B,HOMER3,DKK1,DDAH1,DOCK7,FAT4,FBN1,L3MBTL4,ZNF214,DLG2,SLC22A15,SLC1A5,TBC1D4,PTGES,KIF1B,FILIP1,CACNA2D1,ZNF235,FAM171B,MYCBP2,PLBD2,PPP4R4,LGR4,SIDT1,TTC39B,TCP11L2,ATP8A1,LDLR,PPFIBP2,GATA3,ENAH,AARS,TRPS1,ZFYVE28,CFHR1,SLC22A18,SLC16A2,SERINC2,NDUFB8,KCNS3,ATRNL1,BEND4,MAGEA6,VWA5A,PLTP,GLDC,TBC1D8,DCDC1,ACVR1C,NR6A1,WISP3,FAM84A,LRMP,TNS1,ACVR2B,SAV1,ZDHHC14,GPC6,SFXN1,SH3RF1,ENPP6,NCKAP1L,PLK2,RASGRF2,CCBE1,BMP1,MAPK13,DSEL,NRP1,TANC2,UNC5B,SEMA6B,LRFN5,MRC2,INPPL1,FAM124A,CELSR1,PTPRD,ZHX3,TBC1D1,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,MRPL22,SLC1A3,WDFY4,APBA1,TNFRSF19,ADSSL1,DYNC1I1,MECOM,MTUS1,ABLIM1,RALGPS2,SLC7A11,CNTN4,KIAA1257,PIK3AP1,MYC,RUNDC3B,PRELID1,PRKG1,CPXM2,GRIP1,SLC16A9,MPDZ,GPR161,IGSF3,EPB41L5,PTCH2,TBC1D8B,SLC36A1,PLEKHA8,COL4A4,VLDLR,RAPGEF4,DCHS1,PACSIN3,KIAA1324L,TTC30A,TTYH2,CDC42BPA,PLCB1,FAM162A,DAGLA,VPS37D,PLEKHH2,PMEPA1,PKN3,PELI2,CECR2,THBS4,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,SLFN5,AMPD1,ACSM3,EPHA3,PLA2G4A,TCTN2,ELOVL4,RASAL2,RHOD,CCDC110,GPR65,PLXNA2,CHUK,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,TMEM53,ZNF827,SPEG,ALDOC,SHF,SCRN1,PDE4D,SERPINH1,TRDMT1,VNN2,TMEM43,SHANK2,PANK1,PREX1,SATB2,CBY1,PRKCQ,PYGO1,ATP1B1,ATP10D,DCBLD2,IKZF3,PRKCB,TDO2,BMPR1A,CTTNBP2,COBL,STON2,MID1,HACE1,DENND5B,ANO10,MYO1D,ANKRD13D,MXI1,PLSCR4,CCNJL,HERC5,GABRR2,RGS7,GDPD5,TPD52L1,NEDD4,RASSF8,RGS17,LRRC55,SOAT2,MGAT1,GPR155,SGK3,RALGAPA2,SLC6A15,DYNC2H1,ERRFI1,TBC1D9,SMPDL3A,B4GALT6,TMC7,VAV3,ARHGEF28,ALDH2,ARAP2,PXN,SH3BP2,SYNPO2,CACNA1E,MPP1,PTPN13,ZDHHC15,GUCY1A2,ZIC1,FGR,OR2T33,TERT,MCC,SVIL,GRIN2D,MYOM2,TNFRSF17,SLC43A1,ATP1A3,NUDT17,EXPH5,ACSL1,KIF5A,UGDH,PTPN21,ACTL8,IKZF2,DNER,KREMEN1,SLCO3A1,HMCN1,RTN1,ARHGEF10L,ADPRHL1,LGI2,PPM1E,SIPA1L2,AKAP7,ABI3BP,SLC10A7,ANKFN1,TRPC1,SLC2A12,PCOLCE2,PTPRE,OR2W3,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,TNK2,ATL1,GPM6A,SESN2,SKAP2,JPH1,ROR1,SGK2,RNF44,SERGEF,TMEM132B,GSN,AK1,GPRC5B,HPSE,ITGBL1,NCOA7,TNFSF4,APBA2,PCSK5,GPT2,UST,BCL11B,SV2B,ZNF395,FN1,RHOBTB1,BVES,LAMC3,ATP6V1E2,GALNT13,FAM81A,PHGDH,SATB1,PCDHB14,RNF141,CA2,EEF2,LIMCH1,RNF148,NCEH1,CAND2,NOS3,CDH26,GPR176,PCDH10,PODXL2,SLITRK2,MSTN,PARD3B,EDEM3,SDC3,WWC1,PRDM1,B4GALNT3,AMDHD1,STEAP1,GLCE,TMEM154,KIAA0355,FAT1,HK2,RAI14,SH3BP4,TMEM117,PTPRN2,EGFL7,FNBP1L,OSBPL6,XKR4,DMXL2,EML5,NEK10,ZSWIM5,SORBS1,CELSR3,PLEKHA5,PSTPIP2,HECW2,MORC4,COL18A1,COBLL1,TDRKH,DOCK2,ZSCAN5A,SCIN,COL22A1,PDZD8,SETDB2,UNC13B,CDC14B,RPS6KL1,PPFIBP1,REEP1,ZNF521,MAP7,ACVR2A,STEAP3,FHIT,PROS1,MDH1B,MET,POU2F2,ZNF460,NTNG1,SEMA6C,PHLDB2,PTPRU,PTPN6,TES,MVD,TCEAL3,SYNJ2BP,CD40,TTLL7,DOCK5,TPK1,BCL11A,ARMC4,ZNF93,LMLN,BACH2,TRIM34,KPNA3,TMPRSS9,CYP2U1,LIFR,PSPH,MAST1,TNIK,PRSS16,ENO2,ARHGEF11,CLGN,TSPAN15,REL,LRP4,SSX1,NSUN6,CLSTN2,COL4A5,OVOL2,FAM174B,SEL1L3,BMP6,SYDE2,FSD1,CHN2,PRKCD,EHD3,DSG2,KIAA0319,TRIM3,AFAP1L2,IPCEF1,IQGAP3,FKBP14,TNFRSF11A,RBMS2,RIN2,CARD6,RAB3B,MSX1,HNF4G,CRIM1,NR4A1,ESRRG,CYTH3,SYBU,OGDHL,GRID1,MEI1,MARS,CCNG1,ARHGAP32,ZFPM2,GALNT14,NAALADL2,LRAT,MAP1B,RERE,CTIF,ADAMTS17,GPR37,DPY19L2,MFSD9,MYADM,NACC2,RND3,PRCP,MAP2K6,THSD7B,UACA,KIF21A,RNF157,IL9R,NPHP1,ABCG1,SNPH |
| 4.641e-07 | -14.58 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 295 | 57 | 17377 | 1707 |
LATS2,GNG12,RNF144A,PLXNA2,GTF2IRD1,SELL,KCTD12,CTBP2,TDRKH,PHGDH,SATB1,NUDT12,DOCK2,UBTD2,DACH2,PPP1R9A,FKBP11,SYDE2,TGFBR3,KIAA0895,RALGPS2,ITGB3,CCDC122,WWC2,PTPRCAP,ZNF518B,SYK,PAK1,GCNT2,EIF4E3,GJB2,SLC39A8,HOMER2,VIM,MFSD6,ARRDC4,MAGI3,TPK1,RERE,PTPRC,IFT81,HLF,TMEM237,NCKAP1L,ZNF704,HK2,SVIL,PTPRS,MAOA,TUFT1,EGFL7,GRB10,SMYD3,KCTD1,CRYL1,MEF2C,DOCK9 |
| 4.787e-07 | -14.55 | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | 9495 | 1023 | 17385 | 1698 |
ARHGAP26,THOC5,PDE1B,AASS,CNTNAP3,RECK,DNAJC3,FAM102B,NPM1,STAT5B,CTBP2,CEBPA,CADM2,DOCK3,SNX9,NOS1AP,SKI,PCDH7,EPDR1,BAG3,FBXO32,DNAH6,PMAIP1,PPFIA2,FAAH2,RAP2A,RAB26,PPP2R2B,TMEM37,COG3,TSHR,KLHL29,NKX2-1,SMAD9,DCC,TGFA,CAP2,LRRK2,NFIA,FEZ1,PRKAR2B,KCND3,FGF17,F12,INTS6,CA13,PYCR1,WIPF3,ATP7B,MAP9,ALDOA,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,DNHD1,VASH2,C12orf77,LPP,CRYL1,MEF2C,CARS,SCN5A,GNG12,LATS2,TMEM63C,ITGA6,BTBD9,GPSM2,FOXG1,BBS9,GRPEL2,CHN1,SYCP2,BNIP1,KIAA1671,APLF,FAM189A1,SRGAP1,TOX,CADPS2,ALPK1,FAM84B,ST8SIA1,LOXL4,DENND1C,FIGN,AGL,GLIS1,TSPAN9,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,PNP,KCNQ3,MYO10,STAT4,ARID5B,EFHC2,FASN,FHL2,RYR2,HIP1,SMARCD3,C1R,ST6GALNAC3,ZBBX,MBNL2,SPATA7,DHX32,BEX4,CACHD1,TEX15,TMCO3,RIMKLB,ADAMTS3,EMILIN2,CLMN,LAPTM4B,HOXD13,SPRED3,FBXO27,CDH2,TRPC3,DOCK9,TFCP2L1,NUDT10,DNM3,ZNF516,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,ABHD13,RGS20,BEGAIN,PKP2,IL13RA1,GRK6,COLEC10,LCP2,CDS1,RNF150,EPB41L3,CHRNA5,GPRIN1,DACT1,ALDH1L1,FAM133A,PJA1,FAM155B,ARL4D,RAB27B,JAKMIP3,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,SCN3A,DOCK8,FZD1,DZANK1,SSH3,MYLK3,COL6A2,GAPDH,RNF145,NECAB1,FZD4,KCNH5,TRAM1L1,ADCY1,WNT11,RAB38,TTC28,DSP,ZNF618,FGFR1,MAGI3,GJC1,IRS2,CXCL10,ARHGAP21,IQCH,WFS1,WWTR1,LAMB1,INPP4B,PAM,PLEKHG1,P4HA1,TNFSF15,FAM149A,PLD5,KLHL31,LRRC27,RAB30,CGB2,FARP1,WDR17,ROBO2,EDA2R,CKAP2,GCAT,FZD8,PLAG1,BIK,IPO5,PSD3,GAS6,PKN1,EPHB1,ZNF219,TSPAN17,BEX2,COL27A1,NEO1,PCBP4,MCF2L,GAS2L3,GHR,ZFP36L2,MED12L,FES,PDLIM7,TRPM4,B9D1,MN1,BCL7A,RAB6B,MCF2L2,RAPGEF2,AK4,RASA3,ATP11A,SNTB1,HEG1,PTPRC,TRIB3,ID3,NSD1,PCDHB7,PLOD2,PLPPR2,AKT3,GNAO1,SRD5A3,OSBPL5,XBP1,SLCO5A1,NEK11,PIP5KL1,BMP4,HK1,SHOX2,DOCK6,FOXA1,BTRC,PHC1,PHACTR3,NBPF4,TRIM2,FGF13,TRIM16,SYT12,FHDC1,LILRB1,MGAT5B,ITPR2,NUP62CL,NOVA1,FSTL5,PLS3,RND2,FKBP9,RPS6KA2,KCNN2,SEC16B,ITGB3,LIN7A,TLN2,TMEM132E,ETV1,TLR4,ENO1,RAPGEF5,NEB,DBN1,ITGB7,GCNT2,MARK1,CD55,PNRC1,COL4A3,SPOCD1,ANK2,FAM201A,CR2,TTC22,PLEKHA1,BATF,SESN1,NT5DC2,PLEKHB1,TSKU,DYRK1B,TRIM9,KCNMB4,MAP2,GNB4,ERN1,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,MLLT3,TC2N,RRAGD,CHMP4C,PRKAA2,KCNV1,RGS16,RUNX2,LGALS3,STXBP5L,SETBP1,RASL11B,ZNF215,ZIC2,MLC1,IL18R1,DOK5,FHOD3,HSPA12B,EFEMP1,NUMBL,KIAA1958,IGF1R,ZNF440,GATA2,FRAS1,PDE10A,SAMD11,SMTN,LRP6,ADCY6,BNIP3,SLCO4C1,FBXL2,PTPRCAP,VGLL4,CKAP4,PAK1,FGFR4,MID2,UNC5C,BTNL9,HOMER2,MGAT4B,GPSM1,TCEA3,SPATA13,PPFIA4,WDR25,STRADB,MAFB,OBSCN,SLITRK5,SDK1,KHDRBS2,TEX9,TBC1D2,MAPKAPK2,KCNK15,MFSD2A,SLC2A6,FBRSL1,PLD1,RNF122,PANK3,MME,SFN,ID1,CFH,AKAP5,DOCK1,RHPN2,RNF24,ZNF83,NTRK3,OR51B4,SLC7A2,KIF21B,SEZ6L2,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,CYP26A1,FAM131B,ZNF362,IDI1,SLC22A17,TACC2,ZDHHC6,MYO3B,BCL6,EEPD1,MYH15,SCN2A,RPS13,GLI1,INTU,TMEM67,EVL,TDRD3,THSD4,PRDM13,ACO1,RNF125,VIM,FBXO36,FRK,PAGE5,SMAD3,RANBP2,PTPRJ,ANKRD31,PTK7,ITGA2,ABI3,PTPRS,MAOA,HGF,SEPT5,TTC39A,MBOAT2,ZNF701,CTNND2,CNTN1,HEY1,MAN2B2,TENM1,PCDH18,DYRK3,LPAR2,NECAB2,IL32,BMPR2,KLHL13,GRB14,RUSC2,APBB1,MCTP2,NLRP14,GABRG2,RASD1,USP30,PPP2R3A,FOXP2,TECPR1,MAP1A,RASD2,KCNMB3,TFAP2A,TSC22D1,SGK1,PRICKLE2,TSPAN13,SH3PXD2B,PCK2,SYK,SLC45A3,KIAA1211,CES3,DUSP1,DLGAP1,PPP1R3D,MICAL2,FOXN3,CRIP2,LITAF,NUAK2,PRICKLE1,TGDS,PALLD,ILDR2,MGMT,HOMER3,DKK1,EBF1,FAT4,FBN1,L3MBTL4,FMO4,ZNF214,SH3BGRL2,DLG2,ZNF474,RPL4,PAX9,SLC1A5,TBC1D4,PTGES,KIF1B,FILIP1,CACNA2D1,C2orf27A,FAM171B,MYCBP2,CGN,PLBD2,PPP4R4,ACVR1,PAGE1,LANCL3,DUSP8,LGR4,SIDT1,LDLR,PPFIBP2,GATA3,ENAH,ADAMTS6,PRKCA,AARS,DACH2,RAC3,SLC9A7,STK24,HECTD2,TRPS1,ZFYVE28,FAM168A,CFHR1,SLC16A2,SERINC2,CHRDL1,ATRNL1,VWA5A,GLDC,GDAP1,ERGIC1,EML6,ACVR1C,WISP3,KLHL3,FAM84A,KLHL4,ALDH1L2,DNAJC6,LRMP,BNIP3L,DEPTOR,MEF2B,SLC25A28,EFHC1,TNS1,ACVR2B,SAV1,ZDHHC14,GPC6,GNAI1,AHRR,SFXN1,HLF,ENPP6,PLK2,ENTPD7,RASGRF2,SEMA3C,MAPK13,SERPINI1,DSEL,SPRY4,NRP1,TANC2,UNC5B,LZTS1,SEMA6B,LRFN5,KLF8,MRC2,INPPL1,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,ST6GAL1,MLF1,GABRB2,OPHN1,TNFRSF10C,WDFY4,TNFRSF19,CHD5,GAS1,MECOM,MTUS1,MCOLN2,IL17D,NAV1,SLC7A11,RALGPS2,CNTN4,ADCK1,NOVA2,PIK3AP1,MYC,VWDE,PRKG1,OPN3,CPXM2,SLC16A9,MPDZ,TSPAN12,SAMD13,FAM155A,RIMS2,GPR161,BOD1,IGSF3,RNF152,PTCH2,RPL26,TBC1D8B,SLC36A1,PLEKHA8,COL4A4,RAPGEF4,DCHS1,KIAA1324L,TTC30A,TTYH2,PEX5L,CCDC85A,CDC42BPA,PLCB1,FAM162A,TMEM74,MMP15,XKR9,PLEKHH2,PMEPA1,PKN3,ISM1,CECR2,THBS4,LRRIQ3,MATN2,MPP2,SQLE,IQSEC2,DHCR7,SMYD3,AMPD1,ANKRD20A5P,ACSM3,FRMPD3,EPHA3,PLA2G4A,AMOTL1,PCSK1N,RASAL2,RNF144A,RHOD,ST14,PLXNA2,OTX1,CHUK,SPATS2L,DDR1,NUDT12,COL14A1,ZFYVE9,TIAM2,CCDC120,NELL2,SPEG,ZNF438,POU5F1B,ALDOC,STARD4,SHF,NBEA,NAP1L3,MARCKS,PDE4D,SERPINH1,GAB2,TRDMT1,PDK1,CYB5R2,SHANK2,PREX1,NLGN4X,PNMA6A,PRKCQ,ATF3,PYGO1,ATP1B1,LINC00896,ZNF711,IKZF3,PRKCB,CCNA1,MAP3K21,GRB10,KLF5,BMPR1A,HS3ST3B1,NR3C2,COBL,STON2,MID1,THOC3,HACE1,DENND5B,ANO10,ANKRD13D,MXI1,EPS8,PRSS35,HERC5,ARL2,GPR180,RGS7,NDFIP2,INPP1,NEDD4,RGS17,IRX5,AFF2,SGK3,ERRFI1,TBC1D9,SMAD6,GFI1,SPRY2,TMC7,VAV3,ALDH2,ARHGEF28,GSTM2,PXN,AGPAT4,MPP1,PTPN13,ZDHHC15,SKAP1,HOXA1,ZIC1,GPLD1,CEBPB,ZFP62,FGR,OR2T33,TERT,NUTM2A,SVIL,MYOM2,TNFRSF17,OCLN,DDIT3,B4GALT7,MPZL3,KIF5A,PTPN21,C20orf194,ANKRD18A,SLC2A13,ABAT,ABHD4,IKZF2,DNER,RBM11,KREMEN1,SLCO3A1,HMCN1,CEP85L,FKBP11,RTN1,ARHGEF10L,PPM1E,SIPA1L2,AKAP7,DLX6,SLC10A7,ANKFN1,POF1B,CNNM2,HRK,PCOLCE2,CTTN,PTPRE,OR2W3,SLIT2,RASGRP1,PDGFRB,PRKACB,ATL1,TNK2,SESN2,SKAP2,CAPN5,ZNF565,YAP1,ROR1,TMEM47,COTL1,SGK2,RNF44,SERGEF,EML1,TMEM132B,AK1,GPRC5B,HPSE,NCAM2,CCDC169,NCOA7,TNFSF4,PPARGC1A,APBA2,MAGI2,FRMD5,PCSK5,GPT2,BCL11B,SV2B,FN1,RHOBTB1,SCART1,JDP2,FBXO4,RIMKLA,CYP4V2,LAMC3,PHGDH,SATB1,DDIT4,PCDHB14,RNF141,OTUD1,CA2,EEF2,EBF4,FAM107B,RNF148,LRP3,SNX7,NOS3,CDH26,ANKRD20A2,PCDH10,RHOQ,SLITRK2,MSTN,SH2D2A,PARD3B,SDC3,WWC1,DUSP9,PRDM1,LHPP,B4GALNT3,STEAP1,AMDHD1,HERPUD1,TMEM154,CSAG1,NCR3LG1,FAT1,HK2,RAB31,SH3BP4,PTPRN2,EGFL7,NKX2-8,FNBP1L,OSBPL6,CREB3L2,CXCR5,DMXL2,EML5,NEK10,ZSWIM5,SORBS1,CELSR3,PLEKHA5,PSTPIP2,ARHGAP22,HECW2,MORC4,COL18A1,BCL6B,DOCK2,ZSCAN5A,COL22A1,PDZD8,UNC13B,CDC14B,PPFIBP1,KAZN,RPS6KL1,C12orf60,ZNF521,MAP7,ACVR2A,MET,POU2F2,HSPA2,SEMA6C,SP140L,ALG10B,SUSD3,PHLDB2,FER,PTPRU,PTPN6,CD40,TTLL7,DOCK5,BCL11A,ZNF569,ARMC4,MAGEA12,ZNF93,LMLN,KPNA3,BACH2,TRIM34,EIF4EBP1,RGS10,DUSP19,SOHLH2,DISP1,CYP2U1,RNF130,LIFR,PSPH,MAST1,OR51B5,TNIK,PRSS16,ENO2,ARHGEF11,CLGN,TSPAN15,REL,LRP4,TNFSF13B,CLSTN2,COL4A5,IGF2BP2,FAM174B,RAB11FIP5,FSD1,KCNJ4,CHN2,PRKCD,EHD3,TRIM3,AFAP1L2,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,CARD6,RAB3B,USP2,NR4A1,SYBU,CYTH3,OGDHL,GRID1,ASAP3,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,GALNT14,TLR6,NAALADL2,LRAT,MAP1B,CTIF,ADAMTS17,SUGT1,ICA1,EDA,MFSD9,NACC2,RND3,ACER2,MAP2K6,THSD7B,KIAA0513,KIF21A,RPS12,GEM,RNF157,IL9R,MMP16,NPHP1,ABCG1 |
| 4.834e-07 | -14.54 | bile_duct | COSMIC cancer mutations | bile_duct | 15555 | 1576 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,COL6A2,GAPDH,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZNF440,SMTN,HS3ST5,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,OR11H4,TAF4B,MBNL2,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH,STOM |
| 4.834e-07 | -14.54 | biliary_tract-bile_duct-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-adenocarcinoma | 15555 | 1576 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,C3orf67,COL6A2,GAPDH,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZNF440,SMTN,HS3ST5,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,PODXL2,RHOQ,SLITRK2,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,OR11H4,TAF4B,MBNL2,DHX32,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,MID2,UNC5C,RNF170,SLC27A2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,DAGLA,XKR9,VPS37D,PKN3,PMEPA1,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,GPR180,GABRR2,RGS7,GDPD5,NEDD4,RGS17,SOAT2,MGAT1,SGK3,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,SNPH,STOM |
| 4.848e-07 | -14.54 | dendritic tree | cellular component | GO:0097447 | 580 | 92 | 18223 | 1724 |
DNM3,FGF13,GRIK2,PRSS12,C4A,KIF5A,ABHD13,CANX,KIF21B,PRR7,DNER,PPP1R9A,NCS1,KCNAB1,KCNN2,DAB2IP,CTTN,KCNB2,DBN1,GPM6A,KCNIP3,ATF4,FZD4,WLS,SHANK2,LRRK2,PREX1,NLGN4X,FEZ1,PRKAR2B,KCND3,AMIGO1,TTLL7,GABARAPL1,CAMK2N1,HTR7,TRIM9,MAP2,PLK2,WFS1,RGS10,INPP5F,BMPR1A,PPARGC1A,APBA2,MAGI2,CTTNBP2,COBL,LZTS1,CTNND2,PRKAA2,MYO1D,NECAB2,FARP1,BMPR2,APBB1,LRP4,OPHN1,GABRG2,P2RY1,APBA1,EPHB1,KCNC4,ARHGAP44,NEDD4,MAP1A,GRIP1,TRIM3,BNIP3,MPDZ,NPTXR,ZNF385A,ATP2B1,CHRM3,PAK1,DPYSL5,BDNF,HOMER2,ARHGAP32,RACK1,OR11H4,CPEB1,BAIAP2,HOMER3,MAP1B,SH3GL2,RPL28,GNAO1,MPP2,SEMA3A,KIF1B,MME |
| 4.875e-07 | -14.53 | GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_UP | MSigDB lists | GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_UP | 185 | 41 | 17377 | 1707 |
FN1,RASAL2,BMPR2,GCAT,ST6GAL1,ARHGAP22,PKP2,FKBP11,CD53,TXNDC5,CYP51A1,RNF180,FBXO32,ASNS,NAV1,GTSF1,MYC,SAMD11,GAS2L3,BCL6,MPDZ,NCAM1,CKAP4,B4GALT6,ZNF629,PFKFB4,ATL1,SLC40A1,CAP2,HOMER2,BNIP3L,PRRG1,RASA3,C3orf70,C4orf19,FGFR1,MATN2,PTPRS,SQLE,TNFRSF17,MEF2C |
| 4.899e-07 | -14.53 | GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 159 | 37 | 17377 | 1707 |
EFNB2,MOCOS,TNIK,LPAR2,MVK,ZIC2,SFXN3,FAM174B,TNFRSF19,CACNB4,TBC1D30,F3,QPRT,EOMES,PPFIBP1,TOX,ARL4D,JAM2,CEBPD,GPR176,GDAP1,TUBA1A,CRIM1,KLHL3,TTYH2,PRKCQ,CD40,SKAP1,PMEPA1,HEYL,MFSD2A,SLC2A6,HK2,HGF,HS3ST3B1,TNFRSF17,B4GALT7 |
| 4.960e-07 | -14.52 | ATACCTC,MIR-202 | MSigDB lists | ATACCTC,MIR-202 | 172 | 39 | 17377 | 1707 |
EPHA3,CGN,TBKBP1,RGS16,FARP1,RBFOX2,YPEL2,ABHD13,PGAP1,HECTD2,GALNT1,CHN2,HMGCS1,SLC30A4,GHR,ACVR2A,COL19A1,LOXL4,FAR2,MYRIP,DUSP1,TMC7,BCL7A,PNP,FOXN3,CACNA1E,CYTH3,HOMER2,SHANK2,DUSP9,ADAMTS3,EIF4EBP1,TECPR2,HK2,PPARGC1A,XKR4,KIF1B,PURG,SLC16A10 |
| 4.960e-07 | -14.52 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_UP | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_UP | 172 | 39 | 17377 | 1707 |
EFNB2,PLSCR4,RBFOX2,GALNT6,ELOVL7,BLVRB,ARHGAP22,CANX,SPIRE1,FKBP11,FKBP9,RNF150,PRTFDC1,FRY,EEF2,BACE2,ZNF521,MAP7,BEND4,BNIP3,SERPINH1,RAB27B,MAST4,JAM2,PNP,SPATA6,DEPTOR,CALCRL,SNTB1,SKAP1,PTPRC,GSTO2,PLOD2,PLXDC2,LAPTM4B,SLC22A15,STON2,MLLT3,STOM |
| 5.081e-07 | -14.49 | GO_EPITHELIUM_DEVELOPMENT | MSigDB lists | GO_EPITHELIUM_DEVELOPMENT | 892 | 133 | 17377 | 1707 |
EXPH5,ACVR1,LGR4,ACTL8,MCOLN3,GATA3,AARS,PLS3,SKI,EPCAM,GRHL1,DLX6,MARVELD2,RAP2A,GSTM3,SLIT2,POU3F3,PRKACB,NKX2-1,SMAD9,KLHL3,CAPN5,YAP1,ACVR2B,SAV1,ARHGEF26,BDH2,SEMA3C,TMEFF2,NRP1,MAGI2,MEF2C,EFNB2,BCL11B,LATS2,CELSR1,LGALS3,TJP1,GPSM2,PHGDH,TNFRSF19,SPINK5,SATB1,CA2,SLC7A11,PDZD7,FLRT3,FRAS1,MYC,LRP6,BARX1,PTCH2,PAK1,EPB41L5,DCHS1,RYR2,PRDM1,CECR2,CSF1,HEYL,WDR19,HOXD13,CDH2,SEMA3A,SFN,SIX2,TFCP2L1,ID1,ST14,PLXNA2,RGS20,COL18A1,NTRK3,DDR1,SETDB2,ALDOC,KAZN,DACT1,PDE4D,MET,SNAI2,FZD1,GLI1,INTU,SOX21,NKX3-2,WNT11,VIM,ATOH1,DSP,FGFR1,SMAD3,PTK7,ITGA2,PTPRS,KLF5,BMPR1A,COBL,HEY1,ROBO2,EDA2R,BMPR2,LRP4,OVOL2,BMP6,PPP2R3A,NKX6-1,TFAP2A,ACTA2,ERRFI1,SMAD6,SPRY2,B9D1,VEGFC,SLC40A1,MICAL2,MSX1,KDM5B,RAPGEF2,PRICKLE1,FNDC3A,PALLD,MGMT,HEG1,DKK1,CEBPB,ID3,FAT4,MYADM,XBP1,BMP4,BTRC,FOXA1 |
| 5.131e-07 | -14.48 | GO_ORGAN_MORPHOGENESIS | MSigDB lists | GO_ORGAN_MORPHOGENESIS | 826 | 125 | 17377 | 1707 |
ACVR1,ID1,LGR4,OTX1,GATA3,PKP2,COL18A1,DDR1,SEMA6A,CTNNA2,TRPS1,SKI,TGFBR3,SETDB2,DLX6,SERPINH1,CPE,PERP,PDGFRB,SNAI2,GLI1,NKX2-1,FZD1,EVL,KLHL3,NKX3-2,LRRK2,YAP1,SATB2,WNT11,ACVR2B,PLEKHA1,ATOH1,SAV1,DSP,FGFR1,TSKU,SMAD3,NRG3,INSIG1,PTK7,LAMB1,ITGA2,WWTR1,PAM,BMP1,SEMA3C,DLX2,BMPR1A,NRP1,TPM1,MEF2C,HEY1,EFNB2,BCL11B,SCN5A,INPPL1,RUNX2,CELSR1,BMPR2,ITGA6,PLAG1,LRP4,OVOL2,CHSY1,EPHB1,BMP6,PHLDA2,COL27A1,PPP2R3A,NEDD4,NKX6-1,EFEMP1,SYCP2,ABLIM1,CA2,PDZD7,GATA2,FRAS1,MYC,TFAP2A,ACTA2,LRP6,TSPAN12,ERRFI1,SPRY2,SYK,VEGFC,MICAL2,ENAM,SLC40A1,MSX1,KDM5B,DCHS1,ARID5B,FHL2,RYR2,SMARCD3,MAFB,PRDM1,SDK1,ZFPM2,HOXA1,ZIC1,DKK1,HEG1,CEBPB,ID3,FAT4,FBN1,HEYL,CSF1,WDR19,PCGF2,TUFT1,HOXD13,PAX9,BMP4,SEMA3A,SHOX2,CDH2,MMP16,FOXA1,BTRC,SIX2 |
| 5.156e-07 | -14.48 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP | 192 | 42 | 17377 | 1707 |
PLA2G4A,HEBP1,KCTD12,TJP1,CD7,IL18R1,FHOD3,CA2,GATA2,RAP2A,ZNF521,TSC22D1,GSTM3,DAB2IP,PTPRE,SMAD6,FES,PAK1,VAV3,ANTXR2,RHOQ,GCNT2,SKAP2,LITAF,SHISA2,ARRDC4,MFSD6,DOCK5,BCL11A,ENTPD1,DOCK7,ICA1,HLF,MYADM,PRCP,RAI14,RGS10,RAB31,CDH17,LRRK1,GEM,MEF2C |
| 5.330e-07 | -14.44 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN | 179 | 40 | 17377 | 1707 |
ALOX5AP,ZHX3,TBC1D1,MYO1B,ENAH,IKZF2,TRPS1,PAIP2B,PPFIBP1,BCL6,TSPAN13,BOD1,PHLDB2,VAV3,SH3BP2,SLC39A8,STRADB,CR2,PRICKLE1,CALCRL,ARHGAP32,PLEKHA1,CD40,SAV1,SKAP1,SESN1,ATP10D,BCL11A,ENPP1,BACH2,HPSE,KIAA0355,PRCP,GPR160,KCNG1,SERPINI1,PIK3C2B,HS3ST3B1,RAB30,MEF2C |
| 5.415e-07 | -14.43 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | 233 | 48 | 17377 | 1707 |
IL15,PRSS12,BLVRB,SSX1,CREB5,DYNC1I1,SEL1L3,SLCO3A1,PHLDA2,TTC1,EPCAM,SYCP2,MAP1A,SLC7A11,KIAA0319,ACTA2,SERPINH1,TSPAN9,CTH,DUSP1,LAMP3,SLC3A2,CAP2,ATF3,PALLD,MAP1B,WARS,GABARAPL1,HEG1,CEBPB,SLC7A1,PDLIM3,NACC2,MAP2,PLK2,THBS4,FAT1,P4HA2,WWTR1,SLC7A5,BBC3,GEM,MAPK10,TTC39A,KIF1B,DDIT3,ATP2B4,ABCG1 |
| 5.418e-07 | -14.43 | face | COSMIC cancer mutations | face | 2182 | 279 | 17385 | 1698 |
MYCBP2,CTBP2,BCAN,DACH2,NOS1AP,TRPS1,TGFBR3,CHRDL1,ATRNL1,PPP2R2B,DCC,ALDH1L2,LRRK2,LRMP,DEPTOR,ABCC2,TNS1,FGF17,GPC6,SFXN1,ATP7B,RASGRF2,MAP9,INPP5F,DSEL,NRP1,LRFN5,INPPL1,FAM124A,CELSR1,EHHADH,PTPRD,ZHX3,CYP2J2,APBA1,DYNC1I1,MECOM,ABLIM1,RSL24D1,BNIP1,RALGPS2,FRY,CNTN4,PIK3AP1,SRGAP1,GRIP1,ZNF518B,AGL,LRP12,CHRM3,QSOX1,KCNQ3,COL4A4,FASN,ZBBX,PLCB1,C4orf19,ZNF558,TEX15,PLEKHH2,ADAMTS3,LRRIQ3,EMILIN2,MPP2,CLMN,SFMBT1,SMYD3,EPHA3,ST14,ZNF311,PLXNA2,DDR1,ZNF438,KMO,COL25A1,SCRN1,DNAH5,C3orf67,VNN2,TMEM43,SOX21,KCNH5,ADCY1,WNT11,ATP10D,FGFR1,IQCH,LAMB1,FAM149A,PLD5,CTTNBP2,NR3C2,COBL,MID1,FARP1,WDR17,ANKRD13B,CD276,PRSS35,NKAIN2,CREB5,EPHB1,NEDD4,RGS17,AFF2,GAS2L3,ERRFI1,ULBP1,TMC7,SYNPO2,MCF2L2,RAPGEF2,PTPN13,ELOVL3,AK4,RASA3,GUCY1A2,PTPRC,GALNT3,PCDHB7,TERT,AKT3,SVIL,MYOM2,B4GALT7,TLL2,ATP1A3,EXPH5,CACNG3,ACSL1,MVK,TRIM16,ACTL8,PTPN21,ASS1,C20orf194,ITPR2,SYT14,HMCN1,RTN1,SIPA1L2,RPS6KA2,KCNN2,TMEM86A,ANKFN1,TRPC1,COL19A1,TLN2,PTPRE,TLR4,SLIT2,PDGFRB,ITGB7,GPM6A,SLC3A2,COL4A3,ABCC4,ANK2,CR2,RNF44,TMEM132B,SPNS1,KLF12,PIK3C2B,PPARGC1A,MAGI2,STXBP5L,BVES,ELOVL7,SETBP1,GALNT13,ZNF215,FHOD3,PCDHB14,RNF180,ZBTB38,ABCA5,ZNF440,LRP6,LIMCH1,SLCO4C1,PTPRCAP,NOS3,PCDH10,PODXL2,MGAT4B,SLITRK5,PDE8A,PRDM1,KHDRBS2,NEGR1,MAPKAPK2,GRIK4,PLAGL1,HK2,RAI14,PTPRN2,SEMA3A,OSBPL6,NEK10,CFH,XYLT1,HECW2,RHPN2,KIF21B,DENND3,PIBF1,RADIL,DOCK2,PPP1R9A,CYP26A1,COL22A1,SLC22A17,TACC2,PPFIBP1,REEP1,ZNF521,PROS1,GULP1,MET,TMEM56,GLI1,HRASLS,CTH,DPP10,FER,TMEM67,PTPRU,SLC39A8,FGF12,RARRES2,RANBP2,ZNF93,NRG3,PTPRJ,BACH2,TMPRSS9,PTK7,PTPRS,HGF,OR51B5,IL32,GRB14,ARHGEF11,CLGN,REL,NLRP14,MCTP2,TNFSF13B,SSX1,IGF2BP2,SLC35F1,MAP1A,SCN1B,KIAA0319,KIAA0408,IPCEF1,PCK2,IQGAP3,TNFRSF11A,KIAA1211,DUSP1,DLGAP1,USP2,HNF4G,LRRIQ1,GRID1,PRICKLE1,TGDS,PALLD,SMPDL3B,RERE,MAP1B,DOCK7,FAT4,ZNF214,KIF21A,FILIP1,CACNA2D1 |
| 5.432e-07 | -14.43 | ZHAN_MULTIPLE_MYELOMA_MF_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MF_DN | 36 | 15 | 17377 | 1707 |
CREB3L2,MOB1B,NRG3,ALDH2,STXBP6,CCDC110,ESRRG,RAPGEF2,ENAH,SLC22A15,TMEM170B,MOXD1,PRKCA,DKK1,DOCK9 |
| 5.497e-07 | -14.41 | TGATTTRY_V$GFI1_01 | MSigDB lists | TGATTTRY_V$GFI1_01 | 268 | 53 | 17377 | 1707 |
NMNAT3,FN1,OTX1,MSR1,CLSTN2,CADM2,CREB5,NRXN1,NOVA1,SP8,CTNNA2,CHN1,FOXP2,FBXO32,CHRDL1,ZNF521,FAM133A,SLC2A12,NAP1L3,TSPAN9,RIMS2,FGFR4,BDNF,VAV3,GPM6A,MEIS2,CRIM1,FOXN3,AGPAT4,CACNA1E,ESRRG,DEPTOR,SNAP25,ZFPM2,MAP1B,ZIC1,SNCA,EBF1,KPNA3,RASGRF2,EMILIN2,CLMN,TMEM117,SEMA3C,ZBTB20,CAB39L,GRB10,PPARGC1A,MAPK10,HOXB9,MID1,RAB30,MEF2C |
| 5.604e-07 | -14.39 | KIM_MYC_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYC_AMPLIFICATION_TARGETS_DN | 87 | 25 | 17377 | 1707 |
IL17RD,GCA,TMEM67,RAB3B,LCA5,TTC39B,ELOVL7,PLXNA2,DNER,ILDR2,ZNF93,RIMKLB,MARVELD2,GAS2L3,CCDC146,PLEKHG1,PTPRN2,KLF5,MYO6,FNBP1L,CEBPD,ATP2B4,LPP,NKX2-1,GAB2 |
| 5.604e-07 | -14.39 | ELVIDGE_HIF1A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_TARGETS_DN | 87 | 25 | 17377 | 1707 |
VEGFC,QSOX1,MXI1,PDK1,ENO2,ZNF395,VLDLR,BNIP3L,EFNA3,AK4,SFXN3,FAM13A,FAM162A,PGAP1,ISG20,P4HA2,ALDOC,PAM,HK2,AHNAK2,P4HA1,BNIP3,CSRP2,RRAGD,IGFBP3 |
| 5.614e-07 | -14.39 | tube morphogenesis | biological process | GO:0035239 | 622 | 98 | 17256 | 1658 |
AMOTL1,ACVR1,ID1,LGR4,ST14,ARHGAP22,GATA3,COL18A1,PRKCA,DDR1,SKI,TYMP,TGFBR3,SETDB2,DACT1,ITGB3,DAB2IP,MET,SLIT2,PRKACB,PDGFRB,GLI1,NKX2-1,CYP1B1,FZD1,CEMIP2,KLHL3,ADM2,FZD4,YAP1,WNT11,ACVR2B,JAM3,FGFR1,WARS,GJC1,SMAD3,HPSE,CCBE1,PTK7,APELA,RBPMS2,HPGD,KLF5,BMPR1A,UNC5B,NRP1,COBL,HEY1,MEF2C,EFNB2,CELSR1,BMPR2,FN1,FZD8,OVOL2,SLC12A6,EPHB1,MYC,LRP6,TSPAN12,LOXL4,SPRY2,SYK,NOS3,FGFR4,PAK1,EPB41L5,VEGFC,MICAL2,ATP5IF1,VAV3,KDM5B,SH2D2A,NR4A1,DCHS1,CALCRL,RYR2,PRICKLE1,PRDM1,ZFPM2,HOXA1,LEPR,GPLD1,HEG1,FAT4,EDA,PRCP,CSF1,XBP1,EGFL7,HOXD13,BMP4,SHOX2,CDH2,FOXA1,BTRC,SIX2 |
| 5.670e-07 | -14.38 | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | 186 | 41 | 17377 | 1707 |
BCL11B,SIDT1,IL15,TSPAN15,NOTUM,FAM198B,SPATS2L,SFXN3,FAM174B,DDR1,SATB1,TTC30B,BEX2,EPB41L3,RALGPS2,PCBP4,RASD2,TMEM143,FIG4,MYO6,MORN4,PTPRE,EPB41L5,EBPL,TMTC4,SPATA13,PRDM1,ACVR2B,ZDHHC14,SMPDL3B,RERE,EBF1,HLF,PRKCB,OSBPL5,RGS10,PTPRS,OXTR,DBP,SLC1A5,ABCG1 |
| 5.670e-07 | -14.38 | GSE10325_CD4_TCELL_VS_BCELL_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_UP | 186 | 41 | 17377 | 1707 |
BCL11B,SERINC5,TNIK,ACVR1,RNF144A,ITGA6,GATA3,STAT5B,SPATS2L,PRKCA,NELL2,TGFBR3,BNIP3,IPCEF1,PDE4D,RCAN3,STXBP1,RASGRP1,PRKACB,MICAL2,PXN,TMEM43,SH2D2A,STAT4,SLC39A8,PTPN13,PHACTR2,PRKCQ,VIM,SKAP1,DEXI,NACC2,RGS10,HPGD,SVIL,APBA2,TBC1D4,MLLT3,ATP2B4,STOM,DOCK9 |
| 5.931e-07 | -14.34 | GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 1723 | 229 | 17377 | 1707 |
ARHGAP26,ACSL1,FGF13,GATA3,NPM1,CTBP2,DOCK3,PRKCA,FAM13A,SNX9,NOS1AP,F3,SKI,ARHGEF10L,ADPRHL1,SIPA1L2,AKAP7,PMAIP1,ITGB3,SERINC2,PCOLCE2,TLR4,TSHR,ENO1,RAPGEF5,RASGRP1,PRKACB,PDGFRB,TBC1D8,COL4A3,ACVR1C,TGFA,CAP2,ANK2,LRRK2,ELMOD1,PRKAR2B,ACVR2B,FGF17,SAV1,SGK2,SERGEF,ARHGEF26,GSN,GPRC5B,NCKAP1L,PLK2,RASGRF2,ERN1,ADRB1,ARHGAP28,BBC3,DIRAS1,PPARGC1A,NRP1,TPM1,MAGI2,NEUROG2,MEF2C,RGS16,FN1,ALOX5AP,STXBP5L,TBC1D1,ITGA6,OPHN1,ZIC2,PFN2,CHN1,RALGPS2,CACNB2,MYC,PRELID1,SRGAP1,LRP6,ADCY6,NCAM1,DENND1C,GFRA1,NOS3,EPB41L5,FGFR4,PAK1,MID2,TBC1D8B,RAPGEF4,VLDLR,ARID5B,SPATA13,DUSP9,RYR2,HIP1,STRADB,OBSCN,ARRDC4,PLCB1,FAM162A,HERPUD1,TBC1D2,MAPKAPK2,MMP15,CSF1,IQSEC2,FNBP1L,TESC,DOCK9,BTC,NEK10,AVPI1,RASAL2,AKAP5,DOCK1,GPR65,ARHGAP22,RGS20,ADD2,CHUK,NTRK3,LCP2,DENND3,PIBF1,DOCK2,TBC1D30,PPP1R9A,TIAM2,TBC1D19,TLR3,CDC14B,DACT1,DAB2IP,MARCKS,SYNGR3,HSPA2,DOCK8,PERP,CTH,FZD1,IGFBP3,FER,FZD4,PFKFB2,ADCY1,PREX1,PRKCQ,GSTO1,WNT11,ATP1B1,CD40,DOCK5,TBC1D16,ASPH,FGFR1,SNCA,SMAD3,IRS2,ARHGAP21,NRG3,TRIM34,PRKCB,WFS1,ITGA2,PLEKHG1,RGS10,DUSP19,TNFSF15,HGF,MAPK10,DENND5B,TNIK,SERINC5,LPAR2,FARP1,EDA2R,ARHGEF11,FZD8,PSD3,GAS6,RGS7,PKN1,TPD52L1,ARHGAP44,SYDE2,NKX6-1,RGS17,CHN2,MCF2L,GHR,PRKCD,SGK3,RALGAPA2,SGK1,AFAP1L2,IQGAP3,ERRFI1,TBC1D9,TNFRSF11A,SPRY2,SYK,RIN2,VAV3,ARAP2,GSTM2,MCF2L2,RAPGEF2,CYTH3,ASAP3,RASA3,AGAP2,ARHGAP32,TLR6,GPLD1,PTPRC,TRIB3,SUGT1,FGR,DOCK7,TERT,MAP2K6,GNAO1,ACER2,GRIN2D,BMP4,TBC1D4,MMP16,DOCK6,FOXA1,BTRC,CACNA2D1,ATP2B4 |
| 5.972e-07 | -14.33 | regulation of cell differentiation | biological process | GO:0045595 | 1762 | 229 | 17256 | 1658 |
ACVR1,FGF13,TRIM16,LDLR,LILRB1,GATA3,STAT5B,CEBPA,PRKCA,RAC3,NCS1,STK24,TRPS1,SKI,RND2,EOMES,GRHL1,RAP2A,ITGB3,CTTN,PACSIN1,TLR4,SLIT2,IL1RAP,RASGRP1,NKX2-1,DBN1,GCNT2,MEIS2,DCC,LRRK2,YAP1,FEZ1,AGO4,ACVR2B,SAV1,PLEKHB1,ENPP1,GPRC5B,INSIG1,MAP2,NCKAP1L,PLK2,TNFRSF1A,SEMA3C,SERPINI1,INPP5F,DLX2,NRP1,TNFSF4,SPART,MAGI2,MEF2C,BCL11B,EFNB2,UST,RUNX2,FN1,LGALS3,PTPRD,ZHX3,JDP2,UBASH3B,CHADL,SPINK5,FOXG1,EFEMP1,CHN1,NUMBL,CA2,CNTN4,SEMA4F,ABCA5,GATA2,MYC,C1QL4,PRELID1,GRIP1,ADCY6,TOX,ZNF385A,RIMS2,EPB41L5,PAK1,PTCH2,FADS1,BDNF,DISC1,PNP,MSTN,VLDLR,EFNA3,MAFB,SMARCD3,PRDM1,SNAP25,SDK1,PLCB1,BAIAP2,NEGR1,RIPOR2,ADGRB3,HEYL,CSF1,CDH2,SEMA3A,TESC,SIX2,SHTN1,SFN,EPHA3,PRKN,NBL1,BTC,DNM3,ID1,ZSWIM5,DOCK1,IL15,RBFOX2,PLXNA2,MSR1,HECW2,PKP2,NTRK3,BCL6B,PPP1R9A,SEMA6A,CTNNA2,SCIN,CD53,TLR3,BCL6,ACVR2A,DAB2IP,ZNF488,ZNF365,SNAI2,GLI1,CTH,IGFBP3,FZD1,PHLDB2,PRAME,SSH3,MYLK3,FZD4,PTPN6,NKX3-2,SHANK2,PREX1,VIM,PRKCQ,RARRES2,ATOH1,AMIGO1,DOCK5,FGFR1,SMAD3,CXCL10,NRG3,IKZF3,PRKCB,GBP1,RBPMS2,PTK7,WWTR1,PTPRS,HGF,KLF5,BMPR1A,COBL,CNTN1,HEY1,TNIK,ROBO2,BMPR2,PLAG1,APBB1,LRP4,GAS6,OVOL2,EPHB1,ZNF219,GDPD5,BMP6,NEDD4,ARHGAP44,HOPX,NKX6-1,SCN1B,BHLHA15,KIAA0319,TFAP2A,SH3PXD2B,FIG4,ERRFI1,GFI1,TESPA1,SYK,SLC45A3,ZFP36L2,SPRY2,FES,PDLIM7,TRPM4,VEGFC,LZTS3,MSX1,RAPGEF2,PRICKLE1,ZFPM2,MAP1B,DKK1,CEBPB,TRIB3,ID3,DOCK7,MYADM,FAT4,TERT,FBN1,CTSV,XBP1,BMP4,SHOX2,DDIT3,FOXA1,ABCG1 |
| 6.079e-07 | -14.31 | lung | COSMIC cancer mutations | lung | 16793 | 1672 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTC30A,TTYH2,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,FAM27C,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 6.118e-07 | -14.31 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | 341 | 63 | 17377 | 1707 |
PRKAA2,NBL1,CCDC148,ST14,PTPRD,AKAP5,STXBP6,FHDC1,CYP4V2,SPATS2L,TNFRSF10C,SLC2A13,SLC12A6,NDFIP2,SEL1L3,FAM110B,PCLO,CDS1,RND2,FOXP2,RPS6KA2,TGFBR3,CNTN4,GRHL1,CNKSR3,CACNB2,KAZN,PPFIBP1,RUNDC3B,OPN3,SERINC2,MAP7,CCDC122,SAMD13,MET,VWA5A,GATM,SLIT2,RBMS2,FZD1,EPB41L5,TMEM43,SLC39A8,LRRK2,NFIA,PRICKLE1,PHACTR2,PLS1,SATB2,FNDC3A,GPC6,TPK1,BCL11A,GALNT3,MMP15,IQCH,VPS37D,FAT1,CLDN12,DYNC2LI1,COBL,KIF1B,OCLN |
| 6.174e-07 | -14.30 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP | 469 | 80 | 17377 | 1707 |
ACSL1,GRIK2,AKAP5,LDLR,PTPN21,NOVA1,SEMA6A,KREMEN1,CTNNA2,HECTD2,KCNAB1,RTKN2,GULP1,MARCKS,ARL4D,RAPGEF5,NEB,SEMA6C,IGFBP3,TMEM67,CD55,PNRC1,KLHL3,FZD4,SOX21,ADCY1,FGF17,NT5DC2,CA13,BCL11A,CXCL10,MSC,KLF12,CCNA1,RCN3,KLF5,HS3ST3B1,COBL,OR51B5,TYRO3,RGS16,DYRK3,EDA2R,REL,STXBP6,ELOVL7,NLRP14,GALNT13,BTBD9,P2RY1,DYNC1I1,HOPX,FOXP2,EFEMP1,CNTN4,SCN1B,MCF2L,SRGAP1,SLC6A15,TBC1D9,ATP2B1,LRP12,IGSF3,PNMA2,HNF4G,RAB6B,BTNL9,RAPGEF2,CYTH3,LITAF,WWC1,FERMT2,MFSD2A,CSF1,SLC2A6,PLD1,GEM,KIF1B,FOXA1,TLL2 |
| 6.189e-07 | -14.30 | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP | MSigDB lists | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP | 154 | 36 | 17377 | 1707 |
EML5,TNIK,SIDT1,PRSS12,RNF144A,ST6GAL1,SLC25A27,SELL,TDRKH,TGFBR3,IGF1R,RALGPS2,MYC,LRP6,ADCY6,IPCEF1,ST8SIA1,RASGRP1,CARD6,EVL,PDK1,KDM5B,RAB6B,WLS,RAPGEF4,PLEKHA1,TTC28,SESN1,ID3,BACH2,RGS10,ZBTB20,RNF122,DIRC2,AMPD1,ABCG1 |
| 6.269e-07 | -14.28 | BOQUEST_STEM_CELL_UP | MSigDB lists | BOQUEST_STEM_CELL_UP | 255 | 51 | 17377 | 1707 |
UST,PLA2G4A,MRC2,CFH,IGFBP6,PTPRD,RECK,GALNT12,UGDH,SETBP1,NOVA1,COL14A1,BBS9,PHLDA2,GAS1,F3,EFEMP1,ABI3BP,CHRDL1,SCRN1,GSTM3,PCOLCE2,PLTP,AGL,PRR16,SLIT2,IGFBP3,COL6A2,MEIS2,ANK2,PTPN13,MAFB,FEZ1,C1R,ROR1,STEAP1,CEBPB,SLC39A14,IRS2,MSC,GSN,PDLIM3,PLAGL1,ITGBL1,FBN1,FAT1,RCN3,SEMA3C,BMPR1A,SHOX2,MME |
| 6.306e-07 | -14.28 | positive regulation of molecular function | biological process | GO:0044093 | 1736 | 226 | 17256 | 1658 |
ARHGAP26,ACSL1,FGF13,GATA3,NPM1,FAM13A,SNX9,STK24,NOS1AP,SKI,F3,ADPRHL1,SIPA1L2,PMAIP1,ITGB3,SERINC2,EPHB6,PCOLCE2,TLR4,TSHR,FANK1,IL1RAP,PRKACB,RASGRP1,PDGFRB,TBC1D8,COL4A3,ACVR1C,ANK2,TGFA,LRRK2,ELMOD1,PRKAR2B,ACVR2B,ROR1,SGK2,SAV1,GSN,GPRC5B,NCKAP1L,PLK2,ERN1,ADRB1,ARHGAP28,BBC3,DIRAS1,TPM1,NRP1,PPARGC1A,MAGI2,NEUROG2,CACUL1,MEF2C,TYRO3,RGS16,ALOX5AP,FN1,STXBP5L,TBC1D1,ITGA6,SLK,OPHN1,ZIC2,DYNC1I1,PFN2,CHN1,IGF1R,CACNB2,MYC,PRELID1,SRGAP1,LRP6,ADCY6,INAVA,NOS3,EPB41L5,PAK1,FGFR4,MID2,BDNF,TBC1D8B,VLDLR,ARID5B,EFNA3,GPSM1,RYR2,DUSP9,STRADB,HIP1,ARRDC4,PLCB1,CLN5,FAM162A,HERPUD1,TBC1D2,MMP15,MAPKAPK2,RIPOR2,ADGRB3,CSF1,TESC,DOCK9,EPHA3,PRKN,NEK10,AVPI1,RASAL2,DOCK1,GPR65,ARHGAP22,RGS20,ADD2,CHUK,NTRK3,LCP2,PIBF1,DDR1,TBC1D30,PPP1R9A,DOCK2,TIAM2,TBC1D19,TLR3,CDC14B,DACT1,DAB2IP,SYNGR3,MET,HSPA2,PERP,DOCK8,CTH,ALG10B,FZD1,FER,PFKFB2,FZD4,ADCY1,PREX1,PRKCQ,WNT11,GSTO1,ATP1B1,CD40,ASPH,TBC1D16,FGFR1,SNCA,SMAD3,RANBP2,ARHGAP21,NRG3,TRIM34,PRKCB,BEX3,ITGA2,MAP3K21,RGS10,DUSP19,TNFSF15,HGF,MAPK10,TENM1,SERINC5,TNIK,LPAR2,EDA2R,ARHGEF11,PAK5,FZD8,GAS6,PKN1,EPHB1,RGS7,TPD52L1,ARHGAP44,SYDE2,NKX6-1,RGS17,LRRC55,CHN2,PRKCD,EHD3,GHR,SGK3,SGK1,RALGAPA2,AFAP1L2,SH3PXD2B,ERRFI1,TBC1D9,IQGAP3,TNFRSF11A,SYK,SPRY2,PARP9,VAV3,RIN2,ARAP2,GSTM2,RAPGEF2,ASAP3,RASA3,AGAP2,ARHGAP32,RACK1,TLR6,GPLD1,DKK1,PTPRC,TRIB3,FGR,DOCK7,EDA,TERT,ACER2,GNAO1,MAP2K6,BMP4,TBC1D4,MAP3K20,MMP16,DDIT3,ATP2B4,CACNA2D1,FOXA1 |
| 6.309e-07 | -14.28 | GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | MSigDB lists | GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 739 | 114 | 17377 | 1707 |
BTC,NBL1,AMOTL1,ACVR1,RHOD,RECK,ATP8A1,PLXNA2,GATA3,PKP2,COL18A1,STAT5B,NTRK3,PRKCA,ABHD6,SEMA6A,STK24,NOS1AP,F3,EPCAM,TGFBR3,ITGB3,RAP2A,BCL6,DAB2IP,PDE4D,MET,SLIT2,SEMA6C,PDGFRB,SNAI2,IGFBP3,GLI1,NKX2-1,CYP1B1,FER,PHLDB2,EVL,GCNT2,PTPRU,ACVR1C,ANK2,WNT11,SYNJ2BP,RARRES2,DOCK5,DSP,JAM3,FGFR1,SMAD3,IRS2,ARMC4,GSN,CXCL10,NRG3,PTPRJ,NCKAP1L,CCBE1,LAMB1,ITGA2,ABI3,SEMA3C,HGF,INPP5F,TMEFF2,NRP1,TPM1,PPARGC1A,MAGI2,HACE1,SEMA6B,SCN5A,LGALS3,BMPR2,FN1,SLK,GAS6,PKN1,PFN2,PHLDA2,PPP2R3A,NKX6-1,EFEMP1,SEMA4F,IGF1R,DSG2,SRGAP1,SGK3,SGK1,RRAS2,FES,VEGFC,TRPM4,PAK1,EPB41L5,UNC5C,RAPGEF2,MPP1,SPATA13,RYR2,PLCB1,CPEB1,GPLD1,PTPRC,FGR,DOCK7,MYADM,PRCP,THBS4,CSF1,MCC,BMP4,PLD1,SEMA3A |
| 6.471e-07 | -14.25 | positive regulation of developmental process | biological process | GO:0051094 | 1333 | 181 | 17256 | 1658 |
ACVR1,LGR4,TRIM16,GATA3,STAT5B,CEBPA,PRKCA,RAC3,F3,RND2,TGFBR3,EOMES,PACSIN1,SLIT2,IL1RAP,RASGRP1,PDGFRB,CYP1B1,GCNT2,YAP1,FEZ1,ACVR2B,SAV1,GPRC5B,HPSE,NCKAP1L,CCBE1,PLK2,BMP1,SEMA3C,SERPINI1,OXTR,DLX2,NRP1,TNFSF4,PPARGC1A,VASH2,MAGI2,MEF2C,EFNB2,RUNX2,FN1,LGALS3,PTPRD,ZHX3,FOXG1,NUMBL,CA2,GATA2,MYC,FLRT3,LRP6,GRIP1,BNIP3,TOX,ZNF385A,RIMS2,NOS3,HMGCR,EPB41L5,PAK1,PTCH2,ENAM,BDNF,DISC1,SLITRK2,PNP,VLDLR,NSD2,SLITRK5,SMARCD3,PLS1,PRDM1,PLCB1,BAIAP2,NEGR1,RIPOR2,ADGRB3,HEYL,CSF1,HK2,CDH2,SEMA3A,TESC,SHTN1,SFN,EPHA3,PRKN,NBL1,BTC,DOCK1,IL15,PLXNA2,MSR1,NTRK3,NRXN1,PPP1R9A,CBLN1,SEMA6A,CTNNA2,CD53,SCIN,TLR3,BCL6,ADGRL1,ACVR2A,DAB2IP,ZNF488,ZNF365,GLI1,CTH,IGFBP3,FZD1,PHLDB2,MYLK3,FZD4,ADM2,SHANK2,PREX1,RARRES2,ATOH1,AMIGO1,CD40,DOCK5,FGFR1,SMAD3,PRKCB,APELA,PTK7,WWTR1,HGF,KLF5,BMPR1A,COBL,CNTN1,WASF3,ROBO2,BMPR2,PLAG1,APBB1,TNFSF13B,CLSTN2,GAS6,OVOL2,ZNF219,EPHB1,GDPD5,BMP6,ADGRB2,NKX6-1,FOXP2,LRRN1,SCN1B,GHR,TFAP2A,SH3PXD2B,FIG4,YBX3,IQGAP3,TESPA1,SYK,FES,TRPM4,PDLIM7,VEGFC,KDM5B,RAPGEF2,RACK1,ZFPM2,MAP1B,DKK1,CEBPB,DDAH1,MYADM,TERT,AKT3,XBP1,MYRF,BMP4,SHOX2,FOXA1 |
| 6.476e-07 | -14.25 | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF | 207 | 44 | 17377 | 1707 |
LATS2,ITPRIP,SYT12,PSD3,TJP1,DENND3,OTUD1,ZBTB38,IGF1R,PPFIBP1,PROS1,FAM84B,NCEH1,FBXL2,IL1RAP,CEBPD,DUSP1,PHLDB2,TMEM67,CD55,NR4A1,RAPGEF2,CRIP2,C3orf52,WWC1,FERMT2,ATF3,FNDC3A,MBNL2,HOXA1,RIMKLB,MYADM,RND3,PLK2,ITGA2,NCOA7,SH3BP4,SEMA3C,DBP,GEM,SEMA3A,COBL,OCLN,FOXA1 |
| 6.584e-07 | -14.23 | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP | 187 | 41 | 17377 | 1707 |
ACSL1,ST14,TBC1D1,ZCCHC24,EPS8,LRRCC1,COBLL1,WDFY4,LACC1,SNX9,PGAP1,TLR3,ZNF438,BACE2,MARVELD2,PRKCD,STXBP1,MAST4,GFRA1,MOB1B,SUSD3,ATL1,PPP1R3D,VAV3,GCA,GPM6A,WLS,LRMP,CAPN5,LRRK2,LDHD,SPATA7,PTPRJ,WFS1,EIF4EBP1,SLCO5A1,HPGD,ZBTB20,SERPINI1,DBP,IL9R |
| 6.786e-07 | -14.20 | E2F3_UP.V1_UP | MSigDB lists | E2F3_UP.V1_UP | 174 | 39 | 17377 | 1707 |
UGT8,PLSCR4,ENO2,LRP4,RASD1,CEBPA,ANKRD18A,ZIC2,CYP26A1,EPB41L3,SLC30A4,SAMD11,REEP1,RAB26,ZDHHC23,KCNS3,ATRNL1,HRK,PCOLCE2,SYNGR3,SEPT3,SMAD6,SNX10,HSPA2,RASGRP1,EML6,SLC27A2,JPH1,ZDHHC14,GPR137C,MMP15,DDAH1,TIFA,GPR160,HPGD,TMOD2,CMPK2,HEY1,RRAGD |
| 7.084e-07 | -14.16 | axon guidance | biological process | GO:0007411 | 233 | 47 | 17256 | 1658 |
BCL11B,EFNB2,ROBO2,CELSR3,KIF5A,PLXNA2,OPHN1,KIF5C,GATA3,ENAH,PRKCA,EPHB1,NRXN1,FOXG1,SEMA6A,DOK5,NEO1,CHN1,CNTN4,SEMA4F,SCN1B,FLRT3,NCAM1,ETV1,SLIT2,GFRA1,SEMA6C,GAB2,NKX2-1,PDLIM7,DPYSL5,BDNF,UNC5C,EVL,DCC,VLDLR,EFNA3,FEZ1,PRKCQ,ATOH1,IRS2,MATN2,GRB10,SEMA3C,UNC5B,NRP1,SEMA3A |
| 7.210e-07 | -14.14 | endometrium-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-endometrioid_carcinoma | 16168 | 1625 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,RAB38,TTC28,METAP1D,FGFR1,IQCK,IQCH,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,RBM11,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 7.278e-07 | -14.13 | transmembrane receptor protein kinase activity | molecular function | GO:0019199 | 83 | 24 | 17224 | 1680 |
EPHA3,FGFR4,TYRO3,ACVR1,BMPR2,CRIM1,ACVR1C,EFNA3,NTRK3,ROR1,ACVR2B,EPHB1,DDR1,FGFR1,EFEMP1,TGFBR3,IGF1R,MAP3K21,ACVR2A,EPHB6,BMPR1A,MET,NRP1,PDGFRB |
| 7.340e-07 | -14.12 | anion binding | molecular function | GO:0043168 | 2747 | 339 | 17224 | 1680 |
ARHGAP26,DOC2A,ACVR1,ATP8A1,TUBE1,BCAN,PRKCA,SNX9,RAC3,AARS,STK24,MOK,TGFBR3,ZFYVE28,DNAH6,RAP2A,RAB26,GSTM3,PACSIN1,PLTP,GLDC,ACVR1C,WISP3,LRRK2,PRKAR2B,ABCC2,ACVR2B,GPC6,GNAI1,ENPP1,PLK2,ATP7B,MAPK13,DIRAS1,NRP1,DNHD1,CRYL1,CARS,GNG12,LATS2,ALOX5AP,SCN8A,SLK,DHCR24,OPHN1,SLC1A3,ADSSL1,CHD5,ADCK1,RUNDC3B,PRKG1,ALPK1,DENND1C,FIGN,MAST4,HMGCR,PNP,MYO10,PLEKHA8,RAPGEF4,FASN,PACSIN3,RYR2,HIP1,CDC42BPA,PLCB1,DHX32,RIMKLB,PKN3,ADAMTS3,THBS4,SQLE,LAPTM4B,SLFN5,TRPC3,GVINP1,ACSM3,PLA2G4A,EPHA3,MTG1,DNM3,RHOD,MYO1B,CHUK,MAPK4,GRK6,DDR1,ZFYVE9,TXNRD3,SPEG,ASNS,KMO,COL25A1,DAB2IP,PDE4D,ARL4D,RAB27B,DNAH5,SNX10,GAB2,MYLK3,GARS,PDK1,PFKFB2,CYB5R2,PANK1,PREX1,ADCY1,NLGN4X,PRKCQ,ATP1B1,RAB38,ATP10D,FGFR1,MAGI3,SNCA,ENTPD1,CXCL10,POPDC3,PRKCB,TDO2,PEMT,MAP3K21,PAM,HPGD,P4HA1,BMPR1A,MAPK10,RAB30,MYO1D,GCAT,ATP9A,ARL2,KIF5C,CBS,GAS6,P2RY1,PKN1,EPHB1,FTCDNL1,SOAT2,MCF2L,SGK3,PRKG2,PHYKPL,DYNC2H1,MYO6,SEPT3,FES,PARP9,PFKFB4,TRPM4,OPLAH,ARAP2,GSTM2,RAB6B,RAPGEF2,AK4,ATP11A,GUCY1A2,TRIB3,ID3,FGR,PLOD2,GNAO1,AKT3,OSBPL5,NEK11,PIP5KL1,HK1,BMP4,LRRK1,CMPK2,ATP2B4,ATP1A3,NMNAT3,ACSL1,MVK,KIF5A,SYT12,JCHAIN,ASS1,ITPR2,ABAT,SYT14,NUP62CL,GSDME,F3,RND2,TUBB4A,RPS6KA2,KCNAB1,AADAT,ABI3BP,TRPC1,CNNM2,PCOLCE2,EPHB6,SLIT2,PDGFRB,RASGRP1,PRKACB,ATL1,TNK2,MARK1,SESN2,ABCC4,CEMIP2,PLEKHA1,ROR1,SGK2,SESN1,GRK3,DYRK1B,AK1,P4HA2,ERN1,PIK3C2B,PXDC1,TC2N,RRAGD,PRKAA2,GPT2,TYRO3,MOCOS,RUNX2,FN1,BVES,RHOBTB1,STXBP6,RIMKLA,RASL11B,PFN2,HSPA12B,EEF2,IGF1R,ABCA5,PDE10A,HS3ST5,ADCY6,SNX7,NOS3,PAK1,FGFR4,RHOQ,MSTN,SLC27A2,GSTM4,PARD3B,OBSCN,STRADB,LDHD,MAPKAPK2,FCHO2,RAB31,HK2,PLD1,PANK3,NEK10,CFH,PLEKHA5,NTRK3,KIF21B,PCLO,DDX60L,CYP26A1,SCIN,RIDA,UNC13B,RPS6KL1,FABP6,MYO3B,ACVR2A,MYH15,MET,CLVS2,HSPA2,CTH,FER,TUBA1A,MVD,FRK,TTLL7,ETNPPL,WARS,TPK1,PTK7,GBP1,ITGA2,PTPRS,SEPT5,MAST1,TENM1,TNIK,DYRK3,BMPR2,PAK5,ARL15,MCTP2,NLRP14,SELL,RASD1,ARHGAP44,TECPR1,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,SH3PXD2B,PCK2,RRAS2,SYK,ATP2B1,PCSK6,MICAL2,RAB3B,NUGGC,CYTH3,OGDHL,NUAK2,FERMT2,MARS,AGAP2,ARHGAP32,PEAK1,LRAT,DDAH1,RND3,FBN1,MAP2K6,FMO4,KIF21A,GEM,MAP3K20,KIF1B,PTGES,ABCG1 |
| 7.381e-07 | -14.12 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_DN | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_DN | 168 | 38 | 17377 | 1707 |
RGS16,RUNX2,TNFSF13B,TJP1,ABHD4,SNX9,PFN2,ASNS,TGFBR3,SOAT2,NDUFB8,MYO3B,ST8SIA1,NCEH1,PRKACB,SH3BP2,EBPL,SKAP2,LITAF,HIP1,FNDC3A,ISG20,GABARAPL1,GALNT3,ENTPD1,XKR9,HPSE,PLOD2,ERN1,INPP4B,ADRB1,RGS10,SQLE,INPP5F,RNF130,SMYD3,SLC16A10,ATP2B4 |
| 7.634e-07 | -14.09 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN | 188 | 41 | 17377 | 1707 |
PRKAA2,PLSCR4,TTC39B,ENO2,PSTPIP2,VAMP8,NDRG2,NRXN1,PRKCA,FAM174B,FAM110B,HSPA12B,RND2,FKBP9,FRY,MARVELD2,DSG2,ITGB3,GHR,PRKG1,NBEA,SLC6A15,SLC16A9,GULP1,MED12L,MID2,PHLDB2,DEPTOR,PALLD,PLCB1,TTLL7,TMEM74,TRIB3,ICA1,INSIG1,KLF12,KIAA0355,PLXDC2,PLD1,NR3C2,PKIA |
| 7.634e-07 | -14.09 | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | MSigDB lists | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | 188 | 41 | 17377 | 1707 |
CREB3L2,PLA2G4A,LONRF1,ALOX5AP,CFH,RHOBTB1,GCAT,PSTPIP2,PTPN21,DDR1,GDPD5,NUDT12,TPD52L1,CDS1,PPM1E,RNF180,TLR3,GRHL1,CDC14B,CACNB2,ACVR2A,WWC2,PTPRE,ETV1,MOB1B,PTPN13,DNAJC6,VLDLR,SHISA2,CD40,ZNF711,ENTPD1,IFT81,CACHD1,DOCK7,LRRK1,IQSEC2,MAPK10,RNF157,CSRP2,RRAGD |
| 7.825e-07 | -14.06 | SENESE_HDAC3_TARGETS_UP | MSigDB lists | SENESE_HDAC3_TARGETS_UP | 464 | 79 | 17377 | 1707 |
SCAMP1,CNTNAP3,GALNT12,MYO1B,LMCD1,FAM198B,PMAIP1,PPFIBP1,ITGB3,BCL6,STEAP3,CTTN,MET,TLR4,IL1RAP,PRKACB,PHLDB2,ANTXR2,CD55,TUBA1A,ABCC4,NR6A1,CYB5R2,ATF3,ROR1,SAV1,ASPH,DCBLD2,SLC7A1,RANBP2,CXCL10,MAP2,ZNF697,GRB10,TNFSF15,TNIK,GNG12,RGS16,CCDC148,FN1,IL32,ITGA6,FZD8,UBASH3B,SCD,SPIRE1,ZBTB38,SLC7A11,OPN3,SLC6A15,NCEH1,TBC1D9,ERRFI1,MYO6,FMNL2,ATP2B1,TRPM4,VEGFC,GPR176,MICAL2,SHISA2,PRDM1,GUCY1A2,MBNL2,LEPR,TMEM154,PLEKHH2,FCHO2,CLDN12,AKT3,PGM2L1,PLD1,GEM,SLFN5,TBC1D4,MMP16,XKR4,PKIA,DCBLD1 |
| 7.888e-07 | -14.05 | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | 100 | 27 | 17377 | 1707 |
VEGFC,QSOX1,MXI1,PDK1,ENO2,ZNF395,VLDLR,BNIP3L,EFNA3,AK4,SFXN3,FAM13A,FAM162A,PGAP1,ALDOC,P4HA2,SRD5A3,PAM,HK2,AHNAK2,P4HA1,BNIP3,LIMCH1,CSRP2,IGFBP3,HEY1,RRAGD |
| 7.936e-07 | -14.05 | cell-cell junction organization | biological process | GO:0045216 | 172 | 38 | 17256 | 1658 |
SORBS1,UGT8,RHOD,ARL2,PKP2,TJP1,CADM2,PRKCA,RASSF8,EPB41L3,NUMBL,GRHL1,MARVELD2,DSG2,POF1B,INAVA,CTTN,TLN2,PERP,SNAI2,CDH26,GJB2,ANK2,FERMT2,NLGN4X,WNT11,SDK1,DSP,GJC1,PATJ,HEG1,SMAD3,MYADM,MPP7,ITGA2,CDH17,CDH2,OCLN |
| 8.036e-07 | -14.03 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN | 118 | 30 | 17377 | 1707 |
EML5,EVL,ALDH2,GLIPR1L1,CRIM1,ST6GAL1,PLAG1,GPSM1,SELL,FAM102B,PRKAR2B,SATB1,TTC28,TNKS1BP1,MAGI3,RERE,SYDE2,DYRK1B,BACH2,IGF1R,DLX6,CNKSR3,PLXDC2,MATN2,ADCY6,HOXD13,EPHB6,ST8SIA1,DYNC2H1,TBC1D4 |
| 8.106e-07 | -14.03 | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | 112 | 29 | 17377 | 1707 |
EPHA3,PLA2G4A,TRIM2,SLC39A8,LRP4,LMCD1,SETBP1,CALCRL,RASL11B,DNER,SESN1,PLCB1,ARHGEF26,MKX,EFEMP1,PDLIM3,PMAIP1,ABI3BP,BCL6,BDH2,BNIP3,KLF9,PROS1,LRRK1,ERRFI1,VWA5A,CEBPD,FILIP1,CYP1B1 |
| 8.299e-07 | -14.00 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_UP | 17 | 10 | 17377 | 1707 |
CEBPB,ATF4,XBP1,STC2,SLC7A5,TUBE1,CHAC1,NCEH1,GRPEL2,DDIT4 |
| 8.404e-07 | -13.99 | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP | 182 | 40 | 17377 | 1707 |
BCL11B,TNIK,IL32,ENO2,SIDT1,ITGA6,KIF5C,KIF21B,PRKCA,CD7,SEL1L3,ABLIM1,NELL2,ABCA5,ALDOC,MCF2L,BNIP3,TOX,NAP1L3,PJA1,PDE4D,PTPRCAP,KLHL3,PRKCQ,PLEKHA1,SKAP1,SESN1,PLEKHB1,GYPC,BACH2,INPP4B,ZBTB20,TBC1D4,NR3C2,MLLT3,SMYD3,PKIA,SLC16A10,SNPH,DOCK9 |
| 8.620e-07 | -13.96 | GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 1086 | 155 | 17377 | 1707 |
ACVR1,LGR4,TRIM16,GATA3,CEBPA,STAT5B,PRKCA,RAC3,F3,RND2,EOMES,PACSIN1,SLIT2,RASGRP1,PDGFRB,CYP1B1,GCNT2,YAP1,FEZ1,ACVR2B,SAV1,GPRC5B,HPSE,NCKAP1L,CCBE1,BMP1,OXTR,NRP1,PPARGC1A,TNFSF4,VASH2,MAGI2,MEF2C,EFNB2,RUNX2,LGALS3,FN1,ZHX3,PTPRD,NUMBL,CA2,GATA2,FLRT3,MYC,LRP6,BNIP3,RIMS2,ZNF385A,NOS3,HMGCR,PTCH2,EPB41L5,BDNF,DISC1,PNP,SLITRK2,VLDLR,SMARCD3,SLITRK5,PLS1,PRDM1,PLCB1,CPEB1,BAIAP2,NEGR1,CSF1,HEYL,CDH2,SEMA3A,TESC,SFN,EPHA3,PLA2G4A,NBL1,BTC,IL15,AKAP5,MSR1,NTRK3,NRXN1,PPP1R9A,CBLN1,SEMA6A,CTNNA2,SCIN,CD53,BCL6,ACVR2A,DAB2IP,MARCKS,ZNF488,SNAI2,GLI1,IGFBP3,CTH,PHLDB2,MYLK3,ADM2,PREX1,ATOH1,RARRES2,AMIGO1,CD40,FGFR1,BCL11A,SMAD3,PRKCB,PTK7,WWTR1,KLF5,HGF,BMPR1A,COBL,CNTN1,WASF3,ROBO2,BMPR2,CD276,PLAG1,APBB1,CLSTN2,GAS6,OVOL2,EPHB1,GDPD5,BMP6,HOPX,NKX6-1,FOXP2,LRRN1,SCN1B,GHR,TFAP2A,SGK1,SH3PXD2B,FIG4,IQGAP3,SYK,FES,TRPM4,PDLIM7,VEGFC,USP2,KDM5B,RAPGEF2,ZFPM2,MAP1B,DKK1,CEBPB,DDAH1,MYADM,XBP1,BMP4,SHOX2,FOXA1 |
| 8.749e-07 | -13.95 | large_intestine-colon-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma-adenocarcinoma | 16933 | 1681 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,CHSY3,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 8.757e-07 | -13.95 | V$PIT1_Q6 | MSigDB lists | V$PIT1_Q6 | 216 | 45 | 17377 | 1707 |
PHACTR3,PCDH18,INPPL1,ACVR1,FGF13,KLHL13,RBFOX2,PLAG1,PRDM8,ARHGAP44,LGI2,FOXP2,CHN2,LHX6,ZNF521,SGK3,MPPED2,ZDHHC23,BEND4,MARCKS,PPP2R2B,TSPAN9,C15orf41,SCN3A,GAB2,PTCH2,BDNF,MEIS2,ESRRG,NPM3,DCHS1,FEZ1,ATP1B1,MBNL2,BCL11A,ENTPD1,ID3,DOCK7,GNAO1,DLG2,NRP1,TPM1,SEMA3A,HOXB9,MID1 |
| 8.838e-07 | -13.94 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP | 189 | 41 | 17377 | 1707 |
CXCR5,TBKBP1,INPPL1,TRIM2,RUNX2,CFH,PRSS12,RHOBTB1,ST14,GCAT,KIF5C,OR51B4,DDR1,HOPX,CPNE2,ASNS,SEC16B,SOAT2,HPS1,ERRFI1,SPRY2,PTPN13,NUAK2,ATF3,AIG1,PDE8A,PRDM1,LHPP,TGDS,CEBPB,CAMK2N1,MSC,ENPP1,NACC2,CLDN12,THBS4,FAT1,NXPH4,DIRAS1,BMPR1A,TTC39A |
| 9.031e-07 | -13.92 | cell junction organization | biological process | GO:0034330 | 200 | 42 | 17256 | 1658 |
SORBS1,UGT8,FN1,RHOD,ITGA6,OPHN1,ARL2,PKP2,TJP1,CADM2,PRKCA,RASSF8,EPB41L3,NUMBL,GRHL1,MARVELD2,DSG2,POF1B,INAVA,CTTN,TLN2,PERP,SNAI2,CDH26,GJB2,ANK2,FERMT2,NLGN4X,TNS1,WNT11,SDK1,DSP,GJC1,PATJ,HEG1,SMAD3,MYADM,MPP7,ITGA2,CDH17,CDH2,OCLN |
| 9.097e-07 | -13.91 | REACTOME_AXON_GUIDANCE | MSigDB lists | REACTOME_AXON_GUIDANCE | 237 | 48 | 17377 | 1707 |
COL9A3,SCN5A,ROBO2,ARHGEF11,DOCK1,SCN8A,PLXNA2,ENAH,COL4A5,CACNB4,PFN2,SEMA6A,NEO1,ABLIM1,RPS6KA2,SCN1B,CACNB2,ITGB3,SRGAP1,MET,SCN2A,NCAM1,SLIT2,GFRA1,COL9A2,FES,DPYSL5,PAK1,UNC5C,EVL,COL6A2,KCNQ3,COL4A3,DCC,MYO10,COL4A4,CAP2,PRKCQ,FGFR1,PTPRC,SH3GL2,ITGA2,LAMB1,UNC5B,NRP1,SEMA3A,TRPC3,CNTN1 |
| 9.147e-07 | -13.90 | neuron projection guidance | biological process | GO:0097485 | 235 | 47 | 17256 | 1658 |
BCL11B,EFNB2,ROBO2,CELSR3,KIF5A,PLXNA2,OPHN1,KIF5C,GATA3,ENAH,PRKCA,EPHB1,NRXN1,FOXG1,SEMA6A,DOK5,NEO1,CHN1,CNTN4,SEMA4F,SCN1B,FLRT3,NCAM1,ETV1,SLIT2,GFRA1,SEMA6C,GAB2,NKX2-1,PDLIM7,DPYSL5,BDNF,UNC5C,EVL,DCC,VLDLR,EFNA3,FEZ1,PRKCQ,ATOH1,IRS2,MATN2,GRB10,SEMA3C,UNC5B,NRP1,SEMA3A |
| 9.222e-07 | -13.90 | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 176 | 39 | 17377 | 1707 |
PRSS16,IGFBP6,BMPR2,ATP9A,KIF5A,ZNF25,XYLT1,PTPN21,RASD1,TTC30B,CYP26A1,RTN1,PCDHB14,OTUD1,EHD3,REEP1,TSC22D1,NAP1L3,MPDZ,FIG4,RAB27B,PRKACB,CEBPD,DUSP1,KDM5B,RAB6B,MGST3,GDPD1,BNIP3L,AIG1,CTTNBP2NL,WARS,ZNF711,BEX4,MYADM,RND3,CCNA1,NCOA7,PGM2L1 |
| 9.358e-07 | -13.88 | colon | COSMIC cancer mutations | colon | 16934 | 1681 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,CHSY3,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 9.431e-07 | -13.87 | CAGCTG_V$AP4_Q5 | MSigDB lists | CAGCTG_V$AP4_Q5 | 1407 | 192 | 17377 | 1707 |
DOC2A,ACVR1,FGF13,VAMP8,GATA3,ASS1,STAT5B,CADM2,CHAC1,ABHD4,IKZF2,NOVA1,HECTD2,CCNJ,PLS3,TUBB4A,PPM1E,RUFY4,EOMES,KCNN2,TMEM86A,RAB26,MPPED2,KCNS3,CNNM2,JAKMIP2,BEND4,VWA5A,ETV1,NEB,MEIS2,KCNIP3,ANK2,JPH1,DEPTOR,TNS1,FGF17,SGK2,KLF12,RASGRF2,ERN1,B3GALT2,BMP1,ZBTB20,SPRY4,DNHD1,TNFSF4,APBA2,FRMD5,RRAGD,MEF2C,BCL11B,LONRF1,PRKAA2,LRFN5,SCN5A,KLF8,INPPL1,STXBP6,ITGA6,ZCCHC24,ATP6V1E2,SORBS3,APBA1,TNFRSF19,SPINK5,DDIT4,NUMBL,ABLIM1,NAV1,CNTN4,IGF1R,SLC7A11,PIK3AP1,BACE2,CACNB2,FLRT3,FRAS1,MYC,PDE10A,BNIP3,LOXL4,ZNF385A,PTCH2,NDUFA4L2,MID2,MSTN,SPATA6,PACSIN3,WDR25,SLITRK5,OBSCN,HIP1,RABAC1,MBNL2,BAIAP2,NAP1L5,RPL28,MFSD2A,NXPH4,DOCK9,CXCR5,ID1,SORBS1,RHOD,RBFOX2,BCL6B,MAPK4,DDR1,TNKS1BP1,SPEG,COL22A1,SLC22A17,UNC13B,DACT1,REEP1,BCL6,ZNF521,NBEA,SCRN1,JAKMIP3,MYT1,GAB2,IGFBP3,TUBA1A,PTPN6,PRDM13,FGF12,PRKCQ,FBXO36,TTLL7,BACH2,PRKCB,PTK7,PAM,PTPRS,KLF5,NR3C2,MID1,RAB30,PCDH18,MXI1,IGFBP6,BMPR2,GCAT,CD276,CLSTN2,PRDM8,RGS7,BMP6,BEX2,ARHGAP44,PPP2R3A,NEDD4,MAP1A,LRRN1,PCBP4,GHR,KCNMB3,PRICKLE2,IPCEF1,GFI1,SEPT3,FES,DUSP1,DLGAP1,TRPM4,PPP1R3D,BCL7A,NR4A1,ESRRG,CYTH3,CRIP2,PRICKLE1,AGAP2,ID3,FGR,MYADM,MAP2K6,XBP1,SRD5A3,SVIL,GRIN2D,DLG2,LRRK1,GEM,SHOX2,DOCK6,KIF1B,FOXA1,FILIP1,SNPH |
| 9.470e-07 | -13.87 | rhabdomyosarcoma | COSMIC cancer mutations | rhabdomyosarcoma | 4239 | 496 | 17385 | 1698 |
ARHGAP26,DOC2A,MYCBP2,CGN,TCP11L2,SIDT1,GRIK2,PRSS12,DNAJC3,LDLR,NPM1,CTBP2,CEBPA,AARS,RAC3,SKI,TRPS1,EPDR1,BAG3,TGFBR3,DNAH6,PPFIA2,RAB26,KCNS3,GSTM3,ATRNL1,BEND4,PPP2R2B,RCAN3,TSHR,TBC1D8,EML6,ACVR1C,DCC,KLHL23,KLHL4,LRRK2,NFIA,EFHC1,ABCC2,ZDHHC14,GPR150,ENPP1,PLK2,ADRB1,MAPK13,ERCC5,DSEL,TANC2,DNHD1,SPOCK3,LZTS1,SCN5A,TMEM63C,LATS2,INPPL1,FAM124A,ALOX5AP,CELSR1,ZHX3,TBC1D1,CYP2J2,ITGA6,ZNF25,TJP1,SLC1A3,WDFY4,MTUS1,NAV1,KIAA1671,PDZD7,FAM189A1,FLRT3,ZIC5,VWDE,OPN3,MPDZ,CADPS2,LMAN2,TSPAN12,ALPK1,LOXL4,MOXD1,ZNF518B,AGL,GLIS1,FMNL2,RIMS2,HMGCR,IGSF3,SLC37A1,PNP,KCNQ3,MYO10,COL4A4,ARID5B,DCHS1,FASN,KIAA1324L,RYR2,TTC30A,TTYH2,HIP1,SMARCD3,C1R,PEX5L,CCDC85A,CDC42BPA,CLN5,TMEM74,DAGLA,TEX15,VPS37D,GSTO2,PMEPA1,ADAMTS3,THBS4,CECR2,EMILIN2,CDH17,SLFN5,CDH2,AMPD1,DOCK9,PLA2G4A,TBKBP1,AMOTL1,ZNF516,ELOVL4,RNF144A,GALNT12,FAM131C,ZNF311,MYO1B,LRRCC1,MSR1,RGS20,OTX1,ADD2,PKP2,CHUK,KCTD12,COLEC10,TBC1D30,TIAM2,NELL2,SPEG,ZNF827,TLR3,CHRNA5,GPRIN1,KMO,POU5F1B,ALDH1L1,SCRN1,NBEA,RTKN2,DNAH5,MYT1,SCN3A,DOCK8,FZD1,GAB2,GARS,COL6A2,GAPDH,NKX3-2,KCNH5,NLGN4X,SATB2,WNT11,PRKCQ,PYGO1,ATOH1,TTC28,DSP,ATP10D,FGFR1,MAGI3,DCBLD2,ENTPD1,PRKCB,WFS1,LAMB1,MAP3K21,PAM,PLEKHG1,KLF5,FAM149A,KLHL31,LRRC27,COBL,PURG,HACE1,CGB2,ANKRD13D,TMEM132C,WDR17,ROBO2,CD276,ESRP1,ARL2,GABRR2,INPP1,BEX2,COL27A1,NEDD4,NEO1,LRRC55,MGAT1,GPR155,RALGAPA2,MORN2,FIG4,MYO6,NPTXR,SMAD6,GFI1,MED12L,PARP9,MN1,BCL7A,VAV3,ARAP2,CACNA1E,MCF2L2,PTPN13,UCHL3,HEG1,CEBPB,ZFP62,PTPRC,NSD1,PLOD2,TERT,XBP1,MYOM2,TNFRSF17,DOCK6,ATP2B4,OCLN,FOXA1,PHC1,MVK,ACSL1,TRIM16,KIF5A,SYT12,FHDC1,LILRB1,SLC2A13,FAM13A,DNER,HMCN1,FKBP11,CCNJ,RTN1,ARHGEF10L,LGI2,CYP51A1,PPM1E,SIPA1L2,TM9SF2,EOMES,CPVL,SEC16B,LRRC6,HPS1,ANKFN1,ITGB3,TMEM143,JAKMIP2,KIAA1614,SLC2A12,TLN2,TLR4,IL1RAP,NEB,PDGFRB,CYP1B1,MARK1,CD55,ABCC4,PNRC1,COL4A3,SPOCD1,ANK2,CAPN5,JPH1,YAP1,CR2,PLEKHA1,CRYBG3,SERGEF,EML1,TSKU,DYRK1B,FHAD1,TMEM132B,GSN,TCF7L1,HPSE,ITGBL1,NCAM2,MAP2,P4HA2,ERN1,TNFRSF1A,PIK3C2B,OXTR,PPARGC1A,APBA2,NEUROG2,MAGI2,TC2N,MOCOS,STXBP5L,LGALS3,FN1,OTOGL,SCART1,LAMC3,SCD,GALNT13,PFN2,MLC1,SPINK5,CD7,FHOD3,NUMBL,KIAA0895,ZBTB38,IGF1R,BCHE,ZNF440,FRAS1,PDE10A,EBF4,GAN,SMTN,LRP6,ADCY6,VGLL4,LRP3,NOS3,ZNF629,FGFR4,DPYSL5,CDH26,IL17RD,HBG2,PCDH10,PODXL2,SLITRK2,SH2D2A,MSTN,PARD3B,EFNA3,TMTC4,SPATA13,EDEM3,SDC3,WWC1,OBSCN,SLITRK5,PDE8A,PRDM1,SDK1,B4GALNT3,HEYL,FAT1,HK2,PTPRN2,PLD1,DISP2,XKR4,MME,CXCR5,DMXL2,EML5,ZSWIM5,ID1,SORBS1,DOCK1,CELSR3,HECW2,MORC4,COL18A1,COBLL1,NTRK3,ZNF83,SLC7A2,CANX,DENND3,RADIL,DDX60L,PCLO,CYP26A1,FAM131B,COL22A1,PDZD8,SLC22A17,UNC13B,TACC2,EEPD1,BCL6,STEAP3,MYH15,WWC2,MET,SCN2A,ZNF460,NTNG1,SEMA6C,SP140L,IGFBP3,FER,CSN2,TMEM65,SLC39A8,PTPN6,THSD4,TES,ACO1,RNF125,GSTO1,VIM,AMIGO1,DOCK5,CENPV,C4BPB,ARMC4,PTPRJ,PTK7,TMPRSS9,ITGA2,MAOA,HGF,DISP1,CTNND2,TENM1,COL9A3,DYRK3,BMPR2,KLHL13,ARHGEF11,GRB14,RUSC2,LRP4,NSUN6,COL4A5,NOTUM,CUEDC2,SEL1L3,TECPR1,MAP1A,SCN1B,TFAP2A,KIAA0319,TSC22D1,PRICKLE2,TSPAN13,DHRS12,KIAA0408,IQGAP3,KIAA1211,CES3,USP2,LRRIQ1,CRIM1,NR4A1,ESRRG,SYBU,LITAF,ASAP3,MEI1,PRICKLE1,AGAP2,ZFPM2,NPDC1,LEPR,MGMT,SMPDL3B,RERE,EBF1,ADAMTS17,DOCK7,FAT4,FBN1,NACC2,THSD7B,ZNF474,KIF21A,TBC1D4,PTGES,MMP16 |
| 9.676e-07 | -13.85 | integral component of plasma membrane | cellular component | GO:0005887 | 1670 | 215 | 18223 | 1724 |
ACVR1,CACNG3,LGR4,GRIK2,LDLR,CADM2,SLC2A13,ABHD6,SLCO3A1,NOS1AP,PCDH7,EPCAM,TGFBR3,TM9SF2,KCNAB1,HPS1,SLC16A2,ITGB3,KCNS3,TRPC1,SLC2A12,CTTN,EPHB6,TLR4,TSHR,IL1RAP,PDGFRB,ITGB7,CD55,KCNIP3,ABCC4,CEMIP2,ACVR1C,TGFA,LRMP,PLPP2,ABCC2,ACVR2B,KCND3,ROR1,GPC6,SLC7A1,ENPP1,TMEM150B,KCNMB4,NCKAP1L,ATP7B,TNFRSF1A,ADRB1,OXTR,TNFSF4,TYRO3,EFNB2,KCNV1,SEMA6B,SCN5A,MRC2,CELSR1,PTPRD,GABRB2,SCN8A,ITGA6,SLC1A3,TNFRSF10C,PCDHB14,IGF1R,SEMA4F,SLC7A11,CACNB2,FLRT3,OPN3,TSPAN12,LMAN2,SLC16A9,SLCO4C1,JAM2,TSPAN9,LRP12,CHRM3,FGFR4,IL17RD,GPR176,PCDH10,PODXL2,KCNQ3,EFNA3,CALCRL,SNAP25,OR11H4,GPR19,STEAP1,MMP15,GRIK4,KCNK15,MFSD2A,FAT1,SLC2A6,MPP2,PTPRN2,CDH2,TRPC3,MME,CXCR5,EPHA3,SORBS1,IL15,ST14,GPR65,PLXNA2,MSR1,NTRK3,IL13RA1,CHUK,SLC7A2,NRXN1,DDR1,SEMA6A,CD53,GPR15,PLPP1,TLR3,SLC22A17,CHRNA5,COL25A1,ACVR2A,STEAP3,SCN2A,MET,PERP,SEMA6C,KCNB2,SCN3A,DPP10,PTPRU,FZD4,KCNH5,SLC39A8,SHANK2,ADCY1,NLGN4X,CHRNA6,AMIGO1,ATP1B1,CD40,FGFR1,DCBLD2,HTR7,ENTPD1,SLC39A14,NRG3,PTPRJ,GYPC,PTK7,TMPRSS9,KCNG1,ITGA2,ASIC1,MAP3K21,PTPRS,TNFSF15,HS3ST3B1,LIFR,TENM1,PCDH18,LPAR2,SLC6A9,BMPR2,EDA2R,TSPAN15,BACE1,SELL,GABRG2,GABRR2,SLC12A6,P2RY1,EPHB1,SLC35G2,KCNC4,TSPAN17,NEO1,LRRC55,KCNJ4,SCN1B,GHR,KCNMB3,TSPAN13,SLC6A15,TNFRSF11A,ATP2B1,TRPM4,SLC40A1,RAPGEF2,MPP1,PRRG1,TLR6,GPR37,PTPRC,CD37,EDA,PCDHB7,PLPPR2,SLC7A5,SLCO5A1,SLC18B1,GRIN2D,DLG2,SLC22A15,SLC1A5,IL9R,MMP16,SLC16A10,ATP2B4,ATP1A3,SLC43A1,STOM |
| 9.795e-07 | -13.84 | actin cytoskeleton organization | biological process | GO:0030036 | 461 | 77 | 17256 | 1658 |
ARHGAP26,AMOTL1,SORBS1,TMSB15A,RHOD,GPR65,MYO1B,COBLL1,ADD2,RAC3,PPP1R9A,DOCK2,PLS3,SCIN,ARHGEF10L,RND2,EPB41L3,RAP2A,BCL6,POF1B,RTKN2,MARCKS,CTTN,PACSIN1,PDGFRB,DBN1,FER,EVL,MYLK3,CAP2,DSTN,PREX1,GSN,WIPF3,NCKAP1L,PTK7,ALDOA,TMOD2,TPM1,NRP1,COBL,FRMD5,WASF3,TNIK,INPPL1,ARHGEF11,PAK5,RHOBTB1,EPS8,OPHN1,SORBS3,PFN2,SPIRE1,FHOD3,FRY,GAS2L3,PRKG1,LIMCH1,FMNL2,EPB41L5,PDLIM7,PAK1,MICAL2,RHOQ,NUAK2,HIP1,OBSCN,PLS1,CDC42BPA,PALLD,BAIAP2,RND3,FAT1,MYOM2,IQSEC2,NPHP1,SHTN1 |
| 9.806e-07 | -13.84 | COLDREN_GEFITINIB_RESISTANCE_DN | MSigDB lists | COLDREN_GEFITINIB_RESISTANCE_DN | 210 | 44 | 17377 | 1707 |
EXPH5,FAM171B,MPZL3,CGN,MYO1D,ST14,RHOD,CYP2J2,VAMP8,BIK,COBLL1,OVOL2,DDR1,IKZF2,PRRG4,CDS1,RNF141,GRHL1,PRKCD,SLC2A12,FAM84B,MYO6,VAV3,GCA,ARAP2,GCNT2,TBC1D8B,WLS,TTC22,AIG1,RAB38,MFSD6,SMPDL3B,GALNT3,KCNMB4,MPP7,GPR160,C1orf21,SVIL,SH3BGRL2,MAPK13,TC2N,FOXA1,OCLN |
| 1.002e-06 | -13.81 | CHYLA_CBFA2T3_TARGETS_DN | MSigDB lists | CHYLA_CBFA2T3_TARGETS_DN | 217 | 45 | 17377 | 1707 |
CREB3L2,TRIM2,SORBS1,DUSP8,TSPAN15,HEBP1,MLF1,BLVRB,FHDC1,LMCD1,GPSM2,SEMA6A,PHLDA2,EYA4,SPIRE1,CHST10,EPDR1,KIAA0895,ASNS,KCNAB1,MARVELD2,SAMD11,FHIT,TMEM56,IGSF3,MYLK3,SESN2,AGPAT4,MGST3,SLC39A8,GDPD1,HOMER2,NFIA,TNS1,SLC46A3,TEX9,CENPV,ISG20,MFSD9,P4HA2,ATP7B,KLF5,TTC39A,MBOAT2,BTRC |
| 1.025e-06 | -13.79 | GO_PLASMA_MEMBRANE_REGION | MSigDB lists | GO_PLASMA_MEMBRANE_REGION | 895 | 132 | 17377 | 1707 |
GRIK2,LDLR,NCS1,NOS1AP,EPCAM,AKAP7,SLC22A18,MARVELD2,ITGB3,CNNM2,LIN7A,PACSIN1,MYRIP,CPE,PDGFRB,SLC3A2,ATF4,ABCC4,WLS,ANK2,TGFA,LRRK2,ABCC2,PLEKHA1,ENPP1,ATP7B,OXTR,SPRY4,TPM1,LZTS1,SCN5A,FN1,BVES,GABRB2,ITGA6,TJP1,SLC1A3,MLC1,BBS9,CA2,SEMA4F,FLRT3,LRP6,ADCY6,GRIP1,CADPS2,MPDZ,SLCO4C1,RIMS2,GPR161,CHRM3,NOS3,PAK1,EPB41L5,DISC1,MYO10,HOMER2,SPATA13,WWC1,SNAP25,CPEB1,GRIK4,CDH17,PLD1,CDH2,TESC,AMOTL1,TCTN2,AKAP5,ST14,KCTD12,LCP2,NRXN1,PRR7,DDR1,CBLN1,CTNNA2,EPB41L3,CHRNA5,MAP7,PDE4D,RAB27B,MET,TMEM67,SHANK2,CHRNA6,NLGN4X,ATP1B1,DSP,GABARAPL1,CAMK2N1,PTPRJ,PEMT,HPGD,BMPR1A,TNIK,MYO1D,ROBO2,BMPR2,APBB1,EPS8,LRP4,CLSTN2,PSD3,GABRG2,P2RY1,SLC12A6,GABRR2,NEDD4,KCNJ4,EHD3,DSG2,PRKG2,MYO6,SPRY2,ATP2B1,DLGAP1,SLC40A1,RAPGEF2,GRID1,FERMT2,ARHGAP32,LEPR,HOMER3,FGR,SLC7A5,DLG2,GRIN2D,OCLN,SLC16A10,ATP2B4,SNPH |
| 1.028e-06 | -13.79 | DHR-2 | pfam domains | PF06920 | 11 | 8 | 17054 | 1666 |
DOCK7,DOCK3,DOCK5,DOCK1,DOCK2,DOCK6,DOCK8,DOCK9 |
| 1.028e-06 | -13.79 | DOCK-C2 | pfam domains | PF14429 | 11 | 8 | 17054 | 1666 |
DOCK7,DOCK3,DOCK5,DOCK1,DOCK2,DOCK6,DOCK8,DOCK9 |
| 1.029e-06 | -13.79 | Collagen biosynthesis and modifying enzymes | REACTOME pathways | R-HSA-1650814 | 70 | 21 | 10287 | 971 |
COL9A3,COL6A2,COL4A3,COL4A4,COLGALT2,COL18A1,COL4A5,COL14A1,COL27A1,COL22A1,PLOD2,ADAMTS3,COL25A1,P4HA2,BMP1,P4HA1,COL19A1,PCOLCE2,SERPINH1,COL9A2,TLL2 |
| 1.049e-06 | -13.77 | DHR-1_domain | interpro domains | IPR027007 | 11 | 8 | 18492 | 1811 |
DOCK7,DOCK1,DOCK3,DOCK5,DOCK6,DOCK2,DOCK8,DOCK9 |
| 1.049e-06 | -13.77 | DOCK | interpro domains | IPR026791 | 11 | 8 | 18492 | 1811 |
DOCK7,DOCK1,DOCK3,DOCK5,DOCK6,DOCK2,DOCK8,DOCK9 |
| 1.049e-06 | -13.77 | DHR-2 | interpro domains | IPR027357 | 11 | 8 | 18492 | 1811 |
DOCK7,DOCK3,DOCK5,DOCK1,DOCK2,DOCK6,DOCK8,DOCK9 |
| 1.049e-06 | -13.77 | DOCK_C | interpro domains | IPR010703 | 11 | 8 | 18492 | 1811 |
DOCK7,DOCK1,DOCK3,DOCK5,DOCK6,DOCK2,DOCK8,DOCK9 |
| 1.054e-06 | -13.76 | GO_EPITHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_EPITHELIAL_CELL_DIFFERENTIATION | 452 | 77 | 17377 | 1707 |
EXPH5,TFCP2L1,ACVR1,ID1,ST14,ACTL8,MCOLN3,GATA3,COL18A1,NTRK3,PLS3,DLX6,KAZN,ALDOC,MARVELD2,RAP2A,GSTM3,PDE4D,MET,GLI1,NKX2-1,FZD1,INTU,NKX3-2,CAPN5,YAP1,VIM,WNT11,ACVR2B,ATOH1,SAV1,DSP,FGFR1,ARHGEF26,SMAD3,PTK7,ITGA2,BDH2,PTPRS,KLF5,NRP1,MAGI2,HEY1,MEF2C,BCL11B,LATS2,BMPR2,LGALS3,TJP1,GPSM2,OVOL2,SPINK5,BMP6,NKX6-1,SLC7A11,PDZD7,ACTA2,BARX1,EPB41L5,B9D1,PTCH2,KDM5B,RAPGEF2,PRDM1,FNDC3A,PALLD,MGMT,HEG1,CEBPB,ID3,MYADM,XBP1,BMP4,CDH2,SIX2,FOXA1,SFN |
| 1.072e-06 | -13.75 | regulation of biological quality | biological process | GO:0065008 | 3779 | 441 | 17256 | 1658 |
DOC2A,PDE1B,LGR4,GRIK2,ATP8A1,LDLR,VAMP8,GATA3,NPM1,STAT5B,CEBPA,NHP2,PRKCA,ABHD6,RAC3,AARS,SLC9A7,NOS1AP,TXNDC5,BAG3,TGFBR3,PMAIP1,SLC16A2,PPFIA2,KCNS3,COG3,CPE,POU3F3,GLDC,ACVR1C,DCC,KLHL3,SLC9C1,DSTN,LRRK2,BNIP3L,DEPTOR,SLC25A28,PRKAR2B,ABCC2,KCND3,ACVR2B,F12,SAV1,PYCR1,SFXN1,ENPP1,WIPF3,NCKAP1L,ENPP6,PLK2,ATP7B,ALDOA,BDH2,ADRB1,ARHGAP28,BBC3,SEMA3C,TMOD2,TPM1,NRP1,SPART,MEF2C,SCN5A,PTPRD,GABRB2,SCN8A,SLC25A27,BTBD9,GPSM2,SLC1A3,APBA1,CNTN4,SLC7A11,BACE2,CACNB2,MYC,FLRT3,PRELID1,SREBF1,PRKG1,CADPS2,MOXD1,PRR16,STXBP1,FAM155A,CHRM3,RIMS2,ZNF385A,HMGCR,BDNF,QSOX1,KCNQ3,MYO10,RAPGEF4,RYR2,HIP1,PLS1,NPC2,SNAP25,CLN5,SPATA7,DAGLA,PLEKHH2,MPP2,SELENOM,LAPTM4B,DHCR7,CDH2,TRPC3,SHTN1,ACSM3,DOCK9,NBL1,BTC,DNM3,PCSK1N,TMSB15A,RHOD,GPR65,MSR1,PLXNA2,PKP2,ADD2,NRXN1,LCP2,DDR1,TXNRD3,EPB41L3,NELL2,CHRNA5,KMO,DACT1,STARD4,DAB2IP,MARCKS,PDE4D,FAM155B,ZNF365,DOCK8,SCN3A,SSH3,MYLK3,GAPDH,ADM2,FZD4,PFKFB2,SFXN4,KCNH5,SHANK2,PREX1,ADCY1,NLGN4X,PRKCQ,ATP1B1,RAB38,DSP,ASPH,ATP10D,FGFR1,SNCA,GJC1,IRS2,ENTPD1,SLC39A14,HTR7,CXCL10,ARHGAP21,POPDC3,PRKCB,WFS1,ASIC1,PAM,ATG5,WASF3,MXI1,PLSCR4,C1QTNF3,ROBO2,GCAT,ATP9A,EPS8,ARL2,GAS6,P2RY1,GABRR2,SLC12A6,PKN1,EPHB1,ZNF219,KCNC4,NEDD4,ADGRB2,NEO1,IRX5,LRRN1,SOAT2,PCBP4,BHLHA15,GHR,YBX3,GFI1,ZFP36L2,FES,TRPM4,VEGFC,SLC40A1,LZTS3,VAV3,GSTM2,CACNA1E,RAPGEF2,RASA3,RACK1,ATP11A,HEG1,GPLD1,PTPRC,FGR,TERT,AKT3,XBP1,SRD5A3,GRIN2D,HK1,BMP4,LRRK1,JHY,TNFRSF17,DOCK6,DDIT3,ATP2B4,FOXA1,BTRC,LARP1,TPT1,ATP1A3,CACNG3,FGF13,SYT12,JCHAIN,ASS1,ITPR2,ABAT,SYT14,CACNB4,ABHD4,F3,RND2,KCNN2,GRHL1,ITGB3,TRPC1,LIN7A,CNNM2,CTTN,TLN2,MYRIP,TLR4,SLIT2,NEB,IL1RAP,PRKACB,CYP1B1,DBN1,CD55,GCNT2,SESN2,ANK2,ATOX1,JPH1,NFE2L1,PLEKHA1,TRIM9,GSN,KCNMB4,INSIG1,HPSE,ERN1,OXTR,PPARGC1A,TC2N,SLC9B1,PCSK5,PRKAA2,TYRO3,FN1,STXBP5L,RHOBTB1,BVES,FBXO4,UBASH3B,ATP6V1E2,PHGDH,PFN2,SPIRE1,FHOD3,RNF180,SLC30A4,CA2,IGF1R,SEMA4F,BCHE,GATA2,LRP6,ADCY6,INAVA,BNIP3,NOS3,PAK1,FGFR4,ATP5IF1,HBG2,RHOQ,SLITRK2,MSTN,HOMER2,PPFIA4,MAFB,SLITRK5,STEAP1,HERPUD1,BAIAP2,MAPKAPK2,KCNK15,GRIK4,ADGRB3,CSF1,HK2,PTPRN2,SEMA3A,TESC,MME,SFN,DMXL2,PRKN,ID1,DOCK1,RBFOX2,NTRK3,SLC7A2,TNKS1BP1,PCLO,PPP1R9A,CBLN1,CTNNA2,CYP26A1,SCIN,UNC13B,SLC22A17,PDZD8,ERO1B,BCL6,ADGRL1,ACVR2A,STEAP3,PROS1,SCN2A,MET,FER,EVL,CSN2,NOP53,SLC39A8,PTPN6,ACO1,FGF12,CHRNA6,VIM,GSTO1,AMIGO1,CD40,DOCK5,JAM3,C4BPB,SMAD3,PTPRJ,ITGA2,PTPRS,MAOA,SEPT5,TENM1,DYRK3,SLC6A9,LPAR2,BMPR2,LRP4,TNFSF13B,CLSTN2,GABRG2,IGF2BP2,HBE1,SLX1B,SFXN3,BMP6,ARHGAP44,MCU,NKX6-1,RAB11FIP5,MAP1A,SCN1B,PRKCD,EHD3,STC2,DSG2,KCNMB3,ACTA2,SGK1,SH3PXD2B,PCK2,IQGAP3,TNFRSF11A,SYK,ATP2B1,PCSK6,USP2,RAB3B,MSX1,KDM5B,NUGGC,SYBU,GRID1,FERMT2,ZFPM2,TLR6,LRAT,LEPR,ILDR2,MAP1B,DKK1,SUGT1,DDAH1,ICA1,MYADM,RND3,FBN1,PRCP,SLC16A10,CACNA2D1,ABCG1,SNPH |
| 1.087e-06 | -13.73 | GNF2_DNM1 | MSigDB lists | GNF2_DNM1 | 73 | 22 | 17377 | 1707 |
TYRO3,SV2B,RAB6B,KIF5C,PSD3,NRN1,SLC1A3,SNAP25,RGS7,CAMK2N1,CHN1,MAP1A,SLC22A17,SH3GL2,EHD3,NAP1L3,NPTXR,STXBP1,ZNF365,CTNND2,PNMA2,PGBD5 |
| 1.111e-06 | -13.71 | biliary_tract-gallbladder-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-adenocarcinoma | 2885 | 353 | 17385 | 1698 |
FAM171B,MYCBP2,PPP4R4,PAGE1,LGR4,GRIK2,AASS,ATP8A1,GATA3,FAM102B,NPM1,CEBPA,KIAA1217,SLC9A7,HECTD2,TRPS1,BAG3,DNAH6,SERINC2,THSD1,TSHR,DCC,KLHL23,LRRK2,ELMOD1,ABCC2,KCND3,AHRR,ENPP1,NCKAP1L,ATP7B,B3GALT2,ERCC5,DSEL,SPRY4,NRP1,SEMA6B,CELSR1,SCN8A,LRRC49,APBA1,FOXG1,ADSSL1,MTUS1,SYCP2,RALGPS2,FRY,CNTN4,KIAA1671,PDZD7,MYC,ZIC5,PRKG1,OPN3,GRIP1,MPDZ,NCAM1,AGL,PRR16,COL9A2,RPS23,PTCH2,SLC37A1,KCNQ3,TBC1D8B,STAT4,ARID5B,RAPGEF4,DCHS1,KIAA1324L,C1R,ST6GALNAC3,SNAP25,CDC42BPA,TAF4B,MBNL2,DAGLA,GSTO2,ADAMTS3,THBS4,MATN2,IQSEC2,DHCR7,CDH2,TRPC3,DOCK9,PLA2G4A,TFCP2L1,AMOTL1,RASAL2,CCDC110,GPR65,MYO1B,MSR1,PLXNA2,BEGAIN,RGS20,CHUK,COLEC10,LCP2,COL14A1,TMEM53,SPEG,KMO,COL25A1,DACT1,ALDH1L1,NBEA,DAB2IP,JAKMIP3,RNF145,EBPL,PFKFB2,ADM2,SHANK2,ADCY1,SATB2,ATP1B1,TBC1D16,FGFR1,HTR7,IRS2,ARHGAP21,IKZF3,PRKCB,KLF5,PLD5,CTTNBP2,NR3C2,HACE1,MYO1D,FARP1,ROBO2,EDA2R,ATP9A,ESRP1,BACE1,NKAIN2,GPR180,PKN1,TPD52L1,NEO1,AFF2,TBC1D9,C15orf41,MED12L,B4GALT6,PFKFB4,ARHGEF28,SYNPO2,PTPN13,ZDHHC15,GUCY1A2,ZFP62,GALNT3,NSD1,PCDHB7,TERT,OSBPL5,SVIL,DOCK6,DCBLD1,FOXA1,OCLN,PHC1,NBPF4,KIF5A,PTPN21,ITPR2,FAM13A,NOVA1,HMCN1,PPM1E,SIPA1L2,FKBP9,SEC16B,AADAT,CPVL,EOMES,POF1B,JAKMIP2,TMEM132E,PTPRE,MYRIP,FANK1,TLR4,NEB,SLIT2,PDGFRB,ATL1,ABCC4,ANK2,GDPD1,FAM201A,YAP1,CR2,PLEKHA1,SGK2,TCERG1L,CRYBG3,TMEM132B,TCF7L1,NCAM2,TECPR2,CCDC146,TIGD4,PIK3C2B,PPARGC1A,MAGI2,MLLT3,PCSK5,GPT2,GPR63,BVES,SETBP1,SPINK5,SATB1,DOK5,PGAP1,KIAA1958,GALNT1,NUMBL,SLC30A4,IGF1R,ABCA5,ZNF440,RPS11,PDE10A,GAN,LRP6,ADCY6,LIMCH1,BNIP3,FAR2,FBXL2,NIPAL2,VGLL4,LRP3,NOS3,FGFR4,UNC5C,PCDH10,GPSM1,OBSCN,STRADB,PDE8A,SDK1,B4GALNT3,KHDRBS2,STEAP1,AMDHD1,TBC1D2,KCNK15,KIAA0355,FAT1,RAI14,OSBPL6,PANK3,ZSWIM5,IL15,DOCK1,LPCAT2,MORC4,COL18A1,TDRKH,NTRK3,ZNF83,KIF21B,SEZ6L2,DENND3,FAM110B,TNKS1BP1,DOCK2,DDX60L,PCLO,CBLN1,SEMA6A,SP8,CYP26A1,ZSCAN5A,COL22A1,UNC13B,SETDB2,CDC14B,TACC2,EEPD1,ZNF521,ACVR2A,MDH1B,WWC2,CLVS2,SCN2A,MET,GLI1,CTH,DPP10,INTU,FER,ANTXR2,TMEM67,EVL,PTPRU,PTPN6,PRDM13,TCEAL3,CHRNA6,VIM,DOCK5,ARMC4,ZNF93,RANBP2,NRG3,PTK7,GBP1,ABI3,PTPRS,PSPH,CTNND2,TENM1,TNIK,NECAB2,ARHGEF11,KLHL13,LRP4,PRDM8,IGF2BP2,SFXN3,MAP1A,IPCEF1,IQGAP3,KIAA1211,PNMA2,ESRRG,ASAP3,MEI1,PALLD,FNDC3A,MAP1B,RERE,EBF1,GPR37,DPY19L2,ICA1,DOCK7,EDA,FAT4,FBN1,SLC22A15,RPS12,TBC1D4,MAP3K20,NPHP1,CACNA2D1 |
| 1.111e-06 | -13.71 | gallbladder | COSMIC cancer mutations | gallbladder | 2885 | 353 | 17385 | 1698 |
FAM171B,MYCBP2,PPP4R4,PAGE1,LGR4,GRIK2,AASS,ATP8A1,GATA3,FAM102B,NPM1,CEBPA,KIAA1217,SLC9A7,HECTD2,TRPS1,BAG3,DNAH6,SERINC2,THSD1,TSHR,DCC,KLHL23,LRRK2,ELMOD1,ABCC2,KCND3,AHRR,ENPP1,NCKAP1L,ATP7B,B3GALT2,ERCC5,DSEL,SPRY4,NRP1,SEMA6B,CELSR1,SCN8A,LRRC49,APBA1,FOXG1,ADSSL1,MTUS1,SYCP2,RALGPS2,FRY,CNTN4,KIAA1671,PDZD7,MYC,ZIC5,PRKG1,OPN3,GRIP1,MPDZ,NCAM1,AGL,PRR16,COL9A2,RPS23,PTCH2,SLC37A1,KCNQ3,TBC1D8B,STAT4,ARID5B,RAPGEF4,DCHS1,KIAA1324L,C1R,ST6GALNAC3,SNAP25,CDC42BPA,TAF4B,MBNL2,DAGLA,GSTO2,ADAMTS3,THBS4,MATN2,IQSEC2,DHCR7,CDH2,TRPC3,DOCK9,PLA2G4A,TFCP2L1,AMOTL1,RASAL2,CCDC110,GPR65,MYO1B,MSR1,PLXNA2,BEGAIN,RGS20,CHUK,COLEC10,LCP2,COL14A1,TMEM53,SPEG,KMO,COL25A1,DACT1,ALDH1L1,NBEA,DAB2IP,JAKMIP3,RNF145,EBPL,PFKFB2,ADM2,SHANK2,ADCY1,SATB2,ATP1B1,TBC1D16,FGFR1,HTR7,IRS2,ARHGAP21,IKZF3,PRKCB,KLF5,PLD5,CTTNBP2,NR3C2,HACE1,MYO1D,FARP1,ROBO2,EDA2R,ATP9A,ESRP1,BACE1,NKAIN2,GPR180,PKN1,TPD52L1,NEO1,AFF2,TBC1D9,C15orf41,MED12L,B4GALT6,PFKFB4,ARHGEF28,SYNPO2,PTPN13,ZDHHC15,GUCY1A2,ZFP62,GALNT3,NSD1,PCDHB7,TERT,OSBPL5,SVIL,DOCK6,DCBLD1,FOXA1,OCLN,PHC1,NBPF4,KIF5A,PTPN21,ITPR2,FAM13A,NOVA1,HMCN1,PPM1E,SIPA1L2,FKBP9,SEC16B,AADAT,CPVL,EOMES,POF1B,JAKMIP2,TMEM132E,PTPRE,MYRIP,FANK1,TLR4,NEB,SLIT2,PDGFRB,ATL1,ABCC4,ANK2,GDPD1,FAM201A,YAP1,CR2,PLEKHA1,SGK2,TCERG1L,CRYBG3,TMEM132B,TCF7L1,NCAM2,TECPR2,CCDC146,TIGD4,PIK3C2B,PPARGC1A,MAGI2,MLLT3,PCSK5,GPT2,GPR63,BVES,SETBP1,SPINK5,SATB1,DOK5,PGAP1,KIAA1958,GALNT1,NUMBL,SLC30A4,IGF1R,ABCA5,ZNF440,RPS11,PDE10A,GAN,LRP6,ADCY6,LIMCH1,BNIP3,FAR2,FBXL2,NIPAL2,VGLL4,LRP3,NOS3,FGFR4,UNC5C,PCDH10,GPSM1,OBSCN,STRADB,PDE8A,SDK1,B4GALNT3,KHDRBS2,STEAP1,AMDHD1,TBC1D2,KCNK15,KIAA0355,FAT1,RAI14,OSBPL6,PANK3,ZSWIM5,IL15,DOCK1,LPCAT2,MORC4,COL18A1,TDRKH,NTRK3,ZNF83,KIF21B,SEZ6L2,DENND3,FAM110B,TNKS1BP1,DOCK2,DDX60L,PCLO,CBLN1,SEMA6A,SP8,CYP26A1,ZSCAN5A,COL22A1,UNC13B,SETDB2,CDC14B,TACC2,EEPD1,ZNF521,ACVR2A,MDH1B,WWC2,CLVS2,SCN2A,MET,GLI1,CTH,DPP10,INTU,FER,ANTXR2,TMEM67,EVL,PTPRU,PTPN6,PRDM13,TCEAL3,CHRNA6,VIM,DOCK5,ARMC4,ZNF93,RANBP2,NRG3,PTK7,GBP1,ABI3,PTPRS,PSPH,CTNND2,TENM1,TNIK,NECAB2,ARHGEF11,KLHL13,LRP4,PRDM8,IGF2BP2,SFXN3,MAP1A,IPCEF1,IQGAP3,KIAA1211,PNMA2,ESRRG,ASAP3,MEI1,PALLD,FNDC3A,MAP1B,RERE,EBF1,GPR37,DPY19L2,ICA1,DOCK7,EDA,FAT4,FBN1,SLC22A15,RPS12,TBC1D4,MAP3K20,NPHP1,CACNA2D1 |
| 1.130e-06 | -13.69 | endometrioid_carcinoma | COSMIC cancer mutations | endometrioid_carcinoma | 16178 | 1625 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,CTBP2,BCAN,KIAA1217,SNX9,ABHD6,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,GALNT12,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,RAB38,TTC28,METAP1D,FGFR1,IQCK,IQCH,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,MAGEA6,VWA5A,RCAN3,PACSIN1,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,AHRR,SFXN1,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,ISM1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,RBM11,DNER,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 1.168e-06 | -13.66 | V$TAL1ALPHAE47_01 | MSigDB lists | V$TAL1ALPHAE47_01 | 232 | 47 | 17377 | 1707 |
BCL11B,PHACTR3,SCN5A,ACVR1,RHOBTB1,ARHGAP22,CADM2,SEL1L3,IKZF2,RADIL,FOXP2,NUMBL,MAP1A,LRRN1,SCN1B,STC2,TRIM3,MAP7,MARCH3,SLC2A12,HRK,TSPAN13,GFI1,CPE,GFRA1,NDUFA4L2,MARK1,NR6A1,GJB2,WWC1,MBNL2,PLCB1,HOXA1,TSKU,HTR7,SMAD3,MAP2,ITGBL1,INHBE,B3GALT2,NXPH4,SHOX2,CDH2,TC2N,DDIT3,RAB30,MEF2C |
| 1.170e-06 | -13.66 | GO_HEAD_DEVELOPMENT | MSigDB lists | GO_HEAD_DEVELOPMENT | 691 | 107 | 17377 | 1707 |
ID1,FGF13,AKAP5,RBFOX2,OTX1,PLXNA2,NDRG2,ABAT,NRXN1,BCAN,RAC3,AARS,CBLN1,CTNNA2,SKI,BAG3,EOMES,KCNAB1,TACC2,DLX6,LHX6,DAB2IP,MARCKS,SYNGR3,DNAH5,SLIT2,POU3F3,GLI1,NKX2-1,FZD1,SMAD9,FZD4,WLS,LRRK2,NLGN4X,SATB2,EFHC1,ATOH1,PLEKHA1,ASPH,FGFR1,EML1,TSKU,IRS2,ARMC4,NRG3,GNB4,LAMB1,PTPRS,DLX2,OXTR,BMPR1A,NRP1,PPARGC1A,CTTNBP2,CNTN1,TYRO3,BCL11B,PCDH18,GNG12,SCN5A,BMPR2,ROBO2,ZIC2,PHGDH,GDPD5,FOXG1,CHD5,PGAP1,DDIT4,FOXP2,NUMBL,HMGCS1,CNTN4,SLC7A11,GATA2,AFF2,FLRT3,PRKG1,LRP6,DYNC2H1,ATP2B1,RAX,DISC1,UNC5C,MSX1,RAPGEF2,VLDLR,ARID5B,SLITRK5,MAFB,AK4,CLN5,PLCB1,ZIC1,DKK1,RERE,DOCK7,FAT4,GNAO1,PAX9,BMP4,SEMA3A,CDH2,CRISPLD1,ATP2B4,SNPH |
| 1.172e-06 | -13.66 | IVANOVA_HEMATOPOIESIS_STEM_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL | 239 | 48 | 17377 | 1707 |
MYCBP2,INPPL1,TCTN2,KIF5A,PPFIBP2,GATA3,COBLL1,COL18A1,LRRC49,RASD1,FAM117B,SCD,NTRK3,NRXN1,FAM110B,PPP1R9A,DDIT4,SLC35F1,CHN1,LRRN1,PRKG1,TRIM3,TSPAN13,CERS4,EPHB6,WWC2,SEPT3,ETV1,SLIT2,PRKACB,PNRC1,MYO10,NR4A1,VLDLR,EFNA3,CHRNA6,ARHGAP32,PEAK1,TTC28,TRIM9,IFT81,KCNK15,KCNMB4,LAPTM4B,ZBTB20,GEM,NKX2-8,CHMP4C |
| 1.176e-06 | -13.65 | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP | 171 | 38 | 17377 | 1707 |
LATS2,RUNX2,LGALS3,XYLT1,KIF5C,COBLL1,IL18R1,SEMA4F,SOAT2,PIK3AP1,PROS1,CERS4,ARL4D,ERRFI1,PTPRE,SNX10,ATP2B1,EBPL,TMEM65,SLC39A8,DSTN,PTPN13,HIP1,MARS,VIM,PRDM1,DOCK5,SMPDL3B,GALNT3,PTPRJ,IKZF3,MYADM,ERN1,PCGF2,LRRK1,NRP1,SMYD3,ATP2B4 |
| 1.180e-06 | -13.65 | GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_DN | MSigDB lists | GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_DN | 191 | 41 | 17377 | 1707 |
BCL11B,ATP8A1,GABRR2,SATB1,KBTBD11,UBTD2,TGFBR3,REEP1,MAP7,ADCY6,TSPAN13,MARCKS,ST8SIA1,PACSIN1,MYO6,RASGRP1,CKAP4,ZNF629,PAK1,PDK1,MYO10,MPP1,CYTH3,PRICKLE1,CALCRL,TNS1,ATP1B1,MBNL2,SESN1,MMP15,KCNMB4,BACH2,GPRC5B,PMEPA1,RASGRF2,GNB4,RGS10,SLFN5,AMPD1,SLC16A10,RRAGD |
| 1.193e-06 | -13.64 | SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP | MSigDB lists | SCHMIDT_POR_TARGETS_IN_LIMB_BUD_UP | 25 | 12 | 17377 | 1707 |
CYP51A1,IDI1,MVK,HMGCS1,INSIG1,MSMO1,MVD,LDLR,STARD4,SQLE,DHCR7,CYP26A1 |
| 1.197e-06 | -13.64 | SH3_domain | interpro domains | IPR001452 | 212 | 44 | 18492 | 1811 |
ARHGAP26,SORBS1,DOCK1,RUSC2,UBASH3B,EPS8,SORBS3,TJP1,DOCK3,CACNB4,SNX9,DOCK2,CACNB2,MCF2L,ZDHHC6,SRGAP1,CTTN,SH3PXD2B,PACSIN1,NEB,TNK2,VAV3,SKAP2,MPP1,SHANK2,SPATA13,PACSIN3,ARHGAP32,DOCK5,FRK,SKAP1,BAIAP2,ARHGEF26,FGR,SH3GL2,MPP7,SH3RF1,ABI3,SH3BP4,MPP2,MAP3K21,DLG2,FNBP1L,NPHP1 |
| 1.224e-06 | -13.61 | TGACATY_UNKNOWN | MSigDB lists | TGACATY_UNKNOWN | 619 | 98 | 17377 | 1707 |
AMOTL1,SORBS1,CELSR3,AKAP5,DDR1,CYP26A1,FSTL5,NOS1AP,RND2,SPEG,CDR2L,FBXO32,KCNN2,KCNAB1,ABI3BP,TACC2,PPFIBP1,ZNF521,MAP7,FAM133A,NAP1L3,PDE4D,MYT1,GAB2,TBC1D8,SLC3A2,MEIS2,ACVR1C,LRMP,FGF12,MSRB3,PRKAR2B,ATP1B1,FBXO36,SGK2,BCL11A,TRIM9,ITGBL1,MAP2,ALDOA,ERN1,INPP4B,MAPK10,LIFR,MLLT3,MID1,CTNND2,RAB30,LPP,MEF2C,LRFN5,BMPR2,IGFBP6,CHCHD7,ITPRIP,PTPRD,PLAG1,SLK,SCN8A,COL4A5,TJP1,SORBS3,APBA1,FOXG1,TNFRSF19,FOXP2,EFEMP1,BCHE,NOVA2,FLRT3,TSC22D1,ADCY6,KLF9,IQGAP3,RNF148,PRR16,C15orf41,IGSF3,MICAL2,BDNF,UNC5C,ARAP2,MSTN,FOXN3,LITAF,RASA3,SLITRK5,PRDM1,FAM162A,MAP1B,ZIC1,CEBPB,PTPRC,PLOD2,PELI2,SFMBT1,DLG2,GEM |
| 1.264e-06 | -13.58 | GTGCCTT,MIR-506 | MSigDB lists | GTGCCTT,MIR-506 | 684 | 106 | 17377 | 1707 |
TFCP2L1,CGN,ENAH,CEBPA,SLC2A13,KIF21B,ABHD4,SEMA6A,FSTL5,EYA4,HECTD2,SKI,CDC14B,CNKSR3,DACT1,SLC10A7,SERINC2,BCL6,STEAP3,NAP1L3,JAKMIP3,MYRIP,ANTXR2,ABCC4,FZD4,PRDM13,SHANK2,VIM,RAB38,TSKU,BCL11A,GNAI1,SLC7A1,BACH2,KPNA3,SH3RF1,P4HA2,TECPR2,ERN1,PAM,P4HA1,DLX2,NRP1,NR3C2,LZTS1,LPP,BCL11B,GPT2,TMEM63C,TBC1D1,ZCCHC24,ZNF25,PLAG1,DHCR24,EPS8,SCD,CHSY1,OVOL2,ZNF219,FAM81A,FAM174B,PGAP1,SPIRE1,MCU,RNF141,RAB11FIP5,GBGT1,KIAA1958,NAV1,FRAS1,FLRT3,TSC22D1,SGK1,LIMCH1,FMNL2,MOB1B,QSOX1,PPP1R3D,SLITRK2,MYO10,NR4A1,ARID5B,GRID1,SLITRK5,HIP1,RYR2,PALLD,PLCB1,CPEB1,GLCE,MKX,NEGR1,NAP1L5,MAPKAPK2,TRIB3,TMCO3,MYADM,FCHO2,PCGF2,SLCO5A1,SVIL,TMEM117,FBXO27,CDH2,IL9R,ATP2B4 |
| 1.274e-06 | -13.57 | REACTOME_DEVELOPMENTAL_BIOLOGY | MSigDB lists | REACTOME_DEVELOPMENTAL_BIOLOGY | 378 | 67 | 17377 | 1707 |
DOCK1,PLXNA2,ENAH,CACNB4,SEMA6A,RPS6KA2,ITGB3,ACVR2A,SCN2A,MET,SLIT2,COL6A2,EVL,COL4A3,ACVR1C,DCC,CAP2,PRKCQ,ACVR2B,FGFR1,SMAD3,LAMB1,ITGA2,KLF5,UNC5B,NRP1,PPARGC1A,MEF2C,CNTN1,COL9A3,SCN5A,ROBO2,ARHGEF11,SCN8A,COL4A5,PFN2,NEO1,NKX6-1,ABLIM1,SCN1B,CACNB2,SRGAP1,SREBF1,MED7,NCAM1,GFRA1,COL9A2,CEBPD,FES,PCSK6,PAK1,DPYSL5,UNC5C,KCNQ3,MYO10,HNF4G,COL4A4,SMARCD3,CEBPB,EBF1,PTPRC,SH3GL2,AKT3,MAP2K6,SEMA3A,TRPC3,CDH2 |
| 1.284e-06 | -13.57 | VERHAAK_GLIOBLASTOMA_PRONEURAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_PRONEURAL | 165 | 37 | 17377 | 1707 |
DNM3,CLGN,ABAT,NRXN1,KIF21B,BCAN,EPHB1,SATB1,FAM110B,PFN2,FHOD3,PPM1E,RALGPS2,PDE10A,RAP2A,REEP1,MPPED2,LRP6,MARCKS,NCAM1,MYT1,SCN3A,HRASLS,DBN1,BCL7A,GPM6A,PODXL2,MYO10,ZNF711,MMP15,MAP2,SLCO5A1,MMP16,PURG,MAST1,CNTN1,ATP1A3 |
| 1.322e-06 | -13.54 | CTTTGA_V$LEF1_Q2 | MSigDB lists | CTTTGA_V$LEF1_Q2 | 1128 | 159 | 17377 | 1707 |
CGN,TRIM2,ASS1,DOCK3,IKZF2,HMCN1,FKBP11,PCDH7,RTN1,FBXO32,ABI3BP,ANKFN1,CHRDL1,MPPED2,PPP2R2B,ETV1,TBC1D8,GPM6A,MEIS2,NFE2L1,BNIP3L,SLC25A28,FGF17,TCERG1L,TSKU,TRIM9,ENPP1,ENTPD7,BMP1,ZBTB20,SPRY4,PPARGC1A,NEUROG2,RRAGD,HS6ST3,MEF2C,CHCHD7,GABRB2,JDP2,DHCR24,TNFRSF19,SATB1,IL18R1,MECOM,RALGPS2,PRELID1,TSPAN12,SLC16A9,NIPAL2,FAR2,FIGN,PRR16,VGLL4,GFRA1,CKAP4,PTCH2,GPR176,ENAM,TBC1D8B,DCHS1,HOMER2,EDEM3,TTYH2,HIP1,PRDM1,SNAP25,KHDRBS2,STEAP1,PMEPA1,MPP2,TMEM117,LAPTM4B,SEMA3A,NKX2-8,OSBPL6,MME,CREB3L2,CXCR5,PLA2G4A,SORBS1,ELOVL4,RASAL2,OTX1,MORC4,COL18A1,RNF24,NRXN1,SP8,ZFYVE9,ZNF827,KCTD15,EEPD1,BCL6,ZNF521,NBEA,SHF,DAB2IP,ZNF488,SCN3A,GAB2,GAPDH,RNF145,SOX21,SLC39A8,PRDM13,KCNH5,PANK1,ATOH1,ASPH,IKZF3,PRKCB,PAM,MAPK10,HOXB9,LIFR,MID1,RAB30,HEY1,PCDH18,SLC6A9,DYRK3,BMPR2,BACE1,PLAG1,TNFSF13B,CLSTN2,GABRG2,OVOL2,CREB5,NEO1,NKX6-1,FOXP2,CHN2,PCBP4,SGK3,TSPAN13,IQGAP3,PCK2,C15orf41,MED12L,PFKFB4,MSX1,USP2,FOXN3,ESRRG,CYTH3,ZIC1,DKK1,RERE,NSD1,ICA1,MAP2K6,MCC,DLG2,TNFRSF17,FILIP1,FOXA1,TLL2,PHC1 |
| 1.360e-06 | -13.51 | biological regulation | biological process | GO:0065007 | 12133 | 1248 | 17256 | 1658 |
ARHGAP26,THOC5,GRIK2,RECK,NPM1,CTBP2,CEBPA,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,ZNF788P,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,INPP5F,DIRAS1,TPM1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,TOX,CADPS2,MOXD1,FIGN,JAM2,ZNF385A,KCNQ3,ARID5B,ZNF605,FHL2,FASN,HIP1,SHISA2,SNAP25,ARRDC4,CLN5,SPATA7,TEX15,RPL28,SELENOM,CLMN,LAPTM4B,HOXD13,CDH2,SHTN1,DOCK9,MTG1,TFCP2L1,ADD2,MAPK4,GRK6,PLPP1,TLR3,MAGEA3,ZNF365,MYT1,KIAA1549,KCNB2,FZD1,MYLK3,GAPDH,NECAB1,PFKFB2,ADM2,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,ENTPD1,SLC39A14,CXCL10,ARHGAP21,WFS1,APELA,LAMB1,LRRC27,RAB30,CGB2,GCAT,CKAP2,BACE1,PLAG1,FZD8,ESRP1,CD276,BIK,UBAC2,PSD3,GAS6,SLC12A6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,MN1,LZTS3,RAB6B,RASA3,ATP11A,NSD1,RPL12,SRD5A3,NEK11,BMP4,ATP2B4,PHC1,TLL2,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,FAM13A,RND2,RPS6KA2,SEC16B,ITGB3,TBC1D32,ENO1,RAPGEF5,ZNF391,DBN1,KCNIP3,MARK1,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,CR2,SESN1,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,ADGRA3,NEUROG2,TC2N,ADGRL2,CACUL1,RRAGD,LONRF1,TYRO3,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,FHOD3,SPIRE1,RNF180,NUMBL,ZBTB38,ZNF440,HS3ST5,LRP6,ADCY6,MED7,VGLL4,DPYSL5,BTNL9,EFNA3,GPSM1,SLITRK5,STRADB,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,KCNK15,GRIK4,PLD1,SEMA3A,ID1,DOCK1,RHPN2,NTRK3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF362,IDI1,BCL6,SNAI2,IGFBP3,RPS13,INTU,CSN2,LRRC8B,TMEM65,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,PAK5,KLHL13,MCTP2,RASD1,PRDM8,USP30,FOXP2,KCNMB3,GTF2F2,TSC22D1,TFAP2A,SGK1,TSPAN13,SYK,ATP2B1,CES3,PCSK6,DUSP1,FOXN3,CRIP2,PRICKLE1,FERMT2,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,CD37,DDAH1,DOCK7,FBN1,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,TRPS1,TYMP,ZFYVE28,KCNS3,SERINC2,GLDC,ACVR1C,SLC9C1,KLHL3,WISP3,BNIP3L,EFHC1,GNAI1,SH3RF1,ENPP6,BMP1,MAPK13,SERPINI1,SPRY4,NRP1,SPOCK3,KLF8,MRC2,TBC1D1,MLF1,DHCR24,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,SLC7A11,RALGPS2,NOVA2,MYC,C1QL4,SREBF1,PRKG1,GRIP1,MAST4,PRR16,FAM155A,GPR161,BOD1,PTCH2,RPL26,DISC1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,MMP15,PLEKHH2,PELI2,THBS4,WDR19,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SMYD3,NBL1,TCTN2,RHOD,MSR1,PLXNA2,TMEM170B,DDR1,TIAM2,ZFYVE9,SPEG,ASNS,ZNF438,POU5F1B,SHF,PDE4D,GAB2,SHANK2,PREX1,NLGN4X,ATF3,SATB2,CBY1,ATP1B1,PYGO1,ATOH1,ATP10D,ISG20,SNCA,PATJ,ZNF711,IKZF3,POPDC3,BEX3,CCNA1,ZNF704,HPGD,BMPR1A,MID1,STON2,PURG,COBL,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,NDFIP2,TPD52L1,INPP1,PHLDA2,ADGRB2,GSAP,RASSF8,LRRC55,IRX5,GPR155,AFF2,DYNC2H1,TBC1D9,ERRFI1,SMAD6,SLC40A1,VAV3,SH3BP2,PXN,ARHGEF28,GSTM2,PTPN13,RPL21,HOXA1,ZFP62,TERT,MCC,SVIL,LRRK1,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,F3,GSDME,ADPRHL1,EPCAM,SIPA1L2,PPM1E,ABI3BP,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,CEMIP2,JPH1,YAP1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,OXTR,PPARGC1A,TNFSF4,MAGI2,FRMD5,PCSK5,GPR63,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,SPINK5,RNF141,EEF2,SLC30A4,ZNF354A,INAVA,CAND2,CEBPD,ZNF629,HBG2,ATP5IF1,RHOQ,SLITRK2,STEAP1,HERPUD1,RIPOR2,PLAGL1,NCR3LG1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,FNBP1L,NKX2-8,DMXL2,SORBS1,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,REEP1,FABP6,ACVR2A,FHIT,PROS1,SP140L,ALG10B,PRAME,ANTXR2,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,ZNF569,BCL11A,BATF3,CAMK2N1,ARMC4,ZNF93,TRIM34,EIF4EBP1,RBPMS2,RGS10,DUSP19,MAST1,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,SSX1,SLX1B,IGF2BP2,COL4A5,OVOL2,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,AFAP1L2,IPCEF1,TESPA1,PNMA2,CARD6,USP2,KDM5B,CRIM1,HNF4G,SYBU,ASAP3,TLR6,LRAT,LEPR,CTIF,SUGT1,ICA1,EDA,RND3,ACER2,CTSV,UACA,RPS12,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,LSM11,DNAJC3,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,BAG3,TGFBR3,PPP1R26,FBXO32,PMAIP1,PPFIA2,RAB26,TSHR,ZBED9,NKX2-1,MEIS2,SMAD9,TGFA,CAP2,WLS,ELMOD1,F12,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,LATS2,GNG12,CYP2J2,SLK,GRPEL2,SYCP2,BNIP1,BACE2,CACNB2,ZIC5,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,ZNF518B,FMNL2,GFRA1,CHRM3,LRP12,RPS23,HMGCR,FADS1,BDNF,ENAM,PNP,MYO10,STAT4,CALCRL,SMARCD3,RYR2,PLS1,C1R,TAF4B,OR11H4,MBNL2,CPEB1,BEX4,SH3GL2,ADAMTS3,INHBE,CDH17,SPRED3,TRPC3,BTC,DNM3,ZNF516,TMSB15A,C4A,RGS20,PKP2,IL13RA1,LCP2,NRXN1,COLEC10,CDS1,TXNRD3,GPR15,EPB41L3,CHRNA5,KMO,CNKSR3,DACT1,RTKN2,RAB27B,SYNGR3,FAM155B,PERP,DOCK8,SCN3A,SSH3,FZD4,NKX3-2,KCNH5,ATF7IP2,PXYLP1,RAB38,TTC28,FGFR1,IRS2,GYPC,ZNF697,PEMT,GPR160,WWTR1,PLEKHG1,INPP4B,PAM,TNFSF15,DBP,KLHL31,HOXB9,SERINC5,FARP1,ROBO2,EDA2R,C1QTNF3,IPO5,NKAIN2,P2RY1,CREB5,PKN1,KCNC4,TSPAN17,NEO1,BHLHA15,MCF2L,MYO6,FES,ULBP1,BCL7A,CLYBL,RAPGEF2,MCF2L2,GAREM1,RACK1,HEG1,PTPRC,GALNT3,TRIB3,ID3,PLPPR2,GNAO1,AKT3,XBP1,HK1,JHY,SHOX2,DOCK6,BTRC,FOXA1,TPT1,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,SYT14,NOVA1,KCNAB1,TCAF2,EOMES,KCNN2,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,PLPP2,PLEKHA1,TCERG1L,BATF,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,UBASH3B,RASL11B,SETBP1,MLC1,IL18R1,EFEMP1,KIAA1958,SEMA4F,IGF1R,ABCA5,GATA2,BCHE,PDE10A,BNIP3,FBXL2,PAK1,FGFR4,MID2,UNC5C,HOMER2,TCEA3,SPATA13,PPFIA4,PDE8A,MAPKAPK2,CSF1,HEYL,TESC,SIX2,SFN,MME,PRKN,AVPI1,CFH,AKAP5,RBFOX2,ZNF83,OR51B4,SLC7A2,LPIN3,PCLO,CBLN1,CTNNA2,CYP26A1,TBC1D19,RIDA,SLC22A17,LHX6,ADGRL1,SCN2A,ZNF488,GLI1,CTH,EVL,TMEM67,TUBA1A,NOP53,FGF12,GSTO1,RARRES2,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,KCNG1,ABI3,ITGA2,SEPT5,ZNF701,CNTN1,LPAR2,IL32,GRB14,APBB1,NLRP14,SELL,GABRG2,HBE1,SFXN3,ARHGAP44,PPP2R3A,MAP1A,RASD2,EIF1,PRICKLE2,SH3PXD2B,KLF9,PCK2,SLC45A3,MOB1B,MICAL2,PPP1R3D,NUGGC,LITAF,NUAK2,NPDC1,MAP10,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,DLG2,ZNF808,MYRF,RPL4,PAX9,THAP10,TBC1D4,CGN,MYCBP2,ACVR1,PPP4R4,LANCL3,DUSP8,ATP8A1,GATA3,RAC3,DACH2,AARS,NCS1,STK24,MOK,SLC16A2,FAM168A,CFHR1,CHRDL1,ATRNL1,SP140,PACSIN1,RCAN3,PLTP,TBC1D8,DCDC1,NR6A1,DNAJC6,DEPTOR,MEF2B,SLC25A28,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,GPR150,AHRR,SFXN1,HLF,NCKAP1L,CCBE1,PLK2,RASGRF2,SEMA3C,UNC5B,SPART,ZBED8,LZTS1,EFNB2,INPPL1,ALOX5AP,CELSR1,ZHX3,PTPRD,GABRB2,SCN8A,OPHN1,SLC25A27,GTF2IRD1,TNFRSF10C,SLC1A3,DYNC1I1,CHD5,RPL13A,MYORG,MECOM,MCOLN2,CNTN4,PIK3AP1,PRELID1,OPN3,TSPAN12,RIMS2,IGSF3,RNF152,EPB41L5,QSOX1,TBC1D8B,TCF24,PLCB1,ZNF558,FAM162A,DAGLA,PMEPA1,PKN3,IQSEC2,ACSM3,PLA2G4A,EPHA3,AMOTL1,PCSK1N,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,TBC1D30,NELL2,ZNF827,STARD4,DAB2IP,MARCKS,SERPINH1,PDK1,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,ATG5,MAPK10,NR3C2,KCTD1,RPS20,WASF3,MXI1,ATP9A,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,KDM7A,RGS17,SOAT2,SGK3,RALGAPA2,PRKG2,FIG4,YBX3,GFI1,SPRY2,PFKFB4,SYNPO2,ARAP2,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,ZNF714,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,PCGF2,TUFT1,GRIN2D,B4GALT7,OCLN,ATP1A3,EXPH5,MVK,HEBP1,TNFAIP8L2,JCHAIN,ABAT,CACNB4,RBM11,DNER,ABHD4,IKZF2,KREMEN1,ARHGEF10L,TUBB4A,CYP51A1,GRHL1,AKAP7,DLX6,HRK,EPHB6,PCOLCE2,OR2W3,PTPRE,FANK1,SLIT2,RASGRP1,PRKACB,GPM6A,CAPN5,ZNF565,ROR1,SERGEF,GRK3,C8orf88,NCOA7,APBA2,SLC9B1,BCL11B,UST,FN1,JDP2,ATP6V1E2,CD7,SATB1,PHGDH,ADGRG6,DDIT4,CA2,RPS11,EBF4,NCEH1,BARX1,NOS3,RAX,IL17RD,GPR176,MSTN,SH2D2A,EDEM3,WWC1,DUSP9,PRDM1,ADGRB3,HK2,EGFL7,CREB3L2,CXCR5,NEK10,ZSWIM5,IL15,CELSR3,TDRKH,BCL6B,DOCK2,SP8,ZSCAN5A,SETDB2,UNC13B,RPS6KL1,ZNF521,STEAP3,GULP1,MET,POU2F2,WWC2,ZNF460,HSPA2,DPP10,PHLDB2,FER,SLC39A8,TES,SYNJ2BP,DOCK5,WARS,MSC,BACH2,SOHLH2,DISP1,LIFR,OR51B5,TNIK,REL,LRP4,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,EHD3,DSG2,KIAA0319,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,GRID1,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,RERE,MAP1B,GPR37,TIFA,MYADM,GCSAM,MPP7,NACC2,MAP2K6,PRCP,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 1.367e-06 | -13.50 | GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | MSigDB lists | GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 677 | 105 | 17377 | 1707 |
EPHA3,CGN,BTC,ACVR1,SORBS1,ID1,DOCK1,RBFOX2,STAT5B,NTRK3,LCP2,DDR1,ZFYVE9,SKI,TGFBR3,ITGB3,CHRDL1,ACVR2A,DAB2IP,EPHB6,MET,PTPRE,PDGFRB,GAB2,TNK2,FER,GCNT2,SMAD9,PTPRU,ACVR1C,FGF12,VIM,ACVR2B,FGF17,ROR1,PLEKHA1,FRK,FGFR1,SMAD3,IRS2,INHBC,NRG3,PTPRJ,NCKAP1L,EIF4EBP1,BMP1,HPGD,MAPK13,GRB10,HGF,BMPR1A,NRP1,MAGI2,LIFR,EFNB2,RUNX2,BMPR2,PTPRD,ESRP1,LRP4,EPS8,ATP6V1E2,GAS6,EPHB1,CD7,BMP6,DOK5,DDIT4,EFEMP1,CHN1,IGF1R,FLRT3,GHR,SREBF1,GTF2F2,SMAD6,GFRA1,SYK,FES,FGFR4,PAK1,VEGFC,BDNF,VAV3,MSX1,RHOQ,PXN,MSTN,CRIM1,SH2D2A,RAPGEF2,ARID5B,EFNA3,RYR2,FERMT2,PLCB1,BAIAP2,GPLD1,MAPKAPK2,GALNT3,FGR,CSF1,XBP1,INHBE,BMP4 |
| 1.367e-06 | -13.50 | SH3-like_dom_sf | interpro domains | IPR036028 | 213 | 44 | 18492 | 1811 |
ARHGAP26,SORBS1,DOCK1,RUSC2,UBASH3B,EPS8,SORBS3,TJP1,DOCK3,CACNB4,SNX9,DOCK2,CACNB2,MCF2L,SRGAP1,CTTN,SH3PXD2B,PACSIN1,NEB,TNK2,VAV3,SKAP2,MPP1,SHANK2,SPATA13,PACSIN3,OBSCN,ARHGAP32,DOCK5,FRK,SKAP1,BAIAP2,ARHGEF26,FGR,SH3GL2,MPP7,SH3RF1,ABI3,SH3BP4,MPP2,MAP3K21,DLG2,FNBP1L,NPHP1 |
| 1.388e-06 | -13.49 | GO_CELL_PROJECTION_PART | MSigDB lists | GO_CELL_PROJECTION_PART | 900 | 132 | 17377 | 1707 |
FGF13,PRSS12,GRIK2,KIF5A,NDRG2,RAC3,TUBB4A,KCNN2,KCNAB1,DNAH6,ITGB3,GSTM3,CTTN,PACSIN1,PRKACB,DBN1,GPM6A,ATF4,KCNIP3,WLS,CAP2,DNAJC6,LRRK2,EFHC1,PRKAR2B,PLEKHA1,AK1,TMOD2,SPRY4,NRP1,TPM1,LZTS1,BVES,SCN8A,OPHN1,SLC1A3,BBS9,PFN2,TTC30B,FLRT3,ADCY6,BNIP3,STXBP1,CHRM3,GPR161,EPB41L5,PAK1,DISC1,KCNQ3,MYO10,SPATA6,HOMER2,SPATA13,WWC1,SNAP25,CPEB1,BAIAP2,SPATA7,DAGLA,WDR19,DYNC2LI1,PTPRN2,TESC,MME,DNM3,TCTN2,AKAP5,ADD2,CANX,NRXN1,PPP1R9A,TBC1D30,TIAM2,CTNNA2,CCDC120,EPB41L3,GPRIN1,UNC13B,DAB2IP,MARCKS,SCN2A,DNAH5,GLI1,TMEM67,SHANK2,PREX1,GABARAPL1,SNCA,ARMC4,IFT81,PTPRJ,PEMT,ITGA2,SEPT5,ATG5,CTTNBP2,COBL,MYO1D,FARP1,BMPR2,ROBO2,GLIPR1L1,EPS8,APBB1,CLSTN2,KIF5C,GABRG2,P2RY1,EPHB1,KCNC4,GDPD5,ARHGAP44,SCN1B,EHD3,DYNC2H1,MYO6,SPRY2,ATP2B1,B9D1,DLGAP1,FERMT2,ARHGAP32,PALLD,MAP1B,DOCK7,FGR,TMEM237,DLG2,HK1,KIF1B,ATP2B4,ATP1A3 |
| 1.389e-06 | -13.49 | AATGTGA,MIR-23A,MIR-23B | MSigDB lists | AATGTGA,MIR-23A,MIR-23B | 394 | 69 | 17377 | 1707 |
PPP4R4,DNM3,LGR4,CHUK,ADAMTS6,STAT5B,NRXN1,DOCK3,CHST10,TGFBR3,MPPED2,MARCKS,MET,ETV1,INTU,TNK2,MEIS2,NR6A1,TGFA,DNAJC6,SHANK2,BNIP3L,SATB2,BCL11A,SMAD3,SLC7A1,GPRC5B,RBPMS2,B3GALT2,KLF5,PPARGC1A,MEF2C,LPP,BCL11B,RUNX2,ZNF395,ROBO2,IPO5,COL4A5,NDFIP2,SATB1,MTUS1,CA2,MSMO1,SGK1,TOX,TBC1D9,RRAS2,SEPT3,SPRY2,CHSY3,HNF4G,NUAK2,PHACTR2,CCNG1,PRDM1,PALLD,HOXA1,ZIC1,GLCE,NAP1L5,PLAGL1,NACC2,FBN1,CLDN12,RAI14,DLG2,FNBP1L,PKIA |
| 1.399e-06 | -13.48 | regulation of GTPase activity | biological process | GO:0043087 | 481 | 79 | 17256 | 1658 |
ARHGAP26,EPHA3,RASAL2,DOCK1,GPR65,ARHGAP22,RGS20,PLXNA2,NTRK3,FAM13A,SNX9,TBC1D30,DOCK2,TIAM2,TBC1D19,ADPRHL1,SIPA1L2,BCL6,DAB2IP,SLIT2,DOCK8,RASGRP1,TBC1D8,TNK2,LRRK2,ELMOD1,PREX1,WNT11,CD40,TBC1D16,RANBP2,ARHGAP21,NCKAP1L,ADRB1,RGS10,ARHGAP28,NRP1,RGS16,STXBP5L,BVES,ARHGEF11,TBC1D1,ITGA6,IPO5,OPHN1,ARL2,RGS7,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,SRGAP1,PRKG1,RALGAPA2,ERRFI1,TBC1D9,IQGAP3,SPRY2,RIN2,VAV3,ARAP2,TBC1D8B,RAPGEF2,ASAP3,GPSM1,RASA3,AGAP2,ARHGAP32,RACK1,PLCB1,TBC1D2,DOCK7,ADGRB3,GNAO1,SH3BP4,PTPRN2,TBC1D4,DOCK9 |
| 1.472e-06 | -13.43 | GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP | MSigDB lists | GSE14699_NAIVE_VS_DELETIONAL_TOLERANCE_CD8_TCELL_UP | 140 | 33 | 17377 | 1707 |
EML5,SIDT1,TCP11L2,CNTNAP3,ST6GAL1,BACE1,ELOVL7,TDRKH,ADAMTS6,ITPR2,KBTBD11,TECPR1,TGFBR3,FBXO32,FAM168A,MYC,LRP6,TOX,RASGRP1,CARD6,CD55,KDM5B,PDK1,CRIM1,RAPGEF4,PLEKHA1,SESN1,TRIM34,CCNA1,INPP4B,KIF1B,AMPD1,DIRC2 |
| 1.482e-06 | -13.42 | CERVERA_SDHB_TARGETS_1_UP | MSigDB lists | CERVERA_SDHB_TARGETS_1_UP | 109 | 28 | 17377 | 1707 |
TUBA1A,WLS,UBASH3B,RIMKLA,FHL2,FEZ1,TNFRSF19,KBTBD11,SMPDL3B,MAP1B,LMLN,HPSE,PMAIP1,PLXDC2,REEP1,MAGEA3,SLCO5A1,PGM2L1,FAM149A,PACSIN1,MAGEA6,TANC2,SUSD4,JAM2,SHOX2,SPOCK3,CAND2,PCSK5 |
| 1.482e-06 | -13.42 | axon part | cellular component | GO:0033267 | 347 | 61 | 18223 | 1724 |
MYO1D,FGF13,ROBO2,GRIK2,PRSS12,SCN8A,APBB1,EPS8,BLVRB,OPHN1,KIF5C,NDRG2,KIF21B,KCNC4,GDPD5,PFN2,RAC3,PPP1R9A,TIAM2,CCDC120,TUBB4A,EPB41L3,NAV1,GPRIN1,KCNAB1,UNC13B,MAP1A,SCN1B,FLRT3,ADGRL1,CTTN,SCN2A,NPTXR,PACSIN1,CHRM3,DBN1,GPM6A,KCNIP3,KCNQ3,SHANK2,SYBU,LRRK2,PREX1,FEZ1,SNAP25,ROR1,PALLD,CD40,SNCA,DAGLA,DOCK7,MAP2,ITGA2,RGS10,PTPRN2,TMOD2,DLG2,NRP1,KIF1B,COBL,SHTN1 |
| 1.493e-06 | -13.42 | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | MSigDB lists | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | 456 | 77 | 17377 | 1707 |
EPHA3,PLBD2,ELOVL4,TTC39B,SCAMP1,RECK,PKP2,KCTD12,STAT5B,NTRK3,NHP2,CA8,CACNB4,EPB41L3,SPEG,FKBP9,TLR3,RPS6KA2,ASNS,TACC2,SLC16A2,COL19A1,WWC2,GCA,TMEM43,TGFA,SESN1,DSP,TCF7L1,CXCL10,PTPRJ,ALDOA,WWTR1,PPARGC1A,MAPK10,HEY1,MAST1,MEF2C,BCL11B,LATS2,RUNX2,PTPRD,EPS8,GTF2IRD1,SCD,TJP1,PHGDH,CD7,PFN2,GAS1,HOPX,EFEMP1,MCOLN2,DSG2,SGK1,SLC6A15,PAK1,SLC40A1,CRIM1,STAT4,HOMER2,HIP1,TEX9,CPEB1,EBF1,GALNT3,ID3,DOCK7,ICA1,MYADM,PLAGL1,PMEPA1,SH3BGRL2,LRRK1,GEM,KIF1B,TESC |
| 1.498e-06 | -13.41 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | 410 | 71 | 17377 | 1707 |
EXPH5,MPZL3,CGN,SIDT1,ST14,GALNT6,PPFIBP2,GATA3,CEBPA,ABAT,DDR1,TNKS1BP1,TBC1D30,CDS1,TRPS1,EPCAM,GRHL1,MARVELD2,SERINC2,MAP7,RAB27B,SSH3,TNK2,PTPN6,SHANK2,PREX1,CAMK2N1,GPR160,WFS1,DBP,TTC39A,TC2N,CTNND2,CHMP4C,MYO1D,ESRP1,BIK,BLVRB,OVOL2,TPD52L1,FAM174B,PRRG4,SYCP2,CHN2,MCF2L,TRIM3,ADCY6,TSPAN13,CADPS2,MYO6,PCK2,ZNF385A,EPB41L5,TRPM4,VAV3,PPP1R3D,SLC37A1,CRIP2,ARRDC4,NPDC1,C4orf19,MGMT,SMPDL3B,TRIB3,ICA1,GSTO2,MPP7,XBP1,TUFT1,FOXA1,ABCG1 |
| 1.505e-06 | -13.41 | V$HMGIY_Q6 | MSigDB lists | V$HMGIY_Q6 | 234 | 47 | 17377 | 1707 |
MOCOS,AMOTL1,MRC2,RASAL2,SCAMP1,GPR65,NDRG2,NTRK3,MAPK4,IKZF2,PRRG4,PPP2R3A,HECTD2,KCTD15,CNTN4,KCNAB1,TACC2,EIF1,BCL6,TSC22D1,ST8SIA1,PDE4D,NCAM1,VGLL4,NDUFA4L2,RIN2,PCDH10,MSX1,USP2,OBSCN,PRICKLE1,CALCRL,PEX5L,CD40,BATF,ZIC1,BCL11A,SLC7A1,CXCL10,IKZF3,TERT,MAP2K6,PLXDC2,C1orf21,NXPH4,KLF5,TNFSF4 |
| 1.547e-06 | -13.38 | CHANDRAN_METASTASIS_DN | MSigDB lists | CHANDRAN_METASTASIS_DN | 284 | 54 | 17377 | 1707 |
EPHA3,MAN2B2,PCDH18,NBL1,SORBS1,ROBO2,FGF13,TSPAN15,MCTP2,PSD3,NDFIP2,EYA4,FHOD3,PCDH7,RNF180,SLC22A17,SLC30A4,SMTN,PRICKLE2,PCOLCE2,EPHB6,RAB27B,MOXD1,SLIT2,CHRM3,DUSP1,MN1,PAK1,EPB41L5,ANTXR2,SYNPO2,NR4A1,THSD4,FOXN3,ASAP3,NFIA,ATF3,TNS1,LHPP,JAM3,SMPDL3B,SMAD3,CACHD1,GSTO2,PMEPA1,THBS4,AHNAK2,MCC,PTPRN2,SEMA3C,CAB39L,BMP4,SPOCK3,CACNA2D1 |
| 1.559e-06 | -13.37 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | 80 | 23 | 17377 | 1707 |
EPHA3,FGFR4,TYRO3,ACVR1,BMPR2,ACVR1C,CRIM1,EFNA3,NTRK3,ACVR2B,ROR1,EPHB1,DDR1,FGFR1,EFEMP1,TGFBR3,IGF1R,ACVR2A,BMPR1A,EPHB6,MET,NRP1,PDGFRB |
| 1.560e-06 | -13.37 | synaptic membrane | cellular component | GO:0097060 | 317 | 57 | 18223 | 1724 |
DNM3,CACNG3,GRIK2,GABRB2,LRP4,APBB1,CLSTN2,GABRG2,PSD3,KCTD12,GABRR2,P2RY1,NRXN1,PRR7,CBLN1,NCS1,KCNJ4,SEMA4F,UNC13B,CHRNA5,FLRT3,ADGRL1,LIN7A,GRIP1,CADPS2,MPDZ,STXBP1,CPE,RIMS2,ATP2B1,CHRM3,DLGAP1,DISC1,LZTS3,ANK2,SHANK2,HOMER2,GRID1,NLGN4X,CHRNA6,HIP1,SNAP25,ARHGAP32,CPEB1,BAIAP2,HOMER3,DAGLA,CAMK2N1,GRIK4,FCHO2,MPP2,PTPRS,GRIN2D,DLG2,CDH2,LZTS1,SNPH |
| 1.565e-06 | -13.37 | DLG1 (discs large MAGUK scaffold protein 1) | protein interactions | 1739 | 95 | 26 | 17029 | 1718 |
DLGAP1,PRKN,SCN5A,GRIK2,AKAP5,FZD4,TGFA,BEGAIN,WWC1,PRDM1,APBA1,GUCY1A2,KCNJ4,MAP1A,GPRC5B,KCNAB1,MPP2,ADRB1,LIN7A,DLG2,ADGRA3,MYO6,PTPRE,KIF1B,BTRC,ATP2B4 |
| 1.589e-06 | -13.35 | negative regulation of response to stimulus | biological process | GO:0048585 | 1621 | 211 | 17256 | 1658 |
THOC5,MVK,ACVR1,DUSP8,LGR4,DNAJC3,TNFAIP8L2,LILRB1,GATA3,NDRG2,CHAC1,ABAT,KREMEN1,EYA4,SKI,TGFBR3,ZFYVE28,CHRDL1,CTTN,EPHB6,PTPRE,TLR4,ENO1,SLIT2,PRKACB,PDGFRB,NKX2-1,CD55,SESN2,ATF4,LRRK2,DEPTOR,YAP1,ROR1,F12,PLEKHA1,SESN1,TSKU,PYCR1,ENPP1,INSIG1,SH3RF1,PLK2,NCOA7,TNFRSF1A,SEMA3C,INPP5F,SPRY4,DLX2,NRP1,TNFSF4,UNC5B,PPARGC1A,SPART,MAGI2,MLLT3,PRKAA2,TYRO3,RGS16,LATS2,RUNX2,LGALS3,ITGA6,UBASH3B,RASL11B,SPINK5,MECOM,DDIT4,IGF1R,SEMA4F,GATA2,MYC,FLRT3,C1QL4,PRELID1,PRKG1,LRP6,BARX1,GPR161,ZNF385A,NOS3,RNF152,HMGCR,PTCH2,FGFR4,MSTN,DUSP9,WWC1,STRADB,CALCRL,PDE8A,SHISA2,PRDM1,HERPUD1,RIPOR2,SH3GL2,PMEPA1,HEYL,SH3BP4,EGFL7,CDH2,SEMA3A,EPHA3,PRKN,NBL1,BTC,RASAL2,RGS20,NTRK3,TMEM170B,NRXN1,PIBF1,DDR1,CBLN1,CTNNA2,CYP26A1,TLR3,CNKSR3,DACT1,MAGEA3,BCL6,DAB2IP,PROS1,WWC2,MET,SNAI2,GLI1,CTH,IGFBP3,FZD1,FER,PHLDB2,PRAME,NOP53,PTPN6,PREX1,RNF125,NLGN4X,ATF3,PRKCQ,WNT11,CBY1,GSTO1,SYNJ2BP,FGFR1,C4BPB,SNCA,CAMK2N1,SMAD3,PTPRJ,PRKCB,GBP1,RBPMS2,WFS1,WWTR1,MAP3K21,RGS10,DUSP19,PTPRS,HGF,GRB10,HEY1,DYRK3,ROBO2,IGFBP6,C1QTNF3,GRB14,PAK5,LRP4,NLRP14,UBAC2,NOTUM,GAS6,CUEDC2,EPHB1,RGS7,GDPD5,NEDD4,ARHGAP44,RGS17,PRKCD,SGK3,YBX3,ERRFI1,SMAD6,SPRY2,DUSP1,GSTM2,LITAF,PRICKLE1,RASA3,RACK1,TLR6,SMPDL3B,DKK1,GPR37,PTPRC,TRIB3,DDAH1,MYADM,TERT,FBN1,AKT3,XBP1,PCGF2,MCC,BMP4,DDIT3,ATP2B4,BTRC,TPT1 |
| 1.594e-06 | -13.35 | FAM19A4 (family with sequence similarity 19 member A4, C-C motif chemokine like) | protein interactions | 151647 | 52 | 18 | 17029 | 1718 |
TMEM67,MRC2,COL6A2,TCTN2,FN1,PTPRU,PLXNA2,ITPR2,SEZ6L2,CLN5,LEPR,GPLD1,TGFBR3,PRCP,MOXD1,NRP1,LIFR,B4GALT6 |
| 1.641e-06 | -13.32 | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | MSigDB lists | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | 128 | 31 | 17377 | 1707 |
TNK2,SH3BP2,DYRK3,ACVR1,GCNT2,LGALS3,BMPR2,RAPGEF2,GJB2,LDLR,ARID5B,DHCR24,PPFIBP2,CBS,COL18A1,GSTO1,CCDC85A,CA8,CYP51A1,TRIB3,BAG3,HMGCS1,MSMO1,SERINC2,SVIL,HPGD,ERRFI1,DHCR7,ZFP36L2,IGFBP3,STOM |
| 1.663e-06 | -13.31 | WGTTNNNNNAAA_UNKNOWN | MSigDB lists | WGTTNNNNNAAA_UNKNOWN | 504 | 83 | 17377 | 1707 |
MPZL3,FGF13,PRSS12,OTX1,ADAMTS6,NOVA1,HMCN1,SP8,CYP26A1,PCDH7,COL22A1,ZNF827,ZNF362,ZNF521,NDUFB8,MPPED2,BCL6,PPP2R2B,ETV1,DNAH5,PRKACB,MEIS2,MARK1,SKAP2,PRDM13,FGF12,NFIA,ROR1,ATOH1,TMEM47,FGFR1,INHBC,GYPC,ENTPD7,MAOA,KLF5,ZBTB20,FRMD5,LPP,LRFN5,PCDH18,MXI1,IGFBP6,KLHL13,CREB5,EPHB1,GDPD5,TNFRSF19,COL27A1,PPP2R3A,MECOM,FOXP2,ABLIM1,CHN2,IGF1R,GATA2,SGK3,TFAP2A,TSPAN12,NCAM1,COL9A2,NDUFA4L2,RIN2,BDNF,RHOQ,ESRRG,FOXN3,EDEM3,PRDM1,FNDC3A,MAP1B,CEBPB,NAP1L5,NSD1,KIAA0355,MAP2K6,PLXDC2,SLC7A5,DLG2,BMP4,NKX2-8,SHOX2,FOXA1 |
| 1.667e-06 | -13.30 | C2_domain_sf | interpro domains | IPR035892 | 154 | 35 | 18492 | 1811 |
PLA2G4A,DOC2A,RASAL2,DOCK1,SYT12,MCTP2,HECW2,PRKCA,SYT14,DOCK3,DOCK2,PCLO,NEDD4,SYDE2,RAB11FIP5,CPNE2,UNC13B,PRKCD,DAB2IP,WWC2,RIMS2,DOCK8,CAPN5,RASA3,WWC1,PRKCQ,PLCB1,DOCK5,DOCK7,PRKCB,INPP4B,PIK3C2B,TC2N,DOCK6,DOCK9 |
| 1.668e-06 | -13.30 | ROZANOV_MMP14_TARGETS_UP | MSigDB lists | ROZANOV_MMP14_TARGETS_UP | 256 | 50 | 17377 | 1707 |
MOCOS,PAGE1,IL32,ENO2,FN1,RBFOX2,ST6GAL1,BACE1,COL18A1,HBE1,CHSY1,DDIT4,QPRT,EFEMP1,PMAIP1,ALDOC,SERPINH1,NCAM1,ERRFI1,SNX10,CPE,RIN2,MSX1,COL6A2,FOXN3,GJB2,DSTN,DEPTOR,ATF7IP2,TTYH2,FEZ1,LHPP,SNAP25,ARRDC4,HERPUD1,ISG20,HEG1,IQCK,ENPP1,TDO2,PLOD2,PLK2,RBPMS2,MATN2,EMILIN2,LAMB1,UACA,TPM1,SUSD4,KIF1B |
| 1.674e-06 | -13.30 | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | MSigDB lists | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | 396 | 69 | 17377 | 1707 |
CREB3L2,AVPI1,UGDH,XYLT1,MYO1B,IL13RA1,PRKCA,FKBP11,PLS3,BAG3,GULP1,CTTN,PDGFRB,IGFBP3,FZD1,COL6A2,SKAP2,TMEM43,WLS,ATOX1,FEZ1,GSTO1,ATP10D,DCBLD2,GABARAPL1,SMAD3,SLC39A14,GSN,ITGBL1,TNFRSF1A,BMP1,PAM,RCN3,P4HA1,SEMA3C,ATG5,NRP1,LPP,MAN2B2,GNG12,ANO10,MRC2,IGFBP6,FN1,SEC24D,BACE1,GAS6,SFXN3,EFEMP1,RAB11FIP5,GALNT1,SMTN,FKBP14,SNX7,DUSP1,VEGFC,GPR176,BDNF,QSOX1,PTPN13,FHL2,RABAC1,NPDC1,STEAP1,ID3,FBN1,RAI14,RAB31,PTGES |
| 1.677e-06 | -13.30 | IGARASHI_ATF4_TARGETS_DN | MSigDB lists | IGARASHI_ATF4_TARGETS_DN | 86 | 24 | 17377 | 1707 |
CREB3L2,SLC3A2,ATF4,SEC24D,RHOBTB1,ANK2,CBS,PHGDH,ASPH,LEPR,CDS1,SFXN1,ASNS,AKT3,SLC22A18,DSG2,STC2,SLC7A5,KCNS3,OPN3,POF1B,PGM2L1,PCK2,DENND5B |
| 1.702e-06 | -13.28 | AAGCCAT,MIR-135A,MIR-135B | MSigDB lists | AAGCCAT,MIR-135A,MIR-135B | 314 | 58 | 17377 | 1707 |
EPHA3,BCL11B,LONRF1,RASAL2,BMPR2,RNF144A,JDP2,BACE1,GATA3,KCTD12,IGF2BP2,CREB5,CHSY1,HERC6,NDFIP2,GRPEL2,MTUS1,SKI,SLC35F1,ZNF362,LRRN1,ZDHHC6,RAP2A,NBEA,TRPC1,JAKMIP2,ALPK1,VGLL4,RIMS2,ZNF385A,RNF152,MOB1B,PHLDB2,COL4A3,FOXN3,CACNA1E,VLDLR,ARID5B,ATF3,ATP1B1,C3orf70,FRK,PLCB1,NEGR1,BCL11A,KPNA3,FCHO2,ENTPD7,PELI2,AKT3,DLG2,BMPR1A,CTTNBP2,NR3C2,LZTS1,KCTD1,ATP2B4,MEF2C |
| 1.705e-06 | -13.28 | V$SRY_02 | MSigDB lists | V$SRY_02 | 235 | 47 | 17377 | 1707 |
MXI1,MRC2,FN1,RHOBTB1,KLHL13,RBFOX2,ZIC2,APBA1,TNFRSF19,SATB1,IKZF2,SP8,CCNJ,CHN1,FOXP2,ZNF362,KCNN2,LRRN1,GATA2,ACVR2A,PPP2R2B,RAPGEF5,SEMA6C,PAK1,MID2,NR4A1,CACNA1E,ESRRG,DCHS1,NFE2L1,NFIA,CTTNBP2NL,MBNL2,MAGI3,MAP1B,SMAD3,ZNF711,SLC7A1,EBF1,PELI2,GNAO1,B3GALT2,DLG2,NRP1,NR3C2,MLLT3,HEY1 |
| 1.710e-06 | -13.28 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 783 | 117 | 17385 | 1698 |
CXCR5,EXPH5,CGN,NEK10,CFH,DOCK1,ZNF311,UGDH,GATA3,LILRB1,NPM1,ITPR2,DENND3,PPP1R9A,PCLO,SLCO3A1,CEP85L,PCDH7,TRPS1,FKBP9,ABI3BP,COL25A1,ALDH1L1,MYO3B,ZNF521,BCL6,COL19A1,FAM133A,CTTN,RCAN3,PTPRE,MYRIP,SEMA6C,DPP10,EML6,SMAD9,DCC,WLS,KLHL4,ANK2,MEF2B,FEZ1,SATB2,ATF3,DOCK5,WFS1,TNFRSF1A,NCOA7,DSEL,SUSD4,LRRC27,STON2,CTNND2,HACE1,MAST1,OR51B5,KCNV1,ROBO2,CELSR1,PTPRD,ITGA6,EPS8,MCTP2,CLSTN2,LAMC3,SLC1A3,PRRG4,FHOD3,MCU,SYCP2,FRY,ADCK1,AFF2,MYC,TSC22D1,PRKG1,SGK1,MPDZ,ST8SIA1,NCEH1,FAM155A,TNFRSF11A,LRP12,RIMS2,CHRM3,MED12L,B4GALT6,FGFR4,FADS1,LCA5,ARAP2,PNP,CACNA1E,DCHS1,RYR2,TTC30A,DUSP9,HIP1,SHISA2,CDC42BPA,SDK1,PRDM1,B4GALNT3,PLCB1,GPR137C,RERE,EBF1,RPL12,FAT4,PELI2,ZNF214,XBP1,SVIL,MYOM2,KIF21A,TBC1D4,TLL2 |
| 1.737e-06 | -13.26 | GTPase activator activity | molecular function | GO:0005096 | 287 | 54 | 17224 | 1680 |
ARHGAP26,RGS16,STXBP5L,RASAL2,TBC1D1,ARHGEF11,DOCK1,ARHGAP22,OPHN1,RGS20,FAM13A,RGS7,TBC1D30,DOCK2,TIAM2,ARHGAP44,SYDE2,TBC1D19,CHN1,ADPRHL1,SIPA1L2,RGS17,CHN2,SRGAP1,RALGAPA2,DAB2IP,TBC1D9,ERRFI1,RASGRP1,TBC1D8,VAV3,RIN2,ARAP2,TBC1D8B,RAPGEF2,LRRK2,ELMOD1,ASAP3,PREX1,RASA3,AGAP2,WNT11,ARHGAP32,PLCB1,TBC1D16,TBC1D2,RANBP2,ARHGAP21,ADGRB3,NCKAP1L,RGS10,ARHGAP28,NRP1,TBC1D4 |
| 1.758e-06 | -13.25 | RICKMAN_HEAD_AND_NECK_CANCER_A | MSigDB lists | RICKMAN_HEAD_AND_NECK_CANCER_A | 92 | 25 | 17377 | 1707 |
IL17RD,PRAME,COL9A3,SYNPO2,STXBP6,NLGN4X,ADD2,SHISA2,ZIC2,CENPV,ZNF711,RNF150,COL22A1,FRAS1,FABP6,ZNF704,HPGD,HOXD13,DLX2,PCOLCE2,MOXD1,VASH2,LIFR,COL9A2,KIAA1211 |
| 1.778e-06 | -13.24 | GGGAGGRR_V$MAZ_Q6 | MSigDB lists | GGGAGGRR_V$MAZ_Q6 | 2136 | 272 | 17377 | 1707 |
ACVR1,TCP11L2,LANCL3,DUSP8,PRSS12,VAMP8,LDLR,GATA3,CADM2,NCS1,PCDH7,TRPS1,SLC16A2,RAP2A,CHRDL1,SERINC2,KCNS3,BEND4,SP140,PPP2R2B,TSHR,POU3F3,NKX2-1,MEIS2,KLHL3,NR6A1,KLHL4,BNIP3L,PRKAR2B,TNS1,FGF17,ZDHHC14,ALDOA,MAP9,BMP1,SERPINI1,INPP5F,SPRY4,NRP1,LPP,LRFN5,SCN5A,MRC2,SCN8A,OPHN1,HPCAL4,MTUS1,MECOM,CNTN4,PDZD7,PIK3AP1,NOVA2,CACNB2,MYC,NCAM1,FIGN,PRR16,ZNF385A,BDNF,VLDLR,DCHS1,PACSIN3,SMARCD3,RYR2,PEX5L,SNAP25,ARRDC4,DAGLA,MMP15,PKN3,ADAMTS3,C1orf21,INHBE,CDH2,AMOTL1,ELOVL4,C4A,BEGAIN,OTX1,GRK6,SPEG,COL25A1,DAB2IP,MARCKS,PJA1,FAM155B,MYT1,KCNB2,GARS,GAPDH,KCNH5,SOX21,SHANK2,PANK1,RAB38,FGFR1,SNCA,ENTPD1,GYPC,PDLIM3,P4HA1,TNFSF15,DBP,MAPK10,HOXB9,PURG,MXI1,ANKRD13B,CCDC148,IGFBP6,PLAG1,BACE1,UBAC2,ARL2,PKN1,RGS7,COL27A1,NEO1,ATXN7L1,LRRN1,BHLHA15,PCBP4,ERRFI1,FES,RAB6B,AGPAT4,ZDHHC15,HOXA1,ID3,RPL12,PLXDC2,GNAO1,GRIN2D,BMP4,DOCK6,FOXA1,DDIT3,OCLN,ATP1A3,PHC1,TPT1,PHACTR3,FGF13,NDRG2,ASS1,IKZF2,FSTL5,PLS3,QPRT,TUBB4A,PPM1E,KCNAB1,EOMES,TMEM86A,CNNM2,HRK,JAKMIP2,EPHB6,TMEM132E,ETV1,FANK1,ATL1,SESN2,PNRC1,JPH1,GDPD1,ROR1,RNF44,SESN1,PLEKHB1,TCF7L1,GSN,KLF12,NCAM2,TNFRSF1A,HS6ST3,UST,BCL11B,SV2B,ZNF395,SEC24D,CHCHD7,STXBP6,SCD,ZIC2,SORBS3,PHGDH,SATB1,NUMBL,PRTFDC1,IGF1R,SAMD11,LRP6,VGLL4,RAX,HOMER2,TCEA3,DUSP9,WWC1,SLITRK5,HERPUD1,RAB31,NXPH4,FNBP1L,PANK3,SIX2,CXCR5,SORBS1,ID1,RBFOX2,COL18A1,NTRK3,SEZ6L2,TNKS1BP1,PRR7,SP8,CYP26A1,ZNF362,SLC22A17,TACC2,RPS6KL1,LHX6,ZNF521,MYO3B,GLI1,PRDM13,VIM,FBXO36,BCL11A,PTPRJ,BACH2,PTK7,ABI3,SEPT5,CTNND2,SLC6A9,BMPR2,APBB1,BLVRB,GABRG2,PRDM8,COL4A5,OVOL2,SFXN3,ARHGAP44,KCNJ4,EIF1,STC2,TRIM3,MICAL2,MSX1,USP2,HNF4G,ESRRG,NUAK2,FERMT2,AGAP2,CCNG1,ZFPM2,NPDC1,ILDR2,RERE,DKK1,EBF1,MYADM,FBN1,PRCP,MAP2K6,DLG2,GEM,KIF1B,SNPH |
| 1.799e-06 | -13.23 | striated_muscle | COSMIC cancer mutations | striated_muscle | 4319 | 502 | 17385 | 1698 |
ARHGAP26,DOC2A,MYCBP2,CGN,TCP11L2,SIDT1,GRIK2,PRSS12,DNAJC3,LDLR,NPM1,CTBP2,CEBPA,AARS,RAC3,SKI,TRPS1,EPDR1,BAG3,TGFBR3,DNAH6,PPFIA2,RAB26,KCNS3,GSTM3,ATRNL1,BEND4,PPP2R2B,RCAN3,TSHR,TBC1D8,EML6,ACVR1C,DCC,KLHL23,KLHL4,LRRK2,NFIA,EFHC1,ABCC2,ZDHHC14,GPR150,ENPP1,PLK2,RASGRF2,ADRB1,MAPK13,ERCC5,DSEL,TANC2,DNHD1,SPOCK3,LZTS1,SCN5A,TMEM63C,LATS2,INPPL1,FAM124A,ALOX5AP,CELSR1,ZHX3,TBC1D1,GABRB2,CYP2J2,ITGA6,ZNF25,TJP1,SLC1A3,WDFY4,MTUS1,NAV1,KIAA1671,PDZD7,FAM189A1,FLRT3,ZIC5,VWDE,OPN3,MPDZ,CADPS2,LMAN2,TSPAN12,ALPK1,LOXL4,MOXD1,ZNF518B,AGL,GLIS1,FMNL2,RIMS2,HMGCR,IGSF3,SLC37A1,PNP,KCNQ3,MYO10,COL4A4,ARID5B,DCHS1,FASN,KIAA1324L,RYR2,TTC30A,TTYH2,HIP1,SMARCD3,C1R,PEX5L,CCDC85A,CDC42BPA,CLN5,TMEM74,DAGLA,TEX15,VPS37D,GSTO2,PMEPA1,ADAMTS3,THBS4,CECR2,LRRIQ3,EMILIN2,CDH17,SLFN5,CDH2,AMPD1,DOCK9,PLA2G4A,TBKBP1,AMOTL1,ZNF516,ELOVL4,RNF144A,GALNT12,FAM131C,ZNF311,MYO1B,LRRCC1,MSR1,RGS20,OTX1,ADD2,PKP2,CHUK,KCTD12,COLEC10,TBC1D30,TIAM2,NELL2,SPEG,ZNF827,TLR3,CHRNA5,GPRIN1,KMO,POU5F1B,ALDH1L1,SCRN1,NBEA,RTKN2,DNAH5,MYT1,DOCK8,SCN3A,FZD1,GAB2,GARS,COL6A2,GAPDH,NKX3-2,KCNH5,NLGN4X,SATB2,WNT11,PRKCQ,PYGO1,ATOH1,TTC28,DSP,ATP10D,FGFR1,MAGI3,DCBLD2,ENTPD1,PRKCB,WFS1,LAMB1,MAP3K21,PAM,PLEKHG1,KLF5,FAM149A,KLHL31,LRRC27,COBL,PURG,HACE1,CGB2,ANKRD13D,TMEM132C,WDR17,ROBO2,CD276,ESRP1,ARL2,GABRR2,INPP1,BEX2,COL27A1,NEDD4,NEO1,LRRC55,MGAT1,GPR155,RALGAPA2,MORN2,FIG4,MYO6,NPTXR,SMAD6,GFI1,MED12L,PARP9,MN1,BCL7A,VAV3,ARAP2,CACNA1E,MCF2L2,PTPN13,UCHL3,HEG1,CEBPB,ZFP62,PTPRC,NSD1,PLOD2,TERT,XBP1,MYOM2,TNFRSF17,DOCK6,ATP2B4,OCLN,FOXA1,PHC1,MVK,ACSL1,TRIM16,KIF5A,SYT12,FHDC1,LILRB1,SLC2A13,FAM13A,DNER,HMCN1,FKBP11,CCNJ,RTN1,ARHGEF10L,LGI2,CYP51A1,PPM1E,SIPA1L2,TM9SF2,EOMES,CPVL,SEC16B,LRRC6,HPS1,ANKFN1,ITGB3,TMEM143,JAKMIP2,KIAA1614,SLC2A12,TLN2,TLR4,IL1RAP,NEB,PDGFRB,CYP1B1,MARK1,CD55,ABCC4,PNRC1,COL4A3,SPOCD1,ANK2,CAPN5,JPH1,YAP1,CR2,PLEKHA1,CRYBG3,SERGEF,EML1,TSKU,DYRK1B,FHAD1,TMEM132B,GSN,TCF7L1,HPSE,ITGBL1,NCAM2,MAP2,P4HA2,ERN1,TNFRSF1A,NCOA7,PIK3C2B,OXTR,PPARGC1A,APBA2,NEUROG2,MAGI2,TC2N,MOCOS,STXBP5L,LGALS3,FN1,OTOGL,SCART1,LAMC3,SCD,GALNT13,PFN2,CD7,MLC1,SPINK5,FHOD3,NUMBL,KIAA0895,ZBTB38,IGF1R,BCHE,ZNF440,FRAS1,PDE10A,EBF4,GAN,SMTN,LRP6,ADCY6,VGLL4,LRP3,NOS3,ZNF629,FGFR4,DPYSL5,CDH26,IL17RD,HBG2,PCDH10,PODXL2,SLITRK2,MSTN,SH2D2A,PARD3B,EFNA3,TMTC4,SPATA13,EDEM3,SDC3,WWC1,OBSCN,SLITRK5,PDE8A,PRDM1,SDK1,B4GALNT3,HEYL,FAT1,HK2,PTPRN2,PLD1,DISP2,XKR4,MME,CXCR5,DMXL2,EML5,ZSWIM5,ID1,SORBS1,DOCK1,CELSR3,HECW2,MORC4,COL18A1,COBLL1,NTRK3,ZNF83,SLC7A2,CANX,DENND3,RADIL,DDX60L,PCLO,CYP26A1,FAM131B,COL22A1,PDZD8,SLC22A17,UNC13B,TACC2,EEPD1,BCL6,STEAP3,MYH15,WWC2,MET,SCN2A,ZNF460,NTNG1,SEMA6C,SP140L,IGFBP3,DPP10,FER,CSN2,TMEM65,SLC39A8,PTPN6,THSD4,TES,ACO1,RNF125,GSTO1,VIM,AMIGO1,DOCK5,CENPV,C4BPB,ARMC4,PTPRJ,PTK7,TMPRSS9,ITGA2,MAOA,HGF,DISP1,CTNND2,TENM1,COL9A3,DYRK3,BMPR2,KLHL13,ARHGEF11,GRB14,RUSC2,LRP4,NSUN6,COL4A5,NOTUM,CUEDC2,SEL1L3,TECPR1,MAP1A,SCN1B,TFAP2A,KIAA0319,TSC22D1,PRICKLE2,TSPAN13,DHRS12,KIAA0408,IQGAP3,KIAA1211,CES3,USP2,LRRIQ1,CRIM1,NR4A1,ESRRG,SYBU,LITAF,OGDHL,ASAP3,MEI1,PRICKLE1,AGAP2,ZFPM2,NPDC1,LEPR,MGMT,SMPDL3B,RERE,EBF1,ADAMTS17,DOCK7,FAT4,FBN1,NACC2,THSD7B,ZNF474,KIF21A,TBC1D4,PTGES,MMP16 |
| 1.916e-06 | -13.17 | DHR_1 | prosite domains | PS51650 | 11 | 8 | 12060 | 1278 |
DOCK7,DOCK1,DOCK3,DOCK5,DOCK6,DOCK2,DOCK8,DOCK9 |
| 1.916e-06 | -13.17 | DHR_2 | prosite domains | PS51651 | 11 | 8 | 12060 | 1278 |
DOCK7,DOCK1,DOCK3,DOCK5,DOCK6,DOCK2,DOCK8,DOCK9 |
| 1.932e-06 | -13.16 | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_UP | MSigDB lists | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_UP | 181 | 39 | 17377 | 1707 |
ACVR1,ARHGEF11,ITGA6,EPS8,MORC4,SELL,NDRG2,GAS6,FAM13A,DDR1,KBTBD11,PFN2,TPD52L1,BAG3,SLC22A17,DACT1,MCF2L,LRP6,ACVR2A,FHIT,EPHB6,RCAN3,MAST4,IL1RAP,COL4A3,CRIP2,EDEM3,PDE8A,SLC25A28,ACVR2B,NPC2,TAF4B,CLN5,TTC28,RERE,ICA1,TPM1,TBC1D4,SLC16A10 |
| 1.976e-06 | -13.13 | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | MSigDB lists | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | 81 | 23 | 17377 | 1707 |
VAV3,CELSR1,GRB14,SLC27A2,SHANK2,PRKAR2B,ABAT,FAM174B,SLC19A2,ASNS,PLK2,WFS1,STC2,XBP1,OPN3,CADPS2,MYO6,MAST4,TTC39A,RAPGEF5,CEBPD,PERP,TBC1D8 |
| 2.056e-06 | -13.09 | skin-face-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-face-carcinoma-squamous_cell_carcinoma | 2079 | 264 | 17385 | 1698 |
MYCBP2,CTBP2,BCAN,DACH2,NOS1AP,TRPS1,TGFBR3,CHRDL1,ATRNL1,PPP2R2B,DCC,ALDH1L2,LRRK2,LRMP,DEPTOR,ABCC2,FGF17,GPC6,SFXN1,ATP7B,RASGRF2,MAP9,INPP5F,DSEL,NRP1,LRFN5,INPPL1,FAM124A,CELSR1,EHHADH,ZHX3,CYP2J2,APBA1,DYNC1I1,MECOM,ABLIM1,RSL24D1,BNIP1,RALGPS2,FRY,CNTN4,PIK3AP1,SRGAP1,GRIP1,ZNF518B,AGL,LRP12,QSOX1,KCNQ3,COL4A4,FASN,ZBBX,PLCB1,C4orf19,ZNF558,TEX15,PLEKHH2,LRRIQ3,EMILIN2,MPP2,CLMN,SFMBT1,SMYD3,EPHA3,ST14,ZNF311,PLXNA2,DDR1,ZNF438,KMO,COL25A1,SCRN1,DNAH5,C3orf67,VNN2,TMEM43,SOX21,KCNH5,ADCY1,WNT11,ATP10D,FGFR1,IQCH,LAMB1,FAM149A,PLD5,CTTNBP2,NR3C2,COBL,MID1,FARP1,WDR17,ANKRD13B,CD276,PRSS35,NKAIN2,CREB5,NEDD4,RGS17,AFF2,GAS2L3,ERRFI1,ULBP1,TMC7,SYNPO2,MCF2L2,RAPGEF2,ELOVL3,AK4,RASA3,GUCY1A2,PTPRC,GALNT3,PCDHB7,TERT,AKT3,SVIL,MYOM2,B4GALT7,TLL2,ATP1A3,EXPH5,ACSL1,MVK,TRIM16,ACTL8,PTPN21,ASS1,C20orf194,ITPR2,SYT14,HMCN1,RTN1,SIPA1L2,RPS6KA2,KCNN2,TMEM86A,ANKFN1,TRPC1,COL19A1,TLN2,TLR4,SLIT2,PDGFRB,ITGB7,GPM6A,SLC3A2,COL4A3,ABCC4,ANK2,CR2,RNF44,SPNS1,KLF12,PIK3C2B,PPARGC1A,MAGI2,STXBP5L,BVES,ELOVL7,SETBP1,GALNT13,ZNF215,FHOD3,PCDHB14,RNF180,ZBTB38,ZNF440,ABCA5,LRP6,LIMCH1,PTPRCAP,SLCO4C1,NOS3,PCDH10,PODXL2,MGAT4B,SLITRK5,PDE8A,PRDM1,NEGR1,MAPKAPK2,GRIK4,PLAGL1,HK2,RAI14,SEMA3A,OSBPL6,NEK10,CFH,XYLT1,RHPN2,HECW2,KIF21B,DENND3,PIBF1,RADIL,DOCK2,PPP1R9A,CYP26A1,COL22A1,SLC22A17,TACC2,REEP1,ZNF521,PROS1,GULP1,MET,TMEM56,GLI1,HRASLS,CTH,DPP10,TMEM67,PTPRU,SLC39A8,FGF12,RARRES2,RANBP2,ZNF93,NRG3,PTPRJ,BACH2,TMPRSS9,HGF,OR51B5,IL32,GRB14,CLGN,ARHGEF11,REL,NLRP14,MCTP2,SSX1,TNFSF13B,IGF2BP2,SLC35F1,MAP1A,SCN1B,KIAA0319,KIAA0408,IPCEF1,PCK2,IQGAP3,TNFRSF11A,KIAA1211,DUSP1,DLGAP1,USP2,LRRIQ1,HNF4G,GRID1,PRICKLE1,PALLD,TGDS,SMPDL3B,RERE,MAP1B,DOCK7,FAT4,ZNF214,KIF21A,FILIP1,CACNA2D1 |
| 2.060e-06 | -13.09 | BROWNE_HCMV_INFECTION_24HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_DN | 142 | 33 | 17377 | 1707 |
LGALS3,RECK,GRIK2,GAS6,PRKCA,RPS6KA2,SLC16A2,PRKG1,ACTA2,FIG4,MET,VWA5A,RRAS2,PDGFRB,IGFBP3,FADS1,B9D1,PDLIM7,GPR176,RIN2,UROS,CRIM1,MGST3,PTPN13,BNIP3L,CCNG1,MGMT,DDAH1,FBN1,ITGA2,SEMA3C,DBP,ATP2B4 |
| 2.079e-06 | -13.08 | anchoring junction | cellular component | GO:0070161 | 550 | 86 | 18223 | 1724 |
ARHGAP26,SORBS1,ARHGAP22,PKP2,NPM1,ENAH,CADM2,TNKS1BP1,CTNNA2,KAZN,PPFIBP1,ITGB3,LIN7A,POF1B,MARCKS,CTTN,TLN2,PERP,PDGFRB,FZD1,RPS13,PHLDB2,TNK2,EVL,TES,CAPN5,VIM,TNS1,TMEM47,DSP,JAM3,GSN,LMLN,GYPC,PTK7,ITGA2,OXTR,SPRY4,NRP1,CTNND2,FRMD5,LPP,EFNB2,MRC2,BMPR2,STXBP6,ITGA6,ARL2,SORBS3,TJP1,RPL13A,FLRT3,RPS11,EHD3,DSG2,SCARF2,TSPAN9,RRAS2,FES,EPB41L5,PDLIM7,PAK1,CDH26,SYNPO2,PXN,PARD3B,CYTH3,ASAP3,FHL2,FERMT2,PALLD,SNTB1,PEAK1,BAIAP2,PTPRC,RPL12,DOCK7,RND3,MPP7,FAT1,SVIL,RPL4,CDH2,NPHP1,CSRP2,MME |
| 2.099e-06 | -13.07 | PEREZ_TP63_TARGETS | MSigDB lists | PEREZ_TP63_TARGETS | 316 | 58 | 17377 | 1707 |
GPT2,ARHGAP26,COL9A3,SERINC5,STOX2,ACSL1,FGF13,ZCCHC24,BIK,ASS1,COL18A1,ANKRD18A,ZIC2,SEZ6L2,ABHD6,PGAP1,COL27A1,EPB41L3,SIPA1L2,IGF1R,FRY,CNKSR3,REEP1,MARCH3,TOX,MOXD1,KLHL29,SMAD6,SLIT2,RASGRP1,ZNF385A,ULBP1,LAMP3,IGFBP3,FZD1,EPB41L5,SMAD9,ACVR1C,SLC39A8,FOXN3,SPATA13,ELMOD1,ADCY1,EFNA3,MAFB,ATP11A,MKX,GPR37,CACHD1,TEX15,PTPRJ,TUFT1,DLX2,OXTR,UNC5B,HS6ST3,HEY1,PCSK5 |
| 2.131e-06 | -13.06 | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | MSigDB lists | KAN_RESPONSE_TO_ARSENIC_TRIOXIDE | 117 | 29 | 17377 | 1707 |
EFNB2,ENO2,TRIM16,GPR65,LDLR,BNIP3L,AK4,CBS,KCTD12,ATF3,SCD,PHGDH,SEL1L3,FAM162A,GABARAPL1,DDIT4,DCBLD2,DKK1,TRIB3,ASNS,SLC7A11,KLF12,INSIG1,PLK2,STC2,GSTM3,DDIT3,CTH,HEY1 |
| 2.139e-06 | -13.06 | DELYS_THYROID_CANCER_UP | MSigDB lists | DELYS_THYROID_CANCER_UP | 437 | 74 | 17377 | 1707 |
RASAL2,FLVCR2,ST14,C4A,GALNT12,VAMP8,MSR1,IL13RA1,CBLN1,PCDH7,NELL2,RPS6KA2,PMAIP1,SLC22A18,PROS1,CTTN,MET,PTPRE,IL1RAP,IGFBP3,CYP1B1,ITGB7,CD55,PTPRU,TGFA,ROR1,DSP,WARS,ENTPD1,GPRC5B,NCKAP1L,TDO2,MAP2,PTK7,P4HA2,ITGA2,TNFRSF1A,AHNAK2,TNFSF15,MAPK13,MBOAT2,MYO1D,MRC2,ALOX5AP,IGFBP6,FN1,LGALS3,PLAG1,LRP4,EPS8,PSD3,IGF2BP2,TNFRSF10C,SEL1L3,PHLDA2,MTUS1,MSMO1,SCN1B,MYO6,IGSF3,QSOX1,KCNQ3,PNP,HIP1,PRDM1,ATP11A,NPC2,EMILIN2,SLC7A5,SLC1A5,CDH2,DHCR7,SFN,DOCK9 |
| 2.150e-06 | -13.05 | RIGGINS_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_DN | 209 | 43 | 17377 | 1707 |
SERINC5,MXI1,CLGN,PLEKHA5,UGDH,KIF5C,PSD3,ABAT,HMGCS1,RPS6KA2,IGF1R,PMAIP1,PDE10A,DSG2,STC2,STEAP3,GULP1,TBC1D9,CEBPD,CYP1B1,VAV3,MSX1,RAPGEF2,ARID5B,SYBU,SATB2,RAB38,PALLD,DSP,PLCB1,PLEKHB1,NT5DC2,MAPKAPK2,RANBP2,PDLIM3,FAT1,RAI14,RAB31,INPP4B,LAPTM4B,SEMA3C,MMP16,CTNND2 |
| 2.150e-06 | -13.05 | KIM_WT1_TARGETS_UP | MSigDB lists | KIM_WT1_TARGETS_UP | 209 | 43 | 17377 | 1707 |
ENO2,BMPR2,GTF2IRD1,DOK5,PHLDA2,PCDH7,F3,CYP51A1,HMGCS1,CA2,MYC,PDE10A,PRKCD,SGK1,KLF9,RRAS2,PTPRE,ZNF365,SPRY2,IL1RAP,ATP2B1,SNAI2,ARAP2,NR4A1,ARID5B,C3orf52,FHL2,LITAF,FERMT2,TNS1,ATP1B1,BAIAP2,SMAD3,SLC7A1,RND3,CSF1,WWTR1,RAI14,GRB10,GEM,CDH2,COBL,SFN |
| 2.158e-06 | -13.05 | YTATTTTNR_V$MEF2_02 | MSigDB lists | YTATTTTNR_V$MEF2_02 | 643 | 100 | 17377 | 1707 |
EPHA3,ARHGAP26,RASAL2,FGF13,GRIK2,DNAJC3,PTPN21,MORC4,RNF24,SEMA6A,PPM1E,ZNF362,DACT1,PPFIA2,BCL6,NBEA,ACVR2A,ETV1,DOCK8,HRASLS,TMEM67,MARK1,NR6A1,PANK1,FGF12,NFIA,PRKAR2B,KCND3,ATOH1,ASPH,BCL11A,ENPP1,KCNMB4,KLF12,ITGBL1,GNB4,P4HA1,HPGD,KLF5,PPARGC1A,LIFR,NR3C2,MLLT3,FRMD5,PRKAA2,MXI1,INPPL1,BMPR2,GCAT,MLF1,GABRR2,CREB5,DYNC1I1,PGAP1,NEDD4,PPP2R3A,CHN1,FOXP2,MAP1A,SLC30A4,FLRT3,ZIC5,FAM107B,HS3ST5,TSC22D1,TFAP2A,MARCH3,RNF148,NCAM1,RIMS2,SNX7,MID2,BDNF,ARAP2,RHOQ,USP2,HNF4G,ESRRG,NR4A1,PACSIN3,STRADB,OBSCN,PRDM1,SNAP25,ZFPM2,PALLD,MBNL2,GPLD1,CEBPB,EBF1,PLAGL1,MPP7,KIAA0355,CLDN12,GNAO1,C1orf21,TMEM117,SLCO5A1,GRIN2D,DLG2 |
| 2.175e-06 | -13.04 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 1302 | 178 | 17377 | 1707 |
THOC5,MVK,ACVR1,DUSP8,LGR4,DNAJC3,TNFAIP8L2,GATA3,LILRB1,NDRG2,ABAT,CHAC1,SKI,TGFBR3,ZFYVE28,CHRDL1,CTTN,TLR4,PTPRE,SLIT2,PRKACB,NKX2-1,CD55,ATF4,LRRK2,DEPTOR,YAP1,FEZ1,PLEKHA1,F12,TSKU,PYCR1,ENPP1,SH3RF1,TNFRSF1A,SEMA3C,INPP5F,DLX2,SPRY4,UNC5B,NRP1,TNFSF4,MAGI2,MLLT3,LZTS1,TYRO3,PRKAA2,LATS2,SEMA6B,RGS16,RUNX2,LGALS3,ITGA6,ST6GAL1,UBASH3B,RASL11B,SPINK5,DDIT4,MECOM,SEMA4F,IGF1R,PIK3AP1,GATA2,FLRT3,MYC,C1QL4,PRELID1,PRKG1,LRP6,BARX1,ZNF385A,GPR161,NOS3,RNF152,HMGCR,PTCH2,QSOX1,MSTN,DUSP9,CALCRL,WWC1,STRADB,PRDM1,HERPUD1,SH3GL2,PMEPA1,HEYL,SH3BP4,EGFL7,CDH2,SEMA3A,NBL1,RASAL2,RGS20,GRK6,NRXN1,PIBF1,SEMA6A,CTNNA2,CYP26A1,TLR3,CNKSR3,DACT1,BCL6,DAB2IP,PROS1,WWC2,MET,SEMA6C,SNAI2,CTH,FZD1,GLI1,IGFBP3,PRAME,PHLDB2,FER,PTPN6,NLGN4X,WNT11,ATF3,CBY1,GSTO1,PRKCQ,SYNJ2BP,C4BPB,SNCA,SMAD3,PTPRJ,PRKCB,GBP1,WFS1,WWTR1,RGS10,DUSP19,HGF,GRB10,SUSD4,HEY1,C1QTNF3,ROBO2,IGFBP6,CD276,LRP4,UBAC2,CUEDC2,NOTUM,OVOL2,GAS6,RGS7,GDPD5,PPP2R3A,NEDD4,RGS17,PRKCD,ERRFI1,SMAD6,SPRY2,DUSP1,GSTM2,LITAF,RASA3,PRICKLE1,SMPDL3B,DKK1,GPR37,PTPRC,MYADM,FBN1,TERT,XBP1,PCGF2,MCC,BMP4,BTRC,ATP2B4,DDIT3,TPT1 |
| 2.183e-06 | -13.03 | GO_REGULATION_OF_CELL_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_CELL_DEVELOPMENT | 799 | 119 | 17377 | 1707 |
EPHA3,NBL1,DNM3,ID1,FGF13,AKAP5,PLXNA2,GATA3,LILRB1,BCL6B,NTRK3,RAC3,SEMA6A,PPP1R9A,STK24,NCS1,SKI,RND2,EOMES,RAP2A,BCL6,DAB2IP,MARCKS,CTTN,PACSIN1,ZNF488,SLIT2,SEMA6C,NKX2-1,DBN1,SSH3,PHLDB2,GCNT2,MYLK3,DCC,LRRK2,PREX1,YAP1,FEZ1,VIM,AMIGO1,ATOH1,SAV1,FGFR1,BCL11A,SMAD3,NRG3,GPRC5B,GBP1,PTK7,PLK2,WWTR1,TNFRSF1A,SEMA3C,INPP5F,HGF,DLX2,BMPR1A,NRP1,MAGI2,COBL,LZTS1,CNTN1,MEF2C,UST,BCL11B,SEMA6B,TNIK,BMPR2,ROBO2,FN1,PTPRD,PLAG1,ST6GAL1,LRP4,APBB1,OVOL2,GDPD5,BMP6,NEDD4,NKX6-1,EFEMP1,CHN1,NUMBL,CNTN4,SEMA4F,SCN1B,GATA2,KIAA0319,SGK1,ADCY6,FIG4,GFI1,SLC45A3,RIMS2,FES,EPB41L5,VEGFC,BDNF,DISC1,RAPGEF2,VLDLR,SMARCD3,SNAP25,SDK1,CPEB1,BAIAP2,MAP1B,DKK1,NEGR1,DOCK7,MYADM,HEYL,CSF1,BMP4,SEMA3A,SHOX2,CDH2,FOXA1 |
| 2.205e-06 | -13.02 | import into cell | biological process | GO:0098657 | 608 | 94 | 17256 | 1658 |
PRKN,DNM3,CACNG3,PRSS12,DOCK1,LDLR,MSR1,LILRB1,JCHAIN,SLC7A2,CANX,SNX9,DNER,RAC3,DOCK2,ZFYVE9,SLC9A7,TXNDC5,ITGB3,STEAP3,GULP1,CTTN,FAM155B,PACSIN1,SNX10,TNK2,SLC3A2,SLC9C1,SLC39A8,ANK2,DNAJC6,LRRK2,NLGN4X,ATP1B1,GRK3,SNCA,SLC7A1,SLC39A14,GSN,ENPP1,WIPF3,NCKAP1L,INPP5F,STON2,TYRO3,MRC2,INPPL1,SCART1,ATP9A,LRP4,OPHN1,SLC36A4,GAS6,SLC1A3,MLC1,NEDD4,GATA2,PRKCD,GHR,LRP6,MARCH3,LOXL4,MYO6,DENND1C,FAM155A,SYK,LRP3,LRP12,SNX7,PAK1,TRPM4,PDLIM7,RIN2,VAV3,RHOQ,MYO10,VLDLR,PACSIN3,HIP1,CALCRL,SNAP25,LEPR,STEAP1,BAIAP2,MAPKAPK2,FGR,SH3GL2,FCHO2,SH3BP4,RAB31,SLC1A5,FNBP1L,CACNA2D1,ATP2B4 |
| 2.225e-06 | -13.02 | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | MSigDB lists | VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_UP | 162 | 36 | 17377 | 1707 |
GXYLT2,FN1,ACTL8,MSR1,SLC1A3,GAS1,EFEMP1,STC2,BCL6,TRPC1,MOXD1,SNX10,CPE,FKBP14,SLIT2,IL1RAP,SNAI2,CYP1B1,IGFBP3,GDAP1,ALDH1L2,MAFB,GPC6,RIMKLB,ITGBL1,FBN1,PLOD2,THBS4,PLXDC2,AKT3,GNB4,ISM1,WWTR1,RAB31,CRISPLD1,HEY1 |
| 2.229e-06 | -13.01 | GSE3982_MAST_CELL_VS_NKCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_UP | 182 | 39 | 17377 | 1707 |
PLA2G4A,MYO1D,ACVR1,ZNF516,SORBS1,NDRG2,SCD,CHAC1,ABHD6,QPRT,FKBP9,RSL24D1,FRY,TSC22D1,MARCH3,WWC2,ESD,STXBP1,HSPA2,LRP12,TBC1D8,FER,PPP1R3D,MEIS2,ABCC4,LRRC8B,TGFA,SLC7A1,RPL12,ADAMTS3,PMEPA1,FAT1,RAI14,RGS10,GRB10,NRP1,TBC1D4,SMYD3,LARP1 |
| 2.237e-06 | -13.01 | GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 324 | 59 | 17377 | 1707 |
UST,EPHA3,SEMA6B,TNIK,DNM3,ID1,FN1,ROBO2,BMPR2,FGF13,PTPRD,AKAP5,ST6GAL1,LRP4,PLXNA2,NTRK3,OVOL2,RAC3,SEMA6A,PPP1R9A,NEDD4,NKX6-1,CHN1,RND2,NUMBL,SEMA4F,RAP2A,SGK1,DAB2IP,MARCKS,CTTN,SLIT2,SEMA6C,NKX2-1,EPB41L5,SSH3,BDNF,DISC1,PHLDB2,GCNT2,DCC,RAPGEF2,LRRK2,PREX1,AMIGO1,BAIAP2,MAP1B,BCL11A,SMAD3,MYADM,GBP1,WWTR1,SEMA3C,NRP1,SEMA3A,SHOX2,CDH2,LZTS1,FOXA1 |
| 2.294e-06 | -12.99 | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 7630 | 835 | 17385 | 1698 |
DOC2A,THOC5,ADAL,FLVCR2,GRIK2,AASS,CNTNAP3,PRSS12,RECK,DNAJC3,LSM11,FAM102B,NPM1,ALG1L,STAT5B,CTBP2,CADM2,CHAC1,BCAN,DOCK3,KIAA1217,EYA4,NOS1AP,BAG3,TGFBR3,PPFIA2,TMED9,PPP2R2B,COG3,TSHR,DCC,KLHL23,CAP2,GJB2,LRRK2,ELMOD1,ABCC2,F12,MFSD6,INTS6,PYCR1,ZNF266,ATP7B,MAP9,ALDOA,BBC3,ERCC5,INPP5F,ZBTB20,DNHD1,TMEFF2,CRYL1,MEF2C,CARS,SCN5A,LATS2,TMEM63C,STOX2,CYP2J2,ITGA6,TJP1,FOXG1,BBS9,HPCAL4,SYCP2,RSL24D1,FRY,PAIP2B,CACNB2,TOX,DENND1C,NCAM1,MOXD1,FMNL2,GFRA1,LRP12,HMGCR,BDNF,SLC37A1,PNP,KCNQ3,MYO10,SPATA6,ARID5B,ZNF605,FASN,FHL2,RYR2,HIP1,AIG1,ZBBX,TAF4B,DHX32,BEX4,CACHD1,TEX15,TMCO3,SH3GL2,EMILIN2,CDH17,CLMN,CDH2,TRPC3,DOCK9,TFCP2L1,DNM3,ZNF516,GALNT12,MYO1B,LRRCC1,ABHD13,PKP2,ADD2,IL13RA1,GRK6,LCP2,NRXN1,SLC19A2,GPR15,RNF150,EPB41L3,TLR3,GPRIN1,COL25A1,CNKSR3,DACT1,MAGEA3,ALDH1L1,RTKN2,DNAH5,MYT1,SCN3A,DOCK8,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,FZD4,KCNH5,TRAM1L1,ADCY1,DSP,ASPH,ZNF618,FGFR1,MAGI3,GJC1,SLC39A14,ENTPD1,ARHGAP21,IQCH,WFS1,GPR160,WWTR1,LAMB1,INPP4B,PAM,PLEKHG1,ALG11,TNFSF15,PLD5,DBP,C2orf88,CCDC148,FARP1,WDR17,CKAP2,ESRP1,BACE1,IPO5,UBAC2,PSD3,CREB5,PKN1,EPHB1,BEX2,COL27A1,NEO1,PCBP4,MYO6,ZFP36L2,MED12L,FES,PARP9,ULBP1,TRPM4,PDLIM7,MN1,RAPGEF2,ELOVL3,RASA3,ATP11A,SNTB1,HEG1,GALNT3,PTPRC,TRIB3,NSD1,PCDHB7,OSBPL5,NEK11,BMP4,HK1,DOCK6,DCBLD1,FOXA1,PHC1,TLL2,PHACTR3,NMNAT3,CACNG3,FGF13,SYT12,FHDC1,ASS1,LILRB1,MGAT5B,ITPR2,SYT14,FSTL5,CCNJ,ANKRD42,RUFY4,CPNE2,FKBP9,EOMES,KCNAB1,SEC16B,KCNN2,TMEM86A,ITGB3,TMEM143,COL19A1,JAKMIP2,KIAA1614,TLN2,ETV1,ENO1,TLR4,NEB,PGBD5,DBN1,SLC3A2,GCNT2,MARK1,ATF4,ABCC4,COL4A3,SPOCD1,ANK2,NFE2L1,PLEKHA1,TCERG1L,CRYBG3,TSKU,SPNS1,TCF7L1,INSIG1,KLF12,MAP2,GNB4,TECPR2,CCDC146,TNFRSF1A,PIK3C2B,MLLT3,LONRF1,PRKAA2,KCNV1,RUNX2,ITPRIP,CHCHD7,SETBP1,ZNF215,IL18R1,PGAP1,DOK5,FHOD3,HSPA12B,RNF180,KIAA1958,ZBTB38,SEMA4F,IGF1R,ABCA5,BCHE,ZNF440,FRAS1,HS3ST5,SMTN,LRP6,ADCY6,SLCO4C1,FAR2,NIPAL2,CKAP4,FGFR4,CHSY3,UNC5C,BTNL9,RNF170,GPSM1,TMTC4,WDR25,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,TEX9,GPR19,BAIAP2,NEGR1,TBC1D2,ATPAF2,CSF1,SIX2,SFN,CFH,AKAP5,DOCK1,RHPN2,RNF24,ZNF83,NTRK3,SLC7A2,FAM198B,KIF21B,LPIN3,SEZ6L2,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,CYP26A1,TBC1D19,FAM131B,SLC22A17,TACC2,MYO3B,BCL6,ZDHHC23,MYH15,CLVS2,SCN2A,INTU,TMEM67,EVL,THSD4,PRDM13,ACO1,CHRNA6,FRK,C4BPB,IFT81,RANBP2,NRG3,PTPRJ,ITGA2,PTPRS,SUSD4,CTNND2,CNTN1,HEY1,MAN2B2,TENM1,PCDH18,DYRK3,SLC6A9,KLHL13,RUSC2,APBB1,MCTP2,RASD1,PPP2R3A,FOXP2,TTC1,TECPR1,MAP1A,RASD2,KCNMB3,TSC22D1,PRICKLE2,KIAA0408,KLF9,PCK2,KIAA1211,ATP2B1,CES3,DLGAP1,PPP1R3D,MICAL2,LRRIQ1,NUAK2,FERMT2,PALLD,MGMT,SMPDL3B,HOMER3,DKK1,DDAH1,DOCK7,FAT4,FBN1,L3MBTL4,ZNF214,DLG2,SLC22A15,SLC1A5,TBC1D4,PTGES,KIF1B,FILIP1,CACNA2D1,ZNF235,FAM171B,MYCBP2,PLBD2,LGR4,SIDT1,TTC39B,TCP11L2,LDLR,PPFIBP2,GATA3,AARS,TRPS1,ZFYVE28,CFHR1,SLC22A18,SLC16A2,SERINC2,NDUFB8,KCNS3,ATRNL1,BEND4,MAGEA6,VWA5A,PLTP,TBC1D8,GLDC,DCDC1,ACVR1C,NR6A1,WISP3,FAM84A,LRMP,TNS1,ACVR2B,SAV1,ZDHHC14,SFXN1,SH3RF1,ENPP6,NCKAP1L,PLK2,CCBE1,BMP1,MAPK13,DSEL,NRP1,TANC2,UNC5B,SEMA6B,LRFN5,MRC2,INPPL1,FAM124A,CELSR1,PTPRD,ZHX3,TBC1D1,SCN8A,GABRB2,SLC25A27,OPHN1,MRPL22,SLC1A3,APBA1,ADSSL1,DYNC1I1,TNFRSF19,MECOM,MTUS1,ABLIM1,RALGPS2,SLC7A11,KIAA1257,PIK3AP1,MYC,RUNDC3B,PRELID1,PRKG1,CPXM2,GRIP1,SLC16A9,MPDZ,GPR161,IGSF3,EPB41L5,PTCH2,TBC1D8B,SLC36A1,PLEKHA8,COL4A4,VLDLR,RAPGEF4,DCHS1,PACSIN3,KIAA1324L,TTC30A,TTYH2,CDC42BPA,FAM162A,DAGLA,VPS37D,PLEKHH2,PMEPA1,PKN3,CECR2,THBS4,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,SLFN5,AMPD1,ACSM3,EPHA3,PLA2G4A,TCTN2,RASAL2,RHOD,GPR65,CCDC110,PLXNA2,CHUK,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,TMEM53,ZNF827,SPEG,ALDOC,SHF,SCRN1,PDE4D,SERPINH1,TRDMT1,VNN2,TMEM43,SHANK2,PANK1,PREX1,SATB2,CBY1,PRKCQ,PYGO1,ATP1B1,ATP10D,DCBLD2,IKZF3,TDO2,BMPR1A,CTTNBP2,STON2,MID1,COBL,HACE1,DENND5B,ANO10,ANKRD13D,MXI1,PLSCR4,CCNJL,HERC5,GABRR2,RGS7,GDPD5,TPD52L1,NEDD4,RASSF8,RGS17,LRRC55,SOAT2,MGAT1,GPR155,SGK3,RALGAPA2,SLC6A15,DYNC2H1,TBC1D9,ERRFI1,SMPDL3A,B4GALT6,TMC7,VAV3,ALDH2,ARHGEF28,ARAP2,PXN,SH3BP2,SYNPO2,CACNA1E,MPP1,PTPN13,ZDHHC15,ZIC1,FGR,OR2T33,MCC,SVIL,GRIN2D,MYOM2,TNFRSF17,SLC43A1,ATP1A3,NUDT17,EXPH5,ACSL1,KIF5A,UGDH,PTPN21,ACTL8,DNER,IKZF2,KREMEN1,SLCO3A1,HMCN1,RTN1,ARHGEF10L,LGI2,ADPRHL1,PPM1E,SIPA1L2,AKAP7,SLC10A7,ANKFN1,TRPC1,SLC2A12,PCOLCE2,PTPRE,OR2W3,RASGRP1,PDGFRB,CYP1B1,TNK2,ATL1,SESN2,SKAP2,JPH1,ROR1,SGK2,RNF44,SERGEF,TMEM132B,GSN,AK1,GPRC5B,ITGBL1,NCOA7,TNFSF4,APBA2,PCSK5,GPT2,UST,BCL11B,SV2B,ZNF395,FN1,RHOBTB1,BVES,LAMC3,ATP6V1E2,GALNT13,FAM81A,PHGDH,SATB1,PCDHB14,RNF141,CA2,EEF2,LIMCH1,RNF148,NCEH1,CAND2,NOS3,CDH26,GPR176,PCDH10,PODXL2,SLITRK2,MSTN,PARD3B,EDEM3,SDC3,WWC1,PRDM1,B4GALNT3,AMDHD1,STEAP1,GLCE,TMEM154,KIAA0355,FAT1,RAI14,TMEM117,EGFL7,FNBP1L,XKR4,DMXL2,EML5,ZSWIM5,NEK10,SORBS1,CELSR3,PSTPIP2,PLEKHA5,HECW2,MORC4,COL18A1,COBLL1,DOCK2,ZSCAN5A,SCIN,COL22A1,PDZD8,SETDB2,UNC13B,CDC14B,RPS6KL1,PPFIBP1,REEP1,ZNF521,MAP7,ACVR2A,STEAP3,PROS1,MET,POU2F2,ZNF460,NTNG1,SEMA6C,PHLDB2,PTPRU,PTPN6,TES,MVD,TCEAL3,SYNJ2BP,CD40,DOCK5,TPK1,BCL11A,ARMC4,ZNF93,LMLN,BACH2,TRIM34,KPNA3,TMPRSS9,CYP2U1,LIFR,PSPH,MAST1,TNIK,ENO2,PRSS16,ARHGEF11,CLGN,TSPAN15,REL,LRP4,NSUN6,SSX1,CLSTN2,COL4A5,OVOL2,FAM174B,SEL1L3,BMP6,SYDE2,FSD1,PRKCD,DSG2,EHD3,TRIM3,AFAP1L2,IPCEF1,IQGAP3,FKBP14,RBMS2,RIN2,CARD6,MSX1,RAB3B,HNF4G,NR4A1,ESRRG,SYBU,OGDHL,GRID1,MEI1,CCNG1,ARHGAP32,ZFPM2,GALNT14,NAALADL2,MAP1B,RERE,ADAMTS17,GPR37,DPY19L2,MFSD9,MYADM,NACC2,RND3,PRCP,MAP2K6,THSD7B,UACA,KIF21A,RNF157,IL9R,NPHP1,SNPH |
| 2.307e-06 | -12.98 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_UP | 189 | 40 | 17377 | 1707 |
EXPH5,TNIK,ENO2,GALNT6,ST6GAL1,APBB1,SLC25A27,TDRKH,COL4A5,SATB1,PFN2,MCU,SLC30A4,RALGPS2,ZFYVE28,FAM168A,BCL6,TSC22D1,ADCY6,SHF,TOX,MARCKS,RASGRP1,RBMS2,CAND2,ATL1,BCL7A,KDM5B,SPATA6,ZDHHC15,PRRG1,BAIAP2,SLC39A14,IFT81,BACH2,PLOD2,PRKCB,MAP2K6,ABI3,PHC1 |
| 2.322e-06 | -12.97 | skin-trunk-malignant_melanoma | COSMIC cancer mutations | skin-trunk-malignant_melanoma | 2701 | 331 | 17385 | 1698 |
PPP4R4,LGR4,GRIK2,PRSS12,ATP8A1,CADM2,CA8,EYA4,STK24,PCDH7,TRPS1,DNAH6,SLC16A2,PPFIA2,PPP2R2B,GLDC,MEIS2,SMAD9,DCC,CAP2,GJB2,TNS1,SFXN1,SH3RF1,ENPP6,PLK2,ATP7B,RASGRF2,MAP9,BMP1,ARHGAP28,ERCC5,SERPINI1,NRP1,UNC5B,SPOCK3,LRFN5,SCN5A,TMEM63C,MRC2,INPPL1,EHHADH,PTPRD,ZHX3,LRRC49,SLC1A3,WDFY4,TNFRSF10C,APBA1,TNFRSF19,TTC30B,GAS1,MECOM,MTUS1,SYCP2,RALGPS2,KIAA1257,CNTN4,ADCK1,PIK3AP1,CACNB2,MYC,ZIC5,C1QL4,SRGAP1,TOX,LOXL4,STXBP1,FMNL2,LRP12,RIMS2,CHRM3,IGSF3,RNF152,PTCH2,QSOX1,SLC36A1,COL4A4,RAPGEF4,ZNF605,RYR2,CALCRL,ARRDC4,PLCB1,C4orf19,TMEM74,SPATA7,CACHD1,TEX15,ADAMTS3,CECR2,CLMN,IQSEC2,AMPD1,DOCK9,PLA2G4A,TFCP2L1,NBL1,DNM3,ZNF516,GALNT6,LRRCC1,MSR1,PKP2,NRXN1,COL14A1,ZFYVE9,ZNF827,CHRNA5,NBEA,RAB27B,DNAH5,GATM,SCN3A,MYLK3,GARS,COL6A2,B3GALT1,TMEM43,PFKFB2,NPM3,KCNH5,PRKCQ,DSP,ASPH,ATP10D,METAP1D,ARHGAP21,CCNA1,INPP4B,FAM149A,CTTNBP2,COBL,STON2,MID1,ANO10,MYO1D,CCDC148,ROBO2,ATP9A,EPS8,EPHB1,NDFIP2,GDPD5,KCNC4,COL27A1,NEDD4,NEO1,AFF2,SLC6A15,ERRFI1,MED12L,ARAP2,LCA5,CACNA1E,UCHL3,SNTB1,SKAP1,PTPRC,GALNT3,TRIB3,OR2T33,PCDHB7,PLOD2,TERT,SRD5A3,TUFT1,SVIL,MYOM2,ATP1A3,EXPH5,LILRB1,SLCO3A1,RTN1,LGI2,RND2,PPM1E,SIPA1L2,RPS6KA2,SEC16B,ABI3BP,MARVELD2,ITGB3,LIN7A,TRPC1,JAKMIP2,KIAA1614,MYRIP,OR2W3,NEB,SLIT2,RASGRP1,ZNF391,ATF4,KCNIP3,SKAP2,ABCC4,ANK2,JPH1,CR2,TTC22,ROR1,SESN1,TMEM132B,ITGBL1,P4HA2,FAM114A2,NCOA7,MAGI2,TC2N,MLLT3,CHMP4C,KCNV1,MOCOS,STXBP5L,CYP4V2,ZNF215,CHSY1,FAM81A,SPINK5,SATB1,PCDHB14,KIAA1958,ZBTB38,KIAA0895,EBF4,LIMCH1,VGLL4,NOS3,FGFR4,PPFIA4,WDR25,OBSCN,PRDM1,TEX9,GPR19,TBC1D2,PLAGL1,FAT1,HK2,XKR4,OSBPL6,CFH,CELSR3,XYLT1,COBLL1,TDRKH,OR51B4,KIF21B,FAM110B,TNKS1BP1,UBTD2,DDX60L,SP8,ZSCAN5A,FAM131B,TBC1D19,UNC13B,TACC2,RPS6KL1,MYO3B,MAP7,MYH15,MET,SP140L,HRASLS,DPP10,PHLDB2,UROS,PTPRU,TES,FGF12,ACO1,DOCK5,ARMC4,SMAD3,MSC,RANBP2,NRG3,PTPRJ,TTC39A,MBOAT2,LIFR,CTNND2,MAST1,OR51B5,PCDH18,BMPR2,PRSS16,ARHGEF11,KLHL13,MCTP2,CLSTN2,PRDM8,COL4A5,USP30,NKX6-1,SCN1B,EIF1,DSG2,KIAA0319,DHRS12,TSPAN13,SH3PXD2B,ATP2B1,DLGAP1,MICAL2,RAB3B,HNF4G,LRRIQ1,GRID1,PRICKLE1,AGAP2,EXOG,ZFPM2,FNDC3A,NAALADL2,ILDR2,MAP1B,MKX,CTIF,DPY19L2,FAT4,L3MBTL4,FMO4,THSD7B,RPL4,GEM,FILIP1,CACNA2D1,SNPH |
| 2.333e-06 | -12.97 | GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | MSigDB lists | GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 295 | 55 | 17377 | 1707 |
EPHA3,SCN5A,ID1,CELSR1,RHOD,GPR65,EPS8,PKP2,ADD2,SORBS3,NTRK3,PFN2,PPP1R9A,SPIRE1,NOS1AP,FHOD3,SCIN,PPM1E,DSG2,PRKCD,CTTN,PDE4D,SLIT2,NEB,FES,PDGFRB,TRPM4,PAK1,SSH3,FER,PHLDB2,RHOQ,MYLK3,EVL,ANK2,DSTN,ASAP3,PREX1,RYR2,WNT11,PRKCQ,DSP,JAM3,BAIAP2,SMAD3,GSN,PLEKHH2,MYADM,NCKAP1L,WIPF3,PAM,TMOD2,TMEFF2,TPM1,MEF2C |
| 2.344e-06 | -12.96 | S_TK_X | smart domains | SM00133 | 49 | 18 | 9493 | 1056 |
LATS2,PRKCQ,GRK6,CDC42BPA,SGK2,PKN1,PRKCA,GRK3,RPS6KA2,PKN3,PRKCB,AKT3,PRKCD,PRKG1,SGK3,SGK1,PRKG2,PRKACB |
| 2.344e-06 | -12.96 | HER-positive_carcinoma | COSMIC cancer mutations | HER-positive_carcinoma | 2055 | 261 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,THOC5,ACVR1,GATA3,STAT5B,PRKCA,STK24,HECTD2,FBXO32,DNAH6,PMAIP1,RAP2A,PPP2R2B,VWA5A,TSHR,NKX2-1,ACVR1C,TGFA,KLHL4,DNAJC6,PRKAR2B,ABCC2,FGF17,ACVR2B,SAV1,SH3RF1,RASGRF2,ADRB1,BBC3,MAPK13,ERCC5,DIRAS1,SPRY4,NRP1,TMEFF2,LPP,MEF2C,CARS,LRFN5,LATS2,INPPL1,CELSR1,PTPRD,ITGA6,MLF1,FOXG1,MECOM,SYCP2,ABLIM1,KIAA1257,CNTN4,MYC,VWDE,RUNDC3B,RIMS2,PTCH2,STAT4,CALCRL,HIP1,CACHD1,SQLE,LAPTM4B,HOXD13,SLFN5,CDH2,TRPC3,EPHA3,PLA2G4A,BTC,RHOD,CHUK,DDR1,TLR3,KMO,DNAH5,DOCK8,FZD1,GAB2,COL6A2,RNF145,PDK1,FZD4,WNT11,PRKCQ,ATF3,FGFR1,MAGI3,IRS2,IKZF3,PRKCB,GRB10,BMPR1A,MID1,HACE1,IGFBP6,CKAP2,FZD8,PLAG1,BIK,UBAC2,KIF5C,HERC5,P2RY1,PKN1,EPHB1,NEDD4,GHR,SGK3,RALGAPA2,SEPT3,SPRY2,MED12L,PARP9,MN1,BCL7A,VAV3,PXN,RAPGEF2,RASA3,UCHL3,GUCY1A2,NSD1,FGR,PLOD2,AKT3,GNAO1,NEK11,GRIN2D,BMP4,TNFRSF17,BTRC,DDIT3,EXPH5,FGF13,DNER,ABHD4,HMCN1,KREMEN1,CEP85L,RPS6KA2,TM9SF2,POF1B,SLC2A12,TLN2,TLR4,ETV1,NEB,PDGFRB,PRKACB,DBN1,CR2,YAP1,PLEKHA1,ROR1,SGK2,RNF44,TCF7L1,GPRC5B,TNFRSF1A,PIK3C2B,MAGI2,TC2N,MLLT3,PRKAA2,BCL11B,SEC24D,JDP2,RASL11B,PGAP1,IL18R1,SPIRE1,OTUD1,NUMBL,PRTFDC1,IGF1R,LRP6,NOS3,FGFR4,PAK1,UNC5C,IL17RD,CDH26,TMTC4,MAFB,DUSP9,PRDM1,STEAP1,GLCE,MAPKAPK2,HK2,EGFL7,PLD1,SEMA3A,SFN,DMXL2,CXCR5,ZSWIM5,CFH,HECW2,NTRK3,CANX,RADIL,CBLN1,BCL6,ACVR2A,MET,GLI1,IGFBP3,PTPRU,PTPN6,FGF12,CD40,ZNF569,BCL11A,WARS,RANBP2,MAGEA12,NRG3,EIF4EBP1,PTK7,SOHLH2,SEPT5,LIFR,HEY1,CNTN1,LPAR2,BMPR2,CLGN,REL,APBB1,TNFSF13B,SSX1,RASD1,USP30,PPP2R3A,RASD2,PRKCD,TSC22D1,SGK1,ACTA2,RRAS2,TNFRSF11A,SYK,RBMS2,DUSP1,PPP1R3D,RIN2,USP2,OGDHL,AGAP2,TLR6,MGMT,DKK1,DPY19L2,GPR37,EBF1,RND3,MAP2K6,GEM |
| 2.344e-06 | -12.96 | breast-carcinoma-HER-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-HER-positive_carcinoma | 2055 | 261 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,THOC5,ACVR1,GATA3,STAT5B,PRKCA,STK24,HECTD2,FBXO32,DNAH6,PMAIP1,RAP2A,PPP2R2B,VWA5A,TSHR,NKX2-1,ACVR1C,TGFA,KLHL4,DNAJC6,PRKAR2B,ABCC2,FGF17,ACVR2B,SAV1,SH3RF1,RASGRF2,ADRB1,BBC3,MAPK13,ERCC5,DIRAS1,SPRY4,NRP1,TMEFF2,LPP,MEF2C,CARS,LRFN5,LATS2,INPPL1,CELSR1,PTPRD,ITGA6,MLF1,FOXG1,MECOM,SYCP2,ABLIM1,KIAA1257,CNTN4,MYC,VWDE,RUNDC3B,RIMS2,PTCH2,STAT4,CALCRL,HIP1,CACHD1,SQLE,LAPTM4B,HOXD13,SLFN5,CDH2,TRPC3,EPHA3,PLA2G4A,BTC,RHOD,CHUK,DDR1,TLR3,KMO,DNAH5,DOCK8,FZD1,GAB2,COL6A2,RNF145,PDK1,FZD4,WNT11,PRKCQ,ATF3,FGFR1,MAGI3,IRS2,IKZF3,PRKCB,GRB10,BMPR1A,MID1,HACE1,IGFBP6,CKAP2,FZD8,PLAG1,BIK,UBAC2,KIF5C,HERC5,P2RY1,PKN1,EPHB1,NEDD4,GHR,SGK3,RALGAPA2,SEPT3,SPRY2,MED12L,PARP9,MN1,BCL7A,VAV3,PXN,RAPGEF2,RASA3,UCHL3,GUCY1A2,NSD1,FGR,PLOD2,AKT3,GNAO1,NEK11,GRIN2D,BMP4,TNFRSF17,BTRC,DDIT3,EXPH5,FGF13,DNER,ABHD4,HMCN1,KREMEN1,CEP85L,RPS6KA2,TM9SF2,POF1B,SLC2A12,TLN2,TLR4,ETV1,NEB,PDGFRB,PRKACB,DBN1,CR2,YAP1,PLEKHA1,ROR1,SGK2,RNF44,TCF7L1,GPRC5B,TNFRSF1A,PIK3C2B,MAGI2,TC2N,MLLT3,PRKAA2,BCL11B,SEC24D,JDP2,RASL11B,PGAP1,IL18R1,SPIRE1,OTUD1,NUMBL,PRTFDC1,IGF1R,LRP6,NOS3,FGFR4,PAK1,UNC5C,IL17RD,CDH26,TMTC4,MAFB,DUSP9,PRDM1,STEAP1,GLCE,MAPKAPK2,HK2,EGFL7,PLD1,SEMA3A,SFN,DMXL2,CXCR5,ZSWIM5,CFH,HECW2,NTRK3,CANX,RADIL,CBLN1,BCL6,ACVR2A,MET,GLI1,IGFBP3,PTPRU,PTPN6,FGF12,CD40,ZNF569,BCL11A,WARS,RANBP2,MAGEA12,NRG3,EIF4EBP1,PTK7,SOHLH2,SEPT5,LIFR,HEY1,CNTN1,LPAR2,BMPR2,CLGN,REL,APBB1,TNFSF13B,SSX1,RASD1,USP30,PPP2R3A,RASD2,PRKCD,TSC22D1,SGK1,ACTA2,RRAS2,TNFRSF11A,SYK,RBMS2,DUSP1,PPP1R3D,RIN2,USP2,OGDHL,AGAP2,TLR6,MGMT,DKK1,DPY19L2,GPR37,EBF1,RND3,MAP2K6,GEM |
| 2.394e-06 | -12.94 | LU_EZH2_TARGETS_DN | MSigDB lists | LU_EZH2_TARGETS_DN | 347 | 62 | 17377 | 1707 |
PLSCR4,ANKRD13D,ACSL1,BMPR2,SEC24D,GRB14,RECK,RBFOX2,OTX1,ENAH,CREB5,BMP6,MOK,IDI1,TECPR1,RPS6KA2,CHRNA5,BACE2,TACC2,DSG2,NBEA,SLC16A9,LIMCH1,FAM84B,SERPINH1,FAR2,KLHL29,PTPRE,FKBP14,ATP2B1,IGSF3,IGFBP3,HMGCR,FZD1,IL17RD,TBC1D8B,SLC36A1,ACO1,TMTC4,LITAF,SATB2,SHISA2,CCNG1,PALLD,ASPH,GLCE,GJC1,DKK1,HEG1,IRS2,DDAH1,CACHD1,TMEM154,KPNA3,CCBE1,LAMB1,HK2,DUSP19,SEMA3C,TNFSF15,ATP2B4,SLC16A10 |
| 2.455e-06 | -12.92 | TGACAGNY_V$MEIS1_01 | MSigDB lists | TGACAGNY_V$MEIS1_01 | 776 | 116 | 17377 | 1707 |
EPHA3,DNM3,ID1,CACNG3,FGF13,RHOD,PLXNA2,BCL6B,RNF24,NRXN1,TNKS1BP1,IKZF2,EYA4,PLS3,TUBB4A,UNC13B,IKZF5,ALDOC,LHX6,REEP1,MPPED2,ACVR2A,BEND4,PPP2R2B,MDH1B,ETV1,MYT1,GATM,SEMA6C,POU3F3,GAB2,GLI1,DPP10,GPM6A,MEIS2,SESN2,SHANK2,JPH1,FGF12,SGK2,SESN1,EML1,MAGI3,WARS,ENTPD1,KLF12,BACH2,MAP2,ENTPD7,P4HA2,GNB4,B3GALT2,BMP1,KLF5,GRB10,PPARGC1A,NEUROG2,NR3C2,INPPL1,RHOBTB1,GCAT,CD276,BACE1,APBB1,CLSTN2,CREB5,APBA1,SEL1L3,TNFRSF19,DYNC1I1,PRRG4,NEDD4,FOXP2,HMGCS1,CHN2,MAP1A,SLC7A11,SLC30A4,PDZD7,MYC,PCBP4,FLRT3,SAMD11,STC2,SGK3,LRP6,NCAM1,ERRFI1,C15orf41,CKAP4,MN1,PPP1R3D,PCDH10,USP2,ESRRG,VLDLR,EDEM3,PRICKLE1,OBSCN,HIP1,WWC1,PRDM1,CDC42BPA,HOXA1,CEBPB,TMEM154,ADAMTS3,PELI2,GNAO1,NXPH4,SHOX2,KIF1B,DDIT3,FILIP1,CRISPLD1,ATP1A3 |
| 2.464e-06 | -12.91 | upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma-nasopharyngeal_carcinoma | 1462 | 195 | 17385 | 1698 |
ARHGAP26,EXPH5,UGT8,ACVR1,TTC39B,PPFIBP2,C20orf194,ANKRD18A,CADM2,MGAT5B,PRKCA,KIAA1217,EYA4,LGI2,SIPA1L2,RPS6KA2,DNAH6,PPFIA2,ANKFN1,CHRDL1,KIAA1614,CTTN,NEB,TBC1D8,PGBD5,LAMP3,ERGIC1,COL4A3,ALDH1L2,ANK2,LRRK2,NFIA,TMEM200C,CR2,EFHC1,ROR1,FGF17,ENPP1,GPRC5B,ENPP6,MAP2,P4HA2,ALDOA,TNFRSF1A,PIK3C2B,DSEL,UNC5B,TMEFF2,MAGI2,KCNV1,FN1,TBC1D1,STXBP6,LAMC3,TJP1,CHSY1,APBA1,SATB1,NAV1,ZBTB38,FRY,BCHE,FAM189A1,SRGAP1,SLC16A9,RNF148,DENND1C,FMNL2,ZNF629,CDH26,UNC5C,SLC37A1,MGAT4B,DCHS1,RYR2,CALCRL,OBSCN,SDK1,KHDRBS2,TEX15,ADAMTS3,NCR3LG1,THBS4,FAT1,CDH17,CLMN,IQSEC2,DHCR7,TCTN2,DOCK1,CELSR3,GPR65,RGS20,SLC7A2,SEZ6L2,LCP2,COL14A1,DOCK2,SEMA6A,CBLN1,PCLO,ZSCAN5A,ASNS,PDZD8,GPRIN1,TACC2,COL25A1,DACT1,STARD4,ZNF521,EEPD1,MAP7,NBEA,STEAP3,GULP1,MET,DNAH5,NTNG1,SEMA6C,SP140L,FZD1,GLI1,DPP10,VNN2,SSH3,COL6A2,ADCY1,PRKCQ,TTC28,DOCK5,FGFR1,ZNF569,ISG20,ZNF396,SMAD3,ARMC4,RANBP2,KPNA3,GBP1,PTPRS,ALG11,MBOAT2,NR3C2,PURG,CTNND2,OR51B5,TENM1,RUSC2,ESRP1,NKAIN2,RGS7,PPP2R3A,NEDD4,NEO1,NKX6-1,ATXN7L1,TECPR1,MAP1A,TSC22D1,TFAP2A,RALGAPA2,MYO6,GFI1,FKBP14,ZFP36L2,KIAA1211,FES,PFKFB4,RIN2,ARHGEF28,RAB6B,CACNA1E,ATP11A,C3orf70,ZFPM2,TLR6,MAP1B,RERE,MKX,EBF1,PTPRC,GPR37,SUGT1,ICA1,DOCK7,ZNF214,GNAO1,SVIL,KIAA0513,DLG2,TBC1D4,MMP16,FILIP1,LARP1,ATP1A3 |
| 2.464e-06 | -12.91 | nasopharyngeal_carcinoma | COSMIC cancer mutations | nasopharyngeal_carcinoma | 1462 | 195 | 17385 | 1698 |
ARHGAP26,EXPH5,UGT8,ACVR1,TTC39B,PPFIBP2,C20orf194,ANKRD18A,CADM2,MGAT5B,PRKCA,KIAA1217,EYA4,LGI2,SIPA1L2,RPS6KA2,DNAH6,PPFIA2,ANKFN1,CHRDL1,KIAA1614,CTTN,NEB,TBC1D8,PGBD5,LAMP3,ERGIC1,COL4A3,ALDH1L2,ANK2,LRRK2,NFIA,TMEM200C,CR2,EFHC1,ROR1,FGF17,ENPP1,GPRC5B,ENPP6,MAP2,P4HA2,ALDOA,TNFRSF1A,PIK3C2B,DSEL,UNC5B,TMEFF2,MAGI2,KCNV1,FN1,TBC1D1,STXBP6,LAMC3,TJP1,CHSY1,APBA1,SATB1,NAV1,ZBTB38,FRY,BCHE,FAM189A1,SRGAP1,SLC16A9,RNF148,DENND1C,FMNL2,ZNF629,CDH26,UNC5C,SLC37A1,MGAT4B,DCHS1,RYR2,CALCRL,OBSCN,SDK1,KHDRBS2,TEX15,ADAMTS3,NCR3LG1,THBS4,FAT1,CDH17,CLMN,IQSEC2,DHCR7,TCTN2,DOCK1,CELSR3,GPR65,RGS20,SLC7A2,SEZ6L2,LCP2,COL14A1,DOCK2,SEMA6A,CBLN1,PCLO,ZSCAN5A,ASNS,PDZD8,GPRIN1,TACC2,COL25A1,DACT1,STARD4,ZNF521,EEPD1,MAP7,NBEA,STEAP3,GULP1,MET,DNAH5,NTNG1,SEMA6C,SP140L,FZD1,GLI1,DPP10,VNN2,SSH3,COL6A2,ADCY1,PRKCQ,TTC28,DOCK5,FGFR1,ZNF569,ISG20,ZNF396,SMAD3,ARMC4,RANBP2,KPNA3,GBP1,PTPRS,ALG11,MBOAT2,NR3C2,PURG,CTNND2,OR51B5,TENM1,RUSC2,ESRP1,NKAIN2,RGS7,PPP2R3A,NEDD4,NEO1,NKX6-1,ATXN7L1,TECPR1,MAP1A,TSC22D1,TFAP2A,RALGAPA2,MYO6,GFI1,FKBP14,ZFP36L2,KIAA1211,FES,PFKFB4,RIN2,ARHGEF28,RAB6B,CACNA1E,ATP11A,C3orf70,ZFPM2,TLR6,MAP1B,RERE,MKX,EBF1,PTPRC,GPR37,SUGT1,ICA1,DOCK7,ZNF214,GNAO1,SVIL,KIAA0513,DLG2,TBC1D4,MMP16,FILIP1,LARP1,ATP1A3 |
| 2.488e-06 | -12.90 | CHEN_METABOLIC_SYNDROM_NETWORK | MSigDB lists | CHEN_METABOLIC_SYNDROM_NETWORK | 1140 | 159 | 17377 | 1707 |
LGR4,VAMP8,NDRG2,ENAH,SLCO3A1,STK24,LGI2,TUBB4A,FBXO32,RPS6KA2,KCNN2,PMAIP1,TMEM86A,PLTP,TLR4,PTPRE,PDGFRB,ABCC4,WLS,GDPD1,LRMP,COTL1,BATF,SESN1,CA13,EML1,GSN,AK1,NCKAP1L,ITGBL1,PLK2,UNC5B,TYRO3,MOCOS,GNG12,ALOX5AP,LGALS3,CHCHD7,TBC1D1,SLK,UBASH3B,SCD,CHSY1,WDFY4,ADSSL1,MCOLN2,NUMBL,CA2,PIK3AP1,ABCA5,OPN3,ADCY6,CADPS2,DENND1C,STXBP1,LRP12,IL17RD,SPATA6,STAT4,PACSIN3,FHL2,MAFB,NPC2,STEAP1,CACHD1,ADAMTS3,MATN2,SLC2A6,HK2,RAB31,RNF122,PLA2G4A,BTC,LPCAT2,GPR65,ARHGAP22,MSR1,FAM198B,SPATS2L,LACC1,LCP2,COL14A1,DOCK2,UBTD2,CDS1,FAM131B,CD53,CCDC120,SPEG,EPB41L3,ZDHHC6,ZNF521,GATM,DOCK8,SUSD3,EVL,NECAB1,TMEM43,PTPN6,TRAM1L1,C3orf52,ATF3,VIM,TTC28,TBC1D16,BATF3,ENTPD1,MSC,RNF217,WFS1,ABI3,PAM,RGS10,RCN3,SUSD4,LRRC27,HEY1,CCDC148,CD276,BLVRB,EPS8,TNFSF13B,RASSF8,RAB11FIP5,PRKCD,AFAP1L2,TBC1D9,SYK,SMPDL3A,FES,CES3,B4GALT6,RIN2,SH3BP2,AGPAT4,PTPN13,SYBU,LITAF,RASA3,PRICKLE1,CTTNBP2NL,NPDC1,GPLD1,HOMER3,GALNT3,PTPRC,CD37,ICA1,MYADM,FBN1,PRCP,PLXDC2,SRD5A3,PIP5KL1,SLC1A5,B4GALT7,ATP1A3,SLC43A1,ABCG1 |
| 2.569e-06 | -12.87 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP | 183 | 39 | 17377 | 1707 |
EPHA3,UGT8,HEBP1,UGDH,XYLT1,SLC12A6,ABHD4,DDR1,SATB1,SLC30A4,PAIP2B,KMO,PPFIBP1,MARCH3,TSPAN13,KLF9,SCN3A,TRDMT1,VAV3,BCL7A,SH3BP2,CR2,OBSCN,PLEKHA1,EXOG,INTS6,SKAP1,TTC28,DSP,SESN1,IRS2,GALNT3,SMAD3,BACH2,PRCP,SPRY4,NR3C2,ZNF235,PHC1 |
| 2.569e-06 | -12.87 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP | 183 | 39 | 17377 | 1707 |
BCL11B,IL32,SIDT1,ST6GAL1,ITGA6,GATA3,NPM1,STAT5B,KIF21B,PRKCA,FKBP11,NELL2,ABLIM1,ASNS,TGFBR3,FHIT,PJA1,PTPRCAP,MAST4,RASGRP1,PRKACB,EVL,KLHL3,STAT4,ARID5B,ATF7IP2,FASN,PRKCQ,SKAP1,PLEKHB1,DEXI,BACH2,KIAA0355,AKT3,TBC1D4,MLLT3,PKIA,DOCK9,PHC1 |
| 2.598e-06 | -12.86 | GARY_CD5_TARGETS_UP | MSigDB lists | GARY_CD5_TARGETS_UP | 447 | 75 | 17377 | 1707 |
RBFOX2,LDLR,PKP2,TUBE1,STAT5B,KIF21B,ABHD6,AARS,CYP51A1,ASNS,PMAIP1,ALDOC,POU2F2,SYNGR3,CTH,SUSD3,CD55,SLC3A2,GARS,SESN2,ATF4,PDK1,PTPN6,NFE2L1,BNIP3L,INTS6,WARS,SLC7A1,INSIG1,GPR160,P4HA1,DBP,UST,CARS,RGS16,ENO2,TBC1D1,CMTM8,OPHN1,CBS,ARL2,SCD,PKN1,PHGDH,RPL13A,DDIT4,HMGCS1,SLC7A11,MSMO1,PCK2,ESD,ZFP36L2,HMGCR,NOS3,FOXN3,MGAT4B,VLDLR,FASN,MARS,CCNG1,NPC2,FAM162A,LEPR,CEBPB,CD37,TIFA,FGR,MYADM,INHBE,DYNC2LI1,UACA,SQLE,SLC1A5,DHCR7,SLC43A1 |
| 2.598e-06 | -12.86 | CAGTATT,MIR-200B,MIR-200C,MIR-429 | MSigDB lists | CAGTATT,MIR-200B,MIR-200C,MIR-429 | 447 | 75 | 17377 | 1707 |
PHACTR3,TRIM2,SCAMP1,RECK,NPM1,NOVA1,NCS1,HECTD2,PCDH7,CCNJ,PLS3,PPM1E,KCTD15,RPS6KA2,AKAP7,SLC16A2,DACT1,REEP1,ACVR2A,MARCKS,TLN2,JAKMIP3,MYT1,PRKACB,CYP1B1,GPM6A,KLHL3,TRAM1L1,NFIA,PRKAR2B,SESN1,ZNF711,HLF,KLF12,MAP2,PLK2,NCOA7,PAM,TMEFF2,MBOAT2,CTNND2,EFNB2,BCL11B,FN1,ZCCHC24,LRP4,EPS8,YPEL2,SCD,CREB5,FOXG1,MTUS1,CNTN4,GATA2,TSC22D1,KLF9,ERRFI1,IGSF3,DUSP1,ESRRG,PTPN13,VLDLR,FERMT2,PRDM1,SNAP25,ZFPM2,LEPR,NEGR1,NAP1L5,KIAA0355,RND3,ADAMTS3,GEM,OCLN,PKIA |
| 2.604e-06 | -12.86 | MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 137 | 32 | 17377 | 1707 |
MYO1D,CELSR3,PLAG1,KIF5C,IGF2BP2,SATB1,CBLN1,ARHGAP44,COL27A1,CDS1,KCNJ4,EOMES,CHRNA5,PLTP,SMAD6,NTNG1,RNF152,PTPRU,JPH1,FHL2,ELMOD1,TMTC4,WNT11,ATOH1,CCDC85A,KHDRBS2,B4GALNT3,GALNT3,ATP7B,NXPH4,NEUROG2,FRMD5 |
| 2.631e-06 | -12.85 | GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | MSigDB lists | GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS | 987 | 141 | 17377 | 1707 |
LGR4,FGF13,GATA3,PRKCA,RAC3,F3,RND2,RAP2A,CTTN,SLIT2,TBC1D8,NKX2-1,CYP1B1,GCNT2,COL4A3,DCC,LRRK2,ROR1,GPC6,GSN,WIPF3,CCBE1,ALDOA,SEMA3C,PPARGC1A,NRP1,VASH2,TPM1,MAGI2,LZTS1,MLLT3,MEF2C,UST,SEMA6B,RUNX2,FN1,CELSR1,PTPRD,TBC1D1,BVES,ST6GAL1,SPINK5,CHN1,NUMBL,SEMA4F,GATA2,MYC,TSPAN12,BNIP3,FMNL2,RIMS2,NOS3,EPB41L5,BDNF,DISC1,RHOQ,MYO10,BAIAP2,TBC1D2,CSF1,THBS4,HOXD13,SEMA3A,CDH2,SIX2,EPHA3,ID1,DNM3,CELSR3,AKAP5,PLXNA2,NTRK3,SEMA6A,PPP1R9A,TBC1D30,CD53,TBC1D19,EPB41L3,PDZD8,DACT1,BCL6,DAB2IP,MARCKS,SNAI2,SEMA6C,FZD1,GLI1,PHLDB2,SSH3,MYLK3,ADM2,FZD4,PREX1,WNT11,SYNJ2BP,AMIGO1,TBC1D16,FGFR1,WARS,BCL11A,SMAD3,CXCL10,PRKCB,PTK7,GBP1,WWTR1,HGF,BMPR1A,ATG5,HEY1,TNIK,WASF3,BMPR2,ROBO2,LRP4,EPS8,OVOL2,PKN1,PPP2R3A,NEDD4,NKX6-1,FOXP2,TFAP2A,SGK1,PRICKLE2,FES,VEGFC,MSX1,RAPGEF2,PRICKLE1,FERMT2,MAP1B,DKK1,DDAH1,FGR,MYADM,XBP1,BMP4,PAX9,SHOX2,FOXA1 |
| 2.649e-06 | -12.84 | GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_3H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 190 | 40 | 17377 | 1707 |
PLA2G4A,AMOTL1,ALOX5AP,LGR4,IL15,LPCAT2,KCTD12,ABHD4,GDPD5,PCLO,PLS3,RAB11FIP5,ASNS,MCF2L,TSC22D1,GSTM3,KIAA1614,PROS1,CTTN,PLTP,IGFBP3,SKAP2,DSTN,LRRK2,YAP1,CTTNBP2NL,HTR7,CACHD1,MSC,TIFA,DOCK7,GNB4,RAI14,DLG2,MAPK13,VASH2,FNBP1L,TTC39A,CTNND2,HEY1 |
| 2.676e-06 | -12.83 | regulation of cytoskeleton organization | biological process | GO:0051493 | 505 | 81 | 17256 | 1658 |
EPHA3,PRKN,ID1,FGF13,TMSB15A,RHOD,GPR65,HDGFL3,NPM1,ADD2,NTRK3,RAC3,PPP1R9A,SCIN,TUBB4A,ARHGEF10L,RND2,PPM1E,CTTN,MET,SLIT2,NEB,PDGFRB,FER,PHLDB2,SSH3,EVL,MYLK3,TMEM67,DSTN,PREX1,WNT11,JAM3,SNCA,GNAI1,SMAD3,RANBP2,GSN,WIPF3,MAP2,NCKAP1L,PLK2,MAP9,PAM,ARHGAP28,TMOD2,TPM1,TMEFF2,NRP1,MID1,MEF2C,CHMP4C,PRKAA2,TENM1,CELSR1,CKAP2,RHOBTB1,EPS8,ARL2,SORBS3,GPSM2,PFN2,SPIRE1,FHOD3,ARHGAP44,FSD1,MAP1A,PRKCD,SH3PXD2B,FES,PAK1,SYNPO2,RHOQ,PXN,ASAP3,BAIAP2,MAP1B,PLEKHH2,MYADM,RND3,CTSV |
| 2.723e-06 | -12.81 | WOO_LIVER_CANCER_RECURRENCE_UP | MSigDB lists | WOO_LIVER_CANCER_RECURRENCE_UP | 100 | 26 | 17377 | 1707 |
EPHA3,DBN1,QSOX1,EVL,ENO2,EFHC1,PFN2,DDR1,SEMA6A,FGFR1,ZNF354A,PLAGL1,ALDOA,HK2,RGS10,SEMA3C,MARCKS,GEM,MYO6,SLIT2,COL9A2,DDIT3,IGFBP3,FZD1,LAMP3,MEF2C |
| 2.747e-06 | -12.81 | MODULE_2 | MSigDB lists | MODULE_2 | 371 | 65 | 17377 | 1707 |
TRIM2,ACSL1,CFH,UGDH,LDLR,RTN1,EPB41L3,TGFBR3,CFHR1,BCL6,SERPINH1,CPE,SLIT2,GATM,PDGFRB,CYP1B1,IGFBP3,COL6A2,CAP2,ATF3,RARRES2,TMEM47,FGFR1,INSIG1,WWTR1,LAMB1,MAOA,GRB10,TPM1,SV2B,GNG12,IGFBP6,ENO2,FN1,ITGA6,ATP9A,EPS8,BLVRB,KIF5C,DYNC1I1,SATB1,PHLDA2,MTUS1,DDIT4,ABLIM1,MSMO1,PCBP4,SMTN,TBC1D9,NCAM1,FADS1,CRIM1,PTPN13,NR4A1,PDE8A,SNAP25,LEPR,ZIC1,PTPRC,CD37,FBN1,FAT1,GEM,DDIT3,MME |
| 2.788e-06 | -12.79 | ATGTACA,MIR-493 | MSigDB lists | ATGTACA,MIR-493 | 304 | 56 | 17377 | 1707 |
PCDH18,SV2B,RASAL2,FGF13,GTF2IRD1,GABRG2,RASL11B,COBLL1,ENAH,TJP1,ZIC2,SNX9,PFN2,ARHGAP44,FHOD3,TRPS1,SIPA1L2,ZNF362,HMGCS1,REEP1,NBEA,DAB2IP,PDE4D,FIGN,VGLL4,FMNL2,LRP12,CHSY3,BCL7A,MARK1,LCA5,KDM5B,FZD4,SOX21,ESRRG,JPH1,PREX1,ADCY1,EFNA3,MFSD6,MBNL2,MAP1B,ZIC1,ZNF711,PCGF2,SVIL,DLG2,HS3ST3B1,CDH2,TBC1D4,OSBPL6,KIF1B,CTNND2,DOCK9,MAST1,MEF2C |
| 2.814e-06 | -12.78 | GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | MSigDB lists | GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 912 | 132 | 17377 | 1707 |
UGT8,ACVR1,GATA3,PRKCA,TRPS1,SKI,TYMP,TGFBR3,EOMES,LRRC6,DLX6,ITGB3,SLIT2,PRKACB,PDGFRB,NKX2-1,CYP1B1,ABCC4,WLS,ANK2,ACVR2B,DYRK1B,HPSE,CCBE1,SEMA3C,TMOD2,UNC5B,NRP1,TPM1,MEF2C,EFNB2,LATS2,CELSR1,FN1,ITGA6,TJP1,BBS9,TTC30B,FHOD3,ABLIM1,LRP6,TSPAN12,ZNF385A,NOS3,EPB41L5,ENAM,DISC1,SH2D2A,SPATA6,DCHS1,FHL2,TTC30A,SMARCD3,CALCRL,OBSCN,SDK1,MMP15,HEYL,WDR19,DYNC2LI1,EGFL7,FNBP1L,SIX2,ID1,TCTN2,ST14,CELSR3,ARHGAP22,PLXNA2,RGS20,COL18A1,NRXN1,PIBF1,CBLN1,EPB41L3,BCL6,DAB2IP,DNAH5,SNX10,SNAI2,PERP,FZD1,INTU,MYLK3,TMEM67,ADM2,PTPN6,NKX3-2,WNT11,JAM3,FGFR1,WARS,ARMC4,SMAD3,IFT81,NRG3,PTK7,ITGA2,LAMB1,KLF5,BMPR1A,COBL,HEY1,BMPR2,FZD8,SLC12A6,OVOL2,EPHB1,PPP2R3A,HOPX,EHD3,TFAP2A,FIG4,DYNC2H1,SYK,DUSP1,VEGFC,B9D1,VAV3,SLC40A1,MSX1,NR4A1,PRICKLE1,LEPR,HOXA1,DKK1,GPLD1,TMEM237,PRCP,XBP1,BMP4,FOXA1 |
| 2.845e-06 | -12.77 | ENGELMANN_CANCER_PROGENITORS_UP | MSigDB lists | ENGELMANN_CANCER_PROGENITORS_UP | 45 | 16 | 17377 | 1707 |
SFXN1,CD55,CDC14B,GALNT6,FAT1,SLC2A6,SLC7A5,LMCD1,FHL2,GSTM3,RASD1,DLX2,GEM,MAST4,GDPD5,IGFBP3 |
| 2.854e-06 | -12.77 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | 177 | 38 | 17377 | 1707 |
FARP1,PDE1B,ZHX3,GALNT6,FBXO4,BACE1,UGDH,MCTP2,IL13RA1,ABHD4,DDR1,SATB1,TPD52L1,HMGCS1,SLC30A4,MARCH3,TSPAN13,SCN3A,VAV3,BCL7A,USP2,ATP11A,ACVR2B,EXOG,DOCK5,SKAP1,DSP,SESN1,GALNT3,SMAD3,PRCP,PLK2,HEYL,FAT1,PIK3C2B,SPRY4,ZNF235,STOM |
| 2.854e-06 | -12.77 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN | 177 | 38 | 17377 | 1707 |
ZHX3,MYO1B,MCTP2,ENAH,SATB1,RNF141,SLC30A4,PAIP2B,PPFIBP1,BCL6,RALGAPA2,NBEA,TRPC1,KLF9,SP140L,VAV3,ALDH2,TBC1D8B,STRADB,PDE8A,ARHGAP32,PLEKHA1,CD40,SAV1,SKAP1,SESN1,ATP10D,CA13,DCBLD2,ZNF711,BACH2,GPR160,GNB4,KCNG1,MAPK13,DISP1,NR3C2,MEF2C |
| 2.854e-06 | -12.77 | GSE22886_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_TCELL_VS_BCELL_NAIVE_DN | 177 | 38 | 17377 | 1707 |
RHOBTB1,FBXO4,MYO1B,COBLL1,IL13RA1,COLEC10,DDR1,NIPSNAP3B,SLC9A7,TIAM2,TBC1D19,HMGCS1,SEMA4F,BACE2,KMO,FRAS1,PDE10A,MARCH3,TSPAN13,GATM,COL9A2,SCN3A,BCL7A,GPM6A,USP2,TAF4B,DSP,ATP10D,BCL11A,ENTPD1,ATPAF2,CLMN,SEMA3C,PIK3C2B,TNFSF4,MID1,RAB30,MEF2C |
| 2.854e-06 | -12.77 | AKT_UP.V1_DN | MSigDB lists | AKT_UP.V1_DN | 177 | 38 | 17377 | 1707 |
PLA2G4A,MOCOS,RECK,HEBP1,BLVRB,ASS1,CBS,KCTD12,IL13RA1,SATB1,TPD52L1,TNFRSF19,SLCO3A1,GAS1,FHOD3,FKBP11,EFEMP1,CHN2,FBXO32,HPS1,ZDHHC6,GHR,NCAM1,FANK1,PLTP,ZNF385A,EIF4E3,CAP2,SMARCD3,C1R,CDC42BPA,BEX4,IRS2,ID3,PDLIM3,ITGBL1,MATN2,SLC7A5 |
| 2.910e-06 | -12.75 | regulation of cellular component biogenesis | biological process | GO:0044087 | 907 | 129 | 17256 | 1658 |
JCHAIN,NPM1,PRKCA,SNX9,RAC3,TUBB4A,ARHGEF10L,PPM1E,PMAIP1,HRK,CTTN,TLR4,SLIT2,IL1RAP,TBC1D8,GPM6A,LRRK2,FEZ1,TRIM9,GSN,INSIG1,WIPF3,MAP2,NCKAP1L,PLK2,TNFRSF1A,ARHGAP28,ERCC5,TMOD2,OXTR,TPM1,NRP1,TMEFF2,MEF2C,CHMP4C,PTPRD,TBC1D1,STXBP6,SLK,SORBS3,TJP1,GPSM2,PFN2,RPL13A,SPIRE1,FHOD3,FLRT3,STXBP1,EPB41L5,PAK1,BDNF,RHOQ,SLITRK2,MYO10,SLITRK5,BAIAP2,TBC1D2,RIPOR2,ADGRB3,PMEPA1,DYNC2LI1,CDH17,PLD1,FNBP1L,EPHA3,PRKN,ID1,DNM3,RHOD,TMSB15A,GPR65,ADD2,NTRK3,NRXN1,CBLN1,PPP1R9A,TBC1D30,SCIN,TBC1D19,UNC13B,DACT1,ADGRL1,DAB2IP,MET,HSPA2,SNAI2,SSH3,FER,PHLDB2,MYLK3,EVL,NOP53,PREX1,WNT11,AMIGO1,TBC1D16,WARS,SNCA,SMAD3,PTPRJ,KLF5,ATG5,COBL,TENM1,ROBO2,BIK,EPS8,CLSTN2,ARL2,SLX1B,EPHB1,ADGRB2,LRRN1,PRKCD,GTF2F2,SH3PXD2B,SMAD6,FES,PXN,SYNPO2,RAPGEF2,ASAP3,RACK1,TLR6,DKK1,MYADM,MPP7,NPHP1,OCLN |
| 2.943e-06 | -12.74 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_I | 107 | 27 | 17385 | 1698 |
GARS,KLHL13,THSD4,NKAIN2,AIG1,LRRC49,ZFPM2,NAALADL2,DOCK2,HMCN1,ATP10D,FSTL5,ARHGAP44,NEGR1,TPK1,CDS1,GNAI1,NRG3,NACC2,PLXDC2,PDE10A,PRKG1,RNF130,NRP1,TBC1D9,MAGI2,KIAA1549 |
| 2.969e-06 | -12.73 | pancreas | COSMIC cancer mutations | pancreas | 16982 | 1683 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,FHAD1,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,EEPD1,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,CHSY3,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 3.009e-06 | -12.71 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP | 164 | 36 | 17377 | 1707 |
MXI1,LPAR2,BMPR2,ITPRIP,ATP8A1,UBASH3B,ITGA6,XYLT1,YPEL2,ABHD13,TRPS1,BAG3,RALGPS2,TSC22D1,SGK1,TOX,FHIT,VWA5A,DUSP1,VNN2,VAV3,PTPN13,EFHC2,ST6GALNAC3,PLEKHA1,TTC28,HEG1,GABARAPL1,ZNF711,IRS2,NAP1L5,ARHGAP21,BACH2,PELI2,WDR19,PCSK5 |
| 3.011e-06 | -12.71 | regulation of supramolecular fiber organization | biological process | GO:1902903 | 334 | 59 | 17256 | 1658 |
TENM1,PRKN,ID1,FGF13,TMSB15A,CKAP2,GPR65,LDLR,EPS8,ARL2,HDGFL3,ADD2,CHADL,SORBS3,PFN2,RAC3,PPP1R9A,FHOD3,SPIRE1,SCIN,TUBB4A,ARHGEF10L,PPM1E,MAP1A,PRKCD,CTTN,SH3PXD2B,MET,SLIT2,FES,PAK1,FER,SSH3,PHLDB2,SYNPO2,EVL,PXN,MYLK3,DSTN,ASAP3,PREX1,WNT11,BAIAP2,MAP1B,SNCA,SMAD3,GSN,PLEKHH2,MYADM,WIPF3,NCKAP1L,MAP2,ARHGAP28,TMOD2,TPM1,TMEFF2,NRP1,MID1,MEF2C |
| 3.020e-06 | -12.71 | SENESE_HDAC3_TARGETS_DN | MSigDB lists | SENESE_HDAC3_TARGETS_DN | 480 | 79 | 17377 | 1707 |
VAMP8,PKP2,MGAT5B,PRKCA,NUP62CL,AARS,PCLO,PCDH7,SCIN,EPB41L3,FKBP9,CDR2L,ASNS,TMEM37,TMEM120B,IL1RAP,TMEM56,CTH,GDAP1,GCA,GCNT2,NPM3,NFIA,BNIP3L,YAP1,TNS1,DOCK5,SNCA,GNAI1,SLC39A14,ITGBL1,CCBE1,PTK7,EIF4EBP1,WFS1,MAOA,TPM1,CHMP4C,GNG12,ZNF395,OTOGL,GCAT,ZCCHC24,JDP2,STXBP6,CBS,SCD,ZNF219,PHGDH,GDPD5,PHLDA2,ABLIM1,BACE2,GAS2L3,LIMCH1,FIGN,RIMS2,FES,ZNF629,PNMA2,FADS1,MN1,ARAP2,RAB3B,CRIM1,CYTH3,DCHS1,OGDHL,HEG1,CTIF,C11orf45,DPY19L2,NACC2,MPP7,MATN2,SLC7A5,PCGF2,TUFT1,SFN |
| 3.039e-06 | -12.70 | GSE7852_TREG_VS_TCONV_FAT_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_FAT_UP | 191 | 40 | 17377 | 1707 |
DMXL2,RGS16,SORBS1,JDP2,ATP8A1,ZCCHC24,MLF1,YPEL2,CYP4V2,COBLL1,TMEM170B,SNX9,HOPX,TBC1D19,ATXN7L1,GALNT1,HMGCS1,BACE2,CNKSR3,ITGB3,TSPAN13,PROS1,PCK2,NEB,DUSP1,CAP2,ATF3,PRDM1,SESN1,HERPUD1,GPLD1,ISG20,MAPKAPK2,CXCL10,HPGD,LAPTM4B,GEM,FRMD5,CSRP2,CHMP4C |
| 3.085e-06 | -12.69 | ZHANG_TLX_TARGETS_60HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_60HR_UP | 283 | 53 | 17377 | 1707 |
EFNB2,PCDH18,PCSK1N,SORBS1,DUSP8,CYP2J2,ST6GAL1,LMCD1,ABAT,P2RY1,ABHD4,MLC1,SLCO3A1,SLC19A2,DDIT4,SIPA1L2,NELL2,FBXO32,RALGPS2,OPN3,TSC22D1,VWA5A,PTPRE,PCSK6,USP2,SESN2,RNF145,PNRC1,TMEM43,NR4A1,MGST3,NFE2L1,CCNG1,BAIAP2,CTIF,GABARAPL1,TMCO3,GSN,AK1,NACC2,CSF1,WWTR1,PAM,BMP1,RAI14,ZBTB20,ERCC5,TMEFF2,APBA2,DOCK6,DDIT3,MEF2C,STOM |
| 3.094e-06 | -12.69 | V$OCT1_Q6 | MSigDB lists | V$OCT1_Q6 | 247 | 48 | 17377 | 1707 |
TCP11L2,ITPRIP,REL,PLXNA2,CADM2,NRXN1,NEDD4,PPP2R3A,SLC9A7,MTUS1,FOXP2,ZNF362,SLC7A11,LRRN1,COL25A1,FLRT3,RAB26,SLC6A15,TSPAN13,PDE4D,ETV1,RIMS2,SEMA6C,SCN3A,GAB2,BDNF,GPM6A,FZD4,STAT4,ESRRG,NFIA,SATB2,PRDM1,TCERG1L,JAM3,EBF1,TCF7L1,GPRC5B,KPNA3,KLF12,MAP2,PRKCB,MAP2K6,ZBTB20,TMOD2,DLG2,MID1,TLL2 |
| 3.103e-06 | -12.68 | TGACCTY_V$ERR1_Q2 | MSigDB lists | TGACCTY_V$ERR1_Q2 | 956 | 137 | 17377 | 1707 |
PHACTR3,CGN,KIF5A,FHDC1,NDRG2,SLC2A13,DNER,IKZF2,SLCO3A1,SLC9A7,HECTD2,PCDH7,TUBB4A,PPM1E,RPS6KA2,SLC10A7,SERINC2,MPPED2,JAKMIP2,PACSIN1,TLR4,RAPGEF5,MEIS2,ERGIC1,PNRC1,GJB2,GDPD1,NFE2L1,KCND3,KLF12,CCBE1,ALDOA,INPP5F,DIRAS1,SPRY4,PPARGC1A,NRP1,APBA2,NEUROG2,MEF2C,PCSK5,RRAGD,EFNB2,SCN5A,LRFN5,SLC25A27,OPHN1,GTF2IRD1,FAM81A,SATB1,HPCAL4,MECOM,MTUS1,CA2,CNTN4,CACNB2,TSPAN12,BNIP3,ST8SIA1,RIMS2,NDUFA4L2,BDNF,RHOQ,SH2D2A,MGST3,DCHS1,WWC1,OBSCN,STRADB,SDK1,CDC42BPA,FAM162A,SH3GL2,GSTO2,PMEPA1,C1orf21,MPP2,NXPH4,XYLT1,OTX1,FAM198B,CANX,NRXN1,RADIL,PRR7,ZFYVE9,SP8,DACT1,BCL6,SYNGR3,FAM155B,GLI1,GAPDH,TMEM43,PANK1,ADCY1,FGF12,ATF3,ATP1B1,GABARAPL1,MBOAT2,LIFR,SLC6A9,GABRG2,PKN1,RGS7,PPP2R3A,RAB11FIP5,MAP1A,PCBP4,KCNMB3,ERRFI1,C15orf41,TRPM4,RIN2,MSX1,USP2,LCA5,RAB6B,ESRRG,OGDHL,AGAP2,MAP1B,DEXI,CEBPB,CD37,ID3,MYADM,NACC2,RND3,MCC,DLG2,DDIT3,FOXA1,SNPH,TLL2,ATP1A3 |
| 3.132e-06 | -12.67 | chr10q26 | MSigDB lists | chr10q26 | 83 | 23 | 17377 | 1707 |
MTG1,DOCK1,SFXN4,CTBP2,LHPP,PLEKHA1,TCERG1L,MGMT,DHX32,IKZF5,PDZD8,TACC2,ZDHHC6,ATRNL1,CPXM2,BNIP3,AFAP1L2,INPP5F,JAKMIP3,LRRC27,PTPRE,FANK1,GFRA1 |
| 3.147e-06 | -12.67 | V$E4BP4_01 | MSigDB lists | V$E4BP4_01 | 205 | 42 | 17377 | 1707 |
PRKAA2,SIDT1,RBFOX2,PRDM8,CREB5,SEL1L3,IKZF2,EEF2,PDZD8,GRHL1,FUT9,PRELID1,TSC22D1,PRKG1,PCK2,VGLL4,MED12L,UNC5C,GPM6A,ERGIC1,USP2,TUBA1A,RNF145,CRIM1,ESRRG,ELMOD1,PRICKLE1,CALCRL,ATF3,ZDHHC14,PLCB1,HERPUD1,NEGR1,SMAD3,ZNF711,TMEM154,SH3GL2,PMEPA1,MAP2K6,PELI2,MPP2,OSBPL6 |
| 3.147e-06 | -12.67 | V$CART1_01 | MSigDB lists | V$CART1_01 | 205 | 42 | 17377 | 1707 |
LRFN5,TCP11L2,FGF13,PRSS12,KLHL13,CADM2,CREB5,ZNF219,MTUS1,ARHGEF10L,EFEMP1,FOXP2,PPM1E,ZNF362,KCTD15,UNC13B,IKZF5,BACE2,CHRDL1,MPPED2,BCL6,SLC16A9,BEND4,MOXD1,MYT1,RIMS2,MEIS2,ESRRG,MSRB3,SLITRK5,PRDM1,ROR1,ZFPM2,MBNL2,BCL11A,PTPRC,KIAA0355,PELI2,TMEM117,DLG2,MID1,MEF2C |
| 3.148e-06 | -12.67 | cardiac chamber development | biological process | GO:0003205 | 161 | 35 | 17256 | 1658 |
SCN5A,ACVR1,BMPR2,GATA3,PKP2,ADAMTS6,OVOL2,ADGRG6,TGFBR3,SMAD6,CPE,FZD1,TMEM65,ANK2,FHL2,NSD2,RYR2,SMARCD3,WNT11,PRDM1,ZFPM2,SAV1,DSP,HEG1,HEYL,PTK7,SEMA3C,BMP4,BMPR1A,TPM1,NRP1,SHOX2,MEF2C,HEY1,PCSK5 |
| 3.165e-06 | -12.66 | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | 233 | 46 | 17377 | 1707 |
RUNX2,TTC39B,SCAMP1,SEC24D,RECK,ELOVL7,RHPN2,IL13RA1,KIAA1217,CD7,SLCO3A1,IL18R1,EPCAM,IGF1R,SEMA4F,EOMES,ABI3BP,DSG2,NBEA,CTTN,CERS4,SLCO4C1,RRAS2,CPE,PTPRE,GATM,LRP12,TBC1D8,VAV3,GCA,GPM6A,STAT4,PRKCQ,PRDM1,DSP,ISG20,ENTPD1,ENPP1,TMEM154,TRIM34,P4HA2,GPR160,ZBTB20,NRP1,TNFRSF17,CDH2 |
| 3.188e-06 | -12.66 | adrenal_cortical_carcinoma | COSMIC cancer mutations | adrenal_cortical_carcinoma | 2311 | 288 | 17385 | 1698 |
DOC2A,MYCBP2,PPP4R4,TCP11L2,GRIK2,ATP8A1,CA8,PCDH7,IKZF5,DNAH6,MEIS2,DCC,KLHL3,KLHL4,LRMP,FEZ1,F12,MFSD6,ZDHHC14,INTS6,PYCR1,AHRR,ENPP6,MAP9,SEMA3C,ERCC5,ZBTB20,TANC2,DNHD1,SPOCK3,PTPRD,ZHX3,SCN8A,ITGA6,ST6GAL1,MRPL22,WDFY4,ADSSL1,GRPEL2,MTUS1,MCOLN2,SYCP2,FRY,KIAA1671,NOVA2,SRGAP1,GRIP1,CADPS2,ALPK1,FIGN,MOXD1,FAM155A,GPR161,CHRM3,QSOX1,MYO10,COL4A4,FASN,RYR2,ZNF558,TEX15,RIMKLB,PMEPA1,MATN2,DHCR7,ACSM3,DOCK9,DNM3,ST14,CCDC110,MYO1B,MSR1,PLXNA2,BEGAIN,PKP2,TBC1D30,TIAM2,NELL2,TMEM53,RNF150,ALDOC,ALDH1L1,SCRN1,NBEA,DAB2IP,ARL4D,RAB27B,DNAH5,GATM,KCNB2,SCN3A,DOCK8,C3orf67,TRAM1L1,WNT11,PRKCQ,DSP,ATP10D,DCBLD2,ENTPD1,GYPC,TDO2,LAMB1,INPP4B,PAM,GRB10,HOXB9,CCDC148,FARP1,WDR17,EDA2R,ATP9A,FZD8,ESRP1,KIF5C,P2RY1,ZNF219,RGS7,GDPD5,IRX5,SOAT2,AFF2,GPR155,MED12L,PDLIM7,TRPM4,BCL7A,ARHGEF28,SYNPO2,PTPN13,CTTNBP2NL,SKAP1,NSD1,PCDHB7,TERT,CLDN12,SLCO5A1,PGM2L1,NEK11,SVIL,MYOM2,OCLN,TLL2,EXPH5,KIF5A,PTPN21,FAM13A,HMCN1,CEP85L,SIPA1L2,SEC16B,KCNN2,GRHL1,ABI3BP,MARVELD2,POF1B,COL19A1,SLC2A12,JAKMIP2,TLN2,MYRIP,NEB,ZNF391,SLC3A2,COL4A3,ABCC4,SPOCD1,ANK2,GDPD1,RNF44,SERGEF,NT5DC2,TCF7L1,HPSE,OXTR,MAGI2,RRAGD,BCL11B,MOCOS,LGALS3,STXBP5L,SEC24D,CYP4V2,GALNT13,CHSY1,SPINK5,DOK5,PCDHB14,EFEMP1,KIAA1958,KIAA0895,ZNF354A,SEMA4F,BCHE,FRAS1,EBF4,NCEH1,ZNF629,PAK1,UNC5C,PCDH10,IL17RD,SH2D2A,PPFIA4,OBSCN,SDK1,LHPP,PRDM1,LDHD,TBC1D2,NAP1L5,GRIK4,KIAA0355,FAT1,HK2,NXPH4,XKR4,OSBPL6,EML5,CFH,DOCK1,PLEKHA5,NTRK3,TNKS1BP1,PPP1R9A,PCLO,SEMA6A,DOCK2,ZSCAN5A,COL22A1,UNC13B,SETDB2,PPFIBP1,LHX6,FABP6,MYO3B,MYH15,MET,CLVS2,IGFBP3,PTPN6,ACO1,CHRNA6,VIM,DOCK5,JAM3,WARS,IFT81,NRG3,PTPRJ,MAOA,PTPRS,CTNND2,CNTN1,TENM1,PCDH18,ARHGEF11,CLGN,CLSTN2,PRDM8,TECPR1,EHD3,STC2,TSC22D1,KIAA0319,PRICKLE2,IPCEF1,PCK2,IQGAP3,ATP2B1,KIAA1211,MICAL2,HNF4G,NR4A1,GRID1,MARS,ARHGAP32,FNDC3A,RERE,MAP1B,DPY19L2,GPR37,MPP7,SLC7A5,UACA,KIAA0513,ZNF808,FILIP1 |
| 3.228e-06 | -12.64 | cell-cell junction | cellular component | GO:0005911 | 442 | 72 | 18223 | 1724 |
CGN,AMOTL1,SORBS1,FGF13,PKP2,CADM2,LCP2,TNKS1BP1,CTNNA2,CD53,EPCAM,EPB41L3,MARVELD2,KAZN,LIN7A,POF1B,SCN2A,PERP,DBN1,FZD4,TMEM65,PTPRU,PTPN6,GJB2,ANK2,ABCC2,ATP1B1,TMEM47,DSP,JAM3,MAGI3,GJC1,PATJ,PTPRJ,GYPC,PTK7,OXTR,MAGI2,SCN5A,BMPR2,BVES,STXBP6,ITGA6,TJP1,MLC1,SCN1B,FLRT3,DSG2,PRKCD,MPDZ,IQGAP3,YBX3,JAM2,FGFR4,PDLIM7,PAK1,CDH26,PARD3B,RAPGEF2,CYTH3,CDC42BPA,SKAP1,STEAP1,BAIAP2,HEG1,MYADM,MPP7,FAT1,CLDN12,CDH2,NPHP1,OCLN |
| 3.246e-06 | -12.64 | FOSTER_TOLERANT_MACROPHAGE_DN | MSigDB lists | FOSTER_TOLERANT_MACROPHAGE_DN | 388 | 67 | 17377 | 1707 |
ARHGAP26,PLA2G4A,IL15,COL18A1,IL13RA1,LCP2,UBTD2,SLCO3A1,RAC3,KREMEN1,CDS1,TLR3,SETDB2,PPFIBP1,SNX10,FZD1,GCA,GCNT2,EVL,RNF125,CD40,SLC39A14,RANBP2,PTPRJ,GYPC,KPNA3,GNB4,NCOA7,TNFSF4,RGS16,TBC1D1,PTPRD,REL,UBASH3B,JDP2,GPSM2,INPP1,COL27A1,HOPX,MTUS1,OTUD1,SLC30A4,CA2,MCF2L,SGK3,ERRFI1,FMNL2,SLC45A3,CEBPD,RIN2,MYO10,SPATA13,FNDC3A,TMCO3,MYADM,PLAGL1,MPP7,PLOD2,RND3,PMEPA1,CSF1,AKT3,SLC2A6,RAI14,UACA,IQSEC2,SLFN5 |
| 3.254e-06 | -12.64 | SWEET_LUNG_CANCER_KRAS_DN | MSigDB lists | SWEET_LUNG_CANCER_KRAS_DN | 411 | 70 | 17377 | 1707 |
SORBS1,ACSL1,CFH,RECK,MYO1B,NDRG2,BCL6B,KCTD12,ENAH,SLCO3A1,FKBP9,CFHR1,ACVR2A,MARCKS,PLTP,CPE,PDGFRB,ANTXR2,COL6A2,TUBA1A,PLEKHA1,RARRES2,SESN1,NT5DC2,SNCA,GSN,GBP1,GNB4,LAMB1,WWTR1,PAM,SEMA3C,ZBTB20,LIFR,HEY1,MEF2C,CNTN1,EFNB2,LATS2,IGFBP6,PTPRD,TJP1,SATB1,TNFRSF19,BMP6,HOPX,ABLIM1,CA2,CACNB2,ACTA2,LIMCH1,TSPAN13,MPDZ,KLF9,MYO6,SMAD6,DUSP1,CES3,BDNF,GSTM2,CYTH3,FERMT2,CALCRL,LEPR,ID3,MATN2,SLC7A5,SHOX2,PTGES,PKIA |
| 3.289e-06 | -12.62 | PENG_LEUCINE_DEPRIVATION_UP | MSigDB lists | PENG_LEUCINE_DEPRIVATION_UP | 132 | 31 | 17377 | 1707 |
CARS,BCL7A,SLC3A2,GARS,ALDH2,ATF4,ATP8A1,ST6GAL1,LRMP,BNIP3L,NFE2L1,ASS1,MARS,KIF21B,PHGDH,AARS,GPLD1,RERE,WARS,ISG20,PYCR1,CEBPB,SLC7A1,ASNS,EIF4EBP1,EIF1,BMP1,PCK2,SLC1A5,PSPH,SLC43A1 |
| 3.290e-06 | -12.62 | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP | MSigDB lists | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP | 178 | 38 | 17377 | 1707 |
CXCR5,SERINC5,JDP2,UBAC2,CEBPA,NTRK3,ABAT,IKZF2,GDPD5,EPDR1,TMEM86A,BCL6,GFI1,STXBP1,SNX10,ZNF518B,RBMS2,SNAI2,SKAP2,KLHL4,GSTM4,MPP1,PTPN13,MEF2B,TLR6,CPEB1,ISG20,CXCL10,SH3RF1,ADAMTS3,SLC22A15,PLD1,DHCR7,RNF157,DOCK6,OSBPL6,SLC43A1,LPP |
| 3.290e-06 | -12.62 | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_UP | 178 | 38 | 17377 | 1707 |
BCL11B,MRC2,IL32,ENO2,CFH,TSPAN15,PSTPIP2,ITGA6,GATA3,KIF5C,P2RY1,LCP2,CHN1,FRY,SLC22A18,ATRNL1,JAKMIP2,IPCEF1,CAND2,CYP1B1,MICAL2,MYLK3,PXN,STAT4,DCHS1,EFHC2,PHACTR2,PRKCQ,PLS1,ZFPM2,AK1,HLF,GBP1,PAM,INPP4B,NEUROG2,MLLT3,RRAGD |
| 3.334e-06 | -12.61 | cell adhesion | biological process | GO:0007155 | 875 | 125 | 17256 | 1658 |
EPHA3,MPZL3,SORBS1,ID1,ACVR1,CELSR3,CNTNAP3,RHOD,COL18A1,PKP2,ADD2,CADM2,NRXN1,BCAN,PRKCA,COL14A1,DDR1,RADIL,CBLN1,CTNNA2,CHST10,PCDH7,EPDR1,EPCAM,PPFIA2,PPFIBP1,ITGB3,ADGRL1,COL19A1,CTTN,TLN2,PERP,CYP1B1,FER,ITGB7,COL6A2,COL4A3,PTPRU,FZD4,WISP3,PTPN6,NLGN4X,FEZ1,ATP1B1,AMIGO1,DSP,JAM3,ENTPD1,LMLN,GYPC,HPSE,ITGBL1,NCAM2,PTK7,ITGA2,LAMB1,PTPRS,NRP1,CTNND2,CNTN1,LPP,EFNB2,TENM1,TYRO3,PCDH18,INPPL1,IL32,FN1,ROBO2,CELSR1,PTPRD,BVES,ITGA6,STXBP6,UBASH3B,CLSTN2,LAMC3,SELL,SORBS3,GAS6,EPHB1,APBA1,NEO1,PCDHB14,SLC7A11,CNTN4,SCN1B,FLRT3,DSG2,SCARF2,LRP6,MPDZ,NCAM1,JAM2,SMAD6,STXBP1,SYK,FES,EPB41L5,PCDH10,CDH26,PXN,PODXL2,PARD3B,DCHS1,FERMT2,SDK1,FNDC3A,PEAK1,BAIAP2,NEGR1,RIPOR2,PCDHB7,EDA,FAT4,RND3,FBN1,THBS4,CLDN12,FAT1,EMILIN2,CDH17,EGFL7,CDH2,NPHP1 |
| 3.354e-06 | -12.61 | DEFA1 (defensin alpha 1) | protein interactions | 1667 | 87 | 24 | 17029 | 1718 |
TMEM67,CEMIP2,CNTNAP3,LDLR,EDEM3,PLXNA2,COL18A1,TJP1,NPC2,COL14A1,TGFBR3,EEF2,CHRNA5,BCHE,CTSV,LAMB1,BMP1,NXPH4,MOXD1,LIFR,SLIT2,LRP12,CACNA2D1,IGSF3 |
| 3.407e-06 | -12.59 | GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | MSigDB lists | GO_CENTRAL_NERVOUS_SYSTEM_DEVELOPMENT | 848 | 124 | 17377 | 1707 |
UGT8,ID1,FGF13,AKAP5,RBFOX2,OTX1,PLXNA2,NDRG2,ABAT,NRXN1,BCAN,DNER,NOVA1,RAC3,AARS,CBLN1,CTNNA2,SKI,BAG3,EOMES,KCNAB1,TACC2,LHX6,DAB2IP,MARCKS,SYNGR3,ZNF488,TLR4,DNAH5,SLIT2,POU3F3,GLI1,NKX2-1,FZD1,INTU,VNN2,SMAD9,FZD4,DCC,WLS,LRRK2,NLGN4X,SATB2,VIM,EFHC1,ATOH1,FGFR1,EML1,TSKU,IRS2,ARMC4,GSN,NRG3,MAP2,GNB4,LAMB1,PAM,PTPRS,SERPINI1,DLX2,OXTR,BMPR1A,NRP1,PPARGC1A,CTTNBP2,CNTN1,TYRO3,BCL11B,WASF3,PCDH18,GNG12,SCN5A,CELSR1,BMPR2,ROBO2,LAMC3,PRDM8,ZIC2,EPHB1,PHGDH,FOXG1,GDPD5,CHD5,HPCAL4,PGAP1,DDIT4,NKX6-1,FOXP2,NUMBL,HMGCS1,CNTN4,SLC7A11,SCN1B,GATA2,AFF2,TFAP2A,PRKG1,LRP6,DYNC2H1,ATP2B1,RAX,DISC1,UNC5C,MSX1,RAPGEF2,VLDLR,SLITRK5,AK4,MAFB,CLN5,PLCB1,ZIC1,DKK1,RERE,ID3,DOCK7,FAT4,SH3GL2,GNAO1,BMP4,CDH2,SEMA3A,ATP2B4,SNPH |
| 3.461e-06 | -12.57 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | 569 | 90 | 17377 | 1707 |
CREB3L2,CFH,SYT12,ASS1,NRN1,CTBP2,SLC7A2,SEZ6L2,FAM13A,ABHD6,SEMA6A,PCDH7,NELL2,GRHL1,BCL6,PDE4D,RAB27B,CPE,IGFBP3,PDK1,PNRC1,TMEM43,FAM84A,GJB2,BNIP3L,RNF125,TNS1,TMEM47,SAV1,ASPH,TTC28,TSKU,BCL11A,ITGA2,NCOA7,AHNAK2,PAM,P4HA1,MAOA,KLF5,TNFSF15,UNC5B,TC2N,PSPH,RRAGD,HEY1,MXI1,ZNF395,ENO2,SEC24D,PLAG1,COL4A5,ADSSL1,SATB1,COL27A1,GAS1,PCDHB14,OTUD1,BACE2,STC2,EBF4,RALGAPA2,BNIP3,CEBPD,IGSF3,DUSP1,PCSK6,CARD6,KDM5B,FOXN3,ARID5B,VLDLR,LITAF,PDE8A,CCNG1,FNDC3A,SLC46A3,HERPUD1,RERE,CEBPB,CACHD1,RPL28,PLAGL1,PLOD2,RAB31,HK2,NXPH4,IQSEC2,TESC,CACNA2D1 |
| 3.480e-06 | -12.57 | lung-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-bronchioloalveolar_adenocarcinoma | 786 | 116 | 17385 | 1698 |
EPHA3,DMXL2,NEK10,ACVR1,ARHGAP22,PPFIBP2,COBLL1,CHUK,CEBPA,NTRK3,GRK6,PRKCA,DDR1,STK24,CYP26A1,COL22A1,SPEG,RPS6KA2,PPFIBP1,RPS6KL1,MYO3B,ACVR2A,BEND4,MET,ZNF365,PRKACB,PDGFRB,SUSD3,FER,TNK2,PRAME,MYLK3,MARK1,PDK1,ACVR1C,NR6A1,LRRK2,ADCY1,SATB2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,JAM3,ATP10D,FGFR1,GJC1,DYRK1B,TRIM9,PRKCB,PLK2,PTK7,ERN1,INPP4B,RGS10,MAPK13,SERPINI1,BMPR1A,APBA2,CTNND2,MAST1,CRYL1,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,FN1,GALNT13,COL4A5,PKN1,EPHB1,PPP2R3A,SOAT2,IGF1R,ADCK1,BCHE,AFF2,PRKCD,SGK3,PRKG1,CPXM2,SGK1,ALPK1,SH3PXD2B,PRR16,SYK,KIAA1211,RIMS2,CAND2,FES,MED12L,PAK1,FGFR4,DISC1,NUAK2,OBSCN,FERMT2,STRADB,ATP11A,CDC42BPA,GPLD1,CTIF,MAPKAPK2,GRIK4,NSD1,TRIB3,DDAH1,FGR,PKN3,AKT3,MAP2K6,NEK11,GRIN2D,MMP16 |
| 3.480e-06 | -12.57 | bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | bronchioloalveolar_adenocarcinoma | 786 | 116 | 17385 | 1698 |
EPHA3,DMXL2,NEK10,ACVR1,ARHGAP22,PPFIBP2,COBLL1,CHUK,CEBPA,NTRK3,GRK6,PRKCA,DDR1,STK24,CYP26A1,COL22A1,SPEG,RPS6KA2,PPFIBP1,RPS6KL1,MYO3B,ACVR2A,BEND4,MET,ZNF365,PRKACB,PDGFRB,SUSD3,FER,TNK2,PRAME,MYLK3,MARK1,PDK1,ACVR1C,NR6A1,LRRK2,ADCY1,SATB2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,JAM3,ATP10D,FGFR1,GJC1,DYRK1B,TRIM9,PRKCB,PLK2,PTK7,ERN1,INPP4B,RGS10,MAPK13,SERPINI1,BMPR1A,APBA2,CTNND2,MAST1,CRYL1,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,FN1,GALNT13,COL4A5,PKN1,EPHB1,PPP2R3A,SOAT2,IGF1R,ADCK1,BCHE,AFF2,PRKCD,SGK3,PRKG1,CPXM2,SGK1,ALPK1,SH3PXD2B,PRR16,SYK,KIAA1211,RIMS2,CAND2,FES,MED12L,PAK1,FGFR4,DISC1,NUAK2,OBSCN,FERMT2,STRADB,ATP11A,CDC42BPA,GPLD1,CTIF,MAPKAPK2,GRIK4,NSD1,TRIB3,DDAH1,FGR,PKN3,AKT3,MAP2K6,NEK11,GRIN2D,MMP16 |
| 3.568e-06 | -12.54 | Collagen formation | REACTOME pathways | R-HSA-1474290 | 93 | 24 | 10287 | 971 |
COL9A3,COL6A2,COL4A3,COL4A4,ITGA6,COLGALT2,COL18A1,COL4A5,COL14A1,COL27A1,COL22A1,ADAMTS3,PLOD2,COL25A1,P4HA2,CTSV,BMP1,P4HA1,COL19A1,PCOLCE2,LOXL4,SERPINH1,COL9A2,TLL2 |
| 3.618e-06 | -12.53 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3756 | 441 | 17385 | 1698 |
ARHGAP26,MYCBP2,ACVR1,DUSP8,TTC39B,DNAJC3,PPFIBP2,GATA3,NPM1,STAT5B,ADAMTS6,CADM2,PRKCA,SNX9,RAC3,STK24,HECTD2,NOS1AP,SKI,PCDH7,TRPS1,BAG3,FBXO32,PMAIP1,PPFIA2,RAP2A,RAB26,PPP2R2B,NKX2-1,SMAD9,ACVR1C,NR6A1,TGFA,LRRK2,DNAJC6,LRMP,BNIP3L,DEPTOR,PRKAR2B,ACVR2B,SAV1,ZDHHC14,INTS6,GNAI1,AHRR,HLF,PLK2,RASGRF2,ALDOA,ADRB1,BBC3,MAPK13,ERCC5,INPP5F,DIRAS1,SERPINI1,SPRY4,UNC5B,LPP,MEF2C,CARS,GNG12,LATS2,INPPL1,ALOX5AP,PTPRD,ITGA6,MLF1,ST6GAL1,BTBD9,GPSM2,TNFRSF10C,TNFRSF19,FOXG1,BBS9,CHD5,GAS1,MECOM,CHN1,NAV1,BNIP1,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,SRGAP1,MPDZ,TOX,ALPK1,LOXL4,SAMD13,RIMS2,HMGCR,RNF152,PTCH2,RPL26,PNP,PLEKHA8,STAT4,RAPGEF4,SMARCD3,HIP1,CDC42BPA,PLCB1,FAM162A,TMEM74,DHX32,MMP15,PMEPA1,ADAMTS3,PKN3,HOXD13,SPRED3,FBXO27,DHCR7,SMYD3,AMPD1,PLA2G4A,EPHA3,RNF144A,RHOD,RGS20,CHUK,GRK6,COLEC10,DDR1,COL14A1,ZFYVE9,RNF150,SPEG,DACT1,ALDOC,STARD4,PDE4D,ARL4D,RAB27B,SERPINH1,SNX10,FZD1,GAB2,TRDMT1,MYLK3,GAPDH,PDK1,FZD4,ATF7IP2,PREX1,PRKCQ,ATF3,RAB38,PYGO1,FGFR1,GJC1,IRS2,CXCL10,ARHGAP21,IKZF3,PRKCB,CCNA1,INPP4B,TNFSF15,GRB10,BMPR1A,MID1,RAB30,HACE1,FARP1,MXI1,EDA2R,FZD8,PLAG1,BIK,IPO5,ARL2,HERC5,GAS6,PKN1,EPHB1,RGS7,INPP1,TSPAN17,NEDD4,RGS17,MCF2L,PCBP4,GAS2L3,GHR,SGK3,SMAD6,SPRY2,ZFP36L2,FES,BCL7A,VAV3,ALDH2,PXN,RAB6B,MCF2L2,RAPGEF2,PTPN13,AK4,RASA3,SNTB1,GPLD1,CEBPB,PTPRC,TRIB3,NSD1,ID3,FGR,TERT,GNAO1,AKT3,XBP1,NEK11,PIP5KL1,BMP4,HK1,TNFRSF17,DDIT3,BTRC,FOXA1,TRIM2,TRIM16,PTPN21,ITPR2,NOVA1,IKZF2,KREMEN1,FKBP11,ARHGEF10L,RND2,PPM1E,FKBP9,RPS6KA2,LRRC6,AKAP7,ITGB3,HRK,CTTN,PTPRE,ENO1,ETV1,RAPGEF5,RASGRP1,PDGFRB,PRKACB,ITGB7,TNK2,SESN2,CD55,MARK1,PNRC1,YAP1,CR2,ROR1,COTL1,PLEKHA1,SGK2,BATF,RNF44,SESN1,SERGEF,PLEKHB1,DYRK1B,TRIM9,AK1,KCNMB4,HPSE,GNB4,ERN1,TNFRSF1A,NCOA7,PIK3C2B,TNFSF4,PPARGC1A,MLLT3,RRAGD,KCNV1,PRKAA2,BCL11B,RGS16,RUNX2,RHOBTB1,JDP2,FBXO4,SATB1,DOK5,HSPA12B,DDIT4,RNF141,NUMBL,IGF1R,GATA2,LRP6,BNIP3,RNF148,PTPRCAP,FBXL2,SNX7,PAK1,FGFR4,MID2,RHOQ,MSTN,SPATA13,PPFIA4,SDC3,OBSCN,MAFB,DUSP9,STRADB,PRDM1,KHDRBS2,MAPKAPK2,HK2,RAB31,PTPRN2,PLD1,RNF122,FNBP1L,NKX2-8,SFN,CXCR5,NEK10,ID1,AKAP5,DOCK1,PLEKHA5,PSTPIP2,ARHGAP22,HECW2,RNF24,BCL6B,NTRK3,PPP1R9A,SLC22A17,CDC14B,TACC2,RPS6KL1,PPFIBP1,MYO3B,ZNF521,BCL6,ACVR2A,MDH1B,MET,POU2F2,HSPA2,SNAI2,GLI1,SUSD3,FER,PTPRU,PTPN6,ACO1,RNF125,VIM,RARRES2,CD40,FBXO36,FRK,TPK1,BCL11A,SMAD3,RANBP2,PTPRJ,BACH2,TRIM34,KPNA3,PTK7,EIF4EBP1,ITGA2,RGS10,DUSP19,PTPRS,RNF130,SEPT5,LIFR,CTNND2,CNTN1,MAST1,HEY1,TNIK,DYRK3,BMPR2,ENO2,ARHGEF11,GRB14,REL,NLRP14,TNFSF13B,IGF2BP2,RASD1,USP30,PPP2R3A,FOXP2,CHN2,PRKCD,RASD2,TRIM3,SGK1,PCK2,RRAS2,SYK,FKBP14,TNFRSF11A,DUSP1,DLGAP1,RIN2,PPP1R3D,CARD6,RAB3B,USP2,HNF4G,NR4A1,ESRRG,FOXN3,CRIP2,CYTH3,SYBU,LITAF,NUAK2,MARS,AGAP2,CCNG1,ARHGAP32,MGMT,DKK1,ADAMTS17,SUGT1,RND3,MAP2K6,FMO4,SH3BGRL2,PAX9,GEM,RNF157,PTGES,MMP16 |
| 3.644e-06 | -12.52 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN | 420 | 71 | 17377 | 1707 |
PLA2G4A,IL15,PRSS12,RBFOX2,MYO1B,RGS20,PKP2,SPATS2L,F3,PLS3,MET,KLHL29,IL1RAP,SNAI2,PERP,PHLDB2,SKAP2,RNF145,WLS,TGFA,YAP1,COTL1,DOCK5,ATP10D,DCBLD2,GNAI1,GJC1,IRS2,SMAD3,GBP1,PTK7,CCNA1,WWTR1,BMP1,KLF5,NRP1,GNG12,IGFBP6,TBC1D1,ITGA6,UBASH3B,IGF2BP2,GPSM2,SLC1A3,NDFIP2,SEL1L3,INPP1,GAS1,ZBTB38,DSG2,SGK1,SLC6A15,RRAS2,FMNL2,SPRY2,CEBPD,SNX7,CARD6,STAT4,C1R,MBNL2,HOXA1,TMEM154,RND3,AKT3,SVIL,KIF1B,SFN,MME,DCBLD1,DIRC2 |
| 3.708e-06 | -12.51 | SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN | 78 | 22 | 17377 | 1707 |
VAV3,EVL,CELSR1,SIDT1,CLGN,SLC27A2,GALNT6,BIK,DEPTOR,GATA3,PSD3,COL4A5,NPDC1,SLC19A2,CDS1,MAP9,LIN7A,GSTM3,RAB27B,TBC1D9,MAST4,FOXA1 |
| 3.711e-06 | -12.50 | signal transduction | biological process | GO:0007165 | 4964 | 557 | 17256 | 1658 |
ARHGAP26,PDE1B,GRIK2,DNAJC3,NPM1,CEBPA,STAT5B,CHAC1,DOCK3,CA8,SKI,BAG3,TGFBR3,PMAIP1,RAP2A,RAB26,TSHR,CPE,SMAD9,DCC,CAP2,WLS,TGFA,LRRK2,PRKAR2B,FGF17,INTS6,WIPF3,ADRB1,ARHGAP28,BBC3,INPP5F,DIRAS1,MEF2C,LATS2,GNG12,ITGA6,SLK,TJP1,GPSM2,HPCAL4,CHN1,FLRT3,SRGAP1,NCAM1,TSPAN9,GFRA1,CHRM3,LRP12,ZNF385A,BDNF,MYO10,STAT4,ARID5B,FHL2,HIP1,CALCRL,RYR2,OR11H4,ARRDC4,SH3GL2,CDH17,INHBE,TRPC3,SHTN1,DOCK9,BTC,ZNF516,IL13RA1,MAPK4,GRK6,NRXN1,LCP2,CDS1,GPR15,PLPP1,TLR3,CHRNA5,DACT1,CNKSR3,RTKN2,RAB27B,PERP,DOCK8,FZD1,MYLK3,ADM2,FZD4,KCNH5,ADCY1,WNT11,RAB38,FGFR1,MAGI3,IRS2,ARHGAP21,CXCL10,GPR160,WFS1,APELA,WWTR1,INPP4B,TNFSF15,HOXB9,LRRC27,RAB30,CGB2,EDA2R,ROBO2,FZD8,ESRP1,CD276,GAS6,P2RY1,PKN1,EPHB1,ZNF219,TSPAN17,NEO1,MCF2L,BHLHA15,PCBP4,GHR,MYO6,ZFP36L2,FES,VEGFC,TRPM4,B9D1,RAB6B,RAPGEF2,RASA3,GAREM1,PTPRC,GALNT3,TRIB3,PLPPR2,AKT3,GNAO1,XBP1,NEK11,BMP4,DOCK6,FOXA1,BTRC,FGF13,LILRB1,NDRG2,ITPR2,FAM13A,RND2,RPS6KA2,ITGB3,TBC1D32,TLR4,RAPGEF5,ITGB7,KCNIP3,GCNT2,ATF4,MARK1,COL4A3,ANK2,PLPP2,CR2,PLEKHA1,BATF,PLEKHB1,TSKU,SPNS1,INHBC,TCF7L1,INSIG1,GNB4,ERN1,TNFRSF1A,PIK3C2B,ADGRA3,ADGRL2,TYRO3,PRKAA2,RGS16,RUNX2,UBASH3B,RASL11B,DOK5,IL18R1,EFEMP1,NUMBL,SEMA4F,IGF1R,PDE10A,LRP6,ADCY6,BNIP3,PAK1,DPYSL5,FGFR4,UNC5C,BTNL9,HOMER2,EFNA3,STRADB,OBSCN,PDE8A,GPR19,BAIAP2,MAPKAPK2,GRIK4,HEYL,CSF1,PLD1,SEMA3A,SFN,ID1,DOCK1,AKAP5,RBFOX2,RHPN2,OR51B4,NTRK3,TNKS1BP1,RADIL,PCLO,SEMA6A,PPP1R9A,SLC22A17,BCL6,ADGRL1,SCN2A,SNAI2,GLI1,CTH,EVL,LRRC8B,FGF12,CHRNA6,VIM,GSTO1,FRK,SMAD3,NRG3,PTPRJ,PTK7,GBP1,ITGA2,MAOA,HGF,CTNND2,HEY1,CNTN1,TENM1,LPAR2,IL32,BMPR2,GRB14,PAK5,NLRP14,APBB1,MCTP2,GABRG2,RASD1,ARHGAP44,RASD2,GTF2F2,SGK1,PRICKLE2,TSPAN13,SYK,DUSP1,MOB1B,NUAK2,LITAF,PRICKLE1,FERMT2,HOMER3,DKK1,CD37,DDAH1,DOCK7,FAT4,SLC1A5,PTGES,CGN,ACVR1,LANCL3,LGR4,GATA3,PRKCA,RAC3,NCS1,STK24,MOK,CHRDL1,ATRNL1,RCAN3,DCDC1,ACVR1C,WISP3,NR6A1,DEPTOR,BNIP3L,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,GNAI1,GPR150,NCKAP1L,PLK2,RASGRF2,SEMA3C,MAPK13,UNC5B,NRP1,SPOCK3,EFNB2,INPPL1,MRC2,CELSR1,PTPRD,GABRB2,DHCR24,OPHN1,TNFRSF10C,TNFRSF19,RALGPS2,PIK3AP1,MYC,PRKG1,OPN3,SREBF1,GRIP1,TSPAN12,MAST4,GPR161,RIMS2,IGSF3,PTCH2,DISC1,RPL26,DCHS1,RAPGEF4,VLDLR,CDC42BPA,PLCB1,DAGLA,PMEPA1,PKN3,PELI2,WDR19,MPP2,EPHA3,PCSK1N,AMOTL1,RASAL2,TCTN2,RHOD,GPR65,PLXNA2,CHUK,DDR1,ZFYVE9,TIAM2,ASNS,SHF,DAB2IP,PDE4D,GAB2,PDK1,PREX1,PRKCQ,ATF3,ATOH1,PYGO1,ATP1B1,DCBLD2,SNCA,ISG20,PATJ,HTR7,BEX3,PRKCB,ASIC1,MAP3K21,HPGD,GRB10,BMPR1A,MAPK10,NR3C2,MID1,HACE1,IGFBP6,EPS8,GPR180,GABRR2,NDFIP2,RGS7,INPP1,NEDD4,ADGRB2,RASSF8,GPR155,SGK3,PRKG2,SMAD6,VAV3,ARHGEF28,GSTM2,ARAP2,PXN,SH3BP2,MPP1,GUCY1A2,SKAP1,GPLD1,CEBPB,FGR,OR2T33,MCC,TUFT1,GRIN2D,LRRK1,TNFRSF17,DDIT3,LARP1,ACSL1,HEBP1,DNER,KREMEN1,F3,ARHGEF10L,EPCAM,EPHB6,OR2W3,SLIT2,IL1RAP,PRKACB,PDGFRB,RASGRP1,CYP1B1,TNK2,SESN2,SKAP2,CAPN5,YAP1,ROR1,SGK2,GRK3,SERGEF,GSN,GPRC5B,OXTR,PPARGC1A,TNFSF4,MAGI2,GPR63,BCL11B,FN1,RHOBTB1,ATP6V1E2,CD7,ADGRG6,DDIT4,CA2,INAVA,CEBPD,NOS3,GPR176,IL17RD,RHOQ,MSTN,SH2D2A,EDEM3,DUSP9,WWC1,HERPUD1,PLAGL1,ADGRB3,RAB31,NXPH4,TMEM117,DISP2,CREB3L2,CXCR5,SORBS1,CELSR3,IL15,ARHGAP22,CANX,DOCK2,CD53,UNC13B,PDZD8,CDC14B,RPS6KL1,ACVR2A,GULP1,FHIT,MET,FER,ANTXR2,PTPRU,PTPN6,SYNJ2BP,CD40,DOCK5,BCL11A,TRIM34,EIF4EBP1,RGS10,DISP1,LIFR,MAST1,OR51B5,TNIK,TSPAN15,ARHGEF11,REL,LRP4,TNFSF13B,COL4A5,NOTUM,BMP6,MCU,SYDE2,NKX6-1,CHN2,STC2,PRKCD,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,MSX1,RAB3B,HNF4G,CRIM1,NR4A1,ESRRG,GRID1,ARHGAP32,TLR6,LEPR,GPR37,TIFA,EDA,RND3,MAP2K6,UACA,GEM,MAP3K20,IL9R,NPHP1 |
| 3.742e-06 | -12.50 | SABATES_COLORECTAL_ADENOMA_DN | MSigDB lists | SABATES_COLORECTAL_ADENOMA_DN | 263 | 50 | 17377 | 1707 |
EPHA3,PRKAA2,WASF3,C2orf88,SV2B,FN1,CFH,SETBP1,KIF5C,KCTD12,NRXN1,SPINK5,PCDH7,RTN1,MCOLN2,EFEMP1,EPB41L3,CA2,CNTN4,BCHE,ABI3BP,GHR,RUNDC3B,CHRDL1,CNNM2,NAP1L3,TBC1D9,JAM2,DUSP1,DPP10,UNC5C,RAB3B,SYNPO2,USP2,GCNT2,ANK2,LRRK2,CR2,NLGN4X,TNS1,GPC6,CD37,PRKCB,ENPP6,DSEL,TMOD2,TNFRSF17,LIFR,XKR4,AMPD1 |
| 3.788e-06 | -12.48 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP | 179 | 38 | 17377 | 1707 |
BCL11B,TNIK,SERINC5,ACVR1,IL32,TRIM16,RNF144A,GALNT12,ITGA6,GATA3,STAT5B,LCP2,KIF21B,PRKCA,NELL2,BAG3,FHIT,IPCEF1,MAST4,PXN,SH2D2A,TMEM43,STAT4,PRKCQ,SKAP1,PLEKHB1,AKT3,RGS10,INPP4B,KIAA0513,SVIL,HK1,APBA2,TBC1D4,MLLT3,ATP2B4,DOCK9,PCSK5 |
| 3.843e-06 | -12.47 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_DN | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_DN | 114 | 28 | 17377 | 1707 |
PHACTR3,CCDC126,SCN5A,DNM3,SORBS1,PODXL2,ALDH2,CACNG3,EDA2R,DOCK1,JDP2,FAM84A,OGDHL,CLSTN2,YAP1,RASD1,GPC6,ENTPD1,AKAP7,PIK3AP1,HPS1,PCGF2,SLC16A9,SMAD6,XKR4,CSRP2,SLC43A1,GLI1 |
| 3.897e-06 | -12.46 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | 186 | 39 | 17377 | 1707 |
NBL1,SIDT1,BMPR2,ST6GAL1,RHPN2,GAS6,SPATS2L,SLC1A3,DDR1,IKZF2,FAM110B,HECTD2,MTUS1,LGI2,SCN1B,GPR155,MAP7,VGLL4,LRP3,CARD6,RNF145,WLS,NFIA,TCEAL3,PLEKHA1,ZDHHC14,TTC28,SESN1,EML1,GLCE,ARHGAP21,ICA1,GYPC,DISP1,BMPR1A,NRP1,TBC1D4,STON2,DENND5B |
| 3.897e-06 | -12.46 | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_WITH_TGFB_UP | 186 | 39 | 17377 | 1707 |
RGS16,FGF13,REL,RIMKLA,YPEL2,LRRCC1,KIF5C,NDFIP2,IKZF2,PFN2,GPR15,IGF1R,GPR155,MYO3B,MARCKS,PACSIN1,CLVS2,ZNF365,DNAH5,SLIT2,FMNL2,SNAI2,GCA,PHLDB2,CDH26,MEIS2,SKAP2,TMEM65,SLC27A2,AGPAT4,CYTH3,CRIP2,C3orf70,KCNMB4,GNB4,CLDN12,TBC1D4,FNBP1L,RRAGD |
| 3.906e-06 | -12.45 | V$SOX5_01 | MSigDB lists | V$SOX5_01 | 249 | 48 | 17377 | 1707 |
MXI1,MRC2,ID1,PRSS12,RHOBTB1,KLHL13,RBFOX2,MORC4,COL4A5,FAM117B,ZIC2,APBA1,EPHB1,NOVA1,SEMA6A,PCDH7,CCNJ,TUBB4A,FOXP2,ZNF362,CDR2L,LRRN1,MPPED2,ATRNL1,ACVR2A,EPHB6,PPP2R2B,NCAM1,ZNF365,SEMA6C,PAK1,VAV3,MARK1,NR4A1,ESRRG,ANK2,NFIA,SATB2,SKAP1,PLCB1,JAM3,BCL11A,RERE,EBF1,PELI2,DLG2,NRP1,SEMA3A |
| 3.946e-06 | -12.44 | positive regulation of signaling | biological process | GO:0023056 | 1752 | 223 | 17256 | 1658 |
CACNG3,ACVR1,LGR4,TRIM16,GRIK2,SYT12,VAMP8,LMCD1,GATA3,CTBP2,ABAT,PRKCA,STK24,NOS1AP,SKI,F3,GSDME,TGFBR3,PMAIP1,ITGB3,HRK,EPHB6,MYRIP,TLR4,RASGRP1,PDGFRB,CYP1B1,GCNT2,ATF4,SKAP2,WLS,TGFA,LRRK2,YAP1,ACVR2B,ROR1,FGF17,INHBC,GSN,GPRC5B,HPSE,CCBE1,PLK2,ERN1,ADRB1,TNFRSF1A,BBC3,TMOD2,INPP5F,DIRAS1,OXTR,NRP1,UNC5B,MLLT3,RRAGD,TYRO3,BVES,SORBS3,CHSY1,TNFRSF10C,SLC1A3,TNFRSF19,CHD5,IL18R1,MYORG,CHN1,CA2,IGF1R,PIK3AP1,LRP6,INAVA,BNIP3,STXBP1,ZNF385A,RIMS2,HMGCR,PAK1,FGFR4,RPL26,MID2,BDNF,ATP5IF1,DISC1,MSTN,SH2D2A,DUSP9,WWC1,HIP1,PDE8A,SNAP25,PLCB1,FAM162A,BAIAP2,MAPKAPK2,ADAMTS3,PELI2,CSF1,MPP2,INHBE,CDH2,SEMA3A,SFN,EPHA3,PRKN,BTC,SORBS1,NEK10,AVPI1,IL15,GPR65,CHUK,NTRK3,NRXN1,PIBF1,DDR1,TLR3,UNC13B,KMO,DACT1,SHF,ACVR2A,DAB2IP,MET,GLI1,CTH,IGFBP3,INTU,FZD4,PFKFB2,PTPN6,SHANK2,ATF3,WNT11,GSTO1,CD40,FGFR1,SNCA,IRS2,SMAD3,CXCL10,PTPRJ,PRKCB,APELA,ITGA2,MAP3K21,DUSP19,TNFSF15,HGF,GRB10,BMPR1A,DISP1,MAPK10,MID1,TENM1,TNIK,NECAB2,EDA2R,C1QTNF3,BMPR2,GRB14,FZD8,REL,EPS8,BIK,CLSTN2,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,TSPAN17,BMP6,NEDD4,MCU,NEO1,NKX6-1,CHN2,PRKCD,RASD2,GHR,AFAP1L2,DYNC2H1,PCK2,IQGAP3,GFI1,TNFRSF11A,TESPA1,SYK,SPRY2,PARP9,TRPM4,VAV3,SH3BP2,GSTM2,RAB3B,MSX1,RAPGEF2,SYBU,LITAF,GAREM1,RACK1,SKAP1,TLR6,GPLD1,DKK1,GPR37,PTPRC,FGR,EDA,NACC2,TERT,MPP7,MAP2K6,AKT3,XBP1,GRIN2D,LRRK1,BMP4,SHOX2,MAP3K20,DDIT3,FOXA1 |
| 3.967e-06 | -12.44 | LEONARD_HYPOXIA | MSigDB lists | LEONARD_HYPOXIA | 46 | 16 | 17377 | 1707 |
PFKFB4,MXI1,TGFA,AK4,DDIT4,F3,P4HA2,STC2,ALDOA,HK2,SLC7A5,P4HA1,BNIP3,DDIT3,RASGRP1,DUSP1 |
| 4.092e-06 | -12.41 | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | 214 | 43 | 17377 | 1707 |
ZNF516,LPCAT2,C20orf194,NPM1,PSD3,COL4A5,FAM174B,SEMA6A,COL27A1,MECOM,ATXN7L1,ZNF827,RSL24D1,ABLIM1,IGF1R,CFHR1,MYC,DAB2IP,EPHB6,PDE4D,VWA5A,PTPRE,MAST4,SMAD6,SPRY2,RPS23,SNAI2,ATF4,PXN,ABCC4,PTPN13,THSD4,GSTO1,RNF44,SMAD3,RND3,ITGA2,PTPRN2,GRB10,RPS12,UNC5B,TESC,ABCG1 |
| 4.214e-06 | -12.38 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | 173 | 37 | 17377 | 1707 |
TCP11L2,PSTPIP2,YPEL2,LRRCC1,SLC1A3,SLC7A2,GAS6,PIBF1,TTC30B,GAS1,FHOD3,RNF150,ABLIM1,AFAP1L2,TOX,SCN3A,CEBPD,IL17RD,COL6A2,GSTM2,PNRC1,SKAP2,TDRD3,PRICKLE1,FEZ1,C1R,TTLL7,NSD1,TMEM154,PLXDC2,MATN2,EMILIN2,CLMN,ARHGAP28,BMP4,LIFR,MME |
| 4.214e-06 | -12.38 | GSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE37301_CD4_TCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 153 | 34 | 17377 | 1707 |
ANKRD13D,RNF144A,ELOVL7,MCTP2,GRK6,DDR1,DENND3,BBS9,SLCO3A1,CTNNA2,TGFBR3,TECPR1,SEMA4F,TACC2,EHD3,ITGB3,HS3ST5,SGK1,ADCY6,BEND4,ST8SIA1,PFKFB4,PDK1,MYO10,RAPGEF4,DNAJC6,PREX1,ATP1B1,OSBPL5,TNFRSF1A,HS3ST3B1,FBXO27,SLC16A10,AMPD1 |
| 4.388e-06 | -12.34 | FARDIN_HYPOXIA_11 | MSigDB lists | FARDIN_HYPOXIA_11 | 32 | 13 | 17377 | 1707 |
PFKFB4,MXI1,PDK1,IGF1R,ZNF395,P4HA2,ALDOC,BNIP3L,AK4,BNIP3,FAM162A,DDIT4,IGFBP3 |
| 4.444e-06 | -12.32 | PTCH1 (patched 1) | protein interactions | 5727 | 100 | 26 | 17029 | 1718 |
UGT8,B3GLCT,CEMIP2,CNTNAP3,ITGA6,FHL2,YAP1,COL18A1,ST6GALNAC3,PXYLP1,CHSY1,ASPH,SEMA6A,NEDD4,MYORG,ENPP1,TGFBR3,SEMA4F,MGAT1,PAM,RNF130,MOXD1,GALNT18,SLIT2,CACNA2D1,B4GALT7 |
| 4.465e-06 | -12.32 | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 187 | 39 | 17377 | 1707 |
CREB3L2,CCDC126,LATS2,JDP2,VAMP8,CYP4V2,NRN1,FAM81A,RBM11,SNX9,TBC1D30,IL18R1,HOPX,GPR15,SEMA4F,IGF1R,CNKSR3,ALDOC,GPR155,RUNDC3B,MYO3B,SMTN,CERS4,PROS1,RAPGEF5,SUSD3,ANTXR2,ALDH2,ABCC4,SMARCD3,PDE8A,NPC2,ARRDC4,BATF,CEBPB,INPP4B,TESC,CRYL1,RRAGD |
| 4.607e-06 | -12.29 | testis-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-non_seminoma | 488 | 79 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,ERGIC1,MARK1,PDK1,ACVR1C,ALDH1L2,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,SEC24D,UBAC2,PKN1,EPHB1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,NOS3,PAK1,FGFR4,PCDH10,DCHS1,NUAK2,OBSCN,STRADB,CDC42BPA,MAPKAPK2,TRIB3,FGR,TMEM237,PKN3,AKT3,MAP2K6,OSBPL5,NEK11,FILIP1,LARP1,CACNA2D1 |
| 4.644e-06 | -12.28 | large_intestine | COSMIC cancer mutations | large_intestine | 17068 | 1688 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,SLX1B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,CHSY3,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,NCS1,STK24,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 4.829e-06 | -12.24 | Cholesterol Biosynthesis | WikiPathways | WP197 | 15 | 9 | 5312 | 569 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,SQLE,DHCR7,HMGCR |
| 4.853e-06 | -12.24 | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_SAP1A_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_SAP1A_KO_DP_THYMOCYTES_UP | 174 | 37 | 17377 | 1707 |
TRIM2,FN1,ATP9A,SLC12A6,TPD52L1,CYP26A1,OTUD1,ABI3BP,ACTA2,NAP1L3,PJA1,GFRA1,SCN3A,GAB2,RWDD2A,PHLDB2,MGST3,ANK2,CAP2,ST6GALNAC3,AIG1,SYNJ2BP,CTTNBP2NL,SPATA7,GABARAPL1,ZNF711,BEX4,NRG3,NCAM2,RND3,FAT1,ITGA2,RAI14,BDH2,GRB10,SMYD3,ATP2B4 |
| 4.857e-06 | -12.24 | GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION | 787 | 116 | 17377 | 1707 |
EPHA3,BTC,NBL1,ACVR1,TRIM16,IL15,AKAP5,MSR1,GATA3,CEBPA,STAT5B,NTRK3,PRKCA,RAC3,SEMA6A,PPP1R9A,CTNNA2,SCIN,CD53,RND2,EOMES,BCL6,ACVR2A,DAB2IP,MARCKS,PACSIN1,ZNF488,SLIT2,RASGRP1,SNAI2,CTH,IGFBP3,GCNT2,MYLK3,PREX1,YAP1,FEZ1,ACVR2B,AMIGO1,RARRES2,ATOH1,SAV1,FGFR1,BCL11A,SMAD3,GPRC5B,NCKAP1L,PTK7,WWTR1,KLF5,HGF,BMPR1A,NRP1,TNFSF4,MAGI2,COBL,CNTN1,MEF2C,EFNB2,RUNX2,BMPR2,ROBO2,FN1,LGALS3,ZHX3,PTPRD,CD276,PLAG1,APBB1,OVOL2,GAS6,GDPD5,BMP6,HOPX,NKX6-1,NUMBL,CA2,SCN1B,GATA2,SGK1,SH3PXD2B,FIG4,SYK,RIMS2,FES,ZNF385A,PTCH2,TRPM4,PDLIM7,EPB41L5,VEGFC,BDNF,DISC1,PNP,RAPGEF2,VLDLR,SMARCD3,PRDM1,PLCB1,CPEB1,BAIAP2,MAP1B,DKK1,NEGR1,CEBPB,MYADM,CSF1,HEYL,XBP1,BMP4,SEMA3A,SHOX2,CDH2,TESC,SFN,FOXA1 |
| 4.874e-06 | -12.23 | EGF-like_dom | interpro domains | IPR000742 | 223 | 44 | 18492 | 1811 |
TENM1,BTC,CELSR1,CELSR3,CNTNAP3,LRP4,LDLR,LAMC3,SELL,GAS6,BCAN,NRXN1,DNER,HMCN1,EFEMP1,NELL2,FRAS1,VWDE,SCARF2,ATRNL1,LRP6,PROS1,NTNG1,SLIT2,PCSK6,TGFA,VLDLR,C1R,F12,HEG1,NRG3,FAT4,FBN1,ITGBL1,FAT1,CCBE1,THBS4,LAMB1,MATN2,BMP1,EGFL7,TMEFF2,PCSK5,TLL2 |
| 4.905e-06 | -12.23 | GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_DN | 154 | 34 | 17377 | 1707 |
SERINC5,KLF8,MXI1,FARP1,SORBS1,ATP9A,RIMKLA,SETBP1,PPP2R3A,EPCAM,HMGCS1,ASNS,IKZF5,MARVELD2,MYC,MARCH3,CCDC122,POU2F2,CPE,PNRC1,COTL1,ARRDC4,SESN1,MGMT,GABARAPL1,WARS,DYRK1B,ENTPD1,ICA1,PELI2,LAPTM4B,INPP5F,LARP1,SFN |
| 4.977e-06 | -12.21 | biological adhesion | biological process | GO:0022610 | 882 | 125 | 17256 | 1658 |
EPHA3,MPZL3,SORBS1,ID1,ACVR1,CELSR3,CNTNAP3,RHOD,COL18A1,PKP2,ADD2,CADM2,NRXN1,BCAN,PRKCA,COL14A1,DDR1,RADIL,CBLN1,CTNNA2,CHST10,PCDH7,EPDR1,EPCAM,PPFIA2,PPFIBP1,ITGB3,ADGRL1,COL19A1,CTTN,TLN2,PERP,CYP1B1,FER,ITGB7,COL6A2,COL4A3,PTPRU,FZD4,WISP3,PTPN6,NLGN4X,FEZ1,ATP1B1,AMIGO1,DSP,JAM3,ENTPD1,LMLN,GYPC,HPSE,ITGBL1,NCAM2,PTK7,ITGA2,LAMB1,PTPRS,NRP1,CTNND2,CNTN1,LPP,EFNB2,TENM1,TYRO3,PCDH18,INPPL1,IL32,FN1,ROBO2,CELSR1,PTPRD,BVES,ITGA6,STXBP6,UBASH3B,CLSTN2,LAMC3,SELL,SORBS3,GAS6,EPHB1,APBA1,NEO1,PCDHB14,SLC7A11,CNTN4,SCN1B,FLRT3,DSG2,SCARF2,LRP6,MPDZ,NCAM1,JAM2,SMAD6,STXBP1,SYK,FES,EPB41L5,CDH26,PCDH10,PXN,PODXL2,PARD3B,DCHS1,FERMT2,SDK1,FNDC3A,PEAK1,BAIAP2,NEGR1,RIPOR2,PCDHB7,EDA,FAT4,RND3,FBN1,THBS4,CLDN12,FAT1,EMILIN2,CDH17,EGFL7,CDH2,NPHP1 |
| 5.106e-06 | -12.19 | regulation of neurotransmitter levels | biological process | GO:0001505 | 309 | 55 | 17256 | 1658 |
DOC2A,PRKN,SLC6A9,PDE1B,GCAT,SYT12,ASS1,BTBD9,SLC7A2,SLC1A3,ABAT,SYT14,ZNF219,NRXN1,APBA1,KCNC4,PHGDH,PFN2,PCLO,PPP1R9A,NOS1AP,RNF180,UNC13B,BCHE,KMO,PPFIA2,LIN7A,CADPS2,MOXD1,TLR4,STXBP1,RIMS2,NOS3,CYP1B1,GLDC,RAB3B,LRRK2,PPFIA4,SNAP25,TLR6,SNCA,TRIM9,SMAD3,DAGLA,DDAH1,KCNMB4,ENPP6,ASIC1,MAOA,PTPRN2,SEPT5,TC2N,ATP2B4,MEF2C,SNPH |
| 5.109e-06 | -12.18 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_DN | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_DN | 188 | 39 | 17377 | 1707 |
CXCR5,CCDC126,ST6GAL1,LDLR,KIF5C,CEBPA,GABRR2,FAM81A,DDR1,PFN2,BAG3,TGFBR3,IGF1R,EOMES,GRHL1,BCL6,MAP7,TSPAN13,TOX,PACSIN1,ZNF518B,RASGRP1,SMPDL3A,EPB41L5,TUBA1A,PDK1,CYTH3,PANK1,PRICKLE1,PHACTR2,ATP1B1,COTL1,IFT81,PLAGL1,WFS1,SQLE,DHCR7,TESC,SLC43A1 |
| 5.153e-06 | -12.18 | nodular | COSMIC cancer mutations | nodular | 1541 | 202 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,CGN,THOC5,GRIK2,ATP8A1,LDLR,FHDC1,TNFAIP8L2,GATA3,ADAMTS6,ABAT,SNX9,CA8,HMCN1,NCS1,ARHGEF10L,LGI2,BAG3,CPVL,LRRC6,ZFYVE28,KCNS3,GSTM3,COL19A1,COG3,TLN2,VWA5A,TMEM132E,MYRIP,CPE,OR2W3,TLR4,TSHR,IL1RAP,DCC,CAP2,CR2,TCERG1L,EML1,SFXN1,SPNS1,DYRK1B,NCKAP1L,TECPR2,CCDC146,BMP1,ARHGAP28,MAPK13,UNC5B,MAGI2,SPOCK3,LZTS1,PCSK5,CARS,SV2B,LRFN5,CELSR1,SEC24D,OPHN1,SETBP1,LRRC49,TNFRSF10C,CD7,BBS9,MECOM,ABLIM1,GBGT1,CNTN4,APLF,PDE10A,HS3ST5,SMTN,LRP6,CPXM2,LIMCH1,TSPAN12,ST8SIA1,SLCO4C1,MOXD1,PRR16,CHRM3,NOS3,CDH26,DISC1,GSTM4,DCHS1,FASN,PLS1,SNAP25,CDC42BPA,SDK1,PLCB1,KHDRBS2,STEAP1,BAIAP2,BEX4,TEX15,KIAA0355,MFSD2A,EMILIN2,SH3BP4,CDH17,PTPRN2,PLD1,DHCR7,CDH2,EPHA3,AVPI1,GALNT12,BEGAIN,COBLL1,NTRK3,KIF21B,DENND3,COL14A1,DOCK2,ZSCAN5A,ZNF827,COL22A1,UNC13B,GPRIN1,TACC2,ZDHHC6,EEPD1,BCL6,MET,DNAH5,MYT1,DOCK8,KCNB2,PRAME,MYLK3,KCNH5,ADCY1,SATB2,PRKCQ,CD40,FRK,DOCK5,FGFR1,ZNF711,IQCH,RNF217,GBP1,PTPRS,SOHLH2,HGF,PLD5,CTNND2,CNTN1,OR51B5,WASF3,ANO10,PCDH18,SLC6A9,WDR17,KLHL13,GCAT,GRB14,APBB1,MCTP2,GABRG2,COL4A5,SLC12A6,RGS7,USP30,NEO1,LRRC55,ACTA2,SGK1,DHRS12,SYK,RBMS2,ATP2B1,CARD6,MICAL2,ARAP2,LRRIQ1,CLYBL,ESRRG,FOXN3,NUAK2,PALLD,MGMT,MAP1B,EBF1,PTPRC,CD37,NSD1,PCDHB7,FAT4,TERT,FBN1,MPP7,SLC7A5,MYOM2,KIF21A,OCLN,SLC43A1,ZNF235 |
| 5.188e-06 | -12.17 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | 195 | 40 | 17377 | 1707 |
ARHGAP26,ACSL1,FLVCR2,BLVRB,CEBPA,FAM198B,CHSY1,DENND3,SLCO3A1,ARHGEF10L,RTN1,EPB41L3,BCL6,SGK1,LIN7A,MARCKS,CKAP4,CEBPD,CYP1B1,VNN2,RIN2,MICAL2,PXN,GAPDH,SH3BP2,SLC36A1,MAFB,SMARCD3,DOCK5,CEBPB,ENTPD1,FGR,HPSE,NACC2,ALDOA,HK2,TNFRSF1A,KIAA0513,HK1,PCSK5 |
| 5.401e-06 | -12.13 | GO_TUBE_DEVELOPMENT | MSigDB lists | GO_TUBE_DEVELOPMENT | 543 | 86 | 17377 | 1707 |
ACVR1,ID1,LGR4,ST14,PLXNA2,GATA3,ASS1,CEBPA,DDR1,TRPS1,SKI,EPCAM,SETDB2,DACT1,ITGB3,DAB2IP,MET,SLIT2,PRKACB,POU3F3,GLI1,NKX2-1,FZD1,INTU,SMAD9,KLHL3,NKX3-2,YAP1,WNT11,ACVR2B,RARRES2,SAV1,FGFR1,SMAD3,PTK7,EIF4EBP1,KLF5,SEMA3C,OXTR,BMPR1A,NRP1,COBL,MEF2C,PCSK5,EFNB2,CELSR1,BMPR2,ROBO2,ITGA6,GPSM2,OVOL2,PHGDH,HOPX,FOXP2,GATA2,MYC,SREBF1,LRP6,ERRFI1,SMAD6,SPRY2,NOS3,EPB41L5,PAK1,MICAL2,KDM5B,DCHS1,PRICKLE1,RYR2,PRDM1,ZFPM2,HOXA1,HEG1,FAT4,CECR2,CSF1,HEYL,WDR19,HOXD13,BMP4,DHCR7,NKX2-8,SHOX2,FOXA1,BTRC,SIX2 |
| 5.412e-06 | -12.13 | cell | cellular component | GO:0005623 | 16522 | 1612 | 18223 | 1724 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,SMIM20,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,ZNF788P,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,SELENOM,LAPTM4B,HOXD13,CDH2,GVINP1,SHTN1,DOCK9,MTG1,TFCP2L1,SCAMP1,SUGCT,ABHD13,ADD2,MAPK4,GRK6,SLC19A2,PLPP1,TLR3,MAGEA3,ALDH1L1,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,LRRC27,RAB30,CGB2,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,LZTS3,OPLAH,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,PHC1,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,SEC16B,AADAT,ITGB3,TMEM143,TBC1D32,JAKMIP2,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,CR2,SESN1,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,ADGRA3,NEUROG2,TC2N,CACUL1,RRAGD,LONRF1,TYRO3,KCNV1,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,B3GLCT,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,MYH15,SNAI2,IGFBP3,RPS13,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,KIZ,BMPR2,KLHL13,PAK5,MCTP2,PRDM8,RASD1,USP30,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,SYK,ATP2B1,CES3,PCSK6,DUSP1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,PALD1,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,SLC9C1,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,HERC6,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,MYC,SCARF2,PRKG1,SREBF1,GRIP1,MAST4,FAM155A,COL9A2,GPR161,BOD1,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,WDR19,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ERG28,ASNS,ZNF438,POU5F1B,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,PATJ,ZNF711,IKZF3,POPDC3,BEX3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ADGRB2,GSAP,LRRC55,IRX5,AFF2,GPR155,RMDN2,DYNC2H1,CERS4,ERRFI1,TBC1D9,SMAD6,B4GALT6,SLC40A1,VAV3,ARHGEF28,ALDH2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,HOXA1,ZFP62,TERT,MCC,SVIL,LRRK1,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,SLC2A13,HMCN1,CHST10,F3,GSDME,ADPRHL1,EPCAM,PPM1E,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,CEMIP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,SCD,CHSY1,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,INAVA,VSIR,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,ATP5IF1,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,CATSPERE,STEAP1,HERPUD1,RIPOR2,PLAGL1,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,COL4A5,IGF2BP2,FAM117B,SLX1B,OVOL2,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,IPCEF1,TESPA1,RBMS2,PNMA2,USP2,KDM5B,HNF4G,CRIM1,SYBU,CCDC184,ASAP3,PEAK1,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,RND3,ACER2,CTSV,SLC18B1,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,PPP1R26,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,ZBED9,NKX2-1,CFAP44,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,HACD1,MSRB3,F12,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,SLK,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,ENAM,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,OR11H4,TAF4B,MBNL2,CPEB1,DHX32,BEX4,SH3GL2,CDH17,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,CHRNA5,GPRIN1,KMO,EEF1AKMT2,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,SSH3,GARS,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,PXYLP1,RAB38,TTC28,METAP1D,FGFR1,IRS2,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,LCA5,CLYBL,RAPGEF2,ELOVL3,GAREM1,RACK1,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,ASS1,HDGFL3,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FKBP9,KCNN2,KCNAB1,TCAF2,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLPP2,PLEKHA1,BATF,TCERG1L,PLEKHB1,TSKU,MAP2,P4HA2,GNB4,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,SETBP1,MLC1,IL18R1,PGAP1,KIAA1958,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,SPATA13,PPFIA4,PDE8A,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,PRKN,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CTNNA2,CYP26A1,FAM131B,RIDA,SLC22A17,ZDHHC6,LHX6,MYO3B,ADGRL1,CLVS2,SCN2A,ZNF488,GLI1,CTH,TMEM67,EVA1A,EVL,TUBA1A,UROS,NOP53,FGF12,GSTO1,RARRES2,FRK,ETNPPL,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,DLGAP1,MOB1B,MICAL2,PPP1R3D,NUGGC,LITAF,NUAK2,FNDC3A,NPDC1,MKX,MAP10,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,MYRF,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,RAC3,AARS,NCS1,STK24,MOK,SLC22A18,SLC16A2,CHRDL1,GSTM3,SP140,RCAN3,VWA5A,PACSIN1,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,DESI1,MEF2B,AGO4,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,CCDC181,ENTPD7,RASGRF2,B3GALT2,SPART,UNC5B,ZBED8,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,MYORG,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,MSMO1,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,TTYH2,COLGALT2,TTC30A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,VPS37D,PKN3,PMEPA1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,MAPK10,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CLBA1,CCNJL,ARL2,GABRR2,RGS7,SELENOP,GDPD5,SLC35G2,NEDD4,HOPX,KDM7A,RGS17,SOAT2,MGAT1,SGK3,PRKG2,RALGAPA2,SLC6A15,PHYKPL,FIG4,YBX3,GFI1,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,HYKK,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZNF714,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,PCGF2,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,TUBB4A,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,EPHB6,PTPRE,FANK1,GALNT18,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,GRK3,SERGEF,EML1,AK1,ITGBL1,NCAM2,C8orf88,NCOA7,APBA2,SLC9B1,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,ADGRG6,DDIT4,CA2,RPS11,EBF4,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,GALNT17,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,ADGRB3,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,LACC1,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,FAAP20,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,ZFPM2,MAP1B,RERE,GPR37,TIFA,MYADM,MPP7,NACC2,GCSAM,PRCP,MAP2K6,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 5.465e-06 | -12.12 | regulation of protein phosphorylation | biological process | GO:0001932 | 1423 | 186 | 17256 | 1658 |
ACSL1,ACVR1,FGF13,DUSP8,GRIK2,DNAJC3,NPM1,NDRG2,CEBPA,PRKCA,SNX9,STK24,GSDME,PPM1E,TGFBR3,ZFYVE28,RAP2A,ITGB3,EPHB6,TLR4,SLIT2,PRKACB,RASGRP1,PDGFRB,TNK2,SESN2,GCNT2,TGFA,LRRK2,DEPTOR,PRKAR2B,ACVR2B,ROR1,INHBC,ENPP1,GPRC5B,SH3RF1,NCKAP1L,ERN1,TNFRSF1A,DIRAS1,INPP5F,SPRY4,NRP1,PPARGC1A,CACUL1,TYRO3,LATS2,FN1,SLK,UBASH3B,SORBS3,TNFRSF10C,PFN2,TNFRSF19,MECOM,DDIT4,IGF1R,MYC,FLRT3,C1QL4,LRP6,ADCY6,INAVA,HMGCR,PAK1,FGFR4,MSTN,VLDLR,DUSP9,WWC1,STRADB,PDE8A,PLCB1,MAPKAPK2,PMEPA1,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,TESC,SFN,EPHA3,PRKN,ID1,NEK10,AVPI1,IL15,CELSR3,NTRK3,LCP2,TNKS1BP1,DDR1,PIBF1,PPP1R9A,TLR3,DACT1,CNKSR3,ACVR2A,DAB2IP,PDE4D,MET,HSPA2,IGFBP3,FZD1,FER,FZD4,NOP53,PTPN6,ADCY1,PREX1,WNT11,ATF3,RARRES2,SYNJ2BP,CD40,MAGI3,FGFR1,SNCA,WARS,CAMK2N1,CXCL10,NRG3,PTPRJ,GBP1,APELA,WWTR1,MAP3K21,DUSP19,TNFSF15,HGF,BMPR1A,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,LRP4,IPO5,HERC5,GAS6,P2RY1,PKN1,EPHB1,TPD52L1,BMP6,PRKCD,GHR,AFAP1L2,ERRFI1,IQGAP3,SMAD6,TNFRSF11A,SYK,SPRY2,PARP9,DUSP1,MOB1B,VEGFC,RAPGEF2,GAREM1,CCNG1,RACK1,TLR6,DKK1,GPR37,PTPRC,TRIB3,NSD1,FGR,DOCK7,MYADM,MAP2K6,LRRK1,BMP4,MAP3K20,ATP2B4,PKIA |
| 5.515e-06 | -12.11 | GO_REGULATION_OF_DENDRITE_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_DENDRITE_DEVELOPMENT | 116 | 28 | 17377 | 1707 |
DBN1,DISC1,TNIK,DNM3,ID1,PTPRD,AKAP5,DCC,RAPGEF2,VLDLR,LRRK2,PREX1,SDK1,PPP1R9A,NEDD4,BAIAP2,BCL11A,NUMBL,PLK2,RAP2A,KIAA0319,SGK1,DAB2IP,MARCKS,PACSIN1,COBL,LZTS1,MEF2C |
| 5.584e-06 | -12.10 | Prot_kinase_dom | interpro domains | IPR000719 | 481 | 78 | 18492 | 1811 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PDGFRB,PRKACB,FER,TNK2,MYLK3,MARK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,GRK3,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAP3K21,MAPK13,BMPR1A,MAPK10,MAST1,TYRO3,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,IGF1R,PRKCD,PRKG1,SGK3,SGK1,PRKG2,MAST4,SYK,FES,FGFR4,PAK1,NUAK2,OBSCN,STRADB,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,MAP2K6,AKT3,NEK11,LRRK1,MAP3K20 |
| 5.622e-06 | -12.09 | endoplasmic reticulum | cellular component | GO:0005783 | 1852 | 230 | 18223 | 1724 |
ACSL1,ATP8A1,DNAJC3,ASS1,ALG1L,ITPR2,PRKCA,ABHD4,NOS1AP,TXNDC5,CYP51A1,RTN1,FKBP9,SEC16B,SLC10A7,NDUFB8,CHRDL1,COL19A1,TMED9,RASGRP1,CYP1B1,ATL1,KCNIP3,ERGIC1,COL4A3,WISP3,WLS,TGFA,JPH1,LRRK2,LRMP,BNIP3L,NFE2L1,HACD1,MSRB3,F12,ZDHHC14,INSIG1,RASGRF2,P4HA2,ERN1,B3GALT2,PIK3C2B,TYRO3,SCN5A,ALOX5AP,FN1,SEC24D,CYP2J2,DHCR24,ELOVL7,CYP4V2,SCD,SPINK5,MLC1,PGAP1,MYORG,RNF180,GALNT1,BNIP1,SLC7A11,SEMA4F,BCHE,MSMO1,BACE2,FLRT3,SREBF1,LRP6,GRIP1,LMAN2,BNIP3,MOXD1,NCEH1,AGL,COL9A2,RPS23,CKAP4,HMGCR,FADS1,FGFR4,ENAM,QSOX1,B3GLCT,SLC37A1,SLC36A1,SLC27A2,RNF170,COL4A4,MGST3,GPSM1,EDEM3,RYR2,CALCRL,COLGALT2,SHISA2,NPC2,CLN5,HERPUD1,BAIAP2,THBS4,MFSD2A,CSF1,SELENOM,TMEM117,SQLE,PTPRN2,PLD1,DHCR7,CDH2,RNF122,OSBPL6,CREB3L2,PLA2G4A,PRKN,ELOVL4,LPCAT2,C4A,XYLT1,COL18A1,CANX,LPIN3,NRXN1,SEZ6L2,COL14A1,CYP26A1,TXNRD3,CDS1,COL22A1,ERG28,TLR3,PDZD8,ERO1B,COL25A1,REEP1,MAGEA3,ZDHHC6,ZDHHC23,PROS1,SERPINH1,SNX10,IGFBP3,ALG10B,ANTXR2,B3GALT1,COL6A2,EVA1A,TMEM67,EBPL,LRRC8B,TMEM43,CYB5R2,TRAM1L1,C3orf52,ACO1,RNF125,RAB38,ASPH,TRIQK,ATP10D,GABARAPL1,SNCA,GJC1,PEMT,WFS1,LAMB1,RCN3,ALG11,P4HA1,CYP2U1,MBOAT2,NR3C2,RETREG1,HACE1,TENM1,COL9A3,MYO1D,CLGN,BACE1,MCTP2,UBAC2,CLSTN2,COL4A5,RASD1,NOTUM,GAS6,EPHB1,NDFIP2,GDPD5,COL27A1,RPL34,SOAT2,PRKCD,STC2,SGK1,FIG4,CERS4,ESD,RRAS2,TESPA1,FKBP14,PCSK6,CES3,ULBP1,TRPM4,GSTM2,AGPAT4,RPL21,ELOVL3,ZDHHC15,ARHGAP32,ATP11A,LRAT,ILDR2,GPR37,EDA,PLOD2,FBN1,FMO4,OSBPL5,SRD5A3,XBP1,MYRF,RPL4,BMP4,CERS1,PTGES,CACNA2D1,ABCG1,ATP1A3,STOM |
| 5.630e-06 | -12.09 | breast-carcinoma-ductal_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductal_carcinoma | 15245 | 1544 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,SLC7A1,ENPP1,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,DENND1C,FIGN,MOXD1,JAM2,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,PDLIM7,TRPM4,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,PIP5KL1,BMP4,ATP2B4,CRISPLD1,PHC1,TLL2,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,CPVL,SEC16B,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,ENO1,RAPGEF5,PGBD5,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,TTC22,SESN1,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,NEUROG2,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,TMEM56,SNAI2,IGFBP3,RPS13,HRASLS,INTU,CSN2,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,PTPRS,MAOA,HGF,MBOAT2,CTNND2,HEY1,DYRK3,SLC6A9,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,CACNA2D1,PKIA,ZNF235,FAM171B,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,ZFYVE28,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,C1orf21,LRRIQ3,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,HOXA1,PLXDC2,SVIL,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,FBXO4,STXBP6,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CAND2,SNX7,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,COL4A5,IGF2BP2,FAM117B,OVOL2,FAM174B,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,CRYL1,LPP,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,TSPAN9,STXBP1,GLIS1,AGL,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,CNKSR3,COL25A1,DACT1,PJA1,FAM155B,ARL4D,SYNGR3,RAB27B,SCN3A,DOCK8,PERP,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,ATF7IP2,RAB38,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,HOXB9,C2orf88,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,PTPRC,GALNT3,ID3,TRIB3,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,SCN2A,FAM78B,GLI1,CTH,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,MICAL2,PPP1R3D,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,MYCBP2,CGN,PAGE1,ACVR1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,DACH2,RAC3,AARS,STK24,NCS1,CFHR1,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,RCAN3,VWA5A,PACSIN1,PLTP,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,SLC25A28,TNS1,ACVR2B,SAV1,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PIK3AP1,PDZD7,VWDE,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,KIAA1324L,TTYH2,TTC30A,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,PKN3,PMEPA1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,NUDT12,NELL2,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,DENND5B,RPS20,WASF3,ANO10,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,SLC6A15,FIG4,GFI1,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,NUDT17,ATP1A3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,DNER,IKZF2,ABHD4,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,GPR37,ADAMTS17,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,SLC16A10,STOM,SNPH |
| 5.699e-06 | -12.08 | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP | 155 | 34 | 17377 | 1707 |
KLHL13,PLAG1,ITGA6,APBB1,COBLL1,PHGDH,DDR1,SNX9,SATB1,ABLIM1,IGF1R,DACT1,SREBF1,NBEA,BNIP3,ALG10B,VNN2,CD55,PDK1,MPP1,NPM3,SFXN4,BNIP3L,TAF4B,SGK2,TTC28,CENPV,MPP7,GPR160,BBC3,DNHD1,APBA2,SNPH,NUDT17 |
| 5.717e-06 | -12.07 | FARDIN_HYPOXIA_9 | MSigDB lists | FARDIN_HYPOXIA_9 | 7 | 6 | 17377 | 1707 |
AK4,BNIP3,PDK1,FAM162A,ALDOC,DDIT4 |
| 5.751e-06 | -12.07 | mucosal | COSMIC cancer mutations | mucosal | 2042 | 257 | 17385 | 1698 |
THOC5,ADAL,PPP4R4,ACVR1,SIDT1,GRIK2,ATP8A1,FAM102B,ENAH,CADM2,KIAA1217,DACH2,FAAH2,CHRDL1,ATRNL1,PPP2R2B,SP140,VWA5A,CPE,GLDC,DCDC1,ACVR1C,DCC,NR6A1,ALDH1L2,LRRK2,MSRB3,TNS1,KCND3,GPC6,ENPP1,BMP1,MAPK13,INPP5F,LRFN5,PTPRD,TNFRSF19,DYNC1I1,ADSSL1,SYCP2,ABLIM1,GBGT1,SLC7A11,CNTN4,FLRT3,SLC16A9,ALPK1,MOXD1,COL9A2,CHRM3,IGSF3,SLC37A1,PNP,STAT4,FASN,KIAA1324L,CALCRL,SNAP25,OR11H4,PLCB1,SPATA7,DAGLA,XKR9,TEX15,PLEKHH2,PELI2,EMILIN2,CDH17,AMPD1,ACSM3,ADD2,PKP2,COLEC10,COL14A1,ZFYVE9,TIAM2,ALDH1L1,ZNF365,DNAH5,KCNB2,SCN3A,NPM3,KCNH5,TRAM1L1,ADCY1,NLGN4X,PRKCQ,ATP10D,FGFR1,ZNF711,ARHGAP21,WFS1,INPP4B,PLD5,CTTNBP2,NR3C2,COBL,CCDC148,WDR17,EPS8,NKAIN2,CREB5,COL27A1,AFF2,SMPDL3A,MED12L,FES,B4GALT6,ULBP1,TRPM4,TMC7,VAV3,SYNPO2,LCA5,ARAP2,ATP11A,GUCY1A2,SKAP1,GPLD1,TERT,PLXDC2,PIP5KL1,EXPH5,TRIM2,CACNG3,ACSL1,KIF5A,DNER,IKZF2,HMCN1,FSTL5,F3,EPCAM,EOMES,GRHL1,MARVELD2,ANKFN1,COL19A1,JAKMIP2,PCOLCE2,TMEM132E,TLR4,OR2W3,MYRIP,PTPRE,SLIT2,PDGFRB,SKAP2,ANK2,JPH1,ROR1,SERGEF,EML1,ITGBL1,PIK3C2B,PPARGC1A,MAGI2,APBA2,PRKAA2,FN1,SEC24D,ELOVL7,LAMC3,SETBP1,ZNF215,SORBS3,MLC1,EFEMP1,ZNF354A,LIMCH1,FAR2,NOS3,UNC5C,PODXL2,SLC27A2,SDC3,TEX9,KHDRBS2,SLC46A3,LDHD,AMDHD1,KIAA0355,PTPRN2,OSBPL6,SIX2,SORBS1,ID1,CFH,CELSR3,AKAP5,ARHGAP22,HECW2,OR51B4,SLC7A2,KIF21B,LPIN3,PPP1R9A,COL22A1,SLC22A17,TACC2,EEPD1,PROS1,SCN2A,MET,TMEM67,LRRC8B,PTPRU,TDRD3,TES,NRG3,RNF217,BACH2,GBP1,ITGA2,HGF,SUSD4,LIFR,CTNND2,MAST1,PCDH18,SLC6A9,DYRK3,BMPR2,IL32,GRB14,CLGN,GABRG2,CLSTN2,COL4A5,OVOL2,PPP2R3A,EHD3,STC2,KIAA0319,TFAP2A,SH3PXD2B,IPCEF1,IQGAP3,CES3,DLGAP1,CARD6,MICAL2,CRIM1,MARS,GALNT14,ILDR2,LEPR,MAP1B,EBF1,DOCK7,FAT4,L3MBTL4,MPP7,FBN1,UACA,FILIP1,STOM |
| 5.751e-06 | -12.07 | skin-mucosal-malignant_melanoma | COSMIC cancer mutations | skin-mucosal-malignant_melanoma | 2042 | 257 | 17385 | 1698 |
THOC5,ADAL,PPP4R4,ACVR1,SIDT1,GRIK2,ATP8A1,FAM102B,ENAH,CADM2,KIAA1217,DACH2,FAAH2,CHRDL1,ATRNL1,PPP2R2B,SP140,VWA5A,CPE,GLDC,DCDC1,ACVR1C,DCC,NR6A1,ALDH1L2,LRRK2,MSRB3,TNS1,KCND3,GPC6,ENPP1,BMP1,MAPK13,INPP5F,LRFN5,PTPRD,TNFRSF19,DYNC1I1,ADSSL1,SYCP2,ABLIM1,GBGT1,SLC7A11,CNTN4,FLRT3,SLC16A9,ALPK1,MOXD1,COL9A2,CHRM3,IGSF3,SLC37A1,PNP,STAT4,FASN,KIAA1324L,CALCRL,SNAP25,OR11H4,PLCB1,SPATA7,DAGLA,XKR9,TEX15,PLEKHH2,PELI2,EMILIN2,CDH17,AMPD1,ACSM3,ADD2,PKP2,COLEC10,COL14A1,ZFYVE9,TIAM2,ALDH1L1,ZNF365,DNAH5,KCNB2,SCN3A,NPM3,KCNH5,TRAM1L1,ADCY1,NLGN4X,PRKCQ,ATP10D,FGFR1,ZNF711,ARHGAP21,WFS1,INPP4B,PLD5,CTTNBP2,NR3C2,COBL,CCDC148,WDR17,EPS8,NKAIN2,CREB5,COL27A1,AFF2,SMPDL3A,MED12L,FES,B4GALT6,ULBP1,TRPM4,TMC7,VAV3,SYNPO2,LCA5,ARAP2,ATP11A,GUCY1A2,SKAP1,GPLD1,TERT,PLXDC2,PIP5KL1,EXPH5,TRIM2,CACNG3,ACSL1,KIF5A,DNER,IKZF2,HMCN1,FSTL5,F3,EPCAM,EOMES,GRHL1,MARVELD2,ANKFN1,COL19A1,JAKMIP2,PCOLCE2,TMEM132E,TLR4,OR2W3,MYRIP,PTPRE,SLIT2,PDGFRB,SKAP2,ANK2,JPH1,ROR1,SERGEF,EML1,ITGBL1,PIK3C2B,PPARGC1A,MAGI2,APBA2,PRKAA2,FN1,SEC24D,ELOVL7,LAMC3,SETBP1,ZNF215,SORBS3,MLC1,EFEMP1,ZNF354A,LIMCH1,FAR2,NOS3,UNC5C,PODXL2,SLC27A2,SDC3,TEX9,KHDRBS2,SLC46A3,LDHD,AMDHD1,KIAA0355,PTPRN2,OSBPL6,SIX2,SORBS1,ID1,CFH,CELSR3,AKAP5,ARHGAP22,HECW2,OR51B4,SLC7A2,KIF21B,LPIN3,PPP1R9A,COL22A1,SLC22A17,TACC2,EEPD1,PROS1,SCN2A,MET,TMEM67,LRRC8B,PTPRU,TDRD3,TES,NRG3,RNF217,BACH2,GBP1,ITGA2,HGF,SUSD4,LIFR,CTNND2,MAST1,PCDH18,SLC6A9,DYRK3,BMPR2,IL32,GRB14,CLGN,GABRG2,CLSTN2,COL4A5,OVOL2,PPP2R3A,EHD3,STC2,KIAA0319,TFAP2A,SH3PXD2B,IPCEF1,IQGAP3,CES3,DLGAP1,CARD6,MICAL2,CRIM1,MARS,GALNT14,ILDR2,LEPR,MAP1B,EBF1,DOCK7,FAT4,L3MBTL4,MPP7,FBN1,UACA,FILIP1,STOM |
| 5.837e-06 | -12.05 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP | 189 | 39 | 17377 | 1707 |
TCP11L2,RNF144A,C20orf194,PSD3,KCTD12,SLC36A4,ABHD4,KBTBD11,PFN2,SLC19A2,PGAP1,SP8,RAB11FIP5,GALNT1,SEC16B,FRY,CNKSR3,RAP2A,BCL6,ATRNL1,TSPAN13,CKAP4,SMPDL3A,ANTXR2,TUBA1A,TMEM65,STRADB,ATP1B1,MFSD6,CRYBG3,GJC1,TIFA,MYADM,KLF12,PRKCB,MAP2K6,RAB31,B4GALT7,SLC16A10 |
| 5.837e-06 | -12.05 | GSE7764_NKCELL_VS_SPLENOCYTE_UP | MSigDB lists | GSE7764_NKCELL_VS_SPLENOCYTE_UP | 189 | 39 | 17377 | 1707 |
PHACTR3,PLSCR4,RUNX2,BMPR2,SEC24D,PLEKHA5,UBASH3B,ELOVL7,UGDH,CHSY1,FAM81A,IL18R1,RAP2A,GAN,DAB2IP,TMEM37,RAB27B,PTPRE,SPRY2,NTNG1,GAB2,VEGFC,KLHL4,GPSM1,PREX1,SMARCD3,ATP1B1,MFSD6,DSP,CAMK2N1,SMAD3,KLF12,MPP7,PLOD2,CLDN12,C1orf21,ZBTB20,GEM,RNF157 |
| 5.858e-06 | -12.05 | GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_UP | MSigDB lists | GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_UP | 142 | 32 | 17377 | 1707 |
ZHX3,RHOBTB1,RECK,PLEKHA5,HEBP1,ST6GAL1,PFN2,RAC3,NCS1,HECTD2,CCDC120,TLR3,SLC30A4,ABCA5,ALDH1L1,ZDHHC23,TSPAN12,FKBP14,FMNL2,CAND2,QSOX1,ZDHHC15,AIG1,ATP11A,AMIGO1,MFSD9,PRKCB,PLOD2,GNB4,PCGF2,GRIN2D,TANC2 |
| 5.975e-06 | -12.03 | WENG_POR_TARGETS_GLOBAL_UP | MSigDB lists | WENG_POR_TARGETS_GLOBAL_UP | 20 | 10 | 17377 | 1707 |
CYP51A1,GSTM2,IDI1,HMGCS1,MSMO1,TCEA3,GSTM3,SQLE,SCD,DHCR7 |
| 6.032e-06 | -12.02 | GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | MSigDB lists | GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 724 | 108 | 17377 | 1707 |
EPHA3,DNM3,ID1,RHOD,GPR65,PKP2,ADD2,NPM1,NTRK3,NRXN1,PRKCA,SNX9,TBC1D30,CBLN1,PPP1R9A,TBC1D19,SCIN,PPM1E,UNC13B,PMAIP1,DACT1,HRK,DAB2IP,CTTN,TLR4,HSPA2,SLIT2,SNAI2,TBC1D8,FER,PHLDB2,SSH3,GPM6A,EVL,MYLK3,LRRK2,PREX1,FEZ1,PRKCQ,WNT11,AMIGO1,TBC1D16,BCL11A,SNCA,SMAD3,TRIM9,GSN,PTPRJ,INSIG1,NCKAP1L,WIPF3,PLK2,EIF4EBP1,TNFRSF1A,BBC3,KLF5,ERCC5,TMOD2,OXTR,ATG5,TMEFF2,TPM1,MAGI2,COBL,CHMP4C,MEF2C,ROBO2,TBC1D1,STXBP6,SLK,BIK,EPS8,CLSTN2,ARL2,SORBS3,EPHB1,PFN2,RPL13A,SPIRE1,FHOD3,LRRN1,FLRT3,PRKCD,GTF2F2,SGK1,SMAD6,STXBP1,FES,EPB41L5,PAK1,BDNF,RHOQ,SLITRK2,MYO10,RAPGEF2,ASAP3,SLITRK5,TLR6,BAIAP2,TBC1D2,DKK1,MYADM,MPP7,PMEPA1,CDH17,PLD1,CDH2,FNBP1L |
| 6.080e-06 | -12.01 | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | 98 | 25 | 17377 | 1707 |
MXI1,SLC3A2,GARS,ATF4,PDK1,PNP,NR4A1,LDLR,MARS,ATF3,PRDM1,F12,CANX,BMP6,FKBP11,TXNDC5,ISG20,CYP51A1,MYC,PAM,TUFT1,P4HA1,TNFRSF17,AMPD1,DDIT3 |
| 6.084e-06 | -12.01 | regulation of intracellular signal transduction | biological process | GO:1902531 | 1929 | 241 | 17256 | 1658 |
ARHGAP26,DUSP8,GRIK2,LMCD1,GATA3,NDRG2,FAM13A,PRKCA,RAC3,STK24,NOS1AP,F3,GSDME,ARHGEF10L,SIPA1L2,TGFBR3,PMAIP1,AKAP7,RAP2A,EPHB6,RCAN3,TLR4,ENO1,SLIT2,RASGRP1,PDGFRB,CYP1B1,SESN2,GCNT2,ATF4,WLS,TGFA,JPH1,LRRK2,DEPTOR,ROR1,FGF17,PLEKHA1,SESN1,ARHGEF26,GNAI1,INHBC,GPRC5B,HPSE,SH3RF1,RASGRF2,PLK2,ERN1,ADRB1,TNFRSF1A,ARHGAP28,INPP5F,DIRAS1,SPRY4,NRP1,UNC5B,MAGI2,RRAGD,PRKAA2,TYRO3,FN1,RHOBTB1,OPHN1,SORBS3,TNFRSF10C,TNFRSF19,CHD5,IL18R1,MYORG,MECOM,DDIT4,CHN1,RALGPS2,IGF1R,PIK3AP1,MYC,PDE10A,FLRT3,C1QL4,SRGAP1,INAVA,FBXL2,ZNF385A,RNF152,HMGCR,PAK1,FGFR4,RPL26,MID2,RHOQ,MSTN,SPATA13,DUSP9,WWC1,OBSCN,HIP1,PDE8A,PEX5L,TAF4B,PLCB1,HERPUD1,MAPKAPK2,RIPOR2,PELI2,CSF1,SH3BP4,INHBE,IQSEC2,CDH2,SEMA3A,EPHA3,PRKN,BTC,ID1,NEK10,AVPI1,RASAL2,AKAP5,RHOD,IL15,GPR65,ARHGAP22,CHUK,NTRK3,PIBF1,DDR1,TIAM2,TLR3,CNKSR3,DACT1,MAGEA3,BCL6,DAB2IP,PDE4D,WWC2,MET,SNAI2,CTH,IGFBP3,FZD4,NOP53,PTPN6,PREX1,RNF125,ATF3,WNT11,GSTO1,SYNJ2BP,CD40,MAGI3,FGFR1,CAMK2N1,IRS2,ARHGAP21,CXCL10,PTPRJ,PRKCB,GBP1,APELA,WFS1,PLEKHG1,MAP3K21,DUSP19,TNFSF15,HGF,MAPK10,MID1,ARFGEF3,TENM1,TNIK,FARP1,DYRK3,NECAB2,EDA2R,C1QTNF3,PAK5,ARHGEF11,FZD8,REL,EPS8,NLRP14,PSD3,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,BMP6,NEDD4,ARHGAP44,SYDE2,CHN2,MCF2L,PRKCD,RASD2,GHR,RALGAPA2,YBX3,ERRFI1,IQGAP3,TNFRSF11A,SYK,SPRY2,PARP9,DUSP1,VAV3,ARAP2,ARHGEF28,GSTM2,MSX1,PTPN13,RAPGEF2,MCF2L2,CYTH3,LITAF,ASAP3,RASA3,AGAP2,GAREM1,ARHGAP32,RACK1,TLR6,DKK1,GPR37,TRIB3,FGR,MYADM,EDA,NACC2,MAP2K6,AKT3,XBP1,UACA,BMP4,LRRK1,MAP3K20,DDIT3,ATP2B4,BTRC,TPT1 |
| 6.115e-06 | -12.00 | MENSE_HYPOXIA_UP | MSigDB lists | MENSE_HYPOXIA_UP | 92 | 24 | 17377 | 1707 |
PFKFB4,MXI1,PDK1,ENO2,TMEM65,BNIP3L,ATF3,SCD,FAM13A,SERGEF,FAM162A,CEBPB,INSIG1,PLOD2,P4HA2,ALDOC,STC2,STARD4,HK2,P4HA1,BNIP3,CTTN,TC2N,CEBPD |
| 6.194e-06 | -11.99 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | 357 | 62 | 17377 | 1707 |
RGS16,LATS2,DNM3,LGR4,CYP2J2,FBXO4,LDLR,IL13RA1,FAM117B,IGF2BP2,SLC12A6,SFXN3,PRKCA,CA8,TPD52L1,FAM110B,TTC30B,PPP2R3A,FAM131B,MTUS1,RASSF8,CHN1,ZNF362,PMAIP1,DSG2,STC2,SMTN,CTTN,MET,TBC1D9,SYK,PDLIM7,VEGFC,PHLDB2,RAB3B,CD55,PXN,MYO10,SPOCD1,TGFA,C3orf52,TMTC4,PREX1,BATF,MBNL2,LEPR,STEAP1,CENPV,HOMER3,ISG20,PMEPA1,SH3RF1,PLOD2,P4HA2,XBP1,WWTR1,HK2,MBOAT2,PTGES,SMYD3,PKIA,CTNND2 |
| 6.218e-06 | -11.99 | GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_UP | MSigDB lists | GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_UP | 169 | 36 | 17377 | 1707 |
NMNAT3,ST6GAL1,GTF2IRD1,SELL,GRK6,SATB1,IKZF2,SEMA6A,ABLIM1,TGFBR3,RALGPS2,DACT1,ADCY6,TSPAN13,TOX,ST8SIA1,PACSIN1,RRAS2,RASGRP1,PDK1,COL4A4,CYTH3,RAPGEF4,CALCRL,NPC2,LRAT,ZIC1,IRS2,ID3,PMEPA1,RGS10,ARHGAP28,SIX2,MME,AMPD1,ABCG1 |
| 6.225e-06 | -11.99 | positive regulation of cell communication | biological process | GO:0010647 | 1745 | 221 | 17256 | 1658 |
CACNG3,ACVR1,LGR4,TRIM16,GRIK2,SYT12,VAMP8,LMCD1,GATA3,CTBP2,ABAT,PRKCA,STK24,NOS1AP,SKI,F3,GSDME,TGFBR3,PMAIP1,ITGB3,HRK,EPHB6,MYRIP,TLR4,RASGRP1,PDGFRB,CYP1B1,GCNT2,ATF4,SKAP2,WLS,TGFA,LRRK2,YAP1,ACVR2B,ROR1,FGF17,INHBC,GSN,GPRC5B,HPSE,CCBE1,PLK2,ERN1,ADRB1,TNFRSF1A,BBC3,TMOD2,DIRAS1,OXTR,NRP1,UNC5B,MLLT3,RRAGD,TYRO3,SORBS3,CHSY1,TNFRSF10C,SLC1A3,TNFRSF19,CHD5,IL18R1,MYORG,CHN1,CA2,IGF1R,PIK3AP1,LRP6,INAVA,BNIP3,STXBP1,ZNF385A,RIMS2,HMGCR,PAK1,FGFR4,RPL26,MID2,BDNF,ATP5IF1,DISC1,MSTN,SH2D2A,DUSP9,WWC1,HIP1,PDE8A,SNAP25,PLCB1,FAM162A,BAIAP2,MAPKAPK2,ADAMTS3,PELI2,CSF1,MPP2,INHBE,CDH2,SEMA3A,SFN,EPHA3,PRKN,BTC,SORBS1,NEK10,AVPI1,IL15,GPR65,CHUK,NTRK3,NRXN1,PIBF1,DDR1,TLR3,UNC13B,KMO,DACT1,SHF,ACVR2A,DAB2IP,MET,GLI1,CTH,IGFBP3,INTU,FZD4,PFKFB2,PTPN6,SHANK2,WNT11,GSTO1,ATF3,CD40,FGFR1,SNCA,IRS2,SMAD3,CXCL10,PTPRJ,PRKCB,APELA,ITGA2,MAP3K21,DUSP19,TNFSF15,HGF,GRB10,BMPR1A,DISP1,MAPK10,MID1,TENM1,TNIK,NECAB2,EDA2R,C1QTNF3,BMPR2,GRB14,FZD8,REL,EPS8,BIK,CLSTN2,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,TSPAN17,BMP6,NEDD4,MCU,NEO1,NKX6-1,CHN2,PRKCD,RASD2,GHR,AFAP1L2,DYNC2H1,PCK2,IQGAP3,GFI1,TNFRSF11A,TESPA1,SYK,SPRY2,PARP9,TRPM4,VAV3,SH3BP2,GSTM2,RAB3B,MSX1,RAPGEF2,SYBU,LITAF,GAREM1,RACK1,SKAP1,TLR6,GPLD1,DKK1,GPR37,PTPRC,FGR,EDA,NACC2,TERT,MPP7,MAP2K6,AKT3,XBP1,GRIN2D,LRRK1,BMP4,SHOX2,MAP3K20,DDIT3,FOXA1 |
| 6.262e-06 | -11.98 | adherens junction | cellular component | GO:0005912 | 532 | 82 | 18223 | 1724 |
ARHGAP26,SORBS1,ARHGAP22,PKP2,NPM1,ENAH,CADM2,TNKS1BP1,CTNNA2,PPFIBP1,ITGB3,LIN7A,POF1B,MARCKS,CTTN,TLN2,PDGFRB,FZD1,RPS13,PHLDB2,TNK2,EVL,TES,CAPN5,VIM,TNS1,TMEM47,DSP,GSN,LMLN,GYPC,PTK7,ITGA2,OXTR,SPRY4,NRP1,CTNND2,FRMD5,LPP,EFNB2,MRC2,BMPR2,STXBP6,ITGA6,ARL2,SORBS3,TJP1,RPL13A,FLRT3,RPS11,EHD3,SCARF2,TSPAN9,RRAS2,FES,PDLIM7,PAK1,EPB41L5,CDH26,SYNPO2,PXN,PARD3B,CYTH3,ASAP3,FHL2,FERMT2,PALLD,SNTB1,PEAK1,BAIAP2,PTPRC,RPL12,DOCK7,RND3,MPP7,FAT1,SVIL,RPL4,CDH2,NPHP1,CSRP2,MME |
| 6.323e-06 | -11.97 | FN3_dom | interpro domains | IPR003961 | 204 | 41 | 18492 | 1811 |
EPHA3,TYRO3,FN1,ROBO2,PTPRD,IL13RA1,EPHB1,COL14A1,F3,NEO1,FSD1,SPEG,CNTN4,LRRN1,IGF1R,ABI3BP,FLRT3,ANKFN1,GHR,KIAA0319,EPHB6,NCAM1,FANK1,MID2,PTPRU,DCC,ATF7IP2,OBSCN,SDK1,FNDC3A,LEPR,TRIM9,PTPRC,PTPRJ,NCAM2,PTPRS,MYOM2,IL9R,LIFR,MID1,CNTN1 |
| 6.360e-06 | -11.97 | GO_HEART_DEVELOPMENT | MSigDB lists | GO_HEART_DEVELOPMENT | 450 | 74 | 17377 | 1707 |
ACVR1,ID1,GATA3,PKP2,ADAMTS6,NTRK3,TRPS1,TGFBR3,RPS6KA2,SETDB2,KCNAB1,EOMES,MARCKS,DNAH5,CPE,PDGFRB,SNAI2,FZD1,MYLK3,TMEM65,ANK2,FGF12,YAP1,WNT11,CBY1,ACVR2B,SAV1,DSP,GJC1,SMAD3,ARMC4,PDLIM3,PTK7,PAM,SEMA3C,OXTR,BMPR1A,ATG5,TPM1,NRP1,MEF2C,PCSK5,HEY1,SCN5A,BVES,OVOL2,NEDD4,FHOD3,HOPX,GATA2,FLRT3,DSG2,LRP6,DYNC2H1,SH3PXD2B,SMAD6,MICAL2,MSX1,VLDLR,DCHS1,FHL2,PRICKLE1,CALCRL,RYR2,SMARCD3,PRDM1,ZFPM2,HEG1,ID3,FAT4,FBN1,HEYL,BMP4,SHOX2 |
| 6.417e-06 | -11.96 | GO_CELL_CELL_JUNCTION | MSigDB lists | GO_CELL_CELL_JUNCTION | 365 | 63 | 17377 | 1707 |
CGN,SCN5A,AMOTL1,SORBS1,FGF13,BVES,PKP2,TJP1,CADM2,LCP2,MLC1,CTNNA2,CD53,EPCAM,EPB41L3,SCN1B,KAZN,FLRT3,MARVELD2,DSG2,PRKCD,POF1B,LIN7A,MPDZ,IQGAP3,SCN2A,TLN2,JAM2,PERP,FGFR4,DBN1,PAK1,PTPRU,TMEM65,FZD4,ANK2,PTPN6,GJB2,RAPGEF2,PARD3B,ABCC2,TMEM47,CDC42BPA,ATP1B1,SKAP1,DSP,STEAP1,JAM3,MAGI3,GJC1,HEG1,PTPRJ,MYADM,MPP7,PTK7,FAT1,CLDN12,ATP7B,OXTR,MAGI2,CDH2,NPHP1,OCLN |
| 6.516e-06 | -11.94 | SH3 | prosite domains | PS50002 | 223 | 46 | 12060 | 1278 |
ARHGAP26,SORBS1,DOCK1,RUSC2,UBASH3B,EPS8,SORBS3,TJP1,DOCK3,CACNB4,SNX9,DOCK2,CACNB2,MCF2L,ZDHHC6,SRGAP1,CTTN,SH3PXD2B,PACSIN1,NEB,TNK2,VAV3,SKAP2,MPP1,SHANK2,SPATA13,PACSIN3,OBSCN,ARHGAP32,DOCK5,SKAP1,DSP,FRK,BAIAP2,ARHGEF26,FGR,SH3GL2,MPP7,SH3RF1,ABI3,SH3BP4,MPP2,MAP3K21,DLG2,FNBP1L,NPHP1 |
| 6.541e-06 | -11.94 | adenocarcinoma | COSMIC cancer mutations | adenocarcinoma | 17219 | 1696 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,ZBBX,SNAP25,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,ATOX1,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,C9orf116,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,PURG,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,FBXO4,STXBP6,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,SLX1B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,GFRA1,FMNL2,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,SMARCD3,CALCRL,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,EOMES,KCNN2,KCNAB1,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,CHSY3,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PDZD7,PIK3AP1,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTC30A,TTYH2,CCDC85A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,FAM27C,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM |
| 6.556e-06 | -11.94 | GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP | 183 | 38 | 17377 | 1707 |
SERINC5,MXI1,TCP11L2,SIDT1,LPCAT2,HEBP1,TNFAIP8L2,FHDC1,SELL,DOCK2,PGAP1,FBXO32,CA2,SEMA4F,EEF2,ITGB3,TMEM86A,TSPAN13,DENND1C,PTPRE,ZFP36L2,SMPDL3A,RHOQ,SPATA6,LRRK2,BNIP3L,MAFB,MSRB3,RASA3,WNT11,PTPRC,HPSE,GNB4,AKT3,ABI3,INPP5F,IL9R,TPT1 |
| 6.611e-06 | -11.93 | SMID_BREAST_CANCER_LUMINAL_B_UP | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_B_UP | 156 | 34 | 17377 | 1707 |
CELSR1,CELSR3,CLSTN2,GATA3,KIF5C,ISYNA1,ABAT,NOVA1,PCLO,SLC19A2,TBC1D30,NELL2,CHN2,FLRT3,RAB26,SREBF1,GSTM3,TBC1D9,AGL,MYT1,GFRA1,PCSK6,B9D1,EVL,SLC27A2,SYBU,C9orf116,TRIM9,ENPP1,KCNK15,SERPINI1,MAGI2,PTGES,FOXA1 |
| 6.648e-06 | -11.92 | primary_central_nervous_system_lymphoma | COSMIC cancer mutations | primary_central_nervous_system_lymphoma | 713 | 106 | 17385 | 1698 |
EXPH5,EPHA3,GXYLT2,AMOTL1,PPP4R4,GRIK2,CNTNAP3,FHDC1,MSR1,PLXNA2,CTBP2,NRXN1,TBC1D30,AARS,DACH2,HMCN1,SLC9A7,ZSCAN5A,PLS3,SPEG,GPRIN1,PPFIA2,BCL6,ATRNL1,ACVR2A,NAP1L3,SLC2A12,POU2F2,DNAH5,TLR4,NEB,NKX2-1,MYLK3,DCC,WLS,YAP1,NLGN4X,SGK2,BATF,GPC6,ARHGEF26,NRG3,NCKAP1L,MAP2,ITGA2,TNFRSF1A,NCOA7,ARHGAP28,SOHLH2,ZBTB20,UNC5B,NEUROG2,SPOCK3,PURG,SV2B,ANKRD13B,STXBP5L,FN1,ST6GAL1,SETBP1,CBS,FAM117B,SLC12A6,FRAS1,PRKCD,LRP6,MPDZ,TOX,KLF9,ERRFI1,VGLL4,PRR16,SLC45A3,MED12L,B4GALT6,PNMA2,IGSF3,TRPM4,IL17RD,RAX,PCDH10,ANKRD20A2,USP2,LRRIQ1,PARD3B,PTPN13,DCHS1,RYR2,SLITRK5,OBSCN,ATP11A,PRDM1,GPLD1,EBF1,CD37,PLPPR2,THBS4,MYOM2,HK1,CDH2,TBC1D4,TRPC3,MMP16,MME,CACNA2D1,ABCG1 |
| 6.648e-06 | -11.92 | haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-primary_central_nervous_system_lymphoma | 713 | 106 | 17385 | 1698 |
EXPH5,EPHA3,GXYLT2,AMOTL1,PPP4R4,GRIK2,CNTNAP3,FHDC1,MSR1,PLXNA2,CTBP2,NRXN1,TBC1D30,AARS,DACH2,HMCN1,SLC9A7,ZSCAN5A,PLS3,SPEG,GPRIN1,PPFIA2,BCL6,ATRNL1,ACVR2A,NAP1L3,SLC2A12,POU2F2,DNAH5,TLR4,NEB,NKX2-1,MYLK3,DCC,WLS,YAP1,NLGN4X,SGK2,BATF,GPC6,ARHGEF26,NRG3,NCKAP1L,MAP2,ITGA2,TNFRSF1A,NCOA7,ARHGAP28,SOHLH2,ZBTB20,UNC5B,NEUROG2,SPOCK3,PURG,SV2B,ANKRD13B,STXBP5L,FN1,ST6GAL1,SETBP1,CBS,FAM117B,SLC12A6,FRAS1,PRKCD,LRP6,MPDZ,TOX,KLF9,ERRFI1,VGLL4,PRR16,SLC45A3,MED12L,B4GALT6,PNMA2,IGSF3,TRPM4,IL17RD,RAX,PCDH10,ANKRD20A2,USP2,LRRIQ1,PARD3B,PTPN13,DCHS1,RYR2,SLITRK5,OBSCN,ATP11A,PRDM1,GPLD1,EBF1,CD37,PLPPR2,THBS4,MYOM2,HK1,CDH2,TBC1D4,TRPC3,MMP16,MME,CACNA2D1,ABCG1 |
| 6.661e-06 | -11.92 | GSE7852_TREG_VS_TCONV_THYMUS_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_THYMUS_UP | 190 | 39 | 17377 | 1707 |
CREB3L2,TTC39B,LGALS3,KIF5C,NRN1,IKZF2,IL18R1,PPP2R3A,GPR15,IGF1R,EOMES,ALDOC,TSPAN13,KLF9,PROS1,MED7,IGSF3,DUSP1,PNP,CRIM1,PTPN13,WLS,TMEM126A,GSTO1,PRDM1,ARRDC4,TTC28,PEAK1,FAM162A,MKX,GABARAPL1,MYADM,PLAGL1,PMEPA1,PTPRS,SH3BGRL2,GEM,NRP1,CSRP2 |
| 6.787e-06 | -11.90 | non_seminoma | COSMIC cancer mutations | non_seminoma | 493 | 79 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,ERGIC1,MARK1,PDK1,ACVR1C,ALDH1L2,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,SEC24D,UBAC2,PKN1,EPHB1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,NOS3,PAK1,FGFR4,PCDH10,DCHS1,NUAK2,OBSCN,STRADB,CDC42BPA,MAPKAPK2,TRIB3,FGR,TMEM237,PKN3,AKT3,MAP2K6,OSBPL5,NEK11,FILIP1,LARP1,CACNA2D1 |
| 6.858e-06 | -11.89 | ONDER_CDH1_TARGETS_1_UP | MSigDB lists | ONDER_CDH1_TARGETS_1_UP | 130 | 30 | 17377 | 1707 |
CD55,ZNF516,PNRC1,PRSS16,IL15,SEC24D,THSD4,CRIP2,ATF3,CHAC1,PRKCA,PHGDH,ABHD4,LEPR,GABARAPL1,ASNS,PPFIBP1,LHX6,STC2,CCNA1,BCL6,KLF9,DBP,CTTN,PCK2,IL1RAP,CSRP2,CTH,ABCG1,CYP1B1 |
| 6.901e-06 | -11.88 | desmosome organization | biological process | GO:0002934 | 10 | 7 | 17256 | 1658 |
PKP2,PRKCA,GRHL1,DSP,PERP,DSG2,SNAI2 |
| 6.931e-06 | -11.88 | cell part | cellular component | GO:0044464 | 16492 | 1609 | 18223 | 1724 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,SMIM20,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,ZNF788P,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,SELENOM,LAPTM4B,HOXD13,CDH2,GVINP1,SHTN1,DOCK9,MTG1,TFCP2L1,SCAMP1,SUGCT,ABHD13,ADD2,MAPK4,GRK6,SLC19A2,PLPP1,TLR3,MAGEA3,ALDH1L1,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,LRRC27,RAB30,CGB2,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,PDLIM7,TRPM4,B9D1,VEGFC,LZTS3,OPLAH,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,PHC1,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,SEC16B,AADAT,ITGB3,TBC1D32,TMEM143,JAKMIP2,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,CR2,SESN1,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,ADGRA3,NEUROG2,TC2N,CACUL1,RRAGD,LONRF1,TYRO3,KCNV1,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,B3GLCT,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,MYH15,SNAI2,IGFBP3,RPS13,INTU,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,KIZ,BMPR2,KLHL13,PAK5,MCTP2,RASD1,PRDM8,USP30,FOXP2,TTC1,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,SYK,ATP2B1,PCSK6,CES3,DUSP1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,PALD1,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,SLC9C1,WISP3,KLHL3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SEMA6B,LRFN5,KLF8,MRC2,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,LRRC49,HERC6,APBA1,TNFRSF19,GAS1,MTUS1,ABLIM1,RALGPS2,SLC7A11,NOVA2,MYC,SCARF2,PRKG1,SREBF1,GRIP1,MAST4,FAM155A,COL9A2,GPR161,BOD1,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,WDR19,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ERG28,ASNS,ZNF438,POU5F1B,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,TRIQK,ATP10D,SNCA,ISG20,PATJ,ZNF711,IKZF3,POPDC3,BEX3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ADGRB2,GSAP,LRRC55,IRX5,AFF2,GPR155,RMDN2,DYNC2H1,CERS4,ERRFI1,TBC1D9,SMAD6,B4GALT6,SLC40A1,VAV3,ALDH2,ARHGEF28,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,HOXA1,ZFP62,TERT,MCC,SVIL,LRRK1,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,SLC2A13,HMCN1,CHST10,F3,GSDME,ADPRHL1,EPCAM,PPM1E,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,CEMIP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,TMEM150B,GPRC5B,HPSE,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,SCD,CHSY1,SPINK5,PCDHB14,ZNF354A,EEF2,SLC30A4,INAVA,VSIR,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,ATP5IF1,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,CATSPERE,STEAP1,HERPUD1,RIPOR2,PLAGL1,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,SLX1B,OVOL2,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,IPCEF1,TESPA1,RBMS2,PNMA2,USP2,KDM5B,HNF4G,CRIM1,SYBU,CCDC184,ASAP3,PEAK1,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,RND3,ACER2,CTSV,SLC18B1,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,PPP1R26,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,ZBED9,NKX2-1,CFAP44,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,HACD1,MSRB3,F12,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,SLK,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,ENAM,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,OR11H4,TAF4B,MBNL2,CPEB1,DHX32,BEX4,SH3GL2,CDH17,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,CHRNA5,GPRIN1,KMO,EEF1AKMT2,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,PERP,SSH3,GARS,FZD4,NPM3,KCNH5,NKX3-2,ATF7IP2,PXYLP1,RAB38,TTC28,METAP1D,FGFR1,IRS2,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,EDA2R,ROBO2,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,LCA5,CLYBL,RAPGEF2,ELOVL3,GAREM1,RACK1,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,ASS1,HDGFL3,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FKBP9,KCNN2,KCNAB1,TCAF2,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLPP2,PLEKHA1,BATF,TCERG1L,PLEKHB1,TSKU,MAP2,P4HA2,GNB4,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,SETBP1,MLC1,IL18R1,PGAP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,SPATA13,PPFIA4,PDE8A,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,PRKN,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CTNNA2,CYP26A1,FAM131B,RIDA,SLC22A17,ZDHHC6,LHX6,MYO3B,ADGRL1,CLVS2,SCN2A,ZNF488,GLI1,CTH,TMEM67,EVA1A,EVL,TUBA1A,UROS,NOP53,FGF12,GSTO1,RARRES2,FRK,ETNPPL,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,ZNF701,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,KLF9,SH3PXD2B,PCK2,ESD,SLC45A3,DLGAP1,MOB1B,MICAL2,PPP1R3D,NUGGC,LITAF,NUAK2,FNDC3A,NPDC1,MKX,MAP10,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,DLG2,RPL4,SLC22A15,PAX9,MYRF,TBC1D4,FILIP1,MYCBP2,CGN,ACVR1,PPP4R4,LANCL3,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,RAC3,AARS,STK24,NCS1,MOK,SLC22A18,SLC16A2,CHRDL1,GSTM3,SP140,RCAN3,VWA5A,PACSIN1,TBC1D8,EML6,DCDC1,NR6A1,ALDH1L2,KLHL4,DNAJC6,DEPTOR,DESI1,MEF2B,AGO4,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,CCDC181,ENTPD7,RASGRF2,B3GALT2,SPART,UNC5B,ZBED8,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,MYORG,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,PDZD7,PIK3AP1,MSMO1,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,TTYH2,COLGALT2,TTC30A,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,VPS37D,PKN3,PMEPA1,IQSEC2,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,ZNF827,TMEM53,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,MAPK10,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CLBA1,CCNJL,ARL2,GABRR2,RGS7,SELENOP,GDPD5,SLC35G2,NEDD4,HOPX,KDM7A,RGS17,SOAT2,MGAT1,SGK3,PRKG2,RALGAPA2,SLC6A15,PHYKPL,FIG4,YBX3,GFI1,SEPT3,SPRY2,PFKFB4,ARAP2,SYNPO2,HYKK,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZNF714,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,PCGF2,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ABAT,DNER,RBM11,CACNB4,IKZF2,ABHD4,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,TUBB4A,CYP51A1,ARHGEF10L,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,EPHB6,PTPRE,FANK1,GALNT18,OR2W3,SLIT2,PRKACB,RASGRP1,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,GRK3,SERGEF,EML1,AK1,ITGBL1,NCAM2,C8orf88,NCOA7,APBA2,SLC9B1,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,ADGRG6,DDIT4,CA2,RPS11,EBF4,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,GALNT17,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,ADGRB3,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,LACC1,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,FAAP20,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,ZFPM2,MAP1B,RERE,GPR37,TIFA,MYADM,MPP7,NACC2,GCSAM,PRCP,MAP2K6,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 7.017e-06 | -11.87 | GO_BIOLOGICAL_ADHESION | MSigDB lists | GO_BIOLOGICAL_ADHESION | 988 | 139 | 17377 | 1707 |
MPZL3,CNTNAP3,GATA3,LILRB1,STAT5B,CADM2,PRKCA,BCAN,CHST10,EPDR1,PCDH7,EPCAM,EOMES,PPFIA2,ITGB3,COL19A1,CTTN,TLN2,CYP1B1,ITGB7,COL4A3,WISP3,FEZ1,TMEM47,BATF,HPSE,NCAM2,ITGBL1,TNFSF4,LPP,TYRO3,EFNB2,BCL11B,INPPL1,RUNX2,CELSR1,FN1,BVES,PTPRD,ITGA6,LAMC3,SORBS3,APBA1,CD7,SATB1,IL18R1,PCDHB14,CNTN4,SLC7A11,FLRT3,SCARF2,LRP6,MPDZ,NCAM1,STXBP1,JAM2,EPB41L5,PCDH10,CDH26,PODXL2,DCHS1,SDC3,MAFB,SDK1,NEGR1,FAT1,THBS4,EMILIN2,CDH17,EGFL7,CDH2,EPHA3,ID1,SORBS1,IL15,CELSR3,RHOD,COL18A1,PKP2,NRXN1,RADIL,COL14A1,DDR1,DOCK2,CBLN1,CTNNA2,PPFIBP1,MARCKS,DOCK8,PERP,FER,COL6A2,FZD4,PTPRU,PTPN6,PREX1,NLGN4X,ATP1B1,AMIGO1,DSP,JAM3,ENTPD1,SMAD3,LMLN,PTK7,ITGA2,LAMB1,PTPRS,ATG5,CTNND2,CNTN1,PCDH18,ROBO2,IL32,FZD8,CD276,CLSTN2,SELL,GAS6,EPHB1,NEDD4,NEO1,SCN1B,DSG2,SMAD6,ZFP36L2,SYK,PXN,FERMT2,FNDC3A,PEAK1,LEPR,CEBPB,PTPRC,PCDHB7,FAT4,RND3,CLDN12,NPHP1 |
| 7.155e-06 | -11.85 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_DN | 170 | 36 | 17377 | 1707 |
MYO1D,FARP1,PPP4R4,SORBS1,SEC24D,LPCAT2,MLF1,YPEL2,NIPSNAP3B,MCU,EPCAM,GALNT1,HMGCS1,PMAIP1,AKAP7,PCBP4,MARVELD2,CERS4,GFI1,RASGRP1,HMGCR,TRPM4,TMEM43,PTPN13,ATF3,BATF,DOCK5,HERPUD1,DHX32,IRS2,CEBPB,HPSE,GNB4,RAI14,ATP2B4,CSRP2 |
| 7.278e-06 | -11.83 | GO_DENDRITE | MSigDB lists | GO_DENDRITE | 436 | 72 | 17377 | 1707 |
DNM3,FGF13,PRSS12,GRIK2,AKAP5,CANX,BCAN,DNER,PPP1R9A,NCS1,NELL2,KCNN2,KCNAB1,CHRNA5,DAB2IP,MARCKS,CTTN,KCNB2,DBN1,GPM6A,KCNIP3,WLS,SHANK2,LRRK2,PREX1,NLGN4X,FEZ1,PRKAR2B,AMIGO1,KCND3,TTLL7,GABARAPL1,CAMK2N1,TRIM9,WFS1,PLK2,BMPR1A,PPARGC1A,MAGI2,CTTNBP2,COBL,LZTS1,CTNND2,MYO1D,FARP1,BMPR2,LRP4,APBB1,OPHN1,P2RY1,SLC1A3,EPHB1,ARHGAP44,KCNJ4,GRIP1,BNIP3,MPDZ,CHRM3,ZNF385A,PAK1,DPYSL5,HOMER2,ARHGAP32,BAIAP2,CPEB1,MAP1B,ICA1,RPL28,GNAO1,SEMA3A,MME,ATP1A3 |
| 7.391e-06 | -11.82 | GO_MOLECULAR_FUNCTION_REGULATOR | MSigDB lists | GO_MOLECULAR_FUNCTION_REGULATOR | 1284 | 173 | 17377 | 1707 |
ARHGAP26,PHACTR3,PPP4R4,CACNG3,FGF13,RECK,DNAJC3,VAMP8,NPM1,DOCK3,FAM13A,SKI,ARHGEF10L,ADPRHL1,BAG3,SIPA1L2,PPP1R26,KCNAB1,KCNS3,PCOLCE2,PPP2R2B,RCAN3,RAPGEF5,SLIT2,RASGRP1,PDGFRB,TBC1D8,TNK2,KCNIP3,COL4A3,LRRK2,ELMOD1,PRKAR2B,FGF17,SGK2,SERGEF,ARHGEF26,KCNMB4,GPRC5B,NCKAP1L,RASGRF2,ADRB1,ARHGAP28,SERPINI1,SPOCK3,KCNV1,RGS16,ALOX5AP,STXBP5L,FN1,TBC1D1,OPHN1,GPSM2,PFN2,SPINK5,HPCAL4,GRPEL2,CHN1,RALGPS2,FRY,CACNB2,FLRT3,SRGAP1,PRKG1,LRP6,NCAM1,DENND1C,GFRA1,FGFR4,TBC1D8B,RAPGEF4,GPSM1,PACSIN3,SPATA13,OBSCN,PLCB1,TBC1D2,MMP15,SH3BP4,IQSEC2,FNBP1L,TESC,SFN,DOCK9,BTC,PCSK1N,RASAL2,DOCK1,C4A,ARHGAP22,RGS20,PKP2,NRXN1,DENND3,DOCK2,TBC1D30,TIAM2,TBC1D19,DAB2IP,PROS1,SERPINH1,DOCK8,IGFBP3,DPP10,CSN2,FGF12,PREX1,WNT11,AMIGO1,ATP1B1,DOCK5,TBC1D16,FGFR1,SNCA,IRS2,CAMK2N1,CXCL10,ARHGAP21,NRG3,PRKCB,PLEKHG1,RGS10,DUSP19,DENND5B,FARP1,ARHGEF11,IPO5,PSD3,ARL2,GAS6,RGS7,PPP2R3A,ARHGAP44,NEDD4,SYDE2,RGS17,CHN2,SCN1B,MCF2L,PRKCD,SGK3,KCNMB3,RALGAPA2,SGK1,AFAP1L2,TSPAN13,IQGAP3,ERRFI1,TBC1D9,SPRY2,MOB1B,VAV3,RIN2,ARAP2,CRIM1,MCF2L2,RAPGEF2,CYTH3,ASAP3,RASA3,PHACTR2,AGAP2,ARHGAP32,GPLD1,DKK1,TRIB3,DOCK7,GRIN2D,TBC1D4,DOCK6,MMP16,PKIA,ATP2B4 |
| 7.493e-06 | -11.80 | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_UP | MSigDB lists | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_UP | 184 | 38 | 17377 | 1707 |
BMPR2,ESRP1,KIF5C,NDRG2,RNF24,SCD,WDFY4,CBLN1,NUMBL,KCNAB1,WWC2,PACSIN1,SCN2A,NIPAL2,MET,FKBP14,SEMA6C,NKX2-1,MICAL2,GCNT2,ACVR1C,FOXN3,FGF12,CTTNBP2NL,CD40,JAM3,TRIM9,FGR,VPS37D,PMEPA1,CCNA1,PGM2L1,SLCO5A1,SH3BGRL2,TNFRSF17,TBC1D4,DOCK6,OSBPL6 |
| 7.513e-06 | -11.80 | GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 413 | 69 | 17377 | 1707 |
EPHA3,NBL1,AKAP5,NTRK3,NRXN1,CBLN1,PPP1R9A,SEMA6A,RND2,BCL6,DAB2IP,MARCKS,PACSIN1,ZNF488,SLIT2,GLI1,FEZ1,ATOH1,AMIGO1,FGFR1,BCL11A,GPRC5B,PTK7,HGF,OXTR,NRP1,MAGI2,COBL,CNTN1,MEF2C,WASF3,FN1,BMPR2,ROBO2,PTPRD,PLAG1,APBB1,CLSTN2,EPHB1,GDPD5,BMP6,NKX6-1,NUMBL,LRRN1,SCN1B,GATA2,FLRT3,SGK1,FIG4,FES,RIMS2,VEGFC,DISC1,BDNF,SLITRK2,RAPGEF2,VLDLR,SLITRK5,SMARCD3,BAIAP2,CPEB1,MAP1B,NEGR1,HEYL,CSF1,BMP4,SEMA3A,SHOX2,FOXA1 |
| 7.590e-06 | -11.79 | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_UP | MSigDB lists | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_UP | 191 | 39 | 17377 | 1707 |
TNIK,BACE1,GTF2IRD1,SELL,RASL11B,NDRG2,IGF2BP2,GABRR2,CD7,BBS9,UBTD2,HECTD2,NEDD4,CA2,RALGPS2,FRY,ITGB3,SGK3,ADCY6,MARCKS,MYO6,PAK1,EIF4E3,FOXN3,BNIP3L,ZNF605,CALCRL,TNS1,ATP1B1,ZDHHC14,MMP15,GSN,IKZF3,BACH2,GPRC5B,PMEPA1,AMPD1,SLC16A10,DDIT3 |
| 7.590e-06 | -11.79 | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP | MSigDB lists | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP | 191 | 39 | 17377 | 1707 |
DMXL2,SCAMP1,UBASH3B,PSTPIP2,ITGA6,EPS8,YPEL2,PRKCA,STK24,MCOLN2,EPCAM,EIF1,VWA5A,TBC1D9,B4GALT6,PARD3B,LITAF,VIM,PDE8A,PRDM1,NPC2,PLEKHA1,BATF,ASPH,MGMT,MYADM,NACC2,SH3RF1,PMEPA1,HK2,RAB31,AHNAK2,CDH17,RCN3,SH3BGRL2,ZBTB20,GEM,LIFR,NR3C2 |
| 7.590e-06 | -11.79 | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_UP | 191 | 39 | 17377 | 1707 |
GNG12,ACSL1,DYRK3,ALOX5AP,GPR65,MORC4,CTBP2,NEDD4,TUBB4A,MARVELD2,TSC22D1,STEAP3,MED7,PTPRE,CKAP4,B4GALT6,PAK1,PNP,TES,MGAT4B,PANK1,DEPTOR,PHACTR2,VIM,CA13,BCL11A,BEX4,MAPKAPK2,SFXN1,TIFA,ICA1,DOCK7,MYADM,OSBPL5,RAB31,RAI14,GRB10,LRRK1,CMPK2 |
| 7.654e-06 | -11.78 | GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_DN | MSigDB lists | GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_DN | 157 | 34 | 17377 | 1707 |
LATS2,MXI1,RASAL2,TSPAN15,CLGN,CTBP2,NUDT12,ZNF354A,KMO,DACT1,JAKMIP2,GULP1,PTPRE,SPRY2,RAPGEF5,ALG10B,AGPAT4,CYTH3,C3orf52,HIP1,TTYH2,ARHGAP32,NPC2,ZNF618,NEGR1,IRS2,GALNT3,ADAMTS3,CLDN12,GNB4,PELI2,RAB30,SLC43A1,ACSM3 |
| 7.729e-06 | -11.77 | Pkinase_C | pfam domains | PF00433 | 29 | 12 | 17054 | 1666 |
RPS6KA2,PRKCB,PKN3,AKT3,PRKCD,SGK3,SGK1,PRKCQ,CDC42BPA,SGK2,PRKCA,PKN1 |
| 7.948e-06 | -11.74 | Pkinase_C | interpro domains | IPR017892 | 29 | 12 | 18492 | 1811 |
RPS6KA2,PRKCB,PKN3,AKT3,PRKCD,SGK3,SGK1,PRKCQ,CDC42BPA,SGK2,PKN1,PRKCA |
| 7.948e-06 | -11.74 | Ricin_B-like_lectins | interpro domains | IPR035992 | 29 | 12 | 18492 | 1811 |
GALNT3,GALNT1,MRC2,DCDC1,GALNT6,GALNT12,CRYBG1,GALNT17,GALNT13,GALNT14,GALNT18,CRYBG3 |
| 7.987e-06 | -11.74 | presynapse | cellular component | GO:0098793 | 373 | 62 | 18223 | 1724 |
DOC2A,DMXL2,SV2B,PRKN,SLC6A9,SCAMP1,GRIK2,PRSS12,SYT12,APBB1,BLVRB,VAMP8,OPHN1,KCTD12,NRXN1,APBA1,KCNC4,PFN2,PCLO,ARHGAP44,UNC13B,PPFIA2,FLRT3,RAB26,ADGRL1,LIN7A,CADPS2,RAB27B,SYNGR3,PACSIN1,SEPT3,STXBP1,CHRM3,RIMS2,SLC40A1,BDNF,KCNIP3,RAB3B,LRRK2,PPFIA4,HIP1,SNAP25,ROR1,RABAC1,BAIAP2,SNCA,TRIM9,GRIK4,ICA1,SH3GL2,FCHO2,ITGA2,RGS10,PTPRS,PTPRN2,SEPT5,APBA2,CTTNBP2,CDH2,STON2,MME,SNPH |
| 8.204e-06 | -11.71 | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | MSigDB lists | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | 779 | 114 | 17377 | 1707 |
CGN,AMOTL1,ID1,RASAL2,CNTNAP3,RHOD,PTPN21,PLXNA2,GATA3,PKP2,COBLL1,ENAH,ADAMTS6,SPATS2L,F3,PLS3,CPNE2,ZNF362,DACT1,STARD4,SERINC2,SCRN1,DAB2IP,MET,ENO1,FANK1,PERP,SNAI2,IGFBP3,PHLDB2,ANTXR2,CD55,PTPRU,PFKFB2,DSTN,TES,TGFA,C3orf52,NFE2L1,YAP1,VIM,SLC25A28,ATF3,COTL1,PLEKHA1,RAB38,SAV1,DOCK5,DSP,TSKU,GABARAPL1,SMAD3,SLC7A1,ARHGAP21,ITGBL1,SH3RF1,ITGA2,WWTR1,TNFRSF1A,PTPRS,PIK3C2B,MBOAT2,STON2,KCTD1,GNG12,LGALS3,BMPR2,ITPRIP,TSPAN15,GTF2IRD1,SETBP1,SCD,TJP1,SLC1A3,PHLDA2,PRRG4,NEDD4,ABLIM1,ABCA5,MYC,DSG2,FAM107B,SREBF1,TFAP2A,TSC22D1,AFAP1L2,NCEH1,SMAD6,MAST4,SYK,SNX7,FADS1,RIN2,PNP,MYO10,MGST3,FHL2,WWC1,ARHGAP32,MBNL2,TBC1D2,DHX32,TMCO3,FCHO2,PMEPA1,PLOD2,FAT1,SLC7A5,SVIL,TUFT1,PLD1,PTGES,SFN,DIRC2 |
| 8.404e-06 | -11.69 | LINDGREN_BLADDER_CANCER_CLUSTER_2B | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2B | 368 | 63 | 17377 | 1707 |
LATS2,RUNX2,ALOX5AP,IL32,FLVCR2,C4A,STXBP6,DNAJC3,ST6GAL1,LMCD1,SELL,COL18A1,NRN1,SLC7A2,CHSY1,LCP2,DOCK2,PCDH7,EFEMP1,HMGCS1,MAP1A,ABI3BP,SLC16A2,STARD4,SREBF1,ACTA2,DHRS12,TOX,PROS1,MOXD1,ETV1,PDGFRB,TBC1D8,MICAL2,ALDH2,COL6A2,NR4A1,MPP1,TES,PREX1,SDC3,MAFB,PRICKLE1,C1R,TNS1,COTL1,RARRES2,PALLD,JAM3,GPC6,ISG20,EBF1,ENTPD1,GSN,HLF,MYADM,RND3,HEYL,RBPMS2,RGS10,GEM,TPM1,STOM |
| 8.407e-06 | -11.69 | V$NKX62_Q2 | MSigDB lists | V$NKX62_Q2 | 227 | 44 | 17377 | 1707 |
CGN,LRFN5,FARP1,C1QTNF3,FGF13,CHCHD7,RHOBTB1,PLAG1,MYO1B,CADM2,RPL34,EPB41L3,BACE2,MARVELD2,FLRT3,TMEM143,BEND4,MARCKS,FIGN,MYT1,C15orf41,MED12L,NKX2-1,MSTN,MSRB3,CCNG1,PRDM1,ATOH1,ZFPM2,NAALADL2,ZIC1,GNAI1,BCL11A,ADAMTS17,SMAD3,IKZF3,PELI2,SLCO5A1,ZBTB20,DLG2,UNC5B,SHOX2,FILIP1,MEF2C |
| 8.583e-06 | -11.67 | bone-femur-other-chondroblastoma | COSMIC cancer mutations | bone-femur-other-chondroblastoma | 193 | 39 | 17385 | 1698 |
PHACTR3,MRC2,DNM3,CACNG3,NSUN6,CLSTN2,NKAIN2,GALNT13,CREB5,KIAA1217,HMCN1,PCDH7,ZFYVE28,FAM189A1,TACC2,COL25A1,ATRNL1,FHIT,COG3,SLCO4C1,SLIT2,ADCY1,PREX1,MARS,SNTB1,B4GALNT3,ARMC4,NRG3,PLOD2,FBN1,PRKCB,PELI2,RASGRF2,CCBE1,ARHGAP28,TMEM117,TMEFF2,CDH2,HS6ST3 |
| 8.643e-06 | -11.66 | GO_NEURON_MIGRATION | MSigDB lists | GO_NEURON_MIGRATION | 106 | 26 | 17377 | 1707 |
DISC1,GPM6A,MARK1,CELSR1,FGF13,CELSR3,DCC,RAPGEF2,GATA3,SATB2,NTRK3,GAS6,ATOH1,DNER,FGFR1,DDIT4,NAV1,GATA2,LHX6,MATN2,KIAA0319,PRKG1,NRP1,SEMA3A,NKX2-1,MEF2C |
| 8.772e-06 | -11.64 | blood vessel development | biological process | GO:0001568 | 472 | 75 | 17256 | 1658 |
AMOTL1,ACVR1,ID1,RECK,ARHGAP22,COL18A1,ADAMTS6,PRKCA,TYMP,TGFBR3,ITGB3,DAB2IP,SLIT2,PDGFRB,CYP1B1,CEMIP2,ADM2,FZD4,YAP1,WNT11,ACVR2B,JAM3,FGFR1,WARS,GJC1,HPSE,CCBE1,PTK7,APELA,HPGD,KLF5,SEMA3C,BMPR1A,UNC5B,NRP1,VASH2,HEY1,PCSK5,MEF2C,EFNB2,BMPR2,FN1,FZD8,SLC12A6,OVOL2,EPHB1,ACTA2,TSPAN12,DYNC2H1,LOXL4,SMAD6,SYK,NOS3,VEGFC,FGFR4,VAV3,ATP5IF1,SH2D2A,NR4A1,RAPGEF2,PRICKLE1,CALCRL,PRDM1,ZFPM2,LEPR,HOXA1,GPLD1,HEG1,PRCP,XBP1,EGFL7,BMP4,CDH2,DHCR7,DDIT3 |
| 8.847e-06 | -11.64 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | 158 | 34 | 17377 | 1707 |
EPHA3,PCDH18,ACVR1,ZCCHC24,PTPN21,C20orf194,APBA1,SPEG,FKBP9,FBXO32,SMTN,ACTA2,TLN2,PERP,SNAI2,ATL1,CAPN5,EFNA3,KIAA1324L,MSRB3,FERMT2,PRICKLE1,SAV1,TTC28,MAGI3,ENPP1,CACHD1,DDAH1,VPS37D,THBS4,UACA,MBOAT2,CTNND2,KCTD1 |
| 8.847e-06 | -11.64 | GSE3565_DUSP1_VS_WT_SPLENOCYTES_UP | MSigDB lists | GSE3565_DUSP1_VS_WT_SPLENOCYTES_UP | 158 | 34 | 17377 | 1707 |
LATS2,RUNX2,TTC39B,LGALS3,ARL15,XYLT1,KIF5C,COBLL1,IL18R1,HOPX,SEMA4F,SOAT2,PROS1,CERS4,TMEM37,SNX10,MICAL2,EBPL,TMEM65,HIP1,VIM,ATOH1,PRDM1,DOCK5,SMPDL3B,PTPRJ,IKZF3,MYADM,CCDC146,ERN1,PCGF2,LRRK1,NRP1,ATP2B4 |
| 8.857e-06 | -11.63 | digestive system development | biological process | GO:0055123 | 141 | 31 | 17256 | 1658 |
EPB41L5,LGR4,NKX3-2,WLS,ITGA6,DCHS1,GATA3,ASS1,WNT11,PRDM1,ACVR2B,OVOL2,RARRES2,SAV1,SMAD3,FAT4,GATA2,DACT1,RBPMS2,XBP1,WDR19,KLF5,HOXD13,OXTR,BMP4,SHOX2,BARX1,COBL,SIX2,PCSK5,GLI1 |
| 8.974e-06 | -11.62 | bZIP | interpro domains | IPR004827 | 54 | 17 | 18492 | 1811 |
CREB3L2,CEBPB,HLF,ATF4,BACH2,JDP2,XBP1,NFE2L1,MAFB,ATF3,CEBPA,DBP,CREB5,BATF,CEBPD,DDIT3,BATF3 |
| 9.056e-06 | -11.61 | pleura | COSMIC cancer mutations | pleura | 4983 | 564 | 17385 | 1698 |
ARHGAP26,AASS,PRSS12,DNAJC3,NPM1,STAT5B,CADM2,SNX9,NOS1AP,SKI,PCDH7,BAG3,FBXO32,IKZF5,PMAIP1,PPFIA2,FAAH2,RAP2A,RAB26,PPP2R2B,NKX2-1,SMAD9,KLHL23,TGFA,LRRK2,FEZ1,PRKAR2B,INTS6,ALDOA,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,LPP,MEF2C,CARS,GNG12,TMEM63C,LATS2,ITGA6,BTBD9,GPSM2,FOXG1,BBS9,CHN1,SYCP2,BNIP1,FRY,BACE2,SRGAP1,TOX,CADPS2,ALPK1,LOXL4,HMGCR,PNP,STAT4,EFHC2,RYR2,HIP1,SMARCD3,DHX32,BEX4,ADAMTS3,CLMN,HOXD13,SPRED3,FBXO27,DNM3,TMSB15A,GALNT6,RGS20,IL13RA1,GRK6,COLEC10,RNF150,DACT1,MAGEA3,FAM133A,PJA1,FAM155B,ARL4D,RAB27B,DNAH5,SNX10,FZD1,MYLK3,GAPDH,FZD4,WNT11,RAB38,FGFR1,GJC1,IRS2,CXCL10,ARHGAP21,INPP4B,TNFSF15,RAB30,FARP1,WDR17,EDA2R,FZD8,PLAG1,BIK,IPO5,GAS6,PKN1,EPHB1,TSPAN17,BEX2,COL27A1,PCBP4,MCF2L,GAS2L3,GHR,ZFP36L2,MED12L,FES,BCL7A,RAB6B,MCF2L2,RAPGEF2,AK4,RASA3,SNTB1,PTPRC,TRIB3,ID3,NSD1,GNAO1,AKT3,XBP1,NEK11,PIP5KL1,BMP4,HK1,FOXA1,BTRC,TRIM2,FGF13,TRIM16,ITPR2,NUP62CL,NOVA1,PLS3,RND2,CPNE2,FKBP9,RPS6KA2,TM9SF2,AADAT,MARVELD2,ITGB3,TMEM132E,TLN2,ENO1,ETV1,RAPGEF5,ITGB7,MARK1,COL4A3,CR2,PLEKHA1,BATF,SESN1,PLEKHB1,DYRK1B,TRIM9,KCNMB4,MAP2,GNB4,TECPR2,ERN1,TNFRSF1A,PIK3C2B,MLLT3,RRAGD,KCNV1,PRKAA2,RGS16,RUNX2,SETBP1,DOK5,FHOD3,HSPA12B,NUMBL,IGF1R,BCHE,GATA2,PDE10A,LRP6,BNIP3,PTPRCAP,FBXL2,PAK1,FGFR4,CHSY3,MID2,SPATA13,PPFIA4,STRADB,OBSCN,MAFB,SLITRK5,KHDRBS2,MAPKAPK2,PLD1,RNF122,SFN,ID1,CFH,AKAP5,DOCK1,RNF24,NTRK3,KIF21B,PPP1R9A,SEMA6A,PCLO,DDX60L,SLC22A17,TACC2,MYO3B,BCL6,GLI1,LRRC8B,ACO1,FGF12,RNF125,VIM,FBXO36,PAGE5,FRK,SMAD3,RANBP2,PTPRJ,PTK7,ITGA2,PTPRS,MAOA,SEPT5,CTNND2,CNTN1,HEY1,PCDH18,DYRK3,IL32,BMPR2,KLHL13,GRB14,NLRP14,RASD1,USP30,PPP2R3A,FOXP2,TECPR1,MAP1A,RASD2,TSC22D1,SGK1,PCK2,SYK,ATP2B1,CES3,DUSP1,DLGAP1,PPP1R3D,FOXN3,CRIP2,LITAF,NUAK2,PALLD,MGMT,DKK1,FAT4,FBN1,ZNF214,FMO4,ZNF808,SH3BGRL2,PAX9,PTGES,KIF1B,CGN,MYCBP2,ACVR1,PAGE1,LANCL3,LGR4,DUSP8,LDLR,PPFIBP2,GATA3,ENAH,ADAMTS6,PRKCA,DACH2,RAC3,HECTD2,STK24,SLC9A7,TRPS1,ZFYVE28,SLC16A2,CHRDL1,ACVR1C,KLHL4,LRMP,DNAJC6,DEPTOR,BNIP3L,ACVR2B,ZDHHC14,SAV1,GNAI1,AHRR,HLF,PLK2,RASGRF2,SERPINI1,DSEL,MAPK13,SPRY4,UNC5B,TANC2,KLF8,INPPL1,ALOX5AP,PTPRD,ST6GAL1,MLF1,OPHN1,TNFRSF10C,DYNC1I1,TNFRSF19,CHD5,GAS1,MECOM,NAV1,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,CPXM2,MPDZ,SAMD13,PRR16,RIMS2,RNF152,PTCH2,RPL26,PLEKHA8,TBC1D8B,COL4A4,DCHS1,RAPGEF4,KIAA1324L,RABAC1,CDC42BPA,CCDC85A,PLCB1,FAM162A,TMEM74,MMP15,PKN3,PMEPA1,LRRIQ3,IQSEC2,DHCR7,SMYD3,AMPD1,FRMPD3,EPHA3,PLA2G4A,PCSK1N,RHOD,RNF144A,PLXNA2,CHUK,COL14A1,DDR1,ZFYVE9,CCDC120,SPEG,ALDOC,STARD4,NAP1L3,PDE4D,SERPINH1,GAB2,TRDMT1,VNN2,PDK1,PREX1,NLGN4X,ATF3,PRKCQ,PNMA6A,SATB2,PYGO1,TBC1D16,ZNF711,IKZF3,PRKCB,CCNA1,GRB10,BMPR1A,CTTNBP2,MID1,HACE1,MYO1D,MXI1,HERC5,ARL2,RGS7,INPP1,NEDD4,RGS17,AFF2,SGK3,SLC6A15,SMAD6,SPRY2,VAV3,PXN,ALDH2,MPP1,PTPN13,CACNA1E,ZDHHC15,GPLD1,CEBPB,FGR,TERT,TNFRSF17,DDIT3,PTPN21,IKZF2,KREMEN1,FKBP11,ARHGEF10L,SIPA1L2,PPM1E,AKAP7,POF1B,HRK,SLC2A12,CTTN,PTPRE,PRKACB,PDGFRB,RASGRP1,TNK2,SESN2,YAP1,COTL1,TMEM47,ROR1,SGK2,RNF44,SERGEF,AK1,HPSE,NCOA7,PPARGC1A,TNFSF4,MAGI2,BCL11B,RHOBTB1,FBXO4,JDP2,SATB1,DDIT4,RNF141,RNF148,SNX7,RHOQ,SLITRK2,MSTN,DUSP9,WWC1,SDC3,PRDM1,CSAG1,RAB31,HK2,PTPRN2,FNBP1L,NKX2-8,CXCR5,NEK10,PSTPIP2,PLEKHA5,ARHGAP22,MORC4,HECW2,BCL6B,PIBF1,PDZD8,CDC14B,RPS6KL1,PPFIBP1,ZNF521,MAP7,ACVR2A,POU2F2,MET,HSPA2,SUSD3,FER,PTPRU,PTPN6,CD40,BCL11A,TPK1,MAGEA12,TRIM34,BACH2,KPNA3,EIF4EBP1,DUSP19,RGS10,DISP1,RNF130,LIFR,MAST1,TNIK,ENO2,ARHGEF11,REL,TNFSF13B,COL4A5,IGF2BP2,CHN2,PRKCD,TRIM3,RRAS2,FKBP14,TNFRSF11A,CARD6,RIN2,USP2,RAB3B,CYTH3,SYBU,PRRG1,MARS,AGAP2,ARHGAP32,CCNG1,ADAMTS17,SUGT1,EDA,RND3,MAP2K6,KIF21A,GEM,RNF157,MMP16,IL9R,ABCG1 |
| 9.173e-06 | -11.60 | V$CREBP1_01 | MSigDB lists | V$CREBP1_01 | 165 | 35 | 17377 | 1707 |
PRDM8,GABRR2,CREB5,IKZF2,ARHGAP44,ZFYVE9,EEF2,GRHL1,PRELID1,BCL6,TSC22D1,PRKG1,KLF9,RBMS2,MED12L,UNC5C,GPM6A,ERGIC1,USP2,RNF145,CRIM1,ATF3,MBNL2,HERPUD1,NEGR1,BCL11A,ZNF711,SMAD3,DAGLA,PMEPA1,MAP2K6,PELI2,MPP2,SPRY4,OSBPL6 |
| 9.201e-06 | -11.60 | positive regulation of multicellular organismal process | biological process | GO:0051240 | 1608 | 205 | 17256 | 1658 |
ACVR1,LGR4,TRIM16,LDLR,VAMP8,GATA3,STAT5B,CEBPA,ABAT,PRKCA,NOS1AP,F3,RND2,TGFBR3,ITGB3,CTTN,PACSIN1,TLR4,ENO1,SLIT2,IL1RAP,RASGRP1,PDGFRB,CYP1B1,GCNT2,ATF4,LRRK2,YAP1,FEZ1,ACVR2B,F12,GPRC5B,HPSE,NCKAP1L,CCBE1,PLK2,ADRB1,BMP1,ZBTB20,SEMA3C,MAPK13,SERPINI1,OXTR,DLX2,TPM1,NRP1,TNFSF4,VASH2,MAGI2,MEF2C,EFNB2,RUNX2,FN1,LGALS3,PTPRD,ZHX3,FOXG1,IL18R1,IL17D,MCOLN2,NUMBL,CA2,GATA2,MYC,FLRT3,LRP6,GRIP1,INAVA,TOX,CHRM3,RIMS2,NOS3,HMGCR,EPB41L5,PAK1,ENAM,BDNF,DISC1,SLITRK2,PNP,VLDLR,RYR2,NSD2,SLITRK5,SMARCD3,PLS1,PRDM1,PLCB1,BAIAP2,NEGR1,MAPKAPK2,ADGRB3,HEYL,CSF1,HK2,TRPC3,SEMA3A,TESC,SHTN1,EPHA3,PRKN,NBL1,AMOTL1,DOCK1,IL15,PLXNA2,CHUK,NTRK3,NRXN1,PIBF1,PPP1R9A,CBLN1,SEMA6A,SCIN,TLR3,UNC13B,BCL6,ADGRL1,ACVR2A,DAB2IP,PDE4D,MET,ZNF488,ZNF365,GLI1,CTH,FZD1,PHLDB2,GAPDH,FZD4,ADM2,SHANK2,PRKCQ,WNT11,GSTO1,ATOH1,AMIGO1,CD40,DOCK5,FGFR1,SMAD3,PRKCB,APELA,PTK7,WWTR1,ITGA2,HGF,BMPR1A,ATG5,COBL,CNTN1,WASF3,ROBO2,C1QTNF3,BMPR2,CD276,PLAG1,APBB1,CLSTN2,GAS6,P2RY1,OVOL2,EPHB1,ZNF219,GDPD5,BMP6,ADGRB2,NKX6-1,FOXP2,LRRN1,SCN1B,GHR,TFAP2A,AFAP1L2,SH3PXD2B,FIG4,YBX3,IQGAP3,TNFRSF11A,TESPA1,SYK,FES,TRPM4,PDLIM7,VEGFC,KDM5B,RAPGEF2,RACK1,ZFPM2,TLR6,HEG1,MAP1B,GPLD1,DKK1,CEBPB,DDAH1,FGR,TERT,AKT3,XBP1,MYRF,BMP4,SHOX2,DDIT3,FOXA1 |
| 9.219e-06 | -11.59 | regulation of biological process | biological process | GO:0050789 | 11524 | 1185 | 17256 | 1658 |
ARHGAP26,THOC5,GRIK2,RECK,NPM1,CTBP2,CEBPA,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,CPE,POU3F3,EIF4E3,DCC,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,KCND3,FGF17,INTS6,PYCR1,ZNF788P,ENPP1,WIPF3,MAP9,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,INPP5F,DIRAS1,TPM1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,TOX,CADPS2,FIGN,JAM2,ZNF385A,KCNQ3,ARID5B,ZNF605,FHL2,FASN,HIP1,SHISA2,SNAP25,ARRDC4,TEX15,RPL28,CLMN,LAPTM4B,HOXD13,CDH2,SHTN1,DOCK9,MTG1,TFCP2L1,ADD2,MAPK4,GRK6,PLPP1,TLR3,MAGEA3,ZNF365,MYT1,KIAA1549,KCNB2,FZD1,MYLK3,GAPDH,NECAB1,PFKFB2,ADM2,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GJC1,CXCL10,ARHGAP21,WFS1,APELA,LAMB1,LRRC27,RAB30,CGB2,CKAP2,BACE1,PLAG1,FZD8,ESRP1,CD276,BIK,UBAC2,PSD3,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,VEGFC,LZTS3,RAB6B,RASA3,NSD1,RPL12,NEK11,BMP4,ATP2B4,PHC1,TLL2,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,FAM13A,RND2,RPS6KA2,SEC16B,ITGB3,TBC1D32,ENO1,RAPGEF5,ZNF391,DBN1,KCNIP3,MARK1,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,SESN1,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,ADGRA3,NEUROG2,TC2N,ADGRL2,CACUL1,RRAGD,LONRF1,TYRO3,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,FHOD3,SPIRE1,RNF180,NUMBL,ZBTB38,ZNF440,HS3ST5,LRP6,ADCY6,MED7,VGLL4,DPYSL5,BTNL9,EFNA3,GPSM1,SLITRK5,MAFB,STRADB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,KCNK15,GRIK4,PLD1,SEMA3A,ID1,DOCK1,RHPN2,NTRK3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF362,IDI1,BCL6,SNAI2,IGFBP3,RPS13,INTU,CSN2,LRRC8B,TMEM65,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,PAK5,KLHL13,MCTP2,RASD1,PRDM8,USP30,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,TSPAN13,SYK,ATP2B1,CES3,PCSK6,DUSP1,FOXN3,CRIP2,PRICKLE1,FERMT2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,CD37,DDAH1,DOCK7,FBN1,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,LGR4,LDLR,VAMP8,PRKCA,TRPS1,TYMP,ZFYVE28,KCNS3,ACVR1C,WISP3,BNIP3L,EFHC1,GNAI1,SH3RF1,BMP1,MAPK13,SERPINI1,SPRY4,NRP1,SPOCK3,KLF8,MRC2,TBC1D1,MLF1,DHCR24,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,RALGPS2,NOVA2,MYC,C1QL4,SREBF1,PRKG1,GRIP1,MAST4,PRR16,GPR161,BOD1,PTCH2,RPL26,DISC1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,PLEKHH2,PELI2,THBS4,WDR19,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SMYD3,NBL1,TCTN2,RHOD,MSR1,PLXNA2,TMEM170B,DDR1,TIAM2,ZFYVE9,SPEG,ASNS,ZNF438,POU5F1B,SHF,PDE4D,GAB2,SHANK2,PREX1,NLGN4X,ATF3,SATB2,CBY1,ATP1B1,PYGO1,ATOH1,ISG20,SNCA,PATJ,ZNF711,IKZF3,BEX3,CCNA1,ZNF704,HPGD,BMPR1A,MID1,STON2,PURG,COBL,HACE1,MYO1D,IGFBP6,EPS8,HERC5,NDFIP2,TPD52L1,INPP1,PHLDA2,ADGRB2,GSAP,RASSF8,LRRC55,IRX5,GPR155,AFF2,DYNC2H1,TBC1D9,ERRFI1,SMAD6,SLC40A1,VAV3,SH3BP2,PXN,ARHGEF28,GSTM2,PTPN13,RPL21,HOXA1,ZFP62,TERT,MCC,SVIL,LRRK1,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,F3,GSDME,ADPRHL1,EPCAM,SIPA1L2,PPM1E,ABI3BP,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,CEMIP2,JPH1,YAP1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,OXTR,PPARGC1A,TNFSF4,MAGI2,FRMD5,GPR63,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,SPINK5,RNF141,EEF2,SLC30A4,ZNF354A,INAVA,CAND2,CEBPD,ZNF629,ATP5IF1,RHOQ,SLITRK2,HERPUD1,RIPOR2,PLAGL1,NCR3LG1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,FNBP1L,NKX2-8,SORBS1,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,REEP1,FABP6,ACVR2A,FHIT,PROS1,SP140L,ALG10B,PRAME,ANTXR2,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,ZNF569,BCL11A,BATF3,CAMK2N1,ARMC4,ZNF93,TRIM34,EIF4EBP1,RBPMS2,RGS10,DUSP19,MAST1,TSPAN15,ARHGEF11,CMTM8,TNFSF13B,SSX1,SLX1B,COL4A5,IGF2BP2,OVOL2,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,AFAP1L2,IPCEF1,TESPA1,PNMA2,CARD6,USP2,KDM5B,CRIM1,HNF4G,SYBU,ASAP3,TLR6,LRAT,LEPR,CTIF,ICA1,EDA,RND3,ACER2,CTSV,UACA,RPS12,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,LSM11,DNAJC3,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,BAG3,TGFBR3,PPP1R26,FBXO32,PMAIP1,RAB26,TSHR,ZBED9,NKX2-1,MEIS2,SMAD9,TGFA,CAP2,WLS,F12,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,LATS2,GNG12,CYP2J2,SLK,SYCP2,BNIP1,BACE2,CACNB2,ZIC5,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,ZNF518B,FMNL2,GFRA1,CHRM3,LRP12,RPS23,HMGCR,FADS1,BDNF,ENAM,PNP,MYO10,STAT4,CALCRL,SMARCD3,RYR2,PLS1,C1R,TAF4B,OR11H4,MBNL2,CPEB1,BEX4,SH3GL2,ADAMTS3,INHBE,CDH17,SPRED3,TRPC3,BTC,DNM3,ZNF516,TMSB15A,C4A,RGS20,PKP2,IL13RA1,LCP2,NRXN1,COLEC10,CDS1,TXNRD3,GPR15,EPB41L3,CHRNA5,KMO,CNKSR3,DACT1,RTKN2,RAB27B,SYNGR3,PERP,DOCK8,SCN3A,SSH3,FZD4,NKX3-2,KCNH5,ATF7IP2,PXYLP1,RAB38,TTC28,FGFR1,IRS2,GYPC,ZNF697,PEMT,GPR160,WWTR1,PLEKHG1,INPP4B,PAM,TNFSF15,DBP,KLHL31,HOXB9,FARP1,ROBO2,EDA2R,C1QTNF3,IPO5,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,NEO1,BHLHA15,MCF2L,MYO6,FES,ULBP1,BCL7A,CLYBL,RAPGEF2,MCF2L2,GAREM1,RACK1,HEG1,PTPRC,GALNT3,TRIB3,ID3,PLPPR2,GNAO1,AKT3,XBP1,SHOX2,DOCK6,BTRC,FOXA1,TPT1,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,SYT14,NOVA1,EOMES,TCAF2,KCNN2,KCNAB1,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,PLPP2,PLEKHA1,TCERG1L,BATF,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,UBASH3B,RASL11B,SETBP1,MLC1,IL18R1,EFEMP1,KIAA1958,IGF1R,SEMA4F,GATA2,BCHE,ABCA5,PDE10A,BNIP3,FBXL2,FGFR4,PAK1,MID2,UNC5C,HOMER2,TCEA3,SPATA13,PDE8A,MAPKAPK2,CSF1,HEYL,TESC,SFN,SIX2,PRKN,AVPI1,CFH,AKAP5,RBFOX2,ZNF83,OR51B4,SLC7A2,LPIN3,PCLO,CBLN1,CTNNA2,CYP26A1,TBC1D19,RIDA,SLC22A17,LHX6,ADGRL1,SCN2A,ZNF488,CTH,GLI1,TMEM67,EVL,TUBA1A,NOP53,FGF12,GSTO1,RARRES2,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ABI3,ITGA2,KCNG1,SEPT5,ZNF701,CNTN1,LPAR2,IL32,GRB14,NLRP14,APBB1,SELL,GABRG2,ARHGAP44,PPP2R3A,MAP1A,RASD2,EIF1,PRICKLE2,SH3PXD2B,KLF9,PCK2,SLC45A3,MOB1B,MICAL2,PPP1R3D,NUGGC,NUAK2,LITAF,NPDC1,MAP10,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,DLG2,ZNF808,MYRF,PAX9,RPL4,THAP10,TBC1D4,CGN,MYCBP2,ACVR1,PPP4R4,LANCL3,DUSP8,ATP8A1,GATA3,RAC3,AARS,DACH2,NCS1,STK24,MOK,FAM168A,CFHR1,CHRDL1,ATRNL1,SP140,PACSIN1,RCAN3,PLTP,TBC1D8,DCDC1,NR6A1,DNAJC6,DEPTOR,MEF2B,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,GPR150,AHRR,HLF,NCKAP1L,CCBE1,RASGRF2,PLK2,SEMA3C,UNC5B,SPART,ZBED8,LZTS1,EFNB2,INPPL1,CELSR1,ZHX3,PTPRD,GABRB2,SCN8A,SLC25A27,OPHN1,GTF2IRD1,TNFRSF10C,SLC1A3,CHD5,MYORG,RPL13A,MECOM,MCOLN2,CNTN4,PIK3AP1,PRELID1,OPN3,TSPAN12,RIMS2,IGSF3,RNF152,EPB41L5,QSOX1,TBC1D8B,TCF24,PLCB1,ZNF558,FAM162A,DAGLA,PMEPA1,PKN3,IQSEC2,EPHA3,PLA2G4A,PCSK1N,AMOTL1,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,TBC1D30,ZNF827,STARD4,DAB2IP,MARCKS,SERPINH1,PDK1,SOX21,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,ATG5,MAPK10,NR3C2,KCTD1,RPS20,WASF3,MXI1,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,KDM7A,RGS17,SOAT2,SGK3,RALGAPA2,PRKG2,FIG4,YBX3,GFI1,SPRY2,PFKFB4,SYNPO2,ARAP2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,ZNF714,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,PCGF2,TUFT1,GRIN2D,OCLN,B4GALT7,ATP1A3,EXPH5,MVK,HEBP1,TNFAIP8L2,JCHAIN,ABAT,RBM11,DNER,IKZF2,CACNB4,KREMEN1,ARHGEF10L,TUBB4A,CYP51A1,GRHL1,AKAP7,DLX6,HRK,EPHB6,PCOLCE2,FANK1,PTPRE,OR2W3,SLIT2,RASGRP1,PRKACB,GPM6A,CAPN5,ZNF565,ROR1,SERGEF,GRK3,C8orf88,NCOA7,APBA2,BCL11B,UST,FN1,JDP2,ATP6V1E2,CD7,SATB1,PHGDH,ADGRG6,DDIT4,CA2,RPS11,EBF4,NCEH1,BARX1,NOS3,RAX,IL17RD,GPR176,MSTN,SH2D2A,EDEM3,WWC1,DUSP9,PRDM1,ADGRB3,HK2,EGFL7,CREB3L2,CXCR5,NEK10,ZSWIM5,IL15,CELSR3,TDRKH,BCL6B,DOCK2,SP8,ZSCAN5A,SETDB2,UNC13B,RPS6KL1,ZNF521,STEAP3,GULP1,MET,POU2F2,WWC2,ZNF460,HSPA2,DPP10,PHLDB2,FER,TES,SYNJ2BP,DOCK5,WARS,MSC,BACH2,SOHLH2,DISP1,LIFR,OR51B5,TNIK,REL,LRP4,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,EHD3,DSG2,KIAA0319,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,GRID1,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,RERE,MAP1B,GPR37,TIFA,MYADM,GCSAM,MPP7,NACC2,MAP2K6,PRCP,GEM,MAP3K20,STOM |
| 9.323e-06 | -11.58 | REACTOME_COLLAGEN_FORMATION | MSigDB lists | REACTOME_COLLAGEN_FORMATION | 54 | 17 | 17377 | 1707 |
COL9A3,COL6A2,COL4A3,COL4A4,COL4A5,COL14A1,COL27A1,COL22A1,PLOD2,ADAMTS3,COL25A1,BMP1,COL19A1,PCOLCE2,SERPINH1,COL9A2,TLL2 |
| 9.360e-06 | -11.58 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | 752 | 110 | 17385 | 1698 |
PHACTR3,TRIM16L,RASAL2,AASS,DOCK1,GALNT6,FHDC1,COL18A1,GATA3,NPM1,STAT5B,CEBPA,SEZ6L2,DENND3,DOCK2,PCLO,HMCN1,TRPS1,EPDR1,SPEG,IDI1,TACC2,PPFIBP1,KCNS3,MAP7,NBEA,JAKMIP2,MET,DNAH5,NEB,PDGFRB,SMAD9,SPOCD1,NR6A1,KLHL23,PTPN6,LRRK2,DNAJC6,TRAM1L1,ADCY1,ATOH1,CA13,FGFR1,ZNF711,IRS2,RANBP2,ZNF93,ERN1,PIK3C2B,SPRY4,DENND5B,KCNV1,BCL11B,ANKRD13D,CELSR1,FN1,ROBO2,PTPRD,ARHGEF11,ATP9A,C1orf226,PRSS35,OPHN1,CLSTN2,SETBP1,CBS,TJP1,DYNC1I1,COL27A1,MTUS1,IGF1R,SLC30A4,GATA2,FRAS1,MPDZ,TOX,ALPK1,MOXD1,NIPAL2,GFI1,SPRY2,GPR161,CAND2,MN1,RAX,SYNPO2,COL4A4,PTPN13,RAPGEF2,GRID1,RYR2,MARS,PRDM1,KHDRBS2,HOXA1,MAP1B,PTPRC,TEX15,FBN1,FAT1,TMEM117,CLMN,UACA,KIAA0513,KIF21A,SPRED3,SLFN5,SEMA3A,XKR4,SFN |
| 9.360e-06 | -11.58 | acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_T_cell_leukaemia | 752 | 110 | 17385 | 1698 |
PHACTR3,TRIM16L,RASAL2,AASS,DOCK1,GALNT6,FHDC1,COL18A1,GATA3,NPM1,STAT5B,CEBPA,SEZ6L2,DENND3,DOCK2,PCLO,HMCN1,TRPS1,EPDR1,SPEG,IDI1,TACC2,PPFIBP1,KCNS3,MAP7,NBEA,JAKMIP2,MET,DNAH5,NEB,PDGFRB,SMAD9,SPOCD1,NR6A1,KLHL23,PTPN6,LRRK2,DNAJC6,TRAM1L1,ADCY1,ATOH1,CA13,FGFR1,ZNF711,IRS2,RANBP2,ZNF93,ERN1,PIK3C2B,SPRY4,DENND5B,KCNV1,BCL11B,ANKRD13D,CELSR1,FN1,ROBO2,PTPRD,ARHGEF11,ATP9A,C1orf226,PRSS35,OPHN1,CLSTN2,SETBP1,CBS,TJP1,DYNC1I1,COL27A1,MTUS1,IGF1R,SLC30A4,GATA2,FRAS1,MPDZ,TOX,ALPK1,MOXD1,NIPAL2,GFI1,SPRY2,GPR161,CAND2,MN1,RAX,SYNPO2,COL4A4,PTPN13,RAPGEF2,GRID1,RYR2,MARS,PRDM1,KHDRBS2,HOXA1,MAP1B,PTPRC,TEX15,FBN1,FAT1,TMEM117,CLMN,UACA,KIAA0513,KIF21A,SPRED3,SLFN5,SEMA3A,XKR4,SFN |
| 9.388e-06 | -11.58 | - | gene3d domains | 2.60.40.150 | 154 | 35 | 8148 | 867 |
PLA2G4A,DOC2A,RASAL2,DOCK1,SYT12,MCTP2,HECW2,PRKCA,SYT14,DOCK3,DOCK2,PCLO,NEDD4,SYDE2,RAB11FIP5,CPNE2,UNC13B,PRKCD,DAB2IP,WWC2,RIMS2,DOCK8,CAPN5,RASA3,WWC1,PRKCQ,PLCB1,DOCK5,DOCK7,PRKCB,INPP4B,PIK3C2B,TC2N,DOCK6,DOCK9 |
| 9.520e-06 | -11.56 | chr13q14 | MSigDB lists | chr13q14 | 65 | 19 | 17377 | 1707 |
FAM124A,TDRD3,CKAP2,LACC1,FNDC3A,INTS6,SETDB2,KPNA3,ATP7B,TSC22D1,GTF2F2,ALG11,CCDC122,CAB39L,DHRS12,COG3,ESD,THSD1,TPT1 |
| 9.520e-06 | -11.56 | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | MSigDB lists | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | 65 | 19 | 17377 | 1707 |
GCA,COL9A3,CD55,ATP8A1,ABAT,SATB1,FHOD3,MTUS1,MMP15,TEX15,MPP7,PMAIP1,PLXDC2,PRKG1,NBEA,CERS4,PLTP,ZNF385A,PERP |
| 9.570e-06 | -11.56 | human chr13q32.1 | chromosome location | human chr13q32.1 | 21 | 9 | 26185 | 1967 |
ABCC4,SOX21,DNAJC3,RAP2A,GPR180,TGDS,MBNL2,SOX21-AS1,HS6ST3 |
| 9.576e-06 | -11.56 | asymmetric synapse | cellular component | GO:0032279 | 229 | 43 | 18223 | 1724 |
DNM3,CACNG3,BMPR2,GRIK2,LRP4,CLSTN2,PSD3,ADD2,P2RY1,PPP1R9A,PCLO,CTNNA2,ARHGAP44,NCS1,EPB41L3,LIN7A,MPDZ,BNIP3,CHRM3,DLGAP1,DISC1,LZTS3,CAP2,SHANK2,HOMER2,DNAJC6,GRID1,NLGN4X,ARHGAP32,CPEB1,BAIAP2,HOMER3,MAP1B,CAMK2N1,GRIK4,MAP2,MPP2,PTPRS,GRIN2D,DLG2,CDH2,MAGI2,LZTS1 |
| 9.620e-06 | -11.55 | PRC2_EZH2_UP.V1_DN | MSigDB lists | PRC2_EZH2_UP.V1_DN | 179 | 37 | 17377 | 1707 |
RGS16,DUSP8,FLVCR2,ST6GAL1,ACTL8,SETBP1,KCTD12,COL4A5,ZNF215,COLEC10,NOVA1,SLC19A2,TBC1D19,RGS17,KIAA0895,OPN3,PRKG2,SLC6A15,TSPAN13,VWA5A,ETV1,SMPDL3A,FZD1,TMC7,C3orf52,PLCB1,TTLL7,DCBLD2,GPR37,POPDC3,PMEPA1,ITGA2,AHNAK2,KIAA0513,SEMA3A,NR3C2,PKIA |
| 9.620e-06 | -11.55 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP | 179 | 37 | 17377 | 1707 |
LATS2,NBL1,INPPL1,ID1,JDP2,GTF2IRD1,RASL11B,NDRG2,ZFYVE9,FKBP9,CNKSR3,MYC,SGK1,TSPAN12,PDE4D,PJA1,WWC2,ARL4D,SPRY2,CEBPD,DUSP1,SNX7,NR4A1,FOXN3,NUAK2,NFIA,ATF3,TNS1,CEBPB,ID3,RND3,PLK2,PLD1,SPRY4,GEM,TPM1,TC2N |
| 9.631e-06 | -11.55 | GO_SUBSTRATE_DEPENDENT_CELL_MIGRATION | MSigDB lists | GO_SUBSTRATE_DEPENDENT_CELL_MIGRATION | 25 | 11 | 17377 | 1707 |
PTPRC,VEGFC,EPB41L5,ITGA2,OPHN1,CTTN,NRP1,SEMA3A,SLIT2,SNAI2,FGFR1 |
| 9.748e-06 | -11.54 | GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_DN | MSigDB lists | GSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_DN | 186 | 38 | 17377 | 1707 |
EFNB2,MYO1D,EHHADH,BMPR2,PLEKHA5,MYO1B,EPS8,CTBP2,SCIN,EPCAM,DSG2,GHR,STC2,TSC22D1,MAP7,LIMCH1,MYO6,ERRFI1,CPE,CYP1B1,TRDMT1,FZD4,NR6A1,WLS,VLDLR,WWC1,HOXA1,CPEB1,GNAI1,IRS2,MSC,LAMB1,SLCO5A1,SQLE,BMPR1A,GEM,SIX2,LPP |
| 9.748e-06 | -11.54 | GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_UP | MSigDB lists | GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_UP | 186 | 38 | 17377 | 1707 |
EML5,SERINC5,FN1,KLHL13,MLF1,ST6GAL1,COL4A5,PGAP1,EYA4,EFEMP1,RNF150,TGFBR3,ATRNL1,AGL,TMEM56,HRASLS,CTH,ANTXR2,RAB3B,RHOQ,BTNL9,VLDLR,NFIA,BNIP3L,STRADB,FERMT2,CCNG1,ASPH,CRYBG3,HERPUD1,ZNF266,PAM,GRB10,BMPR1A,TNFRSF17,CRISPLD1,CACNA2D1,PKIA |
| 9.815e-06 | -11.53 | cell surface receptor signaling pathway | biological process | GO:0007166 | 2288 | 278 | 17256 | 1658 |
CGN,ACVR1,LGR4,GRIK2,GATA3,CEBPA,STAT5B,CHAC1,PRKCA,SKI,BAG3,TGFBR3,CHRDL1,TSHR,CPE,SMAD9,ACVR1C,DCC,WLS,TGFA,LRRK2,AGO4,FGF17,ACVR2B,GPC6,NCKAP1L,WIPF3,SEMA3C,MAPK13,NRP1,UNC5B,MEF2C,EFNB2,INPPL1,CELSR1,PTPRD,ITGA6,TNFRSF10C,TNFRSF19,CHN1,FLRT3,MYC,SREBF1,TSPAN12,NCAM1,TSPAN9,GFRA1,IGSF3,BDNF,DISC1,MYO10,STAT4,VLDLR,ARID5B,CALCRL,RYR2,PLCB1,DAGLA,PELI2,WDR19,MPP2,CDH17,INHBE,SHTN1,EPHA3,BTC,AMOTL1,TCTN2,PLXNA2,IL13RA1,MAPK4,CHUK,GRK6,LCP2,DDR1,ZFYVE9,TLR3,CHRNA5,DACT1,DAB2IP,PDE4D,PERP,GAB2,FZD1,FZD4,WNT11,PRKCQ,ATOH1,PYGO1,FGFR1,ISG20,SNCA,IRS2,CXCL10,BEX3,PRKCB,APELA,HPGD,TNFSF15,GRB10,BMPR1A,MAPK10,HOXB9,MID1,EDA2R,ROBO2,FZD8,ESRP1,CD276,EPS8,GAS6,P2RY1,EPHB1,TSPAN17,ADGRB2,GHR,SMAD6,FES,VEGFC,B9D1,VAV3,PXN,ARHGEF28,RAPGEF2,GAREM1,SKAP1,GPLD1,GALNT3,PTPRC,FGR,GNAO1,MCC,GRIN2D,BMP4,TNFRSF17,FOXA1,BTRC,DDIT3,ACSL1,NDRG2,LILRB1,DNER,KREMEN1,F3,ITGB3,TBC1D32,EPHB6,TLR4,SLIT2,IL1RAP,PDGFRB,PRKACB,ITGB7,TNK2,MARK1,GCNT2,COL4A3,CR2,PLEKHA1,ROR1,BATF,TCF7L1,INHBC,TNFRSF1A,ADGRA3,OXTR,TNFSF4,MAGI2,ADGRL2,PRKAA2,RUNX2,FN1,UBASH3B,ATP6V1E2,CD7,DOK5,IL18R1,ADGRG6,DDIT4,EFEMP1,NUMBL,SEMA4F,IGF1R,LRP6,CEBPD,NOS3,FGFR4,PAK1,UNC5C,IL17RD,RHOQ,MSTN,SH2D2A,BTNL9,HOMER2,EFNA3,WWC1,BAIAP2,MAPKAPK2,GRIK4,ADGRB3,HEYL,CSF1,DISP2,SEMA3A,CXCR5,ID1,SORBS1,IL15,CELSR3,DOCK1,RBFOX2,NTRK3,CANX,PPP1R9A,SEMA6A,CD53,ADGRL1,BCL6,ACVR2A,MET,SNAI2,GLI1,FER,EVL,PTPRU,PTPN6,FGF12,CHRNA6,GSTO1,VIM,CD40,FRK,SMAD3,PTPRJ,NRG3,TRIM34,GBP1,EIF4EBP1,PTK7,ITGA2,MAOA,HGF,DISP1,LIFR,CTNND2,CNTN1,HEY1,TNIK,IL32,BMPR2,TSPAN15,LRP4,TNFSF13B,COL4A5,NOTUM,BMP6,NKX6-1,PRKCD,GTF2F2,PRICKLE2,TSPAN13,TNFRSF11A,SYK,MSX1,CRIM1,GRID1,PRICKLE1,FERMT2,LEPR,DKK1,HOMER3,CD37,FAT4,EDA,MAP2K6,GEM,IL9R |
| 9.817e-06 | -11.53 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP | 193 | 39 | 17377 | 1707 |
PLA2G4A,ACSL1,DYRK3,GPR65,KCTD12,CTBP2,TJP1,FHOD3,CA2,GATA2,TSC22D1,GSTM3,PTPRE,SMAD6,FES,CKAP4,B4GALT6,PAK1,RHOQ,GCNT2,SKAP2,MGAT4B,LITAF,DEPTOR,SHISA2,DOCK5,GABARAPL1,BCL11A,CEBPB,GSN,DOCK7,MYADM,PRCP,RAI14,RAB31,CDH17,CAB39L,LRRK1,MEF2C |
| 9.856e-06 | -11.53 | chemotaxis | biological process | GO:0006935 | 506 | 79 | 17256 | 1658 |
CXCR5,CELSR3,KIF5A,PLXNA2,GATA3,ENAH,COLEC10,NRXN1,PRKCA,DOCK2,RAC3,SEMA6A,TYMP,ITGB3,PDE4D,MET,ETV1,SLIT2,SEMA6C,PDGFRB,GAB2,NKX2-1,FER,EVL,DCC,PREX1,FEZ1,PRKCQ,ATOH1,RARRES2,IRS2,CXCL10,NRG3,PTPRJ,NCKAP1L,SEMA3C,HGF,GRB10,NRP1,UNC5B,HOXB9,EFNB2,BCL11B,ROBO2,LGALS3,CMTM8,OPHN1,KIF5C,GAS6,EPHB1,FOXG1,DOK5,NEO1,CHN1,CNTN4,SEMA4F,SCN1B,FLRT3,PRKCD,NCAM1,TNFRSF11A,GFRA1,SYK,FES,PDLIM7,TRPM4,DPYSL5,VEGFC,BDNF,UNC5C,VAV3,NR4A1,VLDLR,EFNA3,RIPOR2,MATN2,PLD1,BMP4,SEMA3A |
| 1.003e-05 | -11.51 | TMPRSS11B (transmembrane serine protease 11B) | protein interactions | 132724 | 53 | 17 | 17029 | 1718 |
TMEM67,ITPRIP,GALNT12,ITGA6,SLC7A2,NPC2,GAS6,CANX,DCBLD2,TM9SF2,SEMA4F,BACE2,MSMO1,ADGRL1,NRP1,ADGRL2,SLC16A10 |
| 1.029e-05 | -11.48 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | 265 | 49 | 17377 | 1707 |
FARP1,RHOBTB1,ST14,SEC24D,ST6GAL1,SETBP1,CBS,SCD,CHAC1,FKBP11,TXNDC5,DDIT4,EPCAM,BAG3,ZBTB38,SLC7A11,MYC,EHD3,PDE4D,SERPINH1,TSHR,ITGB7,SLC3A2,ATF4,PDK1,LRMP,DEPTOR,NFE2L1,PHACTR2,ATF3,GSTO1,SNTB1,FNDC3A,GALNT14,HERPUD1,HOMER3,ISG20,CEBPB,PTPRC,TRIB3,XBP1,SLC7A5,INHBE,FAM149A,HGF,MYOM2,MAPK13,TNFRSF17,DDIT3 |
| 1.040e-05 | -11.47 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | MSigDB lists | REACTOME_CHOLESTEROL_BIOSYNTHESIS | 21 | 10 | 17377 | 1707 |
CYP51A1,IDI1,MVK,HMGCS1,MSMO1,MVD,DHCR24,SQLE,DHCR7,HMGCR |
| 1.047e-05 | -11.47 | GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 876 | 125 | 17377 | 1707 |
ARHGAP26,BTC,RASAL2,DOCK1,GPR65,ARHGAP22,RGS20,NTRK3,DOCK3,FAM13A,DENND3,SNX9,DOCK2,TBC1D30,TIAM2,F3,TBC1D19,ARHGEF10L,ADPRHL1,SIPA1L2,PMAIP1,DAB2IP,MARCKS,PCOLCE2,HSPA2,RAPGEF5,RASGRP1,PERP,DOCK8,PDGFRB,TBC1D8,COL4A3,ACVR1C,LRRK2,PREX1,ELMOD1,WNT11,FGF17,ATP1B1,CD40,DOCK5,TBC1D16,ASPH,SERGEF,FGFR1,ARHGEF26,SNCA,SMAD3,IRS2,GSN,ARHGAP21,NCKAP1L,RASGRF2,ITGA2,ERN1,PLEKHG1,RGS10,ADRB1,ARHGAP28,BBC3,TNFSF15,TPM1,MAGI2,DENND5B,MEF2C,RGS16,LPAR2,FARP1,STXBP5L,FN1,ARHGEF11,TBC1D1,ITGA6,OPHN1,PSD3,RGS7,PFN2,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,RALGPS2,MYC,MCF2L,PRKCD,PRELID1,SRGAP1,RALGAPA2,IQGAP3,NCAM1,ERRFI1,TBC1D9,DENND1C,GFRA1,FGFR4,VAV3,RIN2,ARAP2,TBC1D8B,MCF2L2,RAPGEF2,CYTH3,RAPGEF4,ASAP3,SPATA13,RYR2,OBSCN,RASA3,HIP1,AGAP2,ARHGAP32,PLCB1,FAM162A,GPLD1,TBC1D2,DOCK7,GNAO1,ACER2,GRIN2D,IQSEC2,FNBP1L,TBC1D4,DOCK6,DOCK9 |
| 1.054e-05 | -11.46 | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_UP | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_UP | 166 | 35 | 17377 | 1707 |
LATS2,RUNX2,TTC39B,LGALS3,IL15,KIF5C,COBLL1,SLCO3A1,IL18R1,HOPX,SEMA4F,SOAT2,PIK3AP1,MARCH3,SNX10,ATP2B1,EBPL,PTPN13,LITAF,HIP1,PRDM1,DOCK5,SMPDL3B,ENTPD1,GALNT3,SMAD3,PTPRJ,MYADM,CCDC146,ERN1,PCGF2,LRRK1,BMPR1A,NRP1,ATP2B4 |
| 1.060e-05 | -11.45 | taxis | biological process | GO:0042330 | 507 | 79 | 17256 | 1658 |
CXCR5,CELSR3,KIF5A,PLXNA2,GATA3,ENAH,COLEC10,NRXN1,PRKCA,DOCK2,RAC3,SEMA6A,TYMP,ITGB3,PDE4D,MET,ETV1,SLIT2,SEMA6C,PDGFRB,GAB2,NKX2-1,FER,EVL,DCC,PREX1,FEZ1,PRKCQ,ATOH1,RARRES2,IRS2,CXCL10,NRG3,PTPRJ,NCKAP1L,SEMA3C,HGF,GRB10,NRP1,UNC5B,HOXB9,EFNB2,BCL11B,ROBO2,LGALS3,CMTM8,OPHN1,KIF5C,GAS6,EPHB1,FOXG1,DOK5,NEO1,CHN1,CNTN4,SEMA4F,SCN1B,FLRT3,PRKCD,NCAM1,TNFRSF11A,GFRA1,SYK,FES,TRPM4,PDLIM7,DPYSL5,VEGFC,BDNF,UNC5C,VAV3,NR4A1,VLDLR,EFNA3,RIPOR2,MATN2,PLD1,BMP4,SEMA3A |
| 1.063e-05 | -11.45 | BZIP | prosite domains | PS50217 | 51 | 17 | 12060 | 1278 |
CREB3L2,CEBPB,HLF,ATF4,BACH2,JDP2,XBP1,NFE2L1,MAFB,ATF3,CEBPA,DBP,CREB5,BATF,CEBPD,DDIT3,BATF3 |
| 1.110e-05 | -11.41 | GSE10325_CD4_TCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_MYELOID_DN | 187 | 38 | 17377 | 1707 |
RUSC2,MSR1,IL13RA1,CTBP2,FAM110B,DENND3,QPRT,RNF141,KMO,PRKCD,OPN3,BCL6,SCRN1,FIG4,MARCKS,TBC1D9,SNX10,COL9A2,SYK,GAB2,CYP1B1,RIN2,ALDH2,SH3BP2,RHOQ,SKAP2,TLR6,ATP10D,WARS,CEBPB,ENTPD1,GSN,FGR,PRCP,SLC2A6,RAB31,TESC,MEF2C |
| 1.110e-05 | -11.41 | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_DN | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_DN | 187 | 38 | 17377 | 1707 |
ACSL1,MRC2,BMPR2,ITPRIP,RHOBTB1,REL,CMTM8,GTF2IRD1,SNX9,DENND3,RADIL,COL27A1,SCIN,EFEMP1,TLR3,RALGPS2,SLC30A4,AKAP7,MSMO1,PRKCD,ATRNL1,PROS1,TBC1D9,FMNL2,RAPGEF5,CDH26,AGPAT4,MVD,NUAK2,ZFPM2,C3orf70,ARRDC4,SPATA9,DEXI,AHRR,HPSE,SLC7A5,FRMD5 |
| 1.110e-05 | -11.41 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | 187 | 38 | 17377 | 1707 |
ALOX5AP,STAT5B,NRXN1,DDR1,TBC1D19,RAB11FIP5,RNF141,RGS17,SYCP2,MAP1A,FRY,TSC22D1,MARCH3,ADCY6,PDE4D,DYNC2H1,SNX10,GATM,RPS23,GCA,RPL26,VAV3,MYO10,CAP2,SYBU,CR2,PRKAR2B,SATB2,LHPP,RNF44,SLC46A3,ARMC4,PTPRJ,INHBE,CLMN,TBC1D4,OCLN,PHC1 |
| 1.113e-05 | -11.41 | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | 201 | 40 | 17377 | 1707 |
TFCP2L1,MRC2,LGALS3,FN1,FGF13,ST14,ATP8A1,ESRP1,GATA3,SCD,GAS1,EPDR1,TRPS1,EPCAM,EFEMP1,FBXO32,GRHL1,ALDOC,STC2,RAB27B,PERP,PRKACB,TMEM56,FZD1,CD55,PDK1,FAM84A,SLC39A8,MAFB,WWC1,DSP,GABARAPL1,GSN,PLK2,BMP1,DBP,HK1,LRRK1,FOXA1,ATP1A3 |
| 1.114e-05 | -11.40 | regulation of cell morphogenesis involved in differentiation | biological process | GO:0010769 | 279 | 50 | 17256 | 1658 |
UST,TNIK,DNM3,ID1,ZSWIM5,FN1,FGF13,BMPR2,ROBO2,PTPRD,DOCK1,LRP4,PLXNA2,HECW2,NTRK3,RAC3,PPP1R9A,NEDD4,ARHGAP44,NKX6-1,RND2,CHN1,SEMA4F,RAP2A,CTTN,SLIT2,PAK1,BDNF,SSH3,LZTS3,DCC,RAPGEF2,LRRK2,PREX1,AMIGO1,DOCK5,BAIAP2,MAP1B,MYADM,ADGRB3,MAP2,GBP1,PTPRS,SEMA3C,NRP1,SPART,SHOX2,SEMA3A,CDH2,SHTN1 |
| 1.133e-05 | -11.39 | GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP | 153 | 33 | 17377 | 1707 |
ACSL1,HERC5,SLC7A2,SLCO3A1,CCNJ,ATXN7L1,FLRT3,PRELID2,EIF1,BNIP3,SLC6A15,ERRFI1,MET,SNX10,PTPRE,RASGRP1,DUSP1,TES,LRRK2,CALCRL,ATF3,ATOH1,RAB38,CD40,BATF,CXCL10,KPNA3,MYADM,EIF4EBP1,PPARGC1A,CMPK2,SLFN5,FNBP1L |
| 1.135e-05 | -11.39 | ductolobular_carcinoma | COSMIC cancer mutations | ductolobular_carcinoma | 1650 | 212 | 17385 | 1698 |
FAM171B,THOC5,FGF13,GRIK2,HEBP1,UGDH,FHDC1,PPFIBP2,GATA3,LILRB1,FAM102B,NPM1,NDRG2,CEBPA,FSTL5,EYA4,PLS3,ARHGEF10L,PPM1E,EOMES,ABI3BP,SLC16A2,ANKFN1,ITGB3,COL19A1,JAKMIP2,TMEM37,COG3,TLN2,CPE,OR2W3,TSHR,NEB,RASGRP1,DBN1,KCNIP3,DCC,SPOCD1,ANK2,DSTN,DNAJC6,TNS1,KCND3,ROR1,TCERG1L,EML1,AHRR,TMEM132B,GSN,TCF7L1,SH3RF1,MAP2,RASGRF2,BMP1,MAPK13,DSEL,SPOCK3,MEF2C,BCL11B,PRKAA2,FN1,PTPRD,ZNF25,ZCCHC24,SETBP1,SPINK5,CHD5,FHOD3,ABLIM1,FRY,CNTN4,PDZD7,GATA2,FRAS1,CACNB2,FAM107B,SMTN,DENND1C,FIGN,FBXL2,RIMS2,NOS3,KCNQ3,PLEKHA8,COL4A4,PARD3B,STAT4,HOMER2,RAPGEF4,TMTC4,RYR2,WWC1,OBSCN,TTYH2,PEX5L,PRDM1,SDK1,PLCB1,DHX32,MMP15,INHBE,PTPRN2,IQSEC2,SEMA3A,AMPD1,CXCR5,EPHA3,PLA2G4A,AVPI1,SORBS1,RASAL2,DOCK1,MYO1B,NTRK3,FAM110B,RADIL,PIBF1,CYP26A1,ZSCAN5A,TBC1D19,CDS1,ZNF438,UNC13B,TACC2,DACT1,ALDH1L1,ZNF521,NBEA,PROS1,MET,SCN2A,DNAH5,NTNG1,KCNB2,SCN3A,IGFBP3,GLI1,SUSD3,DPP10,MYLK3,EVL,FZD4,PTPRU,PTPN6,PRDM13,NLGN4X,VIM,AMIGO1,RAB38,FGFR1,BCL11A,ZNF569,WARS,SMAD3,IRS2,PTPRS,MAOA,KLF5,ATG5,NR3C2,LIFR,PURG,CTNND2,CNTN1,MYO1D,FARP1,BMPR2,ROBO2,APBB1,NLRP14,CLSTN2,GPR180,PKN1,EPHB1,KCNC4,BMP6,NEDD4,SLC35F1,FOXP2,MAP1A,DSG2,SGK3,TRIM3,AFAP1L2,MED12L,PDLIM7,MN1,PFKFB4,VAV3,MCF2L2,GRID1,ASAP3,PRRG1,AGAP2,ATP11A,GUCY1A2,ZFPM2,MAP1B,CTIF,PTPRC,OR2T33,MFSD9,EDA,TERT,XBP1,OSBPL5,KIAA0513,GRIN2D,SLC22A15,DDIT3,PHC1,ZNF235 |
| 1.135e-05 | -11.39 | breast-carcinoma-ductolobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductolobular_carcinoma | 1650 | 212 | 17385 | 1698 |
FAM171B,THOC5,FGF13,GRIK2,HEBP1,UGDH,FHDC1,PPFIBP2,GATA3,LILRB1,FAM102B,NPM1,NDRG2,CEBPA,FSTL5,EYA4,PLS3,ARHGEF10L,PPM1E,EOMES,ABI3BP,SLC16A2,ANKFN1,ITGB3,COL19A1,JAKMIP2,TMEM37,COG3,TLN2,CPE,OR2W3,TSHR,NEB,RASGRP1,DBN1,KCNIP3,DCC,SPOCD1,ANK2,DSTN,DNAJC6,TNS1,KCND3,ROR1,TCERG1L,EML1,AHRR,TMEM132B,GSN,TCF7L1,SH3RF1,MAP2,RASGRF2,BMP1,MAPK13,DSEL,SPOCK3,MEF2C,BCL11B,PRKAA2,FN1,PTPRD,ZNF25,ZCCHC24,SETBP1,SPINK5,CHD5,FHOD3,ABLIM1,FRY,CNTN4,PDZD7,GATA2,FRAS1,CACNB2,FAM107B,SMTN,DENND1C,FIGN,FBXL2,RIMS2,NOS3,KCNQ3,PLEKHA8,COL4A4,PARD3B,STAT4,HOMER2,RAPGEF4,TMTC4,RYR2,WWC1,OBSCN,TTYH2,PEX5L,PRDM1,SDK1,PLCB1,DHX32,MMP15,INHBE,PTPRN2,IQSEC2,SEMA3A,AMPD1,CXCR5,EPHA3,PLA2G4A,AVPI1,SORBS1,RASAL2,DOCK1,MYO1B,NTRK3,FAM110B,RADIL,PIBF1,CYP26A1,ZSCAN5A,TBC1D19,CDS1,ZNF438,UNC13B,TACC2,DACT1,ALDH1L1,ZNF521,NBEA,PROS1,MET,SCN2A,DNAH5,NTNG1,KCNB2,SCN3A,IGFBP3,GLI1,SUSD3,DPP10,MYLK3,EVL,FZD4,PTPRU,PTPN6,PRDM13,NLGN4X,VIM,AMIGO1,RAB38,FGFR1,BCL11A,ZNF569,WARS,SMAD3,IRS2,PTPRS,MAOA,KLF5,ATG5,NR3C2,LIFR,PURG,CTNND2,CNTN1,MYO1D,FARP1,BMPR2,ROBO2,APBB1,NLRP14,CLSTN2,GPR180,PKN1,EPHB1,KCNC4,BMP6,NEDD4,SLC35F1,FOXP2,MAP1A,DSG2,SGK3,TRIM3,AFAP1L2,MED12L,PDLIM7,MN1,PFKFB4,VAV3,MCF2L2,GRID1,ASAP3,PRRG1,AGAP2,ATP11A,GUCY1A2,ZFPM2,MAP1B,CTIF,PTPRC,OR2T33,MFSD9,EDA,TERT,XBP1,OSBPL5,KIAA0513,GRIN2D,SLC22A15,DDIT3,PHC1,ZNF235 |
| 1.170e-05 | -11.36 | NEDD4 (neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase) | protein interactions | 4734 | 303 | 55 | 17029 | 1718 |
LATS2,SCN5A,TNIK,ANKRD13D,AMOTL1,SCN8A,RASL11B,NHP2,NDFIP2,TNFRSF19,STK24,NEDD4,DDIT4,IGF1R,KCNAB1,RAP2A,SGK1,PRKG2,ERRFI1,SMAD6,PRR16,SPRY2,SYK,PDGFRB,SP140L,FES,PDLIM7,TNK2,RAPGEF2,FGF12,LITAF,PRRG1,TTYH2,SAV1,SGK2,FGFR1,BAIAP2,GABARAPL1,SNCA,SMAD3,IRS2,PMEPA1,MAP2,AKT3,PLK2,LAPTM4B,GRIN2D,GRB10,BMPR1A,LRRK1,JHY,BTRC,SHTN1,OCLN,ABCG1 |
| 1.179e-05 | -11.35 | ACTGTGA,MIR-27A,MIR-27B | MSigDB lists | ACTGTGA,MIR-27A,MIR-27B | 442 | 72 | 17377 | 1707 |
ACVR1,ST14,RNF144A,ENAH,NRXN1,FAM13A,NOVA1,SEMA6A,EYA4,CCNJ,CDS1,ZNF827,PPM1E,EEPD1,ACVR2A,MARCKS,MYT1,MEIS2,KLHL4,ANK2,PANK1,SATB2,KPNA3,SH3RF1,PLK2,RBPMS2,NCOA7,DIRAS1,APBA2,LIFR,LONRF1,GNG12,PLAG1,ZCCHC24,PGAP1,NEDD4,NEO1,FOXP2,SLC35F1,SLC7A11,GATA2,FLRT3,CACNB2,EHD3,ADCY6,PRICKLE2,SEPT3,SPRY2,ATP2B1,ZNF385A,MOB1B,VAV3,AGPAT4,FOXN3,LITAF,EDEM3,HIP1,ST6GALNAC3,SNAP25,CCNG1,ARRDC4,MBNL2,GALNT3,PLEKHH2,RND3,CSF1,MFSD2A,C1orf21,PGM2L1,SLCO5A1,SH3BGRL2,PKIA |
| 1.189e-05 | -11.34 | Kinase-like_dom_sf | interpro domains | IPR011009 | 523 | 82 | 18492 | 1811 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PDGFRB,PRKACB,FER,TNK2,MYLK3,MARK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,GRK3,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAP3K21,MAPK13,PIK3C2B,BMPR1A,MAPK10,MAST1,TYRO3,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FES,FGFR4,PAK1,HYKK,NUAK2,OBSCN,STRADB,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,MAP2K6,AKT3,NEK11,LRRK1,MAP3K20 |
| 1.206e-05 | -11.33 | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF | 466 | 75 | 17377 | 1707 |
PHACTR3,AVPI1,ID1,TRIM16,LDLR,C20orf194,RHPN2,ADAMTS6,CTBP2,GRK6,KIAA1217,SLC19A2,PCDH7,SIPA1L2,PMAIP1,POU5F1B,MET,RCAN3,PTPRE,ZNF365,RAPGEF5,SNAI2,TBC1D8,ATL1,TGFA,MFSD6,DOCK5,SMAD3,IRS2,DYRK1B,ARHGAP21,GPRC5B,RNF217,SH3RF1,ENTPD7,GBP1,CCNA1,DLX2,OXTR,SPRY4,NRP1,EFNB2,ENO2,ARL15,SLK,RUSC2,ATP9A,ELOVL7,BBS9,PHLDA2,NEDD4,DDIT4,RASSF8,NUMBL,MYC,SRGAP1,TSC22D1,SGK1,ZFP36L2,SPRY2,VEGFC,ARAP2,CRIM1,ARID5B,SYBU,FHL2,PALLD,TBC1D2,CLDN12,MATN2,KIAA0513,TUFT1,PGM2L1,TMEM117,FNBP1L |
| 1.210e-05 | -11.32 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_DN | 167 | 35 | 17377 | 1707 |
FAM171B,RGS16,FGF13,TNFSF13B,GTF2IRD1,COL4A5,SNX9,DDIT4,BAG3,TYMP,GPR155,FAM107B,BCL6,SGK1,ALPK1,IPCEF1,MYO6,MAST4,VAV3,SLC27A2,RAPGEF2,EFHC2,ATP1B1,ZDHHC14,EXOG,PALLD,ARMC4,ATPAF2,BACH2,ANKRD31,THSD7B,SRD5A3,CCNA1,EGFL7,BMPR1A |
| 1.215e-05 | -11.32 | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | 66 | 19 | 17377 | 1707 |
SLC3A2,AVPI1,ATF4,PDK1,NR4A1,LDLR,ATF3,PRDM1,F12,CANX,BMP6,FKBP11,TXNDC5,TERT,PAM,TUFT1,TNFRSF17,DDIT3,AMPD1 |
| 1.215e-05 | -11.32 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | 66 | 19 | 17377 | 1707 |
TFCP2L1,NBL1,NR4A1,ITPR2,LEPR,IRS2,CEBPB,MSC,ID3,IGF1R,CFHR1,BCL6,LRP6,BMP4,KLF9,HSPA2,DDIT3,DUSP1,IGFBP3 |
| 1.235e-05 | -11.30 | small molecule biosynthetic process | biological process | GO:0044283 | 575 | 87 | 17256 | 1658 |
PLA2G4A,NUDT10,MVK,ADAL,PDE1B,ELOVL4,AASS,UGDH,ASS1,ABAT,BCAN,NUDT12,CYP51A1,TYMP,IDI1,ASNS,ERG28,KMO,ALDOC,PDE4D,PLTP,ENO1,GATM,CTH,ATF4,GAPDH,UROS,PFKFB2,MVD,HACD1,ATF3,PYCR1,ENPP1,INSIG1,ALDOA,BDH2,HPGD,DSEL,PPARGC1A,PSPH,PRKAA2,UST,GPT2,SERINC5,ALOX5AP,ENO2,RIMKLA,ELOVL7,DHCR24,OLAH,CBS,SCD,ISYNA1,SLC1A3,PHGDH,PRTFDC1,HMGCS1,MSMO1,PDE10A,PCK2,MOXD1,SYK,SMPDL3A,HMGCR,FADS1,ATP5IF1,PNP,SLC27A2,MGST3,ELOVL3,FASN,OGDHL,PDE8A,RIMKLB,PLOD2,ACER2,SRD5A3,XBP1,HK2,PGM2L1,SQLE,HK1,DHCR7,PTGES,OSBPL6,ACSM3,NUDT17 |
| 1.252e-05 | -11.29 | GSE22886_NEUTROPHIL_VS_DC_UP | MSigDB lists | GSE22886_NEUTROPHIL_VS_DC_UP | 181 | 37 | 17377 | 1707 |
BTC,NECAB2,CELSR1,MCTP2,SELL,HERC5,TNFRSF10C,GPSM2,EPHB1,HOPX,LGI2,RNF141,RAB11FIP5,FUT9,AFF2,LHX6,ALDH1L1,ZNF460,ETV1,SLIT2,RIMS2,CEBPD,DUSP1,GCA,VNN2,RAB6B,NR6A1,EFHC2,OGDHL,ISG20,GPLD1,TUFT1,RNF122,TTC39A,IL9R,FOXA1,HEY1 |
| 1.255e-05 | -11.29 | postsynaptic density | cellular component | GO:0014069 | 224 | 42 | 18223 | 1724 |
DNM3,CACNG3,BMPR2,GRIK2,LRP4,CLSTN2,PSD3,ADD2,P2RY1,PCLO,PPP1R9A,CTNNA2,ARHGAP44,NCS1,EPB41L3,LIN7A,MPDZ,BNIP3,DLGAP1,DISC1,LZTS3,CAP2,SHANK2,HOMER2,DNAJC6,GRID1,NLGN4X,ARHGAP32,CPEB1,BAIAP2,MAP1B,HOMER3,CAMK2N1,GRIK4,MAP2,MPP2,PTPRS,DLG2,GRIN2D,MAGI2,CDH2,LZTS1 |
| 1.261e-05 | -11.28 | V$HFH8_01 | MSigDB lists | V$HFH8_01 | 188 | 38 | 17377 | 1707 |
BCL11B,C1QTNF3,SCAMP1,KCTD12,RASD1,NTRK3,CREB5,LCP2,NOVA1,TSPAN17,HMCN1,BEX2,NEDD4,FOXP2,KCTD15,FLRT3,SLC10A7,MARCKS,PPP2R2B,ETV1,GFRA1,DUSP1,DPP10,SSH3,NR6A1,NR4A1,FOXN3,SLC39A8,ESRRG,FHL2,CLN5,PDLIM3,KLF12,PELI2,KIF21A,PPARGC1A,MAPK10,HOXB9 |
| 1.261e-05 | -11.28 | GSE7852_THYMUS_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_THYMUS_VS_FAT_TCONV_DN | 188 | 38 | 17377 | 1707 |
CREB3L2,EFNB2,LATS2,INPPL1,FARP1,DYRK3,RUNX2,SEC24D,RNF144A,REL,LDLR,KIF5C,DOCK2,IL18R1,HOPX,PLS3,TRPS1,RAB11FIP5,ATXN7L1,RUNDC3B,TSC22D1,PROS1,ANTXR2,PNP,RAB6B,CRIM1,AGPAT4,LITAF,NUAK2,HIP1,ATF3,ENPP1,ARHGAP21,MYADM,KLF12,EIF4EBP1,SQLE,ATP2B4 |
| 1.263e-05 | -11.28 | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_UP | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_UP | 195 | 39 | 17377 | 1707 |
DYRK3,IL15,RHOBTB1,DOCK1,NRN1,HBE1,TBC1D30,MCU,DDIT4,IDI1,CA2,SEMA4F,BACE2,ITGB3,RALGAPA2,LRP6,TOX,SPRY2,NEB,ZFP36L2,CKAP4,SNAI2,MED12L,FADS1,KLHL23,FAM84A,SLC39A8,GDPD1,C3orf52,DEPTOR,TEX9,SFXN1,GALNT3,TMCO3,SVIL,ARHGAP28,BMPR1A,CDH2,LPP |
| 1.308e-05 | -11.24 | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN | MSigDB lists | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN | 154 | 33 | 17377 | 1707 |
RUNX2,FOXG1,SATB1,FSTL5,CD53,RTN1,RND2,EOMES,LRRN1,MPPED2,SGK3,SCRN1,JAKMIP2,KIAA0408,MYT1,JAM2,RAPGEF5,GFRA1,TMEM56,PARP9,PAK1,GDAP1,SPATA6,BCL11A,INSIG1,MAP2,HPGD,PGM2L1,KIF21A,SHOX2,MAPK10,FRMD5,PKIA |
| 1.334e-05 | -11.22 | FN3_sf | interpro domains | IPR036116 | 203 | 40 | 18492 | 1811 |
EPHA3,TYRO3,LRFN5,FN1,ROBO2,PTPRD,IL13RA1,EPHB1,COL14A1,F3,NEO1,FSD1,SPEG,CNTN4,LRRN1,IGF1R,ABI3BP,FLRT3,ANKFN1,GHR,EPHB6,NCAM1,FANK1,MID2,PTPRU,DCC,OBSCN,SDK1,FNDC3A,LEPR,TRIM9,PTPRC,PTPRJ,NCAM2,PTPRS,MYOM2,IL9R,LIFR,MID1,CNTN1 |
| 1.351e-05 | -11.21 | vasculature development | biological process | GO:0001944 | 494 | 77 | 17256 | 1658 |
AMOTL1,ACVR1,ID1,RECK,ARHGAP22,COL18A1,ADAMTS6,PRKCA,TYMP,TGFBR3,ITGB3,DAB2IP,SLIT2,PDGFRB,CYP1B1,CEMIP2,ADM2,FZD4,YAP1,WNT11,ACVR2B,JAM3,FGFR1,WARS,GJC1,HPSE,CCBE1,PTK7,APELA,HPGD,KLF5,SEMA3C,BMPR1A,UNC5B,NRP1,VASH2,HEY1,PCSK5,MEF2C,EFNB2,BMPR2,FN1,FZD8,SLC12A6,OVOL2,EPHB1,ACTA2,TSPAN12,DYNC2H1,LOXL4,ERRFI1,SMAD6,SYK,NOS3,VEGFC,B9D1,FGFR4,VAV3,ATP5IF1,SH2D2A,NR4A1,RAPGEF2,PRICKLE1,CALCRL,PRDM1,ZFPM2,LEPR,HOXA1,GPLD1,HEG1,PRCP,XBP1,EGFL7,BMP4,CDH2,DHCR7,DDIT3 |
| 1.355e-05 | -11.21 | BHAT_ESR1_TARGETS_VIA_AKT1_DN | MSigDB lists | BHAT_ESR1_TARGETS_VIA_AKT1_DN | 78 | 21 | 17377 | 1707 |
CREB3L2,EFNB2,CGN,ARID5B,PTPN21,EPS8,YPEL2,GTF2IRD1,PSD3,ATP1B1,SPATA7,MKX,GRHL1,LAMB1,KIAA0513,AFAP1L2,FAM84B,DBP,KLF9,NRP1,IGSF3 |
| 1.358e-05 | -11.21 | I-set | pfam domains | PF07679 | 135 | 30 | 17054 | 1666 |
FGFR4,TYRO3,UNC5C,LRFN5,ROBO2,PTPRD,DCC,OBSCN,NTRK3,AMIGO1,SDK1,ROR1,PALLD,HMCN1,FGFR1,NEGR1,NEO1,SPEG,CNTN4,LRRN1,NCAM2,PTK7,PTPRS,SEMA3C,MYOM2,ADGRA3,NCAM1,UNC5B,PDGFRB,CNTN1 |
| 1.358e-05 | -11.21 | fn3 | pfam domains | PF00041 | 135 | 30 | 17054 | 1666 |
TYRO3,EPHA3,MID2,FN1,ROBO2,PTPRU,PTPRD,DCC,OBSCN,SDK1,FNDC3A,EPHB1,COL14A1,NEO1,FSD1,PTPRC,TRIM9,PTPRJ,CNTN4,NCAM2,ABI3BP,GHR,ANKFN1,PTPRS,MYOM2,EPHB6,NCAM1,LIFR,MID1,CNTN1 |
| 1.361e-05 | -11.20 | V$EVI1_04 | MSigDB lists | V$EVI1_04 | 224 | 43 | 17377 | 1707 |
BCL11B,TYRO3,NMNAT3,NEK10,TCP11L2,BMPR2,FGF13,CHCHD7,PLAG1,MORC4,ADAMTS6,CHAC1,IKZF2,SEMA6A,NEDD4,MTUS1,FOXP2,SAMD11,CHRDL1,MYO3B,BEND4,RTKN2,PDE4D,TMEM56,PTCH2,SLC40A1,BDNF,MEIS2,FGF12,PRDM1,ATOH1,RERE,ZIC1,BCL11A,EBF1,NCAM2,KIAA0355,KLF5,DLG2,TNFSF4,TPM1,PPARGC1A,MID1 |
| 1.361e-05 | -11.20 | V$SOX9_B1 | MSigDB lists | V$SOX9_B1 | 224 | 43 | 17377 | 1707 |
BCL11B,FN1,RHOBTB1,KLHL13,RBFOX2,SCD,ZIC2,APBA1,PFN2,NEO1,CCNJ,NAV1,KCNN2,LRRN1,FLRT3,LHX6,ACVR2A,EPHB6,MARCKS,PPP2R2B,NCAM1,FANK1,ETV1,MYT1,SLIT2,SEMA6C,KCNB2,DPYSL5,PAK1,PNRC1,NR4A1,VLDLR,SKAP1,FGFR1,RERE,ZIC1,EBF1,SLC39A14,ZNF711,PELI2,GNAO1,C1orf21,PHC1 |
| 1.378e-05 | -11.19 | skin-trunk-malignant_melanoma-nodular | COSMIC cancer mutations | skin-trunk-malignant_melanoma-nodular | 1314 | 174 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,CGN,THOC5,GRIK2,ATP8A1,LDLR,FHDC1,TNFAIP8L2,GATA3,ADAMTS6,ABAT,SNX9,CA8,HMCN1,NCS1,ARHGEF10L,LGI2,BAG3,LRRC6,KCNS3,GSTM3,COL19A1,COG3,TLN2,VWA5A,MYRIP,CPE,OR2W3,TLR4,TSHR,IL1RAP,DCC,CAP2,CR2,TCERG1L,EML1,SFXN1,DYRK1B,NCKAP1L,TECPR2,CCDC146,BMP1,ARHGAP28,MAPK13,UNC5B,SPOCK3,LZTS1,PCSK5,SV2B,LRFN5,CELSR1,SEC24D,OPHN1,SETBP1,LRRC49,TNFRSF10C,CD7,BBS9,MECOM,ABLIM1,GBGT1,CNTN4,APLF,PDE10A,HS3ST5,SMTN,CPXM2,LIMCH1,SLCO4C1,MOXD1,CHRM3,NOS3,CDH26,DISC1,PLS1,SNAP25,SDK1,CDC42BPA,PLCB1,KHDRBS2,STEAP1,BAIAP2,BEX4,TEX15,KIAA0355,MFSD2A,EMILIN2,CDH17,PTPRN2,PLD1,DHCR7,EPHA3,GALNT12,BEGAIN,COBLL1,NTRK3,KIF21B,DENND3,COL14A1,DOCK2,ZSCAN5A,ZNF827,COL22A1,UNC13B,GPRIN1,TACC2,ZDHHC6,EEPD1,DNAH5,MYT1,DOCK8,KCNB2,PRAME,MYLK3,KCNH5,ADCY1,PRKCQ,CD40,DOCK5,ZNF711,IQCH,RNF217,GBP1,PTPRS,SOHLH2,PLD5,CTNND2,OR51B5,ANO10,WASF3,PCDH18,WDR17,SLC6A9,GCAT,GRB14,KLHL13,APBB1,MCTP2,GABRG2,SLC12A6,USP30,RGS7,NEO1,LRRC55,SGK1,DHRS12,SYK,RBMS2,ATP2B1,MICAL2,ARAP2,CLYBL,LRRIQ1,ESRRG,FOXN3,PALLD,MGMT,MAP1B,EBF1,PTPRC,NSD1,CD37,PCDHB7,FAT4,MPP7,FBN1,SLC7A5,MYOM2,KIF21A,OCLN,SLC43A1,ZNF235 |
| 1.400e-05 | -11.18 | cardiac chamber morphogenesis | biological process | GO:0003206 | 124 | 28 | 17256 | 1658 |
ACVR1,BMPR2,FHL2,GATA3,PKP2,RYR2,SMARCD3,NSD2,WNT11,OVOL2,ZFPM2,SAV1,DSP,ADGRG6,HEG1,TGFBR3,HEYL,SEMA3C,BMPR1A,BMP4,TPM1,NRP1,SMAD6,CPE,SHOX2,HEY1,FZD1,MEF2C |
| 1.405e-05 | -11.17 | testis | COSMIC cancer mutations | testis | 742 | 108 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,PLXNA2,RHPN2,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,TRPS1,RTN1,BAG3,SPEG,PPM1E,RPS6KA2,COL25A1,RPS6KL1,MYO3B,ACVR2A,MET,NEB,PRKACB,PDGFRB,FER,TNK2,MYLK3,ERGIC1,MARK1,PDK1,ACVR1C,ANK2,ALDH1L2,LRRK2,ZNF565,PRKCQ,PRKAR2B,ROR1,ACVR2B,SGK2,TBC1D16,FRK,FGFR1,ZNF569,DYRK1B,PRKCB,PLK2,PTK7,ERN1,BMP1,MAPK13,BMPR1A,MAST1,PRKAA2,TNIK,LATS2,DYRK3,INPPL1,BMPR2,SEC24D,UBAC2,SETBP1,ISYNA1,PKN1,EPHB1,IGF1R,ADCK1,PDE10A,PRKCD,SGK3,PRKG1,RALGAPA2,SGK1,ALPK1,SYK,FES,MED12L,NOS3,PAK1,FGFR4,PCDH10,PTPN13,DCHS1,NUAK2,OBSCN,STRADB,CDC42BPA,NAALADL2,MAPKAPK2,KCNK15,TRIB3,FGR,TMEM237,TERT,PKN3,PRCP,AKT3,MAP2K6,OSBPL5,SRD5A3,CDH17,MCC,NEK11,KIF1B,FILIP1,LARP1,CACNA2D1 |
| 1.412e-05 | -11.17 | ONKEN_UVEAL_MELANOMA_DN | MSigDB lists | ONKEN_UVEAL_MELANOMA_DN | 500 | 79 | 17377 | 1707 |
SORBS1,SCAMP1,VAMP8,LMCD1,COBLL1,NPM1,ABHD6,PCLO,SEMA6A,TUBB4A,ALDH1L1,KCNS3,MPPED2,GSTM3,PCOLCE2,MARCKS,PDE4D,VWA5A,ETV1,TLR4,HSPA2,PRKACB,CTH,HRASLS,GCA,TDRD3,DSTN,NFE2L1,TMEM47,JAM3,NT5DC2,SNCA,GABARAPL1,GNAI1,ENTPD1,GYPC,KLF5,ZBTB20,SERPINI1,DBP,RRAGD,PLSCR4,MLF1,IPO5,ARL2,PSD3,TJP1,SATB1,GAS1,MTUS1,ABLIM1,RSL24D1,ZBTB38,KIAA0895,TFAP2A,ADCY6,SLC6A15,CADPS2,DYNC2H1,SPRY2,GPR161,CAND2,MID2,GSTM2,KDM5B,RAB6B,SYBU,FHL2,ATP11A,PALLD,MBNL2,C4orf19,GLCE,GPR37,BEX4,RPL28,PLOD2,PRCP,MATN2 |
| 1.425e-05 | -11.16 | PEREZ_TP53_AND_TP63_TARGETS | MSigDB lists | PEREZ_TP53_AND_TP63_TARGETS | 182 | 37 | 17377 | 1707 |
GPT2,SERINC5,COL9A3,STOX2,FGF13,ZCCHC24,BIK,COL18A1,ZIC2,ABHD6,PGAP1,COL27A1,EPB41L3,SIPA1L2,IGF1R,FRY,CNKSR3,REEP1,MARCH3,TOX,MOXD1,SMAD6,SLIT2,RASGRP1,ZNF385A,IGFBP3,FZD1,SMAD9,ELMOD1,SPATA13,ADCY1,MAFB,GPR37,PTPRJ,TUFT1,UNC5B,PCSK5 |
| 1.425e-05 | -11.16 | LEF1_UP.V1_UP | MSigDB lists | LEF1_UP.V1_UP | 182 | 37 | 17377 | 1707 |
PRKAA2,WASF3,COL9A3,SCN5A,PCSK1N,FN1,IGFBP6,FGF13,GATA3,CBS,KCTD12,ISYNA1,FOXG1,CHST10,NELL2,STC2,WWC2,DENND1C,PLTP,CTH,DBN1,FADS1,SH2D2A,DNAJC6,VIM,TMEM47,ZFPM2,MAP1B,DKK1,PMEPA1,PELI2,KCNG1,INHBE,PTPRN2,MAOA,PCSK5,RRAGD |
| 1.425e-05 | -11.16 | GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN | 182 | 37 | 17377 | 1707 |
PRKAA2,PLSCR4,ENO2,UBASH3B,CCDC120,RND2,FRY,CDC14B,ALDOC,ALDH1L1,GHR,PRKG1,NBEA,CADPS2,NAP1L3,SLC16A9,CERS4,EPHB6,RBMS2,MED12L,SFXN4,EXOC6B,VLDLR,RAB38,PALLD,TTC28,TTLL7,LDHD,ATP10D,ENTPD1,TRIB3,PLXDC2,RAI14,DLG2,PPARGC1A,CRISPLD1,PHC1 |
| 1.433e-05 | -11.15 | HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN | MSigDB lists | HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN | 45 | 15 | 17377 | 1707 |
TRIB3,MSX1,SH3GL2,FRAS1,LITAF,PAM,ASS1,RHPN2,GSTO1,FAM84B,PCK2,SNTB1,TESC,MGMT,CEBPD |
| 1.433e-05 | -11.15 | ZHAN_MULTIPLE_MYELOMA_CD2_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD2_DN | 45 | 15 | 17377 | 1707 |
GPR37,LATS2,TDO2,PFKFB2,GJB2,C1orf53,HK2,MCC,FASN,NFIA,PRICKLE2,MSRB3,CR2,NEDD4,RRAGD |
| 1.435e-05 | -11.15 | cardiovascular system development | biological process | GO:0072358 | 503 | 78 | 17256 | 1658 |
AMOTL1,ACVR1,ID1,RECK,ARHGAP22,COL18A1,ADAMTS6,PRKCA,TYMP,TGFBR3,ITGB3,DAB2IP,SLIT2,PDGFRB,CYP1B1,CEMIP2,ADM2,FZD4,YAP1,WNT11,ACVR2B,JAM3,FGFR1,WARS,GJC1,HPSE,CCBE1,PTK7,APELA,HPGD,KLF5,SEMA3C,BMPR1A,UNC5B,NRP1,VASH2,HEY1,PCSK5,MEF2C,EFNB2,BMPR2,FN1,FZD8,SLC12A6,OVOL2,EPHB1,ACTA2,TSPAN12,DYNC2H1,LOXL4,ERRFI1,SMAD6,SYK,NOS3,VEGFC,B9D1,FGFR4,VAV3,ATP5IF1,SH2D2A,NR4A1,RAPGEF2,SLITRK5,PRICKLE1,CALCRL,PRDM1,ZFPM2,LEPR,HOXA1,GPLD1,HEG1,PRCP,XBP1,EGFL7,BMP4,CDH2,DHCR7,DDIT3 |
| 1.436e-05 | -11.15 | Ig_I-set | interpro domains | IPR013098 | 135 | 30 | 18492 | 1811 |
FGFR4,TYRO3,LRFN5,UNC5C,ROBO2,PTPRD,DCC,OBSCN,NTRK3,AMIGO1,ROR1,SDK1,PALLD,HMCN1,FGFR1,NEGR1,NEO1,SPEG,CNTN4,LRRN1,NCAM2,PTK7,PTPRS,MYOM2,SEMA3C,ADGRA3,UNC5B,NCAM1,PDGFRB,CNTN1 |
| 1.446e-05 | -11.14 | stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable | COSMIC cancer mutations | stomach-carcinoma-mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable | 973 | 135 | 17385 | 1698 |
CGN,TRIM2,FGF13,NPM1,CTBP2,ITPR2,PLS3,EOMES,ABI3BP,PPFIA2,CFHR1,KCNS3,TLR4,MARK1,ANK2,JPH1,TMEM200C,TMEM47,INTS6,TMEM132B,GPRC5B,WIPF3,ITGBL1,MAP2,NCAM2,P4HA2,GNB4,ATP7B,TECPR2,OXTR,DNHD1,MAGI2,TMEM63C,LATS2,PTPRD,LAMC3,DYNC1I1,PRTFDC1,IGF1R,KIAA1257,FRAS1,GRIP1,CADPS2,FIGN,MOXD1,COL9A2,RIMS2,CHRM3,HMGCR,GPR176,SLITRK2,ARID5B,RAPGEF4,PACSIN3,OBSCN,SDK1,SLC46A3,TBC1D2,TEX15,FCHO2,FAT1,THBS4,CLMN,SMYD3,OTX1,HECW2,COBLL1,NTRK3,SLC7A2,KIF21B,LCP2,COL14A1,PCLO,DOCK2,TIAM2,SCIN,SPEG,EPB41L3,PDZD8,EEPD1,ZNF521,ACVR2A,NBEA,MYT1,DNAH5,DPP10,INTU,COL6A2,LRRC8B,ADCY1,PREX1,FGF12,WNT11,SATB2,BACH2,PRKCB,PEMT,KCNG1,ITGA2,CNTN1,ANKRD13D,ROBO2,CKAP2,KIF5C,USP30,SFXN3,EPHB1,BEX2,LRRN1,PRICKLE2,CCDC122,SLC6A15,KLF9,MYO6,FES,MN1,RIN2,ARHGEF28,LRRIQ1,MCF2L2,CACNA1E,SNTB1,ZFPM2,GPR37,DPY19L2,ADAMTS17,TRIB3,PLPPR2,FBN1,SLCO5A1,DOCK6,CACNA2D1,ATP2B4,ABCG1,TLL2 |
| 1.446e-05 | -11.14 | mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable | COSMIC cancer mutations | mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable | 973 | 135 | 17385 | 1698 |
CGN,TRIM2,FGF13,NPM1,CTBP2,ITPR2,PLS3,EOMES,ABI3BP,PPFIA2,CFHR1,KCNS3,TLR4,MARK1,ANK2,JPH1,TMEM200C,TMEM47,INTS6,TMEM132B,GPRC5B,WIPF3,ITGBL1,MAP2,NCAM2,P4HA2,GNB4,ATP7B,TECPR2,OXTR,DNHD1,MAGI2,TMEM63C,LATS2,PTPRD,LAMC3,DYNC1I1,PRTFDC1,IGF1R,KIAA1257,FRAS1,GRIP1,CADPS2,FIGN,MOXD1,COL9A2,RIMS2,CHRM3,HMGCR,GPR176,SLITRK2,ARID5B,RAPGEF4,PACSIN3,OBSCN,SDK1,SLC46A3,TBC1D2,TEX15,FCHO2,FAT1,THBS4,CLMN,SMYD3,OTX1,HECW2,COBLL1,NTRK3,SLC7A2,KIF21B,LCP2,COL14A1,PCLO,DOCK2,TIAM2,SCIN,SPEG,EPB41L3,PDZD8,EEPD1,ZNF521,ACVR2A,NBEA,MYT1,DNAH5,DPP10,INTU,COL6A2,LRRC8B,ADCY1,PREX1,FGF12,WNT11,SATB2,BACH2,PRKCB,PEMT,KCNG1,ITGA2,CNTN1,ANKRD13D,ROBO2,CKAP2,KIF5C,USP30,SFXN3,EPHB1,BEX2,LRRN1,PRICKLE2,CCDC122,SLC6A15,KLF9,MYO6,FES,MN1,RIN2,ARHGEF28,LRRIQ1,MCF2L2,CACNA1E,SNTB1,ZFPM2,GPR37,DPY19L2,ADAMTS17,TRIB3,PLPPR2,FBN1,SLCO5A1,DOCK6,CACNA2D1,ATP2B4,ABCG1,TLL2 |
| 1.450e-05 | -11.14 | GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_UP | 148 | 32 | 17377 | 1707 |
GXYLT2,KLF8,TTC39B,REL,HEBP1,HECW2,IL13RA1,LCP2,SATB1,ABHD6,RAC3,HECTD2,TLR3,SLC30A4,MARCKS,FKBP14,FMNL2,RASGRP1,GCA,QSOX1,KDM5B,CRIM1,TRAM1L1,AIG1,CDC42BPA,DCBLD2,CXCL10,PLOD2,GNB4,PCGF2,UACA,TANC2 |
| 1.469e-05 | -11.13 | tibia | COSMIC cancer mutations | tibia | 853 | 121 | 17385 | 1698 |
DMXL2,MYCBP2,THOC5,ACSL1,RASAL2,DOCK1,CNTNAP3,PLEKHA5,PLXNA2,COL18A1,ADD2,NDRG2,ZNF83,GRK6,TMEM170B,LCP2,DENND3,CA8,FSTL5,ANKRD42,EOMES,UNC13B,SLC22A17,CNKSR3,SLC22A18,RPS6KL1,REEP1,ITGB3,COL19A1,CPE,ETV1,NEB,INTU,GPM6A,MARK1,ABCC4,MVD,TCEAL3,TNS1,SAV1,SESN1,DSP,C4BPB,GSN,ZNF93,PTPRJ,GYPC,KPNA3,BACH2,ATP7B,WWTR1,PLEKHG1,NCOA7,TNFSF15,DSEL,DNHD1,PSPH,CTNND2,MAST1,CARS,TNIK,TMEM63C,SCN5A,ZHX3,ITPRIP,REL,CLSTN2,NKAIN2,TJP1,ZNF215,FAM174B,COL27A1,NEDD4,MTUS1,ABLIM1,TECPR1,SOAT2,IGF1R,FRAS1,PCBP4,PRKG1,SMTN,LRP6,ADCY6,RALGAPA2,TRIM3,FAR2,GPR161,CAND2,HMGCR,PARP9,EPB41L5,FGFR4,PTCH2,VAV3,SH3BP2,PNP,SLC36A1,MYO10,MSTN,CACNA1E,NR4A1,OBSCN,ST6GALNAC3,ATP11A,SDK1,PALLD,ZFPM2,PLCB1,NAALADL2,SMPDL3B,DAGLA,FGR,MAP2K6,FAT1,LRRIQ3,CDH17,LAPTM4B,CDH2,SIX2,SNPH |
| 1.472e-05 | -11.13 | positive regulation of cell differentiation | biological process | GO:0045597 | 928 | 128 | 17256 | 1658 |
ACVR1,TRIM16,GATA3,STAT5B,CEBPA,PRKCA,RAC3,RND2,EOMES,PACSIN1,SLIT2,IL1RAP,RASGRP1,GCNT2,FEZ1,ACVR2B,SAV1,GPRC5B,NCKAP1L,SEMA3C,SERPINI1,DLX2,NRP1,TNFSF4,MAGI2,MEF2C,EFNB2,RUNX2,FN1,LGALS3,PTPRD,ZHX3,FOXG1,NUMBL,CA2,GATA2,GRIP1,TOX,ZNF385A,RIMS2,EPB41L5,PAK1,PTCH2,DISC1,BDNF,PNP,VLDLR,SMARCD3,PRDM1,PLCB1,BAIAP2,NEGR1,RIPOR2,HEYL,CSF1,CDH2,SEMA3A,TESC,SHTN1,SFN,EPHA3,NBL1,BTC,PRKN,DOCK1,IL15,MSR1,PLXNA2,NTRK3,SEMA6A,PPP1R9A,CTNNA2,SCIN,CD53,BCL6,ACVR2A,DAB2IP,ZNF365,ZNF488,CTH,IGFBP3,FZD1,MYLK3,FZD4,SHANK2,PREX1,RARRES2,ATOH1,AMIGO1,DOCK5,FGFR1,SMAD3,PTK7,WWTR1,KLF5,HGF,BMPR1A,COBL,CNTN1,ROBO2,BMPR2,PLAG1,APBB1,OVOL2,GAS6,ZNF219,GDPD5,BMP6,NKX6-1,SCN1B,SH3PXD2B,FIG4,SYK,TESPA1,FES,VEGFC,TRPM4,PDLIM7,RAPGEF2,DKK1,MAP1B,CEBPB,MYADM,TERT,XBP1,BMP4,SHOX2,FOXA1 |
| 1.495e-05 | -11.11 | neuron to neuron synapse | cellular component | GO:0098984 | 233 | 43 | 18223 | 1724 |
DNM3,CACNG3,BMPR2,GRIK2,LRP4,CLSTN2,PSD3,ADD2,P2RY1,PPP1R9A,PCLO,CTNNA2,ARHGAP44,NCS1,EPB41L3,LIN7A,MPDZ,BNIP3,CHRM3,DLGAP1,DISC1,LZTS3,CAP2,SHANK2,HOMER2,DNAJC6,GRID1,NLGN4X,ARHGAP32,CPEB1,BAIAP2,HOMER3,MAP1B,CAMK2N1,GRIK4,MAP2,MPP2,PTPRS,GRIN2D,DLG2,CDH2,MAGI2,LZTS1 |
| 1.498e-05 | -11.11 | GO_CYTOPLASMIC_REGION | MSigDB lists | GO_CYTOPLASMIC_REGION | 276 | 50 | 17377 | 1707 |
GRIK2,STXBP6,EPS8,RGS20,ITPR2,GPSM2,CANX,SPINK5,PCLO,HMCN1,PPP1R9A,SPIRE1,NEDD4,SCIN,FRY,KCNAB1,MARCKS,CTTN,MYO6,MYRIP,DBN1,PHLDB2,FER,USP2,PXN,MYO10,WLS,EXOC6B,MPP1,DSTN,CRIP2,LRRK2,FERMT2,PLS1,ARHGAP32,ASPH,SNCA,GABARAPL1,GSN,PLEKHH2,MYADM,GYPC,WIPF3,RAI14,SEPT5,FNBP1L,CTTNBP2,CDH2,COBL,KIF1B |
| 1.498e-05 | -11.11 | HELLER_HDAC_TARGETS_DN | MSigDB lists | HELLER_HDAC_TARGETS_DN | 276 | 50 | 17377 | 1707 |
SEC24D,ST6GAL1,OLAH,SETBP1,CBS,CTBP2,CHAC1,BAG3,ZBTB38,SLC7A11,PMAIP1,MYC,PPFIBP1,EHD3,SLC6A15,PDE4D,SERPINH1,TSHR,CTH,ITGB7,SLC3A2,ATF4,DCC,LRMP,DEPTOR,NFE2L1,PHACTR2,ATF3,GSTO1,SNTB1,GALNT14,HERPUD1,HOMER3,ISG20,CEBPB,PTPRC,TRIB3,AK1,XBP1,SLC7A5,INHBE,FAM149A,HGF,MYOM2,MAPK13,TNFRSF17,TTC39A,LARP1,PSPH,DDIT3 |
| 1.500e-05 | -11.11 | regulation of cell morphogenesis | biological process | GO:0022604 | 471 | 74 | 17256 | 1658 |
PRKN,DNM3,ID1,ZSWIM5,FGF13,DOCK1,RHOD,PLXNA2,HECW2,NTRK3,RAC3,PPP1R9A,RND2,EPB41L3,PDZD8,RAP2A,CTTN,SLIT2,SSH3,FZD4,DCC,LRRK2,PREX1,AGO4,AMIGO1,DOCK5,WIPF3,MAP2,GBP1,ALDOA,PTPRS,SEMA3C,TPM1,SPART,NRP1,UST,WASF3,TNIK,ROBO2,BMPR2,FN1,BVES,PTPRD,RHOBTB1,LRP4,EPS8,ARHGAP44,NEDD4,NKX6-1,CHN1,KIAA1958,SEMA4F,GRIP1,FMNL2,RIMS2,FES,PAK1,BDNF,LZTS3,ENAM,RHOQ,MYO10,RAPGEF2,FERMT2,BAIAP2,MAP1B,FGR,MYADM,ADGRB3,RND3,SHOX2,SEMA3A,CDH2,SHTN1 |
| 1.501e-05 | -11.11 | protein homodimerization activity | molecular function | GO:0042803 | 829 | 118 | 17224 | 1680 |
NBL1,ID1,ACVR1,GRIK2,LILRB1,JCHAIN,ADD2,NPM1,CEBPA,MAPK4,CTBP2,CHUK,CADM2,ABAT,SNX9,RBM11,IKZF2,CBLN1,PPP1R9A,SLC9A7,QPRT,RIDA,TYMP,ASNS,KCNN2,AADAT,GRHL1,CFHR1,GSTM3,DAB2IP,ENO1,SLIT2,RASGRP1,GLDC,GCA,NR6A1,FZD4,MVD,LRRK2,BNIP3L,CR2,NLGN4X,CBY1,ATF3,JAM3,FGFR1,WARS,SMAD3,TRIM9,ENPP1,IKZF3,GYPC,RBPMS2,GBP1,ERN1,WWTR1,MAP3K21,HPGD,SOHLH2,ERCC5,INPP5F,BMPR1A,TPM1,MID1,PSPH,CHMP4C,CRYL1,TENM1,CARS,ZHX3,GRB14,SLK,FBXO4,LRP4,CBS,ADSSL1,TPD52L1,GRPEL2,IL17D,FOXP2,FSD1,ZBTB38,HMGCS1,PRTFDC1,PDZD7,FLRT3,BHLHA15,STC2,GHR,TFAP2A,LRP6,PRKG2,BNIP3,HMGCR,MID2,ATP5IF1,CDH26,GSTM2,MSTN,GSTM4,HOMER2,FASN,HIP1,MAFB,LHPP,RACK1,PLCB1,CEBPB,SH3GL2,TERT,NACC2,CSF1,HEYL,CDH2,TESC,DDIT3,ABCG1,STOM |
| 1.511e-05 | -11.10 | Golgi apparatus | cellular component | GO:0005794 | 1505 | 190 | 18223 | 1724 |
CCDC126,ATP8A1,LDLR,NDRG2,CHAC1,MGAT5B,BCAN,SNX9,CHST10,SLC9A7,STK24,NCS1,SEC16B,GRHL1,RAB26,KCNS3,JAKMIP2,TMED9,CTTN,COG3,CPE,GALNT18,RASGRP1,PDGFRB,ATL1,CD55,KCNIP3,GCNT2,ERGIC1,WLS,TGFA,LRRK2,FEZ1,ZDHHC14,GPC6,SH3RF1,ATP7B,TNFRSF1A,B3GALT2,BMP1,DSEL,PCSK5,PRKAA2,UST,INPPL1,HID1,SEC24D,ST6GAL1,DHCR24,GALNT13,CHSY1,APBA1,MTUS1,GBGT1,GALNT1,ABCA5,BACE2,SREBF1,PRKG1,HS3ST5,LRP6,LMAN2,ST8SIA1,NCAM1,NOS3,CHSY3,FGFR4,QSOX1,IL17RD,PODXL2,PLEKHA8,MGAT4B,GPSM1,FASN,SDC3,HIP1,ST6GALNAC3,GALNT17,SNAP25,RABAC1,B4GALNT3,CLN5,BAIAP2,GLCE,SH3GL2,PLAGL1,PMEPA1,PKN3,QPCTL,RAB31,SELENOM,PLD1,RNF122,PLA2G4A,PRKN,DNM3,ID1,PCSK1N,SCAMP1,RNF144A,IL15,LPCAT2,GALNT12,GALNT6,XYLT1,MYO1B,RGS20,RNF24,FAM198B,COLEC10,TLR3,UNC13B,ZDHHC6,BCL6,ZDHHC23,NBEA,PROS1,RAB27B,JAKMIP3,CLVS2,PERP,B3GALT1,TDRD3,TMEM43,ACO1,RNF125,CBY1,PXYLP1,RAB38,JAM3,GABARAPL1,SNCA,ARHGAP21,GBP1,ASIC1,PAM,KLF5,HS3ST3B1,RAB30,HACE1,RETREG1,TENM1,SERINC5,IGFBP6,BACE1,ATP9A,FZD8,ARL2,CLSTN2,GAS6,NDFIP2,SLC35G2,NEDD4,NEO1,GSAP,RAB11FIP5,FUT9,MGAT1,STC2,TFAP2A,RMDN2,TRIM3,FIG4,DYNC2H1,MYO6,SMAD6,FES,PCSK6,B4GALT6,TRPM4,RAB6B,CYTH3,SYBU,LITAF,ZDHHC15,ARHGAP32,FNDC3A,TLR6,GALNT14,GALNT3,ICA1,RND3,ACER2,MYRF,RPS12,CERS1,MMP16,B4GALT7,ABCG1,ATP1A3 |
| 1.521e-05 | -11.09 | GO_INTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE | MSigDB lists | GO_INTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE | 1567 | 203 | 17377 | 1707 |
ACVR1,CACNG3,LGR4,GRIK2,LDLR,CADM2,SLC2A13,ABHD6,SLCO3A1,NOS1AP,PCDH7,F3,EPCAM,TGFBR3,TM9SF2,KCNAB1,HPS1,SLC16A2,ITGB3,RAB26,KCNS3,TRPC1,SLC2A12,CTTN,EPHB6,TLR4,TSHR,IL1RAP,PDGFRB,ITGB7,CD55,KCNIP3,ACVR1C,TGFA,LRMP,ABCC2,ACVR2B,KCND3,ROR1,GPC6,SLC7A1,ENPP1,TMEM150B,KCNMB4,NCKAP1L,ATP7B,TNFRSF1A,ADRB1,OXTR,TNFSF4,TYRO3,EFNB2,KCNV1,SEMA6B,SCN5A,CELSR1,PTPRD,GABRB2,SCN8A,ITGA6,TNFRSF10C,GAS1,IGF1R,SEMA4F,SLC7A11,CACNB2,FLRT3,OPN3,ADCY6,TSPAN12,LMAN2,SLCO4C1,JAM2,TSPAN9,LRP12,CHRM3,FGFR4,GPR176,IL17RD,PODXL2,KCNQ3,EFNA3,CALCRL,SNAP25,GPR19,STEAP1,MMP15,KCNK15,GRIK4,MFSD2A,FAT1,SLC2A6,MPP2,PTPRN2,TRPC3,MME,CXCR5,EPHA3,SORBS1,RASAL2,IL15,ST14,GPR65,PLXNA2,MSR1,NTRK3,IL13RA1,CHUK,SLC7A2,NRXN1,DDR1,SLC19A2,SEMA6A,CD53,GPR15,TLR3,SLC22A17,CHRNA5,COL25A1,ACVR2A,DAB2IP,STEAP3,SCN2A,MET,NTNG1,PERP,SEMA6C,KCNB2,SCN3A,PTPRU,FZD4,KCNH5,SLC39A8,SHANK2,ADCY1,NLGN4X,CHRNA6,AMIGO1,ATP1B1,CD40,FGFR1,DCBLD2,HTR7,SLC39A14,ENTPD1,NRG3,PTPRJ,GYPC,PTK7,TMPRSS9,KCNG1,ITGA2,PTPRS,TNFSF15,HS3ST3B1,LIFR,LPAR2,SLC6A9,EDA2R,BMPR2,TSPAN15,BACE1,EPS8,GABRG2,SELL,GABRR2,SLC12A6,P2RY1,EPHB1,KCNC4,TSPAN17,NEO1,KCNJ4,SCN1B,GHR,KCNMB3,TSPAN13,SLC6A15,TNFRSF11A,ATP2B1,ULBP1,SLC40A1,RAPGEF2,MPP1,PRRG1,RASA3,TLR6,GPR37,PTPRC,CD37,SLC7A5,SLCO5A1,GRIN2D,DLG2,SLC1A5,IL9R,MMP16,SLC16A10,ATP2B4,ATP1A3,ABCG1,SLC43A1,STOM |
| 1.525e-05 | -11.09 | SENESE_HDAC1_TARGETS_DN | MSigDB lists | SENESE_HDAC1_TARGETS_DN | 225 | 43 | 17377 | 1707 |
GXYLT2,MRC2,TRIM2,RUNX2,ZNF395,AASS,YPEL2,ASS1,ENAH,PRKCA,TIAM2,ZNF827,LRRN1,JAKMIP2,NAP1L3,LOXL4,CPE,TMEM120B,TMEM56,PNMA2,HMGCR,FADS1,EPB41L5,SSH3,PHLDB2,ERGIC1,GSTM2,TUBA1A,GSTM4,ARID5B,BNIP3L,NFIA,SDC3,TNS1,GPR137C,FGFR1,BAIAP2,EBF1,GSN,MPP7,BMP4,CSRP2,CRISPLD1 |
| 1.542e-05 | -11.08 | GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 1460 | 191 | 17377 | 1707 |
ARHGAP26,ACSL1,FGF13,DOCK3,PRKCA,FAM13A,SNX9,NOS1AP,F3,ARHGEF10L,ADPRHL1,SIPA1L2,PMAIP1,ITGB3,SERINC2,PCOLCE2,TLR4,TSHR,RAPGEF5,RASGRP1,PRKACB,PDGFRB,TBC1D8,COL4A3,ACVR1C,TGFA,CAP2,LRRK2,ELMOD1,PRKAR2B,ACVR2B,FGF17,SERGEF,ARHGEF26,GSN,GPRC5B,NCKAP1L,RASGRF2,ERN1,ADRB1,ARHGAP28,BBC3,DIRAS1,TPM1,MAGI2,MEF2C,RGS16,FN1,ALOX5AP,STXBP5L,TBC1D1,ITGA6,OPHN1,PFN2,CHN1,RALGPS2,MYC,PRELID1,SRGAP1,ADCY6,NCAM1,DENND1C,GFRA1,NOS3,FGFR4,PAK1,TBC1D8B,VLDLR,RAPGEF4,SPATA13,DUSP9,RYR2,HIP1,STRADB,OBSCN,ARRDC4,PLCB1,FAM162A,TBC1D2,MAPKAPK2,MMP15,CSF1,IQSEC2,FNBP1L,DOCK9,BTC,NEK10,AVPI1,RASAL2,AKAP5,DOCK1,GPR65,ARHGAP22,RGS20,NTRK3,LCP2,DENND3,PIBF1,DOCK2,TBC1D30,PPP1R9A,TIAM2,TBC1D19,TLR3,CDC14B,DAB2IP,MARCKS,HSPA2,PERP,DOCK8,IGFBP3,PFKFB2,FZD4,ADCY1,PREX1,PRKCQ,WNT11,ATP1B1,CD40,DOCK5,TBC1D16,ASPH,FGFR1,SNCA,SMAD3,IRS2,ARHGAP21,NRG3,WFS1,ITGA2,RGS10,DUSP19,PLEKHG1,HGF,TNFSF15,MAPK10,DENND5B,TNIK,SERINC5,LPAR2,FARP1,ARHGEF11,FZD8,PSD3,GAS6,RGS7,PKN1,TPD52L1,ARHGAP44,SYDE2,RGS17,CHN2,MCF2L,GHR,PRKCD,RALGAPA2,AFAP1L2,IQGAP3,TBC1D9,ERRFI1,TNFRSF11A,SPRY2,SYK,RIN2,VAV3,ARAP2,RAPGEF2,MCF2L2,CYTH3,ASAP3,RASA3,AGAP2,ARHGAP32,TLR6,GPLD1,PTPRC,SUGT1,TRIB3,FGR,DOCK7,TERT,MAP2K6,ACER2,GNAO1,GRIN2D,BMP4,TBC1D4,MMP16,DOCK6,ATP2B4,BTRC |
| 1.543e-05 | -11.08 | regulation of system process | biological process | GO:0044057 | 570 | 86 | 17256 | 1658 |
MTG1,CACNG3,FGF13,LMCD1,PKP2,ITPR2,ABAT,NRXN1,PRKCA,CACNB4,CBLN1,NOS1AP,TYMP,FBXO32,UNC13B,KCNN2,TRPC1,PDE4D,CTTN,ENO1,KCNB2,KCNIP3,TMEM65,ANK2,SHANK2,LRRK2,FGF12,NLGN4X,GSTO1,KCND3,ATP1B1,DSP,ASPH,DOCK5,FGFR1,GJC1,SMAD3,KCNMB4,APELA,ITGA2,ADRB1,HGF,OXTR,TPM1,PPARGC1A,WASF3,SCN5A,C1QTNF3,BMPR2,BVES,CYP2J2,GTF2IRD1,GAS6,BMP6,RAB11FIP5,KCNJ4,IRX5,SCN1B,CACNB2,EHD3,DSG2,SREBF1,PRKG1,SGK1,FIG4,ERRFI1,ATP2B1,RIMS2,CHRM3,NOS3,PAK1,TRPM4,GSTM2,MSTN,CALCRL,RYR2,BAIAP2,KCNK15,GNAO1,GRIN2D,MYRF,SEMA3A,TRPC3,CACNA2D1,ATP2B4,ATP1A3 |
| 1.553e-05 | -11.07 | anatomical structure formation involved in morphogenesis | biological process | GO:0048646 | 842 | 118 | 17256 | 1658 |
UGT8,AMOTL1,ACVR1,ID1,ST14,ARHGAP22,PLXNA2,GATA3,COL18A1,PRKCA,CBLN1,SKI,EPB41L3,TYMP,TGFBR3,EOMES,DLX6,ITGB3,BCL6,DAB2IP,SLIT2,PERP,PRKACB,PDGFRB,SNAI2,NKX2-1,CYP1B1,FZD1,MYLK3,CEMIP2,ADM2,NKX3-2,WLS,ANK2,PTPN6,WNT11,ACVR2B,JAM3,FGFR1,WARS,SMAD3,DYRK1B,NRG3,HPSE,CCBE1,PTK7,APELA,LAMB1,ITGA2,AHNAK2,KLF5,SEMA3C,TMOD2,BMPR1A,UNC5B,NRP1,TPM1,VASH2,COBL,MEF2C,HEY1,EFNB2,CELSR1,BMPR2,FN1,ITGA6,FZD8,OPHN1,OVOL2,SLC12A6,EPHB1,ZNF219,ADGRG6,FHOD3,HOPX,GATA2,TFAP2A,LRP6,TSPAN12,LOXL4,FIG4,SYK,ZNF385A,DUSP1,NOS3,FGFR4,VEGFC,EPB41L5,ENAM,ATP5IF1,VAV3,SLC40A1,MSX1,SH2D2A,NR4A1,DCHS1,FHL2,SMARCD3,CALCRL,PRICKLE1,OBSCN,MAFB,SDK1,HOXA1,LEPR,GPLD1,DKK1,MMP15,ADGRB3,EDA,PRCP,HEYL,XBP1,EGFL7,MYOM2,BMP4,FOXA1,SIX2 |
| 1.570e-05 | -11.06 | postsynaptic specialization | cellular component | GO:0099572 | 226 | 42 | 18223 | 1724 |
DNM3,CACNG3,BMPR2,GRIK2,LRP4,CLSTN2,PSD3,ADD2,P2RY1,PCLO,PPP1R9A,CTNNA2,ARHGAP44,NCS1,EPB41L3,LIN7A,MPDZ,BNIP3,DLGAP1,DISC1,LZTS3,CAP2,SHANK2,HOMER2,DNAJC6,GRID1,NLGN4X,ARHGAP32,CPEB1,BAIAP2,MAP1B,HOMER3,CAMK2N1,GRIK4,MAP2,MPP2,PTPRS,DLG2,GRIN2D,MAGI2,CDH2,LZTS1 |
| 1.598e-05 | -11.04 | regulation of cellular component movement | biological process | GO:0051270 | 991 | 135 | 17256 | 1658 |
ACVR1,FGF13,RECK,ATP8A1,GATA3,PRKCA,ABHD6,STK24,NOS1AP,F3,RND2,TGFBR3,TCAF2,RAP2A,ITGB3,SLIT2,PDGFRB,NKX2-1,CYP1B1,GCNT2,ACVR1C,ANK2,FEZ1,NCKAP1L,CCBE1,PLK2,SEMA3C,INPP5F,TPM1,NRP1,PPARGC1A,TMEFF2,MAGI2,SPOCK3,FRMD5,MEF2C,SCN5A,FN1,LGALS3,RHOBTB1,ITGA6,SLK,PFN2,MTUS1,IGF1R,SEMA4F,GATA2,SRGAP1,PRKG1,NOS3,EPB41L5,PAK1,UNC5C,SPATA13,RYR2,PLCB1,BEX4,RIPOR2,THBS4,CSF1,SEMA3A,SHTN1,NBL1,BTC,ZSWIM5,AMOTL1,RHOD,DOCK1,PLXNA2,PKP2,COL18A1,NTRK3,SEMA6A,BCL6,DAB2IP,PDE4D,MET,SNAI2,DOCK8,IGFBP3,FER,PHLDB2,EVL,PTPRU,PREX1,WNT11,RARRES2,SYNJ2BP,CD40,DOCK5,DSP,JAM3,FGFR1,SMAD3,ARMC4,IRS2,CXCL10,NRG3,PTPRJ,APELA,LAMB1,ABI3,ITGA2,HGF,BMPR1A,HACE1,BMPR2,GAS6,PKN1,PHLDA2,NKX6-1,DSG2,SGK3,SGK1,RRAS2,SPRY2,FES,VEGFC,TRPM4,RAPGEF2,MPP1,RACK1,GPLD1,PTPRC,FGR,DOCK7,MYADM,GCSAM,TERT,RND3,AKT3,PRCP,XBP1,MCC,BMP4 |
| 1.602e-05 | -11.04 | DAWSON_METHYLATED_IN_LYMPHOMA_TCL1 | MSigDB lists | DAWSON_METHYLATED_IN_LYMPHOMA_TCL1 | 56 | 17 | 17377 | 1707 |
PCDH10,PTPRD,FOXG1,GAS1,ARHGEF26,RNF180,ISM1,CADPS2,KIAA0408,HOXD13,FIGN,NCAM1,CLVS2,PRR16,KLHL29,OSBPL6,SPRY2 |
| 1.607e-05 | -11.04 | GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION | 1143 | 155 | 17377 | 1707 |
ACVR1,DUSP8,LGR4,GRIK2,GATA3,NDRG2,CHAC1,ABHD6,SKI,TGFBR3,ZFYVE28,CHRDL1,CTTN,TLR4,PTPRE,SLIT2,PRKACB,NKX2-1,ACVR1C,LRRK2,DEPTOR,YAP1,FEZ1,PLEKHA1,TSKU,GNAI1,ENPP1,SH3RF1,PLK2,INPP5F,DLX2,SPRY4,UNC5B,NRP1,MAGI2,MLLT3,LZTS1,TYRO3,PRKAA2,LATS2,RGS16,RUNX2,LGALS3,STXBP5L,ITGA6,UBASH3B,RASL11B,DDIT4,MECOM,IGF1R,PIK3AP1,BCHE,GATA2,FLRT3,MYC,C1QL4,PRELID1,SREBF1,LRP6,STXBP1,BARX1,ZNF385A,GPR161,NOS3,RNF152,HMGCR,PTCH2,QSOX1,MSTN,DUSP9,WWC1,STRADB,PRDM1,HERPUD1,SH3GL2,PMEPA1,HEYL,SH3BP4,EGFL7,CDH2,NBL1,RASAL2,RGS20,GRK6,PIBF1,PPP1R9A,CYP26A1,TLR3,DACT1,CNKSR3,BCL6,DAB2IP,WWC2,SNAI2,CTH,FZD1,GLI1,IGFBP3,PRAME,PTPN6,SHANK2,NLGN4X,CBY1,ATF3,WNT11,GSTO1,PRKCQ,SYNJ2BP,SNCA,SMAD3,PTPRJ,PRKCB,GBP1,WFS1,WWTR1,DUSP19,RGS10,HGF,GRB10,HEY1,IGFBP6,C1QTNF3,LRP4,NOTUM,GAS6,OVOL2,RGS7,GDPD5,PPP2R3A,NEDD4,RAB11FIP5,RGS17,PRKCD,ERRFI1,SMAD6,SPRY2,DUSP1,GSTM2,LITAF,RASA3,PRICKLE1,SMPDL3B,DKK1,PTPRC,MYADM,FBN1,TERT,XBP1,PCGF2,MCC,BMP4,BTRC,ATP2B4,DDIT3,TPT1 |
| 1.608e-05 | -11.04 | GSE6259_BCELL_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_BCELL_VS_CD8_TCELL_UP | 176 | 36 | 17377 | 1707 |
WASF3,ZNF395,RNF144A,XYLT1,NKAIN2,KIF5C,CEBPA,CREB5,LACC1,CA8,INPP1,ZSCAN5A,DDIT4,EPB41L3,BAG3,SIPA1L2,SETDB2,SLC7A11,CHRDL1,EEPD1,ADCY6,TBC1D8,CYP1B1,MN1,MICAL2,JPH1,TNS1,RAB38,AHRR,NACC2,PEMT,RGS10,ZNF704,BMPR1A,PKIA,STOM |
| 1.608e-05 | -11.04 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN | 176 | 36 | 17377 | 1707 |
AVPI1,FN1,RASAL2,GPR65,UBASH3B,TNFSF13B,IL13RA1,CREB5,SLC1A3,TRPS1,CA2,KLF9,NCEH1,ERRFI1,STXBP1,IL1RAP,CYP1B1,PFKFB4,ITGB7,GAPDH,SKAP2,SPOCD1,LRRK2,PRDM1,DHX32,HOMER3,GJC1,C11orf45,GABARAPL1,PRCP,PLXDC2,SRD5A3,KIAA0513,SQLE,DISP1,DIRC2 |
| 1.608e-05 | -11.04 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP | 176 | 36 | 17377 | 1707 |
SERINC5,GNG12,TRIM2,ACSL1,BLVRB,KCTD12,COL4A5,MECOM,CDS1,PLS3,FRY,CPVL,MSMO1,KAZN,TBC1D9,CEBPD,SMPDL3A,CRIM1,DSTN,VLDLR,DUSP9,PLS1,PDE8A,ATP1B1,ATP10D,HERPUD1,GNAI1,IQCK,GPRC5B,PRCP,XBP1,MATN2,DYNC2LI1,SEMA3C,MAGI2,ACSM3 |
| 1.617e-05 | -11.03 | HALLMARK_MTORC1_SIGNALING | MSigDB lists | HALLMARK_MTORC1_SIGNALING | 197 | 39 | 17377 | 1707 |
DHCR24,LDLR,SCD,CANX,PHGDH,DDIT4,CYP51A1,HMGCS1,IDI1,ASNS,SLC7A11,STARD4,SERPINH1,ENO1,CTH,HMGCR,FADS1,GAPDH,SKAP2,PNP,PDK1,TES,VLDLR,AK4,CCNG1,WARS,TRIB3,INSIG1,PLOD2,ALDOA,XBP1,SLC7A5,HK2,SQLE,P4HA1,SLC1A5,DHCR7,PSPH,DDIT3 |
| 1.623e-05 | -11.03 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN | 190 | 38 | 17377 | 1707 |
EXPH5,RUNX2,TTC39B,BMPR2,FBXO4,KIF5C,ABHD4,SNX9,TSPAN17,EPDR1,SCIN,TXNDC5,HOPX,GPR15,PPFIBP1,PRELID2,TSC22D1,MED7,NEB,MID2,RIN2,SKAP2,TMEM65,GJB2,WLS,FHL2,LITAF,PRDM1,CRYBG3,ATP10D,GABARAPL1,IKZF3,HPSE,CLDN12,SLC22A15,NRP1,IL9R,ATP2B4 |
| 1.623e-05 | -11.03 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN | 190 | 38 | 17377 | 1707 |
ANO10,LATS2,RUNX2,ALOX5AP,ST14,ZCCHC24,BLVRB,SELL,IL13RA1,TMEM170B,CANX,PRRG4,ARHGEF10L,TRIM3,LIN7A,DYNC2H1,FAR2,SUSD3,GCA,MICAL2,VNN2,ALDH2,KLHL23,BNIP3L,SMARCD3,EFHC1,SNTB1,BATF,PLCB1,HOMER3,ATPAF2,MPP7,PLXDC2,PTPRN2,CLMN,SEMA3C,PLD1,SLC43A1 |
| 1.623e-05 | -11.03 | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | MSigDB lists | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | 190 | 38 | 17377 | 1707 |
SERINC5,ID1,ENO2,RASL11B,C20orf194,ADAMTS6,STAT5B,ZNF219,SATB1,NUDT12,CA8,DDR1,HECTD2,TBC1D19,SKI,CCNJ,SLC22A17,ADCY6,ST8SIA1,DYNC2H1,PACSIN1,TMEM120B,RNF145,KLHL4,LRMP,GPSM1,ZDHHC15,RASA3,ATP11A,CTIF,CAMK2N1,IRS2,GPRC5B,PMEPA1,RNF157,TBC1D4,SLC43A1,PHC1 |
| 1.630e-05 | -11.02 | CHEBOTAEV_GR_TARGETS_UP | MSigDB lists | CHEBOTAEV_GR_TARGETS_UP | 73 | 20 | 17377 | 1707 |
C2orf88,DNM3,RECK,ST6GAL1,NDRG2,DOCK5,TTLL7,TTC28,SEMA6A,NT5DC2,RAB11FIP5,ENPP1,P4HA2,STC2,HPGD,COL19A1,TSPAN13,GULP1,NRP1,FZD1 |
| 1.654e-05 | -11.01 | XU_GH1_AUTOCRINE_TARGETS_DN | MSigDB lists | XU_GH1_AUTOCRINE_TARGETS_DN | 129 | 29 | 17377 | 1707 |
EFNB2,DBN1,GDAP1,UNC5C,RHOQ,KDM5B,REL,SLK,UGDH,ARID5B,PREX1,ADCY1,TJP1,GPR180,CDC42BPA,NAALADL2,DYRK1B,CA2,HPSE,PMEPA1,MCF2L,PLK2,NDUFB8,RAB31,NBEA,GSTM3,SEMA3C,TPM1,CTNND2 |
| 1.658e-05 | -11.01 | astrocytoma_Grade_I | COSMIC cancer mutations | astrocytoma_Grade_I | 143 | 31 | 17385 | 1698 |
GARS,NECAB1,KLHL13,THSD4,NKAIN2,AIG1,LRRC49,ZFPM2,NAALADL2,DOCK2,HMCN1,ATP10D,FSTL5,FGFR1,ARHGAP44,NEGR1,TPK1,CDS1,GNAI1,NRG3,TERT,NACC2,PLXDC2,PDE10A,PRKG1,RNF130,NRP1,TBC1D9,MET,MAGI2,KIAA1549 |
| 1.665e-05 | -11.00 | CAATGCA,MIR-33 | MSigDB lists | CAATGCA,MIR-33 | 91 | 23 | 17377 | 1707 |
DPYSL5,MEIS2,SCN8A,SHANK2,ARID5B,SATB2,ATP1B1,MECOM,BCL11A,IRS2,CDR2L,CHN2,ICA1,CNTN4,KPNA3,RAP2A,TMEM86A,KCNS3,B3GALT2,PRICKLE2,PPARGC1A,MMP16,MLLT3 |
| 1.675e-05 | -11.00 | GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 149 | 32 | 17377 | 1707 |
DPP10,TNIK,KCNIP3,FGF13,TSPAN15,ANK2,RAPGEF2,PKP2,GAS6,ATP1B1,P2RY1,SKAP1,TSPAN17,EPB41L3,MYADM,FCHO2,CACNB2,EHD3,RAP2A,TNFRSF1A,RAB26,ZDHHC23,RAB31,MAP7,LRP6,LIN7A,PRKG2,PACSIN1,STXBP1,CDH2,TESC,KCNB2 |
| 1.696e-05 | -10.98 | import across plasma membrane | biological process | GO:0098739 | 63 | 18 | 17256 | 1658 |
TRPM4,SLC3A2,SLC9C1,SLC39A8,SLC36A4,ATP1B1,SLC1A3,SLC7A2,STEAP1,SLC9A7,SLC39A14,SLC7A1,STEAP3,SLC1A5,FAM155B,FAM155A,CACNA2D1,ATP2B4 |
| 1.764e-05 | -10.95 | GOZGIT_ESR1_TARGETS_UP | MSigDB lists | GOZGIT_ESR1_TARGETS_UP | 136 | 30 | 17377 | 1707 |
UGT8,RNF144A,PTPN21,FHL2,DUSP9,FERMT2,WWC1,KCTD12,PRKAR2B,CEBPA,FAM13A,GDPD5,ASPH,GAS1,CYP26A1,GNAI1,FSD1,FRY,GRHL1,GATA2,VWDE,LAMB1,TFAP2A,DUSP19,LIMCH1,PLD1,SMPDL3A,ABCG1,GLDC,IGFBP3 |
| 1.764e-05 | -10.95 | GACAATC,MIR-219 | MSigDB lists | GACAATC,MIR-219 | 136 | 30 | 17377 | 1707 |
SCN5A,ERGIC1,PTPRU,FZD4,RECK,UBASH3B,ZCCHC24,MCF2L2,SLK,ELOVL7,DNAJC6,HOMER2,ABHD13,ADD2,PHACTR2,SDK1,DCBLD2,ZNF827,DDAH1,INSIG1,SLC30A4,AFAP1L2,KLF9,PDE4D,PPARGC1A,PURG,KIF1B,NTNG1,FMNL2,LPP |
| 1.769e-05 | -10.94 | RICIN_B_LECTIN | prosite domains | PS50231 | 29 | 12 | 12060 | 1278 |
GALNT3,GALNT1,MRC2,DCDC1,GALNT6,GALNT12,CRYBG1,GALNT17,GALNT13,GALNT14,GALNT18,CRYBG3 |
| 1.773e-05 | -10.94 | CAGGTA_V$AREB6_01 | MSigDB lists | CAGGTA_V$AREB6_01 | 725 | 106 | 17377 | 1707 |
PHACTR3,NEK10,AVPI1,TTC39B,FGF13,RBFOX2,HEBP1,VAMP8,IL13RA1,CADM2,DACH2,CBLN1,SP8,SLC9A7,TRPS1,ZNF827,RUFY4,NELL2,ZNF362,KCNAB1,RPS6KL1,LHX6,REEP1,BCL6,KCNS3,NBEA,FHIT,PPP2R2B,PDE4D,PRKACB,GPM6A,SLC3A2,KCNH5,PRDM13,NFIA,TCEAL3,MSRB3,SLC25A28,CBY1,KCND3,CD40,BCL11A,ENPP6,PTK7,KLF5,HGF,NR3C2,PURG,BCL11B,TYRO3,LRFN5,ZNF395,FN1,CREB5,OVOL2,CHSY1,FAM81A,SEL1L3,FOXG1,TNFRSF19,BMP6,ARHGAP44,FOXP2,ATXN7L1,EFEMP1,CHN2,LRRN1,FRY,GATA2,CACNB2,SGK3,SRGAP1,TFAP2A,LOXL4,NCAM1,ERRFI1,SPRY2,BDNF,PCDH10,MSX1,ARAP2,USP2,PXN,MSTN,FOXN3,ESRRG,TMTC4,RYR2,WWC1,ST6GALNAC3,PLCB1,KHDRBS2,NAALADL2,ZIC1,CD37,PLAGL1,DLG2,BMP4,DISP2,NKX2-8,FNBP1L,OSBPL6,FOXA1,ATP1A3,DOCK9,PHC1 |
| 1.780e-05 | -10.94 | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP | 163 | 34 | 17377 | 1707 |
DYRK3,HECW2,TUBE1,P2RY1,CHAC1,SNX9,UBTD2,PHLDA2,ZSCAN5A,DDIT4,F3,ASNS,PMAIP1,STARD4,SPRY2,ATP2B1,DUSP1,SESN2,GARS,SLC3A2,SYNPO2,LRRC8B,RAPGEF2,FERMT2,SAV1,ASPH,INSIG1,CSF1,MFSD2A,CCNA1,SLC7A5,TNFSF15,PLD1,GEM |
| 1.785e-05 | -10.93 | ZHU_CMV_8_HR_DN | MSigDB lists | ZHU_CMV_8_HR_DN | 51 | 16 | 17377 | 1707 |
MN1,LDLR,ACO1,AARS,GAS1,DDIT4,TGFBR3,IGF1R,ZNF521,TFAP2A,TNFRSF1A,ACVR2A,ERCC5,BMP4,MARCKS,CEBPD |
| 1.785e-05 | -10.93 | BERNARD_PPAPDC1B_TARGETS_DN | MSigDB lists | BERNARD_PPAPDC1B_TARGETS_DN | 51 | 16 | 17377 | 1707 |
MXI1,SH3BP2,SCAMP1,CRIM1,GSTM4,KIF5C,HIP1,SEL1L3,PRR7,TBC1D2,NAV1,STC2,SH3BGRL2,FAR2,SUSD4,GLDC |
| 1.794e-05 | -10.93 | Ricin_B_lectin | interpro domains | IPR000772 | 31 | 12 | 18492 | 1811 |
GALNT3,GALNT1,MRC2,DCDC1,GALNT6,GALNT12,CRYBG1,GALNT17,GALNT13,GALNT14,GALNT18,CRYBG3 |
| 1.816e-05 | -10.92 | adrenal_gland | COSMIC cancer mutations | adrenal_gland | 2689 | 323 | 17385 | 1698 |
DOC2A,MYCBP2,PPP4R4,TCP11L2,GRIK2,ATP8A1,NPM1,CA8,PCDH7,IKZF5,DNAH6,POU3F3,MEIS2,DCC,KLHL3,KLHL4,LRMP,FEZ1,F12,MFSD6,ZDHHC14,INTS6,PYCR1,AHRR,ENPP6,MAP9,SEMA3C,ERCC5,ZBTB20,TANC2,DNHD1,SPOCK3,LRFN5,PTPRD,ZHX3,SCN8A,ITGA6,ST6GAL1,MRPL22,WDFY4,ADSSL1,GRPEL2,MTUS1,MCOLN2,SYCP2,FRY,KIAA1671,NOVA2,ZIC5,SRGAP1,GRIP1,CADPS2,ALPK1,FIGN,NCAM1,MOXD1,FAM155A,GPR161,CHRM3,QSOX1,MYO10,COL4A4,FASN,RYR2,ZNF558,CACHD1,TEX15,RIMKLB,PMEPA1,THBS4,MATN2,DHCR7,ACSM3,DOCK9,DNM3,RHOD,ST14,CCDC110,MYO1B,MSR1,PLXNA2,BEGAIN,PKP2,TBC1D30,TIAM2,NELL2,TMEM53,RNF150,ALDOC,ALDH1L1,SCRN1,NBEA,DAB2IP,ARL4D,RAB27B,DNAH5,GATM,KCNB2,SCN3A,DOCK8,C3orf67,FZD4,TRAM1L1,WNT11,PRKCQ,DSP,ATP10D,FGFR1,DCBLD2,ENTPD1,IRS2,GYPC,TDO2,LAMB1,INPP4B,PAM,TNFSF15,GRB10,HOXB9,CCDC148,FARP1,WDR17,EDA2R,ATP9A,FZD8,ESRP1,KIF5C,P2RY1,ZNF219,RGS7,GDPD5,IRX5,SOAT2,AFF2,GPR155,MED12L,PDLIM7,TRPM4,BCL7A,ARHGEF28,SYNPO2,SH3BP2,PTPN13,CTTNBP2NL,SKAP1,NSD1,PCDHB7,TERT,CLDN12,SLCO5A1,PGM2L1,NEK11,SVIL,MYOM2,HK1,OCLN,TLL2,EXPH5,KIF5A,PTPN21,FAM13A,HMCN1,CEP85L,SIPA1L2,SEC16B,KCNN2,GRHL1,ABI3BP,MARVELD2,POF1B,COL19A1,JAKMIP2,SLC2A12,TLN2,MYRIP,NEB,ZNF391,PGBD5,SLC3A2,COL4A3,ABCC4,SPOCD1,ANK2,GDPD1,RNF44,SERGEF,NT5DC2,TCF7L1,HPSE,OXTR,MAGI2,RRAGD,UST,BCL11B,MOCOS,LGALS3,STXBP5L,SEC24D,CYP4V2,SETBP1,GALNT13,CHSY1,SPINK5,DOK5,PCDHB14,EFEMP1,KIAA1958,GALNT1,KIAA0895,ZNF354A,SEMA4F,BCHE,FRAS1,EBF4,NCEH1,ZNF629,PAK1,GPR176,UNC5C,PCDH10,IL17RD,SH2D2A,PPFIA4,OBSCN,SDK1,LHPP,PRDM1,LDHD,TBC1D2,NAP1L5,GRIK4,KIAA0355,FAT1,HK2,NXPH4,XKR4,OSBPL6,SIX2,EML5,CFH,DOCK1,LPCAT2,PLEKHA5,NTRK3,BCL6B,PIBF1,TNKS1BP1,PPP1R9A,PCLO,SEMA6A,DOCK2,CYP26A1,ZSCAN5A,COL22A1,UNC13B,SETDB2,PPFIBP1,LHX6,FABP6,MYO3B,MYH15,STEAP3,MET,CLVS2,HSPA2,IGFBP3,PTPN6,ACO1,CHRNA6,VIM,DOCK5,JAM3,WARS,IFT81,NRG3,PTPRJ,PTPRS,MAOA,CTNND2,CNTN1,TENM1,PCDH18,ENO2,ARHGEF11,CLGN,CLSTN2,PRDM8,USP30,KCNJ4,TECPR1,MAP1A,RASD2,EHD3,STC2,TSC22D1,KIAA0319,PRICKLE2,IPCEF1,PCK2,IQGAP3,RRAS2,KIAA1211,ATP2B1,DLGAP1,MICAL2,HNF4G,NR4A1,GRID1,MARS,ARHGAP32,FNDC3A,MAP1B,RERE,GPR37,DPY19L2,FAT4,MPP7,THSD7B,SLC7A5,UACA,KIAA0513,ZNF808,FILIP1 |
| 1.835e-05 | -10.91 | EGF | smart domains | SM00181 | 183 | 40 | 9493 | 1056 |
TENM1,CELSR1,CELSR3,CNTNAP3,LRP4,LDLR,LAMC3,SELL,GAS6,BCAN,NRXN1,DNER,HMCN1,EFEMP1,NELL2,FRAS1,VWDE,SCARF2,ATRNL1,LRP6,PROS1,NTNG1,SLIT2,PCSK6,VLDLR,C1R,F12,HEG1,FAT4,FBN1,ITGBL1,FAT1,CCBE1,THBS4,LAMB1,MATN2,BMP1,EGFL7,PCSK5,TLL2 |
| 1.838e-05 | -10.90 | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP | 191 | 38 | 17377 | 1707 |
BCL11B,ENO2,SIDT1,IL32,RNF144A,GALNT12,ITGA6,GATA3,PRKCA,KIF21B,CD7,IL18R1,HOPX,NELL2,ABLIM1,TGFBR3,ALDOC,NAP1L3,BNIP3,SP140,PJA1,PTPRCAP,RRAS2,RWDD2A,COL6A2,PRKCQ,SKAP1,PLEKHB1,CAMK2N1,SLC39A14,BACH2,INPP4B,SERPINI1,TBC1D4,MLLT3,SMYD3,NR3C2,DOCK9 |
| 1.840e-05 | -10.90 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 184 | 37 | 17377 | 1707 |
MYO1D,TNIK,NMNAT3,HEBP1,ATP8A1,LMCD1,PLXNA2,ADD2,SPIRE1,EPDR1,TGFBR3,CA2,GPR155,EHD3,WWC2,C15orf41,KIAA1211,CTH,EPB41L5,BCL7A,ATL1,MYLK3,AGPAT4,CYTH3,GDPD1,STRADB,CENPV,SNCA,ZNF266,KIAA0355,PRCP,CECR2,TUFT1,ALG11,GRB10,HK1,SLC43A1 |
| 1.859e-05 | -10.89 | AAAYWAACM_V$HFH4_01 | MSigDB lists | AAAYWAACM_V$HFH4_01 | 234 | 44 | 17377 | 1707 |
BCL11B,C1QTNF3,FGF13,GRIK2,CADM2,TJP1,DOCK3,EPHB1,HMCN1,NEDD4,NEO1,FOXP2,EPB41L3,CHN2,RALGPS2,GRHL1,FLRT3,SLC10A7,BCL6,SGK1,TSPAN13,IQGAP3,SCN2A,NCAM1,HSPA2,GFRA1,DUSP1,BDNF,EVL,KLHL3,CRIM1,SLC39A8,PRDM1,FGF17,ATOH1,CLN5,IKZF3,KLF12,ITGBL1,MCC,PPARGC1A,MBOAT2,SEMA3A,MEF2C |
| 1.863e-05 | -10.89 | regulation of phosphate metabolic process | biological process | GO:0019220 | 1792 | 223 | 17256 | 1658 |
PHACTR3,ACSL1,PPP4R4,ACVR1,FGF13,DUSP8,GRIK2,DNAJC3,LDLR,NPM1,NDRG2,CEBPA,PRKCA,SNX9,STK24,GSDME,PPM1E,PPP1R26,TGFBR3,ZFYVE28,RAP2A,ITGB3,PPP2R2B,EPHB6,RCAN3,TLR4,TSHR,ENO1,SLIT2,PRKACB,RASGRP1,PDGFRB,TNK2,SESN2,GCNT2,SPOCD1,CAP2,TGFA,LRRK2,DEPTOR,PRKAR2B,ACVR2B,ROR1,INHBC,ENPP1,GPRC5B,SH3RF1,NCKAP1L,ERN1,ADRB1,TNFRSF1A,DIRAS1,INPP5F,SPRY4,NRP1,PPARGC1A,MAGI2,CACUL1,MEF2C,PRKAA2,TYRO3,LATS2,FN1,ITGA6,SLK,UBASH3B,SORBS3,TNFRSF10C,PFN2,TNFRSF19,MECOM,DDIT4,IGF1R,MYC,FLRT3,C1QL4,LRP6,INAVA,ADCY6,GPR161,NOS3,HMGCR,BOD1,PAK1,FGFR4,GPR176,ATP5IF1,MSTN,VLDLR,DUSP9,STRADB,WWC1,PDE8A,PLCB1,MAPKAPK2,PMEPA1,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,TESC,SFN,EPHA3,PRKN,ID1,NEK10,AVPI1,IL15,CELSR3,NTRK3,LCP2,PIBF1,TNKS1BP1,DDR1,PPP1R9A,TLR3,DACT1,CNKSR3,ACVR2A,DAB2IP,PDE4D,MET,HSPA2,IGFBP3,FZD1,FER,FZD4,PFKFB2,NOP53,PTPN6,ADCY1,PREX1,ATF3,WNT11,RARRES2,SYNJ2BP,CD40,MAGI3,FGFR1,SNCA,WARS,CAMK2N1,IRS2,SMAD3,RANBP2,CXCL10,NRG3,PTPRJ,GBP1,APELA,ITGA2,WWTR1,MAP3K21,DUSP19,TNFSF15,HGF,GRB10,BMPR1A,MAPK10,MID1,CNTN1,ARFGEF3,TENM1,TNIK,MYO1D,FARP1,NECAB2,BMPR2,EDA2R,PAK5,FZD8,IPO5,LRP4,HERC5,GAS6,P2RY1,PKN1,EPHB1,TPD52L1,BMP6,PPP2R3A,PRKCD,GHR,AFAP1L2,ERRFI1,IQGAP3,SMAD6,TNFRSF11A,SYK,SPRY2,PARP9,DUSP1,PFKFB4,MOB1B,VEGFC,VAV3,RAPGEF2,AGAP2,GAREM1,PHACTR2,CCNG1,RACK1,GUCY1A2,TLR6,DKK1,GPLD1,GPR37,PTPRC,TRIB3,NSD1,FGR,DOCK7,MYADM,MAP2K6,DLG2,LRRK1,BMP4,MAP3K20,ATP2B4,PKIA |
| 1.865e-05 | -10.89 | YATTNATC_UNKNOWN | MSigDB lists | YATTNATC_UNKNOWN | 354 | 60 | 17377 | 1707 |
MXI1,CCDC148,SORBS1,C1QTNF3,KIF5A,ZCCHC24,RASL11B,KCTD12,CEBPA,CTBP2,ADAMTS6,STAT5B,ZIC2,CREB5,SLC2A13,IKZF2,NOVA1,FOXP2,SOAT2,FRY,FLRT3,SAMD11,PRKG2,COL19A1,ACVR2A,JAKMIP2,BEND4,RTKN2,MARCKS,PPP2R2B,WWC2,MOXD1,GFI1,NEB,C15orf41,MN1,PRDM13,ANK2,FOXN3,PRICKLE1,SLITRK5,F12,FNDC3A,MBNL2,HOXA1,MAGI3,ZIC1,NAP1L5,NSD1,DOCK7,PTPRJ,GNAO1,NXPH4,DLG2,HOXB9,SEMA3A,NR3C2,KIF1B,SLC16A10,PCSK5 |
| 1.886e-05 | -10.88 | ion binding | molecular function | GO:0043167 | 6112 | 674 | 17224 | 1680 |
ARHGAP26,DOC2A,ADAL,PDE1B,TUBE1,BCAN,SNX9,CA8,EYA4,PCDH7,SKI,EPDR1,TGFBR3,IKZF5,DNAH6,RAP2A,RAB26,CPE,SMAD9,LRRK2,MSRB3,PRKAR2B,ABCC2,KCND3,F12,CA13,ENPP1,ZNF266,ATP7B,ZBTB20,ERCC5,DIRAS1,DNHD1,LPP,CRYL1,CARS,GNG12,LATS2,CYP2J2,ITGA6,SLK,ZNF25,HPCAL4,CHN1,APLF,ZIC5,LMAN2,CADPS2,LOXL4,ALPK1,DENND1C,MOXD1,FIGN,ZNF518B,GLIS1,CHRM3,ZNF385A,HMGCR,PNP,MYO10,EFHC2,ZNF605,FHL2,FASN,RYR2,HIP1,PLS1,C1R,ZBBX,MBNL2,CPEB1,DHX32,RIMKLB,ADAMTS3,QPCTL,CDH17,LAPTM4B,CDH2,TRPC3,GVINP1,CSRP2,MTG1,NUDT10,DNM3,ZNF516,GALNT12,GALNT6,MYO1B,MAPK4,GRK6,NRXN1,TXNRD3,RNF150,CHRNA5,KMO,COL25A1,PJA1,ARL4D,RAB27B,ZNF365,DNAH5,MYT1,SNX10,DZANK1,MYLK3,GARS,NECAB1,RNF145,PFKFB2,ADCY1,RAB38,ASPH,ZNF618,METAP1D,FGFR1,MAGI3,ENTPD1,CXCL10,PDLIM3,ZNF697,PEMT,PAM,RCN3,P4HA1,RAB30,GCAT,PLAG1,CBS,GAS6,P2RY1,CREB5,PKN1,EPHB1,ZNF219,COL27A1,MCF2L,MYO6,NPTXR,ZFP36L2,FES,PARP9,TRPM4,PDLIM7,OPLAH,CLYBL,RAB6B,RAPGEF2,RASA3,AK4,ATP11A,HEG1,GALNT3,TRIB3,ID3,NSD1,PCDHB7,PLOD2,AKT3,GNAO1,OSBPL5,NEK11,PIP5KL1,HK1,BMP4,CMPK2,ATP2B4,TPT1,PHC1,TLL2,NMNAT3,TRIM2,TRIM16,SYT12,LMCD1,ASS1,ITPR2,MGAT5B,SYT14,NUP62CL,FSTL5,PLS3,RND2,FKBP9,RUFY4,RPS6KA2,KCNAB1,AADAT,MPPED2,ENO1,ZNF391,ITGB7,KCNIP3,MARK1,ABCC4,ATOX1,GDPD1,PLEKHA1,SESN1,NT5DC2,DYRK1B,TRIM9,KLF12,P4HA2,ERN1,PIK3C2B,PXDC1,TC2N,RRAGD,PRKAA2,LONRF1,TYRO3,RUNX2,ZCCHC24,RASL11B,ZNF215,ZIC2,PFN2,HSPA12B,EFEMP1,RNF180,GALNT1,ZBTB38,PRTFDC1,IGF1R,ABCA5,BCHE,ZNF440,GATA2,FRAS1,PDE10A,HS3ST5,ADCY6,PAK1,CHSY3,FGFR4,MID2,SLC27A2,RNF170,MGAT4B,TCEA3,STRADB,OBSCN,PDE8A,LDHD,MAPKAPK2,PLD1,RNF122,TESC,PANK3,MME,PRKN,CFH,LPCAT2,ZNF83,RNF24,NTRK3,KIF21B,PCLO,DDX60L,CYP26A1,RIDA,ZNF362,IDI1,LHX6,MYO3B,BCL6,MYH15,CLVS2,ZNF488,SNAI2,GLI1,IGFBP3,CTH,TUBA1A,CSN2,PRDM13,ACO1,RNF125,CHRNA6,FRK,ETNPPL,SMAD3,RANBP2,RNF217,GBP1,PTK7,ITGA2,PTPRS,SEPT5,ZNF701,MAN2B2,TENM1,PCDH18,DYRK3,NECAB2,BMPR2,PAK5,NLRP14,MCTP2,SELL,RASD1,PRDM8,HBE1,ARHGAP44,PPP2R3A,FOXP2,TECPR1,RASD2,GTF2F2,SGK1,PRICKLE2,SH3PXD2B,KLF9,PCK2,SYK,ATP2B1,PCSK6,MOB1B,MICAL2,NUGGC,CRIP2,LITAF,NUAK2,FERMT2,PRICKLE1,EXOG,MGMT,SMPDL3B,EBF1,DDAH1,FAT4,L3MBTL4,FBN1,FMO4,ZNF214,ZNF474,ZNF808,THAP10,PTGES,KIF1B,CACNA2D1,ZNF235,MYCBP2,ACVR1,ATP8A1,LDLR,GATA3,ADAMTS6,PRKCA,RAC3,AARS,STK24,NCS1,TRPS1,MOK,ZFYVE28,GSTM3,SP140,PACSIN1,PLTP,GLDC,WISP3,NR6A1,ACVR1C,EFHC1,ACVR2B,GPC6,GNAI1,SH3RF1,CCBE1,PLK2,ENTPD7,BMP1,MAPK13,NRP1,SPOCK3,KLF8,ALOX5AP,CELSR1,ZHX3,SCN8A,DHCR24,OPHN1,SLC1A3,ADSSL1,CHD5,PRRG4,MECOM,ABLIM1,GBGT1,ADCK1,MSMO1,PRKG1,RUNDC3B,CPXM2,MAST4,RIMS2,RNF152,PLEKHA8,TBC1D8B,DCHS1,RAPGEF4,VLDLR,PACSIN3,NSD2,CDC42BPA,PLCB1,ZNF558,MMP15,DAGLA,PKN3,THBS4,MATN2,SQLE,SLFN5,SMYD3,AMPD1,ACSM3,PLA2G4A,EPHA3,RNF144A,RHOD,ZNF311,CHUK,NUDT12,DDR1,ZFYVE9,NELL2,ZNF827,SPEG,ASNS,ZNF438,DAB2IP,PDE4D,GAB2,PDK1,CYB5R2,PANK1,PREX1,NLGN4X,PRKCQ,ATP1B1,PYGO1,ATP10D,ISG20,SNCA,ZNF711,HTR7,ZNF396,IKZF3,POPDC3,TDO2,BEX3,PRKCB,MAP3K21,ZNF704,HPGD,KLF5,BMPR1A,MAPK10,NR3C2,MID1,MYO1D,PLSCR4,ATP9A,ARL2,KIF5C,INPP1,KDM7A,FTCDNL1,SOAT2,MGAT1,SGK3,PRKG2,PHYKPL,DYNC2H1,TBC1D9,SEPT3,SMAD6,GFI1,SMPDL3A,B4GALT6,PFKFB4,VAV3,PXN,GSTM2,ARHGEF28,ARAP2,CACNA1E,GUCY1A2,ZNF714,ZIC1,ZFP62,FGR,TERT,PCGF2,PGM2L1,LRRK1,B4GALT7,ATP1A3,NUDT17,ACSL1,MVK,KIF5A,JCHAIN,ABAT,DNER,IKZF2,HMCN1,GSDME,F3,ADPRHL1,TUBB4A,CYP51A1,PPM1E,ABI3BP,TRPC1,CNNM2,EPHB6,PCOLCE2,MYRIP,GALNT18,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,ATL1,TNK2,SESN2,CEMIP2,ZNF565,ROR1,SGK2,RNF44,GRK3,EML1,AK1,GSN,BCL11B,GPT2,MOCOS,FN1,ZNF395,BVES,SEC24D,RHOBTB1,STXBP6,RIMKLA,CYP4V2,YPEL2,GALNT13,SCD,CHSY1,PCDHB14,RNF141,EEF2,ZNF354A,CA2,EBF4,LIMCH1,RNF148,SNX7,ZNF629,NOS3,PCDH10,CDH26,HBG2,RHOQ,MSTN,PARD3B,GSTM4,EDEM3,GALNT17,PRDM1,LHPP,STEAP1,AMDHD1,PLAGL1,FCHO2,FAT1,RAB31,HK2,EGFL7,NEK10,ZSWIM5,CELSR3,PLEKHA5,COL18A1,MORC4,BCL6B,LACC1,CANX,SP8,SCIN,ZSCAN5A,SETDB2,PDZD8,UNC13B,RPS6KL1,FABP6,ZNF521,ACVR2A,STEAP3,PROS1,MET,ZNF460,HSPA2,SP140L,GCA,ANTXR2,FER,TES,MVD,EFCC1,TTLL7,WARS,TPK1,BCL11A,ZNF569,ZNF93,LMLN,TRIM34,FAAP20,RNF130,CYP2U1,PSPH,MAST1,TNIK,ENO2,CLGN,ARL15,LRP4,CLSTN2,SLX1B,OVOL2,CHN2,GTSF1,PRKCD,EHD3,DSG2,ACTA2,TRIM3,MARCH3,RRAS2,TNFRSF11A,FKBP14,USP2,RAB3B,KDM5B,HNF4G,ESRRG,NR4A1,CYTH3,OGDHL,ASAP3,PRRG1,MARS,AGAP2,ARHGAP32,ZFPM2,GALNT14,PEAK1,LRAT,RERE,ADAMTS17,RND3,MAP2K6,KIF21A,GEM,RNF157,MMP16,MAP3K20,ABCG1 |
| 1.904e-05 | -10.87 | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | 316 | 55 | 17377 | 1707 |
ACSL1,SIDT1,CLGN,CYP2J2,MLF1,UGDH,BLVRB,DHCR24,HERC5,IGF2BP2,SCD,FAM174B,SEL1L3,PCLO,SLC19A2,NEDD4,MTUS1,CYP51A1,RNF141,IDI1,MSMO1,PMAIP1,KMO,SLC22A18,MYC,GHR,SREBF1,CADPS2,TSPAN13,LIMCH1,CERS4,VWA5A,RASGRP1,PRKACB,GPR161,LAMP3,HMGCR,QSOX1,ESRRG,FASN,AK4,PRKAR2B,PLEKHB1,BCL11A,PLAGL1,XBP1,INPP4B,RGS10,SH3BP4,PAM,P4HA1,MAOA,KLF5,MID1,FOXA1 |
| 1.925e-05 | -10.86 | CATTGTYY_V$SOX9_B1 | MSigDB lists | CATTGTYY_V$SOX9_B1 | 339 | 58 | 17377 | 1707 |
PCDH18,TRIM2,SLC6A9,KLHL13,NDRG2,PRDM8,ADAMTS6,SCD,MGAT5B,COLEC10,RADIL,CHN1,FOXP2,NUMBL,ZNF362,CDR2L,NAV1,KCNN2,PCBP4,LHX6,MPPED2,SRGAP1,ZNF521,ACVR2A,JAKMIP2,DAB2IP,MARCKS,LOXL4,EPHB6,NIPAL2,GFRA1,SEMA6C,DPYSL5,MN1,ATL1,TUBA1A,PNRC1,SLC39A8,VLDLR,PANK1,PRKCQ,PRDM1,PLEKHA1,FGFR1,MAP1B,BCL11A,ZNF711,FAT4,KPNA3,PLXDC2,GNAO1,B3GALT2,DLG2,HOXB9,MID1,KIF1B,FOXA1,PHC1 |
| 1.932e-05 | -10.85 | ATGAAGG,MIR-205 | MSigDB lists | ATGAAGG,MIR-205 | 150 | 32 | 17377 | 1707 |
DMXL2,GPM6A,INPPL1,SORBS1,ACSL1,RUNX2,ESRRG,LRRK2,SATB2,ST6GALNAC3,CUEDC2,CANX,FRK,PLCB1,CCNJ,TRPS1,CHN1,KLF12,NACC2,RBPMS2,TSC22D1,SQLE,DLG2,MARCKS,FAM84B,WWC2,FAM155B,ERRFI1,SEPT5,SEPT3,KIF1B,B4GALT6 |
| 1.942e-05 | -10.85 | V$ER_Q6_01 | MSigDB lists | V$ER_Q6_01 | 249 | 46 | 17377 | 1707 |
SLC6A9,FGF13,NDRG2,CREB5,OVOL2,DDR1,SATB1,IKZF2,TRPS1,PPM1E,CNTN4,LRRN1,PCBP4,CHRDL1,BCL6,SHF,FAM155B,FIGN,ZFP36L2,C15orf41,POU3F3,GLI1,NDUFA4L2,PXN,BNIP3L,WWC1,WNT11,SYNJ2BP,PRDM1,SKAP1,SPATA7,ZIC1,GNAI1,CD37,CLDN12,MAP2K6,ALDOA,ERN1,C1orf21,MCC,PAM,B3GALT2,DLG2,HOXB9,LIFR,MID1 |
| 1.961e-05 | -10.84 | CEBPG (CCAAT enhancer binding protein gamma) | protein interactions | 1054 | 26 | 11 | 17029 | 1718 |
CEBPB,ATF4,GTF2F2,KLF5,ATF3,CEBPA,DBP,BATF,CEBPD,DDIT3,BATF3 |
| 1.992e-05 | -10.82 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | 157 | 33 | 17377 | 1707 |
PRKAA2,CGN,SERINC5,CHCHD7,PLAG1,SELL,NDRG2,ADAMTS6,FAM117B,NELL2,ABLIM1,IGF1R,ANKFN1,TSC22D1,RAB27B,RCAN3,PRKACB,SLC40A1,VNN2,LRMP,EDEM3,SHISA2,ARHGAP32,AMIGO1,ZNF711,SPNS1,VPS37D,KIAA0355,TMOD2,ZBTB20,TANC2,APBA2,FILIP1 |
| 1.997e-05 | -10.82 | BRLZ | smart domains | SM00338 | 51 | 17 | 9493 | 1056 |
CREB3L2,CEBPB,HLF,ATF4,BACH2,JDP2,XBP1,NFE2L1,MAFB,ATF3,CEBPA,DBP,CREB5,BATF,CEBPD,DDIT3,BATF3 |
| 2.025e-05 | -10.81 | GO_ION_TRANSPORT | MSigDB lists | GO_ION_TRANSPORT | 1183 | 159 | 17377 | 1707 |
ACSL1,CACNG3,GRIK2,ATP8A1,LDLR,MCOLN3,SLC2A13,ITPR2,CACNB4,SLCO3A1,NCS1,SLC9A7,KCNAB1,KCNN2,AKAP7,SLC22A18,SLC16A2,PPFIA2,SLC10A7,SERINC2,KCNS3,CNNM2,TRPC1,SLC2A12,TMEM37,GPM6A,SLC3A2,KCNIP3,ABCC4,KLHL3,ANK2,JPH1,ATOX1,SLC25A28,ABCC2,KCND3,SGK2,CA13,SFXN1,SLC7A1,ENPP1,KCNMB4,ATP7B,BBC3,SLC9B1,PRKAA2,KCNV1,TMEM63C,SCN5A,SCN8A,GABRB2,SLC25A27,ATP6V1E2,SLC36A4,SLC1A3,APBA1,MLC1,MCOLN2,CA2,SLC30A4,SLC7A11,CACNB2,PRELID2,PRELID1,SLC16A9,SLCO4C1,NIPAL2,STXBP1,SLC37A1,KCNQ3,SLC27A2,SLC36A1,TTYH2,CALCRL,RYR2,SNAP25,NPC2,STEAP1,TMCO3,CACHD1,KCNK15,GRIK4,MFSD2A,SLC2A6,SH3BP4,TRPC3,PLA2G4A,ADD2,SLC7A2,SLC19A2,UNC13B,CHRNA5,SLC22A17,FABP6,STEAP3,SCN2A,ATP6AP1L,KCNB2,SCN3A,CSN2,LRRC8B,SLC39A8,SFXN4,CYB5R2,KCNH5,CHRNA6,ATP1B1,ASPH,ATP10D,GJC1,SNCA,SLC39A14,PRKCB,KCNG1,DENND5B,ANO10,SERINC5,SLC6A9,ATP9A,GABRG2,GABRR2,SLC12A6,GAS6,NDFIP2,SFXN3,KCNC4,MCU,LRRC55,KCNJ4,SCN1B,BHLHA15,SGK3,KCNMB3,SGK1,SLC6A15,SYK,ATP2B1,TMC7,TRPM4,SLC40A1,CACNA1E,GRID1,RASA3,ATP11A,PTPRC,OSBPL5,SLC7A5,SLCO5A1,GRIN2D,SLC22A15,SLC1A5,SLC16A10,DDIT3,CACNA2D1,ATP2B4,SLC43A1,ATP1A3,ABCG1,TPT1 |
| 2.034e-05 | -10.80 | MODULE_1 | MSigDB lists | MODULE_1 | 355 | 60 | 17377 | 1707 |
TYRO3,GNG12,FN1,CFH,IGFBP6,ITGA6,UGDH,LDLR,EPS8,SFXN3,GAS1,MTUS1,ABLIM1,TGFBR3,CFHR1,MYC,SMTN,BCL6,SGK1,SERPINH1,NCAM1,CPE,GATM,PDGFRB,IGFBP3,PDLIM7,DBN1,QSOX1,MICAL2,MSX1,CD55,COL6A2,PNRC1,CRIM1,NR4A1,CAP2,PTPN13,TES,FHL2,SMARCD3,ATF3,TMEM47,RARRES2,FGFR1,HEG1,PDLIM3,FBN1,FAT1,WFS1,WWTR1,LAMB1,RAB31,P4HA1,SVIL,SEMA3C,ZBTB20,DBP,GEM,TPM1,SLC43A1 |
| 2.051e-05 | -10.79 | cellular response to organic substance | biological process | GO:0071310 | 2310 | 278 | 17256 | 1658 |
CGN,ACVR1,PDE1B,DNAJC3,LDLR,GATA3,NPM1,CEBPA,STAT5B,SKI,FBXO32,TGFBR3,CHRDL1,TSHR,GLDC,GDAP1,SMAD9,NR6A1,LRRK2,FEZ1,PRKAR2B,AGO4,ABCC2,FGF17,ACVR2B,GNAI1,ENPP1,MAPK13,NRP1,MEF2C,LATS2,GNG12,INPPL1,GABRB2,ITGA6,TNFRSF10C,TNFRSF19,GAS1,RPL13A,FLRT3,MYC,SREBF1,GRIP1,NCAM1,STXBP1,CHRM3,EPB41L5,BDNF,STAT4,EFHC2,ARID5B,FASN,FHL2,CALCRL,RYR2,PLCB1,CPEB1,SH3GL2,PMEPA1,PELI2,SMYD3,EPHA3,IL13RA1,MAPK4,CHUK,ZFYVE9,PLPP1,TLR3,ASNS,KMO,DAB2IP,PDE4D,SNX10,DOCK8,GAB2,MYLK3,GAPDH,FZD4,ADCY1,SATB2,WNT11,ATF3,FGFR1,ISG20,SNCA,IRS2,CXCL10,WFS1,HPGD,TNFSF15,KLF5,BMPR1A,MAPK10,NR3C2,MID1,CGB2,PLSCR4,EDA2R,ROBO2,ESRP1,IPO5,GAS6,P2RY1,NEDD4,HMGCS1,BHLHA15,GHR,YBX3,ERRFI1,SMAD6,GFI1,SPRY2,ZFP36L2,VEGFC,TRPM4,PXN,GSTM2,PTPN13,RAPGEF2,GAREM1,RACK1,GPLD1,CEBPB,GALNT3,ID3,TRIB3,TERT,XBP1,BMP4,CMPK2,TNFRSF17,CERS1,BTRC,OCLN,ATP2B4,DDIT3,LARP1,ATP1A3,ACSL1,ASS1,LILRB1,ITPR2,F3,GSDME,PCOLCE2,TLR4,SLIT2,IL1RAP,PDGFRB,PRKACB,CYP1B1,ATF4,GCNT2,SESN2,YAP1,BATF,SESN1,GSN,INSIG1,MAP2,GNB4,ERN1,TNFRSF1A,OXTR,PPARGC1A,TNFSF4,MAGI2,RRAGD,PRKAA2,RUNX2,FN1,ATP6V1E2,MLC1,IL18R1,DDIT4,NUMBL,IGF1R,CA2,EEF2,ADCY6,LRP6,CEBPD,NOS3,FGFR4,PAK1,IL17RD,RHOQ,MSTN,EDEM3,PDE8A,BAIAP2,HERPUD1,MAPKAPK2,RIPOR2,CSF1,HEYL,RAB31,HK2,SH3BP4,PTPRN2,TESC,MME,CREB3L2,CXCR5,PRKN,ID1,SORBS1,IL15,RBFOX2,NTRK3,CANX,UNC13B,BCL6,ACVR2A,HSPA2,SNAI2,CTH,FER,EVL,UROS,PTPN6,FGF12,GSTO1,VIM,CD40,SMAD3,MSC,TRIM34,PTK7,GBP1,EIF4EBP1,ITGA2,RGS10,MAOA,HGF,LIFR,HEY1,IL32,BMPR2,LRP4,TNFSF13B,GABRG2,BMP6,NKX6-1,RAB11FIP5,STC2,PRKCD,GTF2F2,KLF9,IQGAP3,PCK2,TNFRSF11A,FKBP14,SYK,ATP2B1,DUSP1,MSX1,KDM5B,HNF4G,NR4A1,NUGGC,ESRRG,LITAF,FERMT2,MARS,TLR6,LRAT,LEPR,MGMT,FAT4,EDA,FBN1,MAP2K6,PAX9,TBC1D4,KIF1B,IL9R,CACNA2D1 |
| 2.060e-05 | -10.79 | V$HNF3B_01 | MSigDB lists | V$HNF3B_01 | 199 | 39 | 17377 | 1707 |
TYRO3,BCL11B,THOC5,ID1,RUNX2,FGF13,CHCHD7,CYP2J2,PLAG1,RIMKLA,EPHB1,LCP2,FOXG1,IKZF2,SP8,NEDD4,FOXP2,ZNF827,CHN2,KCTD15,SCARF2,ZNF521,ERRFI1,GFRA1,DUSP1,SSH3,GPM6A,NR6A1,PRDM1,ZFPM2,PLCB1,BAIAP2,ISG20,KLF12,PELI2,B3GALT2,PPARGC1A,OSBPL6,LPP |
| 2.066e-05 | -10.79 | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_DN | MSigDB lists | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_DN | 171 | 35 | 17377 | 1707 |
ARHGAP26,RUNX2,TTC39B,IL15,JDP2,COBLL1,CHSY1,HOPX,SOAT2,PIK3AP1,PMAIP1,RAP2A,MYO3B,CERS4,SNX10,ATP2B1,SMPDL3A,PNP,CLYBL,STAT4,TES,DSTN,PTPN13,ATOH1,PRDM1,MFSD6,DOCK5,SMPDL3B,GALNT3,PTPRJ,MYADM,CAB39L,GEM,ATG5,ATP2B4 |
| 2.066e-05 | -10.79 | NAGASHIMA_NRG1_SIGNALING_UP | MSigDB lists | NAGASHIMA_NRG1_SIGNALING_UP | 171 | 35 | 17377 | 1707 |
AVPI1,ID1,DUSP8,REL,LDLR,INPP1,PHLDA2,STK24,PMAIP1,GATA2,FLRT3,MYC,SGK1,CTTN,ZNF365,SNAI2,CTH,DUSP1,NR4A1,TES,C3orf52,FHL2,FERMT2,ATF3,PALLD,ISG20,IRS2,CEBPB,ID3,TUFT1,DLX2,GEM,DDIT3,FOXA1,SFN |
| 2.078e-05 | -10.78 | CHANG_CORE_SERUM_RESPONSE_DN | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_DN | 192 | 38 | 17377 | 1707 |
FAM171B,MXI1,ZCCHC24,LDLR,SCD,FAM198B,ZNF219,SATB1,DDX60L,IDI1,HMGCS1,SLC22A17,MSMO1,BCL6,TSC22D1,ERRFI1,ETV1,GATM,FADS1,SLC40A1,EIF4E3,SESN2,KDM5B,PNRC1,PTPRU,MVD,ARID5B,SESN1,GABARAPL1,GSN,INSIG1,IGIP,CSF1,BDH2,BBC3,SQLE,SVIL,MAGI2 |
| 2.086e-05 | -10.78 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP | 185 | 37 | 17377 | 1707 |
CXCR5,AVPI1,IL15,BLVRB,PPFIBP2,GTF2IRD1,SCD,CD7,IKZF2,COL14A1,SPIRE1,EPB41L3,FKBP9,RALGPS2,UNC13B,PIK3AP1,CDC14B,C1orf53,LRP6,ST8SIA1,TBC1D9,PAK1,EVL,TMEM65,CRIM1,GDPD1,CR2,RASA3,CALCRL,ATP10D,ISG20,EBF1,PTPRC,AKT3,FBRSL1,RAB30,CTNND2 |
| 2.086e-05 | -10.78 | GSE30083_SP3_VS_SP4_THYMOCYTE_UP | MSigDB lists | GSE30083_SP3_VS_SP4_THYMOCYTE_UP | 185 | 37 | 17377 | 1707 |
MXI1,STOX2,ID1,YPEL2,PSD3,CUEDC2,SATB1,CTNNA2,NEDD4,COL27A1,CCDC120,RND2,BCHE,SCN1B,MARCKS,CTTN,RAB27B,TMEM120B,SLC45A3,ZNF385A,ULBP1,TNK2,TUBA1A,ADM2,ABCC2,AMIGO1,ACVR2B,ZDHHC14,IFT81,NRG3,PLOD2,MPP2,UACA,MBOAT2,SPOCK3,PURG,SLC43A1 |
| 2.129e-05 | -10.76 | germ_cell_tumour | COSMIC cancer mutations | germ_cell_tumour | 877 | 123 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,PLXNA2,RHPN2,NPM1,CHUK,CEBPA,NTRK3,GRK6,PRKCA,DDR1,IKZF2,PCLO,STK24,TRPS1,RTN1,BAG3,SPEG,PPM1E,RPS6KA2,COL25A1,RPS6KL1,MYO3B,ACVR2A,MET,NEB,PRKACB,PDGFRB,FER,TNK2,MYLK3,ERGIC1,MARK1,PDK1,ACVR1C,ALDH1L2,ANK2,LRRK2,ZNF565,PRKCQ,PRKAR2B,ROR1,ACVR2B,SGK2,ASPH,TBC1D16,FRK,FGFR1,ZNF569,DYRK1B,SMAD3,PTPRJ,PRKCB,PLK2,PTK7,ERN1,BMP1,MAPK13,BMPR1A,SPRY4,CNTN1,MAST1,PRKAA2,LRFN5,TNIK,LATS2,DYRK3,INPPL1,BMPR2,SEC24D,UBAC2,ISYNA1,PKN1,EPHB1,KCNC4,IGF1R,ADCK1,PDE10A,PRKCD,SGK3,PRKG1,RALGAPA2,PRICKLE2,SGK1,MPDZ,ALPK1,SYK,LRP12,FES,MED12L,NOS3,PAK1,FGFR4,PCDH10,PTPN13,DCHS1,NUAK2,OBSCN,STRADB,CDC42BPA,NAALADL2,MAP1B,MAPKAPK2,KCNK15,TRIB3,FGR,TMEM237,FAT4,TERT,PKN3,PRCP,MAP2K6,AKT3,SRD5A3,OSBPL5,CDH17,MCC,NEK11,KIF1B,CACNA2D1,LARP1,FILIP1 |
| 2.146e-05 | -10.75 | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN | MSigDB lists | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN | 144 | 31 | 17377 | 1707 |
CXCR5,UST,EPHA3,FARP1,FGF13,IL15,ST14,LPCAT2,WLS,PTPN13,ST6GAL1,LITAF,SELL,ATP1B1,SEZ6L2,SNTB1,MGMT,MYADM,INSIG1,FCHO2,TACC2,AKT3,ALDOC,GPR155,MYO3B,MARCH3,TNFSF15,BEND4,PROS1,TANC2,RNF122 |
| 2.157e-05 | -10.74 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 250 | 46 | 17377 | 1707 |
UGT8,PLSCR4,TTC39B,EPS8,YPEL2,FAM102B,NDRG2,TJP1,GRK6,CA8,FAM174B,PHLDA2,DDIT4,PCDH7,ATXN7L1,PPM1E,FRY,SGK3,MPPED2,NBEA,CTTN,RAB27B,ARL4D,SLC45A3,MOB1B,ITGB7,ARAP2,KDM5B,MVD,CAP2,TGFA,PRKCQ,ST6GALNAC3,SERGEF,CA13,GPR150,HOMER3,BEX4,PTPRJ,AKT3,GNB4,TECPR2,PGM2L1,BBC3,FNBP1L,SLC43A1 |
| 2.167e-05 | -10.74 | AAGCACA,MIR-218 | MSigDB lists | AAGCACA,MIR-218 | 379 | 63 | 17377 | 1707 |
BCL11B,EFNB2,ACSL1,RUNX2,ANKRD13B,ROBO2,LGR4,GRIK2,JDP2,GALNT13,CADM2,NRXN1,KIF21B,FAM13A,GDPD5,SEMA6A,HECTD2,FHOD3,PPP1R26,RPS6KA2,CA2,FLRT3,PRKG1,ZDHHC23,MARCKS,STXBP1,ZNF518B,MED12L,GAB2,DBN1,GPM6A,KCNIP3,TBC1D8B,FZD4,FOXN3,SHANK2,PRKAR2B,PEX5L,SATB2,ATP1B1,C3orf70,GUCY1A2,MBNL2,HOXA1,GLCE,DCBLD2,GNAI1,HTR7,GALNT3,TRIM9,HLF,KLF12,FCHO2,GNAO1,PCGF2,SLCO5A1,SFMBT1,DLG2,HS3ST3B1,PLD5,PPARGC1A,MAGI2,LIFR |
| 2.188e-05 | -10.73 | positive regulation of neuron differentiation | biological process | GO:0045666 | 340 | 57 | 17256 | 1658 |
EPHA3,PRKN,NBL1,FN1,ROBO2,BMPR2,PTPRD,APBB1,PLXNA2,NTRK3,GDPD5,FOXG1,BMP6,PPP1R9A,NKX6-1,RND2,GATA2,SCN1B,BCL6,GRIP1,DAB2IP,FIG4,PACSIN1,SLIT2,IL1RAP,RIMS2,FES,FZD1,PAK1,BDNF,FZD4,RAPGEF2,VLDLR,SHANK2,FEZ1,ATOH1,AMIGO1,BAIAP2,FGFR1,MAP1B,NEGR1,DKK1,GPRC5B,PTK7,HEYL,SERPINI1,HGF,DLX2,BMP4,NRP1,SHOX2,MAGI2,COBL,FOXA1,SHTN1,CNTN1,MEF2C |
| 2.206e-05 | -10.72 | human chr7q21.11 | chromosome location | human chr7q21.11 | 18 | 8 | 26185 | 1967 |
HGF,SEMA3C,LOC101927356,SEMA3A,MAGI2,PCLO,CACNA2D1,GNAI1 |
| 2.215e-05 | -10.72 | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_UP | 105 | 25 | 17377 | 1707 |
ARHGAP26,PLA2G4A,CD55,LGR4,THSD4,COL4A4,WWC1,PHACTR2,GABARAPL1,DKK1,ABLIM1,BCHE,KMO,FAT1,MAGEA3,XBP1,FAM107B,FAM84B,MAGEA6,ERRFI1,TESC,FOXA1,PERP,CTH,CYP1B1 |
| 2.215e-05 | -10.72 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_4 | 105 | 25 | 17377 | 1707 |
SESN2,TUBA1A,NECAB1,FN1,PTPN13,C1orf226,FHL2,ASS1,MAFB,ASPH,PHLDA2,CA2,NCAM2,OPN3,SGK3,MAOA,CADPS2,PLD1,ZNF365,CPE,RAPGEF5,GFRA1,SLC45A3,KIAA1211,CYP1B1 |
| 2.217e-05 | -10.72 | regulation of phosphorus metabolic process | biological process | GO:0051174 | 1806 | 224 | 17256 | 1658 |
PHACTR3,ACSL1,ACVR1,PPP4R4,FGF13,DUSP8,GRIK2,DNAJC3,LDLR,NPM1,NDRG2,CEBPA,PRKCA,SNX9,STK24,GSDME,PPM1E,PPP1R26,TGFBR3,ZFYVE28,RAP2A,ITGB3,PPP2R2B,EPHB6,RCAN3,TLR4,TSHR,ENO1,SLIT2,PRKACB,RASGRP1,PDGFRB,TNK2,SESN2,GCNT2,SPOCD1,CAP2,TGFA,LRRK2,DEPTOR,PRKAR2B,ACVR2B,ROR1,INHBC,ENPP1,GPRC5B,SH3RF1,NCKAP1L,ERN1,ADRB1,TNFRSF1A,INPP5F,DIRAS1,SPRY4,NRP1,PPARGC1A,MAGI2,CACUL1,MEF2C,PRKAA2,TYRO3,LATS2,FN1,ITGA6,SLK,UBASH3B,SORBS3,TNFRSF10C,PFN2,TNFRSF19,MECOM,DDIT4,IGF1R,MYC,FLRT3,C1QL4,LRP6,INAVA,ADCY6,GPR161,NOS3,HMGCR,BOD1,PAK1,FGFR4,GPR176,ATP5IF1,MSTN,VLDLR,DUSP9,STRADB,WWC1,PDE8A,PLCB1,MAPKAPK2,PMEPA1,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,TESC,SFN,EPHA3,PRKN,ID1,NEK10,AVPI1,IL15,CELSR3,NTRK3,LCP2,PIBF1,TNKS1BP1,DDR1,PPP1R9A,TLR3,DACT1,CNKSR3,ACVR2A,DAB2IP,PDE4D,MET,HSPA2,IGFBP3,FZD1,FER,PDK1,FZD4,PFKFB2,NOP53,PTPN6,ADCY1,PREX1,ATF3,WNT11,RARRES2,SYNJ2BP,CD40,MAGI3,FGFR1,SNCA,WARS,CAMK2N1,IRS2,SMAD3,RANBP2,CXCL10,NRG3,PTPRJ,GBP1,APELA,ITGA2,WWTR1,MAP3K21,DUSP19,TNFSF15,HGF,GRB10,BMPR1A,MAPK10,MID1,CNTN1,ARFGEF3,TENM1,TNIK,MYO1D,FARP1,NECAB2,BMPR2,EDA2R,PAK5,FZD8,IPO5,LRP4,HERC5,GAS6,P2RY1,PKN1,EPHB1,TPD52L1,BMP6,PPP2R3A,PRKCD,GHR,AFAP1L2,ERRFI1,IQGAP3,SMAD6,TNFRSF11A,SYK,SPRY2,PARP9,DUSP1,PFKFB4,MOB1B,VEGFC,VAV3,RAPGEF2,AGAP2,GAREM1,PHACTR2,CCNG1,RACK1,GUCY1A2,TLR6,DKK1,GPLD1,GPR37,PTPRC,TRIB3,NSD1,FGR,DOCK7,MYADM,MAP2K6,DLG2,LRRK1,BMP4,MAP3K20,ATP2B4,PKIA |
| 2.228e-05 | -10.71 | GO_PROTEIN_LOCALIZATION | MSigDB lists | GO_PROTEIN_LOCALIZATION | 1721 | 219 | 17377 | 1707 |
EXPH5,UGT8,FGF13,GRIK2,KIF5A,VAMP8,GATA3,LILRB1,NPM1,NUP62CL,SNX9,RAC3,TRPS1,ADPRHL1,RND2,SEC16B,AKAP7,PMAIP1,RAP2A,RAB26,LIN7A,TMED9,CTTN,COG3,PACSIN1,TLN2,TLR4,MYRIP,CPE,TBC1D8,DBN1,ITGB7,GDAP1,KCNIP3,WLS,ANK2,EXOC6B,LRRK2,ACVR2B,PLEKHA1,GSN,TNFRSF1A,BBC3,DIRAS1,NRP1,APBA2,MAGI2,CHMP4C,PCSK5,RRAGD,LATS2,CELSR1,STXBP5L,SEC24D,RHOBTB1,TBC1D1,STXBP6,DHCR24,ATP6V1E2,RASL11B,APBA1,MLC1,BBS9,PGAP1,TTC30B,RPL13A,SPIRE1,PDZD7,RPS11,CACNB2,FRAS1,GRIP1,LRP6,CADPS2,LMAN2,STXBP1,RIMS2,RPS23,SNX7,MID2,RPL26,DISC1,RHOQ,PNP,PLEKHA8,TBC1D8B,RAPGEF4,VLDLR,TTC30A,RYR2,CALCRL,STRADB,OBSCN,PEX5L,HERPUD1,SPATA7,TBC1D2,TEX15,VPS37D,RPL28,FCHO2,WDR19,HK2,RAB31,SH3BP4,PTPRN2,CDH2,TESC,SMYD3,SIX2,NBL1,ID1,SCAMP1,AKAP5,RHOD,MSR1,PKP2,LCP2,CANX,NRXN1,PIBF1,TBC1D30,CBLN1,PCLO,ZFYVE9,SCIN,EPB41L3,REEP1,BCL6,ZDHHC23,MAP7,NBEA,STEAP3,MARCKS,POU2F2,ARL4D,RAB27B,RPL26L1,SNX10,ZNF365,KCNB2,RPS13,DPP10,PHLDB2,PTPRU,TRAM1L1,WNT11,CBY1,SYNJ2BP,RAB38,PYGO1,ATP1B1,TBC1D16,DSP,RANBP2,IFT81,KPNA3,PRKCB,ITGA2,MID1,RAB30,RPS20,TNIK,MXI1,TSPAN15,LRP4,IPO5,UBAC2,ARL2,KIF5C,RASD1,P2RY1,GAS6,TSPAN17,NEDD4,RPL34,RAB11FIP5,EHD3,RASD2,TRIM3,PRKG2,SH3PXD2B,DYNC2H1,MYO6,TBC1D9,RRAS2,SYK,RAB3B,MSX1,LCA5,RAB6B,RAPGEF2,RPL21,ZDHHC15,FERMT2,PRICKLE1,AGAP2,SKAP1,TLR6,ILDR2,RERE,HOMER3,RPL12,MYADM,MPP7,NACC2,FBN1,TERT,RND3,XBP1,MCC,DLG2,RPL4,HK1,BMP4,RPS12,GEM,TBC1D4,ABCG1 |
| 2.278e-05 | -10.69 | adenoma | COSMIC cancer mutations | adenoma | 2923 | 347 | 17385 | 1698 |
MYCBP2,TRIM16L,PLBD2,LANCL3,FLVCR2,PDE1B,GRIK2,AASS,CADM2,CHAC1,PRKCA,KIAA1217,PCDH7,TGFBR3,SLC16A2,SERINC2,ATRNL1,VWA5A,TSHR,TBC1D8,DCC,KLHL23,KLHL3,LRRK2,ELMOD1,EFHC1,ABCC2,TNS1,KCND3,INTS6,ENPP1,ZNF266,CCBE1,MAP9,B3GALT2,MAPK13,ERCC5,ZBTB20,DSEL,UNC5B,DNHD1,STOX2,INPPL1,FAM124A,CELSR1,PTPRD,GABRB2,CYP2J2,ITGA6,DHCR24,ISYNA1,WDFY4,FOXG1,MTUS1,NAV1,BNIP1,RALGPS2,CNTN4,FLRT3,PRKG1,SRGAP1,GRIP1,MPDZ,TOX,LMAN2,FAM155A,ZNF518B,PRR16,STXBP1,RIMS2,IGSF3,KCNQ3,RAPGEF4,DCHS1,TTYH2,SMARCD3,C1R,AIG1,TEX15,TMCO3,ADAMTS3,CECR2,CDH17,FBXO27,IQSEC2,DHCR7,ACSM3,EPHA3,RASAL2,ST14,OTX1,IL13RA1,DDR1,ZFYVE9,TIAM2,GPR15,EPB41L3,GPRIN1,KMO,POU5F1B,STARD4,SCRN1,NAP1L3,PDE4D,RAB27B,DNAH5,KCNB2,SCN3A,DOCK8,GAB2,B3GALT1,RNF145,NPM3,KCNH5,SHANK2,PANK1,ADCY1,PREX1,NLGN4X,CBY1,WNT11,DSP,ASPH,METAP1D,MAGI3,SLC39A14,ZNF711,IQCK,GYPC,PDLIM3,LAMB1,PAM,PLEKHG1,NR3C2,KCTD1,HACE1,FARP1,ANKRD13D,ROBO2,ATP9A,PLAG1,KIF5C,PSD3,CREB5,EPHB1,ZNF219,COL27A1,RGS17,LRRN1,AFF2,SGK3,SLC6A15,DYNC2H1,MED12L,B4GALT6,TMC7,MN1,ALDH2,SYNPO2,SH3BP2,CLYBL,CACNA1E,PTPN13,GUCY1A2,SKAP1,ZIC1,GPLD1,TERT,GNAO1,MCC,PIP5KL1,MYOM2,ATP2B4,CRISPLD1,TLL2,ATP1A3,EXPH5,CACNG3,UGT8,KIF5A,PTPN21,TNFAIP8L2,FAM13A,DNER,SLCO3A1,HMCN1,FSTL5,HPS1,MPPED2,COL19A1,TRPC1,JAKMIP2,TMEM132E,TLN2,PTPRE,ENO1,NEB,SLIT2,IL1RAP,GPM6A,SESN2,ABCC4,SPOCD1,CR2,ROR1,SGK2,TCERG1L,TCF7L1,GPRC5B,KLF12,MAP2,TECPR2,CCDC146,APBA2,MAGI2,TC2N,KCNV1,SV2B,RUNX2,FN1,RHOBTB1,CHCHD7,LAMC3,SETBP1,PHGDH,DOK5,FHOD3,HSPA12B,RNF180,GALNT1,NUMBL,ZNF354A,ABCA5,BCHE,SMTN,LRP6,LIMCH1,RNF148,FBXL2,NCEH1,CAND2,PAK1,CHSY3,FGFR4,UNC5C,PCDH10,IL17RD,BTNL9,GSTM4,TMTC4,EDEM3,SLITRK5,KHDRBS2,SLC46A3,NEGR1,NAP1L5,GRIK4,PLAGL1,FAT1,NXPH4,PLD1,DISP2,XKR4,MME,NEK10,CFH,CELSR3,TDRKH,SEZ6L2,DENND3,TNKS1BP1,PPP1R9A,PCLO,DOCK2,UNC13B,KAZN,ZDHHC23,EEPD1,ZNF521,MET,NTNG1,GLI1,SUSD3,PHLDB2,TDRD3,SLC39A8,RNF125,GSTO1,SYNJ2BP,CD40,TTLL7,DOCK5,FRK,ZNF569,SMAD3,MSC,ZNF93,LMLN,ABI3,PTPRS,HGF,DISP1,LIFR,CTNND2,SLC6A9,TSPAN15,ARHGEF11,APBB1,MCTP2,CMTM8,TNFSF13B,SSX1,CLSTN2,GABRG2,NOTUM,SFXN3,BMP6,FSD1,KCNJ4,TECPR1,PRKCD,EHD3,TRIM3,DHRS12,IPCEF1,SYK,TNFRSF11A,ATP2B1,CARD6,MICAL2,HNF4G,NR4A1,NUAK2,PRRG1,TLR6,ILDR2,HOMER3,MAP1B,EBF1,GPR37,FAT4,L3MBTL4,FBN1,THSD7B,KIF1B,MMP16,CACNA2D1 |
| 2.285e-05 | -10.69 | YGCANTGCR_UNKNOWN | MSigDB lists | YGCANTGCR_UNKNOWN | 118 | 27 | 17377 | 1707 |
LRFN5,ELOVL4,BMPR2,FGF13,SYT12,PRDM13,LSM11,ZDHHC15,PNMA6A,CADM2,PLEKHA1,SEZ6L2,EPHB1,NRXN1,IKZF2,NOVA1,NCS1,FGFR1,MAP1B,TRIM9,EPB41L3,KCNN2,TACC2,KCNS3,HGF,HS3ST3B1,GAB2 |
| 2.321e-05 | -10.67 | GO_PLASMA_MEMBRANE_ORGANIZATION | MSigDB lists | GO_PLASMA_MEMBRANE_ORGANIZATION | 200 | 39 | 17377 | 1707 |
TNIK,PLSCR4,FGF13,TSPAN15,PKP2,GAS6,P2RY1,SNX9,TSPAN17,EPB41L3,CACNB2,EHD3,RAP2A,RAB26,ZDHHC23,MAP7,LRP6,LIN7A,PRKG2,PACSIN1,STXBP1,KCNB2,DPP10,KCNIP3,RAPGEF2,ANK2,PACSIN3,ATP1B1,SKAP1,BAIAP2,MYADM,FAT4,FCHO2,RAB31,AHNAK2,TNFRSF1A,CDH2,FNBP1L,TESC |
| 2.327e-05 | -10.67 | GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | 165 | 34 | 17377 | 1707 |
EXPH5,LATS2,ACSL1,SCN8A,ARHGAP22,PSD3,HERC5,CHADL,DDX60L,MCOLN2,BAG3,RPS6KL1,CNKSR3,MAGEA3,SLC6A15,MARCKS,MAGEA6,ERRFI1,KIAA1549,RASGRP1,DUSP1,ARAP2,GJB2,STAT4,RAPGEF2,OGDHL,TTYH2,GALNT3,CCNA1,TNFSF15,OXTR,HS3ST3B1,GEM,LIFR |
| 2.327e-05 | -10.67 | GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | 165 | 34 | 17377 | 1707 |
PLA2G4A,PLAG1,DHCR24,LDLR,TDRKH,PRKCA,SNX9,PRRG4,MCOLN2,ATXN7L1,EPCAM,CPNE2,TGFBR3,IDI1,MSMO1,ATRNL1,ALPK1,SNX10,DOCK8,HMGCR,SKAP2,SLC27A2,DSTN,DNAJC6,CALCRL,EFHC1,RAB38,ZDHHC14,TIFA,XBP1,NCOA7,ZBTB20,RNF130,FNBP1L |
| 2.347e-05 | -10.66 | HALLMARK_HYPOXIA | MSigDB lists | HALLMARK_HYPOXIA | 193 | 38 | 17377 | 1707 |
MXI1,ENO2,KIF5A,BCAN,PRKCA,F3,DDIT4,ALDOC,STC2,ERRFI1,ENO1,IGFBP3,DUSP1,GCNT2,GAPDH,PDK1,PNRC1,TES,VLDLR,EFNA3,BNIP3L,AK4,SDC3,ATF3,FAM162A,ISG20,IRS2,P4HA2,ALDOA,PAM,HK2,P4HA1,HK1,PPARGC1A,HOXB9,CSRP2,DDIT3,RRAGD |
| 2.365e-05 | -10.65 | Axon guidance | KEGG pathways | hsa04360 | 174 | 36 | 7161 | 730 |
EPHA3,EFNB2,SEMA6B,BMPR2,ROBO2,PAK5,RHOD,PLXNA2,ENAH,EPHB1,PRKCA,SEMA6A,RAC3,ABLIM1,SEMA4F,SRGAP1,TRPC1,EPHB6,MET,NTNG1,SLIT2,SEMA6C,FES,DPYSL5,PAK1,SSH3,UNC5C,PDK1,DCC,EFNA3,GNAI1,SEMA3C,UNC5B,NRP1,TRPC3,SEMA3A |
| 2.365e-05 | -10.65 | Axon guidance | KEGG pathways | ko04360 | 174 | 36 | 7161 | 730 |
EPHA3,EFNB2,SEMA6B,BMPR2,ROBO2,PAK5,RHOD,PLXNA2,ENAH,EPHB1,PRKCA,SEMA6A,RAC3,ABLIM1,SEMA4F,SRGAP1,TRPC1,EPHB6,MET,NTNG1,SLIT2,SEMA6C,FES,DPYSL5,PAK1,SSH3,UNC5C,PDK1,DCC,EFNA3,GNAI1,SEMA3C,UNC5B,NRP1,TRPC3,SEMA3A |
| 2.411e-05 | -10.63 | cation channel complex | cellular component | GO:0034703 | 215 | 40 | 18223 | 1724 |
KCNV1,SCN5A,CACNG3,GRIK2,SCN8A,KCNC4,CACNB4,ABHD6,NOS1AP,MCU,LRRC55,KCNJ4,KCNAB1,SCN1B,CACNB2,KCNMB3,KCNS3,CTTN,PDE4D,SCN2A,HSPA2,SCN3A,KCNB2,TRPM4,DPP10,KCNIP3,KCNQ3,CACNA1E,RYR2,CATSPERE,AMIGO1,SNAP25,KCND3,HERPUD1,GRIK4,KCNMB4,KCNG1,GRIN2D,DLG2,CACNA2D1 |
| 2.462e-05 | -10.61 | HORIUCHI_WTAP_TARGETS_UP | MSigDB lists | HORIUCHI_WTAP_TARGETS_UP | 281 | 50 | 17377 | 1707 |
ARHGAP26,TRIM16,IL15,RECK,OLAH,ITPR2,LACC1,INPP1,HMCN1,BEX2,COL27A1,SIPA1L2,CHN2,TLR3,STC2,OPN3,TSC22D1,ACTA2,MARCH3,SLC2A12,LIMCH1,TNFRSF11A,RAPGEF5,KIAA1211,CEBPD,LAMP3,ATL1,MID2,GDAP1,SLC40A1,GCNT2,LRRC8B,PARD3B,FOXN3,TGFA,ARID5B,VLDLR,MAFB,ATF3,ACVR2B,CEBPB,ENTPD1,FBN1,PRCP,CSF1,PIK3C2B,TANC2,CRISPLD1,HEY1,LPP |
| 2.473e-05 | -10.61 | cytoskeleton organization | biological process | GO:0007010 | 1053 | 141 | 17256 | 1658 |
ARHGAP26,UGT8,FGF13,TUBE1,HDGFL3,NPM1,RAC3,PLS3,TUBB4A,ARHGEF10L,RND2,LRRC6,RAP2A,POF1B,CTTN,TLN2,PACSIN1,PDGFRB,DBN1,MARK1,CAP2,ANK2,DSTN,EFHC1,EML1,GSN,WIPF3,MAP2,NCKAP1L,PLK2,MAP9,ALDOA,TMOD2,TPM1,NRP1,DNHD1,FRMD5,INPPL1,RHOBTB1,SLK,OPHN1,SORBS3,GPSM2,PFN2,SPIRE1,FHOD3,ABLIM1,KIAA1958,NAV1,FRY,PRKG1,GAN,LIMCH1,FIGN,MAST4,FMNL2,EPB41L5,PAK1,DISC1,RHOQ,PARD3B,PACSIN3,OBSCN,HIP1,PLS1,CDC42BPA,BAIAP2,FAT1,CECR2,IQSEC2,SHTN1,SORBS1,AMOTL1,RHOD,DOCK1,TMSB15A,GPR65,PSTPIP2,MYO1B,ADD2,PKP2,COBLL1,PIBF1,PCLO,SEMA6A,DOCK2,PPP1R9A,CTNNA2,SCIN,CCDC120,EPB41L3,PDZD8,CDC14B,TACC2,BCL6,MAP7,RTKN2,MARCKS,DNAH5,PHLDB2,FER,GAPDH,MYLK3,EVL,TUBA1A,PREX1,VIM,DSP,ARMC4,RANBP2,PTK7,SEPT5,COBL,MID1,MAST1,WASF3,TNIK,KIZ,ARHGEF11,PAK5,EPS8,ARL2,FSD1,MAP1A,GAS2L3,SEPT3,SPRY2,FES,PDLIM7,MICAL2,NUAK2,PALLD,MAP10,MAP1B,DOCK7,RND3,SVIL,MYOM2,JHY,NPHP1,MAP3K20 |
| 2.477e-05 | -10.61 | GO_DIGESTIVE_SYSTEM_DEVELOPMENT | MSigDB lists | GO_DIGESTIVE_SYSTEM_DEVELOPMENT | 145 | 31 | 17377 | 1707 |
EPB41L5,LGR4,NKX3-2,WLS,ITGA6,DCHS1,GATA3,ASS1,WNT11,PRDM1,ACVR2B,OVOL2,RARRES2,SAV1,TRPS1,SMAD3,FAT4,GATA2,DACT1,XBP1,WDR19,KLF5,HOXD13,OXTR,BMP4,SHOX2,BARX1,COBL,SIX2,PCSK5,GLI1 |
| 2.512e-05 | -10.59 | V$FOXJ2_02 | MSigDB lists | V$FOXJ2_02 | 215 | 41 | 17377 | 1707 |
PHACTR3,MXI1,TRIM2,ID1,BMPR2,FGF13,NRXN1,SATB1,NEO1,MECOM,EFEMP1,FRAS1,GHR,MPPED2,BCL6,ATRNL1,PDE4D,NKX2-1,USP2,TUBA1A,CRIM1,ACVR1C,ESRRG,DCHS1,NFIA,FEZ1,ATF3,SATB2,PRDM1,UCHL3,BCL11A,SLC39A14,GSTO2,KIAA0355,MAP2,INPP4B,DLX2,PPARGC1A,SEMA3A,LIFR,ATP2B4 |
| 2.515e-05 | -10.59 | actin filament organization | biological process | GO:0007015 | 227 | 42 | 17256 | 1658 |
WASF3,SORBS1,INPPL1,TMSB15A,RHOBTB1,RHOD,EPS8,MYO1B,COBLL1,ADD2,SORBS3,RAC3,PPP1R9A,FHOD3,SPIRE1,PLS3,SCIN,RND2,FRY,POF1B,MARCKS,CTTN,PACSIN1,DBN1,MICAL2,EVL,RHOQ,DSTN,CAP2,PREX1,HIP1,PLS1,BAIAP2,GSN,RND3,FAT1,ALDOA,MYOM2,TMOD2,TPM1,COBL,SHTN1 |
| 2.530e-05 | -10.58 | CTTTAAR_UNKNOWN | MSigDB lists | CTTTAAR_UNKNOWN | 901 | 126 | 17377 | 1707 |
NBL1,SORBS1,CACNG3,TCP11L2,SYT12,LMCD1,CTBP2,ADAMTS6,SLC2A13,COLEC10,HMCN1,ZFYVE9,HECTD2,SIPA1L2,PPM1E,NELL2,ZNF362,PPFIA2,RPS6KL1,RAP2A,CHRDL1,NBEA,ATRNL1,DAB2IP,PPP2R2B,ZNF365,TMEM56,NKX2-1,DPP10,SSH3,GPM6A,ACVR1C,KCNH5,PRDM13,SHANK2,LRMP,MEF2B,PRKAR2B,PLEKHA1,ATOH1,RNF44,GNAI1,GJC1,TCF7L1,IKZF3,ITGBL1,MAP2,ENPP6,GNB4,KLF5,ZBTB20,PIK3C2B,INPP5F,DBP,UNC5B,PPARGC1A,MAPK10,NR3C2,MEF2C,GPR63,BCL11B,PCDH18,KLF8,INPPL1,CHCHD7,GCAT,STXBP6,PLAG1,OPHN1,CYP4V2,ATP6V1E2,ZIC2,SCD,FAM117B,CREB5,SLC1A3,ZNF219,TNFRSF19,FOXG1,PFN2,SATB1,PHLDA2,GRPEL2,PPP2R3A,NEDD4,MECOM,NKX6-1,FOXP2,CNTN4,PDE10A,GAN,OPN3,ERRFI1,NIPAL2,SMAD6,RIMS2,FES,EPB41L5,BDNF,PCDH10,AGPAT4,FOXN3,ESRRG,MGAT4B,PACSIN3,CALCRL,PDE8A,PEX5L,PRDM1,SKAP1,MBNL2,NAALADL2,MAP1B,C11orf45,RERE,CEBPB,MMP15,PMEPA1,PLXDC2,PELI2,LRRIQ3,MPP2,DLG2,SEMA3A,KIF1B,SNPH |
| 2.550e-05 | -10.58 | KRAS.600_UP.V1_UP | MSigDB lists | KRAS.600_UP.V1_UP | 259 | 47 | 17377 | 1707 |
DNM3,UGT8,TRIM2,KIF5A,CLSTN2,KIF5C,NTRK3,FAM174B,FOXG1,SATB1,DYNC1I1,CTNNA2,RTN1,SCN1B,LIMCH1,SLC6A15,SCN2A,FAM155B,GFI1,TLR4,ETV1,SPRY2,FMNL2,GLDC,PNMA2,VEGFC,CSN2,SH2D2A,EXOC6B,SNAP25,GPR19,DCBLD2,GPR37,HTR7,ITGBL1,TERT,PELI2,ITGA2,SLCO5A1,TNFSF15,HS3ST3B1,NRP1,MAPK10,SEMA3A,CTNND2,HEY1,RRAGD |
| 2.566e-05 | -10.57 | BOQUEST_STEM_CELL_DN | MSigDB lists | BOQUEST_STEM_CELL_DN | 208 | 40 | 17377 | 1707 |
EFNB2,DNM3,TRIM16,IL15,ST6GAL1,ITGA6,NRN1,LCP2,TPD52L1,IL18R1,SEMA6A,TBC1D30,MECOM,RPS6KA2,GATA2,MCF2L,DSG2,LHX6,TSPAN12,TSPAN13,TBC1D9,MET,PTPRE,MAST4,JAM2,MYRIP,RAPGEF5,PNP,MYO10,LRMP,RAPGEF4,SYBU,ISG20,WARS,ICA1,KIAA0355,PIK3C2B,FNBP1L,DOCK9,ABCG1 |
| 2.581e-05 | -10.56 | TATTATA,MIR-374 | MSigDB lists | TATTATA,MIR-374 | 274 | 49 | 17377 | 1707 |
UST,SCN5A,RUNX2,DUSP8,ZCCHC24,ARL15,BACE1,PLAG1,GATA3,CADM2,ABAT,FOXG1,NOVA1,NEO1,NUMBL,CNTN4,LRRN1,PRKCD,AFAP1L2,PDE4D,SMAD6,SPRY2,MED12L,PCDH10,MSX1,GPM6A,LCA5,PNRC1,CRIM1,TGFA,ESRRG,SYBU,PRDM1,TMEM47,RAB38,MBNL2,HOXA1,MKX,CEBPB,ZNF711,HLF,PMEPA1,MAP2,MAP2K6,ARHGAP28,PPARGC1A,IQSEC2,PKIA,LARP1 |
| 2.590e-05 | -10.56 | Transmission across Chemical Synapses | REACTOME pathways | R-HSA-112315 | 217 | 40 | 10287 | 971 |
GNG12,CACNG3,AKAP5,GRIK2,GABRB2,GABRG2,ABAT,GABRR2,SLC1A3,APBA1,PRKCA,CACNB4,KCNJ4,RPS6KA2,UNC13B,CHRNA5,BCHE,CACNB2,PPFIA2,LIN7A,ADCY6,GRIP1,MYO6,STXBP1,PRKACB,ALDH2,CACNA1E,ADCY1,CHRNA6,PPFIA4,SNAP25,PLCB1,GNAI1,GRIK4,PRKCB,GNB4,RASGRF2,MAOA,GRIN2D,CACNA2D1 |
| 2.599e-05 | -10.56 | regulation of actin filament bundle assembly | biological process | GO:0032231 | 89 | 22 | 17256 | 1658 |
PAK1,PRKN,PHLDB2,SYNPO2,EVL,PXN,ID1,GPR65,ASAP3,SORBS3,WNT11,PFN2,PPP1R9A,ARHGEF10L,SMAD3,PPM1E,ARHGAP28,SH3PXD2B,TPM1,NRP1,MET,TMEFF2 |
| 2.612e-05 | -10.55 | ATATGCA,MIR-448 | MSigDB lists | ATATGCA,MIR-448 | 201 | 39 | 17377 | 1707 |
DOC2A,SCN5A,DNM3,GRIK2,HECW2,PFN2,HECTD2,NAV1,KCTD15,CNTN4,IGF1R,SLC7A11,DACT1,AFF2,GAN,MPPED2,NBEA,ETV1,GPM6A,ANK2,VLDLR,PRKAR2B,ATP11A,MBNL2,BCL11A,GLCE,GNAI1,DAGLA,ZNF711,IRS2,RANBP2,BACH2,SH3GL2,KPNA3,MAP2K6,KLF5,VASH2,DOCK9,MEF2C |
| 2.616e-05 | -10.55 | GO_CATION_CHANNEL_COMPLEX | MSigDB lists | GO_CATION_CHANNEL_COMPLEX | 159 | 33 | 17377 | 1707 |
KCNV1,SCN5A,KCNIP3,CACNG3,KCNQ3,CACNA1E,SCN8A,RYR2,AMIGO1,KCND3,SNAP25,KCNC4,CACNB4,ASPH,NOS1AP,HERPUD1,MCU,KCNJ4,KCNMB4,KCNAB1,SCN1B,CACNB2,KCNG1,KCNMB3,KCNS3,DLG2,CTTN,PDE4D,SCN2A,HSPA2,CACNA2D1,KCNB2,SCN3A |
| 2.663e-05 | -10.53 | phosphorus metabolic process | biological process | GO:0006793 | 2148 | 260 | 17256 | 1658 |
ADAL,ACVR1,PDE1B,DUSP8,AASS,STAT5B,PRKCA,ABHD6,EYA4,STK24,MOK,TGFBR3,PALD1,SERINC2,NDUFB8,PPP2R2B,NKX2-1,SMAD9,ACVR1C,LRRK2,DNAJC6,HACD1,ACVR2B,FGF17,ENPP1,ENPP6,PLK2,RASGRF2,ALDOA,MAPK13,INPP5F,MEF2C,CRYL1,LATS2,INPPL1,PTPRD,SLK,ISYNA1,ADSSL1,TNFRSF19,ADCK1,PIK3AP1,MYC,PRKG1,ALPK1,NCAM1,MAST4,GFRA1,HMGCR,FADS1,PNP,PLEKHA8,FASN,CDC42BPA,PLCB1,PKN3,PELI2,MPP2,AMPD1,ACSM3,PLA2G4A,EPHA3,BTC,NUDT10,RASAL2,CHUK,MAPK4,GRK6,NUDT12,DDR1,CDS1,SPEG,PLPP1,TLR3,KMO,ALDOC,DAB2IP,PDE4D,SSH3,MYLK3,GAPDH,GARS,PDK1,ADM2,PFKFB2,KCNH5,PANK1,ADCY1,PRKCQ,WNT11,PXYLP1,ATP1B1,MAGI3,FGFR1,SNCA,IRS2,PRKCB,TDO2,PEMT,INPP4B,MAP3K21,BMPR1A,MAPK10,SERINC5,GAS6,PKN1,EPHB1,INPP1,HMGCS1,MGAT1,GHR,SGK3,PRKG2,FIG4,ZFP36L2,SMPDL3A,FES,PARP9,PFKFB4,HYKK,PTPN13,MPP1,AGPAT4,RAPGEF2,ELOVL3,RASA3,AK4,CTTNBP2NL,GUCY1A2,GPLD1,PTPRC,TRIB3,FGR,PLPPR2,AKT3,OSBPL5,SRD5A3,PGM2L1,NEK11,GRIN2D,PIP5KL1,HK1,BMP4,LRRK1,CMPK2,BTRC,NUDT17,NMNAT3,ACSL1,MVK,FGF13,PTPN21,UGDH,ABHD4,QPRT,PPM1E,RPS6KA2,AADAT,EPHB6,ENO1,TLR4,PTPRE,PDGFRB,RASGRP1,PRKACB,TNK2,MARK1,GDPD1,PLPP2,PLEKHA1,ROR1,SGK2,GRK3,NT5DC2,DYRK1B,AK1,ERN1,PIK3C2B,OXTR,TYRO3,PRKAA2,MOCOS,UBASH3B,ELOVL7,SCD,DOK5,PGAP1,EFEMP1,PRTFDC1,IGF1R,PDE10A,ADCY6,FAR2,FGFR4,PAK1,IL17RD,RHOQ,PODXL2,OBSCN,STRADB,DUSP9,PDE8A,LHPP,MAPKAPK2,MFSD2A,HK2,PTPRN2,PLD1,PANK3,NEK10,IL15,LPCAT2,NTRK3,LPIN3,PIBF1,IDI1,CDC14B,RPS6KL1,MYO3B,ACVR2A,FHIT,MDH1B,MET,IGFBP3,FER,PTPRU,MVD,PTPN6,FRK,ETNPPL,TPK1,PTPRJ,PTK7,ABI3,DUSP19,PTPRS,HGF,MBOAT2,PSPH,MAST1,TNIK,DYRK3,ENO2,BMPR2,PAK5,PPP2R3A,PRKCD,SGK1,IQGAP3,PCK2,SYK,DUSP1,PPP1R3D,OGDHL,NUAK2,PEAK1,SMPDL3B,MAP2K6,DLG2,MAP3K20 |
| 2.671e-05 | -10.53 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_DN | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_DN | 187 | 37 | 17377 | 1707 |
CXCR5,CCDC126,ZSWIM5,FARP1,UBASH3B,ST6GAL1,TBC1D19,TGFBR3,IGF1R,EOMES,GRHL1,RUNDC3B,TSPAN13,TOX,PACSIN1,MYO6,AGL,SMPDL3A,EPB41L5,PDK1,MPP1,CYTH3,PANK1,DNAJC6,LITAF,PRICKLE1,PHACTR2,ATP1B1,TRIB3,KCNMB4,PRKCB,WFS1,RGS10,DYNC2LI1,DHCR7,NR3C2,SLC43A1 |
| 2.671e-05 | -10.53 | GSE1460_DP_VS_CD4_THYMOCYTE_DN | MSigDB lists | GSE1460_DP_VS_CD4_THYMOCYTE_DN | 187 | 37 | 17377 | 1707 |
SCN5A,ZNF516,KIF5A,GPR65,ST6GAL1,PPFIBP2,SELL,NPM1,NDRG2,SFXN3,EPHB1,PRKCA,INPP1,BMP6,CD53,ABLIM1,SP140,PDE4D,ZNF365,RPS23,SP140L,SCN3A,MICAL2,EVL,CD55,ASAP3,PLEKHA1,COTL1,SMAD3,RPL12,PAM,GRB10,RPL4,TBC1D4,MLLT3,TPT1,HEY1 |
| 2.676e-05 | -10.53 | forebrain development | biological process | GO:0030900 | 366 | 60 | 17256 | 1658 |
TYRO3,BCL11B,MYO1D,SCN5A,GNG12,ROBO2,FGF13,OTX1,OPHN1,BCAN,FOXG1,GDPD5,CHD5,RAC3,PGAP1,SKI,FOXP2,NUMBL,EOMES,GATA2,TACC2,LHX6,PRKG1,LRP6,BNIP3,DAB2IP,DYNC2H1,SLIT2,POU3F3,GLI1,NKX2-1,RAX,MSX1,RAPGEF2,LRRK2,SLITRK5,FEZ1,SATB2,EFHC1,ATOH1,PLCB1,FGFR1,TSKU,DKK1,NRG3,DOCK7,FAT4,MFSD2A,GNAO1,LAMB1,PTPRS,DLX2,OXTR,BMPR1A,BMP4,NRP1,PPARGC1A,CDH2,SEMA3A,ATP2B4 |
| 2.759e-05 | -10.50 | JAEGER_METASTASIS_UP | MSigDB lists | JAEGER_METASTASIS_UP | 42 | 14 | 17377 | 1707 |
MAGEA12,DDAH1,ENPP1,FN1,PLOD2,TBC1D1,THBS4,EPS8,MAGEA3,SNAP25,NCAM1,MET,MAGEA6,MME |
| 2.825e-05 | -10.47 | PCDHGB1 (protocadherin gamma subfamily B, 1) | protein interactions | 56104 | 68 | 19 | 17029 | 1718 |
PCDH18,PCDH10,PODXL2,CELSR1,CELSR3,PTPRU,DCHS1,PKP2,USP30,TTC28,PCDH7,FAT4,PKN3,ATP7B,ADGRL1,PTPRS,FAR2,ATP2B4,CNTN1 |
| 2.839e-05 | -10.47 | TGCCTTA,MIR-124A | MSigDB lists | TGCCTTA,MIR-124A | 526 | 81 | 17377 | 1707 |
EPHA3,CGN,ACSL1,CELSR3,RNF144A,MORC4,KCTD12,MAPK4,SEMA6A,EYA4,TRPS1,CDR2L,TACC2,SLC10A7,REEP1,RAP2A,SERINC2,MAP7,ACVR2A,JAKMIP3,PTPRE,ETV1,MYRIP,SEMA6C,ANTXR2,MARK1,ABCC4,JPH1,ADCY1,COTL1,BACH2,NCOA7,P4HA1,MBOAT2,MLLT3,LPP,CNTN1,LONRF1,EFNB2,FARP1,RUNX2,FZD8,BACE1,ZCCHC24,DHCR24,SCD,CHSY1,ZNF219,BMP6,MECOM,NAV1,RALGPS2,CACNB2,OPN3,LRP6,KIAA0408,TOX,LIMCH1,SPRY2,PCSK6,B4GALT6,MYO10,KIAA1324L,LITAF,GRID1,FERMT2,RYR2,PALLD,MAP1B,GLCE,RERE,NEGR1,SUGT1,MYADM,PMEPA1,AKT3,C1orf21,RAI14,FNBP1L,OSBPL6,LARP1 |
| 2.874e-05 | -10.46 | GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 406 | 66 | 17377 | 1707 |
DUSP8,DNAJC3,NDRG2,NPM1,NTRK3,CEBPA,PIBF1,PPM1E,ZFYVE28,DACT1,CNKSR3,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,PTPN6,LRRK2,DEPTOR,ATF3,PRKAR2B,SYNJ2BP,SNCA,CAMK2N1,IRS2,SMAD3,ENPP1,RANBP2,PTPRJ,GBP1,WWTR1,DUSP19,GRB10,INPP5F,HGF,SPRY4,PPARGC1A,LATS2,UBASH3B,PKN1,MECOM,DDIT4,IGF1R,FLRT3,MYC,C1QL4,PRKCD,LRP6,ERRFI1,SMAD6,SPRY2,HMGCR,DUSP1,MSTN,DUSP9,DKK1,PTPRC,TRIB3,MYADM,PMEPA1,BMP4,LRRK1,TESC,SMYD3,SFN,PKIA |
| 2.901e-05 | -10.45 | cardiac ventricle development | biological process | GO:0003231 | 122 | 27 | 17256 | 1658 |
SCN5A,ACVR1,BMPR2,TMEM65,GATA3,PKP2,RYR2,SMARCD3,NSD2,WNT11,PRDM1,ZFPM2,SAV1,DSP,HEG1,TGFBR3,PTK7,HEYL,SEMA3C,BMP4,BMPR1A,TPM1,SMAD6,CPE,HEY1,FZD1,MEF2C |
| 2.917e-05 | -10.44 | positive regulation of GTPase activity | biological process | GO:0043547 | 407 | 65 | 17256 | 1658 |
ARHGAP26,RGS16,STXBP5L,RASAL2,TBC1D1,ARHGEF11,DOCK1,ITGA6,GPR65,ARHGAP22,OPHN1,RGS20,NTRK3,FAM13A,RGS7,SNX9,TBC1D30,DOCK2,TIAM2,ARHGAP44,SYDE2,TBC1D19,CHN1,ADPRHL1,SIPA1L2,RGS17,CHN2,SRGAP1,RALGAPA2,DAB2IP,TBC1D9,ERRFI1,DOCK8,RASGRP1,TBC1D8,VAV3,RIN2,ARAP2,TBC1D8B,RAPGEF2,LRRK2,ELMOD1,ASAP3,PREX1,RASA3,AGAP2,WNT11,ARHGAP32,RACK1,CD40,PLCB1,TBC1D16,TBC1D2,RANBP2,ARHGAP21,DOCK7,ADGRB3,NCKAP1L,GNAO1,ADRB1,RGS10,ARHGAP28,NRP1,TBC1D4,DOCK9 |
| 2.935e-05 | -10.44 | MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MSigDB lists | MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 202 | 39 | 17377 | 1707 |
CELSR3,PLAG1,BIK,KIF5C,IGF2BP2,KCNC4,SATB1,CBLN1,COL27A1,CDS1,KCNJ4,EOMES,CHRNA5,TFAP2A,HRK,SLC6A15,PLTP,SMAD6,MYRIP,NTNG1,SLC40A1,PTPRU,JPH1,TMTC4,WNT11,CCDC85A,ATOH1,SNTB1,GALNT14,CPEB1,P4HA2,ATP7B,NXPH4,PTPRN2,HOXD13,NEUROG2,FRMD5,SIX2,OCLN |
| 2.962e-05 | -10.43 | GO_CELL_CORTEX | MSigDB lists | GO_CELL_CORTEX | 231 | 43 | 17377 | 1707 |
STXBP6,EPS8,RGS20,ITPR2,GPSM2,SPINK5,PCLO,HMCN1,PPP1R9A,SPIRE1,NEDD4,SCIN,FRY,MARCKS,CTTN,MYO6,MYRIP,DBN1,PHLDB2,FER,USP2,PXN,MYO10,EXOC6B,MPP1,DSTN,CRIP2,FERMT2,PLS1,ARHGAP32,ASPH,SNCA,GSN,PLEKHH2,MYADM,GYPC,WIPF3,RAI14,SEPT5,FNBP1L,CTTNBP2,CDH2,COBL |
| 2.990e-05 | -10.42 | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | 160 | 33 | 17377 | 1707 |
ID1,CKAP2,ASS1,TPD52L1,SLC19A2,DDIT4,CPNE2,NAV1,PMAIP1,MYC,PRELID2,BNIP3,PROS1,ZNF365,PERP,ARAP2,SESN2,NR6A1,ESRRG,CCNG1,FAM162A,C9orf116,AK1,PLK2,PLXDC2,FAT1,EIF4EBP1,PTK7,ALDOA,HK2,P4HA1,ERCC5,LPP |
| 3.022e-05 | -10.41 | FN3 | smart domains | SM00060 | 149 | 34 | 9493 | 1056 |
EPHA3,TYRO3,ROBO2,FN1,PTPRD,EPHB1,COL14A1,NEO1,FSD1,SPEG,CNTN4,IGF1R,ABI3BP,ANKFN1,KIAA0319,EPHB6,NCAM1,FANK1,MID2,DCC,PTPRU,OBSCN,SDK1,FNDC3A,LEPR,TRIM9,PTPRC,PTPRJ,NCAM2,PTPRS,MYOM2,LIFR,MID1,CNTN1 |
| 3.031e-05 | -10.40 | sterol metabolic process | biological process | GO:0016125 | 129 | 28 | 17256 | 1658 |
PRKAA2,MVK,EBPL,CYB5R2,MVD,LDLR,VLDLR,DHCR24,CYP4V2,NFE2L1,CEBPA,NPC2,LEPR,CYP26A1,CYP51A1,IDI1,ERG28,HMGCS1,SOAT2,INSIG1,MSMO1,OSBPL5,SREBF1,SQLE,DHCR7,ABCG1,HMGCR,CYP1B1 |
| 3.036e-05 | -10.40 | GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_DN | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_DN | 181 | 36 | 17377 | 1707 |
NBL1,DNM3,DOCK1,AKAP5,ESRP1,LRP4,LRRC49,NTRK3,SCD,LCP2,PPP2R3A,NOS1AP,HOPX,EFEMP1,TMEM53,NELL2,SOAT2,ATRNL1,PRKG2,TRPC1,PJA1,VWA5A,JAM2,SLIT2,GLDC,PTCH2,GSTM2,NR6A1,STAT4,PEX5L,LEPR,DHX32,DCBLD2,PAM,PLD1,SPRY4 |
| 3.039e-05 | -10.40 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN | 174 | 35 | 17377 | 1707 |
CXCR5,LANCL3,ATP9A,GATA3,COBLL1,IKZF2,DOCK2,IL18R1,PGAP1,HOPX,CHN1,STARD4,FAM107B,PROS1,PJA1,ARL4D,HSPA2,ATP2B1,DUSP1,ATF4,PNP,TUBA1A,FZD4,NR4A1,AGPAT4,STAT4,ATF3,ST6GALNAC3,CEBPB,ENPP1,PLK2,PTPRS,NRP1,TBC1D4,ATP2B4 |
| 3.039e-05 | -10.40 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP | 174 | 35 | 17377 | 1707 |
MXI1,ITPRIP,ARHGEF11,CKAP2,UBASH3B,PRKCA,BBS9,DDIT4,SLC22A18,ALDOC,SLC10A7,FHIT,PDE4D,ZFP36L2,SP140L,DUSP1,VNN2,EIF4E3,TDRD3,EFHC2,TCEA3,AIG1,SKAP1,TTC28,ISG20,TMEM132B,IRS2,MPP7,PRKCB,PELI2,SUSD4,SMYD3,LPP,PCSK5,CRYL1 |
| 3.062e-05 | -10.39 | Cholesterol biosynthesis | REACTOME pathways | R-HSA-191273 | 24 | 10 | 10287 | 971 |
CYP51A1,IDI1,MVK,HMGCS1,MSMO1,MVD,DHCR24,SQLE,DHCR7,HMGCR |
| 3.063e-05 | -10.39 | TGTTTGY_V$HNF3_Q6 | MSigDB lists | TGTTTGY_V$HNF3_Q6 | 684 | 100 | 17377 | 1707 |
ACVR1,DUSP8,GRIK2,FHDC1,PLXNA2,STAT5B,CADM2,RBM11,IKZF2,SEMA6A,TRPS1,LGI2,RTN1,ZNF827,SIPA1L2,GRHL1,SLC16A2,CHRDL1,MPPED2,BCL6,NDUFB8,PDE4D,PPP2R2B,GAB2,GPM6A,MEIS2,KCNIP3,TUBA1A,PNRC1,NR6A1,LRMP,JPH1,NFIA,ATOH1,ZDHHC14,RNF44,JAM3,EML1,GPR150,BCL11A,TCF7L1,IKZF3,KLF12,ENTPD7,B3GALT2,KLF5,SEMA3C,MAPK10,PURG,MEF2C,CNTN1,BCL11B,TYRO3,MXI1,ANKRD13B,ZNF395,MCTP2,TJP1,CREB5,OVOL2,ARHGAP44,PPP2R3A,FOXP2,ATXN7L1,CHN2,ZIC5,SGK3,HS3ST5,MARCH3,SGK1,NCAM1,ERRFI1,FIGN,SMAD6,MAST4,DUSP1,NOS3,HNF4G,HOMER2,MGAT4B,PACSIN3,PEX5L,PRDM1,SNAP25,ARHGAP32,SKAP1,GPLD1,ZIC1,RERE,GPR37,NSD1,TERT,KIAA0355,AKT3,SVIL,EGFL7,DLG2,SEMA3A,ACSM3,DOCK9 |
| 3.087e-05 | -10.39 | protein localization to cell periphery | biological process | GO:1990778 | 185 | 36 | 17256 | 1658 |
TNIK,FGF13,TSPAN15,PKP2,GAS6,P2RY1,ARHGAP44,EPB41L3,CACNB2,RAP2A,EHD3,RAB26,ZDHHC23,MAP7,LRP6,PRKG2,LIN7A,RTKN2,PACSIN1,STXBP1,KCNB2,DPP10,KCNIP3,RAPGEF2,ANK2,DCHS1,SNAP25,ATP1B1,SKAP1,MYADM,FCHO2,TNFRSF1A,RAB31,CDH2,TESC,KIF1B |
| 3.109e-05 | -10.38 | regulation of phosphorylation | biological process | GO:0042325 | 1547 | 195 | 17256 | 1658 |
ACSL1,ACVR1,FGF13,DUSP8,GRIK2,DNAJC3,NPM1,NDRG2,CEBPA,PRKCA,SNX9,STK24,GSDME,PPM1E,TGFBR3,ZFYVE28,RAP2A,ITGB3,EPHB6,TLR4,SLIT2,PRKACB,RASGRP1,PDGFRB,TNK2,SESN2,GCNT2,TGFA,LRRK2,DEPTOR,PRKAR2B,ACVR2B,ROR1,INHBC,ENPP1,GPRC5B,SH3RF1,NCKAP1L,ERN1,TNFRSF1A,INPP5F,DIRAS1,SPRY4,NRP1,PPARGC1A,CACUL1,PRKAA2,TYRO3,LATS2,FN1,ITGA6,SLK,UBASH3B,SORBS3,TNFRSF10C,PFN2,TNFRSF19,MECOM,DDIT4,IGF1R,MYC,FLRT3,C1QL4,LRP6,ADCY6,INAVA,HMGCR,PAK1,FGFR4,MSTN,VLDLR,DUSP9,WWC1,STRADB,PDE8A,PLCB1,MAPKAPK2,PMEPA1,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,TESC,SFN,EPHA3,PRKN,ID1,NEK10,AVPI1,CELSR3,IL15,NTRK3,LCP2,TNKS1BP1,DDR1,PIBF1,PPP1R9A,TLR3,CNKSR3,DACT1,ACVR2A,DAB2IP,PDE4D,MET,HSPA2,IGFBP3,FZD1,FER,FZD4,PFKFB2,NOP53,PTPN6,ADCY1,PREX1,WNT11,ATF3,RARRES2,SYNJ2BP,CD40,MAGI3,FGFR1,SNCA,WARS,CAMK2N1,IRS2,RANBP2,CXCL10,NRG3,PTPRJ,GBP1,APELA,WWTR1,MAP3K21,DUSP19,TNFSF15,HGF,GRB10,BMPR1A,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,LRP4,IPO5,HERC5,GAS6,P2RY1,PKN1,EPHB1,TPD52L1,BMP6,PRKCD,GHR,AFAP1L2,ERRFI1,IQGAP3,SMAD6,TNFRSF11A,SYK,SPRY2,PARP9,DUSP1,PFKFB4,MOB1B,VEGFC,VAV3,RAPGEF2,AGAP2,GAREM1,CCNG1,RACK1,TLR6,DKK1,GPR37,PTPRC,TRIB3,NSD1,FGR,DOCK7,MYADM,MAP2K6,LRRK1,BMP4,MAP3K20,ATP2B4,PKIA |
| 3.117e-05 | -10.38 | regulation of cellular process | biological process | GO:0050794 | 10836 | 1116 | 17256 | 1658 |
ARHGAP26,THOC5,GRIK2,RECK,NPM1,CTBP2,CEBPA,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,CPE,POU3F3,EIF4E3,DCC,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,FGF17,INTS6,PYCR1,ZNF788P,ENPP1,WIPF3,MAP9,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,INPP5F,DIRAS1,TPM1,VASH2,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,TOX,CADPS2,FIGN,JAM2,ZNF385A,ARID5B,ZNF605,FHL2,FASN,HIP1,SHISA2,SNAP25,ARRDC4,TEX15,CLMN,LAPTM4B,HOXD13,CDH2,SHTN1,DOCK9,MTG1,TFCP2L1,ADD2,MAPK4,GRK6,PLPP1,TLR3,MAGEA3,ZNF365,MYT1,KIAA1549,FZD1,MYLK3,GAPDH,NECAB1,PFKFB2,ADM2,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,CXCL10,ARHGAP21,WFS1,APELA,LAMB1,LRRC27,RAB30,CGB2,CKAP2,BACE1,PLAG1,FZD8,ESRP1,CD276,BIK,UBAC2,PSD3,GAS6,EPHB1,ZNF219,BEX2,LRRN1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,VEGFC,LZTS3,RAB6B,RASA3,NSD1,NEK11,BMP4,ATP2B4,PHC1,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,FAM13A,RND2,RPS6KA2,ITGB3,TBC1D32,ENO1,RAPGEF5,ZNF391,DBN1,KCNIP3,MARK1,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,NFE2L1,CR2,SESN1,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,ADGRA3,NEUROG2,ADGRL2,TC2N,CACUL1,RRAGD,LONRF1,TYRO3,RUNX2,STXBP5L,LGALS3,SORBS3,ZNF215,ZIC2,PFN2,DOK5,FHOD3,SPIRE1,RNF180,NUMBL,ZBTB38,ZNF440,LRP6,ADCY6,MED7,VGLL4,DPYSL5,BTNL9,EFNA3,GPSM1,SLITRK5,MAFB,STRADB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,PLD1,SEMA3A,ID1,DOCK1,RHPN2,NTRK3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,ZNF362,BCL6,SNAI2,IGFBP3,RPS13,INTU,CSN2,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,PTPRJ,RNF217,PTPRS,MAOA,HGF,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,PAK5,KLHL13,MCTP2,PRDM8,RASD1,USP30,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,TSPAN13,SYK,PCSK6,DUSP1,FOXN3,CRIP2,FERMT2,PRICKLE1,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,CD37,DDAH1,DOCK7,FBN1,SLC1A5,PTGES,PKIA,ZNF235,LGR4,LDLR,VAMP8,PRKCA,TRPS1,TYMP,ZFYVE28,KCNS3,ACVR1C,WISP3,BNIP3L,EFHC1,GNAI1,SH3RF1,BMP1,SERPINI1,MAPK13,SPRY4,NRP1,SPOCK3,KLF8,MRC2,TBC1D1,MLF1,DHCR24,TNFRSF19,GAS1,MTUS1,IL17D,RALGPS2,NOVA2,MYC,C1QL4,SREBF1,PRKG1,GRIP1,MAST4,PRR16,GPR161,BOD1,PTCH2,RPL26,DISC1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,PLEKHH2,PELI2,THBS4,WDR19,DYNC2LI1,MPP2,SFMBT1,DHCR7,SMYD3,NBL1,TCTN2,RHOD,PLXNA2,MSR1,TMEM170B,DDR1,TIAM2,ZFYVE9,SPEG,ASNS,ZNF438,POU5F1B,SHF,PDE4D,GAB2,SHANK2,PREX1,NLGN4X,ATF3,CBY1,SATB2,ATP1B1,PYGO1,ATOH1,ISG20,SNCA,PATJ,ZNF711,IKZF3,BEX3,CCNA1,ZNF704,HPGD,BMPR1A,MID1,PURG,COBL,STON2,HACE1,MYO1D,IGFBP6,EPS8,HERC5,NDFIP2,TPD52L1,INPP1,PHLDA2,ADGRB2,GSAP,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,SLC40A1,VAV3,SH3BP2,PXN,ARHGEF28,GSTM2,PTPN13,HOXA1,ZFP62,TERT,MCC,SVIL,LRRK1,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,F3,GSDME,ADPRHL1,EPCAM,SIPA1L2,PPM1E,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,OXTR,PPARGC1A,TNFSF4,MAGI2,FRMD5,GPR63,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,CHSY1,SPINK5,RNF141,EEF2,SLC30A4,ZNF354A,INAVA,CAND2,CEBPD,ZNF629,ATP5IF1,RHOQ,SLITRK2,HERPUD1,RIPOR2,PLAGL1,SH3BP4,RAB31,TMEM117,NXPH4,DISP2,FNBP1L,NKX2-8,SORBS1,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,FABP6,ACVR2A,FHIT,PROS1,SP140L,ALG10B,PRAME,ANTXR2,PTPRU,PTPN6,MVD,TCEAL3,AMIGO1,CD40,CENPV,ZNF569,BCL11A,BATF3,CAMK2N1,ARMC4,ZNF93,TRIM34,EIF4EBP1,RBPMS2,RGS10,DUSP19,MAST1,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,SLX1B,COL4A5,IGF2BP2,OVOL2,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,SCN1B,PRKCD,STC2,AFAP1L2,IPCEF1,TESPA1,PNMA2,CARD6,USP2,KDM5B,CRIM1,HNF4G,SYBU,ASAP3,TLR6,LEPR,CTIF,ICA1,EDA,RND3,ACER2,CTSV,UACA,IL9R,NPHP1,ABCG1,DOC2A,PDE1B,LSM11,DNAJC3,STAT5B,CHAC1,DOCK3,CA8,NOS1AP,EYA4,BAG3,TGFBR3,PPP1R26,PMAIP1,RAB26,TSHR,ZBED9,NKX2-1,MEIS2,SMAD9,TGFA,CAP2,WLS,F12,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,MEF2C,LATS2,GNG12,SLK,SYCP2,BNIP1,BACE2,ZIC5,ST8SIA1,NCAM1,TSPAN9,STXBP1,GLIS1,ZNF518B,FMNL2,GFRA1,CHRM3,LRP12,HMGCR,FADS1,BDNF,ENAM,PNP,MYO10,STAT4,CALCRL,SMARCD3,RYR2,PLS1,TAF4B,OR11H4,MBNL2,CPEB1,BEX4,SH3GL2,ADAMTS3,INHBE,CDH17,SPRED3,TRPC3,BTC,DNM3,ZNF516,TMSB15A,C4A,RGS20,PKP2,IL13RA1,LCP2,NRXN1,CDS1,TXNRD3,GPR15,EPB41L3,CHRNA5,KMO,DACT1,CNKSR3,RTKN2,RAB27B,PERP,DOCK8,SSH3,FZD4,KCNH5,NKX3-2,ATF7IP2,PXYLP1,RAB38,TTC28,FGFR1,IRS2,ZNF697,PEMT,GPR160,WWTR1,PLEKHG1,INPP4B,PAM,TNFSF15,DBP,KLHL31,HOXB9,FARP1,ROBO2,EDA2R,C1QTNF3,IPO5,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,NEO1,BHLHA15,MCF2L,MYO6,FES,BCL7A,CLYBL,RAPGEF2,MCF2L2,GAREM1,RACK1,PTPRC,GALNT3,TRIB3,ID3,PLPPR2,GNAO1,AKT3,XBP1,SHOX2,DOCK6,BTRC,FOXA1,TPT1,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,SYT14,NOVA1,EOMES,TCAF2,KCNN2,KCNAB1,TLR4,ETV1,NEB,ITGB7,CD55,GCNT2,PLPP2,PLEKHA1,TCERG1L,BATF,PLEKHB1,TSKU,INHBC,MAP2,GNB4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,UBASH3B,RASL11B,SETBP1,IL18R1,EFEMP1,KIAA1958,IGF1R,SEMA4F,GATA2,BCHE,ABCA5,PDE10A,BNIP3,FBXL2,FGFR4,PAK1,MID2,UNC5C,HOMER2,TCEA3,SPATA13,PDE8A,MAPKAPK2,CSF1,HEYL,TESC,SFN,SIX2,PRKN,AVPI1,AKAP5,RBFOX2,ZNF83,OR51B4,SLC7A2,LPIN3,PCLO,CBLN1,CTNNA2,CYP26A1,TBC1D19,RIDA,SLC22A17,LHX6,ADGRL1,SCN2A,ZNF488,CTH,GLI1,TMEM67,EVL,TUBA1A,NOP53,FGF12,GSTO1,RARRES2,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ABI3,ITGA2,KCNG1,SEPT5,ZNF701,CNTN1,LPAR2,IL32,GRB14,NLRP14,APBB1,GABRG2,ARHGAP44,PPP2R3A,MAP1A,RASD2,EIF1,PRICKLE2,KLF9,SH3PXD2B,PCK2,SLC45A3,MOB1B,MICAL2,PPP1R3D,NUGGC,NUAK2,LITAF,MAP10,MKX,TMEM237,FAT4,L3MBTL4,ZNF214,DLG2,ZNF808,MYRF,PAX9,THAP10,TBC1D4,CGN,MYCBP2,ACVR1,PPP4R4,LANCL3,DUSP8,ATP8A1,GATA3,RAC3,AARS,DACH2,STK24,NCS1,MOK,FAM168A,CFHR1,CHRDL1,ATRNL1,SP140,PACSIN1,RCAN3,TBC1D8,DCDC1,NR6A1,DNAJC6,DEPTOR,MEF2B,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,GPR150,AHRR,HLF,NCKAP1L,CCBE1,RASGRF2,PLK2,SEMA3C,UNC5B,SPART,ZBED8,LZTS1,EFNB2,INPPL1,CELSR1,ZHX3,PTPRD,GABRB2,SLC25A27,OPHN1,GTF2IRD1,TNFRSF10C,SLC1A3,CHD5,RPL13A,MYORG,MECOM,CNTN4,PIK3AP1,PRELID1,OPN3,TSPAN12,RIMS2,IGSF3,RNF152,EPB41L5,QSOX1,TBC1D8B,TCF24,PLCB1,ZNF558,FAM162A,DAGLA,PKN3,PMEPA1,IQSEC2,EPHA3,PLA2G4A,PCSK1N,AMOTL1,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,TBC1D30,ZNF827,STARD4,DAB2IP,MARCKS,SERPINH1,PDK1,SOX21,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,ATG5,MAPK10,NR3C2,KCTD1,WASF3,MXI1,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,KDM7A,RGS17,SGK3,RALGAPA2,PRKG2,FIG4,YBX3,GFI1,SPRY2,PFKFB4,SYNPO2,ARAP2,CACNA1E,MPP1,GUCY1A2,ZNF714,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,PCGF2,TUFT1,GRIN2D,OCLN,B4GALT7,EXPH5,HEBP1,TNFAIP8L2,JCHAIN,ABAT,RBM11,DNER,IKZF2,KREMEN1,ARHGEF10L,TUBB4A,GRHL1,AKAP7,DLX6,HRK,EPHB6,PCOLCE2,FANK1,PTPRE,OR2W3,SLIT2,RASGRP1,PRKACB,GPM6A,CAPN5,ZNF565,ROR1,SERGEF,GRK3,C8orf88,NCOA7,UST,BCL11B,FN1,JDP2,ATP6V1E2,CD7,SATB1,ADGRG6,DDIT4,CA2,EBF4,BARX1,NOS3,RAX,IL17RD,GPR176,MSTN,SH2D2A,EDEM3,WWC1,DUSP9,PRDM1,ADGRB3,HK2,EGFL7,CREB3L2,CXCR5,NEK10,ZSWIM5,CELSR3,IL15,BCL6B,DOCK2,SP8,ZSCAN5A,SETDB2,UNC13B,RPS6KL1,ZNF521,STEAP3,GULP1,MET,POU2F2,WWC2,ZNF460,HSPA2,DPP10,FER,PHLDB2,TES,SYNJ2BP,DOCK5,WARS,MSC,BACH2,SOHLH2,DISP1,LIFR,OR51B5,TNIK,REL,LRP4,CLSTN2,NOTUM,NKX6-1,CHN2,EHD3,DSG2,KIAA0319,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,GRID1,PHACTR2,AGAP2,MARS,CCNG1,ARHGAP32,ZFPM2,RERE,MAP1B,GPR37,TIFA,MYADM,GCSAM,MPP7,NACC2,MAP2K6,PRCP,GEM,MAP3K20 |
| 3.117e-05 | -10.38 | large_intestine-colon | COSMIC cancer mutations | large_intestine-colon | 1324 | 173 | 17385 | 1698 |
FAM171B,HEBP1,FHDC1,PPFIBP2,LILRB1,FAM102B,ABAT,BCAN,KIAA1217,ABHD6,HMCN1,F3,KCNAB1,ABI3BP,ANKFN1,ATRNL1,PCOLCE2,TMEM37,TLN2,MYRIP,OR2W3,FANK1,NEB,RASGRP1,PDGFRB,SMAD9,FAM84A,DNAJC6,NFE2L1,TCERG1L,CA13,EML1,AHRR,TMEM132B,SH3RF1,NCKAP1L,PLK2,MAP9,PIK3C2B,INPP5F,ZBTB20,SPOCK3,MEF2C,SEMA6B,KLF8,FN1,ATP6V1E2,SPINK5,FHOD3,FRY,CNTN4,PDZD7,ZNF440,FRAS1,OPN3,SMTN,DENND1C,FIGN,RIMS2,PNP,KCNQ3,PLEKHA8,COL4A4,PARD3B,HOMER2,VLDLR,RAPGEF4,DCHS1,PACSIN3,RYR2,HIP1,SLITRK5,TTYH2,SDK1,GRIK4,TEX15,TMCO3,RIMKLB,IQSEC2,FNBP1L,OSBPL6,DOCK9,EPHA3,EML5,RASAL2,DOCK1,GALNT6,LRRCC1,TDRKH,SLC7A2,KIF21B,DDR1,RADIL,PIBF1,DOCK2,CCDC120,COL22A1,ZNF438,GPRIN1,CNKSR3,COL25A1,LHX6,MYO3B,ZNF521,ACVR2A,NBEA,DAB2IP,NAP1L3,RTKN2,SCN2A,DNAH5,HSPA2,NTNG1,SNAI2,SCN3A,DPP10,TDRD3,PTPN6,CYB5R2,TES,PRDM13,PREX1,ATF7IP2,AMIGO1,TBC1D16,DSP,ARMC4,CCNA1,PAM,PTPRS,HGF,DBP,COBL,MYO1D,BMPR2,ROBO2,PRSS16,APBB1,GABRG2,PKN1,EPHB1,COL27A1,SLC35F1,IRX5,MAP1A,DSG2,AFAP1L2,MED12L,MN1,DLGAP1,MICAL2,ARAP2,GRID1,PHACTR2,ATP11A,SNTB1,ZFPM2,MAP1B,GPLD1,PTPRC,OR2T33,PCDHB7,FAT4,OSBPL5,MCC,SLCO5A1,NEK11,SVIL,KIAA0513,ZNF474,SLC22A15,KIF21A,ZNF235 |
| 3.118e-05 | -10.38 | DOANE_BREAST_CANCER_ESR1_UP | MSigDB lists | DOANE_BREAST_CANCER_ESR1_UP | 107 | 25 | 17377 | 1707 |
SSH3,VAV3,EVL,CELSR1,SIDT1,CLGN,SLC27A2,SYBU,CLSTN2,GATA3,ABAT,C9orf116,KCNK15,STC2,XBP1,C1orf21,INPP4B,SEMA3C,CERS4,MYO6,TBC1D9,TTC39A,MAST4,GFRA1,FOXA1 |
| 3.148e-05 | -10.37 | upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma-squamous_cell_carcinoma | 1513 | 194 | 17385 | 1698 |
EXPH5,MYCBP2,THOC5,PPP4R4,TUBE1,NPM1,CEBPA,SLC2A13,IKZF2,HMCN1,ANKRD42,RUFY4,SIPA1L2,HPS1,FAAH2,KCNS3,MPPED2,COL19A1,JAKMIP2,BEND4,TMEM132E,OR2W3,TLR4,ENO1,SLIT2,NEB,RASGRP1,ANK2,LRRK2,GDPD1,NFE2L1,DEPTOR,KCND3,CRYBG3,GPC6,ENPP1,INSIG1,MAP2,RASGRF2,TIGD4,DNHD1,FRMD5,LPP,MEF2C,LRFN5,SCN5A,ZNF395,FN1,CELSR1,ZHX3,SCN8A,ZNF25,SETBP1,TNFRSF10C,SATB1,BBS9,CHD5,EFEMP1,MCOLN2,BACE2,ZNF440,SAMD11,FAM155A,VGLL4,NOS3,QSOX1,TBC1D8B,SLC27A2,PARD3B,SPATA6,DCHS1,GPSM1,TMTC4,RYR2,TTC30A,OBSCN,SLITRK5,PEX5L,ZBBX,SDK1,GPR19,LDHD,NEGR1,GLCE,RIMKLB,MFSD2A,SLFN5,SEMA3A,NKX2-8,OSBPL6,DOCK9,DMXL2,EPHA3,NUDT10,NEK10,SORBS1,TCTN2,RASAL2,DOCK1,PSTPIP2,LRRCC1,PLXNA2,COBLL1,ZNF83,TNKS1BP1,PIBF1,COL14A1,PPP1R9A,PCLO,ZSCAN5A,ZNF827,COL22A1,PDZD8,SLC22A17,COL25A1,ALDH1L1,DAB2IP,MET,DNAH5,DOCK8,KCNB2,GLI1,VNN2,RNF145,PTPRU,KCNH5,SHANK2,VIM,WNT11,PYGO1,DSP,FGFR1,MAGI3,WARS,RANBP2,NRG3,IKZF3,IQCH,PTK7,INPP4B,ZNF704,PTPRS,SOHLH2,MAOA,KLF5,RNF130,CTTNBP2,MID1,COBL,DENND5B,OR51B5,PCDH18,ENO2,RUSC2,REL,EPS8,C1orf226,TNFSF13B,CLSTN2,KIF5C,SFXN3,RPL34,RAB11FIP5,KCNJ4,TECPR1,MAP1A,FUT9,DYNC2H1,NPTXR,TBC1D9,MED12L,TRPM4,DLGAP1,MICAL2,GSTM2,PXN,FOXN3,MEI1,RASA3,FERMT2,ZFPM2,NAALADL2,ZIC1,RERE,CTIF,NSD1,FAT4,TERT,ZNF214,MYOM2,PAX9,MMP16,PHC1,ZNF235 |
| 3.148e-05 | -10.37 | LIAO_METASTASIS | MSigDB lists | LIAO_METASTASIS | 487 | 76 | 17377 | 1707 |
FAM171B,GXYLT2,PLBD2,ST14,MCOLN3,C20orf194,ENAH,GRK6,PPP1R9A,TRPS1,ZNF827,ASNS,HPS1,SERINC2,TRPC1,TMED9,SERPINH1,RCAN3,KLHL29,DBN1,PDK1,RNF145,DNAJC6,TTLL7,ASPH,ZNF618,BCL11A,GPRC5B,POPDC3,MAP2,ALDOA,LAMB1,ITGA2,ZNF704,PAM,SEMA3C,MAPK13,NRP1,SUSD4,CTNND2,RRAGD,PCSK5,STOX2,FARP1,ENO2,RHOBTB1,PLAG1,ZIC2,IGF2BP2,FHOD3,MECOM,DDIT4,NUMBL,TECPR1,SLC7A11,GAS2L3,FIGN,VGLL4,CKAP4,IGSF3,PFKFB4,SLC36A1,DUSP9,MARS,SNAP25,PLCB1,MAP1B,DKK1,PLAGL1,TMEM237,SLC2A6,KIAA0513,TUFT1,SLC22A15,PLD1,PTGES |
| 3.172e-05 | -10.36 | GO_ANCHORING_JUNCTION | MSigDB lists | GO_ANCHORING_JUNCTION | 471 | 74 | 17377 | 1707 |
ARHGAP26,SORBS1,ARHGAP22,PKP2,NPM1,ENAH,CADM2,CTNNA2,KAZN,PPFIBP1,ITGB3,POF1B,MARCKS,CTTN,TLN2,PERP,PDGFRB,RPS13,FZD1,TNK2,PHLDB2,EVL,TES,CAPN5,VIM,TNS1,DSP,JAM3,GSN,LMLN,PTK7,ITGA2,OXTR,SPRY4,NRP1,CTNND2,LPP,EFNB2,MRC2,ITGA6,TJP1,SORBS3,RPL13A,RPS11,FLRT3,DSG2,EHD3,SCARF2,RRAS2,TSPAN9,FES,EPB41L5,PAK1,PDLIM7,SYNPO2,PXN,FHL2,ASAP3,FERMT2,SNTB1,PALLD,PEAK1,PTPRC,DOCK7,RPL12,MPP7,RND3,FAT1,SVIL,RPL4,CDH2,NPHP1,MME,CSRP2 |
| 3.176e-05 | -10.36 | GO_CARDIAC_CHAMBER_DEVELOPMENT | MSigDB lists | GO_CARDIAC_CHAMBER_DEVELOPMENT | 140 | 30 | 17377 | 1707 |
SCN5A,ACVR1,TMEM65,ANK2,FHL2,GATA3,PKP2,RYR2,SMARCD3,ADAMTS6,WNT11,PRDM1,OVOL2,ZFPM2,SAV1,DSP,HEG1,TGFBR3,PTK7,HEYL,SEMA3C,BMP4,TPM1,SHOX2,CPE,SMAD6,FZD1,HEY1,PCSK5,MEF2C |
| 3.185e-05 | -10.35 | Growth_fac_rcpt_cys_sf | interpro domains | IPR009030 | 127 | 28 | 18492 | 1811 |
EPHA3,TMEM67,IGFBP6,CELSR1,CRIM1,WISP3,LRP4,LDLR,KIAA1324L,GAS6,EPHB1,DNER,HMCN1,EFEMP1,NELL2,IGF1R,FAT4,FBN1,FRAS1,MATN2,BMP1,SCARF2,EGFL7,PROS1,EPHB6,PCSK5,PCSK6,IGFBP3 |
| 3.259e-05 | -10.33 | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | 254 | 46 | 17377 | 1707 |
FN1,IGFBP6,ST14,ESRP1,FHDC1,GATA3,ENAH,ISYNA1,GAS6,SFXN3,DDR1,PFN2,GAS1,SCIN,F3,TRPS1,EPCAM,FBXO32,ALDOC,STC2,BCL6,POF1B,ACTA2,ERRFI1,FIGN,PERP,TMEM56,MARK1,CSN2,GDPD1,WWC1,MAFB,COTL1,PALLD,DSP,PLEKHB1,GALNT3,ARHGAP21,RND3,PLK2,ZNF704,OCLN,FOXA1,ATP1A3,CNTN1,HEY1 |
| 3.349e-05 | -10.30 | KEGG_AXON_GUIDANCE | MSigDB lists | KEGG_AXON_GUIDANCE | 127 | 28 | 17377 | 1707 |
EPHA3,EFNB2,PAK1,DPYSL5,SEMA6B,UNC5C,ROBO2,RHOD,DCC,PLXNA2,EFNA3,EPHB1,RAC3,SEMA6A,GNAI1,ABLIM1,SEMA4F,SRGAP1,SEMA3C,EPHB6,UNC5B,NRP1,MET,SEMA3A,NTNG1,SLIT2,SEMA6C,FES |
| 3.360e-05 | -10.30 | DURAND_STROMA_NS_UP | MSigDB lists | DURAND_STROMA_NS_UP | 154 | 32 | 17377 | 1707 |
ARHGAP26,GPR176,LPAR2,ELOVL4,RAB6B,PTPN13,MLF1,GDPD1,TNFSF13B,WWC1,FEZ1,AIG1,CREB5,TMEM170B,KIAA1217,PLCB1,ABHD6,PRRG4,HECTD2,ICA1,CHN2,MPP7,MFSD2A,RUNDC3B,RALGAPA2,ATRNL1,SPRY4,UNC5B,SYNGR3,RAB27B,ZNF518B,JAM2 |
| 3.362e-05 | -10.30 | positive regulation of neurogenesis | biological process | GO:0050769 | 425 | 67 | 17256 | 1658 |
EPHA3,PRKN,NBL1,PLXNA2,NTRK3,SEMA6A,PPP1R9A,RND2,BCL6,DAB2IP,PACSIN1,ZNF488,ZNF365,SLIT2,IL1RAP,FZD1,FZD4,SHANK2,FEZ1,AMIGO1,ATOH1,FGFR1,GPRC5B,PTK7,HGF,SERPINI1,DLX2,NRP1,MAGI2,COBL,CNTN1,MEF2C,FN1,BMPR2,ROBO2,PTPRD,PLAG1,APBB1,FOXG1,GDPD5,BMP6,NKX6-1,NUMBL,SCN1B,GATA2,GRIP1,FIG4,FES,RIMS2,VEGFC,PAK1,DISC1,BDNF,RAPGEF2,VLDLR,SMARCD3,BAIAP2,MAP1B,DKK1,NEGR1,HEYL,CSF1,BMP4,SEMA3A,SHOX2,SHTN1,FOXA1 |
| 3.402e-05 | -10.29 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN | 189 | 37 | 17377 | 1707 |
DMXL2,MXI1,ACVR1,ACSL1,MRC2,RECK,PSD3,LCP2,SATB1,PFN2,NEDD4,RAB11FIP5,ABLIM1,EIF1,MPPED2,KCNS3,FHIT,PTPRE,TSPAN9,VGLL4,GAB2,PDLIM7,CRIM1,RAPGEF2,MPP1,RABAC1,BCL11A,AK1,WFS1,AKT3,SERPINI1,TNFSF4,COBL,ATP2B4,MME,SNPH,MEF2C |
| 3.402e-05 | -10.29 | GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP | MSigDB lists | GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP | 189 | 37 | 17377 | 1707 |
FGF13,BVES,RECK,FAM198B,LRRN1,RASD2,PRKCD,ZNF521,TSC22D1,LIMCH1,SMPDL3A,SLC40A1,ANTXR2,ITGB7,MID2,MSX1,EBPL,RAB6B,CRIP2,LRMP,HIP1,RASA3,MAFB,COTL1,SLC46A3,ARHGAP21,MYADM,PLOD2,PRKCB,PRCP,PTK7,SRD5A3,ADRB1,SVIL,CAB39L,RNF130,DBP |
| 3.412e-05 | -10.29 | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_UP | 161 | 33 | 17377 | 1707 |
UST,EXPH5,FGF13,RHOBTB1,BIK,ITPR2,DYNC1I1,TNFRSF19,ABHD6,CTNNA2,CDC14B,ALDH1L1,C1orf53,ANKFN1,RUNDC3B,SLC2A12,MYRIP,GFRA1,SNAI2,GSTM2,EBPL,PDK1,CAP2,ESRRG,VLDLR,TTC30A,GNAI1,HLF,THBS4,BMP4,SLC16A10,MME,ACSM3 |
| 3.413e-05 | -10.29 | CHEBOTAEV_GR_TARGETS_DN | MSigDB lists | CHEBOTAEV_GR_TARGETS_DN | 114 | 26 | 17377 | 1707 |
CHSY3,PLA2G4A,PHLDB2,VAV3,SOX21,ATP8A1,LRP4,DNAJC6,TCEA3,RASA3,COTL1,PALLD,CA8,CACNB4,PFN2,CPEB1,PDLIM3,TSC22D1,ZNF704,LIMCH1,CPE,FKBP14,PKIA,TMEM56,IGFBP3,CNTN1 |
| 3.433e-05 | -10.28 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_DN | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_DN | 182 | 36 | 17377 | 1707 |
GPR63,FN1,ARL15,APBB1,CREB5,PCLO,FHOD3,MECOM,MTUS1,RGS17,HPS1,KCNMB3,NBEA,GULP1,SLCO4C1,TNFRSF11A,NEB,ZNF391,TRDMT1,DZANK1,PFKFB4,UNC5C,B3GALT1,MEIS2,ABCC2,PLS1,NPC2,RARRES2,PEAK1,CRYBG3,BAIAP2,ZNF93,WWTR1,DYNC2LI1,ATP1A3,PHC1 |
| 3.433e-05 | -10.28 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN | 182 | 36 | 17377 | 1707 |
WASF3,PLSCR4,IGFBP6,FGF13,RBFOX2,PTPN21,MCOLN3,CANX,DOK5,GAS1,EFEMP1,NELL2,CPVL,SLC30A4,FRAS1,REEP1,PROS1,CPE,SLIT2,ATP2B1,EPB41L5,FER,GCA,CRIM1,CAP2,NFIA,TCEAL3,FERMT2,EFHC1,ZFPM2,TTC28,CRYBG3,DCBLD2,BEX4,TMEM237,KIF1B |
| 3.433e-05 | -10.28 | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_DN | MSigDB lists | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_DN | 182 | 36 | 17377 | 1707 |
EML5,TNIK,FLVCR2,FGF13,SYT12,ARL15,BACE1,CD7,KBTBD11,SLCO3A1,GPR15,EOMES,RUNDC3B,EPHB6,ARL4D,ENO1,TMEM120B,SMPDL3A,PRKACB,ITGB7,QSOX1,EVL,CRIM1,TGFA,STAT4,CYTH3,ZDHHC15,SPATA13,PREX1,RNF125,MFSD6,SKAP1,KCNMB4,PIP5KL1,TESC,AMPD1 |
| 3.440e-05 | -10.28 | GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN | MSigDB lists | GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN | 168 | 34 | 17377 | 1707 |
FN1,CFH,SEC24D,ZCCHC24,ST6GAL1,IL18R1,PPM1E,OTUD1,ZFYVE28,CDC14B,KMO,MGAT1,GPR155,TMEM86A,ALPK1,FAM84B,PCK2,GFRA1,PDGFRB,PRKACB,TRDMT1,VAV3,ITGB7,PRKCQ,AGAP2,VIM,ARRDC4,B3GALT2,DYNC2LI1,BDH2,FBXO27,AMPD1,DIRC2,SLC43A1 |
| 3.446e-05 | -10.28 | GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP | MSigDB lists | GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP | 175 | 35 | 17377 | 1707 |
TYRO3,NEK10,FARP1,MVK,PRSS12,RNF144A,LDLR,DHCR24,PKP2,NDRG2,FAM174B,KREMEN1,SPIRE1,TXNDC5,TXNRD3,RPS6KA2,MSMO1,PCBP4,PRELID2,STARD4,TSPAN12,PERP,FADS1,ERGIC1,EBPL,CLYBL,ALDH1L2,CRIP2,AK4,DCBLD2,INSIG1,HK1,PPARGC1A,DHCR7,OSBPL6 |
| 3.514e-05 | -10.26 | multicellular organismal signaling | biological process | GO:0035637 | 130 | 28 | 17256 | 1658 |
TRPM4,SCN5A,KCNIP3,CACNG3,GRIK2,SCN8A,ANK2,RYR2,PKP2,KCND3,ATP1B1,DSP,CACNB4,JAM3,GJC1,KCNJ4,KCNK15,KCNMB4,KCNN2,SCN1B,CACNB2,DSG2,KCNMB3,AHNAK2,SCN2A,SCN3A,CACNA2D1,ATP1A3 |
| 3.606e-05 | -10.23 | STK33_SKM_UP | MSigDB lists | STK33_SKM_UP | 255 | 46 | 17377 | 1707 |
STOX2,DUSP8,IL15,GPR65,SETBP1,HECW2,CREB5,SLC12A6,TTC30B,CD53,RTN1,RNF141,SYCP2,SIPA1L2,PRTFDC1,KIAA0895,SLC7A11,KMO,MPPED2,ACTA2,SGK1,MORN2,ERRFI1,ETV1,TBC1D8,DUSP1,EPB41L5,ARID5B,GDPD1,MAFB,SYNJ2BP,PALLD,TTLL7,ASPH,GPR137C,TLR6,FGR,MFSD9,FCHO2,RND3,MAP2,PLK2,WDR19,DYNC2LI1,TMOD2,FNBP1L |
| 3.610e-05 | -10.23 | cellular response to chemical stimulus | biological process | GO:0070887 | 2786 | 326 | 17256 | 1658 |
CGN,ACVR1,PDE1B,DNAJC3,LDLR,GATA3,NPM1,CEBPA,STAT5B,AARS,STK24,SKI,FBXO32,TGFBR3,PMAIP1,RAP2A,CHRDL1,GSTM3,TSHR,GLDC,GDAP1,SMAD9,NR6A1,LRRK2,BNIP3L,FEZ1,PRKAR2B,AGO4,ABCC2,FGF17,ACVR2B,GNAI1,PYCR1,AHRR,ENPP1,NCKAP1L,MAPK13,NRP1,TPM1,MEF2C,LATS2,SCN5A,GNG12,INPPL1,ALOX5AP,GABRB2,CYP2J2,ITGA6,TNFRSF10C,ADSSL1,TNFRSF19,GAS1,RPL13A,FLRT3,MYC,SREBF1,GRIP1,NCAM1,STXBP1,CHRM3,EPB41L5,BDNF,STAT4,MGST3,EFHC2,ARID5B,FASN,FHL2,CALCRL,RYR2,PLCB1,FAM162A,CPEB1,SH3GL2,GSTO2,PMEPA1,PELI2,SMYD3,EPHA3,PLA2G4A,IL13RA1,MAPK4,CHUK,ZFYVE9,TXNRD3,PLPP1,TLR3,ASNS,KMO,DAB2IP,PDE4D,SNX10,DOCK8,GAB2,MYLK3,GAPDH,PDK1,FZD4,PREX1,ADCY1,SATB2,WNT11,ATF3,PRKCQ,FGFR1,ISG20,SNCA,IRS2,CXCL10,WFS1,HPGD,TNFSF15,KLF5,BMPR1A,MAPK10,HOXB9,NR3C2,MID1,CGB2,PLSCR4,EDA2R,ROBO2,ESRP1,IPO5,GAS6,P2RY1,EPHB1,NEDD4,HMGCS1,BHLHA15,GHR,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,ZFP36L2,VEGFC,TRPM4,SLC40A1,VAV3,PXN,GSTM2,PTPN13,RAPGEF2,GAREM1,RACK1,GPLD1,CEBPB,GALNT3,ID3,TRIB3,TERT,XBP1,PCGF2,BMP4,CMPK2,CERS1,TNFRSF17,BTRC,OCLN,ATP2B4,DDIT3,LARP1,ATP1A3,ACSL1,LILRB1,ASS1,ITPR2,RBM11,F3,GSDME,PPM1E,CPNE2,PCOLCE2,TLR4,SLIT2,IL1RAP,PDGFRB,PRKACB,CYP1B1,SESN2,ATF4,GCNT2,NFE2L1,YAP1,PLEKHA1,BATF,SESN1,GSN,INSIG1,MAP2,GNB4,ERN1,TNFRSF1A,OXTR,PPARGC1A,TNFSF4,MAGI2,RRAGD,PRKAA2,RUNX2,FN1,LGALS3,ATP6V1E2,MLC1,PHGDH,IL18R1,DDIT4,NUMBL,EEF2,IGF1R,CA2,BCHE,ADCY6,LRP6,BNIP3,NCEH1,CEBPD,NOS3,FGFR4,PAK1,IL17RD,RHOQ,MSTN,GSTM4,EDEM3,PDE8A,BAIAP2,HERPUD1,MAPKAPK2,RIPOR2,HEYL,CSF1,SH3BP4,RAB31,HK2,PTPRN2,TESC,MME,CREB3L2,CXCR5,PRKN,ID1,SORBS1,IL15,RBFOX2,NTRK3,CANX,PPP1R9A,CYP26A1,UNC13B,BCL6,ACVR2A,HSPA2,SNAI2,CTH,FER,EVL,UROS,NOP53,PTPN6,FGF12,GSTO1,VIM,CD40,SMAD3,MSC,TRIM34,PTK7,EIF4EBP1,GBP1,ITGA2,RGS10,MAOA,HGF,CYP2U1,LIFR,HEY1,IL32,BMPR2,LRP4,TNFSF13B,GABRG2,BMP6,NKX6-1,RAB11FIP5,PRKCD,STC2,TFAP2A,GTF2F2,KLF9,IPCEF1,IQGAP3,PCK2,ESD,TNFRSF11A,FKBP14,SYK,ATP2B1,DUSP1,CES3,MSX1,KDM5B,HNF4G,NR4A1,ESRRG,NUGGC,LITAF,FERMT2,MARS,TLR6,LRAT,LEPR,MGMT,EDA,FAT4,FBN1,MAP2K6,ACER2,DLG2,PAX9,TBC1D4,KIF1B,IL9R,CACNA2D1 |
| 3.646e-05 | -10.22 | RIGGINS_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_UP | 65 | 18 | 17377 | 1707 |
FGFR4,ARHGAP26,TNIK,SLC27A2,GALNT6,ESRRG,MGST3,LRP4,ADCY1,FASN,PFN2,FGR,TGFBR3,SLC16A2,SPRY4,TPM1,PTGES,IGFBP3 |
| 3.675e-05 | -10.21 | pattern specification process | biological process | GO:0007389 | 410 | 65 | 17256 | 1658 |
NBL1,ACVR1,CELSR1,BMPR2,LRP4,OTX1,PLXNA2,CHSY1,OVOL2,FOXG1,PGAP1,SP8,SKI,NKX6-1,LRRC6,SETDB2,EOMES,TBC1D32,LRP6,ACVR2A,DYNC2H1,DNAH5,SMAD6,BARX1,PCSK6,GLI1,NKX2-1,EPB41L5,INTU,MICAL2,RAX,MSX1,WLS,NKX3-2,DCHS1,MAFB,SMARCD3,SATB2,ACVR2B,ASPH,ZIC1,DKK1,SMAD3,ARMC4,NRG3,WDR19,DYNC2LI1,PCGF2,SEMA3C,HOXD13,BMPR1A,DISP1,BMP4,DLX2,NRP1,SEMA3A,HOXB9,MID1,COBL,MLLT3,FOXA1,SIX2,DDIT3,PCSK5,MEF2C |
| 3.713e-05 | -10.20 | GGGTGGRR_V$PAX4_03 | MSigDB lists | GGGTGGRR_V$PAX4_03 | 1223 | 162 | 17377 | 1707 |
ARHGAP26,PHACTR3,ACVR1,DUSP8,FLVCR2,NDRG2,CADM2,KREMEN1,PLS3,LGI2,TUBB4A,CDR2L,ABI3BP,SLC16A2,PPFIA2,CHRDL1,JAKMIP2,EPHB6,PPP2R2B,NKX2-1,ITGB7,CD55,MEIS2,ANK2,CAPN5,NFE2L1,PRKAR2B,TNS1,KCND3,FGF17,ZDHHC14,SESN1,KLF12,NCAM2,GNB4,TIGD4,SERPINI1,SPRY4,RRAGD,HS6ST3,EFNB2,LRFN5,KLF8,ITGA6,SCN8A,DHCR24,RASL11B,ZIC2,APBA1,HPCAL4,HSPA12B,MTUS1,DDIT4,NUMBL,ZIC5,SCARF2,ST8SIA1,ZNF385A,IGSF3,NOS3,FGFR4,DPYSL5,MID2,SLITRK2,DCHS1,PRDM1,LDHD,NEGR1,MFSD2A,C1orf21,MPP2,HK2,INHBE,SIX2,NBL1,PCSK1N,RASAL2,BEGAIN,BCL6B,KCTD12,GRK6,SEZ6L2,RADIL,PRR7,TNKS1BP1,SEMA6A,ZNF827,SPEG,ZNF521,DAB2IP,PJA1,SEMA6C,FZD4,PTPN6,PRDM13,RNF125,VIM,RARRES2,FBXO36,FGFR1,ENTPD1,SLC39A14,MSC,BACH2,PTK7,EIF4EBP1,ITGA2,ABI3,KLF5,HOXB9,PURG,RAB30,CTNND2,HEY1,MXI1,FARP1,ANKRD13B,IGFBP6,BMPR2,ENO2,BLVRB,GABRG2,SLC12A6,OVOL2,EPHB1,TSPAN17,ARHGAP44,NEDD4,MAP1A,PCBP4,EIF1,TSPAN13,SEPT3,SMAD6,SPRY2,FES,RBMS2,MN1,PXN,USP2,RAB6B,CRIM1,NR4A1,FOXN3,AGPAT4,CACNA1E,FERMT2,ARHGAP32,ZFPM2,MAP1B,ID3,CD37,GNAO1,TUFT1,GRIN2D,DLG2,SH3BGRL2,BMP4,PTGES,FILIP1,PKIA,ATP1A3 |
| 3.767e-05 | -10.19 | RUIZ_TNC_TARGETS_UP | MSigDB lists | RUIZ_TNC_TARGETS_UP | 148 | 31 | 17377 | 1707 |
PNRC1,KDM5B,ATP9A,PTPN13,ZCCHC24,ARID5B,BNIP3L,COL18A1,MAFB,KCTD12,COL4A5,SNAP25,FAM110B,HERPUD1,GLCE,DDIT4,GSN,TDO2,PLK2,BDH2,BCL6,ARHGAP28,HPGD,SEMA3C,SLC6A15,KLF9,PROS1,VGLL4,ATP2B4,PDGFRB,HEY1 |
| 3.832e-05 | -10.17 | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | 190 | 37 | 17377 | 1707 |
LATS2,MXI1,FGF13,ST6GAL1,CYP4V2,SELL,RASL11B,GPSM2,ITPR2,SNX9,BBS9,SLCO3A1,RAB11FIP5,RPS6KA2,SLC30A4,KMO,BCL6,ADCY6,KLF9,RCAN3,PCK2,VEGFC,RAB6B,PARD3B,WLS,MPP1,CALCRL,ATP1B1,RAB38,ID3,TIFA,GPRC5B,LAPTM4B,SERPINI1,ZBTB20,DBP,MEF2C |
| 3.832e-05 | -10.17 | GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | MSigDB lists | GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | 190 | 37 | 17377 | 1707 |
CELSR1,ALOX5AP,ITGA6,ELOVL7,SORBS3,RNF24,ADSSL1,ABHD6,DOCK2,IL18R1,TRPS1,CACNB2,KAZN,MARVELD2,ALDH1L1,GHR,SLC16A9,TLR4,TRPM4,PAK1,VEGFC,ANTXR2,SKAP2,SFXN4,STAT4,SPATA13,CALCRL,PDE8A,CLN5,ENTPD1,PTPRC,PLXDC2,XBP1,PAM,CSRP2,LPP,ABCG1 |
| 3.842e-05 | -10.17 | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | MSigDB lists | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | 155 | 32 | 17377 | 1707 |
EML5,MYCBP2,ST6GAL1,SLC25A27,SELL,TDRKH,HMGCS1,TGFBR3,IGF1R,MYC,LRP6,ACVR2A,ADCY6,ST8SIA1,RRAS2,PDK1,WLS,RAPGEF4,PRRG1,TTC28,SESN1,MAGI3,IRS2,ID3,BACH2,RGS10,ZBTB20,RNF122,DIRC2,LARP1,AMPD1,CRYL1 |
| 3.869e-05 | -10.16 | MFS_trans_sf | interpro domains | IPR036259 | 135 | 29 | 18492 | 1811 |
SV2B,SLC40A1,SLC37A1,FLVCR2,MFSD13A,SLC2A13,MFSD6,SLC46A3,SLCO3A1,SLC19A2,SPNS1,MFSD9,SLC22A17,MFSD2A,SLC16A2,SLC22A18,SLC2A6,SLC18B1,SLCO5A1,SLC2A12,MFSD4A,SLC16A9,SLC22A15,SLCO4C1,SLC45A3,SLC16A10,DIRC2,OCLN,SLC43A1 |
| 3.877e-05 | -10.16 | MEK_UP.V1_UP | MSigDB lists | MEK_UP.V1_UP | 183 | 36 | 17377 | 1707 |
MYO1D,ACSL1,ENO2,FLVCR2,GALNT12,IGF2BP2,SLC7A11,BACE2,OPN3,CADPS2,LIMCH1,PTPRE,CYP1B1,TBC1D8,PDLIM7,MICAL2,ABCC4,PTPRU,CAPN5,PACSIN3,FERMT2,WNT11,NPC2,COTL1,ASPH,NT5DC2,CAMK2N1,PTK7,SLC2A6,RAI14,MAOA,CLMN,SIX2,PKIA,MEF2C,ABCG1 |
| 3.886e-05 | -10.16 | cell communication involved in cardiac conduction | biological process | GO:0086065 | 44 | 14 | 17256 | 1658 |
TRPM4,SCN5A,KCNN2,SCN1B,CACNB2,ANK2,DSG2,RYR2,PKP2,ATP1B1,DSP,CACNA2D1,GJC1,ATP1A3 |
| 3.888e-05 | -10.16 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN | 162 | 33 | 17377 | 1707 |
TNFAIP8L2,TNFSF13B,HERC5,LACC1,HERC6,TYMP,PRTFDC1,KIAA1257,GPR155,LHX6,MYO3B,MARCH3,TRPC1,LOXL4,FHIT,SP140,VWA5A,LAMP3,SNX7,INTU,DZANK1,BCL7A,SLC27A2,C3orf52,ATF3,PALLD,SGK2,ISG20,CXCL10,TMEM154,WWTR1,SH3BP4,PGM2L1 |
| 3.899e-05 | -10.15 | GO_PROTEIN_DOMAIN_SPECIFIC_BINDING | MSigDB lists | GO_PROTEIN_DOMAIN_SPECIFIC_BINDING | 613 | 91 | 17377 | 1707 |
TRIM16,AKAP5,DOCK1,GRIK2,RGS20,GATA3,LILRB1,ENAH,DOCK3,PPP1R9A,SKI,TGFBR3,KCNN2,ZNF521,LIN7A,ACVR2A,DAB2IP,POU2F2,SYNGR3,RAB27B,POU3F3,FZD1,TNK2,EVL,ATF4,TUBA1A,FZD4,PTPN6,DNAJC6,SHANK2,TCEAL3,ABCC2,PRKAR2B,PLEKHA1,SNCA,IRS2,GSN,WIPF3,ADRB1,CTTNBP2,MEF2C,SCN5A,MYO1D,GNG12,INPPL1,RUNX2,PLSCR4,FZD8,MLF1,BIK,TJP1,GABRR2,APBA1,NDFIP2,HPCAL4,NEDD4,KCNJ4,GATA2,CACNB2,AFAP1L2,SH3PXD2B,ERRFI1,STXBP1,ATP2B1,EPB41L5,DLGAP1,SH3BP2,RHOQ,SH2D2A,CRIM1,ESRRG,RAPGEF2,HOMER2,LITAF,SNTB1,SKAP1,KHDRBS2,BAIAP2,HOMER3,EBF1,ID3,ICA1,MPP7,PMEPA1,HEYL,SH3BGRL2,OCLN,SFN,ATP2B4,DDIT3,FOXA1 |
| 3.903e-05 | -10.15 | GO_CELL_JUNCTION_ORGANIZATION | MSigDB lists | GO_CELL_JUNCTION_ORGANIZATION | 176 | 35 | 17377 | 1707 |
UGT8,SORBS1,FN1,RHOD,ITGA6,PKP2,ARL2,TJP1,CADM2,PRKCA,EPB41L3,NUMBL,MARVELD2,DSG2,ITGB3,CTTN,TLN2,PERP,SNAI2,GJB2,ANK2,FERMT2,NLGN4X,WNT11,TNS1,DSP,GJC1,HEG1,SMAD3,MYADM,MPP7,ITGA2,CDH17,CDH2,OCLN |
| 3.919e-05 | -10.15 | establishment or maintenance of cell polarity | biological process | GO:0007163 | 187 | 36 | 17256 | 1658 |
UST,AMOTL1,FGF13,RHOBTB1,ARHGEF11,RHOD,OPHN1,GPSM2,EPHB1,DOCK2,RND2,RAP2A,SCARF2,MAP7,LIN7A,SPRY2,PAK1,MARK1,RHOQ,PARD3B,CAP2,CYTH3,WWC1,FEZ1,WNT11,JAM3,MAP1B,DOCK7,RND3,NCKAP1L,MPP7,MAP2,PTK7,FAT1,DLG2,SHTN1 |
| 3.982e-05 | -10.13 | GO_REGULATION_OF_CELL_MORPHOGENESIS | MSigDB lists | GO_REGULATION_OF_CELL_MORPHOGENESIS | 531 | 81 | 17377 | 1707 |
EPHA3,DNM3,ID1,FGF13,AKAP5,PLXNA2,NTRK3,RAC3,SEMA6A,TBC1D30,PPP1R9A,TBC1D19,RND2,EPB41L3,PDZD8,RAP2A,DAB2IP,MARCKS,CTTN,SLIT2,SEMA6C,TBC1D8,NKX2-1,SSH3,PHLDB2,GCNT2,DCC,LRRK2,PREX1,AMIGO1,TBC1D16,BCL11A,SMAD3,WIPF3,GBP1,ALDOA,WWTR1,SEMA3C,ATG5,NRP1,TPM1,LZTS1,UST,WASF3,TNIK,SEMA6B,BMPR2,ROBO2,FN1,TBC1D1,BVES,PTPRD,ST6GAL1,LRP4,EPS8,OVOL2,NEDD4,NKX6-1,CHN1,NUMBL,SEMA4F,SGK1,FMNL2,RIMS2,FES,EPB41L5,DISC1,BDNF,RHOQ,MYO10,RAPGEF2,FERMT2,BAIAP2,MAP1B,TBC1D2,FGR,MYADM,SHOX2,SEMA3A,CDH2,FOXA1 |
| 3.992e-05 | -10.13 | urogenital system development | biological process | GO:0001655 | 300 | 51 | 17256 | 1658 |
ROBO2,LGR4,PLAG1,ITGA6,LRP4,GATA3,ASS1,BMP6,EPCAM,RIDA,CA2,ZNF354A,GATA2,FRAS1,MYC,TFAP2A,ACTA2,SMAD6,SLIT2,POU3F3,PDGFRB,GLI1,COL4A3,SMAD9,KLHL3,COL4A4,DCHS1,LRRK2,ARID5B,NFIA,WNT11,ACVR2B,PYGO1,FGFR1,SMAD3,ID3,FAT4,FBN1,WFS1,HEYL,WWTR1,HPGD,HOXD13,BMP4,NRP1,MAGI2,FOXA1,MME,SIX2,PCSK5,MEF2C |
| 4.051e-05 | -10.11 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_UP | 371 | 61 | 17377 | 1707 |
FAM171B,PHACTR3,GNG12,MOCOS,TRIM2,DNM3,UGT8,CFH,SCAMP1,IL15,KLHL13,DNAJC3,PLAG1,MCTP2,HERC5,NRXN1,DYNC1I1,TNFRSF19,PHLDA2,FOXP2,GALNT1,PRTFDC1,SLC7A11,PMAIP1,VWDE,RAP2A,GHR,MPPED2,NCEH1,SLCO4C1,MYO6,FAR2,TNFRSF11A,FMNL2,GATM,RIMS2,LRP12,CHRM3,CEBPD,B4GALT6,ESRRG,PTPN13,SYBU,C3orf52,NFIA,SHISA2,PRKAR2B,CDC42BPA,MBNL2,SFXN1,POPDC3,MATN2,SQLE,KLF5,SERPINI1,CMPK2,VASH2,CTTNBP2,LIFR,TC2N,FOXA1 |
| 4.062e-05 | -10.11 | TMEM17 (transmembrane protein 17) | protein interactions | 200728 | 400 | 66 | 17029 | 1718 |
FAM171B,SCAMP1,RASAL2,AKAP5,PLEKHA5,VAMP8,PKP2,SLC7A2,SEMA6A,PCDH7,CYP51A1,PDZD8,PPFIBP1,MARVELD2,PALD1,NBEA,CNNM2,STEAP3,COG3,KIAA1549,SLC3A2,CEMIP2,JPH1,PLEKHA1,ROR1,SLC39A14,SLC7A1,PTK7,SPRY4,UNC5B,ADGRL2,TENM1,EFNB2,TNIK,SLC6A9,ITGA6,APBB1,GPR180,SLC12A6,SLC1A3,RAB11FIP5,SLC7A11,DSG2,LRP6,SLC6A15,SLCO4C1,ATP2B1,CKAP4,EPB41L5,B9D1,UNC5C,MPP1,PTPN13,HIP1,FERMT2,SHISA2,FNDC3A,CACHD1,TMEM237,MPP7,SLC7A5,RAI14,SLC1A5,OCLN,ATP2B4,STOM |
| 4.165e-05 | -10.09 | V$OCT1_B | MSigDB lists | V$OCT1_B | 249 | 45 | 17377 | 1707 |
REL,PLXNA2,KCTD12,CADM2,MGAT5B,NRXN1,FOXG1,HPCAL4,NEDD4,PPP2R3A,FSTL5,ZNF362,CDR2L,LRRN1,COL25A1,LHX6,RAB26,MPPED2,PRKG1,SLC6A15,BEND4,TSPAN13,PDE4D,ETV1,DNAH5,FES,GAB2,NDUFA4L2,BDNF,GPM6A,NR6A1,STAT4,FGF12,NFIA,SATB2,PRDM1,EBF1,ID3,GPRC5B,KLF12,MAP2K6,TMOD2,DLG2,MID1,TLL2 |
| 4.180e-05 | -10.08 | Ricin_B_lectin | pfam domains | PF00652 | 24 | 10 | 17054 | 1666 |
GALNT3,GALNT1,GALNT6,GALNT12,CRYBG1,GALNT17,GALNT13,GALNT14,GALNT18,CRYBG3 |
| 4.186e-05 | -10.08 | NAKAMURA_ADIPOGENESIS_LATE_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_LATE_UP | 96 | 23 | 17377 | 1707 |
XYLT1,NFIA,FASN,PRKAR2B,STAT5B,ATF3,SCD,GAS6,CCNG1,NOVA1,MGMT,IRS2,HMGCS1,TGFBR3,MYADM,INSIG1,MYC,PDE10A,RAB31,ACVR2A,NPTXR,CEBPD,STOM |
| 4.199e-05 | -10.08 | lung-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | lung-carcinoma-undifferentiated_carcinoma | 1421 | 183 | 17385 | 1698 |
ARHGAP26,THOC5,ACVR1,FGF13,STAT5B,PRKCA,DNER,KREMEN1,STK24,HECTD2,FBXO32,RPS6KA2,PMAIP1,RAP2A,PPP2R2B,TLN2,ETV1,TLR4,TSHR,PRKACB,PDGFRB,NKX2-1,DBN1,ACVR1C,TGFA,YAP1,PRKAR2B,ROR1,FGF17,ACVR2B,SGK2,SAV1,RNF44,TCF7L1,GPRC5B,SH3RF1,RASGRF2,TNFRSF1A,ADRB1,BBC3,MAPK13,ERCC5,PIK3C2B,DIRAS1,SPRY4,NRP1,TMEFF2,MAGI2,MLLT3,LPP,MEF2C,BCL11B,PRKAA2,CARS,LATS2,INPPL1,CELSR1,PTPRD,JDP2,MLF1,RASL11B,FOXG1,MECOM,SYCP2,NUMBL,OTUD1,IGF1R,MYC,LRP6,NOS3,PAK1,FGFR4,PTCH2,IL17RD,STAT4,HIP1,CALCRL,MAFB,DUSP9,STEAP1,MAPKAPK2,SQLE,EGFL7,HOXD13,PLD1,CDH2,SFN,CXCR5,EPHA3,PLA2G4A,BTC,CFH,RHOD,HECW2,CHUK,NTRK3,DDR1,RADIL,TLR3,BCL6,ACVR2A,MET,FZD1,IGFBP3,GAB2,PDK1,RNF145,FZD4,PTPN6,FGF12,ATF3,PRKCQ,WNT11,CD40,FGFR1,MAGI3,BCL11A,IRS2,RANBP2,NRG3,IKZF3,PRKCB,PTK7,EIF4EBP1,GRB10,BMPR1A,SEPT5,LIFR,CNTN1,HACE1,HEY1,LPAR2,BMPR2,IGFBP6,PLAG1,REL,FZD8,SSX1,TNFSF13B,HERC5,RASD1,P2RY1,PKN1,EPHB1,USP30,PPP2R3A,NEDD4,PRKCD,GHR,RASD2,SGK3,SGK1,RRAS2,SYK,SPRY2,TNFRSF11A,MED12L,DUSP1,PARP9,MN1,RIN2,VAV3,BCL7A,PPP1R3D,PXN,USP2,RAPGEF2,RASA3,UCHL3,GUCY1A2,TLR6,MGMT,DKK1,GPR37,RND3,GNAO1,AKT3,MAP2K6,BMP4,TNFRSF17,GEM,BTRC,DDIT3 |
| 4.205e-05 | -10.08 | cell-cell signaling | biological process | GO:0007267 | 1172 | 153 | 17256 | 1658 |
DOC2A,FGF13,LGR4,GRIK2,SYT12,KIF5A,GATA3,NDRG2,SYT14,CACNB4,NOVA1,RAC3,KREMEN1,KCNN2,PPFIA2,LIN7A,TSHR,CPE,MARK1,WISP3,WLS,ANK2,GJB2,LRRK2,AGO4,ACVR2B,ROR1,FGF17,GPC6,TRIM9,TCF7L1,KCNMB4,ADRB1,TMOD2,NRP1,APBA2,MAGI2,TC2N,MEF2C,PCSK5,EFNB2,PRKAA2,SV2B,SCN5A,CELSR1,GABRB2,TJP1,SLC1A3,APBA1,PCDHB14,SEMA4F,CACNB2,MYC,LRP6,CADPS2,STXBP1,BARX1,RIMS2,CHRM3,FADS1,PCDH10,GPR176,BDNF,DISC1,KCNQ3,RAPGEF4,EFNA3,PPFIA4,RYR2,SLITRK5,SNAP25,OR11H4,PLCB1,GPR19,DAGLA,GRIK4,FAT1,MPP2,SELENOM,PTPRN2,PRKN,AMOTL1,AKAP5,CELSR3,IL15,PKP2,GRK6,NRXN1,PCLO,CBLN1,PPP1R9A,UNC13B,CHRNA5,DACT1,SNAI2,GLI1,FZD1,FZD4,PTPRU,FGF12,CHRNA6,WNT11,PYGO1,FGFR1,GJC1,SNCA,HTR7,SMAD3,CXCL10,PTK7,KLF5,HGF,SEPT5,HOXB9,CTNND2,CGB2,TNIK,PCDH18,SLC6A9,FZD8,LRP4,GABRG2,NOTUM,SLC12A6,GABRR2,KCNC4,RAB11FIP5,SCN1B,BHLHA15,RASD2,KCNMB3,PRICKLE2,TNFRSF11A,DLGAP1,TRPM4,CACNA1E,GRID1,FERMT2,PRICKLE1,ILDR2,DKK1,PCDHB7,GNAO1,MCC,DLG2,GRIN2D,BMP4,KIF1B,BTRC,CACNA2D1,FOXA1,DDIT3,SNPH |
| 4.232e-05 | -10.07 | GO_NEURON_PROJECTION_GUIDANCE | MSigDB lists | GO_NEURON_PROJECTION_GUIDANCE | 198 | 38 | 17377 | 1707 |
BCL11B,EFNB2,ROBO2,CELSR3,KIF5A,OPHN1,PLXNA2,GATA3,KIF5C,ENAH,EPHB1,NRXN1,SEMA6A,NEO1,CHN1,CNTN4,SEMA4F,SCN1B,FLRT3,NCAM1,ETV1,SLIT2,SEMA6C,NKX2-1,DPYSL5,UNC5C,BDNF,EVL,DCC,EFNA3,FEZ1,PRKCQ,ATOH1,MATN2,SEMA3C,UNC5B,NRP1,SEMA3A |
| 4.236e-05 | -10.07 | organelle subcompartment | cellular component | GO:0031984 | 1653 | 203 | 18223 | 1724 |
ACSL1,ATP8A1,DNAJC3,ITPR2,CHAC1,MGAT5B,SNX9,ABHD4,CHST10,SLC9A7,NOS1AP,CYP51A1,RTN1,SEC16B,SLC10A7,RAB26,TMED9,COG3,GALNT18,RASGRP1,CYP1B1,ATL1,CD55,GCNT2,ERGIC1,WLS,TGFA,JPH1,LRRK2,LRMP,NFE2L1,HACD1,INSIG1,RASGRF2,ATP7B,ERN1,TNFRSF1A,B3GALT2,DSEL,UST,TYRO3,ALOX5AP,HID1,SEC24D,CYP2J2,ST6GAL1,DHCR24,ELOVL7,CYP4V2,SCD,GALNT13,CHSY1,SPINK5,PGAP1,MYORG,RNF180,GBGT1,GALNT1,BNIP1,ABCA5,MSMO1,FLRT3,SREBF1,HS3ST5,LMAN2,ST8SIA1,NCAM1,MOXD1,NCEH1,CKAP4,NOS3,HMGCR,CHSY3,FADS1,QSOX1,IL17RD,B3GLCT,SLC37A1,PLEKHA8,SLC27A2,RNF170,MGST3,MGAT4B,GPSM1,RYR2,ST6GALNAC3,GALNT17,SHISA2,SNAP25,B4GALNT3,HERPUD1,GLCE,SH3GL2,PMEPA1,MFSD2A,QPCTL,RAB31,SQLE,PLD1,DHCR7,OSBPL6,CREB3L2,PLA2G4A,PCSK1N,ELOVL4,SCAMP1,LPCAT2,GALNT12,GALNT6,XYLT1,MYO1B,RGS20,RNF24,FAM198B,CANX,LPIN3,SEZ6L2,CYP26A1,CDS1,ERG28,TLR3,PDZD8,ERO1B,REEP1,ZDHHC6,NBEA,PROS1,RAB27B,CLVS2,ALG10B,ANTXR2,B3GALT1,EVA1A,TMEM67,EBPL,LRRC8B,CYB5R2,TRAM1L1,C3orf52,RNF125,CBY1,PXYLP1,RAB38,ASPH,TRIQK,ATP10D,GJC1,ARHGAP21,GBP1,PEMT,WFS1,PAM,ALG11,HS3ST3B1,CYP2U1,MBOAT2,NR3C2,RAB30,RETREG1,HACE1,CLGN,BACE1,ATP9A,UBAC2,CLSTN2,NDFIP2,GSAP,RAB11FIP5,SOAT2,FUT9,MGAT1,SGK1,FIG4,CERS4,TESPA1,B4GALT6,RAB6B,AGPAT4,CYTH3,SYBU,ELOVL3,LITAF,ARHGAP32,FNDC3A,GALNT14,LRAT,ILDR2,GALNT3,GPR37,ICA1,EDA,RND3,PLOD2,ACER2,FMO4,SRD5A3,XBP1,OSBPL5,MYRF,CERS1,PTGES,B4GALT7,ABCG1 |
| 4.252e-05 | -10.07 | NUYTTEN_NIPP1_TARGETS_UP | MSigDB lists | NUYTTEN_NIPP1_TARGETS_UP | 698 | 101 | 17377 | 1707 |
EPHA3,PLA2G4A,CCDC126,NUDT10,ZSWIM5,FGF13,IL15,LSM11,PTPN21,ADAMTS6,SPATS2L,SNX9,DDX60L,BAG3,SPEG,SLC16A2,MARVELD2,PPFIBP1,GSTM3,PROS1,PCOLCE2,SP140,THSD1,ATP6AP1L,IL1RAP,SP140L,LAMP3,RWDD2A,PRAME,PDK1,EBPL,KLHL3,SPOCD1,TRAM1L1,GDPD1,NFIA,SATB2,ATF3,TMEM47,CA13,METAP1D,ISG20,AHRR,SH3RF1,P4HA2,NCOA7,DUSP19,P4HA1,GRB10,SERPINI1,FRMD5,TNIK,SEC24D,CYP2J2,FBXO4,BACE1,FZD8,MLF1,SLC25A27,SETBP1,HERC5,TJP1,ZNF215,CHSY1,SLC1A3,BEX2,MECOM,EFEMP1,FLRT3,GTF2F2,KCNMB3,SGK1,BNIP3,KIAA0408,SAMD13,VGLL4,DUSP1,PARP9,TMC7,VEGFC,ARAP2,PLEKHA8,NR4A1,FHL2,OGDHL,FERMT2,TGDS,SLC46A3,STEAP1,DPY19L2,PMEPA1,MPP7,PLOD2,MATN2,HK2,KIAA0513,PGM2L1,PLD1,GEM,DISP2,SLFN5 |
| 4.266e-05 | -10.06 | bZIP_2 | pfam domains | PF07716 | 12 | 7 | 17054 | 1666 |
CEBPB,CEBPA,DBP,HLF,CEBPD,DDIT3,XBP1 |
| 4.270e-05 | -10.06 | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | 325 | 55 | 17377 | 1707 |
CREB3L2,BCL11B,RUNX2,JDP2,PLAG1,OTX1,GATA3,CEBPA,STAT5B,ZNF219,NKX6-1,FOXP2,GRHL1,GATA2,MYC,SREBF1,TFAP2A,EBF4,POU2F2,GFI1,ETV1,SNAI2,CEBPD,RAX,MSX1,MEIS2,ATF4,KCNIP3,NR6A1,NR4A1,NKX3-2,NFIA,MEF2B,MAFB,ATF3,PRDM1,ATOH1,ZFPM2,BATF,ZIC1,BATF3,BCL11A,CEBPB,EBF1,NACC2,HEYL,KLF5,ZBTB20,HOXD13,DBP,NKX2-8,FOXA1,SIX2,DDIT3,MEF2C |
| 4.317e-05 | -10.05 | GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | 149 | 31 | 17377 | 1707 |
KLF8,TTC39B,CRIM1,RECK,HEBP1,COBLL1,PRKCQ,RAB38,FAM81A,NUDT12,NPDC1,PFN2,TNKS1BP1,WARS,DCBLD2,HEG1,CDS1,GYPC,PLAGL1,MFSD9,CHRNA5,GNB4,PCBP4,ALDH1L1,PCGF2,UACA,JAKMIP3,CMPK2,FMNL2,RASGRP1,MED12L |
| 4.339e-05 | -10.05 | CUB_dom | interpro domains | IPR000859 | 49 | 15 | 18492 | 1811 |
ADGRB3,ST14,BMP1,ATRNL1,C1R,PCOLCE2,SEZ6L2,NRP1,LRP3,ADGRG6,KREMEN1,LRP12,DCBLD1,DCBLD2,TLL2 |
| 4.372e-05 | -10.04 | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN | 184 | 36 | 17377 | 1707 |
MAN2B2,GPR65,MLF1,MCTP2,COBLL1,NRN1,CYP26A1,CPNE2,IDI1,CA2,PPFIBP1,STARD4,LRP6,PERP,GPR161,MED12L,DLGAP1,RAX,ABCC4,TUBA1A,NR4A1,MPP1,JPH1,PRICKLE1,VIM,CA13,BCL11A,SLC39A14,EBF1,GALNT3,AK1,KCNMB4,BACH2,GNB4,C1orf21,DISP1 |
| 4.372e-05 | -10.04 | GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN | MSigDB lists | GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN | 184 | 36 | 17377 | 1707 |
WASF3,RNF144A,XYLT1,GTF2IRD1,CEBPA,SPATS2L,LACC1,CA8,INPP1,ZSCAN5A,DDIT4,EPB41L3,BAG3,SIPA1L2,CHN2,SETDB2,CHRDL1,EEPD1,TBC1D8,CYP1B1,KCNH5,ATP11A,RAB38,ARRDC4,CLN5,HEG1,AHRR,PTPRJ,SH3RF1,PEMT,RGS10,ZNF704,BMPR1A,SPRY4,RAB30,STOM |
| 4.388e-05 | -10.03 | HORTON_SREBF_TARGETS | MSigDB lists | HORTON_SREBF_TARGETS | 24 | 10 | 17377 | 1707 |
CYP51A1,IDI1,HMGCS1,INSIG1,ALDOC,LDLR,STARD4,FASN,SQLE,DHCR7 |
| 4.392e-05 | -10.03 | HAN_SATB1_TARGETS_UP | MSigDB lists | HAN_SATB1_TARGETS_UP | 372 | 61 | 17377 | 1707 |
RUNX2,IL32,FN1,ZNF395,FGF13,STXBP6,ATP8A1,ITGA6,LMCD1,HBE1,PRKCA,FAM174B,DENND3,FOXG1,SATB1,MTUS1,MECOM,CDS1,EFEMP1,SLC22A18,PDE10A,TSC22D1,TSPAN13,LIMCH1,MYO6,SMAD6,PRR16,MAST4,CEBPD,HRASLS,DUSP1,CYP1B1,BDNF,HBG2,COL6A2,PXN,LRRC8B,MYO10,THSD4,AGPAT4,MPP1,SHANK2,AK4,TNS1,C4orf19,C1orf174,TPK1,GSN,ENPP1,PMEPA1,PTK7,PELI2,MATN2,INHBE,SQLE,TNFSF15,NRP1,CDH2,NR3C2,PKIA,RRAGD |
| 4.396e-05 | -10.03 | GO_CELLULAR_RESPONSE_TO_BMP_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_BMP_STIMULUS | 90 | 22 | 17377 | 1707 |
MSX1,ACVR1,ID1,RUNX2,FN1,SMAD9,BMPR2,LRP4,GATA3,RYR2,ACVR2B,KCND3,BMP6,SKI,TGFBR3,HEYL,CHRDL1,BMP1,ACVR2A,BMP4,BMPR1A,SMAD6 |
| 4.396e-05 | -10.03 | GO_RESPONSE_TO_BMP | MSigDB lists | GO_RESPONSE_TO_BMP | 90 | 22 | 17377 | 1707 |
MSX1,ACVR1,ID1,RUNX2,FN1,SMAD9,BMPR2,LRP4,GATA3,RYR2,ACVR2B,KCND3,BMP6,SKI,TGFBR3,HEYL,CHRDL1,BMP1,ACVR2A,BMP4,BMPR1A,SMAD6 |
| 4.413e-05 | -10.03 | LTE2_UP.V1_UP | MSigDB lists | LTE2_UP.V1_UP | 177 | 35 | 17377 | 1707 |
CREB3L2,UST,GALNT12,PSTPIP2,NOVA1,QPRT,HMGCS1,UNC13B,BACE2,KMO,EHD3,REEP1,OPN3,MARCKS,PROS1,CYP1B1,TBC1D8,FGFR4,RIN2,RHOQ,MEIS2,UROS,PNRC1,BNIP3L,FERMT2,PHACTR2,PDE8A,NPC2,ASPH,C4orf19,PLAGL1,P4HA2,CLMN,MAOA,RRAGD |
| 4.433e-05 | -10.02 | EGF_2 | prosite domains | PS01186 | 212 | 42 | 12060 | 1278 |
EPHA3,TENM1,BTC,CELSR1,CELSR3,LRP4,LDLR,LAMC3,SELL,GAS6,EPHB1,BCAN,DNER,HMCN1,EFEMP1,NELL2,VWDE,ITGB3,SCARF2,ATRNL1,LRP6,PROS1,SLIT2,ITGB7,TGFA,VLDLR,C1R,F12,HEG1,NRG3,FAT4,FBN1,ITGBL1,FAT1,CCBE1,THBS4,LAMB1,MATN2,BMP1,EGFL7,TMEFF2,TLL2 |
| 4.501e-05 | -10.01 | WTTGKCTG_UNKNOWN | MSigDB lists | WTTGKCTG_UNKNOWN | 484 | 75 | 17377 | 1707 |
PHACTR3,NEK10,ACVR1,FGF13,CADM2,SEZ6L2,NRXN1,DACH2,SP8,CYP26A1,ZNF362,EOMES,PPFIA2,STARD4,TMEM143,DAB2IP,PPP2R2B,MYT1,GATM,SP140L,DPP10,SESN2,DEPTOR,VIM,SLC25A28,KCND3,ATP1B1,BACH2,TDO2,ADRB1,DLX2,NRP1,TPM1,CRYL1,HEY1,JDP2,DHCR24,ZIC2,BTBD9,SFXN3,BMP6,NKX6-1,FOXP2,LRRN1,FRY,PDZD7,FRAS1,PDE10A,TSC22D1,NCAM1,MORN4,SEPT3,SMAD6,GFRA1,ZNF385A,RNF152,NOS3,DPYSL5,MN1,MID2,LRRIQ1,CACNA1E,ILDR2,HOXA1,HERPUD1,RERE,EBF1,GSTO2,OSBPL5,HK2,SEMA3A,FNBP1L,SFN,TLL2,PHC1 |
| 4.505e-05 | -10.01 | LRRIQ1 (leucine rich repeats and IQ motif containing 1) | protein interactions | 84125 | 28 | 11 | 17029 | 1718 |
EPHA3,FGFR4,ACVR1,LGR4,BMPR2,GTF2IRD1,ACVR2A,PTPRS,BMPR1A,ACVR2B,UNC5B |
| 4.512e-05 | -10.01 | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_UP | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_UP | 129 | 28 | 17377 | 1707 |
CXCR5,EXPH5,VEGFC,PDLIM7,TMEM63C,SCAMP1,TMEM65,FHDC1,TNFSF13B,RYR2,IL13RA1,CEBPA,NTRK3,FAM81A,PRKCA,FAM162A,HECTD2,SLC9A7,SCIN,GABARAPL1,PPFIBP1,OPN3,MYO3B,CNNM2,INPP5F,STON2,ATP1A3,HEY1 |
| 4.523e-05 | -10.00 | GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_NEURON_DIFFERENTIATION | 295 | 51 | 17377 | 1707 |
EPHA3,NBL1,FN1,ROBO2,BMPR2,PTPRD,AKAP5,APBB1,NTRK3,GDPD5,BMP6,PPP1R9A,NKX6-1,RND2,NUMBL,SCN1B,GATA2,BCL6,SGK1,DAB2IP,MARCKS,FIG4,PACSIN1,SLIT2,RIMS2,FES,BDNF,DISC1,RAPGEF2,VLDLR,FEZ1,AMIGO1,ATOH1,FGFR1,CPEB1,BAIAP2,MAP1B,BCL11A,NEGR1,GPRC5B,PTK7,HEYL,HGF,BMP4,NRP1,MAGI2,SHOX2,COBL,FOXA1,MEF2C,CNTN1 |
| 4.593e-05 | -9.99 | site of polarized growth | cellular component | GO:0030427 | 162 | 32 | 18223 | 1724 |
DBN1,GPM6A,FGF13,SHANK2,APBB1,EPS8,LRRK2,PREX1,KIF5C,FEZ1,NDRG2,SNAP25,KIF21B,PALLD,GDPD5,RAC3,PPP1R9A,TIAM2,SNCA,CCDC120,DOCK7,GPRIN1,FRY,MAP2,FLRT3,ADGRL1,TMOD2,CTTN,NRP1,NPTXR,COBL,SHTN1 |
| 4.599e-05 | -9.99 | SMID_BREAST_CANCER_NORMAL_LIKE_UP | MSigDB lists | SMID_BREAST_CANCER_NORMAL_LIKE_UP | 436 | 69 | 17377 | 1707 |
CXCR5,SORBS1,ID1,CFH,AASS,COL18A1,KCTD12,NRXN1,LCP2,COL14A1,DOCK2,SLCO3A1,TGFBR3,CPVL,CHRDL1,PROS1,SP140,MET,PLTP,CPE,LAMP3,CYP1B1,VNN2,ITGB7,SKAP2,ANK2,LRMP,RNF125,CR2,PRKCQ,COTL1,KCND3,CD40,ISG20,BCL11A,PRKCB,HGF,OXTR,NR3C2,LZTS1,PCSK5,MEF2C,BCL11B,CKAP2,ST6GAL1,LAMC3,SELL,CD7,SPINK5,SATB1,SEL1L3,IL18R1,EFEMP1,ABLIM1,ACTA2,PTPRCAP,SPRY2,FOXN3,C1R,LEPR,PTPRC,CD37,ID3,PELI2,MATN2,GEM,TNFRSF17,TESC,MME |
| 4.659e-05 | -9.97 | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | 72 | 19 | 17377 | 1707 |
BCL11B,PLA2G4A,CCDC126,GPR65,OBSCN,RNF125,ENAH,ATF3,AIG1,ADSSL1,TRPS1,ZNF827,ASNS,PLK2,LAPTM4B,PPARGC1A,TLN2,RAB30,RRAGD |
| 4.711e-05 | -9.96 | postsynaptic membrane | cellular component | GO:0045211 | 244 | 43 | 18223 | 1724 |
DNM3,CACNG3,GRIK2,GABRB2,APBB1,CLSTN2,GABRG2,PSD3,KCTD12,GABRR2,P2RY1,PRR7,CBLN1,NCS1,KCNJ4,SEMA4F,CHRNA5,GRIP1,LIN7A,CADPS2,MPDZ,CHRM3,DLGAP1,LZTS3,DISC1,ANK2,HOMER2,SHANK2,GRID1,CHRNA6,HIP1,NLGN4X,ARHGAP32,CPEB1,HOMER3,DAGLA,CAMK2N1,GRIK4,PTPRS,GRIN2D,DLG2,CDH2,LZTS1 |
| 4.789e-05 | -9.95 | protein localization to plasma membrane | biological process | GO:0072659 | 160 | 32 | 17256 | 1658 |
DPP10,TNIK,KCNIP3,FGF13,TSPAN15,ANK2,RAPGEF2,DCHS1,PKP2,GAS6,P2RY1,ATP1B1,SKAP1,ARHGAP44,EPB41L3,MYADM,FCHO2,CACNB2,EHD3,RAP2A,RAB26,RAB31,TNFRSF1A,ZDHHC23,MAP7,LRP6,PRKG2,PACSIN1,STXBP1,CDH2,TESC,KCNB2 |
| 4.810e-05 | -9.94 | V$OCT_Q6 | MSigDB lists | V$OCT_Q6 | 243 | 44 | 17377 | 1707 |
TCP11L2,ITPRIP,REL,CADM2,MGAT5B,NRXN1,FOXG1,HPCAL4,PPP2R3A,FSTL5,MTUS1,FOXP2,ZNF362,LRRN1,COL25A1,LHX6,RAB26,MPPED2,PRICKLE2,SLC6A15,TSPAN13,PPP2R2B,PDE4D,ETV1,DNAH5,SEMA6C,GAB2,BDNF,GPM6A,NR6A1,FZD4,STAT4,FGF12,NFIA,PRDM1,TCERG1L,EBF1,GPRC5B,MAP2K6,PAM,DLG2,TMOD2,MID1,TLL2 |
| 4.820e-05 | -9.94 | GO_REGULATION_OF_METAL_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_METAL_ION_TRANSPORT | 311 | 53 | 17377 | 1707 |
SCN5A,LGALS3,AKAP5,UBASH3B,LILRB1,NKAIN2,PKP2,CACNB4,NEDD4,NOS1AP,KCNAB1,KCNN2,AKAP7,SCN1B,CNKSR3,CACNB2,STC2,SGK3,TRPC1,SGK1,TSPAN13,PDE4D,HSPA2,PDGFRB,NOS3,DPP10,KCNIP3,ATF4,GSTM2,ANK2,PTPN6,JPH1,FGF12,PACSIN3,RYR2,GSTO1,ATP1B1,AMIGO1,SGK2,ASPH,SNCA,CXCL10,GNAO1,WFS1,KCNG1,BMP4,ATG5,TRPC3,TESC,CACNA2D1,ATP2B4,STOM,CNTN1 |
| 4.954e-05 | -9.91 | regulation of ion transport | biological process | GO:0043269 | 622 | 90 | 17256 | 1658 |
PRKN,CACNG3,ATP8A1,VAMP8,HECW2,LILRB1,PKP2,ABAT,CACNB4,NOS1AP,KCNAB1,KCNN2,TCAF2,KMO,CNKSR3,KCNS3,TRPC1,PDE4D,TMEM37,SCN2A,HSPA2,SCN3A,KCNB2,PDGFRB,ALG10B,DPP10,KCNIP3,ATF4,PTPN6,KCNH5,ANK2,SHANK2,JPH1,FGF12,CHRNA6,GSTO1,KCND3,ATP1B1,AMIGO1,FGFR1,SNCA,IRS2,CXCL10,WFS1,KCNG1,ATG5,PPARGC1A,CNTN1,MEF2C,KCNV1,SCN5A,LGALS3,UBASH3B,SCN8A,NKAIN2,P2RY1,KCNC4,NEDD4,KCNJ4,LRRC55,CA2,SCN1B,CACNB2,PRKCD,EHD3,STC2,PRELID1,PRKG2,TSPAN13,STXBP1,TNFRSF11A,SYK,NOS3,GSTM2,RAB3B,KCNQ3,CACNA1E,HOMER2,PACSIN3,RYR2,HOMER3,KCNK15,GNAO1,MAP2K6,GEM,TRPC3,TESC,CACNA2D1,ATP2B4,STOM |
| 4.971e-05 | -9.91 | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | MSigDB lists | BERENJENO_ROCK_SIGNALING_NOT_VIA_RHOA_DN | 44 | 14 | 17377 | 1707 |
PDLIM7,IGF1R,CSF1,XBP1,FASN,ACTA2,FERMT2,KLF5,WWC2,TPM1,NRP1,DOCK5,F3,LPP |
| 4.979e-05 | -9.91 | GO_CHANNEL_REGULATOR_ACTIVITY | MSigDB lists | GO_CHANNEL_REGULATOR_ACTIVITY | 123 | 27 | 17377 | 1707 |
DPP10,KCNV1,KCNIP3,CACNG3,FGF13,VAMP8,FGF12,PACSIN3,PKP2,AMIGO1,NRXN1,SGK2,HPCAL4,NEDD4,GPLD1,KCNMB4,KCNAB1,SCN1B,PRKCB,CACNB2,KCNMB3,KCNS3,PRKG1,SGK3,SGK1,TSPAN13,ATP2B4 |
| 4.984e-05 | -9.91 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | 178 | 35 | 17377 | 1707 |
DMXL2,GATA3,FAM102B,CHSY1,FAM13A,SATB1,ZFYVE9,EPDR1,CHN2,C1orf53,STARD4,TSPAN13,RAB27B,GFI1,PTPRE,CAND2,CTH,GAB2,ANTXR2,CD55,STAT4,SLC39A8,KIAA1324L,RNF125,SNTB1,MFSD6,HEG1,GNAI1,ENPP6,XBP1,KIAA0513,MAOA,SVIL,TPM1,RAB30 |
| 4.984e-05 | -9.91 | GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN | 178 | 35 | 17377 | 1707 |
PLSCR4,SEC24D,LDLR,GATA3,KIF5C,COBLL1,KCTD12,LRRC49,CHSY1,NEDD4,PPP2R3A,ASNS,PMAIP1,PPFIBP1,FAM107B,MYO6,GFI1,ANTXR2,ARAP2,CLYBL,NR4A1,STAT4,PTPN13,DNAJC6,HIP1,RNF125,ATF3,ST6GALNAC3,MFSD6,IRS2,ICA1,INSIG1,PLOD2,ERN1,SQLE |
| 5.018e-05 | -9.90 | GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP | MSigDB lists | GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP | 171 | 34 | 17377 | 1707 |
AMOTL1,FN1,OLAH,LMCD1,FAM102B,COL18A1,BCL6B,IKZF2,SLCO3A1,EPCAM,CHN2,DACT1,DSG2,SGK1,BEND4,TOX,MARCKS,IQGAP3,SLCO4C1,CPE,FADS1,GCNT2,KDM5B,FOXN3,TCEA3,ARHGAP32,ZDHHC14,ZNF711,AHRR,GNB4,C1orf21,FBRSL1,MLLT3,CRISPLD1 |
| 5.018e-05 | -9.90 | GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN | MSigDB lists | GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN | 171 | 34 | 17377 | 1707 |
TNIK,ANKRD13D,ID1,LGALS3,RNF144A,TBC1D1,ST6GAL1,SELL,PSD3,ADAMTS6,KIF21B,SNX9,SATB1,PGAP1,FRY,BCL6,SGK1,LRP12,CARD6,ITGB7,SH3BP2,CD55,TUBA1A,STAT4,RASA3,VIM,ATP1B1,ENPP1,ID3,MYADM,BACH2,RNF122,DENND5B,MEF2C |
| 5.018e-05 | -9.90 | GSE6259_BCELL_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_BCELL_VS_CD8_TCELL_DN | 171 | 34 | 17377 | 1707 |
LONRF1,C2orf88,AKAP5,YPEL2,FAM102B,FAM117B,LCP2,KIF21B,SATB1,IDI1,FBXO32,JAKMIP2,FAM84B,SLCO4C1,RAB27B,PTPRE,CEBPD,IGSF3,RHOQ,LRRC8B,FZD4,RAPGEF2,LRMP,ACVR2B,TAF4B,MBNL2,RNF44,RERE,BCL11A,DCBLD2,IRS2,ADAMTS3,GRB10,STON2 |
| 5.025e-05 | -9.90 | TIEN_INTESTINE_PROBIOTICS_24HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_DN | 214 | 40 | 17377 | 1707 |
ESRP1,MCTP2,CANX,SEL1L3,AARS,RPL13A,RPL34,DDIT4,ASNS,EEF2,RPS11,EIF1,PCK2,RPS23,LAMP3,GARS,CD55,SLC3A2,PNRC1,TES,BNIP3L,ATF3,PDE8A,FNDC3A,MBNL2,HERPUD1,WARS,CEBPB,SLC7A1,TMCO3,TRIB3,RPL12,INHBE,GRB10,KLF5,RPL4,SLC1A5,UNC5B,SLC43A1,TPT1 |
| 5.025e-05 | -9.90 | MODULE_129 | MSigDB lists | MODULE_129 | 214 | 40 | 17377 | 1707 |
WASF3,CELSR1,CFH,GRB14,PRSS12,ITGA6,SETBP1,RAC3,CTNNA2,GAS1,EFEMP1,ABLIM1,UNC13B,BCHE,NOVA2,SMTN,NAP1L3,GULP1,ARL4D,PTPRE,ZNF365,IL1RAP,NKX2-1,FZD1,DBN1,MYO10,MGST3,VLDLR,CBY1,PLCB1,LEPR,EML1,FGFR1,TRIM9,SMAD3,GPRC5B,P4HA2,SERPINI1,NRP1,PSPH |
| 5.089e-05 | -9.89 | GO_SYNAPTIC_MEMBRANE | MSigDB lists | GO_SYNAPTIC_MEMBRANE | 251 | 45 | 17377 | 1707 |
GRIK2,AKAP5,GABRB2,LRP4,APBB1,CLSTN2,GABRG2,PSD3,KCTD12,GABRR2,P2RY1,NRXN1,PRR7,CBLN1,NCS1,KCNJ4,SEMA4F,CHRNA5,FLRT3,GRIP1,LIN7A,CADPS2,MPDZ,CPE,RIMS2,ATP2B1,CHRM3,DLGAP1,DISC1,ANK2,HOMER2,SHANK2,GRID1,NLGN4X,CHRNA6,SNAP25,ARHGAP32,CPEB1,HOMER3,CAMK2N1,GRIK4,GRIN2D,DLG2,LZTS1,SNPH |
| 5.098e-05 | -9.88 | V$GATA1_05 | MSigDB lists | V$GATA1_05 | 266 | 47 | 17377 | 1707 |
TYRO3,ENO2,RBFOX2,CREB5,IKZF2,NEDD4,NEO1,MECOM,TRPS1,ARHGEF10L,FOXP2,SEC16B,SLC10A7,LHX6,SAMD11,HS3ST5,KCNS3,ETV1,CHRM3,NDUFA4L2,BDNF,MSX1,COL4A3,KLHL4,COL4A4,KCNH5,CYTH3,FERMT2,PLEKHA1,TMEM47,ZFPM2,CD40,SKAP1,ZIC1,CEBPB,SMAD3,ID3,KLF12,PLAGL1,EGFL7,KLF5,ZBTB20,TPM1,CDH2,FILIP1,FOXA1,HEY1 |
| 5.104e-05 | -9.88 | vesicle-mediated transport in synapse | biological process | GO:0099003 | 119 | 26 | 17256 | 1658 |
DOC2A,DNM3,SYT12,KIF5A,DNAJC6,OPHN1,NLGN4X,KIF5C,SNAP25,CANX,SYT14,PCLO,SNCA,TRIM9,SH3GL2,UNC13B,FCHO2,LIN7A,CADPS2,SEPT5,PACSIN1,STXBP1,TC2N,STON2,RIMS2,SNPH |
| 5.127e-05 | -9.88 | positive regulation of catalytic activity | biological process | GO:0043085 | 1413 | 179 | 17256 | 1658 |
ARHGAP26,ACSL1,FGF13,FAM13A,SNX9,STK24,NOS1AP,F3,ADPRHL1,SIPA1L2,PMAIP1,ITGB3,SERINC2,EPHB6,PCOLCE2,TLR4,TSHR,PRKACB,RASGRP1,PDGFRB,TBC1D8,COL4A3,ACVR1C,TGFA,LRRK2,ELMOD1,PRKAR2B,ACVR2B,ROR1,GSN,GPRC5B,NCKAP1L,ERN1,ADRB1,ARHGAP28,BBC3,DIRAS1,TPM1,NRP1,MAGI2,CACUL1,MEF2C,TYRO3,RGS16,ALOX5AP,FN1,STXBP5L,TBC1D1,ITGA6,SLK,OPHN1,DYNC1I1,PFN2,CHN1,IGF1R,MYC,PRELID1,SRGAP1,ADCY6,INAVA,NOS3,PAK1,FGFR4,TBC1D8B,VLDLR,EFNA3,RYR2,DUSP9,STRADB,HIP1,ARRDC4,PLCB1,FAM162A,TBC1D2,MMP15,MAPKAPK2,ADGRB3,CSF1,DOCK9,EPHA3,NEK10,AVPI1,RASAL2,DOCK1,GPR65,ARHGAP22,RGS20,NTRK3,LCP2,DDR1,PIBF1,TBC1D30,PPP1R9A,DOCK2,TIAM2,TBC1D19,TLR3,CDC14B,DAB2IP,MET,HSPA2,PERP,DOCK8,PFKFB2,FZD4,ADCY1,PREX1,PRKCQ,WNT11,ATP1B1,CD40,ASPH,TBC1D16,FGFR1,SNCA,SMAD3,RANBP2,ARHGAP21,NRG3,BEX3,ITGA2,MAP3K21,RGS10,DUSP19,TNFSF15,HGF,MAPK10,TENM1,TNIK,SERINC5,LPAR2,ARHGEF11,PAK5,FZD8,GAS6,PKN1,RGS7,EPHB1,TPD52L1,ARHGAP44,SYDE2,RGS17,CHN2,PRKCD,GHR,RALGAPA2,AFAP1L2,SH3PXD2B,ERRFI1,TBC1D9,IQGAP3,TNFRSF11A,SYK,SPRY2,RIN2,VAV3,ARAP2,RAPGEF2,ASAP3,RASA3,AGAP2,ARHGAP32,RACK1,TLR6,GPLD1,DKK1,PTPRC,TRIB3,FGR,DOCK7,TERT,ACER2,GNAO1,MAP2K6,BMP4,TBC1D4,MMP16,MAP3K20,ATP2B4 |
| 5.153e-05 | -9.87 | GO_ENDOPLASMIC_RETICULUM | MSigDB lists | GO_ENDOPLASMIC_RETICULUM | 1526 | 195 | 17377 | 1707 |
ACSL1,ATP8A1,DNAJC3,ASS1,ALG1L,ITPR2,PRKCA,ABHD4,NOS1AP,FKBP11,TXNDC5,CYP51A1,RTN1,FKBP9,KCNN2,SEC16B,NDUFB8,COL19A1,TMED9,RASGRP1,CYP1B1,ATL1,KCNIP3,ERGIC1,COL4A3,WLS,TGFA,LRRK2,JPH1,LRMP,NFE2L1,BNIP3L,MSRB3,KCND3,ZDHHC14,INSIG1,RASGRF2,P4HA2,ERN1,BBC3,PIK3C2B,TYRO3,SCN5A,ALOX5AP,SEC24D,CYP2J2,ST6GAL1,ELOVL7,DHCR24,CYP4V2,SCD,MLC1,SPINK5,PGAP1,GALNT1,RNF180,BNIP1,SEMA4F,SLC7A11,MSMO1,BCHE,BACE2,FLRT3,SREBF1,LRP6,GRIP1,BNIP3,LMAN2,NCEH1,FAR2,MOXD1,AGL,COL9A2,CKAP4,HMGCR,FGFR4,FADS1,DISC1,SLC37A1,RNF170,SLC27A2,SLC36A1,COL4A4,MGST3,GPSM1,EDEM3,CALCRL,RYR2,SHISA2,NPC2,CLN5,HERPUD1,MFSD2A,THBS4,TMEM117,SQLE,PTPRN2,PLD1,DHCR7,RNF122,OSBPL6,CREB3L2,PLA2G4A,ELOVL4,LPCAT2,XYLT1,COL18A1,SEZ6L2,LPIN3,CANX,NRXN1,COL14A1,CYP26A1,TXNRD3,CDS1,COL22A1,TLR3,COL25A1,ZDHHC6,REEP1,PROS1,SERPINH1,SNX10,ALG10B,ANTXR2,TMEM67,COL6A2,EBPL,TMEM43,LRRC8B,CYB5R2,C3orf52,TRAM1L1,ACO1,RAB38,ASPH,ATP10D,SNCA,GJC1,GABARAPL1,SLC39A14,WFS1,PEMT,P4HA1,RCN3,ALG11,CYP2U1,MBOAT2,NR3C2,HACE1,MYO1D,COL9A3,CLGN,BACE1,MCTP2,UBAC2,CLSTN2,COL4A5,RASD1,GAS6,NDFIP2,GDPD5,COL27A1,SOAT2,PRKCD,STC2,SGK1,CERS4,FIG4,RRAS2,ESD,FKBP14,ULBP1,PCSK6,CES3,TRPM4,GSTM2,AGPAT4,ELOVL3,ATP11A,ARHGAP32,LRAT,ILDR2,GPR37,PLOD2,FMO4,XBP1,OSBPL5,SRD5A3,CERS1,PTGES,CACNA2D1,ATP1A3,ABCG1,STOM |
| 5.170e-05 | -9.87 | chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | chromophobe_renal_cell_carcinoma | 432 | 68 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PDGFRB,PRKACB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,EPHB1,PKN1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,MAPKAPK2,TRIB3,FGR,PKN3,TERT,MAP2K6,AKT3,NEK11 |
| 5.170e-05 | -9.87 | kidney-carcinoma-chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-chromophobe_renal_cell_carcinoma | 432 | 68 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PDGFRB,PRKACB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,EPHB1,PKN1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,MAPKAPK2,TRIB3,FGR,PKN3,TERT,MAP2K6,AKT3,NEK11 |
| 5.176e-05 | -9.87 | GO_BASOLATERAL_PLASMA_MEMBRANE | MSigDB lists | GO_BASOLATERAL_PLASMA_MEMBRANE | 207 | 39 | 17377 | 1707 |
MYO1D,BMPR2,AKAP5,ST14,ITGA6,LDLR,TJP1,SLC1A3,P2RY1,SLC12A6,MLC1,DDR1,CTNNA2,EPCAM,KCNJ4,CA2,MARVELD2,MAP7,LIN7A,CNNM2,MET,SLCO4C1,CHRM3,ATP2B1,SLC40A1,ABCC4,ANK2,TGFA,ATP1B1,DSP,LEPR,ENPP1,ATP7B,CDH17,HPGD,DLG2,CDH2,SLC16A10,ATP2B4 |
| 5.210e-05 | -9.86 | FN3 | prosite domains | PS50853 | 193 | 39 | 12060 | 1278 |
EPHA3,TYRO3,ROBO2,FN1,PTPRD,IL13RA1,EPHB1,COL14A1,NEO1,FSD1,SPEG,LRRN1,CNTN4,IGF1R,ABI3BP,FLRT3,GHR,ANKFN1,EPHB6,NCAM1,FANK1,MID2,DCC,PTPRU,ATF7IP2,OBSCN,SDK1,FNDC3A,LEPR,PTPRC,TRIM9,PTPRJ,NCAM2,PTPRS,MYOM2,IL9R,MID1,LIFR,CNTN1 |
| 5.215e-05 | -9.86 | V$MYOD_Q6 | MSigDB lists | V$MYOD_Q6 | 229 | 42 | 17377 | 1707 |
CXCR5,PHACTR3,NBL1,CCDC148,RHOBTB1,ITGA6,SELL,TJP1,IKZF2,BEX2,CYP26A1,EPDR1,MTUS1,FBXO32,TECPR1,IKZF5,GATA2,TRIM3,FIG4,GFRA1,NEB,RIMS2,POU3F3,USP2,COL4A3,KCNH5,COL4A4,ANK2,WWC1,ATP1B1,FGF17,PLCB1,LRAT,HTR7,PTPRJ,RASGRF2,HEYL,B3GALT2,TUFT1,PPARGC1A,MID1,HS6ST3 |
| 5.220e-05 | -9.86 | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP | 130 | 28 | 17377 | 1707 |
MYO10,LRRC8B,ESRP1,ITGA6,C3orf52,EDEM3,PLS1,CTBP2,ATP1B1,PHLDA2,MECOM,CYP51A1,GALNT3,EPCAM,SFXN1,SLC39A14,DDAH1,CA2,PDZD8,SH3RF1,GPR160,MAP7,KLF5,SH3BGRL2,MYO6,SFN,PERP,CHMP4C |
| 5.264e-05 | -9.85 | GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | 312 | 53 | 17377 | 1707 |
CREB3L2,BCL11B,RUNX2,REL,PLAG1,OTX1,GATA3,STAT5B,CEBPA,OVOL2,TRPS1,GRHL1,GATA2,BHLHA15,MYC,EBF4,TFAP2A,SREBF1,POU2F2,ETV1,GLIS1,BARX1,CEBPD,RAX,MSX1,ATF4,MEIS2,NR6A1,NR4A1,ESRRG,NFIA,NFE2L1,MEF2B,MAFB,ATF3,ATOH1,BATF,ZIC1,CEBPB,EBF1,IKZF3,PLAGL1,HEYL,KLF5,HOXD13,PAX9,DBP,DLX2,NKX2-8,SIX2,DDIT3,FOXA1,MEF2C |
| 5.266e-05 | -9.85 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | 91 | 22 | 17377 | 1707 |
GNG12,DOCK1,SH2D2A,PACSIN3,NFE2L1,ENAH,KIF21B,PFN2,CD53,GABARAPL1,GJC1,PTPRC,NCKAP1L,PLK2,WWTR1,BMP1,TFAP2A,SGK1,SEMA3C,MPDZ,CKAP4,IGSF3 |
| 5.299e-05 | -9.85 | carboxylic acid biosynthetic process | biological process | GO:0046394 | 311 | 52 | 17256 | 1658 |
PLA2G4A,PRKAA2,UST,GPT2,SERINC5,ALOX5AP,ELOVL4,ENO2,AASS,OLAH,ELOVL7,UGDH,RIMKLA,ASS1,CBS,SCD,ABAT,SLC1A3,BCAN,PHGDH,ASNS,KMO,ALDOC,ENO1,GATM,SYK,CTH,FADS1,ATP5IF1,GAPDH,UROS,SLC27A2,PFKFB2,MGST3,ELOVL3,HACD1,FASN,OGDHL,PYCR1,RIMKLB,PLOD2,ALDOA,XBP1,HK2,HPGD,PGM2L1,DSEL,HK1,PTGES,OSBPL6,PSPH,ACSM3 |
| 5.321e-05 | -9.84 | chr2q32 | MSigDB lists | chr2q32 | 39 | 13 | 17377 | 1707 |
FAM171B,C2orf88,SLC40A1,MSTN,STAT4,DUSP19,HECW2,GULP1,DLX2,MFSD6,TMEFF2,INPP1,OSBPL6 |
| 5.410e-05 | -9.82 | V$POU6F1_01 | MSigDB lists | V$POU6F1_01 | 222 | 41 | 17377 | 1707 |
PCDH18,INPPL1,FGF13,CHCHD7,RHOBTB1,RBFOX2,PLAG1,TNFSF13B,BEGAIN,GTF2IRD1,CREB5,IKZF2,CBLN1,PCDH7,FOXP2,EFEMP1,ZNF827,ABLIM1,FBXO32,KCTD15,COL25A1,MPPED2,PRICKLE2,MARCKS,NCAM1,MYT1,TSPAN9,ETV1,DUSP1,MEIS2,NR6A1,FOXN3,PRDM13,ZFPM2,RERE,NSD1,GRIK4,ERN1,DLG2,ZBTB20,PPARGC1A |
| 5.424e-05 | -9.82 | protein domain specific binding | molecular function | GO:0019904 | 648 | 94 | 17224 | 1680 |
PRKN,TRIM16,DOCK1,GRIK2,AKAP5,LILRB1,GATA3,ENAH,DOCK3,TNKS1BP1,PPP1R9A,ZFYVE9,TRPS1,SKI,TGFBR3,KCNN2,KCNAB1,IKZF5,ZNF521,ACVR2A,LIN7A,DAB2IP,POU2F2,SYNGR3,RAB27B,HSPA2,POU3F3,FZD1,TNK2,EVL,ATF4,GAPDH,TUBA1A,FZD4,PTPN6,SHANK2,DNAJC6,NFE2L1,TCEAL3,VIM,PRKAR2B,PLEKHA1,CD40,WARS,TRIM9,WIPF3,ADRB1,MEF2C,MYO1D,GNG12,SCN5A,INPPL1,PLSCR4,RUNX2,FN1,MLF1,FZD8,GPSM2,NDFIP2,NEDD4,KCNJ4,GATA2,AFAP1L2,SH3PXD2B,ERRFI1,STXBP1,SYK,ATP2B1,EPB41L5,DLGAP1,RHOQ,SH3BP2,SH2D2A,CRIM1,ESRRG,RAPGEF2,HOMER2,LITAF,RACK1,SKAP1,KHDRBS2,BAIAP2,HOMER3,ID3,ICA1,MPP7,PMEPA1,HEYL,SH3BGRL2,FOXA1,DDIT3,ATP2B4,OCLN,SFN |
| 5.436e-05 | -9.82 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | 193 | 37 | 17377 | 1707 |
SERINC5,ACSL1,FLVCR2,CEBPA,CTBP2,FAM198B,CREB5,SLCO3A1,ARHGEF10L,RTN1,LIN7A,SGK1,ENO1,CEBPD,TBC1D8,FZD1,MICAL2,PXN,ALDH2,SLC36A1,MPP1,MAFB,SMARCD3,PHACTR2,VIM,ATF3,DOCK5,GABARAPL1,HPSE,NACC2,ALDOA,EMILIN2,RGS10,KIAA0513,RNF130,PCSK5,RRAGD |
| 5.436e-05 | -9.82 | GSE7460_TCONV_VS_TREG_THYMUS_DN | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_DN | 193 | 37 | 17377 | 1707 |
MYO1D,RGS16,LGALS3,CHCHD7,CYP4V2,KIF5C,IKZF2,IL18R1,GPR15,EOMES,STARD4,KIAA0319,MYO3B,TSPAN13,KLF9,MED7,SNX10,IGSF3,CHSY3,PNP,CRIM1,WLS,GSTO1,PRDM1,CD40,TTC28,PEAK1,FAM162A,GABARAPL1,CEBPB,IKZF3,MYADM,PLAGL1,PTPRS,SH3BGRL2,NRP1,CSRP2 |
| 5.464e-05 | -9.81 | LYZL2 (lysozyme like 2) | protein interactions | 119180 | 54 | 16 | 17029 | 1718 |
TMEM67,MRC2,COL6A2,CNTNAP3,GAS6,ASPH,COL14A1,CHST10,IGF1R,ERO1B,C1QL4,LAMB1,VWDE,PROS1,GALNT18,FKBP14 |
| 5.470e-05 | -9.81 | GO_STEROL_METABOLIC_PROCESS | MSigDB lists | GO_STEROL_METABOLIC_PROCESS | 117 | 26 | 17377 | 1707 |
PRKAA2,MVK,EBPL,MVD,CYB5R2,VLDLR,LDLR,DHCR24,CYP4V2,CEBPA,NPC2,LEPR,CYP51A1,IDI1,HMGCS1,INSIG1,SOAT2,MSMO1,OSBPL5,SREBF1,SQLE,TNFSF4,DHCR7,ABCG1,CYP1B1,HMGCR |
| 5.495e-05 | -9.81 | distal axon | cellular component | GO:0150034 | 261 | 45 | 18223 | 1724 |
FGF13,GRIK2,PRSS12,APBB1,EPS8,BLVRB,OPHN1,KIF5C,NDRG2,KIF21B,KCNC4,GDPD5,PFN2,RAC3,PPP1R9A,TIAM2,CCDC120,GPRIN1,UNC13B,FLRT3,ADGRL1,CTTN,PACSIN1,NPTXR,CHRM3,DBN1,GPM6A,KCNIP3,SHANK2,LRRK2,PREX1,FEZ1,ROR1,SNAP25,PALLD,SNCA,DOCK7,MAP2,ITGA2,RGS10,PTPRN2,TMOD2,NRP1,COBL,SHTN1 |
| 5.515e-05 | -9.81 | substrate-dependent cell migration | biological process | GO:0006929 | 25 | 10 | 17256 | 1658 |
EPB41L5,VEGFC,PTPRC,ITGA2,OPHN1,CTTN,NRP1,SEMA3A,SLIT2,SHTN1 |
| 5.521e-05 | -9.80 | GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 367 | 60 | 17377 | 1707 |
RPS20,TNIK,FGF13,TSPAN15,GRIK2,LRP4,PKP2,P2RY1,GAS6,NRXN1,TSPAN17,RPL13A,RPL34,EPB41L3,PMAIP1,RPS11,CACNB2,EHD3,REEP1,RAP2A,RAB26,ZDHHC23,MAP7,PRKG2,LIN7A,LRP6,SH3PXD2B,PACSIN1,RPL26L1,STXBP1,CPE,RPS23,KCNB2,RPS13,DPP10,ITGB7,RPL26,KCNIP3,RAPGEF2,ANK2,TRAM1L1,RPL21,FERMT2,RAB38,ATP1B1,SKAP1,RPL12,MYADM,RPL28,FCHO2,WDR19,TNFRSF1A,RAB31,BBC3,DLG2,RPL4,RPS12,CDH2,MAGI2,TESC |
| 5.539e-05 | -9.80 | GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_UP | 186 | 36 | 17377 | 1707 |
RGS16,FARP1,ACSL1,DYRK3,ENO2,BMPR2,CELSR3,SCN8A,ST6GAL1,SELL,SEL1L3,SPINK5,MET,GFI1,IL1RAP,COL9A2,IGSF3,FER,SLC3A2,COL4A3,SH2D2A,SLC39A8,MPP1,ABCC2,ATF3,CBY1,FNDC3A,GNAI1,ENPP1,INSIG1,SLC7A5,LAPTM4B,GRB10,PKIA,ATP2B4,RRAGD |
| 5.539e-05 | -9.80 | GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP | 186 | 36 | 17377 | 1707 |
TYRO3,GXYLT2,GALNT6,GTF2IRD1,SLC1A3,SEZ6L2,CHD5,BAG3,UNC13B,FAM168A,ALDH1L1,MARCH3,PRICKLE2,CADPS2,CTTN,NCEH1,SYNGR3,CHRM3,ZNF629,TMC7,FADS1,SH3BP2,MYO10,BTNL9,SDC3,TTC28,FAM162A,CEBPB,ENPP1,VPS37D,KIAA0513,TMEM117,PLD1,MBOAT2,KIF1B,ABCG1 |
| 5.539e-05 | -9.80 | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | MSigDB lists | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | 186 | 36 | 17377 | 1707 |
MOCOS,PRSS16,BACE1,TNFAIP8L2,TNFSF13B,SELL,CEBPA,PHGDH,SATB1,MTUS1,TRPS1,SIPA1L2,ABLIM1,COL22A1,PIK3AP1,KMO,ALDOC,SRGAP1,ATRNL1,POU2F2,POU3F3,FGFR4,KCNQ3,ARID5B,DUSP9,SHISA2,PYCR1,ZIC1,GALNT3,HPSE,GPR160,ENTPD7,LAPTM4B,NRP1,DIRC2,CTNND2 |
| 5.546e-05 | -9.80 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_UP | 144 | 30 | 17377 | 1707 |
TNIK,USP2,GSTM2,PNRC1,CRIM1,EXOC6B,OPHN1,IGF2BP2,NOVA1,ZFYVE9,SYDE2,MECOM,GALNT3,FBXO32,IGF1R,SCN1B,TACC2,GPR160,INPP4B,AHNAK2,TMEM117,HPGD,TUFT1,LRP6,SVIL,DSEL,HGF,CTTN,SERPINH1,NRP1 |
| 5.555e-05 | -9.80 | V$IRF1_Q6 | MSigDB lists | V$IRF1_Q6 | 237 | 43 | 17377 | 1707 |
SORBS1,GPR65,VAMP8,EPS8,TNFSF13B,OTX1,TNFRSF19,FOXG1,IKZF2,NEDD4,CD53,SGK1,PRICKLE2,FIGN,GFI1,VGLL4,ZNF385A,ATP2B1,FES,NKX2-1,DPP10,ITGB7,MSX1,ESRRG,FGF12,PLS1,IRS2,EBF1,CD37,NCAM2,ENPP6,PRKCB,B3GALT2,P4HA1,ZBTB20,DLG2,HOXD13,HGF,SERPINI1,PPARGC1A,NR3C2,CTNND2,MEF2C |
| 5.612e-05 | -9.79 | DOUGLAS_BMI1_TARGETS_UP | MSigDB lists | DOUGLAS_BMI1_TARGETS_UP | 528 | 80 | 17377 | 1707 |
NMNAT3,PDE1B,SCAMP1,RASAL2,FGF13,AASS,KCTD12,DNER,ZFYVE9,TUBB4A,RND2,NELL2,KCTD15,PMAIP1,KMO,RAB26,STEAP3,DAB2IP,PLTP,FZD1,COL6A2,EIF4E3,RNF145,PRKAR2B,ATP1B1,DSP,TBC1D16,NT5DC2,CENPV,DCBLD2,IRS2,SLC39A14,GSN,GPRC5B,TDO2,RBPMS2,INPP4B,TPM1,SEPT5,INPPL1,FARP1,FN1,TNFSF13B,ZIC2,SCD,PRDM8,SLC1A3,NEO1,FSD1,MGAT1,PCBP4,SREBF1,TRIM3,KIAA0408,FAM84B,SMAD6,BARX1,GFRA1,PCSK6,FGFR4,PNP,NR4A1,MPP1,DCHS1,FASN,HIP1,OBSCN,B4GALNT3,GALNT14,TEX15,CACHD1,MFSD2A,SRD5A3,HK2,NXPH4,CERS1,RNF122,PANK3,DOCK6,PKIA |
| 5.659e-05 | -9.78 | transmembrane receptor protein tyrosine kinase signaling pathway | biological process | GO:0007169 | 523 | 78 | 17256 | 1658 |
EPHA3,BTC,SORBS1,DOCK1,RBFOX2,NTRK3,STAT5B,LCP2,PRKCA,DDR1,ITGB3,DAB2IP,EPHB6,MET,PDGFRB,GAB2,TNK2,FER,COL4A3,TGFA,FGF12,FGF17,PLEKHA1,ROR1,FRK,FGFR1,IRS2,NRG3,PTPRJ,NCKAP1L,EIF4EBP1,MAPK13,HGF,GRB10,NRP1,EFNB2,BMPR2,ESRP1,UBASH3B,EPS8,ATP6V1E2,COL4A5,EPHB1,CD7,DOK5,DDIT4,EFEMP1,CHN1,IGF1R,FLRT3,GHR,GTF2F2,SREBF1,GFRA1,SYK,FES,FGFR4,PAK1,VEGFC,BDNF,VAV3,RHOQ,ARHGEF28,PXN,CRIM1,SH2D2A,RAPGEF2,ARID5B,EFNA3,GAREM1,PLCB1,BAIAP2,GPLD1,GALNT3,MAPKAPK2,FGR,FAT4,CSF1 |
| 5.675e-05 | -9.78 | GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_UP | MSigDB lists | GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_UP | 172 | 34 | 17377 | 1707 |
RUNX2,TTC39B,SCAMP1,ATP9A,UBASH3B,NPM1,ADAMTS6,NRN1,HOPX,EPCAM,VWA5A,CPE,NEB,MID2,TDRD3,PLEKHA8,SH2D2A,PTPN13,ST6GALNAC3,PRDM1,ENTPD1,SFXN1,CD37,TMEM154,PLAGL1,KLF12,SH3RF1,CSF1,MATN2,PCGF2,NRP1,TBC1D4,IL9R,NR3C2 |
| 5.675e-05 | -9.78 | V$FOXJ2_01 | MSigDB lists | V$FOXJ2_01 | 172 | 34 | 17377 | 1707 |
TYRO3,BCL11B,ID1,RUNX2,SCAMP1,CHCHD7,PLAG1,CREB5,LCP2,DOCK3,NOVA1,TSPAN17,HMCN1,NEO1,TRPS1,FOXP2,ATXN7L1,CHN2,KCTD15,SLC10A7,NCAM1,ERRFI1,GFI1,GFRA1,SSH3,MSTN,SLC39A8,ESRRG,PRDM1,KLF12,GNAO1,ZBTB20,PKIA,MEF2C |
| 5.725e-05 | -9.77 | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | MSigDB lists | HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_UP | 73 | 19 | 17377 | 1707 |
CFH,PTPRD,DNAJC6,GATA3,MECOM,BAG3,ID3,HLF,CHN2,CDC14B,PLOD2,CACNB2,INPP4B,LAPTM4B,MPDZ,SERPINI1,KLF9,TPM1,MLLT3 |
| 5.742e-05 | -9.77 | regulation of actomyosin structure organization | biological process | GO:0110020 | 87 | 21 | 17256 | 1658 |
PAK1,PHLDB2,EVL,PXN,MYLK3,GPR65,ASAP3,SORBS3,WNT11,PFN2,PPP1R9A,ARHGEF10L,SMAD3,PPM1E,ARHGAP28,SH3PXD2B,TPM1,NRP1,MET,TMEFF2,MEF2C |
| 5.742e-05 | -9.77 | regulation of synapse assembly | biological process | GO:0051963 | 87 | 21 | 17256 | 1658 |
BDNF,SLITRK2,ROBO2,PTPRD,CLSTN2,SLITRK5,NTRK3,AMIGO1,EPHB1,NRXN1,PPP1R9A,CBLN1,ADGRB2,SNCA,LRRN1,ADGRB3,FLRT3,ADGRL1,OXTR,IL1RAP,MEF2C |
| 5.748e-05 | -9.76 | GO_PROTEIN_HOMODIMERIZATION_ACTIVITY | MSigDB lists | GO_PROTEIN_HOMODIMERIZATION_ACTIVITY | 678 | 98 | 17377 | 1707 |
NBL1,ACVR1,ID1,GRIK2,LILRB1,ADD2,NPM1,CTBP2,CEBPA,CHUK,CADM2,MAPK4,ABAT,RBM11,SNX9,IKZF2,CBLN1,PPP1R9A,SLC9A7,QPRT,ASNS,KCNN2,AADAT,GSTM3,DAB2IP,PTPRE,ZNF365,SLIT2,RASGRP1,GCA,NR6A1,FZD4,MVD,LRRK2,BNIP3L,NLGN4X,CR2,ATF3,JAM3,FGFR1,PLEKHB1,BCL11A,SMAD3,TRIM9,ENPP1,IKZF3,ERN1,WWTR1,HPGD,ERCC5,INPP5F,BMPR1A,MID1,PSPH,CHMP4C,CRYL1,CARS,ZHX3,FBXO4,SLK,LRP4,CBS,ADSSL1,TPD52L1,GRPEL2,MECOM,FOXP2,PRTFDC1,ZBTB38,HMGCS1,PDZD7,BHLHA15,FLRT3,GHR,STC2,TFAP2A,LRP6,PRKG2,BNIP3,HMGCR,MID2,GSTM2,GSTM4,HOMER2,FASN,LHPP,PLCB1,CEBPB,NACC2,TERT,CSF1,HEYL,XBP1,BMP4,TESC,DDIT3,ABCG1,STOM |
| 5.778e-05 | -9.76 | organic acid biosynthetic process | biological process | GO:0016053 | 312 | 52 | 17256 | 1658 |
PLA2G4A,PRKAA2,UST,GPT2,SERINC5,ALOX5AP,ELOVL4,ENO2,AASS,OLAH,ELOVL7,UGDH,RIMKLA,ASS1,CBS,SCD,ABAT,SLC1A3,BCAN,PHGDH,ASNS,KMO,ALDOC,ENO1,GATM,SYK,CTH,FADS1,ATP5IF1,GAPDH,UROS,SLC27A2,PFKFB2,MGST3,ELOVL3,HACD1,FASN,OGDHL,PYCR1,RIMKLB,PLOD2,ALDOA,XBP1,HK2,HPGD,PGM2L1,DSEL,HK1,PTGES,OSBPL6,PSPH,ACSM3 |
| 5.779e-05 | -9.76 | ZHU_CMV_ALL_DN | MSigDB lists | ZHU_CMV_ALL_DN | 124 | 27 | 17377 | 1707 |
MN1,COL6A2,PTPN13,LDLR,ACO1,C1R,AARS,GAS1,DDIT4,PYCR1,EFEMP1,CHN1,TGFBR3,IGF1R,CFHR1,TNFRSF1A,TFAP2A,ZNF521,ACTA2,ACVR2A,ERCC5,MARCKS,BMP4,TPM1,CEBPD,CYP1B1,IGFBP3 |
| 5.786e-05 | -9.76 | V$P53_02 | MSigDB lists | V$P53_02 | 230 | 42 | 17377 | 1707 |
BCL11B,MRC2,BMPR2,RHOBTB1,FHDC1,OTX1,PRDM8,CHUK,NTRK3,GABRR2,SLC1A3,SLC12A6,DDR1,FOXG1,SP8,ARHGAP44,ZNF362,DNAH6,CACNB2,TSC22D1,DAB2IP,SCN2A,ETV1,TMC7,VAV3,MEIS2,GCNT2,CACNA1E,ESRRG,ARRDC4,MBNL2,PLCB1,BCL11A,DYRK1B,NXPH4,DSEL,LRRK1,DDIT3,FILIP1,CTNND2,LPP,HS6ST3 |
| 5.949e-05 | -9.73 | positive regulation of cellular metabolic process | biological process | GO:0031325 | 3074 | 354 | 17256 | 1658 |
THOC5,ACVR1,LGR4,DNAJC3,LDLR,GATA3,NPM1,CTBP2,STAT5B,CEBPA,PRKCA,SNX9,EYA4,STK24,NOS1AP,TRPS1,SKI,PMAIP1,FAM168A,RAP2A,TSHR,POU3F3,NKX2-1,MEIS2,SMAD9,ACVR1C,NR6A1,TGFA,LRRK2,NFIA,BNIP3L,MEF2B,PRKAR2B,ACVR2B,F12,AHRR,HLF,NCKAP1L,CCBE1,PLK2,ADRB1,BBC3,DIRAS1,INPP5F,NRP1,MEF2C,ITGA6,SLK,TNFRSF10C,TNFRSF19,MECOM,APLF,MYC,PRELID1,SREBF1,GRIP1,GLIS1,PRR16,GPR161,RNF152,HMGCR,RPL26,STAT4,VLDLR,FHL2,FASN,PACSIN3,NSD2,HIP1,SMARCD3,TAF4B,ARRDC4,PLCB1,FAM162A,PELI2,THBS4,INHBE,HOXD13,CDH2,SMYD3,EPHA3,ZNF516,RNF144A,OTX1,CHUK,LCP2,DDR1,TLR3,DACT1,STARD4,DAB2IP,PERP,FZD1,FZD4,PFKFB2,SOX21,ADCY1,ATF3,SATB2,PRKCQ,WNT11,PXYLP1,PYGO1,ATOH1,ASPH,FGFR1,SNCA,IRS2,ZNF711,CXCL10,IKZF3,BEX3,WFS1,APELA,PEMT,WWTR1,MAP3K21,TNFSF15,KLF5,BMPR1A,DBP,MAPK10,HOXB9,MID1,EDA2R,CKAP2,PLAG1,CD276,FZD8,GAS6,P2RY1,CREB5,PKN1,EPHB1,ZNF219,NDFIP2,TPD52L1,GSAP,KDM7A,BHLHA15,GHR,YBX3,MYO6,SMAD6,SPRY2,ZFP36L2,MED12L,PARP9,PFKFB4,VEGFC,SLC40A1,VAV3,RAPGEF2,GAREM1,RACK1,GUCY1A2,SKAP1,HOXA1,ZIC1,GPLD1,CEBPB,PTPRC,TRIB3,NSD1,FGR,TERT,XBP1,BMP4,LRRK1,SHOX2,DDIT3,ATP2B4,FOXA1,LARP1,BTRC,ACSL1,FGF13,TRIM16,ASS1,LILRB1,ABAT,IKZF2,GSDME,F3,ARHGEF10L,EPCAM,EOMES,GRHL1,ITGB3,PCOLCE2,EPHB6,ENO1,FANK1,TLR4,ETV1,PDGFRB,RASGRP1,PRKACB,TNK2,ATF4,GCNT2,SESN2,COL4A3,NFE2L1,YAP1,ROR1,BATF,SESN1,DYRK1B,INHBC,GSN,GPRC5B,INSIG1,ERN1,NCOA7,TNFRSF1A,DLX2,PPARGC1A,TNFSF4,MAGI2,CACUL1,MLLT3,BCL11B,PRKAA2,TYRO3,LONRF1,RUNX2,FN1,BVES,JDP2,FBXO4,SORBS3,ZIC2,PFN2,RNF180,ZBTB38,EEF2,IGF1R,GATA2,EBF4,LRP6,ADCY6,INAVA,BNIP3,BARX1,CAND2,CEBPD,NOS3,PAK1,FGFR4,RAX,ATP5IF1,MID2,RHOQ,MSTN,GPSM1,EFNA3,WWC1,STRADB,MAFB,DUSP9,PDE8A,HERPUD1,MAPKAPK2,PLAGL1,HEYL,CSF1,SH3BP4,HK2,NKX2-8,SEMA3A,TESC,SIX2,CREB3L2,PRKN,SORBS1,NEK10,AVPI1,IL15,NTRK3,LPIN3,TNKS1BP1,PIBF1,PPP1R9A,CDC14B,BCL6,ACVR2A,POU2F2,MET,HSPA2,GLI1,IGFBP3,ALG10B,NOP53,RNF125,VIM,RARRES2,CD40,SMAD3,NRG3,RNF217,ITGA2,DUSP19,SOHLH2,HGF,HEY1,CNTN1,TENM1,TNIK,NECAB2,BMPR2,ARHGEF11,PAK5,REL,APBB1,LRP4,SLX1B,OVOL2,BMP6,NKX6-1,PRKCD,RASD2,GTF2F2,TFAP2A,AFAP1L2,IQGAP3,TNFRSF11A,SYK,SLC45A3,MOB1B,MICAL2,MSX1,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,PRICKLE1,MARS,AGAP2,ZFPM2,TLR6,MGMT,DKK1,RERE,EBF1,GPR37,DDAH1,DOCK7,ACER2,MAP2K6,MYRF,PAX9,MAP3K20 |
| 5.966e-05 | -9.73 | regulation of anatomical structure morphogenesis | biological process | GO:0022603 | 1135 | 148 | 17256 | 1658 |
ACVR1,FGF13,LGR4,GATA3,PRKCA,RAC3,F3,RND2,RAP2A,CTTN,SLIT2,CYP1B1,COL4A3,CEMIP2,DCC,LRRK2,AGO4,ROR1,GPC6,WIPF3,MAP2,CCBE1,PLK2,ALDOA,SEMA3C,TPM1,NRP1,PPARGC1A,VASH2,SPART,MAGI2,MLLT3,MEF2C,UST,RUNX2,FN1,CELSR1,RHOBTB1,PTPRD,BVES,SPINK5,CHN1,KIAA1958,SEMA4F,GATA2,MYC,GRIP1,BNIP3,TSPAN12,FMNL2,RIMS2,NOS3,PAK1,ENAM,BDNF,RHOQ,MYO10,EFNA3,BAIAP2,RIPOR2,ADGRB3,THBS4,CSF1,HK2,HOXD13,CDH2,SEMA3A,SIX2,SHTN1,PRKN,DNM3,ZSWIM5,ID1,RHOD,DOCK1,CELSR3,PLXNA2,HECW2,NTRK3,SEMA6A,PPP1R9A,CD53,EPB41L3,TLR3,PDZD8,DACT1,BCL6,DAB2IP,FZD1,GLI1,SSH3,PHLDB2,MYLK3,FZD4,ADM2,PREX1,WNT11,SYNJ2BP,AMIGO1,CD40,DOCK5,FGFR1,WARS,CXCL10,PRKCB,APELA,PTK7,GBP1,PTPRS,HGF,BMPR1A,HEY1,WASF3,TNIK,ROBO2,BMPR2,LRP4,EPS8,TNFSF13B,PKN1,ARHGAP44,ADGRB2,NEDD4,NKX6-1,FOXP2,TFAP2A,PRICKLE2,SPRY2,FES,VEGFC,LZTS3,MSX1,RAPGEF2,PRICKLE1,FERMT2,RACK1,DKK1,MAP1B,DDAH1,FGR,MYADM,RND3,TERT,AKT3,XBP1,PAX9,BMP4,SHOX2 |
| 5.985e-05 | -9.72 | phosphate-containing compound metabolic process | biological process | GO:0006796 | 2050 | 247 | 17256 | 1658 |
NMNAT3,MVK,ADAL,ACVR1,PDE1B,FGF13,DUSP8,PTPN21,STAT5B,PRKCA,ABHD6,ABHD4,EYA4,STK24,QPRT,MOK,PPM1E,RPS6KA2,TGFBR3,PALD1,SERINC2,NDUFB8,PPP2R2B,EPHB6,PTPRE,TLR4,ENO1,PRKACB,RASGRP1,PDGFRB,NKX2-1,TNK2,MARK1,SMAD9,ACVR1C,LRRK2,DNAJC6,GDPD1,PLPP2,ACVR2B,ROR1,FGF17,PLEKHA1,SGK2,GRK3,NT5DC2,DYRK1B,AK1,ENPP1,ENPP6,RASGRF2,PLK2,ERN1,ALDOA,MAPK13,INPP5F,PIK3C2B,OXTR,MEF2C,CRYL1,PRKAA2,TYRO3,MOCOS,LATS2,INPPL1,PTPRD,SLK,UBASH3B,ISYNA1,ADSSL1,TNFRSF19,PGAP1,DOK5,EFEMP1,PRTFDC1,IGF1R,ADCK1,PIK3AP1,MYC,PDE10A,PRKG1,ADCY6,ALPK1,NCAM1,MAST4,GFRA1,HMGCR,PAK1,FADS1,FGFR4,IL17RD,PODXL2,RHOQ,PNP,PLEKHA8,DUSP9,STRADB,OBSCN,PDE8A,CDC42BPA,LHPP,PLCB1,MAPKAPK2,PKN3,PELI2,MFSD2A,MPP2,HK2,PTPRN2,PLD1,PANK3,AMPD1,PLA2G4A,EPHA3,BTC,NUDT10,NEK10,RASAL2,IL15,LPCAT2,CHUK,MAPK4,NTRK3,GRK6,LPIN3,PIBF1,NUDT12,DDR1,CDS1,SPEG,PLPP1,IDI1,TLR3,KMO,CDC14B,RPS6KL1,ALDOC,MYO3B,ACVR2A,DAB2IP,FHIT,PDE4D,MDH1B,MET,IGFBP3,FER,SSH3,MYLK3,GAPDH,GARS,PDK1,ADM2,PFKFB2,PTPRU,PTPN6,MVD,KCNH5,PANK1,ADCY1,PRKCQ,WNT11,PXYLP1,ATP1B1,FRK,ETNPPL,MAGI3,FGFR1,SNCA,TPK1,IRS2,PTPRJ,PRKCB,PEMT,PTK7,ABI3,INPP4B,MAP3K21,DUSP19,PTPRS,HGF,BMPR1A,MAPK10,MBOAT2,PSPH,MAST1,SERINC5,TNIK,DYRK3,BMPR2,ENO2,PAK5,GAS6,PKN1,EPHB1,INPP1,PPP2R3A,HMGCS1,PRKCD,GHR,SGK3,SGK1,PRKG2,FIG4,PCK2,IQGAP3,SYK,ZFP36L2,SMPDL3A,FES,PARP9,DUSP1,PFKFB4,PPP1R3D,HYKK,PTPN13,MPP1,AGPAT4,RAPGEF2,NUAK2,OGDHL,RASA3,AK4,CTTNBP2NL,GUCY1A2,PEAK1,SMPDL3B,GPLD1,PTPRC,TRIB3,FGR,PLPPR2,MAP2K6,AKT3,OSBPL5,SRD5A3,PGM2L1,NEK11,GRIN2D,PIP5KL1,DLG2,HK1,BMP4,LRRK1,CMPK2,MAP3K20,BTRC,NUDT17 |
| 5.985e-05 | -9.72 | regulation of molecular function | biological process | GO:0065009 | 3181 | 365 | 17256 | 1658 |
ARHGAP26,PPP4R4,DUSP8,RECK,DNAJC3,GATA3,NPM1,CEBPA,SNX9,STK24,NOS1AP,SKI,BAG3,TYMP,PPP1R26,TGFBR3,PMAIP1,ZFYVE28,CFHR1,SERINC2,PPP2R2B,RCAN3,TSHR,TBC1D8,ACVR1C,WISP3,CAP2,TGFA,LRRK2,ELMOD1,DEPTOR,PRKAR2B,ACVR2B,FGF17,SAV1,SH3RF1,NCKAP1L,PLK2,ADRB1,BMP1,ARHGAP28,BBC3,SERPINI1,DIRAS1,SPRY4,TPM1,NRP1,SPOCK3,MEF2C,LATS2,ALOX5AP,TBC1D1,ITGA6,SLK,DHCR24,OPHN1,GPSM2,TNFRSF10C,DYNC1I1,GRPEL2,IL17D,CHN1,FRY,CACNB2,MYC,FLRT3,PRELID1,SRGAP1,PRKG1,BOD1,HMGCR,EPB41L5,BDNF,DISC1,TBC1D8B,VLDLR,ARID5B,RYR2,HIP1,SMARCD3,ARRDC4,PLCB1,CLN5,FAM162A,MMP15,THBS4,INHBE,SMYD3,DOCK9,EPHA3,NBL1,BTC,PCSK1N,RASAL2,C4A,GPR65,PLXNA2,RGS20,ADD2,CHUK,LCP2,DDR1,TBC1D30,TIAM2,TLR3,DACT1,MAGEA3,DAB2IP,PDE4D,SERPINH1,SYNGR3,PERP,DOCK8,FZD1,GAPDH,ADM2,FZD4,PFKFB2,SHANK2,PREX1,ADCY1,PRKCQ,WNT11,ATP1B1,ASPH,TBC1D16,FGFR1,SNCA,IRS2,CXCL10,ARHGAP21,PRKCB,BEX3,WFS1,APELA,WWTR1,MAP3K21,TNFSF15,MAPK10,CGB2,MYO1D,SERINC5,FARP1,MXI1,EDA2R,FZD8,IPO5,ARL2,HERC5,GAS6,P2RY1,PKN1,EPHB1,RGS7,NDFIP2,TPD52L1,PHLDA2,NEDD4,LRRC55,RGS17,GHR,SGK3,RALGAPA2,TBC1D9,ERRFI1,GFI1,SPRY2,PARP9,VEGFC,VAV3,ARAP2,GSTM2,RAPGEF2,RASA3,RACK1,CTTNBP2NL,GPLD1,PTPRC,TRIB3,ID3,NSD1,FGR,TERT,GNAO1,BMP4,CERS1,DDIT3,ATP2B4,FOXA1,BTRC,PHACTR3,CACNG3,ACSL1,FGF13,HDGFL3,FAM13A,CACNB4,F3,ADPRHL1,SIPA1L2,PPM1E,KCNAB1,TCAF2,ITGB3,PCOLCE2,EPHB6,FANK1,TLR4,IL1RAP,SLIT2,PDGFRB,RASGRP1,PRKACB,LAMP3,CYP1B1,TNK2,SESN2,COL4A3,SPOCD1,ANK2,JPH1,ROR1,SGK2,INHBC,GSN,GPRC5B,ERN1,PPARGC1A,TNFSF4,NEUROG2,MAGI2,CACUL1,PCSK5,TYRO3,RGS16,FN1,STXBP5L,BVES,UBASH3B,ZIC2,PFN2,SPINK5,EFEMP1,RNF180,IGF1R,LRP6,ADCY6,INAVA,NOS3,PAK1,FGFR4,ATP5IF1,MID2,MSTN,GPSM1,EFNA3,STRADB,DUSP9,HERPUD1,TBC1D2,MAPKAPK2,RIPOR2,ADGRB3,CSF1,HEYL,SH3BP4,PTPRN2,TESC,SFN,PRKN,ID1,NEK10,AVPI1,DOCK1,IL15,ARHGAP22,HECW2,NTRK3,PIBF1,PPP1R9A,DOCK2,TBC1D19,CDC14B,BCL6,ACVR2A,PROS1,MET,HSPA2,CTH,IGFBP3,ALG10B,FER,CSN2,PTPN6,FGF12,GSTO1,CD40,WARS,CAMK2N1,SMAD3,RANBP2,NRG3,PTPRJ,TRIM34,KCNG1,ITGA2,RGS10,DUSP19,HGF,HEY1,ARFGEF3,TENM1,TNIK,LPAR2,IL32,ARHGEF11,PAK5,CMTM8,NLRP14,TNFSF13B,BMP6,PPP2R3A,ARHGAP44,SYDE2,NKX6-1,CHN2,SCN1B,PRKCD,STC2,EHD3,SGK1,AFAP1L2,SH3PXD2B,IQGAP3,TNFRSF11A,SYK,PCSK6,DUSP1,RIN2,MSX1,CRIM1,ASAP3,PHACTR2,AGAP2,ARHGAP32,CCNG1,TLR6,LEPR,MGMT,DKK1,SUGT1,DDAH1,DOCK7,EDA,FBN1,ACER2,MAP2K6,DLG2,GEM,TBC1D4,MAP3K20,MMP16,PKIA,CACNA2D1,STOM |
| 6.031e-05 | -9.72 | GO_POSITIVE_REGULATION_OF_CELL_COMMUNICATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_COMMUNICATION | 1485 | 190 | 17377 | 1707 |
ACVR1,LGR4,TRIM16,GRIK2,SYT12,VAMP8,LMCD1,GATA3,CTBP2,ABAT,PRKCA,NOS1AP,F3,SKI,TGFBR3,PMAIP1,ITGB3,HRK,TLR4,MYRIP,RASGRP1,PDGFRB,CYP1B1,GCNT2,SKAP2,WLS,TGFA,LRRK2,BNIP3L,YAP1,ACVR2B,INHBC,GSN,HPSE,GPRC5B,CCBE1,PLK2,ERN1,TNFRSF1A,BMP1,ADRB1,BBC3,DIRAS1,TMOD2,OXTR,UNC5B,NRP1,MLLT3,RRAGD,PRKAA2,SORBS3,SLC1A3,CHSY1,TNFRSF19,CHD5,IL18R1,CHN1,CA2,PIK3AP1,LRP6,BNIP3,RIMS2,ZNF385A,HMGCR,PAK1,FGFR4,MID2,BDNF,DISC1,SH2D2A,MSTN,WWC1,DUSP9,SNAP25,PLCB1,FAM162A,MAPKAPK2,ADAMTS3,CSF1,PELI2,INHBE,CDH2,SFN,NEK10,AVPI1,SORBS1,IL15,AKAP5,CHUK,NTRK3,NRXN1,PIBF1,TLR3,UNC13B,DACT1,ACVR2A,DAB2IP,CTH,GLI1,IGFBP3,INTU,PFKFB2,FZD4,PTPN6,SHANK2,PRKCQ,GSTO1,WNT11,ATF3,SYNJ2BP,CD40,ASPH,FGFR1,SNCA,SMAD3,IRS2,CXCL10,PTPRJ,PRKCB,ITGA2,DUSP19,GRB10,HGF,TNFSF15,DISP1,BMPR1A,ATG5,MAPK10,MID1,TNIK,BMPR2,C1QTNF3,EDA2R,GRB14,TSPAN15,REL,FZD8,EPS8,BIK,CLSTN2,GAS6,P2RY1,NDFIP2,PKN1,TPD52L1,BMP6,TSPAN17,NEDD4,PPP2R3A,MCU,NEO1,NKX6-1,CHN2,MCF2L,RASD2,GHR,PRKCD,AFAP1L2,DYNC2H1,IQGAP3,GFI1,TNFRSF11A,SPRY2,SYK,TRPM4,VAV3,RAB3B,MSX1,GSTM2,SH3BP2,RAPGEF2,LITAF,SKAP1,TLR6,GPLD1,DKK1,GPR37,PTPRC,FGR,NACC2,MPP7,TERT,MAP2K6,XBP1,LRRK1,BMP4,SHOX2,DDIT3,LARP1,FOXA1 |
| 6.042e-05 | -9.71 | growth cone | cellular component | GO:0030426 | 157 | 31 | 18223 | 1724 |
DBN1,GPM6A,FGF13,SHANK2,APBB1,EPS8,LRRK2,PREX1,KIF5C,FEZ1,NDRG2,SNAP25,KIF21B,PALLD,GDPD5,RAC3,PPP1R9A,TIAM2,SNCA,CCDC120,DOCK7,GPRIN1,MAP2,FLRT3,ADGRL1,TMOD2,CTTN,NRP1,NPTXR,COBL,SHTN1 |
| 6.071e-05 | -9.71 | YCATTAA_UNKNOWN | MSigDB lists | YCATTAA_UNKNOWN | 521 | 79 | 17377 | 1707 |
EXPH5,ACVR1,FGF13,LSM11,ARHGAP22,PLXNA2,GATA3,TUBE1,STAT5B,MGAT5B,IKZF2,NOVA1,SP8,PCDH7,TRPS1,RTN1,TUBB4A,ZNF827,PPM1E,KCTD15,UNC13B,LHX6,MPPED2,HRK,EPHB6,PDE4D,MYT1,CD55,MARK1,FZD4,KLHL4,NPM3,PRDM13,NFE2L1,SATB2,WNT11,TNS1,ENPP1,TCF7L1,BACH2,RASGRF2,ERN1,INPP4B,NRP1,CTNND2,RAB30,FRMD5,CHCHD7,KLHL13,RHOBTB1,PLAG1,CREB5,APBA1,SATB1,CHD5,MECOM,NEO1,FOXP2,ATXN7L1,C15orf41,FES,CKAP4,RAX,MSTN,FOXN3,ESRRG,PACSIN3,PRDM1,MBNL2,HOXA1,NSD1,ID3,PMEPA1,SH3BP4,DLG2,KIF21A,PAX9,SFN,DOCK9 |
| 6.166e-05 | -9.69 | kidney-carcinoma-renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-renal_cell_carcinoma | 4601 | 517 | 17385 | 1698 |
ARHGAP26,GRIK2,AASS,DNAJC3,MCOLN3,NPM1,STAT5B,CADM2,KIAA1217,SNX9,NOS1AP,SKI,PCDH7,BAG3,FBXO32,PMAIP1,PPFIA2,FAAH2,RAP2A,RAB26,TMED9,PPP2R2B,POU3F3,NKX2-1,MEIS2,SMAD9,TGFA,LRRK2,FEZ1,PRKAR2B,ABCC2,INTS6,ALDOA,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,LPP,MEF2C,CARS,GNG12,LATS2,ITGA6,BTBD9,GPSM2,FOXG1,BBS9,CHN1,BNIP1,APLF,CACNB2,SRGAP1,TOX,ALPK1,LOXL4,GFRA1,CHRM3,HMGCR,PNP,STAT4,EFHC2,HIP1,SMARCD3,DHX32,BEX4,ADAMTS3,HOXD13,SPRED3,FBXO27,TMSB15A,RGS20,IL13RA1,GRK6,COLEC10,NRXN1,RNF150,DACT1,ALDH1L1,FAM133A,PJA1,FAM155B,ARL4D,RAB27B,SNX10,FZD1,MYLK3,GAPDH,FZD4,WNT11,RAB38,METAP1D,FGFR1,GJC1,IRS2,CXCL10,ARHGAP21,INPP4B,PAM,TNFSF15,RAB30,FARP1,EDA2R,FZD8,PLAG1,BIK,IPO5,GAS6,PKN1,EPHB1,TSPAN17,BEX2,PCBP4,MCF2L,GAS2L3,GHR,ZFP36L2,MED12L,FES,BCL7A,RAB6B,MCF2L2,RAPGEF2,AK4,RASA3,SNTB1,PTPRC,TRIB3,ID3,GNAO1,AKT3,XBP1,NEK11,PIP5KL1,BMP4,HK1,BTRC,FOXA1,TRIM2,FGF13,TRIM16,ITPR2,NUP62CL,NOVA1,PLS3,RND2,FKBP9,RPS6KA2,ITGB3,ENO1,ETV1,RAPGEF5,ITGB7,MARK1,COL4A3,ANK2,CR2,PLEKHA1,BATF,SESN1,PLEKHB1,DYRK1B,TRIM9,KCNMB4,GNB4,ERN1,TNFRSF1A,PIK3C2B,MLLT3,RRAGD,KCNV1,PRKAA2,RGS16,RUNX2,DOK5,SPIRE1,HSPA12B,NUMBL,IGF1R,GATA2,LRP6,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,MID2,SPATA13,PPFIA4,STRADB,OBSCN,MAFB,KHDRBS2,MAPKAPK2,PLD1,RNF122,SFN,ID1,CFH,AKAP5,DOCK1,RNF24,ZNF83,NTRK3,LPIN3,PPP1R9A,SLC22A17,TACC2,MYO3B,BCL6,HRASLS,GLI1,ACO1,RNF125,VIM,FBXO36,FRK,PAGE5,SMAD3,RANBP2,PTPRJ,PTK7,ITGA2,PTPRS,MAOA,SEPT5,CTNND2,CNTN1,HEY1,DYRK3,BMPR2,KLHL13,GRB14,NLRP14,RASD1,USP30,PPP2R3A,FOXP2,RASD2,GTF2F2,SGK1,PCK2,SYK,ATP2B1,DUSP1,DLGAP1,PPP1R3D,FOXN3,CRIP2,LITAF,NUAK2,MGMT,DKK1,FAT4,FMO4,SH3BGRL2,PAX9,PTGES,MYCBP2,ACVR1,PAGE1,LANCL3,DUSP8,PPFIBP2,GATA3,ADAMTS6,PRKCA,DACH2,RAC3,HECTD2,STK24,SLC9A7,TRPS1,SLC16A2,CHRDL1,ACVR1C,KLHL4,LRMP,DNAJC6,DEPTOR,BNIP3L,ACVR2B,ZDHHC14,SAV1,GNAI1,AHRR,HLF,RASGRF2,PLK2,SERPINI1,MAPK13,SPRY4,UNC5B,KLF8,INPPL1,ALOX5AP,PTPRD,MLF1,ST6GAL1,OPHN1,TNFRSF10C,TNFRSF19,CHD5,GAS1,MECOM,NAV1,RALGPS2,ADCK1,NOVA2,MYC,PRKG1,MPDZ,SAMD13,RIMS2,RNF152,PTCH2,RPL26,PLEKHA8,TBC1D8B,RAPGEF4,CDC42BPA,PLCB1,FAM162A,TMEM74,MMP15,PKN3,PMEPA1,IQSEC2,DHCR7,SMYD3,AMPD1,FRMPD3,EPHA3,PLA2G4A,PCSK1N,RHOD,RNF144A,CHUK,COL14A1,DDR1,ZFYVE9,CCDC120,SPEG,ALDOC,STARD4,NAP1L3,PDE4D,SERPINH1,GAB2,TRDMT1,PDK1,PREX1,NLGN4X,ATF3,PNMA6A,PRKCQ,SATB2,ATOH1,PYGO1,ZNF711,IKZF3,PRKCB,CCNA1,GRB10,BMPR1A,STON2,MID1,HACE1,MXI1,HERC5,ARL2,RGS7,INPP1,NEDD4,RGS17,AFF2,SGK3,SLC6A15,SMAD6,SPRY2,VAV3,PXN,ALDH2,MPP1,PTPN13,ZDHHC15,GPLD1,CEBPB,FGR,TNFRSF17,DDIT3,NUDT17,PTPN21,IKZF2,HMCN1,KREMEN1,FKBP11,ARHGEF10L,PPM1E,AKAP7,POF1B,HRK,CTTN,PCOLCE2,PTPRE,PRKACB,PDGFRB,RASGRP1,TNK2,SESN2,YAP1,COTL1,TMEM47,ROR1,SGK2,RNF44,SERGEF,AK1,HPSE,NCOA7,PPARGC1A,TNFSF4,BCL11B,RHOBTB1,FBXO4,JDP2,SATB1,DDIT4,RNF141,RNF148,SNX7,PCDH10,RHOQ,SLITRK2,MSTN,DUSP9,SDC3,PRDM1,CSAG1,RAB31,HK2,PTPRN2,FNBP1L,NKX2-8,CXCR5,NEK10,PSTPIP2,PLEKHA5,ARHGAP22,COL18A1,MORC4,HECW2,BCL6B,DOCK2,UNC13B,CDC14B,RPS6KL1,PPFIBP1,ZNF521,ACVR2A,POU2F2,MET,HSPA2,SUSD3,PHLDB2,FER,PTPRU,PTPN6,CD40,BCL11A,MAGEA12,TRIM34,BACH2,KPNA3,EIF4EBP1,DUSP19,RGS10,RNF130,LIFR,MAST1,TNIK,ENO2,ARHGEF11,REL,TNFSF13B,IGF2BP2,COL4A5,CHN2,GTSF1,PRKCD,TRIM3,ACTA2,RRAS2,FKBP14,TNFRSF11A,CARD6,RIN2,USP2,RAB3B,CYTH3,SYBU,PRRG1,AGAP2,MARS,ARHGAP32,CCNG1,GALNT14,ADAMTS17,SUGT1,EDA,RND3,MAP2K6,GEM,RNF157,MMP16,IL9R |
| 6.166e-05 | -9.69 | renal_cell_carcinoma | COSMIC cancer mutations | renal_cell_carcinoma | 4601 | 517 | 17385 | 1698 |
ARHGAP26,GRIK2,AASS,DNAJC3,MCOLN3,NPM1,STAT5B,CADM2,KIAA1217,SNX9,NOS1AP,SKI,PCDH7,BAG3,FBXO32,PMAIP1,PPFIA2,FAAH2,RAP2A,RAB26,TMED9,PPP2R2B,POU3F3,NKX2-1,MEIS2,SMAD9,TGFA,LRRK2,FEZ1,PRKAR2B,ABCC2,INTS6,ALDOA,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,LPP,MEF2C,CARS,GNG12,LATS2,ITGA6,BTBD9,GPSM2,FOXG1,BBS9,CHN1,BNIP1,APLF,CACNB2,SRGAP1,TOX,ALPK1,LOXL4,GFRA1,CHRM3,HMGCR,PNP,STAT4,EFHC2,HIP1,SMARCD3,DHX32,BEX4,ADAMTS3,HOXD13,SPRED3,FBXO27,TMSB15A,RGS20,IL13RA1,GRK6,COLEC10,NRXN1,RNF150,DACT1,ALDH1L1,FAM133A,PJA1,FAM155B,ARL4D,RAB27B,SNX10,FZD1,MYLK3,GAPDH,FZD4,WNT11,RAB38,METAP1D,FGFR1,GJC1,IRS2,CXCL10,ARHGAP21,INPP4B,PAM,TNFSF15,RAB30,FARP1,EDA2R,FZD8,PLAG1,BIK,IPO5,GAS6,PKN1,EPHB1,TSPAN17,BEX2,PCBP4,MCF2L,GAS2L3,GHR,ZFP36L2,MED12L,FES,BCL7A,RAB6B,MCF2L2,RAPGEF2,AK4,RASA3,SNTB1,PTPRC,TRIB3,ID3,GNAO1,AKT3,XBP1,NEK11,PIP5KL1,BMP4,HK1,BTRC,FOXA1,TRIM2,FGF13,TRIM16,ITPR2,NUP62CL,NOVA1,PLS3,RND2,FKBP9,RPS6KA2,ITGB3,ENO1,ETV1,RAPGEF5,ITGB7,MARK1,COL4A3,ANK2,CR2,PLEKHA1,BATF,SESN1,PLEKHB1,DYRK1B,TRIM9,KCNMB4,GNB4,ERN1,TNFRSF1A,PIK3C2B,MLLT3,RRAGD,KCNV1,PRKAA2,RGS16,RUNX2,DOK5,SPIRE1,HSPA12B,NUMBL,IGF1R,GATA2,LRP6,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,FGFR4,MID2,SPATA13,PPFIA4,STRADB,OBSCN,MAFB,KHDRBS2,MAPKAPK2,PLD1,RNF122,SFN,ID1,CFH,AKAP5,DOCK1,RNF24,ZNF83,NTRK3,LPIN3,PPP1R9A,SLC22A17,TACC2,MYO3B,BCL6,HRASLS,GLI1,ACO1,RNF125,VIM,FBXO36,FRK,PAGE5,SMAD3,RANBP2,PTPRJ,PTK7,ITGA2,PTPRS,MAOA,SEPT5,CTNND2,CNTN1,HEY1,DYRK3,BMPR2,KLHL13,GRB14,NLRP14,RASD1,USP30,PPP2R3A,FOXP2,RASD2,GTF2F2,SGK1,PCK2,SYK,ATP2B1,DUSP1,DLGAP1,PPP1R3D,FOXN3,CRIP2,LITAF,NUAK2,MGMT,DKK1,FAT4,FMO4,SH3BGRL2,PAX9,PTGES,MYCBP2,ACVR1,PAGE1,LANCL3,DUSP8,PPFIBP2,GATA3,ADAMTS6,PRKCA,DACH2,RAC3,HECTD2,STK24,SLC9A7,TRPS1,SLC16A2,CHRDL1,ACVR1C,KLHL4,LRMP,DNAJC6,DEPTOR,BNIP3L,ACVR2B,ZDHHC14,SAV1,GNAI1,AHRR,HLF,RASGRF2,PLK2,SERPINI1,MAPK13,SPRY4,UNC5B,KLF8,INPPL1,ALOX5AP,PTPRD,MLF1,ST6GAL1,OPHN1,TNFRSF10C,TNFRSF19,CHD5,GAS1,MECOM,NAV1,RALGPS2,ADCK1,NOVA2,MYC,PRKG1,MPDZ,SAMD13,RIMS2,RNF152,PTCH2,RPL26,PLEKHA8,TBC1D8B,RAPGEF4,CDC42BPA,PLCB1,FAM162A,TMEM74,MMP15,PKN3,PMEPA1,IQSEC2,DHCR7,SMYD3,AMPD1,FRMPD3,EPHA3,PLA2G4A,PCSK1N,RHOD,RNF144A,CHUK,COL14A1,DDR1,ZFYVE9,CCDC120,SPEG,ALDOC,STARD4,NAP1L3,PDE4D,SERPINH1,GAB2,TRDMT1,PDK1,PREX1,NLGN4X,ATF3,PNMA6A,PRKCQ,SATB2,ATOH1,PYGO1,ZNF711,IKZF3,PRKCB,CCNA1,GRB10,BMPR1A,STON2,MID1,HACE1,MXI1,HERC5,ARL2,RGS7,INPP1,NEDD4,RGS17,AFF2,SGK3,SLC6A15,SMAD6,SPRY2,VAV3,PXN,ALDH2,MPP1,PTPN13,ZDHHC15,GPLD1,CEBPB,FGR,TNFRSF17,DDIT3,NUDT17,PTPN21,IKZF2,HMCN1,KREMEN1,FKBP11,ARHGEF10L,PPM1E,AKAP7,POF1B,HRK,CTTN,PCOLCE2,PTPRE,PRKACB,PDGFRB,RASGRP1,TNK2,SESN2,YAP1,COTL1,TMEM47,ROR1,SGK2,RNF44,SERGEF,AK1,HPSE,NCOA7,PPARGC1A,TNFSF4,BCL11B,RHOBTB1,FBXO4,JDP2,SATB1,DDIT4,RNF141,RNF148,SNX7,PCDH10,RHOQ,SLITRK2,MSTN,DUSP9,SDC3,PRDM1,CSAG1,RAB31,HK2,PTPRN2,FNBP1L,NKX2-8,CXCR5,NEK10,PSTPIP2,PLEKHA5,ARHGAP22,COL18A1,MORC4,HECW2,BCL6B,DOCK2,UNC13B,CDC14B,RPS6KL1,PPFIBP1,ZNF521,ACVR2A,POU2F2,MET,HSPA2,SUSD3,PHLDB2,FER,PTPRU,PTPN6,CD40,BCL11A,MAGEA12,TRIM34,BACH2,KPNA3,EIF4EBP1,DUSP19,RGS10,RNF130,LIFR,MAST1,TNIK,ENO2,ARHGEF11,REL,TNFSF13B,IGF2BP2,COL4A5,CHN2,GTSF1,PRKCD,TRIM3,ACTA2,RRAS2,FKBP14,TNFRSF11A,CARD6,RIN2,USP2,RAB3B,CYTH3,SYBU,PRRG1,AGAP2,MARS,ARHGAP32,CCNG1,GALNT14,ADAMTS17,SUGT1,EDA,RND3,MAP2K6,GEM,RNF157,MMP16,IL9R |
| 6.196e-05 | -9.69 | V$IK2_01 | MSigDB lists | V$IK2_01 | 253 | 45 | 17377 | 1707 |
TYRO3,PHACTR3,CGN,CACNG3,IGFBP6,BMPR2,FGF13,SORBS3,SLCO3A1,ARHGAP44,CYP26A1,ATXN7L1,SPEG,IGF1R,RALGPS2,TACC2,PPFIA2,TFAP2A,ADCY6,ETV1,RBMS2,POU3F3,MN1,BDNF,MSX1,GPM6A,USP2,TES,PRDM13,AGPAT4,NFIA,PRDM1,ACVR2B,FGF17,ZFPM2,GUCY1A2,BCL11A,KLF12,MAP2K6,TNFSF15,RNF122,FNBP1L,PKIA,CNTN1,HS6ST3 |
| 6.207e-05 | -9.69 | Interactions of neurexins and neuroligins at synapses | REACTOME pathways | R-HSA-6794361 | 58 | 16 | 10287 | 971 |
DLGAP1,EPB41L5,SYT12,SHANK2,HOMER2,BEGAIN,NLGN4X,NRXN1,APBA1,HOMER3,EPB41L3,LIN7A,DLG2,GRIN2D,STXBP1,APBA2 |
| 6.214e-05 | -9.69 | left_upper_lobe | COSMIC cancer mutations | left_upper_lobe | 574 | 85 | 17385 | 1698 |
FAM171B,EXPH5,CACNG3,FAM13A,PCLO,FSTL5,SKI,TRPS1,COL22A1,SIPA1L2,TGFBR3,TM9SF2,DACT1,ZDHHC6,ALDH1L1,MPPED2,GSTM3,COL19A1,DAB2IP,CTH,VNN2,B3GALT1,CSN2,ADM2,JPH1,PREX1,METAP1D,ARHGAP21,PRKCB,MAP2,MAP9,LAMB1,BMP1,DNHD1,CTTNBP2,NR3C2,COBL,LIFR,CTNND2,LRFN5,IL32,PTPRD,LRP4,GABRG2,EPHB1,BCHE,FRAS1,GHR,RUNDC3B,PRKG1,SLC6A15,TBC1D9,NCAM1,GFI1,JAM2,ZNF518B,KIAA1211,CES3,SNX7,ZNF629,DLGAP1,CDH26,PCDH10,CACNA1E,ARID5B,EFHC2,KIAA1324L,RYR2,HIP1,SDK1,ARHGAP32,GUCY1A2,ZFPM2,PLCB1,TMEM74,ZIC1,GPR37,CACHD1,FAT4,EMILIN2,CDH2,OSBPL6,CACNA2D1,DOCK9,ATP1A3 |
| 6.223e-05 | -9.68 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN | 187 | 36 | 17377 | 1707 |
FRMPD3,GPR63,RGS16,AKAP5,ATP9A,GTF2IRD1,P2RY1,NDFIP2,IL18R1,NIPSNAP3B,MTUS1,SKI,EPB41L3,FUT9,CDC14B,MYO3B,MAP7,IPCEF1,ST8SIA1,MYRIP,SLC40A1,CARD6,PHLDB2,NR6A1,ATF7IP2,EXOG,CD40,TBC1D16,CTIF,CAMK2N1,SLC39A14,AKT3,ZBTB20,RPL4,NRP1,RRAGD |
| 6.232e-05 | -9.68 | undifferentiated_carcinoma | COSMIC cancer mutations | undifferentiated_carcinoma | 1431 | 183 | 17385 | 1698 |
ARHGAP26,THOC5,ACVR1,FGF13,STAT5B,PRKCA,DNER,KREMEN1,STK24,HECTD2,FBXO32,RPS6KA2,PMAIP1,RAP2A,PPP2R2B,TLN2,ETV1,TLR4,TSHR,PRKACB,PDGFRB,NKX2-1,DBN1,ACVR1C,TGFA,YAP1,PRKAR2B,ROR1,FGF17,ACVR2B,SGK2,SAV1,RNF44,TCF7L1,GPRC5B,SH3RF1,RASGRF2,TNFRSF1A,ADRB1,BBC3,MAPK13,ERCC5,PIK3C2B,DIRAS1,SPRY4,NRP1,TMEFF2,MAGI2,MLLT3,LPP,MEF2C,BCL11B,PRKAA2,CARS,LATS2,INPPL1,CELSR1,PTPRD,JDP2,MLF1,RASL11B,FOXG1,MECOM,SYCP2,NUMBL,OTUD1,IGF1R,MYC,LRP6,NOS3,PAK1,FGFR4,PTCH2,IL17RD,STAT4,HIP1,CALCRL,MAFB,DUSP9,STEAP1,MAPKAPK2,SQLE,EGFL7,HOXD13,PLD1,CDH2,SFN,CXCR5,EPHA3,PLA2G4A,BTC,CFH,RHOD,HECW2,CHUK,NTRK3,DDR1,RADIL,TLR3,BCL6,ACVR2A,MET,FZD1,IGFBP3,GAB2,PDK1,RNF145,FZD4,PTPN6,FGF12,ATF3,PRKCQ,WNT11,CD40,FGFR1,MAGI3,BCL11A,IRS2,RANBP2,NRG3,IKZF3,PRKCB,PTK7,EIF4EBP1,GRB10,BMPR1A,SEPT5,LIFR,CNTN1,HACE1,HEY1,LPAR2,BMPR2,IGFBP6,PLAG1,REL,FZD8,SSX1,TNFSF13B,HERC5,RASD1,P2RY1,PKN1,EPHB1,USP30,PPP2R3A,NEDD4,PRKCD,GHR,RASD2,SGK3,SGK1,RRAS2,SYK,SPRY2,TNFRSF11A,MED12L,DUSP1,PARP9,MN1,RIN2,VAV3,BCL7A,PPP1R3D,PXN,USP2,RAPGEF2,RASA3,UCHL3,GUCY1A2,TLR6,MGMT,DKK1,GPR37,RND3,GNAO1,AKT3,MAP2K6,BMP4,TNFRSF17,GEM,BTRC,DDIT3 |
| 6.266e-05 | -9.68 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | 314 | 53 | 17377 | 1707 |
ARHGAP26,LPAR2,SCAMP1,FLVCR2,PTPRD,MORC4,ASS1,COL18A1,NRN1,CTBP2,NTRK3,ABAT,SPATS2L,SEL1L3,DDR1,RGS17,FRY,CDC14B,STC2,TFAP2A,MARCH3,JAKMIP2,TBC1D9,MET,TMEM120B,SMPDL3A,PCSK6,PGBD5,FGFR4,GCA,ANK2,CRIP2,RAPGEF4,ACO1,NLGN4X,SATB2,PRKAR2B,TMEM47,KCND3,SLC46A3,SESN1,BCL11A,WARS,IFT81,GYPC,POPDC3,AKT3,MAGI2,COBL,KIF1B,ABCG1,DOCK9,RRAGD |
| 6.302e-05 | -9.67 | GO_REGULATION_OF_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_ION_TRANSPORT | 571 | 85 | 17377 | 1707 |
CACNG3,AKAP5,ATP8A1,VAMP8,LILRB1,PKP2,GRK6,ABAT,NRXN1,CACNB4,NOS1AP,KCNN2,KCNAB1,AKAP7,CNKSR3,KCNS3,TRPC1,TMEM37,PDE4D,SCN2A,HSPA2,SCN3A,PDGFRB,KCNB2,DPP10,KCNIP3,ATF4,KCNH5,ANK2,PTPN6,JPH1,FGF12,CHRNA6,GSTO1,AMIGO1,KCND3,ATP1B1,SGK2,ASPH,SNCA,IRS2,CXCL10,WFS1,KCNG1,ATG5,PPARGC1A,CNTN1,MEF2C,KCNV1,SCN5A,LGALS3,UBASH3B,SCN8A,NKAIN2,P2RY1,KCNC4,NEDD4,KCNJ4,CA2,SCN1B,CACNB2,PRKCD,STC2,PRELID1,SGK3,SGK1,TSPAN13,TNFRSF11A,SYK,NOS3,RAB3B,GSTM2,KCNQ3,CACNA1E,PACSIN3,RYR2,KCNK15,GNAO1,MAP2K6,BMP4,TRPC3,TESC,CACNA2D1,ATP2B4,STOM |
| 6.326e-05 | -9.67 | GO_FOREBRAIN_DEVELOPMENT | MSigDB lists | GO_FOREBRAIN_DEVELOPMENT | 353 | 58 | 17377 | 1707 |
TYRO3,BCL11B,SCN5A,GNG12,ROBO2,FGF13,AKAP5,OTX1,BCAN,GDPD5,CHD5,RAC3,PGAP1,SKI,FOXP2,NUMBL,EOMES,GATA2,TACC2,LHX6,PRKG1,LRP6,DAB2IP,DYNC2H1,DNAH5,SLIT2,POU3F3,GLI1,NKX2-1,RAX,DISC1,MSX1,RAPGEF2,VLDLR,LRRK2,SLITRK5,SATB2,EFHC1,ATOH1,PLCB1,FGFR1,TSKU,DKK1,NRG3,DOCK7,FAT4,GNAO1,LAMB1,PTPRS,DLX2,OXTR,BMPR1A,BMP4,NRP1,PPARGC1A,CDH2,SEMA3A,ATP2B4 |
| 6.413e-05 | -9.65 | V$TGIF_01 | MSigDB lists | V$TGIF_01 | 231 | 42 | 17377 | 1707 |
EPHA3,MXI1,INPPL1,DNM3,ACVR1,GCAT,VAMP8,CLSTN2,APBA1,TNFRSF19,TNKS1BP1,IKZF2,DYNC1I1,PRRG4,NEDD4,DDIT4,TUBB4A,FOXP2,ABLIM1,UNC13B,IKZF5,ALDOC,PCBP4,GTF2F2,ACVR2A,PPP2R2B,C15orf41,POU3F3,GAB2,RNF152,PPP1R3D,JPH1,CALCRL,WWC1,OBSCN,SESN1,WARS,BMP1,NXPH4,SERPINI1,RPL4,FNBP1L |
| 6.428e-05 | -9.65 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP | 152 | 31 | 17377 | 1707 |
MPZL3,PLA2G4A,EPB41L5,SLC40A1,CD55,PTPRD,STAT4,HOMER2,DCHS1,KIAA1324L,GATA3,TMEM200C,STRADB,ABHD6,GNAI1,RTN1,ATPAF2,ZFYVE28,CSF1,REEP1,ZNF704,CCDC122,SGK1,MAOA,TNFRSF17,RAB27B,SHOX2,ZNF365,CSRP2,PKIA,GAB2 |
| 6.454e-05 | -9.65 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP | 166 | 33 | 17377 | 1707 |
GPR63,LATS2,VAV3,CD55,SIDT1,RNF145,PDE1B,FGF13,RNF144A,CRIM1,NR4A1,RAPGEF4,SELL,COBLL1,RASA3,PDE8A,MFSD6,CD7,KBTBD11,TNKS1BP1,SMPDL3B,SMAD3,SLC7A1,OTUD1,BACH2,PRKCB,GPR155,RUNDC3B,HS3ST3B1,POU2F2,ERRFI1,KIF1B,ATP2B1 |
| 6.456e-05 | -9.65 | neuronal cell body | cellular component | GO:0043025 | 457 | 69 | 18223 | 1724 |
PDE1B,GRIK2,C4A,KIF5A,ASS1,CANX,NRXN1,DNER,RAC3,PPP1R9A,TUBB4A,KCNAB1,KCNN2,DAB2IP,CPE,KCNB2,GPM6A,SHANK2,LRRK2,FEZ1,EFHC1,PRKAR2B,KCND3,AMIGO1,CD40,TTLL7,SNCA,CAMK2N1,MAP2,RGS10,PAM,PTPRS,INPP5F,SERPINI1,BMPR1A,PPARGC1A,NRP1,COBL,CTNND2,PRKAA2,MYO1D,ENO2,BMPR2,LRP4,APBB1,SLC25A27,KIF5C,SLC1A3,KCNC4,GDPD5,MAP1A,PDE10A,LRP6,NPTXR,ZNF385A,ATP2B1,DPYSL5,TRPM4,MYO10,RAPGEF2,HOMER2,RACK1,BAIAP2,MAP1B,SH3GL2,CTSV,SHTN1,SNPH,ATP1A3 |
| 6.462e-05 | -9.65 | SERVITJA_ISLET_HNF1A_TARGETS_UP | MSigDB lists | SERVITJA_ISLET_HNF1A_TARGETS_UP | 159 | 32 | 17377 | 1707 |
PLA2G4A,SV2B,DNM3,STXBP5L,LGALS3,FGF13,BLVRB,ASS1,COL18A1,NDRG2,FSTL5,EFEMP1,SEMA4F,HPS1,ZNF521,SCARF2,PRKG2,SLC6A15,SERPINH1,SNAI2,CYP1B1,OPLAH,MEIS2,RAB6B,VIM,ATF3,TMEM47,RAB38,SNCA,SMAD3,FBN1,CSF1 |
| 6.472e-05 | -9.65 | BERENJENO_TRANSFORMED_BY_RHOA_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_DN | 369 | 60 | 17377 | 1707 |
MYO1D,MRC2,FN1,RECK,HEBP1,CD276,CYP4V2,ENAH,COL4A5,ITPR2,GAS6,TTC30B,GAS1,CYP51A1,FKBP9,ABLIM1,HMGCS1,GHR,LRP6,GSTM3,MARCKS,KLF9,PCK2,PLTP,SMAD6,HSPA2,RBMS2,SNAI2,PDGFRB,FZD1,CYP1B1,RIN2,GSTM2,COL6A2,PNP,MYO10,WLS,PTPN13,MVD,MGST3,TCEA3,C1R,RABAC1,NPC2,TLR6,SESN1,FGFR1,EBF1,ID3,GSN,IFT81,TCF7L1,NACC2,MATN2,MAOA,GRB10,SLC1A5,DHCR7,CSRP2,DDIT3 |
| 6.545e-05 | -9.63 | Protein_kinase_ATP_BS | interpro domains | IPR017441 | 378 | 61 | 18492 | 1811 |
EPHA3,PRKAA2,TYRO3,TNIK,LATS2,NEK10,ACVR1,DYRK3,BMPR2,PAK5,SLK,CHUK,NTRK3,MAPK4,GRK6,PRKCA,EPHB1,PKN1,STK24,MOK,SPEG,RPS6KA2,IGF1R,PRKCD,SGK3,PRKG1,MYO3B,PRKG2,SGK1,MET,SYK,PDGFRB,PRKACB,FES,PAK1,FGFR4,FER,TNK2,MYLK3,MARK1,ACVR1C,LRRK2,NUAK2,OBSCN,PRKCQ,CDC42BPA,SGK2,FRK,GRK3,FGFR1,DYRK1B,MAPKAPK2,FGR,PRKCB,PKN3,MAP2K6,PLK2,AKT3,MAP3K21,MAPK13,BMPR1A |
| 6.569e-05 | -9.63 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | 45 | 14 | 17377 | 1707 |
TGFBR3,ID1,GATA2,P4HA2,DNAJC3,MYC,HK2,SGK1,WNT11,CCNG1,SLCO3A1,CYP26A1,FZD1,HOPX |
| 6.644e-05 | -9.62 | MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 | MSigDB lists | MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 | 409 | 65 | 17377 | 1707 |
MYCBP2,PDE1B,NTRK3,SLC2A13,DOCK3,BCAN,CBLN1,LGI2,EPB41L3,NELL2,SERINC2,PACSIN1,TMEM132E,MYRIP,SLIT2,POU3F3,GLDC,DBN1,DPP10,PRDM13,FGF12,KCND3,TCERG1L,BATF3,HTR7,NRG3,GNB4,ITGA2,GRB10,OXTR,TC2N,SCN5A,NECAB2,CLGN,SCN8A,BIK,LAMC3,CLSTN2,EPHB1,KCNC4,BEX2,BMP6,CHD5,NKX6-1,KCNJ4,C1QL4,EBF4,GRIP1,FAR2,NPTXR,FAM155A,COL9A2,BARX1,RAX,PODXL2,KCNQ3,RAB6B,ELOVL3,GRID1,MAFB,PDE8A,SKAP1,ZIC1,KCNK15,SIX2 |
| 6.674e-05 | -9.61 | GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT | 224 | 41 | 17377 | 1707 |
EPHA3,FN1,ROBO2,BMPR2,PTPRD,AKAP5,APBB1,NTRK3,PPP1R9A,RND2,NUMBL,SCN1B,SGK1,DAB2IP,MARCKS,FIG4,PACSIN1,SLIT2,RIMS2,FES,DISC1,BDNF,RAPGEF2,VLDLR,FEZ1,AMIGO1,FGFR1,CPEB1,BAIAP2,MAP1B,BCL11A,NEGR1,GPRC5B,PTK7,HGF,BMP4,NRP1,SHOX2,MAGI2,COBL,CNTN1 |
| 6.687e-05 | -9.61 | tissue development | biological process | GO:0009888 | 1660 | 205 | 17256 | 1658 |
EXPH5,ACVR1,LGR4,MCOLN3,ACTL8,GATA3,STAT5B,DNER,SKI,EPCAM,TGFBR3,KCNAB1,EOMES,GRHL1,DLX6,MARVELD2,ITGB3,RAP2A,TBC1D32,POF1B,GSTM3,COL19A1,SLIT2,POU3F3,PRKACB,PDGFRB,NKX2-1,CYP1B1,SMAD9,KLHL3,WLS,YAP1,ACVR2B,SAV1,ARHGEF26,DYRK1B,GSN,ENPP1,HLF,BDH2,BMP1,SEMA3C,DLX2,NRP1,TPM1,TMEFF2,SPART,PPARGC1A,MAGI2,MEF2C,BCL11B,RUNX2,LGALS3,FN1,CELSR1,BVES,ITGA6,DHCR24,OPHN1,TJP1,CHSY1,SATB1,PHGDH,SPINK5,TNFRSF19,MYORG,FHOD3,EEF2,SLC7A11,CA2,SEMA4F,PDZD7,GATA2,FRAS1,MYC,FLRT3,LRP6,TOX,BARX1,EPB41L5,PAK1,PTCH2,ENAM,MSTN,DCHS1,ARID5B,FHL2,RYR2,PRDM1,MMP15,RIPOR2,CSF1,HEYL,CECR2,WDR19,SELENOM,HOXD13,SEMA3A,CDH2,SIX2,SFN,CREB3L2,TFCP2L1,ZNF516,ID1,ST14,PLXNA2,PKP2,COL18A1,NTRK3,DDR1,SETDB2,DACT1,ALDOC,KAZN,ACVR2A,MYH15,PDE4D,MET,SERPINH1,PERP,SNAI2,GLI1,FZD1,INTU,MYLK3,SOX21,NKX3-2,SATB2,VIM,ATF3,WNT11,CBY1,ATOH1,DSP,FGFR1,GJC1,SMAD3,MSC,IKZF3,POPDC3,PTK7,APELA,WWTR1,ITGA2,LAMB1,PTPRS,KLF5,HGF,BMPR1A,ATG5,COBL,HEY1,EDA2R,ROBO2,BMPR2,LRP4,OVOL2,BMP6,PPP2R3A,COL27A1,NKX6-1,FOXP2,DSG2,STC2,TFAP2A,ACTA2,SH3PXD2B,ERRFI1,PCK2,SMAD6,SPRY2,PCSK6,DUSP1,VEGFC,B9D1,MICAL2,SLC40A1,MSX1,KDM5B,RAPGEF2,PRICKLE1,ZFPM2,FNDC3A,PALLD,MGMT,HEG1,DKK1,GPLD1,PTPRC,CEBPB,ID3,MYADM,EDA,FAT4,CTSV,XBP1,TUFT1,SVIL,MYOM2,PAX9,BMP4,SHOX2,FOXA1,BTRC |
| 6.797e-05 | -9.60 | positive regulation of phosphorus metabolic process | biological process | GO:0010562 | 1129 | 147 | 17256 | 1658 |
ACSL1,ACVR1,FGF13,PRKCA,SNX9,STK24,GSDME,RAP2A,ITGB3,EPHB6,TLR4,TSHR,ENO1,PRKACB,RASGRP1,PDGFRB,TNK2,GCNT2,TGFA,LRRK2,PRKAR2B,ACVR2B,ROR1,INHBC,GPRC5B,NCKAP1L,ERN1,ADRB1,TNFRSF1A,DIRAS1,NRP1,PPARGC1A,MAGI2,CACUL1,MEF2C,PRKAA2,TYRO3,ITGA6,SLK,SORBS3,TNFRSF10C,PFN2,TNFRSF19,IGF1R,ADCY6,INAVA,GPR161,NOS3,HMGCR,PAK1,FGFR4,MSTN,VLDLR,DUSP9,WWC1,STRADB,PDE8A,PLCB1,MAPKAPK2,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,EPHA3,AVPI1,NEK10,IL15,NTRK3,LCP2,TNKS1BP1,DDR1,PIBF1,PPP1R9A,TLR3,ACVR2A,DAB2IP,MET,HSPA2,IGFBP3,FZD1,PFKFB2,FZD4,ADCY1,WNT11,RARRES2,CD40,FGFR1,SNCA,SMAD3,CXCL10,NRG3,APELA,ITGA2,DUSP19,MAP3K21,TNFSF15,HGF,BMPR1A,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,LRP4,GAS6,P2RY1,PKN1,EPHB1,TPD52L1,BMP6,PRKCD,GHR,AFAP1L2,IQGAP3,TNFRSF11A,SYK,SPRY2,PARP9,PFKFB4,VEGFC,MOB1B,VAV3,RAPGEF2,GAREM1,AGAP2,RACK1,GUCY1A2,TLR6,GPLD1,DKK1,GPR37,PTPRC,FGR,DOCK7,MAP2K6,LRRK1,BMP4,MAP3K20,ATP2B4 |
| 6.797e-05 | -9.60 | positive regulation of phosphate metabolic process | biological process | GO:0045937 | 1129 | 147 | 17256 | 1658 |
ACSL1,ACVR1,FGF13,PRKCA,SNX9,STK24,GSDME,RAP2A,ITGB3,EPHB6,TLR4,TSHR,ENO1,PRKACB,RASGRP1,PDGFRB,TNK2,GCNT2,TGFA,LRRK2,PRKAR2B,ACVR2B,ROR1,INHBC,GPRC5B,NCKAP1L,ERN1,ADRB1,TNFRSF1A,DIRAS1,NRP1,PPARGC1A,MAGI2,CACUL1,MEF2C,PRKAA2,TYRO3,ITGA6,SLK,SORBS3,TNFRSF10C,PFN2,TNFRSF19,IGF1R,ADCY6,INAVA,GPR161,NOS3,HMGCR,PAK1,FGFR4,MSTN,VLDLR,DUSP9,WWC1,STRADB,PDE8A,PLCB1,MAPKAPK2,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,EPHA3,AVPI1,NEK10,IL15,NTRK3,LCP2,TNKS1BP1,DDR1,PIBF1,PPP1R9A,TLR3,ACVR2A,DAB2IP,MET,HSPA2,IGFBP3,FZD1,PFKFB2,FZD4,ADCY1,WNT11,RARRES2,CD40,FGFR1,SNCA,SMAD3,CXCL10,NRG3,APELA,ITGA2,DUSP19,MAP3K21,TNFSF15,HGF,BMPR1A,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,LRP4,GAS6,P2RY1,PKN1,EPHB1,TPD52L1,BMP6,PRKCD,GHR,AFAP1L2,IQGAP3,TNFRSF11A,SYK,SPRY2,PARP9,PFKFB4,VEGFC,MOB1B,VAV3,RAPGEF2,GAREM1,AGAP2,RACK1,GUCY1A2,TLR6,GPLD1,DKK1,GPR37,PTPRC,FGR,DOCK7,MAP2K6,LRRK1,BMP4,MAP3K20,ATP2B4 |
| 6.799e-05 | -9.60 | BILD_HRAS_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_HRAS_ONCOGENIC_SIGNATURE | 239 | 43 | 17377 | 1707 |
LPAR2,FN1,ITPRIP,ELOVL7,LDLR,PLXNA2,INPP1,PHLDA2,GAS1,COL27A1,MTUS1,ZNF827,FLRT3,SMTN,BCL6,TSC22D1,SLC6A15,PTPRE,MAST4,ATP2B1,RNF152,DUSP1,CYP1B1,PNMA2,CD55,SESN2,TGFA,DNAJC6,MBNL2,LRAT,TMEM154,HPSE,MFSD2A,ITGA2,CCNA1,HK2,AHNAK2,KLF5,SPRY4,TPM1,MBOAT2,MID1,SFN |
| 6.817e-05 | -9.59 | GO_CELLULAR_RESPONSE_TO_ORGANIC_SUBSTANCE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ORGANIC_SUBSTANCE | 1779 | 222 | 17377 | 1707 |
CGN,ACVR1,ACSL1,PDE1B,DNAJC3,GATA3,LILRB1,ASS1,NPM1,CEBPA,STAT5B,ITPR2,AARS,F3,SKI,FBXO32,TGFBR3,RPS6KA2,AKAP7,CHRDL1,TLR4,TSHR,SLIT2,IL1RAP,PRKACB,PDGFRB,CYP1B1,GCNT2,ATF4,SMAD9,NR6A1,LRRK2,YAP1,FEZ1,PRKAR2B,ACVR2B,KCND3,FGF17,GNAI1,ENPP1,GNB4,ERN1,TNFRSF1A,BMP1,OXTR,NRP1,TNFSF4,PPARGC1A,MAGI2,RRAGD,MEF2C,PRKAA2,LATS2,GNG12,RUNX2,FN1,GABRB2,ATP6V1E2,TNFRSF10C,MLC1,TNFRSF19,IL18R1,GAS1,RPL13A,DDIT4,NUMBL,CA2,IGF1R,EEF2,FLRT3,SREBF1,LRP6,ADCY6,GRIP1,NCAM1,NOS3,FGFR4,EPB41L5,PAK1,IL17RD,RHOQ,MSTN,VLDLR,EDEM3,FASN,FHL2,CALCRL,RYR2,PLCB1,CPEB1,BAIAP2,HERPUD1,MAPKAPK2,PMEPA1,CSF1,HEYL,SH3BP4,RAB31,PTPRN2,TESC,SMYD3,MME,CXCR5,CREB3L2,EPHA3,ID1,SORBS1,IL15,AKAP5,RBFOX2,MSR1,RGS20,NTRK3,IL13RA1,CHUK,ZFYVE9,TLR3,ASNS,ACVR2A,DAB2IP,PDE4D,SNAI2,CTH,FZD1,FER,MYLK3,GAPDH,UROS,FZD4,FGF12,ADCY1,SATB2,WNT11,ATF3,CD40,FGFR1,SNCA,ISG20,SMAD3,IRS2,CXCL10,TRIM34,PRKCB,GBP1,PTK7,EIF4EBP1,WFS1,ITGA2,HPGD,TNFSF15,HGF,GRB10,BMPR1A,LIFR,NR3C2,MID1,HEY1,PLSCR4,BMPR2,ROBO2,EDA2R,ESRP1,LRP4,IPO5,TNFSF13B,GABRG2,P2RY1,GAS6,BMP6,NEDD4,NKX6-1,RAB11FIP5,HMGCS1,BHLHA15,PRKCD,STC2,GHR,GTF2F2,SGK1,KLF9,IQGAP3,ERRFI1,GFI1,SMAD6,TNFRSF11A,FKBP14,SYK,ATP2B1,DUSP1,MSX1,GSTM2,PXN,KDM5B,HNF4G,NR4A1,RAPGEF2,ESRRG,LITAF,FERMT2,LEPR,MGMT,GPLD1,CEBPB,GALNT3,TRIB3,ID3,TERT,FBN1,PLOD2,MAP2K6,XBP1,PAX9,BMP4,CERS1,TNFRSF17,CMPK2,TBC1D4,IL9R,DDIT3,BTRC,ATP2B4,ATP1A3 |
| 6.822e-05 | -9.59 | HALLMARK_IL2_STAT5_SIGNALING | MSigDB lists | HALLMARK_IL2_STAT5_SIGNALING | 195 | 37 | 17377 | 1707 |
RGS16,TTC39B,BMPR2,GPR65,ITGA6,SELL,IKZF2,SNX9,IL18R1,NCS1,HOPX,CA2,IGF1R,EOMES,MYC,SMPDL3A,CKAP4,PNP,SLC39A8,WLS,GSTO1,BATF,GABARAPL1,BATF3,MAPKAPK2,CXCL10,ENPP1,PLAGL1,CSF1,XBP1,HK2,P4HA1,SH3BGRL2,SPRY4,NRP1,SLC1A5,RRAGD |
| 6.822e-05 | -9.59 | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | MSigDB lists | HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION | 195 | 37 | 17377 | 1707 |
IL32,ENO2,FN1,IL15,FZD8,PFN2,GAS1,TGFBR3,ABI3BP,ITGB3,ACTA2,PCOLCE2,SERPINH1,SLIT2,PDGFRB,SNAI2,IGFBP3,VEGFC,BDNF,QSOX1,MSX1,COL6A2,CAP2,FERMT2,VIM,SNTB1,DKK1,PMEPA1,FBN1,PLOD2,ITGA2,MATN2,BMP1,OXTR,GEM,TPM1,CDH2 |
| 6.822e-05 | -9.59 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | 195 | 37 | 17377 | 1707 |
CXCR5,MYCBP2,TMEM132C,PSTPIP2,YPEL2,CADM2,COL27A1,SCIN,CPNE2,RNF180,RALGPS2,ADCK1,ABCA5,PRELID2,RAB26,ACVR2A,MET,TSPAN9,BARX1,GFRA1,PARP9,CHSY3,SYNPO2,CTTNBP2NL,ARHGAP32,SDK1,C3orf70,SLC46A3,HOXA1,TRIB3,GNB4,THSD7B,DLG2,CMPK2,NRP1,DIRC2,FRMD5 |
| 6.859e-05 | -9.59 | BASSO_HAIRY_CELL_LEUKEMIA_DN | MSigDB lists | BASSO_HAIRY_CELL_LEUKEMIA_DN | 80 | 20 | 17377 | 1707 |
RIN2,TBKBP1,ARAP2,TRIM2,RECK,SLITRK5,SDC3,KCTD12,CTBP2,NOVA1,FGFR1,CPVL,PLOD2,SCN1B,WWTR1,TNFRSF1A,MAPK10,SPRY2,SMPDL3A,IGFBP3 |
| 6.943e-05 | -9.58 | regulation of actin filament organization | biological process | GO:0110053 | 252 | 44 | 17256 | 1658 |
TENM1,PRKN,ID1,TMSB15A,GPR65,EPS8,ADD2,SORBS3,PFN2,RAC3,PPP1R9A,FHOD3,SPIRE1,SCIN,ARHGEF10L,PPM1E,PRKCD,CTTN,SH3PXD2B,MET,SLIT2,PAK1,SSH3,FER,PHLDB2,SYNPO2,EVL,PXN,DSTN,ASAP3,PREX1,WNT11,BAIAP2,SMAD3,GSN,PLEKHH2,MYADM,NCKAP1L,WIPF3,ARHGAP28,TMOD2,TPM1,NRP1,TMEFF2 |
| 6.943e-05 | -9.58 | kidney development | biological process | GO:0001822 | 252 | 44 | 17256 | 1658 |
ROBO2,LGR4,LRP4,GATA3,ASS1,BMP6,EPCAM,RIDA,CA2,ZNF354A,FRAS1,MYC,TFAP2A,ACTA2,SMAD6,SLIT2,POU3F3,PDGFRB,SMAD9,COL4A3,KLHL3,COL4A4,DCHS1,LRRK2,ARID5B,WNT11,ACVR2B,PYGO1,FGFR1,SMAD3,ID3,FAT4,FBN1,WFS1,HEYL,WWTR1,HPGD,BMP4,NRP1,MAGI2,MME,SIX2,MEF2C,PCSK5 |
| 6.983e-05 | -9.57 | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN | MSigDB lists | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN | 188 | 36 | 17377 | 1707 |
ACSL1,TTC39B,FLVCR2,BLVRB,SEL1L3,TPD52L1,ABHD6,TTC1,TMEM53,SIPA1L2,RPS11,KAZN,EEPD1,TSC22D1,MORN2,JAKMIP2,FHIT,VWA5A,TLR4,SLC45A3,PGBD5,VNN2,SPOCD1,VLDLR,ATF3,SNTB1,GABARAPL1,C11orf45,TBC1D2,FGR,PRKCB,WFS1,DISP1,STON2,MME,PHC1 |
| 6.983e-05 | -9.57 | CTTGTAT,MIR-381 | MSigDB lists | CTTGTAT,MIR-381 | 188 | 36 | 17377 | 1707 |
EPHA3,BCL11B,RNF144A,ELOVL7,CEBPA,NRXN1,SATB1,MECOM,SIPA1L2,KCTD15,FLRT3,EIF1,NBEA,ACVR2A,TLN2,GFRA1,C15orf41,RHOQ,MEIS2,PNRC1,JPH1,SHANK2,NFIA,ZFPM2,MBNL2,BCL11A,NAP1L5,KPNA3,INSIG1,KLF12,FCHO2,SEMA3C,IQSEC2,KIF1B,PURG,LARP1 |
| 6.988e-05 | -9.57 | SENESE_HDAC2_TARGETS_DN | MSigDB lists | SENESE_HDAC2_TARGETS_DN | 112 | 25 | 17377 | 1707 |
GXYLT2,STOX2,TRIM2,IGFBP6,RHOBTB1,CAP2,ZCCHC24,GSTM4,PKP2,TMEM200C,SCD,ZNF362,FKBP9,INSIG1,MPP7,DACT1,MATN2,SQLE,ZBTB20,RTKN2,PPP2R2B,TMEM37,NPTXR,TPM1,PSPH |
| 6.992e-05 | -9.57 | GO_SOMATODENDRITIC_COMPARTMENT | MSigDB lists | GO_SOMATODENDRITIC_COMPARTMENT | 631 | 92 | 17377 | 1707 |
DNM3,PDE1B,FGF13,PRSS12,GRIK2,AKAP5,KIF5A,ASS1,NRXN1,CANX,BCAN,DNER,RAC3,PPP1R9A,NCS1,TUBB4A,NELL2,KCNN2,KCNAB1,CHRNA5,DAB2IP,MARCKS,CTTN,CPE,SCN3A,KCNB2,DBN1,GPM6A,KCNIP3,WLS,SHANK2,LRRK2,PREX1,NLGN4X,FEZ1,PRKAR2B,EFHC1,AMIGO1,KCND3,TTLL7,GABARAPL1,TRIM9,CAMK2N1,PLK2,WFS1,PAM,BMPR1A,NRP1,PPARGC1A,MAGI2,CTTNBP2,COBL,LZTS1,CTNND2,MYO1D,FARP1,ENO2,BMPR2,LRP4,APBB1,OPHN1,P2RY1,SLC1A3,EPHB1,GDPD5,ARHGAP44,KCNJ4,PDE10A,GRIP1,LRP6,BNIP3,MPDZ,ATP2B1,CHRM3,ZNF385A,DPYSL5,TRPM4,PAK1,MYO10,RAPGEF2,HOMER2,ARHGAP32,CPEB1,BAIAP2,MAP1B,ICA1,RPL28,GNAO1,SEMA3A,MME,ATP1A3,SNPH |
| 6.999e-05 | -9.57 | regulation of small GTPase mediated signal transduction | biological process | GO:0051056 | 338 | 55 | 17256 | 1658 |
ARHGAP26,FARP1,RASAL2,RHOBTB1,ARHGEF11,RHOD,GPR65,EPS8,ARHGAP22,OPHN1,PSD3,FAM13A,RAC3,TIAM2,ARHGAP44,SYDE2,CHN1,ARHGEF10L,SIPA1L2,CHN2,RALGPS2,MCF2L,SRGAP1,BCL6,RALGAPA2,DAB2IP,MET,SLIT2,SPRY2,PDGFRB,RASGRP1,VAV3,ARAP2,RHOQ,ARHGEF28,MCF2L2,CYTH3,ASAP3,SPATA13,PREX1,RASA3,OBSCN,AGAP2,ARHGAP32,ARHGEF26,ARHGAP21,RIPOR2,RASGRF2,CSF1,PLEKHG1,ARHGAP28,SPRY4,IQSEC2,NRP1,ARFGEF3 |
| 7.045e-05 | -9.56 | digestive tract development | biological process | GO:0048565 | 128 | 27 | 17256 | 1658 |
EPB41L5,LGR4,NKX3-2,ITGA6,DCHS1,GATA3,ASS1,WNT11,PRDM1,ACVR2B,OVOL2,RARRES2,SAV1,SMAD3,FAT4,GATA2,DACT1,RBPMS2,KLF5,HOXD13,BMP4,OXTR,SHOX2,COBL,SIX2,PCSK5,GLI1 |
| 7.049e-05 | -9.56 | GO_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_CYTOSKELETON_ORGANIZATION | 775 | 109 | 17377 | 1707 |
ARHGAP26,UGT8,SORBS1,FGF13,DOCK1,RHOD,PSTPIP2,GPR65,MYO1B,PKP2,ADD2,NPM1,COBLL1,TUBE1,PIBF1,DOCK2,RAC3,PCLO,SEMA6A,PPP1R9A,SCIN,EPB41L3,LRRC6,PDZD8,TACC2,RAP2A,BCL6,MAP7,MARCKS,CTTN,PACSIN1,TLN2,DNAH5,PDGFRB,DBN1,FER,PHLDB2,GAPDH,EVL,MYLK3,MARK1,CAP2,DSTN,PREX1,VIM,DSP,EML1,ARMC4,GSN,PDLIM3,NCKAP1L,MAP2,WIPF3,PTK7,PLK2,ALDOA,MAP9,TMOD2,TPM1,MID1,COBL,MAST1,WASF3,TNIK,INPPL1,ARHGEF11,SLK,EPS8,OPHN1,ARL2,SORBS3,GPSM2,PFN2,FHOD3,SPIRE1,ABLIM1,NAV1,MAP1A,FRY,GAS2L3,GAN,PRKG1,SGK1,LIMCH1,FIGN,MAST4,SPRY2,FMNL2,FES,PDLIM7,PAK1,EPB41L5,MICAL2,DISC1,RHOQ,NUAK2,OBSCN,PLS1,CDC42BPA,PALLD,BAIAP2,MAP1B,DOCK7,RND3,FAT1,CECR2,SVIL,IQSEC2,NPHP1 |
| 7.128e-05 | -9.55 | LEE_NEURAL_CREST_STEM_CELL_UP | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_UP | 139 | 29 | 17377 | 1707 |
MSX1,SORBS1,MSTN,ZCCHC24,C3orf52,LITAF,COBLL1,ROR1,SNAP25,NRXN1,COL14A1,CYP26A1,QPRT,GSN,CHN2,KCNN2,GYPC,BCHE,DACT1,PCBP4,LAMB1,TFAP2A,SEMA3C,MOXD1,LZTS1,CEBPD,SNAI2,SCN3A,MEF2C |
| 7.141e-05 | -9.55 | PROTEIN_KINASE_DOM | prosite domains | PS50011 | 480 | 78 | 12060 | 1278 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PDGFRB,PRKACB,FER,TNK2,MYLK3,MARK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,GRK3,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAP3K21,MAPK13,BMPR1A,MAPK10,MAST1,TYRO3,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,IGF1R,PRKCD,PRKG1,SGK3,SGK1,PRKG2,MAST4,SYK,FES,FGFR4,PAK1,NUAK2,OBSCN,STRADB,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,MAP2K6,AKT3,NEK11,LRRK1,MAP3K20 |
| 7.147e-05 | -9.55 | GO_AXON | MSigDB lists | GO_AXON | 402 | 64 | 17377 | 1707 |
DNM3,FGF13,PRSS12,GRIK2,CADM2,NRXN1,CANX,SEMA6A,NCS1,CTNNA2,TUBB4A,EPB41L3,UNC13B,KCNAB1,DAB2IP,MARCKS,PACSIN1,SCN2A,SCN3A,ATL1,GPM6A,GARS,KCNIP3,DCC,LRRK2,FEZ1,GSTO1,AMIGO1,SNCA,NCAM2,ITGA2,SEPT5,NRP1,COBL,MYO1D,ROBO2,BACE1,SCN8A,APBB1,OPHN1,GABRG2,EPHB1,PFN2,KCNC4,GDPD5,CNTN4,CA2,SCN1B,FLRT3,STXBP1,CHRM3,PAK1,DISC1,KCNQ3,SDC3,PALLD,DAGLA,DOCK7,PTPRN2,DLG2,SEMA3A,KIF1B,MME,ATP1A3 |
| 7.179e-05 | -9.54 | WENG_POR_TARGETS_LIVER_UP | MSigDB lists | WENG_POR_TARGETS_LIVER_UP | 40 | 13 | 17377 | 1707 |
CYP51A1,ANTXR2,GSTM2,ASNS,IDI1,HMGCS1,MSMO1,UGDH,DHCR24,GSTM3,SQLE,SCD,CYP26A1 |
| 7.179e-05 | -9.54 | GO_STEROL_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_STEROL_BIOSYNTHETIC_PROCESS | 40 | 13 | 17377 | 1707 |
CYP51A1,PRKAA2,IDI1,MVK,HMGCS1,INSIG1,MSMO1,MVD,CYB5R2,DHCR24,SQLE,DHCR7,HMGCR |
| 7.199e-05 | -9.54 | TATAAA_V$TATA_01 | MSigDB lists | TATAAA_V$TATA_01 | 1203 | 158 | 17377 | 1707 |
TRIM2,PTPN21,NDRG2,SLCO3A1,NOS1AP,EOMES,ABI3BP,CHRDL1,MPPED2,GSTM3,COL19A1,PLTP,ETV1,PRKACB,MEIS2,ATF4,SMAD9,SKAP2,DSTN,JPH1,PLEKHA1,MFSD6,GPC6,MAP9,TIGD4,SEMA3C,ZBTB20,CAB39L,DIRAS1,PPARGC1A,PRKAA2,LRFN5,SEMA6B,RUNX2,FN1,PTPRD,CHCHD7,RHOBTB1,SCN8A,GABRB2,SLC25A27,OPHN1,RASL11B,SPINK5,MTUS1,EFEMP1,ABLIM1,CA2,CNTN4,EEF2,ADCK1,MYC,SAMD11,ZIC5,TSPAN12,BNIP3,RNF148,TSPAN9,GFRA1,PTCH2,MID2,ENAM,BDNF,MSTN,SLC27A2,MGST3,HOMER2,RAPGEF4,FHL2,PACSIN3,STRADB,AIG1,PRDM1,ZBBX,SNAP25,NPC2,CLN5,GRIK4,PMEPA1,KIAA0355,TMEM117,NKX2-8,SEMA3A,AMPD1,NEK10,ID1,RASAL2,RBFOX2,PLXNA2,SP8,CYP26A1,CTNNA2,ZNF827,KCTD15,FABP6,LHX6,BCL6,MYO3B,FAM133A,NAP1L3,ARL4D,SSH3,GAPDH,TES,PANK1,SATB2,FBXO36,JAM3,HTR7,ZNF711,SMAD3,MSC,BACH2,PDLIM3,TDO2,P4HA1,RCN3,MID1,CGB2,CNTN1,FARP1,C1QTNF3,KLHL13,PLAG1,FZD8,CREB5,BEX2,NEDD4,ATXN7L1,FOXP2,HMGCS1,TFAP2A,TSC22D1,KCNMB3,PRKG2,TSPAN13,C15orf41,TRPM4,ARAP2,ESRRG,NR4A1,AGPAT4,FOXN3,CCNG1,SKAP1,MAP1B,DKK1,CEBPB,GALNT3,ID3,PLOD2,RND3,MAP2K6,DLG2,GEM,TNFRSF17,SHOX2,FOXA1 |
| 7.226e-05 | -9.54 | GSE16385_MONOCYTE_VS_MACROPHAGE_DN | MSigDB lists | GSE16385_MONOCYTE_VS_MACROPHAGE_DN | 174 | 34 | 17377 | 1707 |
MYCBP2,PPP4R4,GABRB2,ITGA6,IGF2BP2,NUDT12,NIPSNAP3B,TIAM2,NAV1,TLR3,KCNN2,ABCA5,TRPC1,CADPS2,CTTN,PTPRE,MYRIP,THSD1,PRKACB,DZANK1,MN1,RPL26,CDH26,BDNF,FAM84A,SYNJ2BP,MBNL2,STEAP1,NAALADL2,HLF,NCAM2,MMP16,CTNND2,MEF2C |
| 7.331e-05 | -9.52 | response to organic substance | biological process | GO:0010033 | 2888 | 334 | 17256 | 1658 |
CGN,ACVR1,PDE1B,DNAJC3,LDLR,GATA3,NPM1,CEBPA,STAT5B,CHAC1,PRKCA,SKI,FBXO32,TGFBR3,PMAIP1,CHRDL1,TSHR,NKX2-1,GLDC,GDAP1,MEIS2,SMAD9,NR6A1,ACVR1C,LRRK2,FEZ1,PRKAR2B,AGO4,ABCC2,FGF17,F12,ACVR2B,GNAI1,ENPP1,MAPK13,NRP1,MEF2C,LATS2,GNG12,INPPL1,GABRB2,ITGA6,DHCR24,TNFRSF10C,TNFRSF19,GAS1,RPL13A,FLRT3,MYC,SREBF1,GRIP1,NCAM1,STXBP1,AGL,CHRM3,HMGCR,EPB41L5,BDNF,STAT4,MGST3,EFHC2,ARID5B,FASN,FHL2,CALCRL,RYR2,PLCB1,CPEB1,MMP15,SH3GL2,PMEPA1,PELI2,THBS4,SQLE,HOXD13,TRPC3,SMYD3,AMPD1,EPHA3,IL13RA1,MAPK4,CHUK,ZFYVE9,PLPP1,TLR3,ASNS,KMO,DAB2IP,PDE4D,SERPINH1,SNX10,DOCK8,GAB2,TRDMT1,MYLK3,GAPDH,COL6A2,FZD4,PFKFB2,ADCY1,SATB2,WNT11,ATF3,FGFR1,ISG20,SNCA,IRS2,CXCL10,PEMT,WFS1,ASIC1,PAM,HPGD,TNFSF15,KLF5,BMPR1A,MAPK10,NR3C2,MID1,CGB2,PLSCR4,EDA2R,ROBO2,ESRP1,IPO5,GPR180,GAS6,P2RY1,NEDD4,HMGCS1,BHLHA15,GHR,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,ZFP36L2,VEGFC,TRPM4,PXN,GSTM2,PTPN13,RAPGEF2,GAREM1,RACK1,GPLD1,CEBPB,GALNT3,ID3,TRIB3,TERT,GNAO1,XBP1,BMP4,CMPK2,TNFRSF17,CERS1,FOXA1,BTRC,OCLN,ATP2B4,DDIT3,LARP1,ATP1A3,ACSL1,TRIM16,ASS1,LILRB1,ABAT,ITPR2,F3,GSDME,PCOLCE2,TLR4,SLIT2,IL1RAP,PDGFRB,PRKACB,LAMP3,CYP1B1,SLC3A2,SESN2,ATF4,GCNT2,ANK2,YAP1,BATF,SESN1,GSN,INSIG1,MAP2,GNB4,ERN1,TNFRSF1A,OXTR,PPARGC1A,TNFSF4,MAGI2,RRAGD,PRKAA2,RUNX2,FN1,HID1,ATP6V1E2,MLC1,IL18R1,DDIT4,NUMBL,EEF2,ZNF354A,IGF1R,CA2,BCHE,GATA2,ADCY6,INAVA,LRP6,CEBPD,NOS3,FGFR4,PAK1,IL17RD,RHOQ,MSTN,HOMER2,EDEM3,PDE8A,SDK1,BAIAP2,HERPUD1,MAPKAPK2,RIPOR2,CSF1,HEYL,SH3BP4,RAB31,HK2,PTPRN2,TESC,MME,CREB3L2,CXCR5,PRKN,ID1,SORBS1,IL15,RBFOX2,NTRK3,CANX,CYP26A1,RIDA,UNC13B,BCL6,ACVR2A,HSPA2,SNAI2,CTH,FER,TMEM67,EVL,UROS,PTPRU,PTPN6,FGF12,VIM,GSTO1,CD40,SMAD3,MSC,TRIM34,PTK7,EIF4EBP1,GBP1,ITGA2,RGS10,MAOA,HGF,LIFR,PSPH,HEY1,IL32,BMPR2,REL,LRP4,TNFSF13B,SELL,GABRG2,HBE1,BMP6,NKX6-1,RAB11FIP5,FOXP2,DSG2,PRKCD,STC2,GTF2F2,KLF9,IQGAP3,PCK2,ESD,TNFRSF11A,SYK,FKBP14,ATP2B1,DUSP1,MSX1,KDM5B,HNF4G,NR4A1,ESRRG,NUGGC,LITAF,FERMT2,MARS,TLR6,ILDR2,LRAT,LEPR,MGMT,DKK1,EDA,FAT4,FBN1,MAP2K6,ACER2,CTSV,PAX9,TBC1D4,KIF1B,PTGES,IL9R,CACNA2D1,ABCG1 |
| 7.368e-05 | -9.52 | renal system development | biological process | GO:0072001 | 268 | 46 | 17256 | 1658 |
ROBO2,LGR4,ITGA6,LRP4,GATA3,ASS1,BMP6,EPCAM,RIDA,CA2,ZNF354A,FRAS1,MYC,TFAP2A,ACTA2,SMAD6,SLIT2,POU3F3,PDGFRB,SMAD9,COL4A3,KLHL3,COL4A4,DCHS1,LRRK2,ARID5B,NFIA,WNT11,ACVR2B,PYGO1,FGFR1,SMAD3,ID3,FAT4,FBN1,WFS1,HEYL,WWTR1,HPGD,BMP4,NRP1,MAGI2,MME,SIX2,MEF2C,PCSK5 |
| 7.383e-05 | -9.51 | RICIN | smart domains | SM00458 | 27 | 11 | 9493 | 1056 |
GALNT3,GALNT1,MRC2,GALNT6,GALNT12,CRYBG1,GALNT13,GALNT17,GALNT14,GALNT18,CRYBG3 |
| 7.411e-05 | -9.51 | ATGCTGC,MIR-103,MIR-107 | MSigDB lists | ATGCTGC,MIR-103,MIR-107 | 203 | 38 | 17377 | 1707 |
LATS2,TBKBP1,ZHX3,KIF5A,PLAG1,GABRG2,PSD3,FAM117B,SPATS2L,FAM81A,NOVA1,SIPA1L2,LRRC55,TGFBR3,AFF2,SRGAP1,MARCH3,JAKMIP2,PACSIN1,BDNF,NFIA,RNF125,SATB2,ZFPM2,GPC6,ZIC1,BCL11A,DCBLD2,ZNF711,HLF,BACH2,ITGA2,RAI14,DSEL,KIF21A,FNBP1L,CACNA2D1,BTRC |
| 7.439e-05 | -9.51 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP | 316 | 53 | 17377 | 1707 |
DMXL2,SERINC5,LPAR2,ALOX5AP,FLVCR2,PDE1B,ST14,PSTPIP2,TNFSF13B,ANKRD18A,ABAT,CREB5,SEZ6L2,MCOLN2,GBGT1,SLC7A11,HPS1,TMEM86A,FIG4,IPCEF1,PROS1,RCAN3,DENND1C,STXBP1,AGL,ATP6AP1L,PARP9,ANKRD20A3,ANKRD20A2,QSOX1,ITGB7,ALDH2,CACNA1E,GSTM4,RPL21,ATF7IP2,PRKAR2B,EFHC1,PRDM1,SLC46A3,ATP10D,PTPRC,CD37,ZNF93,RPL28,NCAM2,PRKCB,PRCP,PLXDC2,CCDC146,PLD1,RNF130,RRAGD |
| 7.512e-05 | -9.50 | TTAYRTAA_V$E4BP4_01 | MSigDB lists | TTAYRTAA_V$E4BP4_01 | 240 | 43 | 17377 | 1707 |
PRKAA2,SIDT1,RBFOX2,MCTP2,PRDM8,GABRR2,CREB5,SYT14,IKZF2,ARHGAP44,ZFYVE9,HECTD2,FRY,GRHL1,FUT9,LHX6,BCL6,TSC22D1,PRKG1,KLF9,MED12L,ENAM,UNC5C,GPM6A,ERGIC1,USP2,RNF145,CRIM1,PRICKLE1,MSRB3,ZDHHC14,MBNL2,HERPUD1,NEGR1,BCL11A,DAGLA,SMAD3,SH3GL2,MAP2K6,PELI2,MPP2,SPRY4,OSBPL6 |
| 7.629e-05 | -9.48 | V$HNF3ALPHA_Q6 | MSigDB lists | V$HNF3ALPHA_Q6 | 196 | 37 | 17377 | 1707 |
TYRO3,BCL11B,FARP1,ID1,FGF13,CHCHD7,PLAG1,TJP1,CADM2,LCP2,NOVA1,HMCN1,NEO1,FOXP2,KCTD15,CHRDL1,SGK3,SGK1,PDE4D,ERRFI1,SSH3,GPM6A,GCNT2,MSTN,SLC39A8,PACSIN3,NFIA,PRDM1,ATOH1,C4orf19,BAIAP2,GABARAPL1,KLF12,AKT3,GNAO1,MCC,MEF2C |
| 7.698e-05 | -9.47 | KONDO_EZH2_TARGETS | MSigDB lists | KONDO_EZH2_TARGETS | 218 | 40 | 17377 | 1707 |
UST,MYO1D,TRIM2,CNTNAP3,ATP9A,ITGA6,PRSS35,LMCD1,IL13RA1,DNER,PCLO,EPB41L3,ABCA5,ABI3BP,SGK1,GULP1,KLF9,LOXL4,SCN2A,FAR2,CPE,PRR16,IGFBP3,ANTXR2,RAB3B,CAP2,GPC6,C9orf116,NEGR1,HLF,ITGBL1,WWTR1,HPGD,DSEL,SPRY4,DLX2,NRP1,SUSD4,CRISPLD1,RRAGD |
| 7.705e-05 | -9.47 | GO_SYNAPTIC_SIGNALING | MSigDB lists | GO_SYNAPTIC_SIGNALING | 411 | 65 | 17377 | 1707 |
DOC2A,AKAP5,GRIK2,KIF5A,SYT12,SYT14,NRXN1,CACNB4,NOVA1,RAC3,PCLO,CBLN1,PPP1R9A,UNC13B,CHRNA5,PPFIA2,LIN7A,LRRK2,FGF12,CHRNA6,GJC1,SNCA,HTR7,TRIM9,KCNMB4,RGS10,PTPRS,TMOD2,SEPT5,APBA2,TC2N,MEF2C,LRFN5,SLC6A9,PTPRD,GABRB2,GABRG2,SLC12A6,SLC1A3,GABRR2,APBA1,KCNC4,PCDHB14,SCN1B,CACNB2,RASD2,KCNMB3,LRP6,CADPS2,STXBP1,CHRM3,RIMS2,DLGAP1,GPR176,KCNQ3,CACNA1E,SLITRK5,SNAP25,PLCB1,GRIK4,PTPRN2,DLG2,GRIN2D,KIF1B,SNPH |
| 7.732e-05 | -9.47 | MODULE_248 | MSigDB lists | MODULE_248 | 126 | 27 | 17377 | 1707 |
FER,RGS16,GRB14,ARHGEF11,MPP1,STAT4,PTPN6,PTPN13,RASA3,PRKCQ,GUCY1A2,PRKCA,APBA1,EML1,EFEMP1,ABLIM1,CHN2,FGR,UNC13B,PDLIM3,FBN1,WFS1,LIN7A,GRB10,MPDZ,FES,CYP1B1 |
| 7.826e-05 | -9.46 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | 189 | 36 | 17377 | 1707 |
PHACTR3,RGS16,INPPL1,ZNF516,FN1,LPCAT2,RUSC2,CD276,PSD3,IGF2BP2,FAM198B,SATB1,SLC7A11,TACC2,MCF2L,PRELID2,KIAA0319,CNNM2,TSPAN13,CTTN,STXBP1,PTPRE,PDE8A,PLEKHA1,CD40,MFSD6,SMPDL3B,DCBLD2,PLAGL1,PMEPA1,PRKCB,SLC2A6,C1orf21,PTPRS,XKR4,STON2 |
| 7.826e-05 | -9.46 | GSE5589_WT_VS_IL6_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | 189 | 36 | 17377 | 1707 |
MRC2,AVPI1,RUNX2,PDE1B,IGFBP6,PLEKHA5,HEBP1,PKP2,SCD,NEDD4,PCDH7,CYP51A1,CDC14B,PRICKLE2,PCOLCE2,CPE,SYK,PHLDB2,TMEM65,MGAT4B,CRIP2,WDR25,GSTO1,FRK,EML1,FGFR1,TBC1D2,ENPP1,DOCK7,CCBE1,PLXDC2,MAOA,GRB10,PIP5KL1,CDH2,PANK3 |
| 7.826e-05 | -9.46 | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | 189 | 36 | 17377 | 1707 |
FGF13,ST6GAL1,CYP4V2,SELL,SFXN3,SATB1,ABHD4,DNER,SLCO3A1,IL18R1,CCDC120,RASSF8,RPS6KA2,CA2,SLC30A4,KMO,BCL6,ACVR2A,ADCY6,GRIP1,KLF9,SPRY2,EIF4E3,LRRK2,DEPTOR,VIM,ZDHHC14,MMP15,IRS2,IFT81,GPRC5B,TRIM34,SH3GL2,WFS1,ZBTB20,LPP |
| 7.878e-05 | -9.45 | regulation of synapse organization | biological process | GO:0050807 | 164 | 32 | 17256 | 1658 |
DNM3,ROBO2,PTPRD,LRP4,CLSTN2,NTRK3,EPHB1,NRXN1,PPP1R9A,CBLN1,CTNNA2,NEDD4,ARHGAP44,ADGRB2,LRRN1,FLRT3,ADGRL1,DAB2IP,IL1RAP,BDNF,LZTS3,SLITRK2,LRRK2,SLITRK5,AMIGO1,BAIAP2,DKK1,SNCA,ADGRB3,OXTR,CDH2,MEF2C |
| 7.930e-05 | -9.44 | protein binding | molecular function | GO:0005515 | 11470 | 1188 | 17224 | 1680 |
ARHGAP26,THOC5,GRIK2,RECK,NPM1,CTBP2,CEBPA,SNX9,TENT5C,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,SMIM20,KLHL23,DCC,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,INPP5F,DIRAS1,TPM1,DNHD1,SCN5A,ITGA6,TJP1,BTBD9,GPSM2,BBS9,FOXG1,HPCAL4,CHN1,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,FHL2,FASN,HIP1,AIG1,SNAP25,ARRDC4,CLN5,SPATA7,GSTO2,RPL28,SELENOM,CLMN,LAPTM4B,CDH2,SHTN1,DOCK9,SCAMP1,ADD2,MAPK4,GRK6,SLC19A2,TLR3,MAGEA3,FAM133A,ZNF365,DNAH5,SNX10,KCNB2,FZD1,COL6A2,GAPDH,LRRC75A-AS1,PFKFB2,ADM2,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,APELA,LAMB1,CGB2,CCDC148,BACE1,FZD8,ESRP1,CD276,BIK,UBAC2,PSD3,CBS,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,RAB6B,ATP11A,NSD1,RPL12,NEK11,BMP4,ATP2B4,PHC1,PHACTR3,FGF13,TRIM16,NDRG2,ITPR2,MGAT5B,PLS3,RND2,CPNE2,RUFY4,RPS6KA2,AADAT,ITGB3,MPPED2,JAKMIP2,ENO1,RAPGEF5,DBN1,KCNIP3,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,CR2,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,NEUROG2,TC2N,CACUL1,RRAGD,LONRF1,TYRO3,RUNX2,STXBP5L,LGALS3,HID1,SORBS3,PFN2,FHOD3,SPIRE1,RNF180,NUMBL,ZBTB38,ZNF440,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,VGLL4,DPYSL5,BTNL9,EFNA3,GPSM1,MAFB,STRADB,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,PLD1,SEMA3A,SMCO4,ID1,DOCK1,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,TACC2,BCL6,MYH15,SNAI2,IGFBP3,RPS13,INTU,LRRC8B,TDRD3,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,HGF,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,KIZ,NECAB2,BMPR2,PAK5,PRDM8,RASD1,TTC1,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,KIAA0408,SYK,ATP2B1,PCSK6,DUSP1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,HOMER3,DKK1,EBF1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,KIF1B,PKIA,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,TRPS1,TYMP,ZFYVE28,PALD1,GLDC,ERGIC1,ACVR1C,WISP3,KLHL3,BNIP3L,EFHC1,GNAI1,SH3RF1,BMP1,MAPK13,SPRY4,NRP1,SEMA6B,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,APBA1,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,MYC,C1QL4,SCARF2,SREBF1,PRKG1,GRIP1,PRR16,BOD1,PTCH2,RPL26,DISC1,VLDLR,RAPGEF4,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,WDR19,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,SMYD3,NBL1,TCTN2,RHOD,CCDC110,PLXNA2,MSR1,TMEM170B,COL14A1,DDR1,TIAM2,ZFYVE9,CCDC120,SPEG,ASNS,ERG28,ALDOC,SHF,PDE4D,GAB2,CYB5R2,SHANK2,PREX1,NLGN4X,ATF3,SATB2,CBY1,ATP1B1,PYGO1,ATOH1,ATP10D,C9orf116,SNCA,PATJ,ZNF711,IKZF3,BEX3,TDO2,CCNA1,HPGD,BMPR1A,MID1,COBL,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,KIF5C,HERC5,NDFIP2,TPD52L1,INPP1,ADGRB2,GSAP,ATXN7L1,RASSF8,LRRC55,RMDN2,DYNC2H1,TBC1D9,ERRFI1,SMAD6,SLC40A1,VAV3,SH3BP2,PXN,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,UCHL3,HOXA1,TERT,PLXDC2,MCC,SVIL,LRRK1,DDIT3,LARP1,ACTL8,PTPN21,C20orf194,F3,ADPRHL1,EPCAM,PPM1E,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,TNK2,SESN2,SKAP2,CEMIP2,YAP1,COTL1,GSN,GPRC5B,HPSE,PPARGC1A,TNFSF4,MAGI2,FRMD5,PCSK5,SV2B,MOCOS,RHOBTB1,BVES,FBXO4,STXBP6,PCDHB14,FAM27E3,EEF2,SLC30A4,INAVA,LIMCH1,VSIR,CAND2,CEBPD,SNX7,CDH26,HBG2,ATP5IF1,PODXL2,RHOQ,GSTM4,SDC3,HERPUD1,RIPOR2,FAT1,NCR3LG1,SH3BP4,NXPH4,FNBP1L,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COBLL1,CANX,PIBF1,SCIN,CD53,CDC14B,ERO1B,KAZN,PPFIBP1,REEP1,ACVR2A,FHIT,TMEM120B,NTNG1,PRAME,ANTXR2,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,CD40,ZNF569,BATF3,CAMK2N1,MAGEA12,KPNA3,EIF4EBP1,RBPMS2,RGS10,DUSP19,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,SLX1B,IGF2BP2,FAM117B,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,AFAP1L2,TESPA1,PNMA2,CARD6,USP2,KDM5B,CRIM1,SYBU,ASAP3,CCDC184,PEAK1,TLR6,NAALADL2,LEPR,CTIF,SUGT1,ICA1,EDA,RND3,CTSV,UACA,IL9R,NATD1,NPHP1,ABCG1,DOC2A,PDE1B,LSM11,DNAJC3,CADM2,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,BAG3,CDR2L,TGFBR3,PPP1R26,FBXO32,PMAIP1,DNAH6,PPFIA2,RAB26,GGACT,TSHR,NKX2-1,MEIS2,SMAD9,GJB2,TGFA,CAP2,WLS,MSRB3,F12,ZNF266,ALDOA,CRYL1,LPP,MEF2C,CARS,LATS2,GNG12,SLK,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,CACNB2,LOXL4,NCAM1,STXBP1,AGL,FMNL2,GFRA1,CHRM3,LRP12,RPS23,HMGCR,BDNF,ENAM,MYO10,MGST3,STAT4,CALCRL,SMARCD3,RYR2,PLS1,C1R,TAF4B,DHX32,BEX4,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,CSRP2,BTC,NUDT10,DNM3,ZNF516,TMSB15A,FAM131C,C4A,MYO1B,BEGAIN,RGS20,PKP2,IL13RA1,LCP2,NRXN1,COLEC10,GPR15,EPB41L3,CHRNA5,CNKSR3,DACT1,RTKN2,PJA1,RAB27B,SYNGR3,JAKMIP3,ARL4D,DOCK8,DZANK1,SSH3,GARS,FZD4,KCNH5,NPM3,PXYLP1,RAB38,TTC28,FGFR1,IRS2,GYPC,WWTR1,PLEKHG1,INPP4B,PAM,P4HA1,RCN3,TNFSF15,HOXB9,C2orf88,FARP1,ROBO2,EDA2R,IPO5,CREB5,P2RY1,PKN1,TSPAN17,NEO1,BHLHA15,MCF2L,GAS2L3,MORN2,MYO6,FES,ULBP1,BCL7A,LCA5,RAPGEF2,MCF2L2,ELOVL3,GAREM1,RACK1,SNTB1,HEG1,PTPRC,TRIB3,ID3,GNAO1,AKT3,XBP1,HK1,DOCK6,BTRC,FOXA1,TPT1,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,SYT14,NUP62CL,FSTL5,EOMES,TCAF2,KCNN2,KCNAB1,HPS1,MARVELD2,LIN7A,COL19A1,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,SLC3A2,PLPP2,PLEKHA1,TCERG1L,BATF,PLEKHB1,RUSC1-AS1,INHBC,MAP2,TECPR2,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,RASL11B,SETBP1,MLC1,IL18R1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,SEMA4F,IGF1R,GATA2,BCHE,BNIP3,FBXL2,FGFR4,PAK1,MID2,SLC27A2,RNF170,HOMER2,SPATA13,WDR25,PPFIA4,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,HEYL,TESC,SFN,MME,SIX2,PRKN,AVPI1,CFH,AKAP5,RBFOX2,ZNF83,RNF24,PCLO,CBLN1,CTNNA2,TBC1D19,FAM131B,RIDA,ZDHHC6,LHX6,ADGRL1,MYO3B,ZNF488,CTH,GLI1,TMEM67,EVL,TUBA1A,NOP53,FGF12,GSTO1,RARRES2,PAGE5,FRK,JAM3,ETNPPL,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ABI3,ITGA2,SEPT5,C8orf48,CNTN1,LPAR2,IL32,GRB14,RUSC2,APBB1,SELL,GABRG2,HBE1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,RASD2,EIF1,SH3PXD2B,PCK2,ESD,MOB1B,DLGAP1,MICAL2,PPP1R3D,NUAK2,LITAF,NPDC1,MAP10,TMEM237,FAT4,L3MBTL4,DLG2,PAX9,RPL4,THAP10,TBC1D4,CGN,MYCBP2,ACVR1,PPP4R4,PAGE1,ATP8A1,PPFIBP2,GATA3,ENAH,RAC3,NCS1,STK24,FAM168A,CFHR1,SLC22A18,GSTM3,SP140,PACSIN1,MAGEA6,RCAN3,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,DNAJC6,DEPTOR,DESI1,MEF2B,TNS1,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,NCKAP1L,CCBE1,CCDC181,RASGRF2,PLK2,SEMA3C,UNC5B,SPART,ZBED8,LZTS1,EFNB2,INPPL1,ALOX5AP,CELSR1,EHHADH,ZHX3,PTPRD,GABRB2,SCN8A,OPHN1,GTF2IRD1,TNFRSF10C,ISYNA1,ADSSL1,DYNC1I1,CHD5,MECOM,PIK3AP1,PDZD7,PRELID1,TSPAN12,MPDZ,SLC16A9,RIMS2,RNF152,EPB41L5,TBC1D8B,TCF24,COLGALT2,TTC30A,TTYH2,RABAC1,PLCB1,C4orf19,FAM162A,PKN3,PMEPA1,IQSEC2,AMPD1,EPHA3,TBKBP1,PCSK1N,AMOTL1,RASAL2,ELOVL4,RNF144A,OTX1,KCTD12,CHUK,NUDT12,TBC1D30,NELL2,ZNF827,TENT5A,NBEA,SCRN1,DAB2IP,MARCKS,SERPINH1,PDK1,TMEM43,PNMA6A,PRKCQ,TBC1D16,DCBLD2,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,ATG5,MAPK10,NR3C2,KCTD1,DENND5B,RPS20,WASF3,MXI1,CLBA1,ARL2,RGS7,GDPD5,NEDD4,HOPX,KDM7A,RGS17,SGK3,RALGAPA2,PRKG2,PHYKPL,FIG4,YBX3,SEPT3,GFI1,SPRY2,SMPDL3A,SYNPO2,ARAP2,HYKK,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,CEBPB,FGR,CLDN12,PCGF2,TUFT1,MYOM2,GRIN2D,B4GALT7,OCLN,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,TNFAIP8L2,JCHAIN,ABAT,CACNB4,RBM11,DNER,IKZF2,KREMEN1,QPRT,ARHGEF10L,RTN1,TUBB4A,LRRC6,GRHL1,AKAP7,POF1B,HRK,EPHB6,PTPRE,FANK1,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,ROR1,SERGEF,EML1,NCAM2,C8orf88,NCOA7,APBA2,BCL11B,FN1,SEC24D,JDP2,ELOVL7,ATP6V1E2,SATB1,ADGRG6,DDIT4,CA2,RPS11,EBF4,MORN4,NOS3,MSTN,SH2D2A,PARD3B,WWC1,DUSP9,PRDM1,LHPP,ADGRB3,FCHO2,HK2,RAI14,EGFL7,CXCR5,EML5,CELSR3,IL15,PLEKHA5,MORC4,LACC1,DOCK2,UBTD2,KCTD15,SETDB2,UNC13B,ZNF521,MAP7,STEAP3,MET,WWC2,POU2F2,ZNF460,HSPA2,DPP10,GCA,PHLDB2,FER,TES,SYNJ2BP,DOCK5,TTLL7,C1orf174,WARS,MSC,FAAP20,SOHLH2,DISP1,LIFR,PSPH,TNIK,CLGN,REL,LRP4,CUEDC2,RPL34,CHN2,EHD3,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,OGDHL,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,RERE,MAP1B,GPR37,TIFA,GCSAM,CT55,MPP7,NACC2,MAP2K6,PRCP,SLC7A5,KIF21A,GEM,MAP3K20,SNPH,STOM |
| 7.957e-05 | -9.44 | MODULE_99 | MSigDB lists | MODULE_99 | 348 | 57 | 17377 | 1707 |
WASF3,COL9A3,SV2B,UGT8,FN1,CFH,CLGN,GRB14,PRSS12,KIF5A,APBB1,RGS20,SSX1,ABAT,GABRR2,SLC1A3,CREB5,PRKCA,CACNB4,KCNC4,CTNNA2,CHRNA5,SLC30A4,BCHE,CFHR1,SLC22A18,GSTM3,NAP1L3,GULP1,ARL4D,NCAM1,ETV1,ZNF365,GFRA1,KCNB2,FZD1,LAMP3,FER,VNN2,BDNF,MEIS2,SOX21,ANK2,FHL2,PRDM1,GUCY1A2,LEPR,EML1,TRIM9,GPRC5B,PDLIM3,NCAM2,PTPRS,KLF5,NRP1,LIFR,AMPD1 |
| 7.997e-05 | -9.43 | GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_DN | 182 | 35 | 17377 | 1707 |
RGS16,FARP1,RNF144A,MYO1B,SELL,KCTD12,LCP2,SLC19A2,CHST10,FUT9,AFF2,BCL6,KCNS3,MAP7,TRPC1,ZNF460,CPE,RASGRP1,SMPDL3A,SNX7,DBN1,RHOQ,SLC39A8,PALLD,GUCY1A2,DKK1,PEMT,ATP7B,PTPRN2,SEMA3C,RPS12,ATG5,SHOX2,PCSK5,RRAGD |
| 7.997e-05 | -9.43 | GO_EPITHELIAL_CELL_DEVELOPMENT | MSigDB lists | GO_EPITHELIAL_CELL_DEVELOPMENT | 182 | 35 | 17377 | 1707 |
BCL11B,EXPH5,EPB41L5,TFCP2L1,ID1,ST14,RAPGEF2,NKX3-2,GATA3,COL18A1,TJP1,VIM,PRDM1,FNDC3A,PALLD,BMP6,ARHGEF26,FGFR1,HEG1,NKX6-1,MYADM,PDZD7,MARVELD2,XBP1,GSTM3,PTPRS,ACTA2,KLF5,PDE4D,BMP4,MET,MAGI2,SFN,SIX2,FOXA1 |
| 8.098e-05 | -9.42 | signal transducer activity, downstream of receptor | molecular function | GO:0005057 | 169 | 33 | 17224 | 1680 |
EPHA3,TYRO3,TNIK,ACVR1,BMPR2,NTRK3,MAPK4,EPHB1,DDR1,DOK5,TIAM2,STK24,IGF1R,FLRT3,ACVR2A,EPHB6,MET,SMAD6,SYK,PDGFRB,FGFR4,SMAD9,ACVR1C,ROR1,ACVR2B,FGFR1,SMAD3,ADRB1,MAP3K21,MAPK13,BMPR1A,MAPK10,MAP3K20 |
| 8.160e-05 | -9.41 | NAKAMURA_ADIPOGENESIS_EARLY_UP | MSigDB lists | NAKAMURA_ADIPOGENESIS_EARLY_UP | 57 | 16 | 17377 | 1707 |
WASF3,FAM198B,GAS1,DKK1,IRS2,TGFBR3,INSIG1,MYADM,MYC,PDE10A,ACVR2A,PDE4D,NPTXR,LIFR,CEBPD,SNAI2 |
| 8.186e-05 | -9.41 | regulation of dendrite development | biological process | GO:0050773 | 136 | 28 | 17256 | 1658 |
DBN1,TNIK,LZTS3,DNM3,ID1,PTPRD,DCC,RAPGEF2,SHANK2,VLDLR,LRRK2,PREX1,HECW2,SDK1,PPP1R9A,NEDD4,ARHGAP44,BAIAP2,ADGRB3,PLK2,RAP2A,KIAA0319,PTPRS,DAB2IP,PACSIN1,COBL,IL1RAP,MEF2C |
| 8.214e-05 | -9.41 | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN | 294 | 50 | 17377 | 1707 |
PLA2G4A,TFCP2L1,COL9A3,TRIM2,IL32,CKAP2,STXBP6,ITGA6,ACTL8,ADD2,IGF2BP2,GPSM2,PHGDH,MAGEA3,ST8SIA1,MAGEA6,ENO1,ZFP36L2,PERP,LRP12,CHRM3,GPR161,LAMP3,GLDC,PGBD5,NDUFA4L2,PRAME,PDK1,PRDM13,GSTM4,GALNT14,GPR19,PLEKHB1,SMPDL3B,WARS,ZIC1,DKK1,BCL11A,MAGEA12,PLOD2,TDO2,GBP1,KCNG1,WWTR1,SLC7A5,BMP1,KLF5,APBA2,PSPH,RRAGD |
| 8.261e-05 | -9.40 | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_NOT_VIA_AKT1_UP | 204 | 38 | 17377 | 1707 |
UST,BCL11B,TBKBP1,THOC5,FARP1,MORC4,SPATS2L,OVOL2,CHSY1,TPD52L1,PHLDA2,NCS1,GPRIN1,CNKSR3,KAZN,LHX6,STC2,REEP1,MPPED2,GAB2,PGBD5,CYP1B1,SUSD3,SH2D2A,SYBU,FHL2,DEPTOR,WWC1,FRK,TSKU,PDLIM3,WFS1,MFSD2A,XBP1,SLC7A5,HK2,SVIL,PTGES |
| 8.302e-05 | -9.40 | GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | 161 | 32 | 17377 | 1707 |
ANO10,SYNPO2,AVPI1,EIF4E3,MYO10,RAB6B,KCNH5,EXOC6B,RAPGEF4,PSD3,RASA3,TDRKH,ST6GALNAC3,DDR1,PLEKHB1,QPRT,IGF1R,RALGPS2,PRKCB,ABCA5,RND3,GNB4,RGS10,MARCH3,SERPINI1,SH3BGRL2,ZBTB20,DISP1,NEB,DIRC2,PRKACB,LPP |
| 8.410e-05 | -9.38 | lung-carcinoma | COSMIC cancer mutations | lung-carcinoma | 4311 | 486 | 17385 | 1698 |
ARHGAP26,MYCBP2,PAGE1,ACVR1,LANCL3,DUSP8,DNAJC3,PPFIBP2,GATA3,NPM1,ADAMTS6,CADM2,STAT5B,PRKCA,SNX9,RAC3,DACH2,HECTD2,SLC9A7,STK24,NOS1AP,PCDH7,TRPS1,SKI,BAG3,FBXO32,PMAIP1,SLC16A2,FAAH2,PPFIA2,RAP2A,RAB26,CHRDL1,PPP2R2B,NKX2-1,SMAD9,ACVR1C,KLHL4,TGFA,LRRK2,DNAJC6,LRMP,BNIP3L,DEPTOR,FEZ1,PRKAR2B,F12,ACVR2B,ZDHHC14,INTS6,SAV1,GNAI1,AHRR,HLF,PLK2,RASGRF2,ALDOA,ADRB1,BBC3,MAPK13,SERPINI1,ERCC5,INPP5F,DIRAS1,SPRY4,UNC5B,LPP,MEF2C,CARS,LATS2,GNG12,KLF8,INPPL1,ALOX5AP,PTPRD,ITGA6,ST6GAL1,MLF1,OPHN1,BTBD9,TNFRSF10C,GPSM2,DYNC1I1,BBS9,TNFRSF19,FOXG1,CHD5,GAS1,MECOM,CHN1,NAV1,BNIP1,RALGPS2,NOVA2,ADCK1,MYC,SRGAP1,PRKG1,TOX,MPDZ,LOXL4,ALPK1,SAMD13,RIMS2,RNF152,HMGCR,PTCH2,RPL26,PNP,TBC1D8B,PLEKHA8,STAT4,EFHC2,RAPGEF4,HIP1,SMARCD3,CDC42BPA,PLCB1,FAM162A,TMEM74,DHX32,BEX4,MMP15,PMEPA1,PKN3,ADAMTS3,HOXD13,SPRED3,FBXO27,IQSEC2,DHCR7,SMYD3,AMPD1,EPHA3,PLA2G4A,FRMPD3,PCSK1N,TMSB15A,RHOD,RNF144A,RGS20,IL13RA1,CHUK,GRK6,COLEC10,DDR1,COL14A1,ZFYVE9,CCDC120,RNF150,SPEG,DACT1,ALDOC,STARD4,FAM133A,NAP1L3,PDE4D,PJA1,ARL4D,SERPINH1,FAM155B,RAB27B,SNX10,GAB2,FZD1,TRDMT1,MYLK3,GAPDH,PDK1,ADM2,FZD4,PREX1,NLGN4X,WNT11,ATF3,PNMA6A,PRKCQ,PYGO1,RAB38,FGFR1,GJC1,IRS2,ZNF711,ARHGAP21,CXCL10,IKZF3,PRKCB,CCNA1,INPP4B,TNFSF15,GRB10,BMPR1A,MID1,RAB30,HACE1,MXI1,FARP1,EDA2R,FZD8,PLAG1,BIK,IPO5,ARL2,HERC5,GAS6,PKN1,RGS7,EPHB1,INPP1,TSPAN17,BEX2,NEDD4,RGS17,MCF2L,AFF2,PCBP4,GAS2L3,GHR,SGK3,SMAD6,SPRY2,ZFP36L2,FES,TMC7,BCL7A,VAV3,PXN,ALDH2,RAB6B,PTPN13,MPP1,MCF2L2,RAPGEF2,ZDHHC15,RASA3,AK4,SNTB1,GPLD1,CEBPB,PTPRC,ID3,TRIB3,FGR,AKT3,GNAO1,XBP1,NEK11,PIP5KL1,HK1,BMP4,TNFRSF17,FOXA1,BTRC,DDIT3,TRIM2,TRIM16,FGF13,PTPN21,ITPR2,SLC2A13,NUP62CL,NOVA1,IKZF2,KREMEN1,HMCN1,FSTL5,FKBP11,PLS3,RND2,ARHGEF10L,FKBP9,PPM1E,RPS6KA2,AKAP7,ITGB3,POF1B,HRK,CTTN,PTPRE,OR2W3,ETV1,ENO1,RAPGEF5,PDGFRB,PRKACB,RASGRP1,TNK2,ITGB7,SESN2,MARK1,COL4A3,YAP1,CR2,PLEKHA1,ROR1,TMEM47,COTL1,BATF,SGK2,RNF44,SESN1,SERGEF,PLEKHB1,TRIM9,DYRK1B,AK1,KCNMB4,HPSE,GNB4,ERN1,TNFRSF1A,NCOA7,PIK3C2B,TNFSF4,PPARGC1A,MLLT3,RRAGD,HS6ST3,BCL11B,PRKAA2,KCNV1,RGS16,RUNX2,RHOBTB1,JDP2,FBXO4,SATB1,DOK5,HSPA12B,DDIT4,RNF141,NUMBL,IGF1R,GATA2,LRP6,BNIP3,FBXL2,PTPRCAP,RNF148,SNX7,PAK1,FGFR4,MID2,RHOQ,SLITRK2,MSTN,SPATA13,DUSP9,PPFIA4,STRADB,MAFB,OBSCN,SDC3,PRDM1,KHDRBS2,MAPKAPK2,CSAG1,HK2,RAB31,PTPRN2,PLD1,NKX2-8,RNF122,FNBP1L,SFN,CXCR5,ID1,NEK10,CFH,DOCK1,AKAP5,PSTPIP2,PLEKHA5,ARHGAP22,HECW2,MORC4,BCL6B,RNF24,NTRK3,CANX,PPP1R9A,SLC22A17,TACC2,CDC14B,RPS6KL1,PPFIBP1,ZNF521,MYO3B,BCL6,ACVR2A,MET,POU2F2,HSPA2,GLI1,SUSD3,FER,PTPRU,PTPN6,ACO1,RNF125,VIM,CD40,FBXO36,FRK,PAGE5,BCL11A,SMAD3,MAGEA12,RANBP2,PTPRJ,BACH2,TRIM34,KPNA3,PTK7,EIF4EBP1,ITGA2,DUSP19,RGS10,MAOA,PTPRS,RNF130,SEPT5,LIFR,CTNND2,MAST1,HEY1,CNTN1,TNIK,DYRK3,ENO2,BMPR2,ARHGEF11,KLHL13,GRB14,REL,NLRP14,TNFSF13B,RASD1,IGF2BP2,COL4A5,USP30,PPP2R3A,FOXP2,CHN2,RASD2,PRKCD,SGK1,TRIM3,PCK2,RRAS2,TNFRSF11A,SYK,FKBP14,DUSP1,DLGAP1,RIN2,CARD6,PPP1R3D,USP2,RAB3B,FOXN3,CYTH3,SYBU,CRIP2,LITAF,NUAK2,PRRG1,MARS,AGAP2,ARHGAP32,CCNG1,MGMT,DKK1,ADAMTS17,SUGT1,EDA,RND3,MAP2K6,FMO4,SH3BGRL2,PAX9,GEM,RNF157,MMP16,IL9R,PTGES |
| 8.472e-05 | -9.38 | pleura-mesothelioma | COSMIC cancer mutations | pleura-mesothelioma | 4243 | 479 | 17385 | 1698 |
ARHGAP26,MYCBP2,PAGE1,ACVR1,LANCL3,DUSP8,DNAJC3,LDLR,PPFIBP2,GATA3,NPM1,STAT5B,ADAMTS6,CADM2,PRKCA,SNX9,RAC3,DACH2,SLC9A7,STK24,HECTD2,NOS1AP,SKI,PCDH7,TRPS1,BAG3,FBXO32,PMAIP1,SLC16A2,PPFIA2,FAAH2,RAP2A,RAB26,CHRDL1,PPP2R2B,NKX2-1,SMAD9,ACVR1C,TGFA,KLHL4,LRRK2,DNAJC6,LRMP,BNIP3L,DEPTOR,FEZ1,PRKAR2B,ACVR2B,SAV1,ZDHHC14,INTS6,GNAI1,AHRR,HLF,PLK2,RASGRF2,ALDOA,ADRB1,BBC3,MAPK13,ERCC5,INPP5F,DIRAS1,SERPINI1,SPRY4,UNC5B,LPP,MEF2C,CARS,KLF8,GNG12,LATS2,INPPL1,ALOX5AP,PTPRD,ITGA6,MLF1,ST6GAL1,OPHN1,BTBD9,GPSM2,TNFRSF10C,TNFRSF19,FOXG1,BBS9,CHD5,GAS1,MECOM,CHN1,NAV1,BNIP1,RALGPS2,NOVA2,ADCK1,MYC,PRKG1,SRGAP1,MPDZ,TOX,ALPK1,LOXL4,SAMD13,RIMS2,HMGCR,RNF152,PTCH2,RPL26,PNP,TBC1D8B,PLEKHA8,STAT4,RAPGEF4,EFHC2,SMARCD3,HIP1,CDC42BPA,PLCB1,FAM162A,TMEM74,DHX32,MMP15,BEX4,PMEPA1,ADAMTS3,PKN3,HOXD13,SPRED3,FBXO27,IQSEC2,DHCR7,SMYD3,AMPD1,PLA2G4A,FRMPD3,EPHA3,PCSK1N,RNF144A,TMSB15A,RHOD,RGS20,CHUK,IL13RA1,GRK6,COLEC10,DDR1,COL14A1,ZFYVE9,CCDC120,RNF150,SPEG,DACT1,ALDOC,STARD4,FAM133A,NAP1L3,PJA1,PDE4D,FAM155B,ARL4D,RAB27B,SERPINH1,SNX10,FZD1,GAB2,TRDMT1,MYLK3,GAPDH,PDK1,FZD4,PREX1,NLGN4X,WNT11,PNMA6A,PRKCQ,ATF3,RAB38,PYGO1,FGFR1,GJC1,ZNF711,IRS2,CXCL10,ARHGAP21,IKZF3,PRKCB,CCNA1,INPP4B,TNFSF15,GRB10,BMPR1A,MID1,RAB30,HACE1,FARP1,MXI1,EDA2R,FZD8,PLAG1,BIK,IPO5,ARL2,HERC5,GAS6,PKN1,EPHB1,RGS7,INPP1,TSPAN17,BEX2,NEDD4,RGS17,AFF2,MCF2L,PCBP4,GAS2L3,GHR,SGK3,SMAD6,SPRY2,ZFP36L2,FES,BCL7A,VAV3,ALDH2,PXN,RAB6B,MCF2L2,RAPGEF2,PTPN13,MPP1,ZDHHC15,AK4,RASA3,SNTB1,GPLD1,CEBPB,PTPRC,TRIB3,ID3,FGR,TERT,GNAO1,AKT3,XBP1,NEK11,PIP5KL1,BMP4,HK1,TNFRSF17,DDIT3,BTRC,FOXA1,TRIM2,FGF13,TRIM16,PTPN21,ITPR2,NUP62CL,IKZF2,NOVA1,KREMEN1,FKBP11,PLS3,ARHGEF10L,RND2,PPM1E,FKBP9,RPS6KA2,AKAP7,ITGB3,POF1B,HRK,CTTN,PTPRE,ENO1,ETV1,RAPGEF5,RASGRP1,PDGFRB,PRKACB,ITGB7,TNK2,SESN2,MARK1,COL4A3,YAP1,CR2,ROR1,PLEKHA1,TMEM47,COTL1,SGK2,BATF,RNF44,SESN1,SERGEF,PLEKHB1,DYRK1B,TRIM9,AK1,KCNMB4,HPSE,GNB4,ERN1,TNFRSF1A,NCOA7,PIK3C2B,TNFSF4,PPARGC1A,MLLT3,RRAGD,KCNV1,PRKAA2,BCL11B,RGS16,RUNX2,RHOBTB1,JDP2,FBXO4,SETBP1,SATB1,DOK5,HSPA12B,DDIT4,RNF141,NUMBL,IGF1R,GATA2,LRP6,BNIP3,RNF148,PTPRCAP,FBXL2,SNX7,PAK1,FGFR4,MID2,RHOQ,SLITRK2,MSTN,SPATA13,PPFIA4,SDC3,OBSCN,MAFB,DUSP9,STRADB,PRDM1,KHDRBS2,MAPKAPK2,CSAG1,HK2,RAB31,PTPRN2,PLD1,RNF122,NKX2-8,FNBP1L,SFN,CXCR5,NEK10,ID1,CFH,AKAP5,DOCK1,PLEKHA5,PSTPIP2,ARHGAP22,HECW2,MORC4,RNF24,BCL6B,NTRK3,PPP1R9A,SLC22A17,CDC14B,TACC2,PPFIBP1,RPS6KL1,MYO3B,ZNF521,BCL6,ACVR2A,MET,POU2F2,HSPA2,GLI1,SUSD3,FER,PTPRU,PTPN6,ACO1,RNF125,VIM,CD40,FBXO36,FRK,PAGE5,BCL11A,SMAD3,MAGEA12,RANBP2,PTPRJ,KPNA3,BACH2,TRIM34,PTK7,EIF4EBP1,ITGA2,RGS10,DUSP19,PTPRS,MAOA,RNF130,SEPT5,LIFR,CTNND2,CNTN1,MAST1,HEY1,TNIK,DYRK3,ENO2,BMPR2,KLHL13,ARHGEF11,GRB14,REL,NLRP14,TNFSF13B,IGF2BP2,COL4A5,RASD1,USP30,PPP2R3A,FOXP2,CHN2,PRKCD,RASD2,TRIM3,SGK1,PCK2,RRAS2,SYK,FKBP14,TNFRSF11A,DUSP1,DLGAP1,RIN2,PPP1R3D,CARD6,RAB3B,USP2,FOXN3,CRIP2,SYBU,CYTH3,LITAF,NUAK2,PRRG1,MARS,AGAP2,CCNG1,ARHGAP32,MGMT,DKK1,ADAMTS17,SUGT1,EDA,RND3,MAP2K6,FMO4,SH3BGRL2,PAX9,GEM,RNF157,IL9R,PTGES,MMP16 |
| 8.513e-05 | -9.37 | GOLDRATH_IMMUNE_MEMORY | MSigDB lists | GOLDRATH_IMMUNE_MEMORY | 63 | 17 | 17377 | 1707 |
ANTXR2,SORBS1,CHCHD7,PRSS12,RECK,PLEKHA5,CYP4V2,KCTD12,PDE8A,MCOLN2,BAG3,EOMES,SEMA4F,PCGF2,PROS1,FHIT,DOCK9 |
| 8.579e-05 | -9.36 | GO_MULTICELLULAR_ORGANISMAL_SIGNALING | MSigDB lists | GO_MULTICELLULAR_ORGANISMAL_SIGNALING | 120 | 26 | 17377 | 1707 |
TRPM4,SCN5A,KCNIP3,CACNG3,GRIK2,ANK2,SCN8A,PKP2,RYR2,KCND3,ATP1B1,DSP,CACNB4,JAM3,GJC1,KCNK15,KCNJ4,KCNMB4,SCN1B,CACNB2,DSG2,KCNMB3,SCN2A,SCN3A,CACNA2D1,ATP1A3 |
| 8.596e-05 | -9.36 | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_DN | 46 | 14 | 17377 | 1707 |
RAB3B,ENO2,PRKCB,PIK3AP1,TBC1D1,GPR160,STXBP6,ST6GAL1,LAPTM4B,ZNF215,PRKCA,RAPGEF5,DENND5B,BCL11A |
| 8.618e-05 | -9.36 | ENGELMANN_CANCER_PROGENITORS_DN | MSigDB lists | ENGELMANN_CANCER_PROGENITORS_DN | 69 | 18 | 17377 | 1707 |
NBL1,EVL,ID1,FN1,UGDH,SYBU,ADCY1,MAFB,SLX1B,CEBPA,GSN,VPS37D,SGK1,BMP4,OXTR,FBXO27,SEPT5,HSPA2 |
| 8.618e-05 | -9.36 | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | MSigDB lists | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | 69 | 18 | 17377 | 1707 |
PHLDB2,DNM3,RAB3B,LGR4,TGFA,C3orf52,IGF2BP2,SLC12A6,STEAP1,CENPV,HOMER3,ISG20,FAM131B,PLOD2,WWTR1,HK2,MET,PTGES |
| 8.621e-05 | -9.36 | CACTGCC,MIR-34A,MIR-34C,MIR-449 | MSigDB lists | CACTGCC,MIR-34A,MIR-34C,MIR-449 | 264 | 46 | 17377 | 1707 |
ARHGAP26,EML5,ACSL1,SIDT1,LGR4,XYLT1,OTX1,CREB5,GRK6,SLC2A13,MGAT5B,KIAA1217,FOXG1,SATB1,SLCO3A1,PPP2R3A,RGS17,LRRC55,SPEG,NUMBL,NAV1,MAP1A,SEMA4F,RALGPS2,BCL6,ZDHHC23,IQGAP3,NCEH1,MET,FIGN,SEPT3,MYRIP,ERGIC1,ANK2,NFE2L1,ELMOD1,GRID1,SATB2,PLCB1,GLCE,KLF12,ALDOA,MPP2,MLLT3,PKIA,CTNND2 |
| 8.751e-05 | -9.34 | basolateral plasma membrane | cellular component | GO:0016323 | 212 | 38 | 18223 | 1724 |
MYO1D,BMPR2,ST14,ITGA6,LDLR,TJP1,P2RY1,SLC12A6,MLC1,CTNNA2,EPCAM,KCNJ4,CA2,MARVELD2,MAP7,CNNM2,LIN7A,MET,SLCO4C1,TSHR,ATP2B1,CHRM3,SLC40A1,ABCC4,TGFA,ANK2,ATP1B1,DSP,LEPR,ENPP1,ATP7B,CDH17,HPGD,DLG2,DISP1,CDH2,SLC16A10,ATP2B4 |
| 8.759e-05 | -9.34 | GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_UP | MSigDB lists | GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_UP | 190 | 36 | 17377 | 1707 |
CXCR5,DOC2A,SEC24D,RNF144A,CCDC110,CYP4V2,ASS1,ABHD4,SNX9,GPR15,SEMA4F,IGF1R,ALDOC,PPFIBP1,LHX6,TMEM143,SERINC2,MYO3B,MARCH3,CERS4,NCAM1,SYNPO2,PTPN13,WWC1,CCNG1,SNTB1,ARRDC4,BATF,PYCR1,RPL12,SH3GL2,CSF1,ALDOA,INPP4B,KLF5,TESC |
| 8.794e-05 | -9.34 | Insulin secretion | KEGG pathways | hsa04911 | 85 | 21 | 7161 | 730 |
CREB3L2,TRPM4,ATF4,RAPGEF4,ADCY1,RYR2,CREB5,SNAP25,ATP1B1,PRKCA,PLCB1,PCLO,KCNMB4,KCNN2,PRKCB,KCNMB3,ADCY6,PRKACB,CHRM3,RIMS2,ATP1A3 |
| 8.972e-05 | -9.32 | P53_DN.V1_UP | MSigDB lists | P53_DN.V1_UP | 183 | 35 | 17377 | 1707 |
EXPH5,EFNB2,UGT8,IGFBP6,GRIK2,ASS1,GPSM2,INPP1,F3,EFEMP1,EPCAM,UNC13B,SLC16A2,SCRN1,MARCKS,RRAS2,CPE,SMAD6,SLIT2,SPRY2,CAND2,NKX2-1,LAMP3,MEIS2,CRIM1,FOXN3,FHL2,YAP1,DSP,C4BPB,DKK1,PTK7,ITGA2,KLF5,BMP4 |
| 8.972e-05 | -9.32 | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_DN | 183 | 35 | 17377 | 1707 |
DYRK3,FGF13,IL15,UBASH3B,ZCCHC24,EPS8,NSUN6,KIF5C,SFXN3,PRRG4,IL17D,CDC14B,RAP2A,GSTM3,PROS1,VWA5A,FAM78B,ZNF385A,CARD6,CSN2,DSTN,WLS,SDK1,NPC2,SNTB1,CAMK2N1,ENPP1,PTPRJ,AKT3,ADRB1,RAI14,MYOM2,BMPR1A,FBXO27,PANK3 |
| 9.025e-05 | -9.31 | skin-buttock-malignant_melanoma | COSMIC cancer mutations | skin-buttock-malignant_melanoma | 41 | 13 | 17385 | 1698 |
PTPRC,FER,PTPRJ,PTPRD,PTK7,PTPN13,PTPN21,PTPRS,PTPRN2,TNS1,EPHB1,MET,PTPRE |
| 9.099e-05 | -9.30 | Protein-protein interactions at synapses | REACTOME pathways | R-HSA-6794362 | 72 | 18 | 10287 | 971 |
DLGAP1,EPB41L5,PTPRD,SYT12,SHANK2,HOMER2,BEGAIN,NLGN4X,APBA1,NRXN1,HOMER3,EPB41L3,LIN7A,PTPRS,GRIN2D,DLG2,APBA2,STXBP1 |
| 9.145e-05 | -9.30 | DANG_REGULATED_BY_MYC_DN | MSigDB lists | DANG_REGULATED_BY_MYC_DN | 242 | 43 | 17377 | 1707 |
ACSL1,FN1,SCAMP1,MYO1B,GABRG2,CEBPA,SFXN3,CANX,GAS1,F3,PLS3,PMAIP1,MYC,NCAM1,ERRFI1,IL1RAP,PERP,RPS23,PDGFRB,FZD1,DUSP1,PDLIM7,BDNF,B3GALT1,FOXN3,LRMP,VLDLR,TMEM126A,NPC2,PYCR1,SNCA,ID3,CXCL10,WFS1,PAM,MCC,PLD1,RPS12,TPM1,CDH2,MAGI2,SFN,DDIT3 |
| 9.151e-05 | -9.30 | ATF2_UP.V1_DN | MSigDB lists | ATF2_UP.V1_DN | 176 | 34 | 17377 | 1707 |
PLA2G4A,MYO1D,PLSCR4,CFH,GALNT12,PKP2,KCTD12,SCD,FAM198B,GAS1,EFEMP1,FRY,ACVR2A,LIMCH1,SMAD6,IL1RAP,CTH,PNMA2,CYP1B1,MN1,NDUFA4L2,SLC39A8,AK4,SDC3,SLC25A28,PLS1,ROR1,GPR37,IRS2,PDLIM3,GPRC5B,ITGBL1,PELI2,SHOX2 |
| 9.167e-05 | -9.30 | cellular response to endogenous stimulus | biological process | GO:0071495 | 1136 | 147 | 17256 | 1658 |
CGN,ACVR1,ACSL1,ASS1,GATA3,STAT5B,ITPR2,SKI,FBXO32,TGFBR3,CHRDL1,TLR4,TSHR,SLIT2,PRKACB,PDGFRB,SESN2,GCNT2,ATF4,SMAD9,NR6A1,LRRK2,YAP1,PRKAR2B,ABCC2,FGF17,ACVR2B,SESN1,ENPP1,GNB4,MAPK13,OXTR,TNFSF4,PPARGC1A,MAGI2,RRAGD,MEF2C,PRKAA2,GNG12,LATS2,RUNX2,GABRB2,ATP6V1E2,DDIT4,EEF2,CA2,IGF1R,FLRT3,SREBF1,GRIP1,ADCY6,CHRM3,EPB41L5,PAK1,FGFR4,BDNF,RHOQ,MSTN,FHL2,RYR2,PDE8A,PLCB1,BAIAP2,CPEB1,SH3GL2,PMEPA1,HEYL,SH3BP4,RAB31,SMYD3,PRKN,ID1,SORBS1,RBFOX2,NTRK3,ZFYVE9,PLPP1,ASNS,ACVR2A,DAB2IP,PDE4D,SNAI2,FER,UROS,FGF12,ADCY1,FGFR1,SNCA,SMAD3,IRS2,EIF4EBP1,ITGA2,RGS10,HPGD,KLF5,BMPR1A,NR3C2,HEY1,CGB2,ROBO2,BMPR2,ESRP1,IPO5,LRP4,GABRG2,BMP6,NEDD4,NKX6-1,HMGCS1,PRKCD,GHR,GTF2F2,KLF9,ERRFI1,PCK2,SMAD6,ZFP36L2,ATP2B1,DUSP1,TRPM4,MSX1,GSTM2,PXN,KDM5B,HNF4G,NR4A1,ESRRG,RAPGEF2,FERMT2,GAREM1,MARS,TLR6,LEPR,GPLD1,GALNT3,CEBPB,TRIB3,FAT4,FBN1,XBP1,BMP4,TBC1D4,KIF1B,LARP1,ATP2B4,CACNA2D1,ATP1A3 |
| 9.177e-05 | -9.30 | lung-left_upper_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-left_upper_lobe-carcinoma-adenocarcinoma | 572 | 84 | 17385 | 1698 |
FAM171B,EXPH5,CACNG3,FAM13A,PCLO,FSTL5,SKI,TRPS1,COL22A1,SIPA1L2,TGFBR3,TM9SF2,DACT1,ZDHHC6,ALDH1L1,MPPED2,GSTM3,COL19A1,DAB2IP,CTH,VNN2,B3GALT1,CSN2,ADM2,JPH1,PREX1,METAP1D,ARHGAP21,PRKCB,MAP2,MAP9,LAMB1,BMP1,DNHD1,CTTNBP2,NR3C2,COBL,LIFR,CTNND2,LRFN5,IL32,PTPRD,LRP4,GABRG2,EPHB1,BCHE,FRAS1,GHR,RUNDC3B,PRKG1,SLC6A15,TBC1D9,NCAM1,GFI1,JAM2,ZNF518B,KIAA1211,CES3,SNX7,ZNF629,DLGAP1,CDH26,PCDH10,CACNA1E,ARID5B,EFHC2,KIAA1324L,RYR2,SDK1,ARHGAP32,GUCY1A2,ZFPM2,PLCB1,TMEM74,ZIC1,GPR37,CACHD1,FAT4,EMILIN2,CDH2,OSBPL6,CACNA2D1,DOCK9,ATP1A3 |
| 9.197e-05 | -9.29 | WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP | MSigDB lists | WATANABE_ULCERATIVE_COLITIS_WITH_CANCER_UP | 17 | 8 | 17377 | 1707 |
MN1,LCA5,ICA1,FBN1,LRP6,LIMCH1,PCSK5,TXNRD3 |
| 9.232e-05 | -9.29 | GO_PHOSPHOLIPID_BINDING | MSigDB lists | GO_PHOSPHOLIPID_BINDING | 342 | 56 | 17377 | 1707 |
PLA2G4A,DOC2A,ARHGAP26,PLEKHA5,SYT12,STXBP6,MYO1B,MCTP2,OPHN1,WDFY4,GAS6,ITPR2,SYT14,APBA1,NUP62CL,SNX9,PFN2,PCLO,ARHGAP44,ZFYVE9,SCIN,F3,TECPR1,ZFYVE28,MCF2L,SGK3,DAB2IP,MARCKS,SH3PXD2B,PACSIN1,CLVS2,SNX10,RASGRP1,FES,SNX7,GAB2,ARAP2,MARK1,PLEKHA8,MYO10,RAPGEF2,CYTH3,PREX1,HIP1,FERMT2,ARHGAP32,PLEKHA1,PLCB1,SNCA,FCHO2,PEMT,OSBPL5,PIK3C2B,PLD1,TC2N,ABCG1 |
| 9.284e-05 | -9.28 | regulation of stress fiber assembly | biological process | GO:0051492 | 77 | 19 | 17256 | 1658 |
PAK1,PHLDB2,EVL,PXN,GPR65,ASAP3,SORBS3,WNT11,PFN2,PPP1R9A,ARHGEF10L,SMAD3,PPM1E,ARHGAP28,SH3PXD2B,TPM1,NRP1,MET,TMEFF2 |
| 9.293e-05 | -9.28 | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP | 169 | 33 | 17377 | 1707 |
DMXL2,MYCBP2,TCP11L2,FLVCR2,SELL,ZNF215,SORBS3,CHN1,ATXN7L1,NELL2,KIAA0895,LRRN1,FAAH2,NBEA,ACVR2A,FHIT,TSHR,TMEM120B,FMNL2,ANKRD18B,SLC40A1,CD55,KLHL3,PTPN6,TCEA3,RASA3,ABCC2,COTL1,METAP1D,C11orf45,SFXN1,THBS4,SFMBT1 |
| 9.366e-05 | -9.28 | trans-synaptic signaling | biological process | GO:0099537 | 464 | 70 | 17256 | 1658 |
DOC2A,PRKN,GRIK2,AKAP5,SYT12,KIF5A,SYT14,NRXN1,CACNB4,NOVA1,RAC3,PCLO,PPP1R9A,CBLN1,CHRNA5,UNC13B,PPFIA2,LIN7A,LRRK2,FGF12,CHRNA6,SNCA,GJC1,TRIM9,HTR7,KCNMB4,TMOD2,SEPT5,APBA2,TC2N,MEF2C,SV2B,SLC6A9,GABRB2,GABRG2,SLC1A3,SLC12A6,GABRR2,APBA1,KCNC4,PCDHB14,SCN1B,CACNB2,RASD2,KCNMB3,LRP6,CADPS2,STXBP1,RIMS2,CHRM3,DLGAP1,BDNF,GPR176,KCNQ3,CACNA1E,GRID1,SLITRK5,PPFIA4,SNAP25,OR11H4,GPR19,DAGLA,GRIK4,PCDHB7,MPP2,PTPRN2,DLG2,GRIN2D,KIF1B,SNPH |
| 9.453e-05 | -9.27 | LIN7C (lin-7 homolog C, crumbs cell polarity complex component) | protein interactions | 55327 | 40 | 13 | 17029 | 1718 |
LATS2,KCNJ4,ABLIM1,MPP7,MPP2,YAP1,WWC1,MPDZ,APBA1,PXDC1,BAIAP2,ARHGEF26,PATJ |
| 9.554e-05 | -9.26 | RNGTGGGC_UNKNOWN | MSigDB lists | RNGTGGGC_UNKNOWN | 721 | 102 | 17377 | 1707 |
CREB3L2,BEGAIN,NPM1,CADM2,SEZ6L2,SLCO3A1,CD53,EPB41L3,PPM1E,SPEG,KCTD15,STARD4,FABP6,ACVR2A,HRK,EPHB6,PPP2R2B,PACSIN1,SYNGR3,PTPRE,TMEM56,KCNB2,PDGFRB,GLI1,ATL1,MEIS2,KCNIP3,GAPDH,RNF145,NR6A1,KLHL4,PTPN6,PANK1,FGF12,TCEAL3,SATB2,KCND3,FBXO36,NT5DC2,GYPC,KLF12,PRKCB,SH3RF1,ALDOA,B3GALT2,KLF5,DBP,SPRY4,COBL,KCNV1,COL9A3,MXI1,ANKRD13D,CCDC148,BMPR2,GRB14,OVOL2,EPHB1,APBA1,DYNC1I1,FOXG1,BMP6,RAB11FIP5,ATXN7L1,RGS17,MAP1A,LRRN1,FRY,RALGPS2,PCBP4,PDE10A,FLRT3,PRELID1,RUNDC3B,TSC22D1,FBXL2,NCAM1,GFI1,TSPAN9,AGL,FMNL2,CKAP4,GPR176,MICAL2,BDNF,NR4A1,VLDLR,OBSCN,UCHL3,TMEM74,RERE,CEBPB,ADAMTS3,C1orf21,MPP2,TMEM117,DLG2,PAX9,BMP4,PANK3,FOXA1,ATP2B4 |
| 9.793e-05 | -9.23 | V$GR_01 | MSigDB lists | V$GR_01 | 191 | 36 | 17377 | 1707 |
CCDC126,SORBS1,DNAJC3,ITGA6,OTX1,GATA3,ZIC2,IKZF2,NEDD4,FSTL5,TUBB4A,EPB41L3,SLC7A11,BHLHA15,TMEM86A,BCL6,ADCY6,FIGN,FES,BDNF,PXN,DSTN,KCNH5,JPH1,CALCRL,PRDM1,FGF17,MBNL2,RERE,MAP1B,NSD1,KLF5,DLX2,SEMA3A,CTNND2,FILIP1 |
| 9.793e-05 | -9.23 | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_DN | 191 | 36 | 17377 | 1707 |
CXCR5,CREB3L2,SCAMP1,SIDT1,PSTPIP2,TJP1,CA8,CBLN1,RND2,ASNS,IGF1R,PCBP4,DSG2,STC2,PROS1,CTTN,CERS4,SLC45A3,DUSP1,ERGIC1,DSTN,PTPN13,ARID5B,CENPV,GNAI1,BEX4,P4HA2,SLCO5A1,GRB10,SH3BGRL2,ZNF808,BMPR1A,GEM,SUSD4,PKIA,CTNND2 |
| 9.793e-05 | -9.23 | GO_EXCITATORY_SYNAPSE | MSigDB lists | GO_EXCITATORY_SYNAPSE | 191 | 36 | 17377 | 1707 |
DNM3,BMPR2,AKAP5,GRIK2,LRP4,EPS8,RGS20,CLSTN2,ADD2,PSD3,P2RY1,PCLO,PPP1R9A,NCS1,CTNNA2,EPB41L3,LIN7A,MPDZ,BNIP3,DLGAP1,DISC1,CAP2,SHANK2,HOMER2,DNAJC6,NLGN4X,ARHGAP32,BAIAP2,CPEB1,MAP1B,HOMER3,CAMK2N1,DLG2,MAGI2,LZTS1,CTNND2 |
| 9.793e-05 | -9.23 | GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 191 | 36 | 17377 | 1707 |
TNIK,SYT12,FZD8,RASL11B,NDRG2,SPATS2L,SLC12A6,ZNF219,SYDE2,CCNJ,SKI,SLC22A17,TACC2,MCF2L,PRKCD,TSC22D1,ADCY6,DYNC2H1,FAM84B,COG3,GFI1,SLC45A3,FES,PARP9,PTPRU,NR4A1,KLHL4,LRMP,ZDHHC15,DCBLD2,CAMK2N1,ATPAF2,KCNMB4,IKZF3,ACER2,TBC1D4 |
| 9.793e-05 | -9.23 | ATACTGT,MIR-144 | MSigDB lists | ATACTGT,MIR-144 | 191 | 36 | 17377 | 1707 |
PCDH18,RGS16,LGR4,RHOBTB1,PLAG1,GATA3,FOXG1,SEMA6A,NEDD4,FBXO32,SLC7A11,MARCKS,PDE4D,MYT1,ATP2B1,ANTXR2,RIN2,MSX1,GCNT2,MEIS2,PNRC1,PFKFB2,ESRRG,ANK2,PANK1,JPH1,ARID5B,CALCRL,ST6GALNAC3,FNDC3A,CACHD1,BACH2,IGIP,NCOA7,CDH2,LIFR |
| 9.883e-05 | -9.22 | SH3 | smart domains | SM00326 | 203 | 41 | 9493 | 1056 |
ARHGAP26,SORBS1,DOCK1,RUSC2,UBASH3B,EPS8,SORBS3,DOCK3,SNX9,DOCK2,CACNB2,MCF2L,SRGAP1,CTTN,SH3PXD2B,PACSIN1,NEB,VAV3,TNK2,SKAP2,MPP1,SHANK2,SPATA13,PACSIN3,ARHGAP32,DOCK5,FRK,SKAP1,BAIAP2,ARHGEF26,FGR,SH3GL2,MPP7,SH3RF1,ABI3,SH3BP4,MPP2,MAP3K21,DLG2,FNBP1L,NPHP1 |
| 9.890e-05 | -9.22 | CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | MSigDB lists | CHIARETTI_T_ALL_REFRACTORY_TO_THERAPY | 26 | 10 | 17377 | 1707 |
MXI1,DHCR24,BCL6,CR2,SELL,EPHB6,GFI1,MME,PSPH,FGFR1 |
| 9.907e-05 | -9.22 | Laminin_G | interpro domains | IPR001791 | 58 | 16 | 18492 | 1811 |
CELSR1,CELSR3,CNTNAP3,COL18A1,GAS6,NRXN1,COL14A1,COL27A1,NELL2,COL22A1,FAT4,THBS4,FAT1,COL19A1,PROS1,SLIT2 |
| 9.950e-05 | -9.22 | BURTON_ADIPOGENESIS_8 | MSigDB lists | BURTON_ADIPOGENESIS_8 | 82 | 20 | 17377 | 1707 |
B9D1,PDLIM7,BDNF,PHLDB2,GSTM2,TUBA1A,DSTN,TES,CD276,COL4A5,SKI,MAPKAPK2,SLC7A5,RAB31,ACTA2,NCAM1,PLTP,SMAD6,ZFP36L2,HMGCR |
| 1.000e-04 | -9.21 | GO_VASCULATURE_DEVELOPMENT | MSigDB lists | GO_VASCULATURE_DEVELOPMENT | 455 | 70 | 17377 | 1707 |
ACVR1,ID1,RECK,ARHGAP22,COL18A1,ADAMTS6,NRXN1,PRKCA,TYMP,ITGB3,DAB2IP,SLIT2,PDGFRB,CYP1B1,FZD4,ADM2,YAP1,WNT11,ACVR2B,JAM3,FGFR1,WARS,GJC1,HPSE,CCBE1,PTK7,HPGD,KLF5,SEMA3C,UNC5B,NRP1,MEF2C,HEY1,PCSK5,EFNB2,BMPR2,FN1,FZD8,SLC12A6,OVOL2,EPHB1,NEDD4,ACTA2,TSPAN12,DYNC2H1,ERRFI1,SMAD6,SYK,NOS3,B9D1,VEGFC,VAV3,SH2D2A,NR4A1,RAPGEF2,PRICKLE1,CALCRL,PRDM1,ZFPM2,HOXA1,LEPR,HEG1,GPLD1,PRCP,XBP1,EGFL7,BMP4,DHCR7,CDH2,DDIT3 |
| 1.000e-04 | -9.21 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | 343 | 56 | 17377 | 1707 |
MYCBP2,ID1,RHOBTB1,HEBP1,DNAJC3,ST6GAL1,ABHD13,PKP2,TJP1,NDFIP2,TSPAN17,IDI1,ZNF438,ZIC5,PRELID2,SCRN1,SGK1,BNIP3,MORN2,MARCKS,KLF9,TMEM37,VWA5A,ERRFI1,PLTP,GCNT2,PDK1,UROS,SKAP2,TBC1D8B,CLYBL,SPATA6,MGST3,ARID5B,TMTC4,BNIP3L,SGK2,FRK,CLN5,GPR19,HOXA1,ISG20,ENPP1,GSN,RNF217,GSTO2,RND3,GBP1,AKT3,XBP1,DSEL,PLD1,DBP,SHOX2,DCBLD1,DENND5B |
| 1.002e-04 | -9.21 | synaptic signaling | biological process | GO:0099536 | 465 | 70 | 17256 | 1658 |
DOC2A,PRKN,GRIK2,AKAP5,SYT12,KIF5A,SYT14,NRXN1,CACNB4,NOVA1,RAC3,PCLO,PPP1R9A,CBLN1,CHRNA5,UNC13B,PPFIA2,LIN7A,LRRK2,FGF12,CHRNA6,SNCA,GJC1,TRIM9,HTR7,KCNMB4,TMOD2,SEPT5,APBA2,TC2N,MEF2C,SV2B,SLC6A9,GABRB2,GABRG2,SLC1A3,SLC12A6,GABRR2,APBA1,KCNC4,PCDHB14,SCN1B,CACNB2,RASD2,KCNMB3,LRP6,CADPS2,STXBP1,RIMS2,CHRM3,DLGAP1,BDNF,GPR176,KCNQ3,CACNA1E,GRID1,SLITRK5,PPFIA4,SNAP25,OR11H4,GPR19,DAGLA,GRIK4,PCDHB7,MPP2,PTPRN2,DLG2,GRIN2D,KIF1B,SNPH |
| 1.004e-04 | -9.21 | V$MEF2_Q6_01 | MSigDB lists | V$MEF2_Q6_01 | 228 | 41 | 17377 | 1707 |
PRKAA2,TYRO3,ARHGAP26,INPPL1,FGF13,GRB14,RHOBTB1,MORC4,CTBP2,NEDD4,FOXP2,ZNF362,HS3ST5,GAN,TSC22D1,ADCY6,ETV1,RIMS2,SCN3A,DPP10,MID2,USP2,RNF145,TCEA3,FGF12,STRADB,SNAP25,ZFPM2,ASPH,MBNL2,RERE,KPNA3,PMEPA1,GNB4,ALDOA,DIRAS1,DLG2,PPARGC1A,FILIP1,CTNND2,CNTN1 |
| 1.005e-04 | -9.21 | GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_UP | 184 | 35 | 17377 | 1707 |
SEC24D,ATP8A1,ZNF25,CMTM8,RASL11B,SPATS2L,SLCO3A1,SLC19A2,RNF180,PPP1R26,CACNB2,ALDOC,PPFIBP1,ZDHHC23,OPN3,SH3PXD2B,FMNL2,CHRM3,IL17RD,PLEKHA8,LITAF,STRADB,RASA3,VIM,C3orf70,TCERG1L,CENPV,ARHGAP21,SH3RF1,FAT1,MATN2,FAM149A,SLC22A15,TTC39A,MLLT3 |
| 1.009e-04 | -9.20 | human chr13q32.3 | chromosome location | human chr13q32.3 | 27 | 9 | 26185 | 1967 |
TM9SF2,CLYBL,ZIC5,UBAC2,TMTC4,LINC01232,ZIC2,GGACT,DOCK9 |
| 1.013e-04 | -9.20 | skin-scalp-malignant_melanoma | COSMIC cancer mutations | skin-scalp-malignant_melanoma | 641 | 92 | 17385 | 1698 |
ARHGAP26,DMXL2,SORBS1,CACNG3,TTC39B,GRIK2,ATP8A1,RBFOX2,PTPN21,XYLT1,ARHGAP22,MSR1,HECW2,KIAA1217,COL14A1,DACH2,HMCN1,BAG3,COL22A1,RPS6KA2,TLR3,KMO,FAAH2,ALDH1L1,ATRNL1,PPP2R2B,WWC2,MET,PACSIN1,POU2F2,PTPRE,DNAH5,SLIT2,PDGFRB,FER,TNK2,ACVR1C,DCC,FZD4,CYB5R2,ALDH1L2,NFIA,TNS1,KCND3,TTLL7,TMEM132B,ARMC4,PTPRJ,SH3RF1,ITGBL1,NCKAP1L,PTK7,GBP1,PTPRS,SOHLH2,TMOD2,MRC2,BMPR2,PRSS16,PTPRD,CLGN,CYP2J2,GTF2IRD1,HERC5,HBE1,EPHB1,FAM174B,TNFRSF19,CA2,CACNB2,AGL,CHRM3,EPB41L5,VAV3,STAT4,PTPN13,KIAA1324L,PEX5L,PLCB1,KHDRBS2,SLC46A3,PTPRC,ADAMTS3,PKN3,RAI14,PTPRN2,MYOM2,PLD1,XKR4,MMP16,ATP1A3,TPT1 |
| 1.015e-04 | -9.20 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-mast_cell_neoplasm | 252 | 44 | 17385 | 1698 |
MYO1D,FN1,RHOBTB1,RIMKLA,HECW2,PSD3,NPM1,GALNT13,CHSY1,EPHB1,DNER,HMCN1,COL22A1,TGFBR3,CA2,ZFYVE28,BACE2,KAZN,FAM107B,ATRNL1,CADPS2,SLC2A12,TMEM132E,FAM155A,TSHR,MICAL2,PFKFB2,NFIA,ACO1,GRID1,KCND3,TCERG1L,SESN1,ILDR2,MGMT,NRG3,PLEKHH2,POPDC3,ENTPD7,PTPRN2,SERPINI1,GRB10,NRP1,TANC2 |
| 1.015e-04 | -9.20 | mast_cell_neoplasm | COSMIC cancer mutations | mast_cell_neoplasm | 252 | 44 | 17385 | 1698 |
MYO1D,FN1,RHOBTB1,RIMKLA,HECW2,PSD3,NPM1,GALNT13,CHSY1,EPHB1,DNER,HMCN1,COL22A1,TGFBR3,CA2,ZFYVE28,BACE2,KAZN,FAM107B,ATRNL1,CADPS2,SLC2A12,TMEM132E,FAM155A,TSHR,MICAL2,PFKFB2,NFIA,ACO1,GRID1,KCND3,TCERG1L,SESN1,ILDR2,MGMT,NRG3,PLEKHH2,POPDC3,ENTPD7,PTPRN2,SERPINI1,GRB10,NRP1,TANC2 |
| 1.025e-04 | -9.19 | CORRE_MULTIPLE_MYELOMA_DN | MSigDB lists | CORRE_MULTIPLE_MYELOMA_DN | 58 | 16 | 17377 | 1707 |
TCEA3,SETBP1,NLGN4X,SLC1A3,TNFRSF19,GAS1,INSIG1,CNKSR3,LIN7A,CADPS2,HS3ST3B1,KIF21A,ZFP36L2,MME,CEBPD,FZD1 |
| 1.028e-04 | -9.18 | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_UP | MSigDB lists | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_UP | 177 | 34 | 17377 | 1707 |
DOC2A,C2orf88,STOX2,PLSCR4,CACNG3,GLIPR1L1,RBFOX2,BACE1,MAPK4,COLEC10,NHP2,COL14A1,EYA4,TIAM2,SCIN,GATA2,FAM189A1,WWC2,ARL4D,SPRY2,LRP3,PGBD5,DBN1,DLGAP1,EML6,FERMT2,SATB2,UCHL3,C1orf174,BEX4,ZNF704,DLX2,CTTNBP2,PCSK5 |
| 1.028e-04 | -9.18 | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_DN | 177 | 34 | 17377 | 1707 |
FBXO4,MYO1B,DDR1,TBC1D30,SLC9A7,CYP51A1,HMGCS1,SEMA4F,KMO,BACE2,PDE10A,FRAS1,TSPAN13,SYK,GATM,GAB2,BCL7A,GPM6A,USP2,FZD4,CR2,ARHGAP32,ATP11A,TAF4B,TLR6,TTC28,BCL11A,ENTPD1,HEYL,SPRY4,MID1,RAB30,SFN,MEF2C |
| 1.028e-04 | -9.18 | GCAAAAA,MIR-129 | MSigDB lists | GCAAAAA,MIR-129 | 177 | 34 | 17377 | 1707 |
EFNB2,STOX2,BMPR2,SCN8A,ITGA6,SLC25A27,PSD3,STAT5B,EPHB1,DOCK3,SP8,PCDH7,GALNT1,BCL6,DAB2IP,TOX,FIGN,JAKMIP3,ETV1,ZNF385A,MEIS2,ESRRG,TMTC4,PRDM1,BACH2,IGIP,PRKCB,PMEPA1,SFMBT1,DLX2,XKR4,NR3C2,ATP2B4,KCTD1 |
| 1.032e-04 | -9.18 | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) | protein interactions | 7529 | 381 | 62 | 17029 | 1718 |
CGN,MYCBP2,SORBS1,FN1,RASAL2,TBC1D1,PLEKHA5,SLK,PKP2,RGS7,TPD52L1,RADIL,DDIT4,GPR15,EPB41L3,BAG3,SIPA1L2,ABLIM1,NAV1,IGF1R,RALGPS2,KIAA1671,DACT1,MYC,PPFIBP1,PRKCD,ACTA2,GRIP1,ERRFI1,TESPA1,ZFP36L2,PHLDB2,FER,MARK1,LCA5,PFKFB2,PTPN13,LRRK2,SPATA13,YAP1,WWC1,TTC28,BAIAP2,SNCA,IRS2,KCNK15,KIAA0355,SH3RF1,MAP3K21,RAI14,INPP5F,GEM,TANC2,TBC1D4,MAP3K20,KIF1B,SFN,FOXA1,LARP1,FRMD5,BTRC,MAST1 |
| 1.041e-04 | -9.17 | ANTXR2 (anthrax toxin receptor 2) | protein interactions | 118429 | 13 | 7 | 17029 | 1718 |
LRP6,COL4A5,ANKRD13D,COL4A3,LGR4,COL4A4,LAMB1 |
| 1.042e-04 | -9.17 | GO_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 108 | 24 | 17377 | 1707 |
PDLIM7,TRPM4,ACVR1,ID1,RUNX2,BMPR2,ZHX3,CD276,CEBPA,ACVR2B,BMP6,FGFR1,SKI,CEBPB,SMAD3,ID3,ACVR2A,HGF,BMPR1A,BMP4,SNAI2,FZD1,MEF2C,GLI1 |
| 1.042e-04 | -9.17 | V$COMP1_01 | MSigDB lists | V$COMP1_01 | 108 | 24 | 17377 | 1707 |
MEIS2,CACNG3,PDE1B,DHCR24,COL4A5,PRDM8,CREB5,SLC1A3,SPINK5,MBNL2,FKBP11,ZIC1,HTR7,FOXP2,KCTD15,GNB4,MPPED2,MPP2,SLC2A12,DLG2,SPRY4,SERPINH1,NCAM1,CTNND2 |
| 1.044e-04 | -9.17 | heart development | biological process | GO:0007507 | 499 | 74 | 17256 | 1658 |
ACVR1,ID1,GATA3,PKP2,ADAMTS6,NTRK3,TGFBR3,SETDB2,EOMES,KCNAB1,TBC1D32,CPE,PDGFRB,SNAI2,FZD1,MYLK3,TMEM65,ANK2,FGF12,MEF2B,YAP1,WNT11,CBY1,ACVR2B,SAV1,DSP,GJC1,SMAD3,ARMC4,POPDC3,PTK7,APELA,PAM,SEMA3C,OXTR,BMPR1A,ATG5,NRP1,TPM1,HEY1,PCSK5,MEF2C,SCN5A,BMPR2,BVES,OVOL2,ADGRG6,FHOD3,GATA2,FLRT3,DSG2,LRP6,DYNC2H1,SH3PXD2B,SMAD6,MICAL2,MSX1,DCHS1,FHL2,PRICKLE1,NSD2,SMARCD3,RYR2,CALCRL,PRDM1,ZFPM2,HEG1,ID3,FAT4,FBN1,HEYL,MYOM2,BMP4,SHOX2 |
| 1.044e-04 | -9.17 | positive regulation of cellular component biogenesis | biological process | GO:0044089 | 499 | 74 | 17256 | 1658 |
DNM3,ID1,GPR65,JCHAIN,NTRK3,NRXN1,PRKCA,SNX9,RAC3,CBLN1,SCIN,ARHGEF10L,PPM1E,UNC13B,PMAIP1,ADGRL1,HRK,CTTN,MET,TLR4,IL1RAP,FER,PHLDB2,GPM6A,EVL,MYLK3,WNT11,AMIGO1,WARS,SMAD3,GSN,PTPRJ,WIPF3,NCKAP1L,ERCC5,OXTR,TPM1,NRP1,COBL,TENM1,PTPRD,BIK,EPS8,CLSTN2,ARL2,SORBS3,SLX1B,GPSM2,EPHB1,PFN2,SPIRE1,ADGRB2,LRRN1,FLRT3,GTF2F2,SH3PXD2B,FES,PAK1,EPB41L5,BDNF,SYNPO2,RHOQ,PXN,SLITRK2,SLITRK5,RACK1,TLR6,BAIAP2,RIPOR2,ADGRB3,MPP7,CDH17,FNBP1L,NPHP1 |
| 1.049e-04 | -9.16 | CUB | pfam domains | PF00431 | 47 | 14 | 17054 | 1666 |
ST14,BMP1,ATRNL1,C1R,PCOLCE2,SEZ6L2,NRP1,LRP3,ADGRG6,KREMEN1,LRP12,DCBLD1,TLL2,DCBLD2 |
| 1.049e-04 | -9.16 | ROZANOV_MMP14_TARGETS_SUBSET | MSigDB lists | ROZANOV_MMP14_TARGETS_SUBSET | 31 | 11 | 17377 | 1707 |
EFEMP1,COL6A2,FN1,PLOD2,GJB2,EMILIN2,MATN2,LAMB1,COL18A1,CHSY1,SERPINH1 |
| 1.049e-04 | -9.16 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_DN | 31 | 11 | 17377 | 1707 |
VEGFC,ALDH1L2,OPN3,TSPAN12,MYOM2,TMEM47,STEAP1,CTH,GLCE,RRAGD,CD53 |
| 1.053e-04 | -9.16 | epithelial cell development | biological process | GO:0002064 | 181 | 34 | 17256 | 1658 |
BCL11B,EXPH5,TFCP2L1,ID1,ST14,COL18A1,TJP1,BMP6,NKX6-1,PDZD7,MARVELD2,ACTA2,POF1B,GSTM3,PDE4D,MET,EPB41L5,NKX3-2,RAPGEF2,VIM,PRDM1,FNDC3A,PALLD,FGFR1,ARHGEF26,HEG1,MYADM,XBP1,PTPRS,KLF5,BMP4,MAGI2,SFN,FOXA1 |
| 1.060e-04 | -9.15 | regulation of protein modification process | biological process | GO:0031399 | 1804 | 219 | 17256 | 1658 |
PHACTR3,ACSL1,PPP4R4,ACVR1,FGF13,DUSP8,GRIK2,DNAJC3,GATA3,NPM1,NDRG2,CEBPA,PRKCA,SNX9,STK24,NOS1AP,SKI,GSDME,PPM1E,PPP1R26,TGFBR3,ZFYVE28,RAP2A,ITGB3,PPP2R2B,EPHB6,RCAN3,TLR4,SLIT2,PRKACB,RASGRP1,PDGFRB,TNK2,SESN2,GCNT2,TGFA,LRRK2,DEPTOR,PRKAR2B,ACVR2B,ROR1,INHBC,ENPP1,GPRC5B,SH3RF1,NCKAP1L,ERN1,NCOA7,TNFRSF1A,INPP5F,DIRAS1,SPRY4,NRP1,PPARGC1A,MAGI2,CACUL1,PRKAA2,TYRO3,LATS2,FN1,FBXO4,SLK,JDP2,UBASH3B,SORBS3,TNFRSF10C,PFN2,TNFRSF19,MECOM,DDIT4,RNF180,FRY,IGF1R,GATA2,MYC,FLRT3,C1QL4,SREBF1,LRP6,INAVA,ADCY6,HMGCR,BOD1,PAK1,FGFR4,MSTN,VLDLR,DUSP9,WWC1,STRADB,PDE8A,ARRDC4,PLCB1,HERPUD1,BEX4,MAPKAPK2,PMEPA1,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,TESC,SFN,EPHA3,PRKN,ID1,NEK10,AVPI1,CELSR3,IL15,NTRK3,LCP2,PIBF1,TNKS1BP1,DDR1,PPP1R9A,TLR3,CDC14B,CNKSR3,DACT1,BCL6,ACVR2A,DAB2IP,PDE4D,MET,HSPA2,IGFBP3,ALG10B,FZD1,FER,FZD4,NOP53,PTPN6,ADCY1,PREX1,ATF3,WNT11,RARRES2,SYNJ2BP,CD40,MAGI3,FGFR1,SNCA,WARS,CAMK2N1,CXCL10,NRG3,PTPRJ,GBP1,APELA,WFS1,WWTR1,MAP3K21,DUSP19,TNFSF15,HGF,BMPR1A,ATG5,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,IPO5,LRP4,HERC5,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,BMP6,PPP2R3A,PRKCD,RASD2,GHR,AFAP1L2,ERRFI1,IQGAP3,GFI1,SMAD6,TNFRSF11A,SYK,SPRY2,PARP9,DUSP1,MOB1B,VEGFC,RAPGEF2,PRICKLE1,GAREM1,PHACTR2,CCNG1,RACK1,TLR6,DKK1,GPR37,PTPRC,TRIB3,NSD1,FGR,DOCK7,MYADM,ACER2,MAP2K6,LRRK1,BMP4,MAP3K20,ATP2B4,PKIA |
| 1.062e-04 | -9.15 | CUB | prosite domains | PS01180 | 49 | 15 | 12060 | 1278 |
ADGRB3,ST14,BMP1,ATRNL1,C1R,PCOLCE2,SEZ6L2,NRP1,LRP3,ADGRG6,KREMEN1,LRP12,DCBLD1,DCBLD2,TLL2 |
| 1.070e-04 | -9.14 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN | 149 | 30 | 17377 | 1707 |
DPP10,KLF8,SCN5A,SH2D2A,MPP1,LSM11,BNIP3L,ACO1,RNF125,TMEM200C,ATP1B1,SLC12A6,FRK,HOXA1,EML1,DDIT4,TXNRD3,CD53,ANKRD42,ZNF362,SCN1B,P4HA2,ALDOC,AFAP1L2,CAB39L,KIAA1549,SMYD3,SIX2,FZD1,GAB2 |
| 1.081e-04 | -9.13 | TGANTCA_V$AP1_C | MSigDB lists | TGANTCA_V$AP1_C | 1062 | 141 | 17377 | 1707 |
PLBD2,PDE1B,FGF13,ASS1,NDRG2,ADAMTS6,STAT5B,ABHD4,NCS1,SLC9A7,F3,TUBB4A,RTN1,SEC16B,SLC22A18,SERINC2,PPP2R2B,TLN2,ENO1,PDGFRB,ATL1,GPM6A,ATF4,MARK1,DSTN,RNF44,TSKU,GNAI1,TRIM9,MAP2,SH3RF1,ALDOA,DIRAS1,PPARGC1A,FRMD5,LPP,MEF2C,SEMA6B,SCN5A,LGALS3,ZHX3,SEC24D,RASL11B,GALNT13,FAM81A,HPCAL4,PRRG4,MECOM,SMTN,BNIP3,LOXL4,GFRA1,IGSF3,BDNF,RHOQ,MSTN,MGST3,PACSIN3,AIG1,PRDM1,SNAP25,PKN3,C1orf21,SFN,MME,CXCR5,NUDT10,PCSK1N,SCAMP1,ELOVL4,XYLT1,FAM198B,NRXN1,PRR7,DDR1,ZFYVE9,ZNF362,ZNF827,SCRN1,PDE4D,RAB27B,SNX10,PERP,GAB2,GAPDH,RNF145,PFKFB2,PTPRU,TMEM43,PRDM13,FGF12,ATP1B1,ASPH,TTLL7,ISG20,GABARAPL1,POPDC3,ITGA2,ABI3,KLF5,HS3ST3B1,MAPK10,COBL,RAB30,RPS20,IGFBP6,ENO2,KLHL13,CREB5,PKN1,SEL1L3,PHLDA2,COL27A1,TTC1,MAP1A,MCF2L,STC2,SGK3,GTF2F2,SGK1,KLF9,GFI1,PCSK6,RIN2,USP2,ARAP2,ESRRG,AGPAT4,CTTNBP2NL,ARHGAP32,ILDR2,RERE,NSD1,AKT3,SVIL,SLCO5A1,SLC1A5,SHOX2,DDIT3,FOXA1,SNPH |
| 1.089e-04 | -9.13 | GO_TAXIS | MSigDB lists | GO_TAXIS | 440 | 68 | 17377 | 1707 |
CXCR5,CELSR3,KIF5A,PLXNA2,GATA3,ENAH,NRXN1,DOCK2,SEMA6A,TYMP,ITGB3,PDE4D,MET,ETV1,SLIT2,SEMA6C,PDGFRB,NKX2-1,FER,EVL,DCC,PREX1,FEZ1,PRKCQ,RARRES2,ATOH1,CXCL10,NRG3,PTPRJ,NCKAP1L,SEMA3C,HGF,UNC5B,NRP1,HOXB9,EFNB2,BCL11B,SEMA6B,LGALS3,ROBO2,CMTM8,OPHN1,KIF5C,GAS6,EPHB1,NEO1,CHN1,SEMA4F,CNTN4,SCN1B,FLRT3,PRKCD,NCAM1,TNFRSF11A,SYK,FES,DPYSL5,VEGFC,TRPM4,VAV3,BDNF,UNC5C,NR4A1,EFNA3,MATN2,BMP4,PLD1,SEMA3A |
| 1.093e-04 | -9.12 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP | 192 | 36 | 17377 | 1707 |
PLA2G4A,HEBP1,ST6GAL1,EPS8,MCOLN3,IGF2BP2,CD7,SNX9,SLCO3A1,IL18R1,FHOD3,CA2,TSC22D1,GSTM3,DAB2IP,B4GALT6,PAK1,SH3BP2,GCNT2,SKAP2,VIM,SHISA2,ST6GALNAC3,BCL11A,BEX4,DOCK7,ICA1,MYADM,TRIM34,PRCP,RAI14,RAB31,GRB10,LRRK1,GEM,MEF2C |
| 1.093e-04 | -9.12 | GSE7852_LN_VS_FAT_TCONV_DN | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_DN | 192 | 36 | 17377 | 1707 |
ARHGAP26,INPPL1,FARP1,SEC24D,COBLL1,KCTD12,BEX2,NEDD4,HOPX,MECOM,PLS3,EFEMP1,RAB11FIP5,BAG3,MARVELD2,TSC22D1,TMED9,KLF9,ZFP36L2,ANTXR2,ATF4,PNP,NR4A1,AGPAT4,GPSM1,HIP1,ATF3,SLC25A28,PRDM1,SNCA,ENTPD1,CAMK2N1,ARHGAP21,MYADM,LRRK1,ATP2B4 |
| 1.112e-04 | -9.10 | TGCTTTG,MIR-330 | MSigDB lists | TGCTTTG,MIR-330 | 313 | 52 | 17377 | 1707 |
BCL11B,EFNB2,ACVR1,RUNX2,BMPR2,OTOGL,ZCCHC24,YPEL2,PLXNA2,PRDM8,TJP1,ABHD4,FOXG1,TRPS1,PPM1E,PRTFDC1,TGFBR3,DLX6,LHX6,RAP2A,FAM107B,PRKG1,TRIM3,TOX,NCEH1,NPTXR,ATP2B1,IGSF3,DPP10,ANTXR2,GPM6A,FOXN3,SOX21,CYTH3,JPH1,SYBU,EFNA3,GRID1,FRK,MBNL2,PLCB1,FGFR1,IQCH,SH3GL2,RND3,PRKCB,GNAO1,SHOX2,KIF1B,CRISPLD1,BTRC,MEF2C |
| 1.113e-04 | -9.10 | positive regulation of cell development | biological process | GO:0010720 | 500 | 74 | 17256 | 1658 |
EPHA3,PRKN,NBL1,DOCK1,PLXNA2,NTRK3,RAC3,PPP1R9A,SEMA6A,RND2,BCL6,DAB2IP,PACSIN1,ZNF488,ZNF365,SLIT2,IL1RAP,FZD1,MYLK3,FZD4,SHANK2,PREX1,FEZ1,AMIGO1,ATOH1,DOCK5,FGFR1,GPRC5B,PTK7,HGF,SEMA3C,SERPINI1,DLX2,NRP1,MAGI2,COBL,CNTN1,MEF2C,FN1,ROBO2,BMPR2,PTPRD,PLAG1,APBB1,GDPD5,FOXG1,BMP6,NKX6-1,NUMBL,GATA2,SCN1B,GRIP1,FIG4,FES,RIMS2,VEGFC,PAK1,DISC1,BDNF,RAPGEF2,VLDLR,SMARCD3,BAIAP2,DKK1,NEGR1,MAP1B,MYADM,CSF1,HEYL,BMP4,SHOX2,SEMA3A,FOXA1,SHTN1 |
| 1.114e-04 | -9.10 | positive regulation of signal transduction | biological process | GO:0009967 | 1600 | 197 | 17256 | 1658 |
ACVR1,LGR4,TRIM16,LMCD1,GATA3,CTBP2,ABAT,PRKCA,STK24,NOS1AP,SKI,F3,GSDME,TGFBR3,PMAIP1,ITGB3,HRK,EPHB6,TLR4,RASGRP1,PDGFRB,CYP1B1,GCNT2,ATF4,SKAP2,WLS,TGFA,LRRK2,YAP1,ACVR2B,ROR1,FGF17,INHBC,GSN,GPRC5B,HPSE,CCBE1,PLK2,ERN1,ADRB1,TNFRSF1A,BBC3,TMOD2,DIRAS1,NRP1,UNC5B,MLLT3,RRAGD,TYRO3,SORBS3,CHSY1,TNFRSF10C,TNFRSF19,CHD5,IL18R1,MYORG,CHN1,IGF1R,PIK3AP1,LRP6,INAVA,BNIP3,ZNF385A,RIMS2,HMGCR,PAK1,FGFR4,RPL26,MID2,BDNF,ATP5IF1,DISC1,MSTN,SH2D2A,DUSP9,WWC1,HIP1,PDE8A,PLCB1,FAM162A,BAIAP2,MAPKAPK2,ADAMTS3,PELI2,CSF1,INHBE,CDH2,SEMA3A,SFN,EPHA3,PRKN,BTC,SORBS1,NEK10,AVPI1,IL15,GPR65,NTRK3,CHUK,NRXN1,DDR1,PIBF1,TLR3,UNC13B,DACT1,SHF,ACVR2A,DAB2IP,MET,GLI1,CTH,IGFBP3,INTU,FZD4,PTPN6,SHANK2,WNT11,GSTO1,ATF3,CD40,FGFR1,IRS2,SMAD3,CXCL10,PTPRJ,PRKCB,APELA,MAP3K21,DUSP19,TNFSF15,HGF,GRB10,BMPR1A,DISP1,MAPK10,MID1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,GRB14,FZD8,REL,EPS8,BIK,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,TSPAN17,BMP6,NEDD4,NEO1,CHN2,PRKCD,RASD2,GHR,AFAP1L2,DYNC2H1,IQGAP3,GFI1,TNFRSF11A,TESPA1,SYK,SPRY2,PARP9,TRPM4,VAV3,SH3BP2,GSTM2,MSX1,RAPGEF2,LITAF,GAREM1,RACK1,SKAP1,TLR6,DKK1,GPR37,PTPRC,FGR,EDA,NACC2,TERT,MPP7,MAP2K6,AKT3,XBP1,LRRK1,BMP4,SHOX2,MAP3K20,DDIT3,FOXA1 |
| 1.115e-04 | -9.10 | BCAT_GDS748_UP | MSigDB lists | BCAT_GDS748_UP | 47 | 14 | 17377 | 1707 |
CEBPB,SLC39A14,BAG3,DDAH1,SLC3A2,CA2,C3orf52,PKP2,KCTD12,WNT11,PDE4D,COTL1,DYNC1I1,PHLDA2 |
| 1.125e-04 | -9.09 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP | 185 | 35 | 17377 | 1707 |
GXYLT2,LGALS3,MCTP2,KCTD12,NRN1,GABRR2,DACH2,QPRT,RTN1,OTUD1,IGF1R,ZFYVE28,KMO,AFF2,GHR,MARCH3,LRP6,PACSIN1,RAB27B,SMAD6,PFKFB4,IL17RD,EVL,SMAD9,RAPGEF2,TTLL7,FRK,ATP10D,GPLD1,CXCL10,PRCP,SH3BGRL2,HOXB9,SNPH,PCSK5 |
| 1.125e-04 | -9.09 | AAANWWTGC_UNKNOWN | MSigDB lists | AAANWWTGC_UNKNOWN | 185 | 35 | 17377 | 1707 |
MPZL3,CACNG3,FN1,ZHX3,GATA3,NTRK3,FOXP2,ATXN7L1,ZNF827,LRRN1,PPFIA2,BCL6,LOXL4,SEMA6C,PDGFRB,DUSP1,DPYSL5,SESN2,TBC1D8B,FOXN3,DSTN,ANK2,SATB2,ATP1B1,GPC6,BCL11A,EBF1,KLF12,DLG2,DSEL,PPARGC1A,MID1,ATP2B4,DDIT3,MEF2C |
| 1.139e-04 | -9.08 | GO_CEREBRAL_CORTEX_DEVELOPMENT | MSigDB lists | GO_CEREBRAL_CORTEX_DEVELOPMENT | 102 | 23 | 17377 | 1707 |
GNG12,DISC1,FGF13,VLDLR,EFHC1,ATOH1,PLCB1,FGFR1,FOXP2,FAT4,EOMES,TACC2,LHX6,LAMB1,PTPRS,LRP6,DAB2IP,NRP1,SEMA3A,CDH2,SLIT2,POU3F3,NKX2-1 |
| 1.148e-04 | -9.07 | DLG4 (discs large MAGUK scaffold protein 4) | protein interactions | 1742 | 119 | 26 | 17029 | 1718 |
DLGAP1,EFNB2,PRKN,PCDH10,SCN5A,GRIK2,AKAP5,FZD4,SHANK2,BEGAIN,NLGN4X,IL13RA1,ARHGAP32,GUCY1A2,PRKCA,KCNJ4,MAP1A,SEMA4F,ADGRL1,ADRB1,LIN7A,GRIN2D,DLG2,KIF1B,ATP2B4,FZD1 |
| 1.153e-04 | -9.07 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | 178 | 34 | 17377 | 1707 |
UST,RHOBTB1,FBXO4,UGDH,MYO1B,MCTP2,SETBP1,COLEC10,DDR1,NIPSNAP3B,TIAM2,SLC9A7,HMGCS1,SEMA4F,FRAS1,PDE10A,EHD3,ITGB3,MARCH3,TSPAN13,MOXD1,RRAS2,GATM,SYK,VAV3,USP2,GPM6A,CR2,MAP1B,BCL11A,ENTPD1,GALNT3,MEF2C,ZNF235 |
| 1.157e-04 | -9.06 | filopodium | cellular component | GO:0030175 | 99 | 22 | 18223 | 1724 |
GPM6A,FARP1,INPPL1,FGF13,MYO10,ITGA6,APBB1,MYO1B,SPATA13,ENAH,EPHB1,PPP1R9A,TIAM2,BAIAP2,RIPOR2,MAP2,FAT1,ITGB3,ACTA2,NPTXR,MORN4,SHTN1 |
| 1.165e-04 | -9.06 | squamous_cell_carcinoma | COSMIC cancer mutations | squamous_cell_carcinoma | 17068 | 1685 | 17385 | 1698 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,CNTNAP3,RECK,MCOLN3,TUBE1,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,VASH2,C12orf77,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,LAPTM4B,HOXD13,CDH2,DOCK9,MTG1,TFCP2L1,ABHD13,ADD2,GRK6,SLC19A2,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,NECAB1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,LAMB1,FAM149A,LRRC27,RAB30,CGB2,CCDC148,ANKRD13B,WDR17,CKAP2,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,LRRN1,PCBP4,GHR,ZFP36L2,C15orf41,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,TM9SF2,CPVL,AADAT,SEC16B,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,TMEM132E,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,FAM201A,NFE2L1,TMEM200C,CR2,TTC22,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,FHAD1,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,NEUROG2,TC2N,CACUL1,HS6ST3,RRAGD,LONRF1,KCNV1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,SLITRK5,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,TMEM65,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,BMPR2,KLHL13,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,DUSP1,LRRIQ1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,NDUFB8,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,ACVR1C,WISP3,KLHL3,FAM84A,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,LRFN5,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,RALGPS2,SLC7A11,ADCK1,NOVA2,MYC,C1QL4,PRKG1,SREBF1,GRIP1,CPXM2,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,CECR2,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,SNCA,ISG20,ZNF711,IKZF3,POPDC3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,PRSS35,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,PHLDA2,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,SMAD6,B4GALT6,TMC7,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,ZDHHC15,UCHL3,GPR137C,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,ADPRHL1,EPCAM,LGI2,SIPA1L2,PPM1E,ABI3BP,ANKFN1,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,TMEM47,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,FAM114A2,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,FAM81A,SPINK5,PCDHB14,RNF141,ZNF354A,EEF2,SLC30A4,LIMCH1,RNF148,LRP3,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,HBG2,PODXL2,RHOQ,SLITRK2,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,TMEM154,PLAGL1,CSAG1,KIAA0355,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,XKR4,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,PPFIBP1,KAZN,C12orf60,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,OVOL2,FAM174B,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,CCDC122,MARCH3,AFAP1L2,IPCEF1,RBMS2,PNMA2,CARD6,USP2,HNF4G,CRIM1,SYBU,ASAP3,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,UACA,RPS12,RNF157,IL9R,NPHP1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,FAM102B,STAT5B,CADM2,CHAC1,DOCK3,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,FBXO32,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,TSHR,KLHL29,NKX2-1,RWDD2A,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,MSRB3,F12,MFSD6,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,KIAA1671,BACE2,FAM189A1,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,C4A,FAM131C,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,RNF150,EPB41L3,CHRNA5,GPRIN1,KMO,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,RNF145,FZD4,KCNH5,NKX3-2,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCK,IQCH,GYPC,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,C1orf226,NKAIN2,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,FAM227A,SYT12,FHDC1,ASS1,LILRB1,NRN1,SYT14,NUP62CL,NOVA1,FSTL5,ANKRD42,FKBP9,KCNN2,KCNAB1,EOMES,HPS1,MARVELD2,COL19A1,LIN7A,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,INHBC,MAP2,P4HA2,GNB4,TECPR2,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,KIAA0895,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,SAMD11,BNIP3,SLCO4C1,PTPRCAP,FBXL2,PAK1,CHSY3,FGFR4,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,TMTC4,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,NAP1L5,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,FAM198B,LPIN3,SEZ6L2,KBTBD11,CBLN1,PCLO,CYP26A1,TBC1D19,FAM131B,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,SCN2A,FAM78B,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,THSD4,FGF12,GSTO1,RARRES2,FBXO36,PAGE5,FRK,JAM3,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,KIAA1211,DLGAP1,PPP1R3D,MICAL2,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,DEXI,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,THAP10,TBC1D4,FILIP1,C2orf27A,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,TTC39B,SIDT1,TCP11L2,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,CHRDL1,GSTM3,ATRNL1,BEND4,SP140,MAGEA6,PACSIN1,VWA5A,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,MEF2B,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,TANC2,UNC5B,LZTS1,EFNB2,INPPL1,EHHADH,CELSR1,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,WDFY4,SLC1A3,ADSSL1,DYNC1I1,CHD5,NIPSNAP3B,RPL13A,PRRG4,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,PDZD7,VWDE,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,SAMD13,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,KIAA1324L,TTC30A,TTYH2,CCDC85A,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,XKR9,VPS37D,PMEPA1,PKN3,ISM1,IQSEC2,ANKRD20A5P,AMPD1,ACSM3,EPHA3,FRMPD3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,TMEM53,ZNF827,STARD4,SCRN1,NBEA,DAB2IP,NAP1L3,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,LINC00896,ZNF396,HTR7,PRKCB,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,ANO10,WASF3,ANKRD13D,MXI1,GLIPR1L1,ATP9A,CCNJL,ARL2,GPR180,GABRR2,RGS7,GDPD5,NEDD4,HOPX,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,SLC6A15,FIG4,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,NUTM2A,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,ANKRD18A,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,CEP85L,FKBP11,QPRT,RTN1,ARHGEF10L,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,PCOLCE2,PTPRE,FANK1,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,EML1,TMEM132B,AK1,ITGBL1,NCAM2,NCOA7,APBA2,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,DDIT4,OTUD1,CA2,RPS11,EBF4,FAM107B,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,ANKRD20A2,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,HK2,RAI14,EGFL7,DIRC2,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,SUSD3,DPP10,FER,PHLDB2,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,MEI1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,C3orf70,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,MPP7,NACC2,PRCP,MAP2K6,THSD7B,SLC7A5,KIAA0513,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH |
| 1.169e-04 | -9.05 | GO_REGULATION_OF_SYSTEM_PROCESS | MSigDB lists | GO_REGULATION_OF_SYSTEM_PROCESS | 490 | 74 | 17377 | 1707 |
MTG1,CACNG3,LMCD1,PKP2,ITPR2,ABAT,PRKCA,CACNB4,NOS1AP,FBXO32,TRPC1,CTTN,PDE4D,KCNB2,KCNIP3,TMEM65,ANK2,GSTO1,PRKCQ,KCND3,ATP1B1,DOCK5,DSP,ASPH,FGFR1,GJC1,KCNMB4,ITGA2,ADRB1,HGF,OXTR,TPM1,PPARGC1A,WASF3,SCN5A,C1QTNF3,BMPR2,BVES,CYP2J2,GTF2IRD1,P2RY1,GAS6,BMP6,NEDD4,HOPX,RAB11FIP5,KCNJ4,SCN1B,CACNB2,DSG2,PRKG1,SREBF1,ADCY6,SGK1,FIG4,ERRFI1,ATP2B1,CHRM3,HMGCR,NOS3,TRPM4,GSTM2,KDM5B,MSTN,RYR2,CALCRL,KCNK15,GNAO1,GRIN2D,TRPC3,SEMA3A,CACNA2D1,ATP2B4,ATP1A3 |
| 1.182e-04 | -9.04 | endometrium-carcinoma-serous_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-serous_carcinoma | 1466 | 185 | 17385 | 1698 |
MYCBP2,PPP4R4,FGF13,TRIM16,GRIK2,CNTNAP3,RECK,ANKRD18A,NUP62CL,HMCN1,TRPS1,LRRC6,KCNN2,ABI3BP,PPFIA2,ANKFN1,COL19A1,POF1B,TMEM132E,ETV1,NEB,PRKACB,GLDC,PGBD5,GDAP1,MARK1,DCDC1,SMAD9,ACVR1C,SPOCD1,KLHL3,LRRK2,ABCC2,CRYBG3,EML1,P4HA2,B3GALT2,ERCC5,PIK3C2B,TMOD2,TANC2,UNC5B,DNHD1,SPOCK3,EFNB2,LONRF1,KCNV1,SV2B,STXBP5L,SEC24D,CYP2J2,ZCCHC24,RIMKLA,CHADL,WDFY4,FHOD3,RNF141,SYCP2,RALGPS2,SEMA4F,FRY,ABCA5,FAM189A1,PDE10A,SRGAP1,MPDZ,LIMCH1,ALPK1,AGL,COL9A2,IL17RD,PCDH10,SLITRK2,STAT4,RYR2,SMARCD3,OBSCN,AIG1,CDC42BPA,B4GALNT3,CLN5,TMEM74,SPATA7,CACHD1,PLEKHH2,ADAMTS3,CECR2,FAT1,MATN2,PTPRN2,SLFN5,AMPD1,ACSM3,DOCK9,EPHA3,SORBS1,ST14,GALNT6,RBFOX2,LRRCC1,HECW2,MORC4,ADD2,NRXN1,COL14A1,SEMA6A,PCLO,ZFYVE9,TXNRD3,ZSCAN5A,EPB41L3,COL22A1,KCTD15,PPFIBP1,ACVR2A,PDE4D,DNAH5,MYT1,ATP6AP1L,SNAI2,DOCK8,KCNB2,TRDMT1,PFKFB2,TRAM1L1,NLGN4X,TCEAL3,TTLL7,DOCK5,TTC28,METAP1D,ENTPD1,ARMC4,KPNA3,GPR160,INPP4B,RGS10,PAM,P4HA1,ALG11,GRB10,HGF,PLD5,MID1,C8orf48,CTNND2,CNTN1,TNIK,CCDC148,FARP1,PLAG1,APBB1,NEDD4,PPP2R3A,SLC35F1,FOXP2,CHN2,MGAT1,GPR155,RALGAPA2,MARCH3,RRAS2,SMPDL3A,MED12L,ARAP2,AGPAT4,MCF2L2,FERMT2,FNDC3A,ZIC1,MAP1B,HEG1,GALNT3,NSD1,FAT4,TERT,FBN1,AKT3,OSBPL5,SVIL,BMP4,KIF21A,KIF1B,CRISPLD1,FILIP1 |
| 1.190e-04 | -9.04 | cell-cell signaling involved in cardiac conduction | biological process | GO:0086019 | 27 | 10 | 17256 | 1658 |
TRPM4,SCN5A,KCNN2,SCN1B,CACNB2,ANK2,RYR2,PKP2,CACNA2D1,GJC1 |
| 1.191e-04 | -9.04 | NELSON_RESPONSE_TO_ANDROGEN_UP | MSigDB lists | NELSON_RESPONSE_TO_ANDROGEN_UP | 83 | 20 | 17377 | 1707 |
ABCC4,SEC24D,UGDH,HOMER2,PTPN21,DHCR24,ARID5B,SCD,SNAP25,HMGCS1,IDI1,UNC13B,CDC14B,PMEPA1,C1orf21,TSC22D1,INPP4B,SGK1,HPGD,LIFR |
| 1.195e-04 | -9.03 | GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | 164 | 32 | 17377 | 1707 |
PLSCR4,LGALS3,TSPAN15,BVES,OLAH,KIF5C,LRRC49,TDRKH,SATB1,STK24,CHN1,ABLIM1,ASNS,SCRN1,PPP2R2B,ALPK1,RNF148,ETV1,PTPN13,ATOX1,VLDLR,C3orf52,FERMT2,TTC22,HLF,ICA1,TIFA,SH3GL2,MYADM,SRD5A3,SH3BGRL2,MAPK10 |
| 1.208e-04 | -9.02 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP | 157 | 31 | 17377 | 1707 |
SUSD3,CARS,SERINC5,PDK1,EBPL,CHCHD7,ACVR1C,SFXN4,CYP2J2,PLAG1,APBB1,DCHS1,YPEL2,CR2,OBSCN,FAM117B,ARHGAP32,AMIGO1,SLC12A6,TAF4B,PRKCA,KIAA1958,TECPR1,IGF1R,ALDOC,SREBF1,RGS10,LAPTM4B,SLC16A10,LAMP3,ZNF629 |
| 1.211e-04 | -9.02 | GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 1341 | 172 | 17377 | 1707 |
ACVR1,LGR4,TRIM16,VAMP8,GATA3,CEBPA,STAT5B,ABAT,PRKCA,NOS1AP,F3,RND2,ITGB3,CTTN,PACSIN1,TLR4,SLIT2,RASGRP1,PDGFRB,CYP1B1,GCNT2,ATF4,YAP1,FEZ1,ACVR2B,F12,GPRC5B,HPSE,NCKAP1L,CCBE1,ADRB1,BMP1,ZBTB20,MAPK13,OXTR,NRP1,TPM1,PPARGC1A,TNFSF4,VASH2,MAGI2,MEF2C,EFNB2,RUNX2,LGALS3,FN1,ZHX3,PTPRD,IL18R1,NUMBL,CA2,GATA2,FLRT3,MYC,LRP6,RIMS2,CHRM3,NOS3,HMGCR,PTCH2,EPB41L5,BDNF,DISC1,PNP,SLITRK2,VLDLR,RYR2,SMARCD3,SLITRK5,PLS1,PRDM1,PLCB1,CPEB1,BAIAP2,NEGR1,MAPKAPK2,CSF1,HEYL,SEMA3A,TRPC3,TESC,SFN,EPHA3,PLA2G4A,NBL1,AMOTL1,IL15,AKAP5,NTRK3,NRXN1,PIBF1,PPP1R9A,CBLN1,SEMA6A,SCIN,TLR3,BCL6,ACVR2A,DAB2IP,MARCKS,PDE4D,MET,ZNF488,CTH,GLI1,PHLDB2,ADM2,WNT11,GSTO1,PRKCQ,ATOH1,AMIGO1,CD40,FGFR1,BCL11A,SMAD3,PRKCB,PTK7,WWTR1,ITGA2,HGF,BMPR1A,ATG5,COBL,CNTN1,WASF3,C1QTNF3,ROBO2,BMPR2,CD276,PLAG1,APBB1,CLSTN2,P2RY1,GAS6,OVOL2,EPHB1,GDPD5,BMP6,NKX6-1,FOXP2,LRRN1,SCN1B,GHR,TFAP2A,SGK1,AFAP1L2,FIG4,IQGAP3,TNFRSF11A,SYK,FES,TRPM4,PDLIM7,VEGFC,USP2,KDM5B,RAPGEF2,ZFPM2,TLR6,MAP1B,GPLD1,HEG1,CEBPB,DDAH1,FGR,TERT,XBP1,BMP4,SHOX2,FOXA1,DDIT3 |
| 1.212e-04 | -9.02 | ZHANG_TLX_TARGETS_36HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_36HR_UP | 215 | 39 | 17377 | 1707 |
LATS2,PLBD2,SORBS1,ACSL1,DUSP8,FBXO4,ABHD4,SLCO3A1,SLC19A2,DDIT4,SLC7A11,SCN1B,TSC22D1,OPN3,VWA5A,STXBP1,PTPRE,ZFP36L2,GAB2,QSOX1,PXN,SESN2,RNF145,MYO10,NR4A1,SDC3,TNS1,CCNG1,KCND3,GABARAPL1,AK1,GSN,NACC2,CSF1,SPRY4,MAPK10,KIF1B,DDIT3,STOM |
| 1.213e-04 | -9.02 | positive regulation of synapse assembly | biological process | GO:0051965 | 66 | 17 | 17256 | 1658 |
BDNF,SLITRK2,PTPRD,CLSTN2,SLITRK5,NTRK3,AMIGO1,EPHB1,NRXN1,CBLN1,ADGRB2,ADGRB3,LRRN1,FLRT3,ADGRL1,OXTR,IL1RAP |
| 1.214e-04 | -9.02 | GSE21927_EL4_VS_MCA203_TUMOR_MONOCYTES_UP | MSigDB lists | GSE21927_EL4_VS_MCA203_TUMOR_MONOCYTES_UP | 150 | 30 | 17377 | 1707 |
RGS16,NBL1,ATF4,ADAL,PDE1B,MSTN,CYP2J2,PTPN6,CLSTN2,NDRG2,BCL6B,KCTD12,CHAC1,CACNB4,TBC1D2,FSD1,GSN,TYMP,PPP1R26,PCDHB7,RNF217,ENPP6,HRK,PDE4D,PPARGC1A,SHOX2,SLIT2,PTGES,FOXA1,PDGFRB |
| 1.214e-04 | -9.02 | V$MEIS1AHOXA9_01 | MSigDB lists | V$MEIS1AHOXA9_01 | 109 | 24 | 17377 | 1707 |
GCNT2,KLHL4,ESRRG,CACNA1E,CREB5,SATB1,NOVA1,NAP1L5,TCF7L1,ZNF362,FBXO32,CHN2,UNC13B,KLF12,FLRT3,SAMD11,ZIC5,TFAP2A,HRK,BEND4,FIGN,NRP1,GATM,KIF1B |
| 1.222e-04 | -9.01 | bone-tibia-other-chondroblastoma | COSMIC cancer mutations | bone-tibia-other-chondroblastoma | 103 | 23 | 17385 | 1698 |
INTU,VAV3,GPM6A,ACSL1,SLC36A1,CNTNAP3,REL,NKAIN2,CLSTN2,ST6GALNAC3,PALLD,CA8,PLCB1,NAALADL2,SMPDL3B,FSTL5,GYPC,IGF1R,LRRIQ3,NCOA7,LAPTM4B,COL19A1,CTNND2 |
| 1.223e-04 | -9.01 | regulation of synapse structure or activity | biological process | GO:0050803 | 175 | 33 | 17256 | 1658 |
DNM3,ROBO2,PTPRD,LRP4,CLSTN2,NTRK3,EPHB1,NRXN1,PPP1R9A,CBLN1,CTNNA2,NEDD4,ARHGAP44,ADGRB2,LRRN1,FLRT3,ADGRL1,DAB2IP,IL1RAP,BDNF,LZTS3,SLITRK2,SYBU,LRRK2,SLITRK5,AMIGO1,BAIAP2,DKK1,SNCA,ADGRB3,OXTR,CDH2,MEF2C |
| 1.224e-04 | -9.01 | V$CEBPA_01 | MSigDB lists | V$CEBPA_01 | 230 | 41 | 17377 | 1707 |
PLA2G4A,NEK10,MXI1,RASAL2,TNFSF13B,OTX1,ZIC2,COLEC10,CA8,SP8,FOXP2,CACNB2,LHX6,BCL6,TSC22D1,SLC6A15,PROS1,PDE4D,FIGN,SMAD6,FES,NDUFA4L2,BDNF,SSH3,CD55,RHOQ,MEIS2,CRIM1,JPH1,PRDM1,ARRDC4,TBC1D16,ID3,TCF7L1,GYPC,MAP2K6,MAOA,ZBTB20,HOXB9,FRMD5,RAB30 |
| 1.232e-04 | -9.00 | Regulation of insulin secretion | REACTOME pathways | R-HSA-422356 | 80 | 19 | 10287 | 971 |
GNG12,AKAP5,CACNA1E,RAPGEF4,ARL2,PRKAR2B,ITPR2,SNAP25,PRKCA,PLCB1,GNAI1,GNB4,CACNB2,KCNS3,ADCY6,MARCKS,STXBP1,CHRM3,PRKACB |
| 1.240e-04 | -9.00 | negative regulation of protein phosphorylation | biological process | GO:0001933 | 435 | 66 | 17256 | 1658 |
PRKN,DUSP8,DNAJC3,NDRG2,NPM1,CEBPA,NTRK3,PIBF1,PPM1E,ZFYVE28,CNKSR3,DACT1,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,PTPN6,LRRK2,PREX1,DEPTOR,ATF3,PRKAR2B,SYNJ2BP,SNCA,WARS,CAMK2N1,ENPP1,PTPRJ,GBP1,WWTR1,DUSP19,HGF,INPP5F,SPRY4,PPARGC1A,LATS2,UBASH3B,IPO5,PKN1,DDIT4,MECOM,IGF1R,FLRT3,MYC,C1QL4,PRKCD,LRP6,ERRFI1,SMAD6,SPRY2,DUSP1,HMGCR,DUSP9,RACK1,DKK1,PTPRC,TRIB3,MYADM,PMEPA1,LRRK1,BMP4,TESC,SMYD3,PKIA,SFN |
| 1.257e-04 | -8.98 | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN | MSigDB lists | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN | 186 | 35 | 17377 | 1707 |
ALOX5AP,FLVCR2,PDE1B,PLEKHA5,DENND3,EPCAM,BNIP1,TGFBR3,CNKSR3,FAAH2,PCBP4,PRKCD,ACVR2A,TOX,ST8SIA1,SLCO4C1,MICAL2,CRIM1,PTPN13,CYTH3,PHACTR2,COTL1,PRDM1,BATF,SAV1,GALNT3,GNAO1,C1orf21,ERN1,ABI3,BMPR1A,IL9R,KIF1B,ATP2B4,ATP1A3 |
| 1.257e-04 | -8.98 | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | 186 | 35 | 17377 | 1707 |
EXPH5,TNIK,RASAL2,TBC1D1,LRRCC1,CYP4V2,COBLL1,MECOM,RAB11FIP5,FRY,AKAP7,TSC22D1,CERS4,CAND2,ANTXR2,AGPAT4,PARD3B,VLDLR,NFIA,PREX1,TTC28,SESN1,ATP10D,ZIC1,HLF,ZNF266,TMEM154,BACH2,IGIP,LAPTM4B,HGF,SPRED3,FNBP1L,PHC1,ABCG1 |
| 1.268e-04 | -8.97 | MODULE_37 | MSigDB lists | MODULE_37 | 426 | 66 | 17377 | 1707 |
ACVR1,AASS,BEGAIN,GATA3,NDRG2,BAG3,TGFBR3,PDE4D,SP140L,GCA,SOX21,KLHL4,AMIGO1,SAV1,SMAD3,SPNS1,ENPP1,CCBE1,ABI3,ALDOA,NCOA7,PLEKHG1,TNFSF4,RRAGD,PCSK5,MOCOS,SV2B,SLC25A27,PRDM8,SCD,HBE1,ISYNA1,IL18R1,SYCP2,RALGPS2,DHRS12,IPCEF1,TBC1D9,FAR2,LRP3,MED12L,VEGFC,QSOX1,SH3BP2,KDM5B,TBC1D8B,GSTM4,SDC3,OBSCN,WDR25,AGAP2,PRDM1,LHPP,CCNG1,RERE,GALNT3,DEXI,PCDHB7,CSF1,WDR19,DYNC2LI1,NXPH4,HOXD13,LARP1,PKIA,SLC43A1 |
| 1.276e-04 | -8.97 | Extracellular matrix organization | REACTOME pathways | R-HSA-1474244 | 296 | 48 | 10287 | 971 |
COL9A3,FN1,ITGA6,LRP4,LAMC3,COL18A1,COL4A5,NRXN1,BCAN,PRKCA,DDR1,COL14A1,COL27A1,EFEMP1,COL22A1,COL25A1,ITGB3,COL19A1,PHYKPL,LOXL4,PCOLCE2,SERPINH1,NCAM1,JAM2,COL9A2,ITGB7,COL6A2,COL4A3,COL4A4,CAPN5,COLGALT2,SDC3,JAM3,MMP15,ADAMTS3,FBN1,PLOD2,P4HA2,CTSV,ITGA2,LAMB1,BMP1,P4HA1,PTPRS,BMP4,SPOCK3,MMP16,TLL2 |
| 1.283e-04 | -8.96 | V$FOXO4_01 | MSigDB lists | V$FOXO4_01 | 223 | 40 | 17377 | 1707 |
BCL11B,MXI1,C1QTNF3,CHCHD7,PLAG1,BIK,RASD1,TJP1,CADM2,NTRK3,SLC12A6,COLEC10,EPHB1,FOXG1,IKZF2,ZFYVE9,NEO1,DDIT4,MECOM,TRPS1,FOXP2,ATXN7L1,SLC10A7,ZNF521,TSPAN13,PDE4D,ETV1,BDNF,MEIS2,VLDLR,SLITRK5,SLC25A28,SATB2,PRDM1,SKAP1,NAP1L5,MSC,KLF12,TNFSF4,SHOX2 |
| 1.285e-04 | -8.96 | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | MSigDB lists | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_UP | 71 | 18 | 17377 | 1707 |
EFNB2,PNP,IGFBP6,HERC5,HERC6,ISG20,CXCL10,HPSE,BCHE,GBP1,MAGEA3,BMP4,MAGEA6,SEMA3A,PRR16,TLR4,ZFP36L2,SLIT2 |
| 1.285e-04 | -8.96 | GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | 71 | 18 | 17377 | 1707 |
GSTM2,ANK2,RYR2,GSTO1,ATP1B1,SGK2,ASPH,NOS1AP,AKAP7,CACNB2,PRKCD,SGK3,SGK1,BMP4,SYNGR3,HSPA2,TESC,CACNA2D1 |
| 1.290e-04 | -8.96 | GO_REGIONALIZATION | MSigDB lists | GO_REGIONALIZATION | 307 | 51 | 17377 | 1707 |
NBL1,CELSR1,BMPR2,LRP4,OTX1,RGS20,PLXNA2,OVOL2,CHSY1,PGAP1,SP8,PPP2R3A,SKI,NKX6-1,SETDB2,EOMES,ACVR2A,LRP6,DYNC2H1,SMAD6,BARX1,GLI1,NKX2-1,PCSK6,EPB41L5,INTU,MSX1,WLS,MAFB,SMARCD3,ACVR2B,DKK1,SMAD3,WDR19,PCGF2,SEMA3C,HOXD13,DISP1,BMPR1A,BMP4,DLX2,NRP1,SEMA3A,HOXB9,MLLT3,COBL,SIX2,DDIT3,FOXA1,PCSK5,MEF2C |
| 1.315e-04 | -8.94 | WW | pfam domains | PF00397 | 37 | 12 | 17054 | 1666 |
BAG3,PLEKHA5,APBB1,WWTR1,HECW2,YAP1,WWC1,WWC2,SAV1,MAGI2,MAGI3,NEDD4 |
| 1.321e-04 | -8.93 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_UP | 172 | 33 | 17377 | 1707 |
RGS16,CLGN,ELOVL7,TBC1D30,PHLDA2,F3,MCOLN2,RASSF8,OTUD1,PIK3AP1,CNKSR3,MAP7,MET,TBC1D9,SMPDL3A,KIAA1211,MYO10,AGPAT4,GJB2,TGFA,STAT4,FERMT2,PDE8A,BATF,SAV1,STEAP1,AKT3,MFSD2A,SVIL,TNFSF15,PLD1,SLC16A10,HEY1 |
| 1.321e-04 | -8.93 | GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_DN | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_DN | 172 | 33 | 17377 | 1707 |
OR51B5,ACSL1,TTC39B,TCTN2,OTOGL,BLVRB,HERC5,DNER,ABHD6,SYDE2,TMEM53,SIPA1L2,TSC22D1,PCOLCE2,RNF148,PARP9,PGBD5,PHLDB2,KCNQ3,CRIM1,AGPAT4,GDPD1,DNAJC6,EFHC2,VLDLR,TCERG1L,TBC1D2,IRS2,TMEM237,PRKCB,SVIL,DISP1,OSBPL6 |
| 1.332e-04 | -8.92 | SUNG_METASTASIS_STROMA_UP | MSigDB lists | SUNG_METASTASIS_STROMA_UP | 103 | 23 | 17377 | 1707 |
CD55,SEC24D,FZD8,CD276,XYLT1,EPS8,BNIP3L,ASS1,PSD3,SCD,TMEM47,SEL1L3,DCBLD2,DKK1,HMGCS1,IGIP,PLOD2,PLK2,P4HA1,UACA,PTPRS,PROS1,SNAI2 |
| 1.338e-04 | -8.92 | ion transport | biological process | GO:0006811 | 1291 | 163 | 17256 | 1658 |
ACSL1,CACNG3,FGF13,GRIK2,ATP8A1,LDLR,MCOLN3,ITPR2,SLC2A13,CACNB4,SLCO3A1,SLC9A7,NCS1,KCNAB1,KCNN2,SLC16A2,SLC22A18,PPFIA2,SLC10A7,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,PLTP,GPM6A,KCNIP3,SLC3A2,ABCC4,KLHL3,SLC9C1,ANK2,ATOX1,JPH1,SLC25A28,ABCC2,KCND3,SGK2,CA13,SFXN1,SLC7A1,ENPP1,KCNMB4,ATP7B,SLC9B1,PRKAA2,KCNV1,SCN5A,TMEM63C,GABRB2,SCN8A,ATP6V1E2,SLC36A4,SLC1A3,APBA1,MLC1,MCOLN2,SLC30A4,CA2,SLC7A11,CACNB2,PRELID2,PRELID1,SLC16A9,NIPAL2,SLCO4C1,FAM155A,STXBP1,NDUFA4L2,SLC37A1,KCNQ3,SLC36A1,SLC27A2,PPFIA4,RYR2,TTYH2,CALCRL,NPC2,SNAP25,STEAP1,KCNK15,CACHD1,TMCO3,GRIK4,MFSD2A,SLC2A6,SH3BP4,TRPC3,PLA2G4A,PRKN,SLC7A2,SLC19A2,SLC22A17,UNC13B,CHRNA5,FABP6,STEAP3,FAM155B,SCN2A,ATP6AP1L,KCNB2,SCN3A,CSN2,LRRC8B,SLC39A8,KCNH5,SFXN4,CYB5R2,CHRNA6,ATP1B1,ASPH,ATP10D,GJC1,SNCA,SLC39A14,KCNG1,ASIC1,DENND5B,ANO10,SERINC5,SLC6A9,ATP9A,GABRG2,GAS6,SLC12A6,GABRR2,NDFIP2,SFXN3,KCNC4,MCU,LRRC55,KCNJ4,SCN1B,BHLHA15,KCNMB3,SGK3,SGK1,SLC6A15,SYK,ATP2B1,TMC7,TRPM4,SLC40A1,CACNA1E,GRID1,RASA3,ATP11A,PTPRC,OSBPL5,SLC7A5,SLCO5A1,GRIN2D,SLC22A15,SLC1A5,SLC16A10,CACNA2D1,ATP2B4,DDIT3,ABCG1,ATP1A3,SLC43A1,TPT1 |
| 1.343e-04 | -8.92 | cell body | cellular component | GO:0044297 | 519 | 75 | 18223 | 1724 |
PDE1B,GRIK2,C4A,KIF5A,ASS1,CANX,NRXN1,DNER,RAC3,PPP1R9A,TUBB4A,KCNAB1,KCNN2,DAB2IP,CPE,KCNB2,GPM6A,SHANK2,LRRK2,FEZ1,EFHC1,PRKAR2B,KCND3,AMIGO1,CD40,TTLL7,GABARAPL1,SNCA,CAMK2N1,MAP2,RGS10,PAM,PTPRS,INPP5F,SERPINI1,BMPR1A,PPARGC1A,NRP1,COBL,CTNND2,PRKAA2,MYO1D,ENO2,BMPR2,LRP4,APBB1,SLC25A27,KIF5C,SLC1A3,P2RY1,KCNC4,GDPD5,MAP1A,PDE10A,ACTA2,LRP6,NPTXR,ZNF385A,ATP2B1,DPYSL5,TRPM4,MYO10,PTPN13,RAPGEF2,HOMER2,RACK1,BAIAP2,MAP1B,SH3GL2,RPL28,GNAO1,CTSV,SHTN1,SNPH,ATP1A3 |
| 1.344e-04 | -8.91 | regulation of cell migration | biological process | GO:0030334 | 858 | 115 | 17256 | 1658 |
NBL1,AMOTL1,ACVR1,DOCK1,RHOD,RECK,ATP8A1,PLXNA2,COL18A1,GATA3,NTRK3,PRKCA,ABHD6,SEMA6A,STK24,F3,RND2,TCAF2,RAP2A,ITGB3,DAB2IP,MET,SLIT2,DOCK8,SNAI2,PDGFRB,IGFBP3,NKX2-1,CYP1B1,PHLDB2,FER,EVL,GCNT2,ACVR1C,PTPRU,PREX1,WNT11,RARRES2,SYNJ2BP,CD40,DOCK5,JAM3,FGFR1,IRS2,SMAD3,CXCL10,NRG3,PTPRJ,NCKAP1L,CCBE1,PLK2,APELA,ITGA2,ABI3,LAMB1,HGF,SEMA3C,BMPR1A,TPM1,NRP1,PPARGC1A,TMEFF2,MAGI2,FRMD5,MEF2C,HACE1,FN1,BMPR2,LGALS3,RHOBTB1,ITGA6,SLK,GAS6,PFN2,PHLDA2,MTUS1,NKX6-1,IGF1R,SEMA4F,GATA2,SRGAP1,SGK3,PRKG1,SGK1,RRAS2,SPRY2,NOS3,EPB41L5,PAK1,VEGFC,UNC5C,MPP1,RAPGEF2,SPATA13,RACK1,PLCB1,GPLD1,BEX4,PTPRC,FGR,DOCK7,MYADM,RIPOR2,RND3,TERT,GCSAM,THBS4,PRCP,CSF1,AKT3,XBP1,MCC,BMP4,SEMA3A,SHTN1 |
| 1.346e-04 | -8.91 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP | 165 | 32 | 17377 | 1707 |
MXI1,LPAR2,ITPRIP,GPR65,UBASH3B,YPEL2,DENND3,DDIT4,TRPS1,OTUD1,BAG3,FBXO32,ZFYVE28,TSC22D1,SGK1,PDE4D,IPCEF1,SP140L,DUSP1,SUSD3,VNN2,CSN2,KLHL3,EFHC2,BNIP3L,ZNF711,IRS2,ARHGAP21,PTPRJ,MPP7,PELI2,LPP |
| 1.350e-04 | -8.91 | GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_DN | MSigDB lists | GSE37319_WT_VS_RC3H1_KO_CD44LOW_CD8_TCELL_DN | 130 | 27 | 17377 | 1707 |
FER,EHHADH,SLC27A2,TGFA,YPEL2,SPATA13,NFE2L1,MORC4,RNF125,PHACTR2,KCND3,PPP2R3A,DAGLA,UNC13B,TACC2,BACE2,PLXDC2,PPFIBP1,PLK2,GHR,RUNDC3B,MPPED2,ADCY6,STON2,RAPGEF5,CHMP4C,SLC43A1 |
| 1.350e-04 | -8.91 | V$GATA4_Q3 | MSigDB lists | V$GATA4_Q3 | 231 | 41 | 17377 | 1707 |
CXCR5,RASAL2,CHCHD7,PLAG1,PLXNA2,TNFRSF19,IKZF2,FOXP2,CHN2,LHX6,ZNF521,BCL6,RTKN2,BEND4,PDE4D,SMAD6,SCN3A,NKX2-1,MID2,PPP1R3D,MEIS2,CSN2,ESRRG,SLC25A28,TEX9,GPC6,ZIC1,EBF1,TMEM154,SLCO5A1,EGFL7,DLG2,BMP4,PPARGC1A,NRP1,SEMA3A,NEUROG2,FNBP1L,LIFR,ATP2B4,TPT1 |
| 1.359e-04 | -8.90 | GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_DN | 194 | 36 | 17377 | 1707 |
CREB3L2,SERINC5,ZNF395,IGFBP6,RNF144A,PTPRD,ATP9A,UGDH,XYLT1,SELL,IGF2BP2,ISYNA1,NEDD4,PLS3,IGF1R,FAM168A,RRAS2,SNX10,GATM,SCN3A,B4GALT6,GAB2,FADS1,VAV3,ABCC4,STAT4,TES,LITAF,CR2,EIF4EBP1,HK2,SH3BP4,RNF130,TNFSF4,DHCR7,MME |
| 1.359e-04 | -8.90 | GSE360_DC_VS_MAC_T_GONDII_DN | MSigDB lists | GSE360_DC_VS_MAC_T_GONDII_DN | 194 | 36 | 17377 | 1707 |
ARHGAP26,EFNB2,CACNG3,EHHADH,ENO2,RASAL2,KIF5A,ITGA6,KCTD12,CTBP2,CTNNA2,F3,RPS6KA2,MCF2L,RUNDC3B,NDUFB8,BNIP3,CPE,CKAP4,SMPDL3A,CEBPD,VNN2,TGFA,BNIP3L,SLITRK5,SDC3,HERPUD1,INSIG1,RND3,AKT3,KCNG1,TECPR2,GEM,SLC1A5,SEMA3A,ABCG1 |
| 1.360e-04 | -8.90 | lamellipodium | cellular component | GO:0030027 | 186 | 34 | 18223 | 1724 |
WASF3,AMOTL1,INPPL1,APBB1,ENAH,RAC3,PPP1R9A,CTNNA2,TIAM2,ABLIM1,ITGB3,ACTA2,CTTN,DOCK8,PAK1,FER,PXN,EVL,MYO10,PTPN13,SPATA13,FERMT2,CDC42BPA,PALLD,SLC39A14,GSN,PLEKHH2,SH3RF1,FAT1,ABI3,MCC,CDH2,TESC,SHTN1 |
| 1.370e-04 | -8.90 | YNGTTNNNATT_UNKNOWN | MSigDB lists | YNGTTNNNATT_UNKNOWN | 347 | 56 | 17377 | 1707 |
TYRO3,MXI1,ACVR1,SEC24D,PTPRD,KLHL13,GABRG2,ZIC2,NTRK3,SATB1,IKZF2,SPINK5,FAM110B,CBLN1,NEDD4,FOXP2,GPR15,ABLIM1,CHN2,KCTD15,EOMES,IKZF5,FLRT3,LHX6,STC2,CHRDL1,ZNF521,ATRNL1,SLC2A12,BEND4,KLF9,FIGN,VGLL4,ETV1,POU3F3,FES,DPP10,BDNF,PCDH10,THSD4,ESRRG,FOXN3,CACNA1E,ELMOD1,PRDM1,ROR1,ZFPM2,CLN5,PLCB1,GPR150,IFT81,GNAO1,CLMN,BMP4,SEMA3A,SHOX2 |
| 1.375e-04 | -8.89 | GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 151 | 30 | 17377 | 1707 |
PLA2G4A,MTG1,ALOX5AP,CFH,SCAMP1,DOCK1,HEBP1,GDPD1,PHACTR2,CTBP2,VIM,CCNG1,ARHGAP32,WDFY4,DOCK5,SLC46A3,COL14A1,PLS3,MGAT1,PRKCB,GPR155,OSBPL5,RAB31,ALPK1,RNF130,MET,VWA5A,TPM1,TBC1D9,TBC1D8 |
| 1.376e-04 | -8.89 | GO_PATTERN_SPECIFICATION_PROCESS | MSigDB lists | GO_PATTERN_SPECIFICATION_PROCESS | 411 | 64 | 17377 | 1707 |
NBL1,ACVR1,CELSR1,BMPR2,LRP4,OTX1,RGS20,PLXNA2,OVOL2,CHSY1,PGAP1,SP8,PPP2R3A,SKI,NKX6-1,SETDB2,EOMES,LRRC6,LRP6,ACVR2A,DYNC2H1,SMAD6,DNAH5,BARX1,PCSK6,GLI1,NKX2-1,INTU,EPB41L5,RAX,MICAL2,MSX1,NKX3-2,WLS,SMARCD3,MAFB,SATB2,ACVR2B,ASPH,ZIC1,DKK1,SMAD3,ARMC4,NRG3,WDR19,PCGF2,DYNC2LI1,SEMA3C,HOXD13,DLX2,BMP4,DISP1,BMPR1A,NRP1,HOXB9,SEMA3A,MLLT3,MID1,COBL,FOXA1,DDIT3,SIX2,PCSK5,MEF2C |
| 1.378e-04 | -8.89 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4538 | 507 | 17385 | 1698 |
ARHGAP26,MYCBP2,CGN,PAGE1,ACVR1,LANCL3,DUSP8,LGR4,AASS,DNAJC3,LDLR,PPFIBP2,GATA3,NPM1,STAT5B,ADAMTS6,CADM2,PRKCA,SNX9,RAC3,DACH2,SLC9A7,STK24,HECTD2,NOS1AP,SKI,PCDH7,TRPS1,BAG3,FBXO32,PMAIP1,SLC16A2,PPFIA2,FAAH2,RAP2A,RAB26,CHRDL1,PPP2R2B,NKX2-1,SMAD9,ACVR1C,TGFA,KLHL4,LRRK2,DNAJC6,LRMP,BNIP3L,DEPTOR,FEZ1,PRKAR2B,ACVR2B,SAV1,ZDHHC14,INTS6,GNAI1,AHRR,HLF,PLK2,RASGRF2,ALDOA,ADRB1,BBC3,MAPK13,ERCC5,INPP5F,DIRAS1,SERPINI1,SPRY4,UNC5B,LPP,MEF2C,CARS,KLF8,GNG12,LATS2,INPPL1,ALOX5AP,PTPRD,ITGA6,MLF1,ST6GAL1,OPHN1,BTBD9,GPSM2,TNFRSF10C,TNFRSF19,FOXG1,BBS9,CHD5,GAS1,MECOM,CHN1,NAV1,BNIP1,RALGPS2,FRY,NOVA2,ADCK1,MYC,PRKG1,SRGAP1,CPXM2,MPDZ,TOX,ALPK1,LOXL4,SAMD13,RIMS2,HMGCR,RNF152,PTCH2,RPL26,PNP,TBC1D8B,PLEKHA8,COL4A4,STAT4,RAPGEF4,EFHC2,RYR2,HIP1,SMARCD3,CCDC85A,CDC42BPA,RABAC1,PLCB1,FAM162A,TMEM74,DHX32,MMP15,BEX4,PMEPA1,ADAMTS3,PKN3,CLMN,HOXD13,SPRED3,FBXO27,IQSEC2,DHCR7,SMYD3,AMPD1,PLA2G4A,FRMPD3,EPHA3,PCSK1N,DNM3,RNF144A,TMSB15A,RHOD,RGS20,CHUK,IL13RA1,GRK6,COLEC10,DDR1,COL14A1,ZFYVE9,CCDC120,RNF150,SPEG,DACT1,ALDOC,STARD4,FAM133A,NAP1L3,PJA1,PDE4D,FAM155B,ARL4D,RAB27B,SERPINH1,DNAH5,SNX10,FZD1,GAB2,TRDMT1,VNN2,MYLK3,GAPDH,PDK1,FZD4,PREX1,NLGN4X,WNT11,PNMA6A,PRKCQ,ATF3,RAB38,PYGO1,FGFR1,GJC1,ZNF711,IRS2,CXCL10,ARHGAP21,IKZF3,PRKCB,CCNA1,INPP4B,TNFSF15,GRB10,BMPR1A,MID1,RAB30,HACE1,FARP1,MXI1,EDA2R,FZD8,PLAG1,BIK,IPO5,ARL2,HERC5,GAS6,PKN1,EPHB1,RGS7,INPP1,TSPAN17,BEX2,NEDD4,RGS17,AFF2,PCBP4,MCF2L,GAS2L3,GHR,SGK3,SMAD6,SPRY2,ZFP36L2,MED12L,FES,BCL7A,VAV3,ALDH2,PXN,RAB6B,CACNA1E,MCF2L2,RAPGEF2,PTPN13,MPP1,ZDHHC15,AK4,RASA3,SNTB1,GPLD1,CEBPB,PTPRC,TRIB3,ID3,FGR,TERT,GNAO1,AKT3,XBP1,NEK11,PIP5KL1,BMP4,HK1,TNFRSF17,DDIT3,BTRC,FOXA1,TRIM2,FGF13,TRIM16,PTPN21,ITPR2,NUP62CL,IKZF2,NOVA1,KREMEN1,FKBP11,PLS3,ARHGEF10L,RND2,PPM1E,FKBP9,RPS6KA2,AKAP7,ITGB3,POF1B,HRK,CTTN,TMEM132E,PTPRE,ENO1,ETV1,RAPGEF5,RASGRP1,PDGFRB,PRKACB,ITGB7,TNK2,MARK1,SESN2,COL4A3,YAP1,CR2,ROR1,PLEKHA1,TMEM47,COTL1,SGK2,BATF,RNF44,SESN1,SERGEF,PLEKHB1,DYRK1B,TRIM9,AK1,KCNMB4,HPSE,GNB4,TECPR2,ERN1,TNFRSF1A,NCOA7,PIK3C2B,TNFSF4,PPARGC1A,MLLT3,RRAGD,KCNV1,PRKAA2,BCL11B,RGS16,RUNX2,RHOBTB1,JDP2,FBXO4,SETBP1,SATB1,DOK5,HSPA12B,DDIT4,RNF141,NUMBL,IGF1R,GATA2,PDE10A,LRP6,BNIP3,RNF148,PTPRCAP,FBXL2,SNX7,PAK1,FGFR4,MID2,RHOQ,SLITRK2,MSTN,SPATA13,PPFIA4,SDC3,STRADB,OBSCN,MAFB,DUSP9,PRDM1,KHDRBS2,MAPKAPK2,CSAG1,HK2,RAB31,PTPRN2,PLD1,RNF122,NKX2-8,FNBP1L,SFN,CXCR5,NEK10,ID1,CFH,AKAP5,DOCK1,PLEKHA5,PSTPIP2,ARHGAP22,HECW2,MORC4,RNF24,BCL6B,NTRK3,KIF21B,PPP1R9A,SEMA6A,PCLO,SLC22A17,CDC14B,TACC2,PPFIBP1,RPS6KL1,MYO3B,ZNF521,BCL6,ACVR2A,MET,POU2F2,HSPA2,GLI1,SUSD3,FER,PTPRU,PTPN6,FGF12,ACO1,RNF125,VIM,CD40,FBXO36,FRK,PAGE5,TPK1,BCL11A,SMAD3,MAGEA12,RANBP2,PTPRJ,KPNA3,BACH2,TRIM34,PTK7,EIF4EBP1,ITGA2,RGS10,DUSP19,PTPRS,MAOA,DISP1,RNF130,SEPT5,LIFR,CTNND2,CNTN1,MAST1,HEY1,TNIK,PCDH18,DYRK3,ENO2,BMPR2,KLHL13,ARHGEF11,GRB14,REL,NLRP14,TNFSF13B,IGF2BP2,COL4A5,RASD1,USP30,PPP2R3A,FOXP2,CHN2,PRKCD,RASD2,TRIM3,SGK1,PCK2,RRAS2,SYK,FKBP14,TNFRSF11A,ATP2B1,DUSP1,DLGAP1,RIN2,PPP1R3D,CARD6,RAB3B,USP2,FOXN3,CRIP2,SYBU,CYTH3,LITAF,NUAK2,PRRG1,MARS,AGAP2,CCNG1,ARHGAP32,PALLD,MGMT,DKK1,ADAMTS17,SUGT1,EDA,RND3,MAP2K6,FMO4,SH3BGRL2,PAX9,GEM,RNF157,IL9R,PTGES,KIF1B,MMP16 |
| 1.387e-04 | -8.88 | GO_POSITIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT | 37 | 12 | 17377 | 1707 |
SMAD3,PLA2G4A,ACVR1,BMPR2,CD276,TFAP2A,ACVR2A,ACVR2B,BMPR1A,BMP4,BMP6,MEF2C |
| 1.392e-04 | -8.88 | negative regulation of supramolecular fiber organization | biological process | GO:1902904 | 126 | 26 | 17256 | 1658 |
PRKN,PHLDB2,FGF13,TMSB15A,CKAP2,LDLR,EPS8,ADD2,HDGFL3,CHADL,PFN2,PPP1R9A,FHOD3,SNCA,SCIN,TUBB4A,GSN,PLEKHH2,MYADM,PRKCD,ARHGAP28,TMOD2,MET,TMEFF2,SLIT2,MID1 |
| 1.400e-04 | -8.87 | cation channel activity | molecular function | GO:0005261 | 318 | 52 | 17224 | 1680 |
KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,SCN8A,MCOLN3,ITPR2,GAS6,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,KCNH5,CACNA1E,JPH1,CHRNA6,RASA3,RYR2,KCND3,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B |
| 1.401e-04 | -8.87 | synapse organization | biological process | GO:0050808 | 191 | 35 | 17256 | 1658 |
DNM3,FARP1,PTPRD,LRP4,COL4A5,EPHB1,NRXN1,CACNB4,DNER,PCLO,NEDD4,ARHGAP44,PCDHB14,UNC13B,IGF1R,CACNB2,FLRT3,CTTN,ZNF365,FZD1,BDNF,GPM6A,SYBU,LRRK2,SHANK2,NFIA,NLGN4X,SDK1,DKK1,SNCA,ADGRB3,PCDHB7,MAGI2,CDH2,CTNND2 |
| 1.403e-04 | -8.87 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | 187 | 35 | 17377 | 1707 |
GNG12,ENO2,SCAMP1,UBASH3B,ITGA6,SELL,NDRG2,SCD,NDFIP2,SNX9,SEC16B,AKAP7,CNKSR3,MYC,MED7,RAPGEF5,NEB,RIN2,LCA5,GSTM4,MPP1,WLS,GSTO1,C3orf70,PEAK1,SESN1,ENTPD1,TMEM237,PTPRS,P4HA1,TANC2,LARP1,CSRP2,PHC1,RRAGD |
| 1.403e-04 | -8.87 | GO_REGULATION_OF_TRANSPORTER_ACTIVITY | MSigDB lists | GO_REGULATION_OF_TRANSPORTER_ACTIVITY | 187 | 35 | 17377 | 1707 |
CACNG3,GRK6,NRXN1,NDFIP2,CACNB4,NEDD4,NOS1AP,KCNAB1,AKAP7,SCN1B,CACNB2,PRKCD,SGK3,SGK1,PDE4D,SYNGR3,HSPA2,GSTM2,ANK2,JPH1,FGF12,RYR2,GSTO1,ATP1B1,CTTNBP2NL,SGK2,ASPH,SNCA,KCNG1,BMP4,PPARGC1A,TESC,CACNA2D1,STOM,MEF2C |
| 1.403e-04 | -8.87 | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 187 | 35 | 17377 | 1707 |
FN1,CLGN,RBFOX2,FZD8,IPO5,CEBPA,CTBP2,STK24,PCDH7,PLS3,SEMA4F,SLC22A18,ZDHHC6,PRKCD,FAM107B,ADCY6,ARL4D,GFI1,PTPRE,PRKACB,GLDC,HBG2,PNP,AK4,C1orf174,TSKU,IRS2,KPNA3,CSF1,P4HA2,EIF4EBP1,DUSP19,KLF5,CMPK2,LIFR |
| 1.403e-04 | -8.87 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | 187 | 35 | 17377 | 1707 |
AVPI1,IGFBP6,TBC1D1,ARHGAP22,CEBPA,F3,ARHGEF10L,EPB41L3,PRKCD,TSC22D1,SGK1,PTPRE,SPRY2,SYK,CAND2,CKAP4,CYP1B1,RIN2,QSOX1,LRRC8B,ATOX1,TNS1,PLEKHA1,NPC2,SAV1,TTC28,SLC46A3,GSN,FGR,PLK2,KIAA0513,RNF130,NRP1,KIF1B,NR3C2 |
| 1.409e-04 | -8.87 | embryonic morphogenesis | biological process | GO:0048598 | 546 | 79 | 17256 | 1658 |
ACVR1,ST14,RECK,UGDH,OTX1,GATA3,SP8,SKI,SETDB2,EOMES,DLX6,DACT1,ITGB3,MYO3B,TBC1D32,ACVR2A,PRKACB,GLI1,FZD1,INTU,NKX3-2,WLS,YAP1,SATB2,WNT11,ACVR2B,ATOH1,FGFR1,SMAD3,INSIG1,PTK7,APELA,RBPMS2,LAMB1,ITGA2,DLX2,BMPR1A,COBL,MEF2C,RUNX2,CELSR1,BMPR2,FN1,LRP4,OVOL2,FOXG1,EFEMP1,IRX5,PDZD7,GATA2,FRAS1,FLRT3,TFAP2A,LRP6,DYNC2H1,SPRY2,DUSP1,EPB41L5,B9D1,VEGFC,MICAL2,MSX1,MAFB,PRICKLE1,RYR2,RACK1,HOXA1,ZIC1,DKK1,MMP15,FBN1,WDR19,PCGF2,HOXD13,BMP4,SHOX2,MAP3K20,MMP16,SIX2 |
| 1.410e-04 | -8.87 | regulation of MAPK cascade | biological process | GO:0043408 | 762 | 104 | 17256 | 1658 |
EPHA3,PRKN,ID1,NEK10,AVPI1,DUSP8,GRIK2,NDRG2,NTRK3,PRKCA,DDR1,STK24,GSDME,TLR3,TGFBR3,DACT1,CNKSR3,RAP2A,DAB2IP,EPHB6,MET,TLR4,RASGRP1,PDGFRB,IGFBP3,GCNT2,FZD4,PTPN6,TGFA,LRRK2,ATF3,ROR1,SYNJ2BP,CD40,FGFR1,MAGI3,CAMK2N1,INHBC,PTPRJ,SH3RF1,GBP1,APELA,ERN1,MAP3K21,TNFRSF1A,DUSP19,HGF,DIRAS1,SPRY4,NRP1,MAPK10,MID1,TENM1,TYRO3,TNIK,NECAB2,FN1,EDA2R,PAK5,FZD8,SORBS3,GAS6,P2RY1,TNFRSF10C,PKN1,EPHB1,TPD52L1,TNFRSF19,BMP6,MECOM,IGF1R,MYC,PRKCD,GHR,C1QL4,INAVA,ERRFI1,IQGAP3,TNFRSF11A,SYK,SPRY2,HMGCR,DUSP1,PAK1,FGFR4,MSTN,RAPGEF2,WWC1,DUSP9,PDE8A,GAREM1,PLCB1,TLR6,DKK1,MAPKAPK2,GPR37,TRIB3,PELI2,MAP2K6,INHBE,BMP4,SEMA3A,CDH2,MAP3K20 |
| 1.412e-04 | -8.87 | lung-carcinoid-endocrine_tumour | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour | 504 | 75 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,LGR4,GALNT6,CHUK,CEBPA,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PRKACB,PDGFRB,TBC1D8,INTU,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,TANC2,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PKN1,EPHB1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,DHX32,MAP1B,MAPKAPK2,TRIB3,FGR,PKN3,AKT3,MAP2K6,NEK11 |
| 1.424e-04 | -8.86 | functioning | COSMIC cancer mutations | functioning | 1848 | 226 | 17385 | 1698 |
EXPH5,MYCBP2,PPP4R4,TCP11L2,GRIK2,KIF5A,ATP8A1,PTPN21,CA8,HMCN1,CEP85L,PCDH7,SIPA1L2,IKZF5,KCNN2,SEC16B,DNAH6,ABI3BP,MARVELD2,COL19A1,POF1B,TLN2,MYRIP,NEB,SLC3A2,MEIS2,DCC,KLHL3,ANK2,GDPD1,FEZ1,F12,MFSD6,ZDHHC14,INTS6,SERGEF,NT5DC2,AHRR,TCF7L1,HPSE,MAP9,SEMA3C,ZBTB20,OXTR,DNHD1,MAGI2,SPOCK3,RRAGD,LGALS3,STXBP5L,SEC24D,PTPRD,ZHX3,SCN8A,ITGA6,ST6GAL1,CYP4V2,MRPL22,GALNT13,CHSY1,WDFY4,SPINK5,GRPEL2,MTUS1,EFEMP1,SYCP2,KIAA1958,KIAA0895,SEMA4F,ZNF354A,FRY,KIAA1671,BCHE,FRAS1,EBF4,SRGAP1,GRIP1,CADPS2,ALPK1,FIGN,MOXD1,FAM155A,GPR161,CHRM3,ZNF629,IL17RD,PCDH10,QSOX1,UNC5C,MYO10,SH2D2A,PPFIA4,RYR2,SDK1,LHPP,TBC1D2,NAP1L5,GRIK4,TEX15,RIMKLB,KIAA0355,FAT1,MATN2,HK2,ACSM3,EML5,CFH,DOCK1,PLEKHA5,CCDC110,MYO1B,PLXNA2,BEGAIN,MSR1,PKP2,NTRK3,TNKS1BP1,TBC1D30,PPP1R9A,DOCK2,SEMA6A,PCLO,TIAM2,ZSCAN5A,NELL2,TMEM53,RNF150,COL22A1,SETDB2,ALDOC,PPFIBP1,FABP6,LHX6,ALDH1L1,SCRN1,NBEA,DAB2IP,CLVS2,ARL4D,RAB27B,DNAH5,GATM,KCNB2,SCN3A,DOCK8,IGFBP3,C3orf67,PTPN6,ACO1,CHRNA6,WNT11,VIM,PRKCQ,DSP,ATP10D,DCBLD2,WARS,ENTPD1,IFT81,NRG3,GYPC,TDO2,LAMB1,INPP4B,PAM,PTPRS,MAOA,GRB10,HOXB9,CNTN1,TENM1,PCDH18,CCDC148,FARP1,ARHGEF11,CLGN,ATP9A,FZD8,ESRP1,CLSTN2,KIF5C,PRDM8,P2RY1,ZNF219,GDPD5,TECPR1,SOAT2,AFF2,STC2,EHD3,TSC22D1,KIAA0319,PRICKLE2,IPCEF1,IQGAP3,PCK2,ATP2B1,MED12L,PDLIM7,TRPM4,BCL7A,MICAL2,ARHGEF28,SYNPO2,HNF4G,NR4A1,PTPN13,GRID1,CTTNBP2NL,ARHGAP32,FNDC3A,SKAP1,RERE,GPR37,DPY19L2,MPP7,CLDN12,SLC7A5,SLCO5A1,NEK11,UACA,SVIL,KIAA0513,PGM2L1,OCLN,TLL2 |
| 1.424e-04 | -8.86 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | 1848 | 226 | 17385 | 1698 |
EXPH5,MYCBP2,PPP4R4,TCP11L2,GRIK2,KIF5A,ATP8A1,PTPN21,CA8,HMCN1,CEP85L,PCDH7,SIPA1L2,IKZF5,KCNN2,SEC16B,DNAH6,ABI3BP,MARVELD2,COL19A1,POF1B,TLN2,MYRIP,NEB,SLC3A2,MEIS2,DCC,KLHL3,ANK2,GDPD1,FEZ1,F12,MFSD6,ZDHHC14,INTS6,SERGEF,NT5DC2,AHRR,TCF7L1,HPSE,MAP9,SEMA3C,ZBTB20,OXTR,DNHD1,MAGI2,SPOCK3,RRAGD,LGALS3,STXBP5L,SEC24D,PTPRD,ZHX3,SCN8A,ITGA6,ST6GAL1,CYP4V2,MRPL22,GALNT13,CHSY1,WDFY4,SPINK5,GRPEL2,MTUS1,EFEMP1,SYCP2,KIAA1958,KIAA0895,SEMA4F,ZNF354A,FRY,KIAA1671,BCHE,FRAS1,EBF4,SRGAP1,GRIP1,CADPS2,ALPK1,FIGN,MOXD1,FAM155A,GPR161,CHRM3,ZNF629,IL17RD,PCDH10,QSOX1,UNC5C,MYO10,SH2D2A,PPFIA4,RYR2,SDK1,LHPP,TBC1D2,NAP1L5,GRIK4,TEX15,RIMKLB,KIAA0355,FAT1,MATN2,HK2,ACSM3,EML5,CFH,DOCK1,PLEKHA5,CCDC110,MYO1B,PLXNA2,BEGAIN,MSR1,PKP2,NTRK3,TNKS1BP1,TBC1D30,PPP1R9A,DOCK2,SEMA6A,PCLO,TIAM2,ZSCAN5A,NELL2,TMEM53,RNF150,COL22A1,SETDB2,ALDOC,PPFIBP1,FABP6,LHX6,ALDH1L1,SCRN1,NBEA,DAB2IP,CLVS2,ARL4D,RAB27B,DNAH5,GATM,KCNB2,SCN3A,DOCK8,IGFBP3,C3orf67,PTPN6,ACO1,CHRNA6,WNT11,VIM,PRKCQ,DSP,ATP10D,DCBLD2,WARS,ENTPD1,IFT81,NRG3,GYPC,TDO2,LAMB1,INPP4B,PAM,PTPRS,MAOA,GRB10,HOXB9,CNTN1,TENM1,PCDH18,CCDC148,FARP1,ARHGEF11,CLGN,ATP9A,FZD8,ESRP1,CLSTN2,KIF5C,PRDM8,P2RY1,ZNF219,GDPD5,TECPR1,SOAT2,AFF2,STC2,EHD3,TSC22D1,KIAA0319,PRICKLE2,IPCEF1,IQGAP3,PCK2,ATP2B1,MED12L,PDLIM7,TRPM4,BCL7A,MICAL2,ARHGEF28,SYNPO2,HNF4G,NR4A1,PTPN13,GRID1,CTTNBP2NL,ARHGAP32,FNDC3A,SKAP1,RERE,GPR37,DPY19L2,MPP7,CLDN12,SLC7A5,SLCO5A1,NEK11,UACA,SVIL,KIAA0513,PGM2L1,OCLN,TLL2 |
| 1.430e-04 | -8.85 | positive regulation of cellular protein metabolic process | biological process | GO:0032270 | 1542 | 190 | 17256 | 1658 |
ACSL1,ACVR1,FGF13,DNAJC3,LDLR,GATA3,NPM1,CEBPA,PRKCA,SNX9,STK24,NOS1AP,F3,GSDME,PMAIP1,RAP2A,ITGB3,EPHB6,PCOLCE2,TLR4,ENO1,PRKACB,RASGRP1,PDGFRB,TNK2,GCNT2,COL4A3,ACVR1C,TGFA,LRRK2,PRKAR2B,ACVR2B,ROR1,F12,INHBC,GSN,GPRC5B,NCKAP1L,CCBE1,PLK2,ERN1,TNFRSF1A,BBC3,DIRAS1,NRP1,PPARGC1A,MAGI2,CACUL1,PRKAA2,LONRF1,TYRO3,FN1,FBXO4,SLK,JDP2,SORBS3,TNFRSF10C,PFN2,TNFRSF19,RNF180,EEF2,IGF1R,MYC,PRELID1,SREBF1,ADCY6,INAVA,PRR16,HMGCR,PAK1,FGFR4,RPL26,ATP5IF1,MSTN,VLDLR,EFNA3,PACSIN3,DUSP9,WWC1,STRADB,HIP1,PDE8A,ARRDC4,PLCB1,FAM162A,HERPUD1,MAPKAPK2,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,EPHA3,PRKN,NEK10,AVPI1,RNF144A,IL15,NTRK3,LCP2,TNKS1BP1,DDR1,PIBF1,PPP1R9A,TLR3,CDC14B,DACT1,BCL6,ACVR2A,DAB2IP,MET,HSPA2,PERP,IGFBP3,ALG10B,FZD1,FZD4,NOP53,ADCY1,RNF125,VIM,WNT11,RARRES2,CD40,ASPH,FGFR1,SNCA,SMAD3,NRG3,RNF217,BEX3,APELA,WFS1,ITGA2,MAP3K21,DUSP19,TNFSF15,HGF,BMPR1A,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,LRP4,GAS6,P2RY1,PKN1,NDFIP2,EPHB1,TPD52L1,BMP6,PRKCD,RASD2,GHR,AFAP1L2,YBX3,IQGAP3,TNFRSF11A,SYK,SPRY2,PARP9,VEGFC,RAPGEF2,PRICKLE1,GAREM1,RACK1,TLR6,GPLD1,DKK1,GPR37,PTPRC,TRIB3,DOCK7,ACER2,MAP2K6,XBP1,LRRK1,BMP4,MAP3K20,BTRC,LARP1,ATP2B4 |
| 1.433e-04 | -8.85 | GO_HIPPO_SIGNALING | MSigDB lists | GO_HIPPO_SIGNALING | 27 | 10 | 17377 | 1707 |
MOB1B,LATS2,AMOTL1,FAT4,WWTR1,DCHS1,WWC1,YAP1,TJP1,SAV1 |
| 1.436e-04 | -8.85 | small GTPase mediated signal transduction | biological process | GO:0007264 | 315 | 51 | 17256 | 1658 |
CELSR1,ARHGEF11,DOCK1,RHOBTB1,RHOD,PAK5,EPS8,DHCR24,CHUK,GPSM2,DOCK3,DOCK2,RAC3,RND2,RALGPS2,CNKSR3,RAP2A,RAB26,BCL6,IPCEF1,IQGAP3,RAB27B,RRAS2,RAPGEF5,DOCK8,RASGRP1,PAK1,TNK2,RIN2,VAV3,RHOQ,RAB3B,RAB6B,RAPGEF2,RAPGEF4,ARHGAP32,RAB38,SYNJ2BP,DOCK5,MAPKAPK2,DOCK7,RND3,RASGRF2,PLK2,RAB31,PLD1,DOCK6,RAB30,SHTN1,DOCK9,HACE1 |
| 1.436e-04 | -8.85 | regionalization | biological process | GO:0003002 | 315 | 51 | 17256 | 1658 |
NBL1,CELSR1,BMPR2,LRP4,OTX1,PLXNA2,CHSY1,OVOL2,FOXG1,PGAP1,SP8,SKI,NKX6-1,SETDB2,EOMES,TBC1D32,LRP6,ACVR2A,DYNC2H1,SMAD6,BARX1,PCSK6,GLI1,NKX2-1,EPB41L5,INTU,MSX1,WLS,MAFB,SMARCD3,ACVR2B,DKK1,SMAD3,WDR19,PCGF2,SEMA3C,HOXD13,BMPR1A,DISP1,BMP4,DLX2,NRP1,HOXB9,SEMA3A,COBL,MLLT3,FOXA1,SIX2,DDIT3,MEF2C,PCSK5 |
| 1.439e-04 | -8.85 | protein serine/threonine kinase activity | molecular function | GO:0004674 | 505 | 75 | 17224 | 1680 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PDGFRB,PRKACB,TNK2,MYLK3,MARK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,GRK3,FGFR1,DYRK1B,PRKCB,PLK2,ERN1,MAP3K21,MAPK13,BMPR1A,MAPK10,MAST1,TYRO3,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,MAPKAPK2,PKN3,MAP2K6,AKT3,PELI2,NEK11,LRRK1,MAP3K20 |
| 1.443e-04 | -8.84 | sterol biosynthetic process | biological process | GO:0016126 | 49 | 14 | 17256 | 1658 |
PRKAA2,CYP51A1,IDI1,MVK,HMGCS1,ERG28,INSIG1,MSMO1,CYB5R2,MVD,DHCR24,SQLE,DHCR7,HMGCR |
| 1.456e-04 | -8.83 | V$FOX_Q2 | MSigDB lists | V$FOX_Q2 | 202 | 37 | 17377 | 1707 |
BCL11B,FARP1,FGF13,CHCHD7,PLAG1,CEBPA,COLEC10,DOCK3,HMCN1,NEO1,FOXP2,ATXN7L1,EFEMP1,SLC10A7,ZIC5,PRICKLE2,KLF9,NCAM1,ERRFI1,MYT1,FKBP14,GFRA1,GCNT2,CRIM1,PLEKHA8,SLC39A8,ESRRG,KCNH5,NFIA,PRKAR2B,PRDM1,GABARAPL1,KLF12,ITGBL1,GNAO1,ZBTB20,MEF2C |
| 1.457e-04 | -8.83 | anterograde trans-synaptic signaling | biological process | GO:0098916 | 454 | 68 | 17256 | 1658 |
DOC2A,PRKN,GRIK2,AKAP5,SYT12,KIF5A,SYT14,NRXN1,CACNB4,NOVA1,RAC3,PCLO,PPP1R9A,CBLN1,CHRNA5,UNC13B,PPFIA2,LIN7A,LRRK2,FGF12,CHRNA6,SNCA,GJC1,TRIM9,HTR7,KCNMB4,TMOD2,SEPT5,APBA2,TC2N,MEF2C,SV2B,SLC6A9,GABRB2,GABRG2,SLC1A3,SLC12A6,GABRR2,APBA1,KCNC4,PCDHB14,SCN1B,CACNB2,RASD2,KCNMB3,LRP6,CADPS2,STXBP1,RIMS2,CHRM3,DLGAP1,GPR176,KCNQ3,CACNA1E,GRID1,SLITRK5,PPFIA4,SNAP25,OR11H4,GPR19,GRIK4,PCDHB7,MPP2,PTPRN2,DLG2,GRIN2D,KIF1B,SNPH |
| 1.457e-04 | -8.83 | chemical synaptic transmission | biological process | GO:0007268 | 454 | 68 | 17256 | 1658 |
DOC2A,PRKN,GRIK2,AKAP5,SYT12,KIF5A,SYT14,NRXN1,CACNB4,NOVA1,RAC3,PCLO,PPP1R9A,CBLN1,CHRNA5,UNC13B,PPFIA2,LIN7A,LRRK2,FGF12,CHRNA6,SNCA,GJC1,TRIM9,HTR7,KCNMB4,TMOD2,SEPT5,APBA2,TC2N,MEF2C,SV2B,SLC6A9,GABRB2,GABRG2,SLC1A3,SLC12A6,GABRR2,APBA1,KCNC4,PCDHB14,SCN1B,CACNB2,RASD2,KCNMB3,LRP6,CADPS2,STXBP1,RIMS2,CHRM3,DLGAP1,GPR176,KCNQ3,CACNA1E,GRID1,SLITRK5,PPFIA4,SNAP25,OR11H4,GPR19,GRIK4,PCDHB7,MPP2,PTPRN2,DLG2,GRIN2D,KIF1B,SNPH |
| 1.458e-04 | -8.83 | MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 | 332 | 54 | 17377 | 1707 |
SCN5A,CELSR1,STXBP5L,CLGN,SYT12,BIK,CLSTN2,GALNT13,NOTUM,OVOL2,SYT14,KCNC4,FOXG1,BMP6,PHLDA2,SP8,CYP26A1,NKX6-1,GATA2,LHX6,KCNS3,SERINC2,CADPS2,HRK,NPTXR,FAM155B,SLCO4C1,TMEM132E,PRR16,MYRIP,FAM155A,DOCK8,PGBD5,NKX2-1,DPP10,EIF4E3,GJB2,RYR2,GALNT14,CPEB1,HTR7,MSC,IKZF3,P4HA2,PTPRN2,HOXD13,PLD5,TESC,COBL,XKR4,SIX2,OCLN,ABCG1,MAST1 |
| 1.458e-04 | -8.83 | GO_NEUTRAL_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_NEUTRAL_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 32 | 11 | 17377 | 1707 |
SERINC5,SLC3A2,SLC6A9,SLC7A11,SLC36A1,SLC7A5,SERINC2,SLC36A4,SLC6A15,SLC1A5,SLC43A1 |
| 1.459e-04 | -8.83 | transmembrane receptor protein tyrosine kinase activity | molecular function | GO:0004714 | 66 | 17 | 17224 | 1680 |
EPHA3,FGFR4,TYRO3,CRIM1,EFNA3,NTRK3,ROR1,EPHB1,DDR1,FGFR1,EFEMP1,IGF1R,MAP3K21,EPHB6,NRP1,MET,PDGFRB |
| 1.462e-04 | -8.83 | GTPase binding | molecular function | GO:0051020 | 657 | 93 | 17224 | 1680 |
EXPH5,DMXL2,BTC,DOCK1,DOCK3,DENND3,DOCK2,TBC1D30,PPP1R9A,TIAM2,ARHGEF10L,ADPRHL1,UNC13B,HPS1,RTKN2,MET,MYRIP,ENO1,RAPGEF5,DOCK8,RASGRP1,PDGFRB,TBC1D8,LRRK2,PREX1,FGF17,DOCK5,TBC1D16,SERGEF,FGFR1,ARHGEF26,IRS2,RANBP2,RASGRF2,PLEKHG1,ADRB1,HGF,RRAGD,ARFGEF3,HACE1,DENND5B,FARP1,STXBP5L,ARHGEF11,PAK5,TBC1D1,RUSC2,STXBP6,IPO5,EPS8,PSD3,PKN1,ARHGAP44,RAB11FIP5,RALGPS2,MCF2L,SRGAP1,BNIP3,IQGAP3,TBC1D9,DENND1C,YBX3,NCAM1,FMNL2,GFRA1,RIMS2,RNF152,FGFR4,PAK1,RIN2,VAV3,ARHGEF28,ARAP2,TBC1D8B,RAPGEF2,MCF2L2,CYTH3,RAPGEF4,ASAP3,SPATA13,OBSCN,AGAP2,PEX5L,TBC1D2,DOCK7,PKN3,SH3BP4,GRIN2D,IQSEC2,FNBP1L,TBC1D4,DOCK6,DOCK9 |
| 1.463e-04 | -8.83 | blood vessel morphogenesis | biological process | GO:0048514 | 388 | 60 | 17256 | 1658 |
EFNB2,AMOTL1,ACVR1,ID1,FN1,BMPR2,FZD8,ARHGAP22,COL18A1,OVOL2,SLC12A6,EPHB1,PRKCA,TYMP,TGFBR3,ITGB3,TSPAN12,DAB2IP,LOXL4,SYK,SLIT2,PDGFRB,NOS3,CYP1B1,FGFR4,VEGFC,ATP5IF1,VAV3,CEMIP2,ADM2,FZD4,SH2D2A,NR4A1,CALCRL,YAP1,WNT11,PRDM1,ZFPM2,HOXA1,LEPR,JAM3,FGFR1,GPLD1,WARS,GJC1,HEG1,HPSE,PRCP,CCBE1,APELA,XBP1,HPGD,EGFL7,KLF5,BMPR1A,BMP4,UNC5B,NRP1,CDH2,HEY1 |
| 1.471e-04 | -8.82 | GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | MSigDB lists | GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 340 | 55 | 17377 | 1707 |
CELSR1,ARHGEF11,RHOBTB1,DOCK1,RHOD,ARL15,EPS8,DHCR24,ARL2,RASL11B,RASD1,CHUK,DOCK3,DOCK2,RAC3,RND2,RALGPS2,RASD2,RAP2A,RAB26,BCL6,IQGAP3,ARL4D,RAB27B,RRAS2,RAPGEF5,RASGRP1,DOCK8,TNK2,VAV3,RIN2,RHOQ,RAB3B,RAB6B,RAPGEF2,RAPGEF4,LRRK2,AGAP2,SYNJ2BP,RAB38,DOCK5,MAPKAPK2,DOCK7,RND3,PLK2,RASGRF2,RAB31,DIRAS1,LRRK1,PLD1,GEM,DOCK6,RAB30,HACE1,DOCK9 |
| 1.473e-04 | -8.82 | breast-carcinoma-ER-PR-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-PR-positive_carcinoma | 1914 | 233 | 17385 | 1698 |
ARHGAP26,THOC5,UGT8,ACVR1,FGF13,FAM227A,GATA3,NPM1,STAT5B,CEBPA,PRKCA,DNER,KREMEN1,STK24,HECTD2,SKI,EPDR1,RUFY4,FBXO32,RPS6KA2,DNAH6,PMAIP1,RAP2A,PPP2R2B,TLN2,ETV1,TLR4,TSHR,RAPGEF5,PRKACB,PDGFRB,NKX2-1,DBN1,ACVR1C,TGFA,YAP1,FEZ1,PRKAR2B,ROR1,FGF17,ACVR2B,SGK2,SAV1,INTS6,RNF44,TCF7L1,GPRC5B,SH3RF1,RASGRF2,TNFRSF1A,ADRB1,NCOA7,BBC3,MAPK13,ERCC5,PIK3C2B,DIRAS1,SPRY4,NRP1,TMEFF2,MAGI2,MLLT3,LPP,MEF2C,BCL11B,PRKAA2,CARS,LATS2,INPPL1,FN1,CELSR1,PTPRD,MLF1,JDP2,RASL11B,FOXG1,FHOD3,MECOM,SYCP2,NUMBL,OTUD1,IGF1R,GATA2,MYC,LRP6,FAM84B,SAMD13,FMNL2,NOS3,PAK1,FGFR4,PTCH2,IL17RD,STAT4,EDEM3,RYR2,TTC30A,HIP1,CALCRL,OBSCN,MAFB,DUSP9,PLS1,STEAP1,MAPKAPK2,NCR3LG1,CECR2,SQLE,EGFL7,HOXD13,PLD1,CDH2,SFN,CXCR5,EPHA3,PLA2G4A,BTC,CFH,RHOD,HECW2,CHUK,NTRK3,KIF21B,DDR1,RADIL,SPEG,TLR3,KMO,BCL6,ACVR2A,MET,SCN3A,FZD1,IGFBP3,GAB2,C3orf67,PDK1,RNF145,FZD4,PTPN6,FGF12,WNT11,PRKCQ,ATF3,CD40,TTLL7,FGFR1,MAGI3,BCL11A,IRS2,RANBP2,NRG3,IKZF3,PRKCB,PTK7,EIF4EBP1,GRB10,BMPR1A,SEPT5,LIFR,CNTN1,HACE1,HEY1,TENM1,FARP1,LPAR2,IL32,BMPR2,IGFBP6,FZD8,PLAG1,REL,MCTP2,SSX1,TNFSF13B,HERC5,PRDM8,RASD1,P2RY1,PKN1,EPHB1,USP30,PPP2R3A,NEDD4,MAP1A,PRKCD,GHR,RASD2,SGK3,SGK1,RRAS2,SYK,SPRY2,TNFRSF11A,ZFP36L2,MED12L,DUSP1,PARP9,MN1,RIN2,PPP1R3D,BCL7A,VAV3,PXN,USP2,SYNPO2,CACNA1E,RAPGEF2,OGDHL,RASA3,UCHL3,GUCY1A2,TLR6,MGMT,MAP1B,DKK1,GPR37,FAT4,TERT,RND3,MAP2K6,AKT3,GNAO1,NUTM2A,GRIN2D,BMP4,KIF21A,TNFRSF17,GEM,KIF1B,BTRC,DDIT3,ABCG1 |
| 1.473e-04 | -8.82 | ER-PR-positive_carcinoma | COSMIC cancer mutations | ER-PR-positive_carcinoma | 1914 | 233 | 17385 | 1698 |
ARHGAP26,THOC5,UGT8,ACVR1,FGF13,FAM227A,GATA3,NPM1,STAT5B,CEBPA,PRKCA,DNER,KREMEN1,STK24,HECTD2,SKI,EPDR1,RUFY4,FBXO32,RPS6KA2,DNAH6,PMAIP1,RAP2A,PPP2R2B,TLN2,ETV1,TLR4,TSHR,RAPGEF5,PRKACB,PDGFRB,NKX2-1,DBN1,ACVR1C,TGFA,YAP1,FEZ1,PRKAR2B,ROR1,FGF17,ACVR2B,SGK2,SAV1,INTS6,RNF44,TCF7L1,GPRC5B,SH3RF1,RASGRF2,TNFRSF1A,ADRB1,NCOA7,BBC3,MAPK13,ERCC5,PIK3C2B,DIRAS1,SPRY4,NRP1,TMEFF2,MAGI2,MLLT3,LPP,MEF2C,BCL11B,PRKAA2,CARS,LATS2,INPPL1,FN1,CELSR1,PTPRD,MLF1,JDP2,RASL11B,FOXG1,FHOD3,MECOM,SYCP2,NUMBL,OTUD1,IGF1R,GATA2,MYC,LRP6,FAM84B,SAMD13,FMNL2,NOS3,PAK1,FGFR4,PTCH2,IL17RD,STAT4,EDEM3,RYR2,TTC30A,HIP1,CALCRL,OBSCN,MAFB,DUSP9,PLS1,STEAP1,MAPKAPK2,NCR3LG1,CECR2,SQLE,EGFL7,HOXD13,PLD1,CDH2,SFN,CXCR5,EPHA3,PLA2G4A,BTC,CFH,RHOD,HECW2,CHUK,NTRK3,KIF21B,DDR1,RADIL,SPEG,TLR3,KMO,BCL6,ACVR2A,MET,SCN3A,FZD1,IGFBP3,GAB2,C3orf67,PDK1,RNF145,FZD4,PTPN6,FGF12,WNT11,PRKCQ,ATF3,CD40,TTLL7,FGFR1,MAGI3,BCL11A,IRS2,RANBP2,NRG3,IKZF3,PRKCB,PTK7,EIF4EBP1,GRB10,BMPR1A,SEPT5,LIFR,CNTN1,HACE1,HEY1,TENM1,FARP1,LPAR2,IL32,BMPR2,IGFBP6,FZD8,PLAG1,REL,MCTP2,SSX1,TNFSF13B,HERC5,PRDM8,RASD1,P2RY1,PKN1,EPHB1,USP30,PPP2R3A,NEDD4,MAP1A,PRKCD,GHR,RASD2,SGK3,SGK1,RRAS2,SYK,SPRY2,TNFRSF11A,ZFP36L2,MED12L,DUSP1,PARP9,MN1,RIN2,PPP1R3D,BCL7A,VAV3,PXN,USP2,SYNPO2,CACNA1E,RAPGEF2,OGDHL,RASA3,UCHL3,GUCY1A2,TLR6,MGMT,MAP1B,DKK1,GPR37,FAT4,TERT,RND3,MAP2K6,AKT3,GNAO1,NUTM2A,GRIN2D,BMP4,KIF21A,TNFRSF17,GEM,KIF1B,BTRC,DDIT3,ABCG1 |
| 1.482e-04 | -8.82 | GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_LARGE_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | 173 | 33 | 17377 | 1707 |
ANO10,FGF13,LMCD1,SYT14,IKZF2,HECTD2,EPDR1,BAG3,ABLIM1,FAM107B,TOX,ENO1,GFRA1,RASGRP1,PDGFRB,EVL,RAPGEF2,PTPN13,TMTC4,RNF125,PRKCQ,MBNL2,CENPV,HEG1,SMAD3,IKZF3,IQCH,SH3RF1,RGS10,UACA,MBOAT2,PSPH,DOCK9 |
| 1.482e-04 | -8.82 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | 173 | 33 | 17377 | 1707 |
COL9A3,SETBP1,LILRB1,COBLL1,SEL1L3,DENND3,KMO,EHD3,PRKCD,OPN3,SCRN1,TSPAN13,MARCKS,FIG4,TBC1D9,SYK,SCN3A,RHOQ,SKAP2,SLC37A1,LRMP,CD40,ATP10D,BCL11A,CD37,FGR,PRCP,SLC2A6,RAB31,CLMN,LRRK1,TNFRSF17,MEF2C |
| 1.487e-04 | -8.81 | response to organic cyclic compound | biological process | GO:0014070 | 869 | 116 | 17256 | 1658 |
PRKN,ID1,ACSL1,IL15,RBFOX2,ASS1,NPM1,CEBPA,NTRK3,STAT5B,ITPR2,ABAT,PLPP1,FBXO32,TLR3,ASNS,PMAIP1,PDE4D,SLIT2,PRKACB,PDGFRB,GLDC,CYP1B1,GDAP1,SLC3A2,ATF4,SMAD9,PTPRU,NR6A1,LRRK2,ADCY1,YAP1,PRKAR2B,AGO4,ABCC2,CD40,SNCA,GNAI1,SMAD3,GSN,CXCL10,INSIG1,EIF4EBP1,ITGA2,PAM,HPGD,KLF5,OXTR,PPARGC1A,NR3C2,PSPH,HEY1,MEF2C,HID1,GABRB2,ITGA6,SELL,GABRG2,HBE1,P2RY1,MLC1,BMP6,NEDD4,DDIT4,FOXP2,HMGCS1,EEF2,CA2,ZNF354A,BCHE,DSG2,STC2,SREBF1,LRP6,GRIP1,ADCY6,KLF9,ERRFI1,PCK2,AGL,STXBP1,ZFP36L2,ATP2B1,DUSP1,TRPM4,FGFR4,GSTM2,MSTN,HNF4G,NR4A1,RAPGEF2,ESRRG,HOMER2,FHL2,RYR2,SDK1,MGMT,GPLD1,MMP15,CEBPB,ID3,TERT,PMEPA1,GNAO1,CTSV,HOXD13,BMP4,TRPC3,PTGES,KIF1B,SMYD3,FOXA1,BTRC,ATP2B4,LARP1,ATP1A3 |
| 1.488e-04 | -8.81 | dendrite cytoplasm | cellular component | GO:0032839 | 28 | 10 | 18223 | 1724 |
KCNAB1,GRIK2,MAP2,WLS,KIF5A,LRRK2,ABHD13,CANX,BAIAP2,GABARAPL1 |
| 1.488e-04 | -8.81 | cell-cell adhesion | biological process | GO:0098609 | 446 | 67 | 17256 | 1658 |
ACVR1,CELSR3,PKP2,ADD2,CADM2,NRXN1,COL14A1,CBLN1,CTNNA2,PCDH7,EPCAM,ITGB3,ADGRL1,COL19A1,PERP,CYP1B1,FER,ITGB7,PTPRU,PTPN6,NLGN4X,AMIGO1,DSP,JAM3,GYPC,NCAM2,LAMB1,CTNND2,TENM1,TYRO3,PCDH18,ROBO2,CELSR1,BVES,PTPRD,UBASH3B,STXBP6,ITGA6,SELL,CLSTN2,GAS6,PCDHB14,SLC7A11,CNTN4,FLRT3,DSG2,SCARF2,LRP6,STXBP1,JAM2,SYK,CDH26,PCDH10,PODXL2,DCHS1,SDK1,FNDC3A,BAIAP2,NEGR1,FAT4,PCDHB7,FAT1,CLDN12,THBS4,CDH17,CDH2,NPHP1 |
| 1.496e-04 | -8.81 | NADH metabolic process | biological process | GO:0006734 | 38 | 12 | 17256 | 1658 |
GAPDH,ENO2,ALDOC,ALDOA,HK2,PGM2L1,HK1,MDH1B,PCK2,ENO1,NUDT12,NUDT17 |
| 1.496e-04 | -8.81 | ion channel complex | cellular component | GO:0034702 | 296 | 48 | 18223 | 1724 |
KCNV1,SCN5A,CACNG3,GRIK2,GABRB2,SCN8A,GABRG2,GABRR2,KCNC4,CACNB4,ABHD6,NOS1AP,MCU,LRRC55,KCNJ4,KCNAB1,CHRNA5,SCN1B,CACNB2,KCNMB3,KCNS3,CTTN,PDE4D,SCN2A,HSPA2,SCN3A,KCNB2,DPP10,TRPM4,KCNIP3,KCNQ3,LRRC8B,CACNA1E,SHANK2,TTYH2,RYR2,CHRNA6,CATSPERE,AMIGO1,KCND3,SNAP25,HERPUD1,GRIK4,KCNMB4,KCNG1,DLG2,GRIN2D,CACNA2D1 |
| 1.538e-04 | -8.78 | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN | 159 | 31 | 17377 | 1707 |
CD55,EVL,PDK1,SIDT1,RNF144A,ST6GAL1,RAPGEF4,FASN,NPC2,GRK6,PLEKHA1,CD7,SESN1,SATB1,KBTBD11,TEX9,ID3,ABLIM1,TGFBR3,EEF2,RALGPS2,MYC,INPP4B,RGS10,RCN3,TSPAN13,TOX,PACSIN1,RRAS2,AMPD1,ABCG1 |
| 1.538e-04 | -8.78 | GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_UP | MSigDB lists | GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_UP | 159 | 31 | 17377 | 1707 |
RPS20,PRKAA2,FADS1,BCL7A,SLC40A1,MXI1,TSPAN15,CLGN,RASA3,BTBD9,ARHGAP32,TNFRSF10C,CD40,SATB1,IKZF2,NUDT12,SLC19A2,CYP26A1,EPB41L3,SETDB2,KMO,GNB4,WDR19,ATRNL1,TRPC1,TSPAN13,ERCC5,GULP1,RAB30,SCN3A,ACSM3 |
| 1.538e-04 | -8.78 | GARCIA_TARGETS_OF_FLI1_AND_DAX1_UP | MSigDB lists | GARCIA_TARGETS_OF_FLI1_AND_DAX1_UP | 54 | 15 | 17377 | 1707 |
DPY19L2,INPPL1,KCNMB4,KDM5B,NKX3-2,COL25A1,ATP7B,WDR19,ARID5B,SVIL,C20orf194,MYO6,PGAP1,FKBP14,SEMA6A |
| 1.544e-04 | -8.78 | ALK_DN.V1_UP | MSigDB lists | ALK_DN.V1_UP | 131 | 27 | 17377 | 1707 |
CXCR5,VEGFC,VNN2,SLC6A9,FLVCR2,BEGAIN,CBS,PRDM1,SLC1A3,CHAC1,MLC1,DDIT4,TRIB3,ASNS,CA2,SLC7A11,PDZD7,TDO2,DLX6,STC2,XBP1,SLC7A5,INHBE,PCK2,SLC1A5,ETV1,CTH |
| 1.554e-04 | -8.77 | HOOI_ST7_TARGETS_DN | MSigDB lists | HOOI_ST7_TARGETS_DN | 104 | 23 | 17377 | 1707 |
PFKFB4,GXYLT2,RIN2,PCSK1N,PDK1,ENO2,FN1,TBC1D8B,CNTNAP3,MCOLN3,VIM,PGAP1,FAM131B,KCTD15,GPR160,RAP2A,CADPS2,SPRY4,VWA5A,DNAH5,MLLT3,FOXA1,TMEM56 |
| 1.554e-04 | -8.77 | GO_REGULATION_OF_SYNAPSE_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_SYNAPSE_ORGANIZATION | 104 | 23 | 17377 | 1707 |
BDNF,DISC1,SLITRK2,ROBO2,LRP4,CLSTN2,SLITRK5,NTRK3,AMIGO1,EPHB1,NRXN1,PPP1R9A,CBLN1,CTNNA2,NEDD4,DKK1,LRRN1,FLRT3,DAB2IP,OXTR,CDH2,MAGI2,MEF2C |
| 1.557e-04 | -8.77 | activin-activated receptor activity | molecular function | GO:0017002 | 7 | 5 | 17224 | 1680 |
ACVR2A,ACVR2B,ACVR1,BMPR2,ACVR1C |
| 1.562e-04 | -8.76 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | 145 | 29 | 17377 | 1707 |
BDNF,SLC40A1,RHOBTB1,DNAJC6,GDPD1,FHL2,HERC5,PRKAR2B,ISYNA1,PALLD,HERC6,RBM11,TTC28,DDIT4,HOPX,MECOM,NEGR1,NAP1L5,GBP1,ATP7B,FAT1,CNKSR3,ADRB1,TSC22D1,MAP7,HS3ST3B1,RAB27B,OSBPL6,MEF2C |
| 1.565e-04 | -8.76 | GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP | MSigDB lists | GSE13522_WT_VS_IFNAR_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP | 188 | 35 | 17377 | 1707 |
RNF144A,YPEL2,CHSY1,PRKCA,IKZF2,SLC19A2,HOPX,GPR15,ZNF827,GRHL1,PRELID2,MYO3B,TSPAN13,TOX,MYO6,GFI1,CPE,PARP9,PTPRU,WLS,CYTH3,GSTO1,NPDC1,ISG20,ENPP1,IKZF3,PMEPA1,PELI2,PLXDC2,GPR160,NCOA7,RGS10,PTPRS,CMPK2,TBC1D4 |
| 1.565e-04 | -8.76 | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_DN | 188 | 35 | 17377 | 1707 |
MOCOS,RGS16,ACSL1,DUSP8,CFH,TJP1,CANX,TNKS1BP1,PCLO,EPCAM,KCNAB1,EOMES,TRPC1,GSTM3,COL19A1,EPHB6,SERPINH1,MYO6,ETV1,PERP,GDAP1,PHLDB2,LITAF,YAP1,PRDM1,TPK1,PTPRJ,DOCK7,MAP2,CSF1,RASGRF2,ENTPD7,TNFRSF1A,GEM,FRMD5 |
| 1.565e-04 | -8.76 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_DN | 188 | 35 | 17377 | 1707 |
CCDC126,ARHGAP26,FARP1,RNF144A,RHOD,KCTD12,GABRR2,ISYNA1,ABHD4,KBTBD11,SLCO3A1,ASNS,GRHL1,MYC,LIN7A,NCEH1,ARL4D,SPRY2,FES,C3orf67,TRPM4,TMEM126A,FHL2,LITAF,TTYH2,PHACTR2,PLS1,LHPP,TBC1D16,PELI2,OSBPL5,RAB31,PLD1,SLC22A15,MAPK10 |
| 1.567e-04 | -8.76 | channel regulator activity | molecular function | GO:0016247 | 132 | 27 | 17224 | 1680 |
DPP10,KCNV1,KCNIP3,CACNG3,FGF13,VAMP8,FGF12,PACSIN3,PKP2,AMIGO1,RACK1,SGK2,NRXN1,HPCAL4,NEDD4,GPLD1,LRRC55,KCNMB4,KCNAB1,SCN1B,KCNMB3,KCNS3,PRKG1,SGK3,SGK1,TSPAN13,ATP2B4 |
| 1.584e-04 | -8.75 | GO_MUSCLE_STRUCTURE_DEVELOPMENT | MSigDB lists | GO_MUSCLE_STRUCTURE_DEVELOPMENT | 413 | 64 | 17377 | 1707 |
ACVR1,BVES,ASS1,PKP2,CHUK,DNER,CACNB4,PPP2R3A,FHOD3,SKI,FOXP2,SPEG,TGFBR3,EOMES,EEF2,KCNAB1,SMTN,COL19A1,MYH15,ETV1,NEB,PDGFRB,HMGCR,FZD1,MSX1,USP2,MYLK3,MSTN,ANK2,ARID5B,JPH1,FHL2,MEF2B,RYR2,SMARCD3,OBSCN,ATF3,CBY1,ZFPM2,DSP,HEG1,MKX,DYRK1B,ID3,MSC,CXCL10,HLF,PLAGL1,HEYL,XBP1,SVIL,KLF5,TMOD2,DISP1,BMP4,ATG5,TPM1,KLHL31,CDH2,SHOX2,SMYD3,CSRP2,HEY1,MEF2C |
| 1.588e-04 | -8.75 | ZHANG_GATA6_TARGETS_DN | MSigDB lists | ZHANG_GATA6_TARGETS_DN | 60 | 16 | 17377 | 1707 |
IDI1,COL4A3,INSIG1,MSMO1,AKAP5,COL4A4,MVD,LDLR,SLCO4C1,GALNT14,DHCR7,SEMA3A,SLCO3A1,DCBLD1,LAMP3,TXNRD3 |
| 1.606e-04 | -8.74 | TIAN_BHLHA15_TARGETS | MSigDB lists | TIAN_BHLHA15_TARGETS | 14 | 7 | 17377 | 1707 |
C2orf88,SERPINI1,TIFA,DISP1,FNDC3A,FIGN,RAB26 |
| 1.606e-04 | -8.74 | MATTIOLI_MULTIPLE_MYELOMA_SUBGROUPS | MSigDB lists | MATTIOLI_MULTIPLE_MYELOMA_SUBGROUPS | 14 | 7 | 17377 | 1707 |
MAGEA12,KLF9,MAGEA6,FGF13,MAGEA3,SSX1,GABARAPL1 |
| 1.611e-04 | -8.73 | phospholipid binding | molecular function | GO:0005543 | 408 | 63 | 17224 | 1680 |
ARHGAP26,PLA2G4A,DOC2A,SYT12,STXBP6,PLEKHA5,MYO1B,MCTP2,OPHN1,JCHAIN,ITPR2,GAS6,SYT14,SNX9,NUP62CL,PFN2,PCLO,ZFYVE9,ARHGAP44,F3,SCIN,GSDME,TECPR1,UNC13B,ZFYVE28,MCF2L,RUNDC3B,SGK3,DAB2IP,SH3PXD2B,CLVS2,DENND1C,PACSIN1,SNX10,PLTP,RASGRP1,FES,SNX7,GAB2,ARAP2,MARK1,MYO10,PLEKHA8,RAPGEF2,PARD3B,CYTH3,PACSIN3,PREX1,FERMT2,HIP1,ARHGAP32,PLEKHA1,PLCB1,SNCA,FCHO2,PEMT,OSBPL5,LAPTM4B,PIK3C2B,PLD1,PXDC1,TC2N,ABCG1 |
| 1.614e-04 | -8.73 | ESC_J1_UP_LATE.V1_UP | MSigDB lists | ESC_J1_UP_LATE.V1_UP | 181 | 34 | 17377 | 1707 |
GNG12,FARP1,FLVCR2,PRSS12,VAMP8,PTPN21,MORC4,SEL1L3,CYP26A1,F3,RAB11FIP5,TGFBR3,SOAT2,MYO6,SLC40A1,ARAP2,CD55,RAB6B,CRIM1,SLC39A8,WLS,FHL2,PRICKLE1,ATF3,DSP,IRS2,GSN,P4HA2,LAMB1,TUFT1,P4HA1,RNF130,UNC5B,OCLN |
| 1.614e-04 | -8.73 | GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP | 181 | 34 | 17377 | 1707 |
BCL11B,TNIK,IL32,ENO2,SIDT1,RNF144A,GALNT12,ITGA6,KIF21B,PRKCA,CD7,SATB1,ABLIM1,NELL2,ALDOC,BNIP3,PJA1,PTPRCAP,EVL,PRKCQ,SKAP1,SESN1,FAM162A,PLEKHB1,DEXI,BACH2,GYPC,INPP4B,TBC1D4,SMYD3,MLLT3,NR3C2,PKIA,DOCK9 |
| 1.626e-04 | -8.72 | GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING | MSigDB lists | GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_ACTIVITY_SEQUENCE_SPECIFIC_DNA_BINDING | 612 | 88 | 17377 | 1707 |
CREB3L2,OTX1,GATA3,BCL6B,CEBPA,STAT5B,DACH2,ZSCAN5A,TRPS1,GRHL1,BCL6,POU2F2,ETV1,SNAI2,GLI1,NKX2-1,MEIS2,KCNIP3,ATF4,NR6A1,NKX3-2,SOX21,NFIA,NFE2L1,MEF2B,ATF3,ATOH1,BATF,BATF3,BCL11A,SMAD3,MSC,IKZF3,KLF12,BACH2,KLF5,ZBTB20,DLX2,DBP,BMPR1A,HEY1,MEF2C,BCL11B,RUNX2,REL,PLAG1,JDP2,GTF2IRD1,OVOL2,ZNF219,SATB1,FOXG1,NKX6-1,FOXP2,KIAA1958,GATA2,MYC,BHLHA15,EBF4,TFAP2A,SREBF1,GFI1,ZNF518B,GLIS1,BARX1,CEBPD,RAX,MSX1,HNF4G,NR4A1,ESRRG,ARID5B,MAFB,PRDM1,ZFPM2,ZIC1,CEBPB,EBF1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SIX2,DDIT3,FOXA1 |
| 1.631e-04 | -8.72 | establishment of localization | biological process | GO:0051234 | 4314 | 476 | 17256 | 1658 |
DOC2A,THOC5,SIDT1,FLVCR2,GRIK2,PRSS12,ATP8A1,DNAJC3,LDLR,VAMP8,MCOLN3,GATA3,NPM1,STAT5B,SNX9,RAC3,SLC9A7,NCS1,PCDH7,TRPS1,TXNDC5,PMAIP1,SLC16A2,SLC22A18,PPFIA2,RAP2A,RAB26,KCNS3,SERINC2,NDUFB8,TMED9,TMEM37,COG3,PACSIN1,PLTP,TBC1D8,GDAP1,ERGIC1,KLHL3,SLC9C1,WLS,EXOC6B,TGFA,LRRK2,DNAJC6,LRMP,BNIP3L,FEZ1,SLC25A28,ABCC2,KCND3,ACVR2B,ZDHHC14,CA13,SFXN1,SLC7A1,ENPP1,WIPF3,NCKAP1L,ATP7B,ALDOA,BBC3,MFSD4A,INPP5F,NRP1,SCN5A,TMEM63C,INPPL1,MRC2,TBC1D1,GABRB2,SCN8A,OPHN1,SLC25A27,SLC36A4,GPSM2,SLC1A3,APBA1,DYNC1I1,BBS9,TTC30B,RPL13A,GRPEL2,MCOLN2,BNIP1,SLC7A11,PDZD7,CACNB2,MYC,PRELID2,PRELID1,SLC16A9,LMAN2,CADPS2,LOXL4,DENND1C,AGL,STXBP1,FAM155A,RPS23,LRP12,CHRM3,RIMS2,BOD1,RPL26,QSOX1,SLC37A1,PNP,KCNQ3,MYO10,TBC1D8B,SLC36A1,PLEKHA8,VLDLR,RAPGEF4,PACSIN3,RYR2,TTYH2,HIP1,TTC30A,CALCRL,PLS1,PEX5L,NPC2,SNAP25,ARRDC4,CLN5,CACHD1,TMCO3,VPS37D,SH3GL2,RPL28,CECR2,WDR19,CDH17,DYNC2LI1,SELENOM,LAPTM4B,TRPC3,SMYD3,PLA2G4A,FRMPD3,DNM3,SCAMP1,RHOD,MYO1B,MSR1,ADD2,NRXN1,LCP2,DDR1,SLC19A2,TBC1D30,ZFYVE9,CHRNA5,ALDOC,STARD4,SCRN1,FAM155B,ARL4D,RAB27B,SYNGR3,SNX10,ATP6AP1L,SCN3A,KCNB2,FZD4,CYB5R2,SFXN4,KCNH5,TRAM1L1,NLGN4X,ATP1B1,RAB38,DSP,ASPH,TBC1D16,ATP10D,SNCA,GJC1,SLC39A14,ARHGAP21,PRKCB,ASIC1,PAM,STON2,RAB30,THOC3,DENND5B,RPS20,ANO10,MYO1D,SERINC5,ATP9A,CLBA1,IPO5,KIF5C,GAS6,GABRR2,SLC12A6,NDFIP2,SELENOP,KCNC4,TSPAN17,NEDD4,LRRC55,SOAT2,GPR155,BHLHA15,GHR,SGK3,SLC6A15,DYNC2H1,MYO6,TBC1D9,SPRY2,PDLIM7,TRPM4,VEGFC,TMC7,SLC40A1,VAV3,ARAP2,LCA5,RAB6B,CACNA1E,RPL21,ZDHHC15,RASA3,ATP11A,GPLD1,PTPRC,FGR,RPL12,TERT,OSBPL5,XBP1,MCC,SLCO5A1,GRIN2D,HK1,JHY,DDIT3,ATP2B4,TPT1,SLC43A1,ATP1A3,EXPH5,ACSL1,CACNG3,FGF13,SYT12,KIF5A,JCHAIN,LILRB1,ITPR2,SLC2A13,SYT14,CACNB4,NUP62CL,DNER,SLCO3A1,ADPRHL1,KCNAB1,SEC16B,KCNN2,SLC10A7,ITGB3,TRPC1,LIN7A,CNNM2,SLC2A12,CTTN,MYRIP,TLR4,IL1RAP,RASGRP1,TNK2,GPM6A,CD55,KCNIP3,SESN2,SLC3A2,ABCC4,ANK2,ATOX1,JPH1,PLEKHA1,COTL1,SGK2,GRK3,SPNS1,TRIM9,GSN,KCNMB4,HPSE,OXTR,APBA2,TC2N,SLC9B1,CHMP4C,PCSK5,PRKAA2,KCNV1,TYRO3,SV2B,FN1,STXBP5L,LGALS3,HID1,SEC24D,SCART1,BVES,STXBP6,ATP6V1E2,MLC1,PGAP1,SPIRE1,EEF2,SLC30A4,CA2,ABCA5,GATA2,FRAS1,RPS11,LRP6,BNIP3,NIPAL2,SLCO4C1,LRP3,CKAP4,SNX7,PAK1,NDUFA4L2,HBG2,ATP5IF1,RHOQ,SLC27A2,PPFIA4,STRADB,SLC46A3,STEAP1,HERPUD1,BAIAP2,TBC1D2,MAPKAPK2,KCNK15,GRIK4,FCHO2,MFSD2A,SLC2A6,SH3BP4,RAB31,HK2,PTPRN2,PLD1,FNBP1L,OSBPL6,TESC,SIX2,MME,SFN,CREB3L2,PRKN,AKAP5,DOCK1,SLC7A2,CANX,DENND3,PIBF1,PCLO,CBLN1,DOCK2,CD53,SCIN,UNC13B,PDZD8,SLC22A17,REEP1,FABP6,ZDHHC6,BCL6,ZDHHC23,STEAP3,PROS1,GULP1,POU2F2,SCN2A,HSPA2,RPS13,GCA,PHLDB2,ANTXR2,TUBA1A,CSN2,NOP53,LRRC8B,SLC39A8,PTPN6,ACO1,CHRNA6,SYNJ2BP,RARRES2,FRK,RANBP2,IFT81,PTPRJ,KPNA3,BACH2,KCNG1,ITGA2,HGF,DISP1,SEPT5,SLC6A9,LRP4,TNFSF13B,GABRG2,SELL,IGF2BP2,HBE1,SFXN3,ARHGAP44,MCU,RPL34,RAB11FIP5,SLC35F1,KCNJ4,MAP1A,SCN1B,PRKCD,EHD3,KCNMB3,SGK1,MARCH3,TRIM3,IPCEF1,SYK,SLC45A3,ATP2B1,PCSK6,RIN2,RAB3B,CYTH3,SYBU,ASAP3,GRID1,PRICKLE1,MEI1,AGAP2,PHACTR2,TLR6,LEPR,ILDR2,HOMER3,MAP1B,RERE,DOCK7,ICA1,MFSD9,PRCP,SLC7A5,SLC18B1,DLG2,RPL4,SLC22A15,RPS12,GEM,SLC1A5,TBC1D4,KIF1B,SLC16A10,CACNA2D1,ABCG1,SNPH,STOM |
| 1.637e-04 | -8.72 | V$CDX2_Q5 | MSigDB lists | V$CDX2_Q5 | 233 | 41 | 17377 | 1707 |
INPPL1,PLSCR4,TRIM2,CHCHD7,PLAG1,CREB5,NRXN1,IKZF2,HECTD2,NEO1,PCDH7,NKX6-1,ATXN7L1,ZNF362,KCTD15,LHX6,TSC22D1,MARCH3,RIMS2,POU3F3,MN1,NDUFA4L2,RAX,MEIS2,PNRC1,NR6A1,DCHS1,VLDLR,PRDM1,CTTNBP2NL,SNAP25,ZFPM2,MBNL2,LEPR,BACH2,DLG2,PPARGC1A,NRP1,TNFRSF17,MLLT3,FRMD5 |
| 1.659e-04 | -8.70 | AKT_UP_MTOR_DN.V1_DN | MSigDB lists | AKT_UP_MTOR_DN.V1_DN | 174 | 33 | 17377 | 1707 |
PLA2G4A,MOCOS,ITGA6,BLVRB,ASS1,CBS,KCTD12,IL13RA1,ISYNA1,TNFRSF19,SATB1,SLCO3A1,PHLDA2,GAS1,FKBP11,EFEMP1,RTN1,TYMP,CHN2,CHRDL1,EIF4E3,MSX1,CAP2,MGAT4B,SMARCD3,CBY1,C1R,CDC42BPA,STEAP1,BEX4,FBN1,SLC7A5,HPGD |
| 1.674e-04 | -8.70 | regulation of heart contraction | biological process | GO:0008016 | 246 | 42 | 17256 | 1658 |
SCN5A,CACNG3,FGF13,BVES,CYP2J2,PKP2,ITPR2,CACNB4,NOS1AP,KCNJ4,IRX5,KCNN2,SCN1B,CACNB2,EHD3,DSG2,SREBF1,TRPC1,PDE4D,ATP2B1,NOS3,TRPM4,KCNIP3,GSTM2,TMEM65,ANK2,RYR2,GSTO1,KCND3,ATP1B1,DSP,ASPH,GJC1,KCNK15,GNAO1,APELA,ADRB1,TPM1,SEMA3A,CACNA2D1,ATP2B4,ATP1A3 |
| 1.680e-04 | -8.69 | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | 196 | 36 | 17377 | 1707 |
ARHGAP26,DMXL2,LGALS3,FLVCR2,PSTPIP2,HEBP1,ZCCHC24,BLVRB,LILRB1,KCTD12,CEBPA,CTBP2,SLCO3A1,ARHGEF10L,EPB41L3,PTPRE,CYP1B1,TBC1D8,RIN2,MICAL2,QSOX1,ALDH2,SLC36A1,MPP1,MAFB,TBC1D2,CEBPB,HPSE,NACC2,HK2,RAB31,TNFRSF1A,KIAA0513,HK1,RNF130,RRAGD |
| 1.689e-04 | -8.69 | positive regulation of phosphorylation | biological process | GO:0042327 | 1033 | 134 | 17256 | 1658 |
ACSL1,ACVR1,FGF13,PRKCA,SNX9,STK24,GSDME,RAP2A,ITGB3,EPHB6,TLR4,PRKACB,RASGRP1,PDGFRB,TNK2,GCNT2,TGFA,LRRK2,PRKAR2B,ACVR2B,ROR1,INHBC,GPRC5B,NCKAP1L,ERN1,TNFRSF1A,DIRAS1,NRP1,CACUL1,PRKAA2,TYRO3,ITGA6,SLK,SORBS3,TNFRSF10C,PFN2,TNFRSF19,IGF1R,ADCY6,INAVA,HMGCR,PAK1,FGFR4,MSTN,VLDLR,DUSP9,WWC1,STRADB,PDE8A,PLCB1,MAPKAPK2,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,EPHA3,AVPI1,NEK10,IL15,NTRK3,LCP2,TNKS1BP1,DDR1,PIBF1,PPP1R9A,TLR3,ACVR2A,DAB2IP,MET,HSPA2,IGFBP3,FZD1,PFKFB2,FZD4,ADCY1,WNT11,RARRES2,CD40,FGFR1,SNCA,NRG3,APELA,DUSP19,MAP3K21,HGF,TNFSF15,BMPR1A,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,LRP4,P2RY1,GAS6,EPHB1,PKN1,TPD52L1,BMP6,GHR,PRKCD,AFAP1L2,IQGAP3,TNFRSF11A,SPRY2,SYK,PARP9,PFKFB4,VEGFC,MOB1B,VAV3,RAPGEF2,GAREM1,AGAP2,RACK1,TLR6,DKK1,GPR37,PTPRC,FGR,DOCK7,MAP2K6,LRRK1,BMP4,MAP3K20,ATP2B4 |
| 1.690e-04 | -8.69 | regulation of locomotion | biological process | GO:0040012 | 979 | 128 | 17256 | 1658 |
ACVR1,RECK,ATP8A1,GATA3,PRKCA,ABHD6,STK24,F3,RND2,TCAF2,RAP2A,ITGB3,SLIT2,PDGFRB,NKX2-1,CYP1B1,GCNT2,ACVR1C,LRRK2,NCKAP1L,CCBE1,PLK2,SEMA3C,INPP5F,TPM1,NRP1,PPARGC1A,TMEFF2,MAGI2,SPOCK3,FRMD5,MEF2C,CHMP4C,EFNB2,FN1,LGALS3,RHOBTB1,BVES,ITGA6,SLK,PFN2,MTUS1,SEMA4F,IGF1R,GATA2,SRGAP1,PRKG1,NOS3,EPB41L5,PAK1,UNC5C,MID2,SPATA13,PLCB1,BEX4,RIPOR2,THBS4,CSF1,SEMA3A,SHTN1,NBL1,BTC,ZSWIM5,AMOTL1,RHOD,DOCK1,PLXNA2,COL18A1,NTRK3,SEMA6A,DAB2IP,MET,SNAI2,DOCK8,IGFBP3,PHLDB2,FER,EVL,PTPRU,PREX1,WNT11,RARRES2,SYNJ2BP,CD40,DOCK5,JAM3,FGFR1,SNCA,SMAD3,IRS2,CXCL10,PTPRJ,NRG3,APELA,LAMB1,ABI3,ITGA2,HGF,BMPR1A,HACE1,ROBO2,BMPR2,GAS6,PKN1,PHLDA2,NKX6-1,SGK3,SGK1,RRAS2,SPRY2,FES,VEGFC,RAPGEF2,MPP1,RACK1,GPLD1,PTPRC,DOCK7,FGR,MYADM,GCSAM,TERT,RND3,AKT3,PRCP,XBP1,MCC,BMP4 |
| 1.693e-04 | -8.68 | acetylgalactosaminyltransferase activity | molecular function | GO:0008376 | 49 | 14 | 17224 | 1680 |
CHSY3,GALNT3,GBGT1,GALNT1,B3GALT1,GALNT6,GALNT12,B3GALT2,GALNT13,GALNT17,CHSY1,B4GALNT3,GALNT18,GALNT14 |
| 1.699e-04 | -8.68 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN | 167 | 32 | 17377 | 1707 |
LATS2,RASAL2,IGFBP6,ATP8A1,MYO1B,RASL11B,GAS6,GAS1,PPP2R3A,PCDHB14,FKBP9,FBXO32,CNKSR3,EIF1,SGK1,WWC2,AGL,PRKACB,SNX7,ATF3,TNS1,JAM3,GNAI1,ID3,RND3,CECR2,B3GALT2,PAM,MAGI2,PURG,LIFR,CACNA2D1 |
| 1.707e-04 | -8.68 | secondary alcohol biosynthetic process | biological process | GO:1902653 | 44 | 13 | 17256 | 1658 |
PRKAA2,CYP51A1,IDI1,MVK,HMGCS1,ERG28,INSIG1,MSMO1,MVD,DHCR24,SQLE,DHCR7,HMGCR |
| 1.722e-04 | -8.67 | GO_POSITIVE_REGULATION_OF_ION_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_ION_TRANSPORT | 226 | 40 | 17377 | 1707 |
SCN5A,LGALS3,AKAP5,ATP8A1,VAMP8,PKP2,ABAT,P2RY1,NOS1AP,SCN1B,AKAP7,CNKSR3,CACNB2,PRKCD,PRELID1,SGK3,SGK1,TRPC1,TNFRSF11A,HSPA2,PDGFRB,RAB3B,GSTM2,ANK2,FGF12,RYR2,GSTO1,ATP1B1,AMIGO1,SGK2,ASPH,SNCA,CXCL10,WFS1,MAP2K6,BMP4,TRPC3,TESC,CACNA2D1,CNTN1 |
| 1.722e-04 | -8.67 | V$BRN2_01 | MSigDB lists | V$BRN2_01 | 226 | 40 | 17377 | 1707 |
PCDH18,INPPL1,FGF13,MYO1B,CREB5,FOXG1,SLCO3A1,PHLDA2,MECOM,FOXP2,CHN2,TACC2,FLRT3,HS3ST5,SGK3,NDUFB8,MYO3B,PRICKLE2,TSPAN13,IQGAP3,PTPRCAP,MYT1,C15orf41,GPM6A,ESRRG,NFIA,SNAP25,MBNL2,BCL11A,KLF12,NCAM2,KIAA0355,GNAO1,TUFT1,SPRY4,HOXB9,NR3C2,MMP16,CTNND2,ACSM3 |
| 1.731e-04 | -8.66 | GSE25087_FETAL_VS_ADULT_TREG_DN | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_DN | 160 | 31 | 17377 | 1707 |
C2orf88,ENO2,FZD4,AASS,KIF5A,UBASH3B,BACE1,RPL21,OPHN1,LITAF,ADCY1,NFIA,MORC4,RNF125,KIF5C,SYNJ2BP,FKBP11,IRS2,TMEM154,SLC22A17,KLF12,PAIP2B,ERN1,RUNDC3B,ACVR2A,KIF21A,KLF9,ZFP36L2,DCBLD1,ACSM3,ABCG1 |
| 1.731e-04 | -8.66 | CAIRO_LIVER_DEVELOPMENT_UP | MSigDB lists | CAIRO_LIVER_DEVELOPMENT_UP | 160 | 31 | 17377 | 1707 |
EFNB2,EVL,FGF13,RECK,WLS,SMARCD3,IGF2BP2,CTBP2,HBE1,TMEM47,FAM174B,SATB1,PFN2,FGFR1,GAS1,NEO1,GJC1,PLS3,TRPS1,ID3,KCTD15,PLOD2,FLRT3,AKT3,PLK2,PTPRS,PCOLCE2,SERPINH1,SEMA3A,CSRP2,LRP12 |
| 1.731e-04 | -8.66 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | 160 | 31 | 17377 | 1707 |
RPS20,EML5,CD55,PDK1,ACVR1C,MPP1,ITGA6,PPFIBP2,TCEA3,NUAK2,ZDHHC15,ADD2,NDRG2,BTBD9,AMIGO1,ARHGAP32,PRKCA,CENPV,SYDE2,RPL34,CACHD1,RIMKLB,RALGPS2,KLF12,MPP7,SVIL,ZBTB20,IPCEF1,WWC2,APBA2,RNF157 |
| 1.737e-04 | -8.66 | NRL_DN.V1_DN | MSigDB lists | NRL_DN.V1_DN | 125 | 26 | 17377 | 1707 |
QSOX1,INPPL1,ALDH2,PNP,NR4A1,PTPN13,RGS20,KIF5C,WWC1,PRKCQ,PRDM1,CRYBG3,JAM3,IL17D,FKBP9,PLEKHH2,PIK3AP1,RASGRF2,ADRB1,TUFT1,TMED9,MOXD1,TC2N,SMPDL3A,CTH,HRASLS |
| 1.742e-04 | -8.66 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP | 189 | 35 | 17377 | 1707 |
UGT8,RHOBTB1,GPR65,ST6GAL1,PTPN21,DHCR24,SETBP1,TJP1,KIF21B,ASNS,KMO,PRKCD,SP140,KLF9,ST8SIA1,TBC1D9,AGL,RASGRP1,ATP2B1,GLDC,FER,BCL7A,VNN2,GPM6A,SLC27A2,TES,PTPN6,LRMP,CR2,ROR1,ENTPD1,KIAA0355,RGS10,TNFRSF17,PKIA |
| 1.742e-04 | -8.66 | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN | MSigDB lists | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN | 189 | 35 | 17377 | 1707 |
CXCR5,ARHGAP26,CCDC126,LANCL3,PRSS12,JDP2,SCN8A,KIF5C,CHSY1,PFN2,IL18R1,BAG3,TLR3,ASNS,GPR155,PROS1,CERS4,ATP2B1,SMPDL3A,EPB41L5,TMEM65,PTPN13,MEF2B,AIG1,PDE8A,TEX9,SMPDL3B,ENPP1,IFT81,MYADM,PLAGL1,ERN1,PCGF2,NRP1,RNF157 |
| 1.742e-04 | -8.66 | GSE29618_MONOCYTE_VS_MDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_UP | 189 | 35 | 17377 | 1707 |
DMXL2,MXI1,ACSL1,IL15,LDLR,LILRB1,FAM198B,GRK6,SLCO3A1,ARHGEF10L,FRY,EIF1,LIN7A,MARCKS,TLR4,CKAP4,TBC1D8,GAB2,CYP1B1,VNN2,RIN2,WLS,MPP1,BNIP3L,MAFB,SMARCD3,NPC2,IRS2,CEBPB,FGR,HPSE,NACC2,KIAA0513,CLMN,SPRY4 |
| 1.742e-04 | -8.66 | LTE2_UP.V1_DN | MSigDB lists | LTE2_UP.V1_DN | 189 | 35 | 17377 | 1707 |
MOCOS,COL9A3,ID1,LGR4,HERC5,HERC6,CHN1,EFEMP1,PPM1E,IGF1R,SLC7A11,PMAIP1,KAZN,STC2,TFAP2A,GFRA1,LAMP3,PCSK6,GCA,MYO10,CAP2,FHL2,ATF3,PRKAR2B,SATB2,PLCB1,PDLIM3,MATN2,RAB31,SVIL,GRB10,INPP5F,GEM,NRP1,PTGES |
| 1.744e-04 | -8.65 | negative regulation of cellular process | biological process | GO:0048523 | 4646 | 509 | 17256 | 1658 |
THOC5,ACVR1,PPP4R4,DUSP8,LGR4,GRIK2,RECK,DNAJC3,LDLR,VAMP8,GATA3,NPM1,CTBP2,STAT5B,CEBPA,CHAC1,PRKCA,ABHD6,AARS,EYA4,STK24,TRPS1,SKI,TXNDC5,BAG3,PPP1R26,TGFBR3,IKZF5,ZFYVE28,RAP2A,CHRDL1,PACSIN1,POU3F3,NKX2-1,MEIS2,ACVR1C,DCC,NR6A1,WISP3,LRRK2,NFIA,BNIP3L,DEPTOR,FEZ1,AGO4,PRKAR2B,ACVR2B,SAV1,GNAI1,PYCR1,AHRR,ENPP1,SH3RF1,NCKAP1L,PLK2,ARHGAP28,ZBTB20,CAB39L,SEMA3C,SERPINI1,TMOD2,ERCC5,INPP5F,SPRY4,TPM1,NRP1,UNC5B,TMEFF2,SPART,LZTS1,SPOCK3,MEF2C,EFNB2,LATS2,KLF8,INPPL1,ZHX3,GABRB2,ITGA6,MLF1,DHCR24,OPHN1,SLC25A27,TNFRSF10C,FOXG1,CHD5,GAS1,RPL13A,MECOM,SYCP2,BNIP1,CNTN4,FRY,PAIP2B,BACE2,MYC,FLRT3,C1QL4,PRELID1,SREBF1,SRGAP1,PRKG1,JAM2,GLIS1,STXBP1,ZNF385A,GPR161,RNF152,BOD1,HMGCR,EPB41L5,PTCH2,RPL26,BDNF,QSOX1,VLDLR,ARID5B,FHL2,PACSIN3,RYR2,NSD2,SHISA2,PLCB1,CPEB1,BEX4,PLEKHH2,SH3GL2,PMEPA1,CLMN,SFMBT1,LAPTM4B,CDH2,SMYD3,EPHA3,TFCP2L1,NBL1,BTC,DNM3,PCSK1N,RASAL2,TMSB15A,C4A,RGS20,PLXNA2,PKP2,ADD2,TMEM170B,DDR1,TBC1D30,SPEG,PLPP1,ASNS,TLR3,DACT1,CNKSR3,MAGEA3,DAB2IP,PDE4D,SERPINH1,ZNF365,DOCK8,FZD1,GAPDH,FZD4,NKX3-2,SHANK2,PREX1,NLGN4X,ATF3,SATB2,CBY1,WNT11,PRKCQ,ATOH1,ASPH,FGFR1,SNCA,DCBLD2,IRS2,CXCL10,PRKCB,BEX3,WFS1,PEMT,WWTR1,ASIC1,MAP3K21,HPGD,KLF5,GRB10,BMPR1A,ATG5,MID1,KCTD1,MYO1D,FARP1,MXI1,C1QTNF3,ROBO2,IGFBP6,CKAP2,FZD8,EPS8,IPO5,UBAC2,GAS6,P2RY1,PKN1,EPHB1,ZNF219,RGS7,GDPD5,NEDD4,HOPX,RGS17,PCBP4,BHLHA15,SGK3,FIG4,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,ZFP36L2,PARP9,TRPM4,VEGFC,SLC40A1,BCL7A,GSTM2,RAPGEF2,RASA3,RACK1,GPLD1,CEBPB,PTPRC,TRIB3,ID3,NSD1,TERT,AKT3,XBP1,MCC,PCGF2,NEK11,BMP4,LRRK1,CERS1,SHOX2,B4GALT7,DDIT3,ATP2B4,FOXA1,BTRC,LARP1,TPT1,PHC1,PHACTR3,FGF13,TNFAIP8L2,LMCD1,LILRB1,ASS1,NDRG2,HDGFL3,ITPR2,ABAT,IKZF2,KREMEN1,GSDME,TUBB4A,EPCAM,PPM1E,RPS6KA2,KCNAB1,EOMES,ITGB3,EPHB6,CTTN,PTPRE,TLR4,ENO1,FANK1,SLIT2,PRKACB,PDGFRB,LAMP3,CYP1B1,CD55,KCNIP3,ATF4,GCNT2,SESN2,SKAP2,COL4A3,SPOCD1,YAP1,ROR1,PLEKHA1,TCERG1L,SESN1,SERGEF,TSKU,TRIM9,GSN,INSIG1,KLF12,ERN1,NCOA7,C8orf88,CIART,DLX2,PPARGC1A,TNFSF4,MAGI2,MLLT3,FRMD5,CHMP4C,RRAGD,BCL11B,PRKAA2,TYRO3,RGS16,RUNX2,FN1,LGALS3,STXBP5L,FBXO4,STXBP6,UBASH3B,JDP2,RASL11B,CHADL,SORBS3,ZIC2,SATB1,SPINK5,PFN2,FHOD3,DDIT4,EFEMP1,ZBTB38,ZNF354A,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,LRP6,ADCY6,BNIP3,BARX1,NOS3,PAK1,FGFR4,GPR176,ATP5IF1,MSTN,DUSP9,WWC1,STRADB,MAFB,PDE8A,PRDM1,HERPUD1,MAPKAPK2,RIPOR2,PLAGL1,HEYL,SH3BP4,HK2,EGFL7,NKX2-8,SEMA3A,TESC,SIX2,SFN,PRKN,ID1,IL15,RBFOX2,COL18A1,BCL6B,NTRK3,PIBF1,TNKS1BP1,PPP1R9A,CBLN1,SEMA6A,CYP26A1,SCIN,RIDA,SETDB2,CDC14B,FABP6,BCL6,FHIT,PROS1,WWC2,MET,ZNF488,HSPA2,SNAI2,GLI1,CTH,RPS13,IGFBP3,INTU,FER,PHLDB2,PRAME,EVL,TMEM67,CSN2,NOP53,PTPRU,PRDM13,PTPN6,TES,RNF125,VIM,GSTO1,SYNJ2BP,FRK,C4BPB,BCL11A,BATF3,WARS,CAMK2N1,SMAD3,MSC,ZNF93,NRG3,PTPRJ,BACH2,GBP1,RBPMS2,EIF4EBP1,RGS10,DUSP19,PTPRS,HGF,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,NECAB2,BMPR2,GRB14,PAK5,REL,APBB1,LRP4,SSX1,SLX1B,IGF2BP2,RASD1,NOTUM,OVOL2,USP30,BMP6,ARHGAP44,NKX6-1,RAB11FIP5,FOXP2,MAP1A,PRKCD,RASD2,KIAA0319,TFAP2A,KLF9,DUSP1,USP2,MSX1,KDM5B,CRIM1,NR4A1,FOXN3,NUGGC,LITAF,NUAK2,PRICKLE1,AGAP2,PHACTR2,ZFPM2,TLR6,LEPR,MGMT,SMPDL3B,RERE,DKK1,GPR37,DDAH1,MYADM,NACC2,GCSAM,FBN1,ACER2,MAP2K6,CTSV,DLG2,PAX9,TBC1D4,PTGES,MAP3K20,PKIA,ABCG1 |
| 1.773e-04 | -8.64 | GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 139 | 28 | 17377 | 1707 |
SEMA6B,DNM3,EVL,ID1,FGF13,DCC,RAPGEF2,LRP4,VIM,NRXN1,PFN2,SEMA6A,TBC1D30,BCL11A,EFEMP1,SEMA4F,PLK2,PRKCD,KIAA0319,ADCY6,SEMA3C,INPP5F,NRP1,GFI1,SEMA3A,SPRY2,SLIT2,SEMA6C |
| 1.801e-04 | -8.62 | V$IPF1_Q4 | MSigDB lists | V$IPF1_Q4 | 234 | 41 | 17377 | 1707 |
EXPH5,TYRO3,INPPL1,ZHX3,RHOBTB1,DOCK1,OTX1,PLXNA2,RNF24,PRDM8,SP8,PPP2R3A,NEO1,EFEMP1,ZNF827,SAMD11,BCL6,HRK,BEND4,EPHB6,FES,RAX,BDNF,SESN2,MEIS2,FOXN3,PRDM1,BAIAP2,ZIC1,GNAI1,BCL11A,SLC39A14,CACHD1,BACH2,PMEPA1,PELI2,BMP4,NRP1,FRMD5,CTNND2,MEF2C |
| 1.801e-04 | -8.62 | KRAS.DF.V1_UP | MSigDB lists | KRAS.DF.V1_UP | 182 | 34 | 17377 | 1707 |
BMPR2,SEC24D,ATP9A,GALNT6,HERC5,BBS9,BMP6,QPRT,RGS17,CPVL,CHRNA5,ALDOC,FLRT3,FAM168A,SMTN,BCL6,TRPC1,FAR2,HSPA2,SPRY2,TBC1D8,VEGFC,OPLAH,SMARCD3,ASPH,STEAP1,DKK1,ISG20,BEX4,AKT3,INPP4B,INPP5F,NRP1,SMYD3 |
| 1.801e-04 | -8.62 | V$GATA_Q6 | MSigDB lists | V$GATA_Q6 | 182 | 34 | 17377 | 1707 |
ENO2,CHCHD7,PLAG1,TNFSF13B,CREB5,ZNF219,BMP6,PPP2R3A,TRPS1,FOXP2,PPM1E,GPR155,LHX6,HS3ST5,TSPAN12,IPCEF1,TSPAN9,C15orf41,GATM,TNK2,COL4A3,SLITRK2,ESRRG,KCNH5,COL4A4,JPH1,FHL2,WNT11,HOXA1,KLF12,B3GALT2,SPRY4,PPARGC1A,STON2 |
| 1.801e-04 | -8.62 | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN | 182 | 34 | 17377 | 1707 |
PRKAA2,MRC2,RASAL2,TSPAN15,MSR1,SORBS3,HBE1,P2RY1,KIF21B,NRXN1,FAM174B,SATB1,PCLO,GAS1,CHN1,TLR3,DLX6,FAM168A,MID2,MICAL2,PXN,KLHL23,KLHL3,EXOC6B,PTPN13,DCHS1,EFHC2,TTC22,TNS1,GABARAPL1,MMP15,ITGA2,KIF1B,MLLT3 |
| 1.801e-04 | -8.62 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_UP | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_UP | 182 | 34 | 17377 | 1707 |
MXI1,AVPI1,LGALS3,BACE1,EPS8,TNFSF13B,SORBS3,CEBPA,CHN2,RPS6KA2,CPVL,GAS2L3,SGK1,TNFRSF11A,ZFP36L2,RNF170,MPP1,GDPD1,DEPTOR,AIG1,ATP1B1,RAB38,FNDC3A,SESN1,PLCB1,HERPUD1,C11orf45,TBC1D2,TPK1,SRD5A3,NCOA7,HGF,DBP,MEF2C |
| 1.801e-04 | -8.62 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_UP | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_UP | 182 | 34 | 17377 | 1707 |
ARHGAP26,AVPI1,FN1,RASAL2,TBC1D1,LPCAT2,UBASH3B,TMEM170B,SLC1A3,ABHD6,TRPS1,ACVR2A,KLF9,PJA1,NCEH1,ERRFI1,SPRY2,IL1RAP,PFKFB4,GAPDH,SKAP2,SPOCD1,MPP1,LRRK2,DHX32,HOMER3,GABARAPL1,PRCP,PLXDC2,SRD5A3,KIAA0513,SQLE,DISP1,DIRC2 |
| 1.819e-04 | -8.61 | regulation of cell motility | biological process | GO:2000145 | 909 | 120 | 17256 | 1658 |
BTC,NBL1,AMOTL1,ACVR1,DOCK1,RHOD,RECK,ATP8A1,PLXNA2,COL18A1,GATA3,NTRK3,PRKCA,ABHD6,SEMA6A,STK24,F3,RND2,TCAF2,RAP2A,ITGB3,DAB2IP,MET,SLIT2,DOCK8,SNAI2,PDGFRB,IGFBP3,NKX2-1,CYP1B1,FER,PHLDB2,EVL,GCNT2,ACVR1C,PTPRU,PREX1,WNT11,RARRES2,SYNJ2BP,CD40,DOCK5,JAM3,FGFR1,IRS2,SMAD3,CXCL10,NRG3,PTPRJ,NCKAP1L,CCBE1,PLK2,APELA,ITGA2,ABI3,LAMB1,HGF,SEMA3C,INPP5F,BMPR1A,TPM1,NRP1,PPARGC1A,TMEFF2,MAGI2,SPOCK3,FRMD5,MEF2C,HACE1,FN1,BMPR2,LGALS3,RHOBTB1,ITGA6,SLK,GAS6,PKN1,PFN2,PHLDA2,MTUS1,NKX6-1,SEMA4F,IGF1R,GATA2,SRGAP1,SGK3,PRKG1,SGK1,RRAS2,SPRY2,FES,NOS3,EPB41L5,PAK1,VEGFC,UNC5C,MPP1,RAPGEF2,SPATA13,RACK1,PLCB1,GPLD1,BEX4,PTPRC,FGR,DOCK7,MYADM,RIPOR2,RND3,TERT,GCSAM,THBS4,PRCP,CSF1,AKT3,XBP1,MCC,BMP4,SEMA3A,SHTN1 |
| 1.823e-04 | -8.61 | GO_RESPONSE_TO_GROWTH_FACTOR | MSigDB lists | GO_RESPONSE_TO_GROWTH_FACTOR | 464 | 70 | 17377 | 1707 |
CGN,ACVR1,ID1,RBFOX2,GATA3,STAT5B,NTRK3,ZFYVE9,SKI,TGFBR3,CHRDL1,ACVR2A,DAB2IP,PDGFRB,SNAI2,FZD1,FER,GCNT2,MEIS2,SMAD9,FGF12,FEZ1,ACVR2B,KCND3,FGF17,FGFR1,SNCA,SMAD3,ERN1,BMP1,HPGD,HGF,BMPR1A,NRP1,PPARGC1A,MAGI2,MEF2C,RUNX2,BMPR2,FN1,ESRP1,LRP4,GAS6,P2RY1,BMP6,GAS1,DDIT4,EEF2,FLRT3,MYC,GTF2F2,ERRFI1,SMAD6,FGFR4,EPB41L5,MSX1,PXN,KDM5B,MSTN,NR4A1,RAPGEF2,FERMT2,RYR2,GALNT3,MAPKAPK2,FBN1,HEYL,XBP1,BMP4,PAX9 |
| 1.826e-04 | -8.61 | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_DN | 49 | 14 | 17377 | 1707 |
BDNF,COL6A2,ZCCHC24,CNKSR3,STRADB,GRB10,GULP1,RGS7,SEMA3A,TTC28,SHOX2,MMP16,MAP1B,PNMA2 |
| 1.835e-04 | -8.60 | focal adhesion | cellular component | GO:0005925 | 397 | 60 | 18223 | 1724 |
ARHGAP26,EFNB2,SORBS1,MRC2,ITGA6,ARHGAP22,ARL2,NPM1,ENAH,SORBS3,RPL13A,PPFIBP1,RPS11,FLRT3,ITGB3,EHD3,SCARF2,MARCKS,CTTN,TLN2,RRAS2,TSPAN9,FES,PDGFRB,FZD1,RPS13,EPB41L5,PAK1,PDLIM7,PHLDB2,SYNPO2,EVL,PXN,TES,CAPN5,ASAP3,FHL2,FERMT2,VIM,TNS1,PALLD,SNTB1,PEAK1,PTPRC,GSN,LMLN,DOCK7,RPL12,RND3,FAT1,PTK7,ITGA2,SVIL,RPL4,SPRY4,NRP1,CDH2,CSRP2,MME,LPP |
| 1.856e-04 | -8.59 | HOXA9_DN.V1_DN | MSigDB lists | HOXA9_DN.V1_DN | 175 | 33 | 17377 | 1707 |
FADS1,SERINC5,COL9A3,RGS16,PDK1,ZNF395,RNF144A,TES,MVD,MYO1B,EPS8,SLITRK5,CBS,SLC7A2,SAV1,TAF4B,TBC1D30,ZIC1,CYP51A1,TRIB3,TEX15,HMGCS1,KCTD15,PLAGL1,MSMO1,ALDOC,SREBF1,SQLE,GRB10,SLC1A5,DHCR7,SPRY2,HMGCR |
| 1.856e-04 | -8.59 | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_6H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_6H_UP | 175 | 33 | 17377 | 1707 |
ANO10,WDR17,ANKRD13D,CHCHD7,LILRB1,TBC1D30,DDIT4,PIK3AP1,PRKCD,SH3PXD2B,JAM2,KIAA1211,SMPDL3A,GLDC,VNN2,SESN2,FAM84A,TGFA,ESRRG,NFE2L1,PREX1,C3orf70,CA13,GLCE,HTR7,PLK2,ATP7B,EMILIN2,RAB31,HS3ST3B1,MBOAT2,PTGES,SLC16A10 |
| 1.865e-04 | -8.59 | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN | 197 | 36 | 17377 | 1707 |
ACSL1,LGALS3,FN1,IGFBP6,GALNT12,PPFIBP2,KCTD12,SCD,SLC1A3,RTN1,TYMP,NELL2,CHN2,CA2,KMO,TSC22D1,PTPRE,SYK,LRP12,CKAP4,CYP1B1,FADS1,ALDH2,RHOQ,DCHS1,ATP1B1,BEX4,GSN,NACC2,KIAA0355,SLC2A6,SEMA3C,RNF130,DBP,NRP1,RRAGD |
| 1.871e-04 | -8.58 | GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT | MSigDB lists | GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT | 448 | 68 | 17377 | 1707 |
EXPH5,DOC2A,PLA2G4A,SYT12,C4A,VAMP8,LILRB1,SYT14,DOCK2,PCLO,TBC1D30,NCS1,ADPRHL1,UNC13B,RAB26,PROS1,PACSIN1,RAB27B,GAB2,TBC1D8,TNK2,FER,DNAJC6,LRRK2,SYNJ2BP,TBC1D16,C4BPB,SNCA,TRIM9,INSIG1,NCKAP1L,ITGA2,INPP5F,NRP1,SEPT5,MAGI2,STON2,TC2N,LGALS3,STXBP5L,TBC1D1,BVES,STXBP6,OPHN1,BTBD9,GAS6,PFN2,GAS1,GATA2,LMAN2,CADPS2,TBC1D9,STXBP1,SYK,FES,RIMS2,RAB3B,TBC1D8B,RAPGEF4,PACSIN3,HIP1,PLCB1,DKK1,TBC1D2,FGR,SH3GL2,PLD1,TBC1D4 |
| 1.873e-04 | -8.58 | V$LEF1_Q6 | MSigDB lists | V$LEF1_Q6 | 242 | 42 | 17377 | 1707 |
CGN,SORBS1,GABRB2,KIF5A,GABRG2,COL18A1,DOCK3,TNFRSF19,SP8,TUBB4A,FOXP2,CHN2,IGF1R,LRRN1,PCBP4,MCF2L,MPPED2,SHF,PDE4D,THSD1,PAK1,TUBA1A,NR6A1,PRDM13,CRIP2,PACSIN3,MAFB,SLC25A28,FGF17,RNF44,STEAP1,PTPRJ,MAP2K6,SLCO5A1,SPRY4,CERS1,FNBP1L,LIFR,PANK3,FOXA1,CACNA2D1,PHC1 |
| 1.874e-04 | -8.58 | positive regulation of actin filament bundle assembly | biological process | GO:0032233 | 56 | 15 | 17256 | 1658 |
PAK1,SMAD3,ARHGEF10L,PPM1E,SYNPO2,EVL,PXN,ID1,GPR65,SORBS3,WNT11,SH3PXD2B,TPM1,NRP1,PFN2 |
| 1.896e-04 | -8.57 | response to growth factor | biological process | GO:0070848 | 517 | 75 | 17256 | 1658 |
CGN,ID1,ACVR1,RBFOX2,GATA3,NTRK3,STAT5B,ZFYVE9,SKI,TGFBR3,CHRDL1,ACVR2A,DAB2IP,SNAI2,PDGFRB,FER,GCNT2,MEIS2,SMAD9,FGF12,FEZ1,FGF17,ACVR2B,FGFR1,SNCA,SMAD3,ERN1,HPGD,HGF,BMPR1A,NRP1,PPARGC1A,MAGI2,MEF2C,RUNX2,BMPR2,ESRP1,LRP4,P2RY1,GAS6,BMP6,GAS1,DDIT4,EEF2,MYC,FLRT3,GTF2F2,ERRFI1,SMAD6,ZFP36L2,FGFR4,EPB41L5,BDNF,MSX1,PXN,KDM5B,MSTN,NR4A1,RAPGEF2,RYR2,FERMT2,PDE8A,GAREM1,MARS,RACK1,BAIAP2,MAPKAPK2,GALNT3,FAT4,SH3GL2,FBN1,HEYL,PAX9,BMP4,KIF1B |
| 1.897e-04 | -8.57 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_DN | 23 | 9 | 17377 | 1707 |
GPT2,TRIB3,RAB3B,PLAGL1,VLDLR,SGK3,MORC4,DACH2,NEO1 |
| 1.905e-04 | -8.57 | GSE29618_BCELL_VS_MONOCYTE_UP | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_UP | 168 | 32 | 17377 | 1707 |
CXCR5,RPS20,BCL7A,KLF8,EVL,COL4A3,CKAP2,ATP8A1,ST6GAL1,ARID5B,COBLL1,ADD2,SEL1L3,BCL11A,ISG20,CD37,ABLIM1,ZNF93,BACH2,BACE2,MYC,PIK3C2B,TSPAN13,SP140,RPS12,PTPRCAP,RRAS2,RASGRP1,PRKACB,RPS23,RAB30,DENND5B |
| 1.917e-04 | -8.56 | TTGCCAA,MIR-182 | MSigDB lists | TTGCCAA,MIR-182 | 304 | 50 | 17377 | 1707 |
EFNB2,PCDH18,STOX2,ACVR1,RHOBTB1,ABHD13,NPM1,CEBPA,CADM2,EPHB1,KIAA1217,CCNJ,RGS17,PPM1E,ABLIM1,AKAP7,ADCY6,MARCKS,CTTN,TSPAN9,NTNG1,PRKACB,IGSF3,MOB1B,BDNF,MEIS2,SKAP2,RAB6B,FOXN3,ANK2,VLDLR,SATB2,PRDM1,TMEM47,PALLD,RNF44,MBNL2,BCL11A,MYADM,KPNA3,INSIG1,BACH2,XBP1,SH3BP4,SPRY4,PLD1,FNBP1L,MMP16,MEF2C,DOCK9 |
| 1.919e-04 | -8.56 | GO_REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_HYDROLASE_ACTIVITY | 1272 | 163 | 17377 | 1707 |
ARHGAP26,PPP4R4,RECK,NPM1,DOCK3,FAM13A,SNX9,F3,ARHGEF10L,ADPRHL1,SIPA1L2,PPP1R26,PMAIP1,PCOLCE2,PPP2R2B,SLIT2,RAPGEF5,RASGRP1,PDGFRB,TBC1D8,LAMP3,TNK2,COL4A3,ACVR1C,SPOCD1,LRRK2,ELMOD1,FGF17,SERGEF,ARHGEF26,GSN,NCKAP1L,SH3RF1,RASGRF2,ERN1,ADRB1,ARHGAP28,BBC3,SERPINI1,TPM1,MAGI2,SPOCK3,MEF2C,RGS16,FN1,STXBP5L,TBC1D1,BVES,ITGA6,DHCR24,OPHN1,SPINK5,PFN2,CHN1,RALGPS2,MYC,PRELID1,SRGAP1,PRKG1,NCAM1,DENND1C,GFRA1,NOS3,FGFR4,TBC1D8B,RAPGEF4,SPATA13,RYR2,OBSCN,HIP1,PLCB1,FAM162A,HERPUD1,TBC1D2,SH3BP4,PTPRN2,IQSEC2,FNBP1L,SFN,DOCK9,EPHA3,BTC,PCSK1N,RASAL2,DOCK1,GPR65,C4A,ARHGAP22,RGS20,NTRK3,DENND3,DOCK2,TBC1D30,TIAM2,TBC1D19,BCL6,DAB2IP,MARCKS,PROS1,SERPINH1,HSPA2,PERP,DOCK8,PREX1,WNT11,ATP1B1,CD40,DOCK5,TBC1D16,ASPH,FGFR1,SNCA,IRS2,SMAD3,ARHGAP21,ITGA2,RGS10,PLEKHG1,HGF,TNFSF15,DENND5B,MYO1D,FARP1,LPAR2,ARHGEF11,IPO5,ARL2,PSD3,GAS6,RGS7,PPP2R3A,ARHGAP44,SYDE2,RGS17,CHN2,MCF2L,PRKCD,RALGAPA2,IQGAP3,TBC1D9,ERRFI1,SPRY2,RIN2,VAV3,ARAP2,CRIM1,MCF2L2,RAPGEF2,CYTH3,ASAP3,RASA3,AGAP2,ARHGAP32,LEPR,MGMT,GPLD1,DOCK7,ACER2,GNAO1,GRIN2D,DLG2,TBC1D4,DOCK6 |
| 1.925e-04 | -8.56 | KORKOLA_YOLK_SAC_TUMOR | MSigDB lists | KORKOLA_YOLK_SAC_TUMOR | 55 | 15 | 17377 | 1707 |
MOK,PCDH10,EHHADH,EOMES,LRRN1,PTPN13,FLRT3,FRAS1,PLXNA2,C1R,SHISA2,CDH2,CEBPD,CYP26A1,PCDH7 |
| 1.934e-04 | -8.55 | SH3PXD2A (SH3 and PX domains 2A) | protein interactions | 9644 | 90 | 21 | 17029 | 1718 |
PRKAA2,CGN,PHLDB2,RASAL2,PRSS12,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,SH3BP4,SVIL,CTTN,TANC2,OSBPL6,KIF1B,LARP1,GAB2 |
| 1.938e-04 | -8.55 | GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN | 190 | 35 | 17377 | 1707 |
CXCR5,RGS16,DYRK3,ACSL1,ENO2,BMPR2,GRIK2,REL,DENND3,SPINK5,PCDH7,PAIP2B,MARCH3,VGLL4,ZNF460,SEMA6C,FGFR4,TNK2,GPM6A,DNAJC6,WWC1,ATF3,GSTO1,ATP1B1,PLCB1,HOXA1,GJC1,DCBLD2,ZIC1,ID3,LAPTM4B,GEM,SHOX2,MLLT3,MAST1 |
| 1.938e-04 | -8.55 | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP | MSigDB lists | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP | 190 | 35 | 17377 | 1707 |
INPPL1,REL,ST6GAL1,COBLL1,ADSSL1,DENND3,TSPAN17,RNF141,PPM1E,MGAT1,MARVELD2,PRKCD,BCL6,MARCKS,POU2F2,TLR4,CKAP4,PFKFB4,SH3BP2,PTPN6,CAPN5,NUAK2,CD40,ARHGAP21,FGR,HPSE,PRKCB,PRCP,EIF4EBP1,AKT3,SLC2A6,RAB31,SFMBT1,RNF157,DENND5B |
| 1.938e-04 | -8.55 | GSE7852_LN_VS_FAT_TREG_DN | MSigDB lists | GSE7852_LN_VS_FAT_TREG_DN | 190 | 35 | 17377 | 1707 |
PCDH18,INPPL1,RHOBTB1,JDP2,MLF1,CMTM8,YPEL2,COBLL1,SLCO3A1,BEX2,HOPX,TBC1D19,GALNT1,IDI1,FAM107B,NCEH1,DUSP1,FZD4,AGPAT4,RAPGEF2,PARD3B,MGAT4B,CRIP2,RNF125,PRKAR2B,MFSD6,SMAD3,CXCL10,ARHGAP21,GSN,HLF,INSIG1,CDH17,SQLE,CHMP4C |
| 1.939e-04 | -8.55 | GO_SYNAPSE_ASSEMBLY | MSigDB lists | GO_SYNAPSE_ASSEMBLY | 67 | 17 | 17377 | 1707 |
BDNF,GPM6A,FARP1,DNM3,PTPRD,LRP4,SHANK2,NLGN4X,SDK1,NRXN1,DNER,PCLO,PCDHB14,FLRT3,CDH2,MAGI2,FZD1 |
| 1.942e-04 | -8.55 | CBY1 (chibby family member 1, beta catenin antagonist) | protein interactions | 25776 | 150 | 30 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,PFKFB2,TBC1D1,PTPN13,PLEKHA5,KIF5C,LPIN3,FAM110B,SPIRE1,BAIAP2,NUMBL,ABLIM1,FKBP9,DOCK7,NAV1,RALGPS2,SH3BP4,GAN,MAP3K21,MAP7,DAB2IP,TANC2,OSBPL6,KIF1B,ZFP36L2,SFN,LARP1,GAB2 |
| 1.979e-04 | -8.53 | soft_tissue-striated_muscle-rhabdomyosarcoma | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma | 602 | 86 | 17385 | 1698 |
ARHGAP26,DMXL2,TRIM16,GRIK2,DNAJC3,HECW2,CTBP2,CHUK,RADIL,CCNJ,TRPS1,LGI2,SIPA1L2,NELL2,UNC13B,SEC16B,ALDH1L1,NBEA,JAKMIP2,SLC2A12,SCN2A,TLR4,NEB,CSN2,EML6,DCC,JPH1,NLGN4X,VIM,WNT11,SATB2,PLEKHA1,ZDHHC14,DSP,DOCK5,TSKU,ARMC4,PRKCB,PTK7,HGF,MAGI2,LZTS1,CTNND2,SCN5A,ALOX5AP,STXBP5L,BMPR2,KLHL13,ARHGEF11,CYP2J2,ESRP1,ARL2,TJP1,COL4A5,GALNT13,PFN2,TECPR1,IGF1R,SMTN,PRICKLE2,TSPAN13,PARP9,FGFR4,CDH26,SH2D2A,PTPN13,DCHS1,KIAA1324L,EFNA3,PRICKLE1,SLITRK5,RYR2,PRDM1,ZFPM2,TMEM74,FAT4,FBN1,ADAMTS3,PMEPA1,FAT1,PTPRN2,SLFN5,MMP16,XKR4,FOXA1,MME |
| 1.988e-04 | -8.52 | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | MSigDB lists | ALCALAY_AML_BY_NPM1_LOCALIZATION_UP | 126 | 26 | 17377 | 1707 |
ACVR1,CFH,SPATA6,ARHGAP22,BIK,PLS1,COL4A5,RAB38,ASPH,FAM110B,HOXA1,QPRT,EPB41L3,ICA1,HMGCS1,PPP1R26,UNC13B,MSMO1,GATA2,LAPTM4B,GSTM3,GRB10,TLR4,HOXB9,SNX10,SMPDL3A |
| 1.988e-04 | -8.52 | GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_UP | MSigDB lists | GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_UP | 126 | 26 | 17377 | 1707 |
WDR17,FGF13,DNAJC3,PLS1,NTRK3,RGS7,SGK2,IKZF2,PCLO,SMPDL3B,SCIN,PYCR1,TEX15,KCNMB4,SLC7A11,HPSE,ALDOC,MAPK13,SLC22A15,FAM155A,FANK1,NR3C2,LAMP3,LPP,CNTN1,SNPH |
| 1.994e-04 | -8.52 | BURTON_ADIPOGENESIS_1 | MSigDB lists | BURTON_ADIPOGENESIS_1 | 33 | 11 | 17377 | 1707 |
CEBPB,IRS2,ID3,BAG3,MYC,LITAF,TSC22D1,SGK1,DLX2,ERRFI1,CEBPD |
| 1.994e-04 | -8.52 | GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT | 33 | 11 | 17377 | 1707 |
SCN5A,SCN1B,CNKSR3,FGF12,SGK3,SGK1,PKP2,ATP1B1,SGK2,TESC,CNTN1 |
| 2.001e-04 | -8.52 | YANG_BCL3_TARGETS_UP | MSigDB lists | YANG_BCL3_TARGETS_UP | 344 | 55 | 17377 | 1707 |
EPHA3,TNIK,ACSL1,IGFBP6,AASS,CKAP2,SCD,HERC6,NEDD4,TBC1D19,EPB41L3,TGFBR3,RALGPS2,BACE2,RASD2,SGK3,LIMCH1,CERS4,TMEM37,TLN2,FIGN,JAM2,GATM,RAPGEF5,RASGRP1,RNF152,PFKFB4,CD55,PFKFB2,NR4A1,AGPAT4,PTPN6,VLDLR,SYBU,FASN,CALCRL,C1R,LDHD,ARHGEF26,BEX4,CXCL10,GNB4,MATN2,SERPINI1,TNFRSF17,PPARGC1A,TNFSF4,CMPK2,MBOAT2,LRRC27,OSBPL6,STON2,MME,SLC16A10,PCSK5 |
| 2.001e-04 | -8.52 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN | 86 | 20 | 17377 | 1707 |
VAV3,MYO1D,DCC,GALNT13,ATF3,PHLDA2,PYCR1,AHRR,GTSF1,SLC22A18,CDH17,COL19A1,TSPAN13,HOXD13,SEMA3C,PCOLCE2,FAM84B,LOXL4,NPTXR,PGBD5 |
| 2.006e-04 | -8.51 | atypical | COSMIC cancer mutations | atypical | 518 | 76 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,RASAL2,CHUK,NTRK3,GRK6,LPIN3,PRKCA,DDR1,IKZF2,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,SLC2A12,MET,PRKACB,PDGFRB,FER,TNK2,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ACVR2B,ROR1,SGK2,FRK,FGFR1,BCL11A,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,NRP1,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PKN1,EPHB1,COL27A1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,NUAK2,OBSCN,STRADB,CDC42BPA,MAPKAPK2,TRIB3,FGR,PKN3,TERT,AKT3,MAP2K6,UACA,NEK11 |
| 2.008e-04 | -8.51 | P53_DN.V1_DN | MSigDB lists | P53_DN.V1_DN | 183 | 34 | 17377 | 1707 |
PLA2G4A,ZNF516,RGS20,COLEC10,KBTBD11,DOCK2,SLC19A2,MTUS1,EPB41L3,CA2,CPVL,BCHE,SGK1,ACTA2,SLC6A15,ST8SIA1,FAM155B,HSPA2,GFRA1,GLDC,PRAME,RHOQ,TDRD3,NR4A1,PTPN13,STAT4,VLDLR,ADCY1,VIM,ABCC2,BEX4,GPRC5B,MYOM2,STOM |
| 2.008e-04 | -8.51 | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN | 183 | 34 | 17377 | 1707 |
PRKAA2,FGF13,ST14,UBASH3B,MSR1,KCTD12,OR51B4,SFXN3,DENND3,EPDR1,ZBTB38,IPCEF1,MED7,RNF148,GFI1,RASGRP1,PERP,VEGFC,RHOQ,SKAP2,AGPAT4,CCNG1,AMIGO1,ENTPD1,CAMK2N1,MYADM,FAT1,CSF1,CLDN12,KCNG1,ABI3,ADRB1,LRRK1,FILIP1 |
| 2.008e-04 | -8.51 | GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_UP | 183 | 34 | 17377 | 1707 |
FRMPD3,COL9A3,TTC39B,UBASH3B,ESRP1,GABRG2,ADAMTS6,NTRK3,SFXN3,SNX9,HOPX,CYP51A1,SIPA1L2,KCNAB1,NOVA2,BACE2,AFF2,TMEM86A,NAP1L3,MED7,NCEH1,TBC1D9,SLC45A3,MED12L,PCSK6,GLI1,CARD6,COL6A2,USP2,TBC1D2,GSTO2,WWTR1,SLCO5A1,ABCG1 |
| 2.008e-04 | -8.51 | GSE7460_TCONV_VS_TREG_LN_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_UP | 183 | 34 | 17377 | 1707 |
CARS,LANCL3,ZHX3,ELOVL7,LDLR,MCTP2,PSD3,CREB5,SATB1,KREMEN1,RNF150,TGFBR3,SEMA4F,SLC30A4,EHD3,ITGB3,MAP7,ADCY6,RAB27B,SSH3,PDK1,DCC,MYO10,RAPGEF4,RASA3,ATP1B1,MFSD6,HOXA1,GSN,C1orf21,RCN3,HS3ST3B1,SLC16A10,AMPD1 |
| 2.015e-04 | -8.51 | ear development | biological process | GO:0043583 | 202 | 36 | 17256 | 1658 |
CELSR1,GABRB2,MCOLN3,OTX1,SLC25A27,GATA3,CEBPA,NTRK3,DDR1,FOXG1,GSDME,PDZD7,GATA2,DLX6,TFAP2A,MYO3B,LIN7A,SPRY2,PDGFRB,MSX1,NKX3-2,DCHS1,MAFB,ATOH1,ROR1,HOXA1,FGFR1,ZIC1,MAPKAPK2,INSIG1,FAT4,PTK7,WDR19,BMP4,ATG5,SIX2 |
| 2.016e-04 | -8.51 | GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION | 289 | 48 | 17377 | 1707 |
EPHA3,DNM3,FN1,ROBO2,BMPR2,PTPRD,AKAP5,APBB1,NTRK3,PPP1R9A,RND2,EFEMP1,NUMBL,SCN1B,SGK1,DAB2IP,MARCKS,FIG4,PACSIN1,SLIT2,RIMS2,FES,BDNF,DISC1,GPM6A,RHOQ,RAPGEF2,VLDLR,FEZ1,PRKCQ,AMIGO1,FGFR1,CPEB1,BAIAP2,MAP1B,BCL11A,NEGR1,GPRC5B,PTK7,ITGA2,HGF,BMP4,NRP1,FNBP1L,SHOX2,MAGI2,COBL,CNTN1 |
| 2.026e-04 | -8.50 | GO_CELL_CELL_SIGNALING | MSigDB lists | GO_CELL_CELL_SIGNALING | 744 | 103 | 17377 | 1707 |
DOC2A,LGR4,FGF13,IL15,AKAP5,GRIK2,KIF5A,SYT12,GATA3,PKP2,SYT14,NRXN1,CACNB4,NOVA1,RAC3,CBLN1,PCLO,PPP1R9A,UNC13B,CHRNA5,PPFIA2,LIN7A,TSHR,GLI1,FZD1,FZD4,WISP3,WLS,GJB2,ANK2,LRRK2,FGF12,CHRNA6,ACVR2B,FGF17,FGFR1,SNCA,GJC1,HTR7,TRIM9,CXCL10,KCNMB4,RGS10,ADRB1,PTPRS,TMOD2,HGF,SEPT5,NRP1,APBA2,TC2N,MEF2C,PCSK5,EFNB2,SCN5A,LRFN5,SLC6A9,PTPRD,GABRB2,GABRG2,TJP1,GABRR2,SLC1A3,SLC12A6,APBA1,KCNC4,PCDHB14,RAB11FIP5,SEMA4F,SCN1B,CACNB2,BHLHA15,RASD2,KCNMB3,LRP6,CADPS2,STXBP1,TNFRSF11A,BARX1,RIMS2,CHRM3,DLGAP1,FADS1,GPR176,BDNF,KCNQ3,CACNA1E,RAPGEF4,EFNA3,SLITRK5,RYR2,SNAP25,PLCB1,ILDR2,GRIK4,FAT1,PTPRN2,GRIN2D,DLG2,BMP4,KIF1B,FOXA1,SNPH |
| 2.028e-04 | -8.50 | positive regulation of nitrogen compound metabolic process | biological process | GO:0051173 | 2965 | 338 | 17256 | 1658 |
THOC5,ACVR1,LGR4,DNAJC3,LDLR,GATA3,NPM1,CTBP2,STAT5B,CEBPA,PRKCA,SNX9,EYA4,STK24,NOS1AP,TRPS1,SKI,PMAIP1,FAM168A,RAP2A,TSHR,POU3F3,NKX2-1,MEIS2,SMAD9,ACVR1C,NR6A1,TGFA,LRRK2,NFIA,MEF2B,PRKAR2B,ACVR2B,F12,AHRR,HLF,NCKAP1L,CCBE1,PLK2,ADRB1,BBC3,DIRAS1,NRP1,MEF2C,ITGA6,SLK,TNFRSF10C,TNFRSF19,MECOM,APLF,MYC,PRELID1,SREBF1,GRIP1,GLIS1,PRR16,GPR161,HMGCR,RPL26,STAT4,VLDLR,FHL2,PACSIN3,NSD2,HIP1,SMARCD3,TAF4B,ARRDC4,PLCB1,FAM162A,PELI2,THBS4,INHBE,HOXD13,CDH2,SMYD3,EPHA3,ZNF516,RNF144A,OTX1,CHUK,LCP2,DDR1,TLR3,DACT1,DAB2IP,PERP,FZD1,FZD4,PFKFB2,SOX21,ADCY1,ATF3,SATB2,PRKCQ,WNT11,PXYLP1,PYGO1,ATOH1,ASPH,FGFR1,SNCA,ZNF711,CXCL10,IKZF3,BEX3,WFS1,APELA,PEMT,WWTR1,MAP3K21,TNFSF15,KLF5,BMPR1A,DBP,MAPK10,HOXB9,MID1,EDA2R,CKAP2,PLAG1,CD276,FZD8,GAS6,P2RY1,CREB5,PKN1,EPHB1,ZNF219,NDFIP2,TPD52L1,NEDD4,GSAP,KDM7A,BHLHA15,GHR,YBX3,MYO6,SMAD6,SPRY2,ZFP36L2,MED12L,PARP9,PFKFB4,VEGFC,SLC40A1,RAPGEF2,GAREM1,RACK1,GUCY1A2,SKAP1,HOXA1,ZIC1,GPLD1,CEBPB,PTPRC,TRIB3,NSD1,TERT,XBP1,BMP4,LRRK1,SHOX2,DDIT3,ATP2B4,FOXA1,LARP1,BTRC,ACSL1,TRIM16,FGF13,ASS1,LILRB1,ABAT,IKZF2,GSDME,F3,ARHGEF10L,EPCAM,EOMES,GRHL1,ITGB3,PCOLCE2,EPHB6,ENO1,FANK1,TLR4,ETV1,PDGFRB,RASGRP1,PRKACB,TNK2,ATF4,GCNT2,SESN2,COL4A3,NFE2L1,YAP1,ROR1,BATF,DYRK1B,INHBC,GSN,GPRC5B,INSIG1,ERN1,TNFRSF1A,NCOA7,DLX2,PPARGC1A,TNFSF4,MAGI2,CACUL1,MLLT3,BCL11B,PRKAA2,TYRO3,LONRF1,RUNX2,FN1,JDP2,FBXO4,SORBS3,ZIC2,PFN2,RNF180,ZBTB38,EEF2,IGF1R,GATA2,EBF4,LRP6,ADCY6,INAVA,BARX1,CAND2,CEBPD,NOS3,PAK1,FGFR4,RAX,ATP5IF1,RHOQ,MSTN,EFNA3,WWC1,STRADB,MAFB,DUSP9,PDE8A,HERPUD1,MAPKAPK2,PLAGL1,HEYL,CSF1,NKX2-8,SEMA3A,TESC,SIX2,CREB3L2,PRKN,AVPI1,NEK10,IL15,HECW2,NTRK3,LPIN3,TNKS1BP1,PIBF1,PPP1R9A,CDC14B,BCL6,ACVR2A,MET,POU2F2,HSPA2,GLI1,IGFBP3,ALG10B,NOP53,RNF125,VIM,RARRES2,CD40,C4BPB,SMAD3,NRG3,RNF217,ITGA2,DUSP19,SOHLH2,HGF,HEY1,CNTN1,TENM1,TNIK,NECAB2,BMPR2,ARHGEF11,PAK5,REL,APBB1,LRP4,SLX1B,OVOL2,BMP6,NKX6-1,PRKCD,RASD2,GTF2F2,TFAP2A,AFAP1L2,IQGAP3,TNFRSF11A,SYK,MICAL2,MSX1,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,PRICKLE1,MARS,ZFPM2,TLR6,MGMT,DKK1,RERE,EBF1,GPR37,DDAH1,DOCK7,ACER2,MAP2K6,MYRF,PAX9,MAP3K20 |
| 2.030e-04 | -8.50 | regulation of catalytic activity | biological process | GO:0050790 | 2299 | 269 | 17256 | 1658 |
ARHGAP26,PPP4R4,DUSP8,RECK,DNAJC3,NPM1,CEBPA,SNX9,STK24,NOS1AP,BAG3,PPP1R26,PMAIP1,ZFYVE28,SERINC2,PPP2R2B,RCAN3,TSHR,TBC1D8,ACVR1C,CAP2,TGFA,LRRK2,ELMOD1,DEPTOR,PRKAR2B,ACVR2B,SH3RF1,NCKAP1L,ADRB1,ARHGAP28,BBC3,SERPINI1,DIRAS1,SPRY4,TPM1,NRP1,SPOCK3,MEF2C,LATS2,ALOX5AP,TBC1D1,ITGA6,SLK,DHCR24,OPHN1,GPSM2,TNFRSF10C,DYNC1I1,GRPEL2,CHN1,FRY,MYC,FLRT3,PRELID1,SRGAP1,PRKG1,HMGCR,BOD1,TBC1D8B,VLDLR,RYR2,HIP1,ARRDC4,PLCB1,FAM162A,MMP15,SMYD3,DOCK9,EPHA3,PCSK1N,RASAL2,C4A,GPR65,PLXNA2,RGS20,LCP2,DDR1,TBC1D30,TIAM2,TLR3,MAGEA3,DAB2IP,SERPINH1,PERP,DOCK8,GAPDH,FZD4,PFKFB2,ADCY1,PREX1,PRKCQ,WNT11,ATP1B1,ASPH,TBC1D16,FGFR1,SNCA,IRS2,CXCL10,ARHGAP21,BEX3,WWTR1,MAP3K21,TNFSF15,MAPK10,SERINC5,MYO1D,FARP1,FZD8,IPO5,ARL2,HERC5,GAS6,PKN1,EPHB1,RGS7,TPD52L1,RGS17,GHR,RALGAPA2,ERRFI1,TBC1D9,GFI1,SPRY2,PARP9,VAV3,ARAP2,RAPGEF2,RASA3,RACK1,GPLD1,PTPRC,TRIB3,FGR,TERT,GNAO1,BMP4,CERS1,ATP2B4,PHACTR3,ACSL1,FGF13,FAM13A,F3,ADPRHL1,PPM1E,SIPA1L2,ITGB3,PCOLCE2,EPHB6,TLR4,SLIT2,PDGFRB,RASGRP1,PRKACB,LAMP3,TNK2,SESN2,COL4A3,SPOCD1,ROR1,GSN,GPRC5B,ERN1,MAGI2,CACUL1,PCSK5,TYRO3,RGS16,STXBP5L,FN1,BVES,UBASH3B,PFN2,SPINK5,RNF180,IGF1R,ADCY6,INAVA,LRP6,NOS3,FGFR4,PAK1,ATP5IF1,MSTN,GPSM1,EFNA3,STRADB,DUSP9,HERPUD1,TBC1D2,MAPKAPK2,ADGRB3,CSF1,SH3BP4,PTPRN2,TESC,SFN,PRKN,AVPI1,NEK10,DOCK1,ARHGAP22,NTRK3,PIBF1,DOCK2,PPP1R9A,TBC1D19,CDC14B,BCL6,ACVR2A,PROS1,MET,HSPA2,IGFBP3,CSN2,PTPN6,CD40,WARS,SMAD3,CAMK2N1,RANBP2,NRG3,PTPRJ,ITGA2,DUSP19,RGS10,HGF,ARFGEF3,TENM1,TNIK,LPAR2,ARHGEF11,PAK5,PPP2R3A,ARHGAP44,SYDE2,CHN2,PRKCD,SGK1,AFAP1L2,SH3PXD2B,IQGAP3,TNFRSF11A,SYK,DUSP1,PCSK6,RIN2,CRIM1,ASAP3,PHACTR2,AGAP2,CCNG1,ARHGAP32,TLR6,LEPR,MGMT,DKK1,DDAH1,SUGT1,DOCK7,MAP2K6,ACER2,DLG2,TBC1D4,MMP16,MAP3K20,PKIA |
| 2.034e-04 | -8.50 | VALK_AML_CLUSTER_3 | MSigDB lists | VALK_AML_CLUSTER_3 | 28 | 10 | 17377 | 1707 |
TRIM16,DOCK1,ARHGAP22,RAP2A,MAP7,LAPTM4B,COL4A5,PLS1,CEBPD,QPRT |
| 2.037e-04 | -8.50 | CTDSPL (CTD small phosphatase like) | protein interactions | 10217 | 84 | 20 | 17029 | 1718 |
FAM171B,SLC3A2,CEMIP2,AKAP5,ITGA6,ADD2,PSD3,TJP1,PPP1R9A,PCDH7,CACHD1,NUMBL,GPRIN1,MARVELD2,DAB2IP,TBC1D4,KIAA1549,ADGRL2,ATP2B1,ATP2B4 |
| 2.041e-04 | -8.50 | EGF-like_CS | interpro domains | IPR013032 | 191 | 35 | 18492 | 1811 |
TENM1,BTC,CELSR1,CELSR3,LRP4,LDLR,SELL,GAS6,BCAN,DNER,HMCN1,EFEMP1,NELL2,VWDE,SCARF2,ATRNL1,PROS1,NTNG1,SLIT2,TGFA,VLDLR,C1R,F12,HEG1,NRG3,FAT4,FBN1,CCBE1,THBS4,FAT1,MATN2,BMP1,EGFL7,TMEFF2,TLL2 |
| 2.073e-04 | -8.48 | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | 176 | 33 | 17377 | 1707 |
ACSL1,TTC39B,IL15,RECK,ARHGAP22,HERC5,HERC6,DDX60L,F3,PLS3,MCOLN2,GRHL1,PMAIP1,ERRFI1,CKAP4,PARP9,VEGFC,USP2,FERMT2,SLC25A28,ATF3,CA13,ISG20,WARS,CACHD1,GBP1,NCOA7,GRB10,TNFSF15,HS3ST3B1,CMPK2,SLFN5,CSRP2 |
| 2.073e-04 | -8.48 | GSE2706_2H_VS_8H_R848_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_UP | 176 | 33 | 17377 | 1707 |
MAN2B2,NMNAT3,NUDT10,ATP8A1,ZCCHC24,BACE1,BLVRB,ABAT,DOCK3,DENND3,F3,ARHGEF10L,SLC22A18,SGK1,PRKACB,FES,CYP1B1,QSOX1,MPP1,NFIA,NPC2,MGMT,AHRR,IQCK,TMEM154,TIFA,ZNF697,PLXDC2,KIAA0513,RNF130,GEM,CRYL1,ABCG1 |
| 2.073e-04 | -8.48 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP | 176 | 33 | 17377 | 1707 |
UST,EPHA3,GATA3,STAT5B,TGFBR3,EOMES,SLC7A11,SLC6A15,ST8SIA1,SP140,THSD1,ARAP2,SLC37A1,CRIM1,SH2D2A,MVD,ARID5B,HIP1,RYR2,TTYH2,PHACTR2,COTL1,PRDM1,TLR6,GABARAPL1,ENTPD1,ERN1,C1orf21,NCOA7,BMPR1A,ATP2B4,STOM,MEF2C |
| 2.088e-04 | -8.47 | MODULE_52 | MSigDB lists | MODULE_52 | 417 | 64 | 17377 | 1707 |
UGDH,LDLR,RAC3,EPCAM,EPB41L3,ASNS,GULP1,SERPINH1,IL1RAP,SEMA6C,DBN1,PRAME,PFKFB2,CAP2,KCND3,DSP,FGFR1,INHBC,INSIG1,EIF4EBP1,PLK2,WWTR1,LAMB1,BMP1,SEMA3C,TPM1,TYRO3,GNG12,COL9A3,FN1,IL32,ITGA6,ST6GAL1,EPS8,ZIC2,PHLDA2,GAS1,DDIT4,EFEMP1,SLC7A11,MSMO1,MYC,SMTN,IGSF3,FADS1,QSOX1,MSX1,PNP,MYO10,CRIM1,FHL2,STEAP1,PLOD2,RND3,FAT1,RAI14,SLC7A5,SVIL,PAX9,CDH2,OCLN,PKIA,DDIT3,CSRP2 |
| 2.093e-04 | -8.47 | positive regulation of protein metabolic process | biological process | GO:0051247 | 1637 | 199 | 17256 | 1658 |
ACSL1,ACVR1,FGF13,DNAJC3,LDLR,GATA3,NPM1,STAT5B,CEBPA,PRKCA,SNX9,STK24,NOS1AP,F3,GSDME,PMAIP1,RAP2A,ITGB3,EPHB6,PCOLCE2,TLR4,ENO1,PRKACB,RASGRP1,PDGFRB,TNK2,GCNT2,COL4A3,ACVR1C,TGFA,LRRK2,PRKAR2B,ACVR2B,ROR1,F12,INHBC,GSN,GPRC5B,NCKAP1L,CCBE1,PLK2,ERN1,TNFRSF1A,BBC3,DIRAS1,NRP1,PPARGC1A,MAGI2,CACUL1,PRKAA2,LONRF1,TYRO3,FN1,FBXO4,SLK,JDP2,SORBS3,TNFRSF10C,PFN2,TNFRSF19,RNF180,EEF2,IGF1R,MYC,PRELID1,SREBF1,ADCY6,INAVA,PRR16,HMGCR,PAK1,FGFR4,RPL26,ATP5IF1,MSTN,VLDLR,EFNA3,PACSIN3,DUSP9,WWC1,STRADB,HIP1,PDE8A,ARRDC4,PLCB1,FAM162A,HERPUD1,MAPKAPK2,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,EPHA3,PRKN,NEK10,AVPI1,RNF144A,IL15,HECW2,NTRK3,LCP2,TNKS1BP1,DDR1,PIBF1,PPP1R9A,TLR3,CDC14B,DACT1,BCL6,ACVR2A,DAB2IP,MET,HSPA2,PERP,IGFBP3,ALG10B,FZD1,FZD4,NOP53,ADCY1,RNF125,VIM,PRKCQ,WNT11,PXYLP1,RARRES2,CD40,ASPH,FGFR1,C4BPB,SNCA,SMAD3,NRG3,RNF217,BEX3,APELA,PEMT,WFS1,ITGA2,MAP3K21,DUSP19,TNFSF15,HGF,BMPR1A,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,CD276,LRP4,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,BMP6,NEDD4,GSAP,PRKCD,RASD2,GHR,AFAP1L2,YBX3,IQGAP3,TNFRSF11A,SYK,SPRY2,PARP9,VEGFC,RAPGEF2,PRICKLE1,GAREM1,RACK1,TLR6,GPLD1,DKK1,GPR37,PTPRC,TRIB3,DOCK7,ACER2,MAP2K6,XBP1,LRRK1,BMP4,MAP3K20,ATP2B4,BTRC,LARP1 |
| 2.098e-04 | -8.47 | GGGCATT,MIR-365 | MSigDB lists | GGGCATT,MIR-365 | 106 | 23 | 17377 | 1707 |
BCL11B,ACVR1,EIF4E3,RAPGEF4,UBAC2,ADAMTS6,SATB2,PRDM1,CREB5,TIAM2,EFEMP1,ENTPD7,AKT3,SGK3,SRGAP1,BMP1,SGK1,VGLL4,ETV1,NR3C2,RNF152,TLL2,HMGCR |
| 2.102e-04 | -8.47 | Fc gamma R-mediated phagocytosis | KEGG pathways | hsa04666 | 90 | 21 | 7161 | 730 |
PAK1,PLA2G4A,VAV3,WASF3,INPPL1,MYO10,ASAP3,PLPP2,PRKCA,DOCK2,SCIN,PTPRC,PLPP1,GSN,PRKCB,AKT3,PRKCD,MARCKS,PLD1,SYK,GAB2 |
| 2.102e-04 | -8.47 | Fc gamma R-mediated phagocytosis | KEGG pathways | ko04666 | 90 | 21 | 7161 | 730 |
PAK1,PLA2G4A,VAV3,WASF3,INPPL1,MYO10,ASAP3,PLPP2,PRKCA,DOCK2,SCIN,PTPRC,PLPP1,GSN,PRKCB,AKT3,PRKCD,MARCKS,PLD1,SYK,GAB2 |
| 2.132e-04 | -8.45 | GSE21033_1H_VS_12H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_1H_VS_12H_POLYIC_STIM_DC_UP | 169 | 32 | 17377 | 1707 |
ATL1,SESN2,LCA5,NR4A1,MPP1,ITGA6,DNAJC6,GATA3,TUBE1,PSD3,MAFB,NTRK3,SYT14,MBNL2,MAGI3,SLC9A7,ADAMTS17,ID3,OTUD1,IGF1R,MGAT1,TACC2,KMO,MATN2,XBP1,RGS10,TSC22D1,ERRFI1,RNF157,FMNL2,RASGRP1,RRAGD |
| 2.139e-04 | -8.45 | GO_CARDIAC_CONDUCTION | MSigDB lists | GO_CARDIAC_CONDUCTION | 80 | 19 | 17377 | 1707 |
TRPM4,SCN5A,KCNIP3,CACNG3,ANK2,PKP2,RYR2,ATP1B1,KCND3,DSP,CACNB4,GJC1,KCNJ4,KCNK15,SCN1B,CACNB2,DSG2,CACNA2D1,ATP1A3 |
| 2.153e-04 | -8.44 | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN | 191 | 35 | 17377 | 1707 |
LONRF1,LGALS3,RECK,NRN1,CEBPA,ABHD4,IKZF2,KIAA1958,IGF1R,SAMD11,ZDHHC23,MAP7,TOX,GFI1,RAPGEF5,TNK2,TMEM65,DSTN,CYTH3,PHACTR2,GSTO1,ARRDC4,BATF,SAV1,GPLD1,ENTPD1,ARHGAP21,IKZF3,SH3RF1,GPR160,XBP1,P4HA1,INPP5F,CSRP2,RRAGD |
| 2.153e-04 | -8.44 | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_DN | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_DN | 191 | 35 | 17377 | 1707 |
PSTPIP2,PLEKHA5,MORC4,NDRG2,MRPL22,COL18A1,CTBP2,SCD,CA8,BEX2,EPDR1,ASNS,PCBP4,DSG2,CTTN,MED7,NCAM1,ZNF518B,SLC45A3,DUSP1,TES,PTPN13,TMEM126A,HOMER2,PHACTR2,C3orf70,UCHL3,DSP,CENPV,BEX4,HK2,GRB10,MAPK13,SEMA3C,BMPR1A |
| 2.153e-04 | -8.44 | positive regulation of cellular component organization | biological process | GO:0051130 | 1166 | 148 | 17256 | 1658 |
ATP8A1,LDLR,JCHAIN,GATA3,SNX9,RAC3,ARHGEF10L,RND2,PPM1E,PMAIP1,HRK,TMED9,CTTN,PACSIN1,TLR4,SLIT2,IL1RAP,PDGFRB,GPM6A,TGFA,DSTN,LRRK2,FEZ1,GSN,WIPF3,NCKAP1L,BBC3,SERPINI1,ERCC5,OXTR,TPM1,NRP1,PPARGC1A,MAGI2,FN1,PTPRD,FBXO4,JDP2,SORBS3,GPSM2,PFN2,SPIRE1,IGF1R,GATA2,FLRT3,SREBF1,GRIP1,LMAN2,BNIP3,RIMS2,EPB41L5,PAK1,BDNF,ATP5IF1,RHOQ,SLITRK2,VLDLR,HIP1,SLITRK5,PLCB1,FAM162A,BAIAP2,NEGR1,RIPOR2,ADGRB3,SH3GL2,CDH17,HK2,FNBP1L,SHTN1,SFN,EPHA3,BTC,PRKN,DNM3,ID1,DOCK1,GPR65,C4A,PLXNA2,NTRK3,NRXN1,CBLN1,DOCK2,PPP1R9A,CD53,SCIN,UNC13B,ADGRL1,BCL6,DAB2IP,MET,FZD1,FER,PHLDB2,MYLK3,EVL,FZD4,SHANK2,PREX1,PRKCQ,WNT11,AMIGO1,DOCK5,FGFR1,WARS,SNCA,SMAD3,RANBP2,PTPRJ,APELA,PTK7,ITGA2,HGF,COBL,CNTN1,TENM1,ROBO2,BMPR2,LRP4,BIK,EPS8,APBB1,CLSTN2,ARL2,SLX1B,GAS6,EPHB1,ADGRB2,LRRN1,SCN1B,PRKCD,GTF2F2,SH3PXD2B,FIG4,SYK,FES,SYNPO2,MSX1,PXN,RAPGEF2,RACK1,TLR6,MAP1B,MYADM,MPP7,SHOX2,NPHP1 |
| 2.154e-04 | -8.44 | DLG2 (discs large MAGUK scaffold protein 2) | protein interactions | 1740 | 43 | 13 | 17029 | 1718 |
DLGAP1,SCN5A,KCNJ4,MAP1A,FZD4,GRID1,LIN7A,GRIN2D,DLG2,GUCY1A2,KIF1B,ATP2B4,FZD1 |
| 2.155e-04 | -8.44 | SMTTTTGT_UNKNOWN | MSigDB lists | SMTTTTGT_UNKNOWN | 377 | 59 | 17377 | 1707 |
CACNG3,BMPR2,BTBD9,OVOL2,NRXN1,IKZF2,SP8,MTUS1,CCNJ,FOXP2,CHN1,KCTD15,GATA2,ALDOC,FLRT3,FRAS1,LHX6,SRGAP1,BCL6,ACVR2A,TMED9,PDE4D,PPP2R2B,RRAS2,ETV1,GATM,FGFR4,DPYSL5,UNC5C,GPM6A,SLC3A2,MEIS2,USP2,NR6A1,MYO10,KLHL4,DSTN,FOXN3,EDEM3,PREX1,SATB2,ROR1,CTTNBP2NL,RNF44,MAP1B,BCL11A,MAPKAPK2,SLC7A1,EBF1,BACH2,KLF12,GNAO1,PELI2,P4HA1,DLG2,PANK3,KIF1B,MID1,CTNND2 |
| 2.172e-04 | -8.43 | V$STAT6_01 | MSigDB lists | V$STAT6_01 | 236 | 41 | 17377 | 1707 |
PHACTR3,AMOTL1,FN1,FGF13,KLHL13,UGDH,NDRG2,CADM2,MAPK4,SATB1,DACH2,PRRG4,HECTD2,NEO1,TRPS1,TACC2,FLRT3,SGK1,SLC2A12,MARCKS,ST8SIA1,ZNF385A,TUBA1A,KLHL3,RYR2,SLITRK5,SLC25A28,PLEKHA1,BCL11A,GPR150,SLC7A1,PTK7,GNB4,PELI2,PLXDC2,ITGA2,C1orf21,SVIL,INPP5F,SHOX2,FOXA1 |
| 2.179e-04 | -8.43 | lung-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour-atypical | 511 | 75 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,RASAL2,CHUK,NTRK3,GRK6,PRKCA,LPIN3,DDR1,IKZF2,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,SLC2A12,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,BCL11A,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,NRP1,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PKN1,EPHB1,COL27A1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,PAK1,FGFR4,NUAK2,STRADB,OBSCN,CDC42BPA,MAPKAPK2,TRIB3,FGR,PKN3,AKT3,MAP2K6,NEK11,UACA |
| 2.179e-04 | -8.43 | NAD metabolic process | biological process | GO:0019674 | 69 | 17 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,MDH1B,PCK2,ENO1,NUDT17,PARP9 |
| 2.184e-04 | -8.43 | endoplasmic reticulum part | cellular component | GO:0044432 | 1314 | 162 | 18223 | 1724 |
ACSL1,DNAJC3,ITPR2,ABHD4,NOS1AP,TXNDC5,CYP51A1,RTN1,SEC16B,SLC10A7,CHRDL1,COL19A1,TMED9,RASGRP1,CYP1B1,ATL1,ERGIC1,COL4A3,WLS,TGFA,JPH1,LRMP,NFE2L1,HACD1,INSIG1,RASGRF2,P4HA2,ERN1,TYRO3,ALOX5AP,FN1,SEC24D,CYP2J2,DHCR24,ELOVL7,CYP4V2,SCD,SPINK5,PGAP1,MYORG,RNF180,GALNT1,BNIP1,BCHE,MSMO1,FLRT3,SREBF1,LMAN2,MOXD1,NCEH1,COL9A2,CKAP4,HMGCR,FADS1,ENAM,QSOX1,B3GLCT,SLC37A1,RNF170,SLC27A2,COL4A4,MGST3,EDEM3,GPSM1,RYR2,COLGALT2,SHISA2,HERPUD1,MFSD2A,CSF1,SQLE,PTPRN2,PLD1,DHCR7,CDH2,OSBPL6,CREB3L2,PLA2G4A,ELOVL4,LPCAT2,C4A,XYLT1,COL18A1,LPIN3,SEZ6L2,CANX,COL14A1,CYP26A1,CDS1,COL22A1,ERG28,TLR3,PDZD8,ERO1B,COL25A1,ZDHHC6,REEP1,PROS1,SERPINH1,IGFBP3,ALG10B,ANTXR2,EVA1A,COL6A2,TMEM67,EBPL,TMEM43,LRRC8B,CYB5R2,TRAM1L1,C3orf52,RNF125,TRIQK,ASPH,ATP10D,GJC1,PEMT,WFS1,LAMB1,ALG11,P4HA1,RCN3,CYP2U1,MBOAT2,NR3C2,RETREG1,COL9A3,CLGN,BACE1,UBAC2,CLSTN2,COL4A5,NOTUM,GAS6,GDPD5,COL27A1,SOAT2,STC2,SGK1,CERS4,ESD,TESPA1,FKBP14,CES3,AGPAT4,ELOVL3,ARHGAP32,ILDR2,LRAT,GPR37,EDA,PLOD2,FBN1,FMO4,XBP1,SRD5A3,OSBPL5,MYRF,BMP4,CERS1,PTGES,ABCG1 |
| 2.185e-04 | -8.43 | GSE22045_TREG_VS_TCONV_DN | MSigDB lists | GSE22045_TREG_VS_TCONV_DN | 162 | 31 | 17377 | 1707 |
RPS20,SLC40A1,MXI1,GALNT12,HEBP1,DNAJC6,NFIA,CBY1,TMEM170B,CCNG1,PRKCA,SNTB1,AMDHD1,PPP2R3A,METAP1D,ADPRHL1,RIMKLB,KIAA0895,LMLN,PMEPA1,IGIP,SVIL,LRP6,GRB10,FHIT,CTTN,PDE4D,STXBP1,MLLT3,ACSM3,ZNF629 |
| 2.185e-04 | -8.43 | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP | MSigDB lists | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP | 162 | 31 | 17377 | 1707 |
CARD6,EVL,PDK1,KDM5B,PNRC1,PRSS12,RAPGEF4,SELL,CALCRL,PSD3,TDRKH,PLEKHA1,SESN1,SKI,NEGR1,ID3,TGFBR3,RALGPS2,AKT3,MYC,INPP4B,KCNMB3,RGS10,ADCY6,SHF,IPCEF1,DISP2,RRAS2,DIRC2,AMPD1,ABCG1 |
| 2.189e-04 | -8.43 | superpathway of cholesterol biosynthesis | BIOCYC pathways | HUMAN_PWY66-5 | 25 | 10 | 902 | 105 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,DHCR7,HMGCR |
| 2.197e-04 | -8.42 | V$OCT1_04 | MSigDB lists | V$OCT1_04 | 221 | 39 | 17377 | 1707 |
BCL11B,FGF13,PTPRD,GABRG2,CADM2,SEL1L3,FOXG1,PPP2R3A,FOXP2,GALNT1,ZNF362,UNC13B,SLC7A11,MPPED2,BCL6,KCNS3,TSPAN13,NCAM1,MOXD1,ETV1,FES,GAB2,GPM6A,NR6A1,NFIA,ATOH1,ZFPM2,JAM3,ZIC1,PLAGL1,PRKCB,MAP2K6,GNAO1,ZBTB20,DLG2,SHOX2,MID1,NR3C2,MEF2C |
| 2.197e-04 | -8.42 | GO_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | MSigDB lists | GO_REGULATION_OF_SYNAPSE_STRUCTURE_OR_ACTIVITY | 221 | 39 | 17377 | 1707 |
ROBO2,GRIK2,SYT12,LRP4,CLSTN2,NTRK3,EPHB1,NRXN1,BCAN,ABHD6,CBLN1,PPP1R9A,CTNNA2,NEDD4,CNTN4,UNC13B,LRRN1,FLRT3,DAB2IP,NCAM1,STXBP1,DBN1,BDNF,DISC1,SLITRK2,RAPGEF2,SHANK2,SLITRK5,SNAP25,AMIGO1,BAIAP2,DKK1,SNCA,PLK2,OXTR,CDH2,MAGI2,LZTS1,MEF2C |
| 2.197e-04 | -8.42 | V$HNF6_Q6 | MSigDB lists | V$HNF6_Q6 | 221 | 39 | 17377 | 1707 |
BCL11B,NMNAT3,SLC6A9,CHCHD7,GRIK2,PLAG1,CLSTN2,NOVA1,PFN2,SP8,MTUS1,ZNF827,CHN2,KCTD15,CNTN4,KCNAB1,COL25A1,FLRT3,GTF2F2,PRICKLE2,MN1,SSH3,MSTN,HNF4G,AGPAT4,PRDM13,VLDLR,ZIC1,RERE,ZNF711,NSD1,GNAO1,INPP4B,NEK11,PAX9,DLX2,SEMA3A,HOXB9,MEF2C |
| 2.216e-04 | -8.41 | GO_CELLULAR_MACROMOLECULE_LOCALIZATION | MSigDB lists | GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 1177 | 152 | 17377 | 1707 |
EXPH5,UGT8,FGF13,GRIK2,NPM1,SNX9,NUP62CL,TRPS1,ADPRHL1,SEC16B,PMAIP1,RAP2A,RAB26,LIN7A,TMED9,CTTN,COG3,PACSIN1,TLN2,MYRIP,CPE,TBC1D8,DBN1,GDAP1,ITGB7,KCNIP3,WLS,ANK2,LRRK2,GSN,TNFRSF1A,BBC3,NRP1,MAGI2,RRAGD,LATS2,CELSR1,TBC1D1,SEC24D,STXBP6,APBA1,BBS9,TTC30B,PGAP1,RPL13A,CACNB2,RPS11,LRP6,STXBP1,RIMS2,RPS23,ZNF385A,MID2,DISC1,RPL26,TBC1D8B,TTC30A,RYR2,OBSCN,STRADB,PEX5L,HERPUD1,SPATA7,TBC1D2,TEX15,RPL28,FCHO2,WDR19,SH3BP4,RAB31,HK2,CDH2,TESC,SIX2,ID1,RHOD,AKAP5,PKP2,NRXN1,PIBF1,TBC1D30,ZFYVE9,SCIN,EPB41L3,REEP1,BCL6,ZDHHC23,MAP7,MARCKS,RPL26L1,RAB27B,ZNF365,SNX10,KCNB2,RPS13,DPP10,PTPRU,TRAM1L1,WNT11,SYNJ2BP,PYGO1,ATP1B1,RAB38,TBC1D16,RANBP2,IFT81,KPNA3,MID1,RAB30,RPS20,TNIK,MXI1,TSPAN15,LRP4,IPO5,UBAC2,ARL2,RASD1,P2RY1,GAS6,TSPAN17,NEDD4,RPL34,EHD3,RASD2,PRKG2,SH3PXD2B,DYNC2H1,TBC1D9,MYO6,RRAS2,SYK,MSX1,RAB3B,RAB6B,RAPGEF2,RPL21,FERMT2,PRICKLE1,SKAP1,RERE,HOMER3,RPL12,MYADM,NACC2,TERT,DLG2,RPL4,HK1,BMP4,RPS12,TBC1D4 |
| 2.235e-04 | -8.41 | GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_UP | MSigDB lists | GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_UP | 184 | 34 | 17377 | 1707 |
COL9A3,SERINC5,RASAL2,HEBP1,DNAJC3,MLF1,IPO5,ADD2,ZNF215,GPSM2,APBA1,FHOD3,TRPS1,PLS3,MAP1A,EEF2,SLC7A11,RRAS2,TSHR,ULBP1,HRASLS,TDRD3,ACO1,CDC42BPA,COTL1,C9orf116,HTR7,TMCO3,IKZF3,C1orf21,MAP9,NEK11,MAGI2,MMP16 |
| 2.235e-04 | -8.41 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | 184 | 34 | 17377 | 1707 |
MXI1,ZNF516,ZNF395,GABRB2,ESRP1,PSD3,FAM13A,GDPD5,PFN2,CYP26A1,NOS1AP,RPL34,CHN2,TLR3,PDZD8,MCF2L,SGK1,ZFP36L2,RASGRP1,CEBPD,IGFBP3,DUSP1,TUBA1A,PDK1,PLEKHA1,JAM3,IRS2,GNAO1,HGF,ZBTB20,TBC1D4,NR3C2,SLC16A10,STOM |
| 2.254e-04 | -8.40 | cell-substrate adherens junction | cellular component | GO:0005924 | 400 | 60 | 18223 | 1724 |
ARHGAP26,EFNB2,SORBS1,MRC2,ITGA6,ARHGAP22,ARL2,NPM1,ENAH,SORBS3,RPL13A,PPFIBP1,RPS11,FLRT3,ITGB3,EHD3,SCARF2,MARCKS,CTTN,TLN2,RRAS2,TSPAN9,FES,PDGFRB,FZD1,RPS13,EPB41L5,PAK1,PDLIM7,PHLDB2,SYNPO2,EVL,PXN,TES,CAPN5,ASAP3,FHL2,FERMT2,VIM,TNS1,PALLD,SNTB1,PEAK1,PTPRC,GSN,LMLN,DOCK7,RPL12,RND3,FAT1,PTK7,ITGA2,SVIL,RPL4,SPRY4,NRP1,CDH2,CSRP2,MME,LPP |
| 2.263e-04 | -8.39 | regulation of steroid biosynthetic process | biological process | GO:0050810 | 82 | 19 | 17256 | 1658 |
FGFR4,MVK,MVD,FASN,SCD,BMP6,CYP51A1,HMGCS1,IDI1,INSIG1,STARD4,SREBF1,SQLE,PPARGC1A,DHCR7,GFI1,SNAI2,ABCG1,HMGCR |
| 2.280e-04 | -8.39 | V$FREAC4_01 | MSigDB lists | V$FREAC4_01 | 141 | 28 | 17377 | 1707 |
PNRC1,NR4A1,OTX1,PRDM1,ROR1,IKZF2,MBNL2,NAALADL2,HMCN1,NEDD4,PPP2R3A,PLS3,TRPS1,FOXP2,MSC,KLF12,FRY,ABI3BP,SH3RF1,PELI2,ADRB1,MCC,SPRY4,MAST4,SHOX2,GFRA1,POU3F3,DUSP1 |
| 2.280e-04 | -8.39 | GO_SITE_OF_POLARIZED_GROWTH | MSigDB lists | GO_SITE_OF_POLARIZED_GROWTH | 141 | 28 | 17377 | 1707 |
DBN1,GPM6A,FGF13,SHANK2,LRRK2,APBB1,EPS8,PREX1,NDRG2,SNAP25,NRXN1,PALLD,GDPD5,RAC3,PPP1R9A,CPEB1,TIAM2,SNCA,CCDC120,DOCK7,GPRIN1,FRY,FLRT3,TMOD2,MARCKS,CTTN,NRP1,COBL |
| 2.282e-04 | -8.39 | cardiac septum development | biological process | GO:0003279 | 102 | 22 | 17256 | 1658 |
ACVR1,BMPR2,ANK2,GATA3,NSD2,ADAMTS6,WNT11,PRDM1,ZFPM2,SAV1,HEG1,TGFBR3,HEYL,PTK7,SEMA3C,BMP4,BMPR1A,NRP1,SMAD6,PCSK5,HEY1,FZD1 |
| 2.292e-04 | -8.38 | GO_POSTSYNAPTIC_MEMBRANE | MSigDB lists | GO_POSTSYNAPTIC_MEMBRANE | 199 | 36 | 17377 | 1707 |
GRIK2,GABRB2,APBB1,CLSTN2,GABRG2,PSD3,KCTD12,GABRR2,P2RY1,PRR7,CBLN1,NCS1,KCNJ4,SEMA4F,CHRNA5,LIN7A,GRIP1,CADPS2,MPDZ,CHRM3,DLGAP1,DISC1,ANK2,HOMER2,SHANK2,GRID1,CHRNA6,NLGN4X,ARHGAP32,CPEB1,HOMER3,CAMK2N1,GRIK4,GRIN2D,DLG2,LZTS1 |
| 2.293e-04 | -8.38 | V$MEIS1_01 | MSigDB lists | V$MEIS1_01 | 229 | 40 | 17377 | 1707 |
UST,SORBS1,FGF13,GCAT,PLXNA2,CREB5,DYNC1I1,TNFRSF19,TNKS1BP1,FOXP2,IKZF5,PDZD7,ABI3BP,FLRT3,PCBP4,SAMD11,BEND4,PPP2R2B,NCAM1,ERRFI1,ETV1,MYT1,C15orf41,CKAP4,GLI1,GAB2,ATL1,ESRRG,ANK2,FGF12,WWC1,ARRDC4,HOXA1,HTR7,KIAA0355,GNAO1,B3GALT2,KLF5,NRP1,DDIT3 |
| 2.294e-04 | -8.38 | cellular component organization | biological process | GO:0016043 | 5372 | 580 | 17256 | 1658 |
ARHGAP26,DOC2A,AASS,RECK,TUBE1,NPM1,CEBPA,CADM2,NHP2,BCAN,SNX9,EYA4,SKI,TGFBR3,IKZF5,PMAIP1,DNAH6,RAP2A,TMED9,COG3,NKX2-1,SMIM20,DCC,CAP2,DSTN,GJB2,TGFA,LRRK2,NFIA,FEZ1,PRKAR2B,KCND3,WIPF3,MAP9,ALDOA,ARHGAP28,BBC3,TMOD2,ERCC5,TPM1,DNHD1,VASH2,MEF2C,ITGA6,SLK,TJP1,GPSM2,BBS9,FOXG1,TTC30B,GRPEL2,CHN1,SYCP2,RSL24D1,BNIP1,FRY,CACNB2,FLRT3,LMAN2,TOX,CADPS2,LOXL4,NCAM1,FIGN,JAM2,STXBP1,FMNL2,GFRA1,RPS23,LRP12,ZNF385A,HMGCR,BDNF,SPATA6,ARID5B,HIP1,SMARCD3,PLS1,SNAP25,TAF4B,CLN5,TEX15,SH3GL2,ADAMTS3,CDH17,CLMN,LAPTM4B,CDH2,SHTN1,TFCP2L1,DNM3,TMSB15A,MYO1B,PKP2,ADD2,NRXN1,EPB41L3,GPRIN1,COL25A1,RTKN2,ZNF365,DNAH5,SNX10,PERP,KCNB2,FZD1,SSH3,MYLK3,COL6A2,GAPDH,FZD4,NPM3,ADCY1,WNT11,RAB38,DSP,GABARAPL1,GJC1,IRS2,ARHGAP21,WWTR1,LAMB1,PAM,P4HA1,RAB30,FARP1,C1QTNF3,ROBO2,BIK,GAS6,SLC12A6,PKN1,EPHB1,KCNC4,COL27A1,NEO1,LRRN1,BHLHA15,GAS2L3,NPTXR,FES,PDLIM7,TRPM4,B9D1,CLYBL,RAPGEF2,ATP11A,HEG1,NSD1,RPL12,PCDHB7,AKT3,GNAO1,NEK11,JHY,FOXA1,PHC1,TLL2,CACNG3,FGF13,TRIM16,SYT12,HDGFL3,SYT14,PLS3,RND2,SEC16B,HPS1,MARVELD2,ITGB3,TBC1D32,LIN7A,COL19A1,TLN2,ETV1,NEB,DBN1,ITGB7,MARK1,COL4A3,ABCC4,ANK2,PLEKHA1,TSKU,TCF7L1,MAP2,TNFRSF1A,AHNAK2,PIK3C2B,TC2N,CHMP4C,PRKAA2,KCNV1,TYRO3,SORBS3,PFN2,MLC1,DOK5,SPIRE1,FHOD3,NUMBL,KIAA1958,SEMA4F,IGF1R,ABCA5,GAN,LRP6,BNIP3,PAK1,DPYSL5,UNC5C,EFNA3,SPATA13,STRADB,OBSCN,SLITRK5,SDK1,BAIAP2,NAP1L5,ATPAF2,SEMA3A,SFN,PRKN,ID1,DOCK1,LPCAT2,RBFOX2,NTRK3,RADIL,TNKS1BP1,PCLO,PPP1R9A,SEMA6A,CTNNA2,TACC2,BCL6,CLVS2,SNAI2,CTH,INTU,EVL,TMEM67,TUBA1A,TDRD3,NOP53,PRDM13,THSD4,VIM,JAM3,SMAD3,RANBP2,IFT81,NRG3,GBP1,PTK7,KCNG1,ITGA2,PTPRS,HGF,SEPT5,CTNND2,RETREG1,CNTN1,TENM1,COL9A3,KIZ,DYRK3,BMPR2,PAK5,APBB1,HBE1,USP30,ARHGAP44,TECPR1,MAP1A,SGK1,SH3PXD2B,MICAL2,NUAK2,FERMT2,PALLD,MAP10,DKK1,DOCK7,TMEM237,FAT4,L3MBTL4,FBN1,MYRF,TBC1D4,ATP8A1,LDLR,VAMP8,GATA3,ENAH,PRKCA,RAC3,DACH2,STK24,TRPS1,TYMP,NDUFB8,KCNS3,SP140,PACSIN1,PLTP,GDAP1,ACVR1C,LRMP,DNAJC6,DEPTOR,BNIP3L,EFHC1,TNS1,AGO4,ARHGEF26,NCKAP1L,PLK2,BMP1,SEMA3C,SPART,UNC5B,NRP1,EFNB2,LRFN5,INPPL1,ALOX5AP,TBC1D1,PTPRD,DHCR24,OPHN1,MRPL22,SLC1A3,APBA1,DYNC1I1,CHD5,MECOM,MCOLN2,ABLIM1,NAV1,CNTN4,PDZD7,MYC,PRELID1,PRKG1,GRIP1,PRR16,MAST4,COL9A2,BOD1,EPB41L5,DISC1,PLEKHA8,COL4A4,VLDLR,PACSIN3,TTC30A,NSD2,PEX5L,CDC42BPA,MMP15,PLEKHH2,VPS37D,CECR2,THBS4,WDR19,MATN2,DYNC2LI1,MPP2,SFMBT1,IQSEC2,SMYD3,EPHA3,NBL1,AMOTL1,TCTN2,RHOD,ST14,GPR65,PLXNA2,MSR1,KCTD12,DDR1,COL14A1,CCDC120,NAP1L3,DAB2IP,MARCKS,SERPINH1,GAB2,TMEM43,SHANK2,PREX1,NLGN4X,PRKCQ,CBY1,SATB2,ATOH1,PYGO1,ATP1B1,ATP10D,PATJ,SNCA,TDO2,PRKCB,ASIC1,CCNA1,GRB10,KLF5,ATG5,STON2,COBL,MID1,KCTD1,HACE1,WASF3,PLSCR4,ATP9A,EPS8,KIF5C,ARL2,GDPD5,NEDD4,HOPX,RASSF8,KDM7A,LRRC55,SOAT2,AFF2,FIG4,DYNC2H1,SEPT3,SPRY2,VAV3,SYNPO2,PXN,ZDHHC15,TERT,PCGF2,SVIL,MYOM2,OCLN,DDIT3,B4GALT7,ATP1A3,MPZL3,UGT8,KIF5A,DNER,CACNB4,QPRT,ARHGEF10L,TUBB4A,LRRC6,GRHL1,ABI3BP,POF1B,CTTN,IL1RAP,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,ATL1,GPM6A,SESN2,SKAP2,YAP1,EML1,GSN,NCAM2,PPARGC1A,MAGI2,FRMD5,BCL11B,FN1,BVES,SEC24D,RHOBTB1,ATP6V1E2,LAMC3,SPINK5,PHGDH,SATB1,ADGRG6,DDIT4,PCDHB14,ZNF354A,INAVA,LIMCH1,CAND2,NOS3,SNX7,CDH26,ATP5IF1,RHOQ,SLITRK2,PARD3B,ADGRB3,FCHO2,FAT1,HK2,RAB31,NKX2-8,FNBP1L,DMXL2,SORBS1,CELSR3,PSTPIP2,COL18A1,COBLL1,TDRKH,PIBF1,DOCK2,SCIN,KCTD15,SETDB2,PDZD8,UNC13B,ERO1B,CDC14B,REEP1,MAP7,GULP1,MET,TMEM120B,HSPA2,NTNG1,SEMA6C,SP140L,FER,PHLDB2,GCA,PTPN6,SYNJ2BP,AMIGO1,CD40,CENPV,ARMC4,KPNA3,TRIM34,DISP1,MAST1,TNIK,CLGN,ARHGEF11,LRP4,CMTM8,COL4A5,SLX1B,MCU,NKX6-1,FSD1,SCN1B,PRKCD,EHD3,DSG2,KIAA0319,IQGAP3,TESPA1,RAB3B,MSX1,KDM5B,SYBU,MEI1,PEAK1,RERE,MAP1B,MYADM,RND3,MPP7,NACC2,CTSV,GEM,MMP16,NPHP1,MAP3K20,ABCG1,STOM |
| 2.300e-04 | -8.38 | NAD biosynthetic process | biological process | GO:0009435 | 51 | 14 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1,NUDT12,PARP9,QPRT |
| 2.309e-04 | -8.37 | ion channel regulator activity | molecular function | GO:0099106 | 94 | 21 | 17224 | 1680 |
DPP10,KCNV1,KCNIP3,VAMP8,PACSIN3,AMIGO1,RACK1,SGK2,NRXN1,HPCAL4,NEDD4,LRRC55,KCNMB4,KCNAB1,SCN1B,KCNMB3,PRKG1,SGK3,KCNS3,SGK1,TSPAN13 |
| 2.310e-04 | -8.37 | GO_NAD_METABOLIC_PROCESS | MSigDB lists | GO_NAD_METABOLIC_PROCESS | 50 | 14 | 17377 | 1707 |
PFKFB4,NMNAT3,GAPDH,PNP,ENO2,KMO,PFKFB2,ALDOC,ALDOA,HK2,HK1,NUDT12,ENO1,QPRT |
| 2.312e-04 | -8.37 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | 177 | 33 | 17377 | 1707 |
GABRG2,FAM117B,CHN1,ZNF362,FRY,CDC14B,MARVELD2,GPR155,JAKMIP2,MDH1B,MORN4,MAST4,TNFRSF11A,SNAI2,C3orf67,KDM5B,FHL2,EFHC1,CTTNBP2NL,CCNG1,C3orf70,PLCB1,SPATA7,ZFP62,KCNMB4,CSF1,MAP2K6,WDR19,ERCC5,DBP,NRP1,APBA2,ABCG1 |
| 2.312e-04 | -8.37 | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 177 | 33 | 17377 | 1707 |
PHACTR3,ANTXR2,TRIM2,FN1,ATP9A,MGST3,EXOC6B,GDPD1,ELMOD1,C20orf194,IL13RA1,NPC2,CPEB1,CYP26A1,IL17D,ZNF711,OTUD1,KCNMB4,MYADM,RND3,MAP2,EHD3,NCOA7,B3GALT2,PGM2L1,GRB10,KIF21A,RAB27B,MYRIP,LRP12,ATP2B4,CEBPD,DUSP1 |
| 2.321e-04 | -8.37 | regulation of neurotransmitter secretion | biological process | GO:0046928 | 57 | 15 | 17256 | 1658 |
PRKN,KCNMB4,UNC13B,KMO,SYT12,LRRK2,ASIC1,SEPT5,KCNC4,STXBP1,PFN2,PPP1R9A,RIMS2,SNCA,MEF2C |
| 2.340e-04 | -8.36 | GTGCCAA,MIR-96 | MSigDB lists | GTGCCAA,MIR-96 | 283 | 47 | 17377 | 1707 |
CREB3L2,EPHA3,FARP1,SLC6A9,CELSR1,DOCK1,VAMP8,DHCR24,RHPN2,ZIC2,ITPR2,ABAT,FAM81A,NRXN1,CACNB4,NOVA1,SEMA6A,PGAP1,CHST10,EPB41L3,SLC10A7,GAN,ADCY6,ACVR2A,SH3PXD2B,MYRIP,HSPA2,RNF152,PDLIM7,PAK1,GPM6A,RAPGEF4,ARID5B,GRID1,TSKU,TRIB3,DDAH1,PLAGL1,GPRC5B,BACH2,PMEPA1,PLOD2,CSF1,ZNF704,TPM1,XKR4,COBL |
| 2.342e-04 | -8.36 | Pkinase | pfam domains | PF00069 | 348 | 55 | 17054 | 1666 |
PRKAA2,TNIK,LATS2,DYRK3,NEK10,ACVR1,BMPR2,PAK5,SLK,MAPK4,CHUK,GRK6,PKN1,PRKCA,STK24,MOK,SPEG,RPS6KA2,RPS6KL1,PRKCD,MYO3B,SGK3,PRKG1,SGK1,ACVR2A,PRKG2,MAST4,PRKACB,PAK1,MYLK3,MARK1,LRRK2,NUAK2,OBSCN,STRADB,PRKCQ,ACVR2B,CDC42BPA,SGK2,PEAK1,GRK3,MAPKAPK2,DYRK1B,TRIB3,PKN3,PRKCB,MAP2K6,PLK2,AKT3,ERN1,NEK11,MAPK13,LRRK1,MAPK10,MAST1 |
| 2.382e-04 | -8.34 | V$CEBPGAMMA_Q6 | MSigDB lists | V$CEBPGAMMA_Q6 | 237 | 41 | 17377 | 1707 |
PCDH18,FARP1,UGDH,CTBP2,CREB5,NOVA1,CHD5,SEMA6A,SP8,NEDD4,FOXP2,UNC13B,PPFIA2,SLC10A7,LHX6,HS3ST5,TSPAN9,FES,MN1,HNF4G,FZD4,NR6A1,FOXN3,PRDM13,NPM3,PACSIN3,TCEA3,CHRNA6,MARS,PRDM1,GPLD1,ENTPD1,NSD1,GSTO2,NCKAP1L,PTK7,DLG2,ZBTB20,PPARGC1A,MID1,MEF2C |
| 2.389e-04 | -8.34 | GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN | 192 | 35 | 17377 | 1707 |
RPS20,MAN2B2,TRIM2,ITGA6,SORBS3,SATB1,COL14A1,RPL34,ABLIM1,MAP1A,FAM168A,MCF2L,EIF1,ACVR2A,SGK1,ZFP36L2,RPS23,ATP2B1,RPS13,TNK2,TDRD3,FOXN3,FASN,LITAF,PRKCQ,ISG20,BCL11A,HEG1,CD37,RANBP2,RGS10,RPS12,SPOCK3,DDIT3,TPT1 |
| 2.389e-04 | -8.34 | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | MSigDB lists | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | 192 | 35 | 17377 | 1707 |
RGS16,TTC39B,ITGA6,DHCR24,SELL,NDRG2,GABRR2,GRK6,RGS7,DDIT4,IGF1R,SEMA4F,SLC30A4,MYC,MAP7,SGK1,ADCY6,ST8SIA1,RCAN3,PDGFRB,ITGB7,TUBA1A,NR4A1,RASA3,NPC2,ARHGAP21,ID3,RPL28,NACC2,GNB4,SLC7A5,RGS10,SQLE,SERPINI1,LPP |
| 2.391e-04 | -8.34 | BAELDE_DIABETIC_NEPHROPATHY_DN | MSigDB lists | BAELDE_DIABETIC_NEPHROPATHY_DN | 419 | 64 | 17377 | 1707 |
CREB3L2,EXPH5,TYRO3,SERINC5,ZNF516,AASS,GRIK2,PTPRD,ATP9A,SLK,MYO1B,CANX,KBTBD11,PFN2,GAS1,F3,CDS1,PLS3,CYP51A1,TGFBR3,FRY,CACNB2,ITGB3,GHR,SCRN1,GULP1,HSPA2,PRKACB,CEBPD,CAND2,GAB2,CYP1B1,DUSP1,PNMA2,PAK1,CD55,COL4A3,CRIM1,COL4A4,DSTN,ARID5B,NFE2L1,LITAF,FERMT2,C1R,VIM,PRKAR2B,RARRES2,KCND3,PALLD,WARS,BEX4,PLOD2,FAT1,XBP1,RGS10,PAM,RAI14,HPGD,SEMA3C,MAPK10,FNBP1L,MAGI2,MME |
| 2.402e-04 | -8.33 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_DENDRITIC_CELL | 62 | 16 | 17377 | 1707 |
FADS1,ITGB7,MSMO1,ST6GAL1,GTF2IRD1,SETBP1,MARS,PRDM1,TNFRSF17,CANX,PRR7,RAB30,FKBP11,TXNDC5,GLDC,ISG20 |
| 2.402e-04 | -8.33 | GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | 62 | 16 | 17377 | 1707 |
PFKFB4,AK1,GAPDH,ENO2,PFKFB2,ALDOC,MPP1,ALDOA,MPP2,OGDHL,HK2,AK4,DLG2,HK1,ENO1,MAGI3 |
| 2.418e-04 | -8.33 | CHICAS_RB1_TARGETS_GROWING | MSigDB lists | CHICAS_RB1_TARGETS_GROWING | 222 | 39 | 17377 | 1707 |
PRSS12,STXBP6,DHCR24,SCD,ADAMTS6,FAM198B,PHGDH,PGAP1,PCDH7,DDIT4,ASNS,KCNN2,RALGPS2,GAS2L3,TOX,MARCKS,IQGAP3,PCK2,JAM2,SLIT2,IGFBP3,MEIS2,ALDH1L2,THSD4,ARID5B,PRICKLE1,C1R,CDC42BPA,GPC6,TIFA,CCBE1,EIF4EBP1,MATN2,C1orf21,B3GALT2,OXTR,TNFSF4,NRP1,PSPH |
| 2.431e-04 | -8.32 | cardiac conduction | biological process | GO:0061337 | 89 | 20 | 17256 | 1658 |
TRPM4,SCN5A,KCNIP3,CACNG3,ANK2,RYR2,PKP2,KCND3,ATP1B1,DSP,CACNB4,GJC1,KCNJ4,KCNK15,KCNN2,SCN1B,CACNB2,DSG2,CACNA2D1,ATP1A3 |
| 2.434e-04 | -8.32 | NCK2 (NCK adaptor protein 2) | protein interactions | 8440 | 138 | 28 | 17029 | 1718 |
EFNB2,PAK1,WASF3,TNK2,TNIK,SORBS1,DOCK1,REL,EFHC2,ARHGAP32,LCP2,KIAA1217,DDR1,TTC28,PEAK1,SEMA6A,FGFR1,BAIAP2,BCL11A,CHN1,PIK3AP1,WIPF3,LRRIQ3,ABI3,SH3PXD2B,MAGEA6,SPRY2,PDGFRB |
| 2.439e-04 | -8.32 | macromolecule localization | biological process | GO:0033036 | 2248 | 263 | 17256 | 1658 |
THOC5,SIDT1,GRIK2,ATP8A1,LDLR,VAMP8,GATA3,NPM1,STAT5B,SNX9,TRPS1,PMAIP1,RAP2A,RAB26,NDUFB8,TMED9,COG3,PACSIN1,CPE,PLTP,TBC1D8,GDAP1,ACVR1C,WLS,EXOC6B,LRRK2,ABCC2,ACVR2B,ZDHHC14,ENPP1,NRP1,CELSR1,TBC1D1,DHCR24,APBA1,BBS9,RPL13A,GRPEL2,MCOLN2,PDZD7,CACNB2,PRELID2,PRELID1,GRIP1,LMAN2,CADPS2,STXBP1,RPS23,ZNF385A,RIMS2,BOD1,RPL26,PNP,TBC1D8B,PLEKHA8,VLDLR,RAPGEF4,DCHS1,RYR2,HIP1,CALCRL,PEX5L,NPC2,SNAP25,ARRDC4,SPATA7,VPS37D,RPL28,WDR19,SELENOM,CDH2,SMYD3,PLA2G4A,NBL1,SCAMP1,TMSB15A,RHOD,MSR1,PKP2,LCP2,NRXN1,TBC1D30,ZFYVE9,CCDC120,EPB41L3,STARD4,NBEA,RTKN2,RAB27B,ARL4D,SNX10,KCNB2,FZD4,TRAM1L1,WNT11,CBY1,ATP1B1,PYGO1,RAB38,DSP,TBC1D16,ATP10D,PRKCB,MID1,RAB30,THOC3,RPS20,MXI1,ATP9A,IPO5,UBAC2,ARL2,KIF5C,GAS6,P2RY1,TSPAN17,NEDD4,SOAT2,PRKG2,DYNC2H1,MYO6,TBC1D9,SEPT3,LCA5,RAB6B,RAPGEF2,RPL21,ZDHHC15,ATP11A,SKAP1,RPL12,TERT,OSBPL5,XBP1,MCC,HK1,BMP4,DDIT3,EXPH5,UGT8,CACNG3,ACSL1,FGF13,KIF5A,LILRB1,NUP62CL,SLCO3A1,ADPRHL1,SEC16B,AKAP7,TBC1D32,LIN7A,CTTN,TLN2,TLR4,MYRIP,IL1RAP,DBN1,ITGB7,KCNIP3,ABCC4,ANK2,PLEKHA1,SPNS1,GSN,INSIG1,TNFRSF1A,MAGI2,APBA2,CHMP4C,PCSK5,RRAGD,PRKAA2,STXBP5L,SEC24D,HID1,STXBP6,ATP6V1E2,MLC1,PGAP1,SPIRE1,ABCA5,RPS11,FRAS1,LRP6,SNX7,MID2,SLC27A2,OBSCN,STRADB,BAIAP2,HERPUD1,TBC1D2,FCHO2,MFSD2A,HK2,RAB31,SH3BP4,PTPRN2,OSBPL6,TESC,SIX2,PRKN,ID1,AKAP5,CANX,PIBF1,CBLN1,PCLO,SCIN,PDZD8,FABP6,ZDHHC6,REEP1,ZDHHC23,BCL6,MAP7,STEAP3,GULP1,POU2F2,RPS13,DPP10,PHLDB2,PTPRU,NOP53,SYNJ2BP,RANBP2,KPNA3,GBP1,ITGA2,SEPT5,TNIK,TSPAN15,CMTM8,LRP4,TNFSF13B,IGF2BP2,ARHGAP44,RPL34,RAB11FIP5,MAP1A,EHD3,TRIM3,SH3PXD2B,RAB3B,MSX1,PRICKLE1,FERMT2,AGAP2,TLR6,ILDR2,RERE,HOMER3,MYADM,FBN1,MPP7,NACC2,DLG2,RPS12,RPL4,TBC1D4,KIF1B,ABCG1 |
| 2.449e-04 | -8.31 | GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN | 163 | 31 | 17377 | 1707 |
FADS1,VNN2,MICAL2,SEMA6B,GAPDH,ACSL1,LGALS3,FLVCR2,WLS,MPP1,BLVRB,BNIP3L,SMARCD3,VIM,CREB5,NPC2,SLCO3A1,PRRG4,CTIF,CEBPB,HPSE,PELI2,EMILIN2,EIF1,STEAP3,HS3ST3B1,RNF130,DHCR7,IL1RAP,CKAP4,RRAGD |
| 2.457e-04 | -8.31 | GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ENDOGENOUS_STIMULUS | 975 | 129 | 17377 | 1707 |
CGN,ACVR1,ACSL1,GATA3,ASS1,STAT5B,ITPR2,SKI,TGFBR3,FBXO32,AKAP7,CHRDL1,TSHR,SLIT2,PRKACB,PDGFRB,GCNT2,SMAD9,NR6A1,LRRK2,PRKAR2B,ACVR2B,KCND3,FGF17,ENPP1,GNB4,BMP1,OXTR,TNFSF4,PPARGC1A,MAGI2,MEF2C,RRAGD,PRKAA2,GNG12,LATS2,RUNX2,FN1,GABRB2,ATP6V1E2,CA2,IGF1R,EEF2,FLRT3,SREBF1,ADCY6,GRIP1,EPB41L5,PAK1,FGFR4,RHOQ,MSTN,VLDLR,FHL2,RYR2,CPEB1,BAIAP2,PMEPA1,HEYL,RAB31,SH3BP4,SMYD3,ID1,SORBS1,AKAP5,RBFOX2,ZFYVE9,ASNS,ACVR2A,DAB2IP,PDE4D,SNAI2,FZD1,FER,UROS,ADCY1,FGF12,FGFR1,SNCA,IRS2,SMAD3,EIF4EBP1,ITGA2,HPGD,GRB10,BMPR1A,NR3C2,HEY1,BMPR2,ROBO2,ESRP1,IPO5,LRP4,GABRG2,BMP6,NEDD4,NKX6-1,HMGCS1,PRKCD,GHR,GTF2F2,SGK1,KLF9,ERRFI1,SMAD6,SYK,ATP2B1,DUSP1,GSTM2,PXN,MSX1,KDM5B,HNF4G,ESRRG,RAPGEF2,NR4A1,FERMT2,LEPR,GPLD1,GALNT3,CEBPB,TRIB3,PLOD2,FBN1,XBP1,BMP4,TBC1D4,ATP2B4,ATP1A3 |
| 2.464e-04 | -8.31 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | 245 | 42 | 17377 | 1707 |
FARP1,FZD8,PRSS35,KCTD12,SLC12A6,KIAA1217,ABHD6,HMCN1,IL17D,RALGPS2,SLC7A11,AKAP7,GATA2,KMO,OPN3,STEAP3,TSPAN13,NPTXR,TBC1D9,NTNG1,IL1RAP,FZD4,PTPN13,GSTM4,SPATA13,PREX1,MAFB,RARRES2,STEAP1,C9orf116,FGFR1,GLCE,GALNT3,RGS10,PGM2L1,RCN3,MAPK13,HS3ST3B1,CMPK2,TMEFF2,MLLT3,SLC43A1 |
| 2.464e-04 | -8.31 | V$MYB_Q5_01 | MSigDB lists | V$MYB_Q5_01 | 245 | 42 | 17377 | 1707 |
LRFN5,PCSK1N,PPP4R4,SLC6A9,FGF13,DOCK1,HEBP1,CREB5,COLEC10,CANX,PRRG4,SLC9A7,FOXP2,ZNF362,CNTN4,SEC16B,DACT1,FRAS1,LHX6,BEND4,ERRFI1,FIGN,BDNF,GCNT2,SLC37A1,NR6A1,ESRRG,FGF12,OGDHL,RASA3,PRICKLE1,CEBPB,KLF12,ADAMTS3,ALDOA,B3GALT2,KLF5,DLX2,RPL4,NR3C2,CRISPLD1,DDIT3 |
| 2.464e-04 | -8.31 | V$E12_Q6 | MSigDB lists | V$E12_Q6 | 245 | 42 | 17377 | 1707 |
DOC2A,PHACTR3,NBL1,ANKRD13B,KLHL13,ITGA6,SELL,NTRK3,PKN1,CANX,CHD5,BMP6,CYP26A1,EPDR1,MTUS1,COL22A1,UNC13B,GATA2,STC2,CHRDL1,RAB26,MPPED2,MAP7,CNNM2,GFRA1,USP2,COL4A3,NR4A1,GJB2,COL4A4,ANK2,RAPGEF4,PACSIN3,WWC1,AIG1,NEGR1,GPR37,SMAD3,PTPRJ,HEYL,ITGA2,CDH2 |
| 2.465e-04 | -8.31 | regulation of membrane potential | biological process | GO:0042391 | 437 | 65 | 17256 | 1658 |
PRKN,FGF13,GRIK2,PKP2,ABAT,NRXN1,CACNB4,PPP1R9A,CBLN1,NOS1AP,CHRNA5,UNC13B,KCNN2,PMAIP1,SCN2A,SCN3A,KCNH5,ANK2,SHANK2,LRRK2,BNIP3L,FGF12,NLGN4X,CHRNA6,KCND3,ATP1B1,DSP,SNCA,GJC1,PYCR1,KCNMB4,POPDC3,ASIC1,SPART,MEF2C,SCN5A,BVES,SCN8A,GABRB2,SLC25A27,GABRG2,GABRR2,NEDD4,SCN1B,CACNB2,EHD3,DSG2,PRELID1,KCNMB3,BNIP3,RIMS2,TRPM4,ATP5IF1,KCNQ3,CACNA1E,GRID1,RYR2,RACK1,BAIAP2,GRIK4,KCNK15,MPP2,GRIN2D,CACNA2D1,ATP1A3 |
| 2.468e-04 | -8.31 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A | 826 | 112 | 17377 | 1707 |
CXCR5,PLA2G4A,DMXL2,PCSK1N,FLVCR2,AKAP5,GPR65,ATP8A1,MYO1B,PLXNA2,GATA3,ADD2,SPATS2L,SEZ6L2,LCP2,CA8,DDR1,NUDT12,KBTBD11,RAC3,EPDR1,CYP51A1,TUBB4A,MOK,COL22A1,SEC16B,GRHL1,SLC16A2,BCL6,PPP2R2B,SERPINH1,TLR4,GATM,NEB,RASGRP1,GLDC,CYP1B1,PGBD5,CD55,GAPDH,CAPN5,RNF125,PRKCQ,ATF3,ACVR2B,RAB38,DOCK5,ARHGEF26,SNCA,ENTPD1,ENPP1,KCNMB4,KLF12,GPR160,MAOA,ZBTB20,APBA2,MAPK10,COBL,FRMD5,CNTN1,MEF2C,BCL11B,NECAB2,CELSR1,PTPRD,CLGN,SLX1B,ISYNA1,COL27A1,HOPX,RASSF8,TTC1,MCOLN2,RNF180,RSL24D1,GPR155,MCF2L,PRELID2,ACTA2,CPXM2,LMAN2,KLF9,SMAD6,TSPAN9,ATP2B1,SNX7,GSTM2,LCA5,TBC1D8B,MGST3,DCHS1,SMARCD3,C3orf70,C4orf19,SLC46A3,AMDHD1,STEAP1,ILDR2,DKK1,CEBPB,TRIB3,DOCK7,RND3,CECR2,ACER2,GNAO1,AKT3,C1orf21,RAB31,DHCR7,DOCK6 |
| 2.471e-04 | -8.31 | MODULE_69 | MSigDB lists | MODULE_69 | 477 | 71 | 17377 | 1707 |
ACVR1,AASS,BEGAIN,GATA3,NDRG2,MAPK4,F3,BAG3,TYMP,PDE4D,SP140L,SOX21,KLHL4,AMIGO1,SAV1,SMAD3,SPNS1,ENPP1,CCBE1,ABI3,ALDOA,NCOA7,PLEKHG1,TNFSF4,RRAGD,PCSK5,MOCOS,SV2B,SLC25A27,PRDM8,SCD,HBE1,ISYNA1,USP30,SATB1,IL18R1,SYCP2,RALGPS2,SOAT2,DHRS12,IPCEF1,TBC1D9,FAR2,LRP3,MED12L,VEGFC,MSX1,SH3BP2,KDM5B,TBC1D8B,GSTM4,SDC3,OBSCN,WDR25,TTYH2,AGAP2,CCNG1,LHPP,PRDM1,RERE,GALNT3,DEXI,PCDHB7,CSF1,WDR19,DYNC2LI1,NXPH4,TNFRSF17,LARP1,PKIA,SLC43A1 |
| 2.485e-04 | -8.30 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN | 185 | 34 | 17377 | 1707 |
ARHGAP26,EHHADH,ST14,UBASH3B,CD276,MSR1,FAM198B,SEZ6L2,SPIRE1,MTUS1,CCDC120,RPS6KA2,ZNF438,SLC30A4,C1orf53,RAP2A,PRKG1,GSTM3,BEND4,SH3PXD2B,ESD,STXBP1,RAPGEF5,VAV3,EXOC6B,C3orf70,MFSD6,DCBLD2,AK1,LMLN,KPNA3,SLC2A6,SFMBT1,SFN |
| 2.485e-04 | -8.30 | GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN | MSigDB lists | GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN | 185 | 34 | 17377 | 1707 |
EML5,ST14,GRIK2,FZD8,CD7,ABHD6,EPB41L3,NAV1,UNC13B,CDC14B,ADCK1,TSPAN13,SCN2A,ZNF365,KIAA1549,SCN3A,RBMS2,NKX2-1,GCA,SH3BP2,SESN2,TBC1D8B,EXOC6B,ATOX1,TMEM200C,FEZ1,TNS1,TMEM74,BATF3,DOCK7,CDH17,DLG2,TNFRSF17,DISP2 |
| 2.485e-04 | -8.30 | GSE10325_CD4_TCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_MYELOID_UP | 185 | 34 | 17377 | 1707 |
BCL11B,TNIK,IL32,ENO2,RNF144A,ITGA6,GATA3,PRKCA,SATB1,BAG3,NELL2,TGFBR3,ALDOC,MYC,FHIT,MAST4,EVL,KLHL3,STAT4,SLC39A8,PRKCQ,CCNG1,SKAP1,FAM162A,PLEKHB1,SFXN1,DEXI,BEX4,AKT3,INPP4B,APBA2,TBC1D4,MLLT3,DOCK9 |
| 2.490e-04 | -8.30 | respiratory system development | biological process | GO:0060541 | 189 | 34 | 17256 | 1658 |
ID1,CELSR1,BMPR2,ASS1,CEBPA,SKI,FOXP2,RIDA,KCNAB1,SREBF1,LRP6,ERRFI1,SPRY2,PDGFRB,NKX2-1,GLI1,NOS3,YAP1,WNT11,ACVR2B,ZFPM2,SAV1,FGFR1,HEG1,MSC,EDA,PTK7,CCBE1,DISP1,BMP4,BMPR1A,NKX2-8,DHCR7,FOXA1 |
| 2.507e-04 | -8.29 | WANG_SMARCE1_TARGETS_DN | MSigDB lists | WANG_SMARCE1_TARGETS_DN | 347 | 55 | 17377 | 1707 |
PPP4R4,DOCK1,RBFOX2,RGS20,ISYNA1,FAM198B,KBTBD11,TPD52L1,PRR7,MOK,SYCP2,KIAA0895,HMGCS1,ABI3BP,TACC2,SLC16A2,STC2,MAGEA3,OPN3,SGK1,STEAP3,BNIP3,TSPAN13,MAGEA6,RRAS2,PRR16,CAND2,TMEM56,ATP2B1,CYP1B1,PRAME,BDNF,SLC39A8,FGF12,DUSP9,SLITRK5,SHISA2,TMEM47,ZFPM2,GALNT14,CENPV,SFXN1,TRIM9,MAGEA12,PDLIM3,HPSE,PLAGL1,PLK2,HK2,INPP4B,SEMA3C,TPM1,TBC1D4,MID1,SIX2 |
| 2.538e-04 | -8.28 | V$MMEF2_Q6 | MSigDB lists | V$MMEF2_Q6 | 253 | 43 | 17377 | 1707 |
TYRO3,ARHGAP26,MXI1,INPPL1,RUNX2,FGF13,RHOBTB1,GCAT,LMCD1,BEGAIN,IKZF2,NEDD4,RTN1,GPR15,FOXP2,ATXN7L1,CHN2,FLRT3,GAN,HS3ST5,MYO3B,BCL6,ACVR2A,PPP2R2B,TSPAN9,RIMS2,SSH3,USP2,GAPDH,PRDM13,TCEA3,PACSIN3,PRKCQ,ASPH,MBNL2,DKK1,IFT81,GYPC,KPNA3,GNB4,DLG2,SEMA3A,FILIP1 |
| 2.543e-04 | -8.28 | TGCACTG,MIR-148A,MIR-152,MIR-148B | MSigDB lists | TGCACTG,MIR-148A,MIR-152,MIR-148B | 284 | 47 | 17377 | 1707 |
EFNB2,ACVR1,RUNX2,ROBO2,LDLR,OTX1,HECW2,CANX,KIAA1217,DNER,TRPS1,LRRC55,CNTN4,SLC7A11,AKAP7,MPPED2,MARCH3,PRICKLE2,ERRFI1,MED12L,MOB1B,BCL7A,PCDH10,GPM6A,TGFA,ESRRG,ANK2,CYTH3,KIAA1324L,STRADB,MAFB,PHACTR2,ZFPM2,RNF44,BCL11A,DYRK1B,ARHGAP21,GPRC5B,RNF217,BACH2,FBN1,CSF1,BMP1,PPARGC1A,NRP1,DOCK6,SNPH |
| 2.576e-04 | -8.26 | heart valve development | biological process | GO:0003170 | 40 | 12 | 17256 | 1658 |
ACVR1,BMPR2,HEYL,DCHS1,GATA3,PRDM1,BMPR1A,BMP4,SMAD6,SHOX2,HEY1,MEF2C |
| 2.580e-04 | -8.26 | GAIN | pfam domains | PF16489 | 11 | 6 | 17054 | 1666 |
ADGRB3,CELSR1,CELSR3,ADGRL2,ADGRB2,ADGRL1 |
| 2.596e-04 | -8.26 | actin cytoskeleton | cellular component | GO:0015629 | 487 | 70 | 18223 | 1724 |
CGN,SORBS1,TMSB15A,MYO1B,ADD2,RAC3,PPP1R9A,CTNNA2,PLS3,SCIN,MYO3B,POF1B,MYH15,RTKN2,MARCKS,CTTN,TLN2,MYRIP,NEB,DBN1,FER,MYLK3,DSTN,CAP2,NPM3,ROR1,INTS6,SNCA,GSN,ARHGAP21,WIPF3,GBP1,ALDOA,TMOD2,TPM1,COBL,MYO1D,GNG12,OPHN1,TJP1,FHOD3,ABLIM1,GAS2L3,SMTN,ACTA2,SH3PXD2B,MYO6,ULBP1,PDLIM7,PAK1,SYNPO2,RHOQ,PXN,MYO10,HIP1,FERMT2,PLS1,CDC42BPA,CTTNBP2NL,ARHGAP32,PALLD,PEAK1,BAIAP2,FGR,PLEKHH2,MYADM,SVIL,MYOM2,CDH2,FILIP1 |
| 2.618e-04 | -8.25 | GAIN_dom_N | interpro domains | IPR032471 | 11 | 6 | 18492 | 1811 |
ADGRB3,CELSR1,CELSR3,ADGRL2,ADGRB2,ADGRL1 |
| 2.648e-04 | -8.24 | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | MSigDB lists | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | 193 | 35 | 17377 | 1707 |
FAM171B,MOCOS,ZSWIM5,ZHX3,SEC24D,COBLL1,OVOL2,CHSY1,IKZF2,TSPAN17,PLS3,EPCAM,GPR15,KAZN,NBEA,TRPC1,TMEM37,MED7,B4GALT6,DUSP1,DPYSL5,CRIP2,HIP1,TBC1D16,KHDRBS2,CAMK2N1,GALNT3,HLF,PTPRJ,HPSE,ERN1,MAP9,FBXO27,COBL,CSRP2 |
| 2.649e-04 | -8.24 | regulation of protein metabolic process | biological process | GO:0051246 | 2752 | 315 | 17256 | 1658 |
ACVR1,PPP4R4,DUSP8,GRIK2,RECK,DNAJC3,LDLR,GATA3,NPM1,STAT5B,CEBPA,CHAC1,PRKCA,SNX9,STK24,NOS1AP,SKI,PPP1R26,TGFBR3,PMAIP1,ZFYVE28,CFHR1,RAP2A,PPP2R2B,RCAN3,EIF4E3,ACVR1C,TGFA,LRRK2,DEPTOR,AGO4,PRKAR2B,ACVR2B,F12,ENPP1,SH3RF1,NCKAP1L,CCBE1,PLK2,BBC3,SERPINI1,INPP5F,DIRAS1,SPRY4,NRP1,SPOCK3,LATS2,SLK,DHCR24,OPHN1,BTBD9,TNFRSF10C,TNFRSF19,GAS1,RPL13A,MECOM,FRY,PAIP2B,BACE2,MYC,FLRT3,C1QL4,PRELID1,SREBF1,PRR16,ZNF385A,HMGCR,BOD1,RPL26,VLDLR,PACSIN3,HIP1,C1R,ARRDC4,PLCB1,FAM162A,CPEB1,BEX4,PMEPA1,PELI2,THBS4,INHBE,LAPTM4B,CDH2,SMYD3,EPHA3,MTG1,PCSK1N,RNF144A,C4A,LCP2,DDR1,TLR3,DACT1,CNKSR3,MAGEA3,DAB2IP,PDE4D,SERPINH1,PERP,FZD1,GAPDH,NECAB1,FZD4,PREX1,ADCY1,ATF3,PRKCQ,WNT11,PXYLP1,ASPH,FGFR1,MAGI3,SNCA,CXCL10,BEX3,WFS1,APELA,PEMT,WWTR1,MAP3K21,TNFSF15,BMPR1A,ATG5,MAPK10,MID1,EDA2R,CD276,FZD8,IPO5,UBAC2,HERC5,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,NEDD4,GSAP,GHR,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,ZFP36L2,PARP9,VEGFC,RAPGEF2,GAREM1,RACK1,GPLD1,CEBPB,PTPRC,TRIB3,NSD1,FGR,XBP1,BMP4,LRRK1,ATP2B4,LARP1,BTRC,PHACTR3,ACSL1,FGF13,NDRG2,LILRB1,GSDME,F3,PPM1E,ITGB3,PCOLCE2,EPHB6,ENO1,TLR4,SLIT2,PDGFRB,RASGRP1,PRKACB,LAMP3,TNK2,CD55,ATF4,GCNT2,SESN2,COL4A3,CR2,ROR1,INHBC,GSN,GPRC5B,ERN1,C8orf88,TNFRSF1A,NCOA7,PPARGC1A,MAGI2,CACUL1,PRKAA2,TYRO3,LONRF1,FN1,UBASH3B,JDP2,FBXO4,SORBS3,PFN2,SPINK5,DDIT4,RNF180,EEF2,IGF1R,GATA2,LRP6,ADCY6,INAVA,PAK1,FGFR4,ATP5IF1,MSTN,EFNA3,WWC1,STRADB,DUSP9,PDE8A,HERPUD1,MAPKAPK2,CSF1,SEMA3A,TESC,SFN,PRKN,AVPI1,NEK10,ID1,CFH,IL15,CELSR3,HECW2,NTRK3,TNKS1BP1,PIBF1,PPP1R9A,RIDA,CDC14B,BCL6,ACVR2A,FHIT,PROS1,MET,HSPA2,IGFBP3,ALG10B,FER,CSN2,NOP53,PTPN6,ACO1,RNF125,VIM,SYNJ2BP,RARRES2,CD40,C4BPB,WARS,SMAD3,CAMK2N1,NRG3,PTPRJ,RNF217,EIF4EBP1,GBP1,ITGA2,DUSP19,HGF,SUSD4,CNTN1,TENM1,TNIK,NECAB2,BMPR2,PAK5,APBB1,LRP4,IGF2BP2,BMP6,PPP2R3A,MAP1A,PRKCD,RASD2,EIF1,AFAP1L2,IQGAP3,TNFRSF11A,SYK,DUSP1,MOB1B,CRIM1,PRICKLE1,PHACTR2,AGAP2,CCNG1,TLR6,MGMT,CTIF,DKK1,GPR37,DOCK7,MYADM,MAP2K6,ACER2,MAP3K20,PKIA |
| 2.662e-04 | -8.23 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_UP | 171 | 32 | 17377 | 1707 |
RGS16,ACSL1,ELOVL7,OPHN1,ATP6V1E2,DENND3,UBTD2,EYA4,F3,MCOLN2,MAP7,MET,TBC1D9,PRR16,SMPDL3A,KIAA1211,MYO10,AGPAT4,GJB2,TGFA,STAT4,AK4,BATF,SAV1,BATF3,AKT3,MFSD2A,SVIL,TNFSF15,HS3ST3B1,SLC16A10,HEY1 |
| 2.662e-04 | -8.23 | AKT_UP_MTOR_DN.V1_UP | MSigDB lists | AKT_UP_MTOR_DN.V1_UP | 171 | 32 | 17377 | 1707 |
EFNB2,MAN2B2,PAK1,CD55,DUSP8,SLC39A8,C3orf52,DHCR24,MSR1,PACSIN3,AK4,ATF3,RASD1,ARRDC4,RIMKLB,PTPRJ,IGF1R,PLAGL1,BACE2,PLK2,PDE10A,ALDOC,MPP2,CLMN,SH3BGRL2,SUSD4,CPE,DHCR7,TESC,TMEM56,DUSP1,GLDC |
| 2.662e-04 | -8.23 | GO_REGULATION_OF_OSSIFICATION | MSigDB lists | GO_REGULATION_OF_OSSIFICATION | 171 | 32 | 17377 | 1707 |
PLA2G4A,INTU,PDLIM7,TRPM4,ACVR1,ID1,RUNX2,BMPR2,ZHX3,CD276,LRP4,CEBPA,ACVR2B,CHSY1,BMP6,FGFR1,SKI,CEBPB,SMAD3,ID3,ENPP1,CSF1,TFAP2A,ACVR2A,HGF,BMP4,BMPR1A,SIX2,SNAI2,GLI1,MEF2C,FZD1 |
| 2.668e-04 | -8.23 | ST8SIA4 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4) | protein interactions | 7903 | 67 | 17 | 17029 | 1718 |
TMEM67,MRC2,TCTN2,ITPRIP,CNTNAP3,PLXNA2,AMIGO1,CACHD1,TGFBR3,BACE2,FRAS1,FAT1,LRP6,ACTA2,NRP1,NCAM1,GALNT18 |
| 2.672e-04 | -8.23 | cellular response to stimulus | biological process | GO:0051716 | 6466 | 687 | 17256 | 1658 |
ARHGAP26,PDE1B,GRIK2,DNAJC3,NPM1,CEBPA,STAT5B,CHAC1,DOCK3,CA8,EYA4,TXNDC5,SKI,BAG3,FBXO32,TGFBR3,PMAIP1,RAP2A,RAB26,TSHR,CPE,SMAD9,DCC,CAP2,WLS,TGFA,LRRK2,FEZ1,PRKAR2B,ABCC2,FGF17,INTS6,PYCR1,ENPP1,WIPF3,ADRB1,ARHGAP28,BBC3,ERCC5,DIRAS1,INPP5F,TPM1,MEF2C,LATS2,SCN5A,GNG12,CYP2J2,ITGA6,SLK,TJP1,GPSM2,HPCAL4,CHN1,APLF,FLRT3,SRGAP1,CADPS2,ST8SIA1,NCAM1,STXBP1,TSPAN9,GFRA1,CHRM3,LRP12,ZNF385A,FADS1,BDNF,MYO10,STAT4,MGST3,ARID5B,EFHC2,FASN,FHL2,HIP1,CALCRL,RYR2,OR11H4,ARRDC4,CPEB1,TEX15,SH3GL2,GSTO2,CDH17,INHBE,TRPC3,SHTN1,DOCK9,BTC,ZNF516,IL13RA1,MAPK4,GRK6,NRXN1,LCP2,CDS1,TXNRD3,GPR15,PLPP1,TLR3,CHRNA5,KMO,DACT1,CNKSR3,RTKN2,RAB27B,SNX10,PERP,DOCK8,FZD1,MYLK3,GAPDH,ADM2,FZD4,KCNH5,ADCY1,WNT11,RAB38,FGFR1,MAGI3,GABARAPL1,IRS2,ARHGAP21,CXCL10,GPR160,WFS1,APELA,WWTR1,INPP4B,TNFSF15,HOXB9,LRRC27,RAB30,CGB2,EDA2R,ROBO2,FZD8,ESRP1,CD276,IPO5,CBS,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,TSPAN17,NEO1,HMGCS1,MCF2L,BHLHA15,PCBP4,GHR,MYO6,ZFP36L2,FES,PARP9,VEGFC,TRPM4,B9D1,RAB6B,RAPGEF2,RASA3,GAREM1,RACK1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,AKT3,GNAO1,XBP1,NEK11,BMP4,CMPK2,DOCK6,FOXA1,BTRC,ATP2B4,FGF13,LILRB1,ASS1,NDRG2,ITPR2,FAM13A,RND2,CPNE2,RPS6KA2,ITGB3,TBC1D32,TLR4,RAPGEF5,ITGB7,KCNIP3,GCNT2,MARK1,ATF4,COL4A3,ANK2,NFE2L1,PLPP2,CR2,PLEKHA1,BATF,SESN1,PLEKHB1,TSKU,SPNS1,INHBC,TCF7L1,INSIG1,MAP2,GNB4,ERN1,TNFRSF1A,PIK3C2B,ADGRA3,ADGRL2,CACUL1,RRAGD,TYRO3,PRKAA2,RGS16,RUNX2,LGALS3,UBASH3B,RASL11B,MLC1,IL18R1,DOK5,EFEMP1,NUMBL,ZBTB38,IGF1R,SEMA4F,BCHE,PDE10A,LRP6,ADCY6,BNIP3,PAK1,DPYSL5,FGFR4,UNC5C,BTNL9,HOMER2,EFNA3,STRADB,OBSCN,PDE8A,GPR19,BAIAP2,MAPKAPK2,GRIK4,HEYL,CSF1,PLD1,SEMA3A,TESC,SFN,MME,PRKN,ID1,DOCK1,AKAP5,RBFOX2,RHPN2,OR51B4,NTRK3,TNKS1BP1,RADIL,PCLO,SEMA6A,PPP1R9A,CYP26A1,SLC22A17,BCL6,ADGRL1,EEPD1,SCN2A,SNAI2,GLI1,CTH,TMEM67,EVL,UROS,NOP53,LRRC8B,FGF12,CHRNA6,VIM,GSTO1,FRK,JAM3,SMAD3,NRG3,PTPRJ,PTK7,GBP1,ITGA2,MAOA,HGF,CTNND2,HEY1,CNTN1,TENM1,LPAR2,IL32,BMPR2,PAK5,GRB14,NLRP14,APBB1,MCTP2,GABRG2,RASD1,ARHGAP44,RASD2,GTF2F2,TFAP2A,SGK1,PRICKLE2,TSPAN13,KLF9,PCK2,ESD,SYK,ATP2B1,CES3,DUSP1,MOB1B,FOXN3,NUGGC,NUAK2,LITAF,FERMT2,PRICKLE1,MGMT,HOMER3,DKK1,CD37,DDAH1,DOCK7,FAT4,FBN1,DLG2,PAX9,SLC1A5,TBC1D4,PTGES,KIF1B,CACNA2D1,CGN,ACVR1,LANCL3,LGR4,LDLR,GATA3,PRKCA,RAC3,AARS,NCS1,STK24,MOK,CHRDL1,ATRNL1,GSTM3,RCAN3,GLDC,GDAP1,DCDC1,ACVR1C,WISP3,NR6A1,DEPTOR,BNIP3L,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,GNAI1,GPR150,AHRR,NCKAP1L,RASGRF2,PLK2,SEMA3C,MAPK13,NRP1,UNC5B,SPOCK3,EFNB2,INPPL1,MRC2,ALOX5AP,CELSR1,PTPRD,GABRB2,DHCR24,OPHN1,TNFRSF10C,ADSSL1,TNFRSF19,GAS1,RPL13A,RALGPS2,PIK3AP1,MYC,SREBF1,PRKG1,OPN3,GRIP1,TSPAN12,MAST4,GPR161,RIMS2,IGSF3,RNF152,PTCH2,EPB41L5,RPL26,DISC1,DCHS1,RAPGEF4,VLDLR,NSD2,CDC42BPA,PLCB1,FAM162A,DAGLA,PMEPA1,PKN3,PELI2,THBS4,WDR19,MATN2,MPP2,SMYD3,EPHA3,PLA2G4A,PCSK1N,AMOTL1,RASAL2,TCTN2,RHOD,GPR65,PLXNA2,CHUK,DDR1,ZFYVE9,TIAM2,ASNS,SHF,DAB2IP,PDE4D,GAB2,PDK1,PREX1,SATB2,ATF3,PRKCQ,ATOH1,PYGO1,ATP1B1,PATJ,DCBLD2,SNCA,ISG20,HTR7,BEX3,PRKCB,ASIC1,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,ATG5,MAPK10,NR3C2,MID1,HACE1,PLSCR4,IGFBP6,EPS8,GPR180,GABRR2,NDFIP2,RGS7,INPP1,NEDD4,ADGRB2,RASSF8,GPR155,SGK3,PRKG2,ERRFI1,YBX3,SMAD6,GFI1,SPRY2,VAV3,SLC40A1,SH3BP2,ARHGEF28,GSTM2,ARAP2,PXN,PTPN13,MPP1,GUCY1A2,SKAP1,GPLD1,CEBPB,FGR,OR2T33,TERT,PCGF2,MCC,TUFT1,GRIN2D,LRRK1,TNFRSF17,CERS1,OCLN,DDIT3,LARP1,ATP1A3,ACSL1,HEBP1,DNER,RBM11,KREMEN1,GSDME,F3,ARHGEF10L,EPCAM,PPM1E,PCOLCE2,EPHB6,OR2W3,SLIT2,IL1RAP,PRKACB,PDGFRB,RASGRP1,CYP1B1,TNK2,SESN2,SKAP2,CAPN5,YAP1,ROR1,SGK2,GRK3,SERGEF,GSN,GPRC5B,OXTR,PPARGC1A,TNFSF4,MAGI2,GPR63,BCL11B,FN1,RHOBTB1,FBXO4,ATP6V1E2,CD7,PHGDH,ADGRG6,DDIT4,EEF2,CA2,INAVA,NCEH1,CEBPD,NOS3,ATP5IF1,IL17RD,GPR176,RHOQ,MSTN,SH2D2A,GSTM4,EDEM3,DUSP9,WWC1,HERPUD1,RIPOR2,PLAGL1,ADGRB3,SH3BP4,RAB31,HK2,TMEM117,PTPRN2,NXPH4,DISP2,CREB3L2,CXCR5,SORBS1,IL15,CELSR3,ARHGAP22,CANX,DOCK2,CD53,UNC13B,PDZD8,CDC14B,RPS6KL1,ACVR2A,GULP1,FHIT,MET,HSPA2,FER,ANTXR2,PTPRU,PTPN6,SYNJ2BP,CD40,DOCK5,BCL11A,MSC,TRIM34,EIF4EBP1,RGS10,FAAP20,CYP2U1,DISP1,LIFR,MAST1,OR51B5,TNIK,ARHGEF11,TSPAN15,REL,LRP4,TNFSF13B,COL4A5,SLX1B,NOTUM,BMP6,SYDE2,MCU,NKX6-1,RAB11FIP5,CHN2,PRKCD,STC2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,MSX1,RAB3B,KDM5B,HNF4G,CRIM1,NR4A1,ESRRG,GRID1,MARS,ARHGAP32,TLR6,LRAT,LEPR,GPR37,TIFA,EDA,RND3,MAP2K6,ACER2,CTSV,UACA,GEM,MAP3K20,IL9R,NPHP1,ABCG1 |
| 2.676e-04 | -8.23 | Nucleotide-diphossugar_trans | interpro domains | IPR029044 | 88 | 20 | 18492 | 1811 |
CHSY3,GXYLT2,B3GALT1,B3GLCT,GALNT6,GALNT12,COLGALT2,GALNT17,GALNT13,CHSY1,GALNT14,B4GALNT3,GALNT3,GALNT1,GBGT1,PLOD2,MGAT1,GALNT18,B4GALT7,B4GALT6 |
| 2.694e-04 | -8.22 | negative regulation of phosphorylation | biological process | GO:0042326 | 472 | 69 | 17256 | 1658 |
PRKN,DUSP8,DNAJC3,NPM1,NDRG2,CEBPA,NTRK3,PIBF1,PPM1E,ZFYVE28,CNKSR3,DACT1,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,PTPN6,LRRK2,PREX1,DEPTOR,ATF3,PRKAR2B,SYNJ2BP,SNCA,WARS,CAMK2N1,IRS2,ENPP1,PTPRJ,GBP1,WWTR1,DUSP19,HGF,INPP5F,GRB10,SPRY4,PPARGC1A,LATS2,UBASH3B,IPO5,PKN1,DDIT4,MECOM,IGF1R,FLRT3,MYC,C1QL4,PRKCD,LRP6,ERRFI1,SMAD6,SPRY2,DUSP1,HMGCR,MSTN,DUSP9,RACK1,DKK1,PTPRC,TRIB3,MYADM,PMEPA1,LRRK1,BMP4,TESC,SMYD3,PKIA,SFN |
| 2.697e-04 | -8.22 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | 520 | 76 | 17377 | 1707 |
CREB3L2,EXPH5,TRIM2,UGT8,SCAMP1,UGDH,ASS1,COBLL1,ABAT,PRKCA,KBTBD11,QPRT,CDS1,PLS3,EPCAM,EPB41L3,GULP1,GATM,CTH,GLDC,SLC3A2,ABCC4,DSTN,ANK2,CAP2,SHANK2,ACO1,ABCC2,DSP,GABARAPL1,SLC39A14,WWTR1,MAOA,HPGD,GRB10,SERPINI1,NR3C2,MXI1,EHHADH,RHOBTB1,GRB14,PTPRD,ITGA6,EPS8,PFN2,PPP2R3A,KIAA0895,CA2,IGF1R,MSMO1,TSC22D1,BNIP3,MPDZ,MYO6,PCK2,RRAS2,AGL,ESD,SMPDL3A,IGSF3,USP2,ALDH2,PNP,SLC27A2,ESRRG,COL4A4,AK4,PDE8A,CDC42BPA,FNDC3A,BEX4,FAT1,FNBP1L,OCLN,MME,ACSM3 |
| 2.709e-04 | -8.21 | central_nervous_system-brainstem-glioma | COSMIC cancer mutations | central_nervous_system-brainstem-glioma | 350 | 55 | 17385 | 1698 |
CREB3L2,GXYLT2,LPAR2,MRC2,ACVR1,PTPRD,ITGA6,PLXNA2,NKAIN2,HBE1,WDFY4,TNFRSF19,HMCN1,TIAM2,SLC35F1,RGS17,EPB41L3,ZBTB38,ABCA5,COL25A1,FRAS1,PPFIA2,SLC10A7,CHRDL1,MPPED2,GRIP1,CADPS2,FHIT,MET,MYRIP,KLHL29,TSHR,TMC7,ARAP2,THSD4,ESRRG,ACO1,CHRNA6,SATB2,ROR1,SNAP25,GUCY1A2,NAALADL2,FGFR1,MMP15,DDAH1,FBN1,TMEM117,PTPRN2,HGF,CDH2,KIF1B,SPOCK3,NPHP1,MME |
| 2.709e-04 | -8.21 | cellular response to growth factor stimulus | biological process | GO:0071363 | 489 | 71 | 17256 | 1658 |
CGN,ID1,ACVR1,RBFOX2,GATA3,NTRK3,STAT5B,ZFYVE9,SKI,TGFBR3,CHRDL1,ACVR2A,DAB2IP,SNAI2,PDGFRB,GCNT2,SMAD9,FGF12,FEZ1,FGF17,ACVR2B,FGFR1,SNCA,SMAD3,ERN1,HPGD,HGF,BMPR1A,NRP1,PPARGC1A,MAGI2,MEF2C,RUNX2,BMPR2,ESRP1,LRP4,GAS6,BMP6,GAS1,DDIT4,EEF2,FLRT3,GTF2F2,ERRFI1,SMAD6,ZFP36L2,FGFR4,EPB41L5,BDNF,MSX1,PXN,KDM5B,MSTN,NR4A1,RAPGEF2,RYR2,FERMT2,GAREM1,MARS,PDE8A,RACK1,BAIAP2,MAPKAPK2,GALNT3,FAT4,SH3GL2,FBN1,HEYL,PAX9,BMP4,KIF1B |
| 2.715e-04 | -8.21 | secondary alcohol metabolic process | biological process | GO:1902652 | 117 | 24 | 17256 | 1658 |
PRKAA2,MVK,MVD,LDLR,VLDLR,DHCR24,NFE2L1,CEBPA,NPC2,LEPR,FGFR1,CYP51A1,IDI1,ERG28,HMGCS1,INSIG1,SOAT2,MSMO1,OSBPL5,SREBF1,SQLE,DHCR7,ABCG1,HMGCR |
| 2.717e-04 | -8.21 | GATAAGR_V$GATA_C | MSigDB lists | GATAAGR_V$GATA_C | 277 | 46 | 17377 | 1707 |
ENO2,ZHX3,CHCHD7,PLAG1,ISYNA1,CREB5,GRK6,SATB1,TNFRSF19,BMP6,RPL13A,PPP2R3A,MECOM,MCU,TRPS1,ADPRHL1,PPM1E,HMGCS1,GPR155,FLRT3,LHX6,HS3ST5,TSPAN12,FIGN,ETV1,MYT1,GATM,TNK2,MEIS2,FZD4,KCNH5,NFIA,FHL2,PTPRC,ADAMTS3,FMO4,ALDOA,B3GALT2,SPRY4,PPARGC1A,MLLT3,MID1,STON2,BTRC,PKIA,MEF2C |
| 2.729e-04 | -8.21 | metal ion transmembrane transporter activity | molecular function | GO:0046873 | 457 | 68 | 17224 | 1680 |
CACNG3,GRIK2,MCOLN3,ITPR2,CACNB4,SLC9A7,NCS1,KCNAB1,KCNN2,KCNS3,TRPC1,CNNM2,TMEM37,SCN2A,FAM155B,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,SLC9C1,SLC39A8,KCNH5,ATOX1,JPH1,SLC25A28,KCND3,ATP1B1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,SCN5A,SLC6A9,SCN8A,SLC1A3,SLC12A6,GAS6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,CACNB2,KCNMB3,SLC6A15,NIPAL2,FAM155A,ATP2B1,TRPM4,SLC40A1,KCNQ3,CACNA1E,RASA3,RYR2,GRIK4,KCNK15,GRIN2D,TRPC3,CACNA2D1,ATP2B4,ATP1A3 |
| 2.755e-04 | -8.20 | MODULE_432 | MSigDB lists | MODULE_432 | 15 | 7 | 17377 | 1707 |
SQLE,MVK,IDI1,HMGCS1,DHCR7,MVD,HMGCR |
| 2.755e-04 | -8.20 | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | MSigDB lists | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | 15 | 7 | 17377 | 1707 |
MARCKS,MOXD1,MSTN,PLK2,ZFP36L2,ATP2B4,IGFBP3 |
| 2.758e-04 | -8.20 | limb development | biological process | GO:0060173 | 175 | 32 | 17256 | 1658 |
RUNX2,BMPR2,RECK,ITGA6,LRP4,PLXNA2,ZNF219,KREMEN1,SP8,SKI,FRAS1,DLX6,TBC1D32,TFAP2A,LRP6,DYNC2H1,B9D1,INTU,RAX,MSX1,ASPH,FGFR1,DKK1,WDR19,PAM,HOXD13,SEMA3C,BMP4,BMPR1A,SHOX2,MAP3K20,PCSK5 |
| 2.758e-04 | -8.20 | appendage development | biological process | GO:0048736 | 175 | 32 | 17256 | 1658 |
RUNX2,BMPR2,RECK,ITGA6,LRP4,PLXNA2,ZNF219,KREMEN1,SP8,SKI,FRAS1,DLX6,TBC1D32,TFAP2A,LRP6,DYNC2H1,B9D1,INTU,RAX,MSX1,ASPH,FGFR1,DKK1,WDR19,PAM,HOXD13,SEMA3C,BMP4,BMPR1A,SHOX2,MAP3K20,PCSK5 |
| 2.759e-04 | -8.20 | GO_STEM_CELL_DIFFERENTIATION | MSigDB lists | GO_STEM_CELL_DIFFERENTIATION | 186 | 34 | 17377 | 1707 |
SEMA6B,ACVR1,RUNX2,OVOL2,SEMA6A,EPCAM,TGFBR3,SEMA4F,EOMES,BCHE,LRP6,SNAI2,SEMA6C,FZD1,EPB41L5,MSX1,GPM6A,SOX21,WNT11,BATF,FGFR1,PTPRC,HEYL,WWTR1,HGF,SEMA3C,BMPR1A,BMP4,NRP1,SEMA3A,FOXA1,SIX2,HEY1,MEF2C |
| 2.763e-04 | -8.19 | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | MSigDB lists | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | 454 | 68 | 17377 | 1707 |
TRIM2,ACSL1,GRIK2,RECK,CNTNAP3,ADAMTS6,ENAH,NRXN1,NOVA1,CCNJ,CPNE2,ABI3BP,ACVR2A,DPP10,RNF145,NR6A1,ADCY1,ATP1B1,MFSD6,BCL11A,IRS2,TRIM9,HLF,BACH2,PAM,GRB10,SPRY4,ATG5,MBOAT2,LPP,LONRF1,BMPR2,ROBO2,TBC1D1,PLAG1,IPO5,ZIC2,IGF2BP2,SPIRE1,LRRN1,MAP1A,CNTN4,CACNB2,PRKCD,TRIM3,TOX,FIGN,NPTXR,SEPT3,FMNL2,ATP2B1,LRP12,SLITRK2,CRIM1,PLS1,CDC42BPA,CTTNBP2NL,PALLD,FNDC3A,MBNL2,BAIAP2,MAP1B,NEGR1,DOCK7,AKT3,PCGF2,TBC1D4,SIX2 |
| 2.779e-04 | -8.19 | GO_ENDOTHELIUM_DEVELOPMENT | MSigDB lists | GO_ENDOTHELIUM_DEVELOPMENT | 88 | 20 | 17377 | 1707 |
SLC40A1,ACVR1,ID1,BMPR2,RAPGEF2,COL18A1,TJP1,ACVR2B,OVOL2,ARHGEF26,HEG1,MYADM,MARVELD2,GSTM3,PTPRS,PDE4D,BMP4,NRP1,MET,HEY1 |
| 2.782e-04 | -8.19 | SH3_2 | pfam domains | PF07653 | 57 | 15 | 17054 | 1666 |
VAV3,SORBS1,SH3GL2,MPP7,RUSC2,MPP1,MCF2L,ZDHHC6,SHANK2,SH3BP4,MPP2,DLG2,TJP1,SH3PXD2B,DOCK3 |
| 2.788e-04 | -8.19 | enzyme binding | molecular function | GO:0019899 | 2219 | 263 | 17224 | 1680 |
DNAJC3,LDLR,NPM1,CEBPA,CTBP2,DOCK3,PRKCA,SNX9,RAC3,NOS1AP,SKI,PPP1R26,SLC22A18,GSTM3,RCAN3,NKX2-1,TBC1D8,CAP2,LRRK2,MEF2B,PRKAR2B,FGF17,ARHGEF26,CCBE1,RASGRF2,ADRB1,BBC3,DIRAS1,NRP1,SPART,MEF2C,SCN5A,EHHADH,TBC1D1,DHCR24,BTBD9,RALGPS2,SREBF1,SRGAP1,DENND1C,NCAM1,STXBP1,FMNL2,GFRA1,RIMS2,RNF152,BOD1,TBC1D8B,RAPGEF4,RYR2,PEX5L,NPC2,PLCB1,BEX4,PKN3,LAPTM4B,IQSEC2,CDH2,SMYD3,DOCK9,EPHA3,BTC,DNM3,RHOD,RNF144A,PKP2,ADD2,MAPK4,DDR1,TBC1D30,TIAM2,DACT1,MAGEA3,NBEA,DAB2IP,RTKN2,MARCKS,PDE4D,JAKMIP3,SNX10,DOCK8,GAB2,FZD4,PFKFB2,PREX1,ATP1B1,DSP,TTC28,TBC1D16,FGFR1,GABARAPL1,IRS2,PRKCB,WFS1,PLEKHG1,MAP3K21,MID1,HACE1,DENND5B,PLSCR4,FARP1,FZD8,BACE1,EPS8,IPO5,CBS,PSD3,GAS6,PKN1,EPHB1,TSPAN17,NEDD4,MCF2L,GHR,TBC1D9,YBX3,ERRFI1,SMAD6,SPRY2,PARP9,VAV3,ARHGEF28,GSTM2,ARAP2,MCF2L2,RAPGEF2,RACK1,CTTNBP2NL,SKAP1,PTPRC,CEBPB,TRIB3,FGR,MYOM2,GRIN2D,DOCK6,ATP2B4,PHACTR3,EXPH5,LILRB1,ABAT,F3,RND2,ADPRHL1,ARHGEF10L,HPS1,AKAP7,ITGB3,JAKMIP2,EPHB6,ENO1,MYRIP,RAPGEF5,IL1RAP,PDGFRB,PRKACB,RASGRP1,TNK2,ATF4,ANK2,ROR1,COTL1,TCERG1L,SERGEF,GPRC5B,ERN1,PPARGC1A,MAGI2,CACUL1,FRMD5,RRAGD,LONRF1,TYRO3,FN1,STXBP5L,RHOBTB1,STXBP6,RNF180,IGF1R,EEF2,BCHE,ADCY6,BNIP3,FBXL2,FGFR4,PAK1,ATP5IF1,RHOQ,SLC27A2,GSTM4,SPATA13,WWC1,OBSCN,PDE8A,PRDM1,TBC1D2,MAPKAPK2,SH3BP4,FNBP1L,SFN,DMXL2,PRKN,AKAP5,DOCK1,NTRK3,DENND3,TNKS1BP1,DOCK2,PPP1R9A,UNC13B,FHIT,WWC2,MET,HSPA2,FER,PTPN6,RNF125,CD40,DOCK5,WARS,CAMK2N1,SMAD3,RANBP2,PTPRJ,NRG3,RNF217,GBP1,DUSP19,HGF,ARFGEF3,KIZ,TSPAN15,PAK5,GRB14,ARHGEF11,RUSC2,LRP4,SELL,ARHGAP44,RAB11FIP5,STC2,PRKCD,RASD2,ACTA2,IQGAP3,SYK,MOB1B,PPP1R3D,RIN2,USP2,CYTH3,ASAP3,AGAP2,GPR37,DOCK7,NACC2,GCSAM,RND3,MAP2K6,DLG2,TBC1D4,PKIA,STOM |
| 2.789e-04 | -8.18 | cardiac muscle cell action potential | biological process | GO:0086001 | 46 | 13 | 17256 | 1658 |
TRPM4,SCN5A,KCNN2,SCN1B,CACNB2,ANK2,FGF12,RYR2,PKP2,KCND3,ATP1B1,CACNA2D1,GJC1 |
| 2.799e-04 | -8.18 | potassium channel complex | cellular component | GO:0034705 | 98 | 21 | 18223 | 1724 |
DPP10,KCNV1,KCNIP3,KCNQ3,GRIK2,AMIGO1,KCND3,SNAP25,KCNC4,NOS1AP,LRRC55,KCNJ4,GRIK4,KCNMB4,KCNAB1,KCNG1,KCNMB3,KCNS3,DLG2,CTTN,KCNB2 |
| 2.801e-04 | -8.18 | GO_REGULATION_OF_HEART_CONTRACTION | MSigDB lists | GO_REGULATION_OF_HEART_CONTRACTION | 216 | 38 | 17377 | 1707 |
SCN5A,CACNG3,BVES,CYP2J2,PKP2,ITPR2,CACNB4,NOS1AP,HOPX,KCNJ4,SCN1B,CACNB2,DSG2,SREBF1,TRPC1,PDE4D,ATP2B1,NOS3,TRPM4,KCNIP3,GSTM2,TMEM65,ANK2,RYR2,GSTO1,ATP1B1,KCND3,ASPH,DSP,GJC1,KCNK15,GNAO1,ADRB1,TPM1,SEMA3A,CACNA2D1,ATP2B4,ATP1A3 |
| 2.801e-04 | -8.18 | protein kinase activity | molecular function | GO:0004672 | 652 | 91 | 17224 | 1680 |
EPHA3,BTC,NEK10,ACVR1,CHUK,NTRK3,MAPK4,STAT5B,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,RPS6KA2,TGFBR3,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PDGFRB,PRKACB,FER,TNK2,MYLK3,MARK1,PDK1,ACVR1C,KCNH5,LRRK2,PRKCQ,ROR1,ACVR2B,FGF17,SGK2,FRK,GRK3,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAP3K21,MAPK13,HGF,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,EFEMP1,IGF1R,ADCK1,PRKCD,SGK3,PRKG1,PRKG2,SGK1,ALPK1,MAST4,SYK,FES,FGFR4,PAK1,CRIM1,EFNA3,NUAK2,STRADB,OBSCN,CDC42BPA,PEAK1,MAPKAPK2,FGR,PKN3,MAP2K6,AKT3,PELI2,NEK11,LRRK1,MAP3K20 |
| 2.803e-04 | -8.18 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | 108 | 23 | 17377 | 1707 |
MN1,GAPDH,GATA3,SELL,MAFB,HERC5,IL13RA1,SLC1A3,SATB1,FGFR1,CD53,ISG20,EPB41L3,TERT,DACT1,RPS11,BCL6,SH3BP4,RPS12,JAM2,PTPRE,CDH2,CEBPD |
| 2.810e-04 | -8.18 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_UP | 157 | 30 | 17377 | 1707 |
RHOQ,PTPRD,CAP2,STAT4,VLDLR,KIAA1324L,MSR1,GATA3,RNF125,FAM102B,TTC22,MFSD6,SNTB1,TEX9,SLCO3A1,CPEB1,SCIN,GNAI1,TLR3,CHN2,KIAA1257,MAOA,DSEL,RAB27B,KLHL29,RBMS2,SCN3A,RAB30,GAB2,RRAGD |
| 2.811e-04 | -8.18 | autonomic_ganglia | COSMIC cancer mutations | autonomic_ganglia | 4100 | 459 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,PPP4R4,ACVR1,TCP11L2,GRIK2,AASS,CNTNAP3,PRSS12,ATP8A1,DNAJC3,LDLR,PPFIBP2,TUBE1,FAM102B,NPM1,ADAMTS6,BCAN,DOCK3,KIAA1217,SNX9,NOS1AP,TRPS1,BAG3,FBXO32,TGFBR3,SLC22A18,PPFIA2,FAM168A,KCNS3,RCAN3,VWA5A,NKX2-1,GLDC,DCDC1,ACVR1C,TGFA,DSTN,NFIA,DEPTOR,ABCC2,FGF17,CA13,ARHGEF26,AHRR,ENPP1,NCKAP1L,CCBE1,BMP1,INPP5F,SERPINI1,UNC5B,DNHD1,C12orf77,SPOCK3,MEF2C,SEMA6B,SCN5A,LATS2,STOX2,INPPL1,CELSR1,PTPRD,ZHX3,TBC1D1,SCN8A,GABRB2,ITGA6,ZNF25,OPHN1,DYNC1I1,BBS9,MECOM,MCOLN2,SYCP2,FRY,KIAA1671,PDZD7,PIK3AP1,APLF,MYC,ZIC5,PRELID2,PRKG1,SREBF1,SRGAP1,CPXM2,TOX,CADPS2,FAM84B,DENND1C,NCAM1,GLIS1,PRR16,LRP12,RIMS2,GPR161,RPL26,QSOX1,SLC37A1,KCNQ3,TBC1D8B,MYO10,STAT4,DCHS1,EFHC2,FASN,PACSIN3,RYR2,TTC30A,SMARCD3,NPC2,CCDC85A,OR11H4,PLCB1,CACHD1,TEX15,TMCO3,PLEKHH2,SH3GL2,ISM1,CECR2,QPCTL,MPP2,SQLE,IQSEC2,SLFN5,TRPC3,CDH2,DOCK9,PLA2G4A,EPHA3,AMOTL1,RASAL2,ST14,ZNF311,LRRCC1,MSR1,PLXNA2,ADD2,PKP2,IL13RA1,COL14A1,ZFYVE9,TIAM2,CCDC120,EPB41L3,SPEG,DACT1,MAGEA3,NAP1L3,FAM155B,RAB27B,JAKMIP3,DNAH5,DOCK8,VNN2,SSH3,MYLK3,GARS,GAPDH,EBPL,TMEM43,SHANK2,PREX1,PRKCQ,ATF3,PYGO1,DSP,FGFR1,ZNF711,IKZF3,LAMB1,KLHL31,CTTNBP2,NR3C2,COBL,HACE1,MYO1D,PLSCR4,ANKRD13B,PLAG1,IPO5,PRSS35,ARL2,PSD3,GABRR2,CREB5,EPHB1,ZNF219,GDPD5,TSPAN17,COL27A1,NEO1,RGS17,LRRC55,MGAT1,AFF2,PCBP4,GAS2L3,SEPT3,GFI1,ZFP36L2,MED12L,B4GALT6,TRPM4,TMC7,PFKFB4,MN1,VAV3,ARAP2,CACNA1E,MCF2L2,RAPGEF2,PTPN13,ELOVL3,RASA3,GUCY1A2,SNTB1,HOXA1,ZIC1,PLOD2,TERT,OSBPL5,SLCO5A1,PGM2L1,SVIL,NEK11,GRIN2D,MYOM2,OCLN,LARP1,FOXA1,SLC43A1,TLL2,MPZL3,EXPH5,UGT8,TRIM16,PTPN21,FHDC1,LILRB1,SLC2A13,RBM11,SLCO3A1,HMCN1,RTN1,ARHGEF10L,SIPA1L2,EOMES,CPVL,ABI3BP,MARVELD2,TMEM86A,MPPED2,POF1B,JAKMIP2,TMEM132E,TLN2,MYRIP,NEB,SLIT2,RAPGEF5,RASGRP1,PDGFRB,TNK2,GPM6A,GCNT2,ABCC4,COL4A3,SPOCD1,YAP1,TMEM200C,CR2,CRYBG3,SERGEF,TMEM132B,GSN,HPSE,ITGBL1,MAP2,TECPR2,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,PPARGC1A,MLLT3,CHMP4C,PCSK5,LONRF1,PRKAA2,MOCOS,STXBP5L,FN1,SEC24D,SETBP1,RASL11B,LAMC3,GALNT13,SPINK5,FHOD3,PCDHB14,RNF180,GALNT1,ZBTB38,SLC30A4,ABCA5,FRAS1,SMTN,LRP6,NCEH1,FBXL2,MORN4,LRP3,NDUFA4L2,DPYSL5,RAX,PODXL2,PARD3B,GPSM1,TCEA3,SPATA13,PPFIA4,SDC3,OBSCN,DUSP9,STRADB,SDK1,PRDM1,B4GALNT3,MAPKAPK2,HEYL,FAT1,CSF1,RAI14,HK2,RAB31,PLD1,FNBP1L,XKR4,MME,CFH,DOCK1,CELSR3,PLEKHA5,LPCAT2,RHPN2,TDRKH,OR51B4,NTRK3,SEZ6L2,KIF21B,DENND3,TNKS1BP1,DOCK2,DDX60L,PCLO,ZSCAN5A,SCIN,FAM131B,TACC2,PPFIBP1,MYO3B,ZNF521,MAP7,WWC2,CLVS2,MET,ZNF460,HSPA2,NTNG1,CTH,GLI1,SUSD3,DPP10,PRAME,GCA,TMEM67,UROS,TDRD3,LRRC8B,PTPN6,TES,PRDM13,RNF125,VIM,AMIGO1,DOCK5,C1orf174,BCL11A,ZNF569,SMAD3,ARMC4,GBP1,ITGA2,SOHLH2,CTNND2,TNIK,PRSS16,BMPR2,ARHGEF11,CLGN,LRP4,MCTP2,COL4A5,IGF2BP2,CUEDC2,OVOL2,FOXP2,NKX6-1,KCNJ4,CHN2,FUT9,DSG2,KCNMB3,TSC22D1,KIAA0319,TRIM3,SGK1,TSPAN13,KIAA0408,IPCEF1,ESD,SLC45A3,TNFRSF11A,RBMS2,ATP2B1,CES3,RIN2,CARD6,LRRIQ1,CRIM1,CYTH3,LITAF,ASAP3,CCNG1,ARHGAP32,PALLD,TLR6,NAALADL2,LEPR,ILDR2,MAP1B,DKK1,ADAMTS17,MFSD9,FAT4,FBN1,MPP7,PRCP,MAP2K6,ZNF808,SLC22A15,KIF21A,RNF157,NPHP1,FILIP1 |
| 2.824e-04 | -8.17 | regulation of kinase activity | biological process | GO:0043549 | 892 | 117 | 17256 | 1658 |
EPHA3,PRKN,NEK10,ACSL1,AVPI1,FGF13,DUSP8,DNAJC3,NPM1,CEBPA,NTRK3,LCP2,SNX9,PIBF1,DDR1,PPP1R9A,STK24,PPM1E,TLR3,ZFYVE28,ITGB3,DAB2IP,EPHB6,MET,TLR4,PRKACB,RASGRP1,PDGFRB,SESN2,FZD4,PFKFB2,PTPN6,TGFA,LRRK2,PREX1,ADCY1,DEPTOR,PRKAR2B,WNT11,ACVR2B,ROR1,CD40,FGFR1,SNCA,WARS,CAMK2N1,IRS2,CXCL10,NRG3,PTPRJ,GPRC5B,NCKAP1L,ERN1,WWTR1,MAP3K21,DUSP19,TNFSF15,HGF,DIRAS1,SPRY4,MAPK10,CACUL1,TENM1,TYRO3,LATS2,TNIK,PAK5,SLK,FZD8,UBASH3B,IPO5,HERC5,GAS6,PKN1,EPHB1,TPD52L1,IGF1R,FLRT3,PRKCD,GHR,LRP6,ADCY6,INAVA,AFAP1L2,IQGAP3,ERRFI1,TNFRSF11A,SYK,SPRY2,HMGCR,DUSP1,PAK1,FGFR4,VAV3,MSTN,RAPGEF2,VLDLR,STRADB,DUSP9,AGAP2,CCNG1,RACK1,TLR6,DKK1,MAPKAPK2,PTPRC,TRIB3,FGR,CSF1,MAP2K6,BMP4,SMYD3,MAP3K20,TESC,ATP2B4,SFN,PKIA |
| 2.833e-04 | -8.17 | GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 29 | 10 | 17377 | 1707 |
GSTM2,CACNB2,ANK2,RYR2,GSTO1,BMP4,ATP1B1,ASPH,HSPA2,CACNA2D1 |
| 2.833e-04 | -8.17 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 29 | 10 | 17377 | 1707 |
CEBPB,TRIB3,ATF4,PMAIP1,XBP1,ERN1,BBC3,DAB2IP,CHAC1,DDIT3 |
| 2.858e-04 | -8.16 | Tyr_kinase_AS | interpro domains | IPR008266 | 95 | 21 | 18492 | 1811 |
EPHA3,FGFR4,TYRO3,FER,TNK2,NEK10,OBSCN,NTRK3,ROR1,EPHB1,PEAK1,DDR1,FRK,FGFR1,FGR,IGF1R,PTK7,MET,SYK,FES,PDGFRB |
| 2.887e-04 | -8.15 | positive regulation of metabolic process | biological process | GO:0009893 | 3331 | 374 | 17256 | 1658 |
THOC5,ACVR1,LGR4,DNAJC3,LDLR,GATA3,NPM1,CTBP2,STAT5B,CEBPA,PRKCA,SNX9,ABHD6,EYA4,STK24,NOS1AP,TRPS1,SKI,PMAIP1,FAM168A,RAP2A,TSHR,POU3F3,NKX2-1,MEIS2,SMAD9,ACVR1C,NR6A1,TGFA,LRRK2,NFIA,BNIP3L,MEF2B,PRKAR2B,ACVR2B,F12,AHRR,HLF,NCKAP1L,CCBE1,PLK2,ADRB1,BBC3,DIRAS1,INPP5F,NRP1,MEF2C,ITGA6,SLK,TNFRSF10C,TNFRSF19,MECOM,APLF,MYC,PRELID1,SREBF1,GRIP1,GLIS1,PRR16,RIMS2,GPR161,RNF152,HMGCR,RPL26,STAT4,VLDLR,FHL2,FASN,PACSIN3,NSD2,HIP1,SMARCD3,TAF4B,ARRDC4,PLCB1,FAM162A,PELI2,THBS4,INHBE,HOXD13,CDH2,SMYD3,EPHA3,ZNF516,RNF144A,OTX1,CHUK,LCP2,DDR1,TLR3,DACT1,STARD4,DAB2IP,PERP,FZD1,ADM2,FZD4,PFKFB2,SOX21,ADCY1,ATF3,SATB2,PRKCQ,WNT11,PXYLP1,PYGO1,ATOH1,ASPH,FGFR1,SNCA,IRS2,ZNF711,CXCL10,IKZF3,BEX3,WFS1,APELA,PEMT,WWTR1,MAP3K21,TNFSF15,KLF5,BMPR1A,DBP,MAPK10,HOXB9,MID1,EDA2R,CKAP2,PLAG1,CD276,FZD8,GAS6,P2RY1,CREB5,PKN1,EPHB1,ZNF219,NDFIP2,TPD52L1,NEDD4,GSAP,KDM7A,BHLHA15,GHR,YBX3,MYO6,SMAD6,SPRY2,ZFP36L2,MED12L,PARP9,PFKFB4,VEGFC,SLC40A1,VAV3,RAPGEF2,GAREM1,RACK1,GUCY1A2,SKAP1,HOXA1,ZIC1,GPLD1,CEBPB,PTPRC,TRIB3,NSD1,FGR,TERT,XBP1,BMP4,LRRK1,SHOX2,DDIT3,ATP2B4,FOXA1,LARP1,BTRC,ACSL1,FGF13,TRIM16,JCHAIN,LILRB1,ASS1,ABAT,IKZF2,F3,GSDME,ARHGEF10L,EPCAM,EOMES,SEC16B,GRHL1,ITGB3,PCOLCE2,EPHB6,ENO1,FANK1,TLR4,ETV1,PDGFRB,RASGRP1,PRKACB,LAMP3,TNK2,ATF4,GCNT2,SESN2,COL4A3,ANK2,NFE2L1,YAP1,ROR1,BATF,SESN1,DYRK1B,INHBC,GSN,GPRC5B,INSIG1,ERN1,NCOA7,TNFRSF1A,DLX2,PPARGC1A,TNFSF4,MAGI2,CACUL1,MLLT3,BCL11B,PRKAA2,TYRO3,LONRF1,RUNX2,FN1,BVES,FBXO4,JDP2,SORBS3,ZIC2,PFN2,RNF180,ZBTB38,EEF2,IGF1R,GATA2,EBF4,LRP6,ADCY6,INAVA,BNIP3,BARX1,CAND2,CEBPD,NOS3,PAK1,FGFR4,RAX,ATP5IF1,MID2,RHOQ,MSTN,GPSM1,EFNA3,WWC1,MAFB,STRADB,DUSP9,PDE8A,PRDM1,HERPUD1,MAPKAPK2,PLAGL1,CSF1,HEYL,SH3BP4,HK2,NKX2-8,SEMA3A,TESC,SIX2,CREB3L2,PRKN,SORBS1,ID1,NEK10,AVPI1,IL15,HECW2,NTRK3,LPIN3,TNKS1BP1,PIBF1,PPP1R9A,CDC14B,BCL6,ACVR2A,POU2F2,MET,HSPA2,GLI1,IGFBP3,ALG10B,NOP53,RNF125,VIM,RARRES2,CD40,C4BPB,WARS,CAMK2N1,SMAD3,NRG3,RNF217,ITGA2,DUSP19,SOHLH2,HGF,HEY1,CNTN1,TENM1,TNIK,NECAB2,BMPR2,ARHGEF11,PAK5,REL,APBB1,LRP4,SLX1B,OVOL2,BMP6,NKX6-1,PRKCD,RASD2,GTF2F2,TFAP2A,ACTA2,AFAP1L2,SH3PXD2B,IQGAP3,TNFRSF11A,SYK,SLC45A3,MOB1B,MICAL2,MSX1,KDM5B,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,PRICKLE1,MARS,AGAP2,ZFPM2,TLR6,MGMT,DKK1,RERE,EBF1,GPR37,DDAH1,DOCK7,EDA,ACER2,MAP2K6,MYRF,PAX9,MAP3K20,KIF1B,ABCG1 |
| 2.890e-04 | -8.15 | regulation of JNK cascade | biological process | GO:0046328 | 168 | 31 | 17256 | 1658 |
PAK1,PRKN,TNIK,EDA2R,GRIK2,FZD4,FZD8,PKN1,EPHB1,PLCB1,TPD52L1,TLR6,TNFRSF19,MAGI3,MECOM,DKK1,TGFBR3,TLR3,IGF1R,SH3RF1,DACT1,RAP2A,ERN1,MAP3K21,DUSP19,DAB2IP,SEMA3A,TNFRSF11A,SYK,MAP3K20,RASGRP1 |
| 2.899e-04 | -8.15 | GO_INTERCALATED_DISC | MSigDB lists | GO_INTERCALATED_DISC | 51 | 14 | 17377 | 1707 |
PAK1,SCN5A,FGF13,SCN1B,TMEM65,ANK2,DSG2,PKP2,TJP1,ATP1B1,SCN2A,DSP,CDH2,GJC1 |
| 2.920e-04 | -8.14 | V$RSRFC4_01 | MSigDB lists | V$RSRFC4_01 | 224 | 39 | 17377 | 1707 |
TYRO3,ARHGAP26,NDRG2,SLCO3A1,NEDD4,PPP2R3A,TRPS1,ZNF362,TSC22D1,BNIP3,TSPAN13,HRASLS,SSH3,PPP1R3D,ARAP2,USP2,RNF145,NR4A1,MGST3,PANK1,TCEA3,FGF12,STRADB,TTYH2,ATF3,ARHGAP32,PRDM1,ZFPM2,MBNL2,KPNA3,PMEPA1,DIRAS1,DLG2,TNFRSF17,CTNND2,FILIP1,AMPD1,MEF2C,CNTN1 |
| 2.924e-04 | -8.14 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_DN | 122 | 25 | 17377 | 1707 |
BDNF,SIDT1,FZD4,DCC,KCNH5,MPP1,NKAIN2,PDE8A,LHPP,CD40,TBC1D16,IL18R1,TSPAN17,PCDH7,TBC1D2,RERE,DKK1,MCOLN2,BAG3,CPNE2,SUGT1,BCHE,KCNG1,LRP12,HRASLS |
| 2.932e-04 | -8.13 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_UP | 194 | 35 | 17377 | 1707 |
FN1,KCTD12,TJP1,FAM198B,SLC1A3,ABI3BP,ACTA2,MARCKS,SERPINH1,TLR4,CYP1B1,SLC40A1,ANK2,WLS,ATOX1,FERMT2,YAP1,TNS1,C1R,CTTNBP2NL,RARRES2,GJC1,CXCL10,GPRC5B,FCHO2,FBN1,TDO2,RND3,LAMB1,WWTR1,RAI14,PLD1,TPM1,LIFR,CSRP2 |
| 2.943e-04 | -8.13 | GO_LEADING_EDGE_MEMBRANE | MSigDB lists | GO_LEADING_EDGE_MEMBRANE | 129 | 26 | 17377 | 1707 |
EPB41L5,PAK1,MYO1D,ATF4,ROBO2,AKAP5,WLS,EPS8,SPATA13,WWC1,GABRG2,FERMT2,PLEKHA1,ARHGAP44,GABARAPL1,EPB41L3,FGR,PTPRJ,ITGB3,SPRY4,PACSIN1,TPM1,MYO6,SPRY2,TESC,ATP2B1 |
| 2.943e-04 | -8.13 | V$PR_02 | MSigDB lists | V$PR_02 | 129 | 26 | 17377 | 1707 |
CCDC126,BDNF,PXN,ZNF395,KCNH5,ITGA6,DSTN,JPH1,OTX1,CALCRL,FGF17,IKZF2,NEDD4,FSTL5,RERE,MAP1B,ID3,NSD1,OPN3,BCL6,ADCY6,DLX2,FIGN,SEMA3A,FES,RAB30 |
| 2.945e-04 | -8.13 | muscle organ development | biological process | GO:0007517 | 292 | 47 | 17256 | 1658 |
BVES,ASS1,PKP2,DNER,MYORG,SKI,FOXP2,SPEG,TGFBR3,EOMES,EEF2,KCNAB1,SMTN,COL19A1,MYH15,ETV1,NEB,FZD1,MSX1,USP2,MSTN,JPH1,ARID5B,MEF2B,RYR2,ATF3,ZFPM2,DSP,HEG1,MKX,ID3,CXCL10,MSC,HLF,RIPOR2,POPDC3,HEYL,XBP1,SVIL,KLF5,MYOM2,BMP4,DISP1,BMPR1A,TPM1,SHOX2,MEF2C |
| 2.968e-04 | -8.12 | ovary-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | ovary-carcinoma-endometrioid_carcinoma | 466 | 69 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PDGFRB,PRKACB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,FBXO4,EPHB1,PKN1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,MAPKAPK2,TRIB3,FGR,PKN3,TERT,AKT3,MAP2K6,NEK11 |
| 2.969e-04 | -8.12 | GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_DN | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_DN | 172 | 32 | 17377 | 1707 |
BTC,ST6GAL1,ELOVL7,LRRCC1,PKP2,CBS,GPR180,NDFIP2,ABHD6,ZSCAN5A,GRHL1,REEP1,GAN,PCOLCE2,CTH,LAMP3,GPM6A,WLS,TMTC4,PRRG1,ST6GALNAC3,PRKAR2B,EXOG,SESN1,ASPH,TBC1D16,ENPP1,TRIB3,PLOD2,PAM,SERPINI1,LPP |
| 2.984e-04 | -8.12 | transmembrane transporter complex | cellular component | GO:1902495 | 321 | 50 | 18223 | 1724 |
KCNV1,SCN5A,CACNG3,GRIK2,GABRB2,SCN8A,GABRG2,GABRR2,KCNC4,CACNB4,ABHD6,NOS1AP,MCU,LRRC55,KCNJ4,KCNAB1,CHRNA5,SCN1B,CACNB2,KCNMB3,KCNS3,CTTN,PDE4D,SCN2A,HSPA2,SCN3A,KCNB2,DPP10,TRPM4,KCNIP3,KCNQ3,LRRC8B,CACNA1E,SHANK2,TTYH2,RYR2,CHRNA6,CATSPERE,AMIGO1,KCND3,SNAP25,ATP1B1,HERPUD1,GRIK4,KCNMB4,KCNG1,DLG2,GRIN2D,CACNA2D1,ATP1A3 |
| 2.991e-04 | -8.11 | GO_ENZYME_ACTIVATOR_ACTIVITY | MSigDB lists | GO_ENZYME_ACTIVATOR_ACTIVITY | 447 | 67 | 17377 | 1707 |
ARHGAP26,RASAL2,FGF13,DOCK1,ARHGAP22,RGS20,FAM13A,DOCK2,TBC1D30,TIAM2,TBC1D19,ADPRHL1,SIPA1L2,DAB2IP,PCOLCE2,IGFBP3,TBC1D8,LRRK2,PREX1,ELMOD1,WNT11,ATP1B1,TBC1D16,ARHGAP21,NRG3,GPRC5B,NCKAP1L,RGS10,DUSP19,ARHGAP28,RGS16,FN1,STXBP5L,ALOX5AP,TBC1D1,ARHGEF11,OPHN1,GAS6,RGS7,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,PRKCD,SRGAP1,RALGAPA2,AFAP1L2,IQGAP3,TBC1D9,ERRFI1,SPRY2,MOB1B,RIN2,VAV3,ARAP2,TBC1D8B,RAPGEF2,ASAP3,RASA3,AGAP2,ARHGAP32,PLCB1,TBC1D2,MMP15,TBC1D4,MMP16 |
| 2.991e-04 | -8.11 | signal transducer, downstream of receptor, with serine/threonine kinase activity | molecular function | GO:0004702 | 123 | 25 | 17224 | 1680 |
EPHA3,FGFR4,TYRO3,TNIK,ACVR1,BMPR2,ACVR1C,MAPK4,NTRK3,ROR1,ACVR2B,EPHB1,DDR1,STK24,FGFR1,IGF1R,MAP3K21,ACVR2A,MAPK13,EPHB6,BMPR1A,MET,MAPK10,MAP3K20,PDGFRB |
| 3.004e-04 | -8.11 | Signaling pathways regulating pluripotency of stem cells | KEGG pathways | hsa04550 | 139 | 28 | 7161 | 730 |
FGFR4,ACVR1,ID1,SMAD9,BMPR2,FZD4,ACVR1C,FZD8,OTX1,DUSP9,WNT11,ACVR2B,FGFR1,SMAD3,INHBC,ID3,IGF1R,POU5F1B,MYC,AKT3,PCGF2,INHBE,ACVR2A,MAPK13,BMP4,BMPR1A,LIFR,FZD1 |
| 3.004e-04 | -8.11 | Signaling pathways regulating pluripotency of stem cells | KEGG pathways | ko04550 | 139 | 28 | 7161 | 730 |
FGFR4,ACVR1,ID1,SMAD9,BMPR2,FZD4,ACVR1C,FZD8,OTX1,DUSP9,WNT11,ACVR2B,FGFR1,SMAD3,INHBC,ID3,IGF1R,POU5F1B,MYC,AKT3,PCGF2,INHBE,ACVR2A,MAPK13,BMP4,BMPR1A,LIFR,FZD1 |
| 3.007e-04 | -8.11 | molecular function regulator | molecular function | GO:0098772 | 1837 | 222 | 17224 | 1680 |
ARHGAP26,PHACTR3,CACNG3,PPP4R4,FGF13,RECK,DNAJC3,VAMP8,HDGFL3,NPM1,DOCK3,FAM13A,SKI,ARHGEF10L,ADPRHL1,BAG3,SIPA1L2,TYMP,PPP1R26,KCNAB1,HPS1,KCNS3,PPP2R2B,PCOLCE2,RCAN3,RAPGEF5,SLIT2,RASGRP1,PDGFRB,TBC1D8,TNK2,KCNIP3,SESN2,COL4A3,WISP3,TGFA,LRRK2,ELMOD1,PRKAR2B,FGF17,SGK2,SERGEF,ARHGEF26,INHBC,KCNMB4,GPRC5B,NCKAP1L,RASGRF2,ADRB1,BMP1,ARHGAP28,SEMA3C,SERPINI1,NRP1,TNFSF4,SPOCK3,KCNV1,RGS16,ALOX5AP,FN1,STXBP5L,LGALS3,TBC1D1,OPHN1,GPSM2,SPINK5,HPCAL4,GRPEL2,EFEMP1,IL17D,CHN1,RALGPS2,FRY,SEMA4F,FLRT3,SRGAP1,PRKG1,LRP6,NCAM1,DENND1C,GFRA1,BOD1,FGFR4,BDNF,ATP5IF1,MSTN,TBC1D8B,RAPGEF4,GPSM1,SPATA13,PACSIN3,OBSCN,PLCB1,TBC1D2,MMP15,ADGRB3,THBS4,CSF1,SH3BP4,INHBE,IQSEC2,SEMA3A,TESC,SFN,DOCK9,NBL1,BTC,PCSK1N,RASAL2,DOCK1,IL15,C4A,ARHGAP22,RGS20,PKP2,NRXN1,COLEC10,DENND3,TBC1D30,DOCK2,TIAM2,TBC1D19,CNKSR3,DAB2IP,PROS1,SERPINH1,MET,DOCK8,IGFBP3,DPP10,GAPDH,CSN2,ADM2,PREX1,FGF12,WNT11,ATP1B1,AMIGO1,TBC1D16,DOCK5,FGFR1,SNCA,WARS,CAMK2N1,IRS2,RANBP2,ARHGAP21,CXCL10,NRG3,BEX3,APELA,PLEKHG1,RGS10,DUSP19,TNFSF15,HGF,DENND5B,ARFGEF3,CGB2,FARP1,IL32,ARHGEF11,EPS8,IPO5,CMTM8,TNFSF13B,ARL2,PSD3,GAS6,RGS7,BMP6,NEDD4,PPP2R3A,ARHGAP44,SYDE2,RGS17,LRRC55,CHN2,SCN1B,MCF2L,PRKCD,STC2,KCNMB3,SGK3,SGK1,RALGAPA2,AFAP1L2,TSPAN13,IPCEF1,SH3PXD2B,ERRFI1,TBC1D9,SPRY2,PARP9,MOB1B,VEGFC,VAV3,RIN2,ARAP2,ARHGEF28,CRIM1,RAPGEF2,MCF2L2,CYTH3,ASAP3,RASA3,AGAP2,PHACTR2,ARHGAP32,RACK1,DKK1,GPLD1,TRIB3,DOCK7,FBN1,GRIN2D,BMP4,TBC1D4,DOCK6,MMP16,ATP2B4,PKIA |
| 3.017e-04 | -8.11 | Ibandronate Action Pathway | SMPDB pathways | SMP00079 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Mevalonic aciduria | SMPDB pathways | SMP00510 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Wolman disease | SMPDB pathways | SMP00511 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Hypercholesterolemia | SMPDB pathways | SMP00209 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Steroid Biosynthesis | SMPDB pathways | SMP00023 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Smith-Lemli-Opitz Syndrome (SLOS) | SMPDB pathways | SMP00389 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Pamidronate Action Pathway | SMPDB pathways | SMP00117 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Atorvastatin Action Pathway | SMPDB pathways | SMP00131 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | CHILD Syndrome | SMPDB pathways | SMP00387 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Zoledronate Action Pathway | SMPDB pathways | SMP00107 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Cholesteryl ester storage disease | SMPDB pathways | SMP00508 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Lysosomal Acid Lipase Deficiency (Wolman Disease) | SMPDB pathways | SMP00319 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Lovastatin Action Pathway | SMPDB pathways | SMP00099 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Risedronate Action Pathway | SMPDB pathways | SMP00112 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Simvastatin Action Pathway | SMPDB pathways | SMP00082 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Fluvastatin Action Pathway | SMPDB pathways | SMP00119 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Rosuvastatin Action Pathway | SMPDB pathways | SMP00092 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Desmosterolosis | SMPDB pathways | SMP00386 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Pravastatin Action Pathway | SMPDB pathways | SMP00089 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Alendronate Action Pathway | SMPDB pathways | SMP00095 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Chondrodysplasia Punctata II- X Linked Dominant (CDPX2) | SMPDB pathways | SMP00388 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Cerivastatin Action Pathway | SMPDB pathways | SMP00111 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.017e-04 | -8.11 | Hyper-IgD syndrome | SMPDB pathways | SMP00509 | 21 | 9 | 992 | 118 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR |
| 3.029e-04 | -8.10 | V$OCT1_05 | MSigDB lists | V$OCT1_05 | 232 | 40 | 17377 | 1707 |
LRFN5,RHOBTB1,CADM2,IKZF2,PPP2R3A,FSTL5,SLC9A7,MTUS1,FOXP2,PPM1E,GALNT1,LRRN1,SLC7A11,COL25A1,LHX6,SLC6A15,TSPAN13,PDE4D,SEMA6C,NKX2-1,GPM6A,ARAP2,FZD4,ESRRG,STAT4,SATB2,DKK1,EBF1,TCF7L1,ENPP1,GPRC5B,PRKCB,MAP2K6,SVIL,TMOD2,ZBTB20,HOXB9,MID1,TLL2,LPP |
| 3.035e-04 | -8.10 | GO_UROGENITAL_SYSTEM_DEVELOPMENT | MSigDB lists | GO_UROGENITAL_SYSTEM_DEVELOPMENT | 294 | 48 | 17377 | 1707 |
EFNB2,ROBO2,LGR4,PLAG1,ITGA6,LRP4,GATA3,ASS1,BMP6,EPCAM,CA2,ZNF354A,GATA2,FRAS1,MYC,TFAP2A,ACTA2,SMAD6,SLIT2,POU3F3,PDGFRB,SMAD9,COL4A3,KLHL3,COL4A4,DCHS1,LRRK2,ARID5B,WNT11,ACVR2B,PYGO1,FGFR1,SMAD3,ID3,FAT4,FBN1,WFS1,HEYL,WWTR1,HOXD13,BMP4,NRP1,MAGI2,FOXA1,MME,SIX2,PCSK5,MEF2C |
| 3.036e-04 | -8.10 | response to stimulus | biological process | GO:0050896 | 8006 | 836 | 17256 | 1658 |
ARHGAP26,PDE1B,GRIK2,DNAJC3,NPM1,STAT5B,CEBPA,CHAC1,DOCK3,CA8,EYA4,SKI,TXNDC5,BAG3,FBXO32,TGFBR3,PMAIP1,RAP2A,RAB26,TSHR,CPE,NKX2-1,MEIS2,SMAD9,DCC,WLS,CAP2,TGFA,LRRK2,MSRB3,FEZ1,PRKAR2B,ABCC2,FGF17,F12,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,ALDOA,ADRB1,ARHGAP28,BBC3,ERCC5,DIRAS1,INPP5F,TPM1,TMEFF2,MEF2C,SCN5A,GNG12,LATS2,CYP2J2,ITGA6,SLK,TJP1,SLC36A4,GPSM2,BBS9,FOXG1,HPCAL4,CHN1,APLF,FLRT3,SRGAP1,CADPS2,ST8SIA1,NCAM1,AGL,STXBP1,TSPAN9,GFRA1,LRP12,CHRM3,ZNF385A,HMGCR,FADS1,BDNF,PNP,MYO10,STAT4,MGST3,ARID5B,EFHC2,FHL2,FASN,RYR2,HIP1,CALCRL,C1R,SNAP25,OR11H4,ARRDC4,SPATA7,CPEB1,TEX15,GSTO2,SH3GL2,CDH17,INHBE,SELENOM,HOXD13,TRPC3,SHTN1,DOCK9,BTC,ZNF516,SCAMP1,C4A,IL13RA1,MAPK4,GRK6,COLEC10,NRXN1,LCP2,SLC19A2,TXNRD3,CDS1,GPR15,PLPP1,TLR3,CHRNA5,KMO,CNKSR3,DACT1,RTKN2,RAB27B,SNX10,PERP,DOCK8,FZD1,MYLK3,GAPDH,COL6A2,ADM2,FZD4,PFKFB2,KCNH5,ADCY1,WNT11,RAB38,DSP,FGFR1,MAGI3,GABARAPL1,IRS2,ENTPD1,CXCL10,ARHGAP21,WFS1,GPR160,PEMT,APELA,WWTR1,INPP4B,PAM,TNFSF15,LRRC27,HOXB9,RAB30,CGB2,SERINC5,EDA2R,ROBO2,FZD8,ESRP1,CD276,IPO5,CBS,GAS6,P2RY1,SLC12A6,PKN1,EPHB1,ZNF219,TSPAN17,NEO1,HMGCS1,PCBP4,MCF2L,BHLHA15,GHR,MYO6,ZFP36L2,FES,PARP9,ULBP1,PDLIM7,TRPM4,B9D1,VEGFC,RAB6B,RAPGEF2,RASA3,AK4,GAREM1,ATP11A,RACK1,GALNT3,PTPRC,TRIB3,ID3,PLOD2,PLPPR2,AKT3,GNAO1,XBP1,NEK11,BMP4,CMPK2,DOCK6,ATP2B4,FOXA1,BTRC,TPT1,NMNAT3,FGF13,TRIM16,LILRB1,ASS1,NDRG2,ITPR2,FAM13A,RND2,CPNE2,RPS6KA2,EOMES,HPS1,ITGB3,TBC1D32,ETV1,TLR4,ENO1,RAPGEF5,ITGB7,CD55,KCNIP3,SLC3A2,GCNT2,MARK1,ATF4,COL4A3,ANK2,ATOX1,PLPP2,NFE2L1,CR2,PLEKHA1,BATF,SESN1,PLEKHB1,TSKU,SPNS1,INHBC,TCF7L1,KCNMB4,INSIG1,MAP2,GNB4,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,ADGRA3,ADGRL2,CACUL1,RRAGD,PRKAA2,TYRO3,RGS16,RUNX2,LGALS3,HID1,UBASH3B,RASL11B,MLC1,IL18R1,DOK5,EFEMP1,NUMBL,ZBTB38,SEMA4F,IGF1R,BCHE,GATA2,PDE10A,LRP6,ADCY6,BNIP3,SLCO4C1,PTPRCAP,CKAP4,PAK1,FGFR4,DPYSL5,UNC5C,MID2,BTNL9,SLC27A2,HOMER2,EFNA3,SLITRK5,STRADB,OBSCN,PDE8A,SDK1,GPR19,BAIAP2,MAPKAPK2,GRIK4,HEYL,CSF1,PLD1,SEMA3A,TESC,MME,SFN,PRKN,ID1,CFH,AKAP5,DOCK1,RBFOX2,RHPN2,OR51B4,NTRK3,SLC7A2,PRR7,TNKS1BP1,RADIL,PCLO,PPP1R9A,SEMA6A,CTNNA2,CYP26A1,RIDA,SLC22A17,MYO3B,BCL6,EEPD1,ADGRL1,SCN2A,SNAI2,GLI1,CTH,EVL,TMEM67,UROS,LRRC8B,NOP53,FGF12,ACO1,RNF125,CHRNA6,VIM,GSTO1,RARRES2,FRK,JAM3,C4BPB,SMAD3,NRG3,PTPRJ,GBP1,PTK7,ITGA2,MAOA,HGF,SUSD4,CTNND2,CNTN1,HEY1,TENM1,LPAR2,SLC6A9,IL32,BMPR2,GRB14,PAK5,APBB1,NLRP14,MCTP2,GABRG2,SELL,HBE1,RASD1,ARHGAP44,FOXP2,RASD2,KCNMB3,GTF2F2,TFAP2A,SGK1,PRICKLE2,TSPAN13,KLF9,PCK2,ESD,SYK,ATP2B1,CES3,DUSP1,MOB1B,NUGGC,FOXN3,LITAF,NUAK2,FERMT2,PRICKLE1,ILDR2,MGMT,SMPDL3B,HOMER3,DKK1,DDAH1,CD37,DOCK7,FAT4,FBN1,DLG2,PAX9,SLC1A5,TBC1D4,PTGES,KIF1B,CACNA2D1,CGN,PAGE1,ACVR1,LANCL3,LGR4,ATP8A1,LDLR,VAMP8,GATA3,ENAH,PRKCA,RAC3,AARS,NCS1,STK24,MOK,TYMP,SLC22A18,CFHR1,CHRDL1,GSTM3,ATRNL1,SP140,RCAN3,GLDC,GDAP1,DCDC1,ACVR1C,WISP3,NR6A1,LRMP,BNIP3L,DEPTOR,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,GNAI1,GPR150,AHRR,NCKAP1L,RASGRF2,PLK2,MAPK13,SEMA3C,UNC5B,NRP1,SPOCK3,EFNB2,MRC2,INPPL1,ALOX5AP,CELSR1,PTPRD,GABRB2,ST6GAL1,DHCR24,OPHN1,SLC25A27,SLC1A3,TNFRSF10C,TNFRSF19,ADSSL1,GAS1,RPL13A,MCOLN2,IL17D,RALGPS2,SLC7A11,CNTN4,PIK3AP1,PDZD7,MYC,PRELID1,SREBF1,PRKG1,OPN3,GRIP1,TSPAN12,MAST4,GPR161,RIMS2,IGSF3,RNF152,EPB41L5,PTCH2,RPL26,QSOX1,DISC1,SLC36A1,VLDLR,DCHS1,RAPGEF4,NSD2,NPC2,CDC42BPA,PLCB1,FAM162A,MMP15,DAGLA,PMEPA1,PKN3,PELI2,THBS4,WDR19,MATN2,MPP2,SQLE,SMYD3,AMPD1,PLA2G4A,FRMPD3,EPHA3,TBKBP1,AMOTL1,PCSK1N,TCTN2,RASAL2,ELOVL4,RHOD,GPR65,PLXNA2,CHUK,DDR1,TIAM2,ZFYVE9,ASNS,ALDOC,SHF,DAB2IP,PDE4D,SERPINH1,GATM,GAB2,TRDMT1,PDK1,PREX1,PRKCQ,SATB2,ATF3,ATP1B1,ATOH1,PYGO1,ISG20,SNCA,DCBLD2,PATJ,HTR7,PRKCB,BEX3,ASIC1,MAP3K21,HPGD,KLF5,GRB10,BMPR1A,ATG5,MAPK10,NR3C2,MID1,DENND5B,HACE1,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,GPR180,GABRR2,NDFIP2,RGS7,SELENOP,INPP1,NEDD4,ADGRB2,RASSF8,IRX5,GPR155,SGK3,PRKG2,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,SLC40A1,VAV3,SH3BP2,PXN,ARAP2,GSTM2,ARHGEF28,PTPN13,MPP1,GUCY1A2,SKAP1,HOXA1,GPLD1,CEBPB,FGR,OR2T33,TERT,PCGF2,MCC,TUFT1,GRIN2D,LRRK1,TNFRSF17,CERS1,DDIT3,OCLN,LARP1,ATP1A3,ACSL1,KIF5A,HEBP1,TNFAIP8L2,JCHAIN,ABAT,RBM11,DNER,KREMEN1,HMCN1,F3,GSDME,EPCAM,ARHGEF10L,PPM1E,TRPC1,PCOLCE2,EPHB6,OR2W3,SLIT2,IL1RAP,PRKACB,RASGRP1,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,CAPN5,YAP1,ROR1,COTL1,SGK2,SERGEF,GRK3,GSN,GPRC5B,HPSE,OXTR,PPARGC1A,TNFSF4,MAGI2,BCL11B,GPR63,FN1,RHOBTB1,BVES,SCART1,FBXO4,CYP4V2,ATP6V1E2,CHSY1,CD7,SATB1,PHGDH,ADGRG6,DDIT4,EEF2,SLC30A4,CA2,ZNF354A,INAVA,NCEH1,MORN4,CEBPD,NOS3,GPR176,IL17RD,ATP5IF1,HBG2,RHOQ,MSTN,SH2D2A,GSTM4,EDEM3,WWC1,DUSP9,PRDM1,HERPUD1,RIPOR2,ADGRB3,PLAGL1,SH3BP4,RAB31,HK2,PTPRN2,NXPH4,TMEM117,DISP2,CREB3L2,CXCR5,SORBS1,CELSR3,IL15,ARHGAP22,COL18A1,BCL6B,CANX,DOCK2,CD53,UNC13B,PDZD8,CDC14B,RPS6KL1,MAP7,ACVR2A,FHIT,PROS1,GULP1,POU2F2,MET,HSPA2,SEMA6C,GCA,FER,ANTXR2,PTPRU,PTPN6,SYNJ2BP,CD40,DOCK5,BATF3,BCL11A,MSC,TRIM34,EIF4EBP1,RGS10,FAAP20,DISP1,CYP2U1,LIFR,PSPH,MAST1,OR51B5,TNIK,TSPAN15,ARHGEF11,REL,LRP4,CMTM8,TNFSF13B,COL4A5,SLX1B,NOTUM,BMP6,MCU,SYDE2,NKX6-1,RAB11FIP5,CHN2,SCN1B,PRKCD,EHD3,STC2,DSG2,ACTA2,AFAP1L2,IPCEF1,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,USP2,RAB3B,MSX1,KDM5B,HNF4G,CRIM1,ESRRG,NR4A1,GRID1,MARS,ARHGAP32,ZFPM2,TLR6,LRAT,LEPR,GPR37,TIFA,EDA,RND3,ACER2,PRCP,MAP2K6,CTSV,UACA,GEM,IL9R,MAP3K20,NPHP1,ABCG1,STOM |
| 3.038e-04 | -8.10 | negative regulation of cytoskeleton organization | biological process | GO:0051494 | 132 | 26 | 17256 | 1658 |
PRKN,PHLDB2,TMEM67,FGF13,TMSB15A,CKAP2,EPS8,NPM1,ADD2,HDGFL3,PFN2,PPP1R9A,FHOD3,SNCA,SCIN,TUBB4A,GSN,PLEKHH2,MYADM,PRKCD,ARHGAP28,TMOD2,MET,TMEFF2,MID1,SLIT2 |
| 3.061e-04 | -8.09 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP | 187 | 34 | 17377 | 1707 |
BCL11B,TNIK,PRSS16,TBC1D1,GALNT6,ELOVL7,SLC25A27,STAT5B,SATB1,BBS9,KREMEN1,SKI,CA2,RALGPS2,FRY,ZFYVE28,FAM168A,EIF1,BCL6,ADCY6,FAM84B,EPHB6,TMEM120B,LRP12,ARAP2,MYO10,RAPGEF4,ZDHHC15,RASA3,BACH2,PRKCB,INPP5F,ERCC5,FNBP1L |
| 3.061e-04 | -8.09 | GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY40_DN | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY40_DN | 187 | 34 | 17377 | 1707 |
CREB3L2,FLVCR2,IGFBP6,SEC24D,APBB1,GATA3,C20orf194,RBM11,TNKS1BP1,PIBF1,SEMA6A,NCS1,ARHGAP44,EPDR1,TBC1D19,PCBP4,LIN7A,CERS4,HSPA2,SLIT2,FKBP14,DUSP1,CHSY3,FER,FHL2,EFHC1,TDO2,PMEPA1,CSF1,OSBPL5,LAPTM4B,SERPINI1,SEMA3C,BMPR1A |
| 3.061e-04 | -8.09 | EGFR_UP.V1_DN | MSigDB lists | EGFR_UP.V1_DN | 187 | 34 | 17377 | 1707 |
EFNB2,DMXL2,MOCOS,COL9A3,ID1,HEBP1,EPS8,KIF5C,OVOL2,HERC6,PRR7,CHN1,SYCP2,ABLIM1,IGF1R,SGK3,MPDZ,GULP1,CPE,AGL,GFRA1,RASGRP1,PRKACB,SNX7,SLC27A2,SLC39A8,MAFB,SATB2,PDLIM3,MATN2,GRB10,INPP5F,TTC39A,PSPH |
| 3.061e-04 | -8.09 | GSE7852_LN_VS_THYMUS_TREG_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_UP | 187 | 34 | 17377 | 1707 |
CREB3L2,NMNAT3,ANTXR2,ABCC4,FGF13,RAB6B,UBASH3B,FOXN3,ITGA6,NFIA,CYP4V2,NUAK2,KIF5C,SCD,CCNG1,PRKCA,SNX9,TBC1D30,QPRT,HOPX,GPR15,FBXO32,TMEM154,RPS6KA2,PTPRJ,SEC16B,MARVELD2,RUNDC3B,TNFRSF1A,MAP7,IPCEF1,CPE,ETV1,NR3C2 |
| 3.061e-04 | -8.09 | GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_UP | MSigDB lists | GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_UP | 187 | 34 | 17377 | 1707 |
CREB3L2,MYO1D,PLBD2,AMOTL1,ITPRIP,ATP9A,BACE1,LMCD1,CADM2,NEDD4,ARHGAP44,TXNRD3,RND2,MPPED2,MARCH3,SLC2A12,MPDZ,NCAM1,GLIS1,BOD1,DPYSL5,SLC3A2,FZD4,FOXN3,TNS1,INTS6,NAALADL2,CLDN12,LAPTM4B,SEMA3C,CYP2U1,DOCK6,SFN,PCSK5 |
| 3.061e-04 | -8.09 | V$FOXD3_01 | MSigDB lists | V$FOXD3_01 | 187 | 34 | 17377 | 1707 |
TYRO3,BCL11B,THOC5,CHCHD7,PLAG1,GTF2IRD1,CREB5,EPHB1,IKZF2,NOVA1,NEO1,KCTD15,CHN2,RALGPS2,SLC10A7,FAM107B,BCL6,SGK1,PRICKLE2,MARCKS,ERRFI1,CKAP4,POU3F3,MSTN,CRIM1,NR6A1,NR4A1,SLC39A8,ATOH1,IKZF3,KLF12,GNAO1,NRP1,MEF2C |
| 3.061e-04 | -8.09 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | 187 | 34 | 17377 | 1707 |
EML5,MYCBP2,CYP2J2,ST6GAL1,SELL,KCTD12,SATB1,CD7,DDIT4,SKI,RNF141,ABLIM1,SIPA1L2,IGF1R,RALGPS2,MYC,MAP7,ADCY6,TSPAN13,MARCKS,EVL,PDK1,WLS,CYTH3,PLEKHA1,SESN1,TLR6,RERE,GSN,IFT81,WFS1,P4HA1,ZBTB20,ABCG1 |
| 3.064e-04 | -8.09 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN | 165 | 31 | 17377 | 1707 |
OR51B5,MEIS2,GAPDH,CFH,MYO10,OTOGL,SSX1,C1orf226,NKAIN2,VIM,AIG1,RAB38,INTS6,RBM11,FRK,FAM110B,PEAK1,NEDD4,TEX15,TM9SF2,NCKAP1L,L3MBTL4,ADAMTS3,SH3RF1,PRELID2,PCOLCE2,PLD1,FIG4,FIGN,DHCR7,CHMP4C |
| 3.064e-04 | -8.09 | GCATTTG,MIR-105 | MSigDB lists | GCATTTG,MIR-105 | 165 | 31 | 17377 | 1707 |
MXI1,PDE1B,PTPN13,ITGA6,GRID1,SLITRK5,SATB2,PRDM8,TJP1,CREB5,SPATS2L,FNDC3A,NRXN1,SP8,CPEB1,GRPEL2,MAP1B,KLF12,TM9SF2,FRAS1,BMP1,SRGAP1,NBEA,PRICKLE2,ACVR2A,CPXM2,KIAA0408,CDH2,ETV1,GLDC,MEF2C |
| 3.064e-04 | -8.09 | GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN | MSigDB lists | GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN | 165 | 31 | 17377 | 1707 |
SUSD3,DZANK1,GNG12,CARD6,CD55,ALOX5AP,PNP,FAM124A,WLS,BNIP3L,EPHB1,SNX9,RADIL,KREMEN1,CHD5,SLC19A2,DDX60L,TRPS1,HOMER3,IRS2,GPR160,PELI2,HK2,BCL6,TSC22D1,JAKMIP2,CAB39L,MET,FMNL2,CKAP4,ATP2B1 |
| 3.077e-04 | -8.09 | autonomic_ganglia-neuroblastoma | COSMIC cancer mutations | autonomic_ganglia-neuroblastoma | 4065 | 455 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,PPP4R4,ACVR1,TCP11L2,GRIK2,AASS,CNTNAP3,PRSS12,ATP8A1,DNAJC3,LDLR,PPFIBP2,TUBE1,FAM102B,NPM1,ADAMTS6,BCAN,DOCK3,KIAA1217,SNX9,NOS1AP,TRPS1,BAG3,FBXO32,TGFBR3,SLC22A18,PPFIA2,FAM168A,KCNS3,RCAN3,VWA5A,NKX2-1,GLDC,DCDC1,ACVR1C,TGFA,DSTN,NFIA,DEPTOR,ABCC2,FGF17,CA13,ARHGEF26,AHRR,ENPP1,NCKAP1L,BMP1,INPP5F,SERPINI1,UNC5B,DNHD1,C12orf77,SPOCK3,MEF2C,SEMA6B,SCN5A,LATS2,STOX2,INPPL1,CELSR1,ZHX3,TBC1D1,SCN8A,GABRB2,ITGA6,ZNF25,OPHN1,DYNC1I1,BBS9,MECOM,MCOLN2,SYCP2,FRY,KIAA1671,PIK3AP1,PDZD7,APLF,MYC,ZIC5,PRELID2,PRKG1,SREBF1,SRGAP1,CPXM2,TOX,CADPS2,FAM84B,DENND1C,NCAM1,GLIS1,PRR16,LRP12,RIMS2,RPL26,QSOX1,SLC37A1,KCNQ3,TBC1D8B,MYO10,STAT4,DCHS1,EFHC2,FASN,PACSIN3,RYR2,TTC30A,SMARCD3,NPC2,OR11H4,PLCB1,CACHD1,TEX15,TMCO3,PLEKHH2,SH3GL2,ISM1,CECR2,QPCTL,MPP2,SQLE,IQSEC2,SLFN5,TRPC3,CDH2,DOCK9,PLA2G4A,EPHA3,AMOTL1,RASAL2,ST14,ZNF311,LRRCC1,MSR1,PLXNA2,ADD2,PKP2,IL13RA1,COL14A1,ZFYVE9,TIAM2,CCDC120,EPB41L3,SPEG,DACT1,MAGEA3,NAP1L3,FAM155B,RAB27B,JAKMIP3,DNAH5,DOCK8,VNN2,SSH3,MYLK3,GARS,GAPDH,EBPL,TMEM43,SHANK2,PREX1,PRKCQ,ATF3,PYGO1,DSP,FGFR1,ZNF711,IKZF3,LAMB1,KLHL31,CTTNBP2,NR3C2,COBL,HACE1,MYO1D,PLSCR4,ANKRD13B,PLAG1,IPO5,PRSS35,ARL2,PSD3,GABRR2,CREB5,EPHB1,ZNF219,GDPD5,TSPAN17,COL27A1,NEO1,RGS17,LRRC55,MGAT1,AFF2,PCBP4,GAS2L3,SEPT3,GFI1,ZFP36L2,MED12L,B4GALT6,TRPM4,TMC7,PFKFB4,MN1,VAV3,ARAP2,CACNA1E,MCF2L2,RAPGEF2,PTPN13,ELOVL3,RASA3,GUCY1A2,SNTB1,HOXA1,ZIC1,PLOD2,TERT,OSBPL5,SLCO5A1,PGM2L1,SVIL,NEK11,GRIN2D,MYOM2,OCLN,LARP1,FOXA1,SLC43A1,TLL2,MPZL3,EXPH5,UGT8,TRIM16,PTPN21,FHDC1,LILRB1,SLC2A13,RBM11,SLCO3A1,HMCN1,RTN1,ARHGEF10L,SIPA1L2,EOMES,CPVL,ABI3BP,MARVELD2,TMEM86A,MPPED2,POF1B,JAKMIP2,TMEM132E,TLN2,MYRIP,NEB,SLIT2,RAPGEF5,RASGRP1,PDGFRB,TNK2,GPM6A,GCNT2,ABCC4,COL4A3,SPOCD1,YAP1,TMEM200C,CR2,CRYBG3,SERGEF,TMEM132B,GSN,HPSE,ITGBL1,MAP2,TECPR2,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,PPARGC1A,MLLT3,CHMP4C,PCSK5,LONRF1,PRKAA2,MOCOS,STXBP5L,FN1,SEC24D,SETBP1,RASL11B,LAMC3,GALNT13,SPINK5,FHOD3,PCDHB14,RNF180,GALNT1,ZBTB38,SLC30A4,ABCA5,FRAS1,SMTN,LRP6,NCEH1,FBXL2,MORN4,LRP3,NDUFA4L2,DPYSL5,RAX,PODXL2,PARD3B,GPSM1,TCEA3,SPATA13,PPFIA4,SDC3,OBSCN,DUSP9,STRADB,SDK1,PRDM1,B4GALNT3,MAPKAPK2,HEYL,FAT1,CSF1,RAI14,HK2,RAB31,PLD1,FNBP1L,XKR4,MME,CFH,DOCK1,CELSR3,PLEKHA5,LPCAT2,RHPN2,TDRKH,OR51B4,NTRK3,SEZ6L2,KIF21B,DENND3,TNKS1BP1,DOCK2,DDX60L,PCLO,ZSCAN5A,SCIN,FAM131B,TACC2,PPFIBP1,MYO3B,ZNF521,MAP7,WWC2,CLVS2,MET,ZNF460,HSPA2,NTNG1,CTH,GLI1,SUSD3,DPP10,PRAME,GCA,TMEM67,UROS,TDRD3,LRRC8B,PTPN6,TES,PRDM13,RNF125,VIM,AMIGO1,DOCK5,C1orf174,BCL11A,ZNF569,SMAD3,ARMC4,GBP1,ITGA2,SOHLH2,CTNND2,TNIK,PRSS16,BMPR2,ARHGEF11,CLGN,LRP4,MCTP2,COL4A5,IGF2BP2,CUEDC2,OVOL2,FOXP2,NKX6-1,KCNJ4,CHN2,FUT9,DSG2,KCNMB3,TSC22D1,KIAA0319,TRIM3,SGK1,TSPAN13,KIAA0408,IPCEF1,ESD,SLC45A3,TNFRSF11A,RBMS2,ATP2B1,CES3,RIN2,CARD6,LRRIQ1,CRIM1,CYTH3,LITAF,ASAP3,CCNG1,ARHGAP32,PALLD,TLR6,NAALADL2,LEPR,ILDR2,MAP1B,DKK1,ADAMTS17,MFSD9,FAT4,FBN1,MPP7,PRCP,MAP2K6,ZNF808,SLC22A15,KIF21A,RNF157,NPHP1,FILIP1 |
| 3.081e-04 | -8.08 | V$CIZ_01 | MSigDB lists | V$CIZ_01 | 217 | 38 | 17377 | 1707 |
TYRO3,BCL11B,BTC,CCDC148,CACNG3,CHCHD7,PLAG1,OVOL2,TNKS1BP1,IKZF2,COL27A1,PCDH7,TXNDC5,FOXP2,ATXN7L1,MAP1A,FLRT3,PDE4D,NCAM1,CKAP4,IGSF3,MEIS2,LRMP,HIP1,PRICKLE1,ZFPM2,BATF,ZIC1,BCL11A,ADAMTS17,TCF7L1,KLF12,CAB39L,ZBTB20,SEMA3A,HOXB9,FILIP1,FRMD5 |
| 3.110e-04 | -8.08 | CDH1 (cadherin 1) | protein interactions | 999 | 641 | 92 | 17029 | 1718 |
FAM171B,CGN,SORBS1,PLEKHA5,MYO1B,PKP2,COBLL1,NDRG2,KIAA1217,DDR1,TNKS1BP1,SNX9,STK24,CTNNA2,CCDC120,EPB41L3,BAG3,GPRIN1,MARVELD2,PPFIBP1,POF1B,STEAP3,DAB2IP,MARCKS,CTTN,MET,ENO1,DBN1,SSH3,PHLDB2,FER,ITGB7,SLC3A2,CEMIP2,TES,SHANK2,YAP1,PLEKHA1,FGFR1,MAGI3,PATJ,ARHGAP21,PTPRJ,SH3RF1,ALDOA,ADGRL2,CTNND2,LPP,INPPL1,BMPR2,STXBP6,ITGA6,SLK,TJP1,ISYNA1,RPL34,ABLIM1,NUMBL,EEF2,KIAA1671,DSG2,CRYBG1,INAVA,LIMCH1,SH3PXD2B,FAM84B,MYO6,FMNL2,ATP2B1,PDLIM7,PXN,FASN,PHACTR2,RACK1,SNAP25,ARHGAP32,UCHL3,PEAK1,BAIAP2,MPP7,RAI14,UACA,CLMN,SVIL,SLC1A5,FNBP1L,SFN,SHTN1,OCLN,ATP2B4,LARP1,DOCK9 |
| 3.112e-04 | -8.08 | LATS2 (large tumor suppressor kinase 2) | protein interactions | 26524 | 161 | 31 | 17029 | 1718 |
MOB1B,CGN,LATS2,PHLDB2,TBKBP1,AMOTL1,SORBS1,RASAL2,PTPN13,PLEKHA5,YAP1,WWC1,TJP1,PLEKHA1,SAV1,RADIL,NEDD4,PATJ,SKI,SIPA1L2,CPVL,KIAA1671,PPFIBP1,WWTR1,PLEKHG1,GRIP1,MPDZ,WWC2,TANC2,KIAA1549,PNMA2 |
| 3.124e-04 | -8.07 | protein O-linked glycosylation via threonine | biological process | GO:0018243 | 20 | 8 | 17256 | 1658 |
GALNT3,GALNT1,GALNT12,GALNT6,GALNT17,GALNT13,GALNT18,GALNT14 |
| 3.146e-04 | -8.06 | neuroblastoma | COSMIC cancer mutations | neuroblastoma | 4066 | 455 | 17385 | 1698 |
ARHGAP26,FAM171B,MYCBP2,PPP4R4,ACVR1,TCP11L2,GRIK2,AASS,CNTNAP3,PRSS12,ATP8A1,DNAJC3,LDLR,PPFIBP2,TUBE1,FAM102B,NPM1,ADAMTS6,BCAN,DOCK3,KIAA1217,SNX9,NOS1AP,TRPS1,BAG3,FBXO32,TGFBR3,SLC22A18,PPFIA2,FAM168A,KCNS3,RCAN3,VWA5A,NKX2-1,GLDC,DCDC1,ACVR1C,TGFA,DSTN,NFIA,DEPTOR,ABCC2,FGF17,CA13,ARHGEF26,AHRR,ENPP1,NCKAP1L,BMP1,INPP5F,SERPINI1,UNC5B,DNHD1,C12orf77,SPOCK3,MEF2C,SEMA6B,SCN5A,LATS2,STOX2,INPPL1,CELSR1,ZHX3,TBC1D1,SCN8A,GABRB2,ITGA6,ZNF25,OPHN1,DYNC1I1,BBS9,MECOM,MCOLN2,SYCP2,FRY,KIAA1671,PIK3AP1,PDZD7,APLF,MYC,ZIC5,PRELID2,PRKG1,SREBF1,SRGAP1,CPXM2,TOX,CADPS2,FAM84B,DENND1C,NCAM1,GLIS1,PRR16,LRP12,RIMS2,RPL26,QSOX1,SLC37A1,KCNQ3,TBC1D8B,MYO10,STAT4,DCHS1,EFHC2,FASN,PACSIN3,RYR2,TTC30A,SMARCD3,NPC2,OR11H4,PLCB1,CACHD1,TEX15,TMCO3,PLEKHH2,SH3GL2,ISM1,CECR2,QPCTL,MPP2,SQLE,IQSEC2,SLFN5,TRPC3,CDH2,DOCK9,PLA2G4A,EPHA3,AMOTL1,RASAL2,ST14,ZNF311,LRRCC1,MSR1,PLXNA2,ADD2,PKP2,IL13RA1,COL14A1,ZFYVE9,TIAM2,CCDC120,EPB41L3,SPEG,DACT1,MAGEA3,NAP1L3,FAM155B,RAB27B,JAKMIP3,DNAH5,DOCK8,VNN2,SSH3,MYLK3,GARS,GAPDH,EBPL,TMEM43,SHANK2,PREX1,PRKCQ,ATF3,PYGO1,DSP,FGFR1,ZNF711,IKZF3,LAMB1,KLHL31,CTTNBP2,NR3C2,COBL,HACE1,MYO1D,PLSCR4,ANKRD13B,PLAG1,IPO5,PRSS35,ARL2,PSD3,GABRR2,CREB5,EPHB1,ZNF219,GDPD5,TSPAN17,COL27A1,NEO1,RGS17,LRRC55,MGAT1,AFF2,PCBP4,GAS2L3,SEPT3,GFI1,ZFP36L2,MED12L,B4GALT6,TRPM4,TMC7,PFKFB4,MN1,VAV3,ARAP2,CACNA1E,MCF2L2,RAPGEF2,PTPN13,ELOVL3,RASA3,GUCY1A2,SNTB1,HOXA1,ZIC1,PLOD2,TERT,OSBPL5,SLCO5A1,PGM2L1,SVIL,NEK11,GRIN2D,MYOM2,OCLN,LARP1,FOXA1,SLC43A1,TLL2,MPZL3,EXPH5,UGT8,TRIM16,PTPN21,FHDC1,LILRB1,SLC2A13,RBM11,SLCO3A1,HMCN1,RTN1,ARHGEF10L,SIPA1L2,EOMES,CPVL,ABI3BP,MARVELD2,TMEM86A,MPPED2,POF1B,JAKMIP2,TMEM132E,TLN2,MYRIP,NEB,SLIT2,RAPGEF5,RASGRP1,PDGFRB,TNK2,GPM6A,GCNT2,ABCC4,COL4A3,SPOCD1,YAP1,TMEM200C,CR2,CRYBG3,SERGEF,TMEM132B,GSN,HPSE,ITGBL1,MAP2,TECPR2,ERN1,TNFRSF1A,AHNAK2,PIK3C2B,PPARGC1A,MLLT3,CHMP4C,PCSK5,LONRF1,PRKAA2,MOCOS,STXBP5L,FN1,SEC24D,SETBP1,RASL11B,LAMC3,GALNT13,SPINK5,FHOD3,PCDHB14,RNF180,GALNT1,ZBTB38,SLC30A4,ABCA5,FRAS1,SMTN,LRP6,NCEH1,FBXL2,MORN4,LRP3,NDUFA4L2,DPYSL5,RAX,PODXL2,PARD3B,GPSM1,TCEA3,SPATA13,PPFIA4,SDC3,OBSCN,DUSP9,STRADB,SDK1,PRDM1,B4GALNT3,MAPKAPK2,HEYL,FAT1,CSF1,RAI14,HK2,RAB31,PLD1,FNBP1L,XKR4,MME,CFH,DOCK1,CELSR3,PLEKHA5,LPCAT2,RHPN2,TDRKH,OR51B4,NTRK3,SEZ6L2,KIF21B,DENND3,TNKS1BP1,DOCK2,DDX60L,PCLO,ZSCAN5A,SCIN,FAM131B,TACC2,PPFIBP1,MYO3B,ZNF521,MAP7,WWC2,CLVS2,MET,ZNF460,HSPA2,NTNG1,CTH,GLI1,SUSD3,DPP10,PRAME,GCA,TMEM67,UROS,TDRD3,LRRC8B,PTPN6,TES,PRDM13,RNF125,VIM,AMIGO1,DOCK5,C1orf174,BCL11A,ZNF569,SMAD3,ARMC4,GBP1,ITGA2,SOHLH2,CTNND2,TNIK,PRSS16,BMPR2,ARHGEF11,CLGN,LRP4,MCTP2,COL4A5,IGF2BP2,CUEDC2,OVOL2,FOXP2,NKX6-1,KCNJ4,CHN2,FUT9,DSG2,KCNMB3,TSC22D1,KIAA0319,TRIM3,SGK1,TSPAN13,KIAA0408,IPCEF1,ESD,SLC45A3,TNFRSF11A,RBMS2,ATP2B1,CES3,RIN2,CARD6,LRRIQ1,CRIM1,CYTH3,LITAF,ASAP3,CCNG1,ARHGAP32,PALLD,TLR6,NAALADL2,LEPR,ILDR2,MAP1B,DKK1,ADAMTS17,MFSD9,FAT4,FBN1,MPP7,PRCP,MAP2K6,ZNF808,SLC22A15,KIF21A,RNF157,NPHP1,FILIP1 |
| 3.149e-04 | -8.06 | cell-substrate junction | cellular component | GO:0030055 | 405 | 60 | 18223 | 1724 |
ARHGAP26,EFNB2,SORBS1,MRC2,ITGA6,ARHGAP22,ARL2,NPM1,ENAH,SORBS3,RPL13A,PPFIBP1,RPS11,FLRT3,ITGB3,EHD3,SCARF2,MARCKS,CTTN,TLN2,RRAS2,TSPAN9,FES,PDGFRB,FZD1,RPS13,EPB41L5,PAK1,PDLIM7,PHLDB2,SYNPO2,EVL,PXN,TES,CAPN5,ASAP3,FHL2,FERMT2,VIM,TNS1,PALLD,SNTB1,PEAK1,PTPRC,GSN,LMLN,DOCK7,RPL12,RND3,FAT1,PTK7,ITGA2,SVIL,RPL4,SPRY4,NRP1,CDH2,CSRP2,MME,LPP |
| 3.186e-04 | -8.05 | GO_REGULATION_OF_NEUROTRANSMITTER_LEVELS | MSigDB lists | GO_REGULATION_OF_NEUROTRANSMITTER_LEVELS | 180 | 33 | 17377 | 1707 |
DOC2A,SLC6A9,PDE1B,SYT12,ABAT,SLC1A3,APBA1,SYT14,NRXN1,ZNF219,KCNC4,PFN2,PCLO,PPP1R9A,UNC13B,PPFIA2,LIN7A,CADPS2,STXBP1,RIMS2,RAB3B,LRRK2,SNAP25,SNCA,TRIM9,DAGLA,KCNMB4,PTPRN2,MAOA,SEPT5,TC2N,MEF2C,SNPH |
| 3.186e-04 | -8.05 | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_UP | 180 | 33 | 17377 | 1707 |
SIDT1,BMPR2,GPR65,RASL11B,TJP1,DNER,INPP1,SLCO3A1,HOPX,PLS3,RUNDC3B,SNX10,PTPRE,ZFP36L2,KCNQ3,COL4A3,SLC39A8,ZDHHC15,CALCRL,VIM,ATP11A,OR11H4,ARRDC4,DSP,ARHGAP21,ICA1,SH3RF1,ERN1,SRD5A3,PAM,MYOM2,PLD1,NEUROG2 |
| 3.186e-04 | -8.05 | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN | MSigDB lists | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN | 180 | 33 | 17377 | 1707 |
PRSS16,LGALS3,CELSR3,SEC24D,PSTPIP2,STXBP6,UGDH,MORC4,SLC36A4,SLC7A2,CHSY1,UBTD2,MTUS1,RPS6KA2,PPFIBP1,REEP1,ITGB3,LMAN2,PDE4D,NCAM1,ZNF518B,SLC36A1,LRRK2,SHISA2,SATB2,ATP11A,DSP,C4orf19,PLCB1,HERPUD1,RND3,TECPR2,MAOA |
| 3.205e-04 | -8.05 | GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | 225 | 39 | 17377 | 1707 |
CREB3L2,BCL11B,RUNX2,PLAG1,OTX1,GATA3,CEBPA,STAT5B,GRHL1,GATA2,MYC,SREBF1,TFAP2A,EBF4,POU2F2,ETV1,CEBPD,RAX,ATF4,MEIS2,NR6A1,NR4A1,NFIA,MAFB,MEF2B,ATOH1,BATF,ZIC1,CEBPB,EBF1,HEYL,HOXD13,KLF5,DBP,NKX2-8,SIX2,DDIT3,FOXA1,MEF2C |
| 3.205e-04 | -8.05 | GO_TELENCEPHALON_DEVELOPMENT | MSigDB lists | GO_TELENCEPHALON_DEVELOPMENT | 225 | 39 | 17377 | 1707 |
BCL11B,SCN5A,GNG12,ROBO2,FGF13,AKAP5,BCAN,SKI,FOXP2,NUMBL,EOMES,TACC2,LHX6,LRP6,DAB2IP,DNAH5,SLIT2,POU3F3,NKX2-1,DISC1,LRRK2,VLDLR,SLITRK5,EFHC1,ATOH1,PLCB1,FGFR1,TSKU,NRG3,FAT4,LAMB1,PTPRS,DLX2,BMP4,OXTR,NRP1,SEMA3A,CDH2,ATP2B4 |
| 3.220e-04 | -8.04 | regulation of lipid biosynthetic process | biological process | GO:0046890 | 169 | 31 | 17256 | 1658 |
PRKAA2,FGFR4,SORBS1,MVK,MVD,LDLR,FASN,AGAP2,SCD,RACK1,PIBF1,ABHD6,BMP6,GPLD1,CYP51A1,TRIB3,IDI1,HMGCS1,INSIG1,PRKCD,STARD4,SREBF1,TNFRSF1A,SQLE,PPARGC1A,DHCR7,GFI1,SLC45A3,SNAI2,ABCG1,HMGCR |
| 3.223e-04 | -8.04 | SNF5_DN.V1_DN | MSigDB lists | SNF5_DN.V1_DN | 151 | 29 | 17377 | 1707 |
RGS16,FGF13,PRSS12,ATP9A,EFNA3,PKP2,CACNB4,TPD52L1,FOXG1,DSP,SLCO3A1,SNCA,EFEMP1,TMEM53,SPEG,RIMKLB,RPS6KA2,KCNAB1,SLC30A4,SH3RF1,DSG2,PRKG2,MAPK13,PCOLCE2,LOXL4,NIPAL2,HOXB9,CNTN1,CTH |
| 3.223e-04 | -8.04 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_UP | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_UP | 151 | 29 | 17377 | 1707 |
PDLIM7,GXYLT2,ALDH2,ALOX5AP,KLHL4,LSM11,DNAJC6,CEBPA,TCERG1L,ADSSL1,GPR137C,CA13,SKI,CCDC120,GBGT1,ID3,SYCP2,KCNAB1,PMEPA1,ZNF440,RASGRF2,C12orf60,SH3BP4,CNNM2,MOXD1,SMAD6,CDH2,CHMP4C,ULBP1 |
| 3.223e-04 | -8.04 | TAAWWATAG_V$RSRFC4_Q2 | MSigDB lists | TAAWWATAG_V$RSRFC4_Q2 | 151 | 29 | 17377 | 1707 |
TYRO3,ARHGAP26,MID2,ARAP2,INPPL1,USP2,RNF145,FGF13,GRB14,NR4A1,TCEA3,MORC4,STRADB,SATB2,SNAP25,SEMA6A,BEX2,PPP2R3A,TRPS1,KIAA0355,GNB4,ALDOA,ACVR2A,HRK,PPARGC1A,SHOX2,NEB,CTNND2,FILIP1 |
| 3.233e-04 | -8.04 | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 6176 | 668 | 17385 | 1698 |
DOC2A,ADAL,FLVCR2,GRIK2,AASS,PRSS12,RECK,DNAJC3,LSM11,FAM102B,NPM1,ALG1L,STAT5B,CADM2,BCAN,DOCK3,KIAA1217,EYA4,NOS1AP,TGFBR3,COG3,TSHR,DCC,KLHL23,LRRK2,ELMOD1,ABCC2,F12,MFSD6,PYCR1,ATP7B,MAP9,ALDOA,ERCC5,INPP5F,ZBTB20,TMEFF2,CRYL1,MEF2C,CARS,SCN5A,STOX2,CYP2J2,ITGA6,TJP1,FOXG1,BBS9,HPCAL4,SYCP2,FRY,CACNB2,TOX,DENND1C,NCAM1,MOXD1,GFRA1,LRP12,SLC37A1,KCNQ3,MYO10,SPATA6,ARID5B,ZNF605,FASN,FHL2,RYR2,HIP1,AIG1,ZBBX,TAF4B,DHX32,BEX4,CACHD1,TEX15,TMCO3,SH3GL2,EMILIN2,CLMN,TRPC3,DOCK9,TFCP2L1,DNM3,ZNF516,MYO1B,LRRCC1,PKP2,IL13RA1,GRK6,SLC19A2,EPB41L3,TLR3,COL25A1,CNKSR3,DACT1,MAGEA3,ALDH1L1,DNAH5,MYT1,SCN3A,DOCK8,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,KCNH5,TRAM1L1,ADCY1,DSP,ZNF618,FGFR1,MAGI3,GJC1,SLC39A14,ENTPD1,ARHGAP21,IQCH,WFS1,GPR160,WWTR1,LAMB1,INPP4B,PAM,PLEKHG1,ALG11,PLD5,DBP,C2orf88,CCDC148,FARP1,ESRP1,BACE1,IPO5,PSD3,CREB5,PKN1,EPHB1,BEX2,COL27A1,NEO1,MYO6,ZFP36L2,MED12L,FES,PARP9,ULBP1,TRPM4,PDLIM7,MN1,RAPGEF2,ELOVL3,ATP11A,HEG1,GALNT3,PTPRC,TRIB3,NSD1,PCDHB7,OSBPL5,NEK11,BMP4,HK1,DOCK6,DCBLD1,FOXA1,PHC1,TLL2,PHACTR3,NMNAT3,FGF13,SYT12,ASS1,MGAT5B,ITPR2,FSTL5,RUFY4,CPNE2,FKBP9,KCNAB1,KCNN2,TMEM86A,ITGB3,TMEM143,COL19A1,JAKMIP2,KIAA1614,ETV1,NEB,PGBD5,SLC3A2,GCNT2,MARK1,ATF4,ABCC4,COL4A3,SPOCD1,ANK2,PLEKHA1,TCERG1L,CRYBG3,TSKU,INSIG1,KLF12,MAP2,GNB4,TECPR2,TNFRSF1A,PIK3C2B,MLLT3,LONRF1,PRKAA2,KCNV1,RUNX2,ITPRIP,SETBP1,IL18R1,DOK5,FHOD3,HSPA12B,KIAA1958,IGF1R,ABCA5,BCHE,ZNF440,FRAS1,HS3ST5,SMTN,ADCY6,SLCO4C1,FAR2,NIPAL2,FGFR4,CHSY3,UNC5C,BTNL9,RNF170,GPSM1,TMTC4,WDR25,OBSCN,SLITRK5,PDE8A,SDK1,KHDRBS2,TEX9,GPR19,BAIAP2,NEGR1,TBC1D2,SIX2,SFN,CFH,AKAP5,DOCK1,RHPN2,RNF24,ZNF83,NTRK3,SLC7A2,FAM198B,LPIN3,SEZ6L2,KIF21B,DENND3,RADIL,TNKS1BP1,PPP1R9A,SEMA6A,PCLO,DDX60L,TBC1D19,FAM131B,TACC2,MYO3B,BCL6,MYH15,CLVS2,SCN2A,INTU,TMEM67,THSD4,PRDM13,ACO1,FRK,C4BPB,IFT81,RANBP2,NRG3,PTPRJ,SUSD4,CTNND2,CNTN1,HEY1,MAN2B2,PCDH18,DYRK3,SLC6A9,KLHL13,RUSC2,APBB1,MCTP2,RASD1,PPP2R3A,TTC1,FOXP2,MAP1A,RASD2,KCNMB3,TSC22D1,PRICKLE2,KIAA0408,KLF9,PCK2,KIAA1211,ATP2B1,CES3,DLGAP1,PPP1R3D,MICAL2,LRRIQ1,NUAK2,FERMT2,PALLD,MGMT,HOMER3,DKK1,DDAH1,DOCK7,FAT4,FBN1,L3MBTL4,ZNF214,DLG2,SLC22A15,SLC1A5,TBC1D4,KIF1B,FILIP1,ZNF235,FAM171B,MYCBP2,PLBD2,TTC39B,LGR4,LDLR,PPFIBP2,AARS,ZFYVE28,CFHR1,SLC16A2,SERINC2,KCNS3,NDUFB8,ATRNL1,BEND4,MAGEA6,VWA5A,PLTP,TBC1D8,DCDC1,ACVR1C,WISP3,NR6A1,FAM84A,LRMP,TNS1,ACVR2B,ZDHHC14,SFXN1,SH3RF1,NCKAP1L,ENPP6,CCBE1,BMP1,MAPK13,UNC5B,TANC2,NRP1,LRFN5,MRC2,FAM124A,CELSR1,PTPRD,TBC1D1,SCN8A,GABRB2,MRPL22,SLC1A3,APBA1,ADSSL1,TNFRSF19,MECOM,MTUS1,ABLIM1,KIAA1257,SLC7A11,MYC,PRELID1,CPXM2,GRIP1,SLC16A9,GPR161,IGSF3,PTCH2,TBC1D8B,SLC36A1,PLEKHA8,COL4A4,VLDLR,RAPGEF4,DCHS1,PACSIN3,TTYH2,TTC30A,CDC42BPA,FAM162A,PLEKHH2,PKN3,PMEPA1,CECR2,THBS4,LRRIQ3,MATN2,DYNC2LI1,MPP2,SFMBT1,SLFN5,AMPD1,EPHA3,PLA2G4A,TCTN2,RASAL2,RHOD,GPR65,CCDC110,PLXNA2,CHUK,COL14A1,DDR1,ZFYVE9,TIAM2,CCDC120,ZNF827,SPEG,TMEM53,ALDOC,SCRN1,PDE4D,SERPINH1,TRDMT1,VNN2,TMEM43,PANK1,PREX1,PRKCQ,CBY1,SATB2,PYGO1,ATP10D,DCBLD2,IKZF3,CTTNBP2,STON2,MID1,COBL,HACE1,ANO10,PLSCR4,MXI1,CCNJL,HERC5,GABRR2,RGS7,TPD52L1,NEDD4,RASSF8,LRRC55,MGAT1,GPR155,SGK3,RALGAPA2,SLC6A15,DYNC2H1,TBC1D9,SMPDL3A,B4GALT6,TMC7,VAV3,ALDH2,ARHGEF28,ARAP2,PXN,SYNPO2,CACNA1E,MPP1,PTPN13,ZDHHC15,ZIC1,MCC,SVIL,GRIN2D,MYOM2,TNFRSF17,SLC43A1,ATP1A3,NUDT17,EXPH5,ACSL1,KIF5A,ACTL8,PTPN21,UGDH,IKZF2,KREMEN1,HMCN1,SLCO3A1,RTN1,LGI2,ADPRHL1,ARHGEF10L,SIPA1L2,PPM1E,ANKFN1,TRPC1,PCOLCE2,PTPRE,OR2W3,PDGFRB,RASGRP1,CYP1B1,ATL1,SESN2,JPH1,SERGEF,TMEM132B,GSN,AK1,GPRC5B,TNFSF4,APBA2,PCSK5,UST,BCL11B,SV2B,ZNF395,FN1,RHOBTB1,BVES,LAMC3,GALNT13,FAM81A,SATB1,PCDHB14,RNF141,CA2,LIMCH1,NCEH1,CAND2,NOS3,CDH26,GPR176,PCDH10,PODXL2,SLITRK2,EDEM3,WWC1,PRDM1,B4GALNT3,AMDHD1,STEAP1,GLCE,KIAA0355,FAT1,RAI14,TMEM117,EGFL7,FNBP1L,XKR4,DMXL2,EML5,ZSWIM5,CELSR3,PSTPIP2,PLEKHA5,HECW2,MORC4,COL18A1,COBLL1,DOCK2,SCIN,COL22A1,PDZD8,UNC13B,SETDB2,CDC14B,PPFIBP1,ZNF521,MAP7,ACVR2A,STEAP3,POU2F2,MET,ZNF460,SEMA6C,PTPRU,SYNJ2BP,CD40,DOCK5,TPK1,BCL11A,ARMC4,ZNF93,LMLN,TRIM34,KPNA3,TMPRSS9,CYP2U1,LIFR,ENO2,PRSS16,ARHGEF11,CLGN,REL,LRP4,SSX1,CLSTN2,COL4A5,OVOL2,SEL1L3,BMP6,SYDE2,PRKCD,DSG2,EHD3,TRIM3,AFAP1L2,IPCEF1,IQGAP3,RBMS2,CARD6,RIN2,MSX1,RAB3B,NR4A1,ESRRG,SYBU,GRID1,OGDHL,MEI1,CCNG1,ARHGAP32,ZFPM2,GALNT14,NAALADL2,MAP1B,RERE,GPR37,DPY19L2,ADAMTS17,NACC2,RND3,PRCP,THSD7B,UACA,KIF21A,IL9R,NPHP1,SNPH |
| 3.240e-04 | -8.03 | epithelial cell morphogenesis | biological process | GO:0003382 | 30 | 10 | 17256 | 1658 |
BCL11B,EPB41L5,ID1,ST14,COL18A1,POF1B,MET,PALLD,ARHGEF26,HEG1 |
| 3.243e-04 | -8.03 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 195 | 35 | 17377 | 1707 |
LGALS3,IL15,CHCHD7,PRSS12,GCAT,RECK,PLEKHA5,CYP4V2,GATA3,KCTD12,PRKCA,IL18R1,EYA4,TXNDC5,MCOLN2,BAG3,SOAT2,SEMA4F,EOMES,TMEM37,FHIT,ERRFI1,SNX10,ANTXR2,SKAP2,DSTN,PTPN13,MGST3,LITAF,GSTO1,PRDM1,DOCK5,ENPP1,MYADM,NRP1 |
| 3.251e-04 | -8.03 | GO_REGULATION_OF_BLOOD_CIRCULATION | MSigDB lists | GO_REGULATION_OF_BLOOD_CIRCULATION | 287 | 47 | 17377 | 1707 |
SCN5A,CACNG3,BMPR2,BVES,CYP2J2,PKP2,ITPR2,P2RY1,CACNB4,NOS1AP,HOPX,KCNJ4,SCN1B,CACNB2,DSG2,SREBF1,ADCY6,TRPC1,PDE4D,CHRM3,ATP2B1,NOS3,HMGCR,TRPM4,GSTM2,KCNIP3,TMEM65,ANK2,RYR2,GSTO1,PRKCQ,ATP1B1,KCND3,DOCK5,ASPH,DSP,GJC1,KCNK15,KCNMB4,GNAO1,ADRB1,OXTR,TPM1,SEMA3A,CACNA2D1,ATP2B4,ATP1A3 |
| 3.259e-04 | -8.03 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_DN | 89 | 20 | 17377 | 1707 |
EPB41L5,FAM171B,FGF13,GRB14,FAM84A,MYO1B,ARID5B,EFEMP1,AHNAK2,ZNF704,SH3BP4,KIAA0513,NBEA,UACA,TSPAN12,RAB27B,MMP16,CTNND2,MME,PARP9 |
| 3.281e-04 | -8.02 | ACCTGTTG_UNKNOWN | MSigDB lists | ACCTGTTG_UNKNOWN | 144 | 28 | 17377 | 1707 |
RWDD2A,DOC2A,KCNV1,NUDT10,SCN5A,MRC2,KCNQ3,SEC24D,SOX21,COL18A1,TJP1,FGF17,PKN1,USP30,SEL1L3,EYA4,BCL11A,SNCA,MTUS1,COL25A1,PCBP4,SAMD11,TSC22D1,SHF,SHOX2,NKX2-8,MMP16,NR3C2 |
| 3.306e-04 | -8.01 | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_DN | 173 | 32 | 17377 | 1707 |
SERINC5,PNP,SCAMP1,NR4A1,UBASH3B,WLS,PTPN13,FOXN3,CYTH3,YPEL2,NRN1,VIM,CHSY1,PRKCA,SNX9,GPR15,ENTPD1,PLAGL1,SH3RF1,TERT,CSF1,XBP1,PCGF2,P4HA1,PTPRS,MED7,TANC2,VWA5A,SLC1A5,NRP1,TBC1D4,NEB |
| 3.307e-04 | -8.01 | GO_GOLGI_APPARATUS | MSigDB lists | GO_GOLGI_APPARATUS | 1368 | 172 | 17377 | 1707 |
ATP8A1,LDLR,NDRG2,CHAC1,MGAT5B,BCAN,SNX9,NCS1,CHST10,SLC9A7,SEC16B,GRHL1,RAB26,KCNS3,JAKMIP2,TMED9,CTTN,COG3,PACSIN1,CPE,RASGRP1,ATL1,CD55,GCNT2,ERGIC1,KCNIP3,TGFA,WLS,LRRK2,FEZ1,GPC6,SH3RF1,ATP7B,B3GALT2,TNFRSF1A,BMP1,DSEL,SPRY4,CRYL1,PCSK5,UST,INPPL1,SEC24D,ST6GAL1,DHCR24,GALNT13,CHSY1,APBA1,MECOM,MTUS1,GBGT1,GALNT1,ABCA5,BACE2,HS3ST5,PRKG1,SREBF1,LRP6,LMAN2,ST8SIA1,NCAM1,NOS3,CHSY3,FGFR4,PAK1,IL17RD,QSOX1,RHOQ,PLEKHA8,MGAT4B,FASN,GPSM1,SDC3,HIP1,ST6GALNAC3,RABAC1,SNAP25,B4GALNT3,CLN5,GLCE,SH3GL2,PLAGL1,PMEPA1,PKN3,QPCTL,RAB31,PLD1,FNBP1L,RNF122,PLA2G4A,PCSK1N,ID1,DNM3,SCAMP1,IL15,RNF144A,CCDC110,GALNT12,GALNT6,LPCAT2,MYO1B,XYLT1,RGS20,RNF24,FAM198B,TLR3,UNC13B,NBEA,PROS1,JAKMIP3,RAB27B,CLVS2,PERP,B3GALT1,TMEM43,ACO1,CBY1,RAB38,JAM3,GABARAPL1,SNCA,SLC39A14,ARHGAP21,GBP1,PAM,KLF5,HS3ST3B1,RAB30,HACE1,SERINC5,IGFBP6,ATP9A,FZD8,BACE1,IPO5,CLSTN2,GAS6,NDFIP2,NEDD4,NEO1,RAB11FIP5,MGAT1,FUT9,STC2,TFAP2A,FIG4,DYNC2H1,MYO6,FES,PCSK6,B4GALT6,TRPM4,RAB6B,CYTH3,SYBU,LITAF,ZDHHC15,ARHGAP32,FNDC3A,TLR6,GALNT14,GALNT3,ICA1,RND3,ACER2,AKT3,SLC1A5,CERS1,MMP16,B4GALT7,ATP1A3,ABCG1 |
| 3.316e-04 | -8.01 | GGGYGTGNY_UNKNOWN | MSigDB lists | GGGYGTGNY_UNKNOWN | 625 | 88 | 17377 | 1707 |
AVPI1,KIF5A,GRK6,CANX,RBM11,PRR7,SEMA6A,DACH2,RTN1,EPB41L3,SPEG,NELL2,ABI3BP,PPFIA2,TMEM143,POF1B,CNNM2,PERP,IGFBP3,ATL1,TUBA1A,VIM,SLC25A28,ATP10D,BCL11A,SLC7A1,TCF7L1,SH3RF1,PTK7,ATP7B,ADRB1,KLF5,DBP,RAB30,TYRO3,FARP1,BMPR2,LGALS3,SCN8A,APBB1,OVOL2,CHD5,BMP6,DDIT4,MCU,ATXN7L1,HMGCS1,FRY,RALGPS2,PIK3AP1,NOVA2,PCBP4,EIF1,FBXL2,NCAM1,VGLL4,PRR16,FES,RNF152,B4GALT6,DPYSL5,PDLIM7,BDNF,PXN,RHOQ,RNF170,RAB6B,MGST3,MGAT4B,NUAK2,EFNA3,PRRG1,WDR25,STRADB,PLS1,CTTNBP2NL,UCHL3,MAP1B,MYADM,MPP2,NXPH4,PAX9,SHOX2,SFN,SLC16A10,ATP1A3,SLC43A1,DOCK9 |
| 3.322e-04 | -8.01 | MEL18_DN.V1_DN | MSigDB lists | MEL18_DN.V1_DN | 137 | 27 | 17377 | 1707 |
EPHA3,COL9A3,UNC5C,VAV3,TRIM2,SKAP2,ZCCHC24,ESRP1,PKP2,NDRG2,PLCB1,COL14A1,DOK5,EYA4,AK1,BAG3,EPB41L3,CHN2,CA2,PCGF2,MPPED2,TFAP2A,MAP7,SERPINI1,PIK3C2B,GULP1,PPARGC1A |
| 3.322e-04 | -8.01 | GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 137 | 27 | 17377 | 1707 |
CXCR5,VAV3,EVL,PDK1,RNF144A,REL,PTPN13,RAPGEF4,LITAF,SELL,NPM1,PLEKHA1,ATXN7L1,RALGPS2,TRIM34,BACH2,MPP7,TACC2,MYC,INPP4B,RGS10,ZDHHC23,SGK3,LAPTM4B,TOX,VWA5A,SLC43A1 |
| 3.327e-04 | -8.01 | substrate adhesion-dependent cell spreading | biological process | GO:0034446 | 41 | 12 | 17256 | 1658 |
TYRO3,FER,ITGB7,FN1,BVES,FZD4,ITGB3,LAMB1,FERMT2,NRP1,PEAK1,RADIL |
| 3.345e-04 | -8.00 | regulation of cartilage development | biological process | GO:0061035 | 65 | 16 | 17256 | 1658 |
RUNX2,BMPR2,NKX3-2,CHADL,WNT11,ZNF219,BMP6,TRPS1,SCIN,SMAD3,EFEMP1,BMP1,BMP4,SHOX2,SNAI2,SIX2 |
| 3.362e-04 | -8.00 | MODULE_95 | MSigDB lists | MODULE_95 | 507 | 74 | 17377 | 1707 |
DMXL2,BTC,CELSR3,DOCK1,GRIK2,VAMP8,MCOLN3,TDRKH,NTRK3,SEZ6L2,NRXN1,DENND3,CACNB4,TXNDC5,ADPRHL1,SIPA1L2,TYMP,PPFIA2,POF1B,SNX10,ZNF365,PERP,SEMA6C,PRKACB,SKAP2,KLHL3,TTC22,SLC25A28,SERGEF,ATP10D,TPK1,GSN,AK1,SH3RF1,EIF4EBP1,NRP1,SUSD4,COBL,PURG,UST,KCNV1,ANO10,RGS16,SEMA6B,GRB14,OPHN1,GALNT13,P2RY1,INPP1,DDIT4,KCNJ4,MAP1A,MCF2L,DSG2,STC2,KIAA0319,KCNMB3,STXBP1,TBC1D8B,COL4A4,ASAP3,SLITRK5,TAF4B,PALLD,TERT,ZNF214,PELI2,CECR2,PLXDC2,FMO4,NXPH4,THAP10,XKR4,TLL2 |
| 3.367e-04 | -8.00 | WGGAATGY_V$TEF1_Q6 | MSigDB lists | WGGAATGY_V$TEF1_Q6 | 343 | 54 | 17377 | 1707 |
CGN,CCDC148,AVPI1,RASAL2,IGFBP6,BMPR2,FGF13,GALNT12,SCN8A,COL4A5,COLEC10,DDR1,RADIL,TSPAN17,PRRG4,NEDD4,PLS3,ADPRHL1,FOXP2,ZNF827,SPEG,DACT1,PPFIBP1,TMEM86A,SCARF2,TSPAN9,FGFR4,GPM6A,MYLK3,ATF4,NR4A1,PRDM1,CTTNBP2NL,MBNL2,DSP,ZIC1,BCL11A,SMAD3,NAP1L5,NSD1,PTPRJ,MYADM,SH3RF1,ITGA2,C1orf21,SH3BGRL2,BMP4,TPM1,MAPK10,LIFR,MLLT3,MID1,DDIT3,RAB30 |
| 3.371e-04 | -8.00 | WW_dom_sf | interpro domains | IPR036020 | 46 | 13 | 18492 | 1811 |
BAG3,PLEKHA5,APBB1,WWTR1,HECW2,YAP1,WWC1,WWC2,TCERG1L,SAV1,MAGI2,MAGI3,NEDD4 |
| 3.412e-04 | -7.98 | GO_ENDOTHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_ENDOTHELIAL_CELL_DIFFERENTIATION | 70 | 17 | 17377 | 1707 |
ACVR1,ID1,BMPR2,RAPGEF2,COL18A1,TJP1,ACVR2B,ARHGEF26,HEG1,MYADM,MARVELD2,GSTM3,PTPRS,PDE4D,MET,NRP1,HEY1 |
| 3.412e-04 | -7.98 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | 70 | 17 | 17377 | 1707 |
EFNB2,CD55,WLS,GJB2,CRIP2,PKP2,TNFRSF19,DSP,F3,DDIT4,EPCAM,GHR,PAM,FAM107B,ZFP36L2,PERP,CRYL1 |
| 3.420e-04 | -7.98 | GSE2706_R848_VS_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_LPS_8H_STIM_DC_DN | 166 | 31 | 17377 | 1707 |
UNC5C,LATS2,NBL1,TTC39B,PNRC1,IL15,C1orf226,RGS20,SLC2A13,FNDC3A,PEAK1,SLCO3A1,PGAP1,DDX60L,PRRG4,PLS3,EPB41L3,TCF7L1,GYPC,PMAIP1,GBP1,CCNA1,GRB10,TMOD2,PLD1,TNFSF4,SNX10,COBL,STOM,LAMP3,ABCG1 |
| 3.420e-04 | -7.98 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_UP | 166 | 31 | 17377 | 1707 |
UST,GCA,GPM6A,LPAR2,EVL,CLGN,SH2D2A,CHCHD7,TBC1D1,PLAG1,PKP2,SATB2,VIM,DENND3,SLC19A2,MAGI3,BAIAP2,EBF1,CPNE2,KLF12,FAT1,OSBPL5,WWTR1,SGK1,STEAP3,SLC22A15,TLN2,NRP1,TLR4,STXBP1,SPRY2 |
| 3.449e-04 | -7.97 | regulation of blood circulation | biological process | GO:1903522 | 294 | 47 | 17256 | 1658 |
SCN5A,CACNG3,FGF13,BMPR2,BVES,CYP2J2,PKP2,ITPR2,CACNB4,NOS1AP,KCNJ4,IRX5,KCNN2,SCN1B,CACNB2,DSG2,EHD3,SREBF1,TRPC1,PDE4D,ATP2B1,CHRM3,NOS3,TRPM4,KCNIP3,GSTM2,TMEM65,ANK2,RYR2,GSTO1,KCND3,ATP1B1,DSP,DOCK5,ASPH,GJC1,KCNK15,KCNMB4,GNAO1,APELA,ADRB1,OXTR,TPM1,SEMA3A,CACNA2D1,ATP2B4,ATP1A3 |
| 3.454e-04 | -7.97 | JOHNSTONE_PARVB_TARGETS_3_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_UP | 400 | 61 | 17377 | 1707 |
ARHGAP26,TNIK,NBL1,ACSL1,CELSR1,ENO2,FN1,LGR4,CD276,VAMP8,LDLR,MORC4,COL18A1,SCD,SFXN3,SEZ6L2,FHOD3,DDIT4,EPCAM,NAV1,PMAIP1,FRAS1,PPFIBP1,STEAP3,MARCKS,LOXL4,CTTN,TBC1D9,ERRFI1,RRAS2,TLR4,KLHL29,PTPRE,CEBPD,PNMA2,FADS1,ATL1,MICAL2,CD55,PNRC1,TMEM43,WLS,MGAT4B,NFE2L1,LITAF,VIM,RABAC1,NPC2,MFSD6,SNTB1,DSP,FGFR1,CEBPB,SMAD3,GSN,CSF1,ITGA2,AHNAK2,UACA,PLD1,ATP2B4 |
| 3.466e-04 | -7.97 | polypeptide N-acetylgalactosaminyltransferase activity | molecular function | GO:0004653 | 20 | 8 | 17224 | 1680 |
GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT18,GALNT14 |
| 3.466e-04 | -7.97 | negative regulation of biological process | biological process | GO:0048519 | 5221 | 563 | 17256 | 1658 |
THOC5,GRIK2,RECK,DNAJC3,NPM1,CTBP2,STAT5B,CEBPA,CHAC1,ABHD6,EYA4,SKI,TXNDC5,BAG3,PPP1R26,TGFBR3,IKZF5,RAP2A,POU3F3,NKX2-1,MEIS2,DCC,LRRK2,NFIA,FEZ1,PRKAR2B,F12,PYCR1,ENPP1,ADRB1,ARHGAP28,ZBTB20,CAB39L,TMOD2,ERCC5,INPP5F,TPM1,TMEFF2,MEF2C,LATS2,ITGA6,FOXG1,SYCP2,BNIP1,FRY,PAIP2B,BACE2,FLRT3,SRGAP1,JAM2,GLIS1,STXBP1,RPS23,ZNF385A,HMGCR,BDNF,ARID5B,FHL2,RYR2,CALCRL,SHISA2,CPEB1,BEX4,SH3GL2,RPL28,CLMN,LAPTM4B,CDH2,TFCP2L1,BTC,DNM3,TMSB15A,C4A,RGS20,PKP2,ADD2,NRXN1,PLPP1,TLR3,DACT1,CNKSR3,MAGEA3,ZNF365,DOCK8,FZD1,GAPDH,FZD4,NKX3-2,WNT11,ASPH,FGFR1,IRS2,CXCL10,WFS1,PEMT,WWTR1,FARP1,C1QTNF3,ROBO2,CKAP2,PLAG1,FZD8,IPO5,UBAC2,GAS6,P2RY1,PKN1,EPHB1,ZNF219,PCBP4,BHLHA15,ZFP36L2,PARP9,TRPM4,VEGFC,BCL7A,RAPGEF2,RASA3,RACK1,PTPRC,TRIB3,ID3,NSD1,RPL12,AKT3,GNAO1,XBP1,NEK11,BMP4,SHOX2,ATP2B4,FOXA1,BTRC,TPT1,PHC1,TLL2,PHACTR3,FGF13,LMCD1,LILRB1,ASS1,NDRG2,HDGFL3,ITPR2,RPS6KA2,KCNAB1,TCAF2,EOMES,ITGB3,TLR4,ENO1,CD55,KCNIP3,ATF4,GCNT2,PNRC1,COL4A3,SPOCD1,PLEKHA1,TCERG1L,SESN1,TSKU,TRIM9,INSIG1,KLF12,ERN1,TNFRSF1A,CIART,DLX2,MLLT3,CHMP4C,RRAGD,PRKAA2,TYRO3,RGS16,RUNX2,STXBP5L,LGALS3,UBASH3B,RASL11B,SORBS3,ZIC2,PFN2,FHOD3,EFEMP1,ZBTB38,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,HS3ST5,LRP6,ADCY6,BNIP3,PAK1,FGFR4,MID2,EFNA3,GPSM1,STRADB,MAFB,PDE8A,MAPKAPK2,HEYL,SEMA3A,TESC,SIX2,SFN,PRKN,ID1,RBFOX2,NTRK3,TNKS1BP1,PPP1R9A,CBLN1,SEMA6A,CTNNA2,CYP26A1,RIDA,BCL6,ZNF488,SNAI2,GLI1,IGFBP3,RPS13,CTH,INTU,EVL,TMEM67,CSN2,NOP53,PRDM13,FGF12,RNF125,VIM,GSTO1,FRK,C4BPB,SMAD3,NRG3,PTPRJ,GBP1,PTPRS,HGF,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,NECAB2,BMPR2,GRB14,PAK5,APBB1,NLRP14,RASD1,USP30,ARHGAP44,FOXP2,MAP1A,RASD2,TFAP2A,KLF9,DUSP1,FOXN3,NUGGC,LITAF,NUAK2,PRICKLE1,MGMT,SMPDL3B,DKK1,DDAH1,FBN1,DLG2,RPL4,PAX9,TBC1D4,PTGES,PKIA,PPP4R4,ACVR1,LGR4,DUSP8,LDLR,VAMP8,GATA3,PRKCA,AARS,STK24,TRPS1,ZFYVE28,CHRDL1,PACSIN1,WISP3,NR6A1,ACVR1C,DEPTOR,BNIP3L,AGO4,ACVR2B,SAV1,GNAI1,AHRR,NCKAP1L,SH3RF1,PLK2,SERPINI1,SEMA3C,SPRY4,SPART,UNC5B,NRP1,SPOCK3,LZTS1,EFNB2,KLF8,INPPL1,ZHX3,GABRB2,MLF1,DHCR24,SLC25A27,OPHN1,TNFRSF10C,CHD5,GAS1,RPL13A,MECOM,IL17D,CNTN4,MYC,C1QL4,PRELID1,SREBF1,PRKG1,GPR161,BOD1,RNF152,PTCH2,EPB41L5,RPL26,QSOX1,VLDLR,PACSIN3,NSD2,PLCB1,PLEKHH2,PMEPA1,THBS4,SFMBT1,SMYD3,EPHA3,NBL1,PCSK1N,RASAL2,PLXNA2,MSR1,CHUK,TMEM170B,DDR1,TBC1D30,SPEG,ASNS,DAB2IP,PDE4D,SERPINH1,SHANK2,PREX1,NLGN4X,PRKCQ,CBY1,SATB2,ATF3,ATOH1,DCBLD2,SNCA,ISG20,BEX3,PRKCB,ASIC1,MAP3K21,HPGD,GRB10,KLF5,BMPR1A,ATG5,MID1,KCTD1,RPS20,MYO1D,MXI1,IGFBP6,EPS8,HERC5,ARL2,NDFIP2,RGS7,GDPD5,ADGRB2,NEDD4,HOPX,RGS17,AFF2,SGK3,PRKG2,FIG4,ERRFI1,YBX3,SMAD6,GFI1,SPRY2,SLC40A1,GSTM2,RPL21,CTTNBP2NL,GPLD1,CEBPB,TERT,PCGF2,MCC,LRRK1,CERS1,LARP1,DDIT3,B4GALT7,MVK,TNFAIP8L2,ABAT,IKZF2,KREMEN1,GSDME,EPCAM,TUBB4A,PPM1E,EPHB6,CTTN,FANK1,PTPRE,SLIT2,PDGFRB,PRKACB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,YAP1,ROR1,SERGEF,GSN,C8orf88,NCOA7,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,BCL11B,FN1,JDP2,FBXO4,STXBP6,CHADL,CHSY1,SPINK5,SATB1,DDIT4,ZNF354A,RPS11,BARX1,NOS3,ATP5IF1,GPR176,RHOQ,MSTN,WWC1,DUSP9,PRDM1,HERPUD1,RIPOR2,PLAGL1,ADGRB3,SH3BP4,HK2,PTPRN2,EGFL7,NKX2-8,IL15,COL18A1,HECW2,TDRKH,BCL6B,PIBF1,SCIN,SETDB2,CDC14B,FABP6,FHIT,PROS1,MET,WWC2,HSPA2,PRAME,PHLDB2,FER,PTPRU,TES,PTPN6,SYNJ2BP,DOCK5,WARS,BATF3,BCL11A,CAMK2N1,ZNF93,MSC,BACH2,RBPMS2,EIF4EBP1,DUSP19,RGS10,REL,LRP4,SSX1,IGF2BP2,SLX1B,NOTUM,OVOL2,CUEDC2,BMP6,RPL34,NKX6-1,RAB11FIP5,PRKCD,STC2,KIAA0319,IQGAP3,USP2,MSX1,KDM5B,CRIM1,NR4A1,PHACTR2,AGAP2,ZFPM2,TLR6,LEPR,CTIF,RERE,MAP1B,GPR37,MYADM,GCSAM,NACC2,MAP2K6,ACER2,CTSV,RPS12,GEM,MAP3K20,ABCG1 |
| 3.506e-04 | -7.96 | Sperma_CUB_dom_sf | interpro domains | IPR035914 | 52 | 14 | 18492 | 1811 |
ST14,BMP1,ATRNL1,C1R,PCOLCE2,SEZ6L2,NRP1,LRP3,ADGRG6,KREMEN1,LRP12,DCBLD1,DCBLD2,TLL2 |
| 3.520e-04 | -7.95 | positive regulation of stress fiber assembly | biological process | GO:0051496 | 47 | 13 | 17256 | 1658 |
PAK1,SMAD3,ARHGEF10L,PPM1E,EVL,PXN,GPR65,SORBS3,WNT11,SH3PXD2B,TPM1,NRP1,PFN2 |
| 3.520e-04 | -7.95 | regulation of chondrocyte differentiation | biological process | GO:0032330 | 47 | 13 | 17256 | 1658 |
EFEMP1,SMAD3,RUNX2,NKX3-2,CHADL,BMP4,ZNF219,SHOX2,BMP6,SIX2,SNAI2,TRPS1,SCIN |
| 3.536e-04 | -7.95 | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN | MSigDB lists | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN | 181 | 33 | 17377 | 1707 |
DMXL2,PDE1B,KLHL13,LPCAT2,CYP2J2,TNFSF13B,COL14A1,BBS9,LGI2,SLC30A4,MSMO1,TACC2,MARVELD2,ALDOC,LRP6,DAB2IP,IQGAP3,SMAD6,SYK,TBC1D8,B9D1,OPLAH,ANTXR2,GDPD1,DEPTOR,ZDHHC14,C3orf70,TBC1D16,GALNT3,PLXDC2,PELI2,RCN3,RNF122 |
| 3.536e-04 | -7.95 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_UP | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_UP | 181 | 33 | 17377 | 1707 |
CXCR5,UST,MPZL3,RUNX2,PRSS12,FBXO4,NSUN6,CYP4V2,RGS20,TTC30B,HOPX,RNF141,GPR15,SEMA4F,TRIM3,BEND4,TMEM37,ST8SIA1,IPCEF1,FZD4,PTPN13,SLC25A28,ATP11A,CRYBG3,HEG1,CAMK2N1,PKN3,FCHO2,BMPR1A,CMPK2,SUSD4,NRP1,FRMD5 |
| 3.538e-04 | -7.95 | epithelium development | biological process | GO:0060429 | 1060 | 135 | 17256 | 1658 |
EXPH5,ACVR1,LGR4,MCOLN3,ACTL8,GATA3,SKI,EPCAM,DLX6,MARVELD2,RAP2A,TBC1D32,POF1B,GSTM3,SLIT2,POU3F3,PRKACB,NKX2-1,SMAD9,KLHL3,YAP1,ACVR2B,SAV1,ARHGEF26,BDH2,SEMA3C,NRP1,TMEFF2,MAGI2,MEF2C,BCL11B,LGALS3,CELSR1,OPHN1,TJP1,SPINK5,TNFRSF19,PHGDH,SLC7A11,CA2,PDZD7,FRAS1,MYC,FLRT3,LRP6,BARX1,EPB41L5,PAK1,PTCH2,ENAM,DCHS1,RYR2,PRDM1,HEYL,CSF1,CECR2,WDR19,HOXD13,SEMA3A,CDH2,SIX2,SFN,TFCP2L1,ID1,ST14,PLXNA2,COL18A1,PKP2,NTRK3,DDR1,SETDB2,KAZN,ALDOC,DACT1,PDE4D,MET,SNAI2,PERP,FZD1,GLI1,INTU,NKX3-2,SOX21,WNT11,VIM,ATOH1,DSP,FGFR1,SMAD3,APELA,PTK7,ITGA2,PTPRS,KLF5,BMPR1A,COBL,HEY1,ROBO2,BMPR2,LRP4,OVOL2,BMP6,PPP2R3A,NKX6-1,DSG2,TFAP2A,ACTA2,PCK2,ERRFI1,SMAD6,SPRY2,PCSK6,B9D1,VEGFC,SLC40A1,MICAL2,MSX1,KDM5B,RAPGEF2,PRICKLE1,PALLD,FNDC3A,MGMT,DKK1,HEG1,CEBPB,ID3,MYADM,FAT4,EDA,XBP1,CTSV,BMP4,BTRC,FOXA1 |
| 3.547e-04 | -7.94 | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | MSigDB lists | REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION | 83 | 19 | 17377 | 1707 |
COL9A3,COL6A2,COL4A3,COL4A4,COL4A5,COL14A1,COL27A1,MMP15,COL22A1,PLOD2,ADAMTS3,COL25A1,BMP1,COL19A1,PCOLCE2,SERPINH1,MMP16,COL9A2,TLL2 |
| 3.555e-04 | -7.94 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_ACTIVITY | 64 | 16 | 17377 | 1707 |
EPHA3,FGFR4,TYRO3,CRIM1,EFNA3,NTRK3,ROR1,EPHB1,DDR1,FGFR1,EFEMP1,IGF1R,EPHB6,MET,NRP1,PDGFRB |
| 3.555e-04 | -7.94 | positive regulation of natural killer cell differentiation | biological process | GO:0032825 | 8 | 5 | 17256 | 1658 |
STAT5B,TOX,GAS6,IL15,RASGRP1 |
| 3.555e-04 | -7.94 | negative regulation of mitochondrial membrane potential | biological process | GO:0010917 | 8 | 5 | 17256 | 1658 |
BNIP3,PMAIP1,PRELID1,BNIP3L,SLC25A27 |
| 3.563e-04 | -7.94 | Activation of gene expression by SREBF (SREBP) | REACTOME pathways | R-HSA-2426168 | 42 | 12 | 10287 | 971 |
CYP51A1,IDI1,MVK,HMGCS1,MVD,SREBF1,FASN,SMARCD3,SQLE,SCD,DHCR7,HMGCR |
| 3.563e-04 | -7.94 | Netrin-1 signaling | REACTOME pathways | R-HSA-373752 | 42 | 12 | 10287 | 971 |
UNC5C,ABLIM1,DOCK1,MYO10,DCC,TRPC1,PRKCQ,AGAP2,UNC5B,TRPC3,SLIT2,NEO1 |
| 3.575e-04 | -7.94 | SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM | MSigDB lists | SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM | 35 | 11 | 17377 | 1707 |
ITGB7,MYC,PAM,P4HA1,TUFT1,SCD,PRDM1,CANX,TNFRSF17,AMPD1,ISG20 |
| 3.575e-04 | -7.94 | GO_CLATHRIN_MEDIATED_ENDOCYTOSIS | MSigDB lists | GO_CLATHRIN_MEDIATED_ENDOCYTOSIS | 35 | 11 | 17377 | 1707 |
SH3GL2,FCHO2,SYT12,OPHN1,HIP1,INPP5F,PACSIN1,CANX,FNBP1L,STON2,SNCA |
| 3.583e-04 | -7.93 | EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP | MSigDB lists | EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 196 | 35 | 17377 | 1707 |
ACSL1,IL32,RUSC2,ITGA6,CLSTN2,SCD,BCAN,FAM13A,BBS9,TPD52L1,FAM131B,EPB41L3,REEP1,ACTA2,NCAM1,AGL,PDLIM7,FER,MYO10,ATF7IP2,CALCRL,TNS1,PRKCQ,C1R,GPR37,CXCL10,AK1,GNAO1,WWTR1,AHNAK2,INPP4B,TPM1,MAPK10,AMPD1,MEF2C |
| 3.603e-04 | -7.93 | MODULE_179 | MSigDB lists | MODULE_179 | 417 | 63 | 17377 | 1707 |
MOCOS,SV2B,ACVR1,ACSL1,FN1,AASS,SLC25A27,BEGAIN,PRDM8,HBE1,IL13RA1,SCD,MAPK4,ISYNA1,IL18R1,CBLN1,BAG3,EPHB6,PDE4D,IPCEF1,TBC1D9,FAR2,LRP3,MED12L,SP140L,KDM5B,TBC1D8B,KLHL4,SOX21,SLC39A8,HOMER2,WDR25,SDC3,OBSCN,AGAP2,PRDM1,AMIGO1,TMEM47,SAV1,FGFR1,RERE,SMAD3,SPNS1,DEXI,GSN,CXCL10,ADAMTS3,CCBE1,CSF1,MAP2K6,ALDOA,WDR19,ABI3,NCOA7,PLEKHG1,DYNC2LI1,NXPH4,GEM,TNFSF4,LARP1,PKIA,RRAGD,SLC43A1 |
| 3.606e-04 | -7.93 | GO_CARDIAC_VENTRICLE_DEVELOPMENT | MSigDB lists | GO_CARDIAC_VENTRICLE_DEVELOPMENT | 103 | 22 | 17377 | 1707 |
SCN5A,TMEM65,GATA3,PKP2,RYR2,SMARCD3,WNT11,PRDM1,ZFPM2,SAV1,DSP,HEG1,TGFBR3,PTK7,HEYL,SEMA3C,TPM1,CPE,SMAD6,MEF2C,HEY1,FZD1 |
| 3.616e-04 | -7.92 | GTTRYCATRR_UNKNOWN | MSigDB lists | GTTRYCATRR_UNKNOWN | 152 | 29 | 17377 | 1707 |
DOC2A,PCSK1N,GAPDH,DCDC1,SLC37A1,TCTN2,ANK2,SPATA6,AGAP2,LRRC49,BATF,TBC1D16,TNKS1BP1,HPCAL4,TUBB4A,KCNK15,PPM1E,LRRC6,MPPED2,MPP2,GRIN2D,JAKMIP2,THAP10,CERS1,MAPK10,NKX2-8,ATP2B4,ATP1A3,PHC1 |
| 3.631e-04 | -7.92 | GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 58 | 15 | 17377 | 1707 |
CEBPB,PDLIM7,ACVR1,RUNX2,BMPR2,ZHX3,CD276,ACVR2A,CEBPA,HGF,ACVR2B,BMP4,BMPR1A,BMP6,MEF2C |
| 3.631e-04 | -7.92 | BROWNE_HCMV_INFECTION_1HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_1HR_UP | 58 | 15 | 17377 | 1707 |
HTR7,HLF,IGF1R,FUT9,KLHL23,CLGN,NR4A1,AFF2,PCBP4,LDLR,PRKCA,RASGRP1,ATP2B4,PCDH7,TLL2 |
| 3.631e-04 | -7.92 | GO_REGULATION_OF_CARTILAGE_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_CARTILAGE_DEVELOPMENT | 58 | 15 | 17377 | 1707 |
SMAD3,EFEMP1,RUNX2,BMPR2,NKX3-2,BMP1,CHADL,WNT11,BMP4,SHOX2,BMP6,SNAI2,SIX2,SCIN,TRPS1 |
| 3.640e-04 | -7.92 | REACTOME_SIGNALING_BY_HIPPO | MSigDB lists | REACTOME_SIGNALING_BY_HIPPO | 20 | 8 | 17377 | 1707 |
MOB1B,LATS2,AMOTL1,WWTR1,YAP1,WWC1,TJP1,SAV1 |
| 3.677e-04 | -7.91 | GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN | 174 | 32 | 17377 | 1707 |
CREB3L2,SERINC5,LATS2,MXI1,PPP4R4,SORBS1,PDE1B,ATP8A1,MLF1,GTF2IRD1,GATA3,LRRC49,TMEM170B,RBM11,DDIT4,PLS3,GALNT1,HMGCS1,ABCA5,AKAP7,TSC22D1,CNNM2,PCK2,RNF152,TRPM4,MOB1B,TDRD3,TMEM43,PDE8A,ARRDC4,CAMK2N1,CSF1 |
| 3.717e-04 | -7.90 | V$NKX61_01 | MSigDB lists | V$NKX61_01 | 219 | 38 | 17377 | 1707 |
TYRO3,CHCHD7,PTPRD,GABRB2,PLXNA2,GATA3,CREB5,SLC12A6,FAM81A,ARHGAP44,FOXP2,PPM1E,LHX6,SAMD11,BCL6,JAKMIP2,SLC6A15,HRK,MARCKS,FAR2,MYT1,RIMS2,RNF152,MYO10,ESRRG,PRDM13,FGF12,SATB2,ZFPM2,SKAP1,MBNL2,PLCB1,SMAD3,NSD1,MAP2,ZBTB20,PPARGC1A,MID1 |
| 3.722e-04 | -7.90 | PTPRK (protein tyrosine phosphatase, receptor type K) | protein interactions | 5796 | 114 | 24 | 17029 | 1718 |
TMEM67,COL6A2,B3GLCT,TCTN2,LGALS3,PTPRU,CNTNAP3,PLXNA2,AMIGO1,ARHGAP32,PEAK1,CLN5,CHST10,DCBLD2,RPL28,BCHE,ERO1B,FRAS1,LAMB1,MOXD1,GALNT18,CACNA2D1,CES3,PCSK5 |
| 3.722e-04 | -7.90 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | 273 | 45 | 17377 | 1707 |
MRC2,XYLT1,C1orf226,ASS1,COL4A5,ABAT,SLC19A2,NOS1AP,CHN1,BAG3,IGF1R,PMAIP1,MYC,MPPED2,SRGAP1,SGK3,ATRNL1,AFAP1L2,CPE,BOD1,CYP1B1,SUSD3,RHOQ,SLC27A2,SYBU,AK4,GSTO1,F12,SAV1,FRK,SMPDL3B,TSKU,IRS2,KCNMB4,PDLIM3,RPL28,GNB4,P4HA2,ITGA2,CCNA1,RAB31,HPGD,TTC39A,DHCR7,ATP2B4 |
| 3.750e-04 | -7.89 | Amino acid transport across the plasma membrane | REACTOME pathways | R-HSA-352230 | 31 | 10 | 10287 | 971 |
SLC7A1,SLC3A2,SLC7A11,SLC36A1,SLC7A5,SLC6A15,SLC7A2,SLC1A5,SLC16A10,SLC43A1 |
| 3.751e-04 | -7.89 | WEI_MIR34A_TARGETS | MSigDB lists | WEI_MIR34A_TARGETS | 138 | 27 | 17377 | 1707 |
BCL11B,RHOQ,ZNF395,LGR4,RECK,ZCCHC24,JPH1,HIP1,SLC7A2,CREB5,MGAT5B,PALLD,GLCE,NUMBL,HMGCS1,PLAGL1,RPL28,RALGPS2,PAM,MPP2,FIGN,MLLT3,MID1,CTNND2,PKIA,PDGFRB,HACE1 |
| 3.752e-04 | -7.89 | positive regulation of kinase activity | biological process | GO:0033674 | 589 | 82 | 17256 | 1658 |
EPHA3,NEK10,ACSL1,AVPI1,FGF13,NTRK3,LCP2,SNX9,PIBF1,DDR1,PPP1R9A,STK24,TLR3,ITGB3,DAB2IP,EPHB6,MET,TLR4,PRKACB,RASGRP1,PDGFRB,FZD4,PFKFB2,TGFA,LRRK2,ADCY1,WNT11,PRKAR2B,ACVR2B,ROR1,CD40,FGFR1,SNCA,NRG3,GPRC5B,NCKAP1L,ERN1,MAP3K21,DUSP19,TNFSF15,HGF,DIRAS1,MAPK10,CACUL1,TENM1,TYRO3,TNIK,PAK5,FZD8,SLK,GAS6,PKN1,EPHB1,TPD52L1,IGF1R,PRKCD,GHR,ADCY6,INAVA,AFAP1L2,IQGAP3,TNFRSF11A,SYK,SPRY2,PAK1,FGFR4,VAV3,RAPGEF2,VLDLR,STRADB,DUSP9,AGAP2,TLR6,DKK1,PTPRC,MAPKAPK2,FGR,CSF1,MAP2K6,BMP4,MAP3K20,ATP2B4 |
| 3.752e-04 | -7.89 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | 189 | 34 | 17377 | 1707 |
EXPH5,TRIM2,BMPR2,FGF13,PLEKHA5,ITGA6,ADAMTS6,FSTL5,TXNRD3,EPCAM,MCOLN2,TACC2,MARVELD2,SGK1,MED7,IPCEF1,GFI1,FANK1,NEB,VAV3,GPR176,PFKFB2,TMTC4,SHISA2,ST6GALNAC3,ARHGAP32,GUCY1A2,MFSD6,C1orf174,CCNA1,HPGD,BMP4,NRP1,HS6ST3 |
| 3.752e-04 | -7.89 | GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN | MSigDB lists | GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN | 189 | 34 | 17377 | 1707 |
TRIM2,CFH,ST14,BACE1,IPO5,GATA3,NTRK3,BCAN,LCP2,IKZF2,PHLDA2,EYA4,SLC16A2,STARD4,PROS1,C3orf67,RPL26,VNN2,LCA5,DCC,DUSP9,SAV1,GPRC5B,MAP2,PELI2,OSBPL5,NCOA7,ZBTB20,NRP1,NEUROG2,DHCR7,TTC39A,IL9R,NUDT17 |
| 3.752e-04 | -7.89 | GSE29618_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DN | 189 | 34 | 17377 | 1707 |
SERINC5,ACSL1,BLVRB,VAMP8,CEBPA,CREB5,SFXN3,SLCO3A1,RTN1,EPB41L3,MGAT1,TLR4,ENO1,CEBPD,GAB2,FZD1,PAK1,RIN2,QSOX1,PXN,MPP1,MAFB,SMARCD3,GSTO1,VIM,COTL1,WARS,HPSE,RAB31,KIAA0513,SVIL,RNF130,STOM,PCSK5 |
| 3.752e-04 | -7.89 | GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN | MSigDB lists | GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN | 189 | 34 | 17377 | 1707 |
CREB3L2,SCAMP1,CYP2J2,PTPN21,IGF2BP2,GPSM2,NUDT12,SLC19A2,EYA4,F3,PPM1E,HMGCS1,ZNF438,GRHL1,SCN1B,CACNB2,STARD4,RAP2A,PDE4D,NIPAL2,PRR16,HSPA2,SLIT2,RBMS2,SLC39A8,CPEB1,IFT81,LMLN,DOCK7,INSIG1,PLEKHG1,DSEL,CSRP2,STOM |
| 3.752e-04 | -7.89 | GO_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | MSigDB lists | GO_REGULATION_OF_MUSCLE_SYSTEM_PROCESS | 189 | 34 | 17377 | 1707 |
SCN5A,LMCD1,GTF2IRD1,PKP2,ABAT,PRKCA,NEDD4,NOS1AP,FBXO32,DSG2,PRKG1,CTTN,PDE4D,ERRFI1,KCNB2,CHRM3,NOS3,TRPM4,GSTM2,MSTN,ANK2,CALCRL,RYR2,GSTO1,ATP1B1,ASPH,DSP,DOCK5,ITGA2,OXTR,TPM1,PPARGC1A,TRPC3,ATP2B4 |
| 3.752e-04 | -7.89 | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_IL7_VS_IL4_MEMORY_CD8_TCELL_UP | 189 | 34 | 17377 | 1707 |
LRFN5,ANKRD13D,TRIM2,ITPRIP,RECK,MCTP2,NDRG2,RNF24,KIF21B,SLC19A2,PGAP1,TXNRD3,OTUD1,GRHL1,PCBP4,MARCH3,BEND4,IPCEF1,ZFP36L2,SLC45A3,PRKACB,KDM5B,TMEM65,SPATA13,CCNG1,CRYBG3,GPR19,HEG1,ZFP62,INHBC,FCHO2,PGM2L1,NRP1,PURG |
| 3.752e-04 | -7.89 | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP | MSigDB lists | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP | 189 | 34 | 17377 | 1707 |
CXCR5,CREB3L2,ARHGAP26,PDE1B,ITGA6,MCTP2,PSD3,KCTD12,TECPR1,FRY,EHD3,DENND1C,TLR4,RAPGEF5,RASGRP1,PRKACB,PAK1,SLC40A1,BCL7A,UROS,CRIM1,RAPGEF4,SPATA13,NUAK2,STRADB,CR2,VIM,CD40,RERE,PTPRC,NCKAP1L,IL9R,SFN,LPP |
| 3.754e-04 | -7.89 | human chr5q35.1 | chromosome location | human chr5q35.1 | 38 | 10 | 26185 | 1967 |
BNIP1,ERGIC1,LOC100268168,NPM1,SH3PXD2B,LCP2,RPL26L1,DOCK2,UBTD2,DUSP1 |
| 3.803e-04 | -7.87 | KUMAR_TARGETS_OF_MLL_AF9_FUSION | MSigDB lists | KUMAR_TARGETS_OF_MLL_AF9_FUSION | 377 | 58 | 17377 | 1707 |
CXCR5,PLA2G4A,MOCOS,MYO1D,SEMA6B,GNG12,TTC39B,RECK,DNAJC3,ST6GAL1,UGDH,GATA3,SCD,PRKCA,DDR1,TNFRSF19,SATB1,PLS3,MCOLN2,FKBP9,ZNF362,ABLIM1,NAV1,HMGCS1,EOMES,RALGPS2,SLC30A4,HPS1,COL19A1,DAB2IP,TSPAN13,MARCKS,PTPRCAP,PERP,CD55,GAPDH,PDK1,SPATA6,FASN,SPATA13,DUSP9,C1R,GSTO1,PRKCQ,LHPP,ATP1B1,ZDHHC14,DSP,GALNT3,EBF1,ICA1,TERT,GNB4,RAB31,HK2,HPGD,CMPK2,MEF2C |
| 3.812e-04 | -7.87 | GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | MSigDB lists | GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | 167 | 31 | 17377 | 1707 |
ARHGAP26,VAV3,ARAP2,ACSL1,ALOX5AP,ST6GAL1,RAPGEF4,GATA3,SELL,FAM102B,PRKCQ,ADSSL1,TEX9,SLCO3A1,IL18R1,GSN,PPM1E,IQCH,CDC14B,KMO,GPR155,AKT3,P4HA2,KCNG1,RGS10,BBC3,FAM84B,ST8SIA1,GFRA1,AMPD1,SLC16A10 |
| 3.827e-04 | -7.87 | V$OCT1_Q5_01 | MSigDB lists | V$OCT1_Q5_01 | 250 | 42 | 17377 | 1707 |
TCP11L2,ITPRIP,REL,CADM2,MGAT5B,NRXN1,FOXG1,HPCAL4,PPP2R3A,FSTL5,MTUS1,FOXP2,GALNT1,ZNF362,LRRN1,COL25A1,LHX6,RAB26,MPPED2,PRICKLE2,SLC6A15,TSPAN13,PPP2R2B,PDE4D,ETV1,SEMA6C,GAB2,BDNF,GPM6A,FZD4,STAT4,FGF12,NFIA,PRDM1,TCERG1L,EBF1,GPRC5B,MAP2K6,TMOD2,DLG2,MID1,TLL2 |
| 3.833e-04 | -7.87 | positive regulation of transport | biological process | GO:0051050 | 908 | 118 | 17256 | 1658 |
EXPH5,PRKN,DNM3,SORBS1,TRIM16,C4A,ATP8A1,LDLR,VAMP8,PKP2,GATA3,CHUK,ABAT,DOCK2,NCS1,NOS1AP,SCIN,BAG3,UNC13B,SEC16B,TCAF2,PMAIP1,KMO,CNKSR3,TRPC1,SYNGR3,RAB27B,MYRIP,TLR4,PLTP,HSPA2,IL1RAP,RASGRP1,PDGFRB,ALG10B,GAB2,GAPDH,PFKFB2,WLS,ANK2,LRRK2,FGF12,FEZ1,GSTO1,ATP1B1,AMIGO1,RARRES2,SGK2,FGFR1,SNCA,IRS2,SMAD3,CXCL10,NCKAP1L,WFS1,APELA,ITGA2,BBC3,OXTR,ATG5,TNFSF4,MAGI2,CNTN1,TENM1,SCN5A,LGALS3,STXBP5L,C1QTNF3,APBB1,IPO5,GAS6,P2RY1,MLC1,BMP6,NEDD4,MCU,NKX6-1,LRRC55,CA2,SCN1B,GATA2,CACNB2,PRKCD,EHD3,PRELID1,SGK3,SGK1,LMAN2,CADPS2,PCK2,STXBP1,TNFRSF11A,SYK,PAK1,TRPM4,VEGFC,ATP5IF1,GSTM2,RAB3B,RHOQ,SYBU,RYR2,HIP1,RACK1,LRAT,ZIC1,GPLD1,FGR,TERT,MAP2K6,XBP1,TRPC3,CDH2,TESC,SFN,CACNA2D1,ABCG1,STOM |
| 3.846e-04 | -7.86 | GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_SMALL_MOLECULE_BIOSYNTHETIC_PROCESS | 418 | 63 | 17377 | 1707 |
UST,PLA2G4A,PRKAA2,GPT2,MVK,ELOVL4,ALOX5AP,ENO2,LPCAT2,ELOVL7,UGDH,OLAH,DHCR24,ASS1,CBS,SCD,ISYNA1,ABAT,SLC1A3,LPIN3,BCAN,PHGDH,CDS1,CYP51A1,IDI1,HMGCS1,ASNS,MSMO1,KMO,ALDOC,PCK2,PLTP,ENO1,GATM,SYK,CTH,HMGCR,FADS1,GAPDH,ATF4,PNP,UROS,SLC27A2,CYB5R2,MVD,ELOVL3,FASN,ATF3,GSTO1,PYCR1,INSIG1,ACER2,PEMT,ALDOA,XBP1,BDH2,SQLE,DSEL,PPARGC1A,DHCR7,PTGES,PSPH,ACSM3 |
| 3.878e-04 | -7.85 | cardiac muscle cell action potential involved in contraction | biological process | GO:0086002 | 36 | 11 | 17256 | 1658 |
SCN5A,KCNN2,SCN1B,CACNB2,ANK2,FGF12,RYR2,PKP2,KCND3,CACNA2D1,GJC1 |
| 3.879e-04 | -7.85 | VALK_AML_CLUSTER_10 | MSigDB lists | VALK_AML_CLUSTER_10 | 30 | 10 | 17377 | 1707 |
MN1,BCL7A,CRIM1,CHRDL1,SETBP1,PIK3C2B,SORBS3,NPDC1,MLLT3,GNAI1 |
| 3.879e-04 | -7.85 | GO_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | 30 | 10 | 17377 | 1707 |
CHSY3,GALNT3,GBGT1,GALNT1,GALNT12,GALNT6,GALNT13,CHSY1,B4GALNT3,GALNT14 |
| 3.879e-04 | -7.85 | GGTAACC,MIR-409-5P | MSigDB lists | GGTAACC,MIR-409-5P | 30 | 10 | 17377 | 1707 |
TRIM9,GNG12,GPM6A,KLF12,SCAMP1,ACVR2A,KIF1B,PURG,TRPS1,ZIC1 |
| 3.910e-04 | -7.85 | amino acid import | biological process | GO:0043090 | 16 | 7 | 17256 | 1658 |
SLC7A1,SLC36A4,SLC3A2,SLC7A2,SLC1A3,SLC1A5,SH3BP4 |
| 3.920e-04 | -7.84 | GO_NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | 518 | 75 | 17377 | 1707 |
PPP4R4,DUSP8,AKAP5,DNAJC3,NPM1,NDRG2,CEBPA,NTRK3,PRKCA,PIBF1,PPM1E,PPP1R26,ZFYVE28,CNKSR3,DACT1,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,SPOCD1,PTPN6,LRRK2,DEPTOR,PRKAR2B,ATF3,SYNJ2BP,SNCA,SMAD3,IRS2,CAMK2N1,RANBP2,ENPP1,PTPRJ,NCKAP1L,GBP1,WWTR1,DUSP19,GRB10,INPP5F,HGF,SPRY4,PPARGC1A,MYO1D,LATS2,FARP1,UBASH3B,PKN1,MECOM,DDIT4,IGF1R,MYC,FLRT3,C1QL4,PRKCD,LRP6,ERRFI1,SMAD6,SPRY2,DUSP1,HMGCR,MSTN,DUSP9,DKK1,PTPRC,TRIB3,MYADM,PMEPA1,DLG2,BMP4,LRRK1,SMYD3,TESC,PKIA,SFN |
| 3.920e-04 | -7.84 | GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 518 | 75 | 17377 | 1707 |
PPP4R4,DUSP8,AKAP5,DNAJC3,NPM1,NDRG2,NTRK3,CEBPA,PRKCA,PIBF1,PPM1E,PPP1R26,ZFYVE28,CNKSR3,DACT1,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,SPOCD1,PTPN6,LRRK2,DEPTOR,PRKAR2B,ATF3,SYNJ2BP,SNCA,SMAD3,IRS2,CAMK2N1,RANBP2,ENPP1,PTPRJ,NCKAP1L,GBP1,WWTR1,DUSP19,GRB10,HGF,INPP5F,SPRY4,PPARGC1A,MYO1D,LATS2,FARP1,UBASH3B,PKN1,DDIT4,MECOM,IGF1R,FLRT3,MYC,C1QL4,PRKCD,LRP6,ERRFI1,SMAD6,SPRY2,DUSP1,HMGCR,MSTN,DUSP9,DKK1,PTPRC,TRIB3,MYADM,PMEPA1,DLG2,LRRK1,BMP4,SMYD3,TESC,PKIA,SFN |
| 3.920e-04 | -7.84 | GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP | MSigDB lists | GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP | 182 | 33 | 17377 | 1707 |
GNG12,ALOX5AP,RNF144A,RUSC2,RGS7,SNX9,SLC19A2,KREMEN1,DDX60L,STK24,NEDD4,TRPS1,EIF1,STARD4,JAKMIP2,CTTN,ERRFI1,MET,FMNL2,CKAP4,ATP2B1,CARD6,CD55,PNP,PDK1,WLS,BNIP3L,RIMKLB,PELI2,GPR160,NCOA7,HK2,CAB39L |
| 3.920e-04 | -7.84 | GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN | MSigDB lists | GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN | 182 | 33 | 17377 | 1707 |
PLA2G4A,INPPL1,ACSL1,SIDT1,ST14,LSM11,MCTP2,SLC36A4,LACC1,PHGDH,ADSSL1,FKBP11,IGF1R,BCL6,NAP1L3,STEAP3,FAM84B,SNX10,PTPRE,B9D1,ABCC4,PRKCQ,PLEKHA1,SPATA7,ENTPD1,LMLN,TMEM154,KPNA3,TERT,OSBPL5,SVIL,SLCO5A1,DIRC2 |
| 3.920e-04 | -7.84 | GSE2706_UNSTIM_VS_8H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_R848_DC_DN | 182 | 33 | 17377 | 1707 |
IL15,REL,COBLL1,PSD3,HERC5,HERC6,DDX60L,SLC9A7,MCOLN2,GRHL1,PMAIP1,AFAP1L2,ARL4D,MOXD1,RASGRP1,KIAA1211,IGSF3,PARP9,STAT4,RAPGEF2,FEZ1,YAP1,BATF,ISG20,WARS,CXCL10,INSIG1,PLAGL1,GBP1,TNFSF15,CMPK2,SLFN5,RAB30 |
| 3.920e-04 | -7.84 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN | 182 | 33 | 17377 | 1707 |
RGS16,TNFSF13B,TJP1,ABHD4,SNX9,BAG3,TGFBR3,PIK3AP1,ST8SIA1,GFI1,QSOX1,SLC3A2,HIP1,ATF3,FNDC3A,BAIAP2,HERPUD1,GABARAPL1,ISG20,ENTPD1,CXCL10,PTPRJ,PMEPA1,ERN1,XBP1,RGS10,INPP4B,SLC7A5,SQLE,INPP5F,SLC16A10,ATP2B4,DOCK9 |
| 3.922e-04 | -7.84 | positive regulation of gamma-delta T cell activation | biological process | GO:0046645 | 5 | 4 | 17256 | 1658 |
LILRB1,STAT5B,NCKAP1L,SYK |
| 3.922e-04 | -7.84 | Purkinje myocyte to ventricular cardiac muscle cell signaling | biological process | GO:0086029 | 5 | 4 | 17256 | 1658 |
TRPM4,RYR2,SCN5A,SCN1B |
| 3.954e-04 | -7.84 | Glycine and Serine Metabolism | SMPDB pathways | SMP00004 | 26 | 10 | 992 | 118 |
GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.954e-04 | -7.84 | Dihydropyrimidine Dehydrogenase Deficiency (DHPD) | SMPDB pathways | SMP00179 | 26 | 10 | 992 | 118 |
GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.954e-04 | -7.84 | Non Ketotic Hyperglycinemia | SMPDB pathways | SMP00223 | 26 | 10 | 992 | 118 |
GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.954e-04 | -7.84 | Dimethylglycine Dehydrogenase Deficiency | SMPDB pathways | SMP00484 | 26 | 10 | 992 | 118 |
GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.954e-04 | -7.84 | Sarcosinemia | SMPDB pathways | SMP00244 | 26 | 10 | 992 | 118 |
GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.954e-04 | -7.84 | 3-Phosphoglycerate dehydrogenase deficiency | SMPDB pathways | SMP00721 | 26 | 10 | 992 | 118 |
GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.954e-04 | -7.84 | Hyperglycinemia- non-ketotic | SMPDB pathways | SMP00485 | 26 | 10 | 992 | 118 |
GARS,ALDH2,GCAT,CBS,MAOA,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.954e-04 | -7.84 | Dimethylglycine Dehydrogenase Deficiency | SMPDB pathways | SMP00242 | 26 | 10 | 992 | 118 |
GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.956e-04 | -7.84 | GNF2_AF1Q | MSigDB lists | GNF2_AF1Q | 25 | 9 | 17377 | 1707 |
RTN1,GPM6A,PTPRD,ATP9A,GNAO1,ANK2,ADCY1,KIF5C,DYNC1I1 |
| 4.004e-04 | -7.82 | leading edge membrane | cellular component | GO:0031256 | 166 | 30 | 18223 | 1724 |
EPB41L5,PAK1,MYO1D,ATF4,ROBO2,WLS,EPS8,SPATA13,GABRG2,FERMT2,WWC1,PSD3,PLEKHA1,KCNC4,ARHGAP44,GABARAPL1,EPB41L3,FGR,PTPRJ,RIPOR2,ITGB3,MPP2,SPRY4,PACSIN1,MYO6,TPM1,SPRY2,TESC,DOCK8,ATP2B1 |
| 4.005e-04 | -7.82 | testis-germ_cell_tumour-seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-seminoma | 658 | 91 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,PLXNA2,RHPN2,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,TRPS1,RTN1,BAG3,SPEG,PPM1E,RPS6KA2,COL25A1,RPS6KL1,MYO3B,ACVR2A,MET,NEB,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,ANK2,LRRK2,ZNF565,PRKCQ,PRKAR2B,ROR1,ACVR2B,SGK2,TBC1D16,FRK,FGFR1,ZNF569,DYRK1B,PRKCB,PLK2,PTK7,ERN1,BMP1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PKN1,EPHB1,IGF1R,ADCK1,PDE10A,PRKCD,SGK3,PRKG1,RALGAPA2,SGK1,ALPK1,SYK,FES,MED12L,PAK1,FGFR4,PTPN13,NUAK2,OBSCN,STRADB,CDC42BPA,MAPKAPK2,KCNK15,TRIB3,FGR,PKN3,PRCP,AKT3,MAP2K6,SRD5A3,MCC,CDH17,NEK11,KIF1B |
| 4.011e-04 | -7.82 | seminoma | COSMIC cancer mutations | seminoma | 710 | 97 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,PLXNA2,RHPN2,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,TRPS1,RTN1,BAG3,SPEG,PPM1E,RPS6KA2,COL25A1,RPS6KL1,MYO3B,ACVR2A,MET,NEB,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,ANK2,LRRK2,ZNF565,PRKCQ,PRKAR2B,ROR1,ACVR2B,SGK2,TBC1D16,FRK,FGFR1,ZNF569,DYRK1B,PRKCB,PLK2,PTK7,ERN1,BMP1,MAPK13,BMPR1A,SPRY4,CNTN1,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PKN1,EPHB1,KCNC4,IGF1R,ADCK1,PDE10A,PRKCD,SGK3,PRKG1,RALGAPA2,PRICKLE2,SGK1,ALPK1,SYK,FES,MED12L,PAK1,FGFR4,PTPN13,NUAK2,OBSCN,STRADB,CDC42BPA,MAPKAPK2,KCNK15,TRIB3,FGR,FAT4,TERT,PKN3,PRCP,AKT3,MAP2K6,SRD5A3,MCC,CDH17,NEK11,KIF1B |
| 4.016e-04 | -7.82 | positive regulation of neuron projection development | biological process | GO:0010976 | 256 | 42 | 17256 | 1658 |
EPHA3,PRKN,FN1,ROBO2,BMPR2,PTPRD,APBB1,PLXNA2,NTRK3,PPP1R9A,RND2,SCN1B,GRIP1,DAB2IP,FIG4,PACSIN1,SLIT2,IL1RAP,RIMS2,FES,FZD1,PAK1,BDNF,FZD4,RAPGEF2,VLDLR,SHANK2,FEZ1,AMIGO1,BAIAP2,FGFR1,MAP1B,NEGR1,PTK7,SERPINI1,HGF,NRP1,MAGI2,SHOX2,COBL,SHTN1,CNTN1 |
| 4.035e-04 | -7.82 | GO_CELL_SUBSTRATE_JUNCTION | MSigDB lists | GO_CELL_SUBSTRATE_JUNCTION | 386 | 59 | 17377 | 1707 |
ARHGAP26,EFNB2,MRC2,SORBS1,ITGA6,ARHGAP22,NPM1,ENAH,SORBS3,RPL13A,FLRT3,RPS11,PPFIBP1,EHD3,ITGB3,SCARF2,MARCKS,CTTN,TLN2,RRAS2,TSPAN9,PDGFRB,FES,RPS13,FZD1,PDLIM7,PAK1,EPB41L5,PHLDB2,SYNPO2,PXN,EVL,TES,CAPN5,ASAP3,FHL2,FERMT2,VIM,TNS1,PALLD,SNTB1,PEAK1,PTPRC,GSN,RPL12,DOCK7,LMLN,RND3,PTK7,FAT1,ITGA2,SVIL,SPRY4,RPL4,NRP1,CDH2,CSRP2,MME,LPP |
| 4.066e-04 | -7.81 | Signaling by Hippo | REACTOME pathways | R-HSA-2028269 | 21 | 8 | 10287 | 971 |
YAP1,WWC1,MOB1B,LATS2,TJP1,AMOTL1,SAV1,WWTR1 |
| 4.066e-04 | -7.81 | CUB | smart domains | SM00042 | 47 | 14 | 9493 | 1056 |
ST14,BMP1,ATRNL1,C1R,PCOLCE2,NRP1,SEZ6L2,ADGRG6,KREMEN1,LRP3,DCBLD1,LRP12,TLL2,DCBLD2 |
| 4.082e-04 | -7.80 | GO_CEREBRAL_CORTEX_CELL_MIGRATION | MSigDB lists | GO_CEREBRAL_CORTEX_CELL_MIGRATION | 41 | 12 | 17377 | 1707 |
DISC1,FGF13,LHX6,LAMB1,DAB2IP,EFHC1,NRP1,SEMA3A,SLIT2,POU3F3,FGFR1,NKX2-1 |
| 4.082e-04 | -7.80 | REACTOME_PLC_BETA_MEDIATED_EVENTS | MSigDB lists | REACTOME_PLC_BETA_MEDIATED_EVENTS | 41 | 12 | 17377 | 1707 |
PLA2G4A,PDE1B,GNAO1,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PRKCA,PLCB1,PRKACB,GNAI1 |
| 4.082e-04 | -7.80 | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | MSigDB lists | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | 41 | 12 | 17377 | 1707 |
SYNPO2,PMEPA1,CRIM1,DSTN,PAM,DSEL,TNS1,TPM1,TPD52L1,JAM3,CSRP2,MAP1B |
| 4.100e-04 | -7.80 | - | gene3d domains | 2.60.120.290 | 49 | 14 | 8148 | 867 |
ST14,BMP1,ATRNL1,C1R,PCOLCE2,SEZ6L2,NRP1,LRP3,ADGRG6,KREMEN1,LRP12,DCBLD1,DCBLD2,TLL2 |
| 4.148e-04 | -7.79 | GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 190 | 34 | 17377 | 1707 |
COL9A3,MVK,MXI1,RECK,UBAC2,COL18A1,IGF2BP2,ZIC2,IKZF2,TPD52L1,SNX9,TTC30B,DDIT4,F3,PLS3,SIPA1L2,SOAT2,SLC22A17,PCBP4,BCL6,PTPRCAP,ZFP36L2,DUSP1,B4GALT6,EVL,RNF145,WLS,CR2,MMP15,MATN2,WWTR1,HK2,HPGD,MME |
| 4.151e-04 | -7.79 | ovary-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-clear_cell_carcinoma | 676 | 93 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,TCP11L2,CELSR3,GATA3,NDRG2,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,COL22A1,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,IL1RAP,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,NR6A1,LRRK2,NLGN4X,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,BCL11A,DYRK1B,SMAD3,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,PLD5,LIFR,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,ZHX3,PKN1,EPHB1,CHD5,IGF1R,ADCK1,PDZD7,PRKCD,SGK3,PRKG1,TFAP2A,SGK1,ALPK1,SYK,FES,PAK1,FGFR4,PCDH10,SLITRK2,MCF2L2,NUAK2,OBSCN,STRADB,PLS1,CDC42BPA,B4GALNT3,MAPKAPK2,TRIB3,FGR,PCDHB7,FAT4,TERT,PKN3,AKT3,MAP2K6,NEK11,FILIP1,AMPD1 |
| 4.168e-04 | -7.78 | GO_PALATE_DEVELOPMENT | MSigDB lists | GO_PALATE_DEVELOPMENT | 84 | 19 | 17377 | 1707 |
MSX1,ARID5B,SATB2,WNT11,ACVR2B,PLEKHA1,ASPH,SKI,MSC,TGFBR3,INSIG1,DLX6,FRAS1,TFAP2A,LRP6,BMPR1A,SNAI2,MEF2C,FZD1 |
| 4.169e-04 | -7.78 | V$NFAT_Q4_01 | MSigDB lists | V$NFAT_Q4_01 | 251 | 42 | 17377 | 1707 |
AMOTL1,PPP4R4,SCAMP1,VAMP8,NDRG2,SORBS3,CADM2,MAPK4,NOTUM,ISYNA1,CREB5,OVOL2,PRRG4,PPP2R3A,TRPS1,RND2,FOXP2,EOMES,STC2,CHRDL1,ST8SIA1,GFI1,ETV1,IGFBP3,PCDH10,USP2,KLHL4,PRDM1,SNAP25,MBNL2,EBF1,GSN,ID3,SH3RF1,PLOD2,ABI3,KLF5,SHOX2,SEMA3A,NR3C2,PTGES,HS6ST3 |
| 4.175e-04 | -7.78 | Rho GTPase binding | molecular function | GO:0017048 | 169 | 31 | 17224 | 1680 |
PAK1,VAV3,FARP1,ARHGEF28,ARHGEF11,DOCK1,PAK5,MCF2L2,STXBP6,LRRK2,EPS8,PREX1,SPATA13,OBSCN,PKN1,DOCK2,ARHGAP44,TIAM2,ARHGEF26,ARHGEF10L,DOCK7,PKN3,RASGRF2,MCF2L,PLEKHG1,SRGAP1,RTKN2,IQGAP3,YBX3,FMNL2,HACE1 |
| 4.185e-04 | -7.78 | DOCK_N | pfam domains | PF16172 | 5 | 4 | 17054 | 1666 |
DOCK3,DOCK5,DOCK1,DOCK2 |
| 4.213e-04 | -7.77 | TAGCTTT,MIR-9 | MSigDB lists | TAGCTTT,MIR-9 | 228 | 39 | 17377 | 1707 |
BCL11B,PCDH18,LRP4,RIMKLA,ENAH,ZIC2,CREB5,KIAA1217,ZNF362,CNTN4,KCNN2,FRAS1,MAP7,FAM84B,LRP12,EPB41L5,GPM6A,PDK1,SKAP2,SLITRK2,KLHL3,SOX21,CYTH3,DNAJC6,ATP11A,TMEM47,ZFPM2,NEGR1,NAP1L5,BACH2,AKT3,C1orf21,SFMBT1,TPM1,MMP16,CRISPLD1,CTNND2,TLL2,MEF2C |
| 4.227e-04 | -7.77 | DOCK_N | interpro domains | IPR032376 | 5 | 4 | 18492 | 1811 |
DOCK3,DOCK5,DOCK1,DOCK2 |
| 4.250e-04 | -7.76 | MODULE_163 | MSigDB lists | MODULE_163 | 511 | 74 | 17377 | 1707 |
DMXL2,BTC,CELSR3,DOCK1,GRIK2,VAMP8,MCOLN3,TDRKH,NTRK3,SEZ6L2,NRXN1,DENND3,CACNB4,TXNDC5,ADPRHL1,SIPA1L2,TYMP,PPFIA2,POF1B,SNX10,ZNF365,PERP,SEMA6C,PRKACB,SKAP2,KLHL3,TTC22,SLC25A28,SERGEF,ATP10D,TPK1,GSN,AK1,SH3RF1,EIF4EBP1,NRP1,SUSD4,COBL,PURG,UST,KCNV1,ANO10,RGS16,SEMA6B,GRB14,OPHN1,GALNT13,P2RY1,INPP1,DDIT4,KCNJ4,MAP1A,MCF2L,DSG2,STC2,KIAA0319,KCNMB3,STXBP1,TBC1D8B,COL4A4,ASAP3,SLITRK5,TAF4B,PALLD,TERT,ZNF214,PELI2,CECR2,PLXDC2,FMO4,NXPH4,THAP10,XKR4,TLL2 |
| 4.254e-04 | -7.76 | regulation of sterol biosynthetic process | biological process | GO:0106118 | 42 | 12 | 17256 | 1658 |
CYP51A1,IDI1,MVK,HMGCS1,MVD,SREBF1,FASN,SQLE,SCD,DHCR7,ABCG1,HMGCR |
| 4.254e-04 | -7.76 | cholesterol biosynthetic process | biological process | GO:0006695 | 42 | 12 | 17256 | 1658 |
PRKAA2,CYP51A1,IDI1,MVK,HMGCS1,INSIG1,MSMO1,MVD,DHCR24,SQLE,DHCR7,HMGCR |
| 4.254e-04 | -7.76 | regulation of cholesterol biosynthetic process | biological process | GO:0045540 | 42 | 12 | 17256 | 1658 |
CYP51A1,IDI1,MVK,HMGCS1,MVD,SREBF1,FASN,SQLE,SCD,DHCR7,ABCG1,HMGCR |
| 4.276e-04 | -7.76 | protein localization | biological process | GO:0008104 | 1943 | 229 | 17256 | 1658 |
EXPH5,THOC5,CACNG3,UGT8,FGF13,GRIK2,KIF5A,VAMP8,LILRB1,GATA3,NPM1,SNX9,NUP62CL,TRPS1,ADPRHL1,SEC16B,PMAIP1,AKAP7,RAP2A,RAB26,NDUFB8,TBC1D32,LIN7A,TMED9,CTTN,COG3,TLN2,PACSIN1,MYRIP,TLR4,CPE,IL1RAP,TBC1D8,DBN1,GDAP1,ITGB7,KCNIP3,WLS,ANK2,EXOC6B,LRRK2,ACVR2B,PLEKHA1,ZDHHC14,GSN,INSIG1,TNFRSF1A,NRP1,APBA2,MAGI2,RRAGD,PCSK5,CHMP4C,STXBP5L,CELSR1,HID1,SEC24D,TBC1D1,STXBP6,DHCR24,ATP6V1E2,APBA1,MLC1,BBS9,PGAP1,RPL13A,GRPEL2,SPIRE1,MCOLN2,PDZD7,FRAS1,CACNB2,RPS11,LRP6,GRIP1,LMAN2,CADPS2,STXBP1,RPS23,RIMS2,SNX7,BOD1,RPL26,MID2,PNP,TBC1D8B,PLEKHA8,VLDLR,RAPGEF4,DCHS1,RYR2,HIP1,STRADB,OBSCN,CALCRL,PEX5L,SNAP25,ARRDC4,HERPUD1,SPATA7,BAIAP2,TBC1D2,VPS37D,RPL28,FCHO2,WDR19,SH3BP4,RAB31,HK2,PTPRN2,CDH2,SMYD3,TESC,SIX2,PRKN,NBL1,ID1,SCAMP1,AKAP5,TMSB15A,RHOD,MSR1,PKP2,CANX,LCP2,NRXN1,PIBF1,PCLO,TBC1D30,CBLN1,ZFYVE9,SCIN,CCDC120,EPB41L3,REEP1,ZDHHC6,BCL6,ZDHHC23,MAP7,NBEA,RTKN2,STEAP3,POU2F2,RAB27B,ARL4D,SNX10,KCNB2,RPS13,DPP10,PHLDB2,NOP53,PTPRU,TRAM1L1,WNT11,CBY1,ATP1B1,RAB38,SYNJ2BP,PYGO1,DSP,TBC1D16,RANBP2,KPNA3,PRKCB,GBP1,ITGA2,SEPT5,MID1,RAB30,THOC3,RPS20,TNIK,MXI1,TSPAN15,IPO5,LRP4,CMTM8,TNFSF13B,UBAC2,ARL2,KIF5C,GAS6,P2RY1,TSPAN17,NEDD4,ARHGAP44,RPL34,RAB11FIP5,MAP1A,EHD3,PRKG2,TRIM3,SH3PXD2B,DYNC2H1,MYO6,TBC1D9,SEPT3,LCA5,RAB3B,MSX1,RAB6B,RAPGEF2,RPL21,ZDHHC15,FERMT2,PRICKLE1,AGAP2,SKAP1,TLR6,ILDR2,HOMER3,RERE,RPL12,MYADM,NACC2,TERT,MPP7,FBN1,XBP1,MCC,DLG2,RPL4,HK1,RPS12,BMP4,TBC1D4,KIF1B,DDIT3,ABCG1 |
| 4.279e-04 | -7.76 | GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1549 | 191 | 17377 | 1707 |
PPP4R4,ACVR1,ACSL1,DUSP8,FGF13,GRIK2,DNAJC3,LDLR,NPM1,NDRG2,CEBPA,PRKCA,SNX9,PPM1E,PPP1R26,ZFYVE28,ITGB3,RAP2A,PPP2R2B,TLR4,TSHR,SLIT2,RASGRP1,PRKACB,PDGFRB,TNK2,SESN2,GCNT2,SPOCD1,CAP2,TGFA,LRRK2,DEPTOR,PRKAR2B,ACVR2B,INHBC,ENPP1,GPRC5B,NCKAP1L,SH3RF1,ERN1,TNFRSF1A,ADRB1,BMP1,INPP5F,DIRAS1,SPRY4,NRP1,PPARGC1A,MAGI2,MEF2C,PRKAA2,LATS2,FN1,UBASH3B,ITGA6,SORBS3,TNFRSF19,PFN2,DDIT4,MECOM,IGF1R,FLRT3,MYC,C1QL4,LRP6,ADCY6,GPR161,NOS3,HMGCR,FGFR4,PAK1,MSTN,VLDLR,DUSP9,CALCRL,WWC1,STRADB,PLCB1,MAPKAPK2,PMEPA1,PELI2,CSF1,THBS4,INHBE,CDH2,TESC,SMYD3,SFN,NEK10,ID1,AVPI1,CELSR3,IL15,AKAP5,GPR65,NTRK3,LCP2,PIBF1,PPP1R9A,TLR3,DACT1,CNKSR3,ACVR2A,DAB2IP,MARCKS,PDE4D,HSPA2,FZD1,IGFBP3,FER,PDK1,FZD4,PFKFB2,PTPN6,ADCY1,WNT11,ATF3,SYNJ2BP,RARRES2,CD40,FGFR1,MAGI3,SNCA,SMAD3,IRS2,CAMK2N1,RANBP2,CXCL10,NRG3,PTPRJ,GBP1,WFS1,WWTR1,ITGA2,DUSP19,TNFSF15,HGF,GRB10,BMPR1A,MAPK10,MID1,CNTN1,MYO1D,TNIK,FARP1,BMPR2,EDA2R,FZD8,LRP4,HERC5,P2RY1,GAS6,PKN1,EPHB1,TPD52L1,BMP6,PPP2R3A,PRKCD,GHR,AFAP1L2,IQGAP3,ERRFI1,SMAD6,TNFRSF11A,SPRY2,SYK,DUSP1,MOB1B,VEGFC,VAV3,RAPGEF2,CCNG1,GUCY1A2,TLR6,GPLD1,DKK1,GPR37,PTPRC,TRIB3,NSD1,FGR,DOCK7,MYADM,MAP2K6,XBP1,DLG2,LRRK1,BMP4,PKIA,ATP2B4 |
| 4.290e-04 | -7.75 | Mesodermal Commitment Pathway | WikiPathways | WP2857 | 156 | 31 | 5312 | 569 |
EPB41L5,VAV3,ACVR1,BMPR2,FZD4,FZD8,SOX21,ARID5B,YAP1,GATA3,ZIC2,CTBP2,ACVR2B,SESN1,FGFR1,DKK1,SMAD3,DDAH1,TCF7L1,EOMES,ZIC5,RGS10,ACVR2A,SLC2A12,TOX,KLF5,BMPR1A,BMP4,SMAD6,FOXA1,CSRP2 |
| 4.292e-04 | -7.75 | GENTILE_UV_LOW_DOSE_DN | MSigDB lists | GENTILE_UV_LOW_DOSE_DN | 65 | 16 | 17377 | 1707 |
VEGFC,MICAL2,MEIS2,DOCK1,MYO10,XYLT1,SATB2,PIBF1,TBC1D30,PPP2R3A,DDIT4,IGF1R,SEMA3C,MET,CDH2,SLIT2 |
| 4.295e-04 | -7.75 | WEST_ADRENOCORTICAL_TUMOR_DN | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_DN | 528 | 76 | 17377 | 1707 |
CXCR5,PLA2G4A,NBL1,SORBS1,CFH,FLVCR2,DOCK1,NDRG2,NRXN1,SEMA6A,FKBP9,KCNN2,SLC16A2,ALDH1L1,CHRDL1,CNNM2,CTTN,VWA5A,PLTP,CTH,FZD1,SSH3,CD55,MEIS2,COL4A3,FGF12,TNS1,SLC25A28,RARRES2,JAM3,TCF7L1,BDH2,KLF5,HGF,MAPK10,CRYL1,SV2B,IGFBP6,GCAT,LAMC3,KIF5C,SORBS3,CUEDC2,TPD52L1,GAS1,HOPX,ABLIM1,EHD3,SMTN,SREBF1,MOXD1,ZFP36L2,RIMS2,CEBPD,DUSP1,DLGAP1,OPLAH,MID2,MICAL2,NR4A1,COL4A4,ESRRG,RAPGEF4,PHACTR2,C1R,LHPP,LEPR,MGMT,CSF1,PCGF2,PLD1,GEM,CDH2,RNF122,TPT1,ABCG1 |
| 4.309e-04 | -7.75 | response to endogenous stimulus | biological process | GO:0009719 | 1397 | 171 | 17256 | 1658 |
CGN,ACVR1,ACSL1,TRIM16,LDLR,ASS1,GATA3,STAT5B,ITPR2,SKI,FBXO32,TGFBR3,CHRDL1,TLR4,TSHR,SLIT2,PRKACB,PDGFRB,NKX2-1,SESN2,GCNT2,ATF4,SMAD9,NR6A1,ACVR1C,LRRK2,YAP1,PRKAR2B,ABCC2,FGF17,ACVR2B,SESN1,GNAI1,ENPP1,GNB4,MAPK13,OXTR,TNFSF4,PPARGC1A,MAGI2,RRAGD,MEF2C,PRKAA2,LATS2,GNG12,INPPL1,RUNX2,GABRB2,DHCR24,ATP6V1E2,DDIT4,EEF2,CA2,IGF1R,BCHE,FLRT3,SREBF1,LRP6,GRIP1,ADCY6,STXBP1,AGL,CHRM3,NOS3,EPB41L5,PAK1,FGFR4,BDNF,RHOQ,MSTN,FHL2,RYR2,PDE8A,PLCB1,CPEB1,BAIAP2,MMP15,SH3GL2,PMEPA1,HEYL,SH3BP4,RAB31,HOXD13,SMYD3,PRKN,ID1,SORBS1,RBFOX2,NTRK3,ZFYVE9,PLPP1,ASNS,ACVR2A,DAB2IP,PDE4D,SNAI2,FER,UROS,PTPRU,FGF12,ADCY1,FGFR1,SNCA,SMAD3,IRS2,EIF4EBP1,ITGA2,PAM,RGS10,HPGD,KLF5,BMPR1A,NR3C2,PSPH,HEY1,CGB2,ROBO2,BMPR2,ESRP1,IPO5,LRP4,GABRG2,BMP6,NEDD4,NKX6-1,FOXP2,HMGCS1,DSG2,PRKCD,GHR,STC2,GTF2F2,KLF9,ERRFI1,PCK2,SMAD6,SYK,ZFP36L2,ATP2B1,DUSP1,TRPM4,MSX1,GSTM2,PXN,KDM5B,HNF4G,NR4A1,ESRRG,RAPGEF2,FERMT2,GAREM1,MARS,TLR6,LEPR,GPLD1,GALNT3,CEBPB,TRIB3,FAT4,FBN1,CTSV,XBP1,BMP4,TBC1D4,KIF1B,FOXA1,LARP1,ATP2B4,CACNA2D1,ABCG1,ATP1A3 |
| 4.324e-04 | -7.75 | collagen-activated signaling pathway | biological process | GO:0038065 | 12 | 6 | 17256 | 1658 |
COL4A5,COL4A3,DDR1,SYK,UBASH3B,ITGA2 |
| 4.324e-04 | -7.75 | protein phosphorylation | biological process | GO:0006468 | 956 | 123 | 17256 | 1658 |
EPHA3,BTC,NEK10,ACVR1,FGF13,RASAL2,IL15,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,PIBF1,DDR1,STK24,MOK,SPEG,TLR3,RPS6KA2,TGFBR3,RPS6KL1,MYO3B,ACVR2A,DAB2IP,EPHB6,MET,TLR4,PRKACB,RASGRP1,PDGFRB,IGFBP3,FER,TNK2,MYLK3,MARK1,SMAD9,PDK1,ACVR1C,ADM2,PTPN6,KCNH5,LRRK2,PRKCQ,WNT11,ACVR2B,ROR1,FGF17,SGK2,FRK,GRK3,FGFR1,IRS2,DYRK1B,PRKCB,RASGRF2,PLK2,PTK7,ERN1,ABI3,MAP3K21,HGF,MAPK13,OXTR,BMPR1A,MAPK10,MEF2C,MAST1,PRKAA2,TYRO3,LATS2,TNIK,DYRK3,BMPR2,PAK5,SLK,GAS6,PKN1,EPHB1,TNFRSF19,DOK5,EFEMP1,IGF1R,ADCK1,MYC,PRKCD,GHR,SGK3,PRKG1,SGK1,PRKG2,ALPK1,NCAM1,IQGAP3,MAST4,SYK,ZFP36L2,GFRA1,FES,PAK1,FGFR4,IL17RD,RAPGEF2,NUAK2,RASA3,OBSCN,STRADB,DUSP9,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,PELI2,MAP2K6,AKT3,NEK11,GRIN2D,LRRK1,BMP4,MAP3K20,BTRC |
| 4.331e-04 | -7.74 | soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-embryonal | 2716 | 314 | 17385 | 1698 |
DOC2A,MYCBP2,CGN,TCP11L2,PRSS12,DNAJC3,LDLR,NPM1,CTBP2,RAC3,SKI,BAG3,DNAH6,PPFIA2,GSTM3,ATRNL1,BEND4,RCAN3,TSHR,EML6,ACVR1C,DCC,KLHL4,LRRK2,NFIA,EFHC1,ABCC2,ZDHHC14,ENPP1,PLK2,ADRB1,MAPK13,ERCC5,DNHD1,LZTS1,SCN5A,LATS2,ALOX5AP,CELSR1,ZHX3,TBC1D1,CYP2J2,TJP1,WDFY4,NAV1,PDZD7,FLRT3,ZIC5,MPDZ,CADPS2,LMAN2,TSPAN12,ALPK1,AGL,GLIS1,FMNL2,RIMS2,IGSF3,PNP,KCNQ3,ARID5B,FASN,KIAA1324L,RYR2,TTC30A,TTYH2,SMARCD3,HIP1,C1R,PEX5L,CCDC85A,TMEM74,TEX15,VPS37D,ADAMTS3,THBS4,EMILIN2,CDH17,SLFN5,CDH2,AMPD1,TBKBP1,AMOTL1,FAM131C,MYO1B,LRRCC1,OTX1,PKP2,COLEC10,NELL2,TLR3,KMO,POU5F1B,SCRN1,RTKN2,DNAH5,MYT1,DOCK8,SCN3A,NKX3-2,KCNH5,NLGN4X,WNT11,PRKCQ,ATOH1,PYGO1,TTC28,FGFR1,MAGI3,DCBLD2,PRKCB,WFS1,LAMB1,MAP3K21,KLF5,LRRC27,HACE1,CGB2,TMEM132C,ROBO2,GABRR2,INPP1,BEX2,NEDD4,GPR155,RALGAPA2,MORN2,FIG4,MYO6,SMAD6,GFI1,MED12L,VAV3,ARAP2,CACNA1E,MCF2L2,PTPN13,CEBPB,ZFP62,PTPRC,NSD1,TERT,XBP1,MYOM2,TNFRSF17,DOCK6,ATP2B4,OCLN,MVK,ACSL1,TRIM16,KIF5A,FHDC1,CCNJ,LGI2,ARHGEF10L,PPM1E,SIPA1L2,TM9SF2,SEC16B,LRRC6,CPVL,EOMES,HPS1,ITGB3,ANKFN1,SLC2A12,KIAA1614,TLR4,NEB,IL1RAP,PDGFRB,CYP1B1,COL4A3,PNRC1,ABCC4,SPOCD1,ANK2,CAPN5,CR2,PLEKHA1,EML1,TMEM132B,FHAD1,DYRK1B,GSN,NCAM2,ITGBL1,ERN1,TNFRSF1A,OXTR,PPARGC1A,NEUROG2,MAGI2,MOCOS,STXBP5L,OTOGL,LAMC3,SCD,MLC1,SPINK5,NUMBL,IGF1R,ZNF440,PDE10A,SMTN,EBF4,ADCY6,VGLL4,ZNF629,DPYSL5,FGFR4,HBG2,PCDH10,IL17RD,PODXL2,SLITRK2,SH2D2A,MSTN,PARD3B,TMTC4,EFNA3,SDC3,OBSCN,SLITRK5,WWC1,PDE8A,B4GALNT3,FAT1,HEYL,HK2,PTPRN2,PLD1,XKR4,MME,DMXL2,EML5,ZSWIM5,SORBS1,CELSR3,DOCK1,HECW2,COL18A1,ZNF83,DENND3,RADIL,DDX60L,PCLO,CYP26A1,FAM131B,COL22A1,UNC13B,SLC22A17,TACC2,BCL6,MYH15,WWC2,SCN2A,MET,ZNF460,NTNG1,FER,SLC39A8,THSD4,PTPN6,ACO1,AMIGO1,CENPV,ARMC4,PTPRJ,HGF,DISP1,CTNND2,TENM1,COL9A3,BMPR2,GRB14,ARHGEF11,KLHL13,RUSC2,LRP4,NSUN6,COL4A5,CUEDC2,SEL1L3,MAP1A,KIAA0319,TFAP2A,PRICKLE2,KIAA0408,DHRS12,TSPAN13,KIAA1211,USP2,CRIM1,LRRIQ1,ESRRG,SYBU,LITAF,ZFPM2,LEPR,SMPDL3B,RERE,EBF1,ADAMTS17,DOCK7,FAT4,NACC2,FBN1,THSD7B,ZNF474,KIF21A,PTGES,MMP16 |
| 4.331e-04 | -7.74 | embryonal | COSMIC cancer mutations | embryonal | 2716 | 314 | 17385 | 1698 |
DOC2A,MYCBP2,CGN,TCP11L2,PRSS12,DNAJC3,LDLR,NPM1,CTBP2,RAC3,SKI,BAG3,DNAH6,PPFIA2,GSTM3,ATRNL1,BEND4,RCAN3,TSHR,EML6,ACVR1C,DCC,KLHL4,LRRK2,NFIA,EFHC1,ABCC2,ZDHHC14,ENPP1,PLK2,ADRB1,MAPK13,ERCC5,DNHD1,LZTS1,SCN5A,LATS2,ALOX5AP,CELSR1,ZHX3,TBC1D1,CYP2J2,TJP1,WDFY4,NAV1,PDZD7,FLRT3,ZIC5,MPDZ,CADPS2,LMAN2,TSPAN12,ALPK1,AGL,GLIS1,FMNL2,RIMS2,IGSF3,PNP,KCNQ3,ARID5B,FASN,KIAA1324L,RYR2,TTC30A,TTYH2,SMARCD3,HIP1,C1R,PEX5L,CCDC85A,TMEM74,TEX15,VPS37D,ADAMTS3,THBS4,EMILIN2,CDH17,SLFN5,CDH2,AMPD1,TBKBP1,AMOTL1,FAM131C,MYO1B,LRRCC1,OTX1,PKP2,COLEC10,NELL2,TLR3,KMO,POU5F1B,SCRN1,RTKN2,DNAH5,MYT1,DOCK8,SCN3A,NKX3-2,KCNH5,NLGN4X,WNT11,PRKCQ,ATOH1,PYGO1,TTC28,FGFR1,MAGI3,DCBLD2,PRKCB,WFS1,LAMB1,MAP3K21,KLF5,LRRC27,HACE1,CGB2,TMEM132C,ROBO2,GABRR2,INPP1,BEX2,NEDD4,GPR155,RALGAPA2,MORN2,FIG4,MYO6,SMAD6,GFI1,MED12L,VAV3,ARAP2,CACNA1E,MCF2L2,PTPN13,CEBPB,ZFP62,PTPRC,NSD1,TERT,XBP1,MYOM2,TNFRSF17,DOCK6,ATP2B4,OCLN,MVK,ACSL1,TRIM16,KIF5A,FHDC1,CCNJ,LGI2,ARHGEF10L,PPM1E,SIPA1L2,TM9SF2,SEC16B,LRRC6,CPVL,EOMES,HPS1,ITGB3,ANKFN1,SLC2A12,KIAA1614,TLR4,NEB,IL1RAP,PDGFRB,CYP1B1,COL4A3,PNRC1,ABCC4,SPOCD1,ANK2,CAPN5,CR2,PLEKHA1,EML1,TMEM132B,FHAD1,DYRK1B,GSN,NCAM2,ITGBL1,ERN1,TNFRSF1A,OXTR,PPARGC1A,NEUROG2,MAGI2,MOCOS,STXBP5L,OTOGL,LAMC3,SCD,MLC1,SPINK5,NUMBL,IGF1R,ZNF440,PDE10A,SMTN,EBF4,ADCY6,VGLL4,ZNF629,DPYSL5,FGFR4,HBG2,PCDH10,IL17RD,PODXL2,SLITRK2,SH2D2A,MSTN,PARD3B,TMTC4,EFNA3,SDC3,OBSCN,SLITRK5,WWC1,PDE8A,B4GALNT3,FAT1,HEYL,HK2,PTPRN2,PLD1,XKR4,MME,DMXL2,EML5,ZSWIM5,SORBS1,CELSR3,DOCK1,HECW2,COL18A1,ZNF83,DENND3,RADIL,DDX60L,PCLO,CYP26A1,FAM131B,COL22A1,UNC13B,SLC22A17,TACC2,BCL6,MYH15,WWC2,SCN2A,MET,ZNF460,NTNG1,FER,SLC39A8,THSD4,PTPN6,ACO1,AMIGO1,CENPV,ARMC4,PTPRJ,HGF,DISP1,CTNND2,TENM1,COL9A3,BMPR2,GRB14,ARHGEF11,KLHL13,RUSC2,LRP4,NSUN6,COL4A5,CUEDC2,SEL1L3,MAP1A,KIAA0319,TFAP2A,PRICKLE2,KIAA0408,DHRS12,TSPAN13,KIAA1211,USP2,CRIM1,LRRIQ1,ESRRG,SYBU,LITAF,ZFPM2,LEPR,SMPDL3B,RERE,EBF1,ADAMTS17,DOCK7,FAT4,NACC2,FBN1,THSD7B,ZNF474,KIF21A,PTGES,MMP16 |
| 4.341e-04 | -7.74 | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_EFF_MEMORY_CD4_TCELL_UP | 183 | 33 | 17377 | 1707 |
ZNF516,SORBS1,ACSL1,GABRB2,ZCCHC24,CBS,COBLL1,ABHD6,AARS,QPRT,EPB41L3,RSL24D1,CHN2,BACE2,NBEA,MARCH3,LRP12,FES,TBC1D8,FADS1,MEIS2,PRDM13,SMARCD3,PDE8A,CDC42BPA,GALNT3,ITGBL1,FAT1,SH3BP4,NRP1,SMYD3,LARP1,HEY1 |
| 4.341e-04 | -7.74 | GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_UP | MSigDB lists | GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_UP | 183 | 33 | 17377 | 1707 |
GPT2,DOCK1,VAMP8,OPHN1,SLC7A2,MTUS1,CCDC120,RND2,FKBP9,DSG2,GHR,ITGB3,SGK1,SERPINH1,ZNF385A,USP2,DUSP9,SHISA2,C1R,LHPP,PALLD,FRK,NPDC1,DOCK5,SMPDL3B,FGFR1,AK1,ICA1,RND3,ZNF697,MAPK13,NRP1,DOCK6 |
| 4.341e-04 | -7.74 | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_UP | MSigDB lists | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_24H_INCUBATION_UP | 183 | 33 | 17377 | 1707 |
EXPH5,MTG1,PSTPIP2,PTPN21,SLC25A27,PSD3,SPATS2L,BBS9,TBC1D19,ABLIM1,FRY,AFF2,ITGB3,REEP1,RCAN3,TSPAN9,ZNF629,RWDD2A,LCA5,CAP2,GDPD1,PRRG1,NPC2,TBC1D16,HOXA1,RERE,TRIB3,TDO2,P4HA2,TANC2,FNBP1L,PANK3,SLC16A10 |
| 4.341e-04 | -7.74 | V$HFH4_01 | MSigDB lists | V$HFH4_01 | 183 | 33 | 17377 | 1707 |
BCL11B,ID1,TCP11L2,CHCHD7,PLAG1,CREB5,NOVA1,TSPAN17,CYP26A1,NEO1,FOXP2,ATXN7L1,CHN2,KCTD15,PPFIA2,SLC10A7,ZIC5,BCL6,SGK1,TSPAN13,ETV1,GFRA1,PRKACB,CRIM1,MYO10,ESRRG,NFIA,PRDM1,ATOH1,FBXO36,GABARAPL1,MLLT3,MEF2C |
| 4.359e-04 | -7.74 | GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | 198 | 35 | 17377 | 1707 |
SCN5A,UBASH3B,CACNB4,NEDD4,NOS1AP,KCNN2,KCNAB1,SCN1B,AKAP7,CACNB2,TRPC1,TSPAN13,PDE4D,HSPA2,DPP10,KCNIP3,GSTM2,PTPN6,ANK2,JPH1,FGF12,RYR2,GSTO1,ATP1B1,AMIGO1,ASPH,SNCA,CXCL10,KCNG1,BMP4,ATG5,TESC,CACNA2D1,ATP2B4,STOM |
| 4.359e-04 | -7.74 | WIERENGA_STAT5A_TARGETS_UP | MSigDB lists | WIERENGA_STAT5A_TARGETS_UP | 198 | 35 | 17377 | 1707 |
SLC6A9,CFH,RNF144A,GPR65,CBS,PRDM8,IL18R1,NCS1,SLC9A7,DDIT4,CA2,MAP1A,GATA2,HSPA2,SEMA6C,CKAP4,LAMP3,PFKFB4,ANTXR2,MYO10,ARID5B,AK4,TTLL7,GABARAPL1,BATF3,CXCL10,TRIB3,RNF217,P4HA2,ITGA2,SH3BP4,PGM2L1,MAOA,MAPK13,TMEFF2 |
| 4.374e-04 | -7.73 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological process | GO:0070059 | 31 | 10 | 17256 | 1658 |
CEBPB,TRIB3,ATF4,XBP1,ERN1,BBC3,TMEM117,DAB2IP,CHAC1,DDIT3 |
| 4.374e-04 | -7.73 | hippo signaling | biological process | GO:0035329 | 31 | 10 | 17256 | 1658 |
MOB1B,LATS2,AMOTL1,FAT4,WWTR1,DCHS1,YAP1,WWC1,TJP1,SAV1 |
| 4.380e-04 | -7.73 | REACTOME_NEURONAL_SYSTEM | MSigDB lists | REACTOME_NEURONAL_SYSTEM | 275 | 45 | 17377 | 1707 |
KCNV1,GNG12,CACNG3,AKAP5,GRIK2,GABRB2,GABRG2,ABAT,GABRR2,SLC1A3,PRKCA,CACNB4,KCNC4,KCNJ4,RPS6KA2,UNC13B,KCNN2,KCNAB1,CHRNA5,CACNB2,KCNS3,KCNMB3,ADCY6,MYO6,STXBP1,PRKACB,KCNB2,ALDH2,KCNQ3,KCNH5,ADCY1,CHRNA6,SNAP25,KCND3,PLCB1,GJC1,GNAI1,GRIK4,KCNMB4,PRKCB,RASGRF2,GNB4,KCNG1,MAOA,GRIN2D |
| 4.381e-04 | -7.73 | regulation of cellular protein metabolic process | biological process | GO:0032268 | 2568 | 294 | 17256 | 1658 |
PPP4R4,ACVR1,DUSP8,GRIK2,RECK,DNAJC3,LDLR,GATA3,NPM1,CEBPA,CHAC1,PRKCA,SNX9,STK24,NOS1AP,SKI,PPP1R26,TGFBR3,PMAIP1,ZFYVE28,RAP2A,PPP2R2B,RCAN3,EIF4E3,ACVR1C,TGFA,LRRK2,DEPTOR,AGO4,PRKAR2B,ACVR2B,F12,ENPP1,SH3RF1,NCKAP1L,CCBE1,PLK2,BBC3,SERPINI1,DIRAS1,INPP5F,SPRY4,NRP1,SPOCK3,LATS2,SLK,DHCR24,OPHN1,TNFRSF10C,TNFRSF19,GAS1,RPL13A,MECOM,FRY,PAIP2B,MYC,FLRT3,C1QL4,PRELID1,SREBF1,PRR16,ZNF385A,HMGCR,BOD1,RPL26,VLDLR,PACSIN3,HIP1,ARRDC4,PLCB1,FAM162A,CPEB1,BEX4,PMEPA1,PELI2,THBS4,INHBE,LAPTM4B,CDH2,SMYD3,EPHA3,MTG1,PCSK1N,RNF144A,C4A,LCP2,DDR1,TLR3,CNKSR3,DACT1,MAGEA3,DAB2IP,PDE4D,SERPINH1,PERP,FZD1,GAPDH,FZD4,PREX1,ADCY1,ATF3,WNT11,ASPH,FGFR1,MAGI3,SNCA,CXCL10,BEX3,WFS1,APELA,WWTR1,MAP3K21,TNFSF15,BMPR1A,ATG5,MAPK10,MID1,EDA2R,FZD8,IPO5,UBAC2,HERC5,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,GHR,YBX3,ERRFI1,GFI1,SMAD6,SPRY2,ZFP36L2,PARP9,VEGFC,RAPGEF2,GAREM1,RACK1,GPLD1,PTPRC,TRIB3,NSD1,FGR,XBP1,BMP4,LRRK1,ATP2B4,LARP1,BTRC,PHACTR3,ACSL1,FGF13,NDRG2,GSDME,F3,PPM1E,ITGB3,PCOLCE2,EPHB6,ENO1,TLR4,SLIT2,PDGFRB,RASGRP1,PRKACB,LAMP3,TNK2,CD55,ATF4,GCNT2,SESN2,COL4A3,ROR1,INHBC,GSN,GPRC5B,ERN1,C8orf88,TNFRSF1A,NCOA7,PPARGC1A,MAGI2,CACUL1,TYRO3,LONRF1,PRKAA2,FN1,UBASH3B,JDP2,FBXO4,SORBS3,PFN2,SPINK5,DDIT4,RNF180,EEF2,IGF1R,GATA2,LRP6,ADCY6,INAVA,FGFR4,PAK1,ATP5IF1,MSTN,EFNA3,WWC1,STRADB,DUSP9,PDE8A,HERPUD1,MAPKAPK2,CSF1,SEMA3A,TESC,SFN,PRKN,AVPI1,NEK10,ID1,IL15,CELSR3,NTRK3,TNKS1BP1,PIBF1,PPP1R9A,RIDA,CDC14B,BCL6,ACVR2A,FHIT,PROS1,MET,HSPA2,IGFBP3,ALG10B,FER,CSN2,NOP53,PTPN6,ACO1,RNF125,VIM,SYNJ2BP,RARRES2,CD40,C4BPB,WARS,SMAD3,CAMK2N1,NRG3,PTPRJ,RNF217,EIF4EBP1,GBP1,ITGA2,DUSP19,HGF,CNTN1,TENM1,TNIK,NECAB2,BMPR2,PAK5,LRP4,IGF2BP2,BMP6,PPP2R3A,MAP1A,PRKCD,RASD2,EIF1,AFAP1L2,IQGAP3,TNFRSF11A,SYK,DUSP1,MOB1B,CRIM1,PRICKLE1,PHACTR2,CCNG1,TLR6,CTIF,DKK1,GPR37,DOCK7,MYADM,MAP2K6,ACER2,MAP3K20,PKIA |
| 4.394e-04 | -7.73 | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_UP | MSigDB lists | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_UP | 161 | 30 | 17377 | 1707 |
EML5,EVL,PDK1,SIDT1,KDM5B,CELSR3,CHCHD7,CLYBL,PRSS12,RAPGEF4,SELL,TDRKH,PLEKHA1,SESN1,SATB1,KBTBD11,MAGI3,IRS2,ID3,TGFBR3,PMEPA1,MYC,INPP4B,RGS10,SREBF1,ADCY6,BBC3,FHIT,RRAS2,AMPD1 |
| 4.414e-04 | -7.73 | Regulation of cholesterol biosynthesis by SREBP (SREBF) | REACTOME pathways | R-HSA-1655829 | 55 | 14 | 10287 | 971 |
CYP51A1,IDI1,MVK,HMGCS1,INSIG1,SEC24D,MVD,SREBF1,FASN,SMARCD3,SQLE,SCD,DHCR7,HMGCR |
| 4.429e-04 | -7.72 | protein localization to membrane | biological process | GO:0072657 | 421 | 62 | 17256 | 1658 |
RPS20,TNIK,FGF13,GRIK2,TSPAN15,LRP4,PKP2,GAS6,P2RY1,NRXN1,RPL13A,ARHGAP44,RPL34,EPB41L3,PMAIP1,CACNB2,RPS11,REEP1,RAP2A,ZDHHC6,EHD3,RAB26,ZDHHC23,MAP7,LRP6,PRKG2,LIN7A,SH3PXD2B,PACSIN1,CPE,STXBP1,RPS23,KCNB2,RPS13,DPP10,RPL26,ITGB7,KCNIP3,RAPGEF2,ANK2,DCHS1,RPL21,ZDHHC15,FERMT2,ATP1B1,SNAP25,RAB38,ZDHHC14,SKAP1,RPL12,MYADM,RPL28,FCHO2,WDR19,RAB31,TNFRSF1A,DLG2,RPL4,RPS12,CDH2,MAGI2,TESC |
| 4.433e-04 | -7.72 | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | MSigDB lists | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_UP | 59 | 15 | 17377 | 1707 |
FGFR4,MN1,VAV3,ZNF395,ANK2,MORC4,ASS1,PRKAR2B,JAKMIP2,TMEM47,ABAT,TBC1D9,VWA5A,MET,GATM |
| 4.444e-04 | -7.72 | V$NKX25_02 | MSigDB lists | V$NKX25_02 | 244 | 41 | 17377 | 1707 |
INPPL1,KLHL13,CHCHD7,JDP2,GPR65,PLAG1,PTPN21,KCTD12,NRXN1,NEO1,ARHGEF10L,FOXP2,PPM1E,NELL2,KCTD15,ZNF354A,RALGPS2,CNTN4,GRHL1,PPFIBP1,CNNM2,SLC6A15,SMAD6,VGLL4,C15orf41,NKX2-1,RWDD2A,MEIS2,ESRRG,KCNH5,FOXN3,CYTH3,VLDLR,ATOH1,MBNL2,SKAP1,NAP1L5,PTPRC,NSD1,KLF12,SHOX2 |
| 4.447e-04 | -7.72 | RNA polymerase II regulatory region sequence-specific DNA binding | molecular function | GO:0000977 | 661 | 91 | 17224 | 1680 |
CREB3L2,TFCP2L1,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,IKZF3,HLF,BACH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,GLIS1,SMAD6,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 |
| 4.484e-04 | -7.71 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 16 | 7 | 17377 | 1707 |
ACVR2A,ACVR2B,ACVR1,TGFBR3,BMPR1A,BMPR2,ACVR1C |
| 4.484e-04 | -7.71 | GO_REGULATION_OF_PLATELET_AGGREGATION | MSigDB lists | GO_REGULATION_OF_PLATELET_AGGREGATION | 16 | 7 | 17377 | 1707 |
PRKCQ,ABAT,PRKCA,SYK,UBASH3B,PRKCD,PRKG1 |
| 4.578e-04 | -7.69 | Ser/Thr_kinase_AS | interpro domains | IPR008271 | 308 | 49 | 18492 | 1811 |
PRKAA2,TNIK,LATS2,ACVR1,DYRK3,SLK,CHUK,MAPK4,GRK6,PRKCA,PKN1,MOK,SPEG,RPS6KA2,PRKCD,SGK3,PRKG1,MYO3B,ACVR2A,PRKG2,SGK1,MAST4,PRKACB,PAK1,MYLK3,MARK1,ACVR1C,LRRK2,NUAK2,OBSCN,PRKCQ,ACVR2B,CDC42BPA,SGK2,GRK3,DYRK1B,MAPKAPK2,PRKCB,PKN3,MAP2K6,AKT3,PLK2,ERN1,MAP3K21,NEK11,BMPR1A,MAPK10,MAP3K20,MAST1 |
| 4.580e-04 | -7.69 | GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_DN | MSigDB lists | GSE22443_NAIVE_VS_ACT_AND_IL2_TREATED_CD8_TCELL_DN | 191 | 34 | 17377 | 1707 |
ENO2,FN1,HEBP1,MLF1,CMTM8,COL18A1,DDR1,COL14A1,GAS1,GRPEL2,ASNS,SLC22A17,TSC22D1,CPXM2,GSTM3,ERRFI1,SMPDL3A,PDGFRB,USP2,TMEM43,CAPN5,WNT11,ABCC2,BEX4,CEBPB,IFT81,ID3,P4HA2,BMP1,PAX9,PTGES,SFN,HEY1,CRYL1 |
| 4.580e-04 | -7.69 | GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP | MSigDB lists | GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP | 191 | 34 | 17377 | 1707 |
CELSR1,ENO2,ITGA6,EPS8,CA8,DDIT4,ZNF354A,REEP1,TSC22D1,TSPAN12,ST8SIA1,PROS1,NCAM1,DBN1,SH3BP2,EVL,PNRC1,UROS,NR6A1,SLC39A8,WLS,VLDLR,CHRNA6,AK4,TLR6,BEX4,DOCK7,RIMKLB,INSIG1,GNB4,RASGRF2,LAPTM4B,ZNF808,RRAGD |
| 4.580e-04 | -7.69 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | 191 | 34 | 17377 | 1707 |
EML5,PRSS12,GATA3,SELL,NPM1,KCTD12,CD7,SATB1,SKI,MCOLN2,BAG3,SIPA1L2,EOMES,MYC,EIF1,ZFP36L2,DUSP1,ANTXR2,ATF4,EVL,SLC3A2,PNRC1,PDK1,GSTO1,PLEKHA1,RABAC1,TLR6,SESN1,RERE,PAM,RGS10,ZBTB20,LARP1,ABCG1 |
| 4.580e-04 | -7.69 | GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN | MSigDB lists | GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN | 191 | 34 | 17377 | 1707 |
RGS16,TTC39B,CHCHD7,RHOD,CYP4V2,KCTD12,ADSSL1,SNX9,NEDD4,MCOLN2,CA2,TM9SF2,TSC22D1,CPE,PERP,RHOQ,SKAP2,GJB2,WLS,CYTH3,LRMP,TMEM126A,LITAF,GSTO1,DOCK5,HERPUD1,GLCE,GABARAPL1,ARHGAP21,OSBPL5,SQLE,SERPINI1,SLC1A5,PSPH |
| 4.580e-04 | -7.69 | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN | MSigDB lists | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN | 191 | 34 | 17377 | 1707 |
EPHA3,PLSCR4,ARHGEF11,GRB14,CCDC110,SCN8A,BCL6B,MAPK4,SLC19A2,NEO1,MECOM,NAV1,ALDOC,MPPED2,LIN7A,MET,JAM2,NTNG1,ZNF385A,DPYSL5,EPB41L5,EBPL,TBC1D8B,SFXN4,MPP1,PARD3B,AK4,C1R,MGMT,AHRR,PAM,SQLE,SH3BGRL2,LPP |
| 4.580e-04 | -7.69 | GSE3039_B2_VS_B1_BCELL_UP | MSigDB lists | GSE3039_B2_VS_B1_BCELL_UP | 191 | 34 | 17377 | 1707 |
CXCR5,ARHGAP26,MPZL3,AVPI1,STXBP6,HEBP1,ARL15,SCD,KIF21B,IKZF2,KBTBD11,IL18R1,SPIRE1,SYCP2,GALNT1,TGFBR3,ITGB3,SLC16A9,TBC1D9,ETV1,CRIM1,FOXN3,NR4A1,CYTH3,CD40,ISG20,SNCA,TIFA,PLAGL1,MFSD9,INPP4B,TNFRSF1A,FBRSL1,PHC1 |
| 4.620e-04 | -7.68 | GO_MUSCLE_ORGAN_DEVELOPMENT | MSigDB lists | GO_MUSCLE_ORGAN_DEVELOPMENT | 260 | 43 | 17377 | 1707 |
BVES,ASS1,PKP2,DNER,SKI,FOXP2,SPEG,TGFBR3,EOMES,EEF2,KCNAB1,SMTN,COL19A1,MYH15,ETV1,NEB,FZD1,MSX1,USP2,MSTN,JPH1,ARID5B,MEF2B,RYR2,ATF3,ZFPM2,DSP,HEG1,MKX,ID3,CXCL10,MSC,HLF,PLAGL1,HEYL,XBP1,SVIL,KLF5,DISP1,KLHL31,TPM1,SHOX2,MEF2C |
| 4.624e-04 | -7.68 | protein O-linked glycosylation via serine | biological process | GO:0018242 | 21 | 8 | 17256 | 1658 |
GALNT3,GALNT1,GALNT12,GALNT6,GALNT17,GALNT13,GALNT18,GALNT14 |
| 4.629e-04 | -7.68 | BMP signaling | KEGG pathways | M00679 | 20 | 8 | 7161 | 730 |
ACVR1,SMAD9,BMPR2,ACVR2A,BMP4,BMPR1A,ACVR2B,BMP6 |
| 4.629e-04 | -7.68 | BMP signaling | KEGG pathways | hsa_M00679 | 20 | 8 | 7161 | 730 |
ACVR1,SMAD9,BMPR2,ACVR2A,BMP4,BMPR1A,ACVR2B,BMP6 |
| 4.635e-04 | -7.68 | GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_DEVELOPMENT | 454 | 67 | 17377 | 1707 |
EPHA3,NBL1,AKAP5,NTRK3,RAC3,SEMA6A,PPP1R9A,RND2,BCL6,DAB2IP,MARCKS,PACSIN1,ZNF488,SLIT2,MYLK3,GCNT2,PREX1,YAP1,FEZ1,AMIGO1,ATOH1,FGFR1,BCL11A,SMAD3,GPRC5B,PTK7,WWTR1,HGF,NRP1,MAGI2,COBL,MEF2C,CNTN1,BMPR2,ROBO2,FN1,PTPRD,PLAG1,APBB1,GDPD5,BMP6,NKX6-1,NUMBL,GATA2,SCN1B,SGK1,FIG4,FES,RIMS2,EPB41L5,VEGFC,DISC1,BDNF,RAPGEF2,VLDLR,SMARCD3,BAIAP2,CPEB1,MAP1B,NEGR1,MYADM,CSF1,HEYL,BMP4,SHOX2,SEMA3A,FOXA1 |
| 4.643e-04 | -7.68 | cytoskeleton | cellular component | GO:0005856 | 2120 | 244 | 18223 | 1724 |
ARHGAP26,CGN,FGF13,KIF5A,PTPN21,ACTL8,TUBE1,NPM1,ENAH,RAC3,CEP85L,SKI,PLS3,TUBB4A,DNAH6,POF1B,PPP2R2B,CTTN,TLN2,MYRIP,NEB,PRKACB,DBN1,MARK1,ATF4,DCDC1,EML6,KLHL3,CAP2,ANK2,KLHL4,DSTN,LRMP,FEZ1,PRKAR2B,EFHC1,TNS1,ROR1,COTL1,INTS6,EML1,GNAI1,TRIM9,GSN,WIPF3,MAP2,PLK2,CCDC181,CCDC146,MAP9,ALDOA,TMOD2,TPM1,NRP1,DNHD1,FRMD5,RRAGD,GNG12,LATS2,INPPL1,HID1,DHCR24,OPHN1,SORBS3,TJP1,LRRC49,GPSM2,DYNC1I1,PFN2,BBS9,SPIRE1,FHOD3,MTUS1,ABLIM1,NAV1,SLC7A11,FRY,SMTN,GAN,FIGN,STXBP1,CKAP4,RIMS2,NOS3,BOD1,EPB41L5,PAK1,MID2,DISC1,RHOQ,PNP,MYO10,HIP1,PLS1,SNAP25,CDC42BPA,SPATA7,BAIAP2,BEX4,MAPKAPK2,PLEKHH2,RIPOR2,WDR19,MPP2,RAI14,DYNC2LI1,FNBP1L,CDH2,SHTN1,FRMPD3,EML5,DNM3,SORBS1,ID1,NEK10,TCTN2,TMSB15A,PSTPIP2,MYO1B,LRRCC1,HECW2,ADD2,PKP2,KIF21B,FAM110B,RADIL,TNKS1BP1,PIBF1,PCLO,TBC1D30,PPP1R9A,DOCK2,CTNNA2,SCIN,CCDC120,EPB41L3,TACC2,CDC14B,KAZN,ALDOC,MYO3B,MAP7,MYH15,RTKN2,MARCKS,PDE4D,DNAH5,ZNF365,SNX10,HSPA2,GLI1,INTU,PHLDB2,FER,SSH3,EVL,MYLK3,GAPDH,TMEM67,TUBA1A,NPM3,SHANK2,VIM,PRKCQ,CBY1,DSP,TTLL7,TTC28,CENPV,GABARAPL1,SNCA,PATJ,ARMC4,RANBP2,ARHGAP21,IFT81,GYPC,GBP1,CCNA1,ATG5,SEPT5,MID1,COBL,MAST1,TENM1,WASF3,TNIK,MYO1D,FARP1,KIZ,CKAP2,ARL2,KIF5C,IGF2BP2,ADGRB2,FSD1,RAB11FIP5,MAP1A,GAS2L3,GTF2F2,RMDN2,TFAP2A,ACTA2,SH3PXD2B,DYNC2H1,MYO6,SEPT3,SPRY2,FES,ULBP1,PDLIM7,B9D1,LZTS3,SYNPO2,USP2,PXN,LCA5,PTPN13,MPP1,SYBU,FERMT2,ARHGAP32,CTTNBP2NL,PALLD,SNTB1,PEAK1,MAP10,MAP1B,FGR,MYADM,EDA,MAP2K6,SVIL,NEK11,UACA,MYOM2,KIF21A,GEM,KIF1B,NPHP1,FILIP1,TPT1,SNPH,STOM |
| 4.655e-04 | -7.67 | cell-substrate adhesion | biological process | GO:0031589 | 165 | 30 | 17256 | 1658 |
EPB41L5,TYRO3,FER,ITGB7,SORBS1,PXN,ID1,FN1,FZD4,BVES,RHOD,ITGA6,FERMT2,SORBS3,GAS6,EPHB1,PEAK1,RADIL,DDR1,JAM3,EPDR1,EDA,HPSE,PPFIA2,LAMB1,ITGB3,ITGA2,CTTN,NRP1,SMAD6 |
| 4.696e-04 | -7.66 | cation transport | biological process | GO:0006812 | 805 | 106 | 17256 | 1658 |
PRKN,CACNG3,FGF13,ATP8A1,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC9A7,NCS1,KCNAB1,KCNN2,SLC22A18,SLC10A7,KCNS3,SERINC2,TRPC1,CNNM2,SLC2A12,STEAP3,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,CSN2,KLHL3,SLC9C1,SLC39A8,ANK2,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,ABCC2,KCND3,ATP1B1,ATP10D,SNCA,SFXN1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,TMEM63C,SERINC5,SCN5A,SLC6A9,SCN8A,ATP6V1E2,SLC36A4,GAS6,SLC1A3,SLC12A6,NDFIP2,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,CACNB2,BHLHA15,KCNMB3,SGK1,SLC6A15,NIPAL2,FAM155A,SYK,ATP2B1,TRPM4,NDUFA4L2,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RYR2,CALCRL,RASA3,STEAP1,PTPRC,TMCO3,CACHD1,KCNK15,SLC2A6,GRIN2D,SLC1A5,TRPC3,DDIT3,CACNA2D1,ATP2B4,TPT1,ATP1A3 |
| 4.696e-04 | -7.66 | GO_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | MSigDB lists | GO_CELL_COMMUNICATION_INVOLVED_IN_CARDIAC_CONDUCTION | 36 | 11 | 17377 | 1707 |
SCN5A,SCN1B,CACNB2,ANK2,DSG2,RYR2,PKP2,ATP1B1,DSP,ATP1A3,GJC1 |
| 4.702e-04 | -7.66 | regulation of cellular response to stress | biological process | GO:0080135 | 672 | 91 | 17256 | 1658 |
PRKN,THOC5,GRIK2,DNAJC3,NPM1,NTRK3,EYA4,STK24,BAG3,TLR3,TGFBR3,PMAIP1,DACT1,FAM168A,RAP2A,MAGEA3,BCL6,DAB2IP,MET,ZNF365,TLR4,ENO1,SNAI2,RASGRP1,FZD1,ATF4,FZD4,LRRK2,ATF3,MAGI3,PYCR1,RANBP2,INSIG1,SH3RF1,PLK2,WFS1,ERN1,MAP3K21,NCOA7,DUSP19,PTPRS,HGF,INPP5F,BMPR1A,MID1,TNIK,DYRK3,EDA2R,FZD8,FBXO4,APBB1,UBAC2,PKN1,EPHB1,TNFRSF19,TPD52L1,MECOM,IGF1R,MYC,PRKCD,INAVA,YBX3,FIGN,TNFRSF11A,SYK,ZNF385A,PARP9,HMGCR,PAK1,RPL26,MSX1,NSD2,PDE8A,RACK1,TLR6,PLCB1,MGMT,HERPUD1,DKK1,GPR37,MAPKAPK2,TEX15,DDAH1,NACC2,TERT,AKT3,XBP1,SEMA3A,MAP3K20,DDIT3,TPT1 |
| 4.711e-04 | -7.66 | kinase activity | molecular function | GO:0016301 | 855 | 113 | 17224 | 1680 |
EPHA3,BTC,NEK10,MVK,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,PFKFB2,KCNH5,LRRK2,PANK1,PRKCQ,ACVR2B,FGF17,ROR1,SGK2,FRK,GRK3,FGFR1,MAGI3,TPK1,IRS2,DYRK1B,AK1,PRKCB,PTK7,PLK2,ERN1,MAP3K21,MAPK13,PIK3C2B,HGF,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,EFEMP1,IGF1R,PIK3AP1,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FES,PFKFB4,FGFR4,PAK1,HYKK,CRIM1,MPP1,EFNA3,NUAK2,OBSCN,AK4,STRADB,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,PELI2,AKT3,MAP2K6,MPP2,HK2,NEK11,PGM2L1,PIP5KL1,DLG2,HK1,LRRK1,CMPK2,MAP3K20,PANK3 |
| 4.712e-04 | -7.66 | TTGCACT,MIR-130A,MIR-301,MIR-130B | MSigDB lists | TTGCACT,MIR-130A,MIR-301,MIR-130B | 372 | 57 | 17377 | 1707 |
EFNB2,LONRF1,CCDC126,ACVR1,TRIM2,ACSL1,RUNX2,ROBO2,BMPR2,LRP4,LDLR,HECW2,RASD1,CREB5,DOCK3,CANX,FSTL5,ZFYVE9,TRPS1,RTN1,AKAP7,MPPED2,TRIM3,NBEA,COL19A1,FAM155B,MYT1,VGLL4,MED12L,TBC1D8,RNF145,SOX21,RAPGEF4,SHANK2,SYBU,ADCY1,MAFB,PHACTR2,PEX5L,ATP11A,SNAP25,ZFPM2,MFSD6,PLCB1,DCBLD2,ZNF711,ARHGAP21,BACH2,PMEPA1,CSF1,PGM2L1,SFMBT1,DSEL,NRP1,NR3C2,RAB30,SNPH |
| 4.718e-04 | -7.66 | GSE6259_CD4_TCELL_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_CD4_TCELL_VS_CD8_TCELL_UP | 169 | 31 | 17377 | 1707 |
EFNB2,GPT2,PDLIM7,RGS16,GPM6A,IGFBP6,LGR4,COBLL1,CHSY1,NHP2,NPDC1,FAM162A,JAM3,FGFR1,GAS1,TSKU,DCBLD2,LGI2,RTN1,PLEKHH2,GPRC5B,FAT1,CSF1,EMILIN2,WWTR1,SRGAP1,TSC22D1,PTPRS,ZBTB20,DSEL,ATP2B4 |
| 4.732e-04 | -7.66 | V$AREB6_04 | MSigDB lists | V$AREB6_04 | 237 | 40 | 17377 | 1707 |
EFNB2,TFCP2L1,MXI1,CCDC148,FGF13,TJP1,RNF24,CADM2,PCDH7,TRPS1,LGI2,FOXP2,MAP1A,IGF1R,SLC7A11,PCBP4,ZNF521,JAKMIP2,FES,FZD1,NDUFA4L2,BDNF,MEIS2,PXN,NR6A1,FOXN3,ESRRG,MAFB,PRDM1,SNAP25,BCL11A,KLF12,ITGBL1,GNB4,KLF5,DLG2,BMP4,TNFRSF17,PURG,FOXA1 |
| 4.766e-04 | -7.65 | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | molecular function | GO:0000982 | 416 | 62 | 17224 | 1680 |
CREB3L2,BCL11B,KLF8,RUNX2,PLAG1,JDP2,OTX1,GATA3,STAT5B,CEBPA,ZNF219,NKX6-1,FOXP2,GRHL1,GATA2,MYC,SREBF1,EBF4,TFAP2A,POU2F2,GFI1,ETV1,ENO1,SNAI2,CEBPD,RAX,KCNIP3,ATF4,MEIS2,MSX1,HNF4G,NR6A1,SOX21,NKX3-2,NR4A1,NFIA,LITAF,MAFB,MEF2B,ATF3,SATB2,PRDM1,ATOH1,ZFPM2,BATF,ZIC1,BCL11A,BATF3,EBF1,CEBPB,HLF,NACC2,HEYL,ZBTB20,KLF5,HOXD13,DBP,NKX2-8,SIX2,DDIT3,FOXA1,MEF2C |
| 4.772e-04 | -7.65 | parotid | COSMIC cancer mutations | parotid | 584 | 82 | 17385 | 1698 |
MVK,ACVR1,ZNF311,NPM1,CHUK,NTRK3,GRK6,PRKCA,DDR1,CBLN1,STK24,TXNRD3,SPEG,ZNF827,RPS6KA2,RPS6KL1,ACVR2A,MET,DNAH5,OR2W3,MYT1,PRKACB,PDGFRB,TNK2,EML6,PDK1,TGFA,ACVR2B,ATP1B1,FGFR1,CAMK2N1,AK1,PRKCB,PLK2,PTK7,MAPK13,ERCC5,PIK3C2B,KLF5,BMPR1A,LIFR,LATS2,KLF8,TNIK,MRC2,STOX2,CHCHD7,PLAG1,APBA1,ARHGAP44,NEO1,CHN2,IGF1R,AFF2,SGK1,SYK,FES,PAK1,FGFR4,BCL7A,IL17RD,CRIM1,MYO10,GSTM4,ARID5B,AK4,PDE8A,CDC42BPA,PALLD,DAGLA,MAPKAPK2,TEX15,NSD1,TRIB3,FGR,CECR2,AKT3,MAP2K6,HK2,HK1,TBC1D4,DDIT3 |
| 4.793e-04 | -7.64 | LI_INDUCED_T_TO_NATURAL_KILLER_UP | MSigDB lists | LI_INDUCED_T_TO_NATURAL_KILLER_UP | 284 | 46 | 17377 | 1707 |
CXCR5,DYRK3,LGALS3,SIDT1,CHSY1,CD7,DENND3,PRR7,GDPD5,IL18R1,SLC19A2,SCIN,HOPX,CYP51A1,BAG3,HMGCS1,MSMO1,PRELID2,SGK1,ERRFI1,PLTP,LRP12,FES,PDLIM7,SUSD3,ITGB7,GCNT2,SH3BP2,TES,TMEM126A,FHL2,LITAF,VIM,CCNG1,COTL1,BATF,MFSD6,BATF3,TMEM154,ALDOA,XBP1,EMILIN2,SLC2A6,C1orf21,HK2,LRRK1 |
| 4.800e-04 | -7.64 | MODULE_342 | MSigDB lists | MODULE_342 | 199 | 35 | 17377 | 1707 |
NBL1,KLF8,SORBS1,RHOBTB1,STXBP6,GATA3,CYP26A1,TRPS1,EPCAM,BACE2,MAP7,MYO6,ZFP36L2,DZANK1,VAV3,SSH3,GSTM2,MYO10,GSTM4,WLS,WWC1,DSP,C4orf19,C4BPB,TSKU,GALNT3,GPRC5B,FAT1,GPR160,CDH17,HPGD,BMP4,PPARGC1A,OCLN,FOXA1 |
| 4.800e-04 | -7.64 | V$LEF1_Q2 | MSigDB lists | V$LEF1_Q2 | 199 | 35 | 17377 | 1707 |
PLA2G4A,CGN,SORBS1,DYRK3,SLC6A9,RASAL2,RIMKLA,DHCR24,HMCN1,ZFYVE9,NAV1,RALGPS2,CACNB2,MPPED2,SLC16A9,IQGAP3,ZNF488,GFRA1,GAB2,PTCH2,PAK1,ESRRG,DCHS1,PANK1,EDEM3,SLC25A28,TCERG1L,DKK1,TSKU,RERE,PTPRJ,ENTPD7,DLG2,RAB30,TLL2 |
| 4.801e-04 | -7.64 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_DN | 184 | 33 | 17377 | 1707 |
KLF8,ZNF516,RBFOX2,ZCCHC24,COL4A5,CHSY1,DOK5,F3,RPS6KA2,TGFBR3,UNC13B,BCHE,FBXL2,MYO6,MOXD1,SLIT2,COL6A2,DNAJC6,FHL2,PRRG1,VIM,CLN5,TBC1D16,NPDC1,LEPR,ATP10D,HOMER3,DKK1,TMCO3,GPRC5B,NACC2,EIF4EBP1,CDH2 |
| 4.801e-04 | -7.64 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_UP | 184 | 33 | 17377 | 1707 |
CREB3L2,RUNX2,ALOX5AP,SIDT1,SETBP1,COBLL1,HERC5,GAS6,RGS7,EPHB1,SEL1L3,RPS6KA2,MAP1A,TM9SF2,SLC7A11,KMO,DACT1,TSPAN13,PTPRCAP,GFI1,CRIM1,NPC2,BCL11A,MAPKAPK2,PRKCB,PTK7,MAP2K6,WDR19,SLC7A5,AHNAK2,PTPRS,NRP1,TBC1D4 |
| 4.802e-04 | -7.64 | TGFB_receptor | interpro domains | IPR000333 | 12 | 6 | 18492 | 1811 |
ACVR2A,BMPR1A,ACVR2B,ACVR1,BMPR2,ACVR1C |
| 4.826e-04 | -7.64 | ventricular septum development | biological process | GO:0003281 | 67 | 16 | 17256 | 1658 |
ACVR1,BMPR2,GATA3,NSD2,WNT11,PRDM1,ZFPM2,SAV1,HEG1,TGFBR3,HEYL,PTK7,BMP4,SMAD6,HEY1,FZD1 |
| 4.841e-04 | -7.63 | V$OCT_C | MSigDB lists | V$OCT_C | 245 | 41 | 17377 | 1707 |
REL,STXBP6,PLXNA2,CADM2,NRXN1,IKZF2,FOXG1,NEDD4,PPP2R3A,FSTL5,MTUS1,CDR2L,GALNT1,ZNF362,LRRN1,COL25A1,LHX6,RAB26,PRICKLE2,SLC6A15,TSPAN13,PDE4D,ETV1,SEMA6C,GAB2,GPM6A,GCNT2,FZD4,STAT4,NFIA,FGF12,PRDM1,EML1,EBF1,TCF7L1,MAP2K6,TMOD2,ZBTB20,DLG2,RAB30,TLL2 |
| 4.849e-04 | -7.63 | collagen trimer | cellular component | GO:0005581 | 88 | 19 | 18223 | 1724 |
COL9A3,COL6A2,C1QTNF3,COL4A3,COL4A4,MSR1,COL18A1,COL4A5,COLEC10,COL14A1,COL27A1,COL22A1,EDA,CCBE1,COL25A1,EMILIN2,C1QL4,COL19A1,COL9A2 |
| 4.852e-04 | -7.63 | pancreas-carcinoma-acinar_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-acinar_carcinoma | 2028 | 241 | 17385 | 1698 |
DOC2A,UGT8,TRIM16,PTPN21,LILRB1,ENAH,CTBP2,CADM2,SYT14,DOCK3,NOVA1,HMCN1,SLCO3A1,HECTD2,SKI,EPDR1,CPNE2,FKBP9,TM9SF2,DNAH6,CTTN,TMEM37,PLTP,TLR4,KLHL29,IL1RAP,NEB,NKX2-1,TBC1D8,TNK2,MARK1,SESN2,COL4A3,NR6A1,ANK2,FAM201A,NFE2L1,EFHC1,FGF17,TCERG1L,GPC6,TSKU,TRIM9,TMEM132B,GPRC5B,ATP7B,ERN1,SEMA3C,ZBTB20,DNHD1,APBA2,TC2N,SEMA6B,MRC2,INPPL1,FN1,CELSR1,RHOBTB1,SEC24D,PTPRD,TBC1D1,CYP2J2,ITGA6,LAMC3,WDFY4,PHGDH,FHOD3,CHN1,SYCP2,RNF180,KIAA0895,BNIP1,RALGPS2,IGF1R,EEF2,ABCA5,BCHE,FRAS1,SAMD11,EBF4,SREBF1,SRGAP1,HS3ST5,LIMCH1,FAR2,FBXL2,MOXD1,AGL,FMNL2,CAND2,IGSF3,FADS1,CDH26,IL17RD,SLC37A1,MYO10,PLEKHA8,COL4A4,PARD3B,STAT4,MGST3,TMTC4,SPATA13,TTC30A,WWC1,OBSCN,HIP1,SLITRK5,PDE8A,KHDRBS2,HERPUD1,DHX32,DAGLA,NAP1L5,PLEKHH2,RIMKLB,THBS4,FAT1,CECR2,MATN2,SLC2A6,PTPRN2,TRPC3,SMYD3,AMPD1,CXCR5,TFCP2L1,EML5,AMOTL1,DNM3,CFH,CELSR3,PSTPIP2,LPCAT2,ZNF311,HECW2,COL18A1,PKP2,COBLL1,KIF21B,DENND3,PIBF1,DOCK2,PCLO,TIAM2,CYP26A1,TXNRD3,ZNF827,SPEG,EPB41L3,COL22A1,POU5F1B,COL25A1,PPFIBP1,NBEA,ACVR2A,NAP1L3,MDH1B,MET,DNAH5,ZNF460,GATM,KCNB2,GLI1,SUSD3,DPP10,COL6A2,GAPDH,B3GALT1,RNF145,EBPL,PRDM13,ENTPD1,RANBP2,ANKRD31,POPDC3,KCNG1,PAM,P4HA1,DBP,HS3ST3B1,KLHL31,LIFR,CTNND2,ANO10,SERINC5,ANKRD13D,LPAR2,FZD8,CD276,PLAG1,COL4A5,CREB5,GDPD5,KCNC4,TSPAN17,COL27A1,ARHGAP44,LRRN1,FUT9,MGAT1,GPR155,PCK2,SPRY2,KIAA1211,MED12L,FES,PDLIM7,CARD6,ARHGEF28,LCA5,TMEM126A,SYBU,NUAK2,PRRG1,PRICKLE1,FERMT2,ZFPM2,GUCY1A2,SKAP1,GALNT14,ILDR2,OR2T33,FAT4,TERT,FBN1,NACC2,OSBPL5,SLCO5A1,KIAA0513,MYOM2,KIF21A,CERS1,GEM,DOCK6,ATP2B4,PKIA,FOXA1,FILIP1,STOM,ATP1A3 |
| 4.852e-04 | -7.63 | acinar_carcinoma | COSMIC cancer mutations | acinar_carcinoma | 2028 | 241 | 17385 | 1698 |
DOC2A,UGT8,TRIM16,PTPN21,LILRB1,ENAH,CTBP2,CADM2,SYT14,DOCK3,NOVA1,HMCN1,SLCO3A1,HECTD2,SKI,EPDR1,CPNE2,FKBP9,TM9SF2,DNAH6,CTTN,TMEM37,PLTP,TLR4,KLHL29,IL1RAP,NEB,NKX2-1,TBC1D8,TNK2,MARK1,SESN2,COL4A3,NR6A1,ANK2,FAM201A,NFE2L1,EFHC1,FGF17,TCERG1L,GPC6,TSKU,TRIM9,TMEM132B,GPRC5B,ATP7B,ERN1,SEMA3C,ZBTB20,DNHD1,APBA2,TC2N,SEMA6B,MRC2,INPPL1,FN1,CELSR1,RHOBTB1,SEC24D,PTPRD,TBC1D1,CYP2J2,ITGA6,LAMC3,WDFY4,PHGDH,FHOD3,CHN1,SYCP2,RNF180,KIAA0895,BNIP1,RALGPS2,IGF1R,EEF2,ABCA5,BCHE,FRAS1,SAMD11,EBF4,SREBF1,SRGAP1,HS3ST5,LIMCH1,FAR2,FBXL2,MOXD1,AGL,FMNL2,CAND2,IGSF3,FADS1,CDH26,IL17RD,SLC37A1,MYO10,PLEKHA8,COL4A4,PARD3B,STAT4,MGST3,TMTC4,SPATA13,TTC30A,WWC1,OBSCN,HIP1,SLITRK5,PDE8A,KHDRBS2,HERPUD1,DHX32,DAGLA,NAP1L5,PLEKHH2,RIMKLB,THBS4,FAT1,CECR2,MATN2,SLC2A6,PTPRN2,TRPC3,SMYD3,AMPD1,CXCR5,TFCP2L1,EML5,AMOTL1,DNM3,CFH,CELSR3,PSTPIP2,LPCAT2,ZNF311,HECW2,COL18A1,PKP2,COBLL1,KIF21B,DENND3,PIBF1,DOCK2,PCLO,TIAM2,CYP26A1,TXNRD3,ZNF827,SPEG,EPB41L3,COL22A1,POU5F1B,COL25A1,PPFIBP1,NBEA,ACVR2A,NAP1L3,MDH1B,MET,DNAH5,ZNF460,GATM,KCNB2,GLI1,SUSD3,DPP10,COL6A2,GAPDH,B3GALT1,RNF145,EBPL,PRDM13,ENTPD1,RANBP2,ANKRD31,POPDC3,KCNG1,PAM,P4HA1,DBP,HS3ST3B1,KLHL31,LIFR,CTNND2,ANO10,SERINC5,ANKRD13D,LPAR2,FZD8,CD276,PLAG1,COL4A5,CREB5,GDPD5,KCNC4,TSPAN17,COL27A1,ARHGAP44,LRRN1,FUT9,MGAT1,GPR155,PCK2,SPRY2,KIAA1211,MED12L,FES,PDLIM7,CARD6,ARHGEF28,LCA5,TMEM126A,SYBU,NUAK2,PRRG1,PRICKLE1,FERMT2,ZFPM2,GUCY1A2,SKAP1,GALNT14,ILDR2,OR2T33,FAT4,TERT,FBN1,NACC2,OSBPL5,SLCO5A1,KIAA0513,MYOM2,KIF21A,CERS1,GEM,DOCK6,ATP2B4,PKIA,FOXA1,FILIP1,STOM,ATP1A3 |
| 4.872e-04 | -7.63 | skin-arm-malignant_melanoma | COSMIC cancer mutations | skin-arm-malignant_melanoma | 1332 | 166 | 17385 | 1698 |
MYCBP2,PPP4R4,GRIK2,KIF5A,LDLR,PTPN21,LILRB1,PRKCA,NOVA1,RAC3,HMCN1,TRPS1,EPCAM,CPNE2,FBXO32,KCNAB1,GRHL1,DNAH6,SLC16A2,SERINC2,LIN7A,KIAA1614,SLC2A12,VWA5A,PTPRE,TLR4,SLIT2,ZNF391,ATL1,DCDC1,DCC,ANK2,DSTN,LRRK2,MSRB3,CR2,TNS1,EML1,TRIM9,TMEM132B,GPRC5B,MAP2,CCBE1,RASGRF2,TECPR2,ERCC5,ZBTB20,PPARGC1A,MAGI2,GPT2,SV2B,CELSR1,PTPRD,ATP6V1E2,GALNT13,FOXG1,SPINK5,CHD5,FHOD3,MECOM,SEMA4F,APLF,CACNB2,LRP6,SLC16A9,LOXL4,NIPAL2,FAM155A,ZNF518B,GLIS1,CHRM3,PARD3B,STAT4,RAPGEF4,KIAA1324L,PDE8A,PRDM1,SNAP25,KHDRBS2,GRIK4,XKR9,ADAMTS3,SH3BP4,INHBE,PTPRN2,OSBPL6,DMXL2,SORBS1,CFH,ST14,GALNT6,XYLT1,HECW2,KIF21B,TNKS1BP1,ZSCAN5A,COL22A1,NELL2,PPFIBP1,MAP7,MET,DNAH5,NTNG1,SCN3A,DOCK8,KCNB2,SEMA6C,GLI1,DPP10,FER,MYLK3,B3GALT1,FZD4,TDRD3,KCNH5,NLGN4X,TCEAL3,ENTPD1,IQCK,PTPRJ,IQCH,BACH2,GBP1,PTK7,LAMB1,CCNA1,PTPRS,TNFSF15,MID1,MAN2B2,WDR17,ENO2,PRSS16,CLGN,IPO5,COL4A5,SLC12A6,EPHB1,RGS7,COL27A1,NEDD4,RAB11FIP5,PRKCD,GAS2L3,EHD3,IQGAP3,ARAP2,PTPN13,PRICKLE1,SNTB1,RERE,PTPRC,DPY19L2,FGR,PCDHB7,FAT4,PLOD2,L3MBTL4,PRCP,ZNF214,PLXDC2,SLCO5A1,DLG2,TBC1D4,KIF1B,FILIP1 |
| 4.891e-04 | -7.62 | GO_MEMBRANE_ORGANIZATION | MSigDB lists | GO_MEMBRANE_ORGANIZATION | 841 | 112 | 17377 | 1707 |
DOC2A,FGF13,DOCK1,GRIK2,ATP8A1,LPCAT2,SYT12,VAMP8,PKP2,SYT14,NRXN1,PRKCA,SNX9,DOCK2,EPB41L3,SEC16B,PMAIP1,REEP1,RAP2A,RAB26,ZDHHC23,MAP7,LIN7A,TMED9,GULP1,PACSIN1,RPL26L1,CPE,KCNB2,RPS13,DPP10,GCA,ITGB7,GDAP1,KCNIP3,TMEM43,TGFA,ANK2,TRAM1L1,LRMP,BNIP3L,NLGN4X,RAB38,ATP1B1,ATP10D,SNCA,RANBP2,GSN,PRKCB,TNFRSF1A,AHNAK2,BBC3,MAGI2,TC2N,CHMP4C,HACE1,RPS20,TNIK,PLSCR4,SEC24D,PTPRD,TBC1D1,TSPAN15,ATP9A,LRP4,DHCR24,P2RY1,GAS6,USP30,TSPAN17,RPL13A,RPL34,BNIP1,RPS11,CACNB2,EHD3,PRKCD,PRELID1,PRKG2,LRP6,BNIP3,SH3PXD2B,STXBP1,RPS23,RPL26,VAV3,RAPGEF2,RPL21,PACSIN3,FERMT2,HIP1,ATP11A,SNAP25,SKAP1,BAIAP2,VPS37D,RPL12,MYADM,FAT4,RPL28,FCHO2,WDR19,HK2,RAB31,DLG2,RPL4,RPS12,TBC1D4,CDH2,FNBP1L,TESC,SFN |
| 4.941e-04 | -7.61 | response to lipid | biological process | GO:0033993 | 833 | 109 | 17256 | 1658 |
EPHA3,ACSL1,TRIM16,IL15,RBFOX2,LDLR,ASS1,LILRB1,NTRK3,CHUK,STAT5B,CYP26A1,RIDA,PLPP1,FBXO32,TGFBR3,KMO,DAB2IP,PDE4D,TLR4,SLIT2,PDGFRB,GLDC,GDAP1,FER,PTPRU,NR6A1,FZD4,ADCY1,YAP1,WNT11,ABCC2,CD40,SNCA,GNAI1,CXCL10,INSIG1,PTK7,EIF4EBP1,ITGA2,TNFRSF1A,PAM,HPGD,OXTR,TNFSF4,PPARGC1A,NR3C2,PSPH,HEY1,MEF2C,PRKAA2,GNG12,PLSCR4,TNFRSF10C,MLC1,BMP6,NEDD4,DDIT4,FOXP2,HMGCS1,EEF2,CA2,GATA2,BCHE,DSG2,STC2,SREBF1,LRP6,ADCY6,GRIP1,KLF9,ERRFI1,PCK2,AGL,STXBP1,GFI1,TNFRSF11A,ZFP36L2,ATP2B1,DUSP1,NOS3,FGFR4,MSTN,HNF4G,NR4A1,NUGGC,ESRRG,LITAF,FHL2,LRAT,DKK1,GPLD1,MAPKAPK2,CEBPB,MMP15,ID3,PMEPA1,ACER2,CTSV,XBP1,HOXD13,BMP4,CMPK2,TESC,SMYD3,PTGES,FOXA1,ABCG1,ATP1A3 |
| 4.966e-04 | -7.61 | stomach-carcinoma | COSMIC cancer mutations | stomach-carcinoma | 441 | 65 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PDGFRB,PRKACB,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,MAPK13,PIK3C2B,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,EPHB1,PKN1,IGF1R,ADCK1,PRKCD,PRKG1,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,MGMT,MAPKAPK2,TRIB3,FGR,PKN3,MAP2K6,AKT3,NEK11,PIP5KL1 |
| 4.970e-04 | -7.61 | SAM | interpro domains | IPR001660 | 92 | 20 | 18492 | 1811 |
EPHA3,ARAP2,INPPL1,SHANK2,PPFIBP2,PPFIA4,LCP2,EPHB1,PPP1R9A,L3MBTL4,PPFIBP1,KAZN,PPFIA2,CNKSR3,SAMD11,SFMBT1,EPHB6,SAMD13,MAP3K20,PHC1 |
| 4.971e-04 | -7.61 | calcium ion binding | molecular function | GO:0005509 | 698 | 95 | 17224 | 1680 |
PLA2G4A,DOC2A,CELSR3,LPCAT2,SYT12,LDLR,ITPR2,CANX,SYT14,NRXN1,DNER,PCLO,HMCN1,FSTL5,NCS1,PCDH7,EPDR1,PLS3,SCIN,TUBB4A,FKBP9,NELL2,UNC13B,PROS1,SLIT2,RASGRP1,GCA,KCNIP3,NECAB1,CSN2,CEMIP2,EFHC1,EFCC1,F12,ASPH,EML1,SNCA,GSN,ENPP1,CCBE1,PAM,BMP1,RCN3,TC2N,SPOCK3,PSPH,PCDH18,NECAB2,PLSCR4,CELSR1,CLGN,MCTP2,LRP4,SELL,CLSTN2,GAS6,HPCAL4,PRRG4,PPP2R3A,PCDHB14,EFEMP1,EHD3,DSG2,TBC1D9,FKBP14,TRPM4,CDH26,PCDH10,TBC1D8B,RAPGEF2,CACNA1E,EFHC2,DCHS1,VLDLR,EDEM3,PRRG1,RYR2,PLS1,C1R,PLCB1,MGMT,HEG1,GALNT3,PCDHB7,FAT4,FBN1,THBS4,FAT1,MATN2,CDH17,EGFL7,CDH2,TESC,TPT1,TLL2 |
| 5.010e-04 | -7.60 | sensory organ development | biological process | GO:0007423 | 508 | 72 | 17256 | 1658 |
MCOLN3,OTX1,GATA3,CEBPA,NTRK3,DDR1,GSDME,SKI,DLX6,CHRDL1,MYO3B,TBC1D32,LIN7A,MYH15,PDGFRB,CYP1B1,GPM6A,MEIS2,FZD4,NKX3-2,VIM,ACVR2B,ATOH1,ROR1,FGFR1,TSKU,SMAD3,INSIG1,PTK7,ATG5,NRP1,BCL11B,BMPR2,CELSR1,GABRB2,SLC25A27,LAMC3,EPHB1,FOXG1,BMP6,FOXP2,EFEMP1,IRX5,SLC7A11,GATA2,PDZD7,TFAP2A,LRP6,TSPAN12,SH3PXD2B,SPRY2,ATP2B1,B9D1,RAX,MSX1,KDM5B,DCHS1,MAFB,SMARCD3,PRDM1,SDK1,HOXA1,ZIC1,MAPKAPK2,FAT4,FBN1,WDR19,MYOM2,BMP4,NPHP1,SIX2,ATP2B4 |
| 5.022e-04 | -7.60 | GO_CALMODULIN_BINDING | MSigDB lists | GO_CALMODULIN_BINDING | 177 | 32 | 17377 | 1707 |
RGS16,MYO1D,SCN5A,PDE1B,AKAP5,MYO1B,ADD2,TJP1,KCNN2,MYH15,MARCKS,IQGAP3,FBXL2,MYO6,ATP2B1,SCN3A,NOS3,CTH,TRPM4,KCNQ3,MYO10,KCNH5,ADCY1,OBSCN,RYR2,SNTB1,PLCB1,MAPKAPK2,MAP2,RASGRF2,GEM,ATP2B4 |
| 5.022e-04 | -7.60 | V$HNF3_Q6 | MSigDB lists | V$HNF3_Q6 | 177 | 32 | 17377 | 1707 |
TYRO3,BCL11B,ID1,FGF13,CHCHD7,GRIK2,PLAG1,TJP1,CADM2,LCP2,NOVA1,ATXN7L1,KCTD15,FLRT3,SLC10A7,ZIC5,CHRDL1,SGK1,ERRFI1,GFRA1,GCNT2,MSTN,SLC39A8,NR4A1,PACSIN3,NFIA,ATOH1,SNAP25,PRDM1,GABARAPL1,GNAO1,MEF2C |
| 5.037e-04 | -7.59 | protein dimerization activity | molecular function | GO:0046983 | 1280 | 160 | 17224 | 1680 |
ACVR1,GRIK2,LILRB1,JCHAIN,GATA3,NPM1,CEBPA,CTBP2,STAT5B,CADM2,ABAT,SNX9,RBM11,IKZF2,SLC9A7,QPRT,TYMP,KCNN2,AADAT,GRHL1,HPS1,CFHR1,GSTM3,TLR4,ENO1,SLIT2,RASGRP1,GLDC,ATF4,NR6A1,LRRK2,BNIP3L,MEF2B,YAP1,CR2,AHRR,TRIM9,ENPP1,HPSE,ERN1,ADRB1,ERCC5,INPP5F,TPM1,NEUROG2,RRAGD,CHMP4C,CRYL1,MEF2C,TYRO3,CARS,CELSR1,ZHX3,JDP2,SLK,FBXO4,ADSSL1,GRPEL2,IL17D,SYCP2,ZBTB38,PRTFDC1,PDZD7,MYC,FLRT3,SREBF1,EBF4,LRP6,BNIP3,JAM2,HMGCR,MID2,CDH26,ATP5IF1,MSTN,TCF24,GSTM4,HOMER2,FASN,HIP1,MAFB,LHPP,TAF4B,PLCB1,KHDRBS2,SH3GL2,CSF1,HEYL,CDH2,TESC,NBL1,ID1,ADD2,CHUK,MAPK4,PPP1R9A,CBLN1,RIDA,ASNS,DAB2IP,KCNB2,GCA,GARS,FZD4,MVD,NLGN4X,ATF3,CBY1,ATOH1,JAM3,FGFR1,WARS,SMAD3,MSC,IKZF3,GYPC,GBP1,RBPMS2,ITGA2,WWTR1,MAP3K21,HPGD,SOHLH2,HGF,BMPR1A,MID1,PSPH,HEY1,TENM1,MXI1,GRB14,LRP4,CBS,P2RY1,TPD52L1,BMP6,FSD1,FOXP2,HMGCS1,BHLHA15,GHR,STC2,TFAP2A,PRKG2,RALGAPA2,GSTM2,NR4A1,RACK1,TLR6,EBF1,CEBPB,ID3,TERT,MPP7,NACC2,XBP1,DDIT3,BTRC,ABCG1,STOM |
| 5.052e-04 | -7.59 | lung-middle_lobe-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-middle_lobe-carcinoma-adenocarcinoma | 1388 | 172 | 17385 | 1698 |
FAM171B,DOC2A,CGN,ACSL1,PAGE1,LANCL3,TCP11L2,GRIK2,HEBP1,ALG1L,ITPR2,ABAT,HMCN1,SLCO3A1,EYA4,SLC9A7,RTN1,DLX6,PPFIA2,ANKFN1,ATRNL1,THSD1,CPE,OR2W3,SLIT2,GLDC,MARK1,DCDC1,ACVR1C,ANK2,KLHL4,DEPTOR,ENPP1,ATP7B,ERCC5,PIK3C2B,DLX2,UNC5B,MAGI2,NEUROG2,MLLT3,SCN5A,INPPL1,STXBP5L,PTPRD,ITPRIP,UBASH3B,STXBP6,SETBP1,LAMC3,FHOD3,DDIT4,IGF1R,FRY,BCHE,FRAS1,PDE10A,ZIC5,SRGAP1,SNX7,BOD1,PAK1,PCDH10,SLITRK2,COL4A4,PARD3B,ZNF605,TMTC4,PACSIN3,RYR2,PEX5L,ZBBX,SDK1,AMDHD1,CACHD1,GSTO2,ADAMTS3,PELI2,FAT1,PTPRN2,HOXD13,DISP2,SEMA3A,CDH2,FNBP1L,SIX2,AMPD1,DOCK9,CREB3L2,ZNF516,XYLT1,LRRCC1,COL18A1,PKP2,NTRK3,KIF21B,DOCK2,ZFYVE9,TIAM2,CCDC120,COL22A1,ASNS,SETDB2,KMO,ALDH1L1,ZNF521,MET,DNAH5,SCN3A,KCNB2,IGFBP3,INTU,COL6A2,TDRD3,THSD4,PANK1,CHRNA6,VIM,WNT11,PAGE5,DSP,MAGI3,SNCA,POPDC3,GBP1,LAMB1,RGS10,RCN3,KLF5,STON2,THOC3,CTNND2,PCDH18,PLSCR4,GRB14,ARHGEF11,GCAT,MCTP2,COL4A5,EPHB1,INPP1,BMP6,ARHGAP44,LRRC55,KCNJ4,TECPR1,GAS2L3,TSC22D1,SH3PXD2B,IQGAP3,SPRY2,FES,MED12L,TRPM4,MICAL2,LCA5,CRIM1,CACNA1E,RASA3,ATP11A,ZFPM2,ZIC1,PTPRC,DPY19L2,PCDHB7,FAT4,SLCO5A1,ZNF808,HK1,KIF21A,CACNA2D1,CRISPLD1 |
| 5.057e-04 | -7.59 | ovary-carcinoma-mucinous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mucinous_carcinoma | 458 | 67 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PDGFRB,PRKACB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,EPHB1,PKN1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,MAPKAPK2,TRIB3,FGR,PKN3,MAP2K6,AKT3,NEK11 |
| 5.060e-04 | -7.59 | clear_cell_carcinoma | COSMIC cancer mutations | clear_cell_carcinoma | 680 | 93 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,TCP11L2,CELSR3,GATA3,NDRG2,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,COL22A1,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,IL1RAP,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,NR6A1,LRRK2,NLGN4X,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,BCL11A,DYRK1B,SMAD3,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,PLD5,LIFR,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,ZHX3,PKN1,EPHB1,CHD5,IGF1R,ADCK1,PDZD7,PRKCD,SGK3,PRKG1,TFAP2A,SGK1,ALPK1,SYK,FES,PAK1,FGFR4,PCDH10,SLITRK2,MCF2L2,NUAK2,OBSCN,STRADB,PLS1,CDC42BPA,B4GALNT3,MAPKAPK2,TRIB3,FGR,PCDHB7,FAT4,TERT,PKN3,AKT3,MAP2K6,NEK11,FILIP1,AMPD1 |
| 5.062e-04 | -7.59 | GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN | MSigDB lists | GSE26495_PD1HIGH_VS_PD1LOW_CD8_TCELL_DN | 155 | 29 | 17377 | 1707 |
ATL1,KLF8,AGPAT4,DSTN,MCTP2,LRRCC1,NDRG2,CTBP2,F12,LDHD,HMCN1,HOPX,RGS17,FRY,PIK3AP1,OSBPL5,RUNDC3B,ADRB1,ACVR2A,TSPAN12,JAKMIP2,LIMCH1,SLCO4C1,NCAM1,TLR4,MAGI2,ATP6AP1L,PRKACB,LPP |
| 5.062e-04 | -7.59 | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP | 155 | 29 | 17377 | 1707 |
TMEM63C,SCAMP1,TNFSF13B,RYR2,PHACTR2,NRN1,CEBPA,BATF,CANX,PRKCA,ARRDC4,FAM162A,MGMT,GPLD1,SCIN,GABARAPL1,EPCAM,ATPAF2,ICA1,GRHL1,CSF1,PPFIBP1,MATN2,SFMBT1,SH3BGRL2,HGF,SLC22A15,THOC3,RRAGD |
| 5.062e-04 | -7.59 | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 155 | 29 | 17377 | 1707 |
PLA2G4A,QSOX1,DISC1,NBL1,PDK1,TUBA1A,ENO2,KDM5B,CHSY1,ARRDC4,LCP2,FAM162A,DDIT4,SMAD3,RNF141,SFXN1,SLC39A14,FGR,ALDOC,EIF4EBP1,PRELID2,EMILIN2,PRELID1,HK2,ATRNL1,P4HA1,BNIP3,ATG5,ENO1 |
| 5.108e-04 | -7.58 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 489 | 71 | 17377 | 1707 |
EPHA3,BTC,SORBS1,DOCK1,RBFOX2,STAT5B,NTRK3,LCP2,DDR1,ITGB3,DAB2IP,EPHB6,MET,PDGFRB,GAB2,TNK2,FER,FGF12,FGF17,PLEKHA1,ROR1,FRK,FGFR1,IRS2,NRG3,PTPRJ,NCKAP1L,EIF4EBP1,MAPK13,HGF,GRB10,NRP1,EFNB2,BMPR2,ESRP1,EPS8,ATP6V1E2,EPHB1,CD7,DOK5,DDIT4,EFEMP1,CHN1,IGF1R,FLRT3,GHR,GTF2F2,SREBF1,GFRA1,SYK,FES,PAK1,VEGFC,FGFR4,VAV3,BDNF,PXN,RHOQ,SH2D2A,CRIM1,RAPGEF2,ARID5B,EFNA3,PLCB1,BAIAP2,GPLD1,GALNT3,MAPKAPK2,FGR,CSF1,XBP1 |
| 5.138e-04 | -7.57 | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 1082 | 139 | 17377 | 1707 |
ATP8A1,GATA3,SNX9,RAC3,RND2,PPM1E,PMAIP1,HRK,TMED9,CTTN,PACSIN1,TLR4,SLIT2,PDGFRB,GPM6A,GCNT2,TGFA,DSTN,ELMOD1,FEZ1,GSN,GPRC5B,NCKAP1L,WIPF3,BBC3,ERCC5,OXTR,PPARGC1A,NRP1,TPM1,MAGI2,FN1,PTPRD,JDP2,SORBS3,PFN2,SPIRE1,EFEMP1,NUMBL,GATA2,FLRT3,SREBF1,BNIP3,LMAN2,RIMS2,EPB41L5,PAK1,BDNF,DISC1,RHOQ,SLITRK2,VLDLR,SLITRK5,HIP1,PLS1,PLCB1,FAM162A,CPEB1,BAIAP2,NEGR1,RPL28,CDH17,CDH2,FNBP1L,SFN,PLA2G4A,EPHA3,BTC,ID1,SORBS1,DNM3,AKAP5,C4A,GPR65,NTRK3,NRXN1,PPP1R9A,CBLN1,DOCK2,CD53,SCIN,UNC13B,BCL6,DAB2IP,PROS1,MARCKS,SNAI2,DPP10,FER,PHLDB2,MYLK3,EVL,PREX1,WNT11,PRKCQ,SYNJ2BP,AMIGO1,FGFR1,SNCA,BCL11A,SMAD3,PTPRJ,PEMT,PTK7,WWTR1,ITGA2,HGF,ATG5,COBL,CNTN1,BMPR2,ROBO2,LRP4,BIK,APBB1,CLSTN2,ARL2,SLX1B,GAS6,EPHB1,LRRN1,SCN1B,PRKCD,GTF2F2,SGK1,FIG4,SYK,FES,MSX1,RAPGEF2,TLR6,MAP1B,MYADM,MPP7,XBP1,BMP4,SHOX2,IL9R,STOM |
| 5.149e-04 | -7.57 | PROTEIN_KINASE_ATP | prosite domains | PS00107 | 378 | 61 | 12060 | 1278 |
EPHA3,PRKAA2,TYRO3,TNIK,LATS2,NEK10,ACVR1,DYRK3,BMPR2,PAK5,SLK,CHUK,NTRK3,MAPK4,GRK6,PRKCA,EPHB1,PKN1,STK24,MOK,SPEG,RPS6KA2,IGF1R,PRKCD,SGK3,PRKG1,MYO3B,PRKG2,SGK1,MET,SYK,PDGFRB,PRKACB,FES,PAK1,FGFR4,FER,TNK2,MYLK3,MARK1,ACVR1C,LRRK2,NUAK2,OBSCN,PRKCQ,CDC42BPA,SGK2,FRK,GRK3,FGFR1,DYRK1B,MAPKAPK2,FGR,PRKCB,PKN3,MAP2K6,PLK2,AKT3,MAP3K21,MAPK13,BMPR1A |
| 5.155e-04 | -7.57 | EGF-type_Asp/Asn_hydroxyl_site | interpro domains | IPR000152 | 99 | 21 | 18492 | 1811 |
CELSR1,LRP4,VLDLR,LDLR,C1R,GAS6,NRXN1,DNER,HMCN1,HEG1,EFEMP1,NELL2,FAT4,FBN1,CCBE1,FAT1,MATN2,BMP1,PROS1,SLIT2,TLL2 |
| 5.157e-04 | -7.57 | GUO_TARGETS_OF_IRS1_AND_IRS2 | MSigDB lists | GUO_TARGETS_OF_IRS1_AND_IRS2 | 92 | 20 | 17377 | 1707 |
VEGFC,MXI1,MVK,MVD,DHCR24,SLC7A2,SGK2,CYP51A1,CEBPB,MSMO1,PCBP4,XBP1,HPGD,SQLE,KLF9,PPARGC1A,DHCR7,GFRA1,LPP,HMGCR |
| 5.160e-04 | -7.57 | V$AREB6_02 | MSigDB lists | V$AREB6_02 | 238 | 40 | 17377 | 1707 |
SCN5A,SLC6A9,RBFOX2,PLAG1,OTX1,IL13RA1,CADM2,SLC12A6,FAM81A,IKZF2,NOVA1,DDR1,ARHGAP44,RTN1,LGI2,SPEG,HMGCS1,GPRIN1,BCL6,MAP7,NBEA,NKX2-1,USP2,TDRD3,KCNH5,EDEM3,PRDM1,KHDRBS2,GRIK4,SH3GL2,SH3RF1,MAP2K6,PGM2L1,DLG2,FNBP1L,SEMA3A,MAPK10,OCLN,FOXA1,AMPD1 |
| 5.165e-04 | -7.57 | RNA polymerase II regulatory region DNA binding | molecular function | GO:0001012 | 664 | 91 | 17224 | 1680 |
CREB3L2,TFCP2L1,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,IKZF3,HLF,BACH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,GLIS1,SMAD6,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 |
| 5.203e-04 | -7.56 | GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1601 | 196 | 17377 | 1707 |
ARHGAP26,DUSP8,GRIK2,LMCD1,GATA3,NDRG2,PRKCA,FAM13A,RAC3,NOS1AP,F3,ARHGEF10L,SIPA1L2,PMAIP1,RAP2A,RCAN3,TLR4,SLIT2,RASGRP1,PDGFRB,CYP1B1,GCNT2,WLS,TGFA,LRRK2,JPH1,DEPTOR,FGF17,PLEKHA1,ARHGEF26,GNAI1,INHBC,GPRC5B,HPSE,SH3RF1,PLK2,RASGRF2,ERN1,TNFRSF1A,ADRB1,BMP1,ARHGAP28,BBC3,INPP5F,DIRAS1,SPRY4,UNC5B,NRP1,MAGI2,RRAGD,PRKAA2,FN1,RHOBTB1,OPHN1,SORBS3,TNFRSF19,CHD5,IL18R1,DDIT4,MECOM,CHN1,IGF1R,RALGPS2,PIK3AP1,FLRT3,MYC,PDE10A,C1QL4,SRGAP1,FBXL2,ZNF385A,RNF152,HMGCR,FGFR4,PAK1,MID2,RHOQ,MSTN,SPATA13,DUSP9,OBSCN,WWC1,PEX5L,TAF4B,PLCB1,HERPUD1,MAPKAPK2,PELI2,CSF1,SH3BP4,INHBE,IQSEC2,CDH2,BTC,NEK10,ID1,AVPI1,RASAL2,IL15,RHOD,AKAP5,ARHGAP22,NTRK3,CHUK,PIBF1,TIAM2,TLR3,DACT1,CNKSR3,BCL6,DAB2IP,PDE4D,WWC2,SNAI2,CTH,IGFBP3,FZD4,PTPN6,PREX1,WNT11,ATF3,GSTO1,PRKCQ,SYNJ2BP,CD40,ASPH,FGFR1,MAGI3,IRS2,CXCL10,PTPRJ,PRKCB,GBP1,WFS1,PLEKHG1,DUSP19,TNFSF15,HGF,MAPK10,MID1,TNIK,FARP1,C1QTNF3,EDA2R,ARHGEF11,REL,FZD8,PSD3,P2RY1,GAS6,PKN1,NDFIP2,EPHB1,TPD52L1,BMP6,ARHGAP44,NEDD4,SYDE2,CHN2,MCF2L,RASD2,PRKCD,GHR,RALGAPA2,IQGAP3,ERRFI1,TNFRSF11A,SPRY2,SYK,DUSP1,VAV3,MSX1,ARAP2,GSTM2,MCF2L2,RAPGEF2,PTPN13,CYTH3,LITAF,RASA3,ARHGAP32,TLR6,GPR37,TRIB3,FGR,MYADM,NACC2,MAP2K6,XBP1,UACA,LRRK1,BMP4,DDIT3,BTRC,ATP2B4,TPT1 |
| 5.210e-04 | -7.56 | GO_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | 42 | 12 | 17377 | 1707 |
SMAD3,EFEMP1,RUNX2,NKX3-2,CHADL,BMP4,SHOX2,BMP6,SNAI2,SIX2,TRPS1,SCIN |
| 5.210e-04 | -7.56 | HUANG_FOXA2_TARGETS_UP | MSigDB lists | HUANG_FOXA2_TARGETS_UP | 42 | 12 | 17377 | 1707 |
KCNV1,ENPP1,ASNS,FN1,SLC7A11,MAP2,HPGD,CADPS2,PLEKHA1,CHAC1,PCK2,LAMP3 |
| 5.210e-04 | -7.56 | GO_EPITHELIAL_CELL_MORPHOGENESIS | MSigDB lists | GO_EPITHELIAL_CELL_MORPHOGENESIS | 42 | 12 | 17377 | 1707 |
BCL11B,EPB41L5,ID1,ST14,GATA3,COL18A1,BMP4,MET,PALLD,SIX2,ARHGEF26,HEG1 |
| 5.215e-04 | -7.56 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | 523 | 75 | 17377 | 1707 |
GALNT6,GALNT12,PLEKHA5,ARHGAP22,MCOLN3,TNFAIP8L2,FAM102B,NHP2,PRKCA,NCS1,F3,RTN1,PMAIP1,ITGB3,RAP2A,SERINC2,STEAP3,MET,IL1RAP,RASGRP1,LAMP3,SLC3A2,CD55,TGFA,ACO1,ATP1B1,CD40,DOCK5,ASPH,BATF3,SLC7A1,GSN,ZNF697,GPR160,P4HA2,CCNA1,MAPK13,NRP1,LPP,LONRF1,TNIK,FN1,REL,CD276,WDFY4,NDFIP2,PHLDA2,HOPX,KIAA1671,SLC7A11,TSC22D1,MARCH3,FAR2,SMAD6,TNFRSF11A,FMNL2,PDLIM7,MICAL2,RHOQ,PNP,CRIM1,FOXN3,HOMER2,MEI1,HIP1,AK4,PHACTR2,FNDC3A,FAM162A,MFSD2A,CSF1,MAP2K6,RAB31,RAI14,TBC1D4 |
| 5.226e-04 | -7.56 | CHO_NR4A1_TARGETS | MSigDB lists | CHO_NR4A1_TARGETS | 31 | 10 | 17377 | 1707 |
SLC3A2,ASNS,ATF4,INSIG1,ATF3,TNS1,HERPUD1,GRPEL2,DDIT3,CTH |
| 5.226e-04 | -7.56 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | 31 | 10 | 17377 | 1707 |
SLC7A1,SLC3A2,SLC7A11,SLC36A1,SLC7A5,SLC6A15,SLC7A2,SLC1A5,SLC16A10,SLC43A1 |
| 5.280e-04 | -7.55 | HALLMARK_ESTROGEN_RESPONSE_LATE | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_LATE | 200 | 35 | 17377 | 1707 |
NBL1,FARP1,ST14,UGDH,BLVRB,ASS1,OVOL2,TPD52L1,RPS6KA2,CA2,UNC13B,OPN3,SGK1,TSPAN13,SNX10,CPE,PERP,SLC27A2,PTPN6,HOMER2,PRKAR2B,BATF,FRK,ISG20,PDLIM3,WFS1,XBP1,CCNA1,SLC7A5,RAB31,MAPK13,DHCR7,PTGES,ATP2B4,SFN |
| 5.284e-04 | -7.55 | endothelial cell differentiation | biological process | GO:0045446 | 74 | 17 | 17256 | 1658 |
ACVR1,ID1,BMPR2,RAPGEF2,COL18A1,TJP1,ACVR2B,ARHGEF26,HEG1,MYADM,MARVELD2,PTPRS,GSTM3,PDE4D,NRP1,MET,HEY1 |
| 5.284e-04 | -7.55 | FLRT1 (fibronectin leucine rich transmembrane protein 1) | protein interactions | 23769 | 16 | 7 | 17029 | 1718 |
TCAF2,RADIL,ADGRL2,FLRT3,FGFR1,ADGRL1,PCDH7 |
| 5.303e-04 | -7.54 | cerebral cortex development | biological process | GO:0021987 | 108 | 22 | 17256 | 1658 |
GNG12,FGF13,EFHC1,ATOH1,FOXG1,PLCB1,FOXP2,FAT4,EOMES,TACC2,LHX6,LAMB1,LRP6,PTPRS,BNIP3,DAB2IP,NRP1,SEMA3A,CDH2,SLIT2,POU3F3,NKX2-1 |
| 5.303e-04 | -7.54 | establishment of cell polarity | biological process | GO:0030010 | 108 | 22 | 17256 | 1658 |
PAK1,UST,AMOTL1,MARK1,FGF13,ARHGEF11,PARD3B,CYTH3,OPHN1,FEZ1,WWC1,GPSM2,EPHB1,JAM3,DOCK2,MAP1B,DOCK7,MPP7,MAP2,PTK7,RAP2A,SPRY2 |
| 5.304e-04 | -7.54 | Guanylate_kin | pfam domains | PF00625 | 26 | 9 | 17054 | 1666 |
MPP7,MPP1,CACNB2,MPP2,DLG2,TJP1,CACNB4,MAGI2,MAGI3 |
| 5.304e-04 | -7.54 | GSE30083_SP2_VS_SP4_THYMOCYTE_UP | MSigDB lists | GSE30083_SP2_VS_SP4_THYMOCYTE_UP | 185 | 33 | 17377 | 1707 |
EXPH5,TMEM63C,ATP9A,ESRP1,MCOLN3,YPEL2,LAMC3,TDRKH,NEDD4,NEO1,MCU,SCN1B,TACC2,TSC22D1,CTTN,EPHB6,MORN4,FER,TNK2,VNN2,TUBA1A,ANK2,FGF12,AMIGO1,GSN,TMEM237,RBPMS2,THSD7B,MPP2,LAPTM4B,SLC16A10,PCSK5,ACSM3 |
| 5.304e-04 | -7.54 | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_UP | 185 | 33 | 17377 | 1707 |
LONRF1,WASF3,ZSWIM5,ANKRD13D,IL15,NLRP14,NKAIN2,NDRG2,KCTD12,CADM2,SPATS2L,KCNC4,MCOLN2,CNTN4,PDZD8,DSG2,ITGB3,CPXM2,IPCEF1,DUSP1,PNMA2,GCA,SMAD9,SH2D2A,CACNA1E,ZDHHC15,FERMT2,PRICKLE1,PRDM1,ARRDC4,CACHD1,PLEKHH2,PELI2 |
| 5.333e-04 | -7.54 | EGF-like_Ca-bd_dom | interpro domains | IPR001881 | 120 | 24 | 18492 | 1811 |
CELSR1,CELSR3,LRP4,VLDLR,LDLR,C1R,F12,GAS6,DNER,HMCN1,HEG1,EFEMP1,NELL2,FAT4,FBN1,FAT1,CCBE1,THBS4,MATN2,BMP1,EGFL7,PROS1,SLIT2,TLL2 |
| 5.341e-04 | -7.54 | transporter complex | cellular component | GO:1990351 | 329 | 50 | 18223 | 1724 |
KCNV1,SCN5A,CACNG3,GRIK2,GABRB2,SCN8A,GABRG2,GABRR2,KCNC4,CACNB4,ABHD6,NOS1AP,MCU,KCNJ4,LRRC55,KCNAB1,CHRNA5,SCN1B,CACNB2,KCNMB3,KCNS3,PDE4D,CTTN,SCN2A,HSPA2,KCNB2,SCN3A,TRPM4,DPP10,KCNIP3,KCNQ3,LRRC8B,CACNA1E,SHANK2,CHRNA6,TTYH2,RYR2,CATSPERE,KCND3,ATP1B1,SNAP25,AMIGO1,HERPUD1,GRIK4,KCNMB4,KCNG1,GRIN2D,DLG2,CACNA2D1,ATP1A3 |
| 5.349e-04 | -7.53 | V$ATF1_Q6 | MSigDB lists | V$ATF1_Q6 | 223 | 38 | 17377 | 1707 |
CREB3L2,DYRK3,ID1,LMCD1,GABRG2,SEZ6L2,NRXN1,NOVA1,EEF2,PDZD8,NOVA2,TMEM86A,STC2,KCNMB3,KLF9,PDE4D,RNF148,SMAD6,GLI1,PAK1,GPR176,NR6A1,PTPRU,ESRRG,BNIP3L,SNAP25,PLEKHA1,RNF44,MBNL2,CD37,ADAMTS3,GNB4,DLG2,RPL4,GEM,MAPK10,HOXB9,DDIT3 |
| 5.381e-04 | -7.53 | GO_FOREBRAIN_CELL_MIGRATION | MSigDB lists | GO_FOREBRAIN_CELL_MIGRATION | 60 | 15 | 17377 | 1707 |
TYRO3,DISC1,NRG3,FGF13,LHX6,LAMB1,LRRK2,EFHC1,DAB2IP,NRP1,SEMA3A,SLIT2,FGFR1,POU3F3,NKX2-1 |
| 5.381e-04 | -7.53 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP | 60 | 15 | 17377 | 1707 |
VAV3,GPM6A,PLSCR4,SCAMP1,CFHR1,CLSTN2,SGK1,CALCRL,SEMA3C,PRKAR2B,LIFR,SLIT2,PERP,TPK1,PCDH7 |
| 5.394e-04 | -7.53 | embryo development | biological process | GO:0009790 | 889 | 115 | 17256 | 1658 |
THOC5,ACVR1,ST14,RECK,UGDH,OTX1,PLXNA2,GATA3,CEBPA,KIAA1217,SP8,SKI,SETDB2,EOMES,DACT1,DLX6,ITGB3,MYO3B,TBC1D32,ACVR2A,PRKACB,GLI1,FZD1,INTU,NKX3-2,WLS,YAP1,SATB2,WNT11,ACVR2B,ATOH1,RARRES2,FGFR1,SMAD3,INSIG1,PTK7,RBPMS2,APELA,ITGA2,LAMB1,SEMA3C,BMPR1A,DISP1,DLX2,NRP1,TPM1,TANC2,VASH2,APBA2,HOXB9,COBL,PCSK5,HEY1,MEF2C,STOX2,RUNX2,FN1,BMPR2,CELSR1,SEC24D,LRP4,OVOL2,APBA1,FOXG1,PHGDH,PGAP1,PPP2R3A,HOPX,EFEMP1,IRX5,PDZD7,GATA2,MGAT1,FLRT3,FRAS1,TFAP2A,LRP6,DYNC2H1,YBX3,SMAD6,SPRY2,PCSK6,DUSP1,NOS3,VEGFC,EPB41L5,B9D1,MICAL2,MSX1,DCHS1,PRICKLE1,MAFB,RYR2,PRDM1,RACK1,ZFPM2,HOXA1,ZIC1,HEG1,DKK1,MMP15,CEBPB,ID3,FBN1,CECR2,WDR19,PCGF2,HOXD13,BMP4,SHOX2,SEMA3A,MMP16,MAP3K20,FOXA1,SIX2 |
| 5.408e-04 | -7.52 | GK/Ca_channel_bsu | interpro domains | IPR008145 | 26 | 9 | 18492 | 1811 |
MPP7,MPP1,CACNB2,MPP2,TJP1,DLG2,CACNB4,MAGI2,MAGI3 |
| 5.447e-04 | -7.52 | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_UP | MSigDB lists | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_UP | 163 | 30 | 17377 | 1707 |
RGS16,ARAP2,KCNIP3,TTC39B,PNP,CLGN,SLK,FAM84A,XYLT1,SETBP1,HERC5,COBLL1,PRDM1,CHSY1,GABARAPL1,HOPX,TRPS1,ISG20,GALNT3,CXCL10,MYADM,EOMES,PMAIP1,GPR160,RAP2A,PGM2L1,SERPINI1,GEM,TNFSF4,SNX10 |
| 5.447e-04 | -7.52 | GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN | MSigDB lists | GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN | 163 | 30 | 17377 | 1707 |
BCL11B,TMC7,FER,SORBS1,ATF4,COL4A3,IGFBP6,NR4A1,THSD4,LPCAT2,PTPN13,MYO1B,FHL2,MORC4,GATA3,CALCRL,KCTD12,PRKCQ,SKAP1,IRS2,HLF,RPL12,MYADM,EEF2,PLOD2,ISM1,INPP4B,MOXD1,ZFP36L2,DUSP1 |
| 5.458e-04 | -7.51 | inorganic cation transmembrane transport | biological process | GO:0098662 | 544 | 76 | 17256 | 1658 |
CACNG3,MCOLN3,ITPR2,SLC2A13,CACNB4,SLC9A7,NCS1,KCNAB1,KCNN2,KCNS3,TRPC1,CNNM2,SLC2A12,STEAP3,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,SLC9C1,SLC39A8,KCNH5,ATOX1,SLC25A28,KCND3,ATP1B1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,SCN5A,SCN8A,ATP6V1E2,GAS6,SLC1A3,SLC12A6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,BHLHA15,CACNB2,KCNMB3,NIPAL2,FAM155A,ATP2B1,NDUFA4L2,TRPM4,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RASA3,RYR2,STEAP1,PTPRC,TMCO3,KCNK15,SLC2A6,GRIN2D,TRPC3,CACNA2D1,ATP2B4,DDIT3,ATP1A3 |
| 5.459e-04 | -7.51 | TAVOR_CEBPA_TARGETS_UP | MSigDB lists | TAVOR_CEBPA_TARGETS_UP | 48 | 13 | 17377 | 1707 |
PTPRC,ACSL1,CA2,GBP1,BIK,LITAF,RAB31,KIAA0513,SERPINI1,KLF5,FIG4,CD7,MLC1 |
| 5.459e-04 | -7.51 | TSUNODA_CISPLATIN_RESISTANCE_DN | MSigDB lists | TSUNODA_CISPLATIN_RESISTANCE_DN | 48 | 13 | 17377 | 1707 |
SLC3A2,ID1,FN1,SLC27A2,FBN1,MAGEA3,SLC7A5,TSC22D1,SGK1,ASS1,MAGEA6,PTGES,C4BPB |
| 5.472e-04 | -7.51 | inorganic cation transmembrane transporter activity | molecular function | GO:0022890 | 596 | 83 | 17224 | 1680 |
CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,CACNB4,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,SLC22A18,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,SLC9C1,SLC39A8,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,KCND3,ATP1B1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,TMEM63C,SCN5A,SLC6A9,SCN8A,ATP6V1E2,GAS6,SLC1A3,SLC12A6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,CACNB2,KCNMB3,SLC6A15,NIPAL2,FAM155A,SLC45A3,ATP2B1,NDUFA4L2,TRPM4,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RASA3,RYR2,GRIK4,TMCO3,KCNK15,SLC2A6,GRIN2D,TRPC3,CACNA2D1,ATP2B4,ATP1A3 |
| 5.495e-04 | -7.51 | V$SP1_Q2_01 | MSigDB lists | V$SP1_Q2_01 | 231 | 39 | 17377 | 1707 |
BCL11B,FLVCR2,BCL6B,ENAH,RNF24,NTRK3,FAM117B,CADM2,CBLN1,PPP2R3A,FSTL5,MECOM,NUMBL,KCNN2,ADCK1,PPFIA2,RAB26,SCARF2,BCL6,LOXL4,GFRA1,NKX2-1,GLI1,PAK1,MN1,NDUFA4L2,PTCH2,BDNF,SESN2,FGF12,NFE2L1,SLITRK5,CTTNBP2NL,PTPRJ,PCGF2,ADRB1,TIGD4,NXPH4,CDH2 |
| 5.507e-04 | -7.50 | positive regulation of hydrolase activity | biological process | GO:0051345 | 755 | 100 | 17256 | 1658 |
ARHGAP26,RASAL2,DOCK1,GPR65,ARHGAP22,RGS20,NTRK3,FAM13A,SNX9,TBC1D30,DOCK2,TIAM2,F3,TBC1D19,ADPRHL1,SIPA1L2,PMAIP1,DAB2IP,PCOLCE2,HSPA2,PERP,DOCK8,RASGRP1,PDGFRB,TBC1D8,COL4A3,ACVR1C,LRRK2,ELMOD1,PREX1,WNT11,ATP1B1,CD40,ASPH,TBC1D16,FGFR1,SNCA,SMAD3,RANBP2,GSN,ARHGAP21,BEX3,NCKAP1L,ITGA2,ERN1,ADRB1,RGS10,ARHGAP28,BBC3,TNFSF15,TPM1,NRP1,MAGI2,MEF2C,RGS16,LPAR2,FN1,STXBP5L,ARHGEF11,TBC1D1,ITGA6,OPHN1,RGS7,DYNC1I1,PFN2,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,MYC,PRKCD,PRELID1,SRGAP1,RALGAPA2,ERRFI1,TBC1D9,RIN2,VAV3,ARAP2,TBC1D8B,RAPGEF2,ASAP3,EFNA3,RYR2,RASA3,HIP1,AGAP2,ARHGAP32,RACK1,PLCB1,FAM162A,GPLD1,TBC1D2,DOCK7,ADGRB3,ACER2,GNAO1,TBC1D4,DOCK9 |
| 5.512e-04 | -7.50 | GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 270 | 44 | 17377 | 1707 |
ARHGAP26,FARP1,RASAL2,ARHGEF11,RHOBTB1,RHOD,ARHGAP22,OPHN1,PSD3,FAM13A,RAC3,ARHGAP44,TIAM2,SYDE2,ARHGEF10L,CHN1,SIPA1L2,CHN2,RALGPS2,MCF2L,SRGAP1,BCL6,RALGAPA2,DAB2IP,SLIT2,SPRY2,RASGRP1,VAV3,ARAP2,RHOQ,MCF2L2,CYTH3,PREX1,SPATA13,OBSCN,RASA3,ARHGAP32,ARHGEF26,CSF1,RASGRF2,PLEKHG1,ARHGAP28,IQSEC2,CDH2 |
| 5.537e-04 | -7.50 | plasma membrane protein complex | cellular component | GO:0098797 | 570 | 78 | 18223 | 1724 |
ACVR1,SORBS1,CACNG3,GRIK2,CHUK,IL13RA1,PRKCA,CACNB4,ABHD6,NOS1AP,TGFBR3,KCNAB1,CHRNA5,ITGB3,KCNS3,LIN7A,ACVR2A,CTTN,PDE4D,SCN2A,HSPA2,SCN3A,KCNB2,DPP10,TNK2,ITGB7,KCNIP3,ACVR1C,PTPN6,GJB2,SHANK2,CHRNA6,AMIGO1,KCND3,ATP1B1,CD40,GNAI1,GJC1,KCNMB4,KCNG1,ITGA2,BMPR1A,KCNV1,GNG12,SCN5A,ITGA6,FZD8,SCN8A,LRP4,RGS7,KCNC4,NEO1,KCNJ4,LRRC55,IGF1R,SCN1B,CACNB2,KCNMB3,LRP6,SYK,CDH26,KCNQ3,CACNA1E,CALCRL,HIP1,CATSPERE,SNAP25,SNTB1,SKAP1,TLR6,GRIK4,MPP7,GNAO1,GRIN2D,DLG2,CDH2,CACNA2D1,ATP1A3 |
| 5.549e-04 | -7.50 | Photodynamic therapy-induced unfolded protein response | WikiPathways | WP3613 | 29 | 10 | 5312 | 569 |
TRIB3,ATF4,ASNS,DNAJC3,ERN1,XBP1,BBC3,ATF3,DDIT3,WARS |
| 5.557e-04 | -7.50 | RODRIGUES_DCC_TARGETS_DN | MSigDB lists | RODRIGUES_DCC_TARGETS_DN | 120 | 24 | 17377 | 1707 |
TRIM2,RUNX2,KDM5B,MYO10,FOXN3,BACE1,EPS8,BIK,CYP4V2,LITAF,ABAT,SNTB1,GSN,GPR160,BCL6,NDUFB8,LIMCH1,NRP1,VWA5A,SEPT3,MAST4,MID1,RASGRP1,CSRP2 |
| 5.558e-04 | -7.50 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN | 178 | 32 | 17377 | 1707 |
ACSL1,ALOX5AP,GALNT6,ITGA6,XYLT1,CEBPA,LCP2,KBTBD11,SLCO3A1,CYP51A1,GATA2,MGAT1,EHD3,PRKCD,TSC22D1,SLCO4C1,ZFP36L2,CKAP4,CYP1B1,FADS1,MICAL2,CD55,ABCC4,SLC27A2,FHL2,RNF125,CSF1,CCNA1,SLC7A5,TPM1,IL9R,TESC |
| 5.558e-04 | -7.50 | GSE22886_TH1_VS_TH2_12H_ACT_DN | MSigDB lists | GSE22886_TH1_VS_TH2_12H_ACT_DN | 178 | 32 | 17377 | 1707 |
ARHGAP26,PLA2G4A,UGT8,MRC2,TBC1D8B,ESRRG,SLC39A8,HOMER2,RNF125,HIP1,DDR1,MBNL2,PCLO,NIPSNAP3B,CTNNA2,HERPUD1,NOS1AP,NEO1,GALNT3,SLC39A14,CXCL10,IKZF3,HPSE,PDE10A,GHR,INPP4B,RNF130,SUSD4,SNX10,MYT1,POU3F3,SNAI2 |
| 5.563e-04 | -7.49 | GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 765 | 103 | 17377 | 1707 |
DNM3,ID1,FGF13,GATA3,LILRB1,PKP2,STAT5B,NTRK3,SEMA6A,TBC1D30,SKI,TLR3,ITGB3,BCL6,DAB2IP,WWC2,TLR4,SLIT2,SEMA6C,PRKACB,SNAI2,NKX2-1,PRAME,PHLDB2,MEIS2,COL4A3,CSN2,ACVR1C,DCC,NKX3-2,YAP1,VIM,WNT11,SYNJ2BP,SAV1,FGFR1,BCL11A,SMAD3,ENPP1,CXCL10,NRG3,INSIG1,GBP1,PLK2,WWTR1,ADRB1,SEMA3C,INPP5F,DLX2,BMPR1A,NRP1,TNFSF4,PPARGC1A,SEMA6B,ROBO2,UBASH3B,JDP2,LRP4,CHADL,OVOL2,GAS6,SPINK5,HOPX,NKX6-1,EFEMP1,CNTN4,SEMA4F,GATA2,ABCA5,BHLHA15,MYC,C1QL4,STC2,KIAA0319,ADCY6,BNIP3,FIG4,GFI1,ZFP36L2,GPR161,TRPM4,MSX1,USP2,MSTN,RAPGEF2,MAFB,WWC1,PRICKLE1,ZFPM2,DKK1,TRIB3,ID3,TERT,THBS4,XBP1,SFMBT1,BMP4,SEMA3A,FOXA1,DDIT3,SIX2,ABCG1,TLL2 |
| 5.565e-04 | -7.49 | GO_PHOSPHATIDYLINOSITOL_BINDING | MSigDB lists | GO_PHOSPHATIDYLINOSITOL_BINDING | 193 | 34 | 17377 | 1707 |
PLEKHA5,STXBP6,MYO1B,ITPR2,APBA1,SNX9,PFN2,ZFYVE9,SCIN,TECPR1,ZFYVE28,MCF2L,SGK3,DAB2IP,SH3PXD2B,CLVS2,SNX10,FES,GAB2,SNX7,MARK1,ARAP2,MYO10,PLEKHA8,CYTH3,FERMT2,HIP1,ARHGAP32,PLEKHA1,PLCB1,FCHO2,OSBPL5,PIK3C2B,PLD1 |
| 5.565e-04 | -7.49 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_UP | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_UP | 193 | 34 | 17377 | 1707 |
FGF13,CHCHD7,LDLR,MCTP2,GABRR2,OTUD1,CA2,RALGPS2,ZFYVE28,RUNDC3B,SGK3,ADCY6,ST8SIA1,TSPAN9,CAND2,ZNF629,ALDH2,MYO10,PFKFB2,CAP2,NPM3,KLHL4,PRRG1,ABCC2,NPC2,TBC1D16,IFT81,INSIG1,GPRC5B,RASGRF2,C1orf21,RNF130,TESC,AMPD1 |
| 5.565e-04 | -7.49 | GO_RESPIRATORY_SYSTEM_DEVELOPMENT | MSigDB lists | GO_RESPIRATORY_SYSTEM_DEVELOPMENT | 193 | 34 | 17377 | 1707 |
ID1,CELSR1,BMPR2,ASS1,CEBPA,GPSM2,HOPX,SKI,FOXP2,KCNAB1,SREBF1,LRP6,ERRFI1,SPRY2,NKX2-1,FZD1,GLI1,NOS3,YAP1,WNT11,ACVR2B,ZFPM2,SAV1,FGFR1,HEG1,MSC,EIF4EBP1,PTK7,DISP1,BMP4,BMPR1A,NKX2-8,DHCR7,FOXA1 |
| 5.623e-04 | -7.48 | V$MYOGENIN_Q6 | MSigDB lists | V$MYOGENIN_Q6 | 239 | 40 | 17377 | 1707 |
SV2B,NBL1,BMPR2,RHOD,ZCCHC24,ITGA6,XYLT1,TJP1,PKN1,ZFYVE9,CYP26A1,DDIT4,TUBB4A,MAP1A,BNIP3,LOXL4,GFRA1,POU3F3,IGSF3,RNF152,EPB41L5,NDUFA4L2,KCNIP3,COL4A3,COL4A4,PARD3B,CRIP2,WDR25,ATP1B1,NEGR1,DDAH1,FGR,PTPRJ,KIAA0355,HEYL,UACA,TUFT1,DBP,DNHD1,DOCK9 |
| 5.627e-04 | -7.48 | synapse assembly | biological process | GO:0007416 | 81 | 18 | 17256 | 1658 |
BDNF,GPM6A,FARP1,DNM3,PTPRD,LRP4,SHANK2,NLGN4X,SDK1,NRXN1,DNER,PCLO,PCDHB14,PCDHB7,FLRT3,CDH2,MAGI2,FZD1 |
| 5.628e-04 | -7.48 | vesicle | cellular component | GO:0031982 | 3810 | 414 | 18223 | 1724 |
DOC2A,PLBD2,PRSS12,ATP8A1,DNAJC3,LDLR,VAMP8,MCOLN3,PRKCA,SNX9,AARS,RAC3,SLC9A7,STK24,NCS1,PCDH7,TXNDC5,TGFBR3,ZFYVE28,PPFIA2,RAP2A,RAB26,SERINC2,GSTM3,TMED9,PACSIN1,CPE,GGACT,WLS,TGFA,ALDH1L2,DSTN,LRRK2,DNAJC6,LRMP,PRKAR2B,F12,GNAI1,ENPP6,NCKAP1L,ATP7B,ENTPD7,ALDOA,BDH2,ADRB1,BMP1,SEMA3C,INPP5F,SERPINI1,NRP1,DNHD1,CRYL1,GNG12,PTPRD,SCN8A,SLK,GABRB2,CYP2J2,APBA1,DYNC1I1,MCOLN2,GBGT1,BACE2,SREBF1,GRIP1,MPDZ,CADPS2,LMAN2,LOXL4,DENND1C,MOXD1,AGL,STXBP1,GFRA1,RIMS2,GPR161,BDNF,RPL26,QSOX1,PNP,FASN,PACSIN3,RYR2,HIP1,CALCRL,PLS1,C1R,NPC2,SNAP25,CDC42BPA,RABAC1,ARRDC4,PLCB1,CLN5,TMEM74,VPS37D,GSTO2,SH3GL2,RPL28,PMEPA1,ADAMTS3,THBS4,LAPTM4B,PLA2G4A,FRMPD3,EPHA3,AMOTL1,PCSK1N,DNM3,SCAMP1,RNF144A,RHOD,C4A,MYO1B,MSR1,RGS20,ADD2,NRXN1,DDR1,ZFYVE9,TIAM2,GPR15,CCDC120,PLPP1,ERG28,TLR3,ALDOC,STARD4,ALDH1L1,DAB2IP,MARCKS,RAB27B,RPL26L1,SYNGR3,SNX10,GATM,GARS,COL6A2,GAPDH,FZD4,PANK1,ADCY1,RAB38,ATP1B1,DSP,TBC1D16,FGFR1,GABARAPL1,SNCA,PATJ,ENTPD1,ARHGAP21,PRKCB,LAMB1,PAM,HPGD,ATG5,CTTNBP2,STON2,RPS20,WASF3,SERINC5,MYO1D,ANKRD13D,ANKRD13B,C1QTNF3,ROBO2,GLIPR1L1,ATP9A,BACE1,EPS8,GAS6,CREB5,PKN1,EPHB1,NDFIP2,SELENOP,NEDD4,RGS17,MGAT1,GPR155,SGK3,MORN2,DYNC2H1,FIG4,MYO6,SMPDL3A,FES,VEGFC,SLC40A1,ALDH2,GSTM2,RAB6B,RAPGEF2,PTPN13,ATP11A,RACK1,GPLD1,GALNT3,PTPRC,FGR,RPL12,PLOD2,CRISPLD1,DDIT3,OCLN,TPT1,ATP1A3,EXPH5,CACNG3,HEBP1,SYT12,UGDH,ASS1,NDRG2,JCHAIN,ITPR2,DNER,HMCN1,QPRT,ADPRHL1,EPCAM,TUBB4A,RND2,CPNE2,TM9SF2,SEC16B,CPVL,HPS1,MARVELD2,ITGB3,LIN7A,MYRIP,ENO1,TLR4,NEB,SLIT2,PDGFRB,PRKACB,LAMP3,ITGB7,TNK2,GPM6A,SLC3A2,CD55,ABCC4,CEMIP2,ANK2,CAPN5,CR2,COTL1,PLEKHA1,SPNS1,TRIM9,GSN,AK1,TMEM150B,GPRC5B,HPSE,GNB4,AHNAK2,PIK3C2B,APBA2,MAGI2,MLLT3,RRAGD,CHMP4C,PCSK5,SV2B,LGALS3,FN1,RHOBTB1,SEC24D,HID1,ATP6V1E2,PFN2,MLC1,SPINK5,PHGDH,SPIRE1,EFEMP1,CA2,SLC30A4,EEF2,ABCA5,RPS11,LRP6,SLCO4C1,CKAP4,SNX7,NOS3,FGFR4,MID2,RHOQ,SLC27A2,PDE8A,SLC46A3,STEAP1,BAIAP2,TBC1D2,MAPKAPK2,FCHO2,FAT1,RAB31,SH3BP4,PTPRN2,PLD1,FNBP1L,MME,SFN,DMXL2,PRKN,EML5,CFH,IL15,COL18A1,COBLL1,KIF21B,CANX,DOCK2,PCLO,SCIN,CD53,RIDA,UNC13B,STEAP3,PROS1,CLVS2,HSPA2,CTH,RPS13,ANTXR2,GCA,TMEM67,EVL,TUBA1A,PTPN6,THSD4,ACO1,GSTO1,VIM,RARRES2,CD40,FRK,WARS,PTPRJ,GBP1,PTPRS,HGF,SEPT5,LIFR,CNTN1,ARFGEF3,MAN2B2,TNIK,LPAR2,ENO2,PRSS16,GRB14,TSPAN15,RUSC2,ARL15,BLVRB,GABRG2,SELL,BMP6,ARHGAP44,RPL34,RAB11FIP5,NKX6-1,KCNJ4,TECPR1,PRKCD,DSG2,EHD3,KIAA0319,ACTA2,TRIM3,MARCH3,ESD,RRAS2,SYK,ATP2B1,CES3,MOB1B,RAB3B,SYBU,LITAF,GRID1,MARS,AGAP2,PHACTR2,ARHGAP32,FNDC3A,TLR6,LRAT,SMPDL3B,DKK1,CD37,DDAH1,ICA1,FAT4,RND3,PRCP,CTSV,SLC7A5,UACA,RPL4,SLC1A5,TBC1D4,KIF1B,CACNA2D1,ABCG1,STOM |
| 5.644e-04 | -7.48 | ASX_HYDROXYL | prosite domains | PS00010 | 99 | 22 | 12060 | 1278 |
CELSR1,CELSR3,LRP4,VLDLR,LDLR,C1R,GAS6,NRXN1,DNER,HMCN1,HEG1,EFEMP1,NELL2,FAT4,FBN1,FAT1,CCBE1,MATN2,BMP1,EGFL7,PROS1,SLIT2 |
| 5.646e-04 | -7.48 | GO_CELL_SUBSTRATE_ADHESION | MSigDB lists | GO_CELL_SUBSTRATE_ADHESION | 156 | 29 | 17377 | 1707 |
TYRO3,EPB41L5,FER,ITGB7,SORBS1,PXN,ID1,FN1,FZD4,BVES,RHOD,ITGA6,FERMT2,SORBS3,GAS6,EPHB1,DDR1,PEAK1,RADIL,JAM3,EPDR1,HPSE,PPFIA2,ITGB3,LAMB1,ITGA2,MARCKS,CTTN,SMAD6 |
| 5.646e-04 | -7.48 | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP | 156 | 29 | 17377 | 1707 |
EML5,PDK1,RNF144A,WLS,ST6GAL1,CYTH3,RAPGEF4,SLC25A27,PRRG1,SELL,TDRKH,PLEKHA1,TTC28,SESN1,ID3,TGFBR3,BACH2,IGF1R,RALGPS2,MYC,RGS10,ACVR2A,ADCY6,LRP6,ZBTB20,ST8SIA1,RNF122,DIRC2,AMPD1 |
| 5.655e-04 | -7.48 | superpathway of cholesterol biosynthesis | BIOCYC pathways | META_PWY66-5 | 23 | 9 | 902 | 105 |
CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,SQLE,DHCR7,HMGCR |
| 5.686e-04 | -7.47 | GO_CELL_CELL_ADHESION | MSigDB lists | GO_CELL_CELL_ADHESION | 584 | 82 | 17377 | 1707 |
CELSR3,IL15,GATA3,LILRB1,PKP2,CADM2,STAT5B,NRXN1,COL14A1,DOCK2,CBLN1,CTNNA2,PCDH7,EPCAM,EOMES,ITGB3,COL19A1,PERP,DOCK8,CYP1B1,FER,ITGB7,PTPRU,PTPN6,PREX1,NLGN4X,AMIGO1,TMEM47,BATF,DSP,JAM3,SMAD3,NCAM2,LAMB1,ATG5,TNFSF4,CTNND2,BCL11B,TYRO3,PCDH18,RUNX2,CELSR1,ROBO2,PTPRD,BVES,CD276,FZD8,CLSTN2,GAS6,SATB1,CD7,IL18R1,NEDD4,PCDHB14,CNTN4,SLC7A11,FLRT3,DSG2,LRP6,JAM2,STXBP1,ZFP36L2,SYK,CDH26,PCDH10,PODXL2,DCHS1,MAFB,SDK1,FNDC3A,LEPR,NEGR1,CEBPB,PTPRC,PCDHB7,FAT4,CLDN12,THBS4,FAT1,CDH17,CDH2,NPHP1 |
| 5.687e-04 | -7.47 | supramolecular fiber organization | biological process | GO:0097435 | 425 | 62 | 17256 | 1658 |
WASF3,SORBS1,INPPL1,FGF13,TMSB15A,RHOBTB1,RHOD,SLK,EPS8,MYO1B,COBLL1,PKP2,HDGFL3,ADD2,SORBS3,COL14A1,RAC3,PPP1R9A,FHOD3,SPIRE1,PLS3,SCIN,FSD1,RND2,FRY,POF1B,MARCKS,LOXL4,CTTN,SERPINH1,PACSIN1,FIGN,PDGFRB,CYP1B1,DBN1,MICAL2,EVL,MYLK3,RHOQ,DSTN,CAP2,PREX1,OBSCN,HIP1,PLS1,VIM,DSP,BAIAP2,MAP10,SNCA,GSN,RND3,ADAMTS3,FAT1,ALDOA,P4HA1,TMOD2,MYOM2,TPM1,COBL,B4GALT7,SHTN1 |
| 5.699e-04 | -7.47 | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | MSigDB lists | ZHANG_TARGETS_OF_EWSR1_FLI1_FUSION | 86 | 19 | 17377 | 1707 |
FADS1,MSX1,TRIM2,MYO10,ST6GAL1,CRIP2,AK4,SEL1L3,STEAP1,GABARAPL1,GLCE,CEBPB,NELL2,CHN2,PRKCB,MYC,VWA5A,NPTXR,IL1RAP |
| 5.702e-04 | -7.47 | mucinous_carcinoma | COSMIC cancer mutations | mucinous_carcinoma | 460 | 67 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PDGFRB,PRKACB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,EPHB1,PKN1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,MAPKAPK2,TRIB3,FGR,PKN3,MAP2K6,AKT3,NEK11 |
| 5.732e-04 | -7.46 | arm | COSMIC cancer mutations | arm | 1355 | 168 | 17385 | 1698 |
MYCBP2,PPP4R4,GRIK2,KIF5A,LDLR,PTPN21,LILRB1,PRKCA,NOVA1,RAC3,HMCN1,TRPS1,EPCAM,CPNE2,FBXO32,KCNAB1,GRHL1,DNAH6,SLC16A2,SERINC2,LIN7A,KIAA1614,SLC2A12,VWA5A,PTPRE,TLR4,SLIT2,ZNF391,ATL1,DCDC1,DCC,ANK2,DSTN,LRRK2,MSRB3,CR2,TNS1,EML1,TRIM9,TMEM132B,GPRC5B,MAP2,CCBE1,RASGRF2,TECPR2,ERCC5,ZBTB20,PPARGC1A,MAGI2,GPT2,SV2B,CELSR1,PTPRD,ATP6V1E2,GALNT13,FOXG1,SPINK5,CHD5,FHOD3,MECOM,SEMA4F,APLF,CACNB2,LRP6,SLC16A9,LOXL4,NIPAL2,FAM155A,ZNF518B,GLIS1,CHRM3,PARD3B,STAT4,RAPGEF4,KIAA1324L,PDE8A,PRDM1,SNAP25,KHDRBS2,GRIK4,XKR9,ADAMTS3,SH3BP4,INHBE,PTPRN2,OSBPL6,DMXL2,SORBS1,CFH,ST14,GALNT6,XYLT1,HECW2,KIF21B,TNKS1BP1,ZSCAN5A,COL22A1,NELL2,PPFIBP1,MAP7,MET,DNAH5,NTNG1,SCN3A,DOCK8,KCNB2,SEMA6C,GLI1,DPP10,FER,MYLK3,B3GALT1,FZD4,TDRD3,KCNH5,NLGN4X,TCEAL3,FGFR1,ENTPD1,IQCK,PTPRJ,IQCH,BACH2,GBP1,PTK7,LAMB1,CCNA1,PTPRS,TNFSF15,MID1,MAN2B2,WDR17,ENO2,PRSS16,CLGN,IPO5,COL4A5,SLC12A6,EPHB1,RGS7,COL27A1,NEDD4,RAB11FIP5,PRKCD,GAS2L3,EHD3,IQGAP3,ARAP2,PTPN13,PRICKLE1,SNTB1,RERE,PTPRC,DPY19L2,FGR,PCDHB7,FAT4,PLOD2,TERT,L3MBTL4,PRCP,ZNF214,PLXDC2,SLCO5A1,DLG2,TBC1D4,KIF1B,FILIP1 |
| 5.756e-04 | -7.46 | nicotinamide nucleotide biosynthetic process | biological process | GO:0019359 | 68 | 16 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,PFKFB2,OGDHL,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1,PARP9 |
| 5.756e-04 | -7.46 | pyridine nucleotide biosynthetic process | biological process | GO:0019363 | 68 | 16 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,PFKFB2,OGDHL,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1,PARP9 |
| 5.778e-04 | -7.46 | endoplasmic reticulum lumen | cellular component | GO:0005788 | 297 | 46 | 18223 | 1724 |
COL9A3,FN1,BACE1,C4A,DNAJC3,COL18A1,COL4A5,NOTUM,GAS6,CANX,COL14A1,COL27A1,TXNDC5,COL22A1,BCHE,COL25A1,STC2,CHRDL1,COL19A1,SERPINH1,ESD,FKBP14,COL9A2,CKAP4,CES3,IGFBP3,QSOX1,ENAM,COL6A2,EVA1A,COL4A3,SLC27A2,TMEM43,COL4A4,EDEM3,COLGALT2,FBN1,P4HA2,CSF1,WFS1,LAMB1,PTPRN2,P4HA1,RCN3,BMP4,CDH2 |
| 5.798e-04 | -7.45 | regulation of vesicle-mediated transport | biological process | GO:0060627 | 502 | 71 | 17256 | 1658 |
EPHA3,DOC2A,EXPH5,PRKN,SYT12,C4A,LDLR,VAMP8,LILRB1,SYT14,PCLO,TBC1D30,DOCK2,NCS1,ADPRHL1,UNC13B,RAB26,PACSIN1,RAB27B,GAB2,TBC1D8,FER,TNK2,DNAJC6,LRRK2,SYNJ2BP,TBC1D16,C4BPB,SNCA,TRIM9,INSIG1,NCKAP1L,APELA,ITGA2,INPP5F,ATG5,SEPT5,NRP1,MAGI2,TC2N,STON2,NECAB2,STXBP5L,LGALS3,BVES,TBC1D1,STXBP6,OPHN1,BTBD9,GAS6,PFN2,GAS1,GATA2,CADPS2,LMAN2,TBC1D9,STXBP1,SYK,FES,RIMS2,RAB3B,TBC1D8B,RAPGEF4,PACSIN3,HIP1,RACK1,TBC1D2,DKK1,FGR,SH3GL2,TBC1D4 |
| 5.807e-04 | -7.45 | ACVR1 (activin A receptor type 1) | protein interactions | 90 | 84 | 19 | 17029 | 1718 |
PAK1,RAB3B,ACVR1,BMPR2,SMAD9,LRRIQ1,RAB6B,RHOD,NUAK2,PLEKHB1,CHN1,INHBC,RAP2A,RASD2,TSC22D1,ACVR2A,BMPR1A,SMAD6,RRAS2 |
| 5.809e-04 | -7.45 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP | 171 | 31 | 17377 | 1707 |
ARHGAP26,VAV3,CD55,LANCL3,FGF13,RNF144A,ELOVL7,RAPGEF4,TNFAIP8L2,SLC25A27,SELL,RASA3,COBLL1,PRKCQ,GRK6,SFXN3,CD7,KBTBD11,DOCK2,ATP10D,SMPDL3B,QPRT,EOMES,FRY,BACH2,CDC14B,PRKCB,GPR155,HS3ST3B1,ATP2B1,B4GALT7 |
| 5.809e-04 | -7.45 | GSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | MSigDB lists | GSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | 171 | 31 | 17377 | 1707 |
LATS2,SESN2,EHHADH,SH2D2A,AKAP5,PSTPIP2,SLK,LILRB1,HIP1,MAFB,C20orf194,ATP1B1,FAM13A,SLCO3A1,IL18R1,C1orf174,BATF3,RANBP2,TLR3,TGFBR3,C1orf21,SLC2A6,EIF1,RAP2A,PGM2L1,MORN2,KIF21A,VGLL4,ATP2B4,ATP2B1,CYP1B1 |
| 5.829e-04 | -7.45 | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_UP | 149 | 28 | 17377 | 1707 |
ANO10,CARD6,KLF8,EBPL,KLHL3,TES,GPR65,ELOVL7,RAPGEF4,UBAC2,TMTC4,SELL,CALCRL,VIM,ISYNA1,NPC2,SESN1,IKZF2,HERPUD1,HMGCS1,GPRC5B,MPP7,ALDOA,ITGB3,RUNDC3B,INPP5F,RRAS2,SLFN5 |
| 5.839e-04 | -7.45 | intercalated disc | cellular component | GO:0014704 | 50 | 13 | 18223 | 1724 |
PAK1,SCN5A,FGF13,SCN1B,TMEM65,ANK2,DSG2,PKP2,ATP1B1,SCN2A,DSP,CDH2,GJC1 |
| 5.845e-04 | -7.44 | V$AP3_Q6 | MSigDB lists | V$AP3_Q6 | 224 | 38 | 17377 | 1707 |
CGN,CACNG3,FN1,FGF13,PLAG1,MSR1,ATP6V1E2,NTRK3,RBM11,RADIL,SEMA6A,NEO1,TRPS1,FOXP2,BAG3,PPM1E,LRRN1,LHX6,GAN,GFI1,ETV1,VNN2,UNC5C,MEIS2,COL4A3,COL4A4,RAPGEF4,FGF17,NPC2,ZFPM2,SAV1,NSD1,ARHGAP21,ERN1,SPRY4,SEPT5,NRP1,TMEFF2 |
| 5.853e-04 | -7.44 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_DN | 186 | 33 | 17377 | 1707 |
MXI1,RHOQ,SKAP2,TMEM43,RAPGEF2,MCTP2,PRDM1,ARRDC4,FNDC3A,DENND3,DSP,ATP10D,SLC19A2,DACH2,SMAD3,EBF1,PTPRJ,SEMA4F,SLC30A4,ZFYVE28,SH3RF1,MAP2K6,ERN1,ITGA2,CDH17,ATRNL1,DLG2,BEND4,LMAN2,GEM,ETV1,RAPGEF5,ZFP36L2 |
| 5.853e-04 | -7.44 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP | 186 | 33 | 17377 | 1707 |
ACSL1,IL15,ST6GAL1,CYP4V2,CTBP2,GDPD5,SLCO3A1,IL18R1,FHOD3,CA2,BCL6,TSC22D1,ACVR2A,PTPRE,FES,B4GALT6,VAV3,ANTXR2,GCNT2,RHOQ,SHISA2,MFSD6,BCL11A,DOCK7,GPRC5B,MYADM,CDH17,RAB31,ZBTB20,LRRK1,GEM,CTNND2,MEF2C |
| 5.868e-04 | -7.44 | Rap1 signaling pathway | KEGG pathways | ko04015 | 210 | 37 | 7161 | 730 |
LPAR2,ID1,FGF13,P2RY1,LCP2,PRKCA,PFN2,RAC3,SIPA1L2,IGF1R,ITGB3,ADCY6,MET,TLN2,RAPGEF5,PDGFRB,VEGFC,FGFR4,RAPGEF2,RAPGEF4,ADCY1,EFNA3,FGF12,FGF17,SKAP1,PLCB1,MAGI3,FGFR1,GNAI1,PRKCB,MAP2K6,AKT3,GNAO1,CSF1,MAPK13,HGF,MAGI2 |
| 5.868e-04 | -7.44 | Rap1 signaling pathway | KEGG pathways | hsa04015 | 210 | 37 | 7161 | 730 |
LPAR2,ID1,FGF13,P2RY1,LCP2,PRKCA,PFN2,RAC3,SIPA1L2,IGF1R,ITGB3,ADCY6,MET,TLN2,RAPGEF5,PDGFRB,VEGFC,FGFR4,RAPGEF2,RAPGEF4,ADCY1,EFNA3,FGF12,FGF17,SKAP1,PLCB1,MAGI3,FGFR1,GNAI1,PRKCB,MAP2K6,AKT3,GNAO1,CSF1,MAPK13,HGF,MAGI2 |
| 5.874e-04 | -7.44 | GO_CATION_TRANSPORT | MSigDB lists | GO_CATION_TRANSPORT | 740 | 100 | 17377 | 1707 |
CACNG3,ATP8A1,MCOLN3,SLC2A13,SLC7A2,ITPR2,CACNB4,NCS1,SLC9A7,KCNAB1,KCNN2,CHRNA5,SLC22A18,SLC10A7,KCNS3,SERINC2,TRPC1,CNNM2,STEAP3,SLC2A12,TMEM37,SCN2A,ATP6AP1L,KCNB2,SCN3A,GPM6A,KCNIP3,SLC3A2,CSN2,KLHL3,SLC39A8,ANK2,KCNH5,JPH1,ATOX1,CHRNA6,ATP1B1,KCND3,ASPH,ATP10D,SNCA,SFXN1,SLC7A1,SLC39A14,KCNMB4,PRKCB,ATP7B,KCNG1,BBC3,SLC9B1,DENND5B,KCNV1,PRKAA2,ANO10,TMEM63C,SCN5A,SERINC5,SLC6A9,SCN8A,SLC25A27,ATP6V1E2,SLC36A4,GAS6,SLC12A6,NDFIP2,KCNC4,MCU,MCOLN2,KCNJ4,SLC30A4,SCN1B,CACNB2,BHLHA15,KCNMB3,SGK1,SLC6A15,NIPAL2,SYK,ATP2B1,TRPM4,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RASA3,CALCRL,RYR2,STEAP1,PTPRC,TMCO3,CACHD1,KCNK15,SLC2A6,SLC1A5,TRPC3,DDIT3,ATP2B4,CACNA2D1,ATP1A3,TPT1 |
| 5.917e-04 | -7.43 | MODULE_255 | MSigDB lists | MODULE_255 | 400 | 60 | 17377 | 1707 |
SV2B,MOCOS,ACVR1,ACSL1,FN1,AASS,SLC25A27,BEGAIN,HBE1,SCD,MAPK4,PRDM8,ISYNA1,CBLN1,IL18R1,BAG3,EPHB6,IPCEF1,PDE4D,FAR2,TBC1D9,LRP3,SP140L,MED12L,KDM5B,TBC1D8B,KLHL4,HOMER2,WDR25,OBSCN,SDC3,AGAP2,PRDM1,TMEM47,AMIGO1,SAV1,FGFR1,RERE,DEXI,SMAD3,SPNS1,CXCL10,GSN,ADAMTS3,MAP2K6,CCBE1,CSF1,ABI3,WDR19,ALDOA,NCOA7,DYNC2LI1,PLEKHG1,NXPH4,GEM,TNFSF4,LARP1,PKIA,SLC43A1,RRAGD |
| 5.920e-04 | -7.43 | positive regulation of protein phosphorylation | biological process | GO:0001934 | 991 | 126 | 17256 | 1658 |
EPHA3,NEK10,ACSL1,AVPI1,ACVR1,FGF13,IL15,NTRK3,LCP2,PRKCA,SNX9,PIBF1,DDR1,TNKS1BP1,PPP1R9A,STK24,GSDME,TLR3,RAP2A,ITGB3,ACVR2A,DAB2IP,EPHB6,MET,TLR4,HSPA2,PRKACB,RASGRP1,PDGFRB,FZD1,IGFBP3,TNK2,GCNT2,FZD4,TGFA,LRRK2,ADCY1,PRKAR2B,WNT11,ACVR2B,ROR1,RARRES2,CD40,FGFR1,SNCA,INHBC,NRG3,GPRC5B,NCKAP1L,APELA,ERN1,MAP3K21,TNFRSF1A,DUSP19,TNFSF15,HGF,DIRAS1,BMPR1A,NRP1,MAPK10,MID1,CACUL1,CNTN1,TENM1,TYRO3,TNIK,NECAB2,BMPR2,EDA2R,PAK5,SLK,FZD8,LRP4,SORBS3,GAS6,P2RY1,TNFRSF10C,PKN1,EPHB1,TPD52L1,PFN2,TNFRSF19,BMP6,IGF1R,PRKCD,GHR,ADCY6,INAVA,AFAP1L2,IQGAP3,TNFRSF11A,SYK,SPRY2,PARP9,HMGCR,PAK1,FGFR4,VEGFC,MSTN,RAPGEF2,VLDLR,DUSP9,WWC1,STRADB,PDE8A,GAREM1,RACK1,PLCB1,TLR6,DKK1,MAPKAPK2,GPR37,PTPRC,DOCK7,PELI2,THBS4,MAP2K6,CSF1,INHBE,BMP4,LRRK1,CDH2,SEMA3A,SMYD3,MAP3K20,ATP2B4 |
| 5.931e-04 | -7.43 | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | 819 | 109 | 17377 | 1707 |
CREB3L2,DMXL2,MYCBP2,ACVR1,TRIM2,ID1,SCAMP1,DOCK1,RBFOX2,MYO1B,LDLR,RGS20,CTBP2,PRKCA,PIBF1,STK24,ZFYVE9,F3,MOK,TGFBR3,RPS6KA2,KAZN,FAM168A,TRPC1,SLIT2,IL1RAP,PRKACB,MEIS2,SKAP2,TDRD3,CAP2,YAP1,SATB2,ROR1,TTC28,CRYBG3,GNAI1,SMAD3,SLC7A1,RANBP2,KPNA3,WWTR1,SEMA3C,ZBTB20,INPP5F,BMPR1A,MBOAT2,MID1,UST,WASF3,ZHX3,SEC24D,ITGA6,SLK,EPS8,KIF5C,PSD3,CREB5,CHSY1,RGS7,DOK5,PPP2R3A,NEDD4,MECOM,GALNT1,IGF1R,MYC,GTF2F2,LIMCH1,RRAS2,SMAD6,FAM155A,ZFP36L2,ATP2B1,DUSP1,MN1,VEGFC,MICAL2,BDNF,RIN2,ARAP2,KDM5B,CRIM1,MYO10,PTPN13,FOXN3,RAPGEF2,VLDLR,ARID5B,FERMT2,WWC1,PDE8A,CDC42BPA,FNDC3A,MAP1B,CTIF,DKK1,HEG1,ID3,KIAA0355,PLOD2,FAT1,RAB31,SFMBT1,FNBP1L,CDH2,ATP2B4,BTRC,DOCK9 |
| 5.949e-04 | -7.43 | middle_lobe | COSMIC cancer mutations | middle_lobe | 1402 | 173 | 17385 | 1698 |
DOC2A,FAM171B,CGN,PAGE1,ACSL1,TCP11L2,LANCL3,GRIK2,HEBP1,ALG1L,ITPR2,ABAT,HMCN1,SLCO3A1,EYA4,SLC9A7,RTN1,DLX6,PPFIA2,ANKFN1,ATRNL1,OR2W3,THSD1,CPE,SLIT2,GLDC,MARK1,DCDC1,ACVR1C,ANK2,KLHL4,DEPTOR,ENPP1,ATP7B,PIK3C2B,ERCC5,DLX2,UNC5B,MAGI2,NEUROG2,MLLT3,SCN5A,INPPL1,STXBP5L,ITPRIP,PTPRD,STXBP6,UBASH3B,SETBP1,LAMC3,FHOD3,DDIT4,FRY,IGF1R,BCHE,FRAS1,PDE10A,ZIC5,SRGAP1,SNX7,BOD1,PAK1,PCDH10,SLITRK2,COL4A4,PARD3B,ZNF605,TMTC4,PACSIN3,RYR2,PEX5L,ZBBX,SDK1,AMDHD1,CACHD1,GSTO2,ADAMTS3,PELI2,FAT1,PTPRN2,HOXD13,DISP2,FNBP1L,CDH2,SEMA3A,SIX2,AMPD1,DOCK9,CREB3L2,ZNF516,XYLT1,LRRCC1,PKP2,COL18A1,NTRK3,KIF21B,DOCK2,TIAM2,ZFYVE9,CCDC120,COL22A1,ASNS,SETDB2,KMO,ALDH1L1,ZNF521,MET,DNAH5,KCNB2,SCN3A,IGFBP3,INTU,COL6A2,TDRD3,THSD4,PANK1,CHRNA6,VIM,WNT11,DSP,PAGE5,MAGI3,FGFR1,SNCA,POPDC3,GBP1,LAMB1,RGS10,RCN3,KLF5,STON2,CTNND2,THOC3,PCDH18,PLSCR4,GCAT,ARHGEF11,GRB14,MCTP2,COL4A5,EPHB1,INPP1,BMP6,ARHGAP44,KCNJ4,LRRC55,TECPR1,GAS2L3,TSC22D1,SH3PXD2B,IQGAP3,SPRY2,MED12L,FES,TRPM4,MICAL2,LCA5,CRIM1,CACNA1E,RASA3,ATP11A,ZFPM2,ZIC1,DPY19L2,PTPRC,PCDHB7,FAT4,SLCO5A1,ZNF808,KIF21A,HK1,CACNA2D1,CRISPLD1 |
| 5.985e-04 | -7.42 | Integration of energy metabolism | REACTOME pathways | R-HSA-163685 | 111 | 22 | 10287 | 971 |
PRKAA2,GNG12,AKAP5,CACNA1E,RAPGEF4,ADCY1,FASN,ARL2,PRKAR2B,ITPR2,SNAP25,PRKCA,PLCB1,GNAI1,CACNB2,GNB4,KCNS3,ADCY6,MARCKS,STXBP1,CHRM3,PRKACB |
| 5.993e-04 | -7.42 | TGTATGA,MIR-485-3P | MSigDB lists | TGTATGA,MIR-485-3P | 142 | 27 | 17377 | 1707 |
GPM6A,MEIS2,PPP4R4,RUNX2,RNF145,MYO1B,GRID1,MAFB,ZIC2,ATP1B1,C3orf70,KIAA1217,NRXN1,RNF44,GNAI1,MKX,DAGLA,MAPKAPK2,ADAMTS3,SEMA3C,PIK3C2B,KIF21A,PDE4D,PPARGC1A,MAGI2,PURG,SNPH |
| 5.993e-04 | -7.42 | V$MYB_Q6 | MSigDB lists | V$MYB_Q6 | 232 | 39 | 17377 | 1707 |
LRFN5,PCSK1N,PPP4R4,DOCK1,GCAT,OTX1,PFN2,FSTL5,SLC9A7,CHN1,ZNF362,NOVA2,DACT1,CACNB2,FRAS1,STC2,CHRDL1,TRPC1,BEND4,FBXL2,DLGAP1,BDNF,MICAL2,GCNT2,NR6A1,ESRRG,ANK2,FGF12,PRICKLE1,ID3,ADAMTS3,WFS1,ALDOA,B3GALT2,KLF5,NKX2-8,NR3C2,CRISPLD1,PHC1 |
| 5.993e-04 | -7.42 | V$FREAC3_01 | MSigDB lists | V$FREAC3_01 | 232 | 39 | 17377 | 1707 |
BCL11B,TCP11L2,ZIC2,NTRK3,LCP2,NOVA1,SEL1L3,TNFRSF19,HMCN1,NEDD4,TBC1D19,EFEMP1,CHN1,FOXP2,ATXN7L1,ZNF362,ZIC5,ZNF521,SGK3,PRICKLE2,PPP2R2B,ETV1,GFRA1,LRP3,POU3F3,PAK1,MEIS2,WISP3,ESRRG,AGPAT4,PRDM1,TCERG1L,MBNL2,LRAT,HERPUD1,BCL11A,PELI2,GNAO1,ZBTB20 |
| 5.998e-04 | -7.42 | inner ear development | biological process | GO:0048839 | 175 | 31 | 17256 | 1658 |
CELSR1,GABRB2,DCHS1,MCOLN3,OTX1,SLC25A27,GATA3,MAFB,CEBPA,NTRK3,ROR1,ATOH1,FOXG1,HOXA1,FGFR1,ZIC1,GSDME,MAPKAPK2,FAT4,INSIG1,PDZD7,GATA2,DLX6,PTK7,MYO3B,TFAP2A,LIN7A,BMP4,ATG5,SPRY2,PDGFRB |
| 6.004e-04 | -7.42 | dendrite development | biological process | GO:0016358 | 95 | 20 | 17256 | 1658 |
FARP1,RBFOX2,LRP4,SHANK2,VLDLR,SLITRK5,EPHB1,BAIAP2,CTNNA2,MAP1B,RERE,MAP1A,MAP2,MATN2,PRKG1,GRIP1,NRP1,SEMA3A,ZNF365,CTNND2 |
| 6.053e-04 | -7.41 | GSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP | MSigDB lists | GSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP | 164 | 30 | 17377 | 1707 |
ARAP2,CRIM1,PTPN13,MCTP2,TNFSF13B,PREX1,ZDHHC15,ACO1,HIP1,ADAMTS6,DOCK5,GDPD5,RAC3,SMAD3,ENTPD1,IKZF3,ZBTB38,HPSE,SOAT2,PIK3AP1,PLXDC2,GPR155,CSF1,ERN1,DAB2IP,TMEM37,LRRK1,PTPRE,MED12L,HACE1 |
| 6.096e-04 | -7.40 | VARELA_ZMPSTE24_TARGETS_UP | MSigDB lists | VARELA_ZMPSTE24_TARGETS_UP | 37 | 11 | 17377 | 1707 |
MAPKAPK2,RGS16,ATF4,MYC,ATF3,SESN1,ZFP36L2,LEPR,BAIAP2,CYP26A1,DDIT4 |
| 6.098e-04 | -7.40 | regulation of platelet aggregation | biological process | GO:0090330 | 17 | 7 | 17256 | 1658 |
PRKCQ,ABAT,PRKCA,SYK,UBASH3B,PRKCD,PRKG1 |
| 6.122e-04 | -7.40 | V$AREB6_03 | MSigDB lists | V$AREB6_03 | 240 | 40 | 17377 | 1707 |
DOC2A,ARHGAP26,PHACTR3,ANKRD13B,ITGA6,RIMKLA,FAM117B,NTRK3,CHAC1,IKZF2,HMCN1,SLC9A7,MTUS1,EPCAM,SPEG,NUMBL,SLC7A11,LRRN1,TACC2,DSG2,SMTN,NBEA,VGLL4,GLI1,SSH3,BCL7A,MEIS2,DSTN,STRADB,SNAP25,SKAP1,KHDRBS2,EBF1,DDAH1,FGR,DLG2,MLLT3,MMP16,FOXA1,FRMD5 |
| 6.124e-04 | -7.40 | GSE7460_TCONV_VS_TREG_LN_DN | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_DN | 194 | 34 | 17377 | 1707 |
ATP9A,UBASH3B,CYP4V2,ADAMTS6,HOPX,GPR15,FBXO32,ASNS,IGF1R,ABCA5,CNKSR3,ZDHHC23,PROS1,ERGIC1,SH3BP2,TMEM65,WLS,PRICKLE1,C3orf70,PEAK1,SESN1,GABARAPL1,ENTPD1,ARHGAP21,LMLN,MATN2,HK2,INPP5F,SH3BGRL2,GEM,TANC2,NRP1,TBC1D4,RRAGD |
| 6.130e-04 | -7.40 | WILCOX_RESPONSE_TO_PROGESTERONE_UP | MSigDB lists | WILCOX_RESPONSE_TO_PROGESTERONE_UP | 135 | 26 | 17377 | 1707 |
PLA2G4A,FADS1,MVK,LDLR,TTC30A,SCD,SMPDL3B,CYP51A1,HMGCS1,IDI1,KIAA0895,INSIG1,ITGBL1,MSMO1,TDO2,EIF1,MAP7,SGK1,KLF5,DHCR7,ETV1,SMPDL3A,PCSK6,TLL2,ABCG1,HMGCR |
| 6.131e-04 | -7.40 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | 509 | 73 | 17377 | 1707 |
EPHA3,PHACTR3,PLBD2,AMOTL1,AVPI1,SORBS1,TRIM16,CELSR3,FAM198B,NRXN1,ABHD4,EYA4,NOS1AP,F3,TMEM53,BAG3,HPS1,PMAIP1,MARVELD2,CNNM2,PACSIN1,NEB,NR6A1,TES,PTK7,WFS1,CCNA1,BDH2,BMP1,ERCC5,LRRC27,RGS16,TMEM132C,GRB14,FBXO4,GABRB2,CBS,GTF2IRD1,COL4A5,INPP1,TSPAN17,RALGPS2,IGF1R,SCN1B,EIF1,PRKCD,GAS2L3,RASD2,TRIM3,TSPAN13,MYO6,RRAS2,DUSP1,UNC5C,QSOX1,NR4A1,CRIP2,NUAK2,GALNT14,NPDC1,GPR19,CPEB1,MYADM,PMEPA1,OSBPL5,RAI14,LAPTM4B,SFMBT1,HOXD13,RPS12,NKX2-8,FOXA1,ZNF235 |
| 6.144e-04 | -7.39 | GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_UP | 179 | 32 | 17377 | 1707 |
ACSL1,TUBA1A,FLVCR2,STXBP6,IPO5,ARID5B,MRPL22,HIP1,ENAH,RNF24,ZBBX,TTLL7,PFN2,AARS,EML1,TRIB3,KCNK15,ICA1,CHRNA5,SLC7A11,NACC2,INHBE,TFAP2A,TUFT1,COL19A1,TPM1,NEUROG2,NR3C2,PERP,ATP2B4,RRAGD,DUSP1 |
| 6.144e-04 | -7.39 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_DN | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_DN | 179 | 32 | 17377 | 1707 |
MN1,PDLIM7,ACSL1,ALOX5AP,SLC39A8,TGFA,CYB5R2,ELOVL7,LILRB1,FERMT2,AK4,PSD3,HECW2,BATF,DNER,DENND3,TBC1D16,TBC1D30,DDIT4,MCOLN2,SLC7A11,PIK3AP1,ZNF697,MFSD2A,TECPR2,BCL6,HS3ST3B1,SH3PXD2B,MET,PTGES,CKAP4,SMPDL3A |
| 6.144e-04 | -7.39 | GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_DN | 179 | 32 | 17377 | 1707 |
ACSL1,DYRK3,ZCCHC24,NRN1,TNFRSF10C,EPHB1,APBA1,LGI2,KCTD15,UNC13B,SLC7A11,FUT9,FRAS1,LHX6,CHRDL1,ZNF460,CEBPD,VNN2,GCA,SKAP2,SMAD9,TUBA1A,TGFA,LITAF,GALNT14,TLR6,CEBPB,MAP2,ITGA2,TUFT1,RNF130,TTC39A |
| 6.147e-04 | -7.39 | MODULE_136 | MSigDB lists | MODULE_136 | 442 | 65 | 17377 | 1707 |
ACVR1,AASS,BEGAIN,GATA3,MAPK4,F3,BAG3,TYMP,PDE4D,SP140L,KLHL4,SOX21,AMIGO1,SAV1,SMAD3,SPNS1,ENPP1,CCBE1,ALDOA,ABI3,NCOA7,PLEKHG1,TNFSF4,RRAGD,PCSK5,SV2B,MOCOS,SLC25A27,SCD,HBE1,PRDM8,ISYNA1,USP30,IL18R1,SYCP2,RALGPS2,DHRS12,IPCEF1,FAR2,TBC1D9,LRP3,MED12L,MSX1,SH3BP2,KDM5B,TBC1D8B,GSTM4,OBSCN,SDC3,WDR25,AGAP2,CCNG1,PRDM1,LHPP,RERE,DEXI,GALNT3,CSF1,WDR19,DYNC2LI1,NXPH4,TNFRSF17,PKIA,LARP1,SLC43A1 |
| 6.162e-04 | -7.39 | skin-acral-malignant_melanoma | COSMIC cancer mutations | skin-acral-malignant_melanoma | 265 | 43 | 17385 | 1698 |
DOC2A,PCDH18,CACNG3,ARHGEF11,LRP4,ARHGAP22,SETBP1,HBE1,COL4A5,SLC12A6,COL14A1,BBS9,BMP6,FOXP2,SLC30A4,EHD3,COL19A1,SLC16A9,LIMCH1,TLN2,TLR4,KCNB2,SCN3A,GDAP1,ABCC4,DCC,SPOCD1,CRIM1,OGDHL,ACO1,YAP1,KCND3,CD40,PTPRC,ZNF711,TCF7L1,FAT4,TERT,ITGBL1,CDH17,UNC5B,NPHP1,MAST1 |
| 6.163e-04 | -7.39 | PEDRIOLI_MIR31_TARGETS_DN | MSigDB lists | PEDRIOLI_MIR31_TARGETS_DN | 376 | 57 | 17377 | 1707 |
PLA2G4A,PRKAA2,LATS2,MYO1D,MYCBP2,SV2B,IL32,DOCK1,CLGN,BVES,CD276,BACE1,RGS20,SETBP1,RASD1,PCLO,PPP1R9A,NOS1AP,HSPA12B,NEO1,PCDHB14,SLC22A17,SLC7A11,PDZD7,CACNB2,DSG2,SCARF2,OPN3,EPHB6,CAND2,DISC1,ITGB7,CD55,FGF12,LITAF,RAB38,SLC46A3,PLCB1,PLEKHB1,SMPDL3B,ARMC4,EBF1,CAMK2N1,ZNF396,INHBC,KCNMB4,PRCP,RASGRF2,EMILIN2,SVIL,KLF5,KIF21A,SPRY4,NRP1,OSBPL6,MMP16,HEY1 |
| 6.251e-04 | -7.38 | ACTG1 (actin gamma 1) | protein interactions | 71 | 153 | 29 | 17029 | 1718 |
DBN1,PDLIM7,TNIK,DISC1,FN1,EHHADH,LGR4,UBASH3B,CAP2,DSTN,LRRK2,FEZ1,CTBP2,COTL1,PFN2,PPP1R9A,SCIN,GSN,ABLIM1,MAP1A,SH3GL2,MYC,DUSP19,GAN,PLD1,CTTN,ERRFI1,NR3C2,SFN |
| 6.279e-04 | -7.37 | small molecule binding | molecular function | GO:0036094 | 2448 | 284 | 17224 | 1680 |
ACVR1,ATP8A1,TUBE1,CTBP2,BCAN,PRKCA,RAC3,AARS,STK24,MOK,BAG3,DNAH6,RAP2A,RAB26,GLDC,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,GNAI1,ENPP1,PLK2,ATP7B,ALDOA,BDH2,MAPK13,DIRAS1,DNHD1,CRYL1,CARS,LATS2,ALOX5AP,SCN8A,SLK,DHCR24,GPSM2,SLC1A3,ADSSL1,CHD5,GRPEL2,ADCK1,APLF,PRKG1,LMAN2,ALPK1,FIGN,MAST4,HMGCR,PNP,MYO10,RAPGEF4,FASN,RYR2,NPC2,CDC42BPA,CLN5,DHX32,RIMKLB,PKN3,SQLE,DHCR7,SLFN5,TRPC3,GVINP1,ACSM3,EPHA3,MTG1,DNM3,RHOD,MYO1B,CHUK,MAPK4,GRK6,COLEC10,DDR1,TXNRD3,SPEG,ASNS,KMO,STARD4,PDE4D,RAB27B,ARL4D,DNAH5,MYLK3,GAPDH,GARS,PDK1,PFKFB2,CYB5R2,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,ATP10D,MAGI3,FGFR1,SNCA,ENTPD1,POPDC3,PRKCB,TDO2,MAP3K21,PAM,HPGD,P4HA1,BMPR1A,MAPK10,RAB30,MYO1D,GCAT,ATP9A,ARL2,CBS,KIF5C,P2RY1,PKN1,EPHB1,FTCDNL1,IRX5,HMGCS1,SOAT2,SGK3,PRKG2,PHYKPL,DYNC2H1,MYO6,SEPT3,FES,PARP9,PFKFB4,TRPM4,OPLAH,ALDH2,RAB6B,RAPGEF2,AK4,ATP11A,GUCY1A2,TRIB3,ID3,FGR,PLOD2,GNAO1,AKT3,OSBPL5,NEK11,PIP5KL1,HK1,LRRK1,CMPK2,ATP2B4,ATP1A3,NMNAT3,ACSL1,MVK,KIF5A,UGDH,ASS1,ABAT,ITPR2,RND2,TUBB4A,RPS6KA2,AADAT,KCNAB1,AKAP7,CNNM2,TRPC1,EPHB6,PDGFRB,PRKACB,ATL1,TNK2,MARK1,SESN2,ABCC4,CEMIP2,ROR1,SGK2,SESN1,GRK3,DYRK1B,AK1,FAM114A2,P4HA2,ERN1,PIK3C2B,RRAGD,GPT2,TYRO3,PRKAA2,MOCOS,RUNX2,BVES,RHOBTB1,RIMKLA,RASL11B,PHGDH,HSPA12B,PRTFDC1,ZBTB38,EEF2,IGF1R,ABCA5,PDE10A,HS3ST5,ADCY6,NOS3,FGFR4,PAK1,RHOQ,SLC27A2,OBSCN,STRADB,LDHD,MAPKAPK2,HK2,RAB31,PANK3,NEK10,NTRK3,KIF21B,DDX60L,CYP26A1,RIDA,RPS6KL1,FABP6,MYO3B,ACVR2A,MYH15,FHIT,MET,HSPA2,CTH,FER,TUBA1A,MVD,FRK,TTLL7,ETNPPL,WARS,TPK1,PTK7,GBP1,SEPT5,MAST1,TNIK,DYRK3,BMPR2,PAK5,ARL15,NLRP14,RASD1,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,PCK2,RRAS2,SYK,ATP2B1,MICAL2,RAB3B,NUGGC,OGDHL,NUAK2,AGAP2,MARS,PEAK1,LRAT,DDAH1,RND3,MAP2K6,FMO4,KIF21A,GEM,MAP3K20,KIF1B,ABCG1 |
| 6.289e-04 | -7.37 | GSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_UP | MSigDB lists | GSE21927_BALBC_VS_C57BL6_MONOCYTE_SPLEEN_UP | 157 | 29 | 17377 | 1707 |
GCA,VNN2,SLC40A1,MXI1,TSPAN15,AGPAT4,HIP1,CHUK,ZBBX,ARRDC4,ZNF618,GPR19,TRPS1,GALNT3,IRS2,BEX4,HLF,BACH2,SETDB2,ZNF438,FUT9,CLDN12,PELI2,DACT1,BDH2,DBP,FNBP1L,ZNF629,ALG10B |
| 6.289e-04 | -7.37 | GO_ACTIN_FILAMENT_ORGANIZATION | MSigDB lists | GO_ACTIN_FILAMENT_ORGANIZATION | 157 | 29 | 17377 | 1707 |
DBN1,WASF3,MICAL2,INPPL1,EVL,SORBS1,RHOD,DSTN,MYO1B,EPS8,PREX1,ADD2,COBLL1,SORBS3,PPP1R9A,SPIRE1,FHOD3,BAIAP2,SCIN,GSN,FRY,PDLIM3,FAT1,ALDOA,TMOD2,MARCKS,CTTN,PACSIN1,COBL |
| 6.334e-04 | -7.36 | angiogenesis | biological process | GO:0001525 | 302 | 47 | 17256 | 1658 |
EFNB2,AMOTL1,ACVR1,ID1,FN1,FZD8,ARHGAP22,COL18A1,OVOL2,SLC12A6,EPHB1,PRKCA,TYMP,ITGB3,TSPAN12,DAB2IP,LOXL4,SYK,SLIT2,PDGFRB,NOS3,CYP1B1,FGFR4,VEGFC,ATP5IF1,VAV3,ADM2,SH2D2A,CEMIP2,NR4A1,CALCRL,LEPR,JAM3,FGFR1,GPLD1,WARS,HPSE,PRCP,CCBE1,APELA,XBP1,EGFL7,KLF5,BMP4,UNC5B,NRP1,HEY1 |
| 6.359e-04 | -7.36 | cell junction assembly | biological process | GO:0034329 | 153 | 28 | 17256 | 1658 |
CDH26,SORBS1,UGT8,FN1,RHOD,ITGA6,ANK2,GJB2,OPHN1,FERMT2,ARL2,PKP2,TJP1,TNS1,WNT11,PRKCA,HEG1,PATJ,GJC1,EPB41L3,MPP7,MARVELD2,ITGA2,POF1B,CTTN,TLN2,CDH2,OCLN |
| 6.381e-04 | -7.36 | V$HFH1_01 | MSigDB lists | V$HFH1_01 | 225 | 38 | 17377 | 1707 |
BCL11B,C1QTNF3,DOCK1,GRIK2,OTX1,KCTD12,CREB5,LCP2,DOCK3,HMCN1,NEDD4,PPP2R3A,NEO1,PCDH7,EFEMP1,FOXP2,SLC10A7,PPP2R2B,NCAM1,ERRFI1,DUSP1,NR4A1,SLC39A8,NPM3,SHANK2,SATB2,PRDM1,ATOH1,TMEM47,CLN5,ISG20,BCL11A,KLF12,MCC,DLG2,NRP1,MBOAT2,MAPK10 |
| 6.394e-04 | -7.35 | NS-malignant_melanoma | COSMIC cancer mutations | NS-malignant_melanoma | 3494 | 393 | 17385 | 1698 |
FAM171B,GXYLT2,PPP4R4,TCP11L2,GRIK2,AASS,MCOLN3,ALG1L,NPM1,CTBP2,CEBPA,CADM2,PRKCA,DOCK3,KIAA1217,CA8,ABHD6,RAC3,NOS1AP,PCDH7,ZFYVE28,DNAH6,SLC16A2,PPFIA2,ATRNL1,BEND4,SP140,TMEM37,MAGEA6,VWA5A,TSHR,MEIS2,SMAD9,DCC,NR6A1,LRRK2,DNAJC6,ELMOD1,DEPTOR,TNS1,AHRR,ENPP1,SH3RF1,NCKAP1L,PLK2,CCBE1,SEMA3C,DSEL,UNC5B,DNHD1,SPOCK3,LRFN5,SCN5A,MRC2,CELSR1,OPHN1,TJP1,LRRC49,WDFY4,MECOM,MTUS1,NAV1,FRY,CNTN4,PIK3AP1,ZIC5,RUNDC3B,GRIP1,CPXM2,TOX,ALPK1,ST8SIA1,AGL,RIMS2,CHRM3,IGSF3,PTCH2,KCNQ3,TBC1D8B,COL4A4,ARID5B,DCHS1,EFHC2,FASN,KIAA1324L,RYR2,AIG1,ZBBX,PLCB1,MBNL2,ZNF558,SPATA7,DAGLA,TEX15,PLEKHH2,SH3GL2,ISM1,MATN2,LAPTM4B,ACSM3,EPHA3,ZNF516,FAM131C,CCDC110,GALNT6,GPR65,RGS20,COLEC10,NRXN1,COL14A1,SLC19A2,TIAM2,GPR15,ZNF827,ASNS,GPRIN1,COL25A1,ALDH1L1,NBEA,DNAH5,KCNB2,SCN3A,GAB2,DZANK1,VNN2,SSH3,COL6A2,PFKFB2,KCNH5,SHANK2,ADCY1,NLGN4X,SATB2,PRKCQ,DSP,TBC1D16,ATP10D,METAP1D,FGFR1,GJC1,SLC39A14,HTR7,ZNF711,IQCK,ARHGAP21,IQCH,WFS1,LAMB1,GRB10,MID1,PURG,STON2,HACE1,ANO10,CD276,BACE1,EPS8,HERC5,GABRR2,RGS7,NDFIP2,COL27A1,AFF2,GHR,DYNC2H1,NPTXR,TMC7,MN1,VAV3,ALDH2,SYNPO2,LCA5,RAB6B,CACNA1E,ZDHHC15,ATP11A,GUCY1A2,SNTB1,SKAP1,GPLD1,HEG1,CEBPB,GALNT3,PTPRC,NSD1,FGR,OR2T33,PCDHB7,TERT,OSBPL5,SLCO5A1,NEK11,GRIN2D,SHOX2,DCBLD1,LARP1,TLL2,EXPH5,NBPF4,ACSL1,CACNG3,UGT8,SYT12,PTPN21,ACTL8,FHDC1,C20orf194,LILRB1,ITPR2,FAM13A,DNER,CACNB4,IKZF2,HMCN1,FSTL5,FKBP11,ANKRD42,RTN1,LGI2,RPS6KA2,CPVL,ABI3BP,DLX6,ITGB3,ANKFN1,JAKMIP2,KIAA1614,PCOLCE2,PTPRE,OR2W3,NEB,SESN2,KCNIP3,SKAP2,COL4A3,ABCC4,ANK2,CR2,TMEM132B,TRIM9,GSN,HPSE,NCAM2,OXTR,TNFSF4,MAGI2,MLLT3,FRMD5,HS6ST3,CHMP4C,KCNV1,BCL11B,GPR63,SV2B,RGS16,ZNF395,STXBP5L,FN1,SEC24D,RIMKLA,SETBP1,LAMC3,GALNT13,FAM81A,MLC1,SATB1,CD7,HSPA12B,PCDHB14,EFEMP1,GALNT1,PRTFDC1,IGF1R,BCHE,ZNF440,PDE10A,ADCY6,VGLL4,NOS3,PAK1,DPYSL5,CDH26,MID2,PCDH10,SLITRK2,PPFIA4,OBSCN,WWC1,SDK1,LHPP,PRDM1,B4GALNT3,TEX9,NEGR1,GRIK4,KIAA0355,FAT1,NXPH4,PTPRN2,PLD1,RNF122,PANK3,XKR4,NEK10,CFH,DOCK1,CELSR3,MORC4,COL18A1,COBLL1,RHPN2,KIF21B,DENND3,TNKS1BP1,RADIL,DOCK2,SEMA6A,PCLO,SP8,COL22A1,UNC13B,TACC2,ZNF521,ZDHHC23,MYH15,MDH1B,MET,SCN2A,POU2F2,PTPN6,VIM,FRK,ZNF569,ARMC4,ZNF93,RANBP2,NRG3,RNF217,TMPRSS9,PTPRS,HGF,LIFR,CTNND2,OR51B5,PCDH18,NECAB2,KLHL13,ARHGEF11,CLGN,RUSC2,APBB1,MCTP2,LRP4,SSX1,CLSTN2,GABRG2,SELL,HBE1,COL4A5,FAM174B,SEL1L3,ARHGAP44,RAB11FIP5,FSD1,FUT9,PRICKLE2,SH3PXD2B,IQGAP3,DLGAP1,CARD6,SYBU,GRID1,ASAP3,MEI1,PRRG1,PRICKLE1,MARS,ARHGAP32,ZFPM2,NPDC1,ILDR2,RERE,CTIF,EBF1,DOCK7,FAT4,L3MBTL4,THSD7B,UACA,KIF21A,IL9R,KIF1B,FILIP1 |
| 6.433e-04 | -7.35 | GSE29618_BCELL_VS_PDC_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_UP | 172 | 31 | 17377 | 1707 |
CXCR5,MYCBP2,CD55,EVL,PDK1,TUBA1A,CKAP2,ST6GAL1,ARID5B,PPFIBP2,RASA3,ADD2,ISG20,PTPRC,IRS2,CD37,ABLIM1,BACH2,PMAIP1,BACE2,MYC,HK2,PIK3C2B,MARCKS,SP140,RRAS2,DDIT3,ATP2B1,SP140L,RAB30,DUSP1 |
| 6.452e-04 | -7.35 | GSE30083_SP1_VS_SP4_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP4_THYMOCYTE_UP | 187 | 33 | 17377 | 1707 |
PAK1,BCL7A,TNK2,TUBA1A,ENO2,AGPAT4,SPATA6,DHCR24,YPEL2,RYR2,PSD3,TDRKH,SATB1,UBTD2,NEDD4,TPK1,ZNF711,IFT81,SLC30A4,PLOD2,SCN1B,XBP1,TSC22D1,PTPRS,LAPTM4B,EPHB6,MARCKS,MYO6,RAB27B,MBOAT2,TMEM120B,SLC45A3,LRP12 |
| 6.452e-04 | -7.35 | GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | 187 | 33 | 17377 | 1707 |
RPS20,MAN2B2,MXI1,ITGA6,SORBS3,RPL34,MCF2L,FAM168A,SGK1,ACVR2A,TOX,EPHB6,ZFP36L2,RPS23,GAB2,RPS13,MID2,TUBA1A,TDRD3,FOXN3,RASA3,PRKCQ,CDC42BPA,FGFR1,BCL11A,GABARAPL1,RANBP2,RPL28,RGS10,KLF5,RPS12,DDIT3,TPT1 |
| 6.452e-04 | -7.35 | GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_UP | MSigDB lists | GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_UP | 187 | 33 | 17377 | 1707 |
SV2B,NBL1,ACVR1,ADD2,PCLO,GAS1,FSTL5,EPDR1,SLC35F1,EPCAM,TUBB4A,IGF1R,FUT9,DNAH6,BACE2,PDE10A,TFAP2A,PRR16,TNFRSF11A,FAM78B,KIAA1211,INTU,PTCH2,DEPTOR,TMEM200C,ATP1B1,ZFPM2,LEPR,PCDHB7,FMO4,KIF1B,CRISPLD1,CRYL1 |
| 6.452e-04 | -7.35 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN | 187 | 33 | 17377 | 1707 |
AVPI1,BMPR2,MSR1,SORBS3,IL13RA1,FAM198B,SLC1A3,SLC12A6,RTN1,CA2,CPVL,IPCEF1,NCEH1,NCAM1,TLR4,ZFP36L2,ITGB7,SLC36A1,KLHL3,MPP1,LRRK2,BNIP3L,LITAF,TTYH2,ATP10D,ARHGAP21,CXCL10,ID3,PTPRJ,MYADM,PRCP,RGS10,TNFRSF1A |
| 6.452e-04 | -7.35 | GO_MESENCHYME_DEVELOPMENT | MSigDB lists | GO_MESENCHYME_DEVELOPMENT | 187 | 33 | 17377 | 1707 |
SEMA6B,ACVR1,OVOL2,SEMA6A,NEDD4,TGFBR3,SEMA4F,EOMES,ACTA2,LRP6,SNAI2,PDGFRB,SEMA6C,EPB41L5,MSX1,DCHS1,YAP1,WNT11,ZFPM2,FGFR1,SMAD3,HEYL,PTK7,WWTR1,HGF,SEMA3C,BMPR1A,BMP4,NRP1,SEMA3A,SIX2,HEY1,MEF2C |
| 6.452e-04 | -7.35 | GSE13306_TREG_VS_TCONV_SPLEEN_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_UP | 187 | 33 | 17377 | 1707 |
DOCK1,ZCCHC24,MLF1,YPEL2,KIAA1217,DYNC1I1,CYP26A1,SIPA1L2,FAM107B,ZDHHC23,TSC22D1,NBEA,SGK1,MAST4,ENAM,MSX1,UROS,MPP1,TCEA3,FGF12,KIAA1324L,CHRNA6,DUSP9,C1R,SESN1,GPC6,ISG20,MAP1B,DOCK7,PTPRJ,BACH2,THBS4,SLFN5 |
| 6.490e-04 | -7.34 | cardiac muscle cell contraction | biological process | GO:0086003 | 38 | 11 | 17256 | 1658 |
SCN5A,KCNN2,SCN1B,CACNB2,ANK2,FGF12,RYR2,PKP2,KCND3,CACNA2D1,GJC1 |
| 6.527e-04 | -7.33 | regulation of cell death | biological process | GO:0010941 | 1701 | 202 | 17256 | 1658 |
TRIM2,ACVR1,GRIK2,DNAJC3,TNFAIP8L2,LILRB1,GATA3,NPM1,STAT5B,PRKCA,AARS,EYA4,STK24,F3,TXNDC5,GSDME,BAG3,RPS6KA2,PMAIP1,HRK,CTTN,EPHB6,TLR4,FANK1,ENO1,SLIT2,POU3F3,PDGFRB,LAMP3,CYP1B1,ATF4,COL4A3,ACVR1C,DCC,WISP3,LRRK2,BNIP3L,DEPTOR,YAP1,AGO4,ROR1,SGK2,SAV1,ARHGEF26,PYCR1,INHBC,GSN,SH3RF1,NCKAP1L,PLK2,RASGRF2,NCOA7,TNFRSF1A,BBC3,ERCC5,NRP1,UNC5B,PPARGC1A,MEF2C,BCL11B,EFNB2,PRKAA2,TYRO3,LATS2,LGALS3,GABRB2,ITGA6,SLK,DHCR24,SLC25A27,TNFRSF10C,GAS1,MECOM,DDIT4,SYCP2,BNIP1,IGF1R,GATA2,MYC,PRELID1,LRP6,BNIP3,STXBP1,ZNF385A,NOS3,HMGCR,PAK1,FGFR4,RPL26,UNC5C,BDNF,ATP5IF1,MSTN,FHL2,OBSCN,STRADB,HIP1,PDE8A,FAM162A,HERPUD1,INHBE,SFN,EPHA3,PRKN,BTC,ID1,COL18A1,NTRK3,DDR1,TIAM2,SCIN,TLR3,ASNS,UNC13B,KMO,MAGEA3,BCL6,DAB2IP,STEAP3,MET,PERP,SNAI2,DOCK8,CTH,IGFBP3,FZD1,PRAME,GAPDH,NOP53,NKX3-2,PREX1,PRKCQ,WNT11,ATF3,ATOH1,CD40,FGFR1,SNCA,IRS2,SMAD3,IKZF3,BEX3,WFS1,MAP3K21,HPGD,TNFSF15,HGF,BMPR1A,ATG5,RETREG1,TNIK,DYRK3,ARHGEF11,PAK5,REL,APBB1,BIK,GAS6,EPHB1,TPD52L1,BMP6,BEX2,MCF2L,PRKCD,SGK3,TFAP2A,SGK1,YBX3,SMAD6,RRAS2,TNFRSF11A,SPRY2,PNMA2,DUSP1,SLC40A1,VAV3,CARD6,MSX1,RAPGEF2,NUGGC,NUAK2,AGAP2,RACK1,ZFPM2,TLR6,MGMT,GPLD1,DKK1,CEBPB,GPR37,ID3,NACC2,TERT,ACER2,MAP2K6,XBP1,PCGF2,BMP4,MAP3K20,DDIT3,FOXA1,TPT1 |
| 6.531e-04 | -7.33 | V$S8_01 | MSigDB lists | V$S8_01 | 233 | 39 | 17377 | 1707 |
LRFN5,INPPL1,PRSS12,CLSTN2,PRDM8,NRXN1,SEL1L3,NEO1,MTUS1,CCNJ,ARHGEF10L,ATXN7L1,KCTD15,EOMES,RALGPS2,IKZF5,SLC10A7,SLC6A15,HRK,FIGN,MYT1,ETV1,SCN3A,B3GALT1,GCNT2,ANK2,ZFPM2,SLC39A14,ADAMTS3,LAMB1,BMP1,INPP5F,SH3BGRL2,ZBTB20,NRP1,SHOX2,SEMA3A,RNF122,MEF2C |
| 6.531e-04 | -7.33 | V$PITX2_Q2 | MSigDB lists | V$PITX2_Q2 | 233 | 39 | 17377 | 1707 |
ACVR1,RASAL2,BMPR2,PLXNA2,NDRG2,PRDM8,CREB5,TNKS1BP1,TRPS1,FOXP2,KCTD15,UNC13B,ABI3BP,LRP6,PRICKLE2,JAKMIP2,HRK,SCN2A,TMEM132E,FIGN,RBMS2,FES,PDLIM7,DPYSL5,RAX,RIN2,MSX1,MEIS2,COL4A3,FZD4,COL4A4,SLITRK5,SLC25A28,PRDM1,HOXA1,BCL11A,BMP4,SHOX2,RNF122 |
| 6.532e-04 | -7.33 | response to acid chemical | biological process | GO:0001101 | 327 | 50 | 17256 | 1658 |
EPHA3,PRKAA2,ACSL1,TRIM16,LDLR,IPO5,ASS1,COL18A1,NTRK3,CHUK,BMP6,CYP26A1,ASNS,TGFBR3,EEF2,ZNF354A,BCHE,SREBF1,ADCY6,PDGFRB,GLDC,DUSP1,FGFR4,GDAP1,SESN2,FZD4,YAP1,ABCC2,WNT11,SESN1,LRAT,MGMT,BAIAP2,CPEB1,DKK1,CEBPB,ID3,GSN,PTK7,ACER2,PEMT,ITGA2,XBP1,SH3BP4,PPARGC1A,TNFSF4,TESC,PTGES,ATP2B4,RRAGD |
| 6.591e-04 | -7.32 | TAATAAT,MIR-126 | MSigDB lists | TAATAAT,MIR-126 | 210 | 36 | 17377 | 1707 |
BCL11B,RASAL2,PLAG1,HECW2,COBLL1,PRDM8,CHUK,DDR1,NOVA1,STK24,TRPS1,AFF2,GHR,MARCH3,DAB2IP,FAM84B,MYT1,ATP2B1,RNF152,PNRC1,FOXN3,ESRRG,JPH1,MAFB,TMEM47,FNDC3A,ZIC1,C11orf45,KLF12,HS3ST3B1,PPARGC1A,NEUROG2,MMP16,MID1,DIRC2,LPP |
| 6.597e-04 | -7.32 | Temperament(PMID:22832960) | GWAS genes | Temperament(PMID:22832960) | 6 | 5 | 2388 | 399 |
MSRB3,CADM2,NRXN1,APBA2,PTPRD |
| 6.631e-04 | -7.32 | BURTON_ADIPOGENESIS_9 | MSigDB lists | BURTON_ADIPOGENESIS_9 | 87 | 19 | 17377 | 1707 |
PLA2G4A,FADS1,LATS2,SKAP2,RECK,HEBP1,CYTH3,FERMT2,TPD52L1,F3,ID3,CSF1,PLK2,PRKCD,ACVR2A,MAOA,GEM,TPM1,CEBPD |
| 6.631e-04 | -7.32 | GO_SYNAPTIC_VESICLE_CYCLE | MSigDB lists | GO_SYNAPTIC_VESICLE_CYCLE | 87 | 19 | 17377 | 1707 |
DOC2A,SYT12,OPHN1,SNAP25,CANX,NRXN1,SYT14,PCLO,SNCA,TRIM9,SH3GL2,UNC13B,CADPS2,PACSIN1,SEPT5,TC2N,STON2,RIMS2,SNPH |
| 6.683e-04 | -7.31 | transmembrane receptor protein serine/threonine kinase activity | molecular function | GO:0004675 | 17 | 7 | 17224 | 1680 |
ACVR2A,BMPR1A,ACVR2B,ACVR1,TGFBR3,BMPR2,ACVR1C |
| 6.710e-04 | -7.31 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | 143 | 27 | 17377 | 1707 |
VAV3,MXI1,ACSL1,RNF145,PNRC1,BNIP3L,NFE2L1,MAFB,SCD,ATF3,CCNG1,DSP,GAS1,TGFBR3,FBXO32,CA2,INSIG1,EEF2,BCL6,MAOA,SEMA3C,PIK3C2B,GEM,ERRFI1,MME,STOM,ATP1A3 |
| 6.717e-04 | -7.31 | V$EVI1_03 | MSigDB lists | V$EVI1_03 | 55 | 14 | 17377 | 1707 |
ADPRHL1,CHCHD7,ADAMTS3,ESRRG,PLAG1,HS3ST5,CREB5,TMEM47,IPCEF1,ZFPM2,PPARGC1A,NRP1,MBNL2,HOXA1 |
| 6.718e-04 | -7.31 | GSE12366_NAIVE_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_NAIVE_VS_MEMORY_BCELL_UP | 165 | 30 | 17377 | 1707 |
GCA,SH3BP2,TTC39B,MSTN,WISP3,GALNT6,SLC39A8,XYLT1,ROR1,PLEKHA1,SATB1,NUDT12,KBTBD11,PEAK1,MYADM,BACH2,MCF2L,GNB4,WDR19,C1orf53,MARCH3,TSPAN13,FIG4,ZNF488,FNBP1L,PTPRE,NEB,DDIT3,KCNB2,ZNF629 |
| 6.719e-04 | -7.31 | GO_PROTEIN_DIMERIZATION_ACTIVITY | MSigDB lists | GO_PROTEIN_DIMERIZATION_ACTIVITY | 1089 | 139 | 17377 | 1707 |
ACVR1,GRIK2,GATA3,LILRB1,NPM1,CADM2,STAT5B,CTBP2,CEBPA,ABAT,RBM11,IKZF2,SNX9,SLC9A7,QPRT,KCNN2,AADAT,HPS1,GSTM3,PTPRE,ENO1,SLIT2,RASGRP1,ATF4,NR6A1,LRRK2,BNIP3L,MEF2B,CR2,PLEKHB1,AHRR,TRIM9,ENPP1,HPSE,ERN1,ADRB1,ERCC5,INPP5F,NEUROG2,CHMP4C,CRYL1,MEF2C,RRAGD,CARS,TYRO3,CELSR1,ZHX3,JDP2,SLK,FBXO4,ADSSL1,GRPEL2,MECOM,SYCP2,PRTFDC1,ZBTB38,PDZD7,FLRT3,MYC,SREBF1,LRP6,BNIP3,JAM2,HMGCR,MID2,TCF24,GSTM4,HOMER2,FASN,LHPP,TAF4B,PLCB1,KHDRBS2,HEYL,CSF1,TESC,NBL1,ID1,ADD2,MAPK4,CHUK,PPP1R9A,CBLN1,ASNS,CHRNA5,DAB2IP,ZNF365,KCNB2,GCA,GARS,FZD4,MVD,KCNH5,NLGN4X,ATF3,ATOH1,JAM3,FGFR1,BCL11A,SMAD3,MSC,IKZF3,WWTR1,ITGA2,HPGD,HGF,BMPR1A,LIFR,MID1,PSPH,HEY1,MXI1,LRP4,BIK,CBS,P2RY1,TPD52L1,BMP6,FOXP2,HMGCS1,BHLHA15,STC2,GHR,TFAP2A,RALGAPA2,PRKG2,GSTM2,NR4A1,CEBPB,ID3,MPP7,NACC2,TERT,XBP1,BMP4,DDIT3,BTRC,STOM,ABCG1 |
| 6.733e-04 | -7.30 | GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP | MSigDB lists | GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP | 195 | 34 | 17377 | 1707 |
SELL,RASD1,SNX9,MCOLN2,CA2,RALGPS2,SLC30A4,MGAT1,PRKCD,TFAP2A,BCL6,MARCKS,PLTP,SYK,TMEM56,FGFR4,ALDH2,PTPN6,CAPN5,C1R,ZDHHC14,CD40,EBF1,ARHGAP21,CD37,NSD1,GSN,ID3,MYADM,ATP7B,GNB4,SQLE,GRIN2D,MEF2C |
| 6.733e-04 | -7.30 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | 195 | 34 | 17377 | 1707 |
DMXL2,ACSL1,LGALS3,BLVRB,LILRB1,KCTD12,CTBP2,CEBPA,IL13RA1,EPB41L3,PRKCD,MARCKS,SNX10,SYK,CKAP4,CEBPD,GAB2,CYP1B1,TBC1D8,GCA,RIN2,ALDH2,RHOQ,SLC36A1,MPP1,MAFB,WARS,CEBPB,EIF4EBP1,SLC2A6,RAB31,CLMN,RNF130,MEF2C |
| 6.733e-04 | -7.30 | GSE38304_MYC_NEG_VS_POS_GC_BCELL_UP | MSigDB lists | GSE38304_MYC_NEG_VS_POS_GC_BCELL_UP | 195 | 34 | 17377 | 1707 |
TNIK,ANKRD13B,ATP8A1,ZCCHC24,GALNT6,GTF2IRD1,RASL11B,BBS9,HECTD2,CA2,RALGPS2,ITGB3,SGK3,ADCY6,MARCKS,ST8SIA1,PACSIN1,MYO6,PAK1,CARD6,MYO10,TNS1,ZDHHC14,MAGI3,ID3,KCNMB4,GYPC,BACH2,PMEPA1,RASGRF2,RNF130,SLFN5,SLC16A10,AMPD1 |
| 6.733e-04 | -7.30 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | 195 | 34 | 17377 | 1707 |
SERINC5,SEMA6B,RGS16,GNG12,AVPI1,CELSR1,SCAMP1,MLF1,XYLT1,SCD,SATB1,INPP1,SLC19A2,NCS1,SKI,UNC13B,OPN3,GSTM3,PDE4D,RIMS2,GAB2,GAPDH,AGPAT4,TGFA,BNIP3L,VIM,CTIF,GABARAPL1,SNCA,PLK2,MAOA,MAPK13,RNF122,SLC16A10 |
| 6.861e-04 | -7.28 | ZBTB21 (zinc finger and BTB domain containing 21) | protein interactions | 49854 | 105 | 22 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,TBC1D1,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,BAIAP2,NAP1L5,NAV1,RALGPS2,SH3BP4,MAP3K21,PPP2R2B,TANC2,KLHL29,OSBPL6,KIF1B,LARP1,GAB2 |
| 6.884e-04 | -7.28 | RAAGNYNNCTTY_UNKNOWN | MSigDB lists | RAAGNYNNCTTY_UNKNOWN | 136 | 26 | 17377 | 1707 |
BDNF,MXI1,ATF4,TUBA1A,BMPR2,ZHX3,CHCHD7,CRIM1,ESRRG,SOX21,PLAG1,AGAP2,ADAMTS6,SATB1,SP8,BCL11A,FOXP2,ID3,ZNF362,NXPH4,DLG2,CERS1,PPARGC1A,IL1RAP,SCN3A,RNF152 |
| 6.884e-04 | -7.28 | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP | MSigDB lists | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP | 136 | 26 | 17377 | 1707 |
DPP10,EPHA3,LCA5,TTC39B,HNF4G,THSD4,DHCR24,ADD2,CADM2,SLC1A3,ARRDC4,FAM110B,RADIL,TNFRSF19,LEPR,GLCE,SPATA9,TECPR1,BCHE,MAP7,PTPRS,TRPC1,SCN2A,TRPC3,ZNF235,PCSK5 |
| 6.892e-04 | -7.28 | guanyl-nucleotide exchange factor activity | molecular function | GO:0005085 | 323 | 50 | 17224 | 1680 |
BTC,FARP1,ARHGEF11,DOCK1,EPS8,PSD3,DOCK3,DENND3,DOCK2,TIAM2,ARHGEF10L,RALGPS2,HPS1,MCF2L,DENND1C,MET,NCAM1,GFRA1,RAPGEF5,DOCK8,RASGRP1,PDGFRB,FGFR4,RIN2,VAV3,ARHGEF28,RAPGEF2,MCF2L2,CYTH3,RAPGEF4,PREX1,SPATA13,OBSCN,FGF17,DOCK5,SERGEF,FGFR1,ARHGEF26,IRS2,DOCK7,RASGRF2,PLEKHG1,ADRB1,GRIN2D,HGF,IQSEC2,DOCK6,DOCK9,DENND5B,ARFGEF3 |
| 6.894e-04 | -7.28 | MFS_dom | interpro domains | IPR020846 | 115 | 23 | 18492 | 1811 |
SV2B,SLC37A1,FLVCR2,SLC2A13,MFSD6,SLC46A3,SLCO3A1,SPNS1,MFSD9,SLC22A17,SLC16A2,SLC22A18,SLC2A6,SLC18B1,SLCO5A1,MFSD4A,SLC16A9,SLC2A12,SLC22A15,SLCO4C1,SLC16A10,DIRC2,SLC43A1 |
| 6.900e-04 | -7.28 | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P4 | 94 | 20 | 17377 | 1707 |
PDK1,MYO10,RAPGEF4,MCTP2,GSTO1,IKZF2,GPLD1,HOPX,GPR15,BACH2,GPRC5B,PLAGL1,SEMA4F,PMAIP1,SH3BGRL2,CTTN,SLC22A15,NRP1,NEB,RRAGD |
| 6.931e-04 | -7.27 | PROTEIN_KINASE_TYR | prosite domains | PS00109 | 94 | 21 | 12060 | 1278 |
EPHA3,FGFR4,TYRO3,FER,TNK2,NEK10,OBSCN,NTRK3,ROR1,EPHB1,PEAK1,DDR1,FRK,FGFR1,FGR,IGF1R,PTK7,MET,SYK,FES,PDGFRB |
| 6.933e-04 | -7.27 | GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 1870 | 224 | 17377 | 1707 |
NMNAT3,MVK,ACVR1,ADAL,DUSP8,PDE1B,FGF13,PTPN21,STAT5B,PRKCA,CACNB4,ABHD4,ABHD6,STK24,EYA4,QPRT,MOK,PPM1E,TYMP,TGFBR3,RPS6KA2,SERINC2,NDUFB8,EPHB6,PTPRE,TLR4,ENO1,RASGRP1,PRKACB,PDGFRB,NKX2-1,TNK2,MARK1,SMAD9,ACVR1C,DNAJC6,LRRK2,ROR1,ACVR2B,FGF17,SGK2,NT5DC2,DYRK1B,AK1,ENPP1,ENPP6,PLK2,RASGRF2,ALDOA,ERN1,PIK3C2B,MAPK13,INPP5F,OXTR,CRYL1,MEF2C,PRKAA2,TYRO3,LATS2,MOCOS,INPPL1,PTPRD,UBASH3B,SLK,ISYNA1,ADSSL1,TNFRSF19,PGAP1,DOK5,EFEMP1,PRTFDC1,IGF1R,ADCK1,PDE10A,MYC,PRKG1,ADCY6,ALPK1,NCAM1,MAST4,GFRA1,HMGCR,FGFR4,PAK1,FADS1,IL17RD,RHOQ,PNP,DUSP9,CALCRL,STRADB,OBSCN,PDE8A,LHPP,CDC42BPA,PLCB1,MAPKAPK2,PKN3,HK2,MPP2,PTPRN2,PLD1,PANK3,AMPD1,EPHA3,PLA2G4A,BTC,NUDT10,NEK10,RASAL2,IL15,LPCAT2,CHUK,MAPK4,NTRK3,GRK6,LPIN3,NUDT12,DDR1,PIBF1,CDS1,SPEG,TLR3,IDI1,CDC14B,KMO,RPS6KL1,ALDOC,MYO3B,ACVR2A,DAB2IP,PDE4D,FHIT,MET,IGFBP3,FER,SSH3,MYLK3,GAPDH,GARS,PDK1,PFKFB2,ADM2,PTPRU,MVD,PTPN6,KCNH5,PANK1,FGF12,ADCY1,PRKCQ,WNT11,ATP1B1,FRK,MAGI3,FGFR1,TPK1,SNCA,IRS2,PTPRJ,PRKCB,PTK7,PEMT,ABI3,DUSP19,INPP4B,PTPRS,BMPR1A,MAPK10,MBOAT2,PSPH,MAST1,TNIK,SERINC5,DYRK3,BMPR2,ENO2,GAS6,EPHB1,PKN1,INPP1,PPP2R3A,GHR,PRKCD,SGK3,PRKG2,SGK1,FIG4,IQGAP3,SYK,SMPDL3A,FES,DUSP1,PFKFB4,PPP1R3D,MPP1,RAPGEF2,PTPN13,AGPAT4,OGDHL,NUAK2,AK4,RASA3,CTTNBP2NL,GUCY1A2,PEAK1,SMPDL3B,GPLD1,PTPRC,TRIB3,FGR,MAP2K6,AKT3,SRD5A3,PGM2L1,NEK11,GRIN2D,DLG2,PIP5KL1,HK1,BMP4,LRRK1,CMPK2,BTRC |
| 6.934e-04 | -7.27 | response to oxygen-containing compound | biological process | GO:1901700 | 1458 | 176 | 17256 | 1658 |
ACSL1,TRIM16,LDLR,LILRB1,ASS1,GATA3,STAT5B,ITPR2,ABAT,STK24,FBXO32,TGFBR3,TLR4,TSHR,SLIT2,PRKACB,PDGFRB,GLDC,CYP1B1,GDAP1,SESN2,ATF4,ACVR1C,LRRK2,YAP1,PRKAR2B,ABCC2,ACVR2B,PLEKHA1,SESN1,GNAI1,GSN,ENPP1,INSIG1,GNB4,ERN1,TNFRSF1A,MAPK13,OXTR,TPM1,TNFSF4,PPARGC1A,RRAGD,MEF2C,PRKAA2,GNG12,INPPL1,HID1,ATP6V1E2,TNFRSF10C,MLC1,DDIT4,EEF2,CA2,IGF1R,ZNF354A,BCHE,SREBF1,LRP6,INAVA,ADCY6,BNIP3,STXBP1,CHRM3,HMGCR,NOS3,PAK1,FGFR4,RHOQ,MSTN,HOMER2,EDEM3,RYR2,CALCRL,SDK1,PLCB1,CPEB1,BAIAP2,MMP15,MAPKAPK2,SH3BP4,RAB31,PTPRN2,HOXD13,TRPC3,TESC,SMYD3,EPHA3,PRKN,ID1,SORBS1,IL15,COL18A1,CHUK,NTRK3,CYP26A1,TXNRD3,ASNS,UNC13B,KMO,DAB2IP,PDE4D,FER,COL6A2,FZD4,PFKFB2,ADCY1,WNT11,CD40,SNCA,IRS2,CXCL10,PTK7,EIF4EBP1,PEMT,ITGA2,PAM,RGS10,HPGD,KLF5,PSPH,PLSCR4,IPO5,SELL,GAS6,BMP6,NKX6-1,FOXP2,RAB11FIP5,HMGCS1,DSG2,PRKCD,GHR,STC2,KLF9,ERRFI1,PCK2,ESD,GFI1,TNFRSF11A,ATP2B1,DUSP1,TRPM4,PXN,NR4A1,NUGGC,RAPGEF2,LITAF,MARS,RACK1,TLR6,ILDR2,LRAT,MGMT,DKK1,GPLD1,CEBPB,ID3,TRIB3,FBN1,MAP2K6,GNAO1,ACER2,CTSV,XBP1,PCGF2,CMPK2,CERS1,TBC1D4,KIF1B,PTGES,FOXA1,LARP1,ATP2B4,CACNA2D1,ATP1A3 |
| 6.936e-04 | -7.27 | GO_SINGLE_ORGANISM_CELL_ADHESION | MSigDB lists | GO_SINGLE_ORGANISM_CELL_ADHESION | 444 | 65 | 17377 | 1707 |
IL15,GATA3,LILRB1,PKP2,STAT5B,NRXN1,COL14A1,RADIL,DOCK2,CTNNA2,EOMES,ITGB3,COL19A1,PERP,DOCK8,CYP1B1,ITGB7,FER,PTPRU,FZD4,PTPN6,PREX1,NLGN4X,BATF,DSP,JAM3,SMAD3,NCAM2,LAMB1,ATG5,TNFSF4,CTNND2,BCL11B,TYRO3,RUNX2,FN1,BVES,FZD8,CD276,GAS6,SATB1,CD7,IL18R1,NEDD4,SLC7A11,CNTN4,DSG2,LRP6,JAM2,STXBP1,ZFP36L2,SYK,PODXL2,MAFB,FERMT2,FNDC3A,PEAK1,LEPR,NEGR1,PTPRC,CEBPB,THBS4,FAT1,CDH2,NPHP1 |
| 6.939e-04 | -7.27 | GO_SODIUM_CHANNEL_REGULATOR_ACTIVITY | MSigDB lists | GO_SODIUM_CHANNEL_REGULATOR_ACTIVITY | 32 | 10 | 17377 | 1707 |
FGF13,SCN1B,FGF12,SGK3,SGK1,PKP2,SGK2,NEDD4,ATP2B4,GPLD1 |
| 6.939e-04 | -7.27 | KASLER_HDAC7_TARGETS_2_DN | MSigDB lists | KASLER_HDAC7_TARGETS_2_DN | 32 | 10 | 17377 | 1707 |
SESN2,TACC2,ZCCHC24,STC2,MPP2,BBC3,TNFRSF19,SEMA6A,TSPAN17,PYCR1 |
| 6.961e-04 | -7.27 | V$FOXO3_01 | MSigDB lists | V$FOXO3_01 | 226 | 38 | 17377 | 1707 |
BCL11B,PCDH18,CHCHD7,PLAG1,TJP1,NTRK3,COLEC10,LCP2,IKZF2,HMCN1,NEDD4,DDIT4,FOXP2,ZNF362,FRY,CPVL,STC2,ZNF521,GFRA1,PDGFRB,NKX2-1,BDNF,BCL7A,MEIS2,FGF12,PRDM1,MBNL2,SKAP1,KLF12,SH3RF1,PELI2,TIGD4,DLX2,SEMA3A,SHOX2,MAPK10,NR3C2,CACNA2D1 |
| 6.961e-04 | -7.27 | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_DN | 226 | 38 | 17377 | 1707 |
RHOBTB1,SYT12,C1orf226,COL4A5,ABAT,TPD52L1,NAV1,IGF1R,PMAIP1,KAZN,FRAS1,MPPED2,SGK3,ATRNL1,AFAP1L2,CPE,GFRA1,BOD1,FZD1,SUSD3,THSD4,SYBU,DEPTOR,HIP1,ATP11A,CCNG1,FRK,SMPDL3B,TSKU,DDAH1,MAP2,GNB4,CCNA1,RAB31,HPGD,SUSD4,TTC39A,ATP2B4 |
| 6.979e-04 | -7.27 | PODAR_RESPONSE_TO_ADAPHOSTIN_DN | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_DN | 17 | 7 | 17377 | 1707 |
SCD,CXCL10,IDI1,INSIG1,MSMO1,DHCR7,HK2 |
| 6.979e-04 | -7.27 | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN | MSigDB lists | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN | 17 | 7 | 17377 | 1707 |
TRIB3,MPDZ,DBP,ACVR1,SESN1,HERPUD1,RERE |
| 6.979e-04 | -7.27 | TOMIDA_METASTASIS_DN | MSigDB lists | TOMIDA_METASTASIS_DN | 17 | 7 | 17377 | 1707 |
GARS,ENO2,LGALS3,NR4A1,EIF1,SYBU,WARS |
| 6.979e-04 | -7.27 | GO_SYNAPTIC_VESICLE_ENDOCYTOSIS | MSigDB lists | GO_SYNAPTIC_VESICLE_ENDOCYTOSIS | 17 | 7 | 17377 | 1707 |
PACSIN1,SH3GL2,CANX,SYT12,STON2,SNCA,OPHN1 |
| 6.979e-04 | -7.27 | GO_RESPONSE_TO_MUSCLE_ACTIVITY | MSigDB lists | GO_RESPONSE_TO_MUSCLE_ACTIVITY | 17 | 7 | 17377 | 1707 |
RYR2,PRKAA2,PPARGC1A,MSTN,ADSSL1,AKAP5,ITGA2 |
| 6.979e-04 | -7.27 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_PHOSPHATASE_ACTIVITY | 17 | 7 | 17377 | 1707 |
PTPRC,PTPRS,PTPRN2,PTPRU,PTPRE,PTPRD,PTPN6 |
| 6.993e-04 | -7.27 | human chr6q21 | chromosome location | human chr6q21 | 63 | 13 | 26185 | 1967 |
BVES-AS1,POPDC3,WISP3,BVES,FAM229B,CRYBG1,TUBE1,PRDM1,MARCKS,FIG4,ATG5,SESN1,SLC16A10 |
| 6.994e-04 | -7.27 | GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN | 158 | 29 | 17377 | 1707 |
MYO1D,FARP1,PLSCR4,SORBS1,PXN,IL15,CRIM1,PTPN13,XYLT1,TNFSF13B,SPATA13,ADD2,ADAMTS6,GDPD5,SMPDL3B,NEDD4,GALNT3,ENTPD1,FGR,ZBTB38,IKZF3,EOMES,PIK3AP1,SH3RF1,PLXDC2,TRPC1,LRRK1,SPRY2,ATP6AP1L |
| 6.994e-04 | -7.27 | GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | 158 | 29 | 17377 | 1707 |
SERINC5,GNG12,VAV3,TMEM67,LCA5,EIF4E3,TMEM65,DCC,NR4A1,MPP1,AGPAT4,CYTH3,TMTC4,RYR2,STAT5B,SFXN3,HERPUD1,EPCAM,GRHL1,AKAP7,P4HA1,MARCH3,SH3BGRL2,DYNC2H1,POU2F2,AGL,FRMD5,ATP2B1,SLC43A1 |
| 7.015e-04 | -7.26 | endocytosis | biological process | GO:0006897 | 540 | 75 | 17256 | 1658 |
DNM3,CACNG3,PRSS12,DOCK1,LDLR,MSR1,LILRB1,JCHAIN,CANX,SNX9,DNER,RAC3,DOCK2,ZFYVE9,TXNDC5,ITGB3,GULP1,CTTN,PACSIN1,SNX10,TNK2,ANK2,DNAJC6,LRRK2,NLGN4X,GRK3,SNCA,GSN,ENPP1,WIPF3,NCKAP1L,INPP5F,STON2,TYRO3,MRC2,INPPL1,SCART1,ATP9A,LRP4,OPHN1,GAS6,MLC1,NEDD4,GATA2,PRKCD,GHR,LRP6,MARCH3,LOXL4,DENND1C,MYO6,SYK,LRP3,LRP12,SNX7,PDLIM7,PAK1,RIN2,VAV3,RHOQ,MYO10,VLDLR,PACSIN3,HIP1,CALCRL,SNAP25,LEPR,BAIAP2,MAPKAPK2,FGR,SH3GL2,FCHO2,SH3BP4,RAB31,FNBP1L |
| 7.058e-04 | -7.26 | JIANG_HYPOXIA_NORMAL | MSigDB lists | JIANG_HYPOXIA_NORMAL | 297 | 47 | 17377 | 1707 |
MVK,MXI1,ENO2,ZNF395,MLF1,BLVRB,NDRG2,IGF2BP2,SCD,CANX,SNX9,KREMEN1,RSL24D1,MSMO1,ALDOC,STC2,BNIP3,MARCKS,SNX10,IGFBP3,DUSP1,PFKFB4,SESN2,SLC3A2,PTPRU,FAM84A,FASN,BNIP3L,TCEA3,AK4,FEZ1,YAP1,ASPH,SERGEF,FAM162A,TSKU,HLF,RPL12,PLOD2,MAP2K6,SQLE,MAOA,P4HA1,GRB10,DHCR7,IL9R,STOM |
| 7.071e-04 | -7.25 | GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 101 | 21 | 17377 | 1707 |
TRPM4,JDP2,GATA3,CEBPA,RARRES2,ZFPM2,SAV1,CEBPB,SMAD3,ENPP1,TRIB3,INSIG1,GATA2,C1QL4,WWTR1,XBP1,KLF5,SH3PXD2B,DDIT3,SNAI2,ZNF385A |
| 7.104e-04 | -7.25 | GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 188 | 33 | 17377 | 1707 |
PHACTR3,TTC39B,JDP2,SELL,ADAMTS6,STAT5B,SLC19A2,TXNRD3,SLC22A17,EOMES,GRHL1,TRIM3,KLF9,DYNC2H1,GFI1,ITGB7,STAT4,CYTH3,LRRK2,LRMP,ST6GALNAC3,BATF,FBXO36,SESN1,CTIF,CAMK2N1,IKZF3,SH3RF1,P4HA1,INPP5F,DLX2,CSRP2,RRAGD |
| 7.104e-04 | -7.25 | GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_UP | MSigDB lists | GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_UP | 188 | 33 | 17377 | 1707 |
CXCR5,FAM171B,NMNAT3,EHHADH,IGFBP6,FGF13,ABAT,EOMES,GRHL1,CDC14B,GPR155,ZNF518B,TNFRSF11A,PTCH2,ATF4,RNF145,TMEM65,CLYBL,LRRK2,TMTC4,RASA3,PLCB1,STEAP1,HOXA1,SNCA,SVIL,ARHGAP28,CMPK2,CTTNBP2,TBC1D4,PURG,HEY1,MAST1 |
| 7.104e-04 | -7.25 | kinase binding | molecular function | GO:0019900 | 688 | 93 | 17224 | 1680 |
EPHA3,PRKN,RHOD,DNAJC3,PKP2,ADD2,NPM1,CEBPA,NTRK3,MAPK4,CTBP2,DDR1,RAC3,SKI,RND2,AKAP7,DACT1,NBEA,DAB2IP,JAKMIP2,MARCKS,EPHB6,MET,JAKMIP3,WWC2,IL1RAP,PDGFRB,GAB2,ATF4,PFKFB2,ANK2,PTPN6,PRKAR2B,ATP1B1,ROR1,DSP,TTC28,FGFR1,WARS,SMAD3,CAMK2N1,IRS2,NRG3,PTPRJ,GPRC5B,PRKCB,MAP3K21,DUSP19,DIRAS1,NRP1,CACUL1,FRMD5,TYRO3,SCN5A,KIZ,GRB14,RHOBTB1,LRP4,GAS6,PKN1,EPHB1,EEF2,IGF1R,PRKCD,GHR,SREBF1,ACTA2,ADCY6,ERRFI1,SPRY2,SYK,MOB1B,FGFR4,RHOQ,RYR2,WWC1,PDE8A,RACK1,SKAP1,PTPRC,MAPKAPK2,CEBPB,TRIB3,FGR,RND3,GCSAM,MAP2K6,LAPTM4B,DLG2,MYOM2,CDH2,SFN,PKIA |
| 7.116e-04 | -7.25 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_6H_ACT_CD4_TCELL_DN | 173 | 31 | 17377 | 1707 |
PHACTR3,GCA,MXI1,ABCC4,SLC27A2,CYTH3,TNFSF13B,CHRNA6,TDRKH,PLS1,LACC1,FRK,ABHD6,NEDD4,DDIT4,OTUD1,GALNT1,ID3,TIFA,GBP1,MAP9,FAM107B,PAM,PGM2L1,TMEM117,SGK1,HS3ST3B1,PDE4D,IPCEF1,TNFSF4,ZFP36L2 |
| 7.144e-04 | -7.24 | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 661 | 90 | 17385 | 1698 |
DMXL2,MYCBP2,THOC5,RASAL2,DOCK1,CNTNAP3,PLEKHA5,COL18A1,ADD2,GRK6,LCP2,DENND3,ANKRD42,EOMES,UNC13B,SLC22A17,CNKSR3,SLC22A18,RPS6KL1,ITGB3,ETV1,NEB,MARK1,ABCC4,MVD,TCEAL3,TNS1,SAV1,DSP,GSN,ZNF93,PTPRJ,KPNA3,BACH2,ATP7B,WWTR1,PLEKHG1,NCOA7,TNFSF15,DSEL,DNHD1,PSPH,MAST1,CARS,TNIK,TMEM63C,SCN5A,ZHX3,ITPRIP,TJP1,ZNF215,FAM174B,NEDD4,MTUS1,ABLIM1,TECPR1,SOAT2,FRAS1,PCBP4,SMTN,PRKG1,LRP6,RALGAPA2,ADCY6,TRIM3,FAR2,GPR161,CAND2,PARP9,HMGCR,EPB41L5,PTCH2,FGFR4,SH3BP2,PNP,MYO10,MSTN,NR4A1,OBSCN,SDK1,ATP11A,ZFPM2,DAGLA,FGR,FAT1,MAP2K6,CDH17,CDH2,SIX2,SNPH |
| 7.151e-04 | -7.24 | positive regulation of transferase activity | biological process | GO:0051347 | 663 | 89 | 17256 | 1658 |
EPHA3,NEK10,ACSL1,AVPI1,FGF13,NTRK3,LCP2,SNX9,PIBF1,DDR1,PPP1R9A,STK24,TLR3,CDC14B,ITGB3,SERINC2,DAB2IP,EPHB6,MET,TLR4,PRKACB,RASGRP1,PDGFRB,FZD4,PFKFB2,TGFA,LRRK2,ADCY1,PRKAR2B,PRKCQ,WNT11,ACVR2B,ROR1,CD40,FGFR1,SNCA,NRG3,GPRC5B,NCKAP1L,ERN1,MAP3K21,DUSP19,TNFSF15,HGF,DIRAS1,MAPK10,CACUL1,TENM1,TYRO3,SERINC5,TNIK,PAK5,FZD8,SLK,GAS6,PKN1,EPHB1,TPD52L1,IGF1R,MYC,PRKCD,GHR,ADCY6,INAVA,AFAP1L2,IQGAP3,TNFRSF11A,SYK,SPRY2,PAK1,FGFR4,VAV3,RAPGEF2,VLDLR,STRADB,DUSP9,AGAP2,ARRDC4,TLR6,DKK1,MAPKAPK2,PTPRC,TRIB3,FGR,CSF1,MAP2K6,BMP4,MAP3K20,ATP2B4 |
| 7.177e-04 | -7.24 | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | 566 | 79 | 17385 | 1698 |
MVK,ACVR1,ZNF311,NPM1,CHUK,NTRK3,GRK6,PRKCA,DDR1,CBLN1,STK24,TXNRD3,SPEG,ZNF827,RPS6KA2,RPS6KL1,ACVR2A,MET,DNAH5,OR2W3,MYT1,PRKACB,PDGFRB,TNK2,EML6,PDK1,TGFA,ACVR2B,ATP1B1,FGFR1,CAMK2N1,AK1,PRKCB,PLK2,PTK7,MAPK13,ERCC5,PIK3C2B,KLF5,BMPR1A,LIFR,LATS2,KLF8,TNIK,MRC2,STOX2,PLAG1,ARHGAP44,NEO1,CHN2,IGF1R,AFF2,SGK1,SYK,FES,PAK1,FGFR4,BCL7A,IL17RD,CRIM1,GSTM4,ARID5B,AK4,PDE8A,CDC42BPA,PALLD,DAGLA,MAPKAPK2,TEX15,NSD1,TRIB3,FGR,CECR2,AKT3,MAP2K6,HK2,HK1,TBC1D4,DDIT3 |
| 7.184e-04 | -7.24 | transport | biological process | GO:0006810 | 4204 | 458 | 17256 | 1658 |
DOC2A,THOC5,SIDT1,FLVCR2,GRIK2,PRSS12,ATP8A1,DNAJC3,LDLR,VAMP8,MCOLN3,GATA3,NPM1,STAT5B,SNX9,RAC3,SLC9A7,NCS1,PCDH7,TRPS1,TXNDC5,PMAIP1,SLC16A2,SLC22A18,PPFIA2,RAB26,KCNS3,SERINC2,NDUFB8,TMED9,TMEM37,COG3,PACSIN1,PLTP,TBC1D8,GDAP1,ERGIC1,KLHL3,SLC9C1,WLS,EXOC6B,TGFA,LRRK2,DNAJC6,LRMP,BNIP3L,SLC25A28,ABCC2,KCND3,ACVR2B,ZDHHC14,CA13,SFXN1,SLC7A1,ENPP1,WIPF3,NCKAP1L,ATP7B,ALDOA,BBC3,MFSD4A,INPP5F,NRP1,SCN5A,TMEM63C,INPPL1,MRC2,TBC1D1,GABRB2,SCN8A,OPHN1,SLC25A27,SLC36A4,SLC1A3,APBA1,DYNC1I1,BBS9,TTC30B,RPL13A,GRPEL2,MCOLN2,BNIP1,SLC7A11,CACNB2,MYC,PRELID2,PRELID1,SLC16A9,LMAN2,CADPS2,LOXL4,DENND1C,AGL,STXBP1,FAM155A,RPS23,LRP12,CHRM3,RIMS2,RPL26,QSOX1,SLC37A1,PNP,KCNQ3,MYO10,TBC1D8B,SLC36A1,PLEKHA8,VLDLR,RAPGEF4,PACSIN3,RYR2,TTYH2,HIP1,TTC30A,CALCRL,PLS1,PEX5L,NPC2,SNAP25,ARRDC4,CLN5,CACHD1,TMCO3,VPS37D,SH3GL2,RPL28,CECR2,WDR19,CDH17,DYNC2LI1,SELENOM,LAPTM4B,TRPC3,PLA2G4A,FRMPD3,DNM3,SCAMP1,RHOD,MYO1B,MSR1,ADD2,NRXN1,LCP2,DDR1,SLC19A2,TBC1D30,ZFYVE9,CHRNA5,ALDOC,STARD4,SCRN1,FAM155B,ARL4D,RAB27B,SYNGR3,SNX10,ATP6AP1L,SCN3A,KCNB2,FZD4,CYB5R2,SFXN4,KCNH5,TRAM1L1,NLGN4X,ATP1B1,RAB38,DSP,ASPH,TBC1D16,ATP10D,SNCA,GJC1,SLC39A14,ARHGAP21,PRKCB,ASIC1,PAM,STON2,RAB30,THOC3,DENND5B,RPS20,ANO10,MYO1D,SERINC5,ATP9A,CLBA1,IPO5,KIF5C,GAS6,GABRR2,SLC12A6,NDFIP2,SELENOP,KCNC4,NEDD4,LRRC55,SOAT2,GPR155,BHLHA15,GHR,SGK3,SLC6A15,DYNC2H1,MYO6,TBC1D9,TRPM4,PDLIM7,VEGFC,TMC7,SLC40A1,VAV3,ARAP2,LCA5,RAB6B,CACNA1E,RPL21,ZDHHC15,RASA3,ATP11A,GPLD1,PTPRC,FGR,RPL12,OSBPL5,XBP1,SLCO5A1,GRIN2D,JHY,DDIT3,ATP2B4,TPT1,SLC43A1,ATP1A3,EXPH5,CACNG3,ACSL1,FGF13,SYT12,KIF5A,JCHAIN,LILRB1,ITPR2,SLC2A13,SYT14,CACNB4,NUP62CL,DNER,SLCO3A1,ADPRHL1,KCNAB1,SEC16B,KCNN2,SLC10A7,ITGB3,TRPC1,LIN7A,CNNM2,SLC2A12,CTTN,MYRIP,TLR4,IL1RAP,RASGRP1,TNK2,GPM6A,CD55,KCNIP3,SESN2,SLC3A2,ABCC4,ANK2,ATOX1,JPH1,COTL1,SGK2,GRK3,SPNS1,TRIM9,GSN,KCNMB4,HPSE,OXTR,APBA2,TC2N,SLC9B1,CHMP4C,PCSK5,PRKAA2,KCNV1,TYRO3,SV2B,FN1,LGALS3,STXBP5L,HID1,SEC24D,BVES,SCART1,STXBP6,ATP6V1E2,MLC1,PGAP1,SPIRE1,EEF2,SLC30A4,CA2,ABCA5,GATA2,FRAS1,RPS11,LRP6,BNIP3,NIPAL2,SLCO4C1,LRP3,CKAP4,SNX7,PAK1,NDUFA4L2,HBG2,ATP5IF1,RHOQ,SLC27A2,PPFIA4,STRADB,SLC46A3,STEAP1,HERPUD1,BAIAP2,TBC1D2,MAPKAPK2,KCNK15,GRIK4,FCHO2,MFSD2A,SLC2A6,SH3BP4,RAB31,HK2,PTPRN2,PLD1,FNBP1L,OSBPL6,TESC,SIX2,MME,SFN,CREB3L2,PRKN,AKAP5,DOCK1,SLC7A2,CANX,DENND3,PCLO,CBLN1,DOCK2,SCIN,CD53,UNC13B,PDZD8,SLC22A17,FABP6,ZDHHC6,BCL6,ZDHHC23,STEAP3,PROS1,GULP1,POU2F2,SCN2A,HSPA2,RPS13,GCA,ANTXR2,TUBA1A,CSN2,NOP53,LRRC8B,SLC39A8,PTPN6,ACO1,CHRNA6,SYNJ2BP,RARRES2,FRK,RANBP2,IFT81,PTPRJ,KPNA3,BACH2,KCNG1,HGF,DISP1,SEPT5,SLC6A9,LRP4,TNFSF13B,GABRG2,SELL,IGF2BP2,HBE1,SFXN3,ARHGAP44,MCU,RPL34,RAB11FIP5,SLC35F1,KCNJ4,MAP1A,SCN1B,PRKCD,EHD3,KCNMB3,SGK1,TRIM3,MARCH3,IPCEF1,SYK,SLC45A3,ATP2B1,PCSK6,RIN2,RAB3B,CYTH3,SYBU,ASAP3,GRID1,PRICKLE1,AGAP2,PHACTR2,TLR6,LEPR,ILDR2,HOMER3,MAP1B,RERE,DOCK7,ICA1,MFSD9,PRCP,SLC7A5,SLC18B1,DLG2,RPL4,SLC22A15,RPS12,SLC1A5,TBC1D4,KIF1B,SLC16A10,CACNA2D1,ABCG1,STOM,SNPH |
| 7.198e-04 | -7.24 | phosphotransferase activity, alcohol group as acceptor | molecular function | GO:0016773 | 785 | 104 | 17224 | 1680 |
EPHA3,BTC,NEK10,MVK,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,PFKFB2,KCNH5,LRRK2,PANK1,PRKCQ,ACVR2B,FGF17,ROR1,SGK2,FRK,GRK3,FGFR1,IRS2,DYRK1B,PRKCB,PTK7,PLK2,ERN1,MAP3K21,MAPK13,PIK3C2B,HGF,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,EFEMP1,IGF1R,PIK3AP1,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FES,PFKFB4,FGFR4,PAK1,HYKK,CRIM1,EFNA3,NUAK2,OBSCN,STRADB,CDC42BPA,PEAK1,MAPKAPK2,FGR,PKN3,PELI2,AKT3,MAP2K6,HK2,NEK11,PGM2L1,PIP5KL1,HK1,LRRK1,MAP3K20,PANK3 |
| 7.238e-04 | -7.23 | GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | MSigDB lists | GO_RESPONSE_TO_ENDOGENOUS_STIMULUS | 1409 | 174 | 17377 | 1707 |
CGN,ACVR1,ACSL1,PDE1B,TRIM16,GATA3,ASS1,STAT5B,ITPR2,ABAT,AARS,F3,SKI,FBXO32,TGFBR3,AKAP7,CHRDL1,GSTM3,TSHR,SLIT2,PRKACB,PDGFRB,NKX2-1,SESN2,GCNT2,SMAD9,ACVR1C,NR6A1,GJB2,LRRK2,PRKAR2B,ABCC2,ACVR2B,KCND3,FGF17,GNAI1,GSN,ENPP1,ATP7B,GNB4,BMP1,OXTR,TNFSF4,PPARGC1A,MAGI2,RRAGD,MEF2C,PRKAA2,LATS2,GNG12,INPPL1,RUNX2,FN1,GABRB2,DHCR24,ATP6V1E2,CA2,IGF1R,ZNF354A,EEF2,SLC7A11,BCHE,FLRT3,SREBF1,LRP6,ADCY6,GRIP1,AGL,FGFR4,EPB41L5,PAK1,RHOQ,MSTN,MGST3,VLDLR,FHL2,RYR2,SDK1,CPEB1,BAIAP2,MMP15,PMEPA1,HEYL,SH3BP4,RAB31,TRPC3,SMYD3,PLA2G4A,ID1,SORBS1,AKAP5,RBFOX2,NTRK3,CHUK,ZFYVE9,ASNS,CHRNA5,ACVR2A,DAB2IP,PDE4D,SNAI2,FZD1,TRDMT1,FER,UROS,PTPRU,FGF12,ADCY1,CHRNA6,PRKCQ,ASPH,FGFR1,SNCA,SMAD3,IRS2,EIF4EBP1,PEMT,ITGA2,PAM,HPGD,GRB10,BMPR1A,NR3C2,PSPH,HEY1,ROBO2,BMPR2,ESRP1,LRP4,IPO5,SELL,GABRG2,BMP6,NEDD4,NKX6-1,HMGCS1,DSG2,PRKCD,STC2,GHR,GTF2F2,SGK1,KLF9,ERRFI1,SMAD6,SYK,ATP2B1,DUSP1,MSX1,PXN,GSTM2,KDM5B,HNF4G,NR4A1,RAPGEF2,ESRRG,FERMT2,LEPR,MGMT,GPLD1,CEBPB,GALNT3,TRIB3,FBN1,PLOD2,GNAO1,XBP1,BMP4,TBC1D4,FOXA1,ATP2B4,DDIT3,ATP1A3,ABCG1 |
| 7.238e-04 | -7.23 | GIGYF1 (GRB10 interacting GYF protein 1) | protein interactions | 64599 | 92 | 20 | 17029 | 1718 |
CGN,LATS2,PHLDB2,RASAL2,TBC1D1,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,SH3BP4,GRB10,TANC2,OSBPL6,KIF1B,LARP1,GAB2 |
| 7.302e-04 | -7.22 | identical protein binding | molecular function | GO:0042802 | 1670 | 201 | 17224 | 1680 |
MVK,ACVR1,GRIK2,LDLR,PPFIBP2,ASS1,LILRB1,JCHAIN,NPM1,CEBPA,CTBP2,CADM2,ABAT,SNX9,RBM11,IKZF2,SLC9A7,QPRT,TYMP,KCNN2,AADAT,GRHL1,CFHR1,ITGB3,GSTM3,PACSIN1,ENO1,SLIT2,RASGRP1,GLDC,ATL1,TNK2,NR6A1,CAP2,GJB2,LRRK2,BNIP3L,DESI1,CR2,SAV1,PYCR1,TRIM9,ENPP1,NCAM2,ALDOA,ERN1,TNFRSF1A,BMP1,ERCC5,INPP5F,TPM1,CHMP4C,CRYL1,CARS,FN1,ZHX3,UBASH3B,FBXO4,SLK,GPSM2,ADSSL1,GRPEL2,IL17D,ZBTB38,PRTFDC1,IGF1R,PIK3AP1,PDZD7,BCHE,FLRT3,C1QL4,LRP6,BNIP3,VSIR,STXBP1,HMGCR,MID2,ATP5IF1,CDH26,MSTN,STAT4,GSTM4,HOMER2,FASN,FHL2,HIP1,RYR2,SDC3,MAFB,LHPP,RABAC1,CDC42BPA,SDK1,PLCB1,KHDRBS2,BAIAP2,PLEKHH2,SH3GL2,GSTO2,FCHO2,CSF1,HEYL,SH3BP4,CDH2,TESC,SFN,NBL1,PRKN,AMOTL1,ID1,PLXNA2,ADD2,CHUK,KCTD12,MAPK4,CBLN1,PPP1R9A,CTNNA2,RIDA,TLR3,ASNS,KCTD15,BCL6,DAB2IP,MARCKS,FHIT,MET,CTH,GCA,GAPDH,GARS,PTPRU,NOP53,FZD4,MVD,NLGN4X,VIM,ATF3,CBY1,ETNPPL,JAM3,FGFR1,WARS,SNCA,SMAD3,PTPRJ,IKZF3,GYPC,BEX3,TDO2,GBP1,RBPMS2,ABI3,WWTR1,MAP3K21,P4HA1,HPGD,SOHLH2,HGF,BMPR1A,MID1,KCTD1,PSPH,TENM1,ROBO2,GRB14,LRP4,CBS,TPD52L1,MCU,FOXP2,FSD1,HMGCS1,BHLHA15,STC2,GHR,TFAP2A,PRKG2,PHYKPL,SEPT3,ESD,SMAD6,SLC40A1,USP2,GSTM2,RACK1,TLR6,HOXA1,LEPR,HOMER3,PTPRC,CEBPB,TERT,NACC2,FBN1,CLDN12,XBP1,LRRK1,DDIT3,ABCG1,STOM |
| 7.317e-04 | -7.22 | HOOI_ST7_TARGETS_UP | MSigDB lists | HOOI_ST7_TARGETS_UP | 81 | 18 | 17377 | 1707 |
ARHGAP26,RUNX2,IL32,IL15,SLC27A2,TGFA,ATF3,ADAMTS6,ID3,ASNS,CCBE1,LHX6,INPP4B,CYP2U1,MYO6,KLHL29,STON2,SNAI2 |
| 7.339e-04 | -7.22 | phosphatidylinositol binding | molecular function | GO:0035091 | 236 | 39 | 17224 | 1680 |
STXBP6,PLEKHA5,MYO1B,ITPR2,SNX9,PFN2,ZFYVE9,SCIN,GSDME,TECPR1,ZFYVE28,MCF2L,RUNDC3B,SGK3,DAB2IP,SH3PXD2B,CLVS2,DENND1C,SNX10,FES,SNX7,GAB2,MARK1,ARAP2,MYO10,PLEKHA8,PARD3B,CYTH3,FERMT2,HIP1,ARHGAP32,PLEKHA1,PLCB1,FCHO2,OSBPL5,LAPTM4B,PIK3C2B,PLD1,PXDC1 |
| 7.362e-04 | -7.21 | SAM_1 | pfam domains | PF00536 | 62 | 15 | 17054 | 1666 |
ARAP2,INPPL1,L3MBTL4,PPFIBP1,KAZN,CNKSR3,PPFIA2,SHANK2,PPFIBP2,PPFIA4,SFMBT1,SAMD13,EPHB1,MAP3K20,PHC1 |
| 7.366e-04 | -7.21 | collagen-activated tyrosine kinase receptor signaling pathway | biological process | GO:0038063 | 9 | 5 | 17256 | 1658 |
COL4A5,COL4A3,DDR1,SYK,UBASH3B |
| 7.366e-04 | -7.21 | negative regulation of membrane potential | biological process | GO:0045837 | 9 | 5 | 17256 | 1658 |
BNIP3,PMAIP1,PRELID1,BNIP3L,SLC25A27 |
| 7.378e-04 | -7.21 | positive regulation of mast cell degranulation | biological process | GO:0043306 | 13 | 6 | 17256 | 1658 |
FGR,GATA2,STXBP1,SYK,VAMP8,GAB2 |
| 7.378e-04 | -7.21 | amino acid import across plasma membrane | biological process | GO:0089718 | 13 | 6 | 17256 | 1658 |
SLC7A1,SLC36A4,SLC3A2,SLC7A2,SLC1A3,SLC1A5 |
| 7.378e-04 | -7.21 | positive regulation of mast cell activation involved in immune response | biological process | GO:0033008 | 13 | 6 | 17256 | 1658 |
FGR,GATA2,STXBP1,SYK,VAMP8,GAB2 |
| 7.378e-04 | -7.21 | regulation of natural killer cell differentiation | biological process | GO:0032823 | 13 | 6 | 17256 | 1658 |
STAT5B,TOX,PRDM1,GAS6,IL15,RASGRP1 |
| 7.378e-04 | -7.21 | bundle of His cell to Purkinje myocyte communication | biological process | GO:0086069 | 13 | 6 | 17256 | 1658 |
TRPM4,PKP2,SCN5A,DSP,DSG2,CACNA2D1 |
| 7.413e-04 | -7.21 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | 219 | 37 | 17377 | 1707 |
MAN2B2,ANO10,ENO2,ASS1,PKP2,PRKCA,ABHD6,PFN2,F3,GATA2,HPS1,BNIP3,KLF9,RAB27B,THSD1,ZNF385A,NOS3,DUSP1,PDLIM7,GCNT2,PDK1,TES,CAPN5,SPATA13,DEPTOR,DUSP9,LHPP,HOXA1,FAM162A,MAP1B,ISG20,BCL11A,P4HA2,MPP2,SEPT5,NPHP1,OSBPL6 |
| 7.427e-04 | -7.21 | AAAYRNCTG_UNKNOWN | MSigDB lists | AAAYRNCTG_UNKNOWN | 338 | 52 | 17377 | 1707 |
PCDH18,SCN5A,ACVR1,ID1,SCN8A,COL4A5,COLEC10,FOXG1,SNX9,DYNC1I1,PFN2,PPP2R3A,ARHGAP44,CCNJ,TRPS1,RTN1,FOXP2,RGS17,MGAT1,CACNB2,STC2,MPPED2,ZNF521,ERRFI1,VWA5A,GFI1,B4GALT6,PODXL2,PXN,KLHL3,SOX21,ESRRG,RAPGEF4,JPH1,FGF12,TNS1,PRKCQ,ROR1,ZFPM2,ASPH,FGFR1,ZIC1,INHBC,MAP2,NXPH4,KLF5,HGF,CDH2,MID1,FOXA1,RAB30,CNTN1 |
| 7.445e-04 | -7.20 | GO_LAMELLIPODIUM | MSigDB lists | GO_LAMELLIPODIUM | 166 | 30 | 17377 | 1707 |
WASF3,FER,INPPL1,AMOTL1,EVL,PXN,MYO10,PTPN13,APBB1,SPATA13,FERMT2,ENAH,PALLD,RAC3,PPP1R9A,CTNNA2,TIAM2,SLC39A14,GSN,ABLIM1,PLEKHH2,SH3RF1,FAT1,ABI3,ITGB3,MCC,ACTA2,CTTN,CDH2,TESC |
| 7.445e-04 | -7.20 | GO_RECEPTOR_SIGNALING_PROTEIN_ACTIVITY | MSigDB lists | GO_RECEPTOR_SIGNALING_PROTEIN_ACTIVITY | 166 | 30 | 17377 | 1707 |
TYRO3,PAK1,TNIK,ACVR1,SMAD9,BMPR2,ACVR1C,KCNH5,SLK,LRRK2,RYR2,RASA3,STRADB,CHUK,MAPK4,ACVR2B,ITPR2,DOK5,STK24,TIAM2,SMAD3,MAP2K6,FLRT3,ADRB1,ACVR2A,MAPK13,BMPR1A,MAPK10,SMAD6,SYK |
| 7.452e-04 | -7.20 | cellular response to oxygen-containing compound | biological process | GO:1901701 | 924 | 118 | 17256 | 1658 |
EPHA3,PRKN,SORBS1,ID1,IL15,LDLR,ASS1,LILRB1,NTRK3,CHUK,STAT5B,ITPR2,FBXO32,UNC13B,DAB2IP,PDE4D,TLR4,TSHR,SLIT2,PRKACB,CYP1B1,GDAP1,FER,SESN2,ATF4,FZD4,LRRK2,ADCY1,YAP1,PRKAR2B,WNT11,ABCC2,PLEKHA1,CD40,SESN1,SNCA,GNAI1,IRS2,ENPP1,CXCL10,INSIG1,PTK7,EIF4EBP1,GNB4,ERN1,ITGA2,RGS10,MAPK13,KLF5,TPM1,TNFSF4,PPARGC1A,RRAGD,MEF2C,PRKAA2,GNG12,PLSCR4,IPO5,ATP6V1E2,GAS6,MLC1,DDIT4,NKX6-1,RAB11FIP5,HMGCS1,IGF1R,CA2,PRKCD,GHR,SREBF1,LRP6,ADCY6,BNIP3,KLF9,ERRFI1,PCK2,ESD,GFI1,CHRM3,ATP2B1,NOS3,PAK1,TRPM4,RHOQ,PXN,MSTN,NR4A1,NUGGC,RAPGEF2,LITAF,CALCRL,RYR2,MARS,RACK1,TLR6,PLCB1,BAIAP2,CPEB1,GPLD1,CEBPB,TRIB3,ID3,FBN1,MAP2K6,XBP1,SH3BP4,RAB31,PCGF2,PTPRN2,CMPK2,CERS1,TBC1D4,TESC,SMYD3,CACNA2D1,ATP2B4,LARP1,ATP1A3 |
| 7.481e-04 | -7.20 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | 181 | 32 | 17377 | 1707 |
IL15,MCTP2,SPATS2L,SFXN3,SLCO3A1,HOPX,MCOLN2,TLR3,ZBTB38,TGFBR3,EOMES,JAKMIP2,TOX,TMED9,SP140,PPP2R2B,GFI1,MICAL2,PHLDB2,SH3BP2,SESN2,TTYH2,ZDHHC14,SMAD3,GALNT3,PTPRJ,ERN1,PAM,SERPINI1,ATP2B4,LPP,STOM |
| 7.481e-04 | -7.20 | GSE40273_XBP1_KO_VS_WT_TREG_UP | MSigDB lists | GSE40273_XBP1_KO_VS_WT_TREG_UP | 181 | 32 | 17377 | 1707 |
MXI1,PRSS12,LPCAT2,ELOVL7,BLVRB,APBB1,EPS8,TNFAIP8L2,ABHD13,SELL,SNX9,INPP1,CD53,FBXO32,CA2,SLC30A4,CNKSR3,TMEM86A,BCL6,FAM84B,ANTXR2,PNP,SPATA6,STAT4,WLS,LRMP,CYTH3,C1orf174,GABARAPL1,SLC7A5,SLC16A10,CSRP2 |
| 7.499e-04 | -7.20 | BHAT_ESR1_TARGETS_VIA_AKT1_UP | MSigDB lists | BHAT_ESR1_TARGETS_VIA_AKT1_UP | 266 | 43 | 17377 | 1707 |
UST,BCL11B,TBKBP1,RGS16,THOC5,FARP1,RNF144A,SYT12,BEGAIN,SLC7A2,OVOL2,TPD52L1,STK24,NCS1,CYP26A1,GPRIN1,CNKSR3,KAZN,STC2,REEP1,MPPED2,TMEM120B,GAB2,CYP1B1,SUSD3,SH2D2A,SYBU,FHL2,WWC1,ATF3,TBC1D16,HOMER3,TSKU,KCNK15,PDLIM3,WFS1,MFSD2A,XBP1,SLC7A5,HK2,SVIL,CERS1,PTGES |
| 7.499e-04 | -7.20 | STK33_UP | MSigDB lists | STK33_UP | 266 | 43 | 17377 | 1707 |
ACVR1,DUSP8,GPR65,SETBP1,HECW2,C20orf194,FAM198B,CREB5,SLC12A6,TTC30B,RTN1,RNF141,OTUD1,SIPA1L2,KIAA0895,PRTFDC1,SLC7A11,KMO,GAN,BCL6,SGK1,MORN2,NCEH1,VWA5A,DUSP1,RIN2,ARID5B,MAFB,FNDC3A,TTLL7,ASPH,GPR137C,TLR6,GLCE,FCHO2,TDO2,RND3,WDR19,DYNC2LI1,TNFSF15,NRP1,FNBP1L,ACSM3 |
| 7.512e-04 | -7.19 | voltage-gated potassium channel complex | cellular component | GO:0008076 | 91 | 19 | 18223 | 1724 |
DPP10,KCNV1,KCNIP3,KCNQ3,AMIGO1,KCND3,SNAP25,KCNC4,NOS1AP,KCNJ4,LRRC55,KCNMB4,KCNAB1,KCNG1,KCNS3,KCNMB3,DLG2,CTTN,KCNB2 |
| 7.566e-04 | -7.19 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | 479 | 69 | 17377 | 1707 |
ZNF516,UGDH,GATA3,FAM102B,SLC7A2,ABAT,NHP2,AARS,SEMA6A,HMCN1,KCTD15,ASNS,ATRNL1,SNX10,DOCK8,SNAI2,EVL,NECAB1,THSD4,CAP2,ADCY1,FEZ1,BATF,RNF44,DSP,ZNF711,SLC7A1,ITGA2,INPP4B,AHNAK2,BDH2,BCL11B,ZCCHC24,JDP2,IPO5,C1orf226,ARL2,ZIC2,COL4A5,SFXN3,TPD52L1,PPP2R3A,CA2,RALGPS2,IGF1R,MYC,STC2,SGK3,IQGAP3,TBC1D9,PCK2,FAM155A,ESD,GFRA1,RPS23,RIMS2,SYNPO2,SYBU,KIAA1324L,PALLD,PLCB1,DKK1,HOMER3,MAPKAPK2,RAB31,SVIL,RPS12,SMYD3,OSBPL6 |
| 7.574e-04 | -7.19 | GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_CONTRACTION | MSigDB lists | GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_CONTRACTION | 27 | 9 | 17377 | 1707 |
TRPM4,SCN5A,ANK2,DSG2,RYR2,PKP2,PDE4D,DSP,NOS1AP |
| 7.574e-04 | -7.19 | PLASARI_NFIC_TARGETS_BASAL_UP | MSigDB lists | PLASARI_NFIC_TARGETS_BASAL_UP | 27 | 9 | 17377 | 1707 |
NRN1,TEX15,KCNMB4,SEMA4F,THSD4,FOXA1,PERP,SNCA,MPPED2 |
| 7.574e-04 | -7.19 | WOTTON_RUNX_TARGETS_DN | MSigDB lists | WOTTON_RUNX_TARGETS_DN | 27 | 9 | 17377 | 1707 |
ID3,CDH26,SIPA1L2,ENO2,PLOD2,RNF144A,FNDC3A,ERRFI1,CEBPD |
| 7.574e-04 | -7.19 | GO_CARDIAC_MUSCLE_CELL_CONTRACTION | MSigDB lists | GO_CARDIAC_MUSCLE_CELL_CONTRACTION | 27 | 9 | 17377 | 1707 |
SCN5A,SCN1B,CACNB2,ANK2,FGF12,RYR2,PKP2,CACNA2D1,GJC1 |
| 7.638e-04 | -7.18 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902235 | 33 | 10 | 17256 | 1658 |
PRKN,ATF4,PMAIP1,WFS1,LRRK2,MAGEA3,XBP1,ATF3,HERPUD1,DDIT3 |
| 7.665e-04 | -7.17 | EGF_Ca-bd_CS | interpro domains | IPR018097 | 95 | 20 | 18492 | 1811 |
LRP4,VLDLR,LDLR,C1R,GAS6,DNER,HMCN1,HEG1,EFEMP1,NELL2,FAT4,FBN1,FAT1,CCBE1,THBS4,BMP1,EGFL7,PROS1,SLIT2,TLL2 |
| 7.726e-04 | -7.17 | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | MSigDB lists | HERNANDEZ_ABERRANT_MITOSIS_BY_DOCETACEL_4NM_UP | 22 | 8 | 17377 | 1707 |
SGK1,MAGEA12,PRAME,HLF,GEM,RASGRP1,GHR,CD53 |
| 7.736e-04 | -7.16 | V$PAX_Q6 | MSigDB lists | V$PAX_Q6 | 235 | 39 | 17377 | 1707 |
PHACTR3,AMOTL1,BLVRB,UBAC2,GATA3,FAM81A,TNKS1BP1,NOVA1,SLCO3A1,PRRG4,NEDD4,TMEM53,CHN2,CHRDL1,LMAN2,SPRY2,PTCH2,BDNF,MEIS2,HNF4G,PTPN6,SLITRK5,ATF3,PRDM1,FBXO36,BATF,BATF3,EBF1,MYADM,MAP2K6,P4HA2,GNB4,PTK7,DLG2,LRRK1,SEMA3A,NKX2-8,HOXB9,FOXA1 |
| 7.768e-04 | -7.16 | regulation of axonogenesis | biological process | GO:0050770 | 170 | 30 | 17256 | 1658 |
UST,PAK1,SSH3,BDNF,ZSWIM5,FN1,ROBO2,BMPR2,FGF13,DCC,LRP4,PLXNA2,NTRK3,AMIGO1,MAP1B,NKX6-1,CHN1,RND2,SEMA4F,MAP2,PTPRS,SEMA3C,CTTN,SPART,NRP1,SHOX2,SEMA3A,CDH2,SLIT2,SHTN1 |
| 7.804e-04 | -7.16 | BRUNO_HEMATOPOIESIS | MSigDB lists | BRUNO_HEMATOPOIESIS | 62 | 15 | 17377 | 1707 |
AK1,CD55,MSMO1,ST6GAL1,CAPN5,HK2,ENAH,BNIP3,TJP1,SCD,CPE,SESN1,DHCR7,CD53,HMGCR |
| 7.804e-04 | -7.16 | BASSO_CD40_SIGNALING_DN | MSigDB lists | BASSO_CD40_SIGNALING_DN | 62 | 15 | 17377 | 1707 |
VNN2,ID3,ITGB7,ID1,IGFBP6,RAPGEF2,ST6GAL1,BIK,CDH17,BCL6,PRKAR2B,SYK,RAPGEF5,RERE,ISG20 |
| 7.813e-04 | -7.15 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_UP | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_UP | 189 | 33 | 17377 | 1707 |
PLA2G4A,LRP4,APBB1,TUBE1,CHADL,CHSY1,HERC6,PHGDH,DDR1,HOPX,MCOLN2,FOXP2,GPRIN1,AFF2,RAP2A,MED7,RRAS2,SLIT2,FES,MED12L,RBMS2,PARP9,DLGAP1,MPP1,TSKU,ARHGAP21,TMEM154,MATN2,ABI3,SLC7A5,TNFRSF1A,GRIN2D,SLFN5 |
| 7.813e-04 | -7.15 | GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | MSigDB lists | GSE1925_CTRL_VS_3H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | 189 | 33 | 17377 | 1707 |
TYRO3,BTC,INPPL1,ENO2,WLS,ITGA6,CAPN5,HOMER2,FGF12,RYR2,CHRNA6,TGDS,TLR6,MGMT,FHOD3,CEBPB,MCOLN2,BEX4,CACHD1,CDR2L,CA2,DSG2,LAPTM4B,DAB2IP,ZBTB20,SERPINI1,CTTN,PROS1,PPARGC1A,MAPK10,MED12L,PKIA,PHC1 |
| 7.813e-04 | -7.15 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | MSigDB lists | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 | 189 | 33 | 17377 | 1707 |
INPPL1,TRIM2,AASS,SEC24D,REL,ATP8A1,FAM13A,PPP2R3A,HOPX,CDS1,PLS3,EFEMP1,RPS6KA2,UNC13B,PRKCD,KCNS3,SCRN1,LIMCH1,CEBPD,NOS3,DUSP1,NKX2-1,CD55,RAPGEF2,SLC39A8,SMARCD3,CDC42BPA,ATP11A,RAB38,AK1,MAOA,GEM,ATP2B4 |
| 7.813e-04 | -7.15 | GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP | 189 | 33 | 17377 | 1707 |
RGS16,ACSL1,REL,ATP8A1,PGAP1,PLS3,CYP51A1,CA2,BCL6,TSC22D1,EPHB6,SYNGR3,GATM,BCL7A,GAPDH,SLC27A2,DNAJC6,NFIA,LITAF,ATF3,PDE8A,GSTO1,ATP1B1,MBNL2,PLCB1,ID3,ZNF266,PLAGL1,RGS10,LAPTM4B,INPP5F,GEM,TLL2 |
| 7.813e-04 | -7.15 | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_UP | 189 | 33 | 17377 | 1707 |
CREB3L2,SERINC5,SEMA6B,RHOD,LRP4,SCD,GPSM2,UNC13B,SLC7A11,SMTN,GSTM3,PCOLCE2,IGSF3,GLDC,HRASLS,TUBA1A,GSTM4,TGFA,CAP2,MGST3,MGAT4B,EFHC1,COTL1,PALLD,UCHL3,BAIAP2,NT5DC2,EML1,DEXI,TMCO3,C1orf21,AHNAK2,SVIL |
| 7.826e-04 | -7.15 | GO_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | MSigDB lists | GO_SUBSTRATE_ADHESION_DEPENDENT_CELL_SPREADING | 38 | 11 | 17377 | 1707 |
TYRO3,FER,ITGB7,FN1,FZD4,BVES,ITGB3,LAMB1,FERMT2,RADIL,PEAK1 |
| 7.826e-04 | -7.15 | PID_RAC1_REG_PATHWAY | MSigDB lists | PID_RAC1_REG_PATHWAY | 38 | 11 | 17377 | 1707 |
CHN1,VAV3,CHN2,DOCK1,RASGRF2,EPS8,PREX1,SPATA13,DOCK2,DOCK6,TIAM2 |
| 7.830e-04 | -7.15 | response to drug | biological process | GO:0042493 | 898 | 115 | 17256 | 1658 |
PRKN,ID1,ACSL1,PDE1B,ASS1,GATA3,COL18A1,NTRK3,CHUK,ITPR2,SLC7A2,ABAT,SLC19A2,STK24,PPM1E,FBXO32,TLR3,ASNS,CHRNA5,SLC22A18,RAP2A,SLIT2,PRKACB,PDGFRB,CYP1B1,FZD1,TRDMT1,ATF4,FZD4,LRRK2,ADCY1,YAP1,CHRNA6,PRKAR2B,ABCC2,PLEKHA1,CD40,SNCA,GNAI1,SLC7A1,GSN,NCKAP1L,EIF4EBP1,PEMT,ASIC1,ITGA2,RGS10,PAM,HPGD,SEMA3C,MAPK13,CYP2U1,OXTR,ATG5,PPARGC1A,MEF2C,PRKAA2,SLC6A9,CYP2J2,SELL,HBE1,SLC36A4,GAS6,SLC1A3,ADSSL1,DDIT4,NKX6-1,HMGCS1,EEF2,SLC7A11,CA2,ZNF354A,BCHE,MYC,DSG2,PRKCD,SREBF1,INAVA,ADCY6,BNIP3,IPCEF1,KLF9,ERRFI1,MYO6,PCK2,CHRM3,DUSP1,HMGCR,VEGFC,TRPM4,HBG2,VAV3,MSX1,GSTM2,PNP,MSTN,SLC36A1,HOMER2,AK4,RYR2,SDK1,PLCB1,MGMT,BAIAP2,GPLD1,ACER2,GNAO1,MAP2K6,PCGF2,SLC1A5,CERS1,TRPC3,KIF1B,SMYD3,LARP1 |
| 7.831e-04 | -7.15 | cholesterol metabolic process | biological process | GO:0008203 | 111 | 22 | 17256 | 1658 |
PRKAA2,MVK,MVD,LDLR,VLDLR,DHCR24,NFE2L1,CEBPA,NPC2,LEPR,CYP51A1,IDI1,HMGCS1,INSIG1,SOAT2,MSMO1,OSBPL5,SREBF1,SQLE,DHCR7,ABCG1,HMGCR |
| 7.847e-04 | -7.15 | signaling adaptor activity | molecular function | GO:0035591 | 82 | 18 | 17224 | 1680 |
VAV3,SH3BP2,SORBS1,SKAP2,GRB14,SH2D2A,EPS8,RACK1,SKAP1,CHN1,CHN2,MPP7,DUSP19,SHF,GRB10,AFAP1L2,DAB2IP,GAB2 |
| 7.847e-04 | -7.15 | calmodulin binding | molecular function | GO:0005516 | 198 | 34 | 17224 | 1680 |
MYO1D,SCN5A,RGS16,PDE1B,AKAP5,MYO1B,ADD2,TJP1,KCNN2,UNC13B,MYH15,MARCKS,IQGAP3,FBXL2,MYO6,ATP2B1,CTH,NOS3,TRPM4,ATP5IF1,KCNQ3,MYO10,KCNH5,ADCY1,OBSCN,RYR2,SNTB1,PLCB1,MAPKAPK2,MAP2,WFS1,RASGRF2,GEM,ATP2B4 |
| 7.851e-04 | -7.15 | post-embryonic development | biological process | GO:0009791 | 90 | 19 | 17256 | 1658 |
BCL11B,INPPL1,KDM5B,ARID5B,ACO1,GATA3,GABRG2,PRDM1,ACVR2B,PYGO1,PLEKHA1,SELENOP,HEG1,FOXP2,EFEMP1,FBN1,SEMA3C,BMP4,DHCR7 |
| 7.851e-04 | -7.15 | endothelium development | biological process | GO:0003158 | 90 | 19 | 17256 | 1658 |
SLC40A1,ID1,ACVR1,BMPR2,RAPGEF2,COL18A1,TJP1,ACVR2B,ARHGEF26,HEG1,MYADM,MARVELD2,PTPRS,GSTM3,BMP4,PDE4D,MET,NRP1,HEY1 |
| 7.861e-04 | -7.15 | YTAATTAA_V$LHX3_01 | MSigDB lists | YTAATTAA_V$LHX3_01 | 174 | 31 | 17377 | 1707 |
RAX,LRFN5,INPPL1,JDP2,VAMP8,PACSIN3,PRDM8,PRDM1,NOVA1,SP8,ARHGAP44,MAP1B,NEO1,NKX6-1,ARHGEF10L,ATXN7L1,PPM1E,KCTD15,BACE2,GNAO1,TFAP2A,ZBTB20,HRK,SH3BGRL2,MARCKS,FIGN,SMAD6,SHOX2,SEMA3A,MYT1,MID1 |
| 7.862e-04 | -7.15 | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | MSigDB lists | KAAB_HEART_ATRIUM_VS_VENTRICLE_UP | 243 | 40 | 17377 | 1707 |
CREB3L2,ENO2,IGFBP6,CFH,EPS8,XYLT1,STAT5B,INPP1,DDR1,GAS1,EFEMP1,EPB41L3,TGFBR3,KAZN,SLC22A18,PRKCD,CHRDL1,ACTA2,TRPC1,FAM155B,ZNF365,CPE,ZFP36L2,NEB,MICAL2,QSOX1,TNK2,SLC39A8,STAT4,FEZ1,C1R,VIM,RARRES2,RABAC1,PLCB1,MAP1B,HEG1,GNAO1,PAM,UNC5B |
| 7.885e-04 | -7.15 | V$CHX10_01 | MSigDB lists | V$CHX10_01 | 212 | 36 | 17377 | 1707 |
CGN,PCDH18,LRFN5,VAMP8,PLXNA2,NEO1,MTUS1,RPL34,TUBB4A,FOXP2,ATXN7L1,PPM1E,CA2,GRHL1,BACE2,FLRT3,BCL6,FIGN,ETV1,SEMA6C,NKX2-1,NDUFA4L2,MSX1,MSTN,NR6A1,VLDLR,ZIC1,ADAMTS17,GNAO1,BMP1,MAOA,DLG2,BMP4,SHOX2,FILIP1,ATP2B4 |
| 7.895e-04 | -7.14 | Golgi subcompartment | cellular component | GO:0098791 | 820 | 105 | 18223 | 1724 |
PCSK1N,SCAMP1,LPCAT2,GALNT12,GALNT6,ATP8A1,XYLT1,MYO1B,RGS20,RNF24,CHAC1,FAM198B,MGAT5B,SNX9,CHST10,SLC9A7,TLR3,SEC16B,RAB26,NBEA,TMED9,PROS1,COG3,CLVS2,RAB27B,GALNT18,RASGRP1,ATL1,CD55,GCNT2,ERGIC1,B3GALT1,WLS,TGFA,LRRK2,RNF125,CBY1,PXYLP1,RAB38,ARHGAP21,GBP1,ATP7B,TNFRSF1A,B3GALT2,PAM,DSEL,HS3ST3B1,RAB30,HACE1,UST,HID1,SEC24D,BACE1,ATP9A,ST6GAL1,DHCR24,CLSTN2,GALNT13,CHSY1,NDFIP2,GSAP,RAB11FIP5,GALNT1,GBGT1,ABCA5,MGAT1,FUT9,SREBF1,HS3ST5,LMAN2,FIG4,ST8SIA1,NCAM1,B4GALT6,NOS3,CHSY3,IL17RD,QSOX1,PLEKHA8,RAB6B,CYTH3,SYBU,MGAT4B,LITAF,GPSM1,ST6GALNAC3,GALNT17,ARHGAP32,SNAP25,FNDC3A,B4GALNT3,GALNT14,GLCE,GALNT3,ICA1,SH3GL2,RND3,PMEPA1,ACER2,QPCTL,RAB31,PLD1,CERS1,B4GALT7,ABCG1 |
| 7.908e-04 | -7.14 | ruffle | cellular component | GO:0001726 | 165 | 29 | 18223 | 1724 |
EPB41L5,PAK1,PDLIM7,MYO10,CYTH3,EPS8,SPATA13,ASAP3,PSD3,WWC1,PLEKHA1,PALLD,SNX9,BAIAP2,ARHGEF26,GSN,FGR,PTPRJ,MYADM,ITGB3,CTTN,SPRY4,TPM1,TLN2,MYO6,PACSIN1,COBL,TESC,SPRY2 |
| 7.917e-04 | -7.14 | dendrite morphogenesis | biological process | GO:0048813 | 57 | 14 | 17256 | 1658 |
FARP1,MAP2,RBFOX2,LRP4,SHANK2,VLDLR,SLITRK5,NRP1,EPHB1,ZNF365,SEMA3A,CTNNA2,CTNND2,RERE |
| 7.957e-04 | -7.14 | Activin_recp | pfam domains | PF01064 | 9 | 5 | 17054 | 1666 |
ACVR2A,BMPR1A,ACVR2B,ACVR1,BMPR2 |
| 8.002e-04 | -7.13 | Rho GTPase cycle | REACTOME pathways | R-HSA-194840 | 143 | 26 | 10287 | 971 |
ARHGAP26,VAV3,ARAP2,RHOQ,ARHGEF11,RHOBTB1,RHOD,ARHGAP22,PREX1,OPHN1,OBSCN,ARHGAP32,FAM13A,RAC3,TIAM2,ARHGAP44,ARHGEF26,SYDE2,ARHGEF10L,CHN1,ARHGAP21,CHN2,MCF2L,RASGRF2,SRGAP1,ARHGAP28 |
| 8.015e-04 | -7.13 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 | 75 | 17 | 17377 | 1707 |
FADS1,DBN1,PDLIM7,COL6A2,GAPDH,COL18A1,FEZ1,NPDC1,PFN2,PCDH7,TUBB4A,CYP51A1,IDI1,FBN1,MSMO1,MAOA,SQLE |
| 8.015e-04 | -7.13 | RNCTGNYNRNCTGNY_UNKNOWN | MSigDB lists | RNCTGNYNRNCTGNY_UNKNOWN | 75 | 17 | 17377 | 1707 |
BCL11B,TYRO3,ID1,C4A,ANK2,ELMOD1,MBNL2,BMP6,ATXN7L1,BMP1,ACVR2A,NBEA,TUFT1,HOXB9,MID1,NOS3,NKX2-1 |
| 8.042e-04 | -7.13 | protein tyrosine kinase activity | molecular function | GO:0004713 | 183 | 32 | 17224 | 1680 |
EPHA3,FGFR4,TYRO3,FER,TNK2,BTC,DYRK3,CRIM1,EFNA3,NTRK3,STAT5B,ROR1,FGF17,EPHB1,PEAK1,DDR1,FRK,FGFR1,DYRK1B,EFEMP1,FGR,IGF1R,MAP2K6,PRKCD,MAP3K21,HGF,EPHB6,MET,NRP1,SYK,PDGFRB,FES |
| 8.053e-04 | -7.12 | Activin_recp | interpro domains | IPR000472 | 9 | 5 | 18492 | 1811 |
ACVR2A,BMPR1A,ACVR2B,ACVR1,BMPR2 |
| 8.071e-04 | -7.12 | WW_DOMAIN_1 | prosite domains | PS01159 | 41 | 12 | 12060 | 1278 |
BAG3,PLEKHA5,APBB1,WWTR1,YAP1,WWC1,HECW2,TCERG1L,WWC2,MAGI2,NEDD4,MAGI3 |
| 8.080e-04 | -7.12 | GO_RUFFLE | MSigDB lists | GO_RUFFLE | 152 | 28 | 17377 | 1707 |
EPB41L5,PAK1,PDLIM7,MYO10,CYTH3,EPS8,ASAP3,SPATA13,WWC1,PLEKHA1,PALLD,SNX9,ARHGEF26,BAIAP2,GSN,FGR,PTPRJ,MYADM,ITGB3,CTTN,SPRY4,PACSIN1,TLN2,MYO6,TPM1,SPRY2,TESC,COBL |
| 8.080e-04 | -7.12 | GSE11386_NAIVE_VS_MEMORY_BCELL_DN | MSigDB lists | GSE11386_NAIVE_VS_MEMORY_BCELL_DN | 152 | 28 | 17377 | 1707 |
MYCBP2,EVL,SIDT1,KDM5B,REL,ATP8A1,PTPN13,RIMKLA,PANK1,RAPGEF4,CR2,PLEKHA1,PRKCA,MBNL2,DOCK2,ATP10D,BEX2,DDIT4,NAP1L5,EPCAM,NSD1,ID3,BACH2,KCNAB1,PLOD2,TSPAN13,TOX,AGL |
| 8.096e-04 | -7.12 | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | MSigDB lists | COULOUARN_TEMPORAL_TGFB1_SIGNATURE_UP | 102 | 21 | 17377 | 1707 |
PDLIM7,SLC40A1,ERGIC1,TBC1D1,ITGA6,VIM,SPATS2L,DDR1,NCS1,DDIT4,DHX32,CXCL10,IDI1,ASNS,FCHO2,PMEPA1,SQLE,SGK1,NRP1,UNC5B,CHMP4C |
| 8.096e-04 | -7.12 | GO_CARDIAC_CHAMBER_MORPHOGENESIS | MSigDB lists | GO_CARDIAC_CHAMBER_MORPHOGENESIS | 102 | 21 | 17377 | 1707 |
ACVR1,FHL2,GATA3,PKP2,SMARCD3,RYR2,WNT11,OVOL2,ZFPM2,SAV1,DSP,HEG1,TGFBR3,HEYL,SEMA3C,TPM1,CPE,SHOX2,HEY1,FZD1,MEF2C |
| 8.109e-04 | -7.12 | STK33_NOMO_UP | MSigDB lists | STK33_NOMO_UP | 267 | 43 | 17377 | 1707 |
EFNB2,ACVR1,SETBP1,HECW2,C20orf194,PSD3,ZIC2,FAM198B,SLC12A6,LACC1,FAM13A,TTC30B,HECTD2,SIPA1L2,OTUD1,FBXO32,EOMES,KMO,GAN,BCL6,SGK1,JAKMIP2,MORN2,NCEH1,VWA5A,PGBD5,DUSP1,RIN2,GCNT2,ARID5B,MGAT4B,CTTNBP2NL,FNDC3A,ASPH,TLR6,FCHO2,TDO2,RND3,WDR19,TNFSF15,CAB39L,NRP1,ACSM3 |
| 8.130e-04 | -7.11 | AGGAAGC,MIR-516-3P | MSigDB lists | AGGAAGC,MIR-516-3P | 116 | 23 | 17377 | 1707 |
BCL11B,ANTXR2,RAB6B,STAT4,BNIP3L,COL18A1,SATB2,CREB5,SDK1,HERC6,PLCB1,BAIAP2,MTUS1,FAM131B,SLC7A1,TMEM154,MAP9,XBP1,MYO3B,PIK3C2B,NCAM1,RIMS2,B4GALT7 |
| 8.167e-04 | -7.11 | regulation of stress-activated MAPK cascade | biological process | GO:0032872 | 217 | 36 | 17256 | 1658 |
PRKN,TNIK,EDA2R,GRIK2,FZD8,PKN1,EPHB1,TPD52L1,TNFRSF19,MECOM,TGFBR3,TLR3,IGF1R,DACT1,MYC,RAP2A,INAVA,DAB2IP,TNFRSF11A,SYK,RASGRP1,HMGCR,PAK1,FZD4,TLR6,PLCB1,MAGI3,DKK1,SH3RF1,ERN1,DUSP19,MAP3K21,HGF,SEMA3A,MAP3K20,MID1 |
| 8.204e-04 | -7.11 | COL8A2 (collagen type VIII alpha 2 chain) | protein interactions | 1296 | 17 | 7 | 17029 | 1718 |
COLGALT2,COL18A1,COL4A5,FN1,COL14A1,FKBP14,P4HA2 |
| 8.240e-04 | -7.10 | AAAGACA,MIR-511 | MSigDB lists | AAAGACA,MIR-511 | 182 | 32 | 17377 | 1707 |
THOC5,TRIM2,FN1,ROBO2,FGF13,RECK,ZCCHC24,LMCD1,EYA4,SLC22A17,RPS6KL1,KLF9,VAV3,PCDH10,CRIM1,MSTN,FOXN3,ESRRG,EDEM3,SATB2,KHDRBS2,BCL11A,CAMK2N1,DYRK1B,ENPP1,HLF,PMEPA1,EMILIN2,C1orf21,PPARGC1A,CDH2,LPP |
| 8.240e-04 | -7.10 | GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_DN | MSigDB lists | GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_DN | 182 | 32 | 17377 | 1707 |
MOCOS,AMOTL1,LGALS3,RHOD,TDRKH,GRK6,FAM81A,ZNF219,CD7,CACNB4,IL18R1,PRICKLE2,FIGN,SMAD6,DLGAP1,KLHL4,NR4A1,LRMP,CHRNA6,HIP1,MEI1,COTL1,C1orf174,TBC1D2,ICA1,SH3RF1,ZNF697,NCAM2,PLXDC2,EIF4EBP1,FAM149A,DISP1 |
| 8.240e-04 | -7.10 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_DN | 182 | 32 | 17377 | 1707 |
TNIK,SLC6A9,SH2D2A,MYO10,PSTPIP2,SLC39A8,MCTP2,ACO1,CALCRL,PFN2,TBC1D30,STEAP1,NT5DC2,DDIT4,DEXI,EPB41L3,HPSE,MYC,P4HA1,MAOA,LAPTM4B,STEAP3,TSPAN13,MET,PRR16,PTGES,CKAP4,SLC16A10,SMPDL3A,SIX2,LAMP3,TLL2 |
| 8.240e-04 | -7.10 | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_DN | MSigDB lists | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_DN | 182 | 32 | 17377 | 1707 |
UST,EXPH5,MTG1,ITGA6,RASL11B,CUEDC2,GABRR2,SFXN3,SEZ6L2,TXNRD3,CA2,LRRC6,TACC2,CNKSR3,ADCY6,RASGRP1,ZNF629,ALDH2,LCA5,MGST3,RAPGEF4,ZDHHC15,RASA3,PRRG1,TBC1D16,HOXA1,DCBLD2,TRIB3,PEMT,RCN3,FNBP1L,PANK3 |
| 8.241e-04 | -7.10 | YAMAZAKI_TCEB3_TARGETS_UP | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_UP | 167 | 30 | 17377 | 1707 |
TYRO3,PDE1B,NR4A1,VAMP8,YPEL2,COBLL1,COL4A5,ATP1B1,FNDC3A,MBNL2,SEMA6A,CYP26A1,HERPUD1,FHOD3,WARS,F3,SLC7A1,FKBP9,EPB41L3,DDAH1,PLOD2,P4HA2,FLRT3,LAMB1,GHR,P4HA1,SERPINH1,PSPH,DOCK9,LPP |
| 8.259e-04 | -7.10 | GO_ENDOTHELIAL_CELL_DEVELOPMENT | MSigDB lists | GO_ENDOTHELIAL_CELL_DEVELOPMENT | 44 | 12 | 17377 | 1707 |
ID1,MYADM,MARVELD2,RAPGEF2,GSTM3,PTPRS,COL18A1,TJP1,PDE4D,MET,ARHGEF26,HEG1 |
| 8.259e-04 | -7.10 | NABA_COLLAGENS | MSigDB lists | NABA_COLLAGENS | 44 | 12 | 17377 | 1707 |
COL22A1,COL9A3,COL6A2,COL4A3,COL25A1,COL4A4,COL18A1,COL19A1,COL4A5,COL14A1,COL9A2,COL27A1 |
| 8.273e-04 | -7.10 | appendage morphogenesis | biological process | GO:0035107 | 148 | 27 | 17256 | 1658 |
B9D1,INTU,MSX1,RUNX2,RECK,LRP4,PLXNA2,ZNF219,ASPH,SP8,FGFR1,DKK1,SKI,DLX6,FRAS1,WDR19,TBC1D32,TFAP2A,LRP6,SEMA3C,HOXD13,DYNC2H1,BMPR1A,BMP4,SHOX2,MAP3K20,PCSK5 |
| 8.273e-04 | -7.10 | limb morphogenesis | biological process | GO:0035108 | 148 | 27 | 17256 | 1658 |
B9D1,INTU,MSX1,RUNX2,RECK,LRP4,PLXNA2,ZNF219,ASPH,SP8,FGFR1,DKK1,SKI,DLX6,FRAS1,WDR19,TBC1D32,TFAP2A,LRP6,SEMA3C,HOXD13,DYNC2H1,BMPR1A,BMP4,SHOX2,MAP3K20,PCSK5 |
| 8.295e-04 | -7.09 | regulation of ossification | biological process | GO:0030278 | 186 | 32 | 17256 | 1658 |
ID1,RUNX2,ACVR1,BMPR2,ZHX3,LRP4,CEBPA,CHSY1,KREMEN1,BMP6,SKI,TFAP2A,LRP6,ACVR2A,SMAD6,SNAI2,GLI1,INTU,TRPM4,PDLIM7,ACVR2B,DKK1,SMAD3,CEBPB,ENPP1,ID3,CSF1,HGF,BMP4,BMPR1A,SIX2,MEF2C |
| 8.295e-04 | -7.09 | peptidyl-tyrosine phosphorylation | biological process | GO:0018108 | 186 | 32 | 17256 | 1658 |
EPHA3,TYRO3,FGFR4,FER,TNK2,BTC,DYRK3,IL15,PTPN6,STAT5B,NTRK3,ROR1,FGF17,EPHB1,PEAK1,PIBF1,FRK,DDR1,FGFR1,EFEMP1,DYRK1B,FGR,IGF1R,MAP2K6,PRKCD,GHR,ABI3,HGF,MET,SYK,FES,PDGFRB |
| 8.312e-04 | -7.09 | WACKER_HYPOXIA_TARGETS_OF_VHL | MSigDB lists | WACKER_HYPOXIA_TARGETS_OF_VHL | 13 | 6 | 17377 | 1707 |
P4HA1,PDK1,ENO2,TGFA,HK2,IGFBP3 |
| 8.372e-04 | -7.09 | cellular response to organic cyclic compound | biological process | GO:0071407 | 500 | 70 | 17256 | 1658 |
PRKN,ID1,IL15,RBFOX2,ASS1,NPM1,CEBPA,ITPR2,PLPP1,FBXO32,TLR3,PDE4D,CYP1B1,GDAP1,ATF4,SMAD9,NR6A1,LRRK2,ADCY1,YAP1,AGO4,ABCC2,GNAI1,SNCA,SMAD3,INSIG1,EIF4EBP1,ITGA2,KLF5,PPARGC1A,NR3C2,HEY1,MEF2C,GABRB2,ITGA6,GABRG2,P2RY1,MLC1,NEDD4,DDIT4,HMGCS1,ADCY6,GRIP1,LRP6,KLF9,ERRFI1,PCK2,ZFP36L2,ATP2B1,TRPM4,GSTM2,MSTN,HNF4G,NR4A1,ESRRG,RAPGEF2,FHL2,RYR2,MGMT,GPLD1,CEBPB,ID3,TERT,PMEPA1,BMP4,SMYD3,LARP1,ATP2B4,BTRC,ATP1A3 |
| 8.387e-04 | -7.08 | tissue morphogenesis | biological process | GO:0048729 | 526 | 73 | 17256 | 1658 |
ACVR1,LGR4,ST14,GATA3,PKP2,DDR1,SKI,TGFBR3,SETDB2,EOMES,ITGB3,RAP2A,MET,SLIT2,PRKACB,SNAI2,NKX2-1,FZD1,INTU,KLHL3,WLS,YAP1,WNT11,DSP,FGFR1,SMAD3,PTK7,APELA,ITGA2,SEMA3C,BMPR1A,TMEFF2,NRP1,TPM1,COBL,HEY1,MEF2C,CELSR1,BMPR2,OPHN1,OVOL2,CA2,MYC,FRAS1,FLRT3,TFAP2A,LRP6,ACTA2,SPRY2,EPB41L5,PAK1,VEGFC,MICAL2,MSX1,KDM5B,DCHS1,PRICKLE1,RYR2,ZFPM2,HEG1,DKK1,FAT4,HEYL,CSF1,CTSV,MYOM2,HOXD13,BMP4,SHOX2,SEMA3A,SIX2,BTRC,FOXA1 |
| 8.405e-04 | -7.08 | PIK3R1 (phosphoinositide-3-kinase regulatory subunit 1) | protein interactions | 5295 | 230 | 39 | 17029 | 1718 |
TYRO3,EFNB2,WASF3,INPPL1,NPM1,LCP2,CD7,TLR3,IGF1R,PIK3AP1,RASD2,GHR,DAB2IP,PDE4D,FBXL2,MET,RRAS2,TSHR,SYK,IL1RAP,PDGFRB,FES,GAB2,VAV3,FER,PXN,SH2D2A,PTPN6,AGAP2,ARHGAP32,CD40,HOXA1,FGFR1,IRS2,TNFRSF1A,GRB10,DLX2,CDH2,MME |
| 8.432e-04 | -7.08 | acral | COSMIC cancer mutations | acral | 269 | 43 | 17385 | 1698 |
DOC2A,PCDH18,CACNG3,ARHGEF11,LRP4,ARHGAP22,SETBP1,HBE1,COL4A5,SLC12A6,COL14A1,BBS9,BMP6,FOXP2,SLC30A4,EHD3,COL19A1,SLC16A9,LIMCH1,TLN2,TLR4,KCNB2,SCN3A,GDAP1,ABCC4,DCC,SPOCD1,CRIM1,OGDHL,ACO1,YAP1,KCND3,CD40,PTPRC,ZNF711,TCF7L1,FAT4,TERT,ITGBL1,CDH17,UNC5B,NPHP1,MAST1 |
| 8.444e-04 | -7.08 | sodium channel complex | cellular component | GO:0034706 | 23 | 8 | 18223 | 1724 |
TRPM4,GRIK4,SCN5A,GRIK2,SCN1B,SCN8A,SCN2A,SCN3A |
| 8.448e-04 | -7.08 | skin-head_neck-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-head_neck-malignant_melanoma-superficial_spreading | 939 | 121 | 17385 | 1698 |
EXPH5,PLA2G4A,EPHA3,SORBS1,GRIK2,CELSR3,ATP8A1,GALNT6,MORC4,STAT5B,NTRK3,ADAMTS6,SYT14,KIF21B,KIAA1217,SNX9,NOVA1,COL22A1,TLR3,SLC10A7,COL19A1,PPP2R2B,CTTN,SCN2A,DNAH5,TLR4,NTNG1,SLIT2,HSPA2,RWDD2A,GDAP1,ABCC4,DCC,SPOCD1,PTPRU,TGFA,SHANK2,LRRK2,ADCY1,NLGN4X,SGK2,DSP,DOCK5,MAGI3,BATF3,ARMC4,CCBE1,RASGRF2,TMPRSS9,TECPR2,LAMB1,PTPRS,MAOA,RCN3,LIFR,CTNND2,MAST1,MAN2B2,PCDH18,DYRK3,ANKRD13B,PRSS16,CELSR1,REL,MCTP2,CLSTN2,GTF2IRD1,SETBP1,LAMC3,HBE1,GDPD5,SATB1,PCDHB14,CA2,SOAT2,FUT9,HS3ST5,FAM107B,SLC16A9,GLIS1,TNFRSF11A,TRPM4,DPYSL5,HBG2,ARAP2,KCNQ3,HNF4G,LRRIQ1,CRIM1,MCF2L2,ESRRG,STAT4,OGDHL,ASAP3,GRID1,WWC1,ATP11A,CDC42BPA,ARRDC4,PLCB1,GALNT14,HERPUD1,SMPDL3B,BAIAP2,DAGLA,PLEKHH2,SH3GL2,FAT4,FBN1,PLXDC2,SLC2A6,SVIL,MYOM2,PLD1,HK1,SHOX2,KIF1B,XKR4,SFN,CACNA2D1,FILIP1 |
| 8.496e-04 | -7.07 | scalp | COSMIC cancer mutations | scalp | 2152 | 252 | 17385 | 1698 |
ARHGAP26,MYCBP2,CGN,UGT8,CACNG3,TTC39B,GRIK2,KIF5A,ATP8A1,PTPN21,FHDC1,CHAC1,BCAN,KIAA1217,DACH2,HMCN1,TRPS1,BAG3,CPNE2,RPS6KA2,ZFYVE28,FAAH2,COL19A1,ATRNL1,PPP2R2B,PACSIN1,TMEM132E,PTPRE,OR2W3,TLR4,SLIT2,PDGFRB,DBN1,TNK2,ITGB7,SLC3A2,COL4A3,ACVR1C,DCC,SPOCD1,KLHL23,ALDH1L2,CAP2,ANK2,LRRK2,NFIA,NFE2L1,CR2,ABCC2,TNS1,KCND3,F12,SGK2,BATF,SPNS1,TMEM132B,SH3RF1,ITGBL1,ENPP6,MAP2,NCKAP1L,NCAM2,SEMA3C,PIK3C2B,TMOD2,EFNB2,BCL11B,GPT2,LRFN5,MRC2,STXBP5L,PTPRD,ZHX3,CYP2J2,DHCR24,GTF2IRD1,SETBP1,ZNF215,TNFRSF19,MECOM,PCDHB14,IL17D,RNF180,NAV1,CA2,ZNF354A,FRY,EEF2,CNTN4,ADCK1,BACE2,CACNB2,ZIC5,PRKG1,FAM107B,CPXM2,NCEH1,AGL,GLIS1,RIMS2,CAND2,GPR161,CHRM3,NOS3,EPB41L5,DPYSL5,RPL26,UNC5C,KCNQ3,COL4A4,STAT4,VLDLR,KIAA1324L,HIP1,SHISA2,PEX5L,PLCB1,SLC46A3,C4orf19,KHDRBS2,TEX15,PLEKHH2,ADAMTS3,PKN3,MFSD2A,CSF1,EMILIN2,SH3BP4,RAI14,DYNC2LI1,CDH17,PTPRN2,PLD1,SEMA3A,XKR4,MME,SFN,CREB3L2,DMXL2,PLA2G4A,ZSWIM5,SORBS1,CELSR3,RBFOX2,ARHGAP22,XYLT1,MSR1,PLXNA2,HECW2,ADD2,NTRK3,FAM198B,NRXN1,KIF21B,RADIL,COL14A1,CCDC120,SPEG,COL22A1,TLR3,KMO,PPFIBP1,ZDHHC6,ALDH1L1,ZNF521,NAP1L3,WWC2,MET,POU2F2,DNAH5,HSPA2,GAB2,VNN2,FER,MYLK3,GARS,COL6A2,FZD4,CYB5R2,KCNH5,PREX1,SATB2,VIM,TTLL7,FGFR1,MAGI3,BCL11A,ARMC4,PTPRJ,BACH2,TDO2,PTK7,GBP1,ITGA2,ABI3,PTPRS,SOHLH2,GRB10,DISP1,PLD5,HS3ST3B1,CNTN1,HACE1,OR51B5,PCDH18,FARP1,WDR17,PRSS16,ROBO2,BMPR2,CLGN,RUSC2,ATP9A,REL,NLRP14,CCNJL,CLSTN2,GABRG2,HERC5,HBE1,EPHB1,FAM174B,COL27A1,MAP1A,LRRN1,SCN1B,KIAA0319,TNFRSF11A,MED12L,CES3,MN1,VAV3,SYNPO2,AGPAT4,PTPN13,ZDHHC15,PRICKLE1,SMPDL3B,PTPRC,NSD1,TIFA,FAT4,TERT,AKT3,PGM2L1,MYOM2,PIP5KL1,RNF157,KIF1B,MMP16,ATP1A3,TPT1 |
| 8.517e-04 | -7.07 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | 340 | 52 | 17377 | 1707 |
ANKRD13D,DUSP8,SIDT1,TSPAN15,GALNT6,LMCD1,CLSTN2,GATA3,FAM110B,TBC1D30,TRPS1,SYCP2,CHN2,KCTD15,LRRN1,TRIM3,ADCY6,TSPAN13,PCK2,MYO6,LRP3,KIAA1211,FGFR4,GARS,ERGIC1,EVL,SLC37A1,FZD4,THSD4,SHANK2,DEPTOR,PREX1,MARS,C4orf19,NPDC1,TBC1D16,ARHGEF26,PYCR1,ISG20,ENPP1,ICA1,GPR160,WFS1,XBP1,ZNF704,HK2,FBRSL1,TTC39A,TC2N,FOXA1,CTNND2,ABCG1 |
| 8.530e-04 | -7.07 | BOYLAN_MULTIPLE_MYELOMA_D_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_UP | 82 | 18 | 17377 | 1707 |
SUSD3,CLYBL,ITGA6,BLVRB,DHCR24,OBSCN,GSTO1,ASPH,SPIRE1,MYC,AKT3,PLK2,CLMN,SH3BGRL2,KLF9,TLN2,DIRC2,DDIT3 |
| 8.530e-04 | -7.07 | GO_POSITIVE_REGULATION_OF_OSSIFICATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_OSSIFICATION | 82 | 18 | 17377 | 1707 |
PLA2G4A,PDLIM7,ACVR1,RUNX2,BMPR2,ZHX3,CD276,CEBPA,ACVR2B,BMP6,CEBPB,SMAD3,TFAP2A,ACVR2A,HGF,BMP4,BMPR1A,MEF2C |
| 8.530e-04 | -7.07 | GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH | 82 | 18 | 17377 | 1707 |
SEMA6B,FGF13,MSTN,DCC,WWC1,SAV1,SEMA6A,BCL11A,SEMA4F,STC2,ADRB1,SEMA3C,BMP4,WWC2,NRP1,SEMA3A,SEMA6C,TLL2 |
| 8.532e-04 | -7.07 | V$GATA_C | MSigDB lists | V$GATA_C | 244 | 40 | 17377 | 1707 |
ACVR1,ZHX3,CHCHD7,PLAG1,BLVRB,MSR1,ZNF219,TNFRSF19,SATB1,BMP6,RPL13A,MECOM,PPM1E,SRGAP1,ETV1,GATM,C15orf41,NDUFA4L2,BDNF,ARAP2,SLITRK2,ESRRG,GDPD1,LITAF,PREX1,WNT11,PLS1,ZIC1,TSKU,ZNF711,KLF12,C1orf21,B3GALT2,ZBTB20,LIFR,STON2,MID1,FRMD5,BTRC,HS6ST3 |
| 8.559e-04 | -7.06 | LSP1 (lymphocyte-specific protein 1) | protein interactions | 4046 | 32 | 10 | 17029 | 1718 |
MAPKAPK2,BAG3,GSN,MYO1D,BMPR2,PRKCB,MYO1B,TMOD2,BTRC,SCIN |
| 8.562e-04 | -7.06 | carboxylic acid metabolic process | biological process | GO:0019752 | 873 | 112 | 17256 | 1658 |
PLA2G4A,NMNAT3,ACSL1,ELOVL4,AASS,IL15,UGDH,ASS1,STAT5B,SLC7A2,ABAT,BCAN,LPIN3,AARS,CYP26A1,QPRT,ASNS,AADAT,KMO,ERO1B,FAAH2,ALDOC,ALDH1L1,MDH1B,ENO1,GATM,CTH,GLDC,CYP1B1,VNN2,SESN2,ATF4,GAPDH,GARS,UROS,CEMIP2,PFKFB2,ALDH1L2,ACO1,HACD1,PRKAR2B,GSTO1,ABCC2,SNCA,PYCR1,WARS,TDO2,PEMT,ALDOA,BDH2,TNFRSF1A,PAM,HPGD,P4HA1,DSEL,HGF,CYP2U1,PPARGC1A,PSPH,CRYL1,PRKAA2,UST,CARS,GPT2,SERINC5,ALOX5AP,EHHADH,ENO2,GCAT,CYP2J2,ST6GAL1,OLAH,ELOVL7,RIMKLA,CYP4V2,CBS,SCD,SLC1A3,PHGDH,ADSSL1,MSMO1,GHR,PHYKPL,PCK2,SYK,NOS3,FADS1,ATP5IF1,GSTM2,HYKK,SLC27A2,MGST3,ELOVL3,FASN,OGDHL,MARS,AIG1,AMDHD1,MAPKAPK2,DAGLA,DDAH1,RIMKLB,GSTO2,PLOD2,XBP1,SLC7A5,HK2,PGM2L1,HK1,PTGES,OSBPL6,ACSM3 |
| 8.563e-04 | -7.06 | superficial_spreading | COSMIC cancer mutations | superficial_spreading | 1129 | 142 | 17385 | 1698 |
EXPH5,GRIK2,ATP8A1,STAT5B,ADAMTS6,SYT14,KIAA1217,SNX9,NOVA1,SLC9A7,SLC10A7,COL19A1,PPP2R2B,CTTN,TLR4,SLIT2,RWDD2A,GDAP1,ABCC4,DCC,SPOCD1,TGFA,LRRK2,SGK2,ITGBL1,CCBE1,RASGRF2,TECPR2,ARHGAP28,CELSR1,UBASH3B,GTF2IRD1,SETBP1,LAMC3,SATB1,PCDHB14,CA2,SLC7A11,PRKG1,HS3ST5,FAM107B,SLC16A9,GLIS1,DPYSL5,HBG2,KCNQ3,STAT4,ZNF605,WWC1,AIG1,CDC42BPA,ARRDC4,PLCB1,HERPUD1,BAIAP2,DAGLA,PLEKHH2,SH3GL2,SLC2A6,CDH17,PLD1,XKR4,SFN,EPHA3,PLA2G4A,NEK10,SORBS1,CELSR3,GALNT6,MORC4,PKP2,NTRK3,KIF21B,EPB41L3,COL22A1,TLR3,SCN2A,MET,DNAH5,HSPA2,NTNG1,PTPRU,SHANK2,ADCY1,NLGN4X,DOCK5,DSP,MAGI3,FGFR1,BATF3,ARMC4,TMPRSS9,LAMB1,RCN3,MAOA,PTPRS,LIFR,CTNND2,MAST1,MAN2B2,PCDH18,ANKRD13B,DYRK3,PRSS16,CLGN,REL,MCTP2,CLSTN2,HBE1,GDPD5,SOAT2,FUT9,AFF2,TNFRSF11A,TRPM4,ARAP2,HNF4G,CRIM1,LRRIQ1,ESRRG,MCF2L2,GRID1,ASAP3,OGDHL,ATP11A,GUCY1A2,GALNT14,ILDR2,SMPDL3B,FAT4,FBN1,TERT,PLXDC2,SVIL,SLCO5A1,MYOM2,HK1,SHOX2,KIF1B,FILIP1,CACNA2D1,CRISPLD1 |
| 8.583e-04 | -7.06 | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_UP | 190 | 33 | 17377 | 1707 |
FAM171B,ANKRD13B,ALOX5AP,PPFIBP2,KCTD12,CHSY1,BBS9,NEDD4,COL27A1,FHOD3,CA2,PIK3AP1,SLCO4C1,SYK,POU3F3,SEMA6C,FGFR4,SOX21,ATOX1,MGAT4B,MSRB3,PLS1,FBXO36,DSP,PEAK1,FRK,DDAH1,TMEM150B,PCDHB7,RAB31,RNF130,CSRP2,STOM |
| 8.583e-04 | -7.06 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 190 | 33 | 17377 | 1707 |
CELSR1,SORBS3,DOCK2,CDS1,RPS6KA2,MCF2L,BCL6,CCDC122,DAB2IP,MET,DENND1C,TLR4,ENO1,CKAP4,VEGFC,PPP1R3D,EBPL,STAT4,LITAF,NUAK2,HIP1,VIM,COTL1,CRYBG3,SMPDL3B,PYCR1,PTPRC,CD37,WFS1,XBP1,PAM,NRP1,TTC39A |
| 8.596e-04 | -7.06 | SH2 domain binding | molecular function | GO:0042169 | 33 | 10 | 17224 | 1680 |
INPPL1,PTPN6,LILRB1,AFAP1L2,RACK1,SH3PXD2B,SYNGR3,SKAP1,KHDRBS2,SYK |
| 8.612e-04 | -7.06 | V$LHX3_01 | MSigDB lists | V$LHX3_01 | 213 | 36 | 17377 | 1707 |
INPPL1,JDP2,TNFSF13B,COLEC10,NOVA1,SEMA6A,SP8,ARHGAP44,NEO1,NKX6-1,KCTD15,CHN2,PRKG1,TFAP2A,HRK,MARCKS,PPP2R2B,FIGN,MED12L,EPB41L5,PCDH10,RAX,COL4A3,COL4A4,KCNH5,PACSIN3,PRDM1,ADAMTS17,ID3,GNAO1,ZBTB20,SEMA3C,NRP1,UNC5B,SHOX2,MID1 |
| 8.617e-04 | -7.06 | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_DN | 160 | 29 | 17377 | 1707 |
MICAL2,PRAME,CRIP2,BNIP3L,DUSP9,FERMT2,IL13RA1,BCAN,EPHB1,C9orf116,MECOM,SNCA,GSN,ICA1,TACC2,HEYL,THBS4,SERINC2,RAB31,PTPRS,STEAP3,PCOLCE2,RPL4,PROS1,TPM1,LZTS1,TESC,TPT1,RRAGD |
| 8.617e-04 | -7.06 | AKT_UP.V1_UP | MSigDB lists | AKT_UP.V1_UP | 160 | 29 | 17377 | 1707 |
MAN2B2,PAK1,CD55,UGT8,PDK1,C3orf52,LDLR,DHCR24,PACSIN3,GTF2IRD1,AK4,ATF3,CYP51A1,MMP15,RIMKLB,PTPRJ,IDI1,PLAGL1,MSMO1,BACE2,ALDOC,PLK2,CLMN,SH3BGRL2,UNC5B,HOXB9,DHCR7,TESC,TMEM56 |
| 8.631e-04 | -7.05 | V$OLF1_01 | MSigDB lists | V$OLF1_01 | 252 | 41 | 17377 | 1707 |
SLC6A9,CMTM8,PTPN21,ITPR2,GAS6,BEX2,ARHGAP44,NEO1,MECOM,TRPS1,RND2,PPFIA2,ALDOC,PCBP4,GHR,SHF,SGK1,ADCY6,EPHB6,GFRA1,TMEM56,PDGFRB,DPYSL5,PPP1R3D,MEIS2,PTPN6,CACNA1E,ESRRG,FGF12,CTTNBP2NL,SDK1,MAP1B,ZNF711,MMP15,ENTPD1,ENTPD7,GRIN2D,HOXD13,BMP4,TPM1,HACE1 |
| 8.640e-04 | -7.05 | MODULE_122 | MSigDB lists | MODULE_122 | 138 | 26 | 17377 | 1707 |
COL9A3,ITGB7,COL6A2,FN1,SELL,COL18A1,COL4A5,APBA1,NEO1,ITGBL1,FBN1,RND3,PTK7,THBS4,FAT1,PPFIBP1,DSG2,ITGA2,LAMB1,CDH17,PTPRS,NRP1,NCAM1,CDH2,JAM2,COL9A2 |
| 8.662e-04 | -7.05 | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 373 | 56 | 17377 | 1707 |
DNM3,ID1,GPR65,BIK,CLSTN2,ARL2,SORBS3,NTRK3,EPHB1,NRXN1,PRKCA,SNX9,PFN2,CBLN1,SPIRE1,SCIN,PPM1E,UNC13B,LRRN1,PMAIP1,FLRT3,GTF2F2,HRK,CTTN,TLR4,FES,PAK1,EPB41L5,BDNF,PHLDB2,FER,GPM6A,RHOQ,MYLK3,EVL,SLITRK2,SLITRK5,WNT11,PRKCQ,AMIGO1,TLR6,BAIAP2,SMAD3,GSN,PTPRJ,NCKAP1L,MPP7,CDH17,BBC3,ERCC5,OXTR,TPM1,FNBP1L,MAGI2,CDH2,COBL |
| 8.664e-04 | -7.05 | PHONG_TNF_RESPONSE_NOT_VIA_P38 | MSigDB lists | PHONG_TNF_RESPONSE_NOT_VIA_P38 | 324 | 50 | 17377 | 1707 |
CARS,TNIK,DUSP8,TRIM16,PLEKHA5,DNAJC3,LDLR,LRRC49,SLCO3A1,PHLDA2,MTUS1,GATA2,PDE10A,PRKCD,SGK1,TOX,ETV1,ZFP36L2,IGSF3,MEIS2,COL6A2,MVD,RAPGEF2,ARID5B,MGAT4B,NFE2L1,ATP1B1,STEAP1,GNAI1,CEBPB,SMAD3,IRS2,TRIB3,CXCL10,GPRC5B,GBP1,P4HA2,CSF1,ITGA2,SLC2A6,INPP4B,SH3BP4,RAI14,OXTR,GEM,THAP10,MID1,PTGES,MEF2C,HEY1 |
| 8.666e-04 | -7.05 | GO_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_KINASE_ACTIVITY | 618 | 85 | 17377 | 1707 |
EPHA3,BTC,NEK10,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,KCNH5,LRRK2,PRKCQ,ACVR2B,FGF17,ROR1,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PTK7,PLK2,ERN1,MAPK13,BMPR1A,NRP1,MAPK10,MAST1,PRKAA2,TYRO3,LATS2,TNIK,DYRK3,BMPR2,SLK,PKN1,EPHB1,EFEMP1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,PRKG2,SGK1,ALPK1,MAST4,SYK,FES,FGFR4,PAK1,CRIM1,EFNA3,NUAK2,STRADB,OBSCN,CDC42BPA,PEAK1,MAPKAPK2,FGR,PKN3,AKT3,MAP2K6,NEK11,LRRK1 |
| 8.784e-04 | -7.04 | salivary_gland | COSMIC cancer mutations | salivary_gland | 1157 | 145 | 17385 | 1698 |
MVK,CACNG3,ACVR1,NPM1,CADM2,PRKCA,SLC9A7,STK24,TYMP,FKBP9,SIPA1L2,RPS6KA2,OR2W3,PRKACB,PDGFRB,TNK2,EML6,SMAD9,TGFA,KLHL4,ACVR2B,FHAD1,AK1,MAP2,NCAM2,PLK2,GNB4,ATP7B,MAPK13,ERCC5,PIK3C2B,TANC2,MAGI2,KLF8,LATS2,STOX2,MRC2,RUNX2,ZNF395,CHCHD7,WDFY4,APBA1,IGF1R,FRAS1,PRKG1,OPN3,RNF148,PAK1,FGFR4,IL17RD,MYO10,GSTM4,ARID5B,KIAA1324L,SPATA13,RYR2,OBSCN,PDE8A,CDC42BPA,SPATA7,DAGLA,MAPKAPK2,TEX15,CECR2,HK2,NXPH4,CELSR3,ZNF311,NTRK3,CHUK,GRK6,DDR1,DDX60L,CBLN1,TXNRD3,ZNF827,SPEG,COL22A1,RPS6KL1,LHX6,ACVR2A,NAP1L3,MET,DNAH5,MYT1,NTNG1,DOCK8,ALG10B,PDK1,ATP1B1,FGFR1,CAMK2N1,PTPRJ,LMLN,PRKCB,PTK7,KLF5,BMPR1A,KLHL31,CTTNBP2,LIFR,CTNND2,PCDH18,TNIK,CCDC148,PLAG1,NOTUM,TSPAN17,ARHGAP44,NEO1,FSD1,FOXP2,CHN2,AFF2,TFAP2A,SGK1,ERRFI1,SYK,FES,BCL7A,RIN2,ARAP2,ARHGEF28,CRIM1,AGPAT4,CACNA1E,ELOVL3,AK4,GUCY1A2,PALLD,NSD1,TRIB3,FGR,ICA1,TMEM237,FAT4,FBN1,AKT3,MAP2K6,MYOM2,HK1,TBC1D4,DDIT3,FILIP1,ATP2B4 |
| 8.791e-04 | -7.04 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | MSigDB lists | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | 398 | 59 | 17377 | 1707 |
TYRO3,PAGE1,MRC2,IL32,ST14,GCAT,ZCCHC24,GALNT6,MCOLN3,SSX1,CLSTN2,SCD,CHAC1,KIF21B,NOS1AP,QPRT,EFEMP1,RGS17,ASNS,SLC7A11,PMAIP1,LHX6,BNIP3,FAM155A,HSPA2,BARX1,CYP1B1,B4GALT6,IGFBP3,GLDC,PFKFB4,MSX1,CD55,PDK1,COL4A3,TES,CYB5R2,AGPAT4,DNAJC6,RAB38,SNAP25,SNTB1,HOXA1,TSKU,ISG20,SMAD3,ARMC4,MAGEA12,GYPC,CSF1,RAB31,CDH17,RCN3,MAOA,SVIL,SUSD4,SFN,HEY1,PHC1 |
| 8.798e-04 | -7.04 | BROWNE_HCMV_INFECTION_14HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_DN | 276 | 44 | 17377 | 1707 |
FGF13,PRSS12,ZCCHC24,BLVRB,MYO1B,LDLR,RGS20,TJP1,GPSM2,DENND3,GAS1,MECOM,MAP1A,CDC14B,SLC16A2,STC2,SLC6A15,TOX,MARCKS,MET,RAB27B,RRAS2,SMAD6,ETV1,ZFP36L2,CAND2,CEBPD,CYP1B1,VEGFC,MICAL2,MYO10,CAP2,CACNA1E,SLITRK5,MGMT,DKK1,SMAD3,TERT,ITGA2,INPP4B,DYNC2LI1,AHNAK2,ATG5,MMP16 |
| 8.835e-04 | -7.03 | regulation of alcohol biosynthetic process | biological process | GO:1902930 | 64 | 15 | 17256 | 1658 |
CYP51A1,IDI1,MVK,HMGCS1,MVD,SREBF1,FASN,SQLE,SCD,P2RY1,DHCR7,GFI1,ABCG1,HMGCR,SNCA |
| 8.848e-04 | -7.03 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | molecular function | GO:0001077 | 278 | 44 | 17224 | 1680 |
CREB3L2,BCL11B,RUNX2,PLAG1,OTX1,GATA3,STAT5B,CEBPA,GRHL1,GATA2,MYC,SREBF1,TFAP2A,EBF4,POU2F2,ETV1,CEBPD,RAX,ATF4,MEIS2,HNF4G,NR6A1,SOX21,NR4A1,NFIA,LITAF,MAFB,MEF2B,SATB2,ATOH1,BATF,ZIC1,EBF1,CEBPB,HLF,HEYL,HOXD13,KLF5,DBP,NKX2-8,SIX2,FOXA1,DDIT3,MEF2C |
| 8.856e-04 | -7.03 | positive regulation of gamma-delta T cell differentiation | biological process | GO:0045588 | 3 | 3 | 17256 | 1658 |
STAT5B,NCKAP1L,SYK |
| 8.856e-04 | -7.03 | condensed mesenchymal cell proliferation | biological process | GO:0072137 | 3 | 3 | 17256 | 1658 |
FAT4,SIX2,DCHS1 |
| 8.856e-04 | -7.03 | membrane depolarization during Purkinje myocyte cell action potential | biological process | GO:0086047 | 3 | 3 | 17256 | 1658 |
TRPM4,SCN5A,SCN1B |
| 8.856e-04 | -7.03 | membrane depolarization during bundle of His cell action potential | biological process | GO:0086048 | 3 | 3 | 17256 | 1658 |
TRPM4,SCN5A,CACNA2D1 |
| 8.856e-04 | -7.03 | Purkinje myocyte action potential | biological process | GO:0086017 | 3 | 3 | 17256 | 1658 |
TRPM4,SCN5A,SCN1B |
| 8.878e-04 | -7.03 | synaptic vesicle cycle | biological process | GO:0099504 | 112 | 22 | 17256 | 1658 |
DOC2A,DNM3,SYT12,DNAJC6,OPHN1,NLGN4X,SNAP25,CANX,SYT14,PCLO,SNCA,TRIM9,SH3GL2,UNC13B,FCHO2,CADPS2,SEPT5,PACSIN1,TC2N,STON2,RIMS2,SNPH |
| 8.884e-04 | -7.03 | breast-carcinoma-lobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-lobular_carcinoma | 771 | 102 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,GATA3,NPM1,CHUK,CEBPA,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,BCL6,ACVR2A,CTTN,MET,PRKACB,PDGFRB,NKX2-1,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,NR6A1,KLHL4,LRRK2,PRKCQ,VIM,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,ZNF396,IRS2,SMAD3,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PCSK5,PRKAA2,TNIK,LATS2,KLF8,DYRK3,MXI1,BMPR2,PTPRD,ARHGEF11,ITPRIP,CMTM8,WDFY4,PKN1,EPHB1,IGF1R,ADCK1,SCN1B,MYC,PRKCD,SGK3,PRKG1,LRP6,SGK1,ALPK1,SYK,ATP2B1,FES,PAK1,PTCH2,FGFR4,CACNA1E,NUAK2,OBSCN,STRADB,CDC42BPA,SNTB1,GUCY1A2,RERE,MAPKAPK2,CACHD1,NSD1,TRIB3,FGR,TERT,PKN3,AKT3,MAP2K6,NEK11,PLD1,SHOX2,CDH2 |
| 8.884e-04 | -7.03 | lobular_carcinoma | COSMIC cancer mutations | lobular_carcinoma | 771 | 102 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,GATA3,NPM1,CHUK,CEBPA,NTRK3,GRK6,PRKCA,DDR1,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,BCL6,ACVR2A,CTTN,MET,PRKACB,PDGFRB,NKX2-1,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,NR6A1,KLHL4,LRRK2,PRKCQ,VIM,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,ZNF396,IRS2,SMAD3,PRKCB,PLK2,PTK7,ERN1,MAPK13,BMPR1A,MAST1,PCSK5,PRKAA2,TNIK,LATS2,KLF8,DYRK3,MXI1,BMPR2,PTPRD,ARHGEF11,ITPRIP,CMTM8,WDFY4,PKN1,EPHB1,IGF1R,ADCK1,SCN1B,MYC,PRKCD,SGK3,PRKG1,LRP6,SGK1,ALPK1,SYK,ATP2B1,FES,PAK1,PTCH2,FGFR4,CACNA1E,NUAK2,OBSCN,STRADB,CDC42BPA,SNTB1,GUCY1A2,RERE,MAPKAPK2,CACHD1,NSD1,TRIB3,FGR,TERT,PKN3,AKT3,MAP2K6,NEK11,PLD1,SHOX2,CDH2 |
| 8.899e-04 | -7.02 | regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070302 | 218 | 36 | 17256 | 1658 |
PRKN,TNIK,EDA2R,GRIK2,FZD8,PKN1,EPHB1,TPD52L1,TNFRSF19,MECOM,TGFBR3,TLR3,IGF1R,DACT1,MYC,RAP2A,INAVA,DAB2IP,TNFRSF11A,SYK,RASGRP1,HMGCR,PAK1,FZD4,TLR6,PLCB1,MAGI3,DKK1,SH3RF1,ERN1,DUSP19,MAP3K21,HGF,SEMA3A,MAP3K20,MID1 |
| 8.944e-04 | -7.02 | MODULE_317 | MSigDB lists | MODULE_317 | 390 | 58 | 17377 | 1707 |
SV2B,MOCOS,ACVR1,ACSL1,FN1,AASS,SLC25A27,BEGAIN,HBE1,SCD,MAPK4,PRDM8,ISYNA1,CBLN1,IL18R1,BAG3,EPHB6,IPCEF1,PDE4D,FAR2,TBC1D9,LRP3,SP140L,MED12L,KDM5B,TBC1D8B,KLHL4,HOMER2,WDR25,OBSCN,SDC3,AGAP2,PRDM1,TMEM47,AMIGO1,SAV1,FGFR1,RERE,DEXI,SMAD3,SPNS1,CXCL10,GSN,MAP2K6,CCBE1,CSF1,ABI3,WDR19,NCOA7,DYNC2LI1,PLEKHG1,NXPH4,GEM,TNFSF4,LARP1,PKIA,SLC43A1,RRAGD |
| 8.952e-04 | -7.02 | main axon | cellular component | GO:0044304 | 65 | 15 | 18223 | 1724 |
TUBB4A,DAGLA,EPB41L3,MYO1D,NAV1,KCNAB1,KCNQ3,ROBO2,SCN1B,MAP2,SCN8A,APBB1,DLG2,SCN2A,CD40 |
| 8.982e-04 | -7.02 | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_PARTIAL | 153 | 28 | 17377 | 1707 |
EFNB2,BDNF,ID1,ZNF395,REL,TGFA,C3orf52,LDLR,LITAF,WWC1,INTS6,RNF44,HERPUD1,PCDH7,SNCA,DKK1,SMAD3,SLC39A14,ID3,INSIG1,PMAIP1,PLK2,FLRT3,BCL6,SEMA3C,CEBPD,DUSP1,HEY1 |
| 8.982e-04 | -7.02 | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 153 | 28 | 17377 | 1707 |
PLA2G4A,SERINC5,EHHADH,ALOX5AP,MSTN,TBC1D1,CACNA1E,PTPN6,ST6GAL1,RAPGEF4,MCTP2,UBAC2,HIP1,PHACTR2,CEBPA,KIF21B,SLC46A3,TSPAN17,SPIRE1,KMO,FAM168A,GPR155,ITGA2,NCOA7,DAB2IP,ALPK1,CERS4,PTPRE |
| 8.995e-04 | -7.01 | GO_REGULATION_OF_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_CELL_PROLIFERATION | 1434 | 176 | 17377 | 1707 |
GATA3,LILRB1,NPM1,NDRG2,CTBP2,CEBPA,STAT5B,PRKCA,F3,SKI,EPCAM,TGFBR3,RPS6KA2,PMAIP1,DLX6,ITGB3,TLR4,TSHR,POU3F3,PDGFRB,TBC1D8,CYP1B1,TNK2,CD55,GCNT2,SKAP2,COL4A3,ACVR1C,TGFA,LRRK2,YAP1,FGF17,SAV1,SGK2,SESN1,HPSE,NCKAP1L,TNFRSF1A,NRP1,TPM1,TNFSF4,PPARGC1A,VASH2,MAGI2,MEF2C,BCL11B,EFNB2,SCN5A,INPPL1,RUNX2,LGALS3,FN1,ST6GAL1,DHCR24,TNFRSF10C,CHD5,EFEMP1,IGF1R,BCHE,GATA2,MYC,C1QL4,LRP6,ST8SIA1,NOS3,HMGCR,FGFR4,PAK1,DISC1,PNP,MSTN,CALCRL,SMARCD3,PRDM1,CPEB1,CSF1,THBS4,SH3BP4,CLMN,EGFL7,HOXD13,DHCR7,CDH2,NKX2-8,TESC,SFN,SIX2,PLA2G4A,BTC,ID1,IL15,RBFOX2,PKP2,COL18A1,NTRK3,DDR1,SCIN,SPEG,FABP6,BCL6,DAB2IP,SNAI2,GLI1,IGFBP3,GAB2,INTU,FER,PRAME,PTPRU,PTPN6,MVD,TES,ATF3,WNT11,PRKCQ,SYNJ2BP,CD40,FRK,ASPH,FGFR1,WARS,SMAD3,IRS2,CXCL10,PTPRJ,IKZF3,PEMT,WWTR1,ITGA2,LAMB1,HGF,BMPR1A,LIFR,MXI1,IGFBP6,BMPR2,CD276,PLAG1,TNFSF13B,GAS6,OVOL2,PKN1,BMP6,FOXP2,SGK3,TFAP2A,SGK1,KLF9,IQGAP3,ERRFI1,SMAD6,TNFRSF11A,SPRY2,SYK,FES,TRPM4,VEGFC,VAV3,MSX1,KDM5B,NR4A1,RAPGEF2,CRIP2,GPLD1,CEBPB,PTPRC,FGR,NACC2,TERT,ACER2,XBP1,MCC,BMP4,SHOX2,PTGES,B4GALT7 |
| 9.001e-04 | -7.01 | ion gated channel activity | molecular function | GO:0022839 | 335 | 51 | 17224 | 1680 |
KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,KCNIP3,KCNQ3,KCNH5,CACNA1E,JPH1,GRID1,CHRNA6,TTYH2,RASA3,RYR2,KCND3,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,CACNA2D1 |
| 9.029e-04 | -7.01 | GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | MSigDB lists | GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 767 | 102 | 17377 | 1707 |
EPHA3,SORBS1,ID1,IL15,ASS1,LILRB1,STAT5B,NTRK3,ITPR2,F3,FBXO32,RPS6KA2,AKAP7,DAB2IP,PDE4D,TLR4,SLIT2,PRKACB,CYP1B1,FZD1,FER,FZD4,LRRK2,ADCY1,YAP1,WNT11,PRKAR2B,PLEKHA1,CD40,GNAI1,SNCA,IRS2,CXCL10,ENPP1,PRKCB,PTK7,GNB4,EIF4EBP1,ITGA2,ERN1,RGS10,GRB10,PPARGC1A,TNFSF4,TPM1,MEF2C,RRAGD,PRKAA2,GNG12,PLSCR4,FN1,IPO5,ATP6V1E2,GAS6,MLC1,NKX6-1,RAB11FIP5,HMGCS1,CA2,IGF1R,GHR,PRKCD,SREBF1,ADCY6,LRP6,BNIP3,KLF9,ERRFI1,GFI1,ATP2B1,CHRM3,NOS3,PAK1,PXN,RHOQ,MSTN,NR4A1,RAPGEF2,VLDLR,LITAF,RYR2,CALCRL,PLCB1,BAIAP2,CPEB1,GPLD1,CEBPB,ID3,TRIB3,FBN1,MAP2K6,XBP1,PCGF2,SH3BP4,RAB31,PTPRN2,CMPK2,CERS1,TBC1D4,TESC,SMYD3,ATP2B4 |
| 9.067e-04 | -7.01 | GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_UP | MSigDB lists | GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_UP | 183 | 32 | 17377 | 1707 |
INPPL1,SORBS1,HEBP1,ITGA6,LCP2,PCLO,MECOM,FKBP9,ALDOC,ALDH1L1,SGK1,GSTM3,SLC6A15,KLF9,SH3PXD2B,CERS4,TBC1D9,RAB27B,FKBP14,ATF4,SLC37A1,ISG20,BEX4,SUGT1,PKN3,PLXDC2,PRCP,BDH2,RAI14,GRB10,PPARGC1A,GEM |
| 9.067e-04 | -7.01 | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | MSigDB lists | REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | 183 | 32 | 17377 | 1707 |
GNG12,ALDH2,CACNG3,GRIK2,AKAP5,GABRB2,ADCY1,GABRG2,CHRNA6,GABRR2,ABAT,SLC1A3,SNAP25,PRKCA,CACNB4,PLCB1,GNAI1,GRIK4,KCNJ4,RPS6KA2,UNC13B,CHRNA5,PRKCB,CACNB2,GNB4,RASGRF2,MAOA,ADCY6,GRIN2D,MYO6,STXBP1,PRKACB |
| 9.067e-04 | -7.01 | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | 183 | 32 | 17377 | 1707 |
ANKRD13D,TTC39B,EDA2R,ADD2,TNKS1BP1,GAS1,HOPX,GPR15,SYCP2,CPNE2,CPVL,GTSF1,SCRN1,MARCH3,NTNG1,SMPDL3A,GLDC,OPLAH,MEIS2,MVD,MGAT4B,MSRB3,RAB38,BATF,EML1,SNCA,HTR7,GSTO2,MYADM,WFS1,RAB31,NKX2-8 |
| 9.067e-04 | -7.01 | GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_UP | MSigDB lists | GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_UP | 183 | 32 | 17377 | 1707 |
ENO2,C20orf194,IL13RA1,SCD,TMEM170B,CHAC1,DDR1,PCDH7,RND2,KIAA0895,KAZN,REEP1,RAP2A,GSTM3,SLC6A15,NCAM1,STXBP1,FAM155A,FAM78B,SNX7,RAB3B,DCHS1,STRADB,C1R,ZNF558,CCNA1,RAI14,PGM2L1,RNF157,KCTD1,MAST1,ATP1A3 |
| 9.067e-04 | -7.01 | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 183 | 32 | 17377 | 1707 |
CCDC126,LCA5,SORBS1,PTPN13,GJB2,TMEM126A,CR2,COBLL1,PHACTR2,PRDM1,ARRDC4,SLC46A3,ATP10D,GPLD1,SMAD3,GPR15,ENPP1,TMEM154,IKZF3,PTPRJ,SOAT2,GRHL1,GPR155,RBPMS2,CERS4,IPCEF1,PTPRE,SHOX2,RAPGEF5,CSRP2,SNAI2,SMPDL3A |
| 9.088e-04 | -7.00 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP | 33 | 10 | 17377 | 1707 |
TRIB3,LATS2,CD55,PLAGL1,EIF1,RHPN2,SQLE,SPRY4,ERRFI1,ABHD4 |
| 9.095e-04 | -7.00 | AH/BAR_dom_sf | interpro domains | IPR027267 | 76 | 17 | 18492 | 1811 |
ARHGAP26,FER,PSTPIP2,ASAP3,PACSIN3,OPHN1,SNX9,ARHGAP44,BAIAP2,ICA1,SH3GL2,FCHO2,SRGAP1,PACSIN1,FNBP1L,FES,SNX7 |
| 9.099e-04 | -7.00 | regulation of hydrolase activity | biological process | GO:0051336 | 1270 | 155 | 17256 | 1658 |
ARHGAP26,PHACTR3,PPP4R4,RECK,NPM1,FAM13A,SNX9,F3,ADPRHL1,SIPA1L2,PPP1R26,PMAIP1,PPP2R2B,PCOLCE2,RCAN3,SLIT2,RASGRP1,PDGFRB,LAMP3,TBC1D8,TNK2,COL4A3,ACVR1C,SPOCD1,LRRK2,ELMOD1,GSN,SH3RF1,NCKAP1L,ERN1,ADRB1,ARHGAP28,BBC3,SERPINI1,TPM1,NRP1,MAGI2,SPOCK3,MEF2C,PCSK5,RGS16,FN1,STXBP5L,TBC1D1,BVES,ITGA6,DHCR24,OPHN1,TNFRSF10C,DYNC1I1,SPINK5,PFN2,CHN1,MYC,PRELID1,SRGAP1,PRKG1,NOS3,BOD1,ATP5IF1,TBC1D8B,EFNA3,GPSM1,RYR2,HIP1,PLCB1,FAM162A,HERPUD1,TBC1D2,ADGRB3,SH3BP4,PTPRN2,SFN,DOCK9,EPHA3,PCSK1N,RASAL2,DOCK1,GPR65,C4A,ARHGAP22,PLXNA2,RGS20,NTRK3,TBC1D30,DOCK2,TIAM2,TBC1D19,MAGEA3,BCL6,DAB2IP,PROS1,SERPINH1,HSPA2,PERP,DOCK8,IGFBP3,GAPDH,CSN2,PREX1,WNT11,ATP1B1,CD40,TBC1D16,ASPH,FGFR1,SNCA,SMAD3,ARHGAP21,RANBP2,BEX3,ITGA2,RGS10,TNFSF15,HGF,ARFGEF3,MYO1D,LPAR2,FARP1,ARHGEF11,IPO5,ARL2,GAS6,RGS7,PPP2R3A,ARHGAP44,SYDE2,RGS17,CHN2,PRKCD,RALGAPA2,TBC1D9,ERRFI1,IQGAP3,SPRY2,PCSK6,RIN2,VAV3,ARAP2,CRIM1,RAPGEF2,ASAP3,RASA3,PHACTR2,AGAP2,ARHGAP32,RACK1,LEPR,MGMT,GPLD1,DOCK7,ACER2,GNAO1,DLG2,TBC1D4 |
| 9.108e-04 | -7.00 | NUFIP1 (NUFIP1, FMR1 interacting protein 1) | protein interactions | 26747 | 114 | 23 | 17029 | 1718 |
DPYSL5,GPM6A,DNM3,RAB3B,TRIM2,RAB6B,ANK2,PLXNA2,ADD2,PRKAR2B,CADM2,SNAP25,SFXN3,HPCAL4,NCS1,SNCA,MAP1A,MAP2,GNAO1,NCAM1,STXBP1,CPE,CNTN1 |
| 9.110e-04 | -7.00 | GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP | MSigDB lists | GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP | 168 | 30 | 17377 | 1707 |
CREB3L2,TNIK,SKAP2,FBXO4,UBASH3B,ITGA6,ATF7IP2,PRKCQ,PRKCA,SKAP1,BBS9,DOCK2,METAP1D,TPK1,SLC7A1,ATXN7L1,TECPR1,KLF12,PRKCB,RASGRF2,RALGAPA2,NBEA,ZBTB20,PPP2R2B,TANC2,C15orf41,SMYD3,BTRC,LPP,PCSK5 |
| 9.134e-04 | -7.00 | V$AMEF2_Q6 | MSigDB lists | V$AMEF2_Q6 | 237 | 39 | 17377 | 1707 |
INPPL1,RUNX2,CACNG3,FGF13,RHOBTB1,LMCD1,CTBP2,CREB5,NEDD4,MTUS1,RTN1,ZNF362,BACE2,CHRDL1,HS3ST5,ACVR2A,BEND4,PPP2R2B,ETV1,BDNF,SSH3,USP2,MSTN,NR4A1,ESRRG,PACSIN3,MBNL2,TBC1D16,DKK1,HTR7,IFT81,KPNA3,GNAO1,DLG2,PPARGC1A,SEMA3A,MID1,FILIP1,CNTN1 |
| 9.171e-04 | -6.99 | positive regulation of cellular component movement | biological process | GO:0051272 | 519 | 72 | 17256 | 1658 |
AMOTL1,ACVR1,DOCK1,RHOD,ATP8A1,COL18A1,GATA3,NTRK3,PRKCA,SEMA6A,NOS1AP,F3,TCAF2,ITGB3,BCL6,DAB2IP,MET,DOCK8,SNAI2,PDGFRB,FER,GCNT2,PREX1,FEZ1,WNT11,RARRES2,CD40,DOCK5,FGFR1,IRS2,SMAD3,CXCL10,NCKAP1L,CCBE1,PLK2,APELA,ITGA2,LAMB1,HGF,SEMA3C,NRP1,FN1,LGALS3,BMPR2,ITGA6,GAS6,IGF1R,SEMA4F,GATA2,RRAS2,SPRY2,NOS3,VEGFC,TRPM4,PAK1,EPB41L5,RAPGEF2,RACK1,GPLD1,PTPRC,FGR,DOCK7,MYADM,RIPOR2,TERT,AKT3,CSF1,THBS4,XBP1,BMP4,SEMA3A,SHTN1 |
| 9.173e-04 | -6.99 | adenoid_cystic_carcinoma | COSMIC cancer mutations | adenoid_cystic_carcinoma | 1140 | 143 | 17385 | 1698 |
MVK,CACNG3,ACVR1,NPM1,CADM2,PRKCA,SLC9A7,STK24,TYMP,FKBP9,SIPA1L2,RPS6KA2,OR2W3,PRKACB,PDGFRB,TNK2,EML6,SMAD9,TGFA,KLHL4,ACVR2B,FHAD1,AK1,MAP2,NCAM2,PLK2,GNB4,ATP7B,MAPK13,ERCC5,PIK3C2B,TANC2,MAGI2,KLF8,LATS2,STOX2,MRC2,RUNX2,ZNF395,CHCHD7,WDFY4,IGF1R,FRAS1,PRKG1,OPN3,RNF148,PAK1,FGFR4,IL17RD,GSTM4,ARID5B,KIAA1324L,SPATA13,RYR2,OBSCN,PDE8A,CDC42BPA,SPATA7,DAGLA,MAPKAPK2,TEX15,CECR2,HK2,NXPH4,CELSR3,ZNF311,NTRK3,CHUK,GRK6,DDR1,DDX60L,CBLN1,TXNRD3,ZNF827,SPEG,COL22A1,RPS6KL1,LHX6,ACVR2A,NAP1L3,MET,MYT1,DNAH5,NTNG1,DOCK8,ALG10B,PDK1,ATP1B1,FGFR1,CAMK2N1,PTPRJ,LMLN,PRKCB,PTK7,KLF5,BMPR1A,KLHL31,CTTNBP2,LIFR,CTNND2,PCDH18,TNIK,CCDC148,PLAG1,NOTUM,TSPAN17,ARHGAP44,NEO1,FSD1,FOXP2,CHN2,AFF2,TFAP2A,SGK1,ERRFI1,SYK,FES,BCL7A,RIN2,ARAP2,ARHGEF28,CRIM1,AGPAT4,CACNA1E,ELOVL3,AK4,GUCY1A2,PALLD,NSD1,TRIB3,FGR,ICA1,TMEM237,FAT4,FBN1,AKT3,MAP2K6,MYOM2,HK1,TBC1D4,DDIT3,FILIP1,ATP2B4 |
| 9.242e-04 | -6.99 | WWC3 (WWC family member 3) | protein interactions | 55841 | 9 | 5 | 17029 | 1718 |
YAP1,WWC1,LATS2,WWC2,PRKCA |
| 9.263e-04 | -6.98 | EPPERT_HSC_R | MSigDB lists | EPPERT_HSC_R | 110 | 22 | 17377 | 1707 |
GCNT2,PLSCR4,RUNX2,PNP,CRIM1,RNF125,SEL1L3,FGFR1,HOPX,MECOM,BCL11A,HLF,RIMKLB,INSIG1,MSMO1,PDE10A,CACNB2,PAM,INPP4B,MLLT3,LPP,TPT1 |
| 9.329e-04 | -6.98 | SAM_DOMAIN | prosite domains | PS50105 | 77 | 18 | 12060 | 1278 |
EPHA3,ARAP2,INPPL1,SHANK2,PPFIBP2,PPFIA4,EPHB1,PPP1R9A,L3MBTL4,PPFIBP1,PPFIA2,CNKSR3,KAZN,SAMD11,SAMD13,EPHB6,MAP3K20,PHC1 |
| 9.346e-04 | -6.98 | MODULE_112 | MSigDB lists | MODULE_112 | 253 | 41 | 17377 | 1707 |
WASF3,UGT8,EHHADH,PTPRD,GRB14,CYP2J2,ST6GAL1,NTRK3,SLC1A3,RGS7,EPHB1,MLC1,NOVA1,CBLN1,GAS1,NEO1,F3,RPS6KA2,GATA2,SMTN,GSTM3,HRK,POU2F2,GATM,CYP1B1,TGFA,FHL2,PRKCQ,C1R,ROR1,RND3,GBP1,CDH17,HPGD,PTPRS,KLF5,CDH2,PKIA,SFN,ACSM3,MEF2C |
| 9.356e-04 | -6.97 | cerebral cortex neuron differentiation | biological process | GO:0021895 | 23 | 8 | 17256 | 1658 |
DLX2,EOMES,GDPD5,CHD5,RAC3,LHX6,OPHN1,NKX2-1 |
| 9.379e-04 | -6.97 | C2_Dock-C | interpro domains | IPR037808 | 3 | 3 | 18492 | 1811 |
DOCK7,DOCK6,DOCK8 |
| 9.394e-04 | -6.97 | actin-based cell projection | cellular component | GO:0098858 | 198 | 33 | 18223 | 1724 |
FARP1,INPPL1,FGF13,ITGA6,APBB1,EPS8,MYO1B,ENAH,EPHB1,PPP1R9A,TIAM2,CA2,PDZD7,ITGB3,MYO3B,ACTA2,NPTXR,MYO6,MORN4,GPM6A,MYO10,MPP1,LRRK2,HOMER2,SPATA13,BAIAP2,RIPOR2,MAP2,FAT1,CTSV,OXTR,FOXA1,SHTN1 |
| 9.395e-04 | -6.97 | LINDVALL_IMMORTALIZED_BY_TERT_DN | MSigDB lists | LINDVALL_IMMORTALIZED_BY_TERT_DN | 76 | 17 | 17377 | 1707 |
ENO2,FN1,FAM84A,CRIP2,CAPN5,LMCD1,TMEM47,MAP1B,SLC7A1,FBXO32,PLOD2,PTK7,CCBE1,CPXM2,SH3PXD2B,ARL4D,PTGES |
| 9.419e-04 | -6.97 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_UP | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_UP | 191 | 33 | 17377 | 1707 |
LCA5,TTC39B,ENO2,BMPR2,GCAT,CRIM1,JDP2,STAT4,ITGA6,CYTH3,TMTC4,RYR2,PRICKLE1,NRN1,STAT5B,ZNF219,CA8,TTC28,ABHD6,TBC1D30,SKI,TEX15,PMEPA1,MCF2L,HK2,PTPRS,INPP5F,KLF9,DBP,PURG,CSRP2,RRAGD,PHC1 |
| 9.419e-04 | -6.97 | GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_UP | MSigDB lists | GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_UP | 191 | 33 | 17377 | 1707 |
BCL11B,LATS2,GCAT,ST6GAL1,ASS1,KBTBD11,PFN2,SKI,CYP51A1,ATXN7L1,BAG3,TGFBR3,ITGB3,ACVR2A,EPHB6,PCK2,MYO6,RCAN3,PFKFB4,ATL1,VAV3,TMEM65,SAV1,TMEM154,AKT3,XBP1,INPP5F,DSEL,NRP1,TBC1D4,SLFN5,KIF1B,TESC |
| 9.419e-04 | -6.97 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | 191 | 33 | 17377 | 1707 |
MAN2B2,MYCBP2,MXI1,INPPL1,ZNF395,ATP8A1,ST6GAL1,SELL,STAT5B,FAM13A,SATB1,RPL13A,CPVL,IPCEF1,ZFP36L2,CEBPD,FES,RPL26,ALDH2,LRMP,RPL21,SMARCD3,LHPP,RNF44,RERE,ENTPD1,CD37,NACC2,PELI2,CLMN,KIAA0513,RPL4,MEF2C |
| 9.419e-04 | -6.97 | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP | 191 | 33 | 17377 | 1707 |
RUNX2,IGFBP6,LGALS3,HEBP1,TNFSF13B,MAPK4,FAM198B,ABHD6,GPR15,FKBP9,NUMBL,SEMA4F,DENND1C,MED12L,EPB41L5,PFKFB4,SUSD3,GDAP1,PXN,MYO10,ELMOD1,HIP1,KHDRBS2,DOCK5,HOXA1,JAM3,SNCA,CEBPB,MSC,ADAMTS3,CSF1,PTPRN2,B4GALT7 |
| 9.532e-04 | -6.96 | metal ion transport | biological process | GO:0030001 | 616 | 83 | 17256 | 1658 |
CACNG3,FGF13,MCOLN3,ITPR2,CACNB4,SLC9A7,NCS1,KCNAB1,KCNN2,SLC10A7,KCNS3,TRPC1,CNNM2,STEAP3,TMEM37,SCN2A,FAM155B,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,CSN2,KLHL3,SLC9C1,SLC39A8,ANK2,KCNH5,ATOX1,JPH1,SLC25A28,ABCC2,KCND3,ATP1B1,SFXN1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,SCN5A,SCN8A,ATP6V1E2,GAS6,SLC1A3,SLC12A6,NDFIP2,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,BHLHA15,CACNB2,KCNMB3,SGK1,SLC6A15,NIPAL2,FAM155A,ATP2B1,TRPM4,SLC40A1,KCNQ3,CACNA1E,CALCRL,RASA3,RYR2,STEAP1,PTPRC,CACHD1,KCNK15,GRIN2D,TRPC3,CACNA2D1,ATP2B4,DDIT3,TPT1,ATP1A3 |
| 9.544e-04 | -6.95 | GTGCCAT,MIR-183 | MSigDB lists | GTGCCAT,MIR-183 | 161 | 29 | 17377 | 1707 |
PHLDB2,CELSR3,RHOBTB1,KLHL3,PLEKHA5,PLAG1,BNIP3L,ENAH,ZFPM2,PRKCA,PFN2,NCS1,CTNNA2,HECTD2,DAGLA,PPM1E,ARHGAP21,UNC13B,BACH2,FCHO2,KIAA0355,ZDHHC6,PAM,RAI14,LRP6,ACVR2A,PDE4D,TPM1,MEF2C |
| 9.560e-04 | -6.95 | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | 176 | 31 | 17377 | 1707 |
BCL11B,MAN2B2,SERINC5,ITGB7,GNG12,NBL1,MVK,KLHL3,PLEKHA5,FZD8,ITGA6,LITAF,RNF125,RASA3,ACVR2B,PLEKHA1,FAM174B,ASPH,PLEKHB1,ABLIM1,IQCK,FKBP9,ZNF266,GYPC,KIAA0355,SFMBT1,FHIT,TMEM120B,MLLT3,ZFP36L2,ACSM3 |
| 9.560e-04 | -6.95 | VERHAAK_AML_WITH_NPM1_MUTATED_UP | MSigDB lists | VERHAAK_AML_WITH_NPM1_MUTATED_UP | 176 | 31 | 17377 | 1707 |
PLA2G4A,DMXL2,VNN2,ACSL1,ABCC4,TRIM16,ARHGAP22,LILRB1,HIP1,MAFB,PLS1,COL4A5,PRKAR2B,WARS,QPRT,HOMER3,EPB41L3,CXCL10,TYMP,FGR,CPVL,PRKCD,SLC2A6,ITGB3,BCL6,LAPTM4B,MARCKS,TLR4,SNX10,SMPDL3A,CYP1B1 |
| 9.589e-04 | -6.95 | RPH3AL (rabphilin 3A like (without C2 domains)) | protein interactions | 9501 | 13 | 6 | 17029 | 1718 |
MID2,RAB3B,UNC13B,RAB27B,RIMS2,TCEA3 |
| 9.589e-04 | -6.95 | DBP (D-box binding PAR bZIP transcription factor) | protein interactions | 1628 | 13 | 6 | 17029 | 1718 |
CEBPA,ATF3,HLF,BATF,DDIT3,BATF3 |
| 9.742e-04 | -6.93 | large_cell_carcinoma | COSMIC cancer mutations | large_cell_carcinoma | 862 | 112 | 17385 | 1698 |
EPHA3,ZSWIM5,NEK10,ACVR1,GALNT12,NPM1,CHUK,CEBPA,NTRK3,GRK6,PRKCA,DDR1,RADIL,STK24,SPEG,FBXO32,RPS6KA2,RPS6KL1,MYO3B,ATRNL1,ACVR2A,STEAP3,BEND4,MET,OR2W3,NEB,PRKACB,PDGFRB,DPP10,PHLDB2,FER,TNK2,PRAME,MYLK3,MARK1,PDK1,ACVR1C,EXOC6B,KCNH5,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,C4BPB,DYRK1B,ARMC4,GSN,RANBP2,PRKCB,PLK2,PTK7,ERN1,SEMA3C,MAPK13,BMPR1A,SPRY4,TMEFF2,LIFR,MAST1,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,ROBO2,GALNT13,PKN1,EPHB1,USP30,SYDE2,IGF1R,FRY,ADCK1,PRKCD,GAS2L3,SGK3,KIAA0319,PRKG1,SGK1,SLC6A15,ALPK1,SH3PXD2B,SYK,CAND2,FES,PAK1,FGFR4,BTNL9,LRRIQ1,NUAK2,OBSCN,STRADB,CDC42BPA,ZBBX,GUCY1A2,RERE,MAPKAPK2,TEX15,TRIB3,FGR,ICA1,FAT4,PKN3,AKT3,MAP2K6,NEK11,MYOM2,DHCR7,TLL2 |
| 9.742e-04 | -6.93 | lung-carcinoma-large_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-large_cell_carcinoma | 862 | 112 | 17385 | 1698 |
EPHA3,ZSWIM5,NEK10,ACVR1,GALNT12,NPM1,CHUK,CEBPA,NTRK3,GRK6,PRKCA,DDR1,RADIL,STK24,SPEG,FBXO32,RPS6KA2,RPS6KL1,MYO3B,ATRNL1,ACVR2A,STEAP3,BEND4,MET,OR2W3,NEB,PRKACB,PDGFRB,DPP10,PHLDB2,FER,TNK2,PRAME,MYLK3,MARK1,PDK1,ACVR1C,EXOC6B,KCNH5,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,C4BPB,DYRK1B,ARMC4,GSN,RANBP2,PRKCB,PLK2,PTK7,ERN1,SEMA3C,MAPK13,BMPR1A,SPRY4,TMEFF2,LIFR,MAST1,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,ROBO2,GALNT13,PKN1,EPHB1,USP30,SYDE2,IGF1R,FRY,ADCK1,PRKCD,GAS2L3,SGK3,KIAA0319,PRKG1,SGK1,SLC6A15,ALPK1,SH3PXD2B,SYK,CAND2,FES,PAK1,FGFR4,BTNL9,LRRIQ1,NUAK2,OBSCN,STRADB,CDC42BPA,ZBBX,GUCY1A2,RERE,MAPKAPK2,TEX15,TRIB3,FGR,ICA1,FAT4,PKN3,AKT3,MAP2K6,NEK11,MYOM2,DHCR7,TLL2 |
| 9.755e-04 | -6.93 | GO_ENDOPLASMIC_RETICULUM_PART | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_PART | 1090 | 138 | 17377 | 1707 |
ACSL1,DNAJC3,ITPR2,ABHD4,NOS1AP,FKBP11,TXNDC5,CYP51A1,RTN1,FKBP9,SEC16B,COL19A1,TMED9,RASGRP1,CYP1B1,ATL1,ERGIC1,COL4A3,WLS,TGFA,LRMP,JPH1,NFE2L1,KCND3,INSIG1,RASGRF2,P4HA2,ERN1,TYRO3,ALOX5AP,SEC24D,CYP2J2,ELOVL7,DHCR24,CYP4V2,SCD,SPINK5,PGAP1,RNF180,GALNT1,BNIP1,MSMO1,BCHE,FLRT3,SREBF1,LMAN2,NCEH1,FAR2,MOXD1,COL9A2,CKAP4,HMGCR,FADS1,SLC37A1,RNF170,SLC27A2,MGST3,COL4A4,GPSM1,EDEM3,RYR2,SHISA2,HERPUD1,MFSD2A,SQLE,PTPRN2,PLD1,DHCR7,OSBPL6,CREB3L2,PLA2G4A,ELOVL4,LPCAT2,XYLT1,COL18A1,CANX,SEZ6L2,LPIN3,COL14A1,CYP26A1,CDS1,COL22A1,TLR3,COL25A1,REEP1,ZDHHC6,PROS1,SERPINH1,ALG10B,ANTXR2,COL6A2,TMEM67,EBPL,LRRC8B,TMEM43,CYB5R2,TRAM1L1,C3orf52,ASPH,ATP10D,GJC1,WFS1,PEMT,ALG11,RCN3,P4HA1,CYP2U1,MBOAT2,NR3C2,COL9A3,CLGN,BACE1,UBAC2,CLSTN2,COL4A5,GAS6,GDPD5,COL27A1,SOAT2,SGK1,CERS4,ESD,FKBP14,CES3,AGPAT4,ELOVL3,ARHGAP32,LRAT,ILDR2,GPR37,PLOD2,FMO4,OSBPL5,XBP1,SRD5A3,CERS1,PTGES,ABCG1 |
| 9.771e-04 | -6.93 | V$MYB_Q3 | MSigDB lists | V$MYB_Q3 | 230 | 38 | 17377 | 1707 |
PCSK1N,PPP4R4,TRIM2,GCAT,HEBP1,C4A,CADM2,CANX,NOVA1,ZNF362,SEC16B,FRAS1,LHX6,GAN,TSC22D1,BEND4,TMEM132E,FIGN,ERRFI1,BDNF,ERGIC1,SESN2,ESRRG,PRDM13,FGF12,RASA3,PRICKLE1,SKAP1,CEBPB,KLF12,C1orf21,ALDOA,B3GALT2,KLF5,RPL4,NR3C2,CRISPLD1,DDIT3 |
| 9.771e-04 | -6.93 | V$GATA1_02 | MSigDB lists | V$GATA1_02 | 230 | 38 | 17377 | 1707 |
FGF13,MORC4,CREB5,GRK6,APBA1,ZNF219,SATB1,IKZF2,BMP6,SEMA6A,PCDH7,MCU,RALGPS2,CACNB2,GPR155,LHX6,STC2,FAM107B,PRELID1,HS3ST5,BCL6,ADCY6,TSPAN12,MYT1,TNK2,GPM6A,SLC39A8,ESRRG,JPH1,SATB2,FAM162A,PLEKHB1,SNCA,PELI2,BMP4,SPRY4,LIFR,STON2 |
| 9.771e-04 | -6.93 | V$HNF1_01 | MSigDB lists | V$HNF1_01 | 230 | 38 | 17377 | 1707 |
EPHA3,PLA2G4A,THOC5,CHCHD7,COL4A5,ADAMTS6,STAT5B,ZIC2,FOXP2,EFEMP1,ZNF827,RALGPS2,SOAT2,GAN,EEPD1,ACVR2A,HRK,KLF9,PPP2R2B,ERRFI1,FGFR4,BDNF,TCEA3,PRICKLE1,TNS1,SATB2,CTTNBP2NL,ZFPM2,SGK2,MBNL2,BCL11A,HTR7,SLC39A14,CDH17,ZBTB20,NRP1,SEMA3A,HOXB9 |
| 9.783e-04 | -6.93 | ATP1B4 (ATPase Na+/K+ transporting family member beta 4) | protein interactions | 23439 | 38 | 11 | 17029 | 1718 |
TMEM67,TGFBR3,ITPRIP,CNTNAP3,ENTPD7,PTK7,GAS6,SYNGR3,PGAP1,MYORG,ATP1A3 |
| 9.832e-04 | -6.92 | GuKc | smart domains | SM00072 | 25 | 9 | 9493 | 1056 |
MPP7,MPP1,CACNB2,MPP2,TJP1,DLG2,CACNB4,MAGI2,MAGI3 |
| 9.840e-04 | -6.92 | regulation of cellular component size | biological process | GO:0032535 | 358 | 53 | 17256 | 1658 |
TENM1,FN1,FGF13,BMPR2,TMSB15A,EPS8,PLXNA2,ADD2,NTRK3,SLC12A6,PFN2,RAC3,PPP1R9A,FHOD3,SPIRE1,SCIN,NKX6-1,RND2,SEMA4F,PRKCD,CTTN,IQGAP3,PRR16,SLIT2,NEB,PAK1,FER,VAV3,BDNF,SSH3,EVL,RAB3B,DCC,DSTN,DEPTOR,PREX1,PLS1,BAIAP2,MAP1B,GSN,PLEKHH2,MYADM,WIPF3,NCKAP1L,AKT3,ARHGAP28,PTPRS,TMOD2,SEMA3C,SPART,NRP1,SEMA3A,SHTN1 |
| 9.862e-04 | -6.92 | GO_CALCIUM_ION_BINDING | MSigDB lists | GO_CALCIUM_ION_BINDING | 664 | 90 | 17377 | 1707 |
DOC2A,PLA2G4A,CELSR3,LPCAT2,SYT12,LDLR,SYT14,NRXN1,CANX,DNER,PCLO,HMCN1,NCS1,FSTL5,PCDH7,EPDR1,SCIN,PLS3,NELL2,FKBP9,PROS1,SLIT2,RASGRP1,GCA,KCNIP3,NECAB1,CSN2,EFHC1,F12,ASPH,EML1,SNCA,GSN,ENPP1,CCBE1,BMP1,PAM,RCN3,TC2N,SPOCK3,PSPH,PCDH18,NECAB2,PLSCR4,CELSR1,CLGN,LRP4,MCTP2,CLSTN2,GAS6,HPCAL4,PRRG4,PPP2R3A,PCDHB14,EFEMP1,EHD3,DSG2,TBC1D9,FKBP14,CDH26,PCDH10,TBC1D8B,RAPGEF2,CACNA1E,DCHS1,EFHC2,VLDLR,EDEM3,PRRG1,RYR2,PLS1,C1R,PLCB1,MGMT,HEG1,GALNT3,MMP15,FAT4,PCDHB7,FBN1,THBS4,FAT1,MATN2,CDH17,EGFL7,CDH2,TESC,MMP16,TPT1,TLL2 |
| 9.905e-04 | -6.92 | Glutamatergic synapse | KEGG pathways | hsa04724 | 114 | 23 | 7161 | 730 |
PLA2G4A,DLGAP1,GNG12,GRIK2,HOMER2,SHANK2,ADCY1,SLC1A3,ITPR2,PRKCA,PLCB1,GRK3,HOMER3,GNAI1,GRIK4,PRKCB,GNAO1,GNB4,ADCY6,TRPC1,GRIN2D,PLD1,PRKACB |
| 9.905e-04 | -6.92 | Glutamatergic synapse | KEGG pathways | ko04724 | 114 | 23 | 7161 | 730 |
PLA2G4A,DLGAP1,GNG12,GRIK2,HOMER2,SHANK2,ADCY1,SLC1A3,ITPR2,PRKCA,PLCB1,GRK3,HOMER3,GNAI1,GRIK4,PRKCB,GNAO1,GNB4,ADCY6,TRPC1,GRIN2D,PLD1,PRKACB |
| 9.913e-04 | -6.92 | V$HLF_01 | MSigDB lists | V$HLF_01 | 238 | 39 | 17377 | 1707 |
PRKAA2,MRC2,TTC39B,RBFOX2,PLAG1,CREB5,PFN2,ZFYVE9,ARHGAP44,CHN1,EEF2,PDZD8,BCL6,TSC22D1,PRKG1,KLF9,PDE4D,USP2,MEIS2,CRIM1,ELMOD1,PRICKLE1,CALCRL,ZDHHC14,SLC46A3,MBNL2,PLCB1,HERPUD1,SMAD3,ZNF711,TMEM154,MAP2K6,PELI2,MPP2,TNFSF15,SPRY4,OSBPL6,FOXA1,DDIT3 |
| 9.924e-04 | -6.92 | WW_dom | interpro domains | IPR001202 | 51 | 13 | 18492 | 1811 |
BAG3,PLEKHA5,APBB1,WWTR1,HECW2,YAP1,WWC1,WWC2,TCERG1L,SAV1,MAGI2,MAGI3,NEDD4 |
| 9.945e-04 | -6.91 | GENTILE_UV_RESPONSE_CLUSTER_D8 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D8 | 39 | 11 | 17377 | 1707 |
MN1,INSIG1,NACC2,ZCCHC24,LDLR,SQLE,MARCKS,MET,STK24,HMGCR,HEG1 |
| 9.947e-04 | -6.91 | GO_MESENCHYMAL_CELL_DIFFERENTIATION | MSigDB lists | GO_MESENCHYMAL_CELL_DIFFERENTIATION | 132 | 25 | 17377 | 1707 |
EPB41L5,SEMA6B,MSX1,ACVR1,WNT11,OVOL2,SEMA6A,FGFR1,TGFBR3,SEMA4F,EOMES,HEYL,WWTR1,LRP6,SEMA3C,HGF,BMP4,BMPR1A,NRP1,SEMA3A,SIX2,SNAI2,SEMA6C,HEY1,MEF2C |
| 9.947e-04 | -6.91 | KRAS.LUNG.BREAST_UP.V1_UP | MSigDB lists | KRAS.LUNG.BREAST_UP.V1_UP | 132 | 25 | 17377 | 1707 |
SH2D2A,KIF5A,CLSTN2,KIF5C,TTC22,ADAMTS6,PRDM1,SNAP25,FAM174B,BMP6,CTNNA2,ISG20,CD37,NELL2,KCNK15,GYPC,TERT,ITGA2,SLCO5A1,TNFSF15,GULP1,FAM155B,GFI1,SPRY2,IGFBP3 |
| 9.964e-04 | -6.91 | GSE557_WT_VS_CIITA_KO_DC_DN | MSigDB lists | GSE557_WT_VS_CIITA_KO_DC_DN | 184 | 32 | 17377 | 1707 |
ITGB7,MXI1,DNM3,DYRK3,SORBS1,PRSS16,DUSP8,JDP2,LITAF,TTYH2,RASA3,PLS1,GAS6,C3orf70,SATB1,ASPH,TEX9,PGAP1,COL27A1,QPRT,CYP51A1,ENPP1,ASNS,TMEM237,TECPR2,TUFT1,PACSIN1,HSPA2,ZFP36L2,FOXA1,CKAP4,SMPDL3A |
| 9.964e-04 | -6.91 | GSE7852_TREG_VS_TCONV_LN_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_LN_DN | 184 | 32 | 17377 | 1707 |
CARS,LANCL3,ELOVL7,LDLR,MCTP2,PSD3,IGF2BP2,NTRK3,GABRR2,GPSM2,SATB1,HECTD2,RNF150,TGFBR3,SEMA4F,SLC30A4,EHD3,ITGB3,MAP7,ADCY6,SGK1,MN1,MYO10,RAPGEF4,DNAJC6,ATP1B1,MFSD6,GSN,C1orf21,HS3ST3B1,SLC16A10,AMPD1 |
| 9.964e-04 | -6.91 | GSE45365_NK_CELL_VS_CD8A_DC_DN | MSigDB lists | GSE45365_NK_CELL_VS_CD8A_DC_DN | 184 | 32 | 17377 | 1707 |
LPAR2,SIDT1,GABRB2,LSM11,SEZ6L2,PKN1,RGS7,HECTD2,FSTL5,FBXO32,PPP1R26,KCNN2,KCNAB1,PPFIA2,FAM168A,VGLL4,POU3F3,GPR161,RAB3B,FZD4,GDPD1,TMEM200C,C9orf116,KCNK15,TMEM150B,ENPP6,HOXD13,SPRY4,RNF157,NPHP1,CNTN1,ZNF235 |
| 9.964e-04 | -6.91 | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 184 | 32 | 17377 | 1707 |
CCDC126,LATS2,LCA5,LGALS3,SEC24D,PLEKHA8,UBASH3B,TMEM126A,NUAK2,COBLL1,CR2,CCNG1,NOTUM,PRDM1,KBTBD11,PEAK1,SESN1,ATP10D,IKZF3,TMEM154,MYADM,GRHL1,AKAP7,RBPMS2,SAMD11,ZDHHC23,CERS4,PTPRE,MYT1,RAPGEF5,SMPDL3A,SNAI2 |
| 9.964e-04 | -6.91 | GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_DN | MSigDB lists | GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_DN | 184 | 32 | 17377 | 1707 |
DMXL2,ITGB7,TRIM2,STOX2,RHOQ,NECAB1,RNF144A,KLHL4,MCOLN3,CYP4V2,SPATA13,SELL,AK4,NRXN1,KIF21B,PEAK1,FAM110B,CENPV,TMEM74,RPL34,HLF,RNF217,CDC14B,ERN1,RUNDC3B,MPPED2,NBEA,GRB10,ZBTB20,MARCKS,RNF122,NR3C2 |
| 9.967e-04 | -6.91 | GO_SECRETION_BY_CELL | MSigDB lists | GO_SECRETION_BY_CELL | 467 | 67 | 17377 | 1707 |
DOC2A,SCAMP1,PRSS12,AKAP5,SYT12,VAMP8,GATA3,LILRB1,SYT14,LCP2,NRXN1,CANX,PCLO,CBLN1,PCDH7,SCIN,UNC13B,PPFIA2,ITGB3,RAB26,SCRN1,LIN7A,STEAP3,PROS1,POU2F2,ARL4D,TLR4,RASGRP1,ABCC4,FZD4,WLS,EXOC6B,ACVR2B,RARRES2,TRIM9,ALDOA,HGF,SEPT5,TC2N,PCSK5,TYRO3,SLC6A9,FN1,STXBP5L,SLC1A3,GAS6,APBA1,ARHGAP44,RAB11FIP5,GATA2,CADPS2,STXBP1,SYK,RIMS2,PCSK6,VEGFC,PAK1,QSOX1,PNP,RAPGEF4,PHACTR2,SNAP25,TLR6,ILDR2,RAB31,PTPRN2,SNPH |
| 9.971e-04 | -6.91 | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP | MSigDB lists | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP | 154 | 28 | 17377 | 1707 |
GCA,LATS2,VAV3,CD55,PTPN13,KIF5C,PHACTR2,ST6GALNAC3,CCNG1,PLEKHA1,ITPR2,DOCK5,CD7,IKZF2,NEDD4,ISG20,TRPS1,IKZF3,FRY,EOMES,PLOD2,SERPINI1,TOX,GEM,PACSIN1,TNFSF4,AGL,DUSP1 |
| 1.003e-03 | -6.91 | V$LYF1_01 | MSigDB lists | V$LYF1_01 | 246 | 40 | 17377 | 1707 |
ENO2,IGFBP6,BMPR2,FGF13,VAMP8,TNFRSF19,PRR7,IKZF2,NOVA1,ARHGAP44,SPEG,IGF1R,RALGPS2,PPFIA2,FAM107B,GFRA1,POU3F3,PDGFRB,RNF152,RAX,BDNF,GPM6A,MSTN,SLC39A8,TES,PRDM13,PANK1,PRICKLE1,WNT11,DEXI,ITGA2,BMP1,DLG2,SERPINI1,BMP4,DLX2,NRP1,NKX2-8,NR3C2,MEF2C |
| 1.008e-03 | -6.90 | Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling | WikiPathways | WP3850 | 31 | 10 | 5312 | 569 |
SMAD3,FBXO32,IGF1R,PDK1,MSTN,TNFRSF1A,ACVR2B,PLD1,PPARGC1A,NEB |
| 1.011e-03 | -6.90 | LU_AGING_BRAIN_UP | MSigDB lists | LU_AGING_BRAIN_UP | 254 | 41 | 17377 | 1707 |
CREB3L2,SERINC5,GNG12,ZCCHC24,LRP4,RGS20,CBS,COL4A5,CHSY1,MLC1,DDR1,DDIT4,EFEMP1,PAIP2B,SERPINH1,HSPA2,GATM,CEBPD,GAB2,CYP1B1,FADS1,RIN2,MYO10,PTPN13,RAPGEF4,LITAF,FERMT2,VIM,TMEM47,PALLD,IQCK,GSN,PDLIM3,GPRC5B,PLOD2,WFS1,WWTR1,MAOA,ABCG1,LPP,STOM |
| 1.013e-03 | -6.90 | ion transmembrane transporter activity | molecular function | GO:0015075 | 900 | 116 | 17224 | 1680 |
CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC19A2,SLCO3A1,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,SLC22A17,SLC16A2,SLC22A18,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,ABCC4,LRRC8B,SLC9C1,SLC39A8,SFXN4,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,ABCC2,KCND3,ATP1B1,GJC1,SFXN1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,SCN5A,TMEM63C,SERINC5,SLC6A9,GABRB2,SCN8A,ATP6V1E2,GABRG2,SLC36A4,GAS6,GABRR2,SLC1A3,SLC12A6,SFXN3,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SLC7A11,SCN1B,CACNB2,KCNMB3,SLC16A9,SLC6A15,NIPAL2,SLCO4C1,FAM155A,SLC45A3,ATP2B1,TRPM4,NDUFA4L2,SLC40A1,SLC37A1,KCNQ3,SLC27A2,SLC36A1,CACNA1E,GRID1,RYR2,RASA3,TTYH2,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,SLC7A5,SLCO5A1,GRIN2D,SLC22A15,SLC1A5,TRPC3,SLC16A10,ATP2B4,CACNA2D1,SLC43A1,ATP1A3 |
| 1.017e-03 | -6.89 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 262 | 42 | 17377 | 1707 |
TYRO3,NBL1,SEMA6B,MVK,C1QTNF3,ROBO2,UBASH3B,ST6GAL1,CD276,TNFAIP8L2,GATA3,CUEDC2,ABAT,NRXN1,SPINK5,SEMA6A,CTNNA2,SEMA4F,PRKCD,PRKG1,PROS1,SLIT2,SEMA6C,SNAI2,NOS3,HMGCR,PHLDB2,QSOX1,LRRK2,FEZ1,CALCRL,PRDM1,F12,SMPDL3B,SMAD3,TNFRSF1A,HGF,INPP5F,SEMA3C,NRP1,SEMA3A,LZTS1 |
| 1.019e-03 | -6.89 | GO_CELL_JUNCTION_ASSEMBLY | MSigDB lists | GO_CELL_JUNCTION_ASSEMBLY | 125 | 24 | 17377 | 1707 |
SORBS1,UGT8,FN1,RHOD,GJB2,ANK2,ITGA6,ARL2,PKP2,FERMT2,TNS1,TJP1,WNT11,PRKCA,HEG1,GJC1,EPB41L3,MPP7,MARVELD2,ITGA2,ITGB3,CTTN,TLN2,OCLN |
| 1.020e-03 | -6.89 | GO_NEURONAL_POSTSYNAPTIC_DENSITY | MSigDB lists | GO_NEURONAL_POSTSYNAPTIC_DENSITY | 51 | 13 | 17377 | 1707 |
DLGAP1,EPB41L3,BMPR2,CAP2,DNAJC6,CLSTN2,ADD2,BNIP3,DLG2,P2RY1,CTNNA2,BAIAP2,MAP1B |
| 1.020e-03 | -6.89 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_UP | 51 | 13 | 17377 | 1707 |
UNC5C,PLEKHH2,CELSR3,CSF1,CYP2J2,TMTC4,SEMA3C,NRN1,IL1RAP,C9orf116,PERP,F3,PCSK5 |
| 1.020e-03 | -6.89 | chr4q35 | MSigDB lists | chr4q35 | 28 | 9 | 17377 | 1707 |
STOX2,ACSL1,TLR3,PDLIM3,ENPP6,CCDC110,CYP4V2,FAM149A,WWC2 |
| 1.020e-03 | -6.89 | GO_GLUCOSE_CATABOLIC_PROCESS | MSigDB lists | GO_GLUCOSE_CATABOLIC_PROCESS | 28 | 9 | 17377 | 1707 |
PFKFB4,HK1,GAPDH,ENO2,ENO1,PFKFB2,ALDOC,ALDOA,HK2 |
| 1.020e-03 | -6.89 | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_CLUSTER_DN | 28 | 9 | 17377 | 1707 |
IRS2,TRIM34,SLC7A11,RECK,RNF125,AIG1,ZBTB20,RRAS2,B4GALT6 |
| 1.023e-03 | -6.89 | GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | MSigDB lists | GO_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 1337 | 165 | 17377 | 1707 |
ACSL1,TRIM16,GATA3,LILRB1,ASS1,STAT5B,ITPR2,ABAT,AARS,STK24,F3,FBXO32,TGFBR3,RPS6KA2,AKAP7,TLR4,SLIT2,PRKACB,PDGFRB,NKX2-1,CYP1B1,GDAP1,SESN2,ACVR1C,GJB2,LRRK2,YAP1,PRKAR2B,ABCC2,ACVR2B,PLEKHA1,GNAI1,GSN,ENPP1,ATP7B,GNB4,ERN1,TNFRSF1A,OXTR,TPM1,PPARGC1A,TNFSF4,RRAGD,MEF2C,PRKAA2,GNG12,INPPL1,FN1,ST6GAL1,ATP6V1E2,TNFRSF10C,MLC1,CA2,IGF1R,ZNF354A,EEF2,BCHE,SREBF1,LRP6,ADCY6,BNIP3,CHRM3,NOS3,HMGCR,FGFR4,PAK1,RHOQ,MSTN,VLDLR,EDEM3,CALCRL,RYR2,SDK1,PLCB1,CPEB1,BAIAP2,DAGLA,MAPKAPK2,MMP15,SH3BP4,RAB31,PTPRN2,TRPC3,TESC,SMYD3,EPHA3,PLA2G4A,ID1,SORBS1,IL15,COL18A1,NTRK3,CHUK,ASNS,DAB2IP,PDE4D,PROS1,FZD1,FER,COL6A2,FZD4,PFKFB2,ADCY1,WNT11,PRKCQ,CD40,ASPH,SNCA,IRS2,CXCL10,PRKCB,PTK7,PEMT,EIF4EBP1,ITGA2,PAM,RGS10,GRB10,PSPH,PLSCR4,IPO5,EPS8,SELL,GAS6,BMP6,NKX6-1,RAB11FIP5,HMGCS1,DSG2,STC2,GHR,PRKCD,TFAP2A,KLF9,ERRFI1,GFI1,TNFRSF11A,ATP2B1,DUSP1,PXN,NR4A1,RAPGEF2,LITAF,ILDR2,MGMT,GPLD1,DKK1,CEBPB,ID3,TRIB3,FBN1,GNAO1,ACER2,MAP2K6,XBP1,PCGF2,BMP4,CMPK2,CERS1,TBC1D4,PTGES,FOXA1,ATP2B4,DDIT3,ATP1A3 |
| 1.024e-03 | -6.88 | enzyme activator activity | molecular function | GO:0008047 | 522 | 73 | 17224 | 1680 |
ARHGAP26,FGF13,RASAL2,DOCK1,ARHGAP22,RGS20,FAM13A,TBC1D30,DOCK2,TIAM2,TBC1D19,ADPRHL1,SIPA1L2,DAB2IP,PCOLCE2,RASGRP1,IGFBP3,TBC1D8,LRRK2,ELMOD1,PREX1,WNT11,ATP1B1,TBC1D16,RANBP2,ARHGAP21,NRG3,GPRC5B,BEX3,NCKAP1L,RGS10,DUSP19,ARHGAP28,NRP1,RGS16,ALOX5AP,FN1,STXBP5L,ARHGEF11,TBC1D1,OPHN1,GAS6,RGS7,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,PRKCD,SRGAP1,RALGAPA2,AFAP1L2,SH3PXD2B,ERRFI1,TBC1D9,SPRY2,MOB1B,RIN2,VAV3,ARAP2,TBC1D8B,RAPGEF2,ASAP3,RASA3,AGAP2,ARHGAP32,RACK1,PLCB1,TBC1D2,MMP15,ADGRB3,TBC1D4,MMP16 |
| 1.025e-03 | -6.88 | Rps26 (ribosomal protein S26) | protein interactions | 27139 | 3 | 3 | 17029 | 1718 |
PRICKLE1,PRICKLE2,STXBP5L |
| 1.025e-03 | -6.88 | ZNF83 (zinc finger protein 83) | protein interactions | 55769 | 3 | 3 | 17029 | 1718 |
SMAD3,PAK1,SMAD9 |
| 1.025e-03 | -6.88 | GDF2 (growth differentiation factor 2) | protein interactions | 2658 | 3 | 3 | 17029 | 1718 |
ACVR2A,ACVR2B,BMPR2 |
| 1.026e-03 | -6.88 | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | MSigDB lists | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | 70 | 16 | 17377 | 1707 |
COL6A2,PLXNA2,NLGN4X,DDR1,SMAD3,PLAGL1,RPS6KL1,FAT1,PTK7,CCBE1,BMP1,TNFRSF1A,BNIP3,MET,TSPAN9,FZD1 |
| 1.026e-03 | -6.88 | chr7q21 | MSigDB lists | chr7q21 | 70 | 16 | 17377 | 1707 |
CYP51A1,TECPR1,ASNS,BHLHA15,CLDN12,KIAA1324L,RUNDC3B,SEMA3C,HGF,MAGI2,DYNC1I1,PPP1R9A,STEAP1,CACNA2D1,GNAI1,FZD1 |
| 1.027e-03 | -6.88 | GCM_AQP4 | MSigDB lists | GCM_AQP4 | 45 | 12 | 17377 | 1707 |
RNF141,IL17D,ARHGAP21,GPRC5B,LRP4,PREX1,TTYH2,NDRG2,TMOD2,TMEM47,DNER,FMNL2 |
| 1.027e-03 | -6.88 | GO_ADP_METABOLIC_PROCESS | MSigDB lists | GO_ADP_METABOLIC_PROCESS | 45 | 12 | 17377 | 1707 |
PFKFB4,AK1,GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,OGDHL,HK2,AK4,HK1,ENO1 |
| 1.027e-03 | -6.88 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | 45 | 12 | 17377 | 1707 |
ID1,SMAD9,MYC,KCNG1,SH3BP4,BMP1,MAFB,WNT11,STEAP3,BMP4,TPD52L1,CPEB1 |
| 1.032e-03 | -6.88 | PI3K-Akt signaling pathway | KEGG pathways | hsa04151 | 341 | 53 | 7161 | 730 |
CREB3L2,PRKAA2,COL9A3,GNG12,LPAR2,FN1,FGF13,ITGA6,LAMC3,CHUK,COL4A5,CREB5,PKN1,PRKCA,PPP2R3A,DDIT4,IGF1R,PIK3AP1,MYC,GHR,ITGB3,SGK3,SGK1,PPP2R2B,MET,PCK2,TLR4,COL9A2,SYK,PDGFRB,NOS3,FGFR4,VEGFC,ITGB7,COL6A2,ATF4,COL4A3,NR4A1,COL4A4,FGF12,EFNA3,FGF17,SGK2,FGFR1,PKN3,CSF1,THBS4,EIF4EBP1,AKT3,GNB4,ITGA2,LAMB1,HGF |
| 1.032e-03 | -6.88 | PI3K-Akt signaling pathway | KEGG pathways | ko04151 | 341 | 53 | 7161 | 730 |
CREB3L2,PRKAA2,COL9A3,GNG12,LPAR2,FN1,FGF13,ITGA6,LAMC3,CHUK,COL4A5,CREB5,PKN1,PRKCA,PPP2R3A,DDIT4,IGF1R,PIK3AP1,MYC,GHR,ITGB3,SGK3,SGK1,PPP2R2B,MET,PCK2,TLR4,COL9A2,SYK,PDGFRB,NOS3,FGFR4,VEGFC,ITGB7,COL6A2,ATF4,COL4A3,NR4A1,COL4A4,FGF12,EFNA3,FGF17,SGK2,FGFR1,PKN3,CSF1,THBS4,EIF4EBP1,AKT3,GNB4,ITGA2,LAMB1,HGF |
| 1.033e-03 | -6.88 | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | 192 | 33 | 17377 | 1707 |
CREB3L2,MTG1,ALOX5AP,ZCCHC24,DHCR24,MCTP2,CTBP2,INPP1,IL18R1,TOX,CERS4,ALPK1,NCAM1,SLCO4C1,PTPRE,SYK,CEBPD,PPP1R3D,RHOQ,ARAP2,CRIM1,MCF2L2,MFSD6,ATP10D,HEG1,GALNT3,PTPRC,GSN,INSIG1,NCKAP1L,TNFRSF1A,ATP2B4,STOM |
| 1.033e-03 | -6.88 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | 192 | 33 | 17377 | 1707 |
CREB3L2,GCAT,GATA3,RASL11B,STAT5B,PRKCA,PFN2,AARS,BAG3,GRHL1,PCBP4,TSC22D1,ADCY6,RCAN3,STXBP1,FMNL2,RASGRP1,ERGIC1,EIF4E3,SYNPO2,MYO10,TES,PRDM1,LHPP,TGDS,KCNMB4,PLAGL1,NCAM2,HEYL,RGS10,HK1,NRP1,RRAGD |
| 1.033e-03 | -6.88 | GO_EAR_DEVELOPMENT | MSigDB lists | GO_EAR_DEVELOPMENT | 192 | 33 | 17377 | 1707 |
CELSR1,GABRB2,MCOLN3,OTX1,GATA3,CEBPA,NTRK3,DDR1,PLS3,PDZD7,GATA2,DLX6,TFAP2A,LIN7A,SPRY2,PDGFRB,MSX1,NKX3-2,DCHS1,MAFB,ATOH1,HOXA1,FGFR1,ZIC1,MAPKAPK2,INSIG1,FAT4,PTK7,WDR19,BMP4,NRP1,ATG5,SIX2 |
| 1.033e-03 | -6.88 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_UP | 192 | 33 | 17377 | 1707 |
CXCR5,SERINC5,TNIK,ITGA6,LDLR,MCOLN3,LRRCC1,SELL,KCTD12,ADAMTS6,COL14A1,PIK3AP1,CNKSR3,SLC16A9,NCEH1,NEB,MN1,EIF4E3,GSTM4,NUAK2,AIG1,ATP1B1,NPC2,C3orf70,SESN1,CXCL10,PMEPA1,RGS10,INPP4B,P4HA1,INPP5F,RNF130,RRAGD |
| 1.033e-03 | -6.88 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | 192 | 33 | 17377 | 1707 |
B9D1,VAV3,EIF4E3,SCAMP1,ST14,WLS,GJB2,CAPN5,PDE8A,GSTO1,PRDM1,BATF,ARRDC4,FAM174B,SNX9,SCIN,GABARAPL1,HOPX,ENTPD1,EPCAM,ICA1,PTPRJ,PMEPA1,EIF4EBP1,ALDOC,GNB4,MATN2,RAB31,TSPAN12,MED7,TRPC3,CSRP2,SNAI2 |
| 1.036e-03 | -6.87 | cation transmembrane transporter activity | molecular function | GO:0008324 | 661 | 89 | 17224 | 1680 |
CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,SLC22A18,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,SLC9C1,SLC39A8,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,KCND3,ATP1B1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,TMEM63C,SERINC5,SCN5A,SLC6A9,SCN8A,ATP6V1E2,SLC36A4,GAS6,SLC1A3,SLC12A6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,CACNB2,KCNMB3,SLC6A15,NIPAL2,FAM155A,SLC45A3,ATP2B1,NDUFA4L2,TRPM4,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RASA3,RYR2,TMCO3,GRIK4,KCNK15,SLC2A6,GRIN2D,SLC1A5,TRPC3,CACNA2D1,ATP2B4,ATP1A3 |
| 1.038e-03 | -6.87 | peptidyl-tyrosine dephosphorylation | biological process | GO:0035335 | 99 | 20 | 17256 | 1658 |
SSH3,DUSP8,PTPRD,PTPRU,PTPN13,PTPN6,UBASH3B,DNAJC6,PTPN21,DUSP9,EYA4,PTPRC,PTPRJ,CDC14B,PALD1,DUSP19,PTPRS,PTPRN2,PTPRE,DUSP1 |
| 1.038e-03 | -6.87 | ACACTGG,MIR-199A,MIR-199B | MSigDB lists | ACACTGG,MIR-199A,MIR-199B | 147 | 27 | 17377 | 1707 |
GCNT2,PXN,CELSR1,FZD4,KLHL3,ST6GAL1,ANK2,MGAT4B,NFE2L1,MAFB,DDR1,HMCN1,CCNJ,RANBP2,ARHGAP21,HLF,MAP1A,KLF12,KIAA0355,FLRT3,ACVR2A,GRB10,PDE4D,PPARGC1A,NTNG1,KIF1B,BTRC |
| 1.038e-03 | -6.87 | YEGNASUBRAMANIAN_PROSTATE_CANCER | MSigDB lists | YEGNASUBRAMANIAN_PROSTATE_CANCER | 118 | 23 | 17377 | 1707 |
EPHA3,PRAME,GPM6A,PAGE1,FGF13,CLGN,SLC39A8,SSX1,ARHGEF26,GPR37,MAGEA12,NCAM2,BCHE,PDE10A,MAGEA3,GTF2F2,HPGD,MAGEA6,ETV1,OCLN,CTH,SLC43A1,HRASLS |
| 1.042e-03 | -6.87 | positive regulation of biomineral tissue development | biological process | GO:0070169 | 40 | 11 | 17256 | 1658 |
SMAD3,ENAM,ACVR1,BMPR2,TFAP2A,ACVR2A,BMPR1A,BMP4,ACVR2B,BMP6,MEF2C |
| 1.042e-03 | -6.87 | ventricular septum morphogenesis | biological process | GO:0060412 | 40 | 11 | 17256 | 1658 |
ACVR1,TGFBR3,BMPR2,HEYL,NSD2,WNT11,BMP4,ZFPM2,SAV1,FZD1,HEY1 |
| 1.043e-03 | -6.87 | endothelial cell development | biological process | GO:0001885 | 46 | 12 | 17256 | 1658 |
ID1,MYADM,MARVELD2,RAPGEF2,COL18A1,PTPRS,GSTM3,TJP1,PDE4D,MET,ARHGEF26,HEG1 |
| 1.046e-03 | -6.86 | WINZEN_DEGRADED_VIA_KHSRP | MSigDB lists | WINZEN_DEGRADED_VIA_KHSRP | 97 | 20 | 17377 | 1707 |
TMC7,BDNF,ELOVL4,TGFA,ITGA6,F3,DKK1,CXCL10,TGFBR3,FRY,PMAIP1,CLDN12,TRPC1,SERPINI1,SPRY4,GEM,ERRFI1,SPRY2,PKIA,SMPDL3A |
| 1.046e-03 | -6.86 | KOBAYASHI_EGFR_SIGNALING_24HR_UP | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_UP | 97 | 20 | 17377 | 1707 |
VAV3,MXI1,TRIM2,ACSL1,DEPTOR,ASS1,ABHD4,HEG1,GSN,ID3,BDH2,AHNAK2,BCL6,MAOA,LIMCH1,PROS1,TBC1D9,CPE,CEBPD,CYP1B1 |
| 1.049e-03 | -6.86 | Hemostasis | REACTOME pathways | R-HSA-109582 | 632 | 83 | 10287 | 971 |
PLA2G4A,PDE1B,DOCK1,KIF5A,JCHAIN,GATA3,ITPR2,KIF21B,LCP2,DOCK3,PRKCA,ABHD6,DOCK2,PCDH7,F3,EPCAM,ITGB3,PROS1,RAB27B,RASGRP1,PRKACB,DOCK8,GAB2,SLC3A2,ABCC4,PTPN6,PRKAR2B,PRKCQ,ATP1B1,F12,RARRES2,DOCK5,JAM3,GNAI1,KCNMB4,GYPC,PRKCB,GNB4,ALDOA,ITGA2,HGF,GNG12,FN1,GRB14,ITGA6,SELL,HBE1,P2RY1,GAS6,SELENOP,SLC7A11,GATA2,PDE10A,EHD3,PRKCD,PRKG1,KCNMB3,PRKG2,JAM2,SYK,ATP2B1,NOS3,VEGFC,QSOX1,HBG2,VAV3,RAPGEF4,SDC3,PHACTR2,ZFPM2,GUCY1A2,DAGLA,FGR,DOCK7,PRCP,AKT3,SLC7A5,KIF21A,TRPC3,DOCK6,KIF1B,ATP2B4,DOCK9 |
| 1.052e-03 | -6.86 | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE20366_EX_VIVO_VS_DEC205_CONVERSION_NAIVE_CD4_TCELL_DN | 177 | 31 | 17377 | 1707 |
GPR176,RGS16,LCA5,LANCL3,TUBA1A,PNRC1,WLS,MLF1,MCOLN3,NFIA,RYR2,NRN1,AIG1,ATF3,NOTUM,SFXN3,SEZ6L2,PRKCA,IKZF2,TBC1D30,FKBP11,TRPS1,TEX15,PLAGL1,PIK3AP1,CCDC122,SGK1,CAB39L,KLF9,NRP1,CDH2 |
| 1.052e-03 | -6.86 | GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN | 177 | 31 | 17377 | 1707 |
GPR63,GCA,VNN2,SSH3,DYRK3,TGFA,LITAF,TNS1,NRN1,TNFRSF10C,CREB5,GUCY1A2,EPHB1,TLR6,GALNT14,DENND3,RNF141,KCTD15,SLC7A11,LHX6,CHRDL1,BCL6,TUFT1,SEMA3C,FAR2,TTC39A,TLR4,RAPGEF5,MME,FOXA1,HEY1 |
| 1.052e-03 | -6.86 | GO_REGULATION_OF_CHEMOTAXIS | MSigDB lists | GO_REGULATION_OF_CHEMOTAXIS | 177 | 31 | 17377 | 1707 |
VEGFC,EFNB2,SEMA6B,NBL1,FN1,ROBO2,BMPR2,MPP1,ST6GAL1,PLXNA2,NTRK3,GAS6,RARRES2,SEMA6A,JAM3,FGFR1,F3,SMAD3,CXCL10,SEMA4F,NCKAP1L,THBS4,CSF1,ITGA2,SEMA3C,NRP1,MET,SEMA3A,SLIT2,SEMA6C,PDGFRB |
| 1.061e-03 | -6.85 | ALFANO_MYC_TARGETS | MSigDB lists | ALFANO_MYC_TARGETS | 231 | 38 | 17377 | 1707 |
NBL1,MXI1,CELSR3,ATP8A1,ITGA6,KCTD12,GAS6,RND2,RSL24D1,TACC2,CACNB2,MYC,SMTN,MARCKS,CTH,GLDC,QSOX1,PXN,PNP,MSTN,RAPGEF2,CRIP2,AK4,NPC2,ATP1B1,HERPUD1,MAP1B,PYCR1,GSN,ID3,CCNA1,SVIL,PTPRN2,BMP4,DHCR7,LARP1,MME,STOM |
| 1.062e-03 | -6.85 | FCH_dom | interpro domains | IPR001060 | 23 | 8 | 18492 | 1811 |
FER,PACSIN1,FNBP1L,FCHO2,PSTPIP2,FES,PACSIN3,SRGAP1 |
| 1.066e-03 | -6.84 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 | 368 | 55 | 17377 | 1707 |
TYRO3,RASAL2,ZHX3,MLF1,LRRC49,RADIL,PFN2,ABHD6,NIPSNAP3B,TTC30B,MOK,PPM1E,KIAA1257,DNAH6,REEP1,MORN2,MDH1B,FANK1,DNAH5,KIAA1549,ZFP36L2,PCSK6,C3orf67,DZANK1,TMEM67,EML6,SPATA6,CYTH3,EFHC2,SHANK2,TTC30A,AIG1,EFHC1,ZBBX,EML1,C9orf116,MKX,ARMC4,IQCK,IFT81,IQCH,NACC2,IGIP,ISM1,GBP1,DUSP19,NEK11,FAM149A,CYP2U1,LRRK1,CMPK2,LRRC27,STON2,NPHP1,C8orf48 |
| 1.068e-03 | -6.84 | positive regulation of protein modification process | biological process | GO:0031401 | 1191 | 146 | 17256 | 1658 |
ACSL1,ACVR1,FGF13,GATA3,PRKCA,SNX9,STK24,NOS1AP,GSDME,RAP2A,ITGB3,EPHB6,TLR4,PRKACB,RASGRP1,PDGFRB,TNK2,GCNT2,TGFA,LRRK2,PRKAR2B,ACVR2B,ROR1,INHBC,GPRC5B,NCKAP1L,ERN1,TNFRSF1A,DIRAS1,NRP1,PPARGC1A,MAGI2,CACUL1,PRKAA2,TYRO3,FBXO4,SLK,JDP2,SORBS3,TNFRSF10C,PFN2,TNFRSF19,RNF180,IGF1R,SREBF1,ADCY6,INAVA,HMGCR,PAK1,FGFR4,MSTN,VLDLR,DUSP9,WWC1,STRADB,PDE8A,ARRDC4,PLCB1,MAPKAPK2,PELI2,THBS4,CSF1,INHBE,CDH2,SEMA3A,SMYD3,EPHA3,PRKN,AVPI1,NEK10,IL15,NTRK3,LCP2,TNKS1BP1,DDR1,PIBF1,PPP1R9A,TLR3,CDC14B,BCL6,ACVR2A,DAB2IP,MET,HSPA2,IGFBP3,ALG10B,FZD1,FZD4,NOP53,ADCY1,WNT11,RARRES2,CD40,FGFR1,SNCA,NRG3,APELA,WFS1,DUSP19,MAP3K21,TNFSF15,HGF,BMPR1A,MAPK10,MID1,CNTN1,TENM1,TNIK,NECAB2,EDA2R,BMPR2,PAK5,FZD8,LRP4,P2RY1,GAS6,PKN1,NDFIP2,EPHB1,TPD52L1,BMP6,PRKCD,RASD2,GHR,AFAP1L2,IQGAP3,TNFRSF11A,SYK,SPRY2,PARP9,VEGFC,RAPGEF2,PRICKLE1,GAREM1,RACK1,TLR6,DKK1,GPR37,PTPRC,TRIB3,DOCK7,MAP2K6,LRRK1,BMP4,MAP3K20,ATP2B4 |
| 1.070e-03 | -6.84 | HOMER1 (homer scaffold protein 1) | protein interactions | 9456 | 50 | 13 | 17029 | 1718 |
EFNB2,DBN1,PRKN,DNM3,FAT1,ABI3,HOMER2,RYR2,TRPC1,KIF5C,AGAP2,TPM1,HOMER3 |
| 1.071e-03 | -6.84 | positive regulation of macromolecule metabolic process | biological process | GO:0010604 | 3113 | 346 | 17256 | 1658 |
THOC5,ACVR1,LGR4,DNAJC3,LDLR,GATA3,NPM1,CTBP2,STAT5B,CEBPA,PRKCA,SNX9,EYA4,STK24,NOS1AP,TRPS1,SKI,PMAIP1,FAM168A,RAP2A,POU3F3,NKX2-1,MEIS2,SMAD9,ACVR1C,NR6A1,TGFA,LRRK2,NFIA,MEF2B,PRKAR2B,ACVR2B,F12,AHRR,HLF,NCKAP1L,CCBE1,PLK2,BBC3,INPP5F,DIRAS1,NRP1,MEF2C,ITGA6,SLK,TNFRSF10C,TNFRSF19,MECOM,APLF,MYC,PRELID1,SREBF1,GRIP1,GLIS1,PRR16,RIMS2,HMGCR,RPL26,STAT4,VLDLR,FHL2,PACSIN3,NSD2,HIP1,SMARCD3,TAF4B,ARRDC4,PLCB1,FAM162A,PELI2,THBS4,INHBE,HOXD13,CDH2,SMYD3,EPHA3,ZNF516,RNF144A,OTX1,CHUK,LCP2,DDR1,TLR3,DACT1,DAB2IP,PERP,FZD1,ADM2,FZD4,SOX21,ADCY1,ATF3,SATB2,PRKCQ,WNT11,PXYLP1,PYGO1,ATOH1,ASPH,FGFR1,SNCA,IRS2,ZNF711,CXCL10,IKZF3,BEX3,WFS1,APELA,PEMT,WWTR1,MAP3K21,TNFSF15,KLF5,BMPR1A,DBP,MAPK10,HOXB9,MID1,EDA2R,CKAP2,PLAG1,CD276,FZD8,GAS6,P2RY1,CREB5,PKN1,EPHB1,ZNF219,NDFIP2,TPD52L1,NEDD4,GSAP,KDM7A,BHLHA15,GHR,YBX3,MYO6,SMAD6,SPRY2,ZFP36L2,MED12L,PARP9,VEGFC,SLC40A1,RAPGEF2,GAREM1,RACK1,SKAP1,HOXA1,ZIC1,GPLD1,CEBPB,PTPRC,TRIB3,NSD1,TERT,XBP1,BMP4,LRRK1,SHOX2,DDIT3,ATP2B4,FOXA1,LARP1,BTRC,ACSL1,FGF13,TRIM16,LILRB1,IKZF2,GSDME,F3,ARHGEF10L,EPCAM,EOMES,SEC16B,GRHL1,ITGB3,PCOLCE2,EPHB6,ENO1,FANK1,TLR4,ETV1,PDGFRB,RASGRP1,PRKACB,LAMP3,TNK2,ATF4,GCNT2,SESN2,COL4A3,ANK2,NFE2L1,YAP1,ROR1,BATF,DYRK1B,INHBC,GSN,GPRC5B,INSIG1,ERN1,TNFRSF1A,NCOA7,DLX2,PPARGC1A,TNFSF4,MAGI2,CACUL1,MLLT3,BCL11B,PRKAA2,TYRO3,LONRF1,RUNX2,FN1,BVES,JDP2,FBXO4,SORBS3,ZIC2,PFN2,RNF180,ZBTB38,EEF2,IGF1R,GATA2,EBF4,LRP6,ADCY6,INAVA,BARX1,CAND2,CEBPD,PAK1,FGFR4,RAX,ATP5IF1,RHOQ,MSTN,EFNA3,WWC1,MAFB,STRADB,DUSP9,PDE8A,PRDM1,HERPUD1,MAPKAPK2,PLAGL1,CSF1,HEYL,NKX2-8,SEMA3A,TESC,SIX2,CREB3L2,PRKN,SORBS1,ID1,AVPI1,NEK10,IL15,HECW2,NTRK3,LPIN3,TNKS1BP1,PIBF1,PPP1R9A,CDC14B,BCL6,ACVR2A,POU2F2,MET,HSPA2,GLI1,IGFBP3,ALG10B,NOP53,RNF125,VIM,RARRES2,CD40,C4BPB,WARS,CAMK2N1,SMAD3,NRG3,RNF217,ITGA2,DUSP19,SOHLH2,HGF,HEY1,CNTN1,TENM1,TNIK,NECAB2,BMPR2,ARHGEF11,PAK5,REL,APBB1,LRP4,SLX1B,OVOL2,BMP6,NKX6-1,PRKCD,RASD2,GTF2F2,TFAP2A,ACTA2,AFAP1L2,SH3PXD2B,IQGAP3,TNFRSF11A,SYK,MICAL2,MSX1,KDM5B,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,PRICKLE1,MARS,ZFPM2,TLR6,MGMT,DKK1,RERE,EBF1,GPR37,DOCK7,EDA,ACER2,MAP2K6,MYRF,PAX9,MAP3K20,KIF1B |
| 1.076e-03 | -6.83 | MAPK signaling pathway | KEGG pathways | ko04010 | 255 | 42 | 7161 | 730 |
PLA2G4A,GNG12,CACNG3,DUSP8,FGF13,CHUK,PRKCA,CACNB4,RAC3,MECOM,RPS6KA2,CACNB2,MYC,RRAS2,HSPA2,PRKACB,RASGRP1,PDGFRB,DUSP1,PAK1,FGFR4,BDNF,ATF4,CACNA1E,NR4A1,RAPGEF2,FGF12,DUSP9,FGF17,FGFR1,MAPKAPK2,PRKCB,MAP2K6,AKT3,RASGRF2,TNFRSF1A,MAPK13,MAPK10,MAP3K20,CACNA2D1,DDIT3,MEF2C |
| 1.076e-03 | -6.83 | MAPK signaling pathway | KEGG pathways | hsa04010 | 255 | 42 | 7161 | 730 |
PLA2G4A,GNG12,CACNG3,FGF13,DUSP8,CHUK,PRKCA,CACNB4,RAC3,MECOM,RPS6KA2,MYC,CACNB2,RRAS2,HSPA2,PDGFRB,PRKACB,RASGRP1,DUSP1,PAK1,FGFR4,BDNF,ATF4,NR4A1,RAPGEF2,CACNA1E,FGF12,DUSP9,FGF17,FGFR1,MAPKAPK2,PRKCB,MAP2K6,RASGRF2,AKT3,TNFRSF1A,MAPK13,MAPK10,MAP3K20,CACNA2D1,DDIT3,MEF2C |
| 1.082e-03 | -6.83 | calcium ion transmembrane transporter activity | molecular function | GO:0015085 | 141 | 26 | 17224 | 1680 |
TRPM4,GPM6A,CACNG3,SLC3A2,CACNA1E,JPH1,MCOLN3,RYR2,RASA3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,CACNB2,TRPC1,GRIN2D,TMEM37,FAM155B,TRPC3,FAM155A,CACNA2D1,ATP2B1,ATP2B4,DENND5B |
| 1.083e-03 | -6.83 | PLC beta mediated events | REACTOME pathways | R-HSA-112043 | 47 | 12 | 10287 | 971 |
PLA2G4A,PDE1B,GNAO1,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PRKCA,PLCB1,PRKACB,GNAI1 |
| 1.083e-03 | -6.83 | Collagen chain trimerization | REACTOME pathways | R-HSA-8948216 | 47 | 12 | 10287 | 971 |
COL22A1,COL9A3,COL6A2,COL4A3,COL25A1,COL4A4,COL18A1,COL19A1,COL4A5,COL14A1,COL9A2,COL27A1 |
| 1.084e-03 | -6.83 | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | MSigDB lists | REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE | 23 | 8 | 17377 | 1707 |
KCNMB4,PDE1B,PDE10A,KCNMB3,PRKG1,PRKG2,GUCY1A2,NOS3 |
| 1.084e-03 | -6.83 | CLIMENT_BREAST_CANCER_COPY_NUMBER_UP | MSigDB lists | CLIMENT_BREAST_CANCER_COPY_NUMBER_UP | 23 | 8 | 17377 | 1707 |
PAK1,CTTN,KCNQ3,ESRRG,MYC,FGFR1,PREX1,BCL6 |
| 1.084e-03 | -6.83 | OSADA_ASCL1_TARGETS_DN | MSigDB lists | OSADA_ASCL1_TARGETS_DN | 23 | 8 | 17377 | 1707 |
IGFBP6,CRIM1,SEMA3C,KLF5,FGFR1,DUSP1,DKK1,CYP1B1 |
| 1.087e-03 | -6.82 | BMP signaling pathway involved in heart development | biological process | GO:0061312 | 6 | 4 | 17256 | 1658 |
MSX1,BMPR1A,ACVR1,BMP4 |
| 1.087e-03 | -6.82 | cellular lactam metabolic process | biological process | GO:0072338 | 6 | 4 | 17256 | 1658 |
STAT5B,ABCC2,MME,GHR |
| 1.087e-03 | -6.82 | positive regulation of alkaline phosphatase activity | biological process | GO:0010694 | 6 | 4 | 17256 | 1658 |
SMAD3,ITGA2,MEF2C,GPLD1 |
| 1.087e-03 | -6.82 | Purkinje myocyte to ventricular cardiac muscle cell communication | biological process | GO:0086068 | 6 | 4 | 17256 | 1658 |
TRPM4,RYR2,SCN5A,SCN1B |
| 1.088e-03 | -6.82 | cellular component organization or biogenesis | biological process | GO:0071840 | 5595 | 594 | 17256 | 1658 |
ARHGAP26,DOC2A,AASS,RECK,TUBE1,NPM1,CEBPA,CADM2,NHP2,BCAN,SNX9,EYA4,SKI,TGFBR3,IKZF5,PMAIP1,DNAH6,RAP2A,TMED9,COG3,NKX2-1,SMIM20,DCC,CAP2,DSTN,TGFA,GJB2,LRRK2,NFIA,FEZ1,PRKAR2B,KCND3,WIPF3,MAP9,ALDOA,ARHGAP28,BBC3,TMOD2,ERCC5,TPM1,DNHD1,VASH2,MEF2C,ITGA6,SLK,TJP1,GPSM2,BBS9,FOXG1,TTC30B,GRPEL2,CHN1,SYCP2,RSL24D1,BNIP1,FRY,CACNB2,FLRT3,LMAN2,TOX,CADPS2,LOXL4,NCAM1,FIGN,JAM2,STXBP1,GFRA1,FMNL2,RPS23,LRP12,ZNF385A,HMGCR,BDNF,SPATA6,ARID5B,HIP1,SMARCD3,PLS1,SNAP25,ARRDC4,TAF4B,CLN5,TEX15,SH3GL2,RPL28,ADAMTS3,CDH17,CLMN,LAPTM4B,CDH2,SHTN1,MTG1,TFCP2L1,DNM3,TMSB15A,MYO1B,PKP2,ADD2,NRXN1,EPB41L3,GPRIN1,COL25A1,RTKN2,RPL26L1,ZNF365,DNAH5,SNX10,PERP,KCNB2,FZD1,SSH3,MYLK3,GAPDH,COL6A2,FZD4,NPM3,ADCY1,WNT11,RAB38,DSP,GABARAPL1,GJC1,IRS2,ARHGAP21,WWTR1,LAMB1,PAM,P4HA1,RAB30,FARP1,C1QTNF3,ROBO2,BIK,GAS6,SLC12A6,PKN1,EPHB1,KCNC4,COL27A1,NEO1,LRRN1,BHLHA15,GAS2L3,NPTXR,FES,TRPM4,PDLIM7,B9D1,CLYBL,RAPGEF2,ATP11A,HEG1,NSD1,RPL12,PCDHB7,AKT3,GNAO1,NEK11,JHY,FOXA1,PHC1,TLL2,CACNG3,FGF13,TRIM16,SYT12,HDGFL3,SYT14,PLS3,RND2,SEC16B,HPS1,MARVELD2,ITGB3,TBC1D32,LIN7A,COL19A1,TLN2,ETV1,NEB,DBN1,ITGB7,MARK1,COL4A3,ABCC4,ANK2,PLEKHA1,TSKU,TCF7L1,MAP2,TNFRSF1A,AHNAK2,PIK3C2B,TC2N,CHMP4C,PRKAA2,KCNV1,TYRO3,SORBS3,PFN2,MLC1,DOK5,SPIRE1,FHOD3,NUMBL,KIAA1958,SEMA4F,IGF1R,ABCA5,GAN,LRP6,BNIP3,PAK1,DPYSL5,UNC5C,EFNA3,SPATA13,STRADB,OBSCN,SLITRK5,SDK1,BAIAP2,NAP1L5,ATPAF2,SEMA3A,SFN,PRKN,ID1,DOCK1,LPCAT2,RBFOX2,NTRK3,RADIL,TNKS1BP1,PCLO,PPP1R9A,SEMA6A,CTNNA2,TACC2,BCL6,CLVS2,SNAI2,RPS13,CTH,INTU,EVL,TMEM67,TUBA1A,TDRD3,NOP53,PRDM13,THSD4,VIM,JAM3,SMAD3,RANBP2,IFT81,NRG3,GBP1,PTK7,KCNG1,ITGA2,PTPRS,HGF,SEPT5,CTNND2,RETREG1,CNTN1,TENM1,COL9A3,KIZ,DYRK3,BMPR2,PAK5,APBB1,HBE1,USP30,ARHGAP44,TECPR1,MAP1A,SGK1,SH3PXD2B,MICAL2,NUAK2,FERMT2,PALLD,MAP10,DKK1,DOCK7,TMEM237,FAT4,L3MBTL4,FBN1,MYRF,RPL4,TBC1D4,ATP8A1,LDLR,VAMP8,GATA3,ENAH,PRKCA,RAC3,DACH2,STK24,TRPS1,TYMP,NDUFB8,KCNS3,SP140,PACSIN1,PLTP,GDAP1,ACVR1C,LRMP,DNAJC6,DEPTOR,BNIP3L,EFHC1,TNS1,AGO4,ARHGEF26,NCKAP1L,PLK2,BMP1,SEMA3C,SPART,UNC5B,NRP1,EFNB2,LRFN5,INPPL1,ALOX5AP,TBC1D1,PTPRD,DHCR24,OPHN1,MRPL22,SLC1A3,APBA1,DYNC1I1,CHD5,RPL13A,MECOM,MCOLN2,ABLIM1,NAV1,CNTN4,PDZD7,MYC,PRELID1,PRKG1,GRIP1,PRR16,MAST4,COL9A2,BOD1,EPB41L5,RPL26,DISC1,PLEKHA8,COL4A4,VLDLR,PACSIN3,TTC30A,NSD2,PEX5L,CDC42BPA,MMP15,PLEKHH2,VPS37D,CECR2,THBS4,WDR19,MATN2,DYNC2LI1,MPP2,SFMBT1,IQSEC2,SMYD3,EPHA3,NBL1,AMOTL1,TCTN2,RHOD,ST14,GPR65,PLXNA2,MSR1,KCTD12,DDR1,COL14A1,CCDC120,NAP1L3,DAB2IP,MARCKS,SERPINH1,GAB2,TMEM43,SHANK2,PREX1,NLGN4X,PRKCQ,CBY1,SATB2,ATOH1,PYGO1,ATP1B1,ATP10D,PATJ,SNCA,ISG20,TDO2,PRKCB,ASIC1,CCNA1,GRB10,KLF5,ATG5,STON2,COBL,MID1,KCTD1,HACE1,RPS20,WASF3,PLSCR4,ATP9A,EPS8,KIF5C,ARL2,GDPD5,NEDD4,HOPX,RASSF8,KDM7A,LRRC55,SOAT2,AFF2,FIG4,DYNC2H1,SEPT3,SPRY2,VAV3,SYNPO2,PXN,RPL21,ZDHHC15,TERT,PCGF2,SVIL,MYOM2,OCLN,DDIT3,B4GALT7,ATP1A3,MPZL3,UGT8,KIF5A,DNER,CACNB4,QPRT,ARHGEF10L,TUBB4A,LRRC6,GRHL1,ABI3BP,POF1B,CTTN,IL1RAP,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,ATL1,GPM6A,SESN2,SKAP2,YAP1,EML1,GSN,NCAM2,PPARGC1A,MAGI2,FRMD5,BCL11B,FN1,BVES,SEC24D,RHOBTB1,ATP6V1E2,LAMC3,SATB1,SPINK5,PHGDH,ADGRG6,DDIT4,PCDHB14,ZNF354A,RPS11,INAVA,LIMCH1,CAND2,NOS3,SNX7,CDH26,ATP5IF1,RHOQ,SLITRK2,PARD3B,ADGRB3,FCHO2,FAT1,HK2,RAB31,NKX2-8,FNBP1L,DMXL2,SORBS1,CELSR3,PSTPIP2,COBLL1,COL18A1,TDRKH,PIBF1,DOCK2,SCIN,KCTD15,SETDB2,PDZD8,UNC13B,ERO1B,CDC14B,REEP1,MAP7,GULP1,MET,TMEM120B,HSPA2,NTNG1,SEMA6C,SP140L,GCA,PHLDB2,FER,PTPN6,SYNJ2BP,AMIGO1,CD40,CENPV,ARMC4,KPNA3,TRIM34,DISP1,MAST1,TNIK,CLGN,ARHGEF11,LRP4,CMTM8,COL4A5,SLX1B,RPL34,MCU,NKX6-1,FSD1,SCN1B,PRKCD,EHD3,DSG2,KIAA0319,IQGAP3,TESPA1,RAB3B,MSX1,KDM5B,SYBU,MEI1,PEAK1,RERE,MAP1B,MYADM,RND3,MPP7,NACC2,CTSV,RPS12,GEM,MMP16,NPHP1,MAP3K20,ABCG1,STOM |
| 1.092e-03 | -6.82 | V$MEF2_02 | MSigDB lists | V$MEF2_02 | 208 | 35 | 17377 | 1707 |
TYRO3,ARHGAP26,CACNG3,RHOBTB1,GABRB2,NDRG2,PPP2R3A,ZNF362,NELL2,RASD2,HS3ST5,TSC22D1,NBEA,PPP1R3D,ARAP2,USP2,NR4A1,ESRRG,TCEA3,FGF12,ATF3,IFT81,IKZF3,KPNA3,PMEPA1,GNB4,HPGD,DLG2,DIRAS1,MYOM2,PPARGC1A,MLLT3,AMPD1,CNTN1,MEF2C |
| 1.094e-03 | -6.82 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_UP | 185 | 32 | 17377 | 1707 |
RUNX2,LGALS3,JDP2,TNFSF13B,NEDD4,PPP2R3A,SCIN,PLS3,ASNS,SOAT2,AKAP7,MGAT1,MARVELD2,DSG2,GSTM3,MARCKS,MED12L,RNF152,SUSD3,SKAP2,MYO10,SH2D2A,PRDM1,SMPDL3B,CEBPB,SUGT1,ENPP1,RNF217,PMEPA1,CLDN12,GEM,SLC16A10 |
| 1.094e-03 | -6.82 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP | 185 | 32 | 17377 | 1707 |
ARAP2,LANCL3,TMEM43,ATOX1,TNFSF13B,FHL2,NRN1,TNS1,CTTNBP2NL,NPC2,MGAT5B,CDC42BPA,KIAA1217,COL14A1,MGMT,GABARAPL1,RTN1,RGS17,AK1,KCNMB4,ZBTB38,CNKSR3,CACNB2,PPFIBP1,GNB4,PLK2,EHD3,TSPAN13,VGLL4,PTGES,PARP9,STOM |
| 1.094e-03 | -6.82 | peptidyl-tyrosine modification | biological process | GO:0018212 | 189 | 32 | 17256 | 1658 |
EPHA3,TYRO3,FGFR4,FER,TNK2,BTC,DYRK3,IL15,PTPN6,STAT5B,NTRK3,ROR1,FGF17,EPHB1,PEAK1,PIBF1,FRK,DDR1,FGFR1,EFEMP1,DYRK1B,FGR,IGF1R,MAP2K6,PRKCD,GHR,ABI3,HGF,MET,SYK,FES,PDGFRB |
| 1.097e-03 | -6.81 | GO_SECRETORY_GRANULE_MEMBRANE | MSigDB lists | GO_SECRETORY_GRANULE_MEMBRANE | 77 | 17 | 17377 | 1707 |
ABCC4,SCAMP1,ATP8A1,VAMP8,PHACTR2,PCDH7,SNCA,RND2,ICA1,ITGB3,PAM,RAB26,PTPRN2,RAB27B,MYRIP,CPE,LAMP3 |
| 1.098e-03 | -6.81 | MODULE_378 | MSigDB lists | MODULE_378 | 385 | 57 | 17377 | 1707 |
MOCOS,SV2B,ACVR1,ACSL1,FN1,AASS,SLC25A27,BEGAIN,PRDM8,HBE1,SCD,MAPK4,ISYNA1,IL18R1,CBLN1,BAG3,EPHB6,PDE4D,IPCEF1,TBC1D9,FAR2,LRP3,MED12L,SP140L,KDM5B,TBC1D8B,KLHL4,HOMER2,WDR25,SDC3,OBSCN,AGAP2,PRDM1,AMIGO1,TMEM47,SAV1,FGFR1,RERE,SMAD3,DEXI,SPNS1,GSN,CXCL10,CCBE1,CSF1,MAP2K6,WDR19,ABI3,NCOA7,PLEKHG1,DYNC2LI1,NXPH4,GEM,LARP1,PKIA,SLC43A1,RRAGD |
| 1.101e-03 | -6.81 | gated channel activity | molecular function | GO:0022836 | 338 | 51 | 17224 | 1680 |
KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,KCNIP3,KCNQ3,KCNH5,CACNA1E,JPH1,GRID1,CHRNA6,TTYH2,RASA3,RYR2,KCND3,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,CACNA2D1 |
| 1.105e-03 | -6.81 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_DN | 155 | 28 | 17377 | 1707 |
PLA2G4A,VEGFC,SLC3A2,ALDH2,IL32,ENO2,CAP2,ARHGAP22,EPS8,FHL2,ATP1B1,PFN2,BMP6,GLCE,MECOM,DKK1,SMAD3,EFEMP1,PLOD2,AHNAK2,RGS10,ACTA2,FBXL2,TPM1,PLTP,CDH2,PRKACB,PKIA |
| 1.107e-03 | -6.81 | SIPA1L1 (signal induced proliferation associated 1 like 1) | protein interactions | 26037 | 95 | 20 | 17029 | 1718 |
CGN,LATS2,PHLDB2,RASAL2,PTPN13,PLEKHA5,CBY1,LPIN3,NRXN1,FAM110B,DYRK1B,NAV1,RALGPS2,MAP3K21,SH3BP4,TANC2,OSBPL6,SFN,LARP1,GAB2 |
| 1.109e-03 | -6.80 | GSE10325_CD4_TCELL_VS_BCELL_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_DN | 170 | 30 | 17377 | 1707 |
CXCR5,BCL7A,VAV3,RHOQ,SKAP2,PTPN6,SYBU,LRMP,SETBP1,CR2,CD40,SEL1L3,DENND3,ATP10D,BCL11A,RNF141,ENTPD1,KMO,PRKCB,EHD3,SLC2A6,OPN3,TSPAN13,MARCKS,SP140,TBC1D9,RRAS2,SYK,RAB30,MEF2C |
| 1.109e-03 | -6.80 | GO_CELL_CELL_CONTACT_ZONE | MSigDB lists | GO_CELL_CELL_CONTACT_ZONE | 64 | 15 | 17377 | 1707 |
PAK1,SCN5A,FGF13,SCN1B,TMEM65,ANK2,DSG2,PKP2,TJP1,ATP1B1,SCN2A,DSP,CDH2,JAM3,GJC1 |
| 1.109e-03 | -6.80 | SESTO_RESPONSE_TO_UV_C7 | MSigDB lists | SESTO_RESPONSE_TO_UV_C7 | 64 | 15 | 17377 | 1707 |
PLA2G4A,GSN,ACSL1,ASNS,PRCP,ITGA6,XBP1,PAM,ASS1,PCK2,SLC1A5,ESD,AARS,CKAP4,CEBPD |
| 1.113e-03 | -6.80 | neutral amino acid transmembrane transporter activity | molecular function | GO:0015175 | 34 | 10 | 17224 | 1680 |
SERINC5,SLC3A2,SLC6A9,SLC7A11,SLC36A1,SERINC2,SLC7A5,SLC36A4,SLC1A5,SLC43A1 |
| 1.117e-03 | -6.80 | TYRKINASE | prints domains | PR00109 | 98 | 20 | 4652 | 458 |
EPHA3,FGFR4,TYRO3,FER,TNK2,NTRK3,ROR1,EPHB1,DDR1,FRK,FGFR1,FGR,IGF1R,PTK7,MAP3K21,EPHB6,MET,MAP3K20,SYK,FES |
| 1.117e-03 | -6.80 | pyridine-containing compound biosynthetic process | biological process | GO:0072525 | 72 | 16 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,PFKFB2,OGDHL,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1,PARP9 |
| 1.131e-03 | -6.78 | GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_DN | MSigDB lists | GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_DN | 193 | 33 | 17377 | 1707 |
AVPI1,HEBP1,ABHD4,PFN2,HECTD2,PIK3AP1,GPR155,PRKCD,SGK3,RCAN3,ERRFI1,PLTP,SNX10,TNFRSF11A,RWDD2A,RIN2,NR4A1,ARID5B,PREX1,SPATA13,PRDM1,GSN,PTPRJ,SLC2A6,OSBPL5,CDH17,LRRK1,RNF122,TBC1D4,MID1,TESC,BTRC,DIRC2 |
| 1.131e-03 | -6.78 | GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN | 193 | 33 | 17377 | 1707 |
DMXL2,ARHGAP26,ACSL1,FLVCR2,LGALS3,LILRB1,KCTD12,CTBP2,ARHGEF10L,RTN1,CPVL,MGAT1,PRKCD,BCL6,MARCKS,PTPRE,SNX10,SYK,CKAP4,CEBPD,GAB2,RIN2,PPP1R3D,VNN2,GCA,GAPDH,RHOQ,NPC2,TBC1D2,CEBPB,FGR,PLAGL1,RNF130 |
| 1.131e-03 | -6.78 | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 193 | 33 | 17377 | 1707 |
LONRF1,RIN2,ERGIC1,CELSR1,PNP,TMEM65,RECK,CYTH3,CYP4V2,SPATA13,KIF5C,COBLL1,PHACTR2,TMEM170B,SAV1,SESN1,ATP10D,GPLD1,HOPX,ARHGAP21,PTPRJ,GRHL1,AKAP7,GPR160,CNKSR3,XBP1,ATRNL1,DAB2IP,KLF9,GEM,RAPGEF5,SNAI2,SMPDL3A |
| 1.136e-03 | -6.78 | MODULE_176 | MSigDB lists | MODULE_176 | 224 | 37 | 17377 | 1707 |
WASF3,UGT8,EHHADH,PTPRD,CYP2J2,ST6GAL1,NTRK3,EPHB1,RGS7,MLC1,NOVA1,CBLN1,GAS1,NEO1,F3,RPS6KA2,GATA2,SMTN,GSTM3,HRK,POU2F2,GATM,CYP1B1,TGFA,FHL2,PRKCQ,C1R,ROR1,RND3,GBP1,CDH17,HPGD,PTPRS,CDH2,SFN,MEF2C,ACSM3 |
| 1.137e-03 | -6.78 | cation transmembrane transport | biological process | GO:0098655 | 602 | 81 | 17256 | 1658 |
CACNG3,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC9A7,NCS1,KCNAB1,KCNN2,KCNS3,TRPC1,CNNM2,SLC2A12,STEAP3,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,SLC9C1,SLC39A8,KCNH5,ATOX1,CHRNA6,SLC25A28,KCND3,ATP1B1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,SCN5A,SCN8A,ATP6V1E2,SLC36A4,GAS6,SLC1A3,SLC12A6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,BHLHA15,CACNB2,KCNMB3,NIPAL2,FAM155A,ATP2B1,NDUFA4L2,TRPM4,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RASA3,RYR2,STEAP1,PTPRC,TMCO3,KCNK15,SLC2A6,GRIN2D,SLC1A5,TRPC3,CACNA2D1,ATP2B4,DDIT3,ATP1A3 |
| 1.137e-03 | -6.78 | Nitric oxide stimulates guanylate cyclase | REACTOME pathways | R-HSA-392154 | 24 | 8 | 10287 | 971 |
KCNMB4,PDE1B,PDE10A,KCNMB3,PRKG1,PRKG2,GUCY1A2,NOS3 |
| 1.137e-03 | -6.78 | Signaling by BMP | REACTOME pathways | R-HSA-201451 | 24 | 8 | 10287 | 971 |
SMAD9,BMPR2,CHRDL1,ACVR2A,BMPR1A,ACVR2B,SMAD6,SKI |
| 1.139e-03 | -6.78 | CGN (cingulin) | protein interactions | 57530 | 102 | 21 | 17029 | 1718 |
DBN1,LATS2,PHLDB2,RASAL2,TBC1D1,PTPN13,TJP1,CBY1,LPIN3,PPP1R9A,NAV1,RALGPS2,MAP3K21,ACTA2,DAB2IP,TANC2,KIF1B,OSBPL6,SFN,LARP1,GAB2 |
| 1.148e-03 | -6.77 | telencephalon development | biological process | GO:0021537 | 237 | 38 | 17256 | 1658 |
BCL11B,SCN5A,GNG12,ROBO2,FGF13,BCAN,FOXG1,SKI,FOXP2,NUMBL,EOMES,TACC2,LHX6,LRP6,BNIP3,DAB2IP,SLIT2,POU3F3,NKX2-1,LRRK2,FEZ1,SLITRK5,EFHC1,ATOH1,PLCB1,TSKU,NRG3,FAT4,MFSD2A,LAMB1,PTPRS,DLX2,BMP4,OXTR,NRP1,SEMA3A,CDH2,ATP2B4 |
| 1.152e-03 | -6.77 | V$E47_02 | MSigDB lists | V$E47_02 | 232 | 38 | 17377 | 1707 |
SCN5A,FGF13,RHOBTB1,KLHL13,IKZF2,HMCN1,ARHGAP44,SLC9A7,COL22A1,NUMBL,KCNN2,LRRN1,SLC7A11,MGAT1,MYC,STC2,MPPED2,TFAP2A,EPHB6,PPP2R2B,GATM,RIMS2,GLI1,RWDD2A,MEIS2,EDEM3,DUSP9,AIG1,PRKCQ,SNAP25,PLEKHB1,DDAH1,UNC5B,SHOX2,MMP16,FRMD5,FOXA1,MEF2C |
| 1.153e-03 | -6.76 | glucose catabolic process | biological process | GO:0006007 | 29 | 9 | 17256 | 1658 |
GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1 |
| 1.154e-03 | -6.76 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP | 148 | 27 | 17377 | 1707 |
PPP1R3D,ENAM,ARAP2,SH3BP2,MYO10,NR4A1,WLS,PTPN21,COBLL1,FAM102B,LRRC49,CHSY1,B4GALNT3,KBTBD11,DCBLD2,EPCAM,RUFY4,NAV1,LMLN,PDZD7,KMO,PLK2,ERN1,TSC22D1,SH3PXD2B,SPRY4,RNF122 |
| 1.156e-03 | -6.76 | Calcium Regulation in the Cardiac Cell | WikiPathways | WP536 | 151 | 29 | 5312 | 569 |
RGS16,GNG12,CACNA1E,GJB2,ADCY1,RGS20,RYR2,PRKCQ,PRKAR2B,ITPR2,ATP1B1,GRK6,RGS7,PRKCA,GJC1,GNAI1,RGS17,PRKCB,GNB4,GNAO1,PRKCD,RGS10,ADRB1,ADCY6,PKIA,ATP2B1,SFN,PRKACB,CHRM3 |
| 1.157e-03 | -6.76 | tubulin binding | molecular function | GO:0015631 | 347 | 52 | 17224 | 1680 |
MYO1D,EML5,PRKN,DNM3,FGF13,KIF5A,MYO1B,KIF5C,HDGFL3,KIF21B,DYNC1I1,MTUS1,FSD1,RAB11FIP5,MAP1A,GAS2L3,REEP1,MYO3B,MYH15,JAKMIP2,JAKMIP3,MYO6,FES,GLI1,DPYSL5,MID2,GAPDH,EML6,DCDC1,MYO10,LRRK2,SYBU,FEZ1,EFHC1,TTLL7,EML1,MAP10,GABARAPL1,SNCA,MAP1B,BEX4,IFT81,MAP2,CCDC181,ALDOA,MAP9,KIF21A,PPARGC1A,KIF1B,LZTS1,MID1,TPT1 |
| 1.157e-03 | -6.76 | GSE6875_WT_VS_FOXP3_KO_TREG_UP | MSigDB lists | GSE6875_WT_VS_FOXP3_KO_TREG_UP | 178 | 31 | 17377 | 1707 |
MXI1,ANKRD13D,FGF13,SEC24D,RNF144A,RAB6B,STAT4,ATOX1,APBB1,RASA3,HECW2,VIM,ADAMTS6,FAM117B,TNKS1BP1,BBS9,PFN2,PGAP1,COL27A1,BAIAP2,HSPA12B,GALNT1,IDI1,PIK3AP1,COL25A1,ITGB3,SHF,ZNF474,MOXD1,CKAP4,MAST1 |
| 1.157e-03 | -6.76 | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN | 178 | 31 | 17377 | 1707 |
XYLT1,TTYH2,PHACTR2,ATF3,CEBPA,COTL1,NPC2,ZDHHC14,TBC1D16,ADSSL1,SLC46A3,PGAP1,EYA4,SKI,RNF150,HMGCS1,FBXO32,MSMO1,SLC22A18,RAP2A,SGK3,VWA5A,PCK2,NRP1,ZFP36L2,SMPDL3A,LRP12,STOM,ATP1A3,HEY1,ABCG1 |
| 1.158e-03 | -6.76 | DUF3398 | pfam domains | PF11878 | 6 | 4 | 17054 | 1666 |
DOCK7,DOCK6,DOCK8,DOCK9 |
| 1.158e-03 | -6.76 | PET | pfam domains | PF06297 | 6 | 4 | 17054 | 1666 |
PRICKLE1,PRICKLE2,TES,LMCD1 |
| 1.158e-03 | -6.76 | Na_trans_cytopl | pfam domains | PF11933 | 6 | 4 | 17054 | 1666 |
SCN5A,SCN2A,SCN8A,SCN3A |
| 1.163e-03 | -6.76 | actin filament-based movement | biological process | GO:0030048 | 107 | 21 | 17256 | 1658 |
EPB41L5,SCN5A,ANK2,MYO1B,FGF12,RYR2,PKP2,VIM,KCND3,GJC1,KCNN2,SCN1B,WIPF3,CACNB2,TPM1,MYO6,MYRIP,FNBP1L,NEB,CACNA2D1,SHTN1 |
| 1.163e-03 | -6.76 | ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN | MSigDB lists | ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN | 764 | 101 | 17377 | 1707 |
EXPH5,NMNAT3,NBPF4,PAGE1,ACSL1,GRIK2,LPCAT2,DNAJC3,ARHGAP22,CTBP2,DOCK3,DENND3,IKZF2,RADIL,SLCO3A1,TIAM2,SCIN,FAM131B,SIPA1L2,PDZD8,ZNF438,KAZN,ZDHHC6,FABP6,SHF,MDH1B,WWC2,FANK1,PTPRE,SMAD9,THSD4,ANK2,PAGE5,MAGI3,NCKAP1L,LAMB1,MAP9,TANC2,MBOAT2,THOC3,KCTD1,HS6ST3,SV2B,WDR17,EDA2R,GRB14,OLAH,CLSTN2,KIF5C,PSD3,HERC5,CUEDC2,WDFY4,FHOD3,SPIRE1,NAV1,IGF1R,GATA2,GTSF1,CACNB2,RASD2,CPXM2,LIMCH1,MORN2,SH3PXD2B,ERRFI1,ESD,GLIS1,CHRM3,KIAA1211,DISC1,HBG2,MYO10,RAPGEF2,AGPAT4,EFHC2,GRID1,TTYH2,OBSCN,ST6GALNAC3,SDK1,ZFPM2,GALNT14,DHX32,TMCO3,SUGT1,VPS37D,MATN2,DYNC2LI1,MCC,SLCO5A1,PTPRN2,HOXD13,LRRK1,TRPC3,TBC1D4,PKIA,BTRC,FILIP1,OCLN,SLC43A1 |
| 1.165e-03 | -6.76 | GO_CELL_PROJECTION_ASSEMBLY | MSigDB lists | GO_CELL_PROJECTION_ASSEMBLY | 240 | 39 | 17377 | 1707 |
TNIK,WASF3,INPPL1,DNM3,TCTN2,CELSR3,RHOD,ITGA6,OPHN1,PIBF1,BBS9,RAC3,TTC30B,ABLIM1,LRRC6,EHD3,RAP2A,CTTN,DYNC2H1,DNAH5,SNX10,B9D1,INTU,DISC1,VAV3,TMEM67,ABCC4,SPATA6,RAPGEF2,SPATA13,TTC30A,ARHGEF26,ARMC4,IFT81,TMEM237,WDR19,DYNC2LI1,KLF5,FNBP1L |
| 1.166e-03 | -6.75 | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_DN | 163 | 29 | 17377 | 1707 |
PDK1,TCP11L2,SIDT1,MPP1,ST6GAL1,RAPGEF4,SELL,NPC2,GRK6,SESN1,SATB1,IKZF2,IRS2,ID3,ABLIM1,EEF2,RALGPS2,RPL28,MYC,INPP4B,ADCY6,TSPAN13,TOX,INPP5F,ST8SIA1,PACSIN1,RRAS2,AMPD1,ABCG1 |
| 1.166e-03 | -6.75 | V$EVI1_05 | MSigDB lists | V$EVI1_05 | 163 | 29 | 17377 | 1707 |
TYRO3,MEIS2,USP2,CHCHD7,ESRRG,PLAG1,ELOVL3,SATB2,CREB5,TMEM47,ZFPM2,IKZF2,MBNL2,HOXA1,HECTD2,ADPRHL1,FOXP2,RTN1,NCAM2,ADAMTS3,BACE2,GNAO1,HS3ST5,SH3BGRL2,IPCEF1,PPARGC1A,NRP1,TSPAN9,MID1 |
| 1.169e-03 | -6.75 | - | gene3d domains | 1.20.1270.60 | 72 | 17 | 8148 | 867 |
ARHGAP26,FER,PSTPIP2,ASAP3,PACSIN3,OPHN1,SNX9,BAIAP2,ARHGAP44,ICA1,SH3GL2,FCHO2,SRGAP1,PACSIN1,FNBP1L,FES,SNX7 |
| 1.169e-03 | -6.75 | PET_domain | interpro domains | IPR010442 | 6 | 4 | 18492 | 1811 |
PRICKLE1,PRICKLE2,TES,LMCD1 |
| 1.169e-03 | -6.75 | Liprin | interpro domains | IPR029515 | 6 | 4 | 18492 | 1811 |
PPFIA4,PPFIBP1,PPFIA2,PPFIBP2 |
| 1.169e-03 | -6.75 | DOCK_C/D_N | interpro domains | IPR021816 | 6 | 4 | 18492 | 1811 |
DOCK7,DOCK6,DOCK8,DOCK9 |
| 1.169e-03 | -6.75 | Na_trans_cytopl | interpro domains | IPR024583 | 6 | 4 | 18492 | 1811 |
SCN5A,SCN2A,SCN8A,SCN3A |
| 1.170e-03 | -6.75 | NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_8Q12_Q22_AMPLICON | 119 | 23 | 17377 | 1707 |
GDAP1,TMEM67,NECAB1,HNF4G,ESRP1,JPH1,ASPH,XKR9,MSC,MATN2,ZNF704,CDH17,SLCO5A1,LAPTM4B,GEM,NIPAL2,MMP16,RIMS2,PKIA,KCNB2,CRISPLD1,CHMP4C,HEY1 |
| 1.172e-03 | -6.75 | GO_BLOOD_VESSEL_MORPHOGENESIS | MSigDB lists | GO_BLOOD_VESSEL_MORPHOGENESIS | 353 | 53 | 17377 | 1707 |
EFNB2,ACVR1,ID1,FN1,FZD8,ARHGAP22,COL18A1,OVOL2,SLC12A6,EPHB1,NRXN1,PRKCA,NEDD4,TYMP,ITGB3,TSPAN12,DAB2IP,SYK,SLIT2,PDGFRB,NOS3,CYP1B1,VEGFC,VAV3,ADM2,FZD4,SH2D2A,NR4A1,CALCRL,YAP1,WNT11,PRDM1,ZFPM2,HOXA1,LEPR,JAM3,FGFR1,GPLD1,GJC1,HEG1,WARS,HPSE,PRCP,CCBE1,XBP1,HPGD,EGFL7,KLF5,BMP4,UNC5B,NRP1,CDH2,HEY1 |
| 1.174e-03 | -6.75 | V$CP2_01 | MSigDB lists | V$CP2_01 | 248 | 40 | 17377 | 1707 |
CREB3L2,ANKRD13B,IGFBP6,KIF5A,CLSTN2,ATP6V1E2,GATA3,ZIC2,CADM2,ABHD4,DDR1,TNKS1BP1,SATB1,DDIT4,RTN1,SPEG,KCTD15,MAP1A,KCNN2,EIF1,DAB2IP,PPP2R2B,PRR16,ENO1,GLI1,RHOQ,RNF145,TMEM43,PRDM13,DCHS1,SLITRK5,ATF3,CEBPB,NCKAP1L,TUFT1,DBP,CDH2,HOXB9,RAB30,DOCK9 |
| 1.174e-03 | -6.75 | V$OCT1_01 | MSigDB lists | V$OCT1_01 | 248 | 40 | 17377 | 1707 |
NEK10,ITPRIP,RHOBTB1,REL,CADM2,NRXN1,SEL1L3,HPCAL4,NEDD4,PPP2R3A,MTUS1,TRPS1,CDR2L,LRRN1,SLC7A11,COL25A1,LHX6,RAB26,MPPED2,PRKG1,SLC6A15,BEND4,TSPAN13,PDE4D,ETV1,DNAH5,PDGFRB,GAB2,NDUFA4L2,NR6A1,FZD4,NFIA,PYGO1,ATOH1,ID3,KLF12,MAP2K6,MCC,ZBTB20,MID1 |
| 1.176e-03 | -6.75 | GO_NEUTRAL_AMINO_ACID_TRANSPORT | MSigDB lists | GO_NEUTRAL_AMINO_ACID_TRANSPORT | 34 | 10 | 17377 | 1707 |
SERINC5,SLC3A2,SLC6A9,SLC36A1,SLC7A5,SERINC2,SLC36A4,SLC6A15,SLC1A5,SLC43A1 |
| 1.179e-03 | -6.74 | AACTGAC,MIR-223 | MSigDB lists | AACTGAC,MIR-223 | 91 | 19 | 17377 | 1707 |
CRIM1,NFIA,PRDM1,ATP1B1,MAP1B,F3,SLC35F1,EPB41L3,RALGPS2,KPNA3,IGF1R,KIAA0355,RAP2A,ACVR2A,PDE4D,MMP16,ATP2B1,SCN3A,MEF2C |
| 1.179e-03 | -6.74 | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | MSigDB lists | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | 91 | 19 | 17377 | 1707 |
PLA2G4A,PAK1,WASF3,VAV3,DNM3,MYO10,ASAP3,PRKCA,DOCK2,SCIN,PTPRC,GSN,PRKCB,AKT3,PRKCD,MARCKS,PLD1,SYK,GAB2 |
| 1.179e-03 | -6.74 | SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP | MSigDB lists | SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP | 91 | 19 | 17377 | 1707 |
EPHA3,NELL2,EVL,CELSR1,CLGN,PLK2,GALNT6,INPP4B,ATRNL1,GATA3,PSD3,KIF5C,LIN7A,ABAT,MAST4,SLC19A2,GFRA1,C9orf116,TBC1D19 |
| 1.179e-03 | -6.74 | GO_ACTION_POTENTIAL | MSigDB lists | GO_ACTION_POTENTIAL | 91 | 19 | 17377 | 1707 |
SCN5A,GRIK2,ANK2,CACNA1E,SCN8A,FGF12,PKP2,RYR2,ATP1B1,CACNB4,GJC1,KCNMB4,AKAP7,SCN1B,CACNB2,KCNMB3,SCN2A,SCN3A,CACNA2D1 |
| 1.182e-03 | -6.74 | TTTGCAC,MIR-19A,MIR-19B | MSigDB lists | TTTGCAC,MIR-19A,MIR-19B | 487 | 69 | 17377 | 1707 |
CCDC126,CGN,HECW2,STAT5B,GRK6,DOCK3,KIAA1217,ZFYVE9,F3,TRPS1,RTN1,MPPED2,NBEA,COL19A1,GULP1,TLN2,ETV1,IGFBP3,TBC1D8,DBN1,PNRC1,RNF145,SOX21,SHANK2,ADCY1,MFSD6,DCBLD2,ZNF711,ARHGAP21,HLF,KPNA3,DSEL,MAGI2,LPP,LONRF1,EFNB2,RUNX2,BMPR2,ROBO2,ITGA6,FZD8,BACE1,RIMKLA,NDFIP2,SPIRE1,SLC35F1,PRICKLE2,SGK1,VGLL4,MED12L,IGSF3,DPYSL5,RIN2,PCDH10,SYBU,RAPGEF4,PEX5L,ATP11A,ZFPM2,C3orf70,FNDC3A,ARRDC4,MBNL2,PLCB1,PMEPA1,SFMBT1,PGM2L1,LRRK1,SNPH |
| 1.183e-03 | -6.74 | CHOI_ATL_ACUTE_STAGE | MSigDB lists | CHOI_ATL_ACUTE_STAGE | 6 | 4 | 17377 | 1707 |
MET,MAGEA6,ETV1,MAGEA3 |
| 1.188e-03 | -6.74 | GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_BINDING | MSigDB lists | GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_BINDING | 112 | 22 | 17377 | 1707 |
ARAP2,MARK1,PLEKHA8,MYO10,STXBP6,PLEKHA5,CYTH3,MYO1B,FERMT2,PLEKHA1,APBA1,PFN2,PLCB1,SCIN,TECPR1,FCHO2,ZFYVE28,OSBPL5,DAB2IP,SH3PXD2B,CLVS2,GAB2 |
| 1.192e-03 | -6.73 | regulation of metal ion transport | biological process | GO:0010959 | 361 | 53 | 17256 | 1658 |
SCN5A,LGALS3,UBASH3B,NKAIN2,HECW2,LILRB1,PKP2,CACNB4,NEDD4,NOS1AP,LRRC55,KCNAB1,KCNN2,SCN1B,CNKSR3,CACNB2,EHD3,STC2,TRPC1,TSPAN13,PDE4D,HSPA2,PDGFRB,NOS3,ALG10B,DPP10,KCNIP3,ATF4,GSTM2,ANK2,PTPN6,HOMER2,JPH1,PACSIN3,FGF12,RYR2,GSTO1,ATP1B1,AMIGO1,HOMER3,SNCA,CXCL10,GNAO1,WFS1,KCNG1,GEM,ATG5,TRPC3,TESC,ATP2B4,CACNA2D1,STOM,CNTN1 |
| 1.194e-03 | -6.73 | LIM_MAMMARY_STEM_CELL_DN | MSigDB lists | LIM_MAMMARY_STEM_CELL_DN | 403 | 59 | 17377 | 1707 |
TFCP2L1,CGN,BTC,EHHADH,SIDT1,FGF13,ST14,ESRP1,DHCR24,BIK,PPFIBP2,GATA3,RHPN2,TDRKH,PKN1,TSPAN17,MTUS1,EPCAM,TLR3,CA2,GRHL1,SLC22A18,SLC10A7,TFAP2A,SNX10,TMEM56,TBC1D8,PAK1,SSH3,GCA,OPLAH,SH3BP2,SLC37A1,UROS,PTPN6,GJB2,HOMER2,PACSIN3,SPATA13,ATP1B1,CCNG1,BATF,ARRDC4,FRK,SLC46A3,ISG20,DHX32,SFXN1,ICA1,GSTO2,TUFT1,MAPK13,RNF130,SUSD4,DHCR7,MBOAT2,COBL,KIF1B,FOXA1 |
| 1.195e-03 | -6.73 | KANG_IMMORTALIZED_BY_TERT_DN | MSigDB lists | KANG_IMMORTALIZED_BY_TERT_DN | 98 | 20 | 17377 | 1707 |
MYO1D,NR4A1,ATP9A,EFNA3,MAFB,ZFPM2,FGFR1,TGFBR3,ADAMTS3,DLX6,THBS4,PDE10A,GHR,SVIL,SERPINI1,PDE4D,PPP2R2B,KLF9,NRP1,CDH2 |
| 1.195e-03 | -6.73 | GO_REGULATION_OF_EXTENT_OF_CELL_GROWTH | MSigDB lists | GO_REGULATION_OF_EXTENT_OF_CELL_GROWTH | 98 | 20 | 17377 | 1707 |
BDNF,DISC1,SEMA6B,FN1,BMPR2,FGF13,DCC,PLXNA2,NTRK3,SEMA6A,MAP1B,BCL11A,NKX6-1,RND2,SEMA4F,SEMA3C,CTTN,NRP1,SEMA3A,SEMA6C |
| 1.195e-03 | -6.73 | HALLMARK_ANDROGEN_RESPONSE | MSigDB lists | HALLMARK_ANDROGEN_RESPONSE | 98 | 20 | 17377 | 1707 |
FADS1,ABCC4,SEC24D,ARID5B,HOMER2,PTPN21,DHCR24,SCD,HMGCS1,IDI1,INSIG1,PMEPA1,CDC14B,TSC22D1,INPP4B,MAP7,HPGD,SGK1,LIFR,HMGCR |
| 1.196e-03 | -6.73 | calcium channel activity | molecular function | GO:0005262 | 120 | 23 | 17224 | 1680 |
TRPM4,GPM6A,CACNG3,CACNA1E,JPH1,MCOLN3,RYR2,RASA3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,CACNB2,TRPC1,GRIN2D,TMEM37,FAM155B,TRPC3,FAM155A,CACNA2D1,DENND5B |
| 1.197e-03 | -6.73 | WANG_HCP_PROSTATE_CANCER | MSigDB lists | WANG_HCP_PROSTATE_CANCER | 105 | 21 | 17377 | 1707 |
CD55,MEIS2,FN1,RHOD,SLC39A8,ASS1,WWC1,ATF3,FGFR1,RPL28,TACC2,ABCA5,STC2,CCNA1,TUFT1,SGK1,GRB10,LAMP3,CYP1B1,DUSP1,IGFBP3 |
| 1.197e-03 | -6.73 | V$EN1_01 | MSigDB lists | V$EN1_01 | 105 | 21 | 17377 | 1707 |
BDNF,CD55,SLC6A9,ANK2,SYNJ2BP,FGF17,SAV1,FNDC3A,PLCB1,EYA4,NEO1,HTR7,FOXP2,EFEMP1,IFT81,EOMES,LAPTM4B,DLG2,JAKMIP2,SH3BGRL2,RAPGEF5 |
| 1.200e-03 | -6.73 | GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN | 186 | 32 | 17377 | 1707 |
LATS2,UBASH3B,FAM117B,ITPR2,DOCK3,BCAN,KBTBD11,ZFYVE9,NEO1,TRPS1,PDE10A,CACNB2,EHD3,CCDC122,TSPAN13,VWA5A,ERRFI1,IGFBP3,VAV3,PTPRU,CYB5R2,VIM,PLS1,PRKCQ,NAP1L5,IGIP,PRKCB,AKT3,MAP9,RAI14,INPP5F,RRAGD |
| 1.200e-03 | -6.73 | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_TCONV_DN | 186 | 32 | 17377 | 1707 |
LATS2,FGF13,ATP8A1,ELOVL7,MCOLN3,SELL,RASL11B,ASS1,ADAMTS6,GABRR2,TSPAN17,QPRT,RPS6KA2,FRY,SLC30A4,CNKSR3,TOX,FAM84B,PRR16,ATP2B1,RIN2,RYR2,AGAP2,PEAK1,ATP10D,ID3,GNB4,C1orf21,HS3ST3B1,NRP1,FNBP1L,CTNND2 |
| 1.200e-03 | -6.73 | GSE39556_CD8A_DC_VS_NK_CELL_DN | MSigDB lists | GSE39556_CD8A_DC_VS_NK_CELL_DN | 186 | 32 | 17377 | 1707 |
RGS16,RHOBTB1,TBC1D1,ST6GAL1,XYLT1,PTPN21,SETBP1,TJP1,RPS6KA2,PPP1R26,KMO,HRK,FIG4,AGL,RAPGEF5,RASGRP1,ATP2B1,CAND2,BCL7A,VNN2,CD55,GPM6A,TES,LRMP,ROR1,HERPUD1,PLAGL1,KIAA0355,PRKCB,DYNC2LI1,TNFRSF17,ACSM3 |
| 1.200e-03 | -6.73 | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_DN | MSigDB lists | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_BCL6_HET_DN | 186 | 32 | 17377 | 1707 |
ELOVL4,TSPAN15,RHOD,RECK,FHDC1,HERC6,AARS,MCF2L,GFI1,RASGRP1,MED12L,HBG2,FER,TUBA1A,GJB2,C3orf52,SHISA2,SMPDL3B,CEBPB,ENPP1,PLK2,GNB4,MFSD2A,XBP1,MAPK13,DLX2,SLC22A15,HS3ST3B1,FNBP1L,DOCK6,SLC16A10,DIRC2 |
| 1.200e-03 | -6.73 | GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP | MSigDB lists | GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP | 186 | 32 | 17377 | 1707 |
PAK1,MOCOS,GCA,SH3BP2,EVL,ATP8A1,SPATA6,BLVRB,ATOX1,LMCD1,SPATA13,HERC6,IKZF2,RERE,QPRT,ISG20,OTUD1,SETDB2,CA2,GYPC,PLAGL1,NACC2,CSF1,PRKCD,STC2,SRD5A3,NCOA7,DYNC2LI1,PTPRS,CMPK2,TLR4,FES |
| 1.200e-03 | -6.73 | GSE3982_DC_VS_MAC_DN | MSigDB lists | GSE3982_DC_VS_MAC_DN | 186 | 32 | 17377 | 1707 |
PRKAA2,MYO1D,GNG12,MLF1,ITGA6,RGS20,BEGAIN,NRN1,HERC6,SLC9A7,UNC13B,CDC14B,TSC22D1,MYO6,PNMA2,GDAP1,VNN2,PNP,SPATA6,MAFB,HEG1,SNCA,TRIM9,RND3,NACC2,CSF1,FAM114A2,WWTR1,WDR19,NXPH4,PKIA,MME |
| 1.200e-03 | -6.73 | GSE29618_BCELL_VS_PDC_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DN | 186 | 32 | 17377 | 1707 |
RUNX2,ALOX5AP,ST14,DNAJC3,VAMP8,GAS6,EPHB1,RGS7,CANX,IL18R1,RPS6KA2,MAP1A,SLC7A11,TM9SF2,PTPRE,PFKFB2,DSTN,NPC2,ASPH,CRYBG3,HERPUD1,MAPKAPK2,GSN,ERN1,AHNAK2,SH3BP4,SLC7A5,PTPRS,SEMA3C,RNF130,NRP1,TBC1D4 |
| 1.200e-03 | -6.73 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | 186 | 32 | 17377 | 1707 |
RUNX2,ALOX5AP,SIDT1,ST14,LILRB1,HERC5,GAS6,EPHB1,IL18R1,MAP1A,SLC7A11,GFI1,PTPRE,ALDH2,CRIM1,DSTN,CRYBG3,MAPKAPK2,GSN,MAP2K6,AHNAK2,MCC,SH3BP4,SLC7A5,PTPRS,KIAA0513,SEMA3C,RNF130,SLC1A5,NRP1,TBC1D4,ATP2B4 |
| 1.201e-03 | -6.72 | SH3_9 | pfam domains | PF14604 | 78 | 17 | 17054 | 1666 |
ARHGAP26,TNK2,SORBS1,DOCK1,UBASH3B,PACSIN3,SORBS3,ARHGAP32,BAIAP2,ARHGEF26,SH3RF1,ABI3,MAP3K21,SH3BP4,CTTN,PACSIN1,NEB |
| 1.204e-03 | -6.72 | regulation of apoptotic process | biological process | GO:0042981 | 1570 | 186 | 17256 | 1658 |
TRIM2,ACVR1,GRIK2,DNAJC3,TNFAIP8L2,LILRB1,GATA3,NPM1,STAT5B,PRKCA,AARS,EYA4,STK24,F3,TXNDC5,GSDME,BAG3,RPS6KA2,PMAIP1,HRK,CTTN,EPHB6,FANK1,ENO1,SLIT2,POU3F3,PDGFRB,LAMP3,CYP1B1,ATF4,COL4A3,ACVR1C,LRRK2,BNIP3L,DEPTOR,YAP1,AGO4,ROR1,SGK2,SAV1,ARHGEF26,INHBC,GSN,SH3RF1,NCKAP1L,PLK2,RASGRF2,TNFRSF1A,BBC3,ERCC5,NRP1,UNC5B,PPARGC1A,MEF2C,BCL11B,PRKAA2,TYRO3,LATS2,LGALS3,GABRB2,ITGA6,SLK,DHCR24,SLC25A27,TNFRSF10C,GAS1,SYCP2,BNIP1,IGF1R,GATA2,MYC,PRELID1,LRP6,BNIP3,STXBP1,ZNF385A,NOS3,HMGCR,PAK1,FGFR4,RPL26,UNC5C,BDNF,ATP5IF1,MSTN,FHL2,OBSCN,STRADB,HIP1,FAM162A,HERPUD1,INHBE,SFN,EPHA3,PRKN,BTC,ID1,COL18A1,NTRK3,DDR1,TIAM2,SCIN,TLR3,ASNS,UNC13B,MAGEA3,BCL6,DAB2IP,STEAP3,MET,PERP,SNAI2,DOCK8,CTH,IGFBP3,PRAME,GAPDH,NOP53,NKX3-2,PREX1,PRKCQ,WNT11,ATF3,ATOH1,CD40,FGFR1,SNCA,IRS2,SMAD3,IKZF3,BEX3,WFS1,MAP3K21,HPGD,TNFSF15,HGF,BMPR1A,ATG5,RETREG1,TNIK,DYRK3,ARHGEF11,PAK5,APBB1,BIK,GAS6,EPHB1,TPD52L1,BMP6,BEX2,MCF2L,PRKCD,TFAP2A,SGK3,SGK1,YBX3,SMAD6,TNFRSF11A,SPRY2,PNMA2,DUSP1,SLC40A1,VAV3,CARD6,MSX1,RAPGEF2,NUGGC,NUAK2,AGAP2,RACK1,MGMT,GPLD1,DKK1,CEBPB,ID3,NACC2,TERT,ACER2,MAP2K6,XBP1,PCGF2,BMP4,MAP3K20,DDIT3,FOXA1,TPT1 |
| 1.206e-03 | -6.72 | GU_PDEF_TARGETS_UP | MSigDB lists | GU_PDEF_TARGETS_UP | 71 | 16 | 17377 | 1707 |
SMAD3,MAPKAPK2,COL6A2,FN1,DOCK1,FZD4,FZD8,ITGA6,COL4A5,VIM,SERPINI1,PRKCA,CDH2,RAC3,SNAI2,FZD1 |
| 1.206e-03 | -6.72 | GO_REGULATION_OF_SYNAPSE_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_SYNAPSE_ASSEMBLY | 71 | 16 | 17377 | 1707 |
BDNF,ROBO2,SLITRK2,CLSTN2,SLITRK5,NTRK3,AMIGO1,NRXN1,EPHB1,CBLN1,PPP1R9A,DKK1,LRRN1,FLRT3,OXTR,MEF2C |
| 1.212e-03 | -6.72 | regulation of protein kinase activity | biological process | GO:0045859 | 800 | 103 | 17256 | 1658 |
NEK10,ACSL1,AVPI1,FGF13,DUSP8,DNAJC3,NPM1,CEBPA,NTRK3,LCP2,SNX9,PIBF1,PPP1R9A,STK24,PPM1E,TLR3,ZFYVE28,ITGB3,DAB2IP,TLR4,PRKACB,RASGRP1,PDGFRB,SESN2,FZD4,PTPN6,TGFA,LRRK2,PREX1,ADCY1,DEPTOR,PRKAR2B,WNT11,ACVR2B,CD40,FGFR1,SNCA,WARS,CAMK2N1,CXCL10,NRG3,PTPRJ,GPRC5B,NCKAP1L,ERN1,WWTR1,MAP3K21,DUSP19,TNFSF15,HGF,DIRAS1,SPRY4,MAPK10,CACUL1,TENM1,LATS2,TNIK,PAK5,SLK,FZD8,UBASH3B,IPO5,HERC5,GAS6,PKN1,TPD52L1,IGF1R,FLRT3,PRKCD,GHR,LRP6,ADCY6,INAVA,AFAP1L2,ERRFI1,IQGAP3,TNFRSF11A,SYK,SPRY2,DUSP1,HMGCR,PAK1,RAPGEF2,VLDLR,STRADB,DUSP9,CCNG1,RACK1,TLR6,DKK1,MAPKAPK2,PTPRC,TRIB3,FGR,CSF1,MAP2K6,BMP4,SMYD3,MAP3K20,TESC,ATP2B4,PKIA,SFN |
| 1.220e-03 | -6.71 | Adrenergic signaling in cardiomyocytes | KEGG pathways | hsa04261 | 144 | 27 | 7161 | 730 |
CREB3L2,SCN5A,ATF4,CACNG3,RAPGEF4,ADCY1,RYR2,CREB5,ATP1B1,PRKCA,CACNB4,PLCB1,PPP2R3A,GNAI1,SCN1B,AKT3,CACNB2,ADRB1,ADCY6,MAPK13,PPP2R2B,TPM1,PRKACB,ATP2B4,ATP2B1,CACNA2D1,ATP1A3 |
| 1.220e-03 | -6.71 | Adrenergic signaling in cardiomyocytes | KEGG pathways | ko04261 | 144 | 27 | 7161 | 730 |
CREB3L2,SCN5A,ATF4,CACNG3,RAPGEF4,ADCY1,RYR2,CREB5,ATP1B1,PRKCA,CACNB4,PLCB1,PPP2R3A,GNAI1,SCN1B,AKT3,CACNB2,ADRB1,ADCY6,MAPK13,PPP2R2B,TPM1,PRKACB,ATP2B4,ATP2B1,CACNA2D1,ATP1A3 |
| 1.221e-03 | -6.71 | GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1638 | 197 | 17377 | 1707 |
PPP4R4,ACVR1,ACSL1,DUSP8,FGF13,GRIK2,DNAJC3,GATA3,NPM1,NDRG2,CEBPA,PRKCA,SNX9,NOS1AP,TRPS1,SKI,PPM1E,PPP1R26,ZFYVE28,ITGB3,RAP2A,PPP2R2B,TLR4,SLIT2,RASGRP1,PRKACB,PDGFRB,TNK2,SESN2,GCNT2,SPOCD1,TGFA,LRRK2,DEPTOR,PRKAR2B,ACVR2B,INHBC,ENPP1,GPRC5B,NCKAP1L,SH3RF1,ERN1,TNFRSF1A,BMP1,DIRAS1,INPP5F,SPRY4,NRP1,PPARGC1A,MAGI2,MEF2C,LATS2,FN1,FBXO4,JDP2,UBASH3B,SORBS3,TNFRSF19,PFN2,DDIT4,MECOM,RNF180,IGF1R,FRY,GATA2,FLRT3,MYC,C1QL4,SREBF1,LRP6,ADCY6,HMGCR,FGFR4,PAK1,DISC1,MSTN,VLDLR,DUSP9,WWC1,STRADB,ARRDC4,PLCB1,HERPUD1,MAPKAPK2,PMEPA1,PELI2,CSF1,THBS4,INHBE,CDH2,TESC,SMYD3,SFN,NEK10,ID1,AVPI1,CELSR3,IL15,AKAP5,NTRK3,LCP2,PIBF1,PPP1R9A,TLR3,CDC14B,CNKSR3,DACT1,BCL6,ACVR2A,DAB2IP,MARCKS,PDE4D,HSPA2,SNAI2,FZD1,IGFBP3,FER,FZD4,PTPN6,ADCY1,WNT11,ATF3,SYNJ2BP,RARRES2,CD40,FGFR1,MAGI3,SNCA,SMAD3,CAMK2N1,CXCL10,NRG3,PTPRJ,GBP1,WFS1,WWTR1,ITGA2,DUSP19,TNFSF15,HGF,BMPR1A,ATG5,MAPK10,MID1,CNTN1,MYO1D,TNIK,FARP1,BMPR2,EDA2R,FZD8,LRP4,HERC5,P2RY1,GAS6,PKN1,NDFIP2,EPHB1,TPD52L1,BMP6,PPP2R3A,RASD2,PRKCD,GHR,AFAP1L2,IQGAP3,ERRFI1,GFI1,SMAD6,TNFRSF11A,SPRY2,SYK,DUSP1,MOB1B,VEGFC,RAPGEF2,PRICKLE1,CCNG1,TLR6,GPLD1,DKK1,GPR37,PTPRC,TRIB3,NSD1,FGR,DOCK7,MYADM,ACER2,MAP2K6,XBP1,DLG2,LRRK1,BMP4,PKIA,BTRC,ATP2B4 |
| 1.221e-03 | -6.71 | forebrain neuron differentiation | biological process | GO:0021879 | 53 | 13 | 17256 | 1658 |
BCL11B,ROBO2,GATA2,RAPGEF2,LHX6,SATB2,DLX2,NRP1,FOXG1,SEMA3A,SLIT2,RAC3,NKX2-1 |
| 1.221e-03 | -6.71 | regulation of cholesterol metabolic process | biological process | GO:0090181 | 53 | 13 | 17256 | 1658 |
CYP51A1,IDI1,MVK,HMGCS1,MVD,LDLR,SREBF1,FASN,SQLE,SCD,DHCR7,ABCG1,HMGCR |
| 1.221e-03 | -6.71 | cellular response to drug | biological process | GO:0035690 | 303 | 46 | 17256 | 1658 |
PRKAA2,PRKN,ID1,ASS1,ITPR2,GAS6,ADSSL1,DDIT4,PPM1E,FBXO32,TLR3,MYC,PRKCD,RAP2A,ADCY6,BNIP3,KLF9,PCK2,ERRFI1,SLIT2,CHRM3,CYP1B1,TRPM4,MSX1,ATF4,GSTM2,MSTN,LRRK2,ADCY1,RYR2,ABCC2,PLEKHA1,PLCB1,BAIAP2,GNAI1,GPLD1,EIF4EBP1,ACER2,RGS10,PCGF2,MAPK13,PPARGC1A,CERS1,SMYD3,LARP1,MEF2C |
| 1.221e-03 | -6.71 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_DN | 171 | 30 | 17377 | 1707 |
SYNPO2,TRIM2,RAPGEF2,TGFA,CYB5R2,CMTM8,PTPN21,C20orf194,NDRG2,SHISA2,ANKRD18A,ATF3,KIAA1217,KCNC4,ATP10D,FHOD3,FBXO32,PLEKHH2,PDLIM3,RND3,CDC14B,MAP2,NCOA7,ACTA2,STEAP3,OXTR,MET,MID1,GATM,DUSP1 |
| 1.221e-03 | -6.71 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN | 171 | 30 | 17377 | 1707 |
ATL1,GCA,NMNAT3,TRIM2,PDK1,ELOVL4,CHCHD7,ARHGEF11,CYP2J2,PLAG1,SPATA6,PPFIBP2,UBAC2,EFHC1,CBY1,ARHGAP32,TEX9,DDX60L,ZNF569,ZNF711,CACHD1,IGF1R,LRRN1,FMO4,PPFIBP1,OSBPL5,SCRN1,NBEA,TMOD2,PJA1 |
| 1.221e-03 | -6.71 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_UP | 171 | 30 | 17377 | 1707 |
RGS16,ACSL1,MYO10,GJB2,AGPAT4,ELOVL7,AK4,HECW2,SAV1,DENND3,PHLDA2,F3,CDS1,RASSF8,PMEPA1,MFSD2A,CNKSR3,AKT3,MAP7,TNFSF15,HS3ST3B1,SH3PXD2B,TBC1D9,MET,PRR16,IL1RAP,PTGES,KIAA1211,SMPDL3A,HEY1 |
| 1.224e-03 | -6.71 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | 156 | 28 | 17377 | 1707 |
SLC40A1,FARP1,SLC39A8,GATA3,RNF125,HECW2,KCTD12,ARHGAP32,FAM13A,NDFIP2,C4orf19,SATB1,CHST10,MTUS1,GNAI1,IFT81,EOMES,MFSD9,SLC7A11,DACT1,FRAS1,XBP1,GTF2F2,PTPRE,SNX10,MMP16,RASGRP1,RAB30 |
| 1.225e-03 | -6.70 | PTPN13 (protein tyrosine phosphatase, non-receptor type 13) | protein interactions | 5783 | 63 | 15 | 17029 | 1718 |
EFNB2,CGN,LATS2,RALGPS2,BEX3,RAPGEF2,CRIP2,GHR,NSD2,CBY1,PLEKHA1,LPIN3,FBXL2,TANC2,HEY1 |
| 1.226e-03 | -6.70 | MAGI2 (membrane associated guanylate kinase, WW and PDZ domain containing 2) | protein interactions | 9863 | 18 | 7 | 17029 | 1718 |
SMAD3,ACVR2A,MAGI2,RAPGEF2,TGFA,CTNND2,ADRB1 |
| 1.233e-03 | -6.70 | V$ELF1_Q6 | MSigDB lists | V$ELF1_Q6 | 225 | 37 | 17377 | 1707 |
ALOX5AP,REL,ITPR2,SEZ6L2,PKN1,SEL1L3,IKZF2,GDPD5,NEDD4,RPL34,KCNAB1,KCNMB3,MPPED2,MARCKS,IPCEF1,NCAM1,TLR4,TBC1D8,PFKFB4,ITGB7,MICAL2,NFIA,CALCRL,VIM,CD37,PLEKHH2,IKZF3,TMEM154,MYADM,KLF12,NCKAP1L,CSF1,EIF4EBP1,ABI3,INPP5F,NRP1,MLLT3 |
| 1.233e-03 | -6.70 | V$POU1F1_Q6 | MSigDB lists | V$POU1F1_Q6 | 225 | 37 | 17377 | 1707 |
TYRO3,PTPRD,RHOD,SYT12,FZD8,APBB1,FHDC1,PRDM8,ZIC2,CREB5,GRK6,IKZF2,TRPS1,FOXP2,BACE2,FLRT3,ZIC5,ATRNL1,CCDC122,JAKMIP2,VGLL4,C15orf41,MEIS2,CRIM1,ESRRG,NPM3,FGF12,ELMOD1,DUSP9,WNT11,NAALADL2,ZIC1,DOCK7,MAP2,BMP4,NRP1,PCSK5 |
| 1.237e-03 | -6.70 | GSE17721_LPS_VS_CPG_2H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_2H_BMDC_UP | 194 | 33 | 17377 | 1707 |
SEC24D,LRP4,APBB1,ASS1,NPM1,SEL1L3,PCDH7,PLS3,SOAT2,REEP1,EEPD1,TSC22D1,POF1B,GSTM3,ACVR2A,TSPAN13,TNFRSF11A,DUSP1,FER,RAB3B,MPP1,CALCRL,PEAK1,TRIM34,GYPC,RND3,PLK2,SVIL,GEM,CMPK2,KIF1B,LARP1,TLL2 |
| 1.237e-03 | -6.70 | PLASARI_TGFB1_TARGETS_10HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_UP | 194 | 33 | 17377 | 1707 |
CREB3L2,RGS16,MYO1D,RASL11B,ASS1,LPIN3,HECTD2,FBXO32,PMAIP1,ITGB3,PRKG2,KLHL29,HSPA2,GATM,CTH,MICAL2,GCNT2,GJB2,SPATA13,NUAK2,WNT11,CD40,GALNT3,ENPP1,PMEPA1,THBS4,MFSD2A,HEYL,ENTPD7,HK2,UNC5B,SFN,HEY1 |
| 1.237e-03 | -6.70 | GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_UP | MSigDB lists | GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_UP | 194 | 33 | 17377 | 1707 |
TFCP2L1,ACSL1,EHHADH,PRSS12,PKP2,COL18A1,IGF2BP2,PHLDA2,FHOD3,TUBB4A,LRRC6,EEF2,REEP1,FAM107B,SGK1,BARX1,IGFBP3,ATF4,COL4A3,MEF2B,GSTO1,GPLD1,PTPRJ,MYADM,TERT,CCNA1,ADRB1,RAB31,MAOA,HOXB9,MID1,KIF1B,FOXA1 |
| 1.237e-03 | -6.70 | HALLMARK_KRAS_SIGNALING_UP | MSigDB lists | HALLMARK_KRAS_SIGNALING_UP | 194 | 33 | 17377 | 1707 |
RGS16,BTC,PCSK1N,CFH,FBXO4,ST6GAL1,KIF5C,SATB1,DOCK2,EPB41L3,CA2,SCN1B,MAP7,PRKG2,TSPAN13,VWA5A,ETV1,CPE,SPRY2,IGFBP3,MAFB,SNAP25,PRDM1,DCBLD2,GALNT3,CD37,CXCL10,GPRC5B,GYPC,ITGBL1,ITGA2,CAB39L,NRP1 |
| 1.238e-03 | -6.69 | forebrain generation of neurons | biological process | GO:0021872 | 66 | 15 | 17256 | 1658 |
BCL11B,NUMBL,ROBO2,GATA2,RAPGEF2,LHX6,SATB2,DLX2,NRP1,FOXG1,SEMA3A,SLIT2,RAC3,FGFR1,NKX2-1 |
| 1.238e-03 | -6.69 | cranial skeletal system development | biological process | GO:1904888 | 66 | 15 | 17256 | 1658 |
SMAD3,IRX5,RUNX2,INSIG1,FOXN3,WDR19,TFAP2A,SH3PXD2B,DLX2,BMP4,COLEC10,HOXA1,MMP16,SIX2,MEF2C |
| 1.239e-03 | -6.69 | GO_SINGLE_ORGANISM_CELLULAR_LOCALIZATION | MSigDB lists | GO_SINGLE_ORGANISM_CELLULAR_LOCALIZATION | 863 | 112 | 17377 | 1707 |
DOC2A,FGF13,GRIK2,SYT12,PKP2,SYT14,NRXN1,CANX,NUP62CL,PIBF1,DOCK2,PCLO,ZFYVE9,TRPS1,EPB41L3,SEC16B,UNC13B,PMAIP1,REEP1,RAP2A,RAB26,BCL6,ZDHHC23,MAP7,LIN7A,PACSIN1,RAB27B,RPL26L1,CPE,RASGRP1,KCNB2,RPS13,DPP10,GDAP1,ITGB7,KCNIP3,ANK2,TGFA,LRRK2,TRAM1L1,SYNJ2BP,ATP1B1,RAB38,SNCA,TRIM9,RANBP2,ARHGAP21,KPNA3,TNFRSF1A,BBC3,SEPT5,MAGI2,STON2,TC2N,CHMP4C,RPS20,TNIK,TSPAN15,SEC24D,LRP4,IPO5,OPHN1,GPSM2,P2RY1,GAS6,DYNC1I1,TSPAN17,RPL13A,NEDD4,SPIRE1,RPL34,GATA2,BHLHA15,CACNB2,RPS11,EHD3,LRP6,PRKG2,CADPS2,SH3PXD2B,STXBP1,SPRY2,SYK,RIMS2,RPS23,RPL26,RAPGEF2,RPL21,MEI1,PRICKLE1,FERMT2,PEX5L,SNAP25,SKAP1,MAP1B,RERE,RPL12,MYADM,SH3GL2,RPL28,FCHO2,WDR19,RAB31,DLG2,RPS12,RPL4,FNBP1L,CDH2,TESC,KIF1B,SIX2,SNPH |
| 1.239e-03 | -6.69 | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | MSigDB lists | GUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN | 52 | 13 | 17377 | 1707 |
COL9A3,ID3,CELSR1,FRY,SFMBT1,MARS,INPP5F,ROR1,SPATS2L,COL9A2,WARS,IGSF3,LPP |
| 1.241e-03 | -6.69 | EGF_3 | prosite domains | PS50026 | 195 | 35 | 12060 | 1278 |
TENM1,BTC,CELSR1,CELSR3,CNTNAP3,LDLR,SELL,GAS6,BCAN,NRXN1,DNER,HMCN1,EFEMP1,NELL2,VWDE,SCARF2,ATRNL1,PROS1,NTNG1,SLIT2,TGFA,VLDLR,F12,HEG1,NRG3,FAT4,FBN1,CCBE1,THBS4,FAT1,MATN2,BMP1,EGFL7,TMEFF2,TLL2 |
| 1.243e-03 | -6.69 | positive regulation of cell migration | biological process | GO:0030335 | 490 | 68 | 17256 | 1658 |
AMOTL1,ACVR1,DOCK1,RHOD,ATP8A1,COL18A1,GATA3,NTRK3,PRKCA,SEMA6A,F3,TCAF2,ITGB3,DAB2IP,MET,DOCK8,SNAI2,PDGFRB,FER,GCNT2,PREX1,WNT11,RARRES2,CD40,DOCK5,FGFR1,IRS2,SMAD3,CXCL10,NCKAP1L,CCBE1,PLK2,APELA,ITGA2,LAMB1,HGF,SEMA3C,NRP1,LGALS3,BMPR2,FN1,ITGA6,GAS6,SEMA4F,IGF1R,GATA2,RRAS2,SPRY2,NOS3,VEGFC,PAK1,EPB41L5,RAPGEF2,RACK1,GPLD1,PTPRC,FGR,DOCK7,MYADM,RIPOR2,TERT,AKT3,CSF1,THBS4,XBP1,BMP4,SEMA3A,SHTN1 |
| 1.243e-03 | -6.69 | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 134 | 25 | 17377 | 1707 |
PAK1,SERINC5,ATF4,TCP11L2,SIDT1,ACVR1C,NUAK2,GSTO1,ATP1B1,DDR1,SNX9,NEDD4,IRS2,ID3,SIPA1L2,OTUD1,SLC30A4,MPP7,CFHR1,TSC22D1,SGK1,PROS1,TMEM120B,AMPD1,DUSP1 |
| 1.243e-03 | -6.69 | KRAS.300_UP.V1_UP | MSigDB lists | KRAS.300_UP.V1_UP | 134 | 25 | 17377 | 1707 |
DNM3,KIF5A,KIF5C,SNAP25,DYNC1I1,GPR19,CTNNA2,DCBLD2,RTN1,HTR7,ITGBL1,TERT,SCN1B,ITGA2,SLCO5A1,SLC6A15,FAM155B,SCN2A,MAPK10,SEMA3A,ETV1,SPRY2,GLDC,HEY1,RRAGD |
| 1.252e-03 | -6.68 | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | MSigDB lists | WEINMANN_ADAPTATION_TO_HYPOXIA_DN | 40 | 11 | 17377 | 1707 |
GPR37,VEGFC,PLA2G4A,ID3,CD55,STC2,MARCKS,TPM1,HSPA2,IL18R1,IGFBP3 |
| 1.252e-03 | -6.68 | MODULE_70 | MSigDB lists | MODULE_70 | 40 | 11 | 17377 | 1707 |
SMAD3,DBN1,SCN5A,COL9A3,PDE1B,SH3GL2,DSG2,BMP1,LILRB1,TRPC1,GAS6 |
| 1.252e-03 | -6.68 | GO_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 40 | 11 | 17377 | 1707 |
SMAD3,TRIB3,ENPP1,INSIG1,GATA2,JDP2,WWTR1,C1QL4,GATA3,ZFPM2,DDIT3 |
| 1.252e-03 | -6.68 | HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_IMMATURE_TO_MATURE_B_LYMPHOCYTE_UP | 40 | 11 | 17377 | 1707 |
TGFBR3,RAB6B,CSF1,STAT4,CR2,ARL2,SELL,RABAC1,ZFPM2,PCK2,STOM |
| 1.252e-03 | -6.68 | negative regulation of protein modification process | biological process | GO:0031400 | 604 | 81 | 17256 | 1658 |
PHACTR3,PRKN,PPP4R4,DUSP8,DNAJC3,NPM1,NDRG2,CEBPA,NTRK3,PIBF1,SKI,PPM1E,PPP1R26,ZFYVE28,CNKSR3,DACT1,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,PTPN6,LRRK2,PREX1,DEPTOR,ATF3,PRKAR2B,SYNJ2BP,SNCA,WARS,CAMK2N1,ENPP1,PTPRJ,NCKAP1L,GBP1,WWTR1,NCOA7,DUSP19,HGF,INPP5F,SPRY4,ATG5,PPARGC1A,PRKAA2,LATS2,UBASH3B,IPO5,PKN1,DDIT4,MECOM,FRY,IGF1R,FLRT3,MYC,PRKCD,RASD2,C1QL4,LRP6,ERRFI1,SMAD6,SPRY2,BOD1,DUSP1,HMGCR,DUSP9,PHACTR2,RACK1,DKK1,BEX4,PTPRC,TRIB3,MYADM,PMEPA1,ACER2,LRRK1,BMP4,TESC,SMYD3,PKIA,SFN,ATP2B4 |
| 1.258e-03 | -6.68 | human chr2q31.1 | chromosome location | human chr2q31.1 | 75 | 14 | 26185 | 1967 |
CHN1,PDK1,KLHL23,GPR155,ITGA6,RAPGEF4,MYO3B,HOXD13,DLX2,MAP3K20,HAGLR,METAP1D,LINC01116,LOC101926913 |
| 1.267e-03 | -6.67 | MELLMAN_TUT1_TARGETS_DN | MSigDB lists | MELLMAN_TUT1_TARGETS_DN | 46 | 12 | 17377 | 1707 |
ALDH2,KLF12,MGST3,CCNA1,PACSIN3,KLF5,BNIP3,KLF9,PACSIN1,SNX10,RAC3,CPEB1 |
| 1.267e-03 | -6.67 | PENG_GLUCOSE_DEPRIVATION_UP | MSigDB lists | PENG_GLUCOSE_DEPRIVATION_UP | 46 | 12 | 17377 | 1707 |
CEBPB,CARS,ASNS,MSMO1,CTTN,POU2F2,PCK2,AARS,OCLN,WARS,PYCR1,C2orf27A |
| 1.268e-03 | -6.67 | positive regulation of bone mineralization | biological process | GO:0030501 | 35 | 10 | 17256 | 1658 |
SMAD3,ACVR1,BMPR2,TFAP2A,ACVR2A,BMPR1A,BMP4,ACVR2B,BMP6,MEF2C |
| 1.268e-03 | -6.67 | synaptic vesicle endocytosis | biological process | GO:0048488 | 35 | 10 | 17256 | 1658 |
DNM3,SH3GL2,FCHO2,DNAJC6,OPHN1,NLGN4X,PACSIN1,CANX,STON2,SNCA |
| 1.271e-03 | -6.67 | GSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP | 179 | 31 | 17377 | 1707 |
B9D1,MN1,RHOBTB1,VLDLR,EFHC2,IPO5,PKP2,AK4,PRKAR2B,ARRDC4,PHGDH,PCLO,NEDD4,GPR150,RNF150,ARHGAP21,PTPRJ,RNF217,NCKAP1L,ALDOC,RAP2A,ALDH1L1,ZNF704,OPN3,HK2,KLF9,SH3PXD2B,RAB27B,DOCK6,CKAP4,PCSK6 |
| 1.271e-03 | -6.67 | EGFR_UP.V1_UP | MSigDB lists | EGFR_UP.V1_UP | 179 | 31 | 17377 | 1707 |
PDLIM7,RGS16,VAV3,ARAP2,RHOQ,ARID5B,FERMT2,IGF2BP2,ATF3,COTL1,SEL1L3,MBNL2,ASPH,ISG20,ENPP1,PLAGL1,SLC7A11,PMAIP1,BACE2,GBP1,ITGA2,HK2,KCNS3,MAOA,CADPS2,PTPRE,HSPA2,CEBPD,CYP1B1,LPP,TBC1D8 |
| 1.271e-03 | -6.67 | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP | 179 | 31 | 17377 | 1707 |
UST,RPS20,GCA,TNK2,VAV3,RPL26,RECK,RBFOX2,PSTPIP2,PRRG1,CR2,ENAH,RGS7,RNF44,FRK,SLC46A3,LEPR,RPL13A,MAGEA12,FRY,KMO,KIAA0355,CSF1,AHNAK2,TFAP2A,FIG4,DYNC2H1,RPS12,SYNGR3,RPS23,PKIA |
| 1.275e-03 | -6.66 | V$IK1_01 | MSigDB lists | V$IK1_01 | 257 | 41 | 17377 | 1707 |
DOC2A,FGF13,OTX1,SORBS3,IL13RA1,APBA1,SEMA6A,CYP26A1,MCU,ATXN7L1,KCNAB1,PDE10A,LHX6,ZIC5,TFAP2A,TRPC1,POU3F3,NKX2-1,MID2,MSX1,GPM6A,TES,PRDM1,ACVR2B,ATP1B1,FGF17,ZFPM2,SAV1,NSD1,KPNA3,TNFSF15,BMP4,FNBP1L,LIFR,NR3C2,MMP16,PURG,COBL,FILIP1,ATP2B4,ATP1A3 |
| 1.277e-03 | -6.66 | LEE_TARGETS_OF_PTCH1_AND_SUFU_DN | MSigDB lists | LEE_TARGETS_OF_PTCH1_AND_SUFU_DN | 78 | 17 | 17377 | 1707 |
PAK1,PCSK1N,KIF5A,ELMOD1,CLSTN2,ATP1B1,SEZ6L2,CA8,ASPH,CBLN1,TSPAN17,CDS1,ABLIM1,HMGCS1,HK1,NCAM1,TRPC3 |
| 1.278e-03 | -6.66 | amino acid transport | biological process | GO:0006865 | 115 | 22 | 17256 | 1658 |
SERINC5,SLC3A2,SLC6A9,SLC36A1,PPFIA4,SLC36A4,SNAP25,SLC1A3,SLC7A2,APBA1,SLC7A1,SLC7A11,UNC13B,PPFIA2,SH3BP4,SERINC2,SLC7A5,SLC6A15,SLC1A5,STXBP1,SLC16A10,SLC43A1 |
| 1.278e-03 | -6.66 | CATTTCA,MIR-203 | MSigDB lists | CATTTCA,MIR-203 | 273 | 43 | 17377 | 1707 |
BCL11B,SEC24D,GABRB2,XYLT1,GPR180,ADAMTS6,ITPR2,PRKCA,FOXG1,NOVA1,SPIRE1,TRPS1,NUMBL,KMO,SGK3,TSC22D1,PRKG1,NBEA,PRICKLE2,ACVR2A,LIMCH1,AFAP1L2,PDE4D,SEPT3,ETV1,FMNL2,BCL7A,VAV3,CSN2,RAPGEF4,CCNG1,MBNL2,HOXA1,STEAP1,NEGR1,GABARAPL1,IRS2,KLF12,INSIG1,PRKCB,GNAO1,MEF2C,LPP |
| 1.280e-03 | -6.66 | GSE21033_3H_VS_24H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_3H_VS_24H_POLYIC_STIM_DC_UP | 149 | 27 | 17377 | 1707 |
ARHGAP26,EML5,LCA5,MYO10,DNAJC3,ITGA6,DNAJC6,PPFIBP2,PREX1,GTF2IRD1,PDE8A,RNF24,NTRK3,SPATS2L,SLC12A6,ATP1B1,LCP2,SATB1,MBNL2,DOCK2,OTUD1,IKZF3,TGFBR3,TECPR1,GFI1,FMNL2,TBC1D8 |
| 1.280e-03 | -6.66 | GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP | MSigDB lists | GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP | 149 | 27 | 17377 | 1707 |
CXCR5,GCNT2,ACSL1,KCNIP3,AGPAT4,MCTP2,LRRK2,RASA3,CD7,GDPD5,DENND3,IL18R1,BATF3,GPR15,PTPRJ,TMEM154,IGF1R,TM9SF2,ABI3BP,NCOA7,SERINC2,IPCEF1,MAPK10,DOCK8,STOM,CNTN1,B4GALT6 |
| 1.280e-03 | -6.66 | negative regulation of fat cell differentiation | biological process | GO:0045599 | 47 | 12 | 17256 | 1658 |
SMAD3,TRIB3,ENPP1,INSIG1,GATA2,JDP2,C1QL4,WWTR1,GATA3,ZFPM2,ZFP36L2,DDIT3 |
| 1.280e-03 | -6.66 | inorganic ion import across plasma membrane | biological process | GO:0099587 | 47 | 12 | 17256 | 1658 |
TRPM4,SLC39A14,SLC9C1,SLC39A8,STEAP3,ATP1B1,FAM155B,FAM155A,STEAP1,CACNA2D1,SLC9A7,ATP2B4 |
| 1.280e-03 | -6.66 | inorganic cation import across plasma membrane | biological process | GO:0098659 | 47 | 12 | 17256 | 1658 |
TRPM4,SLC39A14,SLC9C1,SLC39A8,STEAP3,ATP1B1,FAM155B,FAM155A,STEAP1,CACNA2D1,SLC9A7,ATP2B4 |
| 1.280e-03 | -6.66 | coronary vasculature development | biological process | GO:0060976 | 47 | 12 | 17256 | 1658 |
TGFBR3,PTK7,APELA,PRICKLE1,ADAMTS6,PRDM1,BMP4,DYNC2H1,NRP1,SMAD6,PDGFRB,PCSK5 |
| 1.282e-03 | -6.66 | GO_PLASMA_MEMBRANE_PROTEIN_COMPLEX | MSigDB lists | GO_PLASMA_MEMBRANE_PROTEIN_COMPLEX | 497 | 70 | 17377 | 1707 |
ACVR1,SORBS1,CACNG3,GRIK2,CHUK,IL13RA1,CACNB4,ABHD6,NOS1AP,TGFBR3,KCNAB1,CHRNA5,ITGB3,KCNS3,ACVR2A,CTTN,PDE4D,SCN2A,HSPA2,SCN3A,KCNB2,ITGB7,TNK2,KCNIP3,ACVR1C,GJB2,PTPN6,SHANK2,CHRNA6,AMIGO1,KCND3,ATP1B1,CD40,GJC1,GNAI1,KCNMB4,KCNG1,ITGA2,BMPR1A,KCNV1,SCN5A,GNG12,ITGA6,FZD8,SCN8A,LRP4,EPS8,RGS7,KCNC4,NEO1,KCNJ4,SCN1B,CACNB2,KCNMB3,LRP6,SYK,KCNQ3,CACNA1E,SNAP25,SNTB1,TLR6,SKAP1,GRIK4,MPP7,GNAO1,GRIN2D,DLG2,CDH2,CACNA2D1,ATP1A3 |
| 1.287e-03 | -6.66 | GO_REGULATION_OF_AXONOGENESIS | MSigDB lists | GO_REGULATION_OF_AXONOGENESIS | 164 | 29 | 17377 | 1707 |
UST,SSH3,BDNF,DISC1,SEMA6B,FN1,ROBO2,BMPR2,FGF13,DCC,LRP4,PLXNA2,NTRK3,AMIGO1,SEMA6A,MAP1B,BCL11A,NKX6-1,RND2,CHN1,SEMA4F,SEMA3C,CTTN,NRP1,SEMA3A,SHOX2,CDH2,SLIT2,SEMA6C |
| 1.289e-03 | -6.65 | ODONNELL_TFRC_TARGETS_UP | MSigDB lists | ODONNELL_TFRC_TARGETS_UP | 371 | 55 | 17377 | 1707 |
PRKAA2,TRIM16L,LGR4,GRIK2,STXBP6,YPEL2,ASS1,GALNT13,IL13RA1,ABAT,LCP2,CD7,SATB1,DYNC1I1,KREMEN1,SEMA6A,SCIN,EIF1,TSC22D1,HS3ST5,PRKG2,SGK1,LRP6,SLC2A12,MPDZ,TOX,NCAM1,NIPAL2,IGSF3,DUSP1,DPYSL5,ALDH2,SESN2,SPOCD1,BTNL9,C3orf52,FHL2,GPSM1,SESN1,DCBLD2,ZNF396,AK1,CD37,PLK2,OSBPL5,INPP4B,MAOA,PTPRS,BBC3,HPGD,ZBTB20,DLX2,THAP10,TTC39A,HOXB9 |
| 1.289e-03 | -6.65 | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_LPS_UP | 371 | 55 | 17377 | 1707 |
ACSL1,REL,ELOVL7,NLRP14,PTPN21,HERC5,BTBD9,MAPK4,SEMA6A,KREMEN1,CTNNA2,FOXP2,PPFIA2,MCF2L,STC2,SRGAP1,MARCKS,DYNC2H1,ARL4D,RNF148,RAPGEF5,SEMA6C,ATP2B1,IGFBP3,FZD1,PNMA2,EPB41L5,TMEM67,CD55,RAB3B,RAB6B,FZD4,RAPGEF2,SOX21,ARID5B,LITAF,WWC1,SLC25A28,FGF17,NT5DC2,CA13,GPLD1,BCL11A,CXCL10,MFSD2A,XBP1,NCOA7,AHNAK2,RCN3,KLF5,HS3ST3B1,SLFN5,COBL,KIF1B,FILIP1 |
| 1.289e-03 | -6.65 | behavior | biological process | GO:0007610 | 543 | 74 | 17256 | 1658 |
PRKN,PDE1B,FGF13,GRIK2,ATP8A1,LDLR,MCOLN3,ABAT,NRXN1,NOVA1,KCNAB1,CHRNA5,ETV1,GATM,NKX2-1,MEIS2,ADM2,FZD4,SHANK2,LRRK2,ADCY1,FGF12,NLGN4X,PRKAR2B,SNCA,PLK2,WFS1,ASIC1,CIART,INPP5F,TMOD2,OXTR,APBA2,MEF2C,CELSR1,PAK5,GABRG2,BTBD9,SLC1A3,P2RY1,APBA1,SELENOP,FOXP2,RNF180,MAP1A,BCHE,AFF2,RASD2,SGK1,FIG4,ZNF385A,HMGCR,BDNF,GPR176,USP2,VLDLR,HOMER2,GRID1,SLITRK5,SDK1,SNAP25,PLCB1,HOXA1,GPR19,ZIC1,DKK1,NEGR1,GPR37,CEBPB,ADGRB3,GNAO1,THBS4,GRIN2D,NPHP1 |
| 1.291e-03 | -6.65 | FBLN2 (fibulin 2) | protein interactions | 2199 | 23 | 8 | 17029 | 1718 |
COL18A1,COL4A5,COL4A3,FN1,BCAN,FBN1,COL4A4,ITGB3 |
| 1.292e-03 | -6.65 | microtubule binding | molecular function | GO:0008017 | 267 | 42 | 17224 | 1680 |
MYO1D,EML5,DNM3,FGF13,KIF5A,MYO1B,KIF5C,HDGFL3,KIF21B,DYNC1I1,MTUS1,FSD1,MAP1A,GAS2L3,REEP1,MYO3B,MYH15,JAKMIP2,JAKMIP3,MYO6,FES,GLI1,DPYSL5,MID2,GAPDH,EML6,DCDC1,MYO10,LRRK2,SYBU,EML1,MAP10,SNCA,MAP1B,MAP2,CCDC181,MAP9,KIF21A,MID1,LZTS1,KIF1B,TPT1 |
| 1.308e-03 | -6.64 | human chr12q12 | chromosome location | human chr12q12 | 30 | 8 | 26185 | 1967 |
NELL2,LRRK2,TMEM117,PRICKLE1,SLC2A13,KIF21A,ALG10B,CNTN1 |
| 1.310e-03 | -6.64 | KLHDC9 (kelch domain containing 9) | protein interactions | 126823 | 6 | 4 | 17029 | 1718 |
DOCK7,THOC3,NT5DC2,CCNA1 |
| 1.310e-03 | -6.64 | METTL7A (methyltransferase like 7A) | protein interactions | 25840 | 6 | 4 | 17029 | 1718 |
RTN1,SLC7A1,TSPAN17,MME |
| 1.313e-03 | -6.64 | GO_SECRETION | MSigDB lists | GO_SECRETION | 566 | 78 | 17377 | 1707 |
DOC2A,PLA2G4A,SCAMP1,PRSS12,AKAP5,SYT12,VAMP8,GATA3,LILRB1,STAT5B,SYT14,NRXN1,LCP2,CANX,DDR1,CACNB4,PCLO,CBLN1,PCDH7,SCIN,UNC13B,PPFIA2,ITGB3,RAB26,SCRN1,LIN7A,STEAP3,PROS1,POU2F2,ARL4D,TLR4,RASGRP1,ABCC4,CSN2,FZD4,WLS,EXOC6B,ACVR2B,RARRES2,TRIM9,ATP7B,ALDOA,PAM,HGF,OXTR,SEPT5,TC2N,PCSK5,TYRO3,SLC6A9,FN1,STXBP5L,SLC1A3,GAS6,APBA1,ARHGAP44,RAB11FIP5,CA2,GATA2,CADPS2,STXBP1,SYK,RIMS2,CHRM3,PCSK6,PAK1,VEGFC,QSOX1,PNP,RAPGEF4,PHACTR2,SNAP25,TLR6,ILDR2,HK2,RAB31,PTPRN2,SNPH |
| 1.314e-03 | -6.63 | GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_UP | 187 | 32 | 17377 | 1707 |
ANO10,STOX2,ROBO2,FBXO4,ASS1,CADM2,GPSM2,NOVA1,TNKS1BP1,MECOM,EFEMP1,ZNF438,ZNF354A,SMTN,NAP1L3,MPDZ,SLCO4C1,FIGN,SLIT2,DZANK1,GPM6A,TMEM43,ANK2,KCNH5,JPH1,WDR25,C1R,TNS1,GPR19,ZIC1,PLOD2,OSBPL5 |
| 1.314e-03 | -6.63 | GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN | MSigDB lists | GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN | 187 | 32 | 17377 | 1707 |
PLA2G4A,DMXL2,CCDC126,GCA,GCNT2,ATF4,SCAMP1,MYO10,LITAF,MSR1,MAFB,C1R,AIG1,GRK6,TGDS,MCOLN2,AHRR,GPR15,FGR,AKAP7,FLRT3,PLXDC2,RAP2A,RAI14,PLEKHG1,COL19A1,P4HA1,SVIL,TMEM37,DYNC2H1,TANC2,SPRY2 |
| 1.314e-03 | -6.63 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP | 187 | 32 | 17377 | 1707 |
AVPI1,LGALS3,RASAL2,RHOBTB1,PFKFB2,MPP1,BACE1,BLVRB,GDPD1,EPS8,DEPTOR,TNFSF13B,SORBS3,CEBPA,TNS1,ATP1B1,FAM13A,PALLD,PLCB1,C11orf45,CHN2,RPS6KA2,CPVL,ADCK1,PRCP,GAS2L3,SRD5A3,HGF,DBP,TNFRSF11A,ATP2B1,MEF2C |
| 1.314e-03 | -6.63 | GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_DN | 187 | 32 | 17377 | 1707 |
MXI1,GAPDH,SEC24D,MPP1,EFNA3,HERC5,ZNF215,SPATS2L,PRKCA,FAM174B,KBTBD11,SLC19A2,GNAI1,SMAD3,EPB41L3,ICA1,CA2,DNAH6,REEP1,MCC,CNNM2,HPGD,TUFT1,SEMA3C,TMOD2,GRB10,FHIT,SPRY4,FBXL2,GFRA1,ATP2B4,CYP1B1 |
| 1.314e-03 | -6.63 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_DN | 187 | 32 | 17377 | 1707 |
LGALS3,CYP4V2,FSTL5,SCIN,FKBP9,TLR3,EOMES,SLC16A2,OPN3,TRIM3,ZNF365,JAM2,TMEM120B,NTNG1,SNAI2,ZNF385A,GCNT2,NECAB1,EML6,ALDH1L2,ACO1,ELMOD1,SATB2,GSTO1,SMPDL3B,GPLD1,PLXDC2,GNB4,CSF1,PAM,ARHGAP28,SH3BGRL2 |
| 1.314e-03 | -6.63 | GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_VS_ACT_WITH_INHIBITOR_PRETREATMENT_IN_MAST_CELL_UP | 187 | 32 | 17377 | 1707 |
PNP,COL4A3,NECAB1,CSN2,IL15,FGF12,RYR2,NPC2,CD40,HERC6,SGK2,OR11H4,INPP1,DACH2,SP8,HECTD2,WARS,ISG20,CXCL10,TLR3,SETDB2,TRIM34,PIK3AP1,TDO2,GNB4,SUSD4,CMPK2,SLFN5,SNX10,TNFRSF11A,FOXA1,PARP9 |
| 1.315e-03 | -6.63 | nucleoside phosphate catabolic process | biological process | GO:1901292 | 108 | 21 | 17256 | 1658 |
NUDT10,GAPDH,PDE1B,PNP,ENO2,PFKFB2,OGDHL,PDE8A,NUDT12,ENPP1,PRTFDC1,PDE10A,ALDOC,ALDOA,HK2,PGM2L1,HK1,PDE4D,ENO1,SMPDL3A,NUDT17 |
| 1.315e-03 | -6.63 | regulation of steroid metabolic process | biological process | GO:0019218 | 108 | 21 | 17256 | 1658 |
FGFR4,MVK,MVD,LDLR,FASN,STAT5B,SCD,BMP6,CYP51A1,IDI1,HMGCS1,INSIG1,STARD4,SREBF1,SQLE,PPARGC1A,DHCR7,GFI1,SNAI2,ABCG1,HMGCR |
| 1.316e-03 | -6.63 | GO_AMINO_ACID_TRANSPORT | MSigDB lists | GO_AMINO_ACID_TRANSPORT | 120 | 23 | 17377 | 1707 |
SERINC5,SLC3A2,SLC6A9,SLC36A1,SLC36A4,SLC7A2,SNAP25,SLC1A3,APBA1,CACNB4,SLC19A2,SLC7A1,UNC13B,SLC7A11,PPFIA2,SLC7A5,SH3BP4,SERINC2,SLC6A15,SLC1A5,STXBP1,SLC16A10,SLC43A1 |
| 1.320e-03 | -6.63 | RAO_BOUND_BY_SALL4 | MSigDB lists | RAO_BOUND_BY_SALL4 | 218 | 36 | 17377 | 1707 |
TFCP2L1,C2orf88,DYRK3,TRIM2,TTC39B,FN1,CFH,TSPAN15,RGS20,ASNS,EOMES,FLRT3,ZIC5,SLCO4C1,JAM2,ETV1,SPRY2,B4GALT6,VEGFC,RAX,GPM6A,GCNT2,RAB38,ZDHHC14,FBXO36,FGFR1,MAP1B,DKK1,SLC39A14,DDAH1,TRIM34,ZNF704,ALG11,SLCO5A1,COBL,PHC1 |
| 1.322e-03 | -6.63 | G-protein mediated events | REACTOME pathways | R-HSA-112040 | 48 | 12 | 10287 | 971 |
PLA2G4A,PDE1B,GNAO1,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PRKCA,PLCB1,PRKACB,GNAI1 |
| 1.325e-03 | -6.63 | KEGG_TGF_BETA_SIGNALING_PATHWAY | MSigDB lists | KEGG_TGF_BETA_SIGNALING_PATHWAY | 85 | 18 | 17377 | 1707 |
ACVR1,ID1,SMAD9,BMPR2,ACVR1C,ACVR2B,BMP6,ZFYVE9,SMAD3,ID3,INHBC,MYC,THBS4,INHBE,ACVR2A,BMP4,BMPR1A,SMAD6 |
| 1.334e-03 | -6.62 | NIELSEN_SCHWANNOMA_DN | MSigDB lists | NIELSEN_SCHWANNOMA_DN | 14 | 6 | 17377 | 1707 |
ASS1,SLC7A2,RBFOX2,GAS1,SNAI2,ADCY1 |
| 1.334e-03 | -6.62 | VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP | MSigDB lists | VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP | 14 | 6 | 17377 | 1707 |
NDUFA4L2,BNIP3,PDK1,ESRP1,STC2,HK2 |
| 1.335e-03 | -6.62 | GO_SYNAPSE_ORGANIZATION | MSigDB lists | GO_SYNAPSE_ORGANIZATION | 142 | 26 | 17377 | 1707 |
BDNF,GPM6A,FARP1,DNM3,PTPRD,LRP4,SHANK2,LRRK2,NFIA,NLGN4X,COL4A5,SDK1,NRXN1,CACNB4,DNER,PCLO,NEDD4,SNCA,PCDHB14,UNC13B,FLRT3,CACNB2,CDH2,MAGI2,CTNND2,FZD1 |
| 1.337e-03 | -6.62 | regulation of programmed cell death | biological process | GO:0043067 | 1583 | 187 | 17256 | 1658 |
TRIM2,ACVR1,GRIK2,DNAJC3,TNFAIP8L2,LILRB1,GATA3,NPM1,STAT5B,PRKCA,AARS,EYA4,STK24,F3,TXNDC5,GSDME,BAG3,RPS6KA2,PMAIP1,HRK,CTTN,EPHB6,FANK1,ENO1,SLIT2,POU3F3,PDGFRB,LAMP3,CYP1B1,ATF4,COL4A3,ACVR1C,LRRK2,BNIP3L,DEPTOR,YAP1,AGO4,ROR1,SGK2,SAV1,ARHGEF26,INHBC,GSN,SH3RF1,NCKAP1L,RASGRF2,PLK2,TNFRSF1A,BBC3,ERCC5,NRP1,UNC5B,PPARGC1A,MEF2C,BCL11B,PRKAA2,TYRO3,LATS2,LGALS3,GABRB2,ITGA6,SLK,DHCR24,SLC25A27,TNFRSF10C,GAS1,MECOM,SYCP2,BNIP1,IGF1R,GATA2,MYC,PRELID1,LRP6,BNIP3,STXBP1,ZNF385A,NOS3,HMGCR,PAK1,FGFR4,RPL26,UNC5C,BDNF,ATP5IF1,MSTN,FHL2,OBSCN,STRADB,HIP1,FAM162A,HERPUD1,INHBE,SFN,EPHA3,PRKN,BTC,ID1,COL18A1,NTRK3,DDR1,TIAM2,SCIN,TLR3,ASNS,UNC13B,MAGEA3,BCL6,DAB2IP,STEAP3,MET,PERP,SNAI2,DOCK8,CTH,IGFBP3,PRAME,GAPDH,NOP53,NKX3-2,PREX1,PRKCQ,WNT11,ATF3,ATOH1,CD40,FGFR1,SNCA,IRS2,SMAD3,IKZF3,BEX3,WFS1,MAP3K21,HPGD,TNFSF15,HGF,BMPR1A,ATG5,RETREG1,TNIK,DYRK3,ARHGEF11,PAK5,APBB1,BIK,GAS6,EPHB1,TPD52L1,BMP6,BEX2,MCF2L,PRKCD,TFAP2A,SGK3,SGK1,YBX3,SMAD6,TNFRSF11A,SPRY2,PNMA2,DUSP1,SLC40A1,VAV3,CARD6,MSX1,RAPGEF2,NUGGC,NUAK2,AGAP2,RACK1,MGMT,GPLD1,DKK1,CEBPB,ID3,NACC2,TERT,ACER2,MAP2K6,XBP1,PCGF2,BMP4,MAP3K20,DDIT3,FOXA1,TPT1 |
| 1.344e-03 | -6.61 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | 172 | 30 | 17377 | 1707 |
MAN2B2,VAV3,BMPR2,ITPRIP,ATP8A1,UBASH3B,RAPGEF2,ITGA6,ABHD13,PLEKHA1,HERC6,EXOG,MTUS1,HEG1,NAP1L5,IRS2,ARHGAP21,NSD1,BACH2,MPP7,PELI2,WDR19,TSC22D1,SGK1,FHIT,IPCEF1,DNAH5,BTRC,DUSP1,PCSK5 |
| 1.344e-03 | -6.61 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_DN | 172 | 30 | 17377 | 1707 |
SUSD3,SMAD9,RAPGEF2,C3orf52,JPH1,ARID5B,TNFSF13B,SELL,GSTO1,ATP1B1,LACC1,SNX9,PGAP1,ATXN7L1,ARHGAP21,TIFA,GBP1,PELI2,GPR155,CHRDL1,PLEKHG1,SP140,ALPK1,RRAS2,MAST4,TRPC3,MLLT3,CRISPLD1,PARP9,LAMP3 |
| 1.351e-03 | -6.61 | GO_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | 29 | 9 | 17377 | 1707 |
MAPKAPK2,FN1,NR4A1,XBP1,ERN1,DAB2IP,NRP1,GAS1,PDGFRB |
| 1.351e-03 | -6.61 | GO_REGULATION_OF_PLATELET_ACTIVATION | MSigDB lists | GO_REGULATION_OF_PLATELET_ACTIVATION | 29 | 9 | 17377 | 1707 |
PRKCQ,ABAT,PRKCA,TLR4,SYK,UBASH3B,PRKCD,NOS3,PRKG1 |
| 1.352e-03 | -6.61 | GSE29949_MICROGLIA_VS_DC_BRAIN_UP | MSigDB lists | GSE29949_MICROGLIA_VS_DC_BRAIN_UP | 195 | 33 | 17377 | 1707 |
CXCR5,RGS16,TNK2,ACSL1,DYRK3,BMPR2,WISP3,NR4A1,REL,ANK2,PTPN21,WWC1,COL18A1,COBLL1,GSTO1,ATF3,ATP1B1,LCP2,DDIT4,CA2,CPVL,MYC,EIF1,SLC7A5,LAPTM4B,BBC3,GRB10,EPHB6,GEM,ZNF460,SHOX2,VGLL4,IL1RAP |
| 1.352e-03 | -6.61 | HALLMARK_P53_PATHWAY | MSigDB lists | HALLMARK_P53_PATHWAY | 195 | 33 | 17377 | 1707 |
RGS16,FGF13,ST14,VAMP8,CEBPA,ABAT,ABHD4,TPD52L1,SLC19A2,DDIT4,SLC7A11,TSC22D1,STEAP3,VWA5A,PTPRE,ZNF365,PERP,SLC3A2,TGFA,LRMP,ATF3,CCNG1,SESN1,FAM162A,BAIAP2,TRIB3,AK1,PLK2,ERCC5,RPS12,DDIT3,SFN,STOM |
| 1.352e-03 | -6.61 | GSE14350_IL2RB_KO_VS_WT_TREG_DN | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TREG_DN | 195 | 33 | 17377 | 1707 |
ZNF516,LGALS3,CKAP2,PSTPIP2,YPEL2,GTF2IRD1,NDRG2,ADAMTS6,CHSY1,ABHD4,IKZF2,EPCAM,GPR15,NAP1L3,TRPM4,RHOQ,WLS,GSTO1,PRDM1,TTC28,SESN1,MAGI3,ARHGAP21,TIFA,PTPRJ,ICA1,TMEM237,SH3RF1,PLXDC2,PELI2,TMEFF2,CSRP2,RRAGD |
| 1.352e-03 | -6.61 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | 195 | 33 | 17377 | 1707 |
TRIM2,FN1,KLHL13,GPR65,GALNT6,ITGA6,C20orf194,IGF2BP2,FAM198B,P2RY1,GAS6,PFN2,DOCK2,MCOLN2,RNF150,TACC2,PRKG1,DAB2IP,ESD,ANTXR2,GPR176,ARAP2,TES,SHISA2,CD40,MFSD6,PRKCB,PTPRS,SFMBT1,NRP1,STON2,LPP,ATP1A3 |
| 1.353e-03 | -6.61 | TIEN_INTESTINE_PROBIOTICS_6HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_6HR_DN | 157 | 28 | 17377 | 1707 |
DBN1,RIN2,MICAL2,ZNF395,CRIM1,PLEKHA5,RBFOX2,RAPGEF2,CAP2,FHL2,FERMT2,TJP1,COTL1,PLCB1,STEAP1,SLC19A2,FKBP11,TTC1,WWTR1,TSC22D1,SGK1,INPP5F,WWC2,SMPDL3A,CKAP4,CEBPD,DOCK9,GAB2 |
| 1.353e-03 | -6.61 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN | 157 | 28 | 17377 | 1707 |
TFCP2L1,BTNL9,GJB2,FZD8,DNAJC6,MCOLN3,ASS1,CR2,DOCK5,DNER,TPD52L1,COL27A1,MAP1B,TGFBR3,BACH2,ABI3BP,MAP2,ABCA5,PRKCB,MPP7,MAGEA3,AHNAK2,SLC6A15,PROS1,ST8SIA1,MAGEA6,DCBLD1,ACSM3 |
| 1.357e-03 | -6.60 | endothelial cell morphogenesis | biological process | GO:0001886 | 10 | 5 | 17256 | 1658 |
COL18A1,ID1,MET,ARHGEF26,HEG1 |
| 1.357e-03 | -6.60 | muscle atrophy | biological process | GO:0014889 | 10 | 5 | 17256 | 1658 |
GSN,PPARGC1A,IL15,MSTN,GATM |
| 1.357e-03 | -6.60 | mitral valve morphogenesis | biological process | GO:0003183 | 10 | 5 | 17256 | 1658 |
BMPR1A,ACVR1,BMPR2,SMAD6,DCHS1 |
| 1.357e-03 | -6.60 | actin filament network formation | biological process | GO:0051639 | 10 | 5 | 17256 | 1658 |
COBLL1,PLS1,COBL,FHOD3,PLS3 |
| 1.358e-03 | -6.60 | positive regulation of osteoblast differentiation | biological process | GO:0045669 | 60 | 14 | 17256 | 1658 |
PDLIM7,CEBPB,RUNX2,ACVR1,BMPR2,ZHX3,ACVR2A,HGF,CEBPA,BMPR1A,BMP4,ACVR2B,BMP6,MEF2C |
| 1.358e-03 | -6.60 | purine nucleoside diphosphate metabolic process | biological process | GO:0009135 | 60 | 14 | 17256 | 1658 |
GAPDH,ENO2,PFKFB2,MPP1,ALDOC,ALDOA,MPP2,OGDHL,HK2,PGM2L1,DLG2,HK1,ENO1,MAGI3 |
| 1.358e-03 | -6.60 | purine ribonucleoside diphosphate metabolic process | biological process | GO:0009179 | 60 | 14 | 17256 | 1658 |
GAPDH,ENO2,PFKFB2,MPP1,ALDOC,ALDOA,MPP2,OGDHL,HK2,PGM2L1,DLG2,HK1,ENO1,MAGI3 |
| 1.360e-03 | -6.60 | regulation of neurotransmitter transport | biological process | GO:0051588 | 94 | 19 | 17256 | 1658 |
PRKN,RAB3B,SYT12,VAMP8,LRRK2,LILRB1,ABAT,KCNC4,PFN2,PPP1R9A,SNCA,KCNMB4,UNC13B,KMO,ASIC1,SEPT5,STXBP1,RIMS2,MEF2C |
| 1.362e-03 | -6.60 | LABBE_TGFB1_TARGETS_UP | MSigDB lists | LABBE_TGFB1_TARGETS_UP | 99 | 20 | 17377 | 1707 |
HBG2,AASS,GRIK2,KIF5A,JPH1,LITAF,ASS1,ADD2,VIM,ITPR2,ADSSL1,BEX2,AK1,UNC13B,AADAT,TSC22D1,BMP1,SGK1,CPE,ABCG1 |
| 1.362e-03 | -6.60 | roof of mouth development | biological process | GO:0060021 | 87 | 18 | 17256 | 1658 |
MSX1,ARID5B,SATB2,WNT11,PLEKHA1,ACVR2B,ASPH,SKI,MSC,TGFBR3,INSIG1,DLX6,FRAS1,TFAP2A,LRP6,BMPR1A,MEF2C,FZD1 |
| 1.367e-03 | -6.60 | WW_DOMAIN_2 | prosite domains | PS50020 | 49 | 13 | 12060 | 1278 |
BAG3,PLEKHA5,APBB1,WWTR1,HECW2,YAP1,WWC1,WWC2,TCERG1L,SAV1,MAGI2,MAGI3,NEDD4 |
| 1.370e-03 | -6.59 | Rho guanyl-nucleotide exchange factor activity | molecular function | GO:0005089 | 79 | 17 | 17224 | 1680 |
VAV3,FARP1,ARHGEF28,ARHGEF11,DOCK1,MCF2L2,EPS8,PREX1,SPATA13,OBSCN,DOCK2,ARHGEF26,TIAM2,ARHGEF10L,MCF2L,RASGRF2,PLEKHG1 |
| 1.371e-03 | -6.59 | KOYAMA_SEMA3B_TARGETS_DN | MSigDB lists | KOYAMA_SEMA3B_TARGETS_DN | 372 | 55 | 17377 | 1707 |
CGN,NMNAT3,NECAB2,CELSR1,C1QTNF3,FN1,RASAL2,CHCHD7,RIMKLA,LRRCC1,RGS20,BTBD9,NOVA1,PGAP1,SYDE2,PPM1E,FBXO32,HMGCS1,GATA2,LHX6,LRP6,GSTM3,FAM133A,SYNGR3,NIPAL2,SMAD6,ATP2B1,ATL1,RPL26,MYO10,GSTM4,ARID5B,SMARCD3,PRKAR2B,ROR1,CD40,ZDHHC14,CPEB1,DKK1,DPY19L2,TCF7L1,INSIG1,PMEPA1,TERT,CCDC146,KCNG1,SH3BP4,ZNF704,SVIL,EGFL7,SEMA3C,TPM1,NR3C2,LARP1,LPP |
| 1.371e-03 | -6.59 | GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 991 | 126 | 17377 | 1707 |
NEK10,ACVR1,AVPI1,ACSL1,FGF13,IL15,AKAP5,GPR65,NTRK3,LCP2,PRKCA,SNX9,PIBF1,PPP1R9A,TLR3,ITGB3,RAP2A,ACVR2A,DAB2IP,MARCKS,TLR4,TSHR,HSPA2,RASGRP1,PRKACB,PDGFRB,IGFBP3,FZD1,TNK2,GCNT2,PFKFB2,FZD4,CAP2,TGFA,LRRK2,ADCY1,PRKAR2B,WNT11,ACVR2B,RARRES2,CD40,FGFR1,SNCA,SMAD3,INHBC,CXCL10,NRG3,GPRC5B,NCKAP1L,WFS1,ITGA2,ERN1,TNFRSF1A,DUSP19,ADRB1,BMP1,TNFSF15,GRB10,DIRAS1,HGF,BMPR1A,NRP1,PPARGC1A,MAPK10,MAGI2,MID1,CNTN1,MEF2C,PRKAA2,TNIK,BMPR2,EDA2R,ITGA6,FZD8,LRP4,SORBS3,GAS6,P2RY1,PKN1,TNFRSF19,PFN2,TPD52L1,BMP6,PRKCD,GHR,ADCY6,AFAP1L2,IQGAP3,TNFRSF11A,SPRY2,SYK,GPR161,HMGCR,NOS3,FGFR4,VEGFC,PAK1,MOB1B,VAV3,MSTN,RAPGEF2,VLDLR,DUSP9,CALCRL,WWC1,STRADB,GUCY1A2,TLR6,PLCB1,GPLD1,GPR37,MAPKAPK2,PTPRC,FGR,DOCK7,PELI2,MAP2K6,THBS4,CSF1,XBP1,INHBE,LRRK1,BMP4,CDH2,SMYD3,ATP2B4 |
| 1.371e-03 | -6.59 | GO_POSITIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | 991 | 126 | 17377 | 1707 |
NEK10,ACVR1,AVPI1,ACSL1,FGF13,IL15,AKAP5,GPR65,NTRK3,LCP2,PRKCA,PIBF1,SNX9,PPP1R9A,TLR3,ITGB3,RAP2A,ACVR2A,DAB2IP,MARCKS,TLR4,TSHR,HSPA2,RASGRP1,PRKACB,PDGFRB,IGFBP3,FZD1,TNK2,GCNT2,FZD4,PFKFB2,TGFA,CAP2,LRRK2,ADCY1,PRKAR2B,WNT11,ACVR2B,RARRES2,CD40,FGFR1,SNCA,SMAD3,INHBC,CXCL10,NRG3,GPRC5B,NCKAP1L,WFS1,ITGA2,ERN1,TNFRSF1A,DUSP19,BMP1,ADRB1,GRB10,TNFSF15,DIRAS1,HGF,BMPR1A,PPARGC1A,NRP1,MAPK10,MAGI2,MID1,CNTN1,MEF2C,PRKAA2,TNIK,EDA2R,BMPR2,ITGA6,FZD8,LRP4,SORBS3,P2RY1,GAS6,PKN1,PFN2,TNFRSF19,TPD52L1,BMP6,GHR,PRKCD,ADCY6,AFAP1L2,IQGAP3,TNFRSF11A,SPRY2,SYK,GPR161,NOS3,HMGCR,MOB1B,FGFR4,PAK1,VEGFC,VAV3,MSTN,RAPGEF2,VLDLR,DUSP9,WWC1,CALCRL,STRADB,GUCY1A2,PLCB1,TLR6,GPLD1,GPR37,MAPKAPK2,PTPRC,FGR,DOCK7,MAP2K6,CSF1,THBS4,PELI2,XBP1,INHBE,BMP4,LRRK1,CDH2,SMYD3,ATP2B4 |
| 1.372e-03 | -6.59 | Ras GTPase binding | molecular function | GO:0017016 | 519 | 72 | 17224 | 1680 |
EXPH5,DMXL2,BTC,DOCK1,DENND3,DOCK2,TBC1D30,TIAM2,ARHGEF10L,ADPRHL1,UNC13B,RTKN2,MET,MYRIP,RAPGEF5,RASGRP1,PDGFRB,TBC1D8,LRRK2,PREX1,FGF17,TBC1D16,SERGEF,FGFR1,ARHGEF26,IRS2,RANBP2,RASGRF2,PLEKHG1,ADRB1,HGF,HACE1,DENND5B,FARP1,STXBP5L,ARHGEF11,PAK5,TBC1D1,STXBP6,RUSC2,IPO5,EPS8,PKN1,ARHGAP44,RAB11FIP5,MCF2L,SRGAP1,IQGAP3,TBC1D9,NCAM1,YBX3,DENND1C,FMNL2,GFRA1,RIMS2,FGFR4,PAK1,VAV3,RIN2,ARHGEF28,TBC1D8B,RAPGEF2,MCF2L2,RAPGEF4,SPATA13,OBSCN,TBC1D2,DOCK7,PKN3,SH3BP4,GRIN2D,TBC1D4 |
| 1.377e-03 | -6.59 | embryonic organ morphogenesis | biological process | GO:0048562 | 280 | 43 | 17256 | 1658 |
ACVR1,RUNX2,CELSR1,OTX1,GATA3,OVOL2,FOXG1,EFEMP1,IRX5,SETDB2,PDZD7,GATA2,DLX6,TFAP2A,MYO3B,LRP6,SPRY2,GLI1,MICAL2,MSX1,NKX3-2,MAFB,YAP1,RYR2,WNT11,SATB2,ATOH1,HOXA1,FGFR1,ZIC1,SMAD3,INSIG1,FBN1,PTK7,RBPMS2,WDR19,PCGF2,BMP4,DLX2,SHOX2,MMP16,SIX2,MEF2C |
| 1.383e-03 | -6.58 | muscle structure development | biological process | GO:0061061 | 466 | 65 | 17256 | 1658 |
ACVR1,ASS1,PKP2,CHUK,DNER,SKI,SPEG,TGFBR3,EOMES,KCNAB1,COL19A1,MYH15,ETV1,NEB,PDGFRB,FZD1,MYLK3,ANK2,JPH1,MEF2B,CBY1,ATF3,DSP,DYRK1B,MSC,CXCL10,HLF,POPDC3,KLF5,TMOD2,BMPR1A,DISP1,ATG5,TPM1,HEY1,MEF2C,BVES,FHOD3,MYORG,FOXP2,EEF2,SMTN,HMGCR,USP2,MSX1,MSTN,ARID5B,FHL2,OBSCN,RYR2,SMARCD3,ZFPM2,MKX,HEG1,ID3,RIPOR2,ADGRB3,HEYL,XBP1,SVIL,MYOM2,BMP4,SHOX2,CDH2,SMYD3 |
| 1.384e-03 | -6.58 | cell cortex part | cellular component | GO:0044448 | 163 | 28 | 18223 | 1724 |
DBN1,PHLDB2,MPP1,STXBP6,CAP2,EXOC6B,DSTN,HIP1,PLS1,GPSM2,ASPH,PCLO,PPP1R9A,GNAI1,GSN,PLEKHH2,MYADM,GYPC,UNC13B,WIPF3,RTKN2,CTTN,SEPT5,SEPT3,MYRIP,ENO1,CDH2,RIMS2 |
| 1.385e-03 | -6.58 | transcription regulatory region sequence-specific DNA binding | molecular function | GO:0000976 | 738 | 97 | 17224 | 1680 |
CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,ZNF93,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 |
| 1.387e-03 | -6.58 | regulation of transferase activity | biological process | GO:0051338 | 995 | 124 | 17256 | 1658 |
EPHA3,PRKN,NEK10,ACSL1,AVPI1,FGF13,DUSP8,DNAJC3,NPM1,CEBPA,NTRK3,LCP2,SNX9,PIBF1,DDR1,PPP1R9A,STK24,PPM1E,TLR3,CDC14B,ZFYVE28,ITGB3,SERINC2,DAB2IP,EPHB6,MET,TLR4,PRKACB,RASGRP1,PDGFRB,SESN2,FZD4,PFKFB2,PTPN6,TGFA,LRRK2,PREX1,ADCY1,DEPTOR,PRKAR2B,WNT11,PRKCQ,ACVR2B,ROR1,CD40,FGFR1,SNCA,WARS,CAMK2N1,IRS2,CXCL10,NRG3,PTPRJ,GPRC5B,NCKAP1L,ERN1,WWTR1,MAP3K21,DUSP19,TNFSF15,HGF,DIRAS1,SPRY4,MAPK10,CACUL1,TENM1,TYRO3,LATS2,SERINC5,TNIK,PAK5,SLK,FZD8,UBASH3B,IPO5,HERC5,GAS6,PKN1,EPHB1,TPD52L1,IGF1R,MYC,FLRT3,PRKCD,GHR,LRP6,ADCY6,INAVA,AFAP1L2,IQGAP3,ERRFI1,TNFRSF11A,SYK,SPRY2,HMGCR,DUSP1,PAK1,FGFR4,VAV3,MSTN,RAPGEF2,VLDLR,DUSP9,STRADB,AGAP2,CCNG1,RACK1,ARRDC4,TLR6,DKK1,MAPKAPK2,PTPRC,TRIB3,FGR,MAP2K6,CSF1,BMP4,CERS1,SMYD3,MAP3K20,TESC,ATP2B4,SFN,PKIA |
| 1.394e-03 | -6.58 | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_DN | 180 | 31 | 17377 | 1707 |
CARS,MXI1,ATF4,GALNT6,TES,PKP2,ATF3,CHAC1,NDFIP2,AARS,HERPUD1,CD53,ZFP62,TRIB3,ASNS,MYC,MCF2L,STC2,PRELID2,RUNDC3B,HK2,P4HA1,FAM84B,GEM,ERRFI1,TSPAN9,MLLT3,SMYD3,RASGRP1,LRP12,DDIT3 |
| 1.394e-03 | -6.58 | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | 180 | 31 | 17377 | 1707 |
RWDD2A,ANTXR2,SYNPO2,ALDH2,ABCC4,RAB6B,LRP4,TNFAIP8L2,DEPTOR,FAM102B,ITPR2,LACC1,ABHD4,TTC30B,EYA4,RERE,RASSF8,EPB41L3,CD37,SIPA1L2,TIFA,TLR3,NACC2,APLF,CAB39L,FIG4,WWC2,LRRC27,PURG,SMPDL3A,SLC16A10 |
| 1.399e-03 | -6.57 | WW | smart domains | SM00456 | 47 | 13 | 9493 | 1056 |
BAG3,PLEKHA5,APBB1,WWTR1,HECW2,YAP1,WWC1,WWC2,TCERG1L,SAV1,MAGI2,MAGI3,NEDD4 |
| 1.403e-03 | -6.57 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | molecular function | GO:0001228 | 417 | 60 | 17224 | 1680 |
CREB3L2,BCL11B,RUNX2,PLAG1,REL,OTX1,GATA3,STAT5B,CEBPA,OVOL2,TRPS1,GRHL1,GATA2,MYC,BHLHA15,SREBF1,EBF4,TFAP2A,POU2F2,ETV1,GLIS1,BARX1,CEBPD,RAX,ATF4,MEIS2,MSX1,HNF4G,NR6A1,SOX21,ESRRG,NR4A1,NFIA,LITAF,NFE2L1,MAFB,MEF2B,ATF3,SATB2,ATOH1,BATF,HOXA1,ZIC1,EBF1,CEBPB,IKZF3,HLF,PLAGL1,HEYL,SOHLH2,KLF5,HOXD13,DLX2,DBP,PAX9,NKX2-8,SIX2,DDIT3,FOXA1,MEF2C |
| 1.409e-03 | -6.56 | GO_POSITIVE_REGULATION_OF_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSPORT | 893 | 115 | 17377 | 1707 |
EXPH5,PLA2G4A,SORBS1,TRIM16,AKAP5,ATP8A1,C4A,VAMP8,GATA3,PKP2,ABAT,DOCK2,NCS1,NOS1AP,SCIN,TLR3,UNC13B,SEC16B,AKAP7,PMAIP1,DACT1,CNKSR3,TRPC1,MARCKS,PROS1,SYNGR3,RAB27B,PLTP,TLR4,MYRIP,HSPA2,RASGRP1,PDGFRB,GAB2,PFKFB2,WLS,ANK2,FGF12,ELMOD1,PRKCQ,GSTO1,SYNJ2BP,RARRES2,AMIGO1,ATP1B1,SGK2,ASPH,SNCA,SMAD3,IRS2,CXCL10,NCKAP1L,PEMT,WFS1,ITGA2,BBC3,OXTR,BMPR1A,ATG5,SEPT5,TNFSF4,MAGI2,CNTN1,SCN5A,C1QTNF3,LGALS3,STXBP5L,CD276,APBB1,IPO5,P2RY1,GAS6,MLC1,IL18R1,BMP6,NEDD4,MCU,NKX6-1,CA2,GATA2,SCN1B,CACNB2,PRKCD,SGK3,PRELID1,SGK1,LMAN2,CADPS2,STXBP1,TNFRSF11A,SYK,TRPM4,VEGFC,RAB3B,GSTM2,RHOQ,HIP1,RYR2,PLCB1,LRAT,GPLD1,ZIC1,FGR,RPL28,MAP2K6,XBP1,BMP4,CDH2,TRPC3,TESC,IL9R,SFN,CACNA2D1,STOM,ABCG1 |
| 1.412e-03 | -6.56 | YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP | MSigDB lists | YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP | 72 | 16 | 17377 | 1707 |
NBL1,ID1,NR4A1,CRIP2,NDRG2,RARRES2,GAS6,LEPR,KCNAB1,PROS1,DBP,KLF9,NCAM1,GEM,HMGCR,IGFBP3 |
| 1.418e-03 | -6.56 | GO_PALLIUM_DEVELOPMENT | MSigDB lists | GO_PALLIUM_DEVELOPMENT | 150 | 27 | 17377 | 1707 |
GNG12,DISC1,FGF13,AKAP5,VLDLR,EFHC1,ATOH1,BCAN,PLCB1,FGFR1,FOXP2,FAT4,EOMES,TACC2,LHX6,LAMB1,LRP6,PTPRS,DAB2IP,DLX2,NRP1,SEMA3A,CDH2,SLIT2,ATP2B4,POU3F3,NKX2-1 |
| 1.418e-03 | -6.56 | IL15_UP.V1_DN | MSigDB lists | IL15_UP.V1_DN | 165 | 29 | 17377 | 1707 |
RIN2,CACNG3,PRSS16,LGR4,PNRC1,CLGN,AKAP5,RHOBTB1,RAB6B,CACNA1E,ATP8A1,CYB5R2,EPS8,LRMP,DEPTOR,DOCK3,KCNC4,SESN1,TBC1D2,MAP2K6,DACT1,PRKG1,HOXD13,GEM,TANC2,TNFRSF11A,SNAI2,SCN3A,CNTN1 |
| 1.419e-03 | -6.56 | phosphatidylinositol 3-kinase binding | molecular function | GO:0043548 | 24 | 8 | 17224 | 1680 |
TYRO3,IRS2,DAB2IP,FBXL2,IGF1R,PIK3AP1,PTPN13,RASD2 |
| 1.435e-03 | -6.55 | phosphoric ester hydrolase activity | molecular function | GO:0042578 | 367 | 54 | 17224 | 1680 |
INPPL1,PDE1B,DUSP8,PTPRD,UBASH3B,PTPN21,NOTUM,LPIN3,GDPD5,INPP1,PGAP1,EYA4,PPM1E,PLPP1,CDC14B,PDE10A,PALD1,FIG4,PDE4D,PPP2R2B,PTPRE,SMPDL3A,CHRM3,DUSP1,PFKFB4,PPP1R3D,SSH3,PTPRU,PFKFB2,PTPN13,PTPN6,GDPD1,DNAJC6,PLPP2,DUSP9,PDE8A,LHPP,PXYLP1,PLCB1,NT5DC2,SMPDL3B,GPLD1,PTPRC,ENPP1,PTPRJ,PLPPR2,ENPP6,INPP4B,DUSP19,PTPRS,PTPRN2,INPP5F,PLD1,PSPH |
| 1.438e-03 | -6.54 | GSE3982_MAST_CELL_VS_BCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_BCELL_UP | 188 | 32 | 17377 | 1707 |
PPP1R3D,SORBS1,ELOVL4,ABCC4,SLC27A2,RHOBTB1,DHCR24,EFHC2,DEPTOR,SMARCD3,PHACTR2,COL14A1,ABHD6,LEPR,QPRT,GABARAPL1,GSN,SLC30A4,BACE2,P4HA2,HK2,TSC22D1,BMP1,RGS10,LAPTM4B,GRB10,IPCEF1,CTTN,NEUROG2,SPRY2,SMYD3,LRP12 |
| 1.438e-03 | -6.54 | GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_UP | MSigDB lists | GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_UP | 188 | 32 | 17377 | 1707 |
PTCH2,FRMPD3,PRKAA2,INTU,C2orf88,MYO1D,DNM3,ACVR1,PLAG1,BACE1,FERMT2,ADD2,NPM1,IL13RA1,ZFPM2,PCLO,FSTL5,SLC35F1,EPCAM,TUBB4A,TGFBR3,PCDHB7,RNF217,ITGBL1,BACE2,ATP7B,JAKMIP2,BMPR1A,TSHR,RNF122,MYT1,PGBD5 |
| 1.438e-03 | -6.54 | GSE20715_0H_VS_24H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_LUNG_UP | 188 | 32 | 17377 | 1707 |
EPB41L5,SLC40A1,ARAP2,EVL,MPP1,CYTH3,PPFIBP2,TCEA3,FHDC1,SELL,PKP2,RASA3,RHPN2,PRDM1,FAM198B,CD7,SATB1,BEX2,PPP2R3A,CD53,PTPRC,RTN1,CA2,BACH2,PRKCB,GNB4,RASGRF2,ADRB1,PTPRS,TSPAN13,FIG4,BTRC |
| 1.438e-03 | -6.54 | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_DN | 188 | 32 | 17377 | 1707 |
EML5,ID1,EPS8,FHDC1,STAT5B,PHGDH,DDR1,PRRG4,PPP2R3A,FKBP11,SYDE2,F3,RND2,ATXN7L1,EPCAM,IGF1R,ZDHHC23,KIAA1211,TMC7,GARS,TMEM65,LRMP,TNS1,DSP,C9orf116,TRIB3,EIF4EBP1,PTPRS,KIAA0513,NRP1,DISP2,PSPH |
| 1.438e-03 | -6.54 | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | 188 | 32 | 17377 | 1707 |
CARD6,PNRC1,TES,FOXN3,TMTC4,TNFSF13B,BNIP3L,ASS1,RNF125,SLC36A4,FAM117B,SCD,SFXN3,KIF21B,SESN1,NEDD4,BATF3,ENTPD1,CXCL10,ZNF362,IGF1R,AKT3,EHD3,RGS10,INPP5F,DBP,ST8SIA1,RCAN3,PCK2,NRP1,GFI1,SLC16A10 |
| 1.442e-03 | -6.54 | inorganic molecular entity transmembrane transporter activity | molecular function | GO:0015318 | 855 | 110 | 17224 | 1680 |
CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC19A2,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,SLC22A17,SLC16A2,SLC22A18,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,ABCC4,LRRC8B,SLC9C1,SLC39A8,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,ABCC2,KCND3,ATP1B1,GJC1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,TMEM63C,SERINC5,SCN5A,SLC6A9,GABRB2,SCN8A,ATP6V1E2,GABRG2,SLC36A4,GAS6,GABRR2,SLC1A3,SLC12A6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SLC7A11,SCN1B,CACNB2,KCNMB3,SLC16A9,SLC6A15,NIPAL2,FAM155A,SLC45A3,ATP2B1,TRPM4,NDUFA4L2,SLC40A1,SLC37A1,KCNQ3,SLC27A2,SLC36A1,CACNA1E,GRID1,RYR2,TTYH2,RASA3,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,SLC7A5,GRIN2D,SLC1A5,TRPC3,SLC16A10,CACNA2D1,ATP2B4,ABCG1,ATP1A3,SLC43A1 |
| 1.443e-03 | -6.54 | MGAT4C (MGAT4 family member C) | protein interactions | 25834 | 34 | 10 | 17029 | 1718 |
CHSY3,GXYLT2,PCSK1N,CNTNAP3,GALNT12,FRAS1,LDLR,ITGA2,LRP6,B4GALT6 |
| 1.453e-03 | -6.53 | profilin binding | molecular function | GO:0005522 | 10 | 5 | 17224 | 1680 |
DBN1,RHOQ,CTTN,EVL,PCLO |
| 1.453e-03 | -6.53 | WASL (Wiskott-Aldrich syndrome like) | protein interactions | 8976 | 64 | 15 | 17029 | 1718 |
WASF3,GSN,RHOQ,ZNF395,BCHE,WIPF3,APBB1,IPO5,PACSIN3,SORBS3,CTTN,PACSIN1,FNBP1L,SNX9,BAIAP2 |
| 1.456e-03 | -6.53 | SAM/pointed_sf | interpro domains | IPR013761 | 114 | 22 | 18492 | 1811 |
EPHA3,TFCP2L1,ARAP2,INPPL1,SHANK2,PPFIBP2,PPFIA4,GAREM1,LCP2,EPHB1,PPP1R9A,L3MBTL4,PPFIBP1,KAZN,PPFIA2,CNKSR3,SAMD11,SFMBT1,EPHB6,SAMD13,MAP3K20,PHC1 |
| 1.459e-03 | -6.53 | GO_POSITIVE_REGULATION_OF_LOCOMOTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_LOCOMOTION | 398 | 58 | 17377 | 1707 |
SEMA6B,AMOTL1,ACVR1,LGALS3,FN1,BMPR2,BVES,RHOD,ATP8A1,GATA3,COL18A1,NTRK3,GAS6,PRKCA,SEMA6A,F3,EPCAM,SEMA4F,IGF1R,ITGB3,DAB2IP,MET,RRAS2,SLIT2,SEMA6C,SNAI2,PDGFRB,GLI1,VEGFC,PAK1,EPB41L5,FER,GCNT2,RAPGEF2,WNT11,RARRES2,DOCK5,FGFR1,CPEB1,GPLD1,SMAD3,PTPRC,IRS2,CXCL10,FGR,DOCK7,MYADM,NCKAP1L,CCBE1,THBS4,CSF1,ITGA2,LAMB1,SEMA3C,HGF,BMP4,NRP1,SEMA3A |
| 1.465e-03 | -6.53 | abdomen | COSMIC cancer mutations | abdomen | 615 | 83 | 17385 | 1698 |
BTC,CFH,RECK,LPCAT2,LDLR,PTPN21,MCOLN3,STAT5B,CTBP2,ITPR2,SEMA6A,ZFYVE9,NELL2,KMO,CNKSR3,ALDH1L1,MET,PTPRE,DNAH5,SCN3A,DPP10,FER,ABCC4,DCC,EXOC6B,ANK2,MEF2B,TNS1,DSP,TMEM132B,ARMC4,PTPRJ,POPDC3,ITGBL1,PTK7,WWTR1,PTPRS,STON2,CTNND2,PCDH18,SCN5A,WDR17,IL32,FN1,ROBO2,PTPRD,GTF2IRD1,GABRG2,EPHB1,SPINK5,SATB1,PPP2R3A,OTUD1,SLC30A4,FUT9,PIK3AP1,MYC,LRP6,AFAP1L2,SH3PXD2B,IQGAP3,SMAD6,CHRM3,TBC1D8B,PTPN13,OGDHL,SNAP25,B4GALNT3,GPR137C,KHDRBS2,TMEM74,CTIF,EBF1,PTPRC,NAP1L5,TMCO3,SH3GL2,FAT4,TERT,PELI2,PTPRN2,GRIN2D,PLD1 |
| 1.473e-03 | -6.52 | GO_KINASE_ACTIVITY | MSigDB lists | GO_KINASE_ACTIVITY | 805 | 105 | 17377 | 1707 |
EPHA3,BTC,NEK10,MVK,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,FER,TNK2,MYLK3,MARK1,PDK1,PFKFB2,ACVR1C,KCNH5,PANK1,LRRK2,PRKCQ,ROR1,ACVR2B,FGF17,SGK2,FRK,FGFR1,MAGI3,TPK1,IRS2,DYRK1B,AK1,PRKCB,PLK2,PTK7,ERN1,PIK3C2B,MAPK13,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,SLK,EPHB1,PKN1,EFEMP1,IGF1R,ADCK1,PRKCD,SGK3,PRKG1,PRKG2,SGK1,ALPK1,MAST4,SYK,FES,PFKFB4,PAK1,FGFR4,CRIM1,MPP1,NUAK2,EFNA3,STRADB,OBSCN,AK4,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,MAP2K6,AKT3,HK2,MPP2,PGM2L1,NEK11,DLG2,PIP5KL1,LRRK1,HK1,CMPK2,PANK3 |
| 1.476e-03 | -6.52 | V$RSRFC4_Q2 | MSigDB lists | V$RSRFC4_Q2 | 196 | 33 | 17377 | 1707 |
TYRO3,ARHGAP26,GABRB2,SLCO3A1,NEDD4,TRPS1,HS3ST5,TSC22D1,BNIP3,TSPAN13,SSH3,USP2,RNF145,MGST3,NR4A1,TCEA3,FGF12,STRADB,TTYH2,ATF3,PRDM1,ZFPM2,ASPH,MBNL2,KPNA3,PMEPA1,DIRAS1,DLG2,TNFRSF17,CTNND2,FILIP1,AMPD1,CNTN1 |
| 1.476e-03 | -6.52 | LEE_LIVER_CANCER_SURVIVAL_UP | MSigDB lists | LEE_LIVER_CANCER_SURVIVAL_UP | 173 | 30 | 17377 | 1707 |
MVK,ACSL1,NECAB2,EHHADH,CYP2J2,PARD3B,OGDHL,COBLL1,NDRG2,ABCC2,WNT11,ITPR2,F12,ABHD6,AMDHD1,C4BPB,TSKU,INSIG1,SLC22A18,ALDH1L1,RUNDC3B,ZBTB20,MPDZ,MYRIP,AGL,CAND2,CRYL1,PCSK6,CES3,DENND5B |
| 1.476e-03 | -6.52 | GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN | MSigDB lists | GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN | 173 | 30 | 17377 | 1707 |
CARS,GDAP1,ANTXR2,GAPDH,BTNL9,PLAG1,ELMOD1,ADAMTS6,SNAP25,ZDHHC14,JAM3,BEX2,PLEKHB1,FKBP11,TMEM132B,MCOLN2,ID3,PIK3AP1,MSMO1,BACE2,ZDHHC6,ZBTB20,INPP5F,BMPR1A,TLR4,FKBP14,TC2N,CKAP4,ATP2B1,MEF2C |
| 1.476e-03 | -6.52 | V$EVI1_02 | MSigDB lists | V$EVI1_02 | 121 | 23 | 17377 | 1707 |
BCL11B,CHCHD7,ESRRG,PLAG1,RASD1,CREB5,TMEM47,ZFPM2,IKZF2,MBNL2,HOXA1,ADPRHL1,PTPRC,LRRN1,NCAM2,ADAMTS3,RASGRF2,HS3ST5,BCL6,NRP1,PPARGC1A,STON2,NKX2-1 |
| 1.479e-03 | -6.52 | MODULE_205 | MSigDB lists | MODULE_205 | 275 | 43 | 17377 | 1707 |
PRSS16,ZNF395,ST14,STXBP6,ITGA6,LRRC49,GPSM2,DNER,TIAM2,TBC1D19,TUBB4A,PPM1E,FBXO32,DNAH6,FBXL2,TSHR,MYRIP,FKBP14,SEMA6C,BOD1,DPYSL5,B9D1,VAV3,MSX1,TMEM65,EXOC6B,DNAJC6,DKK1,ZNF93,IFT81,CACHD1,KCNK15,ICA1,ZNF266,EIF4EBP1,SERPINI1,INPP5F,BMP4,SEPT5,TANC2,KIF1B,HEY1,RRAGD |
| 1.481e-03 | -6.52 | FRASOR_RESPONSE_TO_ESTRADIOL_DN | MSigDB lists | FRASOR_RESPONSE_TO_ESTRADIOL_DN | 79 | 17 | 17377 | 1707 |
DBN1,MYO1B,BIK,LITAF,COL4A5,DDIT4,SMAD3,NELL2,RND3,PLK2,LAMB1,MATN2,BMP4,STXBP1,SLIT2,DUSP1,ABCG1 |
| 1.481e-03 | -6.52 | GO_DENDRITE_DEVELOPMENT | MSigDB lists | GO_DENDRITE_DEVELOPMENT | 79 | 17 | 17377 | 1707 |
FARP1,RBFOX2,LRP4,VLDLR,SLITRK5,EPHB1,CTNNA2,BAIAP2,RERE,MAP1B,MAP2,MATN2,PRKG1,GRIP1,NRP1,SEMA3A,CTNND2 |
| 1.482e-03 | -6.51 | ConA-like_dom_sf | interpro domains | IPR013320 | 220 | 36 | 18492 | 1811 |
TRIM16L,CELSR1,LGALS3,TRIM16,CLGN,CELSR3,CNTNAP3,CLSTN2,COL18A1,GAS6,CANX,NRXN1,SEL1L3,COL14A1,ADGRG6,COL27A1,FSD1,COL22A1,NELL2,NBEA,COL19A1,LMAN2,PROS1,NPTXR,SLIT2,MID2,BTNL9,PTPRU,RYR2,TRIM9,FAT4,TRIM34,THBS4,FAT1,NRP1,MID1 |
| 1.486e-03 | -6.51 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | 708 | 94 | 17377 | 1707 |
GXYLT2,RECK,HEBP1,ATP8A1,FHDC1,KCTD12,ABAT,KIAA1217,FAM13A,DDR1,IKZF2,SLCO3A1,CDS1,EPCAM,ZNF362,TGFBR3,MARVELD2,ARL4D,VWA5A,RCAN3,CPE,GATM,RAPGEF5,SLIT2,EIF4E3,PNRC1,COL4A3,SMAD9,TMEM43,PFKFB2,C3orf52,SHANK2,NFIA,VIM,TNS1,DOCK5,SESN1,GSN,IGIP,SH3RF1,GPR160,ZBTB20,MAPK13,MAGI2,LIFR,CRYL1,UST,MAN2B2,ANO10,WASF3,MXI1,TBC1D1,NEO1,RNF141,ABLIM1,KIAA1671,TSC22D1,OPN3,RALGAPA2,ACTA2,PRICKLE2,SGK1,TSPAN12,LIMCH1,SAMD13,VGLL4,TNFRSF11A,ZFP36L2,SMPDL3A,PAK1,EPB41L5,SLC40A1,ARAP2,ALDH2,RNF170,PTPN13,ASAP3,SPATA13,WWC1,PHACTR2,SNTB1,CLN5,LEPR,RERE,BEX4,DEXI,CACHD1,NSD1,FBN1,MATN2,CLMN,TBC1D4,CACNA2D1,ABCG1 |
| 1.487e-03 | -6.51 | ZHENG_FOXP3_TARGETS_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_UP | 24 | 8 | 17377 | 1707 |
P4HA1,COBLL1,PRDM1,NRP1,IKZF2,SNX9,UBASH3B,FAM107B |
| 1.487e-03 | -6.51 | SHI_SPARC_TARGETS_UP | MSigDB lists | SHI_SPARC_TARGETS_UP | 24 | 8 | 17377 | 1707 |
AHRR,SEMA3C,SEMA4F,RAB27B,PRKCB,SEMA6A,DDIT3,MME |
| 1.493e-03 | -6.51 | lyase activity | molecular function | GO:0016829 | 182 | 31 | 17224 | 1680 |
EHHADH,ALOX5AP,ENO2,UROS,CLYBL,MGST3,MVD,ADCY1,HACD1,ACO1,FASN,CBS,CHAC1,GUCY1A2,TGDS,CA8,ETNPPL,CA13,CENPV,CA2,APLF,ALDOC,ALDOA,PAM,ADCY6,PHYKPL,PCK2,GGACT,ENO1,CTH,GLDC |
| 1.493e-03 | -6.51 | GSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_UP | MSigDB lists | GSE6566_STRONG_VS_WEAK_DC_STIMULATED_CD4_TCELL_UP | 158 | 28 | 17377 | 1707 |
ATL1,PCDH18,SSH3,MYO1D,NR4A1,NPM3,MVD,CD276,LDLR,DHCR24,SLITRK5,FAM102B,FEZ1,HERC5,BATF,ARRDC4,SPINK5,CBLN1,ISG20,DDAH1,CNTN4,GAS2L3,HK2,KLF5,DHCR7,TESC,SPOCK3,LAMP3 |
| 1.497e-03 | -6.50 | BOYLAN_MULTIPLE_MYELOMA_C_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_DN | 53 | 13 | 17377 | 1707 |
IRS2,BCL11B,PLOD2,MAP9,TSC22D1,LAPTM4B,RNF125,ENAH,AIG1,PDE4D,DOCK5,RAB30,B4GALT6 |
| 1.498e-03 | -6.50 | small GTPase binding | molecular function | GO:0031267 | 564 | 77 | 17224 | 1680 |
EXPH5,DMXL2,BTC,DOCK1,DENND3,DOCK2,TBC1D30,TIAM2,ARHGEF10L,ADPRHL1,UNC13B,RTKN2,MET,MYRIP,RAPGEF5,RASGRP1,PDGFRB,TBC1D8,LRRK2,PREX1,FGF17,TBC1D16,SERGEF,FGFR1,ARHGEF26,IRS2,RANBP2,RASGRF2,PLEKHG1,ADRB1,HGF,HACE1,DENND5B,FARP1,STXBP5L,ARHGEF11,PAK5,TBC1D1,STXBP6,RUSC2,IPO5,EPS8,PKN1,ARHGAP44,RAB11FIP5,MCF2L,SRGAP1,IQGAP3,TBC1D9,NCAM1,YBX3,DENND1C,FMNL2,GFRA1,RIMS2,RNF152,FGFR4,PAK1,VAV3,RIN2,ARHGEF28,ARAP2,TBC1D8B,RAPGEF2,MCF2L2,RAPGEF4,ASAP3,SPATA13,OBSCN,AGAP2,PEX5L,TBC1D2,DOCK7,PKN3,SH3BP4,GRIN2D,TBC1D4 |
| 1.501e-03 | -6.50 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_27 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_27 | 10 | 5 | 17377 | 1707 |
NPM1,ARHGAP26,NSD1,LIFR,PDGFRB |
| 1.503e-03 | -6.50 | GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | MSigDB lists | GO_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 35 | 10 | 17377 | 1707 |
SCN5A,SCN1B,CACNB2,ANK2,FGF12,RYR2,PKP2,ATP1B1,CACNA2D1,GJC1 |
| 1.503e-03 | -6.50 | GO_CALCIUM_CHANNEL_REGULATOR_ACTIVITY | MSigDB lists | GO_CALCIUM_CHANNEL_REGULATOR_ACTIVITY | 35 | 10 | 17377 | 1707 |
PRKCB,CACNB2,SGK3,PACSIN3,PRKG1,SGK1,TSPAN13,SGK2,NRXN1,HPCAL4 |
| 1.516e-03 | -6.49 | GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | MSigDB lists | GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 19 | 7 | 17377 | 1707 |
PKP2,RYR2,TRPM4,DSP,ANK2,DSG2,NOS1AP |
| 1.516e-03 | -6.49 | TERAMOTO_OPN_TARGETS_CLUSTER_7 | MSigDB lists | TERAMOTO_OPN_TARGETS_CLUSTER_7 | 19 | 7 | 17377 | 1707 |
GPT2,PHGDH,UGDH,PSPH,CTH,TFAP2A,WARS |
| 1.519e-03 | -6.49 | cardiac ventricle morphogenesis | biological process | GO:0003208 | 74 | 16 | 17256 | 1658 |
GATA3,PKP2,SMARCD3,RYR2,ZFPM2,DSP,HEG1,TGFBR3,HEYL,SEMA3C,BMP4,BMPR1A,TPM1,CPE,MEF2C,HEY1 |
| 1.524e-03 | -6.49 | action potential | biological process | GO:0001508 | 102 | 20 | 17256 | 1658 |
TRPM4,SCN5A,GRIK2,CACNA1E,SCN8A,ANK2,FGF12,RYR2,PKP2,KCND3,ATP1B1,GJC1,KCNMB4,KCNN2,SCN1B,CACNB2,KCNMB3,SCN2A,SCN3A,CACNA2D1 |
| 1.524e-03 | -6.49 | GO_COLLAGEN_TRIMER | MSigDB lists | GO_COLLAGEN_TRIMER | 86 | 18 | 17377 | 1707 |
COL9A3,COL6A2,C1QTNF3,COL4A3,COL4A4,MSR1,COL18A1,COL4A5,COLEC10,COL14A1,COL27A1,COL22A1,CCBE1,COL25A1,C1QL4,EMILIN2,COL19A1,COL9A2 |
| 1.524e-03 | -6.49 | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | 86 | 18 | 17377 | 1707 |
TYRO3,DYRK3,TUBA1A,RASAL2,ATP9A,CAP2,CHUK,NPC2,STK24,ABLIM1,PDLIM3,PMAIP1,GBP1,SH3BP4,ACTA2,GEM,TPM1,PTPRE |
| 1.524e-03 | -6.49 | GO_POST_EMBRYONIC_DEVELOPMENT | MSigDB lists | GO_POST_EMBRYONIC_DEVELOPMENT | 86 | 18 | 17377 | 1707 |
BCL11B,INPPL1,KDM5B,ARID5B,ACO1,GATA3,GABRG2,PRDM1,ACVR2B,PYGO1,PLEKHA1,HEG1,FOXP2,EFEMP1,FBN1,SEMA3C,BMP4,DHCR7 |
| 1.524e-03 | -6.49 | GO_REGULATION_OF_STEM_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_STEM_CELL_PROLIFERATION | 86 | 18 | 17377 | 1707 |
VEGFC,DISC1,LRRK2,SMARCD3,YAP1,WNT11,OVOL2,FGFR1,PTPRC,FOXP2,EPCAM,IRS2,TERT,MYC,BMP4,BMPR1A,SHOX2,SNAI2 |
| 1.524e-03 | -6.49 | NGUYEN_NOTCH1_TARGETS_DN | MSigDB lists | NGUYEN_NOTCH1_TARGETS_DN | 86 | 18 | 17377 | 1707 |
GARS,PTPN13,ASS1,FNDC3A,HERPUD1,PCDH7,F3,IGF1R,MYC,STC2,XBP1,ITGA2,TFAP2A,KLF5,ERCC5,MARCKS,TNFSF4,SERPINH1 |
| 1.527e-03 | -6.48 | GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP | MSigDB lists | GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP | 181 | 31 | 17377 | 1707 |
PLA2G4A,WASF3,RGS16,USP2,RHOQ,RASAL2,RNF144A,SLC39A8,ST6GAL1,SELL,GSTO1,ABAT,GUCY1A2,PALLD,LCP2,TPD52L1,CTNNA2,PPP2R3A,CHST10,F3,RANBP2,MAGEA12,MYC,ATRNL1,PTPRN2,RPS12,GFI1,ZNF460,PTPRE,SMPDL3A,IGSF3 |
| 1.527e-03 | -6.48 | GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_UP | MSigDB lists | GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_UP | 181 | 31 | 17377 | 1707 |
RIN2,BMPR2,IL15,APBB1,CYP4V2,NDRG2,GSTO1,CTBP2,PEX5L,P2RY1,TCERG1L,RNF44,LDHD,MECOM,BEX4,PKN3,ALDOC,ALDH1L1,WDR19,BDH2,MPPED2,GSTM3,SQLE,NAP1L3,PROS1,RNF130,MORN4,SNX10,FKBP14,DIRC2,CYP1B1 |
| 1.527e-03 | -6.48 | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | MSigDB lists | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | 181 | 31 | 17377 | 1707 |
DZANK1,DMXL2,FARP1,ENO2,SKAP2,PLEKHA8,AGPAT4,KIF5C,HIP1,CHSY1,CCNG1,SNX9,CRYBG3,EPCAM,ARHGAP21,IKZF3,PTPRJ,HLF,FUT9,CDC14B,GPR155,CLDN12,RAB31,NBEA,STXBP1,RNF157,FMNL2,TC2N,CSRP2,CHMP4C,DUSP1 |
| 1.527e-03 | -6.48 | GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | MSigDB lists | GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | 181 | 31 | 17377 | 1707 |
B9D1,VEGFC,LONRF1,ATL1,VNN2,STXBP5L,DOCK1,NR4A1,REL,LPCAT2,ADAMTS6,ABCC2,ISYNA1,NIPSNAP3B,SPIRE1,BAIAP2,TRIM9,GPR15,ATPAF2,CXCL10,KIAA0895,BACE2,MCF2L,RASGRF2,JAKMIP2,MYOM2,CADPS2,AMPD1,CHMP4C,HACE1,DUSP1 |
| 1.535e-03 | -6.48 | regulation of anatomical structure size | biological process | GO:0090066 | 494 | 68 | 17256 | 1658 |
FGF13,TMSB15A,PLXNA2,ADD2,NTRK3,RAC3,PPP1R9A,SCIN,RND2,CTTN,SLIT2,NEB,FER,SSH3,EVL,DCC,DSTN,LRRK2,DEPTOR,PREX1,DOCK5,HTR7,GSN,KCNMB4,WIPF3,NCKAP1L,ADRB1,ARHGAP28,PTPRS,TMOD2,SEMA3C,OXTR,ATG5,SPART,NRP1,TENM1,BMPR2,FN1,EPS8,SLC12A6,P2RY1,PFN2,SPIRE1,FHOD3,NKX6-1,SEMA4F,PRKCD,PRKG1,ADCY6,ACTA2,IQGAP3,PRR16,CHRM3,HMGCR,NOS3,TRPM4,PAK1,BDNF,VAV3,RAB3B,PLS1,BAIAP2,MAP1B,PLEKHH2,MYADM,AKT3,SEMA3A,SHTN1 |
| 1.535e-03 | -6.48 | RHEX (regulator of hemoglobinization and erythroid cell expansion) | protein interactions | 440712 | 14 | 6 | 17029 | 1718 |
PLD1,PKN1,PLXDC2,NOS1AP,JPH1,TMTC4 |
| 1.536e-03 | -6.48 | ZHANG_TLX_TARGETS_UP | MSigDB lists | ZHANG_TLX_TARGETS_UP | 107 | 21 | 17377 | 1707 |
SESN2,SORBS1,RNF145,NR4A1,CCNG1,ABHD4,SLCO3A1,SLC19A2,GABARAPL1,DDIT4,AK1,GSN,NACC2,CSF1,TSC22D1,OPN3,VWA5A,APBA2,PTPRE,DDIT3,STOM |
| 1.536e-03 | -6.48 | MODULE_456 | MSigDB lists | MODULE_456 | 107 | 21 | 17377 | 1707 |
MICAL2,BCL7A,MSX1,SIDT1,SH2D2A,GPR65,STAT4,GJB2,CR2,PRKAR2B,CTTNBP2NL,SATB1,DENND3,CBLN1,TRIB3,PTK7,STARD4,BCL6,TOX,MAPK10,MME |
| 1.548e-03 | -6.47 | GO_FOREBRAIN_GENERATION_OF_NEURONS | MSigDB lists | GO_FOREBRAIN_GENERATION_OF_NEURONS | 66 | 15 | 17377 | 1707 |
BCL11B,DISC1,NUMBL,ROBO2,GATA2,RAPGEF2,LHX6,SATB2,DLX2,NRP1,SEMA3A,SLIT2,RAC3,FGFR1,NKX2-1 |
| 1.548e-03 | -6.47 | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | MSigDB lists | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 66 | 15 | 17377 | 1707 |
EPCAM,ID1,CA2,NR4A1,PLK2,FZD8,VAMP8,TSC22D1,BCL6,SGK1,ATF3,BMP4,NRP1,F3,DUSP1 |
| 1.550e-03 | -6.47 | cell-cell junction assembly | biological process | GO:0007043 | 95 | 19 | 17256 | 1658 |
CDH26,UGT8,ANK2,GJB2,ARL2,PKP2,TJP1,WNT11,PRKCA,HEG1,PATJ,GJC1,EPB41L3,MPP7,MARVELD2,POF1B,TLN2,CDH2,OCLN |
| 1.553e-03 | -6.47 | nucleoside diphosphate metabolic process | biological process | GO:0009132 | 81 | 17 | 17256 | 1658 |
AK1,GAPDH,ENO2,PFKFB2,MPP1,ALDOC,ALDOA,MPP2,OGDHL,HK2,PGM2L1,AK4,DLG2,HK1,CMPK2,ENO1,MAGI3 |
| 1.553e-03 | -6.47 | EGF_CA | pfam domains | PF07645 | 73 | 16 | 17054 | 1666 |
EFEMP1,NELL2,FAT4,FBN1,THBS4,CCBE1,MATN2,VLDLR,LDLR,BMP1,EGFL7,PROS1,GAS6,HMCN1,TLL2,HEG1 |
| 1.554e-03 | -6.47 | positive regulation of intracellular signal transduction | biological process | GO:1902533 | 1035 | 128 | 17256 | 1658 |
LMCD1,GATA3,PRKCA,STK24,NOS1AP,F3,GSDME,PMAIP1,EPHB6,TLR4,RASGRP1,PDGFRB,CYP1B1,GCNT2,ATF4,WLS,TGFA,LRRK2,ROR1,FGF17,GPRC5B,HPSE,PLK2,ERN1,ADRB1,TNFRSF1A,DIRAS1,NRP1,UNC5B,RRAGD,TYRO3,SORBS3,TNFRSF10C,TNFRSF19,CHD5,IL18R1,MYORG,IGF1R,PIK3AP1,INAVA,ZNF385A,HMGCR,PAK1,FGFR4,RPL26,MID2,DUSP9,HIP1,WWC1,PDE8A,PLCB1,MAPKAPK2,PELI2,CSF1,CDH2,SEMA3A,EPHA3,BTC,PRKN,AVPI1,NEK10,IL15,GPR65,NTRK3,CHUK,DDR1,PIBF1,TLR3,DAB2IP,MET,CTH,IGFBP3,FZD4,PTPN6,WNT11,GSTO1,ATF3,CD40,FGFR1,IRS2,CXCL10,PTPRJ,PRKCB,APELA,DUSP19,MAP3K21,HGF,TNFSF15,MAPK10,MID1,TENM1,TNIK,NECAB2,EDA2R,FZD8,REL,P2RY1,GAS6,NDFIP2,EPHB1,PKN1,TPD52L1,NEDD4,RASD2,GHR,IQGAP3,SPRY2,SYK,TNFRSF11A,PARP9,GSTM2,MSX1,RAPGEF2,LITAF,GAREM1,RACK1,TLR6,DKK1,GPR37,FGR,EDA,NACC2,AKT3,MAP2K6,LRRK1,BMP4,MAP3K20,DDIT3 |
| 1.560e-03 | -6.46 | digestive tract morphogenesis | biological process | GO:0048546 | 48 | 12 | 17256 | 1658 |
SMAD3,EPB41L5,DACT1,RBPMS2,HOXD13,WNT11,ACVR2B,BMP4,OVOL2,SHOX2,SIX2,GLI1 |
| 1.561e-03 | -6.46 | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP | 166 | 29 | 17377 | 1707 |
MICAL2,RGS16,EIF4E3,CLGN,WLS,PTPN13,FAM84A,SETBP1,HERC5,PHACTR2,GPSM2,NDFIP2,IKZF2,TRPS1,ISG20,EPCAM,DOCK7,EOMES,GRHL1,PLOD2,TACC2,PLK2,PRELID2,CCDC146,BDH2,SERPINI1,TOX,TNFSF4,NEB |
| 1.561e-03 | -6.46 | JIANG_TIP30_TARGETS_UP | MSigDB lists | JIANG_TIP30_TARGETS_UP | 41 | 11 | 17377 | 1707 |
ENPP1,EEF2,ITGA6,LAMB1,BCL6,P4HA1,CALCRL,CDH2,RAPGEF5,DUSP1,IGFBP3 |
| 1.562e-03 | -6.46 | dorsal/ventral pattern formation | biological process | GO:0009953 | 88 | 18 | 17256 | 1658 |
INTU,NBL1,LRP4,OVOL2,FOXG1,SP8,NKX6-1,WDR19,TBC1D32,LRP6,BMP4,DISP1,BMPR1A,DYNC2H1,SMAD6,FOXA1,NKX2-1,GLI1 |
| 1.568e-03 | -6.46 | positive regulation of ion transport | biological process | GO:0043270 | 241 | 38 | 17256 | 1658 |
SCN5A,LGALS3,ATP8A1,VAMP8,PKP2,P2RY1,ABAT,NOS1AP,LRRC55,SCN1B,KMO,CNKSR3,CACNB2,PRKCD,EHD3,PRELID1,TRPC1,STXBP1,TNFRSF11A,HSPA2,PDGFRB,ALG10B,RAB3B,GSTM2,ANK2,FGF12,RYR2,GSTO1,AMIGO1,ATP1B1,SNCA,CXCL10,MAP2K6,WFS1,TRPC3,TESC,CACNA2D1,CNTN1 |
| 1.569e-03 | -6.46 | amyloid-beta binding | molecular function | GO:0001540 | 60 | 14 | 17224 | 1680 |
BCHE,BACE2,FZD4,COL25A1,BACE1,LDLR,APBB1,ITGA2,MSR1,LILRB1,APBA1,APBA2,ATP1A3,GSAP |
| 1.571e-03 | -6.46 | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | MSigDB lists | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | 561 | 77 | 17377 | 1707 |
TRIM2,ACSL1,SIDT1,RECK,KIF5A,VAMP8,OTX1,PLXNA2,ABHD13,COBLL1,ENAH,SLC7A2,CHAC1,NCS1,SIPA1L2,PPM1E,ZNF362,TGFBR3,KCNAB1,MAP7,ACVR2A,TUBA1A,ANK2,ATF7IP2,RNF125,SATB2,PLEKHA1,SESN1,ASPH,DCBLD2,SMAD3,BACH2,RNF217,ITGA2,DSEL,SPRY4,KCTD1,GPR63,LATS2,ANKRD13B,STOX2,ZHX3,OTOGL,PLAG1,BACE1,PSD3,ARL2,FAM81A,DYNC1I1,CHD5,FSD1,LRRC55,NAV1,BACE2,PCBP4,GHR,TFAP2A,LRP6,SGK1,STXBP1,BDNF,CRIM1,SLC36A1,ESRRG,LITAF,STRADB,AK4,FERMT2,ZIC1,SH3GL2,AKT3,C1orf21,SH3BGRL2,KIF21A,CERS1,KIF1B,BTRC |
| 1.572e-03 | -6.46 | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_DN | 189 | 32 | 17377 | 1707 |
MYCBP2,RASAL2,LCP2,ABHD4,DDR1,CHST10,SPIRE1,DDIT4,RTN1,EPB41L3,GALNT1,GPR155,ITGB3,DAB2IP,POU2F2,TSPAN9,CEBPD,B4GALT6,PTPN6,SESN1,TEX9,TMEM74,BCL11A,GSN,PRKCB,PRCP,CDH17,INPP5F,SERPINI1,DBP,FRMD5,CTNND2 |
| 1.572e-03 | -6.46 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP | 189 | 32 | 17377 | 1707 |
GNG12,SLC6A9,TUBA1A,DHCR24,MCTP2,MCOLN3,KCTD12,OR51B4,PRDM1,MFSD6,SLC46A3,SNX9,CD53,MCOLN2,SMAD3,ENPP1,RALGPS2,SLC30A4,TECPR2,ITGB3,RUNDC3B,RAB31,ADRB1,DYNC2LI1,ARHGAP28,EPHB6,MYO6,MORN4,ZNF365,PRR16,DHCR7,RAPGEF5 |
| 1.579e-03 | -6.45 | PET | prosite domains | PS51303 | 6 | 4 | 12060 | 1278 |
PRICKLE1,PRICKLE2,TES,LMCD1 |
| 1.581e-03 | -6.45 | GO_CATION_CHANNEL_ACTIVITY | MSigDB lists | GO_CATION_CHANNEL_ACTIVITY | 284 | 44 | 17377 | 1707 |
KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,SCN8A,MCOLN3,ITPR2,GAS6,KCNC4,CACNB4,NCS1,MCU,MCOLN2,KCNJ4,KCNN2,CHRNA5,KCNAB1,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,KCNH5,CACNA1E,RYR2,CHRNA6,RASA3,KCND3,KCNK15,KCNMB4,KCNG1,TRPC3,CACNA2D1,DENND5B |
| 1.582e-03 | -6.45 | GRPR (gastrin releasing peptide receptor) | protein interactions | 2925 | 52 | 13 | 17029 | 1718 |
MTG1,FADS1,RAB3B,ADCK1,ATP7B,ACVR2B,FAR2,USP30,FNDC3A,SLC35G2,SLC19A2,GJC1,CDS1 |
| 1.589e-03 | -6.44 | GO_MUSCLE_SYSTEM_PROCESS | MSigDB lists | GO_MUSCLE_SYSTEM_PROCESS | 276 | 43 | 17377 | 1707 |
SCN5A,SORBS1,IL15,ARHGEF11,PKP2,CHUK,SORBS3,P2RY1,EEF2,SCN1B,CACNB2,SMTN,PRKG1,ACTA2,PDE4D,NEB,CHRM3,NOS3,PXN,GSTM2,MSTN,ANK2,FGF12,RYR2,VIM,ATP1B1,SNTB1,ASPH,GJC1,HTR7,GSN,MAP2K6,GNAO1,ALDOA,MYOM2,INPP5F,TMOD2,OXTR,TPM1,PPARGC1A,CACNA2D1,ATP1A3,MEF2C |
| 1.590e-03 | -6.44 | GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | MSigDB lists | GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE | 450 | 64 | 17377 | 1707 |
SEMA6B,FN1,BMPR2,FGF13,EPS8,PLXNA2,ADD2,NTRK3,P2RY1,PFN2,SEMA6A,PPP1R9A,SPIRE1,FHOD3,SCIN,NKX6-1,RND2,SEMA4F,PRKCD,PRKG1,ACTA2,ADCY6,CTTN,IQGAP3,PRR16,SLIT2,NEB,SEMA6C,CHRM3,NOS3,HMGCR,TRPM4,SSH3,BDNF,DISC1,VAV3,FER,RAB3B,EVL,DCC,DSTN,LRRK2,DEPTOR,PREX1,PLS1,PRKCQ,DOCK5,BAIAP2,MAP1B,BCL11A,HTR7,GSN,KCNMB4,PLEKHH2,MYADM,NCKAP1L,WIPF3,ADRB1,SEMA3C,TMOD2,OXTR,ATG5,NRP1,SEMA3A |
| 1.591e-03 | -6.44 | PLCG1 (phospholipase C gamma 1) | protein interactions | 5335 | 162 | 29 | 17029 | 1718 |
FGFR4,PAK1,PRKN,VAV3,SH3BP2,SH2D2A,PTPN6,NPM1,AGAP2,NTRK3,RACK1,ARHGAP32,LCP2,DDR1,KHDRBS2,FGFR1,IRS2,CCDC120,BAG3,GSN,PTPRJ,GHR,NCAM1,MET,TRPC3,LIFR,SYK,PDGFRB,GAB2 |
| 1.593e-03 | -6.44 | V$NFKB_Q6 | MSigDB lists | V$NFKB_Q6 | 244 | 39 | 17377 | 1707 |
CXCR5,CGN,AMOTL1,SCAMP1,GRIK2,REL,NDRG2,DDR1,SATB1,PRRG4,ARHGAP44,CYP26A1,PCBP4,PRKCD,STC2,ST8SIA1,BDNF,RIN2,PCDH10,CACNA1E,ATP1B1,FGF17,CD40,GPR150,EBF1,NSD1,CXCL10,MSC,PTPRJ,GNAO1,PLXDC2,ERN1,UACA,TNFSF15,TNFSF4,HOXB9,PTGES,PURG,STON2 |
| 1.593e-03 | -6.44 | V$GR_Q6 | MSigDB lists | V$GR_Q6 | 244 | 39 | 17377 | 1707 |
TYRO3,KCNV1,CCDC126,PCDH18,KLF8,FGF13,PLAG1,SETBP1,IKZF2,CNTN4,FLRT3,LHX6,ACVR2A,ADCY6,PPP2R2B,NCAM1,RIMS2,FES,USP2,MEIS2,JPH1,FGF12,FGF17,SGK2,RERE,NEGR1,PLAGL1,LAMB1,B3GALT2,KLF5,DLG2,MBOAT2,NKX2-8,SHOX2,LIFR,MID1,CTNND2,RAB30,RRAGD |
| 1.597e-03 | -6.44 | V$CEBP_01 | MSigDB lists | V$CEBP_01 | 252 | 40 | 17377 | 1707 |
BCL11B,LRFN5,NUDT10,SV2B,NEK10,DNM3,FGF13,CHCHD7,OTX1,OVOL2,SPINK5,NEO1,MECOM,ANKRD42,PPM1E,ACVR2A,FIGN,POU3F3,NKX2-1,DZANK1,ENAM,ARAP2,GCNT2,TBC1D8B,PRDM1,ATOH1,PALLD,ARRDC4,SKAP1,KPNA3,KIAA0355,ABI3,DLG2,HS3ST3B1,TPM1,SHOX2,SEMA3A,PURG,HEY1,DOCK9 |
| 1.597e-03 | -6.44 | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | 252 | 40 | 17377 | 1707 |
TRIM2,TBC1D1,GATA3,PSD3,ADAMTS6,GABRR2,PRKCA,FAM174B,NEDD4,ARHGAP44,KIAA0895,TGFBR3,IGF1R,ACVR2A,PPP2R2B,ARL4D,RCAN3,PTPRCAP,MAST4,GATM,CEBPD,IGSF3,FZD1,PNMA2,FADS1,PAK1,PXN,PNP,HOMER2,EFHC2,MGAT4B,CR2,ATP11A,FGFR1,MAPKAPK2,GYPC,ADAMTS3,EIF4EBP1,XBP1,PLD1 |
| 1.598e-03 | -6.44 | SRC (SRC proto-oncogene, non-receptor tyrosine kinase) | protein interactions | 6714 | 373 | 56 | 17029 | 1718 |
EPHA3,TYRO3,EFNB2,RGS16,INPPL1,SORBS1,DOCK1,PTPN21,EPS8,CHUK,STAT5B,PRKCA,NDFIP2,NEDD4,FSD1,IGF1R,PRKCD,ITGB3,C1QL4,AFAP1L2,FHIT,CTTN,PDE4D,ERRFI1,MET,TLR4,ENO1,PTPRE,TNFRSF11A,SYK,PDGFRB,GAB2,TNK2,SH3BP2,PXN,EVL,SKAP2,SH2D2A,PTPN6,PRDM1,RACK1,ARHGAP32,KCND3,SKAP1,FGFR1,ISG20,SNCA,GSN,FGR,TERT,MAP2,CCNA1,TNFRSF1A,GRB10,PLD1,ATP2B4 |
| 1.607e-03 | -6.43 | regulation of heart rate by cardiac conduction | biological process | GO:0086091 | 36 | 10 | 17256 | 1658 |
TRPM4,SCN5A,SCN1B,CACNB2,ANK2,DSG2,PKP2,KCND3,DSP,CACNA2D1 |
| 1.607e-03 | -6.43 | heart valve morphogenesis | biological process | GO:0003179 | 36 | 10 | 17256 | 1658 |
ACVR1,BMPR2,HEYL,DCHS1,GATA3,BMP4,BMPR1A,SMAD6,HEY1,MEF2C |
| 1.607e-03 | -6.43 | GO_EMBRYONIC_MORPHOGENESIS | MSigDB lists | GO_EMBRYONIC_MORPHOGENESIS | 527 | 73 | 17377 | 1707 |
ACVR1,ST14,RECK,UGDH,OTX1,GATA3,SP8,SKI,SETDB2,EOMES,DLX6,DACT1,ITGB3,ACVR2A,PRKACB,GLI1,FZD1,INTU,NKX3-2,WLS,YAP1,SATB2,WNT11,ACVR2B,ATOH1,FGFR1,SMAD3,INSIG1,PTK7,LAMB1,ITGA2,DLX2,BMPR1A,NRP1,COBL,MEF2C,LATS2,RUNX2,BMPR2,FN1,CELSR1,LRP4,OVOL2,EFEMP1,GATA2,PDZD7,FRAS1,FLRT3,TFAP2A,LRP6,DYNC2H1,SPRY2,DUSP1,EPB41L5,VEGFC,B9D1,MICAL2,MSX1,MAFB,PRICKLE1,RYR2,HOXA1,ZIC1,DKK1,MMP15,FBN1,WDR19,PCGF2,HOXD13,BMP4,SHOX2,MMP16,SIX2 |
| 1.610e-03 | -6.43 | HALLMARK_GLYCOLYSIS | MSigDB lists | HALLMARK_GLYCOLYSIS | 197 | 33 | 17377 | 1707 |
QSOX1,MXI1,ENO2,TGFA,VLDLR,CAPN5,BIK,EFNA3,PKP2,SDC3,AK4,IL13RA1,LHPP,FAM162A,GLCE,DDIT4,ISG20,IRS2,PLOD2,P4HA2,ALDOA,STC2,SRD5A3,PAM,HK2,P4HA1,MET,ENO1,AGL,B4GALT7,CTH,IGFBP3,RRAGD |
| 1.610e-03 | -6.43 | forebrain cell migration | biological process | GO:0021885 | 61 | 14 | 17256 | 1658 |
TYRO3,NRG3,FGF13,LHX6,LAMB1,LRRK2,EFHC1,DAB2IP,NRP1,FOXG1,SEMA3A,SLIT2,POU3F3,NKX2-1 |
| 1.620e-03 | -6.43 | BROWNE_HCMV_INFECTION_48HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_48HR_UP | 174 | 30 | 17377 | 1707 |
TYRO3,COL9A3,RGS16,CD55,LRP4,CALCRL,NTRK3,ATF3,ITPR2,ATP11A,FAM13A,PRKCA,RNF44,IL18R1,BMP6,CTNNA2,SNCA,SLC39A14,FUT9,RUNDC3B,GEM,ZNF365,CPE,FNBP1L,LIFR,HSPA2,PTGES,COBL,CTH,ABCG1 |
| 1.620e-03 | -6.43 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | 174 | 30 | 17377 | 1707 |
TRDMT1,ZCCHC24,ST6GAL1,RPL21,IPO5,TMEM126A,RNF125,TMEM170B,UCHL3,ARRDC4,ATP10D,LRAT,RPL13A,RPL34,RANBP2,TRIB3,EEF2,PMEPA1,IGIP,GPR155,PEMT,FAM168A,ALDOA,NDUFB8,ZNF704,P4HA1,LAPTM4B,PJA1,VGLL4,MID1 |
| 1.620e-03 | -6.43 | GO_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_TYROSINE_KINASE_ACTIVITY | 174 | 30 | 17377 | 1707 |
EPHA3,FGFR4,TYRO3,TNK2,FER,BTC,DYRK3,CRIM1,EFNA3,NTRK3,STAT5B,FGF17,ROR1,EPHB1,FRK,DDR1,PEAK1,FGFR1,DYRK1B,EFEMP1,FGR,IGF1R,MAP2K6,PRKCD,EPHB6,NRP1,MET,SYK,PDGFRB,FES |
| 1.620e-03 | -6.43 | GSE13411_NAIVE_VS_MEMORY_BCELL_UP | MSigDB lists | GSE13411_NAIVE_VS_MEMORY_BCELL_UP | 174 | 30 | 17377 | 1707 |
MOCOS,TNIK,MEIS2,RUNX2,ZNF395,GRB14,C3orf52,PTPN21,ADAMTS6,OVOL2,KCND3,ZFPM2,CD40,EPHB1,PALLD,BBS9,ARHGAP44,IQCH,PTPRJ,CHN2,ZNF440,RAI14,SVIL,NXPH4,FBXL2,KLHL29,LIFR,NEB,RBMS2,SNAI2 |
| 1.625e-03 | -6.42 | positive regulation of response to stimulus | biological process | GO:0048584 | 2194 | 250 | 17256 | 1658 |
ACVR1,LGR4,TRIM16,LDLR,VAMP8,LMCD1,LILRB1,GATA3,CTBP2,STAT5B,ABAT,PRKCA,EYA4,STK24,NOS1AP,SKI,F3,GSDME,TGFBR3,PMAIP1,CFHR1,FAM168A,ITGB3,HRK,EPHB6,TLR4,SLIT2,PRKACB,RASGRP1,PDGFRB,CYP1B1,CD55,GCNT2,ATF4,SKAP2,WLS,TGFA,LRRK2,YAP1,CR2,ACVR2B,ROR1,FGF17,F12,PLEKHA1,INHBC,GSN,GPRC5B,HPSE,WIPF3,NCKAP1L,CCBE1,PLK2,ERN1,ADRB1,TNFRSF1A,BBC3,MAPK13,TMOD2,DIRAS1,NRP1,TNFSF4,UNC5B,MLLT3,MEF2C,RRAGD,TYRO3,SORBS3,CHSY1,TNFRSF10C,TNFRSF19,CHD5,IL18R1,MYORG,IL17D,CHN1,IGF1R,PIK3AP1,GATA2,MYC,LRP6,INAVA,BNIP3,STXBP1,ZNF385A,RIMS2,HMGCR,PAK1,FGFR4,RPL26,MID2,BDNF,ATP5IF1,DISC1,MSTN,BTNL9,MYO10,SH2D2A,DUSP9,NSD2,HIP1,WWC1,PDE8A,C1R,PLCB1,FAM162A,HERPUD1,BAIAP2,MAPKAPK2,RIPOR2,ADAMTS3,PELI2,THBS4,CSF1,INHBE,SEMA3A,TRPC3,CDH2,SFN,EPHA3,PRKN,BTC,SORBS1,NEK10,AVPI1,CFH,IL15,DOCK1,C4A,GPR65,CHUK,NTRK3,LCP2,NRXN1,COLEC10,PIBF1,DDR1,TLR3,UNC13B,DACT1,SHF,ACVR2A,DAB2IP,PDE4D,MET,GLI1,CTH,IGFBP3,GAB2,INTU,FZD4,PTPN6,SHANK2,ATF3,PRKCQ,WNT11,GSTO1,RARRES2,CD40,FGFR1,C4BPB,SNCA,IRS2,SMAD3,CXCL10,PTPRJ,GYPC,PRKCB,APELA,ITGA2,MAP3K21,DUSP19,TNFSF15,HGF,GRB10,BMPR1A,DISP1,SUSD4,MAPK10,MID1,TENM1,TNIK,NECAB2,BMPR2,EDA2R,GRB14,REL,CD276,FZD8,APBB1,EPS8,BIK,TNFSF13B,GAS6,P2RY1,PKN1,EPHB1,NDFIP2,TPD52L1,TSPAN17,BMP6,NEDD4,NEO1,CHN2,PRKCD,GHR,RASD2,AFAP1L2,DYNC2H1,IQGAP3,GFI1,TNFRSF11A,TESPA1,SYK,SPRY2,PARP9,TRPM4,VEGFC,VAV3,SH3BP2,MSX1,GSTM2,RAB3B,RAPGEF2,SYBU,LITAF,GAREM1,RACK1,SKAP1,TLR6,MGMT,DKK1,GPLD1,GPR37,PTPRC,FGR,EDA,NACC2,TERT,MPP7,MAP2K6,AKT3,XBP1,BMP4,LRRK1,SHOX2,MAP3K20,DDIT3,BTRC,FOXA1 |
| 1.646e-03 | -6.41 | GO_SIGNALING_ADAPTOR_ACTIVITY | MSigDB lists | GO_SIGNALING_ADAPTOR_ACTIVITY | 73 | 16 | 17377 | 1707 |
CHN1,VAV3,SH3BP2,CHN2,SORBS1,SKAP2,MPP7,SH2D2A,GRB14,EPS8,DUSP19,AFAP1L2,DAB2IP,GRB10,SKAP1,GAB2 |
| 1.647e-03 | -6.41 | GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 159 | 28 | 17377 | 1707 |
PFKFB4,RWDD2A,RIN2,ANTXR2,MYO10,ST6GAL1,LRRK2,PREX1,CALCRL,KCTD12,CEBPA,CTBP2,KIF21B,BBS9,RAC3,ENPP1,TLR3,IKZF3,FBXO32,HPSE,GPR155,EHD3,RAB31,PIK3C2B,MET,MAST4,RASGRP1,FES |
| 1.650e-03 | -6.41 | GO_RESPONSE_TO_ACID_CHEMICAL | MSigDB lists | GO_RESPONSE_TO_ACID_CHEMICAL | 309 | 47 | 17377 | 1707 |
EPHA3,PRKAA2,ACSL1,FN1,TRIM16,IPO5,ASS1,COL18A1,CHUK,NTRK3,AARS,BMP6,ASNS,TGFBR3,ZNF354A,EEF2,BCHE,SREBF1,TFAP2A,ADCY6,PDGFRB,DUSP1,FGFR4,GDAP1,FZD4,YAP1,WNT11,ABCC2,CPEB1,MGMT,DKK1,CEBPB,ID3,GSN,PTK7,ACER2,PEMT,XBP1,ITGA2,SH3BP4,BMP4,TNFSF4,PPARGC1A,TESC,PTGES,ATP2B4,RRAGD |
| 1.650e-03 | -6.41 | GO_TRANSPORTER_COMPLEX | MSigDB lists | GO_TRANSPORTER_COMPLEX | 309 | 47 | 17377 | 1707 |
KCNV1,SCN5A,CACNG3,GRIK2,GABRB2,SCN8A,EPS8,GABRG2,GABRR2,CACNB4,KCNC4,ABHD6,NOS1AP,MCU,KCNJ4,KCNAB1,CHRNA5,SCN1B,CACNB2,KCNS3,KCNMB3,CTTN,PDE4D,SCN2A,HSPA2,SCN3A,KCNB2,KCNIP3,KCNQ3,CACNA1E,SHANK2,TTYH2,CHRNA6,RYR2,SNAP25,KCND3,ATP1B1,AMIGO1,ASPH,HERPUD1,GRIK4,KCNMB4,KCNG1,GRIN2D,DLG2,CACNA2D1,ATP1A3 |
| 1.668e-03 | -6.40 | TGCTGAY_UNKNOWN | MSigDB lists | TGCTGAY_UNKNOWN | 502 | 70 | 17377 | 1707 |
PLBD2,TRIM2,CACNG3,LGR4,FGF13,HEBP1,SLC7A2,PPM1E,SLC22A17,ABI3BP,PPFIA2,COL19A1,HRK,PPP2R2B,SNX10,ETV1,NKX2-1,MEIS2,MYLK3,PRKCQ,ROR1,KCND3,ALDOA,TIGD4,INPP4B,NRP1,HOXB9,NR3C2,PURG,STON2,RAB30,FRMD5,GPR63,PRKAA2,TYRO3,PCDH18,ANKRD13D,CCDC148,MXI1,FAM124A,IGFBP6,PLAG1,GALNT13,PKN1,FOXP2,NUMBL,LRRN1,PCBP4,VGLL4,FES,RNF152,NDUFA4L2,GPR176,PCDH10,RHOQ,USP2,NR4A1,CACNA1E,PRDM1,SNAP25,ZFPM2,SKAP1,NSD1,RPL28,C1orf21,SH3BGRL2,LRRK1,FILIP1,DDIT3,PHC1 |
| 1.672e-03 | -6.39 | - | gene3d domains | 3.90.190.10 | 87 | 19 | 8148 | 867 |
SSH3,DUSP8,PTPRU,PTPRD,PTPN6,PTPN13,PTPN21,DNAJC6,DUSP9,TNS1,PTPRC,PTPRJ,CDC14B,PALD1,DUSP19,PTPRS,PTPRN2,PTPRE,DUSP1 |
| 1.672e-03 | -6.39 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | 182 | 31 | 17377 | 1707 |
MPZL3,SERINC5,SH3BP2,ALDH2,LGALS3,SEC24D,MYO10,SLC36A1,NR4A1,GALNT6,RAPGEF2,ST6GAL1,FOXN3,EXOC6B,DNAJC6,YPEL2,PRDM1,MFSD6,ZNF362,TMEM154,GYPC,RALGPS2,TRIM34,AKT3,INPP4B,INPP5F,EPHB6,TESC,MLLT3,RASGRP1,DUSP1 |
| 1.672e-03 | -6.39 | GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_UP | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_UP | 182 | 31 | 17377 | 1707 |
MYO1D,ITGB7,GAPDH,PDE1B,COL4A3,AKAP5,JDP2,COL4A4,PPFIBP2,PREX1,RASA3,SATB2,VIM,COTL1,BATF,PHGDH,MAGI3,ARHGAP44,HOMER3,SFXN1,EHD3,PRKCD,SLC7A5,ATRNL1,ACTA2,MARCKS,HK1,TBC1D9,SLC1A5,MAST4,ATP2B4 |
| 1.678e-03 | -6.39 | MODULE_118 | MSigDB lists | MODULE_118 | 392 | 57 | 17377 | 1707 |
RGS16,GNG12,FN1,ALOX5AP,ENO2,ITGA6,UGDH,LDLR,BIK,ZIC2,KIF21B,MLC1,DOCK2,RAC3,PHLDA2,GAS1,DDIT4,CD53,EFEMP1,EPCAM,EPB41L3,SLC7A11,TACC2,MYC,SMTN,GULP1,IL1RAP,IGSF3,CYP1B1,FADS1,DBN1,PRAME,PNP,KCNQ3,MYO10,CRIM1,PFKFB2,NPM3,LRMP,KCND3,DSP,FGFR1,PTPRC,CD37,INSIG1,RND3,PLOD2,EIF4EBP1,LAMB1,SLC7A5,RAI14,RAB31,RGS10,DBP,TPM1,CDH2,CSRP2 |
| 1.679e-03 | -6.39 | human chr7p14.3 | chromosome location | human chr7p14.3 | 53 | 11 | 26185 | 1967 |
FKBP9,CHN2,GARS,CPVL,PLEKHA8,WIPF3,SCRN1,MTURN,BBS9,DPY19L1P1,FKBP14 |
| 1.679e-03 | -6.39 | back | COSMIC cancer mutations | back | 311 | 47 | 17385 | 1698 |
OR51B5,EXPH5,TNIK,PCDH18,PPP4R4,CACNG3,AASS,PTPRD,PLAG1,LSM11,PTPN21,NPM1,EPHB1,ZNF219,COLEC10,TNFRSF19,PCLO,MAP1A,APLF,PPFIBP1,GHR,NAP1L3,MET,IQGAP3,PTPRE,DNAH5,CHRM3,FER,DCC,KCNH5,PTPN13,TNS1,KHDRBS2,FGFR1,EBF1,PTPRC,ZNF711,TMEM132B,PTPRJ,PLAGL1,TERT,ADAMTS3,PTK7,PTPRS,PTPRN2,SLFN5,AMPD1 |
| 1.680e-03 | -6.39 | GO_COLLAGEN_BINDING | MSigDB lists | GO_COLLAGEN_BINDING | 60 | 14 | 17377 | 1707 |
SMAD3,PAK1,MRC2,MAP1A,FN1,ABI3BP,CCBE1,THBS4,ITGA2,CHADL,PCOLCE2,SERPINH1,COL14A1,DDR1 |
| 1.680e-03 | -6.39 | RNTCANNRNNYNATTW_UNKNOWN | MSigDB lists | RNTCANNRNNYNATTW_UNKNOWN | 60 | 14 | 17377 | 1707 |
FOXP2,ZNF827,LRRN1,MAP2,SAMD11,CHRDL1,NUAK2,INPP4B,JAKMIP2,FAR2,NRXN1,IKZF2,HEY1,MTUS1 |
| 1.681e-03 | -6.39 | TGF-beta signaling pathway | KEGG pathways | hsa04350 | 84 | 18 | 7161 | 730 |
NBL1,ID1,ACVR1,BMPR2,SMAD9,ACVR1C,ACVR2B,BMP6,ZFYVE9,SMAD3,ID3,INHBC,MYC,INHBE,ACVR2A,BMPR1A,BMP4,SMAD6 |
| 1.681e-03 | -6.39 | TGF-beta signaling pathway | KEGG pathways | ko04350 | 84 | 18 | 7161 | 730 |
NBL1,ID1,ACVR1,BMPR2,SMAD9,ACVR1C,ACVR2B,BMP6,ZFYVE9,SMAD3,ID3,INHBC,MYC,INHBE,ACVR2A,BMPR1A,BMP4,SMAD6 |
| 1.683e-03 | -6.39 | GO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | GO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 293 | 45 | 17377 | 1707 |
BTC,FARP1,ARHGEF11,DOCK1,PSD3,DOCK3,DENND3,DOCK2,TIAM2,ARHGEF10L,RALGPS2,MCF2L,NCAM1,DENND1C,RAPGEF5,GFRA1,RASGRP1,PDGFRB,DOCK8,FGFR4,VAV3,RIN2,MCF2L2,RAPGEF2,CYTH3,RAPGEF4,SPATA13,PREX1,OBSCN,FGF17,DOCK5,SERGEF,FGFR1,ARHGEF26,IRS2,DOCK7,RASGRF2,PLEKHG1,ADRB1,GRIN2D,IQSEC2,FNBP1L,DOCK6,DENND5B,DOCK9 |
| 1.687e-03 | -6.38 | organophosphate catabolic process | biological process | GO:0046434 | 155 | 27 | 17256 | 1658 |
PLA2G4A,NUDT10,GAPDH,PDE1B,PNP,ENO2,PFKFB2,OGDHL,PDE8A,NUDT12,ABHD6,INPP1,SMPDL3B,ENPP1,PRTFDC1,ENPP6,PDE10A,ALDOC,ALDOA,HK2,PGM2L1,INPP5F,HK1,PDE4D,ENO1,SMPDL3A,NUDT17 |
| 1.687e-03 | -6.38 | BILD_E2F3_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_E2F3_ONCOGENIC_SIGNATURE | 221 | 36 | 17377 | 1707 |
UGT8,ENO2,SCN8A,LRP4,CEBPA,ANKRD18A,PRRG4,KCTD15,SLC30A4,REEP1,RAB26,SREBF1,ZDHHC23,TRIM3,ATRNL1,PCOLCE2,TBC1D9,STXBP1,SMAD6,B4GALT6,FZD1,EML6,TMEM43,JPH1,AK4,PDE8A,CAMK2N1,MMP15,DDAH1,PKN3,SFMBT1,TMOD2,CMPK2,HEY1,HACE1,RRAGD |
| 1.687e-03 | -6.38 | V$TCF4_Q5 | MSigDB lists | V$TCF4_Q5 | 221 | 36 | 17377 | 1707 |
CGN,SORBS1,GABRB2,COL18A1,DOCK3,TNFRSF19,PGAP1,SP8,PCDH7,FOXP2,CHN2,PCBP4,SGK3,SHF,GAB2,PRDM13,PANK1,CYTH3,SLC25A28,FGF17,TCERG1L,STEAP1,RERE,DKK1,ZIC1,PRKCB,MAP2K6,PAM,ZBTB20,PPARGC1A,NKX2-8,LIFR,FOXA1,MME,PHC1,TLL2 |
| 1.695e-03 | -6.38 | HID1 (HID1 domain containing) | protein interactions | 283987 | 10 | 5 | 17029 | 1718 |
RCN3,PTPRN2,CBS,INPPL1,BEGAIN |
| 1.695e-03 | -6.38 | IFNE (interferon epsilon) | protein interactions | 338376 | 10 | 5 | 17029 | 1718 |
FAT4,TUBA1A,BACE2,FAT1,FRAS1 |
| 1.698e-03 | -6.38 | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | 386 | 56 | 17385 | 1698 |
TNIK,LATS2,MVK,MRC2,ACVR1,PLAG1,NPM1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,NEO1,SPEG,RPS6KA2,IGF1R,RPS6KL1,ACVR2A,SGK1,MET,SYK,FES,PDGFRB,PRKACB,PAK1,FGFR4,BCL7A,TNK2,PDK1,CRIM1,TGFA,AK4,CDC42BPA,ACVR2B,ATP1B1,PALLD,FGFR1,MAPKAPK2,CAMK2N1,AK1,TRIB3,FGR,PRKCB,PLK2,PTK7,AKT3,MAP2K6,HK2,MAPK13,ERCC5,PIK3C2B,BMPR1A,HK1,LIFR,DDIT3 |
| 1.698e-03 | -6.38 | salivary_gland-carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma | 386 | 56 | 17385 | 1698 |
TNIK,LATS2,MVK,MRC2,ACVR1,PLAG1,NPM1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,NEO1,SPEG,RPS6KA2,IGF1R,RPS6KL1,ACVR2A,SGK1,MET,SYK,FES,PDGFRB,PRKACB,PAK1,FGFR4,BCL7A,TNK2,PDK1,CRIM1,TGFA,AK4,CDC42BPA,ACVR2B,ATP1B1,PALLD,FGFR1,MAPKAPK2,CAMK2N1,AK1,TRIB3,FGR,PRKCB,PLK2,PTK7,AKT3,MAP2K6,HK2,MAPK13,ERCC5,PIK3C2B,BMPR1A,HK1,LIFR,DDIT3 |
| 1.698e-03 | -6.38 | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | 386 | 56 | 17385 | 1698 |
TNIK,LATS2,MVK,MRC2,ACVR1,PLAG1,NPM1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,NEO1,SPEG,RPS6KA2,IGF1R,RPS6KL1,ACVR2A,SGK1,MET,SYK,FES,PDGFRB,PRKACB,PAK1,FGFR4,BCL7A,TNK2,PDK1,CRIM1,TGFA,AK4,CDC42BPA,ACVR2B,ATP1B1,PALLD,FGFR1,MAPKAPK2,CAMK2N1,AK1,TRIB3,FGR,PRKCB,PLK2,PTK7,AKT3,MAP2K6,HK2,MAPK13,ERCC5,PIK3C2B,BMPR1A,HK1,LIFR,DDIT3 |
| 1.698e-03 | -6.38 | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | 386 | 56 | 17385 | 1698 |
TNIK,LATS2,MVK,MRC2,ACVR1,PLAG1,NPM1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,NEO1,SPEG,RPS6KA2,IGF1R,RPS6KL1,ACVR2A,SGK1,MET,SYK,FES,PDGFRB,PRKACB,PAK1,FGFR4,BCL7A,TNK2,PDK1,CRIM1,TGFA,AK4,CDC42BPA,ACVR2B,ATP1B1,PALLD,FGFR1,MAPKAPK2,CAMK2N1,AK1,TRIB3,FGR,PRKCB,PLK2,PTK7,AKT3,MAP2K6,HK2,MAPK13,ERCC5,PIK3C2B,BMPR1A,HK1,LIFR,DDIT3 |
| 1.698e-03 | -6.38 | upper_aerodigestive_tract-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-carcinoma | 386 | 56 | 17385 | 1698 |
TNIK,LATS2,MVK,MRC2,ACVR1,PLAG1,NPM1,CHUK,NTRK3,GRK6,PRKCA,DDR1,STK24,NEO1,SPEG,RPS6KA2,IGF1R,RPS6KL1,ACVR2A,SGK1,MET,SYK,FES,PDGFRB,PRKACB,PAK1,FGFR4,BCL7A,TNK2,PDK1,CRIM1,TGFA,AK4,CDC42BPA,ACVR2B,ATP1B1,PALLD,FGFR1,MAPKAPK2,CAMK2N1,AK1,TRIB3,FGR,PRKCB,PLK2,PTK7,AKT3,MAP2K6,HK2,MAPK13,ERCC5,PIK3C2B,BMPR1A,HK1,LIFR,DDIT3 |
| 1.700e-03 | -6.38 | GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 409 | 59 | 17377 | 1707 |
KCNV1,SCN5A,CACNG3,LGALS3,SCN8A,UBASH3B,GRK6,NRXN1,CACNB4,KCNC4,NEDD4,NOS1AP,KCNJ4,CA2,KCNN2,KCNAB1,AKAP7,SCN1B,CACNB2,KCNS3,TRPC1,TSPAN13,PDE4D,TMEM37,SCN2A,HSPA2,SCN3A,PDGFRB,KCNB2,DPP10,KCNIP3,GSTM2,KCNQ3,CACNA1E,KCNH5,ANK2,PTPN6,JPH1,FGF12,RYR2,GSTO1,CTTNBP2NL,KCND3,ATP1B1,AMIGO1,ASPH,SNCA,IRS2,KCNK15,CXCL10,KCNG1,BMP4,ATG5,PPARGC1A,TESC,ATP2B4,CACNA2D1,STOM,MEF2C |
| 1.708e-03 | -6.37 | DENND1A (DENN domain containing 1A) | protein interactions | 57706 | 78 | 17 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,SH3BP4,TANC2,KIF1B,OSBPL6,LARP1,GAB2 |
| 1.708e-03 | -6.37 | TMEM30B (transmembrane protein 30B) | protein interactions | 161291 | 78 | 17 | 17029 | 1718 |
FGFR4,TYRO3,PCDH10,TMEM67,PODXL2,CELSR3,CD276,C3orf52,PLXNA2,FGFR1,PCDH7,SEMA4F,C1QL4,TMEM143,ADGRL1,PTPRS,OCLN |
| 1.708e-03 | -6.37 | SCGB2A2 (secretoglobin family 2A member 2) | protein interactions | 4250 | 78 | 17 | 17029 | 1718 |
FGFR4,CHSY3,GXYLT2,UGT8,CEMIP2,CNTNAP3,SLC27A2,CHSY1,B4GALNT3,COL14A1,PPP1R9A,CHST10,HPSE,ERO1B,ERN1,SEMA3C,PCOLCE2 |
| 1.709e-03 | -6.37 | cytoplasmic vesicle | cellular component | GO:0031410 | 2278 | 255 | 18223 | 1724 |
DOC2A,EXPH5,CACNG3,PRSS12,SYT12,ATP8A1,DNAJC3,LDLR,VAMP8,MCOLN3,ITPR2,SNX9,DNER,SLC9A7,NCS1,PCDH7,TXNDC5,ADPRHL1,RND2,TM9SF2,SEC16B,ZFYVE28,HPS1,MARVELD2,RAP2A,ITGB3,RAB26,TMED9,PACSIN1,MYRIP,TLR4,CPE,PDGFRB,LAMP3,TNK2,CD55,SLC3A2,ABCC4,WLS,ANK2,TGFA,LRRK2,LRMP,COTL1,TRIM9,GSN,TMEM150B,GPRC5B,HPSE,NCKAP1L,ENTPD7,ATP7B,ALDOA,ADRB1,AHNAK2,SERPINI1,INPP5F,PIK3C2B,NRP1,APBA2,MAGI2,RRAGD,PCSK5,CHMP4C,SV2B,FN1,LGALS3,RHOBTB1,SEC24D,GABRB2,SCN8A,ATP6V1E2,APBA1,DYNC1I1,SPINK5,MLC1,SPIRE1,MCOLN2,EEF2,SLC30A4,ABCA5,BACE2,SREBF1,LRP6,GRIP1,LMAN2,MPDZ,CADPS2,SLCO4C1,DENND1C,MOXD1,AGL,STXBP1,CKAP4,GPR161,SNX7,NOS3,FGFR4,BDNF,QSOX1,RHOQ,PNP,SLC27A2,FASN,PACSIN3,RYR2,HIP1,CALCRL,NPC2,SNAP25,RABAC1,ARRDC4,STEAP1,TMEM74,BAIAP2,TBC1D2,VPS37D,SH3GL2,FCHO2,PMEPA1,SH3BP4,RAB31,PTPRN2,LAPTM4B,PLD1,FNBP1L,MME,SFN,PLA2G4A,EPHA3,DMXL2,FRMPD3,PRKN,DNM3,AMOTL1,PCSK1N,SCAMP1,IL15,RHOD,RNF144A,MYO1B,MSR1,RGS20,ADD2,CANX,KIF21B,DOCK2,ZFYVE9,CD53,CCDC120,GPR15,TLR3,ERG28,UNC13B,ALDOC,STARD4,DAB2IP,STEAP3,PROS1,RAB27B,SYNGR3,CLVS2,SNX10,GCA,ANTXR2,EVL,GARS,TMEM67,TUBA1A,FZD4,PTPN6,PANK1,VIM,RARRES2,RAB38,DSP,TBC1D16,FRK,FGFR1,GABARAPL1,SNCA,ARHGAP21,PTPRJ,PAM,PTPRS,HGF,ATG5,SEPT5,CTTNBP2,STON2,ARFGEF3,TNIK,MYO1D,ANKRD13B,ANKRD13D,LPAR2,PRSS16,TSPAN15,GRB14,GLIPR1L1,RUSC2,BACE1,ATP9A,GABRG2,SELL,GAS6,PKN1,EPHB1,NDFIP2,SELENOP,ARHGAP44,RAB11FIP5,KCNJ4,RGS17,TECPR1,PRKCD,EHD3,KIAA0319,SGK3,MARCH3,TRIM3,MORN2,FIG4,MYO6,ESD,SYK,FES,VEGFC,SLC40A1,RAB3B,RAB6B,RAPGEF2,SYBU,LITAF,PHACTR2,ARHGAP32,ATP11A,FNDC3A,TLR6,LRAT,DKK1,PTPRC,FGR,ICA1,RND3,PRCP,CTSV,SLC1A5,TBC1D4,KIF1B,DDIT3,OCLN,ABCG1,TPT1,STOM |
| 1.712e-03 | -6.37 | GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | 80 | 17 | 17377 | 1707 |
PFKFB4,AK1,GAPDH,ENO2,PFKFB2,ALDOC,MPP1,ALDOA,MPP2,OGDHL,HK2,AK4,DLG2,HK1,CMPK2,ENO1,MAGI3 |
| 1.713e-03 | -6.37 | V$ZIC2_01 | MSigDB lists | V$ZIC2_01 | 237 | 38 | 17377 | 1707 |
CCDC148,ANKRD13B,FLVCR2,FGF13,REL,GABRG2,CADM2,CYP26A1,COL27A1,MTUS1,NELL2,MAP1A,GHR,TMEM132E,FES,ZNF385A,SEMA6C,GLI1,NDUFA4L2,PTCH2,PCDH10,BDNF,GPM6A,SESN2,USP2,RAB6B,ZDHHC15,FGF12,PLXDC2,GNAO1,PTK7,PCGF2,GRIN2D,HOXD13,LRRK1,NKX2-8,HOXB9,MAPK10 |
| 1.716e-03 | -6.37 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_UP | 137 | 25 | 17377 | 1707 |
TRIM2,CFH,RHOBTB1,STXBP6,EPS8,FHL2,PSD3,CTTNBP2NL,SPATS2L,CDC42BPA,TSPAN17,FGFR1,TPK1,PCDH7,ATXN7L1,RNF141,SERINC2,TMEM117,ACVR2A,TSPAN12,NIPAL2,PCK2,STOM,B4GALT6,MEF2C |
| 1.716e-03 | -6.37 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | 190 | 32 | 17377 | 1707 |
MYCBP2,PRSS12,GATA3,SELL,NPM1,KCTD12,CD7,SATB1,SKI,RNF141,MCOLN2,SIPA1L2,MYC,EIF1,ZFP36L2,DUSP1,EVL,SLC3A2,PNRC1,PDK1,GSTO1,PLEKHA1,RABAC1,TLR6,SESN1,RERE,PAM,RGS10,ERCC5,ZBTB20,LARP1,ABCG1 |
| 1.716e-03 | -6.37 | GSE24574_NAIVE_VS_TCONV_CD4_TCELL_UP | MSigDB lists | GSE24574_NAIVE_VS_TCONV_CD4_TCELL_UP | 190 | 32 | 17377 | 1707 |
RPS20,MAN2B2,DNM3,ID1,ARHGEF11,ITGA6,PLXNA2,SORBS3,COL14A1,PHLDA2,DDIT4,SPEG,MCF2L,FAM168A,ZFP36L2,DLGAP1,TNK2,VNN2,TUBA1A,RASA3,ACVR2B,PRDM1,ISG20,BCL11A,CD37,MCC,NXPH4,HPGD,TANC2,CDH2,MMP16,DDIT3 |
| 1.716e-03 | -6.37 | GSE18893_TCONV_VS_TREG_24H_CULTURE_UP | MSigDB lists | GSE18893_TCONV_VS_TREG_24H_CULTURE_UP | 190 | 32 | 17377 | 1707 |
ITGB7,GDAP1,RAB3B,TCP11L2,LGALS3,EBPL,RHOBTB1,ST6GAL1,CYTH3,CRIP2,LITAF,ASS1,RASA3,PDE8A,TJP1,VIM,SFXN3,LCP2,ADSSL1,NEO1,MCU,SLC7A1,MYADM,AHNAK2,RCN3,SGK1,TBC1D9,LIFR,NR3C2,SMPDL3A,CKAP4,B4GALT6 |
| 1.716e-03 | -6.37 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | 190 | 32 | 17377 | 1707 |
MICAL2,TUBA1A,ABCC4,ST14,TBC1D1,ST6GAL1,XYLT1,HOMER2,LRMP,PPFIBP2,KIF5C,TGDS,PALLD,SATB1,RNF44,SEL1L3,MAP1B,QPRT,BEX4,ID3,SYCP2,HLF,PRCP,MAOA,LAPTM4B,TPM1,SPRY2,ATP2B1,FES,LAMP3,PCSK5,ABCG1 |
| 1.716e-03 | -6.37 | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN | MSigDB lists | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_DN | 190 | 32 | 17377 | 1707 |
CREB3L2,BCL11B,PHACTR3,TCP11L2,AKAP5,ELOVL7,MSR1,KCTD12,PRKCA,RBM11,CBLN1,TRPS1,RAB11FIP5,FBXO32,MARCH3,MARCKS,FHIT,KLHL29,KCNIP3,WLS,YAP1,SMARCD3,ATP10D,NAP1L5,KLF12,BACH2,SERPINI1,ZBTB20,KIF1B,MLLT3,DDIT3,ABCG1 |
| 1.716e-03 | -6.37 | GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN | MSigDB lists | GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN | 190 | 32 | 17377 | 1707 |
CREB3L2,MAN2B2,TUBA1A,ENO2,RHOD,CAP2,LRP4,SYBU,DEPTOR,BEGAIN,HERC5,GABRR2,RABAC1,ROR1,HERC6,PALLD,EML1,HOMER3,NKX6-1,DEXI,GPRC5B,NACC2,MPP2,MARCKS,PCOLCE2,SYNGR3,DHCR7,HSPA2,FOXA1,IGSF3,PCSK5,LAMP3 |
| 1.716e-03 | -6.37 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP | 190 | 32 | 17377 | 1707 |
CREB3L2,CARD6,VAV3,SEMA6B,PDK1,ALOX5AP,PNP,RNF144A,KLHL23,WLS,SPATA6,BNIP3L,SNX9,KREMEN1,SLC19A2,DDX60L,NEDD4,STK24,TRPS1,CEBPB,TRIB3,ZDHHC6,HK2,TSC22D1,DAB2IP,NAP1L3,JAKMIP2,CAB39L,PJA1,MET,ATP2B1,FZD1 |
| 1.716e-03 | -6.37 | GSE3982_DC_VS_NKCELL_UP | MSigDB lists | GSE3982_DC_VS_NKCELL_UP | 190 | 32 | 17377 | 1707 |
FN1,LGALS3,ARHGAP22,NDRG2,IL13RA1,SCD,CREB5,ABHD6,PPP2R3A,ARHGEF10L,TMEM53,KMO,SGK1,CTTN,ESD,STXBP1,TBC1D8,PPP1R3D,FHL2,AK4,ATF3,TNS1,ASPH,CPEB1,GSN,P4HA2,CSF1,CCNA1,RAB31,MAOA,NRP1,IQSEC2 |
| 1.716e-03 | -6.37 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 190 | 32 | 17377 | 1707 |
EFNB2,QSOX1,USP2,COL6A2,UROS,CFH,PDE1B,RECK,PLEKHA5,ATP9A,SPATA6,RAPGEF4,SDC3,NTRK3,IKZF2,SLCO3A1,BMP6,STK24,RERE,RPL12,SLC7A11,OSBPL5,ITGB3,PRKCD,ADCY6,LAPTM4B,ZBTB20,CMPK2,BTRC,TPT1,ABCG1,PHC1 |
| 1.716e-03 | -6.37 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | 190 | 32 | 17377 | 1707 |
SUSD3,CREB3L2,PFKFB4,TRPM4,RHOQ,SKAP2,TMEM43,MYO10,MCTP2,BNIP3L,VIM,FNDC3A,DDR1,DACH2,CA13,SLC39A14,EBF1,KIAA1958,SEMA4F,CPVL,SH3RF1,MAP2K6,C1orf21,RAB26,BEND4,DLG2,GEM,RAPGEF5,GATM,MED12L,DDIT3,STOM |
| 1.716e-03 | -6.37 | GSE3982_DC_VS_BCELL_UP | MSigDB lists | GSE3982_DC_VS_BCELL_UP | 190 | 32 | 17377 | 1707 |
FN1,GALNT12,DHCR24,ABHD6,PPP2R3A,ARHGEF10L,TMEM53,TGFBR3,RAP2A,IPCEF1,SPRY2,CTH,PGBD5,PPP1R3D,MICAL2,ALDH2,MYO10,MPP1,ACO1,ATF3,TNS1,PHACTR2,PALLD,FAM162A,CEBPB,P4HA2,RAB31,AHNAK2,TNFRSF1A,MAOA,NRP1,CSRP2 |
| 1.716e-03 | -6.37 | GSE29618_MONOCYTE_VS_PDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_UP | 190 | 32 | 17377 | 1707 |
SERINC5,RIN2,GAPDH,ACSL1,PXN,LGALS3,IL15,HEBP1,BLVRB,BNIP3L,MAFB,CEBPA,FAM198B,CREB5,CHSY1,SLCO3A1,PTPRC,IRS2,ENTPD1,EPB41L3,FGR,HPSE,NACC2,BCL6,RAB31,HK2,LIN7A,MARCKS,TLR4,CKAP4,PCSK5,CYP1B1 |
| 1.722e-03 | -6.36 | alveolar | COSMIC cancer mutations | alveolar | 2466 | 282 | 17385 | 1698 |
SIDT1,GRIK2,PRSS12,LDLR,NPM1,CTBP2,CEBPA,AARS,SKI,TRPS1,EPDR1,BAG3,TGFBR3,DNAH6,PPFIA2,RAB26,KCNS3,GSTM3,PPP2R2B,TBC1D8,ACVR1C,DCC,KLHL23,KLHL4,LRRK2,NFIA,ABCC2,GPR150,ENPP1,PLK2,ERCC5,DSEL,TANC2,DNHD1,SPOCK3,SCN5A,TMEM63C,INPPL1,FAM124A,CELSR1,ZHX3,TBC1D1,ITGA6,ZNF25,TJP1,SLC1A3,WDFY4,MTUS1,KIAA1671,FAM189A1,VWDE,OPN3,LMAN2,ALPK1,LOXL4,MOXD1,ZNF518B,FMNL2,HMGCR,SLC37A1,PNP,MYO10,COL4A4,FASN,KIAA1324L,RYR2,SMARCD3,CDC42BPA,CLN5,DAGLA,TEX15,GSTO2,THBS4,CECR2,AMPD1,DOCK9,PLA2G4A,TBKBP1,ZNF516,ELOVL4,RNF144A,GALNT12,ZNF311,MSR1,RGS20,ADD2,KCTD12,TBC1D30,TIAM2,NELL2,ZNF827,SPEG,TLR3,CHRNA5,GPRIN1,POU5F1B,DNAH5,FZD1,GAB2,GARS,COL6A2,GAPDH,PRKCQ,TTC28,ATP10D,FGFR1,ENTPD1,WFS1,LAMB1,PAM,PLEKHG1,FAM149A,KLF5,KLHL31,LRRC27,COBL,PURG,ANKRD13D,WDR17,ROBO2,ESRP1,CD276,COL27A1,NEDD4,NEO1,LRRC55,MGAT1,NPTXR,GFI1,MED12L,MN1,BCL7A,VAV3,PTPN13,UCHL3,HEG1,ZFP62,NSD1,PLOD2,TERT,XBP1,DOCK6,PHC1,SYT12,FHDC1,LILRB1,SLC2A13,FAM13A,DNER,HMCN1,FKBP11,CYP51A1,ARHGEF10L,RTN1,CPVL,TLN2,NEB,IL1RAP,CYP1B1,CD55,MARK1,COL4A3,ABCC4,CAPN5,YAP1,SERGEF,CRYBG3,DYRK1B,TCF7L1,HPSE,MAP2,P4HA2,TNFRSF1A,PIK3C2B,OXTR,PPARGC1A,APBA2,TC2N,STXBP5L,LGALS3,SCART1,GALNT13,SCD,MLC1,CD7,FHOD3,ZBTB38,KIAA0895,IGF1R,ZNF440,BCHE,FRAS1,GAN,LRP6,LRP3,NOS3,CDH26,HBG2,IL17RD,MSTN,PARD3B,EDEM3,SPATA13,SLITRK5,OBSCN,SDC3,PDE8A,SDK1,FAT1,HK2,PLD1,DISP2,DMXL2,CXCR5,EML5,SORBS1,ID1,CELSR3,DOCK1,COBLL1,COL18A1,MORC4,ZNF83,SLC7A2,CANX,PCLO,CYP26A1,FAM131B,COL22A1,SLC22A17,PDZD8,TACC2,EEPD1,MYH15,STEAP3,MET,SP140L,SEMA6C,IGFBP3,TMEM65,TES,ACO1,RNF125,VIM,GSTO1,CENPV,C4BPB,TMPRSS9,ITGA2,MAOA,HGF,DISP1,DYRK3,GRB14,LRP4,COL4A5,NOTUM,TECPR1,SCN1B,TSC22D1,KIAA0319,PRICKLE2,IQGAP3,CES3,LRRIQ1,NR4A1,ASAP3,LITAF,MEI1,AGAP2,ZFPM2,NPDC1,LEPR,MGMT,SMPDL3B,RERE,EBF1,ADAMTS17,FBN1,THSD7B,ZNF474,TBC1D4 |
| 1.722e-03 | -6.36 | soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-alveolar | 2466 | 282 | 17385 | 1698 |
SIDT1,GRIK2,PRSS12,LDLR,NPM1,CTBP2,CEBPA,AARS,SKI,TRPS1,EPDR1,BAG3,TGFBR3,DNAH6,PPFIA2,RAB26,KCNS3,GSTM3,PPP2R2B,TBC1D8,ACVR1C,DCC,KLHL23,KLHL4,LRRK2,NFIA,ABCC2,GPR150,ENPP1,PLK2,ERCC5,DSEL,TANC2,DNHD1,SPOCK3,SCN5A,TMEM63C,INPPL1,FAM124A,CELSR1,ZHX3,TBC1D1,ITGA6,ZNF25,TJP1,SLC1A3,WDFY4,MTUS1,KIAA1671,FAM189A1,VWDE,OPN3,LMAN2,ALPK1,LOXL4,MOXD1,ZNF518B,FMNL2,HMGCR,SLC37A1,PNP,MYO10,COL4A4,FASN,KIAA1324L,RYR2,SMARCD3,CDC42BPA,CLN5,DAGLA,TEX15,GSTO2,THBS4,CECR2,AMPD1,DOCK9,PLA2G4A,TBKBP1,ZNF516,ELOVL4,RNF144A,GALNT12,ZNF311,MSR1,RGS20,ADD2,KCTD12,TBC1D30,TIAM2,NELL2,ZNF827,SPEG,TLR3,CHRNA5,GPRIN1,POU5F1B,DNAH5,FZD1,GAB2,GARS,COL6A2,GAPDH,PRKCQ,TTC28,ATP10D,FGFR1,ENTPD1,WFS1,LAMB1,PAM,PLEKHG1,FAM149A,KLF5,KLHL31,LRRC27,COBL,PURG,ANKRD13D,WDR17,ROBO2,ESRP1,CD276,COL27A1,NEDD4,NEO1,LRRC55,MGAT1,NPTXR,GFI1,MED12L,MN1,BCL7A,VAV3,PTPN13,UCHL3,HEG1,ZFP62,NSD1,PLOD2,TERT,XBP1,DOCK6,PHC1,SYT12,FHDC1,LILRB1,SLC2A13,FAM13A,DNER,HMCN1,FKBP11,CYP51A1,ARHGEF10L,RTN1,CPVL,TLN2,NEB,IL1RAP,CYP1B1,CD55,MARK1,COL4A3,ABCC4,CAPN5,YAP1,SERGEF,CRYBG3,DYRK1B,TCF7L1,HPSE,MAP2,P4HA2,TNFRSF1A,PIK3C2B,OXTR,PPARGC1A,APBA2,TC2N,STXBP5L,LGALS3,SCART1,GALNT13,SCD,MLC1,CD7,FHOD3,ZBTB38,KIAA0895,IGF1R,ZNF440,BCHE,FRAS1,GAN,LRP6,LRP3,NOS3,CDH26,HBG2,IL17RD,MSTN,PARD3B,EDEM3,SPATA13,SLITRK5,OBSCN,SDC3,PDE8A,SDK1,FAT1,HK2,PLD1,DISP2,DMXL2,CXCR5,EML5,SORBS1,ID1,CELSR3,DOCK1,COBLL1,COL18A1,MORC4,ZNF83,SLC7A2,CANX,PCLO,CYP26A1,FAM131B,COL22A1,SLC22A17,PDZD8,TACC2,EEPD1,MYH15,STEAP3,MET,SP140L,SEMA6C,IGFBP3,TMEM65,TES,ACO1,RNF125,VIM,GSTO1,CENPV,C4BPB,TMPRSS9,ITGA2,MAOA,HGF,DISP1,DYRK3,GRB14,LRP4,COL4A5,NOTUM,TECPR1,SCN1B,TSC22D1,KIAA0319,PRICKLE2,IQGAP3,CES3,LRRIQ1,NR4A1,ASAP3,LITAF,MEI1,AGAP2,ZFPM2,NPDC1,LEPR,MGMT,SMPDL3B,RERE,EBF1,ADAMTS17,FBN1,THSD7B,ZNF474,TBC1D4 |
| 1.724e-03 | -6.36 | TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition | WikiPathways | WP3859 | 18 | 7 | 5312 | 569 |
SMAD3,VIM,ID1,RUNX2,FN1,CDH2,SNAI2 |
| 1.731e-03 | -6.36 | Hippo signaling pathway -multiple species | KEGG pathways | hsa04392 | 29 | 9 | 7161 | 730 |
MOB1B,PAK1,LATS2,FAT4,WWTR1,DCHS1,WWC1,YAP1,SAV1 |
| 1.731e-03 | -6.36 | Hippo signaling pathway -multiple species | KEGG pathways | ko04392 | 29 | 9 | 7161 | 730 |
MOB1B,PAK1,LATS2,FAT4,WWTR1,DCHS1,WWC1,YAP1,SAV1 |
| 1.733e-03 | -6.36 | GSE45365_WT_VS_IFNAR_KO_CD11B_DC_DN | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_CD11B_DC_DN | 152 | 27 | 17377 | 1707 |
GAPDH,MSTN,TBC1D8B,CHCHD7,MYO10,C1orf226,RASL11B,GALNT13,VIM,INTS6,RBM11,FRK,FAM110B,PEAK1,NEDD4,TEX15,LRRC6,L3MBTL4,MAP2K6,PRKCD,LIN7A,PLD1,FIG4,PCOLCE2,LOXL4,SMPDL3A,DIRC2 |
| 1.734e-03 | -6.36 | NADH regeneration | biological process | GO:0006735 | 25 | 8 | 17256 | 1658 |
GAPDH,ENO2,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1 |
| 1.734e-03 | -6.36 | glucose catabolic process to pyruvate | biological process | GO:0061718 | 25 | 8 | 17256 | 1658 |
GAPDH,ENO2,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1 |
| 1.734e-03 | -6.36 | canonical glycolysis | biological process | GO:0061621 | 25 | 8 | 17256 | 1658 |
GAPDH,ENO2,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1 |
| 1.746e-03 | -6.35 | FCH | smart domains | SM00055 | 22 | 8 | 9493 | 1056 |
FER,PACSIN1,FNBP1L,FCHO2,PSTPIP2,FES,PACSIN3,SRGAP1 |
| 1.747e-03 | -6.35 | NCAM1 interactions | REACTOME pathways | R-HSA-419037 | 37 | 10 | 10287 | 971 |
COL9A3,COL6A2,COL4A3,CACNB2,COL4A4,COL4A5,NCAM1,CACNB4,GFRA1,COL9A2 |
| 1.749e-03 | -6.35 | SASSON_RESPONSE_TO_FORSKOLIN_DN | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_DN | 87 | 18 | 17377 | 1707 |
TYRO3,DYRK3,TUBA1A,RASAL2,ATP9A,CAP2,NPC2,STK24,ABLIM1,PDLIM3,PMAIP1,GBP1,RAB31,SH3BP4,ACTA2,GEM,TPM1,PTPRE |
| 1.752e-03 | -6.35 | muscle system process | biological process | GO:0003012 | 300 | 45 | 17256 | 1658 |
SCN5A,SORBS1,IL15,ARHGEF11,PKP2,SORBS3,CHUK,P2RY1,EEF2,KCNN2,SCN1B,CACNB2,PRKG1,SMTN,ACTA2,PDE4D,GATM,NEB,CHRM3,NOS3,GSTM2,PXN,MSTN,ANK2,FGF12,RYR2,VIM,KCND3,ATP1B1,SNTB1,ASPH,GJC1,HTR7,GSN,MAP2K6,GNAO1,ALDOA,MYOM2,TMOD2,INPP5F,OXTR,TPM1,PPARGC1A,CACNA2D1,MEF2C |
| 1.754e-03 | -6.35 | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_UP | 198 | 33 | 17377 | 1707 |
SCN5A,FN1,ZCCHC24,MSR1,SLC1A3,LACC1,COL14A1,COL27A1,ASNS,ABI3BP,SERPINH1,MOXD1,GFRA1,CKAP4,VEGFC,DLGAP1,SLC40A1,ANTXR2,PRICKLE1,C1R,KCND3,CTTNBP2NL,SLC46A3,HOMER3,RPL12,FBN1,PLK2,PAM,PGM2L1,HGF,VASH2,TPM1,OCLN |
| 1.756e-03 | -6.34 | GO_SYNAPTIC_VESICLE_LOCALIZATION | MSigDB lists | GO_SYNAPTIC_VESICLE_LOCALIZATION | 101 | 20 | 17377 | 1707 |
DOC2A,SYT12,OPHN1,SNAP25,CANX,NRXN1,SYT14,PCLO,SNCA,TRIM9,SH3GL2,UNC13B,LIN7A,CADPS2,PACSIN1,SEPT5,TC2N,STON2,RIMS2,SNPH |
| 1.758e-03 | -6.34 | nucleoside diphosphate phosphorylation | biological process | GO:0006165 | 55 | 13 | 17256 | 1658 |
AK1,GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,OGDHL,HK2,PGM2L1,AK4,HK1,CMPK2,ENO1 |
| 1.761e-03 | -6.34 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 1819 | 215 | 17377 | 1707 |
ACVR1,LGR4,TRIM16,VAMP8,LMCD1,GATA3,LILRB1,STAT5B,CTBP2,ABAT,PRKCA,CACNB4,NOS1AP,F3,SKI,TGFBR3,PMAIP1,CFHR1,ITGB3,HRK,TLR4,SLIT2,PRKACB,RASGRP1,PDGFRB,CYP1B1,GCNT2,CD55,SKAP2,WLS,TGFA,LRRK2,BNIP3L,YAP1,CR2,ACVR2B,PLEKHA1,F12,INHBC,GSN,HPSE,GPRC5B,NCKAP1L,WIPF3,CCBE1,PLK2,ERN1,TNFRSF1A,BMP1,ADRB1,BBC3,MAPK13,DIRAS1,TMOD2,UNC5B,TNFSF4,NRP1,MLLT3,MEF2C,RRAGD,PRKAA2,FN1,SORBS3,CHSY1,TNFRSF19,CHD5,IL18R1,CHN1,PIK3AP1,MYC,LRP6,BNIP3,RIMS2,ZNF385A,HMGCR,PAK1,FGFR4,MID2,BDNF,DISC1,MSTN,SH2D2A,MYO10,DUSP9,WWC1,C1R,PLCB1,FAM162A,HERPUD1,BAIAP2,MAPKAPK2,ADAMTS3,CSF1,PELI2,THBS4,INHBE,TRPC3,CDH2,SFN,PLA2G4A,NEK10,AVPI1,SORBS1,CFH,IL15,AKAP5,DOCK1,C4A,CHUK,NTRK3,COLEC10,LCP2,NRXN1,PIBF1,TLR3,UNC13B,DACT1,ACVR2A,DAB2IP,MARCKS,PDE4D,MET,CTH,GLI1,IGFBP3,GAB2,INTU,FZD4,PTPN6,PRKCQ,GSTO1,WNT11,ATF3,SYNJ2BP,RARRES2,CD40,ASPH,C4BPB,FGFR1,SNCA,SMAD3,CXCL10,PTPRJ,PRKCB,ITGA2,DUSP19,GRB10,HGF,TNFSF15,DISP1,BMPR1A,ATG5,SUSD4,MAPK10,MID1,TNIK,BMPR2,EDA2R,GRB14,TSPAN15,REL,FZD8,APBB1,EPS8,BIK,GAS6,P2RY1,NDFIP2,PKN1,TPD52L1,BMP6,TSPAN17,NEDD4,PPP2R3A,HOPX,NEO1,CHN2,MCF2L,RASD2,GHR,PRKCD,AFAP1L2,DYNC2H1,IQGAP3,GFI1,TNFRSF11A,SPRY2,SYK,VEGFC,TRPM4,VAV3,MSX1,SH3BP2,GSTM2,RAPGEF2,LITAF,SKAP1,TLR6,MGMT,GPLD1,GPR37,PTPRC,FGR,NACC2,MPP7,TERT,MAP2K6,XBP1,BMP4,LRRK1,SHOX2,LARP1,DDIT3,BTRC,FOXA1 |
| 1.764e-03 | -6.34 | GO_PHOSPHATIDYLINOSITOL_3_KINASE_BINDING | MSigDB lists | GO_PHOSPHATIDYLINOSITOL_3_KINASE_BINDING | 30 | 9 | 17377 | 1707 |
IRS2,TYRO3,IGF1R,PIK3AP1,PTPN13,XBP1,DAB2IP,FBXL2,PDGFRB |
| 1.767e-03 | -6.34 | C5 isoprenoid biosynthesis, mevalonate pathway | KEGG pathways | M00095 | 10 | 5 | 7161 | 730 |
MVK,IDI1,HMGCS1,MVD,HMGCR |
| 1.767e-03 | -6.34 | C5 isoprenoid biosynthesis, mevalonate pathway | KEGG pathways | hsa_M00095 | 10 | 5 | 7161 | 730 |
MVK,IDI1,HMGCS1,MVD,HMGCR |
| 1.767e-03 | -6.34 | Activin signaling | KEGG pathways | hsa_M00681 | 10 | 5 | 7161 | 730 |
SMAD3,ACVR2A,INHBC,ACVR2B,INHBE |
| 1.767e-03 | -6.34 | Activin signaling | KEGG pathways | M00681 | 10 | 5 | 7161 | 730 |
SMAD3,ACVR2A,INHBC,ACVR2B,INHBE |
| 1.767e-03 | -6.34 | DUSP10 (dual specificity phosphatase 10) | protein interactions | 11221 | 24 | 8 | 17029 | 1718 |
ACTA2,SLX1B,IGF1R,FN1,MAPK10,PTK7,RPS11,FHL2 |
| 1.775e-03 | -6.33 | potassium channel regulator activity | molecular function | GO:0015459 | 48 | 12 | 17224 | 1680 |
DPP10,KCNV1,LRRC55,KCNIP3,KCNMB4,KCNAB1,KCNMB3,KCNS3,SGK3,SGK1,AMIGO1,SGK2 |
| 1.785e-03 | -6.33 | V$LBP1_Q6 | MSigDB lists | V$LBP1_Q6 | 206 | 34 | 17377 | 1707 |
NDUFA4L2,BCL7A,LRFN5,TUBA1A,IGFBP6,ZCCHC24,STXBP6,SPATA6,PACSIN3,GATA3,SLITRK5,PRICKLE1,NOVA1,MBNL2,DDIT4,FGR,SLC22A17,DACT1,CACNB2,B3GALT2,MPPED2,NBEA,SVIL,NXPH4,DLG2,BNIP3,LOXL4,VWA5A,DNHD1,GFI1,KIF1B,ZNF385A,DOCK9,GAB2 |
| 1.788e-03 | -6.33 | GO_METAL_ION_TRANSPORT | MSigDB lists | GO_METAL_ION_TRANSPORT | 555 | 76 | 17377 | 1707 |
CACNG3,MCOLN3,ITPR2,CACNB4,NCS1,SLC9A7,KCNN2,KCNAB1,SLC10A7,KCNS3,TRPC1,CNNM2,STEAP3,TMEM37,SCN2A,SCN3A,KCNB2,GPM6A,SLC3A2,KCNIP3,CSN2,KLHL3,SLC39A8,KCNH5,ANK2,JPH1,ATOX1,ATP1B1,KCND3,ASPH,SFXN1,SLC39A14,KCNMB4,PRKCB,ATP7B,KCNG1,BBC3,SLC9B1,DENND5B,KCNV1,SCN5A,SCN8A,ATP6V1E2,SLC12A6,GAS6,NDFIP2,KCNC4,MCU,MCOLN2,KCNJ4,SLC30A4,SCN1B,CACNB2,BHLHA15,KCNMB3,SGK1,SLC6A15,NIPAL2,ATP2B1,TRPM4,SLC40A1,KCNQ3,CACNA1E,RASA3,CALCRL,RYR2,STEAP1,PTPRC,KCNK15,CACHD1,TRPC3,CACNA2D1,ATP2B4,DDIT3,ATP1A3,TPT1 |
| 1.797e-03 | -6.32 | AMIT_SERUM_RESPONSE_240_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_240_MCF10A | 54 | 13 | 17377 | 1707 |
LRRC8B,GBP1,TGFA,ITGA2,XBP1,PKP2,TJP1,PHLDA2,OCLN,HERPUD1,PGBD5,DKK1,PCDH7 |
| 1.797e-03 | -6.32 | GO_L_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_L_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 54 | 13 | 17377 | 1707 |
SLC7A1,SERINC5,SLC6A9,SLC7A11,SLC36A1,SLC7A5,SERINC2,SLC36A4,SLC6A15,SLC7A2,SLC1A3,SLC1A5,SLC43A1 |
| 1.801e-03 | -6.32 | sodium channel regulator activity | molecular function | GO:0017080 | 36 | 10 | 17224 | 1680 |
FGF13,SCN1B,SGK3,FGF12,SGK1,PKP2,SGK2,NEDD4,ATP2B4,GPLD1 |
| 1.801e-03 | -6.32 | CTTTGTA,MIR-524 | MSigDB lists | CTTTGTA,MIR-524 | 410 | 59 | 17377 | 1707 |
EPHA3,MXI1,LGR4,CELSR3,DOCK1,CNTNAP3,KIF5A,ATP8A1,YPEL2,TJP1,GPR180,ADAMTS6,SLC1A3,ABHD4,TNKS1BP1,PFN2,COL14A1,SP8,TRPS1,SIPA1L2,CPNE2,DLX6,LHX6,NBEA,PTPRE,ATP2B1,DBN1,SSH3,VAV3,GPM6A,KCNQ3,PTPRU,PTPN13,FOXN3,STAT4,GRID1,NFIA,PRICKLE1,PRDM1,TCERG1L,SESN1,MBNL2,ZIC1,GNAI1,SMAD3,IRS2,ZNF711,IGIP,GNAO1,P4HA2,PCGF2,RAI14,TUFT1,HOXD13,SPRY4,FNBP1L,LARP1,CRISPLD1,MEF2C |
| 1.805e-03 | -6.32 | acral_lentiginous | COSMIC cancer mutations | acral_lentiginous | 761 | 99 | 17385 | 1698 |
EXPH5,PLA2G4A,PAGE1,TCP11L2,SIDT1,KIF5A,ARHGAP22,RGS20,RHPN2,PKP2,CADM2,COL14A1,SLCO3A1,ADPRHL1,NELL2,SPEG,MPPED2,JAKMIP2,MYH15,COG3,MET,TLN2,VWA5A,TSHR,IL1RAP,KCNB2,SCN3A,INTU,PHLDB2,COL6A2,ABCC4,CSN2,COL4A3,DCC,FZD4,KCNH5,NLGN4X,TNS1,FGFR1,GPC6,TPK1,WARS,ZNF93,NRG3,IQCH,MAP2,NCAM2,NCKAP1L,WFS1,GPR160,ARHGAP28,CYP2U1,MAST1,ANKRD13D,CELSR1,STXBP5L,GCAT,ELOVL7,GTF2IRD1,SETBP1,RASL11B,ZNF215,ADSSL1,TSPAN17,PPP2R3A,FHOD3,NUMBL,MAP1A,FRY,STC2,GAN,PRICKLE2,LIMCH1,ALPK1,LOXL4,FIG4,RIMS2,ALDH2,GSTM2,LRRIQ1,COL4A4,FERMT2,ARHGAP32,GUCY1A2,PLCB1,ZIC1,GPLD1,PTPRC,TMCO3,FAT4,TERT,PKN3,L3MBTL4,PTPRN2,NEK11,PGM2L1,OSBPL6,SMYD3,DCBLD1 |
| 1.813e-03 | -6.31 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | 160 | 28 | 17377 | 1707 |
DOCK1,RBFOX2,APBB1,LRMP,HIP1,ENAH,TJP1,KIF21B,TAF4B,PFN2,CD53,TXNRD3,PLS3,PTPRC,FKBP9,NCKAP1L,PCBP4,MYC,PLK2,WWTR1,LAMB1,PCGF2,SH3BP4,ADCY6,LAPTM4B,CTTN,MID1,LPP |
| 1.813e-03 | -6.31 | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_DN | MSigDB lists | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_DN | 160 | 28 | 17377 | 1707 |
TNIK,CD55,PDK1,ST6GAL1,ITGA6,RAPGEF4,SELL,TDRKH,PLEKHA1,SESN1,MAGI3,ID3,HMGCS1,RALGPS2,PLXDC2,MYC,INPP4B,RGS10,KCNMB3,ADCY6,TOX,IPCEF1,ST8SIA1,RRAS2,SLFN5,AMPD1,CSRP2,DIRC2 |
| 1.813e-03 | -6.31 | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | 160 | 28 | 17377 | 1707 |
THOC5,PDK1,KDM5B,TDRD3,PLAG1,SPATA6,CALCRL,PRKAR2B,WDFY4,FNDC3A,NEDD4,TBC1D19,TRPS1,TTC1,CPNE2,TIFA,IGF1R,PLOD2,CACNB2,TSC22D1,RALGAPA2,SVIL,ZBTB20,ALPK1,IPCEF1,FBXO27,ZFP36L2,KCTD1 |
| 1.817e-03 | -6.31 | MODULE_438 | MSigDB lists | MODULE_438 | 67 | 15 | 17377 | 1707 |
TUBB4A,SH3GL2,MAP2,TACC2,KIF5A,LAMB1,HIP1,KIF5C,SNAP25,SEPT5,DYNC1I1,DSP,MID1,OCLN,SNPH |
| 1.817e-03 | -6.31 | KEGG_ADHERENS_JUNCTION | MSigDB lists | KEGG_ADHERENS_JUNCTION | 67 | 15 | 17377 | 1707 |
SMAD3,WASF3,FER,TCF7L1,SORBS1,PTPRJ,IGF1R,PTPN6,TJP1,MET,RAC3,CTNNA2,FGFR1,BAIAP2,SNAI2 |
| 1.821e-03 | -6.31 | negative regulation of phosphate metabolic process | biological process | GO:0045936 | 612 | 81 | 17256 | 1658 |
PHACTR3,PRKN,PPP4R4,DUSP8,DNAJC3,NPM1,NDRG2,CEBPA,NTRK3,PIBF1,PPM1E,PPP1R26,ZFYVE28,CNKSR3,DACT1,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,SPOCD1,PTPN6,LRRK2,PREX1,DEPTOR,ATF3,PRKAR2B,SYNJ2BP,SNCA,WARS,CAMK2N1,IRS2,ENPP1,PTPRJ,NCKAP1L,GBP1,WWTR1,DUSP19,HGF,GRB10,INPP5F,SPRY4,PPARGC1A,ARFGEF3,LATS2,MYO1D,FARP1,UBASH3B,IPO5,PKN1,DDIT4,MECOM,IGF1R,FLRT3,MYC,PRKCD,C1QL4,LRP6,ERRFI1,SMAD6,SPRY2,BOD1,DUSP1,HMGCR,GPR176,MSTN,DUSP9,PHACTR2,RACK1,DKK1,PTPRC,TRIB3,MYADM,PMEPA1,DLG2,LRRK1,BMP4,TESC,SMYD3,PKIA,SFN |
| 1.825e-03 | -6.31 | regulation of Ras protein signal transduction | biological process | GO:0046578 | 243 | 38 | 17256 | 1658 |
FARP1,RASAL2,ARHGEF11,GPR65,EPS8,OPHN1,PSD3,TIAM2,ARHGAP44,ARHGEF10L,RALGPS2,MCF2L,BCL6,DAB2IP,MET,SPRY2,PDGFRB,RASGRP1,VAV3,ARHGEF28,ARAP2,MCF2L2,CYTH3,ASAP3,SPATA13,PREX1,OBSCN,RASA3,AGAP2,ARHGEF26,RIPOR2,CSF1,RASGRF2,PLEKHG1,SPRY4,NRP1,IQSEC2,ARFGEF3 |
| 1.825e-03 | -6.31 | protein tyrosine phosphatase activity | molecular function | GO:0004725 | 102 | 20 | 17224 | 1680 |
SSH3,DUSP8,PTPRU,PTPRD,PTPN6,PTPN13,UBASH3B,PTPN21,DNAJC6,DUSP9,EYA4,PTPRC,PTPRJ,CDC14B,PALD1,DUSP19,PTPRS,PTPRN2,PTPRE,DUSP1 |
| 1.828e-03 | -6.30 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN | 183 | 31 | 17377 | 1707 |
ARHGEF11,RECK,COL4A4,PTPN13,HOMER2,CYP4V2,SELL,KIF5C,ADAMTS6,STAT5B,SLC12A6,SAV1,SFXN3,PEAK1,PFN2,ATP10D,CAMK2N1,ID3,TCF7L1,IGF1R,ZNF354A,PELI2,RBPMS2,ZNF521,COL19A1,LAPTM4B,NAP1L3,KLF9,CERS4,IGSF3,RRAGD |
| 1.828e-03 | -6.30 | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | 183 | 31 | 17377 | 1707 |
ARAP2,MXI1,TES,YPEL2,TNFSF13B,LITAF,NRN1,SCD,FAM117B,ADAMTS6,SFXN3,BATF3,MAPKAPK2,ENTPD1,IKZF3,RALGPS2,AKT3,CLDN12,ALDOC,FAM107B,RGS10,CCDC122,INPP5F,ST8SIA1,PCK2,TNFSF4,AGL,MLLT3,RASGRP1,RRAGD,GAB2 |
| 1.828e-03 | -6.30 | HAMAI_APOPTOSIS_VIA_TRAIL_DN | MSigDB lists | HAMAI_APOPTOSIS_VIA_TRAIL_DN | 183 | 31 | 17377 | 1707 |
TRPM4,VAV3,TRIM16,CACNA1E,PRDM13,BEGAIN,PACSIN3,LHPP,ISYNA1,F12,SEZ6L2,PHLDA2,BATF3,PYCR1,TYMP,TERT,HEYL,ALDOC,KCNG1,MAGEA3,SRD5A3,MAOA,STEAP3,SERPINH1,MAGEA6,PCK2,SLC1A5,PLTP,HOXB9,CDH2,BARX1 |
| 1.828e-03 | -6.30 | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN | MSigDB lists | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN | 183 | 31 | 17377 | 1707 |
ARHGAP26,TFCP2L1,FER,ZNF395,RHOBTB1,MPP1,BLVRB,ARID5B,YPEL2,PREX1,SDC3,PLS1,SORBS3,TNS1,LACC1,PKN1,SNX9,TBC1D16,SPATA7,SNCA,RERE,QPRT,TRPS1,GBGT1,FCHO2,MYC,SH3PXD2B,TMEM37,GATM,CEBPD,CRYL1 |
| 1.828e-03 | -6.30 | GSE40685_NAIVE_CD4_TCELL_VS_TREG_DN | MSigDB lists | GSE40685_NAIVE_CD4_TCELL_VS_TREG_DN | 183 | 31 | 17377 | 1707 |
FAM171B,CCDC126,ANKRD13B,FLVCR2,KDM5B,LGR4,PTPN13,ATP8A1,CYTH3,UBAC2,CYP4V2,PHACTR2,ITPR2,MBNL2,SLC46A3,RAC3,MFSD9,GRHL1,ZNF697,FAM168A,TMEM86A,DLX2,AGL,TBC1D4,PTPRE,TESC,SMYD3,C8orf48,RBMS2,PARP9,LPP |
| 1.828e-03 | -6.30 | XU_GH1_AUTOCRINE_TARGETS_UP | MSigDB lists | XU_GH1_AUTOCRINE_TARGETS_UP | 222 | 36 | 17377 | 1707 |
ARHGAP26,UGT8,ID1,BLVRB,OPHN1,C1orf226,HECW2,HERC5,SPATS2L,FAM198B,SATB1,PHGDH,ABHD4,FAM110B,DOCK2,SLCO3A1,PGAP1,ZNF827,GALNT1,CPE,RIMS2,NECAB1,FAM84A,SOX21,ST6GALNAC3,ROR1,STEAP1,SPATA7,SNCA,ID3,XBP1,SLC7A5,ADRB1,HOXB9,NR3C2,SLC43A1 |
| 1.833e-03 | -6.30 | GO_TISSUE_MORPHOGENESIS | MSigDB lists | GO_TISSUE_MORPHOGENESIS | 521 | 72 | 17377 | 1707 |
ACVR1,LGR4,ST14,GATA3,PKP2,DDR1,SKI,TGFBR3,SETDB2,EOMES,ITGB3,RAP2A,MET,SLIT2,PRKACB,SNAI2,NKX2-1,FZD1,INTU,KLHL3,WLS,YAP1,WNT11,DSP,FGFR1,SMAD3,PTK7,ITGA2,SEMA3C,BMPR1A,TMEFF2,NRP1,TPM1,COBL,HEY1,MEF2C,EFNB2,CELSR1,BMPR2,OVOL2,CA2,MYC,FRAS1,FLRT3,TFAP2A,LRP6,ACTA2,TSPAN12,SPRY2,EPB41L5,PAK1,VEGFC,MICAL2,MSX1,KDM5B,DCHS1,PRICKLE1,RYR2,SDK1,ZFPM2,HEG1,DKK1,FAT4,CSF1,HEYL,HOXD13,BMP4,SHOX2,SEMA3A,SIX2,BTRC,FOXA1 |
| 1.836e-03 | -6.30 | intracellular vesicle | cellular component | GO:0097708 | 2281 | 255 | 18223 | 1724 |
DOC2A,EXPH5,CACNG3,PRSS12,SYT12,ATP8A1,DNAJC3,LDLR,VAMP8,MCOLN3,ITPR2,SNX9,DNER,SLC9A7,NCS1,PCDH7,TXNDC5,ADPRHL1,RND2,TM9SF2,SEC16B,ZFYVE28,HPS1,MARVELD2,RAP2A,ITGB3,RAB26,TMED9,PACSIN1,MYRIP,TLR4,CPE,PDGFRB,LAMP3,TNK2,CD55,SLC3A2,ABCC4,WLS,ANK2,TGFA,LRRK2,LRMP,COTL1,TRIM9,GSN,TMEM150B,GPRC5B,HPSE,NCKAP1L,ENTPD7,ATP7B,ALDOA,ADRB1,AHNAK2,SERPINI1,INPP5F,PIK3C2B,NRP1,APBA2,MAGI2,RRAGD,PCSK5,CHMP4C,SV2B,FN1,LGALS3,RHOBTB1,SEC24D,GABRB2,SCN8A,ATP6V1E2,APBA1,DYNC1I1,SPINK5,MLC1,SPIRE1,MCOLN2,EEF2,SLC30A4,ABCA5,BACE2,SREBF1,LRP6,GRIP1,LMAN2,MPDZ,CADPS2,SLCO4C1,DENND1C,MOXD1,AGL,STXBP1,CKAP4,GPR161,SNX7,NOS3,FGFR4,BDNF,QSOX1,RHOQ,PNP,SLC27A2,FASN,PACSIN3,RYR2,HIP1,CALCRL,NPC2,SNAP25,RABAC1,ARRDC4,STEAP1,TMEM74,BAIAP2,TBC1D2,VPS37D,SH3GL2,FCHO2,PMEPA1,SH3BP4,RAB31,PTPRN2,LAPTM4B,PLD1,FNBP1L,MME,SFN,PLA2G4A,EPHA3,DMXL2,FRMPD3,PRKN,DNM3,AMOTL1,PCSK1N,SCAMP1,IL15,RHOD,RNF144A,MYO1B,MSR1,RGS20,ADD2,CANX,KIF21B,DOCK2,ZFYVE9,CD53,CCDC120,GPR15,TLR3,ERG28,UNC13B,ALDOC,STARD4,DAB2IP,STEAP3,PROS1,RAB27B,SYNGR3,CLVS2,SNX10,GCA,ANTXR2,EVL,GARS,TMEM67,TUBA1A,FZD4,PTPN6,PANK1,VIM,RARRES2,RAB38,DSP,TBC1D16,FRK,FGFR1,GABARAPL1,SNCA,ARHGAP21,PTPRJ,PAM,PTPRS,HGF,ATG5,SEPT5,CTTNBP2,STON2,ARFGEF3,TNIK,MYO1D,ANKRD13B,ANKRD13D,LPAR2,PRSS16,TSPAN15,GRB14,GLIPR1L1,RUSC2,BACE1,ATP9A,GABRG2,SELL,GAS6,PKN1,EPHB1,NDFIP2,SELENOP,ARHGAP44,RAB11FIP5,KCNJ4,RGS17,TECPR1,PRKCD,EHD3,KIAA0319,SGK3,MARCH3,TRIM3,MORN2,FIG4,MYO6,ESD,SYK,FES,VEGFC,SLC40A1,RAB3B,RAB6B,RAPGEF2,SYBU,LITAF,PHACTR2,ARHGAP32,ATP11A,FNDC3A,TLR6,LRAT,DKK1,PTPRC,FGR,ICA1,RND3,PRCP,CTSV,SLC1A5,TBC1D4,KIF1B,DDIT3,OCLN,ABCG1,TPT1,STOM |
| 1.836e-03 | -6.30 | SAM | smart domains | SM00454 | 84 | 19 | 9493 | 1056 |
EPHA3,ARAP2,INPPL1,SHANK2,PPFIBP2,PPFIA4,LCP2,EPHB1,PPP1R9A,L3MBTL4,PPFIBP1,PPFIA2,CNKSR3,KAZN,SAMD11,SFMBT1,EPHB6,MAP3K20,PHC1 |
| 1.842e-03 | -6.30 | WINTER_HYPOXIA_METAGENE | MSigDB lists | WINTER_HYPOXIA_METAGENE | 230 | 37 | 17377 | 1707 |
MXI1,FN1,BIK,COL4A5,F3,DDIT4,BACE2,SLC16A2,ALDOC,STC2,BNIP3,ERRFI1,MET,ENO1,IGFBP3,NOS3,PFKFB4,VEGFC,QSOX1,GAPDH,SLC3A2,PNP,NR4A1,TGFA,BNIP3L,VIM,HERPUD1,BATF3,INSIG1,PLOD2,P4HA2,ALDOA,HK2,P4HA1,HGF,HK1,DDIT3 |
| 1.850e-03 | -6.29 | connective tissue development | biological process | GO:0061448 | 195 | 32 | 17256 | 1658 |
CREB3L2,ZNF516,RUNX2,BMPR2,CHSY1,BMP6,COL27A1,ACTA2,LRP6,SH3PXD2B,SERPINH1,PDGFRB,MSX1,SMAD9,ARID5B,SATB2,FGFR1,GPLD1,DYRK1B,CSF1,XBP1,BMP1,SELENOM,DLX2,BMP4,BMPR1A,SPART,PPARGC1A,SHOX2,SIX2,FOXA1,MEF2C |
| 1.850e-03 | -6.29 | V$STAT5A_03 | MSigDB lists | V$STAT5A_03 | 238 | 38 | 17377 | 1707 |
PHACTR3,FN1,FGF13,KLHL13,UGDH,CADM2,CREB5,SATB1,DACH2,PPP2R3A,NEO1,TRPS1,FLRT3,BCL6,MYO3B,MARCKS,MYT1,ZNF385A,TUBA1A,KLHL3,SLITRK5,SLC25A28,PLEKHA1,KCND3,BCL11A,GPR150,ID3,FGR,IKZF3,PTK7,GNB4,PELI2,PLXDC2,ITGA2,SVIL,INPP5F,ZBTB20,FOXA1 |
| 1.854e-03 | -6.29 | GO_DIVALENT_INORGANIC_CATION_TRANSPORT | MSigDB lists | GO_DIVALENT_INORGANIC_CATION_TRANSPORT | 254 | 40 | 17377 | 1707 |
CACNG3,MCOLN3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,SLC30A4,BHLHA15,CACNB2,CNNM2,TRPC1,TMEM37,NIPAL2,ATP2B1,TRPM4,SLC40A1,GPM6A,SLC3A2,CSN2,CACNA1E,SLC39A8,ANK2,JPH1,RYR2,RASA3,CALCRL,ASPH,PTPRC,SLC39A14,CACHD1,PRKCB,BBC3,TRPC3,CACNA2D1,ATP2B4,DDIT3,DENND5B,TPT1 |
| 1.860e-03 | -6.29 | GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE | MSigDB lists | GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE | 319 | 48 | 17377 | 1707 |
SEMA6B,FN1,BMPR2,FGF13,EPS8,PLXNA2,ADD2,NTRK3,PFN2,SEMA6A,PPP1R9A,SPIRE1,FHOD3,SCIN,NKX6-1,RND2,SEMA4F,PRKCD,CTTN,IQGAP3,PRR16,SLIT2,NEB,SEMA6C,SSH3,BDNF,VAV3,FER,DISC1,EVL,RAB3B,DCC,DSTN,DEPTOR,PREX1,PLS1,BAIAP2,MAP1B,BCL11A,GSN,PLEKHH2,MYADM,NCKAP1L,WIPF3,SEMA3C,TMOD2,NRP1,SEMA3A |
| 1.872e-03 | -6.28 | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 191 | 32 | 17377 | 1707 |
MPZL3,SERINC5,USP2,SORBS1,ACSL1,RUNX2,IL15,PTPN6,FAM84A,HECW2,IL13RA1,CHAC1,TLR6,MCU,CD53,F3,MTUS1,GALNT3,ENTPD1,NRG3,SOAT2,CNTN4,IGF1R,SLC7A11,PIK3AP1,PPFIA2,CCDC146,BCL6,BMPR1A,GFI1,SPRY2,CKAP4 |
| 1.887e-03 | -6.27 | GTAAGAT,MIR-200A | MSigDB lists | GTAAGAT,MIR-200A | 48 | 12 | 17377 | 1707 |
SLC39A14,FGF13,NR4A1,FLRT3,GAN,NFIA,KCNS3,SGK1,KLF9,IPCEF1,NOVA1,FZD1 |
| 1.899e-03 | -6.27 | ribonucleoside diphosphate metabolic process | biological process | GO:0009185 | 62 | 14 | 17256 | 1658 |
GAPDH,ENO2,PFKFB2,MPP1,ALDOC,ALDOA,MPP2,OGDHL,HK2,PGM2L1,DLG2,HK1,ENO1,MAGI3 |
| 1.900e-03 | -6.27 | chr10p12 | MSigDB lists | chr10p12 | 36 | 10 | 17377 | 1707 |
ARMC4,OTUD1,ARHGAP21,PRTFDC1,MPP7,CACNB2,PLXDC2,KIAA1217,NRP1,MKX |
| 1.900e-03 | -6.27 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | MSigDB lists | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | 36 | 10 | 17377 | 1707 |
GSN,DSG2,PRKCD,PRKCQ,TJP1,VIM,SATB1,DSP,STK24,OCLN |
| 1.905e-03 | -6.26 | LANDIS_ERBB2_BREAST_TUMORS_324_UP | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_324_UP | 138 | 25 | 17377 | 1707 |
MOB1B,INPPL1,FLVCR2,NR4A1,TGFA,HOMER2,FHDC1,LITAF,WWC1,ENAH,CTBP2,ITPR2,TPD52L1,F3,GALNT3,EPCAM,PTK7,ALDOC,DSG2,XBP1,TUFT1,ERRFI1,ETV1,PERP,B4GALT6 |
| 1.906e-03 | -6.26 | negative regulation of phosphorus metabolic process | biological process | GO:0010563 | 613 | 81 | 17256 | 1658 |
PHACTR3,PRKN,PPP4R4,DUSP8,DNAJC3,NPM1,NDRG2,CEBPA,NTRK3,PIBF1,PPM1E,PPP1R26,ZFYVE28,CNKSR3,DACT1,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,SPOCD1,PTPN6,LRRK2,PREX1,DEPTOR,ATF3,PRKAR2B,SYNJ2BP,SNCA,WARS,CAMK2N1,IRS2,ENPP1,PTPRJ,NCKAP1L,GBP1,WWTR1,DUSP19,HGF,GRB10,INPP5F,SPRY4,PPARGC1A,ARFGEF3,LATS2,MYO1D,FARP1,UBASH3B,IPO5,PKN1,DDIT4,MECOM,IGF1R,FLRT3,MYC,PRKCD,C1QL4,LRP6,ERRFI1,SMAD6,SPRY2,BOD1,DUSP1,HMGCR,GPR176,MSTN,DUSP9,PHACTR2,RACK1,DKK1,PTPRC,TRIB3,MYADM,PMEPA1,DLG2,LRRK1,BMP4,TESC,SMYD3,PKIA,SFN |
| 1.906e-03 | -6.26 | LIU_VMYB_TARGETS_UP | MSigDB lists | LIU_VMYB_TARGETS_UP | 116 | 22 | 17377 | 1707 |
ARHGAP26,ARAP2,RHOQ,CRIM1,BNIP3L,PRKAR2B,SATB2,OVOL2,CA8,SLCO3A1,ISG20,MAPKAPK2,PPM1E,RPS6KA2,TACC2,LHX6,KCNS3,MARCH3,GRB10,PCOLCE2,HSPA2,SNX7 |
| 1.906e-03 | -6.26 | CRX_NRL_DN.V1_DN | MSigDB lists | CRX_NRL_DN.V1_DN | 116 | 22 | 17377 | 1707 |
QSOX1,INPPL1,PNP,GRIK2,NR4A1,HEBP1,PTPN13,ELOVL7,WWC1,KIF5C,PRDM1,ASPH,JAM3,CRYBG3,IL17D,KAZN,RASGRF2,PAM,RTKN2,RAB27B,SMPDL3A,HRASLS |
| 1.912e-03 | -6.26 | GSE37336_LY6C_POS_VS_NEG_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE37336_LY6C_POS_VS_NEG_NAIVE_CD4_TCELL_UP | 153 | 27 | 17377 | 1707 |
ENO2,C3orf52,TMEM200C,ATF3,PALLD,ARRDC4,EPHB1,BEX2,STK24,DCBLD2,IRS2,RAB11FIP5,RGS17,TRIB3,HLF,LRRN1,FAT1,MAGEA3,SERPINI1,MAGEA6,SHOX2,KLHL29,TNFRSF11A,KIAA1549,IL1RAP,ATP2B1,LAMP3 |
| 1.912e-03 | -6.26 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | 153 | 27 | 17377 | 1707 |
MXI1,PDK1,ESRRG,RAPGEF4,DHCR24,ADCY1,AK4,NHP2,TBC1D30,MTUS1,BCL11A,RTN1,ICA1,RPS6KA2,INSIG1,ALDOC,MYC,MAP2K6,CHRDL1,HK2,MAOA,MARCKS,SMAD6,ETV1,SPRY2,MLLT3,IGSF3 |
| 1.923e-03 | -6.25 | GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 462 | 65 | 17377 | 1707 |
NEK10,AVPI1,ACSL1,FGF13,NTRK3,LCP2,PIBF1,SNX9,PPP1R9A,TLR3,ITGB3,DAB2IP,MARCKS,TLR4,HSPA2,PRKACB,RASGRP1,PDGFRB,FZD4,PFKFB2,TGFA,LRRK2,ADCY1,WNT11,PRKAR2B,ACVR2B,CD40,FGFR1,SNCA,NRG3,GPRC5B,NCKAP1L,ERN1,DUSP19,TNFSF15,DIRAS1,HGF,MAPK10,TNIK,FZD8,GAS6,PKN1,TPD52L1,GHR,PRKCD,ADCY6,AFAP1L2,IQGAP3,SYK,SPRY2,TNFRSF11A,PAK1,VAV3,RAPGEF2,VLDLR,STRADB,DUSP9,TLR6,PTPRC,MAPKAPK2,FGR,MAP2K6,CSF1,BMP4,ATP2B4 |
| 1.930e-03 | -6.25 | AMIT_EGF_RESPONSE_40_HELA | MSigDB lists | AMIT_EGF_RESPONSE_40_HELA | 42 | 11 | 17377 | 1707 |
CEBPB,RNF141,ID1,NR4A1,RPS11,CCNA1,LDLR,SGK1,ATF3,MBNL2,DUSP1 |
| 1.930e-03 | -6.25 | GO_DENDRITE_MORPHOGENESIS | MSigDB lists | GO_DENDRITE_MORPHOGENESIS | 42 | 11 | 17377 | 1707 |
FARP1,MAP2,RBFOX2,LRP4,VLDLR,SLITRK5,EPHB1,SEMA3A,CTNND2,CTNNA2,RERE |
| 1.932e-03 | -6.25 | Tyr_Pase_cat | interpro domains | IPR003595 | 61 | 14 | 18492 | 1811 |
PTPRC,PTPRJ,PTPRU,CDC14B,PTPRD,PTPN6,PTPN13,PTPN21,PALD1,PTPRN2,PTPRS,TNS1,PTPRE,DUSP1 |
| 1.939e-03 | -6.25 | V$SRY_01 | MSigDB lists | V$SRY_01 | 207 | 34 | 17377 | 1707 |
NBL1,MXI1,SORBS1,TCP11L2,PLXNA2,CYP26A1,NOS1AP,HECTD2,DDIT4,ZNF362,ABLIM1,RALGPS2,FAM107B,LRP6,ST8SIA1,NCAM1,MORN4,GFRA1,CKAP4,GAB2,SESN2,ESRRG,CACNA1E,DCHS1,NFIA,MSRB3,CTTNBP2NL,MAGI3,GABARAPL1,ENTPD1,PLXDC2,C1orf21,B3GALT2,DLG2 |
| 1.944e-03 | -6.24 | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | 176 | 30 | 17377 | 1707 |
PAK1,ATL1,NMNAT3,CYP2J2,SPATA6,ITGA6,PPFIBP2,TCEA3,PLXNA2,NDRG2,CBY1,CCNG1,ARRDC4,ZNF711,LMLN,IGF1R,BACH2,FMO4,MYC,OSBPL5,SREBF1,SCRN1,NBEA,CYP2U1,ALPK1,RNF157,NR3C2,CHRM3,SLC16A10,ZNF391 |
| 1.944e-03 | -6.24 | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP | MSigDB lists | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP | 176 | 30 | 17377 | 1707 |
LONRF1,QSOX1,FER,TTC39B,COL4A3,IL15,TBC1D8B,CHCHD7,RNF144A,HEBP1,NFIA,PSD3,PRKAR2B,SLC25A28,SLCO3A1,NAALADL2,ATP10D,ICA1,HLF,CA2,ZNF438,PDZD8,SH3GL2,MARVELD2,ALDH1L1,HGF,GRB10,CERS4,TLR4,MLLT3 |
| 1.947e-03 | -6.24 | regulation of platelet activation | biological process | GO:0010543 | 31 | 9 | 17256 | 1658 |
UBASH3B,PRKCD,PRKG1,PRKCQ,ABAT,PRKCA,TLR4,SYK,NOS3 |
| 1.947e-03 | -6.24 | cellular response to dexamethasone stimulus | biological process | GO:0071549 | 31 | 9 | 17256 | 1658 |
ASS1,ABCC2,FBXO32,PCK2,ERRFI1,MSTN,EIF4EBP1,SMYD3,DDIT4 |
| 1.947e-03 | -6.24 | face morphogenesis | biological process | GO:0060325 | 31 | 9 | 17256 | 1658 |
MSX1,ARID5B,LRP6,PLEKHA1,PAX9,ASPH,CRISPLD1,SKI,DKK1 |
| 1.952e-03 | -6.24 | organic acid metabolic process | biological process | GO:0006082 | 986 | 122 | 17256 | 1658 |
PLA2G4A,NMNAT3,ACSL1,ELOVL4,AASS,IL15,XYLT1,UGDH,ASS1,STAT5B,SLC7A2,ABAT,BCAN,LPIN3,AARS,CYP26A1,QPRT,ASNS,AADAT,KMO,ERO1B,FAAH2,ALDOC,ALDH1L1,MDH1B,ENO1,GATM,CTH,GLDC,CYP1B1,VNN2,SESN2,ATF4,GAPDH,GARS,UROS,CEMIP2,PFKFB2,ALDH1L2,ACO1,HACD1,PRKAR2B,GSTO1,ABCC2,SNCA,PYCR1,WARS,ENPP1,TDO2,PEMT,ALDOA,BDH2,TNFRSF1A,PAM,HPGD,P4HA1,DSEL,HGF,CYP2U1,PPARGC1A,SPOCK3,PSPH,CRYL1,PRKAA2,UST,CARS,GPT2,SERINC5,ALOX5AP,EHHADH,ENO2,GCAT,CYP2J2,ST6GAL1,OLAH,ELOVL7,RIMKLA,CYP4V2,CBS,SCD,CHSY1,SLC1A3,PHGDH,ADSSL1,MSMO1,GHR,PHYKPL,SLC16A9,PCK2,SYK,NOS3,B4GALT6,CHSY3,FADS1,ATP5IF1,PODXL2,GSTM2,HYKK,PNP,SLC27A2,MGST3,ELOVL3,FASN,OGDHL,MARS,AIG1,AMDHD1,GLCE,MAPKAPK2,DAGLA,DDAH1,RIMKLB,GSTO2,PLOD2,XBP1,SLC7A5,HK2,PGM2L1,HK1,PTGES,OSBPL6,ACSM3 |
| 1.953e-03 | -6.24 | GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 109 | 21 | 17377 | 1707 |
GSTM2,PTPN6,UBASH3B,ANK2,JPH1,RYR2,GSTO1,ATP1B1,CACNB4,ASPH,NOS1AP,SNCA,CXCL10,CACNB2,TRPC1,TSPAN13,BMP4,PDE4D,ATG5,HSPA2,CACNA2D1 |
| 1.962e-03 | -6.23 | F_BAR | interpro domains | IPR031160 | 25 | 8 | 18492 | 1811 |
FER,PACSIN1,FNBP1L,FCHO2,PSTPIP2,FES,PACSIN3,SRGAP1 |
| 1.972e-03 | -6.23 | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | 81 | 17 | 17377 | 1707 |
BDNF,ARAP2,VLDLR,HEG1,DKK1,CTIF,RANBP2,TGFBR3,IGF1R,FAM168A,SFMBT1,BMPR1A,FAM155A,CDH2,SLIT2,BTRC,DOCK9 |
| 1.972e-03 | -6.23 | ATGTCAC,MIR-489 | MSigDB lists | ATGTCAC,MIR-489 | 81 | 17 | 17377 | 1707 |
BCL11B,PCDH10,IPO5,NTRK3,NOVA1,RERE,BCL11A,SMAD3,NSD1,BACH2,FBN1,STC2,OPN3,SGK1,PDE4D,PURG,SCN3A |
| 1.979e-03 | -6.23 | V$SMAD3_Q6 | MSigDB lists | V$SMAD3_Q6 | 223 | 36 | 17377 | 1707 |
ACVR1,MRC2,SLC6A9,BMPR2,ATP6V1E2,RASL11B,NTRK3,HMCN1,EYA4,ATXN7L1,KCTD15,FRY,CACNB2,LHX6,SMTN,SERINC2,PDE4D,SMAD6,MYT1,NOS3,NKX2-1,FZD1,MN1,NDUFA4L2,ESRRG,AGPAT4,PTPN6,SAV1,EBF1,PLEKHH2,MAP2,C1orf21,B3GALT2,NXPH4,GRIN2D,DOCK9 |
| 1.980e-03 | -6.22 | mitogen-activated protein kinase kinase binding | molecular function | GO:0031434 | 68 | 15 | 17224 | 1680 |
EPHA3,TYRO3,FGFR4,TRIB3,IGF1R,MAP3K21,NTRK3,DAB2IP,ROR1,EPHB6,MET,EPHB1,DDR1,FGFR1,PDGFRB |
| 1.983e-03 | -6.22 | cerebral cortex cell migration | biological process | GO:0021795 | 43 | 11 | 17256 | 1658 |
FGF13,LHX6,LAMB1,EFHC1,DAB2IP,NRP1,SEMA3A,FOXG1,SLIT2,POU3F3,NKX2-1 |
| 1.984e-03 | -6.22 | oxoacid metabolic process | biological process | GO:0043436 | 968 | 120 | 17256 | 1658 |
PLA2G4A,NMNAT3,ACSL1,ELOVL4,AASS,IL15,XYLT1,UGDH,ASS1,STAT5B,SLC7A2,ABAT,BCAN,LPIN3,AARS,CYP26A1,QPRT,ASNS,AADAT,KMO,ERO1B,FAAH2,ALDOC,ALDH1L1,MDH1B,ENO1,GATM,CTH,GLDC,CYP1B1,VNN2,SESN2,ATF4,GAPDH,GARS,UROS,CEMIP2,PFKFB2,ALDH1L2,ACO1,HACD1,PRKAR2B,GSTO1,ABCC2,SNCA,PYCR1,WARS,ENPP1,TDO2,PEMT,ALDOA,BDH2,TNFRSF1A,PAM,HPGD,P4HA1,DSEL,HGF,CYP2U1,PPARGC1A,SPOCK3,PSPH,CRYL1,PRKAA2,UST,CARS,GPT2,SERINC5,ALOX5AP,EHHADH,ENO2,GCAT,CYP2J2,ST6GAL1,OLAH,ELOVL7,RIMKLA,CYP4V2,CBS,SCD,CHSY1,SLC1A3,PHGDH,ADSSL1,MSMO1,GHR,PHYKPL,PCK2,SYK,NOS3,B4GALT6,CHSY3,FADS1,ATP5IF1,PODXL2,GSTM2,HYKK,SLC27A2,MGST3,ELOVL3,FASN,OGDHL,MARS,AIG1,AMDHD1,GLCE,MAPKAPK2,DAGLA,DDAH1,RIMKLB,GSTO2,PLOD2,XBP1,SLC7A5,HK2,PGM2L1,HK1,PTGES,OSBPL6,ACSM3 |
| 1.985e-03 | -6.22 | EGF_CA | prosite domains | PS01187 | 95 | 20 | 12060 | 1278 |
LRP4,VLDLR,LDLR,C1R,GAS6,DNER,HMCN1,HEG1,EFEMP1,NELL2,FAT4,FBN1,FAT1,CCBE1,THBS4,BMP1,EGFL7,PROS1,SLIT2,TLL2 |
| 1.986e-03 | -6.22 | heart morphogenesis | biological process | GO:0003007 | 236 | 37 | 17256 | 1658 |
ACVR1,BMPR2,GATA3,PKP2,OVOL2,ADGRG6,TGFBR3,SETDB2,SMAD6,CPE,SNAI2,FZD1,MICAL2,MSX1,DCHS1,FHL2,NSD2,YAP1,SMARCD3,RYR2,WNT11,ZFPM2,SAV1,DSP,HEG1,SMAD3,FAT4,HEYL,MYOM2,SEMA3C,BMP4,BMPR1A,TPM1,NRP1,SHOX2,MEF2C,HEY1 |
| 1.987e-03 | -6.22 | GO_CARDIAC_VENTRICLE_MORPHOGENESIS | MSigDB lists | GO_CARDIAC_VENTRICLE_MORPHOGENESIS | 61 | 14 | 17377 | 1707 |
TGFBR3,HEYL,GATA3,PKP2,SMARCD3,RYR2,SEMA3C,ZFPM2,TPM1,CPE,DSP,HEY1,MEF2C,HEG1 |
| 1.987e-03 | -6.22 | GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 | MSigDB lists | GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 | 61 | 14 | 17377 | 1707 |
C2orf88,MYO1D,ARHGAP21,CARD6,AMOTL1,HMGCS1,SCAMP1,PLEKHA5,SGK1,KIAA0408,GPSM2,SMAD6,ABHD6,C9orf116 |
| 1.987e-03 | -6.22 | ATGTAGC,MIR-221,MIR-222 | MSigDB lists | ATGTAGC,MIR-221,MIR-222 | 131 | 24 | 17377 | 1707 |
PAK1,EIF4E3,MYO10,SHANK2,SYBU,FERMT2,IGF2BP2,C3orf70,ZFPM2,FNDC3A,FAM13A,KHDRBS2,NOVA1,HECTD2,TRPS1,NAP1L5,INSIG1,TOX,CLVS2,PPARGC1A,MAPK10,VGLL4,LIFR,ZNF385A |
| 1.987e-03 | -6.22 | GO_ODONTOGENESIS | MSigDB lists | GO_ODONTOGENESIS | 102 | 20 | 17377 | 1707 |
BCL11B,ENAM,SCN5A,MSX1,RUNX2,ITGA6,LRP4,ACVR2B,ID3,CA2,CSF1,LAMB1,PAM,LRP6,TUFT1,BMPR1A,BMP4,DLX2,PAX9,PERP |
| 1.989e-03 | -6.22 | cardiac septum morphogenesis | biological process | GO:0060411 | 69 | 15 | 17256 | 1658 |
ACVR1,TGFBR3,BMPR2,HEYL,NSD2,SEMA3C,WNT11,BMPR1A,BMP4,ZFPM2,SAV1,NRP1,SMAD6,FZD1,HEY1 |
| 1.993e-03 | -6.22 | GO_PROTEIN_PHOSPHORYLATION | MSigDB lists | GO_PROTEIN_PHOSPHORYLATION | 920 | 117 | 17377 | 1707 |
EPHA3,BTC,NEK10,ACVR1,RASAL2,FGF13,IL15,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,PIBF1,STK24,MOK,SPEG,TGFBR3,TLR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,DAB2IP,EPHB6,MET,TLR4,RASGRP1,PRKACB,PDGFRB,IGFBP3,TNK2,FER,MYLK3,MARK1,PDK1,SMAD9,ACVR1C,ADM2,KCNH5,PTPN6,LRRK2,FGF12,PRKCQ,WNT11,ACVR2B,FGF17,ROR1,SGK2,FRK,FGFR1,IRS2,DYRK1B,PRKCB,PTK7,PLK2,RASGRF2,ABI3,ERN1,MAPK13,OXTR,BMPR1A,MAPK10,MEF2C,MAST1,TYRO3,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,SLK,GAS6,PKN1,EPHB1,TNFRSF19,DOK5,EFEMP1,IGF1R,ADCK1,MYC,PRKCD,GHR,PRKG1,SGK3,SGK1,PRKG2,ALPK1,IQGAP3,NCAM1,MAST4,SYK,GFRA1,FES,FGFR4,PAK1,IL17RD,RAPGEF2,NUAK2,DUSP9,OBSCN,RASA3,STRADB,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,MAP2K6,AKT3,NEK11,GRIN2D,LRRK1,BMP4,BTRC |
| 1.994e-03 | -6.22 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_UP | 161 | 28 | 17377 | 1707 |
ITGB7,FN1,XYLT1,HOMER2,FHL2,NDRG2,PRKAR2B,ATP11A,PALLD,HOPX,GNAI1,NEGR1,MCOLN2,MPP7,CCNA1,OPN3,ADRB1,CDH17,HPGD,TOX,GEM,CMPK2,RAB27B,SLC45A3,SMYD3,SMPDL3A,DENND5B,LAMP3 |
| 1.994e-03 | -6.22 | KIM_WT1_TARGETS_8HR_UP | MSigDB lists | KIM_WT1_TARGETS_8HR_UP | 161 | 28 | 17377 | 1707 |
NBL1,RHOQ,ENO2,BMPR2,ATP9A,TNS1,ABAT,DOK5,PHLDA2,FGFR1,BAIAP2,PCDH7,TBC1D2,SLC7A1,CDR2L,PDE10A,CSF1,PRKCD,WWTR1,GRB10,DLX2,GEM,SERPINH1,IL1RAP,SFN,ATP2B1,SNAI2,B4GALT6 |
| 1.994e-03 | -6.22 | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_UP | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_UP | 161 | 28 | 17377 | 1707 |
MPZL3,CDH26,BMPR2,CMTM8,LACC1,PRKCA,TNFRSF19,DOCK2,NOS1AP,EPDR1,RERE,ZNF362,SH3GL2,TM9SF2,FCHO2,FUT9,GPR160,COL25A1,GAS2L3,GHR,PGM2L1,SGK1,FMNL2,SYK,SMPDL3A,ALG10B,TBC1D8,STOM |
| 1.996e-03 | -6.22 | GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 184 | 31 | 17377 | 1707 |
AVPI1,ENO2,LITAF,RASA3,MARS,STAT5B,ATP11A,HERC6,ZNF219,SATB1,CA8,DDR1,HECTD2,SKI,CAMK2N1,TEX15,ZNF362,RALGPS2,PMEPA1,MCF2L,FAM114A2,ADCY6,PTPRS,MARCKS,ST8SIA1,FAM84B,RNF157,TMEM120B,PURG,IGSF3,ABCG1 |
| 1.996e-03 | -6.22 | GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | MSigDB lists | GSE4748_CTRL_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | 184 | 31 | 17377 | 1707 |
BDNF,RIN2,RGS16,GNG12,ANTXR2,FARP1,TES,TMTC4,GTF2IRD1,SLC25A28,GSTO1,NPC2,FNDC3A,PEAK1,BMP6,C1orf174,CD53,RASSF8,PLXDC2,MATN2,RAP2A,GHR,RAI14,SGK1,PCOLCE2,ERRFI1,ESD,ETV1,JAM2,IL1RAP,SLIT2 |
| 1.996e-03 | -6.22 | GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN | MSigDB lists | GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN | 184 | 31 | 17377 | 1707 |
CCDC126,MYCBP2,CARD6,EVL,TCP11L2,PFKFB2,ATP8A1,SLC25A27,SELL,CALCRL,NPM1,ZDHHC14,CD7,SATB1,KBTBD11,SKI,ATXN7L1,ID3,SEMA4F,RASGRF2,REEP1,ABI3,RUNDC3B,ZBTB20,TSPAN13,DBP,SLFN5,TESC,RASGRP1,DDIT3,ABCG1 |
| 1.996e-03 | -6.22 | GO_PEPTIDYL_TYROSINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_TYROSINE_MODIFICATION | 184 | 31 | 17377 | 1707 |
EPHA3,FGFR4,TYRO3,TNK2,FER,BTC,DYRK3,IL15,PTPN6,NTRK3,STAT5B,FGF17,ROR1,EPHB1,FRK,DDR1,PIBF1,PEAK1,FGFR1,DYRK1B,EFEMP1,FGR,IGF1R,MAP2K6,PRKCD,GHR,ABI3,MET,SYK,PDGFRB,FES |
| 1.996e-03 | -6.22 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_DN | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_DN | 184 | 31 | 17377 | 1707 |
UST,FGF13,PRSS12,TBC1D1,DSTN,PTPN21,PREX1,ZNF605,COBLL1,PDE8A,PRDM1,CHSY1,USP30,CD7,IL18R1,HECTD2,SMPDL3B,PLEKHB1,TIAM2,TXNDC5,NAP1L5,EFEMP1,SFXN1,IKZF3,MYADM,CDC14B,C1orf21,ITGB3,DYNC2LI1,NCEH1,MYO6 |
| 1.996e-03 | -6.22 | GSE3982_BCELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_BCELL_VS_BASOPHIL_DN | 184 | 31 | 17377 | 1707 |
MRC2,ACVR1,ELOVL4,IL32,CRIM1,PSTPIP2,MPP1,SDC3,GSTO1,SLC12A6,PALLD,CA8,DENND3,CEBPB,SFXN1,SYCP2,FRY,RAB31,SEMA3C,GRB10,FAR2,TLR4,FNBP1L,MYRIP,CDH2,PTGES,LRP12,ATP2B4,RRAGD,DUSP1,TPT1 |
| 1.996e-03 | -6.22 | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN | 184 | 31 | 17377 | 1707 |
UST,CARS,MTG1,DMXL2,GNG12,PLSCR4,COL6A2,ALDH2,RECK,ZCCHC24,RAPGEF2,BACE1,MGAT4B,RAPGEF4,CBS,COL4A5,IGF2BP2,SCD,CHSY1,DOK5,NT5DC2,GAS1,HOMER3,BCHE,GATA2,KAZN,DSG2,FBXL2,MOXD1,SLIT2,LRP12 |
| 1.996e-03 | -6.22 | YAGI_AML_FAB_MARKERS | MSigDB lists | YAGI_AML_FAB_MARKERS | 184 | 31 | 17377 | 1707 |
FADS1,CFH,STAT4,ITGA6,ARID5B,DHCR24,ACO1,CDC42BPA,SFXN3,DOK5,SLC7A1,TYMP,HMGCS1,ADAMTS3,PLOD2,GATA2,ITGB3,SCRN1,SQLE,LAPTM4B,TRPC1,SERPINI1,NAP1L3,PROS1,SERPINH1,NCAM1,TPM1,RAB27B,RRAS2,MAST4,PKIA |
| 2.000e-03 | -6.21 | KIM_HYPOXIA | MSigDB lists | KIM_HYPOXIA | 25 | 8 | 17377 | 1707 |
BNIP3,ENO2,NKX3-2,ALDOC,ALDOA,F3,BNIP3L,IGFBP3 |
| 2.000e-03 | -6.21 | GO_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | 25 | 8 | 17377 | 1707 |
EGFL7,DLX2,CHAC1,OVOL2,GDPD5,GATA2,HEY1,BCL6 |
| 2.001e-03 | -6.21 | LIU_PROSTATE_CANCER_UP | MSigDB lists | LIU_PROSTATE_CANCER_UP | 88 | 18 | 17377 | 1707 |
EPCAM,TRPM4,PPM1E,FARP1,ABCC4,ST14,SH3RF1,MAP2K6,TMTC4,BEND4,TSPAN13,MYO6,TBC1D4,DNAH5,PPP1R9A,ARHGEF26,SLC43A1,PYCR1 |
| 2.003e-03 | -6.21 | WTGAAAT_UNKNOWN | MSigDB lists | WTGAAAT_UNKNOWN | 566 | 77 | 17377 | 1707 |
SORBS1,TCP11L2,CFH,FGF13,COBLL1,CADM2,DNER,IKZF5,NBEA,BEND4,MYT1,DZANK1,GPM6A,GARS,CSN2,GDPD1,ROR1,TMEM47,SMAD3,ENTPD1,ARHGAP21,EIF4EBP1,B3GALT2,ZBTB20,NRP1,HOXB9,SLC9B1,PURG,MID1,MEF2C,BCL11B,TYRO3,WDR17,FN1,RHOBTB1,OTOGL,PTPRD,REL,SCN8A,P2RY1,SLC1A3,PKN1,FOXG1,TNFRSF19,INPP1,ARHGAP44,NEDD4,MECOM,FOXP2,FRY,GATA2,STC2,ERRFI1,MN1,PCDH10,ENAM,USP2,PACSIN3,NUAK2,SLITRK5,UCHL3,ARRDC4,SPATA7,RERE,ZIC1,DKK1,PELI2,C1orf21,SH3BP4,PGM2L1,SQLE,SH3BGRL2,DLG2,PAX9,SEMA3A,SNPH,TLL2 |
| 2.003e-03 | -6.21 | SPTBN1 (spectrin beta, non-erythrocytic 1) | protein interactions | 6711 | 135 | 25 | 17029 | 1718 |
DBN1,PDLIM7,DISC1,TNIK,FN1,SMAD9,NOP53,ANK2,TES,PLEKHA5,UBASH3B,CEBPA,PYGO1,TNKS1BP1,PLCB1,SNCA,SMAD3,EPB41L3,SVIL,PJA1,PACSIN1,TPM1,STXBP1,CDH2,MEF2C |
| 2.007e-03 | -6.21 | buttock | COSMIC cancer mutations | buttock | 68 | 15 | 17385 | 1698 |
PTPRC,FER,PTPRJ,TERT,PTPRD,PTK7,PPFIBP1,PTPN13,PTPN21,PTPRS,PTPRN2,TNS1,EPHB1,MET,PTPRE |
| 2.009e-03 | -6.21 | Bbox_C | interpro domains | IPR003649 | 15 | 6 | 18492 | 1811 |
TRIM3,FSD1,TRIM9,MID2,TRIM2,MID1 |
| 2.012e-03 | -6.21 | GO_PEPTIDYL_SERINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_SERINE_MODIFICATION | 146 | 26 | 17377 | 1707 |
PRKAA2,LATS2,LRRK2,PRKCQ,GAS6,PKN1,PRKCA,SGK2,MAPKAPK2,GALNT3,GALNT1,RPS6KA2,PKN3,PRKCB,AKT3,PLK2,PRKCD,ERN1,SGK3,SGK1,PRKG2,MAPK13,MAST4,SYK,SPOCK3,MAST1 |
| 2.015e-03 | -6.21 | response to monoamine | biological process | GO:0071867 | 37 | 10 | 17256 | 1658 |
PRKN,ID1,ATF4,LRRK2,ADCY6,RYR2,PDE4D,PPARGC1A,ATP2B4,SNCA |
| 2.015e-03 | -6.21 | response to catecholamine | biological process | GO:0071869 | 37 | 10 | 17256 | 1658 |
PRKN,ID1,ATF4,LRRK2,ADCY6,RYR2,PDE4D,PPARGC1A,ATP2B4,SNCA |
| 2.018e-03 | -6.21 | peptidyl-serine modification | biological process | GO:0018209 | 204 | 33 | 17256 | 1658 |
PRKAA2,LATS2,GALNT12,GALNT6,CHUK,GALNT13,GAS6,PKN1,PRKCA,GALNT1,PRKCD,SGK3,SGK1,PRKG2,MAST4,GALNT18,SYK,MYLK3,LRRK2,PRKCQ,GALNT17,SGK2,GALNT14,GALNT3,MAPKAPK2,PKN3,PRKCB,AKT3,PLK2,ERN1,MAPK13,SPOCK3,MAST1 |
| 2.018e-03 | -6.21 | positive regulation of cytoskeleton organization | biological process | GO:0051495 | 204 | 33 | 17256 | 1658 |
TENM1,ID1,GPR65,ARL2,SORBS3,NTRK3,GPSM2,PFN2,RAC3,SPIRE1,SCIN,ARHGEF10L,PPM1E,SH3PXD2B,CTTN,MET,FES,PAK1,FER,MYLK3,PXN,EVL,SYNPO2,DSTN,WNT11,BAIAP2,SMAD3,GSN,RANBP2,NCKAP1L,WIPF3,NRP1,TPM1 |
| 2.025e-03 | -6.20 | skin-back-malignant_melanoma | COSMIC cancer mutations | skin-back-malignant_melanoma | 281 | 43 | 17385 | 1698 |
OR51B5,EXPH5,TNIK,PCDH18,PPP4R4,CACNG3,AASS,PTPRD,PLAG1,LSM11,PTPN21,EPHB1,ZNF219,COLEC10,TNFRSF19,PCLO,MAP1A,APLF,GHR,NAP1L3,MET,IQGAP3,PTPRE,DNAH5,CHRM3,FER,DCC,KCNH5,PTPN13,TNS1,KHDRBS2,EBF1,PTPRC,ZNF711,TMEM132B,PTPRJ,PLAGL1,ADAMTS3,PTK7,PTPRS,PTPRN2,SLFN5,AMPD1 |
| 2.031e-03 | -6.20 | AMPK signaling pathway | KEGG pathways | hsa04152 | 120 | 23 | 7161 | 730 |
CREB3L2,PFKFB4,PRKAA2,TBC1D1,PFKFB2,FASN,STRADB,SCD,CREB5,LEPR,PPP2R3A,IRS2,IGF1R,EEF2,AKT3,EIF4EBP1,CCNA1,SREBF1,CAB39L,PPP2R2B,PCK2,PPARGC1A,HMGCR |
| 2.031e-03 | -6.20 | AMPK signaling pathway | KEGG pathways | ko04152 | 120 | 23 | 7161 | 730 |
CREB3L2,PFKFB4,PRKAA2,TBC1D1,PFKFB2,FASN,STRADB,SCD,CREB5,LEPR,PPP2R3A,IRS2,IGF1R,EEF2,AKT3,EIF4EBP1,CCNA1,SREBF1,CAB39L,PPP2R2B,PCK2,PPARGC1A,HMGCR |
| 2.040e-03 | -6.19 | GSE18893_TCONV_VS_TREG_24H_CULTURE_DN | MSigDB lists | GSE18893_TCONV_VS_TREG_24H_CULTURE_DN | 192 | 32 | 17377 | 1707 |
PLA2G4A,BCL7A,SERINC5,VAV3,EIF4E3,BMPR2,PNRC1,FGF13,MPP1,ATP8A1,LPCAT2,RAPGEF4,LRMP,LRRK2,MCOLN3,SATB1,INPP1,TRPS1,TIFA,BACH2,CA2,SLC30A4,KMO,ITGB3,BCL6,MAP7,INPP5F,TANC2,CMPK2,RNF157,RAPGEF5,CSRP2 |
| 2.040e-03 | -6.19 | GO_POLYPEPTIDE_N_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_POLYPEPTIDE_N_ACETYLGALACTOSAMINYLTRANSFERASE_ACTIVITY | 15 | 6 | 17377 | 1707 |
GALNT3,GALNT13,GALNT1,GALNT14,GALNT6,GALNT12 |
| 2.040e-03 | -6.19 | GO_ENDOCARDIAL_CUSHION_FORMATION | MSigDB lists | GO_ENDOCARDIAL_CUSHION_FORMATION | 15 | 6 | 17377 | 1707 |
MSX1,BMPR1A,HEYL,DCHS1,SNAI2,HEY1 |
| 2.048e-03 | -6.19 | GO_NEGATIVE_REGULATION_OF_CELL_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_PROLIFERATION | 610 | 82 | 17377 | 1707 |
IL15,GATA3,LILRB1,PKP2,COL18A1,NDRG2,NPM1,CTBP2,CEBPA,DDR1,SCIN,SKI,SPEG,TGFBR3,RPS6KA2,PMAIP1,FABP6,BCL6,DAB2IP,SNAI2,CYP1B1,IGFBP3,INTU,SKAP2,COL4A3,PTPRU,ACVR1C,TES,PTPN6,WNT11,SYNJ2BP,SAV1,FRK,ASPH,SESN1,WARS,SMAD3,PTPRJ,PEMT,PPARGC1A,TPM1,MAGI2,MEF2C,BCL11B,EFNB2,INPPL1,MXI1,BMPR2,IGFBP6,CD276,DHCR24,OVOL2,PKN1,CHD5,GATA2,BCHE,MYC,C1QL4,TFAP2A,KLF9,SMAD6,SPRY2,NOS3,VEGFC,PAK1,MSX1,MSTN,RAPGEF2,PRDM1,CPEB1,GPLD1,CEBPB,NACC2,MCC,SH3BP4,CLMN,BMP4,NKX2-8,PTGES,TESC,B4GALT7,SFN |
| 2.050e-03 | -6.19 | cellular response to ketone | biological process | GO:1901655 | 83 | 17 | 17256 | 1658 |
PRKAA2,MSTN,ADCY1,ASS1,ABCC2,DDIT4,GNAI1,FBXO32,EIF4EBP1,ADCY6,KLF9,ERRFI1,PCK2,TNFSF4,SMYD3,LARP1,ATP2B1 |
| 2.050e-03 | -6.19 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-hairy_cell_leukaemia | 1469 | 176 | 17385 | 1698 |
MYCBP2,THOC5,UGT8,DNAJC3,MCOLN3,GATA3,NPM1,CEBPA,DNER,IKZF2,EYA4,KCNN2,EOMES,DNAH6,PPFIA2,FAAH2,SERINC2,MPPED2,COL19A1,ATRNL1,JAKMIP2,RCAN3,OR2W3,TSHR,KCNIP3,MARK1,DCC,NR6A1,ANK2,JPH1,LRRK2,DEPTOR,TTC22,TNS1,MFSD6,GPC6,ARHGEF26,DYRK1B,ENPP1,NCKAP1L,ITGBL1,NCAM2,ARHGAP28,CAB39L,MAGI2,ZNF395,SEC24D,FBXO4,OPHN1,MRPL22,LRRC49,ZNF215,ISYNA1,GPSM2,IL18R1,MTUS1,FRY,BCHE,ZNF440,GATA2,FRAS1,CACNB2,ZIC5,LRP6,SLC16A9,RNF148,AGL,GFRA1,CAND2,RIMS2,NOS3,PCDH10,COL4A4,MGAT4B,FASN,RYR2,AIG1,PRDM1,SDK1,GPR19,DHX32,DAGLA,TEX15,SH3GL2,KIAA0355,FAT1,EMILIN2,CDH17,DISP2,AMPD1,DMXL2,EPHA3,LPCAT2,PLXNA2,NTRK3,OR51B4,CHUK,CANX,NRXN1,COLEC10,KIF21B,DENND3,PCLO,GPR15,COL22A1,NELL2,SPEG,UNC13B,CNKSR3,PROS1,SCN2A,MET,DNAH5,SCN3A,PHLDB2,KCNH5,SHANK2,NLGN4X,AMIGO1,FGFR1,ZNF569,ZNF711,SLC39A14,PRKCB,TMPRSS9,GPR160,LAMB1,CYP2U1,CTTNBP2,STON2,LIFR,ZNF701,CTNND2,CNTN1,OR51B5,MAN2B2,PCDH18,CLGN,KLHL13,TSPAN15,LRP4,BIK,IPO5,CLSTN2,COL4A5,RGS7,KCNC4,COL27A1,NEDD4,FSD1,MAP1A,GPR155,STC2,KIAA0319,TRIM3,PRICKLE2,PCK2,NPTXR,IQGAP3,SMAD6,SYK,MED12L,TMC7,MICAL2,USP2,MPP1,NUAK2,GRID1,RASA3,MARS,MGMT,EBF1,GPR37,FAT4,TERT,DOCK6 |
| 2.050e-03 | -6.19 | hairy_cell_leukaemia | COSMIC cancer mutations | hairy_cell_leukaemia | 1469 | 176 | 17385 | 1698 |
MYCBP2,THOC5,UGT8,DNAJC3,MCOLN3,GATA3,NPM1,CEBPA,IKZF2,DNER,EYA4,EOMES,KCNN2,DNAH6,PPFIA2,FAAH2,SERINC2,MPPED2,COL19A1,ATRNL1,JAKMIP2,RCAN3,OR2W3,TSHR,MARK1,KCNIP3,DCC,NR6A1,ANK2,LRRK2,JPH1,DEPTOR,TTC22,TNS1,MFSD6,GPC6,ARHGEF26,DYRK1B,ENPP1,ITGBL1,NCKAP1L,NCAM2,ARHGAP28,CAB39L,MAGI2,ZNF395,SEC24D,FBXO4,OPHN1,MRPL22,LRRC49,ZNF215,ISYNA1,GPSM2,IL18R1,MTUS1,FRY,BCHE,ZNF440,GATA2,FRAS1,CACNB2,ZIC5,LRP6,SLC16A9,RNF148,AGL,GFRA1,RIMS2,CAND2,NOS3,PCDH10,COL4A4,MGAT4B,FASN,RYR2,AIG1,PRDM1,SDK1,GPR19,DHX32,DAGLA,TEX15,SH3GL2,KIAA0355,FAT1,EMILIN2,CDH17,DISP2,AMPD1,DMXL2,EPHA3,LPCAT2,PLXNA2,CHUK,NTRK3,OR51B4,NRXN1,KIF21B,CANX,COLEC10,DENND3,PCLO,GPR15,SPEG,COL22A1,NELL2,UNC13B,CNKSR3,PROS1,SCN2A,MET,DNAH5,SCN3A,PHLDB2,KCNH5,SHANK2,NLGN4X,AMIGO1,FGFR1,ZNF569,ZNF711,SLC39A14,PRKCB,TMPRSS9,GPR160,LAMB1,CYP2U1,CTTNBP2,ZNF701,LIFR,STON2,CTNND2,CNTN1,MAN2B2,OR51B5,PCDH18,CLGN,TSPAN15,KLHL13,BIK,IPO5,LRP4,CLSTN2,COL4A5,RGS7,KCNC4,COL27A1,NEDD4,FSD1,MAP1A,GPR155,STC2,KIAA0319,PRICKLE2,TRIM3,NPTXR,IQGAP3,PCK2,SMAD6,SYK,MED12L,TMC7,MICAL2,USP2,MPP1,GRID1,NUAK2,RASA3,MARS,MGMT,EBF1,GPR37,FAT4,TERT,DOCK6 |
| 2.065e-03 | -6.18 | GSE29618_BCELL_VS_MDC_UP | MSigDB lists | GSE29618_BCELL_VS_MDC_UP | 169 | 29 | 17377 | 1707 |
CXCR5,MXI1,PNRC1,ZNF395,CKAP2,ST6GAL1,ARID5B,MCTP2,OPHN1,ADD2,COBLL1,JAM3,ISG20,CD37,ABLIM1,IKZF3,BACH2,BACE2,MYC,MARCH3,CLMN,TSPAN13,PIK3C2B,SP140,PTPRCAP,RRAS2,ZFP36L2,RASGRP1,RAB30 |
| 2.065e-03 | -6.18 | GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN | MSigDB lists | GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN | 169 | 29 | 17377 | 1707 |
RUNX2,TTC39B,EBPL,IL15,TMEM65,PTPN13,DSTN,VIM,PRDM1,MFSD6,DOCK5,IL18R1,SMPDL3B,HOPX,GALNT3,ENTPD1,PTPRJ,ASNS,MYADM,EOMES,SOAT2,PCGF2,MYO3B,LRRK1,ARL4D,NRP1,SNX10,ATP2B1,ATP2B4 |
| 2.065e-03 | -6.18 | GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN | MSigDB lists | GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN | 169 | 29 | 17377 | 1707 |
EVL,PDK1,TCP11L2,SIDT1,RNF144A,MPP1,ST6GAL1,RAPGEF4,SELL,NPC2,GRK6,CD7,SATB1,MBNL2,KBTBD11,ID3,ABLIM1,EEF2,RALGPS2,MYC,INPP4B,RGS10,RCN3,TSPAN13,TOX,ST8SIA1,PACSIN1,RRAS2,AMPD1 |
| 2.067e-03 | -6.18 | regulation of cell proliferation | biological process | GO:0042127 | 1684 | 196 | 17256 | 1658 |
LILRB1,GATA3,NPM1,NDRG2,CTBP2,STAT5B,CEBPA,PRKCA,SKI,F3,GSDME,EPCAM,RPS6KA2,TGFBR3,DLX6,ITGB3,TSHR,POU3F3,PDGFRB,TBC1D8,CYP1B1,TNK2,CD55,GCNT2,MEIS2,SKAP2,COL4A3,ACVR1C,TGFA,LRRK2,YAP1,FGF17,SGK2,SAV1,HPSE,NCKAP1L,ERN1,TNFRSF1A,TPM1,NRP1,TNFSF4,PPARGC1A,VASH2,MAGI2,CACUL1,MEF2C,BCL11B,EFNB2,SCN5A,RUNX2,INPPL1,FN1,LGALS3,FBXO4,DHCR24,SLC25A27,TNFRSF10C,FOXG1,CHD5,IGF1R,BCHE,GATA2,MYC,C1QL4,PRKG1,LRP6,ST8SIA1,NOS3,HMGCR,PAK1,FGFR4,ATP5IF1,DISC1,PNP,MSTN,SMARCD3,CALCRL,PRDM1,BEX4,THBS4,CSF1,SH3BP4,CLMN,EGFL7,HOXD13,DHCR7,CDH2,NKX2-8,TESC,SIX2,SFN,PLA2G4A,BTC,ID1,IL15,RBFOX2,COL18A1,NTRK3,BCL6B,DDR1,SCIN,RIDA,SPEG,PLPP1,FABP6,BCL6,DAB2IP,RTKN2,SNAI2,GLI1,IGFBP3,GAB2,INTU,FER,PRAME,PTPRU,MVD,TES,PTPN6,PRKCQ,WNT11,ATF3,SYNJ2BP,CD40,ASPH,FRK,FGFR1,WARS,CAMK2N1,IRS2,SMAD3,CXCL10,IKZF3,PTPRJ,APELA,RBPMS2,PEMT,WWTR1,LAMB1,ITGA2,HPGD,HGF,KLF5,BMPR1A,LIFR,TENM1,MXI1,IGFBP6,BMPR2,CD276,PLAG1,TNFSF13B,GAS6,OVOL2,PKN1,EPHB1,BMP6,PHLDA2,FOXP2,SGK3,TFAP2A,SGK1,KLF9,ERRFI1,IQGAP3,SMAD6,TNFRSF11A,SYK,SPRY2,FES,TRPM4,VEGFC,VAV3,MSX1,KDM5B,RAPGEF2,NR4A1,CRIP2,GAREM1,ZFPM2,GPLD1,CEBPB,PTPRC,DDAH1,FGR,NACC2,TERT,ACER2,AKT3,CTSV,XBP1,MCC,BMP4,SHOX2,PTGES,B4GALT7 |
| 2.072e-03 | -6.18 | bicellular tight junction | cellular component | GO:0005923 | 121 | 22 | 18223 | 1724 |
CGN,AMOTL1,BVES,PARD3B,RAPGEF2,CYTH3,TJP1,JAM3,MAGI3,PATJ,EPCAM,MPP7,MARVELD2,CLDN12,POF1B,LIN7A,MPDZ,YBX3,JAM2,MAGI2,NPHP1,OCLN |
| 2.086e-03 | -6.17 | BZIP_BASIC | prosite domains | PS00036 | 34 | 10 | 12060 | 1278 |
CREB3L2,ATF4,BACH2,JDP2,XBP1,NFE2L1,ATF3,CREB5,BATF,BATF3 |
| 2.091e-03 | -6.17 | cellular response to glucocorticoid stimulus | biological process | GO:0071385 | 56 | 13 | 17256 | 1658 |
FBXO32,MSTN,EIF4EBP1,ASS1,ABCC2,KLF9,ERRFI1,PCK2,ZFP36L2,SMYD3,ATP2B1,DDIT4,HEY1 |
| 2.104e-03 | -6.16 | Cognitive test performance(PMID:20125193) | GWAS genes | Cognitive test performance(PMID:20125193) | 16 | 8 | 2388 | 399 |
GRIK4,ATL1,AFAP1L2,KIAA1217,PLCB1,TBC1D30,KCNB2,ZNF788P |
| 2.117e-03 | -6.16 | perinuclear region of cytoplasm | cellular component | GO:0048471 | 670 | 86 | 18223 | 1724 |
PRKN,DNM3,GALNT6,KIF5A,MYO1B,VAMP8,RHPN2,NDRG2,PRKCA,PRR7,RAC3,NCS1,NOS1AP,MAP7,SLC2A12,PACSIN1,MYRIP,TLR4,PRKACB,LAMP3,TNK2,GAPDH,MEIS2,TGFA,GDPD1,PREX1,PRKAR2B,EML1,SNCA,PATJ,GSN,SH3RF1,ATP7B,ITGA2,LAMB1,PAM,MAGI2,COBL,TENM1,SERINC5,SCN5A,ATP9A,SLK,APBB1,TNFSF13B,HERC5,RASD1,APBA1,NDFIP2,GDPD5,DYNC1I1,MLC1,TPD52L1,SPINK5,SPIRE1,NEDD4,GALNT1,PRKCD,EHD3,STC2,YBX3,MYO6,STXBP1,CKAP4,BDNF,USP2,RAB3B,RAPGEF2,WWC1,SNAP25,RACK1,CLN5,LRAT,CTIF,GALNT3,SH3GL2,PKN3,FAT1,CSF1,SELENOM,PLD1,PTGES,OSBPL6,DOCK6,SHTN1,STOM |
| 2.119e-03 | -6.16 | JAK1 (Janus kinase 1) | protein interactions | 3716 | 114 | 22 | 17029 | 1718 |
PLA2G4A,FER,LRRIQ1,PTPN6,RNF125,NPM1,AGO4,STAT5B,RACK1,DSP,PTPRC,IRS2,IGF1R,TENT5A,GHR,TNFRSF1A,TSHR,IL9R,SYK,FES,PDGFRB,LAMP3 |
| 2.120e-03 | -6.16 | FEVR_CTNNB1_TARGETS_UP | MSigDB lists | FEVR_CTNNB1_TARGETS_UP | 637 | 85 | 17377 | 1707 |
MPZL3,CGN,DUSP8,TTC39B,TRIM16,SCAMP1,FLVCR2,IL15,PSTPIP2,ATP8A1,SYT12,IL13RA1,CEBPA,SPATS2L,PRKCA,FKBP11,CDS1,CYP51A1,TYMP,EPB41L3,FABP6,BCL6,EEPD1,CTTN,SERPINH1,PTPRE,CPE,GATM,PDGFRB,SLC3A2,PFKFB2,MVD,ATF3,COTL1,ATOH1,SGK2,DOCK5,CA13,GNAI1,PYCR1,GABARAPL1,GSN,HLF,TRIM34,WFS1,PLEKHG1,HPGD,P4HA1,CYP2U1,DBP,UNC5B,TTC39A,PCSK5,EFNB2,GNG12,FN1,LGALS3,EPS8,TNFSF13B,CBS,ABLIM1,HMGCS1,SOAT2,BACE2,DSG2,STXBP1,GFI1,DUSP1,TMC7,OPLAH,AGPAT4,LITAF,SLC46A3,NPDC1,MMP15,CEBPB,DDAH1,MFSD9,CLMN,CMPK2,OSBPL6,DIRC2,SFN,DDIT3,OCLN |
| 2.123e-03 | -6.15 | ACACTCC,MIR-122A | MSigDB lists | ACACTCC,MIR-122A | 68 | 15 | 17377 | 1707 |
ZNF827,VAV3,MEIS2,MARK1,BACH2,SLC39A8,ALDOA,SLCO5A1,P4HA1,DLG2,CCNG1,STK24,CPEB1,OCLN,NEGR1 |
| 2.126e-03 | -6.15 | GSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_DN | MSigDB lists | GSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_DN | 177 | 30 | 17377 | 1707 |
CXCR5,INTU,FARP1,COL6A2,VLDLR,FERMT2,PSD3,VIM,SDK1,RAB38,DOCK3,DNER,GPC6,CPEB1,FSTL5,SCIN,NEGR1,LGI2,DEXI,MAP1A,ZNF697,WFS1,ITGB3,SERINC2,SLCO5A1,SQLE,PDE4D,SLC16A10,CKAP4,TBC1D8 |
| 2.126e-03 | -6.15 | GSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EFF_MEMORY_VS_CENT_MEMORY_CD4_TCELL_DN | 177 | 30 | 17377 | 1707 |
KCNV1,TYRO3,VNN2,LPAR2,UGT8,EHHADH,UROS,PLEKHA5,SELL,SMARCD3,NLGN4X,PHACTR2,TNS1,PFN2,SEMA6A,DAGLA,HMGCS1,ASNS,BACH2,ITGA2,SH3BP4,TUFT1,GSTM3,CLMN,KLF9,IPCEF1,APBA2,CAND2,BTRC,TLL2 |
| 2.129e-03 | -6.15 | cellular response to xenobiotic stimulus | biological process | GO:0071466 | 173 | 29 | 17256 | 1658 |
GSTM2,ACSL1,MSTN,CYP2J2,MGST3,GSTM4,ASS1,RYR2,GSTO1,ABCC2,STAT5B,PHGDH,CYP26A1,DDIT4,AHRR,FBXO32,GSTO2,BCHE,EIF4EBP1,GHR,GSTM3,CYP2U1,NCEH1,PPARGC1A,ERRFI1,PCK2,SMYD3,CES3,CYP1B1 |
| 2.137e-03 | -6.15 | BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_UP | MSigDB lists | BUCKANOVICH_T_LYMPHOCYTE_HOMING_ON_TUMOR_UP | 20 | 7 | 17377 | 1707 |
DPY19L2,MYCBP2,SKAP2,IKZF5,GBP1,ZNF521,CYP1B1 |
| 2.137e-03 | -6.15 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | 20 | 7 | 17377 | 1707 |
SPRY4,MOXD1,MSTN,PLK2,ZFP36L2,PKIA,IGFBP3 |
| 2.141e-03 | -6.15 | MULLIGHAN_MLL_SIGNATURE_1_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_1_DN | 224 | 36 | 17377 | 1707 |
NBL1,SIDT1,TRIM16,STXBP6,MCTP2,SSX1,NPM1,LAMC3,STAT5B,ISYNA1,RPL13A,PMAIP1,NOVA2,MCF2L,LRP6,PTPRCAP,TSHR,MAST4,ABCC4,STAT4,EFHC2,ASAP3,DEPTOR,PRKCQ,ATP1B1,CCNG1,C1orf174,PYCR1,SLC7A1,RANBP2,HLF,HPGD,CLMN,EGFL7,HGF,STOM |
| 2.145e-03 | -6.14 | GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 55 | 13 | 17377 | 1707 |
CXCL10,GSTM2,CACNB2,ANK2,RYR2,TRPC1,GSTO1,BMP4,ATP1B1,ASPH,HSPA2,CACNA2D1,SNCA |
| 2.145e-03 | -6.14 | GCM_PTPRD | MSigDB lists | GCM_PTPRD | 55 | 13 | 17377 | 1707 |
FADS1,GPRC5B,PTPRD,BACE1,ZNF565,TTYH2,PLEKHA1,ABHD6,KIF1B,SPIRE1,BTRC,MAP1B,DOCK9 |
| 2.145e-03 | -6.14 | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | MSigDB lists | SAMOLS_TARGETS_OF_KHSV_MIRNAS_DN | 55 | 13 | 17377 | 1707 |
EPCAM,FN1,FGF13,PMEPA1,FHL2,MAOA,NXPH4,SHISA2,SLC6A15,IL13RA1,SPOCK3,LZTS1,FKBP11 |
| 2.150e-03 | -6.14 | V$FOXM1_01 | MSigDB lists | V$FOXM1_01 | 232 | 37 | 17377 | 1707 |
PCSK1N,CHCHD7,ARHGEF11,GPR65,STXBP6,PLAG1,OPHN1,CREB5,ABHD4,FOXG1,TNKS1BP1,HMCN1,MTUS1,FOXP2,CHN2,SLC10A7,TMEM86A,BCL6,JAKMIP2,NCAM1,GAB2,MN1,MEIS2,CRIM1,HNF4G,MARS,SNAP25,ATP1B1,EBF1,NCAM2,MAP2K6,PTK7,ZBTB20,PPARGC1A,SEMA3A,DDIT3,MEF2C |
| 2.153e-03 | -6.14 | pseudomyxoma_peritonei | COSMIC cancer mutations | pseudomyxoma_peritonei | 597 | 80 | 17385 | 1698 |
MYCBP2,PSTPIP2,MSR1,NPM1,ABAT,FAM13A,DOCK3,DNER,HMCN1,SLCO3A1,EYA4,TRPS1,ALDH1L1,SERINC2,CTTN,WWC2,CLVS2,MET,SP140L,PDGFRB,MEIS2,B3GALT1,COL4A3,SPOCD1,PTPN6,ANK2,FGFR1,EML1,AHRR,SMAD3,PRKCB,TDO2,MAP2,PTPRS,HGF,VASH2,TTC39A,HOXB9,PCDH18,MOCOS,FARP1,MRC2,CELSR1,EDA2R,ROBO2,GRB14,SCART1,ESRP1,WDFY4,DYNC1I1,ARHGAP44,NKX6-1,FRY,PDZD7,RPS11,PRKCD,ADCY6,SLC16A9,MPDZ,TBC1D9,IQGAP3,ZFP36L2,KIAA1211,MN1,PCDH10,SYNPO2,SLITRK2,CACNA1E,RAPGEF2,DCHS1,GRID1,AGAP2,PLCB1,HOXA1,MAP1B,PCDHB7,FAT4,PMEPA1,DLG2,CDH2 |
| 2.153e-03 | -6.14 | peritoneum-appendix-other-pseudomyxoma_peritonei | COSMIC cancer mutations | peritoneum-appendix-other-pseudomyxoma_peritonei | 597 | 80 | 17385 | 1698 |
MYCBP2,PSTPIP2,MSR1,NPM1,ABAT,FAM13A,DOCK3,DNER,HMCN1,SLCO3A1,EYA4,TRPS1,ALDH1L1,SERINC2,CTTN,WWC2,CLVS2,MET,SP140L,PDGFRB,MEIS2,B3GALT1,COL4A3,SPOCD1,PTPN6,ANK2,FGFR1,EML1,AHRR,SMAD3,PRKCB,TDO2,MAP2,PTPRS,HGF,VASH2,TTC39A,HOXB9,PCDH18,MOCOS,FARP1,MRC2,CELSR1,EDA2R,ROBO2,GRB14,SCART1,ESRP1,WDFY4,DYNC1I1,ARHGAP44,NKX6-1,FRY,PDZD7,RPS11,PRKCD,ADCY6,SLC16A9,MPDZ,TBC1D9,IQGAP3,ZFP36L2,KIAA1211,MN1,PCDH10,SYNPO2,SLITRK2,CACNA1E,RAPGEF2,DCHS1,GRID1,AGAP2,PLCB1,HOXA1,MAP1B,PCDHB7,FAT4,PMEPA1,DLG2,CDH2 |
| 2.168e-03 | -6.13 | BMPR1B (bone morphogenetic protein receptor type 1B) | protein interactions | 658 | 73 | 16 | 17029 | 1718 |
PAK1,BMPR2,RHOD,RAB6B,RAB38,BMP6,PLEKHB1,CHN1,RAP2A,RASD2,TSC22D1,SRGAP1,BMP4,BMPR1A,SMAD6,RRAS2 |
| 2.172e-03 | -6.13 | response to xenobiotic stimulus | biological process | GO:0009410 | 270 | 41 | 17256 | 1658 |
ACSL1,PDE1B,CYP2J2,ASS1,STAT5B,ABAT,PHGDH,CYP26A1,DDIT4,FBXO32,BCHE,GHR,GSTM3,NCEH1,PCK2,ERRFI1,PRKACB,CES3,CYP1B1,TRDMT1,GSTM2,MSTN,GSTM4,MGST3,HOMER2,RYR2,SLITRK5,ABCC2,GSTO1,PRKAR2B,SDK1,SNCA,AHRR,GSTO2,EIF4EBP1,GNAO1,ASIC1,CYP2U1,OXTR,PPARGC1A,SMYD3 |
| 2.174e-03 | -6.13 | C1_1 | pfam domains | PF00130 | 49 | 12 | 17054 | 1666 |
CHN1,VAV3,CHN2,ARHGEF28,PDZD8,UNC13B,PRKCB,PRKCD,PRKCQ,CDC42BPA,PRKCA,RASGRP1 |
| 2.178e-03 | -6.13 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_UP | 185 | 31 | 17377 | 1707 |
SUSD3,TNIK,VAV3,ARAP2,ATP8A1,CYTH3,DNAJC6,MCOLN3,NPC2,DOCK5,TRPS1,SMAD3,IL17D,CAMK2N1,CD37,SEMA4F,RALGPS2,TRIM34,CNKSR3,EHD3,MAP7,ZBTB20,RNF130,IPCEF1,NRP1,VWA5A,GFI1,MYRIP,PTPRE,SMPDL3A,CYP1B1 |
| 2.178e-03 | -6.13 | Signaling by Robo receptor | REACTOME pathways | R-HSA-376176 | 32 | 9 | 10287 | 971 |
PAK1,EVL,ROBO2,PAK5,CAP2,SRGAP1,ENAH,PFN2,SLIT2 |
| 2.178e-03 | -6.13 | Glycolysis | REACTOME pathways | R-HSA-70171 | 32 | 9 | 10287 | 971 |
PFKFB4,GAPDH,HK1,ENO2,ENO1,PFKFB2,ALDOC,ALDOA,HK2 |
| 2.190e-03 | -6.12 | regulation of secretion | biological process | GO:0051046 | 742 | 95 | 17256 | 1658 |
DOC2A,EXPH5,PRKN,LGR4,TRIM16,SYT12,VAMP8,LILRB1,GATA3,CHUK,ITPR2,ABAT,SYT14,NRXN1,PRKCA,PCLO,PPP1R9A,NCS1,SCIN,UNC13B,KMO,RAB26,KCNS3,MARCKS,RAB27B,MYRIP,TLR4,IL1RAP,RASGRP1,GAB2,FER,GAPDH,CSN2,ACVR1C,PFKFB2,WLS,LRRK2,CHRNA6,CD40,SERGEF,FGFR1,SNCA,IRS2,TRIM9,KCNMB4,GBP1,ASIC1,PAM,OXTR,DISP1,ATG5,SEPT5,TNFSF4,TC2N,MEF2C,FN1,STXBP5L,C1QTNF3,STXBP6,APBB1,ARL2,GAS6,P2RY1,KCNC4,PFN2,BMP6,MCU,NKX6-1,RAB11FIP5,GATA2,SREBF1,SGK1,CADPS2,PCK2,MYO6,STXBP1,TNFRSF11A,SYK,FES,RIMS2,HMGCR,TRPM4,VEGFC,RAB3B,KDM5B,CACNA1E,SYBU,RAPGEF4,SNAP25,TLR6,GPLD1,FGR,ICA1,MAP2K6,XBP1 |
| 2.193e-03 | -6.12 | - | gene3d domains | 3.90.550.10 | 76 | 17 | 8148 | 867 |
CHSY3,GXYLT2,GALNT6,GALNT12,COLGALT2,GALNT17,GALNT13,CHSY1,GALNT14,B4GALNT3,GALNT3,GALNT1,GBGT1,MGAT1,GALNT18,B4GALT7,B4GALT6 |
| 2.195e-03 | -6.12 | REACTOME_SIGNALING_BY_RHO_GTPASES | MSigDB lists | REACTOME_SIGNALING_BY_RHO_GTPASES | 110 | 21 | 17377 | 1707 |
ARHGAP26,VAV3,ARAP2,RHOQ,ARHGEF11,RHOBTB1,RHOD,ARHGAP22,PREX1,OPHN1,OBSCN,FAM13A,RAC3,TIAM2,ARHGAP44,SYDE2,CHN1,CHN2,RASGRF2,SRGAP1,ARHGAP28 |
| 2.197e-03 | -6.12 | ion transmembrane transport | biological process | GO:0034220 | 888 | 111 | 17256 | 1658 |
CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,KCNS3,TRPC1,CNNM2,SLC2A12,STEAP3,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,ABCC4,LRRC8B,SLC9C1,SLC39A8,SFXN4,KCNH5,ATOX1,CHRNA6,SLC25A28,KCND3,ATP1B1,SGK2,ASPH,ATP10D,GJC1,SFXN1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,PRKAA2,KCNV1,ANO10,TMEM63C,SCN5A,SLC6A9,GABRB2,SCN8A,ATP6V1E2,GABRG2,SLC36A4,GAS6,GABRR2,SLC1A3,SLC12A6,SFXN3,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SLC7A11,SCN1B,CACNB2,BHLHA15,KCNMB3,SGK3,SGK1,SLC6A15,NIPAL2,FAM155A,ATP2B1,TRPM4,NDUFA4L2,SLC40A1,SLC37A1,KCNQ3,SLC36A1,CACNA1E,GRID1,RYR2,RASA3,TTYH2,STEAP1,PTPRC,KCNK15,TMCO3,GRIK4,SLC2A6,SLC7A5,GRIN2D,SLC1A5,TRPC3,SLC16A10,DDIT3,ATP2B4,CACNA2D1,ATP1A3,SLC43A1 |
| 2.221e-03 | -6.11 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN | 193 | 32 | 17377 | 1707 |
FADS1,TRPM4,GCA,RHOQ,ALDH2,LGALS3,SCAMP1,DOCK1,MPP1,AGPAT4,BLVRB,CTBP2,NPC2,SAV1,PLEKHB1,GABARAPL1,ARHGEF10L,RTN1,EPB41L3,RPS6KA2,NCKAP1L,PRCP,SLC2A6,RAB31,STEAP3,FHIT,CTTN,NRP1,PTPRE,SYK,FES,RRAGD |
| 2.221e-03 | -6.11 | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP | 193 | 32 | 17377 | 1707 |
MXI1,RUNX2,GRIK2,ESRP1,COL18A1,ADSSL1,PLS3,CFHR1,ARL4D,ERRFI1,STXBP1,PCSK6,ANTXR2,BDNF,EVL,PFKFB2,MGST3,NR4A1,CHRNA6,CR2,C1R,GJC1,ISG20,MAP1B,GSN,DOCK7,PTPRJ,MAP2,PAM,CMPK2,GEM,SFN |
| 2.221e-03 | -6.11 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP | 193 | 32 | 17377 | 1707 |
PLA2G4A,PAK1,COL9A3,RHOQ,TTC39B,PNP,SKAP2,EPS8,MCOLN3,VIM,SLCO3A1,IL18R1,C1orf174,FHOD3,EPDR1,CEBPB,ARHGAP21,TIFA,DOCK7,PRCP,OSBPL5,CDH17,TSC22D1,RCN3,GRB10,LRRK1,TESC,FES,CKAP4,PDGFRB,B4GALT6,MEF2C |
| 2.221e-03 | -6.11 | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | 193 | 32 | 17377 | 1707 |
CXCR5,AMOTL1,FARP1,RUNX2,LGALS3,ST14,UBASH3B,ABHD4,GDPD5,EPDR1,CYP51A1,GPR15,PPFIBP1,SAMD11,MPPED2,PCOLCE2,MED7,NEB,SNAI2,SNX7,PDLIM7,SKAP2,PLEKHA8,PTPN13,LITAF,TTC22,CRYBG3,ID3,CLDN12,MATN2,SLC22A15,NRP1 |
| 2.221e-03 | -6.11 | GSE7460_TCONV_VS_TREG_THYMUS_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_UP | 193 | 32 | 17377 | 1707 |
EXPH5,ANKRD13D,ZHX3,ARHGEF11,ELOVL7,ARHGAP22,TMEM170B,GRK6,BCAN,SATB1,SLCO3A1,KREMEN1,OTUD1,SEC16B,TACC2,ITGB3,SGK1,ST8SIA1,QSOX1,PTPN6,CAP2,RAPGEF4,NPC2,TLR6,SLC39A14,AK1,KCNMB4,GPRC5B,P4HA2,C1orf21,PAM,TNFRSF1A |
| 2.221e-03 | -6.11 | RTTTNNNYTGGM_UNKNOWN | MSigDB lists | RTTTNNNYTGGM_UNKNOWN | 147 | 26 | 17377 | 1707 |
SLC6A9,MSTN,MCTP2,GABRG2,ZIC2,CREB5,ATP1B1,C4orf19,NOVA1,ATP10D,ZIC1,BCL11A,TRPS1,SMAD3,FOXP2,ATPAF2,UNC13B,MAP2K6,KLF5,CAB39L,FHIT,PTPRCAP,NIPAL2,MAST4,ETV1,NOS3 |
| 2.229e-03 | -6.11 | GO_CYTOSKELETON | MSigDB lists | GO_CYTOSKELETON | 1809 | 213 | 17377 | 1707 |
ARHGAP26,CGN,FGF13,KIF5A,ACTL8,PTPN21,NDRG2,TUBE1,NPM1,ENAH,RAC3,SKI,TUBB4A,RPS6KA2,DNAH6,CTTN,PPP2R2B,TLN2,MYRIP,NEB,PRKACB,DBN1,MARK1,ATF4,EML6,KLHL3,KLHL4,ANK2,DSTN,LRMP,FEZ1,TNS1,EFHC1,PRKAR2B,COTL1,INTS6,EML1,GNAI1,TRIM9,GSN,MAP2,WIPF3,PLK2,CCDC146,ALDOA,MAP9,TMOD2,NRP1,DNHD1,TPM1,FRMD5,LATS2,GNG12,INPPL1,DHCR24,OPHN1,LRRC49,SORBS3,GPSM2,DYNC1I1,BBS9,PFN2,FHOD3,SPIRE1,MTUS1,ABLIM1,NAV1,SLC7A11,FRY,SMTN,GAN,FIGN,CKAP4,NOS3,BOD1,EPB41L5,PAK1,MID2,DISC1,RHOQ,PNP,MYO10,FHL2,HIP1,PLS1,CDC42BPA,CPEB1,SPATA7,BAIAP2,MAPKAPK2,PLEKHH2,WDR19,RAI14,DYNC2LI1,FNBP1L,CDH2,FRMPD3,EML5,NEK10,DNM3,ID1,SORBS1,TCTN2,AKAP5,PSTPIP2,MYO1B,LRRCC1,RGS20,PKP2,ADD2,KIF21B,RADIL,TNKS1BP1,FAM110B,PIBF1,DOCK2,TBC1D30,PCLO,PPP1R9A,CTNNA2,SCIN,EPB41L3,TACC2,ALDOC,KAZN,MYO3B,MAP7,MYH15,MARCKS,PDE4D,DNAH5,ZNF365,SNX10,HSPA2,PHLDB2,FER,SSH3,EVL,TMEM67,GAPDH,MYLK3,TUBA1A,SHANK2,VIM,TTLL7,TTC28,DSP,CENPV,GABARAPL1,SNCA,ARMC4,RANBP2,ARHGAP21,IFT81,GYPC,PDLIM3,CCNA1,SEPT5,COBL,MID1,MAST1,TNIK,WASF3,MYO1D,FARP1,CKAP2,ARL2,KIF5C,IGF2BP2,FSD1,RAB11FIP5,MAP1A,GAS2L3,GTF2F2,TFAP2A,ACTA2,SH3PXD2B,DYNC2H1,MYO6,SEPT3,SPRY2,FES,B9D1,PDLIM7,SYNPO2,LCA5,PXN,USP2,MPP1,PTPN13,SYBU,FERMT2,ARHGAP32,CTTNBP2NL,SNTB1,PALLD,PEAK1,MAP1B,ID3,FGR,MYADM,MAP2K6,SVIL,UACA,MYOM2,KIF21A,GEM,KIF1B,NPHP1,FILIP1,STOM,SNPH,TPT1 |
| 2.229e-03 | -6.11 | actin filament bundle organization | biological process | GO:0061572 | 63 | 14 | 17256 | 1658 |
RND2,SORBS1,RND3,RHOBTB1,RHOD,EPS8,MYO1B,ADD2,PLS1,MARCKS,SHTN1,SPIRE1,BAIAP2,PLS3 |
| 2.229e-03 | -6.11 | negative regulation of synaptic transmission | biological process | GO:0050805 | 63 | 14 | 17256 | 1658 |
PRKN,GRIK2,BCHE,PLK2,SHANK2,LRRK2,ASIC1,NLGN4X,STXBP1,ABHD6,PPP1R9A,CBLN1,GNAI1,SNCA |
| 2.243e-03 | -6.10 | GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | 103 | 20 | 17377 | 1707 |
EPS8,ADD2,PFN2,FHOD3,SCIN,SNCA,DKK1,BCL11A,TRIM9,GSN,MYADM,INSIG1,PMEPA1,DACT1,EIF4EBP1,PRKCD,SGK1,TMOD2,SMAD6,SLIT2 |
| 2.254e-03 | -6.10 | appendix | COSMIC cancer mutations | appendix | 598 | 80 | 17385 | 1698 |
MYCBP2,PSTPIP2,MSR1,NPM1,ABAT,FAM13A,DOCK3,DNER,HMCN1,SLCO3A1,EYA4,TRPS1,ALDH1L1,SERINC2,CTTN,WWC2,CLVS2,MET,SP140L,PDGFRB,MEIS2,B3GALT1,COL4A3,SPOCD1,PTPN6,ANK2,FGFR1,EML1,AHRR,SMAD3,PRKCB,TDO2,MAP2,PTPRS,HGF,VASH2,TTC39A,HOXB9,PCDH18,MOCOS,FARP1,MRC2,CELSR1,EDA2R,ROBO2,GRB14,SCART1,ESRP1,WDFY4,DYNC1I1,ARHGAP44,NKX6-1,FRY,PDZD7,RPS11,PRKCD,ADCY6,SLC16A9,MPDZ,TBC1D9,IQGAP3,ZFP36L2,KIAA1211,MN1,PCDH10,SYNPO2,SLITRK2,CACNA1E,RAPGEF2,DCHS1,GRID1,AGAP2,PLCB1,HOXA1,MAP1B,PCDHB7,FAT4,PMEPA1,DLG2,CDH2 |
| 2.261e-03 | -6.09 | regulation of heart rate | biological process | GO:0002027 | 98 | 19 | 17256 | 1658 |
TRPM4,SCN5A,BVES,ANK2,RYR2,PKP2,KCND3,DSP,NOS1AP,IRX5,SCN1B,CACNB2,DSG2,SREBF1,ADRB1,PDE4D,TPM1,SEMA3A,CACNA2D1 |
| 2.262e-03 | -6.09 | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_UP | 170 | 29 | 17377 | 1707 |
FER,LGALS3,SLC36A1,ATP8A1,MLF1,MGAT4B,APBB1,DHCR24,YPEL2,MSRB3,COL18A1,NDRG2,VIM,CTBP2,COTL1,PKN1,SNX9,ASPH,NEO1,CPNE2,GALNT1,HMGCS1,TSC22D1,TRIM3,HPGD,PROS1,NEB,LZTS1,FRMD5 |
| 2.265e-03 | -6.09 | GO_REGULATION_OF_HEART_RATE | MSigDB lists | GO_REGULATION_OF_HEART_RATE | 82 | 17 | 17377 | 1707 |
TRPM4,SCN5A,BVES,ANK2,PKP2,RYR2,DSP,NOS1AP,SCN1B,CACNB2,DSG2,ADRB1,SREBF1,PDE4D,TPM1,SEMA3A,CACNA2D1 |
| 2.272e-03 | -6.09 | chr4q32 | MSigDB lists | chr4q32 | 31 | 9 | 17377 | 1707 |
MSMO1,SH3RF1,RAPGEF2,MAP9,PALLD,CPE,DDX60L,SPOCK3,FSTL5 |
| 2.272e-03 | -6.09 | BCAT.100_UP.V1_DN | MSigDB lists | BCAT.100_UP.V1_DN | 31 | 9 | 17377 | 1707 |
ZNF711,RALGPS2,WISP3,FZD4,KLHL4,DOCK3,TLN2,SERGEF,SNAI2 |
| 2.272e-03 | -6.09 | BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP | MSigDB lists | BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP | 31 | 9 | 17377 | 1707 |
EFEMP1,FAT4,KCNAB1,RECK,PSD3,LIMCH1,PDE8A,GULP1,LEPR |
| 2.274e-03 | -6.09 | GO_PEPTIDYL_TYROSINE_DEPHOSPHORYLATION | MSigDB lists | GO_PEPTIDYL_TYROSINE_DEPHOSPHORYLATION | 96 | 19 | 17377 | 1707 |
SSH3,DUSP8,PTPRU,PTPRD,PTPN13,UBASH3B,PTPN6,DNAJC6,PTPN21,DUSP9,EYA4,PTPRC,PTPRJ,CDC14B,DUSP19,PTPRN2,PTPRS,PTPRE,DUSP1 |
| 2.281e-03 | -6.08 | GO_CALCIUM_ION_TRANSPORT | MSigDB lists | GO_CALCIUM_ION_TRANSPORT | 209 | 34 | 17377 | 1707 |
CACNG3,MCOLN3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,BHLHA15,CACNB2,TRPC1,TMEM37,ATP2B1,TRPM4,GPM6A,SLC3A2,CSN2,ANK2,CACNA1E,JPH1,RASA3,CALCRL,RYR2,ASPH,PTPRC,CACHD1,PRKCB,BBC3,TRPC3,DDIT3,CACNA2D1,ATP2B4,TPT1,DENND5B |
| 2.283e-03 | -6.08 | REACTOME_REGULATION_OF_INSULIN_SECRETION | MSigDB lists | REACTOME_REGULATION_OF_INSULIN_SECRETION | 89 | 18 | 17377 | 1707 |
GNG12,AKAP5,RAPGEF4,PRKAR2B,ITPR2,SNAP25,PRKCA,PLCB1,GNAI1,GNAO1,GNB4,CACNB2,KCNS3,ADCY6,MARCKS,STXBP1,CHRM3,PRKACB |
| 2.283e-03 | -6.08 | KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3 | MSigDB lists | KONDO_PROSTATE_CANCER_HCP_WITH_H3K27ME3 | 89 | 18 | 17377 | 1707 |
RAX,ZNF516,MARK1,EBPL,TRIM16,XYLT1,CR2,CBY1,SNAP25,COL14A1,ZNF438,KCNAB1,FBN1,C12orf60,SAMD11,LIMCH1,ST8SIA1,RASGRP1 |
| 2.291e-03 | -6.08 | forebrain neuron fate commitment | biological process | GO:0021877 | 11 | 5 | 17256 | 1658 |
BCL11B,SATB2,DLX2,GATA2,NKX2-1 |
| 2.291e-03 | -6.08 | xenobiotic catabolic process | biological process | GO:0042178 | 11 | 5 | 17256 | 1658 |
GSTM3,GSTO1,GSTM2,ACSL1,GSTM4 |
| 2.291e-03 | -6.08 | postsynaptic membrane assembly | biological process | GO:0097104 | 11 | 5 | 17256 | 1658 |
NLGN4X,NRXN1,MAGI2,CDH2,LRP4 |
| 2.291e-03 | -6.08 | response to folic acid | biological process | GO:0051593 | 11 | 5 | 17256 | 1658 |
GSN,EEF2,ZNF354A,BCHE,MGMT |
| 2.291e-03 | -6.08 | mitral valve development | biological process | GO:0003174 | 11 | 5 | 17256 | 1658 |
BMPR1A,ACVR1,BMPR2,SMAD6,DCHS1 |
| 2.294e-03 | -6.08 | KRAS.600.LUNG.BREAST_UP.V1_UP | MSigDB lists | KRAS.600.LUNG.BREAST_UP.V1_UP | 265 | 41 | 17377 | 1707 |
COL9A3,KIF5A,FBXO4,CLSTN2,LAMC3,KIF5C,ADAMTS6,DYNC1I1,FAM174B,BMP6,CTNNA2,NELL2,MAGEA3,GULP1,MAGEA6,NCAM1,FAM155B,GFI1,SLIT2,SPRY2,IGFBP3,SH2D2A,OGDHL,WDR25,TTC22,PRDM1,SNAP25,ISG20,DCBLD2,MMP15,CD37,KCNK15,GYPC,TERT,ITGA2,SLCO5A1,TNFSF15,SEMA3A,MAPK10,DDIT3,DENND5B |
| 2.294e-03 | -6.08 | KEGG_MAPK_SIGNALING_PATHWAY | MSigDB lists | KEGG_MAPK_SIGNALING_PATHWAY | 265 | 41 | 17377 | 1707 |
PLA2G4A,GNG12,CACNG3,DUSP8,FGF13,CHUK,PRKCA,CACNB4,RAC3,MECOM,RPS6KA2,CACNB2,MYC,RRAS2,HSPA2,RASGRP1,PRKACB,PDGFRB,DUSP1,PAK1,FGFR4,BDNF,ATF4,NR4A1,RAPGEF2,CACNA1E,FGF12,DUSP9,FGF17,FGFR1,MAPKAPK2,PRKCB,RASGRF2,AKT3,MAP2K6,TNFRSF1A,MAPK13,MAPK10,CACNA2D1,DDIT3,MEF2C |
| 2.296e-03 | -6.08 | glycolytic process through glucose-6-phosphate | biological process | GO:0061620 | 26 | 8 | 17256 | 1658 |
GAPDH,ENO2,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1 |
| 2.296e-03 | -6.08 | glycolytic process through fructose-6-phosphate | biological process | GO:0061615 | 26 | 8 | 17256 | 1658 |
GAPDH,ENO2,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1 |
| 2.296e-03 | -6.08 | outflow tract septum morphogenesis | biological process | GO:0003148 | 26 | 8 | 17256 | 1658 |
ACVR1,BMPR2,SEMA3C,BMP4,BMPR1A,NRP1,ZFPM2,SMAD6 |
| 2.303e-03 | -6.07 | regulation of secretion by cell | biological process | GO:1903530 | 689 | 89 | 17256 | 1658 |
DOC2A,EXPH5,PRKN,LGR4,TRIM16,SYT12,VAMP8,LILRB1,GATA3,CHUK,ITPR2,ABAT,SYT14,NRXN1,PRKCA,PCLO,PPP1R9A,NCS1,UNC13B,KMO,RAB26,KCNS3,MARCKS,RAB27B,MYRIP,TLR4,IL1RAP,RASGRP1,GAB2,FER,GAPDH,ACVR1C,PFKFB2,WLS,LRRK2,CHRNA6,CD40,SERGEF,FGFR1,SNCA,IRS2,TRIM9,KCNMB4,GBP1,ASIC1,PAM,OXTR,DISP1,ATG5,SEPT5,TNFSF4,TC2N,MEF2C,FN1,STXBP5L,C1QTNF3,STXBP6,APBB1,ARL2,GAS6,P2RY1,KCNC4,PFN2,BMP6,MCU,NKX6-1,RAB11FIP5,GATA2,SREBF1,CADPS2,PCK2,STXBP1,SYK,FES,RIMS2,HMGCR,TRPM4,VEGFC,RAB3B,KDM5B,CACNA1E,SYBU,RAPGEF4,SNAP25,TLR6,GPLD1,FGR,ICA1,XBP1 |
| 2.313e-03 | -6.07 | V$ZF5_01 | MSigDB lists | V$ZF5_01 | 225 | 36 | 17377 | 1707 |
EFNB2,LRFN5,SYT12,APBB1,KCTD12,STAT5B,ZIC2,RGS7,SEZ6L2,ARHGAP44,ZNF362,KCTD15,ZNF521,SHF,TMEM132E,PAK1,BCL7A,NR4A1,KCNH5,RNF125,WNT11,KCND3,HOMER3,MMP15,DDAH1,C1orf21,RAB31,NXPH4,TMOD2,HS3ST3B1,TPM1,NKX2-8,KIF1B,DDIT3,BTRC,HS6ST3 |
| 2.316e-03 | -6.07 | GO_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 406 | 58 | 17377 | 1707 |
KCNV1,SCN5A,SLC6A9,CACNG3,SCN8A,MCOLN3,ITPR2,GAS6,SLC1A3,SLC12A6,KCNC4,CACNB4,NCS1,SLC9A7,MCU,MCOLN2,KCNJ4,KCNN2,KCNAB1,SLC30A4,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,SLC6A15,TMEM37,SCN2A,NIPAL2,SCN3A,KCNB2,ATP2B1,TRPM4,SLC40A1,GPM6A,SLC3A2,KCNIP3,KCNQ3,KCNH5,CACNA1E,SLC39A8,ATOX1,RYR2,RASA3,ATP1B1,KCND3,SLC39A14,KCNK15,KCNMB4,ATP7B,KCNG1,SLC1A5,TRPC3,SLC9B1,ATP2B4,CACNA2D1,ATP1A3,DENND5B |
| 2.318e-03 | -6.07 | GTCTTCC,MIR-7 | MSigDB lists | GTCTTCC,MIR-7 | 155 | 27 | 17377 | 1707 |
EPHA3,MOB1B,CHSY3,SLC6A9,ZNF395,RNF144A,ESRRG,FOXN3,BACE1,PLAG1,CYTH3,SHANK2,IGF2BP2,MAPK4,SATB1,PFN2,HPCAL4,DDIT4,IRS2,RNF141,KLF12,PRKCB,OSBPL5,DIRAS1,TMED9,PDE4D,CKAP4 |
| 2.318e-03 | -6.07 | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | MSigDB lists | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | 155 | 27 | 17377 | 1707 |
PDLIM7,QSOX1,RGS16,NBL1,ACSL1,KDM5B,ZNF395,MPP1,SMARCD3,TNS1,CEBPB,CHN1,INSIG1,HPSE,SLC7A5,TNFRSF1A,PROS1,SYNGR3,DHCR7,PTGES,PERP,ABCG1,GAB2,HRASLS,IGFBP3,RRAGD,CYP1B1 |
| 2.318e-03 | -6.07 | GSE13547_WT_VS_ZFX_KO_BCELL_UP | MSigDB lists | GSE13547_WT_VS_ZFX_KO_BCELL_UP | 155 | 27 | 17377 | 1707 |
LATS2,CD55,RAB6B,CACNA1E,CYTH3,KIF5C,ST6GALNAC3,ITPR2,PLEKHA1,CD7,IKZF2,TRPS1,ISG20,RUFY4,EOMES,FRY,PLOD2,AKT3,INPP4B,TOX,INPP5F,TMEM37,PACSIN1,NRP1,TNFSF4,FAM78B,MEF2C |
| 2.323e-03 | -6.07 | GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_DN | MSigDB lists | GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_DN | 178 | 30 | 17377 | 1707 |
MN1,VEGFC,DPP10,RPL26,MYCBP2,GLIPR1L1,CKAP2,FEZ1,SHISA2,FBXO36,MLC1,PLCB1,NAALADL2,ZNF558,NIPSNAP3B,CRYBG3,STEAP1,SPATA7,SUGT1,OR2T33,NAV1,KCNN2,CLDN12,WWTR1,CTTN,THSD1,MMP16,NEB,CTNND2,MME |
| 2.323e-03 | -6.07 | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | 178 | 30 | 17377 | 1707 |
PLA2G4A,TMC7,ARHGAP26,EVL,TTC39B,ABCC4,SKAP2,ATP8A1,UBASH3B,BLVRB,ABAT,FAM198B,ATP1B1,PEAK1,DOCK2,MGMT,QPRT,PLS3,TRPS1,GSN,GRHL1,PEMT,PLXDC2,NCOA7,RGS10,ERRFI1,NRP1,AGL,IL1RAP,CYP1B1 |
| 2.337e-03 | -6.06 | haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 69 | 15 | 17385 | 1698 |
PAK1,FOXP2,MID2,ID3,SLC30A4,MYC,ZIC5,XBP1,TMEM117,NLGN4X,SGK1,PGM2L1,SEMA3C,OXTR,DNAH5 |
| 2.338e-03 | -6.06 | organonitrogen compound biosynthetic process | biological process | GO:1901566 | 1441 | 170 | 17256 | 1658 |
CCDC126,NMNAT3,GXYLT2,ADAL,UGT8,AASS,RECK,UGDH,ASS1,GATA3,ALG1L,NRN1,CEBPA,CHAC1,ABAT,MGAT5B,NHP2,BCAN,AARS,QPRT,TYMP,GSTM3,COG3,ENO1,GALNT18,IL1RAP,PDGFRB,EIF4E3,GCNT2,PLPP2,NFE2L1,HACD1,ZDHHC14,GPC6,PYCR1,ALDOA,BDH2,B3GALT2,DSEL,HS6ST3,PCSK5,UST,CARS,GPT2,MOCOS,ST6GAL1,ELOVL7,RIMKLA,MRPL22,GALNT13,CHSY1,SLC1A3,PHGDH,ADSSL1,PGAP1,RPL13A,RSL24D1,GBGT1,GALNT1,PRTFDC1,EEF2,CNTN4,RPS11,HS3ST5,ADCY6,ST8SIA1,MOXD1,RPS23,CHSY3,RPL26,ATP5IF1,B3GLCT,PNP,MGST3,GSTM4,MGAT4B,EDEM3,SDC3,ST6GALNAC3,GALNT17,CPEB1,NEGR1,GLCE,RIMKLB,GSTO2,RPL28,MFSD2A,HK2,PANK3,AMPD1,PLA2G4A,ELOVL4,LPCAT2,GALNT12,GALNT6,XYLT1,LPIN3,NUDT12,CDS1,PLPP1,ASNS,KMO,ALDOC,ZDHHC6,ZDHHC23,RPL26L1,GATM,NTNG1,RPS13,CTH,ALG10B,VNN2,GAPDH,B3GALT1,GARS,UROS,PFKFB2,MVD,PANK1,ADCY1,GSTO1,PXYLP1,WARS,TPK1,SNCA,PEMT,EIF4EBP1,ALG11,HS3ST3B1,ATG5,PSPH,RPS20,SERINC5,ENO2,BMPR2,CBS,RPL34,FUT9,MGAT1,EIF1,CERS4,ESD,PARP9,B4GALT6,OPLAH,GSTM2,RPL21,ELOVL3,ZDHHC15,OGDHL,MARS,RACK1,GUCY1A2,GALNT14,GPLD1,DPY19L2,GPR37,GALNT3,RPL12,PLOD2,ACER2,SRD5A3,PGM2L1,RPL4,HK1,RPS12,CMPK2,CERS1,B4GALT7,LARP1 |
| 2.338e-03 | -6.06 | GO_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY | 62 | 14 | 17377 | 1707 |
PTCH2,INTU,RUNX2,DISP1,DYNC2H1,CHSY1,SHOX2,PRKACB,FOXA1,GAS1,GPR161,BTRC,ZIC1,GLI1 |
| 2.340e-03 | -6.06 | PRTYPHPHTASE | prints domains | PR00700 | 37 | 10 | 4652 | 458 |
PTPRC,PTPRJ,PTPRD,PTPRU,PTPN13,PTPN6,PTPN21,PTPRN2,PTPRS,PTPRE |
| 2.342e-03 | -6.06 | TRPC4 (transient receptor potential cation channel subfamily C member 4) | protein interactions | 7223 | 15 | 6 | 17029 | 1718 |
TRPC1,TJP1,ITPR2,TRPC3,TNFRSF1A,HOMER3 |
| 2.342e-03 | -6.06 | regulation of gamma-delta T cell activation | biological process | GO:0046643 | 7 | 4 | 17256 | 1658 |
LILRB1,STAT5B,NCKAP1L,SYK |
| 2.342e-03 | -6.06 | pyridine-containing compound catabolic process | biological process | GO:0072526 | 7 | 4 | 17256 | 1658 |
PNP,NUDT12,QPRT,NUDT17 |
| 2.351e-03 | -6.05 | positive regulation of supramolecular fiber organization | biological process | GO:1902905 | 182 | 30 | 17256 | 1658 |
PAK1,TENM1,FER,SYNPO2,EVL,PXN,ID1,MYLK3,GPR65,DSTN,ARL2,SORBS3,WNT11,PFN2,RAC3,BAIAP2,SPIRE1,SCIN,ARHGEF10L,SMAD3,GSN,PPM1E,WIPF3,NCKAP1L,SH3PXD2B,CTTN,TPM1,MET,NRP1,FES |
| 2.352e-03 | -6.05 | MODULE_459 | MSigDB lists | MODULE_459 | 381 | 55 | 17377 | 1707 |
MOCOS,SV2B,ACVR1,ACSL1,FN1,AASS,SLC25A27,BEGAIN,PRDM8,HBE1,SCD,MAPK4,ISYNA1,IL18R1,CBLN1,BAG3,EPHB6,PDE4D,IPCEF1,TBC1D9,LRP3,MED12L,SP140L,KDM5B,TBC1D8B,KLHL4,HOMER2,WDR25,SDC3,OBSCN,PRDM1,AMIGO1,TMEM47,SAV1,FGFR1,RERE,SMAD3,DEXI,SPNS1,GSN,CXCL10,CCBE1,CSF1,MAP2K6,ABI3,WDR19,NCOA7,PLEKHG1,DYNC2LI1,NXPH4,GEM,LARP1,PKIA,SLC43A1,RRAGD |
| 2.359e-03 | -6.05 | peritoneum | COSMIC cancer mutations | peritoneum | 599 | 80 | 17385 | 1698 |
MYCBP2,PSTPIP2,MSR1,NPM1,ABAT,FAM13A,DOCK3,DNER,HMCN1,SLCO3A1,EYA4,TRPS1,ALDH1L1,SERINC2,CTTN,WWC2,CLVS2,MET,SP140L,PDGFRB,MEIS2,B3GALT1,COL4A3,SPOCD1,PTPN6,ANK2,FGFR1,EML1,AHRR,SMAD3,PRKCB,TDO2,MAP2,PTPRS,HGF,VASH2,TTC39A,HOXB9,PCDH18,MOCOS,FARP1,MRC2,CELSR1,EDA2R,ROBO2,GRB14,SCART1,ESRP1,WDFY4,DYNC1I1,ARHGAP44,NKX6-1,FRY,PDZD7,RPS11,PRKCD,ADCY6,SLC16A9,MPDZ,TBC1D9,IQGAP3,ZFP36L2,KIAA1211,MN1,PCDH10,SYNPO2,SLITRK2,CACNA1E,RAPGEF2,DCHS1,GRID1,AGAP2,PLCB1,HOXA1,MAP1B,PCDHB7,FAT4,PMEPA1,DLG2,CDH2 |
| 2.361e-03 | -6.05 | ear morphogenesis | biological process | GO:0042471 | 113 | 21 | 17256 | 1658 |
MSX1,CELSR1,NKX3-2,OTX1,GATA3,MAFB,ATOH1,FOXG1,HOXA1,FGFR1,ZIC1,INSIG1,PDZD7,GATA2,DLX6,PTK7,WDR19,MYO3B,TFAP2A,SPRY2,SIX2 |
| 2.367e-03 | -6.05 | GO_HYDRO_LYASE_ACTIVITY | MSigDB lists | GO_HYDRO_LYASE_ACTIVITY | 43 | 11 | 17377 | 1707 |
CA2,EHHADH,ENO2,UROS,ACO1,FASN,CBS,TGDS,ENO1,CA8,CA13 |
| 2.367e-03 | -6.05 | GO_POTASSIUM_CHANNEL_REGULATOR_ACTIVITY | MSigDB lists | GO_POTASSIUM_CHANNEL_REGULATOR_ACTIVITY | 43 | 11 | 17377 | 1707 |
DPP10,KCNV1,KCNIP3,KCNMB4,KCNAB1,KCNMB3,SGK3,KCNS3,SGK1,AMIGO1,SGK2 |
| 2.373e-03 | -6.04 | PROTEIN_KINASE_ST | prosite domains | PS00108 | 308 | 49 | 12060 | 1278 |
PRKAA2,TNIK,LATS2,ACVR1,DYRK3,SLK,CHUK,MAPK4,GRK6,PRKCA,PKN1,MOK,SPEG,RPS6KA2,PRKCD,SGK3,PRKG1,MYO3B,ACVR2A,PRKG2,SGK1,MAST4,PRKACB,PAK1,MYLK3,MARK1,ACVR1C,LRRK2,NUAK2,OBSCN,PRKCQ,ACVR2B,CDC42BPA,SGK2,GRK3,DYRK1B,MAPKAPK2,PRKCB,PKN3,MAP2K6,AKT3,PLK2,ERN1,MAP3K21,NEK11,BMPR1A,MAPK10,MAP3K20,MAST1 |
| 2.373e-03 | -6.04 | monocarboxylic acid biosynthetic process | biological process | GO:0072330 | 198 | 32 | 17256 | 1658 |
PRKAA2,UST,FADS1,GAPDH,ALOX5AP,ELOVL4,ENO2,PFKFB2,SLC27A2,OLAH,ELOVL7,ELOVL3,OGDHL,FASN,HACD1,SCD,SLC1A3,ABAT,BCAN,ASNS,ALDOC,XBP1,ALDOA,HK2,HPGD,PGM2L1,DSEL,HK1,ENO1,PTGES,OSBPL6,ACSM3 |
| 2.374e-03 | -6.04 | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP | MSigDB lists | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP | 186 | 31 | 17377 | 1707 |
CCDC126,LATS2,RIN2,LCA5,SORBS1,PNP,SIDT1,COBLL1,CR2,PRDM1,CCNG1,FAM81A,INPP1,SLC46A3,HERPUD1,CEBPB,ENTPD1,IKZF3,PTPRJ,GRHL1,GPR160,RBPMS2,RAB31,CERS4,BMPR1A,PLD1,HSPA2,TESC,CSRP2,SNAI2,CRYL1 |
| 2.374e-03 | -6.04 | GSE3982_DC_VS_TH1_DN | MSigDB lists | GSE3982_DC_VS_TH1_DN | 186 | 31 | 17377 | 1707 |
THOC5,IL32,RNF144A,C3orf52,BEGAIN,FASN,MORC4,ABCC2,KCNC4,IL18R1,JAM3,HOPX,SFXN1,CHN1,SLC39A14,BACH2,DNAH6,PMAIP1,STC2,SQLE,TOX,SP140,PDE4D,SYNGR3,GFI1,HOXB9,HSPA2,TESC,SMYD3,FKBP14,PERP |
| 2.374e-03 | -6.04 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | 186 | 31 | 17377 | 1707 |
TCP11L2,FGF13,ACVR1C,RECK,UBASH3B,TNFAIP8L2,CYP4V2,SELL,CALCRL,C20orf194,ADAMTS6,STAT5B,NTRK3,FAM117B,CD40,PRKCA,SESN1,TBC1D16,MTUS1,RERE,SMAD3,CAMK2N1,FBXO32,TECPR1,ZBTB20,SH3BGRL2,IPCEF1,NRP1,CPE,AMPD1,DIRC2 |
| 2.375e-03 | -6.04 | GO_IDENTICAL_PROTEIN_BINDING | MSigDB lists | GO_IDENTICAL_PROTEIN_BINDING | 1152 | 142 | 17377 | 1707 |
MVK,ACVR1,GRIK2,LDLR,LILRB1,ASS1,NPM1,CADM2,CEBPA,CTBP2,ABAT,IKZF2,RBM11,SNX9,SLC9A7,QPRT,KCNN2,AADAT,ITGB3,GSTM3,PTPRE,SLIT2,RASGRP1,ATL1,TNK2,NR6A1,LRRK2,BNIP3L,CR2,PLEKHB1,PYCR1,TRIM9,ENPP1,ALDOA,ERN1,INPP5F,ERCC5,CHMP4C,CRYL1,CARS,FN1,ZHX3,SLK,FBXO4,GPSM2,ADSSL1,GRPEL2,MECOM,PRTFDC1,ZBTB38,IGF1R,PDZD7,PIK3AP1,BCHE,FLRT3,C1QL4,LRP6,BNIP3,NCAM1,STXBP1,HMGCR,MID2,MSTN,GSTM4,HOMER2,FHL2,FASN,RYR2,LHPP,RABAC1,SDK1,CDC42BPA,PLCB1,BAIAP2,PLEKHH2,SH3GL2,CSF1,HEYL,SH3BP4,TESC,NBL1,ID1,AMOTL1,ADD2,COL18A1,MAPK4,CHUK,PPP1R9A,CBLN1,NELL2,TLR3,ASNS,DAB2IP,FHIT,ZNF365,GCA,GAPDH,FZD4,MVD,NLGN4X,VIM,ATF3,CBY1,JAM3,FGFR1,SNCA,BCL11A,SMAD3,IKZF3,GBP1,WWTR1,HPGD,HGF,BMPR1A,MID1,PSPH,ROBO2,LRP4,CBS,TPD52L1,MCU,FOXP2,HMGCS1,BHLHA15,GHR,STC2,TFAP2A,PRKG2,SMAD6,GSTM2,USP2,LEPR,CEBPB,NACC2,TERT,CLDN12,XBP1,LRRK1,BMP4,DDIT3,STOM,ABCG1 |
| 2.378e-03 | -6.04 | TOMLINS_PROSTATE_CANCER_DN | MSigDB lists | TOMLINS_PROSTATE_CANCER_DN | 37 | 10 | 17377 | 1707 |
GSN,ZNF516,MEIS2,LGALS3,SMTN,SCRN1,SVIL,GATM,ATP2B4,GAS1 |
| 2.378e-03 | -6.04 | REACTOME_NETRIN1_SIGNALING | MSigDB lists | REACTOME_NETRIN1_SIGNALING | 37 | 10 | 17377 | 1707 |
UNC5C,ABLIM1,MYO10,DOCK1,DCC,PRKCQ,UNC5B,TRPC3,SLIT2,NEO1 |
| 2.378e-03 | -6.04 | GO_ATP_GENERATION_FROM_ADP | MSigDB lists | GO_ATP_GENERATION_FROM_ADP | 37 | 10 | 17377 | 1707 |
PFKFB4,GAPDH,HK1,ENO2,ENO1,PFKFB2,ALDOC,ALDOA,OGDHL,HK2 |
| 2.386e-03 | -6.04 | Myometrial Relaxation and Contraction Pathways | WikiPathways | WP289 | 158 | 29 | 5312 | 569 |
RGS16,GNG12,ATF4,IGFBP6,ADCY1,RGS20,RYR2,GSTO1,PRKCQ,ATF3,PRKAR2B,GRK6,ITPR2,RGS7,PRKCA,RGS17,PRKCB,GNB4,PRKCD,RGS10,ACTA2,ADCY6,OXTR,PDE4D,PKIA,PRKACB,SFN,IGFBP3,NOS3 |
| 2.387e-03 | -6.04 | GO_RESPONSE_TO_NITROGEN_COMPOUND | MSigDB lists | GO_RESPONSE_TO_NITROGEN_COMPOUND | 826 | 106 | 17377 | 1707 |
PLA2G4A,SORBS1,ID1,PDE1B,TRIM16,AKAP5,ASS1,NPM1,CHUK,STAT5B,ITPR2,ABAT,AARS,TLR3,ASNS,CHRNA5,PMAIP1,AKAP7,GSTM3,PDE4D,SLIT2,PRKACB,FZD1,TRDMT1,FER,SLC3A2,SESN2,UROS,ACVR1C,LRRK2,ADCY1,CHRNA6,PRKAR2B,PRKCQ,ABCC2,ASPH,SNCA,GNAI1,SMAD3,IRS2,GSN,ENPP1,EIF4EBP1,ATP7B,GNB4,PEMT,ITGA2,RGS10,GRB10,OXTR,PPARGC1A,TNFSF4,RRAGD,MEF2C,GNG12,INPPL1,GABRB2,IPO5,ATP6V1E2,SELL,GABRG2,NKX6-1,HMGCS1,CA2,IGF1R,EEF2,ZNF354A,SLC7A11,BCHE,PRKCD,GHR,STC2,SREBF1,ADCY6,LRP6,ERRFI1,CHRM3,DUSP1,PAK1,RHOQ,GSTM2,PXN,NR4A1,RAPGEF2,MGST3,VLDLR,RYR2,SDK1,PLCB1,CPEB1,BAIAP2,MGMT,GPLD1,CEBPB,TRIB3,TERT,FBN1,GNAO1,XBP1,SH3BP4,RAB31,BMP4,TRPC3,TBC1D4,DDIT3,ATP2B4 |
| 2.393e-03 | -6.04 | inorganic ion transmembrane transport | biological process | GO:0098660 | 627 | 82 | 17256 | 1658 |
CACNG3,MCOLN3,ITPR2,SLC2A13,CACNB4,SLC9A7,NCS1,KCNAB1,KCNN2,KCNS3,TRPC1,CNNM2,SLC2A12,STEAP3,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,ABCC4,SLC9C1,SLC39A8,KCNH5,ATOX1,SLC25A28,KCND3,ATP1B1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,SCN5A,GABRB2,SCN8A,ATP6V1E2,GABRG2,GAS6,SLC1A3,SLC12A6,GABRR2,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,BHLHA15,CACNB2,KCNMB3,NIPAL2,FAM155A,ATP2B1,NDUFA4L2,TRPM4,SLC40A1,SLC37A1,KCNQ3,SLC36A1,CACNA1E,TTYH2,RASA3,RYR2,STEAP1,PTPRC,TMCO3,KCNK15,SLC2A6,GRIN2D,TRPC3,CACNA2D1,ATP2B4,DDIT3,ATP1A3 |
| 2.402e-03 | -6.03 | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_DN | MSigDB lists | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_DN | 163 | 28 | 17377 | 1707 |
ARHGAP26,ANTXR2,VAV3,CHCHD7,RHOBTB1,NPM3,MGST3,FOXN3,TMTC4,LHPP,RGS7,UBTD2,ZNF558,CTNNA2,GPLD1,KCNMB4,DOCK7,GPR160,RAP2A,ZNF521,SGK1,LAPTM4B,NXPH4,HS3ST3B1,PDE4D,RPL26L1,GPR161,NOS3 |
| 2.408e-03 | -6.03 | KIF13B (kinesin family member 13B) | protein interactions | 23303 | 101 | 20 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,TBC1D1,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,BAIAP2,NAV1,RALGPS2,SH3BP4,BCL6,MAP3K21,TANC2,OSBPL6,KIF1B,LARP1,GAB2 |
| 2.413e-03 | -6.03 | Collagen | pfam domains | PF01391 | 76 | 16 | 17054 | 1666 |
COL9A3,COL6A2,C1QTNF3,COL4A3,COL4A4,MSR1,COL18A1,COL4A5,COLEC10,COL14A1,COL27A1,COL22A1,COL25A1,CCBE1,COL19A1,COL9A2 |
| 2.415e-03 | -6.03 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | 194 | 32 | 17377 | 1707 |
BCL11B,SERINC5,ACVR1,ID1,BMPR2,SEC24D,UBASH3B,SLK,FAM102B,DDR1,RNF141,TACC2,TSC22D1,SGK1,TSPAN13,KLF9,CTTN,GAB2,TNK2,PXN,GCNT2,SLC39A8,EDEM3,FNDC3A,GSN,IKZF3,NCKAP1L,BDH2,SVIL,P4HA1,FNBP1L,PHC1 |
| 2.415e-03 | -6.03 | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN | 194 | 32 | 17377 | 1707 |
ARHGAP26,DMXL2,QSOX1,RIN2,GCA,ACSL1,LGALS3,FLVCR2,LILRB1,MAFB,KCTD12,CTBP2,NPC2,SNCA,TBC1D2,WARS,RTN1,FGR,PLAGL1,CPVL,MGAT1,PRKCD,BCL6,RAB31,MARCKS,RNF130,SLC1A5,PTPRE,SYK,CKAP4,CEBPD,GAB2 |
| 2.418e-03 | -6.02 | mesenchyme morphogenesis | biological process | GO:0072132 | 44 | 11 | 17256 | 1658 |
SMAD3,MSX1,ACVR1,HEYL,DCHS1,ACTA2,WNT11,BMP4,BMPR1A,SNAI2,HEY1 |
| 2.423e-03 | -6.02 | human chr4q35.1 | chromosome location | human chr4q35.1 | 40 | 9 | 26185 | 1967 |
ACSL1,TLR3,STOX2,PDLIM3,LINC02363,ENPP6,CCDC110,FAM149A,WWC2 |
| 2.423e-03 | -6.02 | human chr6q23.2 | chromosome location | human chr6q23.2 | 40 | 9 | 26185 | 1967 |
VNN2,ENPP1,AKAP7,SGK1,SLC18B1,SLC2A12,RPS12,MOXD1,EYA4 |
| 2.447e-03 | -6.01 | V$PAX4_04 | MSigDB lists | V$PAX4_04 | 202 | 33 | 17377 | 1707 |
CHCHD7,JDP2,PLAG1,PLXNA2,IKZF2,MTUS1,FOXP2,ABLIM1,IGF1R,ABI3BP,COL25A1,MPPED2,BCL6,ZNF521,BEND4,MARCKS,KLF9,SMAD6,MYT1,ETV1,POU3F3,GARS,CCNG1,BCL11A,EBF1,PTPRC,BACH2,GNAO1,ZBTB20,SEMA3C,HOXB9,CRISPLD1,MEF2C |
| 2.448e-03 | -6.01 | PID_P53_DOWNSTREAM_PATHWAY | MSigDB lists | PID_P53_DOWNSTREAM_PATHWAY | 133 | 24 | 17377 | 1707 |
TGFA,BNIP3L,COL18A1,ATF3,CCNG1,PRDM1,TNFRSF10C,SESN1,DDIT4,DKK1,PMAIP1,PCBP4,BCL6,BBC3,STEAP3,HGF,MET,SFN,FOXA1,SNAI2,ZNF385A,PERP,DUSP1,IGFBP3 |
| 2.448e-03 | -6.01 | GROSS_HYPOXIA_VIA_ELK3_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_DN | 148 | 26 | 17377 | 1707 |
CARS,ATF4,PNRC1,KIF5A,ALDH1L2,ITGA6,VLDLR,IL13RA1,ATF3,TIAM2,TRPS1,CEBPB,SLC39A14,CXCL10,ASNS,SLC7A11,MYC,PLK2,XBP1,PRKG2,ZBTB20,ERRFI1,HOXB9,ENO1,SPRY2,CTH |
| 2.451e-03 | -6.01 | fatty acid synthase activity | molecular function | GO:0004312 | 11 | 5 | 17224 | 1680 |
ELOVL4,ELOVL7,OLAH,ELOVL3,FASN |
| 2.458e-03 | -6.01 | ion channel activity | molecular function | GO:0005216 | 427 | 60 | 17224 | 1680 |
KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,SLC9C1,LRRC8B,KCNH5,CACNA1E,JPH1,GRID1,RYR2,CHRNA6,TTYH2,RASA3,KCND3,GJC1,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B |
| 2.462e-03 | -6.01 | GO_PROTEIN_SECRETION | MSigDB lists | GO_PROTEIN_SECRETION | 111 | 21 | 17377 | 1707 |
PNP,AKAP5,WLS,RAPGEF4,GATA3,LILRB1,ACVR2B,CANX,LCP2,TLR6,PCLO,CBLN1,ILDR2,RAB11FIP5,PTPRN2,STEAP3,POU2F2,ARL4D,TLR4,RIMS2,PCSK5 |
| 2.468e-03 | -6.00 | WH1 | pfam domains | PF00568 | 11 | 5 | 17054 | 1666 |
ENAH,EVL,SPRED3,HOMER2,HOMER3 |
| 2.472e-03 | -6.00 | PID_VEGFR1_2_PATHWAY | MSigDB lists | PID_VEGFR1_2_PATHWAY | 69 | 15 | 17377 | 1707 |
MAPKAPK2,PRKAA2,PXN,PTPRJ,SH2D2A,PRKCB,MAP2K6,PTPN6,PRKCD,ITGB3,GRB10,PRKCA,FES,NEDD4,NOS3 |
| 2.474e-03 | -6.00 | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | 171 | 29 | 17377 | 1707 |
SLC3A2,SESN2,DYRK3,PNP,LRRC8B,NR4A1,FERMT2,HECW2,RASD1,ATF3,CHSY1,CHAC1,PHGDH,SNX9,ASPH,F3,TBC1D2,DDIT4,CEBPB,BAG3,PMAIP1,CSF1,SGK1,TNFSF15,GEM,PTPRE,SPRY2,DUSP1,RRAGD |
| 2.474e-03 | -6.00 | GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN | MSigDB lists | GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN | 171 | 29 | 17377 | 1707 |
EML5,CARD6,ZHX3,MYO10,KLHL3,RAB6B,EXOC6B,BIK,PRRG1,KIF5C,TDRKH,ST6GALNAC3,NTRK3,TAF4B,SATB1,TBC1D30,ATP10D,SIPA1L2,SEMA4F,PRKCB,TSC22D1,RGS10,TUFT1,PGM2L1,ZBTB20,DISP1,ST8SIA1,RRAS2,KIF1B |
| 2.480e-03 | -6.00 | Collagen | interpro domains | IPR008160 | 76 | 16 | 18492 | 1811 |
COL22A1,COL9A3,COL6A2,COL4A3,C1QTNF3,COL4A4,CCBE1,COL25A1,MSR1,COL18A1,COL19A1,COL4A5,COLEC10,COL14A1,COL9A2,COL27A1 |
| 2.480e-03 | -6.00 | SREBF and miR33 in cholesterol and lipid homeostasis | WikiPathways | WP2011 | 19 | 7 | 5312 | 569 |
SCD,HMGCS1,PPARGC1A,LDLR,FASN,HMGCR,SREBF1 |
| 2.491e-03 | -6.00 | V$RFX1_02 | MSigDB lists | V$RFX1_02 | 250 | 39 | 17377 | 1707 |
PCSK1N,ANKRD13D,TCTN2,RHOD,TUBE1,LRRC49,TNKS1BP1,CHD5,HPCAL4,TRPS1,TUBB4A,PPM1E,LRRC6,ANKFN1,MPPED2,MORN2,MET,NKX2-1,C3orf67,ATL1,TMEM67,DCDC1,ANK2,MGAT4B,CRIP2,AGAP2,ARRDC4,BATF,TEX9,TBC1D16,EML1,IRS2,GNB4,MPP2,GRIN2D,MAPK10,ATP2B4,ATP1A3,PHC1 |
| 2.497e-03 | -5.99 | WH1/EVH1_dom | interpro domains | IPR000697 | 11 | 5 | 18492 | 1811 |
ENAH,EVL,SPRED3,HOMER2,HOMER3 |
| 2.499e-03 | -5.99 | V$ZIC3_01 | MSigDB lists | V$ZIC3_01 | 242 | 38 | 17377 | 1707 |
MPZL3,ANKRD13B,RASAL2,REL,GABRG2,PRDM8,NRXN1,EPHB1,CYP26A1,MTUS1,NELL2,ZNF362,MAP1A,PCBP4,KAZN,LHX6,GHR,ZNF521,FES,GLI1,NDUFA4L2,PTCH2,PCDH10,ESRRG,LITAF,MAP1B,NEGR1,BCL11A,TSKU,GNAO1,PTK7,GRIN2D,HOXD13,NKX2-8,HOXB9,MAPK10,DOCK6,ATP2B4 |
| 2.501e-03 | -5.99 | V$DBP_Q6 | MSigDB lists | V$DBP_Q6 | 234 | 37 | 17377 | 1707 |
TYRO3,MXI1,SLC6A9,PLAG1,PLXNA2,GPSM2,SNX9,SEMA6A,ARHGAP44,HECTD2,FOXP2,ZIC5,SERINC2,SLC2A12,DAB2IP,GFI1,GFRA1,MN1,GPM6A,KCNIP3,ANK2,SOX21,MGAT4B,DCHS1,NFIA,PACSIN3,MBNL2,SKAP1,GPC6,RERE,GPLD1,NAP1L5,KIAA0355,SVIL,DLG2,PPARGC1A,MID1 |
| 2.503e-03 | -5.99 | glycolytic process | biological process | GO:0006096 | 38 | 10 | 17256 | 1658 |
GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,OGDHL,HK2,PGM2L1,HK1,ENO1 |
| 2.506e-03 | -5.99 | respiratory tube development | biological process | GO:0030323 | 167 | 28 | 17256 | 1658 |
ID1,CELSR1,BMPR2,YAP1,CEBPA,WNT11,ACVR2B,ZFPM2,SAV1,FGFR1,HEG1,FOXP2,RIDA,CCBE1,PTK7,SREBF1,BMPR1A,BMP4,ERRFI1,NKX2-8,DHCR7,SPRY2,FOXA1,PDGFRB,NKX2-1,PCSK5,GLI1,NOS3 |
| 2.516e-03 | -5.99 | Rho_GTPase_activation_prot | interpro domains | IPR008936 | 90 | 18 | 18492 | 1811 |
ARHGAP26,ARAP2,RASAL2,ARHGAP22,PLXNA2,OPHN1,RASA3,ARHGAP32,FAM13A,ARHGAP44,SYDE2,CHN1,ARHGAP21,CHN2,SRGAP1,ARHGAP28,DAB2IP,IQGAP3 |
| 2.517e-03 | -5.98 | HR1_rho-bd | interpro domains | IPR011072 | 7 | 4 | 18492 | 1811 |
RHPN2,RTKN2,PKN1,PKN3 |
| 2.517e-03 | -5.98 | S15_NS1_RNA-bd | interpro domains | IPR009068 | 7 | 4 | 18492 | 1811 |
MARS,GARS,WARS,RPS13 |
| 2.526e-03 | -5.98 | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | 104 | 20 | 17377 | 1707 |
ZNF516,SKAP2,PNRC1,NLGN4X,PRKCQ,GSTO1,TPD52L1,BEX2,GNAI1,GALNT1,IGF1R,BDH2,PTPRN2,DAB2IP,PLD1,MED7,TBC1D4,ESD,STON2,MLLT3 |
| 2.530e-03 | -5.98 | GO_REGULATION_OF_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | MSigDB lists | GO_REGULATION_OF_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 11 | 5 | 17377 | 1707 |
PKP2,RYR2,DSP,DSG2,NOS1AP |
| 2.530e-03 | -5.98 | GO_NEGATIVE_REGULATION_OF_KERATINOCYTE_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_KERATINOCYTE_PROLIFERATION | 11 | 5 | 17377 | 1707 |
EFNB2,INTU,KLF9,SFN,SNAI2 |
| 2.530e-03 | -5.98 | TCCGTCC,MIR-184 | MSigDB lists | TCCGTCC,MIR-184 | 11 | 5 | 17377 | 1707 |
EPB41L5,INPPL1,SLC6A9,PRKCB,FZD1 |
| 2.530e-03 | -5.98 | GO_PERK_MEDIATED_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | GO_PERK_MEDIATED_UNFOLDED_PROTEIN_RESPONSE | 11 | 5 | 17377 | 1707 |
ATF3,ASNS,ATF4,DDIT3,HERPUD1 |
| 2.530e-03 | -5.98 | chr13q31 | MSigDB lists | chr13q31 | 11 | 5 | 17377 | 1707 |
SLITRK5,ABCC4,MBNL2,SOX21,STK24 |
| 2.530e-03 | -5.98 | MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_DN | MSigDB lists | MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_DN | 11 | 5 | 17377 | 1707 |
ASS1,OXTR,RARRES2,PDLIM3,VAMP8 |
| 2.534e-03 | -5.98 | GSE13306_TREG_RA_VS_TCONV_RA_DN | MSigDB lists | GSE13306_TREG_RA_VS_TCONV_RA_DN | 179 | 30 | 17377 | 1707 |
CGN,BTNL9,ESRRG,TGFA,OLAH,TNFAIP8L2,COBLL1,COL18A1,PALLD,CHST10,SCIN,DHX32,AHRR,BEX4,RTN1,NSD1,FBXO32,KCNMB4,FRY,DSG2,MPPED2,SHF,MED7,PPP2R2B,FBXL2,FBXO27,VGLL4,TBC1D4,IL9R,DOCK6 |
| 2.534e-03 | -5.98 | GSE25087_TREG_VS_TCONV_FETUS_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_FETUS_UP | 179 | 30 | 17377 | 1707 |
CREB3L2,GPR63,PPP1R3D,LGALS3,CLGN,BTNL9,LRP4,HIP1,ATP1B1,FAM13A,DOCK5,PLS3,ENTPD1,IRS2,INHBC,HLF,PIK3AP1,ADAMTS3,STARD4,MAP7,PGM2L1,TOX,INPP5F,HS3ST3B1,CTTN,KLF9,SNX10,PERP,NUDT17,TBC1D8 |
| 2.534e-03 | -5.98 | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_DN | 179 | 30 | 17377 | 1707 |
SSH3,MYO1D,SLC3A2,EHHADH,DNAJC3,AGPAT4,ASS1,NRN1,PRKAR2B,PRDM1,GUCY1A2,HPCAL4,NT5DC2,SMPDL3B,FKBP11,PYCR1,QPRT,MMP15,ITGBL1,XBP1,KIAA0513,SLCO5A1,GSTM3,FAM149A,CTTN,TNFRSF17,TSHR,RAB30,CTNND2,CTH |
| 2.534e-03 | -5.98 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_UP | 179 | 30 | 17377 | 1707 |
UST,RPS20,ANO10,ITGB7,EVL,TCTN2,GALNT12,OPHN1,DEPTOR,RAB38,SFXN3,ABHD4,MLC1,BBS9,GALNT3,ID3,PRCP,RGS10,CHRDL1,NBEA,ATRNL1,PTPRS,EPHB6,DYNC2H1,RCAN3,APBA2,SMYD3,ZFP36L2,TBC1D8,PHC1 |
| 2.545e-03 | -5.97 | LUCAS_HNF4A_TARGETS_DN | MSigDB lists | LUCAS_HNF4A_TARGETS_DN | 7 | 4 | 17377 | 1707 |
TRIM9,ABCC4,GAS1,HEY1 |
| 2.545e-03 | -5.97 | KREPPEL_CD99_TARGETS_DN | MSigDB lists | KREPPEL_CD99_TARGETS_DN | 7 | 4 | 17377 | 1707 |
EBF1,KIF21B,INSIG1,STARD4 |
| 2.547e-03 | -5.97 | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_DN | 56 | 13 | 17377 | 1707 |
VNN2,BACH2,RECK,AKT3,PLAG1,COBLL1,PDE8A,ZBTB20,ATP1B1,RRAS2,ATP10D,ATP2B1,MEF2C |
| 2.547e-03 | -5.97 | GO_REGULATION_OF_VESICLE_FUSION | MSigDB lists | GO_REGULATION_OF_VESICLE_FUSION | 56 | 13 | 17377 | 1707 |
ADPRHL1,PLA2G4A,TRIM9,TBC1D8B,TBC1D1,STXBP6,TBC1D9,STXBP1,TBC1D4,TBC1D16,TBC1D30,TBC1D8,TBC1D2 |
| 2.547e-03 | -5.97 | AMIT_SERUM_RESPONSE_60_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_60_MCF10A | 56 | 13 | 17377 | 1707 |
IRS2,FN1,PNRC1,PMAIP1,PLK2,BMP1,TUFT1,MAFB,SGK1,COBLL1,SCD,MBNL2,GAS1 |
| 2.547e-03 | -5.97 | ISSAEVA_MLL2_TARGETS | MSigDB lists | ISSAEVA_MLL2_TARGETS | 56 | 13 | 17377 | 1707 |
GSN,COL9A3,HPSE,IGFBP6,CRIP2,DUSP9,PPP2R2B,SMAD6,DENND3,SLCO3A1,PCDH7,DKK1,SNCA |
| 2.548e-03 | -5.97 | positive regulation of cell projection organization | biological process | GO:0031346 | 348 | 50 | 17256 | 1658 |
EPHA3,TENM1,PRKN,DNM3,FN1,BMPR2,ROBO2,PTPRD,APBB1,EPS8,PLXNA2,NTRK3,PPP1R9A,RND2,SCN1B,GRIP1,DAB2IP,FIG4,PACSIN1,SLIT2,IL1RAP,FES,RIMS2,FZD1,PAK1,BDNF,GPM6A,RHOQ,FZD4,RAPGEF2,SHANK2,VLDLR,FEZ1,AMIGO1,FGFR1,BAIAP2,MAP1B,NEGR1,RIPOR2,PTK7,ITGA2,HGF,SERPINI1,NRP1,SHOX2,MAGI2,FNBP1L,COBL,SHTN1,CNTN1 |
| 2.552e-03 | -5.97 | PID | pfam domains | PF00640 | 26 | 8 | 17054 | 1666 |
NUMBL,TBC1D1,APBB1,GULP1,APBA1,APBA2,TBC1D4,NOS1AP |
| 2.554e-03 | -5.97 | SWEET_KRAS_TARGETS_UP | MSigDB lists | SWEET_KRAS_TARGETS_UP | 76 | 16 | 17377 | 1707 |
MSC,EVL,PMEPA1,P4HA2,MATN2,INPP4B,BMP1,TUFT1,SGK1,FERMT2,TNS1,TPM1,PALLD,ATP2B4,GABARAPL1,IGFBP3 |
| 2.554e-03 | -5.97 | GO_REGULATION_OF_SODIUM_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_SODIUM_ION_TRANSPORT | 76 | 16 | 17377 | 1707 |
SCN5A,FGF12,PKP2,NKAIN2,ATP1B1,SGK2,NEDD4,SCN1B,CNKSR3,SGK3,SGK1,TESC,ATP2B4,STOM,NOS3,CNTN1 |
| 2.561e-03 | -5.97 | MODULE_220 | MSigDB lists | MODULE_220 | 324 | 48 | 17377 | 1707 |
EFNB2,UGT8,ID1,GPR65,EPS8,APBA1,EPHB1,FOXG1,CBLN1,NEO1,RTN1,SPEG,TGFBR3,GHR,TFAP2A,ACTA2,EPHB6,SNAI2,PDGFRB,GLI1,CYP1B1,ITGB7,MSX1,LRMP,FGF12,FEZ1,ROR1,CD40,LEPR,ZIC1,ID3,CXCL10,HLF,SH3GL2,FBN1,WFS1,CSF1,BMP1,SEMA3C,SERPINI1,HOXD13,PAX9,NRP1,NKX2-8,SEMA3A,MID1,CSRP2,MEF2C |
| 2.580e-03 | -5.96 | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | MSigDB lists | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | 141 | 25 | 17377 | 1707 |
RGS16,DYRK3,ID1,SH2D2A,LDLR,RAPGEF4,LRMP,LITAF,PRDM1,GAS6,MAP1B,HEG1,CEBPB,MAPKAPK2,ID3,MSMO1,BCL6,SGK1,MARCKS,POU2F2,VWA5A,ZFP36L2,GATM,AMPD1,ATP2B4 |
| 2.580e-03 | -5.96 | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | 141 | 25 | 17377 | 1707 |
DLGAP1,IL17RD,AMOTL1,FZD4,MYO10,TES,SLC39A8,MVD,UBAC2,SPATS2L,NUP62CL,HEG1,EBF1,ABLIM1,IKZF3,POPDC3,CDC14B,OPN3,LIN7A,NRP1,CMPK2,PSPH,PDGFRB,LARP1,FOXA1 |
| 2.580e-03 | -5.96 | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | MSigDB lists | BOSCO_ALLERGEN_INDUCED_TH2_ASSOCIATED_MODULE | 141 | 25 | 17377 | 1707 |
TTC39B,TBC1D1,SLC39A8,STAT4,KIAA1324L,FAM102B,BATF,SNTB1,LCP2,NDFIP2,TAF4B,SLCO3A1,EOMES,LRRN1,DACT1,CSF1,XBP1,BCL6,HPGD,RAB27B,GFI1,ENO1,RAB30,MEF2C,RRAGD |
| 2.584e-03 | -5.96 | GO_GOLGI_APPARATUS_PART | MSigDB lists | GO_GOLGI_APPARATUS_PART | 846 | 108 | 17377 | 1707 |
PCSK1N,SCAMP1,LPCAT2,GALNT12,GALNT6,ATP8A1,XYLT1,MYO1B,RGS20,RNF24,FAM198B,CHAC1,MGAT5B,BCAN,SNX9,CHST10,SLC9A7,TLR3,SEC16B,RAB26,NBEA,TMED9,PROS1,COG3,PACSIN1,CLVS2,RAB27B,RASGRP1,ATL1,CD55,ERGIC1,B3GALT1,GCNT2,WLS,TGFA,LRRK2,CBY1,RAB38,GPC6,ARHGAP21,GBP1,ATP7B,TNFRSF1A,B3GALT2,PAM,DSEL,HS3ST3B1,RAB30,HACE1,PCSK5,UST,SEC24D,ATP9A,BACE1,ST6GAL1,DHCR24,CLSTN2,GALNT13,CHSY1,GAS6,NDFIP2,RAB11FIP5,GALNT1,GBGT1,FUT9,ABCA5,MGAT1,HS3ST5,SREBF1,LMAN2,ST8SIA1,FIG4,NCAM1,B4GALT6,NOS3,PCSK6,CHSY3,IL17RD,QSOX1,RHOQ,RAB6B,PLEKHA8,CYTH3,SYBU,MGAT4B,GPSM1,SDC3,ST6GALNAC3,SNAP25,ARHGAP32,FNDC3A,B4GALNT3,GALNT14,GLCE,GALNT3,ICA1,SH3GL2,PMEPA1,RND3,ACER2,QPCTL,RAB31,PLD1,CERS1,FNBP1L,MMP16,B4GALT7,ABCG1 |
| 2.584e-03 | -5.96 | GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_M_TUBERCULOSIS_DC_UP | 187 | 31 | 17377 | 1707 |
COL9A3,SERINC5,FARP1,GARS,ALDH2,TES,FOXN3,HOMER2,RAPGEF4,CBS,MARS,HBE1,COL4A5,TTC22,RNF44,AARS,HERPUD1,AK1,RPL12,ASNS,PEMT,PCBP4,MATN2,SREBF1,RGS10,MYOM2,SLC1A5,GFI1,COL9A2,KCNB2,ABCG1 |
| 2.584e-03 | -5.96 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | 187 | 31 | 17377 | 1707 |
EML5,MYCBP2,EVL,PDK1,SCAMP1,MPP1,ST6GAL1,FASN,SELL,KCTD12,PLEKHA1,CD7,SESN1,SATB1,TLR6,RERE,SKI,RNF141,GSN,SIPA1L2,ABLIM1,IGF1R,RALGPS2,WFS1,MYC,RGS10,MAP7,P4HA1,ADCY6,ZBTB20,ABCG1 |
| 2.584e-03 | -5.96 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN | 187 | 31 | 17377 | 1707 |
FAM171B,LANCL3,SIDT1,RNF144A,PLEKHA5,DNAJC6,MCTP2,TNFSF13B,OPHN1,LITAF,ARL2,NTRK3,MFSD6,SLCO3A1,IL18R1,RAB11FIP5,RASSF8,MCOLN2,TEX15,KCNMB4,TGFBR3,SEMA4F,CPVL,BCHE,THBS4,EHD3,STEAP3,HS3ST3B1,PJA1,CTTNBP2,CNTN1 |
| 2.584e-03 | -5.96 | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN | 187 | 31 | 17377 | 1707 |
BCL11B,PAK1,MYO1D,CARD6,HBG2,PDK1,PFKFB2,RAPGEF4,MCTP2,SELL,GABRR2,PLEKHA1,ZBBX,ATP1B1,TBC1D16,TTC28,SLCO3A1,MAGI3,CDR2L,KCNMB4,RALGPS2,ZFYVE28,RASGRF2,C1orf21,TFAP2A,SGK3,ADCY6,ZBTB20,RNF130,RRAS2,AMPD1 |
| 2.584e-03 | -5.96 | GSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN | 187 | 31 | 17377 | 1707 |
ITGB7,RUNX2,ZNF395,TCP11L2,TUBA1A,RHOBTB1,PRSS12,UBASH3B,ZCCHC24,KBTBD11,PFN2,CRYBG3,NEDD4,STK24,TXNDC5,GABARAPL1,RAB11FIP5,GSN,FGR,RND3,GPR155,CNKSR3,RAP2A,RAB31,TSC22D1,ATRNL1,AGL,LIFR,DIRC2,CSRP2,PHC1 |
| 2.584e-03 | -5.96 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | 187 | 31 | 17377 | 1707 |
MOB1B,CELSR1,TTC39B,LITAF,RYR2,PRICKLE1,TDRKH,ADAMTS6,PLEKHA1,COLEC10,CD40,FNDC3A,RAC3,NEO1,QPRT,GPR15,DEXI,KIAA1958,CA2,ITGA2,ZDHHC23,ACVR2A,SERPINI1,TOX,PROS1,COG3,PACSIN1,SMYD3,NTNG1,BTRC,RNF152 |
| 2.584e-03 | -5.96 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 187 | 31 | 17377 | 1707 |
CGN,MSX1,ACVR1,GCNT2,PXN,ID1,RUNX2,SMAD9,BMPR2,MSTN,ACVR1C,LRP4,RYR2,FERMT2,VIM,ACVR2B,BMP6,ZFYVE9,SKI,SMAD3,INHBC,TGFBR3,CHRDL1,BMP1,INHBE,HPGD,ACVR2A,BMPR1A,BMP4,MAGI2,SMAD6 |
| 2.584e-03 | -5.96 | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | 187 | 31 | 17377 | 1707 |
UST,BCL11B,RPL26,CARD6,EVL,ADAL,TCP11L2,SLC37A1,PNRC1,GALNT6,WLS,BACE1,TNFAIP8L2,UBAC2,SATB1,CD53,QPRT,ID3,SIPA1L2,BACH2,RPS11,TNFRSF1A,RCN3,LAPTM4B,RNF130,ST8SIA1,SMYD3,RASGRP1,AMPD1,DIRC2,TPT1 |
| 2.586e-03 | -5.96 | axonal fasciculation | biological process | GO:0007413 | 21 | 7 | 17256 | 1658 |
EPHA3,AMIGO1,CNTN4,NRP1,CELSR3,NCAM2,SEMA3A |
| 2.586e-03 | -5.96 | atrioventricular valve morphogenesis | biological process | GO:0003181 | 21 | 7 | 17256 | 1658 |
BMPR1A,ACVR1,BMPR2,SMAD6,HEYL,DCHS1,HEY1 |
| 2.586e-03 | -5.96 | neuron projection fasciculation | biological process | GO:0106030 | 21 | 7 | 17256 | 1658 |
EPHA3,AMIGO1,CNTN4,NRP1,CELSR3,NCAM2,SEMA3A |
| 2.592e-03 | -5.96 | L1CAM interactions | REACTOME pathways | R-HSA-373760 | 101 | 19 | 10287 | 971 |
PAK1,SCN5A,DNM3,KCNQ3,ANK2,SCN8A,FGFR1,RPS6KA2,SH3GL2,SCN1B,ITGA2,LAMB1,ITGB3,SCN2A,NRP1,NCAM1,SCN3A,SHTN1,CNTN1 |
| 2.606e-03 | -5.95 | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | MSigDB lists | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | 316 | 47 | 17377 | 1707 |
UGT8,TRIM2,CELSR1,SIDT1,GALNT6,GATA3,IGF2BP2,ABAT,PHGDH,FAM174B,SLC19A2,SLC22A18,MYC,REEP1,SREBF1,TFAP2A,NBEA,GSTM3,STEAP3,TSPAN13,ST8SIA1,TBC1D9,GFRA1,LRP12,GPR161,HRASLS,EVL,MYO10,SYBU,FASN,EFHC1,BCL11A,CEBPB,TCF7L1,KCNK15,WFS1,ATP7B,XBP1,WDR19,INPP4B,KLF5,SEMA3C,ATG5,TTC39A,MID1,FOXA1,CSRP2 |
| 2.610e-03 | -5.95 | RAO_BOUND_BY_SALL4_ISOFORM_B | MSigDB lists | RAO_BOUND_BY_SALL4_ISOFORM_B | 485 | 67 | 17377 | 1707 |
CREB3L2,RBFOX2,LRRCC1,NPM1,ADAMTS6,PCLO,RTN1,FKBP9,FBXO32,MAP7,DPP10,GDAP1,TMEM67,SLC3A2,CD55,SKAP2,KLHL23,LRMP,NFE2L1,RNF125,YAP1,ATOH1,TMEM47,GPC6,ENTPD1,MSC,TCF7L1,HLF,ARHGAP28,HS3ST3B1,SPRY4,KLHL31,MLLT3,CHMP4C,EFNB2,RPS20,BMPR2,REL,SLK,RUSC2,IPO5,FAM117B,OVOL2,ZNF219,TNFRSF19,MTUS1,ABLIM1,FUT9,FAM107B,KIAA0408,ST8SIA1,KLF9,TBC1D9,TSPAN9,PTCH2,VAV3,SLC27A2,ARID5B,SHISA2,GPR19,FAM162A,EMILIN2,SH3BP4,RAI14,RPS12,BMP4,CACNA2D1 |
| 2.614e-03 | -5.95 | HELLER_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_SILENCED_BY_METHYLATION_UP | 275 | 42 | 17377 | 1707 |
ID1,CACNG3,CELSR1,IL32,IL15,TSPAN15,REL,OLAH,VAMP8,LDLR,SSX1,MSR1,GATA3,IL13RA1,ABAT,GPSM2,NRXN1,HERC6,PHLDA2,KCNN2,PMAIP1,MAGEA3,BCL6,ST8SIA1,MAGEA6,TNFRSF11A,COL9A2,CYP1B1,LAMP3,IGFBP3,PRAME,ALDH2,WLS,ATF7IP2,MAFB,MBNL2,ISG20,IRS2,CXCL10,MAGEA12,FBN1,GBP1 |
| 2.614e-03 | -5.95 | GO_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | 275 | 42 | 17377 | 1707 |
BCL11B,EFNB2,SCN5A,ID1,BMPR2,GATA3,OVOL2,PRKCA,BMP6,F3,FOXP2,TGFBR3,DLX6,MYC,ITGB3,DAB2IP,KLF9,IQGAP3,ERRFI1,SNAI2,GLI1,INTU,VEGFC,KDM5B,NR4A1,TGFA,YAP1,SYNJ2BP,SAV1,SMAD3,THBS4,XBP1,LAMB1,MCC,EGFL7,BMP4,BMPR1A,VASH2,NRP1,NKX2-8,SFN,MEF2C |
| 2.621e-03 | -5.94 | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | MSigDB lists | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | 563 | 76 | 17377 | 1707 |
NBL1,DUSP8,KIF5A,LDLR,CADM2,MAPK4,TNKS1BP1,SP8,ZFYVE9,F3,CCNJ,TRPS1,SKI,ZNF362,LHX6,MAP7,NBEA,ETV1,PGBD5,COL4A3,ANK2,PREX1,DCBLD2,CAMK2N1,HLF,KLF12,KPNA3,ZNF704,SPRY4,NEUROG2,RAB30,BCL11B,MYO1D,SLC6A9,BMPR2,ARHGEF11,ZNF25,PLAG1,YPEL2,RASL11B,FAM117B,RASD1,CREB5,PFN2,CHD5,EHD3,GAN,TRIM3,KLF9,TBC1D9,TSPAN9,PRR16,SMAD6,MED12L,DPYSL5,SLC40A1,CRIM1,TBC1D8B,SYBU,RAPGEF4,VLDLR,PRRG1,PEX5L,ST6GALNAC3,PLS1,ZFPM2,FNDC3A,PLCB1,FCHO2,AKT3,OSBPL5,KIAA0513,SFMBT1,FNBP1L,PKIA,FOXA1 |
| 2.624e-03 | -5.94 | GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_UP | MSigDB lists | GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_UP | 195 | 32 | 17377 | 1707 |
MOCOS,CACNG3,JDP2,PPFIBP2,NRN1,SFXN3,PRKCA,PHGDH,ABHD4,IL18R1,STK24,RPS6KA2,DLX6,PCBP4,STARD4,DYNC2H1,STXBP1,CHSY3,WISP3,NPM3,FGF12,PLCB1,HEG1,ENTPD1,IKZF3,CLDN12,RBPMS2,ERN1,PCGF2,MYOM2,CAB39L,ATP2B4 |
| 2.626e-03 | -5.94 | regulation of trans-synaptic signaling | biological process | GO:0099177 | 340 | 49 | 17256 | 1658 |
PRKN,CACNG3,SLC6A9,GRIK2,BACE1,SYT12,OPHN1,CLSTN2,BTBD9,SLC1A3,ABAT,NRXN1,KCNC4,PFN2,ABHD6,PPP1R9A,CBLN1,CA2,UNC13B,CNTN4,MAP1A,BCHE,KMO,STXBP1,RIMS2,DBN1,BDNF,RAB3B,RAPGEF2,SHANK2,SYBU,LRRK2,GRID1,NLGN4X,SNAP25,BAIAP2,GNAI1,DKK1,SNCA,GRIK4,KCNMB4,PLK2,ASIC1,MPP2,GRIN2D,OXTR,SEPT5,CDH2,MEF2C |
| 2.626e-03 | -5.94 | modulation of chemical synaptic transmission | biological process | GO:0050804 | 340 | 49 | 17256 | 1658 |
PRKN,CACNG3,SLC6A9,GRIK2,BACE1,SYT12,OPHN1,CLSTN2,BTBD9,SLC1A3,ABAT,NRXN1,KCNC4,PFN2,ABHD6,PPP1R9A,CBLN1,CA2,UNC13B,CNTN4,MAP1A,BCHE,KMO,STXBP1,RIMS2,DBN1,BDNF,RAB3B,RAPGEF2,SHANK2,SYBU,LRRK2,GRID1,NLGN4X,SNAP25,BAIAP2,GNAI1,DKK1,SNCA,GRIK4,KCNMB4,PLK2,ASIC1,MPP2,GRIN2D,OXTR,SEPT5,CDH2,MEF2C |
| 2.643e-03 | -5.94 | GO_REGULATION_OF_KERATINOCYTE_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_KERATINOCYTE_PROLIFERATION | 26 | 8 | 17377 | 1707 |
BCL11B,EFNB2,INTU,YAP1,OVOL2,KLF9,SNAI2,SFN |
| 2.643e-03 | -5.94 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN | 26 | 8 | 17377 | 1707 |
ENTPD1,TEX15,MAFB,HGF,HBE1,NDFIP2,RAPGEF5,ATP10D |
| 2.674e-03 | -5.92 | cellular response to arsenic-containing substance | biological process | GO:0071243 | 16 | 6 | 17256 | 1658 |
MAPK13,GSTO1,ATF3,ATF4,UROS,GSTO2 |
| 2.674e-03 | -5.92 | retina vasculature development in camera-type eye | biological process | GO:0061298 | 16 | 6 | 17256 | 1658 |
ACVR2B,NRP1,BMPR2,FZD4,PDGFRB,CYP1B1 |
| 2.674e-03 | -5.92 | semi-lunar valve development | biological process | GO:1905314 | 16 | 6 | 17256 | 1658 |
GATA3,BMP4,BMPR2,SMAD6,HEYL,HEY1 |
| 2.681e-03 | -5.92 | Apoptotic cleavage of cellular proteins | REACTOME pathways | R-HSA-111465 | 39 | 10 | 10287 | 971 |
GSN,DSG2,PRKCD,PRKCQ,TJP1,VIM,SATB1,DSP,STK24,OCLN |
| 2.689e-03 | -5.92 | V$ERR1_Q2 | MSigDB lists | V$ERR1_Q2 | 243 | 38 | 17377 | 1707 |
SCN5A,KIF5A,XYLT1,NDRG2,ABAT,PRR7,SATB1,HECTD2,PCDH7,RAB11FIP5,PPM1E,NAV1,MAP1A,CACNB2,PCBP4,PRKG2,FAM155B,RAPGEF5,LCA5,GAPDH,NR4A1,GJB2,MGST3,PANK1,GDPD1,ADCY1,WWC1,OBSCN,RNF44,TTLL7,MAP1B,ID3,NXPH4,DLG2,DIRAS1,UNC5B,MBOAT2,MEF2C |
| 2.689e-03 | -5.92 | V$MEF2_03 | MSigDB lists | V$MEF2_03 | 219 | 35 | 17377 | 1707 |
TYRO3,ARHGAP26,GABRB2,NDRG2,FAM81A,PPP2R3A,FOXP2,OPN3,TSC22D1,NBEA,PPP1R3D,USP2,NR4A1,MGST3,SHANK2,TCEA3,FGF12,STRADB,ATF3,PRDM1,MBNL2,DYRK1B,IFT81,KPNA3,PMEPA1,GNB4,HPGD,DIRAS1,DLG2,PPARGC1A,MLLT3,CTNND2,AMPD1,CNTN1,MEF2C |
| 2.689e-03 | -5.92 | GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION | 581 | 78 | 17377 | 1707 |
DNM3,ID1,FGF13,GATA3,LILRB1,PKP2,STAT5B,NTRK3,SEMA6A,SKI,TLR3,ITGB3,BCL6,DAB2IP,TLR4,SLIT2,SEMA6C,SNAI2,NKX2-1,PRAME,MEIS2,DCC,NKX3-2,YAP1,VIM,FGFR1,BCL11A,SMAD3,CXCL10,ENPP1,NRG3,INSIG1,PLK2,GBP1,WWTR1,SEMA3C,INPP5F,DLX2,BMPR1A,NRP1,TNFSF4,SEMA6B,JDP2,UBASH3B,LRP4,CHADL,OVOL2,HOPX,NKX6-1,EFEMP1,CNTN4,SEMA4F,GATA2,ABCA5,MYC,BHLHA15,C1QL4,KIAA0319,ADCY6,GFI1,ZFP36L2,TRPM4,MSX1,MSTN,RAPGEF2,PRICKLE1,MAFB,ZFPM2,DKK1,ID3,TRIB3,XBP1,BMP4,SEMA3A,DDIT3,FOXA1,SIX2,ABCG1 |
| 2.694e-03 | -5.92 | cellular amino acid biosynthetic process | biological process | GO:0008652 | 78 | 16 | 17256 | 1658 |
GPT2,SERINC5,ASNS,RIMKLB,PLOD2,AASS,RIMKLA,ASS1,CBS,SLC1A3,ABAT,PHGDH,GATM,PSPH,PYCR1,CTH |
| 2.695e-03 | -5.92 | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP | 149 | 26 | 17377 | 1707 |
TRPM4,WASF3,QSOX1,MID2,CD55,PTPRU,GSTM4,ZDHHC15,TCEAL3,IGF2BP2,SNTB1,NUP62CL,FHOD3,RERE,CAMK2N1,FKBP9,KIAA0355,MAP2K6,ADCY6,PAX9,SERPINH1,TNFSF4,APBA2,CDH2,PURG,MED12L |
| 2.695e-03 | -5.92 | CTTTGCA,MIR-527 | MSigDB lists | CTTTGCA,MIR-527 | 227 | 36 | 17377 | 1707 |
CREB3L2,BCL11B,EFNB2,ACVR1,KLHL13,PLXNA2,ADD2,PRKCA,NOVA1,MCU,TBC1D19,NBEA,COL19A1,MARCKS,FAM78B,PFKFB4,DPP10,ANTXR2,FZD4,SOX21,CACNA1E,SATB2,ATP11A,ZFPM2,FNDC3A,MBNL2,PLCB1,ZIC1,KPNA3,KLF12,PMEPA1,C1orf21,SFMBT1,KIF1B,NR3C2,MEF2C |
| 2.698e-03 | -5.92 | MAST3 (microtubule associated serine/threonine kinase 3) | protein interactions | 23031 | 109 | 21 | 17029 | 1718 |
PRKAA2,CGN,PHLDB2,RASAL2,PTPN13,PLEKHA5,PKP2,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,YBX3,TANC2,OSBPL6,KIF1B,LARP1,BTRC,CKAP4,GAB2 |
| 2.703e-03 | -5.91 | CTACTGT,MIR-199A | MSigDB lists | CTACTGT,MIR-199A | 172 | 29 | 17377 | 1707 |
DPP10,GPM6A,MEIS2,FN1,ANK2,PLAG1,VLDLR,EDEM3,FGF12,CALCRL,ATF3,ATP1B1,NOVA1,HECTD2,DCBLD2,RNF141,ARHGAP21,PLOD2,TACC2,AKT3,EHD3,C1orf21,SLCO5A1,ACVR2A,MET,ETV1,FNBP1L,LIFR,SEMA6C |
| 2.703e-03 | -5.91 | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP | 172 | 29 | 17377 | 1707 |
RIN2,FARP1,ID1,ABCC4,RNF145,ZNF395,DEPTOR,COBLL1,TNS1,CBY1,SLC12A6,PEAK1,SLC19A2,SPIRE1,SPATA7,ID3,CPNE2,RPS6KA2,IGF1R,LRRC6,BCHE,TSPAN13,HGF,MARCKS,FIG4,GEM,VWA5A,TBC1D8,SLC43A1 |
| 2.703e-03 | -5.91 | GSE10325_BCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_BCELL_VS_MYELOID_UP | 172 | 29 | 17377 | 1707 |
CXCR5,BCL7A,ITGB7,EVL,SIDT1,ST6GAL1,ARID5B,SYBU,SETBP1,CR2,SKAP1,SEL1L3,DSP,ISG20,BCL11A,ID3,ABLIM1,ASNS,BACH2,EHD3,MAPK13,TSPAN13,PIK3C2B,PJA1,SP140,PTPRCAP,RRAS2,RASGRP1,PRKACB |
| 2.707e-03 | -5.91 | intracellular | cellular component | GO:0005622 | 14533 | 1419 | 18223 | 1724 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,KIAA1217,BCAN,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,SMIM20,EIF4E3,KLHL23,DCC,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,FGF17,INTS6,PYCR1,ZNF788P,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,INPP5F,TPM1,DNHD1,VASH2,SCN5A,ZNF25,TJP1,BTBD9,GPSM2,BBS9,FOXG1,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,TOX,CADPS2,FAM84B,ALPK1,DENND1C,MOXD1,FIGN,ZNF385A,ARID5B,ZNF605,FHL2,FASN,HIP1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,SELENOM,CLMN,LAPTM4B,HOXD13,CDH2,SHTN1,GVINP1,DOCK9,MTG1,TFCP2L1,SCAMP1,SUGCT,ABHD13,ADD2,MAPK4,TLR3,ALDH1L1,MAGEA3,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,EBPL,PFKFB2,ADM2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ARHGAP21,PDLIM3,WFS1,LAMB1,RAB30,CGB2,ANKRD13B,WDR17,GCAT,CKAP2,BACE1,PLAG1,FZD8,ESRP1,BIK,UBAC2,CBS,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,OPLAH,LZTS3,RAB6B,RASA3,AK4,ATP11A,NSD1,RPL12,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,PHC1,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,MGAT5B,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,SEC16B,AADAT,ITGB3,TBC1D32,TMEM143,JAKMIP2,ENO1,RAPGEF5,ZNF391,PGBD5,DBN1,KCNIP3,MARK1,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,SESN1,SPNS1,DYRK1B,TRIM9,TCF7L1,INSIG1,KLF12,ERN1,AHNAK2,CIART,NEUROG2,TC2N,CACUL1,RRAGD,LONRF1,TYRO3,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZNF215,ZIC2,PFN2,DOK5,FHOD3,SPIRE1,RNF180,GALNT1,NUMBL,ZBTB38,ZNF440,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,B3GLCT,MGAT4B,GPSM1,STRADB,MAFB,OBSCN,KHDRBS2,BAIAP2,TBC1D2,PLD1,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,MYH15,SNAI2,IGFBP3,RPS13,INTU,LRRC8B,TMEM65,TDRD3,PRDM13,ACO1,RNF125,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,KIZ,DYRK3,NECAB2,BMPR2,PAK5,KLHL13,MCTP2,RASD1,PRDM8,USP30,TTC1,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,SYK,ATP2B1,CES3,PCSK6,DUSP1,FOXN3,CRIP2,PRICKLE1,FERMT2,EXOG,PALLD,ILDR2,MGMT,HOMER3,DKK1,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,PLBD2,LDLR,VAMP8,PRKCA,HECTD2,SLC9A7,TRPS1,TYMP,ZFYVE28,PALD1,KCNS3,NDUFB8,THSD1,GLDC,GDAP1,ERGIC1,KLHL3,WISP3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,BMP1,DSEL,MAPK13,SERPINI1,SPRY4,NRP1,KLF8,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,HERC6,APBA1,TNFRSF19,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,MYC,SREBF1,PRKG1,GRIP1,MAST4,COL9A2,GPR161,BOD1,RPL26,DISC1,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,PLEKHH2,PELI2,THBS4,CECR2,WDR19,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,RHOD,CCDC110,MSR1,COL14A1,DDR1,TIAM2,ZFYVE9,CCDC120,SPEG,ASNS,ERG28,ZNF438,POU5F1B,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,ATF3,SATB2,CBY1,ATP1B1,PYGO1,ATOH1,TRIQK,ATP10D,ISG20,SNCA,PATJ,ZNF711,IKZF3,BEX3,TDO2,CCNA1,ZNF704,HPGD,MID1,STON2,PURG,COBL,HACE1,MYO1D,IGFBP6,EPS8,KIF5C,HERC5,NDFIP2,TPD52L1,INPP1,PHLDA2,ADGRB2,GSAP,IRX5,GPR155,AFF2,RMDN2,DYNC2H1,CERS4,TBC1D9,ERRFI1,SMAD6,B4GALT6,SLC40A1,VAV3,PXN,ALDH2,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,TMEM126A,ZDHHC15,UCHL3,HOXA1,ZFP62,TERT,MCC,SVIL,LRRK1,CERS1,DDIT3,LARP1,ACSL1,UGT8,ACTL8,PTPN21,HMCN1,CHST10,GSDME,ADPRHL1,PPM1E,CNNM2,CTTN,MYRIP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,OXTR,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,SCART1,STXBP6,FBXO4,SCD,CHSY1,SPINK5,EEF2,SLC30A4,ZNF354A,INAVA,CAND2,CEBPD,SNX7,ZNF629,HBG2,ATP5IF1,PODXL2,RHOQ,GSTM4,SDC3,STEAP1,HERPUD1,RIPOR2,PLAGL1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,FNBP1L,NKX2-8,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,ERO1B,PPFIBP1,KAZN,REEP1,FABP6,ACVR2A,FHIT,PROS1,TMEM120B,SP140L,ALG10B,PRAME,ANTXR2,PTPN6,MVD,C3orf52,TCEAL3,CD40,CENPV,ZNF569,BCL11A,BATF3,CAMK2N1,ARMC4,ZNF93,TRIM34,KPNA3,EIF4EBP1,RBPMS2,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,SLX1B,FAM117B,IGF2BP2,COL4A5,OVOL2,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,IPCEF1,TESPA1,RBMS2,PNMA2,USP2,KDM5B,HNF4G,SYBU,CCDC184,ASAP3,PEAK1,GALNT14,TLR6,NAALADL2,LRAT,CTIF,DPY19L2,SUGT1,ICA1,EDA,RND3,ACER2,CTSV,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,PCDH7,EPDR1,BAG3,TGFBR3,PPP1R26,FBXO32,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,ZBED9,NKX2-1,MEIS2,SMAD9,GJB2,TGFA,CAP2,WLS,HACD1,ELMOD1,MSRB3,F12,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,CRYL1,LPP,MEF2C,CARS,LATS2,GNG12,CYP2J2,SLK,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,ZIC5,PRELID2,ST8SIA1,NCAM1,ZNF518B,STXBP1,GLIS1,AGL,FMNL2,GFRA1,RPS23,HMGCR,FADS1,BDNF,ENAM,SLC37A1,PNP,MYO10,STAT4,MGST3,CALCRL,SMARCD3,RYR2,PLS1,TAF4B,MBNL2,CPEB1,DHX32,BEX4,SH3GL2,CDH17,FBXO27,CSRP2,BTC,NUDT10,DNM3,ZNF516,TMSB15A,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,LCP2,NRXN1,COLEC10,TXNRD3,CDS1,GPR15,EPB41L3,EEF1AKMT2,KMO,CNKSR3,DACT1,COL25A1,RTKN2,PJA1,RAB27B,SYNGR3,JAKMIP3,ARL4D,PERP,DOCK8,SCN3A,SSH3,GARS,FZD4,NKX3-2,KCNH5,NPM3,ATF7IP2,PXYLP1,RAB38,TTC28,FGFR1,METAP1D,IRS2,GYPC,ZNF697,PEMT,WWTR1,PLEKHG1,INPP4B,PAM,ALG11,P4HA1,RCN3,TNFSF15,DBP,KLHL31,HOXB9,SERINC5,FARP1,EDA2R,IPO5,P2RY1,CREB5,PKN1,TSPAN17,COL27A1,NEO1,BHLHA15,MCF2L,GAS2L3,MORN2,MYO6,FES,ULBP1,LCA5,CLYBL,RAPGEF2,ELOVL3,RACK1,SNTB1,PTPRC,GALNT3,TRIB3,ID3,GNAO1,AKT3,XBP1,OSBPL5,HK1,SHOX2,DOCK6,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,NUP62CL,NOVA1,FKBP9,KCNAB1,EOMES,KCNN2,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,CD55,GCNT2,SLC3A2,ABCC4,GDPD1,PLEKHA1,TCERG1L,BATF,PLEKHB1,MAP2,P4HA2,GNB4,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,UBASH3B,SETBP1,MLC1,PGAP1,KIAA1958,PRTFDC1,SEMA4F,IGF1R,ABCA5,GATA2,BCHE,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,FGFR4,CHSY3,MID2,SLC27A2,RNF170,HOMER2,TCEA3,SPATA13,PPFIA4,PDE8A,LDHD,NAP1L5,MAPKAPK2,ATPAF2,CSF1,HEYL,MFSD2A,PANK3,TESC,SIX2,SFN,MME,PRKN,AKAP5,LPCAT2,RBFOX2,XYLT1,ZNF83,RNF24,FAM198B,LPIN3,SEZ6L2,KBTBD11,PCLO,CTNNA2,CYP26A1,FAM131B,RIDA,SLC22A17,ZDHHC6,LHX6,MYO3B,ADGRL1,CLVS2,SCN2A,ZNF488,GLI1,CTH,EVL,EVA1A,TMEM67,TUBA1A,UROS,NOP53,FGF12,GSTO1,RARRES2,FRK,ETNPPL,JAM3,SMAD3,RANBP2,NRG3,GBP1,ABI3,ITGA2,SEPT5,ZNF701,MAN2B2,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,MOB1B,MICAL2,PPP1R3D,NUGGC,LITAF,NUAK2,FNDC3A,MAP10,MKX,FAT4,L3MBTL4,FMO4,ZNF214,ZNF808,DLG2,MYRF,RPL4,PAX9,TBC1D4,FILIP1,CGN,MYCBP2,PPP4R4,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,RAC3,DACH2,AARS,STK24,NCS1,MOK,SLC22A18,CHRDL1,GSTM3,SP140,PACSIN1,VWA5A,RCAN3,TBC1D8,DCDC1,EML6,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,DESI1,MEF2B,AGO4,TNS1,SLC25A28,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,SFXN1,HLF,NCKAP1L,PLK2,RASGRF2,ENTPD7,CCDC181,B3GALT2,SPART,LZTS1,ZBED8,INPPL1,ALOX5AP,CELSR1,EHHADH,ZHX3,GABRB2,SCN8A,OPHN1,SLC25A27,GTF2IRD1,ISYNA1,DYNC1I1,ADSSL1,CHD5,NIPSNAP3B,RPL13A,MYORG,MECOM,MCOLN2,GBGT1,NAV1,PDZD7,PIK3AP1,MSMO1,PRELID1,RUNDC3B,MPDZ,RIMS2,RNF152,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,COLGALT2,RABAC1,C4orf19,PLCB1,FAM162A,ZNF558,VPS37D,PMEPA1,PKN3,IQSEC2,AMPD1,ACSM3,PLA2G4A,FRMPD3,EPHA3,AMOTL1,PCSK1N,RASAL2,ELOVL4,RNF144A,GPR65,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,TBC1D30,TMEM53,ZNF827,STARD4,NBEA,SCRN1,DAB2IP,NAP1L3,MARCKS,SERPINH1,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,ZNF396,PRKCB,ASIC1,MAP3K21,KLF5,GRB10,HS3ST3B1,ATG5,MAPK10,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,MXI1,ANKRD13D,GLIPR1L1,ATP9A,CLBA1,CCNJL,ARL2,RGS7,SELENOP,GDPD5,SLC35G2,NEDD4,HOPX,KDM7A,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,PRKG2,PHYKPL,FIG4,YBX3,SEPT3,GFI1,SPRY2,PFKFB4,SYNPO2,ARAP2,HYKK,MPP1,CTTNBP2NL,GUCY1A2,ZNF714,SKAP1,ZIC1,GPLD1,CEBPB,FGR,PCGF2,PGM2L1,TUFT1,GRIN2D,MYOM2,B4GALT7,OCLN,ATP1A3,NUDT17,EXPH5,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,ABAT,CACNB4,RBM11,DNER,ABHD4,IKZF2,CEP85L,QPRT,FKBP11,CYP51A1,ARHGEF10L,RTN1,TUBB4A,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,HRK,EPHB6,PTPRE,GALNT18,FANK1,SLIT2,RASGRP1,PRKACB,ATL1,CAPN5,ZNF565,ROR1,RNF44,SERGEF,GRK3,EML1,AK1,NCAM2,NCOA7,C8orf88,APBA2,SLC9B1,BCL11B,UST,FN1,SEC24D,JDP2,RIMKLA,ELOVL7,YPEL2,CYP4V2,ATP6V1E2,GALNT13,SATB1,PHGDH,ADGRG6,DDIT4,CA2,RPS11,EBF4,NCEH1,MORN4,BARX1,NOS3,RAX,IL17RD,MSTN,SH2D2A,PARD3B,EDEM3,WWC1,DUSP9,GALNT17,PRDM1,LHPP,B4GALNT3,AMDHD1,GLCE,FCHO2,RAI14,HK2,DIRC2,CREB3L2,EML5,ZSWIM5,NEK10,IL15,PLEKHA5,MORC4,TDRKH,BCL6B,LACC1,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,POU2F2,MET,ZNF460,HSPA2,GCA,PHLDB2,FER,TES,SYNJ2BP,DOCK5,TTLL7,C1orf174,WARS,TPK1,MSC,LMLN,BACH2,FAAP20,SOHLH2,CYP2U1,PSPH,TNIK,PRSS16,CLGN,REL,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,EHD3,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,OGDHL,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,MAP1B,RERE,GPR37,TIFA,MYADM,NACC2,GCSAM,MPP7,PRCP,MAP2K6,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,STOM,SNPH |
| 2.710e-03 | -5.91 | Adipogenesis | WikiPathways | WP236 | 131 | 25 | 5312 | 569 |
GATA3,STAT5B,CEBPA,SCD,LPIN3,CYP26A1,CEBPB,EBF1,IRS2,SMAD3,ID3,TRIB3,GATA2,WWTR1,BMP1,SREBF1,KLF5,BMP4,PCK2,PPARGC1A,LIFR,DDIT3,CEBPD,MEF2C,FZD1 |
| 2.715e-03 | -5.91 | LIM | pfam domains | PF00412 | 70 | 15 | 17054 | 1666 |
PDLIM7,MICAL2,ABLIM1,PXN,PDLIM3,TES,CRIP2,LHX6,LMCD1,FHL2,PRICKLE1,PRICKLE2,LIMCH1,CSRP2,LPP |
| 2.718e-03 | -5.91 | MRAP2 (melanocortin 2 receptor accessory protein 2) | protein interactions | 112609 | 55 | 13 | 17029 | 1718 |
UST,FGFR4,ACVR1,MYADM,BMPR2,SLC22A18,ACVR2A,PTPRS,STEAP3,ACVR2B,GRK6,BMPR1A,LRP12 |
| 2.731e-03 | -5.90 | MAP2K6 (mitogen-activated protein kinase kinase 6) | protein interactions | 5608 | 31 | 9 | 17029 | 1718 |
MAPKAPK2,TLR3,MAP2K6,STAT4,LRRK2,MAPK13,RACK1,PKN1,MAP3K20 |
| 2.735e-03 | -5.90 | embryonic organ development | biological process | GO:0048568 | 418 | 58 | 17256 | 1658 |
THOC5,ACVR1,RUNX2,CELSR1,ST14,OTX1,GATA3,CEBPA,OVOL2,FOXG1,EFEMP1,IRX5,SETDB2,EOMES,PDZD7,GATA2,DLX6,TFAP2A,MYO3B,LRP6,SPRY2,GLI1,MICAL2,MSX1,NKX3-2,RYR2,YAP1,MAFB,WNT11,SATB2,PRDM1,ATOH1,RARRES2,ZFPM2,HOXA1,FGFR1,ZIC1,CEBPB,SMAD3,ID3,INSIG1,FBN1,PTK7,RBPMS2,APELA,WDR19,PCGF2,DLX2,BMPR1A,BMP4,VASH2,SHOX2,COBL,MMP16,SIX2,MEF2C,PCSK5,HEY1 |
| 2.736e-03 | -5.90 | NAGASHIMA_NRG1_SIGNALING_DN | MSigDB lists | NAGASHIMA_NRG1_SIGNALING_DN | 50 | 12 | 17377 | 1707 |
DMXL2,PPP1R3D,ZNF362,HMGCS1,RALGPS2,FUT9,MAFB,PGAP1,MID1,GPLD1,F3,DDIT4 |
| 2.754e-03 | -5.89 | BMPR1A (bone morphogenetic protein receptor type 1A) | protein interactions | 657 | 68 | 15 | 17029 | 1718 |
FAM171B,ACVR1,RUNX2,BMPR2,LRRIQ1,MYC,LITAF,TSC22D1,BMPR1A,BMP4,SMAD6,BMP6,TSPAN17,NEDD4,PDGFRB |
| 2.763e-03 | -5.89 | E2F1_UP.V1_DN | MSigDB lists | E2F1_UP.V1_DN | 180 | 30 | 17377 | 1707 |
PLA2G4A,FER,HBG2,AVPI1,RUNX2,SCAMP1,EPS8,CRIP2,RASA3,ITPR2,F3,RAB11FIP5,EBF1,TRIB3,BAG3,ABLIM1,HMGCS1,PLK2,CSF1,MYC,XBP1,GHR,BCL6,SGK1,ZBTB20,ARL4D,TSHR,GFRA1,STOM,CYP1B1 |
| 2.763e-03 | -5.89 | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN | MSigDB lists | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN | 180 | 30 | 17377 | 1707 |
BCL7A,ARAP2,EVL,RNF144A,NR6A1,GALNT6,BACE1,NSUN6,NPM1,ADAMTS6,CD7,TTC28,DOCK2,CHST10,SYDE2,SKI,SMAD3,CD37,KCNMB4,MFSD9,IGIP,CDC14B,ABI3,RUNDC3B,HS3ST3B1,POU2F2,ARL4D,KIF1B,SLC16A10,AMPD1 |
| 2.763e-03 | -5.89 | GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_UP | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_UP | 180 | 30 | 17377 | 1707 |
CHSY3,BCL11B,ID1,IL32,LGALS3,ACVR1C,LSM11,FOXN3,NDRG2,VIM,ATF3,CTTNBP2NL,DNER,DDX60L,COL27A1,SCIN,ZFP62,RTN1,ID3,CXCL10,TIFA,LRRN1,RASGRF2,GHR,LIN7A,PPP2R2B,FIGN,MYRIP,SNAI2,DUSP1 |
| 2.783e-03 | -5.88 | Golgi apparatus part | cellular component | GO:0044431 | 936 | 114 | 18223 | 1724 |
PCSK1N,SCAMP1,LPCAT2,GALNT12,GALNT6,ATP8A1,XYLT1,MYO1B,RGS20,RNF24,CHAC1,FAM198B,MGAT5B,BCAN,SNX9,CHST10,SLC9A7,TLR3,SEC16B,RAB26,NBEA,TMED9,PROS1,COG3,CLVS2,RAB27B,GALNT18,RASGRP1,ATL1,CD55,GCNT2,ERGIC1,B3GALT1,WLS,TGFA,LRRK2,RNF125,CBY1,PXYLP1,RAB38,GPC6,ARHGAP21,GBP1,ATP7B,TNFRSF1A,B3GALT2,PAM,DSEL,HS3ST3B1,RAB30,RETREG1,HACE1,PCSK5,UST,HID1,SEC24D,BACE1,ATP9A,ST6GAL1,DHCR24,CLSTN2,GALNT13,CHSY1,GAS6,NDFIP2,GSAP,RAB11FIP5,GALNT1,GBGT1,ABCA5,MGAT1,FUT9,SREBF1,HS3ST5,LMAN2,FIG4,ST8SIA1,NCAM1,PCSK6,B4GALT6,NOS3,CHSY3,IL17RD,QSOX1,PODXL2,PLEKHA8,RAB6B,CYTH3,SYBU,MGAT4B,LITAF,GPSM1,SDC3,ST6GALNAC3,GALNT17,ARHGAP32,SNAP25,FNDC3A,B4GALNT3,GALNT14,GLCE,GALNT3,ICA1,SH3GL2,RND3,PMEPA1,ACER2,QPCTL,RAB31,PLD1,CERS1,MMP16,B4GALT7,ABCG1 |
| 2.795e-03 | -5.88 | Muscle contraction | REACTOME pathways | R-HSA-397014 | 204 | 32 | 10287 | 971 |
SCN5A,KCNIP3,SORBS1,PXN,CACNG3,FGF13,SCN8A,FGF12,RYR2,VIM,SORBS3,ITPR2,KCND3,ATP1B1,CACNB4,ASPH,KCNK15,KCNJ4,SCN1B,CACNB2,WWTR1,ACTA2,TRPC1,TMOD2,SCN2A,TPM1,NEB,ATP2B4,CACNA2D1,ATP2B1,SCN3A,ATP1A3 |
| 2.795e-03 | -5.88 | LIU_CMYB_TARGETS_UP | MSigDB lists | LIU_CMYB_TARGETS_UP | 157 | 27 | 17377 | 1707 |
SERINC5,ZNF395,MYO10,CRIM1,LITAF,BNIP3L,FHL2,DUSP9,ASS1,AK4,SATB2,PRKAR2B,ISYNA1,OVOL2,CA8,SLCO3A1,ISG20,PPM1E,ICA1,RPS6KA2,INSIG1,TACC2,LHX6,KCNS3,MARCH3,GSTM3,PCOLCE2 |
| 2.802e-03 | -5.88 | GO_INTRACELLULAR_VESICLE | MSigDB lists | GO_INTRACELLULAR_VESICLE | 1203 | 147 | 17377 | 1707 |
DOC2A,CACNG3,PRSS12,SYT12,ATP8A1,LDLR,VAMP8,SNX9,NCS1,PCDH7,RND2,HPS1,MARVELD2,ITGB3,RAB26,TMED9,PACSIN1,MYRIP,CPE,PDGFRB,LAMP3,TNK2,CD55,SLC3A2,ABCC4,WLS,TGFA,LRRK2,TRIM9,GPRC5B,ENTPD7,ATP7B,ALDOA,AHNAK2,PIK3C2B,INPP5F,NRP1,APBA2,PCSK5,SV2B,STXBP5L,FN1,SEC24D,SCN8A,ATP6V1E2,APBA1,MLC1,SPINK5,SPIRE1,SLC30A4,SREBF1,LRP6,GRIP1,CADPS2,MPDZ,DENND1C,STXBP1,CKAP4,GPR161,NOS3,SNX7,FGFR4,QSOX1,BDNF,DISC1,RHOQ,FASN,HIP1,RABAC1,ARRDC4,TMEM74,BAIAP2,TBC1D2,SH3GL2,FCHO2,SH3BP4,RAB31,PTPRN2,PLD1,FNBP1L,SFN,MME,DMXL2,PLA2G4A,PCSK1N,AMOTL1,SCAMP1,RNF144A,MSR1,RGS20,ADD2,CANX,NRXN1,STARD4,DAB2IP,PROS1,CLVS2,RAB27B,SYNGR3,TMEM67,GARS,FZD4,RAB38,RARRES2,FGFR1,GABARAPL1,SNCA,ARHGAP21,PAM,HGF,ATG5,SEPT5,CTTNBP2,STON2,MYO1D,LPAR2,PRSS16,GLIPR1L1,RUSC2,BACE1,GAS6,PKN1,RAB11FIP5,KCNJ4,TECPR1,EHD3,SGK3,MARCH3,MYO6,ESD,SYK,FES,VEGFC,SLC40A1,RAB3B,RAB6B,RAPGEF2,SYBU,PHACTR2,FNDC3A,TLR6,ICA1,SLC1A5,TBC1D4,KIF1B,OCLN,STOM |
| 2.807e-03 | -5.88 | positive regulation of cell motility | biological process | GO:2000147 | 506 | 68 | 17256 | 1658 |
AMOTL1,ACVR1,DOCK1,RHOD,ATP8A1,COL18A1,GATA3,NTRK3,PRKCA,SEMA6A,F3,TCAF2,ITGB3,DAB2IP,MET,DOCK8,SNAI2,PDGFRB,FER,GCNT2,PREX1,WNT11,RARRES2,CD40,DOCK5,FGFR1,IRS2,SMAD3,CXCL10,NCKAP1L,CCBE1,PLK2,APELA,ITGA2,LAMB1,HGF,SEMA3C,NRP1,LGALS3,BMPR2,FN1,ITGA6,GAS6,IGF1R,SEMA4F,GATA2,RRAS2,SPRY2,NOS3,VEGFC,PAK1,EPB41L5,RAPGEF2,RACK1,GPLD1,PTPRC,FGR,DOCK7,MYADM,RIPOR2,TERT,AKT3,CSF1,THBS4,XBP1,BMP4,SEMA3A,SHTN1 |
| 2.810e-03 | -5.87 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP | 188 | 31 | 17377 | 1707 |
PAK1,ST14,ST6GAL1,MGAT4B,PPFIBP2,CYP4V2,LHPP,DNER,ABHD4,GDPD5,SLCO3A1,IL18R1,FHOD3,BCL11A,EPB41L3,MYADM,KMO,GNB4,FAM107B,TSC22D1,BMP1,CDH17,RCN3,ACVR2A,GEM,PTPRE,SPRY2,GATM,PDGFRB,FES,B4GALT6 |
| 2.810e-03 | -5.87 | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP | MSigDB lists | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP | 188 | 31 | 17377 | 1707 |
ARHGAP26,PDLIM7,TTC39B,FBXO4,PTPN13,MPP1,DNAJC3,VAMP8,LRMP,LITAF,PHACTR2,BATF,IKZF2,SMAD3,CXCL10,ICA1,GRHL1,SH3RF1,PPFIBP1,TMEM86A,MPP2,SMTN,BCL6,SLC22A15,PCOLCE2,NRP1,RNF157,ZNF518B,TBC1D4,DOCK6,SNAI2 |
| 2.810e-03 | -5.87 | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_DN | MSigDB lists | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_UNSTIM_MACROPHAGE_DN | 188 | 31 | 17377 | 1707 |
B9D1,LONRF1,RIN2,TBKBP1,TCP11L2,DCC,RECK,GPR65,LRP4,MCTP2,WDFY4,RADIL,RAC3,NCS1,MKX,EBF1,GPR15,KCNMB4,MFSD2A,ABI3,KCNG1,TNFRSF1A,SGK1,ERCC5,TSPAN13,KLF9,SH3PXD2B,GEM,LRP12,ZNF385A,CEBPD |
| 2.810e-03 | -5.87 | GSE42021_TREG_VS_TCONV_PLN_DN | MSigDB lists | GSE42021_TREG_VS_TCONV_PLN_DN | 188 | 31 | 17377 | 1707 |
CREB3L2,TYRO3,GNG12,TUBA1A,ENO2,ZNF395,CAP2,PTPN6,VLDLR,MGAT4B,DEPTOR,ADD2,ROR1,RABAC1,PALLD,EML1,TMCO3,ABLIM1,IDI1,SLC7A11,GPRC5B,NACC2,P4HA2,AKT3,AHNAK2,TMOD2,MARCKS,DHCR7,PERP,IGSF3,CNTN1 |
| 2.810e-03 | -5.87 | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN | MSigDB lists | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN | 188 | 31 | 17377 | 1707 |
TRPM4,GPM6A,LGALS3,FN1,ITGA6,MGAT4B,TUBE1,COBLL1,KCTD12,LRRC49,GPLD1,HOMER3,ENTPD1,MYADM,EIF4EBP1,CSF1,DSG2,STC2,XBP1,FAM107B,INPP4B,ACVR2A,GSTM3,DLG2,DBP,PROS1,BMPR1A,NEB,RPS23,TPT1,RRAGD |
| 2.810e-03 | -5.87 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 188 | 31 | 17377 | 1707 |
PAK1,EIF4E3,ALDH2,NR4A1,ATP9A,PSTPIP2,YPEL2,LITAF,GTF2IRD1,RASL11B,VIM,CD7,FAM110B,TBC1D19,ISG20,CA2,KLF12,PLOD2,TACC2,MAP2,ENTPD7,GNB4,FAM168A,NCOA7,TSC22D1,PTPRS,ADCY6,EPHB6,PURG,RRAGD,PARP9 |
| 2.810e-03 | -5.87 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_DN | 188 | 31 | 17377 | 1707 |
WDR17,TTC39B,BMPR2,ACVR1C,GLIPR1L1,DSTN,ZCCHC24,SPATA13,ADAMTS6,ACVR2B,P2RY1,CD40,ARRDC4,TBC1D16,AHRR,ENTPD1,CAMK2N1,CD37,COL22A1,PTPRJ,MYADM,AADAT,PMEPA1,ABI3,BEND4,ST8SIA1,GEM,NRP1,MYRIP,B4GALT7,CYP1B1 |
| 2.812e-03 | -5.87 | Marcks (myristoylated alanine rich protein kinase C substrate) | protein interactions | 17118 | 7 | 4 | 17029 | 1718 |
PRKCA,PRKCB,PRKCD,HACE1 |
| 2.812e-03 | -5.87 | ZNF580 (zinc finger protein 580) | protein interactions | 51157 | 7 | 4 | 17029 | 1718 |
PAX9,SH3GL2,PPP2R3A,XBP1 |
| 2.812e-03 | -5.87 | NECAB3 (N-terminal EF-hand calcium binding protein 3) | protein interactions | 63941 | 7 | 4 | 17029 | 1718 |
NECAB2,NECAB1,APBA2,MYC |
| 2.828e-03 | -5.87 | TBK1.DF_UP | MSigDB lists | TBK1.DF_UP | 268 | 41 | 17377 | 1707 |
ACVR1,ENO2,RHOBTB1,GALNT12,RGS20,NUP62CL,SLCO3A1,PCLO,PPP2R3A,IGF1R,ZDHHC6,OPN3,PROS1,MAST4,SNX10,HSPA2,LRP12,IGSF3,RIN2,GCA,SLC37A1,PNP,TUBA1A,TGFA,CRIP2,C3orf52,FERMT2,FEZ1,ATF3,ATP10D,STEAP1,EML1,SNCA,BEX4,IQCK,ATPAF2,KIAA0355,PTK7,WWTR1,TUFT1,INPP5F |
| 2.829e-03 | -5.87 | Y_phosphatase | pfam domains | PF00102 | 38 | 10 | 17054 | 1666 |
PTPRC,PTPRJ,PTPRU,PTPRD,PTPN6,PTPN13,PTPN21,PTPRS,PTPRN2,PTPRE |
| 2.829e-03 | -5.87 | SAM_2 | pfam domains | PF07647 | 38 | 10 | 17054 | 1666 |
EPHA3,PPFIBP1,KAZN,PPFIA2,SAMD11,PPFIBP2,PPFIA4,EPHB6,LCP2,PPP1R9A |
| 2.840e-03 | -5.86 | GSE12963_UNINF_VS_ENV_AND_NEF_DEFICIENT_HIV1_INF_CD4_TCELL_DN | MSigDB lists | GSE12963_UNINF_VS_ENV_AND_NEF_DEFICIENT_HIV1_INF_CD4_TCELL_DN | 127 | 23 | 17377 | 1707 |
KLHL23,IPO5,PANK1,CCNG1,SPIRE1,SLC35F1,LGI2,CPNE2,PPM1E,HLF,MYADM,KLF12,KPNA3,PMAIP1,RAP2A,C1QL4,NBEA,MAPK13,SPRY4,THSD1,MBOAT2,PERP,FRMD5 |
| 2.840e-03 | -5.86 | GSE45365_NK_CELL_VS_BCELL_DN | MSigDB lists | GSE45365_NK_CELL_VS_BCELL_DN | 127 | 23 | 17377 | 1707 |
PLA2G4A,MXI1,PDK1,CELSR3,ACVR1C,CNTNAP3,STAT4,ATOX1,TMTC4,CALCRL,ST6GALNAC3,CHAC1,DDIT4,SCIN,SPATA9,CACHD1,VPS37D,WDR19,TMEM143,MARCH3,PDE4D,PLD5,PCSK5 |
| 2.844e-03 | -5.86 | NEDD4L (neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase) | protein interactions | 23327 | 191 | 32 | 17029 | 1718 |
TNK2,SCN5A,DYRK3,AMOTL1,APBB1,FGF12,EDEM3,LITAF,PRRG1,RASL11B,SCD,NPC2,ATP1B1,NHP2,ARRDC4,NDFIP2,SGK2,TNFRSF19,SNCA,SMAD3,KCNAB1,MAP2,AKT3,SGK3,SGK1,GRB10,BMPR1A,SMAD6,PRR16,MAP3K20,SFN,OCLN |
| 2.844e-03 | -5.86 | FCH | pfam domains | PF00611 | 21 | 7 | 17054 | 1666 |
FER,PACSIN1,FNBP1L,FCHO2,PSTPIP2,PACSIN3,SRGAP1 |
| 2.845e-03 | -5.86 | occluding junction | cellular component | GO:0070160 | 124 | 22 | 18223 | 1724 |
CGN,AMOTL1,BVES,PARD3B,RAPGEF2,CYTH3,TJP1,JAM3,MAGI3,PATJ,EPCAM,MPP7,MARVELD2,CLDN12,POF1B,LIN7A,MPDZ,YBX3,JAM2,MAGI2,NPHP1,OCLN |
| 2.850e-03 | -5.86 | TMEM255A (transmembrane protein 255A) | protein interactions | 55026 | 11 | 5 | 17029 | 1718 |
COLGALT2,GCA,ANKRD13D,UBASH3B,NEDD4 |
| 2.850e-03 | -5.86 | INHBB (inhibin subunit beta B) | protein interactions | 3625 | 11 | 5 | 17029 | 1718 |
ACVR2A,INHBC,ACVR2B,ACVR1,ACVR1C |
| 2.857e-03 | -5.86 | ZHENG_BOUND_BY_FOXP3 | MSigDB lists | ZHENG_BOUND_BY_FOXP3 | 461 | 64 | 17377 | 1707 |
TTC39B,GPR65,GATA3,COBLL1,TUBE1,ADAMTS6,STAT5B,ITPR2,GRK6,CACNB4,IKZF2,KBTBD11,SNX9,TBC1D30,STK24,CD53,BCL6,CPE,TMEM67,EXOC6B,RNF125,PRKCQ,PRKAR2B,SESN1,SNCA,SMAD3,ENPP1,ENPP6,INPP4B,RGS10,P4HA1,ZBTB20,NRP1,MLLT3,UST,BCL11B,LATS2,GRB14,ITGA6,ST6GAL1,UBASH3B,SCN8A,UBAC2,SELL,SATB1,PGAP1,PRRG4,ABLIM1,FAM107B,TOX,TSPAN13,ST8SIA1,VGLL4,RRAS2,ZFP36L2,ATP2B1,STAT4,ARID5B,RASA3,PRDM1,TLR6,PTPRC,ICA1,TBC1D4 |
| 2.861e-03 | -5.86 | skin-forearm-malignant_melanoma | COSMIC cancer mutations | skin-forearm-malignant_melanoma | 57 | 13 | 17385 | 1698 |
PTPRC,FER,PTPRJ,PTPRD,PTK7,PTPN13,PTPN21,PTPRS,PTPRN2,TNS1,EPHB1,MET,PTPRE |
| 2.866e-03 | -5.85 | GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT | MSigDB lists | GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DEVELOPMENT | 70 | 15 | 17377 | 1707 |
DISC1,ROBO2,SCN1B,GATA2,MAP2,DCC,RAPGEF2,LHX6,NRP1,EPHB1,SEMA3A,RAC3,SLIT2,FGFR1,TSKU |
| 2.875e-03 | -5.85 | GO_NEGATIVE_REGULATION_OF_LOCOMOTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LOCOMOTION | 252 | 39 | 17377 | 1707 |
NBL1,SEMA6B,ROBO2,RECK,ST6GAL1,GATA3,PKP2,ABHD6,PFN2,SEMA6A,STK24,SEMA4F,RAP2A,SRGAP1,DAB2IP,SLIT2,SEMA6C,NKX2-1,CYP1B1,IGFBP3,PHLDB2,MID2,EVL,ACVR1C,PTPRU,WNT11,SYNJ2BP,PLCB1,GSN,PTPRJ,NRG3,MCC,SEMA3C,NRP1,TPM1,PPARGC1A,TMEFF2,SEMA3A,MAGI2 |
| 2.876e-03 | -5.85 | REACTOME_HEMOSTASIS | MSigDB lists | REACTOME_HEMOSTASIS | 444 | 62 | 17377 | 1707 |
PLA2G4A,GNG12,PDE1B,FN1,DOCK1,GRB14,KIF5A,GATA3,SELL,HBE1,ITPR2,P2RY1,LCP2,DOCK3,PRKCA,DOCK2,F3,SLC7A11,GATA2,PDE10A,PRKCD,ITGB3,KCNMB3,PRKG1,PRKG2,PROS1,JAM2,SYK,RASGRP1,PRKACB,DOCK8,NOS3,VEGFC,VAV3,HBG2,SLC3A2,ABCC4,PTPN6,RAPGEF4,PRKAR2B,PRKCQ,ATP1B1,F12,ZFPM2,GUCY1A2,DOCK5,JAM3,GNAI1,DAGLA,FGR,KCNMB4,PRKCB,PRCP,AKT3,GNB4,ALDOA,ITGA2,SLC7A5,HGF,TRPC3,DOCK6,DOCK9 |
| 2.880e-03 | -5.85 | GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | MSigDB lists | GO_CENTRAL_NERVOUS_SYSTEM_NEURON_DIFFERENTIATION | 165 | 28 | 17377 | 1707 |
BCL11B,DISC1,ROBO2,DCC,RAPGEF2,SATB2,EPHB1,NRXN1,GDPD5,CHD5,RAC3,CBLN1,FGFR1,TSKU,NKX6-1,EOMES,SCN1B,MAP2,GATA2,LHX6,LRP6,DLX2,DYNC2H1,NRP1,SEMA3A,SLIT2,NKX2-1,FZD1 |
| 2.880e-03 | -5.85 | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 165 | 28 | 17377 | 1707 |
MOCOS,ANTXR2,PNP,PTPRU,PTPN13,ZCCHC24,CRIP2,MGAT4B,DHCR24,LRRC49,MFSD6,ASPH,MCU,CEBPB,BAG3,ICA1,IDI1,KLF12,AKAP7,PCBP4,STARD4,MPPED2,LAPTM4B,SGK1,PROS1,STXBP1,ATP2B4,HMGCR |
| 2.880e-03 | -5.85 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | MSigDB lists | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | 44 | 11 | 17377 | 1707 |
RGS17,GNG12,PRKCB,GNB4,PRKCD,RGS20,ADCY1,ADCY6,PRKCQ,PRKCA,GNAI1 |
| 2.884e-03 | -5.85 | cellular localization | biological process | GO:0051641 | 2247 | 253 | 17256 | 1658 |
DOC2A,EXPH5,THOC5,CACNG3,UGT8,FGF13,GRIK2,SYT12,KIF5A,LDLR,VAMP8,NPM1,ITPR2,SYT14,SNX9,NUP62CL,TRPS1,TUBB4A,ADPRHL1,SEC16B,PMAIP1,PPFIA2,RAP2A,RAB26,NDUFB8,TBC1D32,LIN7A,TMED9,CTTN,COG3,TLN2,PACSIN1,MYRIP,CPE,RASGRP1,TBC1D8,DBN1,GDAP1,ITGB7,CD55,KCNIP3,ERGIC1,WLS,ANK2,EXOC6B,TGFA,ATOX1,JPH1,LRRK2,DNAJC6,LRMP,FEZ1,PRKAR2B,ZDHHC14,TRIM9,GSN,INSIG1,WIPF3,ATP7B,TNFRSF1A,NRP1,MAGI2,TC2N,RRAGD,CHMP4C,PRKAA2,CELSR1,HID1,SEC24D,TBC1D1,BVES,STXBP6,OPHN1,GPSM2,APBA1,DYNC1I1,BBS9,TTC30B,PGAP1,RPL13A,GRPEL2,SPIRE1,CACNB2,RPS11,LRP6,LMAN2,CADPS2,DENND1C,FAM155A,STXBP1,RPS23,ZNF385A,RIMS2,BOD1,RPL26,MID2,MYO10,TBC1D8B,PLEKHA8,DCHS1,PPFIA4,RYR2,HIP1,STRADB,OBSCN,TTC30A,PEX5L,NPC2,SNAP25,CLN5,HERPUD1,SPATA7,TBC1D2,VPS37D,SH3GL2,RPL28,FCHO2,WDR19,SH3BP4,RAB31,HK2,DYNC2LI1,PTPRN2,LAPTM4B,FNBP1L,CDH2,TESC,SIX2,CREB3L2,PRKN,DNM3,ID1,TCTN2,AKAP5,TMSB15A,RHOD,PLXNA2,PKP2,CANX,NRXN1,DENND3,PIBF1,PCLO,TBC1D30,DOCK2,ZFYVE9,SCIN,EPB41L3,UNC13B,PDZD8,REEP1,STARD4,ZDHHC6,BCL6,ZDHHC23,MAP7,RTKN2,PROS1,FAM155B,RAB27B,SNX10,KCNB2,RPS13,DPP10,TMEM67,TUBA1A,NOP53,PTPRU,NLGN4X,WNT11,ATP1B1,PYGO1,RAB38,SYNJ2BP,TBC1D16,SNCA,RANBP2,IFT81,ARHGAP21,KPNA3,BACH2,GBP1,SEPT5,MID1,STON2,RAB30,THOC3,RPS20,TNIK,MYO1D,SLC6A9,TSPAN15,CLBA1,IPO5,LRP4,CMTM8,UBAC2,ARL2,KIF5C,GAS6,P2RY1,TSPAN17,NEDD4,ARHGAP44,RPL34,RAB11FIP5,MAP1A,BHLHA15,EHD3,PRKG2,SH3PXD2B,DYNC2H1,MYO6,TBC1D9,SEPT3,SPRY2,B9D1,RAB3B,MSX1,RAB6B,RAPGEF2,RPL21,SYBU,ZDHHC15,FERMT2,PRICKLE1,RASA3,MEI1,SKAP1,HOMER3,MAP1B,RERE,PTPRC,DOCK7,RPL12,MYADM,NACC2,TERT,GRIN2D,DLG2,RPL4,HK1,RPS12,BMP4,GEM,TBC1D4,KIF1B,NPHP1,DDIT3,ATP2B4,CACNA2D1,ABCG1,SNPH |
| 2.884e-03 | -5.85 | PTPase_domain | interpro domains | IPR000242 | 38 | 10 | 18492 | 1811 |
PTPRC,PTPRJ,PTPRU,PTPRD,PTPN6,PTPN13,PTPN21,PTPRS,PTPRN2,PTPRE |
| 2.887e-03 | -5.85 | DAG/PE-bd | interpro domains | IPR020454 | 21 | 7 | 18492 | 1811 |
CHN1,PRKCQ,CHN2,PRKCA,PRKCB,PRKCD,RASGRP1 |
| 2.888e-03 | -5.85 | transmembrane receptor protein phosphatase activity | molecular function | GO:0019198 | 16 | 6 | 17224 | 1680 |
PTPRN2,PTPRC,PTPRU,PTPRE,PTPRD,PTPN6 |
| 2.888e-03 | -5.85 | protein kinase C activity | molecular function | GO:0004697 | 16 | 6 | 17224 | 1680 |
PRKCQ,PRKCA,PKN1,PRKCB,PKN3,PRKCD |
| 2.888e-03 | -5.85 | transmembrane receptor protein tyrosine phosphatase activity | molecular function | GO:0005001 | 16 | 6 | 17224 | 1680 |
PTPRN2,PTPRC,PTPRU,PTPRE,PTPRD,PTPN6 |
| 2.890e-03 | -5.85 | GO_ENDOCARDIAL_CUSHION_DEVELOPMENT | MSigDB lists | GO_ENDOCARDIAL_CUSHION_DEVELOPMENT | 32 | 9 | 17377 | 1707 |
MSX1,ACVR1,HEYL,DCHS1,BMP4,BMPR1A,SNAI2,NEDD4,HEY1 |
| 2.890e-03 | -5.85 | GO_HEART_VALVE_DEVELOPMENT | MSigDB lists | GO_HEART_VALVE_DEVELOPMENT | 32 | 9 | 17377 | 1707 |
ACVR1,HEYL,DCHS1,GATA3,PRDM1,SMAD6,SHOX2,HEY1,MEF2C |
| 2.890e-03 | -5.85 | HU_GENOTOXIC_DAMAGE_24HR | MSigDB lists | HU_GENOTOXIC_DAMAGE_24HR | 32 | 9 | 17377 | 1707 |
BAG3,ATF4,EEF2,EIF4EBP1,SLC7A5,DDR1,CD7,HERPUD1,BATF3 |
| 2.890e-03 | -5.85 | GO_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT | MSigDB lists | GO_REGULATION_OF_ACTIN_FILAMENT_BASED_MOVEMENT | 32 | 9 | 17377 | 1707 |
TRPM4,SCN5A,ANK2,DSG2,RYR2,PKP2,PDE4D,DSP,NOS1AP |
| 2.893e-03 | -5.85 | GO_AXON_PART | MSigDB lists | GO_AXON_PART | 212 | 34 | 17377 | 1707 |
MYO1D,ROBO2,PRSS12,GRIK2,SCN8A,APBB1,OPHN1,NRXN1,KCNC4,PFN2,TUBB4A,EPB41L3,UNC13B,KCNAB1,SCN1B,FLRT3,DAB2IP,MARCKS,PACSIN1,SCN2A,STXBP1,CHRM3,GPM6A,KCNIP3,KCNQ3,LRRK2,SNCA,DAGLA,ITGA2,PTPRN2,DLG2,SEPT5,KIF1B,COBL |
| 2.901e-03 | -5.84 | V$P53_DECAMER_Q2 | MSigDB lists | V$P53_DECAMER_Q2 | 236 | 37 | 17377 | 1707 |
BCL11B,MXI1,DYRK3,ANKRD13B,SLC6A9,BMPR2,HEBP1,BLVRB,FHDC1,OTX1,NTRK3,GRK6,SLC1A3,SLCO3A1,CHD5,ZNF362,HMGCS1,DNAH6,CACNB2,TSC22D1,DAB2IP,ERRFI1,TSHR,ETV1,TBC1D8,PXN,MSTN,TDRD3,NFE2L1,CLN5,SLC7A1,NCAM2,NXPH4,DLG2,LRRK1,TNFSF4,DOCK9 |
| 2.904e-03 | -5.84 | GO_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_PROTEIN_TYROSINE_PHOSPHATASE_ACTIVITY | 98 | 19 | 17377 | 1707 |
SSH3,DUSP8,PTPRU,PTPRD,PTPN13,UBASH3B,PTPN6,DNAJC6,PTPN21,DUSP9,EYA4,PTPRC,PTPRJ,CDC14B,DUSP19,PTPRN2,PTPRS,PTPRE,DUSP1 |
| 2.904e-03 | -5.84 | V$CDP_02 | MSigDB lists | V$CDP_02 | 98 | 19 | 17377 | 1707 |
EPHA3,PHACTR3,GPM6A,SLC6A9,SLITRK2,HNF4G,OTX1,GTF2IRD1,SLC1A3,IKZF2,SEMA6A,SP8,ATXN7L1,GNAO1,PCGF2,ACVR2A,MARCKS,KIF1B,MEF2C |
| 2.915e-03 | -5.84 | telencephalon cell migration | biological process | GO:0022029 | 58 | 13 | 17256 | 1658 |
NRG3,FGF13,LHX6,LAMB1,LRRK2,EFHC1,DAB2IP,NRP1,FOXG1,SEMA3A,SLIT2,POU3F3,NKX2-1 |
| 2.916e-03 | -5.84 | sequence-specific double-stranded DNA binding | molecular function | GO:1990837 | 774 | 99 | 17224 | 1680 |
CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,ZNF93,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,HEY1,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,KDM5B,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 |
| 2.920e-03 | -5.84 | DAGPEDOMAIN | prints domains | PR00008 | 21 | 7 | 4652 | 458 |
CHN1,PRKCQ,CHN2,PRKCA,PRKCB,PRKCD,RASGRP1 |
| 2.937e-03 | -5.83 | CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP | MSigDB lists | CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP | 21 | 7 | 17377 | 1707 |
STAT5B,CD55,ACSL1,INSIG1,HSPA2,MYC,CTH |
| 2.937e-03 | -5.83 | MODULE_295 | MSigDB lists | MODULE_295 | 21 | 7 | 17377 | 1707 |
CBS,CA2,EHHADH,ENO2,UROS,CA8,ACO1 |
| 2.937e-03 | -5.83 | VALK_AML_WITH_EVI1 | MSigDB lists | VALK_AML_WITH_EVI1 | 21 | 7 | 17377 | 1707 |
MN1,DMXL2,SORBS3,PIK3C2B,NPDC1,CRIM1,GNAI1 |
| 2.937e-03 | -5.83 | chr8q23 | MSigDB lists | chr8q23 | 21 | 7 | 17377 | 1707 |
ZFPM2,COLEC10,SNTB1,COL14A1,SYBU,TMEM74,TRPS1 |
| 2.937e-03 | -5.83 | WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP | 21 | 7 | 17377 | 1707 |
FGFR4,SQLE,MVK,IL32,PMAIP1,SLC2A6,PCSK6 |
| 2.937e-03 | -5.83 | GO_MALE_GENITALIA_DEVELOPMENT | MSigDB lists | GO_MALE_GENITALIA_DEVELOPMENT | 21 | 7 | 17377 | 1707 |
SYCP2,HOXD13,TEX15,LGR4,BMP6,GJB2,DHCR24 |
| 2.937e-03 | -5.83 | GO_CELL_CELL_SIGNALING_INVOLVED_IN_CARDIAC_CONDUCTION | MSigDB lists | GO_CELL_CELL_SIGNALING_INVOLVED_IN_CARDIAC_CONDUCTION | 21 | 7 | 17377 | 1707 |
PKP2,RYR2,SCN5A,SCN1B,CACNB2,ANK2,GJC1 |
| 2.942e-03 | -5.83 | regulation of osteoblast differentiation | biological process | GO:0045667 | 115 | 21 | 17256 | 1658 |
PDLIM7,TRPM4,ID1,RUNX2,ACVR1,BMPR2,ZHX3,CEBPA,ACVR2B,BMP6,SKI,SMAD3,CEBPB,ID3,ACVR2A,HGF,BMPR1A,BMP4,SNAI2,GLI1,MEF2C |
| 2.950e-03 | -5.83 | Guanylate_kinase_CS | interpro domains | IPR020590 | 16 | 6 | 18492 | 1811 |
DLG2,MPP7,MAGI2,MPP1,MAGI3,MPP2 |
| 2.950e-03 | -5.83 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | 173 | 29 | 17377 | 1707 |
MAN2B2,SERINC5,EVL,RUNX2,BMPR2,PNRC1,UBASH3B,APBB1,CYP4V2,PREX1,NFIA,TTYH2,TTC22,ABAT,NPC2,RPL34,DYRK1B,MSC,CD37,IKZF3,KLF12,HPS1,CNNM2,ACVR2A,DHRS12,ZBTB20,NIPAL2,DIRC2,DOCK9 |
| 2.961e-03 | -5.82 | small molecule metabolic process | biological process | GO:0044281 | 1803 | 207 | 17256 | 1658 |
NMNAT3,MVK,ACSL1,ADAL,PDE1B,AASS,LDLR,UGDH,ASS1,STAT5B,CEBPA,ABAT,BCAN,CA8,AARS,QPRT,CYP51A1,TYMP,AADAT,FAAH2,TMEM86A,NDUFB8,PLTP,ENO1,GLDC,CYP1B1,SESN2,ATF4,CEMIP2,ALDH1L2,LRRK2,GDPD1,NFE2L1,HACD1,PRKAR2B,ABCC2,CA13,PYCR1,AK1,ENPP1,INSIG1,ENTPD7,ALDOA,BDH2,TNFRSF1A,DSEL,PPARGC1A,SPOCK3,CRYL1,PRKAA2,UST,CARS,GPT2,MOCOS,INPPL1,ALOX5AP,EHHADH,OTOGL,CYP2J2,ST6GAL1,OLAH,DHCR24,ELOVL7,RIMKLA,CYP4V2,SCD,CHSY1,ISYNA1,SLC1A3,PHGDH,ADSSL1,PRTFDC1,CA2,MSMO1,PDE10A,SREBF1,ADCY6,SLC16A9,MOXD1,NOS3,HMGCR,CHSY3,FADS1,ATP5IF1,PODXL2,RHOQ,B3GLCT,PNP,SLC27A2,MGST3,VLDLR,FASN,PDE8A,AIG1,NPC2,LHPP,PLCB1,AMDHD1,GLCE,MAPKAPK2,DAGLA,RIMKLB,GSTO2,MPP2,HK2,SQLE,DHCR7,OSBPL6,PANK3,MME,AMPD1,ACSM3,PLA2G4A,NUDT10,ELOVL4,IL15,XYLT1,SLC7A2,LPIN3,NUDT12,SLC19A2,CYP26A1,IDI1,ERG28,ASNS,ERO1B,KMO,ALDOC,ALDH1L1,FHIT,PDE4D,MDH1B,GATM,CTH,VNN2,GAPDH,GARS,UROS,PDK1,PFKFB2,MVD,PANK1,ACO1,ADCY1,GSTO1,ATF3,ATP1B1,MAGI3,FGFR1,SNCA,WARS,TPK1,IRS2,ENTPD1,TDO2,PEMT,INPP4B,PAM,P4HA1,HPGD,HGF,CYP2U1,PSPH,MAN2B2,SERINC5,ENO2,GCAT,CBS,INPP1,HMGCS1,SOAT2,FUT9,MGAT1,GHR,PHYKPL,PCK2,ESD,SYK,SMPDL3A,PARP9,B4GALT6,PFKFB4,GSTM2,ALDH2,HYKK,MPP1,ELOVL3,OGDHL,AK4,MARS,GUCY1A2,LRAT,LEPR,DDAH1,PLOD2,ACER2,SRD5A3,XBP1,OSBPL5,SLC7A5,PGM2L1,DLG2,HK1,CMPK2,PTGES,ABCG1,NUDT17 |
| 2.963e-03 | -5.82 | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | 150 | 26 | 17377 | 1707 |
RIN2,RHOBTB1,ST14,RNF144A,PTPN13,GJB2,BIK,PRDM1,FAM81A,IL18R1,NEO1,GABARAPL1,EPCAM,CAMK2N1,ENTPD1,PTPRJ,TGFBR3,AKAP7,GPR160,ALDOC,EHD3,MATN2,ST8SIA1,POU2F2,RAPGEF5,FRMD5 |
| 2.974e-03 | -5.82 | EGF_CA | smart domains | SM00179 | 120 | 24 | 9493 | 1056 |
CELSR1,CELSR3,LRP4,VLDLR,LDLR,C1R,F12,GAS6,DNER,HMCN1,HEG1,EFEMP1,NELL2,FAT4,FBN1,FAT1,CCBE1,THBS4,MATN2,BMP1,EGFL7,PROS1,SLIT2,TLL2 |
| 2.992e-03 | -5.81 | axis elongation | biological process | GO:0003401 | 27 | 8 | 17256 | 1658 |
PTK7,LRP6,YAP1,HOXD13,WNT11,BMP4,MAGI2,SPRY2 |
| 2.992e-03 | -5.81 | regulation of B cell differentiation | biological process | GO:0045577 | 27 | 8 | 17256 | 1658 |
IKZF3,NCKAP1L,PTPN6,XBP1,STAT5B,PRDM1,ZFP36L2,SYK |
| 2.993e-03 | -5.81 | GINM1 (glycoprotein integral membrane 1) | protein interactions | 116254 | 62 | 14 | 17029 | 1718 |
GALNT1,MGAT1,GALNT12,PLEKHA5,CTSV,LDLR,ACVR2A,PTPRS,ACVR2B,BMPR1A,NRP1,FGFR1,B4GALT7,GLCE |
| 2.995e-03 | -5.81 | GO_DENDRITE_CYTOPLASM | MSigDB lists | GO_DENDRITE_CYTOPLASM | 16 | 6 | 17377 | 1707 |
KCNAB1,CANX,GRIK2,WLS,LRRK2,GABARAPL1 |
| 2.995e-03 | -5.81 | GO_PROTEIN_KINASE_C_ACTIVITY | MSigDB lists | GO_PROTEIN_KINASE_C_ACTIVITY | 16 | 6 | 17377 | 1707 |
PRKCQ,PKN1,PRKCA,PKN3,PRKCB,PRKCD |
| 2.995e-03 | -5.81 | KANG_FLUOROURACIL_RESISTANCE_DN | MSigDB lists | KANG_FLUOROURACIL_RESISTANCE_DN | 16 | 6 | 17377 | 1707 |
OPLAH,PCK2,BACE2,LDLR,DDIT4,SLC43A1 |
| 2.995e-03 | -5.81 | GO_RETINA_VASCULATURE_DEVELOPMENT_IN_CAMERA_TYPE_EYE | MSigDB lists | GO_RETINA_VASCULATURE_DEVELOPMENT_IN_CAMERA_TYPE_EYE | 16 | 6 | 17377 | 1707 |
ACVR2B,NRP1,BMPR2,FZD4,PDGFRB,CYP1B1 |
| 2.995e-03 | -5.81 | GO_PARAXIAL_MESODERM_DEVELOPMENT | MSigDB lists | GO_PARAXIAL_MESODERM_DEVELOPMENT | 16 | 6 | 17377 | 1707 |
SMAD3,YAP1,EPB41L5,WNT11,BMPR1A,FGFR1 |
| 2.995e-03 | -5.81 | KEGG_STEROID_BIOSYNTHESIS | MSigDB lists | KEGG_STEROID_BIOSYNTHESIS | 16 | 6 | 17377 | 1707 |
CYP51A1,SQLE,SOAT2,MSMO1,DHCR7,DHCR24 |
| 2.995e-03 | -5.81 | FARMER_BREAST_CANCER_CLUSTER_6 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_6 | 16 | 6 | 17377 | 1707 |
GATA3,TSPAN13,TBC1D9,TTC39A,FOXA1,XBP1 |
| 2.998e-03 | -5.81 | PON2 (paraoxonase 2) | protein interactions | 5445 | 82 | 17 | 17029 | 1718 |
UST,ENPP1,UGT8,LMLN,RNF170,ITGA6,C1QL4,NXPH4,ST6GALNAC3,RNF130,AMIGO1,CHSY1,MOXD1,PGAP1,CACNA2D1,CHST10,STOM |
| 3.008e-03 | -5.81 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN | 181 | 30 | 17377 | 1707 |
BCL7A,SERINC5,FLVCR2,CHCHD7,AKAP5,LRRC8B,TES,HOMER2,PLXNA2,VIM,ANKRD18A,ARRDC4,PALLD,NDFIP2,RBM11,CACNB4,FAM110B,BMP6,BATF3,TIFA,WFS1,PPFIBP1,P4HA2,MAOA,FAR2,PTPRE,RAB30,CES3,RRAGD,TBC1D8 |
| 3.008e-03 | -5.81 | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | 181 | 30 | 17377 | 1707 |
VNN2,RHOQ,ACSL1,SH3BP2,SETBP1,CEBPA,PRKAR2B,WDFY4,TMEM170B,MLC1,TLR6,RTN1,CEBPB,GBGT1,EPB41L3,TMEM154,TM9SF2,PRCP,PRKCD,OSBPL5,KIAA0513,TNFSF15,SLC22A15,NCEH1,PTPRE,TLR4,FMNL2,ZNF385A,TBC1D8,B4GALT6 |
| 3.008e-03 | -5.81 | GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP | MSigDB lists | GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP | 181 | 30 | 17377 | 1707 |
EXPH5,MTG1,TNK2,MXI1,AASS,FAM131C,EFHC2,SMARCD3,AK4,CHRNA6,HBE1,DACH2,LRAT,CTNNA2,TBC1D2,CAMK2N1,PELI2,GSTM3,COL19A1,DAB2IP,PDE4D,SLCO4C1,GFI1,ESD,NTNG1,SLC16A10,FILIP1,NOS3,C3orf67,FZD1 |
| 3.008e-03 | -5.81 | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_UP | 181 | 30 | 17377 | 1707 |
FADS1,QSOX1,BCL7A,RASAL2,TUBA1A,TGFA,DHCR24,LITAF,FASN,SCD,GAS6,CD40,SEL1L3,FAM110B,FAM162A,HOPX,BATF3,MCOLN2,IGF1R,MSMO1,ABCA5,P4HA2,STARD4,BDH2,SQLE,MAOA,MAST4,DIRC2,LAMP3,ABCG1 |
| 3.008e-03 | -5.81 | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN | MSigDB lists | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN | 181 | 30 | 17377 | 1707 |
ARHGAP26,DBN1,BCL7A,VAV3,RHOQ,SH2D2A,CRIM1,GPR65,ATP8A1,SYBU,MCTP2,LITAF,FEZ1,HIP1,CHSY1,ROR1,PALLD,CHST10,GALNT3,CAMK2N1,GALNT1,TLR3,TGFBR3,FAT4,CCNA1,C1orf21,MYO6,SYNGR3,RRAS2,GFI1 |
| 3.008e-03 | -5.81 | GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_UP | 181 | 30 | 17377 | 1707 |
ITGB7,SCN5A,SLC27A2,MYO10,ANK2,LRP4,PHACTR2,PDE8A,PGAP1,NEDD4,PLEKHB1,ISG20,RAB11FIP5,MSC,ID3,NCAM2,CDC14B,WFS1,ALDOC,NDUFB8,PAM,ADCY6,IPCEF1,POU2F2,ATG5,VWA5A,MOXD1,MAPK10,FOXA1,GLI1 |
| 3.008e-03 | -5.81 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | 181 | 30 | 17377 | 1707 |
RPS20,BCL7A,LPAR2,CD55,PXN,TES,SPATA6,PPFIBP2,ATF7IP2,RASA3,STAT5B,SYNJ2BP,ROR1,PLEKHA1,PRKCA,RNF44,SLC46A3,BEX4,PAIP2B,MAP2K6,TSC22D1,SVIL,KLF9,DBP,DENND1C,TBC1D4,ZFP36L2,SP140L,SNPH,DUSP1 |
| 3.009e-03 | -5.81 | GO_NUCLEOTIDE_PHOSPHORYLATION | MSigDB lists | GO_NUCLEOTIDE_PHOSPHORYLATION | 57 | 13 | 17377 | 1707 |
PFKFB4,AK1,GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,OGDHL,HK2,AK4,HK1,CMPK2,ENO1 |
| 3.009e-03 | -5.81 | chr4q31 | MSigDB lists | chr4q31 | 57 | 13 | 17377 | 1707 |
ZNF827,RNF150,TMEM154,TRIM2,IL15,TDO2,SLC10A7,TIGD4,FHDC1,INPP4B,TBC1D9,NR3C2,LRAT |
| 3.009e-03 | -5.81 | chr3q26 | MSigDB lists | chr3q26 | 57 | 13 | 17377 | 1707 |
TNIK,EHHADH,KCNAB1,BCHE,GPR160,KCNMB3,SERPINI1,ZBBX,PLD1,NCEH1,NAALADL2,MECOM,LAMP3 |
| 3.028e-03 | -5.80 | NABA_CORE_MATRISOME | MSigDB lists | NABA_CORE_MATRISOME | 269 | 41 | 17377 | 1707 |
COL9A3,FN1,IGFBP6,LAMC3,COL18A1,COL4A5,CHADL,GAS6,BCAN,COL14A1,HMCN1,COL27A1,LGI2,EFEMP1,COL22A1,NELL2,ABI3BP,COL25A1,FRAS1,VWDE,COL19A1,PCOLCE2,VWA5A,COL9A2,SLIT2,NTNG1,IGFBP3,COL6A2,COL4A3,CRIM1,WISP3,THSD4,COL4A4,TSKU,FBN1,THBS4,MATN2,EMILIN2,LAMB1,SPOCK3,CRISPLD1 |
| 3.034e-03 | -5.80 | inositol lipid-mediated signaling | biological process | GO:0048017 | 65 | 14 | 17256 | 1658 |
TYRO3,IRS2,GSN,IGF1R,GATA3,INPP5F,PIK3C2B,PLD1,PLEKHA1,CA8,FGFR1,NCS1,PDGFRB,GAB2 |
| 3.041e-03 | -5.80 | neurotransmitter metabolic process | biological process | GO:0042133 | 86 | 17 | 17256 | 1658 |
DAGLA,RNF180,PDE1B,BCHE,GCAT,ENPP6,MAOA,BTBD9,SLC1A3,ABAT,SLC7A2,MOXD1,PHGDH,TLR6,NOS3,CYP1B1,GLDC |
| 3.041e-03 | -5.80 | response to vitamin | biological process | GO:0033273 | 86 | 17 | 17256 | 1658 |
GDAP1,IL15,GAS6,CD40,LRAT,MGMT,CYP26A1,CXCL10,GSN,HMGCS1,ZNF354A,EEF2,BCHE,PEMT,ITGA2,STC2,ATP2B1 |
| 3.043e-03 | -5.79 | mevalonate pathway | BIOCYC pathways | HUMAN_PWY-922 | 10 | 5 | 902 | 105 |
HMGCS1,IDI1,MVK,MVD,HMGCR |
| 3.043e-03 | -5.79 | mevalonate pathway I | BIOCYC pathways | META_PWY-922 | 10 | 5 | 902 | 105 |
HMGCS1,IDI1,MVK,MVD,HMGCR |
| 3.052e-03 | -5.79 | Tmod3 (tropomodulin 3) | protein interactions | 50875 | 89 | 18 | 17029 | 1718 |
DBN1,PHLDB2,MYO1B,PACSIN3,ABLIM1,ARHGAP21,GSN,GNAO1,DSG2,GAS2L3,RAI14,SVIL,TPM1,MYO6,RRAS2,COBL,STON2,HACE1 |
| 3.053e-03 | -5.79 | GSE17721_LPS_VS_POLYIC_6H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDC_DN | 189 | 31 | 17377 | 1707 |
CREB3L2,EVL,SLC37A1,PNRC1,ITGA6,LRMP,BNIP3L,SYNJ2BP,COTL1,INTS6,DOCK5,ASPH,SCIN,GNAI1,FGR,RPL28,MYC,PLXDC2,ALDOA,EEPD1,SLCO5A1,SGK1,LMAN2,RNF130,TMEM37,ATG5,PCK2,TMEM56,STOM,MEF2C,ABCG1 |
| 3.053e-03 | -5.79 | GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_MEMORY_VS_CD21HIGH_TRANSITIONAL_BCELL_UP | 189 | 31 | 17377 | 1707 |
TRPM4,MID2,TMEM63C,RIN2,NBL1,TRIM2,RASAL2,GRB14,ARHGAP22,OTX1,MSRB3,STAT5B,ITPR2,MGAT5B,FAM81A,DOCK3,SNX9,GDPD5,MGMT,TRIM9,EPCAM,GSN,SLC7A11,PRCP,CNKSR3,FLRT3,INPP5F,PCK2,NRP1,RCAN3,NEB |
| 3.053e-03 | -5.79 | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_DN | MSigDB lists | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_DN | 189 | 31 | 17377 | 1707 |
IL17RD,GNG12,GARS,ACSL1,MYO10,JDP2,LDLR,CHUK,PHGDH,TLR6,SLCO3A1,CA13,GAS1,HOPX,MAPKAPK2,TTC1,CXCL10,GBGT1,MSC,FGR,ASNS,SLC7A11,RND3,RBPMS2,ZDHHC6,ERN1,TFAP2A,TSC22D1,TNFSF4,SYK,PARP9 |
| 3.053e-03 | -5.79 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP | 189 | 31 | 17377 | 1707 |
FADS1,QSOX1,BCL7A,FARP1,FN1,RHOBTB1,TGFA,BLVRB,PPFIBP2,PLXNA2,RNF125,TDRKH,PEX5L,NPC2,GAS6,RAB38,QPRT,BCL11A,CYP51A1,BEX4,CHN1,GSN,DACT1,MCC,SQLE,MAOA,SPRY4,FIG4,GATM,SFN,GAB2 |
| 3.053e-03 | -5.79 | GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | 189 | 31 | 17377 | 1707 |
MOB1B,ITGB7,DYRK3,LANCL3,TUBA1A,ABCC4,RNF145,RNF144A,UBASH3B,BACE1,GABRG2,FAM117B,CTBP2,CHSY1,ARRDC4,CD7,TEX9,BBS9,PGAP1,METAP1D,RANBP2,GPR160,MATN2,FAM107B,TSC22D1,RGS10,ZBTB20,MORN2,MARCKS,DISP2,APBA2 |
| 3.053e-03 | -5.79 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP | 189 | 31 | 17377 | 1707 |
MICAL2,ARAP2,SH3BP2,FLVCR2,SH2D2A,MVD,GATA3,HIP1,PHACTR2,TTC22,STAT5B,SFXN3,SLCO3A1,GPR19,SPIRE1,GABARAPL1,MAPKAPK2,CAMK2N1,IDI1,EOMES,FCHO2,PMAIP1,GNAO1,P4HA2,C1orf21,NCOA7,TOX,ST8SIA1,BMPR1A,GFI1,ATP2B4 |
| 3.053e-03 | -5.79 | GSE3982_MAC_VS_BCELL_UP | MSigDB lists | GSE3982_MAC_VS_BCELL_UP | 189 | 31 | 17377 | 1707 |
MICAL2,GCNT2,RASAL2,SKAP2,MYO10,MPP1,ATP9A,PTPN13,MLF1,EXOC6B,ACO1,AK4,PHACTR2,DOCK3,PPP2R3A,QPRT,GABARAPL1,BEX4,TMEM53,CXCL10,CHN2,P4HA2,WWTR1,BCL6,KCNS3,BMP1,IPCEF1,TLN2,MYO6,TLR4,LPP |
| 3.053e-03 | -5.79 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN | 189 | 31 | 17377 | 1707 |
AVPI1,ALOX5AP,PNP,SEC24D,ITPRIP,TES,UBASH3B,WLS,MVD,AGPAT4,LITAF,PSD3,VIM,PRDM1,NPC2,NHP2,BAIAP2,CYP51A1,EPCAM,SLC7A11,HPSE,STARD4,RAI14,RAB31,ATRNL1,ALG11,DSEL,TMED9,MED7,VWA5A,TBC1D9 |
| 3.060e-03 | -5.79 | KSR1 (kinase suppressor of ras 1) | protein interactions | 8844 | 103 | 20 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,TBC1D1,PTPN13,PLEKHA5,CBY1,LPIN3,SKAP1,FAM110B,BAIAP2,NAV1,RALGPS2,MAP3K21,SH3BP4,TANC2,OSBPL6,KIF1B,LARP1,GAB2 |
| 3.081e-03 | -5.78 | ATP generation from ADP | biological process | GO:0006757 | 39 | 10 | 17256 | 1658 |
GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,OGDHL,HK2,PGM2L1,HK1,ENO1 |
| 3.081e-03 | -5.78 | cellular response to epidermal growth factor stimulus | biological process | GO:0071364 | 39 | 10 | 17256 | 1658 |
ID1,PDE8A,MARS,STAT5B,GAREM1,DAB2IP,ERRFI1,ZFP36L2,BAIAP2,SNAI2 |
| 3.081e-03 | -5.78 | neutral amino acid transport | biological process | GO:0015804 | 39 | 10 | 17256 | 1658 |
SERINC5,SLC3A2,SLC6A9,SLC36A1,SERINC2,SLC7A5,SLC36A4,SLC6A15,SLC1A5,SLC43A1 |
| 3.083e-03 | -5.78 | regulation of muscle system process | biological process | GO:0090257 | 242 | 37 | 17256 | 1658 |
SCN5A,FGF13,LMCD1,GTF2IRD1,PKP2,ABAT,PRKCA,NOS1AP,FBXO32,DSG2,EHD3,PRKG1,PDE4D,CTTN,ERRFI1,ENO1,KCNB2,CHRM3,NOS3,PAK1,TRPM4,GSTM2,MSTN,ANK2,CALCRL,RYR2,GSTO1,ATP1B1,DSP,DOCK5,SMAD3,ITGA2,OXTR,TPM1,PPARGC1A,TRPC3,ATP2B4 |
| 3.088e-03 | -5.78 | GTATTAT,MIR-369-3P | MSigDB lists | GTATTAT,MIR-369-3P | 197 | 32 | 17377 | 1707 |
EFNB2,ZNF395,BMPR2,BACE1,ADAMTS6,PRKCA,FOXG1,TRPS1,NUMBL,FLRT3,AFF2,ACVR2A,AFAP1L2,PDE4D,VEGFC,PNRC1,KLHL3,DNAJC6,ELMOD1,UCHL3,ZFPM2,MBNL2,ZNF711,CEBPB,ADAMTS3,MAP2,TMEM117,ARHGAP28,CDH2,FNBP1L,PKIA,LARP1 |
| 3.088e-03 | -5.78 | V$TCF11MAFG_01 | MSigDB lists | V$TCF11MAFG_01 | 197 | 32 | 17377 | 1707 |
NUDT10,SV2B,MEIS2,MRC2,PLBD2,ARHGEF11,GRIK2,BLVRB,SHANK2,FGF12,IL13RA1,GRK6,ATP1B1,SEL1L3,PRR7,SATB1,DYNC1I1,PFN2,BEX2,HECTD2,PLS3,NUMBL,TECPR1,POPDC3,ALDOA,OSBPL5,LOXL4,PPARGC1A,ENO1,STON2,RIMS2,GAB2 |
| 3.088e-03 | -5.78 | GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_UP | 197 | 32 | 17377 | 1707 |
PLA2G4A,RGS16,INPPL1,CFH,GABRB2,CANX,DYNC1I1,TNKS1BP1,TXNRD3,KCNAB1,TRPC1,COL19A1,TSPAN13,POU2F2,SERPINH1,PDLIM7,PHLDB2,YAP1,COTL1,FRK,TPK1,DOCK7,PTPRJ,P4HA2,ENTPD7,RASGRF2,PAM,ERCC5,KLF5,DBP,SHOX2,SIX2 |
| 3.091e-03 | -5.78 | leg | COSMIC cancer mutations | leg | 983 | 122 | 17385 | 1698 |
EXPH5,NEK10,AVPI1,CFH,CNTNAP3,PTPN21,PKP2,NTRK3,ABAT,FAM13A,DNER,HMCN1,SLC9A7,CCNJ,CPNE2,COL22A1,EPB41L3,CPVL,ZFYVE28,PPFIBP1,BCL6,JAKMIP2,MET,SCN2A,TLN2,TMEM132E,PTPRE,DNAH5,KCNB2,INTU,TNK2,SESN2,ACVR1C,DCC,LRRC8B,PTPRU,KCNH5,SATB2,PRKCQ,TNS1,DSP,DOCK5,FRK,FGFR1,SPNS1,TMEM132B,ZNF711,ENPP1,TCF7L1,NRG3,ZNF266,PTPRJ,ITGBL1,ITGA2,TNFRSF1A,BMP1,PTPRS,ARHGAP28,ZBTB20,HGF,PPARGC1A,MAGI2,CNTN1,CARS,PCDH18,PTPRD,CLGN,TBC1D1,UBASH3B,PLAG1,MCTP2,IPO5,CBS,COL4A5,KCNC4,HSPA12B,SLC7A11,CNTN4,AFF2,PRKG1,ACTA2,LRP6,TSPAN12,ST8SIA1,PRR16,CHRM3,CARD6,SYNPO2,SLC37A1,HNF4G,MSTN,MCF2L2,GSTM4,PTPN13,DCHS1,ZNF605,NUAK2,FASN,AIG1,SDK1,SNAP25,GUCY1A2,SKAP1,PLCB1,GALNT14,KHDRBS2,ILDR2,CTIF,PTPRC,FAT4,TERT,ADAMTS3,PLXDC2,CDH17,SH3BP4,SLCO5A1,PTPRN2,SHOX2,CDH2,MME,CRISPLD1,PHC1 |
| 3.093e-03 | -5.78 | DYNLL1 (dynein light chain LC8-type 1) | protein interactions | 8655 | 223 | 36 | 17029 | 1718 |
DNM3,NTRK3,FAM117B,DYNC1I1,INPP1,STK24,TRPS1,EPB41L3,ERG28,CA2,ZNF354A,PPFIBP1,PPP2R2B,PRKACB,DZANK1,PAK1,NDUFA4L2,DLGAP1,PHLDB2,LCA5,GAPDH,MYO10,SHANK2,WWC1,VIM,RACK1,CTTNBP2NL,DSP,MAP1B,SNCA,DYRK1B,TERT,ALDOA,DLG2,KIF21A,PKIA |
| 3.106e-03 | -5.77 | V$OCT1_06 | MSigDB lists | V$OCT1_06 | 245 | 38 | 17377 | 1707 |
CARS,KLHL13,GALNT12,PLAG1,OTX1,MSR1,PLXNA2,NDRG2,NTRK3,CREB5,SATB1,SEMA6A,MECOM,FOXP2,LRRN1,MPPED2,BEND4,PDE4D,FIGN,SEMA6C,SCN3A,ATP2B1,MID2,BDNF,GPM6A,HNF4G,FOXN3,FGF12,PACSIN3,NFIA,ATP1B1,CLN5,NSD1,KIAA0355,GNAO1,DLG2,ZBTB20,OSBPL6 |
| 3.106e-03 | -5.77 | V$STAT4_01 | MSigDB lists | V$STAT4_01 | 245 | 38 | 17377 | 1707 |
NMNAT3,RUNX2,CACNG3,CCDC148,FN1,BCL6B,FAM81A,SATB1,FOXG1,TNKS1BP1,TNFRSF19,NEDD4,MECOM,MTUS1,EIF1,SGK1,ST8SIA1,PDE4D,NCAM1,FANK1,POU3F3,RIN2,VAV3,BDNF,RHOQ,USP2,HNF4G,NR4A1,CACNA1E,FGF12,TTYH2,PRKCB,PTK7,PPARGC1A,HOXB9,SHOX2,MAPK10,MEF2C |
| 3.109e-03 | -5.77 | human chr2q24.3 | chromosome location | human chr2q24.3 | 27 | 7 | 26185 | 1967 |
GALNT3,COBLL1,B3GALT1,SCN2A,FIGN,GRB14,SCN3A |
| 3.126e-03 | -5.77 | adipose tissue development | biological process | GO:0060612 | 33 | 9 | 17256 | 1658 |
DYRK1B,ZNF516,CSF1,ARID5B,XBP1,SELENOM,SH3PXD2B,PPARGC1A,SPART |
| 3.126e-03 | -5.77 | positive regulation of calcium ion transmembrane transporter activity | biological process | GO:1901021 | 33 | 9 | 17256 | 1658 |
GSTM2,CACNB2,ANK2,EHD3,RYR2,GSTO1,ATP1B1,HSPA2,CACNA2D1 |
| 3.126e-03 | -5.77 | AACTGGA,MIR-145 | MSigDB lists | AACTGGA,MIR-145 | 213 | 34 | 17377 | 1707 |
ARHGAP26,TRIM2,PSD3,RGS7,HERC6,SEL1L3,SEMA6A,ZFYVE9,CDR2L,DLX6,AFF2,C1QL4,SRGAP1,ACVR2A,SLC6A15,BEND4,GLIS1,SCN3A,EPB41L5,PHLDB2,RIN2,PXN,JPH1,NFE2L1,EFNA3,FNDC3A,SMAD3,CACHD1,BACH2,KIAA0355,KLF5,KIF21A,SEMA3A,KIF1B |
| 3.127e-03 | -5.77 | GSTM3 (glutathione S-transferase mu 3) | protein interactions | 2947 | 26 | 8 | 17029 | 1718 |
GSTM3,PLS1,BAG3,GSTM2,SH3GL2,ENO1,GSTM4,FOXA1 |
| 3.127e-03 | -5.77 | TRMT61A (tRNA methyltransferase 61A) | protein interactions | 115708 | 26 | 8 | 17029 | 1718 |
NPM1,MARS,LIMCH1,EVL,TLN2,ARHGEF11,RBFOX2,FHL2 |
| 3.130e-03 | -5.77 | V$SRF_Q6 | MSigDB lists | V$SRF_Q6 | 229 | 36 | 17377 | 1707 |
STAT5B,GRK6,EPHB1,PPP2R3A,PCDH7,NKX6-1,FOXP2,NAV1,MAP1A,RASD2,AGL,NKX2-1,PDLIM7,BDNF,MSX1,ATF4,NR4A1,TES,NPM3,TMEM126A,TMEM47,PRDM1,ASPH,HOXA1,RERE,SLC7A1,MAPKAPK2,MYADM,PDLIM3,MAP2K6,EMILIN2,SVIL,HOXD13,KIF1B,SIX2,LPP |
| 3.134e-03 | -5.77 | PDZ domain binding | molecular function | GO:0030165 | 78 | 16 | 17224 | 1680 |
PRKN,GNG12,GRIK2,CRIM1,FZD4,FZD8,RAPGEF2,PLEKHA1,BAIAP2,KCNJ4,TGFBR3,ADRB1,ACVR2A,ATP2B1,ATP2B4,FZD1 |
| 3.147e-03 | -5.76 | GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | 166 | 28 | 17377 | 1707 |
SERINC5,FARP1,TTC39B,TMEM65,UBASH3B,MVD,PTPN13,ARID5B,MCOLN3,FHL2,HIP1,ADAMTS6,BATF,PRKCA,ARRDC4,ABHD4,SESN1,TBC1D30,GPLD1,TRPS1,SMAD3,EPCAM,FGR,TMEM154,MYADM,GAS2L3,PLD1,DUSP1 |
| 3.169e-03 | -5.75 | upper_third | COSMIC cancer mutations | upper_third | 641 | 84 | 17385 | 1698 |
EXPH5,EPHA3,MVK,ZNF516,TMSB15A,ATP8A1,PTPN21,MCOLN3,ABHD13,PLXNA2,SPATS2L,COL14A1,DOCK2,PCLO,FSTL5,PCDH7,GPR15,SIPA1L2,KCNAB1,TACC2,MAP7,PCOLCE2,TMEM132E,VWA5A,DNAH5,MYT1,RASGRP1,SSH3,MYLK3,DCDC1,SHANK2,NFE2L1,PRKAR2B,PYGO1,ZNF711,PRKCB,WDR17,MRC2,FN1,ROBO2,GRB14,GABRG2,SETBP1,ARL2,SLC12A6,DYNC1I1,MTUS1,EFEMP1,MCOLN2,FRY,FUT9,VWDE,DSG2,SLC6A15,LOXL4,NPTXR,KIAA1211,RNF152,TMC7,CRIM1,COL4A4,CACNA1E,STAT4,RAPGEF2,KIAA1324L,SPATA13,NUAK2,RYR2,RASA3,SLITRK5,OBSCN,SMARCD3,PEX5L,ARHGAP32,TEX15,DOCK7,FBN1,CLDN12,FAT1,SVIL,PTPRN2,GEM,MMP16,ATP2B4 |
| 3.169e-03 | -5.75 | oesophagus-upper_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-upper_third-carcinoma-squamous_cell_carcinoma | 641 | 84 | 17385 | 1698 |
EXPH5,EPHA3,MVK,ZNF516,TMSB15A,ATP8A1,PTPN21,MCOLN3,ABHD13,PLXNA2,SPATS2L,COL14A1,DOCK2,PCLO,FSTL5,PCDH7,GPR15,SIPA1L2,KCNAB1,TACC2,MAP7,PCOLCE2,TMEM132E,VWA5A,DNAH5,MYT1,RASGRP1,SSH3,MYLK3,DCDC1,SHANK2,NFE2L1,PRKAR2B,PYGO1,ZNF711,PRKCB,WDR17,MRC2,FN1,ROBO2,GRB14,GABRG2,SETBP1,ARL2,SLC12A6,DYNC1I1,MTUS1,EFEMP1,MCOLN2,FRY,FUT9,VWDE,DSG2,SLC6A15,LOXL4,NPTXR,KIAA1211,RNF152,TMC7,CRIM1,COL4A4,CACNA1E,STAT4,RAPGEF2,KIAA1324L,SPATA13,NUAK2,RYR2,RASA3,SLITRK5,OBSCN,SMARCD3,PEX5L,ARHGAP32,TEX15,DOCK7,FBN1,CLDN12,FAT1,SVIL,PTPRN2,GEM,MMP16,ATP2B4 |
| 3.184e-03 | -5.75 | positive regulation of MAPK cascade | biological process | GO:0043410 | 553 | 73 | 17256 | 1658 |
EPHA3,NEK10,AVPI1,NTRK3,PRKCA,DDR1,STK24,GSDME,TLR3,DAB2IP,EPHB6,MET,TLR4,RASGRP1,PDGFRB,IGFBP3,GCNT2,FZD4,TGFA,LRRK2,ROR1,CD40,FGFR1,APELA,ERN1,MAP3K21,TNFRSF1A,DUSP19,HGF,DIRAS1,NRP1,MAPK10,MID1,TENM1,TYRO3,TNIK,NECAB2,EDA2R,FZD8,SORBS3,GAS6,TNFRSF10C,P2RY1,PKN1,EPHB1,TNFRSF19,TPD52L1,IGF1R,GHR,INAVA,IQGAP3,TNFRSF11A,SYK,SPRY2,HMGCR,FGFR4,PAK1,RAPGEF2,WWC1,DUSP9,PDE8A,GAREM1,TLR6,PLCB1,DKK1,GPR37,MAPKAPK2,PELI2,MAP2K6,BMP4,SEMA3A,CDH2,MAP3K20 |
| 3.196e-03 | -5.75 | YWATTWNNRGCT_UNKNOWN | MSigDB lists | YWATTWNNRGCT_UNKNOWN | 64 | 14 | 17377 | 1707 |
PCDH18,MAP2,NR4A1,GNAO1,CYTH3,VLDLR,TSC22D1,ATF3,PRDM1,SNAP25,FBXO36,AMPD1,CTNND2,HEY1 |
| 3.196e-03 | -5.75 | ROSS_AML_OF_FAB_M7_TYPE | MSigDB lists | ROSS_AML_OF_FAB_M7_TYPE | 64 | 14 | 17377 | 1707 |
TNIK,DNM3,ABCC4,PLOD2,GATA2,STXBP6,DNAJC6,FHL2,SQLE,LAPTM4B,SERPINI1,PROS1,TPM1,NEO1 |
| 3.208e-03 | -5.74 | skin-chest-malignant_melanoma | COSMIC cancer mutations | skin-chest-malignant_melanoma | 114 | 21 | 17385 | 1698 |
EFNB2,FER,TMEM63C,PTPRD,DCC,PTPN13,PTPN21,TNS1,EPHB1,KHDRBS2,PTPRC,TMEM132B,PTPRJ,ADAMTS3,PTK7,PTPRS,PTPRN2,ACVR2A,MET,PTPRE,CHRM3 |
| 3.216e-03 | -5.74 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | 174 | 29 | 17377 | 1707 |
RPS20,BCL7A,SIDT1,ZNF395,CKAP2,SETBP1,NPM1,COBLL1,SAV1,SKAP1,SEL1L3,BCL11A,CD37,ABLIM1,IKZF3,BACH2,PAIP2B,BACE2,MYC,TSPAN13,PIK3C2B,SP140,PTPRCAP,RRAS2,RASGRP1,RPS23,PKIA,PRKACB,DENND5B |
| 3.219e-03 | -5.74 | CRP (C-reactive protein) | protein interactions | 1401 | 56 | 13 | 17029 | 1718 |
QSOX1,FN1,CFH,CEMIP2,CNTNAP3,LAMB1,STC2,PTPRS,COL18A1,LAMC3,RPL26L1,RPL13A,B4GALT7 |
| 3.219e-03 | -5.74 | ENAH (ENAH, actin regulator) | protein interactions | 55740 | 56 | 13 | 17029 | 1718 |
DYRK1B,EVL,BCHE,FAT1,TES,APBB1,ABI3,YAP1,HECW2,ENAH,ATOH1,PFN2,BAIAP2 |
| 3.225e-03 | -5.74 | pallium development | biological process | GO:0021543 | 162 | 27 | 17256 | 1658 |
GNG12,FGF13,FEZ1,EFHC1,ATOH1,BCAN,FOXG1,PLCB1,FOXP2,FAT4,EOMES,TACC2,MFSD2A,LHX6,LAMB1,PTPRS,LRP6,BNIP3,DAB2IP,DLX2,NRP1,SEMA3A,CDH2,SLIT2,ATP2B4,POU3F3,NKX2-1 |
| 3.226e-03 | -5.74 | regulation of extent of cell growth | biological process | GO:0061387 | 101 | 19 | 17256 | 1658 |
PAK1,BDNF,FN1,FGF13,BMPR2,DCC,PLXNA2,NTRK3,MAP1B,NKX6-1,RND2,SEMA4F,PTPRS,SEMA3C,CTTN,NRP1,SPART,SEMA3A,SHTN1 |
| 3.229e-03 | -5.74 | F_BAR | prosite domains | PS51741 | 25 | 8 | 12060 | 1278 |
FER,PACSIN1,FNBP1L,FCHO2,PSTPIP2,FES,PACSIN3,SRGAP1 |
| 3.259e-03 | -5.73 | ovary-carcinoma | COSMIC cancer mutations | ovary-carcinoma | 948 | 118 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CELSR3,RECK,GPR65,OTX1,HECW2,ADD2,NPM1,CHUK,NTRK3,GRK6,ITPR2,PRKCA,DDR1,AARS,HMCN1,STK24,SIPA1L2,SPEG,RPS6KA2,RPS6KL1,MYO3B,ZNF521,KCNS3,ACVR2A,PPP2R2B,MET,DNAH5,FANK1,PRKACB,PDGFRB,FER,TNK2,MYLK3,MARK1,B3GALT1,PDK1,ACVR1C,TDRD3,FZD4,TES,LRRK2,SATB2,PRKCQ,ABCC2,ROR1,ACVR2B,SGK2,MFSD6,FRK,FGFR1,TSKU,SFXN1,DYRK1B,TCF7L1,PRKCB,PLK2,PTK7,ATP7B,ERN1,MAPK13,BMPR1A,STON2,MAST1,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,BACE1,CLSTN2,ARL2,PKN1,EPHB1,SPINK5,PHGDH,IGF1R,FRY,ADCK1,PDZD7,APLF,PRKCD,SGK3,PRKG1,SGK1,ALPK1,MOXD1,SYK,LRP3,FES,PAK1,TRPM4,FGFR4,BDNF,KCNQ3,BTNL9,NUAK2,OBSCN,STRADB,CDC42BPA,PRDM1,GALNT14,MBNL2,GLCE,MAPKAPK2,TRIB3,FGR,FAT4,FBN1,PKN3,AKT3,MAP2K6,UACA,NEK11,SVIL,KIF21A |
| 3.264e-03 | -5.72 | GO_NEGATIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE | 51 | 12 | 17377 | 1707 |
GBP1,CNKSR3,C1QL4,NDRG2,ATF3,DAB2IP,SYNJ2BP,SPRY4,ERRFI1,TLR4,SPRY2,DUSP1 |
| 3.264e-03 | -5.72 | MODULE_85 | MSigDB lists | MODULE_85 | 51 | 12 | 17377 | 1707 |
FGFR4,PTK7,ACVR2A,IL13RA1,EPHB6,ROR1,EPHB1,NRP1,LEPR,FGFR1,PDGFRB,F3 |
| 3.272e-03 | -5.72 | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP | MSigDB lists | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP | 182 | 30 | 17377 | 1707 |
MYCBP2,ARAP2,SCAMP1,KLHL13,TMEM65,DOCK1,RBFOX2,STAT4,ATF3,LCP2,CA13,RALGPS2,SLC7A11,THBS4,PLXDC2,RAI14,TNFRSF1A,GSTM3,RCN3,HPGD,RNF130,WWC2,PCK2,MAGI2,LIFR,KIF1B,SYK,RASGRP1,CHRM3,LPP |
| 3.272e-03 | -5.72 | KIM_MYC_AMPLIFICATION_TARGETS_UP | MSigDB lists | KIM_MYC_AMPLIFICATION_TARGETS_UP | 182 | 30 | 17377 | 1707 |
RIN2,MYCBP2,MXI1,ALOX5AP,PNP,EBPL,KCNQ3,LRRK2,PRRG1,SEMA6A,SLC19A2,CHN1,RSL24D1,RPL12,PDLIM3,MYC,PEMT,LAMB1,RGS10,MCC,SLC6A15,PCOLCE2,FAM155B,KLHL29,ENO1,AGL,GATM,RAPGEF5,RPS23,CNTN1 |
| 3.272e-03 | -5.72 | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN | 182 | 30 | 17377 | 1707 |
RIN2,EVL,MPP1,PSTPIP2,PPFIBP2,SELL,MAFB,KCTD12,LHPP,KBTBD11,SNCA,CEBPB,TYMP,ABLIM1,EPB41L3,FGR,IKZF3,CPVL,SLC22A18,OPN3,COL19A1,FIG4,FHIT,NRP1,APBA2,SPRY2,SYK,STOM,ABCG1,CRYL1 |
| 3.272e-03 | -5.72 | GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | MSigDB lists | GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | 182 | 30 | 17377 | 1707 |
ATL1,ANTXR2,LGALS3,KLHL3,CRIM1,STAT4,LRMP,TNFAIP8L2,TTYH2,NDRG2,PRDM8,SORBS3,GSTO1,IL13RA1,FAM198B,SFXN3,ABHD4,TLR6,SLCO3A1,RTN1,ID3,GSN,PTPRJ,NCKAP1L,PRCP,PPFIBP1,CLDN12,TNFRSF1A,FIG4,NCAM1 |
| 3.272e-03 | -5.72 | GSE22886_NAIVE_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_DC_UP | 182 | 30 | 17377 | 1707 |
BCL11B,MYCBP2,ITGB7,RPL26,SIDT1,IL32,ENO2,TES,RPL21,GATA3,SELL,RASA3,PRKCQ,STAT5B,SATB1,SKAP1,RPL13A,RPL34,ISG20,NELL2,CD37,ABLIM1,RPL28,GYPC,ALDOC,IPCEF1,PTPRCAP,RASGRP1,RPS23,DOCK9 |
| 3.272e-03 | -5.72 | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 182 | 30 | 17377 | 1707 |
UST,TRIM2,FARP1,COL6A2,RECK,ZCCHC24,BACE1,DNAJC6,PRRG1,ATF3,CDC42BPA,CRYBG3,DOK5,PPP2R3A,NT5DC2,GAS1,PCDH7,HOMER3,DKK1,FKBP9,IQCK,TMCO3,RPS6KA2,TGFBR3,ADAMTS3,DACT1,GULP1,CDH2,FNBP1L,SLIT2 |
| 3.272e-03 | -5.72 | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN | MSigDB lists | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN | 182 | 30 | 17377 | 1707 |
PAK1,ATP8A1,GDPD1,PANK1,CYP4V2,NFIA,RAB38,MFSD6,ABHD4,LDHD,ISG20,DEXI,SMAD3,CCDC120,ZNF827,KIAA1958,TRIB3,GSN,SOAT2,NCAM2,KIAA0355,GPR155,KAZN,GRB10,CTTN,CERS4,STXBP1,ATP2B4,RBMS2,PHC1 |
| 3.272e-03 | -5.72 | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | MSigDB lists | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | 182 | 30 | 17377 | 1707 |
MYCBP2,SEMA6B,TRIM2,ACVR1C,ATP8A1,LSM11,KIF5C,SLC1A3,FNDC3A,TNFRSF19,ILDR2,NCS1,SKI,GNAI1,NUMBL,PTPRJ,IGF1R,GPRIN1,NACC2,EHD3,KIAA0513,PGM2L1,LIN7A,DAB2IP,TMOD2,MARCKS,KLF9,ATP2B1,ATP1A3,MEF2C |
| 3.272e-03 | -5.72 | GSE29618_PDC_VS_MDC_UP | MSigDB lists | GSE29618_PDC_VS_MDC_UP | 182 | 30 | 17377 | 1707 |
RUNX2,ALOX5AP,SIDT1,PFKFB2,ATP8A1,SETBP1,COBLL1,RABAC1,NPC2,GAS6,EPHB1,RGS7,SEL1L3,ASPH,BCL11A,MAPKAPK2,RPS6KA2,MAP1A,SLC7A11,MAP2K6,ERN1,XBP1,SLC7A5,AHNAK2,PTPRS,TSPAN13,NRP1,PTPRCAP,TBC1D4,TBC1D8 |
| 3.278e-03 | -5.72 | response to starvation | biological process | GO:0042594 | 178 | 29 | 17256 | 1658 |
PRKAA2,FADS1,SESN2,ATF4,BMPR2,LRRK2,NUAK2,MARS,ATF3,GAS6,ADSSL1,SESN1,STK24,GABARAPL1,ASNS,PMAIP1,BHLHA15,CTSV,XBP1,SREBF1,PIK3C2B,CADPS2,ATG5,PPARGC1A,PCK2,LARP1,DDIT3,RRAGD,RNF152 |
| 3.287e-03 | -5.72 | nitrobenzene metabolic process | biological process | GO:0018916 | 4 | 3 | 17256 | 1658 |
GSTM3,GSTM2,GSTM4 |
| 3.287e-03 | -5.72 | substrate-dependent cerebral cortex tangential migration | biological process | GO:0021825 | 4 | 3 | 17256 | 1658 |
NRP1,SEMA3A,SLIT2 |
| 3.287e-03 | -5.72 | regulation of establishment of T cell polarity | biological process | GO:1903903 | 4 | 3 | 17256 | 1658 |
GSN,RIPOR2,DOCK8 |
| 3.287e-03 | -5.72 | neuroligin clustering involved in postsynaptic membrane assembly | biological process | GO:0097118 | 4 | 3 | 17256 | 1658 |
NRXN1,MAGI2,CDH2 |
| 3.287e-03 | -5.72 | axo-dendritic protein transport | biological process | GO:0099640 | 4 | 3 | 17256 | 1658 |
KIF5C,DLG2,MAP1A |
| 3.287e-03 | -5.72 | positive regulation of heart rate by epinephrine-norepinephrine | biological process | GO:0001996 | 4 | 3 | 17256 | 1658 |
PDE4D,TPM1,ADRB1 |
| 3.287e-03 | -5.72 | creatinine metabolic process | biological process | GO:0046449 | 4 | 3 | 17256 | 1658 |
STAT5B,MME,GHR |
| 3.287e-03 | -5.72 | hematopoietic stem cell migration | biological process | GO:0035701 | 4 | 3 | 17256 | 1658 |
BCL11B,GAS6,GPLD1 |
| 3.297e-03 | -5.71 | Protein digestion and absorption | KEGG pathways | hsa04974 | 89 | 18 | 7161 | 730 |
COL9A3,SLC3A2,COL6A2,COL4A3,SLC36A1,COL4A4,COL18A1,COL4A5,ATP1B1,COL14A1,COL27A1,COL22A1,PRCP,SLC1A5,COL9A2,SLC16A10,MME,ATP1A3 |
| 3.297e-03 | -5.71 | Protein digestion and absorption | KEGG pathways | ko04974 | 89 | 18 | 7161 | 730 |
COL9A3,SLC3A2,COL6A2,COL4A3,SLC36A1,COL4A4,COL18A1,COL4A5,ATP1B1,COL14A1,COL27A1,COL22A1,PRCP,SLC1A5,COL9A2,SLC16A10,MME,ATP1A3 |
| 3.302e-03 | -5.71 | positive regulation of locomotion | biological process | GO:0040017 | 536 | 71 | 17256 | 1658 |
AMOTL1,ACVR1,DOCK1,RHOD,ATP8A1,COL18A1,GATA3,NTRK3,PRKCA,SEMA6A,F3,TCAF2,ITGB3,DAB2IP,MET,SLIT2,DOCK8,SNAI2,PDGFRB,FER,GCNT2,PREX1,WNT11,RARRES2,CD40,DOCK5,FGFR1,IRS2,SMAD3,CXCL10,NCKAP1L,CCBE1,PLK2,APELA,ITGA2,LAMB1,HGF,SEMA3C,NRP1,CHMP4C,FN1,LGALS3,BMPR2,BVES,ITGA6,GAS6,SEMA4F,IGF1R,GATA2,RRAS2,SPRY2,NOS3,VEGFC,PAK1,EPB41L5,RAPGEF2,RACK1,GPLD1,PTPRC,FGR,DOCK7,MYADM,RIPOR2,TERT,AKT3,CSF1,THBS4,XBP1,BMP4,SEMA3A,SHTN1 |
| 3.304e-03 | -5.71 | transmembrane transporter activity | molecular function | GO:0022857 | 1069 | 131 | 17224 | 1680 |
CACNG3,SIDT1,FLVCR2,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,CACNB4,SLCO3A1,SLC9A7,NCS1,KCNAB1,KCNN2,SLC16A2,SLC22A18,SLC10A7,KCNS3,SERINC2,TRPC1,CNNM2,SLC2A12,TMEM37,GPM6A,KCNIP3,SLC3A2,ABCC4,SLC9C1,ATOX1,JPH1,SLC25A28,ABCC2,KCND3,SFXN1,SLC7A1,KCNMB4,ATP7B,MFSD4A,SLC9B1,KCNV1,SV2B,SCN5A,TMEM63C,GABRB2,SCN8A,SLC25A27,ATP6V1E2,SLC36A4,SLC1A3,MCOLN2,SLC30A4,SLC7A11,ABCA5,CACNB2,LRP6,SLC16A9,NIPAL2,SLCO4C1,FAM155A,NDUFA4L2,SLC37A1,KCNQ3,SLC36A1,SLC27A2,RYR2,TTYH2,STEAP1,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,CDH17,TRPC3,SLC7A2,SLC19A2,SLC22A17,CHRNA5,FAM155B,SCN2A,ATP6AP1L,KCNB2,SCN3A,LRRC8B,KCNH5,SFXN4,SLC39A8,CHRNA6,ATP1B1,GJC1,SLC39A14,ASIC1,KCNG1,DISP1,DENND5B,ANO10,SERINC5,SLC6A9,GABRG2,SLC12A6,GABRR2,GAS6,SFXN3,SLC35G2,KCNC4,MCU,SLC35F1,LRRC55,KCNJ4,SCN1B,KCNMB3,SLC6A15,SLC45A3,ATP2B1,TRPM4,SLC40A1,CACNA1E,GRID1,RASA3,SLC7A5,SLCO5A1,SLC18B1,GRIN2D,SLC22A15,SLC1A5,CACNA2D1,ATP2B4,SLC16A10,ATP1A3,SLC43A1,ABCG1 |
| 3.311e-03 | -5.71 | GO_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_BIOMINERAL_TISSUE_DEVELOPMENT | 71 | 15 | 17377 | 1707 |
SMAD3,PLA2G4A,TRPM4,ENPP1,ACVR1,BMPR2,CD276,TFAP2A,ACVR2A,ACVR2B,BMPR1A,GAS6,BMP4,BMP6,MEF2C |
| 3.311e-03 | -5.71 | ROSS_AML_WITH_PML_RARA_FUSION | MSigDB lists | ROSS_AML_WITH_PML_RARA_FUSION | 71 | 15 | 17377 | 1707 |
MRC2,CHN2,ASNS,MAP1A,FGF13,AFF2,CCNA1,SMARCD3,CLMN,HGF,GRB10,CERS4,ITPR2,STXBP1,PGBD5 |
| 3.311e-03 | -5.71 | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | MSigDB lists | BRUECKNER_TARGETS_OF_MIRLET7A3_DN | 71 | 15 | 17377 | 1707 |
EFEMP1,RIN2,GALNT1,GPRC5B,FN1,PMEPA1,PLK2,TMPRSS9,MATN2,ATOX1,MORC4,VIM,COTL1,PTGES,DCBLD1 |
| 3.314e-03 | -5.71 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | 190 | 31 | 17377 | 1707 |
PAK1,ALDH2,RUNX2,TMEM43,PSTPIP2,NDRG2,KCTD12,IL13RA1,SCD,CTBP2,VIM,ATF3,SPATS2L,CREB5,COTL1,ATP1B1,DOCK5,RTN1,GSN,CPVL,NACC2,ALDOA,RGS10,SH3BP4,RAB31,RNF130,PTPRE,ENO1,COL9A2,CEBPD,FZD1 |
| 3.314e-03 | -5.71 | GSE19512_NAUTRAL_VS_INDUCED_TREG_DN | MSigDB lists | GSE19512_NAUTRAL_VS_INDUCED_TREG_DN | 190 | 31 | 17377 | 1707 |
PLA2G4A,MAN2B2,RGS16,PNP,REL,SSX1,KCTD12,GSTO1,ABCC2,TMEM47,CD7,KBTBD11,LEPR,F3,GALNT3,GSN,TLR3,IGF1R,INSIG1,RND3,NOVA2,MYC,KIAA0513,FAM149A,MARCKS,RPS12,MET,TSHR,PTPRE,CEBPD,CTH |
| 3.314e-03 | -5.71 | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP | MSigDB lists | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP | 190 | 31 | 17377 | 1707 |
LONRF1,SKAP2,LGALS3,FN1,EML6,ST14,LPCAT2,PSTPIP2,ESRP1,LITAF,CTBP2,PALLD,ABHD4,PFN2,ARHGAP44,CACHD1,KCTD15,ASNS,PLAGL1,MCF2L,GNB4,TSC22D1,ATRNL1,HPGD,GRB10,LRRK1,PLTP,TTC39A,CSRP2,IGFBP3,HEY1 |
| 3.314e-03 | -5.71 | GSE20715_0H_VS_48H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_UP | 190 | 31 | 17377 | 1707 |
SLC40A1,ARAP2,ZNF395,COL4A3,CYTH3,LRMP,CR2,SLC25A28,PRDM1,PLEKHA1,FAM198B,SATB1,SESN1,TSPAN17,PLEKHB1,TBC1D19,PTPRC,CD37,RPS6KA2,TRIM34,PLAGL1,PRKCB,DACT1,ZNF521,RAB31,FAM107B,POF1B,MAOA,LIMCH1,FIG4,PTPRE |
| 3.314e-03 | -5.71 | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_DN | MSigDB lists | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_DN | 190 | 31 | 17377 | 1707 |
CXCR5,FADS1,PCDH18,ENAM,MEIS2,ROBO2,COL4A3,TSPAN15,NLRP14,GRID1,LITAF,AK4,CD40,DYNC1I1,COL27A1,SCIN,CACHD1,KIAA0895,UNC13B,SERPINH1,CMPK2,TBC1D4,SHOX2,MID1,NTNG1,GFRA1,MED12L,ATP1A3,RNF152,CES3,PARP9 |
| 3.314e-03 | -5.71 | GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN | 190 | 31 | 17377 | 1707 |
MYCBP2,RNF145,IGFBP6,CSN2,NR4A1,TGFA,FZD8,DHCR24,VAMP8,LRRK2,CYP4V2,RHPN2,LRRC49,CCDC85A,DOCK5,ASPH,DSP,HERPUD1,GAS1,TSKU,F3,GBGT1,BAG3,KCNJ4,GPRC5B,ZNF521,SLC6A15,HGF,GFRA1,IL1RAP,CEBPD |
| 3.314e-03 | -5.71 | GO_CONNECTIVE_TISSUE_DEVELOPMENT | MSigDB lists | GO_CONNECTIVE_TISSUE_DEVELOPMENT | 190 | 31 | 17377 | 1707 |
CREB3L2,MSX1,ZNF516,RUNX2,SMAD9,BMPR2,ARID5B,SATB2,CHSY1,BMP6,FGFR1,COL27A1,GPLD1,DYRK1B,CSF1,XBP1,BMP1,ACTA2,LRP6,SH3PXD2B,DLX2,BMPR1A,BMP4,SERPINH1,PPARGC1A,SHOX2,FOXA1,PDGFRB,SNAI2,SIX2,MEF2C |
| 3.314e-03 | -5.71 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | 190 | 31 | 17377 | 1707 |
SUSD3,HBG2,SH3BP2,RUNX2,ATF4,SKAP2,LGALS3,PRSS16,LITAF,FHL2,ATF3,PRDM1,LACC1,MFSD6,NEDD4,GABARAPL1,PYCR1,CEBPB,AHRR,SUGT1,ENPP1,MGAT1,MARVELD2,CLDN12,DSG2,DUSP19,SLC16A9,MED7,EPHB6,MORN4,SMYD3 |
| 3.320e-03 | -5.71 | Glycos_transf_2 | pfam domains | PF00535 | 27 | 8 | 17054 | 1666 |
GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT18,GALNT14 |
| 3.334e-03 | -5.70 | V$ZIC1_01 | MSigDB lists | V$ZIC1_01 | 246 | 38 | 17377 | 1707 |
CACNG3,BMPR2,GABRG2,CBLN1,EYA4,CYP26A1,MTUS1,ATXN7L1,NELL2,ZNF362,MAP1A,KAZN,PCBP4,FRAS1,GHR,BCL6,PACSIN1,FMNL2,FES,GLI1,NDUFA4L2,PTCH2,ATL1,UNC5C,CTTNBP2NL,UCHL3,MAP1B,NEGR1,KLF12,GNAO1,PLXDC2,PTK7,GRIN2D,SPRY4,NKX2-8,HOXB9,ATP2B4,CTNND2 |
| 3.337e-03 | -5.70 | DNM1 (dynamin 1) | protein interactions | 1759 | 76 | 16 | 17029 | 1718 |
FER,DNM3,SH3GL2,NPM3,SH3BP4,PACSIN3,GRIN2D,RACK1,CTTN,ZBBX,SNAP25,PACSIN1,PRKCA,PFN2,SNX9,TBC1D2 |
| 3.344e-03 | -5.70 | GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | MSigDB lists | GO_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 889 | 112 | 17377 | 1707 |
PLA2G4A,ACVR1,ACSL1,ID1,IL15,RBFOX2,RGS20,MSR1,GATA3,ASS1,NPM1,CEBPA,STAT5B,NTRK3,ITPR2,ABAT,F3,FBXO32,ASNS,TLR3,CHRNA5,PMAIP1,AKAP7,GSTM3,PDE4D,SLIT2,PRKACB,PDGFRB,CYP1B1,FZD1,SLC3A2,SMAD9,PTPRU,NR6A1,GJB2,LRRK2,ADCY1,CHRNA6,PRKAR2B,PRKCQ,ABCC2,ASPH,SNCA,GNAI1,SMAD3,GSN,CXCL10,ATP7B,ITGA2,PAM,OXTR,PPARGC1A,LIFR,NR3C2,PSPH,HEY1,MEF2C,FN1,GABRB2,SELL,GABRG2,P2RY1,MLC1,BMP6,NEDD4,NKX6-1,HMGCS1,CA2,EEF2,ZNF354A,SLC7A11,BCHE,DSG2,GHR,STC2,SREBF1,SGK1,ADCY6,GRIP1,LRP6,KLF9,ERRFI1,SMAD6,AGL,ATP2B1,DUSP1,FGFR4,GSTM2,MSTN,HNF4G,NR4A1,RAPGEF2,ESRRG,FHL2,RYR2,SDK1,MGMT,GPLD1,CEBPB,MMP15,ID3,PMEPA1,TERT,GNAO1,BMP4,TRPC3,SMYD3,PTGES,FOXA1,BTRC,ATP2B4,ATP1A3 |
| 3.347e-03 | -5.70 | KIM_ALL_DISORDERS_CALB1_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_CALB1_CORR_UP | 516 | 70 | 17377 | 1707 |
DOC2A,MYCBP2,CACNG3,SCAMP1,DUSP8,ASS1,NRXN1,DOCK3,CANX,AARS,CHST10,RTN1,NELL2,IDI1,ASNS,KCNAB1,REEP1,SCRN1,ATRNL1,MARCKS,EPHB6,SYNGR3,ZNF365,RAPGEF5,PRKACB,GPM6A,GARS,CAP2,DSTN,NFE2L1,BNIP3L,PRKAR2B,ATP1B1,RNF44,GNAI1,PLK2,ALDOA,AHNAK2,SERPINI1,INPP5F,NECAB2,ENO2,DHCR24,GABRG2,RGS7,PFN2,DYNC1I1,FOXG1,CHN1,EEF2,SLC6A15,BNIP3,TBC1D9,FBXL2,STXBP1,ATP2B1,PNMA2,HMGCR,B4GALT6,PAK1,MGST3,FHL2,SLITRK5,RYR2,SNAP25,RABAC1,BEX4,KIAA0513,PTPRN2,ATP1A3 |
| 3.349e-03 | -5.70 | alcohol biosynthetic process | biological process | GO:0046165 | 94 | 18 | 17256 | 1658 |
PRKAA2,MVK,MVD,DHCR24,ISYNA1,CYP51A1,IDI1,ERG28,HMGCS1,INSIG1,MSMO1,ACER2,SRD5A3,SQLE,MOXD1,PCK2,DHCR7,HMGCR |
| 3.353e-03 | -5.70 | GSE27859_MACROPHAGE_VS_DC_UP | MSigDB lists | GSE27859_MACROPHAGE_VS_DC_UP | 159 | 27 | 17377 | 1707 |
GCA,LPAR2,PNP,RNF144A,RAPGEF2,KCNH5,LSM11,DSTN,CALCRL,ATF3,PRDM1,RAB38,LCP2,ARRDC4,PHGDH,KREMEN1,SLCO3A1,DCBLD2,MCOLN2,MAPKAPK2,KPNA3,PIK3AP1,PLK2,EIF1,STXBP1,SNX10,JAM2 |
| 3.353e-03 | -5.70 | NUYTTEN_NIPP1_TARGETS_DN | MSigDB lists | NUYTTEN_NIPP1_TARGETS_DN | 799 | 102 | 17377 | 1707 |
EXPH5,PHACTR3,TRIM2,UGDH,ABHD13,GRK6,DDR1,SCIN,FAM131B,CDS1,SKI,TUBB4A,EPCAM,CHRNA5,PDZD8,RAP2A,EEPD1,SERINC2,SCRN1,STEAP3,SERPINH1,RCAN3,SNX10,CYP1B1,SUSD3,FER,ANTXR2,FZD4,DSTN,SOX21,FAM84A,GJB2,PREX1,SYNJ2BP,ROR1,MFSD6,SESN1,ASPH,NT5DC2,GNAI1,SFXN1,SLC7A1,CAMK2N1,IQCK,GPRC5B,HPSE,RGS10,ARHGAP28,KLF5,MAPK13,SPRY4,VASH2,MBOAT2,LPP,PCDH18,MYO1D,MXI1,BMPR2,IGFBP6,GCAT,BIK,DHCR24,IPO5,IGF2BP2,SLC36A4,SORBS3,ISYNA1,SLC12A6,NDFIP2,PHLDA2,RNF141,KIAA1958,PRTFDC1,ZBTB38,HS3ST5,RALGAPA2,LIMCH1,SLC16A9,LOXL4,FAM84B,NCEH1,ZNF518B,SYK,GPR161,CHRM3,B4GALT6,HMGCR,QSOX1,SLC40A1,FOXN3,TCEA3,TMTC4,TTYH2,PRICKLE1,MBNL2,GALNT3,TMCO3,TMEM154,RAI14,PTGES,FOXA1,ABCG1 |
| 3.355e-03 | -5.70 | V$TCF11_01 | MSigDB lists | V$TCF11_01 | 238 | 37 | 17377 | 1707 |
EXPH5,SORBS1,JDP2,HEBP1,NTRK3,CREB5,GRK6,TSPAN17,HECTD2,FOXP2,MAP1A,ABI3BP,JAKMIP2,BEND4,PDE4D,MYT1,RIMS2,GAB2,MID2,BDNF,SLC3A2,SLITRK2,FHL2,SMARCD3,PEX5L,AIG1,SATB2,ATP1B1,FBXO36,MBNL2,GNAI1,EBF1,MAP2,DLG2,NRP1,KIF1B,PCSK5 |
| 3.364e-03 | -5.69 | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | MSigDB lists | HELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS | 78 | 16 | 17377 | 1707 |
QSOX1,BDNF,IL32,TGFA,ASS1,NPC2,PDLIM3,FBN1,ABI3BP,FAT1,SMTN,CDH2,CPE,FILIP1,IGFBP3,ABCG1 |
| 3.364e-03 | -5.69 | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | MSigDB lists | ONDER_CDH1_SIGNALING_VIA_CTNNB1 | 78 | 16 | 17377 | 1707 |
MICAL2,MYO1B,ARHGAP22,SYBU,LMCD1,FERMT2,SLC46A3,MAP1B,BEX4,FBN1,STC2,ACTA2,TSPAN13,SEMA3C,TPM1,IGFBP3 |
| 3.365e-03 | -5.69 | AFFAR_YY1_TARGETS_UP | MSigDB lists | AFFAR_YY1_TARGETS_UP | 206 | 33 | 17377 | 1707 |
CFH,PRSS35,ABAT,TPD52L1,CBLN1,BMP6,EFEMP1,IL17D,PMAIP1,TSC22D1,COL19A1,NAP1L3,PLTP,PERP,ZNF385A,DUSP1,BDNF,CD55,PFKFB2,EFNA3,ST6GALNAC3,CPEB1,NRG3,PDLIM3,PLOD2,RND3,GBP1,BMP4,TPM1,MAPK10,SPOCK3,CTNND2,SFN |
| 3.369e-03 | -5.69 | BROWNE_HCMV_INFECTION_16HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_16HR_DN | 85 | 17 | 17377 | 1707 |
PDLIM7,CACNA1E,MVD,CHN1,TGFBR3,MAP2K6,SVIL,NRP1,TPM1,FBXL2,SERPINH1,SMAD6,SEMA3A,MAGI2,ZFP36L2,SLIT2,ATP2B4 |
| 3.374e-03 | -5.69 | GPCR_2_extracellular_dom | interpro domains | IPR001879 | 27 | 8 | 18492 | 1811 |
CALCRL,ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRL2,ADGRB2,ADGRL1 |
| 3.374e-03 | -5.69 | Glyco_trans_2-like | interpro domains | IPR001173 | 27 | 8 | 18492 | 1811 |
GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT18,GALNT14 |
| 3.374e-03 | -5.69 | GPCR_2_extracell_dom_sf | interpro domains | IPR036445 | 27 | 8 | 18492 | 1811 |
CALCRL,ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRL2,ADGRB2,ADGRL1 |
| 3.375e-03 | -5.69 | AAAGGGA,MIR-204,MIR-211 | MSigDB lists | AAAGGGA,MIR-204,MIR-211 | 214 | 34 | 17377 | 1707 |
BCL11B,FARP1,RUNX2,CELSR3,SEC24D,KLHL13,ZCCHC24,PLAG1,FAM117B,CREB5,NOVA1,CHD5,CHN2,FRY,FRAS1,REEP1,NBEA,ADCY6,RTKN2,EPHB6,ATP2B1,ARAP2,GPM6A,MYO10,ESRRG,SATB2,RERE,TCF7L1,KLF12,NCOA7,PPARGC1A,CDH2,MLLT3,KCTD1 |
| 3.375e-03 | -5.69 | GO_REGULATED_EXOCYTOSIS | MSigDB lists | GO_REGULATED_EXOCYTOSIS | 214 | 34 | 17377 | 1707 |
DOC2A,FN1,SYT12,VAMP8,GAS6,SYT14,PCLO,PCDH7,SCIN,RAB11FIP5,UNC13B,GATA2,ITGB3,RAB26,CADPS2,PROS1,STXBP1,SYK,RASGRP1,RIMS2,VEGFC,QSOX1,ABCC4,RAPGEF4,PHACTR2,RARRES2,SNAP25,TRIM9,ALDOA,RAB31,HGF,SEPT5,TC2N,SNPH |
| 3.375e-03 | -5.69 | cellular response to organonitrogen compound | biological process | GO:0071417 | 501 | 67 | 17256 | 1658 |
PRKN,SORBS1,ID1,ASS1,STAT5B,ITPR2,PDE4D,TLR4,TSHR,SLIT2,PRKACB,FER,SESN2,ATF4,UROS,LRRK2,ADCY1,PRKAR2B,SESN1,SNCA,IRS2,ENPP1,EIF4EBP1,GNB4,MAPK13,KLF5,PPARGC1A,RRAGD,MEF2C,GNG12,GABRB2,IPO5,GABRG2,ATP6V1E2,NKX6-1,IGF1R,CA2,GHR,PRKCD,SREBF1,ADCY6,ERRFI1,PCK2,TRPM4,PAK1,GSTM2,PXN,RHOQ,NR4A1,RAPGEF2,RYR2,MARS,TLR6,CPEB1,BAIAP2,GPLD1,CEBPB,TRIB3,FBN1,XBP1,RAB31,SH3BP4,TBC1D4,LARP1,ATP2B4,CACNA2D1,ATP1A3 |
| 3.376e-03 | -5.69 | GO_SMALL_MOLECULE_METABOLIC_PROCESS | MSigDB lists | GO_SMALL_MOLECULE_METABOLIC_PROCESS | 1665 | 196 | 17377 | 1707 |
NMNAT3,MVK,UGT8,ACSL1,ADAL,PDE1B,AASS,UGDH,LDLR,ASS1,STAT5B,CEBPA,ABAT,BCAN,CACNB4,CA8,AARS,QPRT,CYP51A1,TYMP,AADAT,FAAH2,NDUFB8,PLTP,ENO1,CYP1B1,GLDC,SESN2,ATF4,ALDH1L2,LRRK2,PRKAR2B,CA13,PYCR1,AK1,ENPP1,HPSE,INSIG1,ENPP6,ALDOA,TNFRSF1A,BDH2,DSEL,PPARGC1A,TNFSF4,SPOCK3,CRYL1,HS6ST3,UST,PRKAA2,CARS,GPT2,MOCOS,INPPL1,EHHADH,ALOX5AP,OTOGL,CYP2J2,ST6GAL1,ELOVL7,OLAH,DHCR24,CYP4V2,SCD,ISYNA1,SLC1A3,CHSY1,PHGDH,ADSSL1,PRTFDC1,CA2,MSMO1,BCHE,PDE10A,HS3ST5,SREBF1,ADCY6,SLC16A9,NOS3,HMGCR,CHSY3,FADS1,RHOQ,PNP,SLC27A2,VLDLR,FASN,CALCRL,PDE8A,LHPP,NPC2,PLCB1,AMDHD1,GLCE,DAGLA,MAPKAPK2,GSTO2,HK2,MPP2,SQLE,DHCR7,PANK3,AMPD1,MME,ACSM3,PLA2G4A,NUDT10,ELOVL4,LPCAT2,XYLT1,SLC7A2,LPIN3,NUDT12,SLC19A2,CYP26A1,CDS1,IDI1,ASNS,KMO,ALDOC,ALDH1L1,FABP6,PDE4D,FHIT,MDH1B,GATM,CTH,VNN2,GAPDH,GARS,PDK1,UROS,EBPL,PFKFB2,CYB5R2,MVD,PANK1,ADCY1,ACO1,GSTO1,ATF3,ATP1B1,MAGI3,TPK1,WARS,SNCA,IRS2,TDO2,PEMT,INPP4B,PAM,HPGD,P4HA1,CYP2U1,HS3ST3B1,MBOAT2,PSPH,MAN2B2,ENO2,GCAT,CBS,INPP1,HMGCS1,SOAT2,FUT9,GHR,PCK2,ESD,SYK,SMPDL3A,B4GALT6,PFKFB4,ALDH2,MPP1,ELOVL3,OGDHL,AK4,MARS,GUCY1A2,LEPR,LRAT,SMPDL3B,GPLD1,DDAH1,ACER2,SRD5A3,OSBPL5,XBP1,SLC7A5,PGM2L1,DLG2,HK1,CMPK2,PTGES,OCLN,ABCG1 |
| 3.380e-03 | -5.69 | Assembly of collagen fibrils and other multimeric structures | REACTOME pathways | R-HSA-2022090 | 60 | 13 | 10287 | 971 |
COL9A3,COL6A2,COL4A3,COL4A4,ITGA6,CTSV,BMP1,COL18A1,COL4A5,LOXL4,COL9A2,COL27A1,TLL2 |
| 3.384e-03 | -5.69 | SLAMF1 (signaling lymphocytic activation molecule family member 1) | protein interactions | 6504 | 111 | 21 | 17029 | 1718 |
EPHA3,RAB3B,CELSR1,CNTNAP3,PLXNA2,PTPRC,CACHD1,FGR,MYADM,CHRNA5,IGF1R,BCHE,FRAS1,FAT1,MOXD1,GALNT18,CPE,LIFR,OCLN,ATP1A3,PCSK5 |
| 3.410e-03 | -5.68 | MODULE_44 | MSigDB lists | MODULE_44 | 312 | 46 | 17377 | 1707 |
PRSS16,FN1,ALOX5AP,IL32,ST6GAL1,ITGA6,SELL,ZIC2,LCP2,SATB1,FOXG1,DOCK2,GAS1,DDIT4,CD53,MTUS1,EPB41L3,ABLIM1,TYMP,CPVL,BCL6,PTPRCAP,CPE,PRKACB,CYP1B1,LAMP3,IGFBP3,COL6A2,PNRC1,PFKFB2,CRIM1,PTPN6,KCND3,DSP,FGFR1,ISG20,PTPRC,CD37,ENPP1,RAB31,RGS10,MAOA,ZBTB20,PAX9,OCLN,MME |
| 3.417e-03 | -5.68 | cellular response to corticosteroid stimulus | biological process | GO:0071384 | 59 | 13 | 17256 | 1658 |
FBXO32,MSTN,EIF4EBP1,ASS1,ABCC2,KLF9,ERRFI1,PCK2,ZFP36L2,SMYD3,ATP2B1,DDIT4,HEY1 |
| 3.417e-03 | -5.68 | actin filament bundle assembly | biological process | GO:0051017 | 59 | 13 | 17256 | 1658 |
RND2,SORBS1,RND3,RHOBTB1,RHOD,EPS8,MYO1B,ADD2,PLS1,MARCKS,SPIRE1,BAIAP2,PLS3 |
| 3.419e-03 | -5.68 | BATF (basic leucine zipper ATF-like transcription factor) | protein interactions | 10538 | 21 | 7 | 17029 | 1718 |
CEBPA,ATF3,DBP,ATF4,BATF,DDIT3,BATF3 |
| 3.431e-03 | -5.67 | Cardiac conduction | REACTOME pathways | R-HSA-5576891 | 142 | 24 | 10287 | 971 |
SCN5A,KCNIP3,CACNG3,FGF13,SCN8A,FGF12,RYR2,ITPR2,KCND3,ATP1B1,CACNB4,ASPH,KCNK15,KCNJ4,SCN1B,CACNB2,WWTR1,TRPC1,SCN2A,SCN3A,CACNA2D1,ATP2B1,ATP2B4,ATP1A3 |
| 3.436e-03 | -5.67 | GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_UP | MSigDB lists | GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_UP | 167 | 28 | 17377 | 1707 |
TFCP2L1,NMNAT3,SLC40A1,EML6,ACTL8,LRMP,YPEL2,PRKCQ,RNF24,FAM117B,ACVR2B,LCP2,TAF4B,RNF44,SATB1,RERE,IRS2,HEYL,ADRB1,BCL6,FAM84B,RAB27B,IQSEC2,STON2,MMP16,DCBLD1,CEBPD,MEF2C |
| 3.436e-03 | -5.67 | BROWNE_HCMV_INFECTION_18HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_18HR_DN | 167 | 28 | 17377 | 1707 |
FADS1,GPR176,OPLAH,RIN2,COL6A2,RAB3B,ID1,UROS,FGF13,PTPRD,RECK,GAS6,GUCY1A2,DENND3,CTIF,MSC,RPS6KA2,MAP1A,INSIG1,PRKCB,SLC22A18,MYC,PCGF2,DHRS12,EPHB6,ATP2B4,PDGFRB,DUSP1 |
| 3.436e-03 | -5.67 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP | 167 | 28 | 17377 | 1707 |
SUSD3,ITGB7,MXI1,ITPRIP,ARHGEF11,UBASH3B,EFHC2,TCEA3,RASA3,DDIT4,ISG20,NAP1L5,IRS2,BAG3,PRKCB,SLC22A18,PELI2,TSC22D1,ZBTB20,FHIT,PDE4D,SUSD4,SMYD3,ZFP36L2,PERP,LPP,PCSK5,DUSP1 |
| 3.437e-03 | -5.67 | GO_AXIS_ELONGATION | MSigDB lists | GO_AXIS_ELONGATION | 27 | 8 | 17377 | 1707 |
PTK7,LRP6,YAP1,HOXD13,WNT11,BMP4,MAGI2,SPRY2 |
| 3.437e-03 | -5.67 | IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_UP | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_UP | 27 | 8 | 17377 | 1707 |
FERMT2,COBLL1,BNIP3,RARRES2,ACSL1,RAPGEF2,FOXN3,PCSK6 |
| 3.437e-03 | -5.67 | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | MSigDB lists | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_UP | 27 | 8 | 17377 | 1707 |
EFNB2,EPB41L3,IGFBP6,KCNG1,RIMS2,ISG20,PCDH7,IGSF3 |
| 3.437e-03 | -5.67 | GO_NEGATIVE_REGULATION_OF_AXON_GUIDANCE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_AXON_GUIDANCE | 27 | 8 | 17377 | 1707 |
SEMA6B,SEMA4F,SEMA3C,NRP1,SEMA3A,SLIT2,SEMA6A,SEMA6C |
| 3.437e-03 | -5.67 | GO_CHEMOREPELLENT_ACTIVITY | MSigDB lists | GO_CHEMOREPELLENT_ACTIVITY | 27 | 8 | 17377 | 1707 |
SEMA6B,NRG3,SEMA4F,FLRT3,SEMA3C,SEMA3A,SEMA6A,SEMA6C |
| 3.449e-03 | -5.67 | central_nervous_system-brainstem-glioma-astrocytoma | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma | 4 | 3 | 17385 | 1698 |
ACVR1,TERT,KIAA1549 |
| 3.451e-03 | -5.67 | CortBP2 | pfam domains | PF09727 | 4 | 3 | 17054 | 1666 |
CTTNBP2NL,CTTNBP2,FILIP1 |
| 3.454e-03 | -5.67 | SH2 | pfam domains | PF00017 | 100 | 19 | 17054 | 1666 |
FER,VAV3,SH3BP2,INPPL1,GRB14,SH2D2A,PTPN6,STAT4,STAT5B,TNS1,LCP2,FRK,CHN1,CHN2,FGR,SHF,GRB10,SYK,FES |
| 3.476e-03 | -5.66 | GO_EMBRYO_DEVELOPMENT | MSigDB lists | GO_EMBRYO_DEVELOPMENT | 872 | 110 | 17377 | 1707 |
THOC5,ACVR1,ST14,RECK,UGDH,OTX1,RGS20,PLXNA2,GATA3,CEBPA,KIAA1217,SP8,SKI,SETDB2,EOMES,DLX6,DACT1,ITGB3,ACVR2A,ENO1,PRKACB,GLI1,FZD1,INTU,NKX3-2,WLS,YAP1,SATB2,WNT11,ACVR2B,RARRES2,ATOH1,FGFR1,SMAD3,INSIG1,PTK7,LAMB1,ITGA2,SEMA3C,DLX2,BMPR1A,DISP1,NRP1,TPM1,TANC2,APBA2,HOXB9,COBL,HEY1,PCSK5,MEF2C,LATS2,STOX2,RUNX2,CELSR1,BMPR2,FN1,SEC24D,LRP4,TJP1,OVOL2,APBA1,PHGDH,PGAP1,PPP2R3A,HOPX,EFEMP1,PDZD7,GATA2,MGAT1,FRAS1,FLRT3,TFAP2A,LRP6,DYNC2H1,SMAD6,SPRY2,DUSP1,NOS3,PCSK6,EPB41L5,VEGFC,B9D1,MICAL2,MSX1,DCHS1,RYR2,MAFB,PRICKLE1,PRDM1,ZFPM2,HOXA1,ZIC1,HEG1,DKK1,CEBPB,MMP15,ID3,FBN1,CECR2,WDR19,PCGF2,HOXD13,BMP4,SHOX2,SEMA3A,MMP16,FOXA1,DDIT3,SIX2 |
| 3.476e-03 | -5.66 | Cortactin-binding_p2_N | interpro domains | IPR019131 | 4 | 3 | 18492 | 1811 |
CTTNBP2NL,CTTNBP2,FILIP1 |
| 3.476e-03 | -5.66 | C/EBP_chordates | interpro domains | IPR016468 | 4 | 3 | 18492 | 1811 |
CEBPB,CEBPA,CEBPD |
| 3.482e-03 | -5.66 | glutathione derivative metabolic process | biological process | GO:1901685 | 22 | 7 | 17256 | 1658 |
GSTM3,GSTO1,GSTM2,GSTO2,ESD,MGST3,GSTM4 |
| 3.482e-03 | -5.66 | glutathione derivative biosynthetic process | biological process | GO:1901687 | 22 | 7 | 17256 | 1658 |
GSTM3,GSTO1,GSTM2,GSTO2,ESD,MGST3,GSTM4 |
| 3.503e-03 | -5.65 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_UP | 175 | 29 | 17377 | 1707 |
MTG1,MID2,GNG12,PFKFB2,LRP4,SYBU,ABAT,MFSD6,PFN2,HOPX,DKK1,GALNT3,SLC7A11,NCAM2,EHD3,GHR,STC2,C1orf21,RUNDC3B,KCNS3,MAP7,MARCH3,SP140,NRP1,SMAD6,DHCR7,MAST4,PKIA,ULBP1 |
| 3.503e-03 | -5.65 | ATF2_S_UP.V1_DN | MSigDB lists | ATF2_S_UP.V1_DN | 175 | 29 | 17377 | 1707 |
NDUFA4L2,MN1,MYO1D,PLSCR4,SORBS1,ENO2,KLHL3,CLGN,GALNT12,SLC39A8,CRIP2,SDC3,AK4,COBLL1,KCTD12,ROR1,SLC1A3,KBTBD11,BMP6,GAS1,EFEMP1,ID3,PDLIM3,ITGBL1,CLMN,SMAD6,IL1RAP,PNMA2,CYP1B1 |
| 3.517e-03 | -5.65 | positive regulation of lipid biosynthetic process | biological process | GO:0046889 | 66 | 14 | 17256 | 1658 |
SORBS1,PRKCD,LDLR,STARD4,SREBF1,TNFRSF1A,AGAP2,RACK1,PPARGC1A,ABHD6,SLC45A3,BMP6,ABCG1,GPLD1 |
| 3.520e-03 | -5.65 | embryonic cranial skeleton morphogenesis | biological process | GO:0048701 | 46 | 11 | 17256 | 1658 |
SMAD3,IRX5,RUNX2,WDR19,TFAP2A,DLX2,BMP4,HOXA1,MMP16,SIX2,MEF2C |
| 3.520e-03 | -5.65 | lung development | biological process | GO:0030324 | 163 | 27 | 17256 | 1658 |
ID1,CELSR1,BMPR2,YAP1,CEBPA,WNT11,ACVR2B,ZFPM2,SAV1,FGFR1,HEG1,FOXP2,RIDA,CCBE1,PTK7,SREBF1,BMP4,BMPR1A,ERRFI1,NKX2-8,DHCR7,SPRY2,FOXA1,PDGFRB,NKX2-1,GLI1,NOS3 |
| 3.530e-03 | -5.65 | MFS_1 | pfam domains | PF07690 | 65 | 14 | 17054 | 1666 |
SPNS1,SV2B,MFSD9,SLC37A1,FLVCR2,SLC22A18,SLC16A2,SLC18B1,MFSD4A,SLC16A9,SLC46A3,SLC45A3,SLC16A10,SLC43A1 |
| 3.542e-03 | -5.64 | WH1 | prosite domains | PS50229 | 11 | 5 | 12060 | 1278 |
ENAH,EVL,SPRED3,HOMER2,HOMER3 |
| 3.545e-03 | -5.64 | coenzyme metabolic process | biological process | GO:0006732 | 311 | 45 | 17256 | 1658 |
NMNAT3,MOCOS,MVK,ACSL1,ENO2,AASS,ELOVL7,SCD,NUDT12,QPRT,HMGCS1,AADAT,KMO,ALDOC,ALDH1L1,MDH1B,FAR2,PCK2,ENO1,PARP9,HMGCR,VNN2,ATP5IF1,GAPDH,PNP,PFKFB2,MVD,ALDH1L2,PANK1,ELOVL3,HACD1,FASN,OGDHL,GSTO1,TPK1,GSTO2,TDO2,PEMT,ALDOA,HK2,PGM2L1,HK1,PANK3,ACSM3,NUDT17 |
| 3.547e-03 | -5.64 | GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) | protein interactions | 2904 | 44 | 11 | 17029 | 1718 |
CAMK2N1,PRKN,KDM5B,PRKCB,LIN7A,DLG2,ARHGAP32,RACK1,PRKCA,MAGI3,PATJ |
| 3.551e-03 | -5.64 | human chr1p31.3 | chromosome location | human chr1p31.3 | 58 | 11 | 26185 | 1967 |
CACHD1,GNG12,DOCK7,LINC00466,WLS,DNAJC6,NFIA,AK4,ROR1,LEPR,PATJ |
| 3.555e-03 | -5.64 | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_UP | MSigDB lists | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_UP | 183 | 30 | 17377 | 1707 |
GPR63,CCDC126,MSX1,SH3BP2,MRC2,ALDH2,DUSP8,ZNF25,ITGA6,RYR2,TUBE1,SLC12A6,SFXN3,EXOG,SKAP1,SPIRE1,EBF1,TCF7L1,ABLIM1,CDC14B,AKAP7,KIAA0319,EBF4,DBP,NRP1,PTPRCAP,RRAS2,OSBPL6,ABCG1,GLI1 |
| 3.555e-03 | -5.64 | GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_UP | MSigDB lists | GSE2585_CD80_HIGH_VS_LOW_AIRE_KO_MTEC_UP | 183 | 30 | 17377 | 1707 |
TMC7,GPR176,BTC,MXI1,RHOQ,ACSL1,REL,ATP9A,NLRP14,NRN1,IL13RA1,ATP1B1,DNER,SCIN,SNCA,AHRR,AK1,MYADM,FLRT3,PCBP4,B3GALT2,SERINC2,SH3BP4,PAX9,MET,PLTP,FNBP1L,FKBP14,IL1RAP,DUSP1 |
| 3.555e-03 | -5.64 | GSE3982_MAST_CELL_VS_MAC_UP | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_UP | 183 | 30 | 17377 | 1707 |
PLA2G4A,MTG1,PPP1R3D,RPL26,SORBS1,ZCCHC24,SLK,RPL21,ASS1,STAT5B,GUCY1A2,KIF21B,MLC1,ABHD6,KHDRBS2,ZFYVE9,RERE,RSL24D1,CHN2,ADAMTS3,FBN1,CCNA1,RGS10,PDE4D,MAST4,HSPA2,SMYD3,ACSM3,PGBD5,DOCK9 |
| 3.555e-03 | -5.64 | GSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_DN | MSigDB lists | GSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_DN | 183 | 30 | 17377 | 1707 |
UST,MXI1,FOXN3,ZDHHC15,VIM,GPSM2,DOCK5,GALNT14,SNX9,C1orf174,TSKU,HOPX,DCBLD2,PLS3,PIK3AP1,ITGA2,RAP2A,SMTN,GRIN2D,SERPINI1,GEM,IQGAP3,ARL4D,ERRFI1,FBXO27,RRAS2,SLIT2,MMP16,FES,ULBP1 |
| 3.555e-03 | -5.64 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 183 | 30 | 17377 | 1707 |
FADS1,PDK1,TUBA1A,MPP1,ST6GAL1,CYTH3,LDLR,GABRR2,GRK6,PLEKHA1,CANX,RGS7,TLR6,SESN1,RERE,DDIT4,ISG20,ID3,ABLIM1,SLC30A4,IGF1R,RALGPS2,PRKCB,GATA2,WFS1,RGS10,MAP7,ADCY6,SQLE,RCAN3 |
| 3.555e-03 | -5.64 | GSE2585_CTEC_VS_THYMIC_MACROPHAGE_UP | MSigDB lists | GSE2585_CTEC_VS_THYMIC_MACROPHAGE_UP | 183 | 30 | 17377 | 1707 |
UNC5C,CDH26,AVPI1,GCNT2,RHOQ,ERGIC1,EIF4E3,CFH,CHCHD7,HNF4G,ALDH1L2,LPCAT2,TNFSF13B,RNF125,C3orf70,COL14A1,DOK5,SLC35F1,IRS2,REEP1,HK2,RUNDC3B,SRGAP1,ZNF808,NCAM1,ETV1,ENO1,FKBP14,KIAA1549,ULBP1 |
| 3.562e-03 | -5.64 | GO_ALCOHOL_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_ALCOHOL_BIOSYNTHETIC_PROCESS | 107 | 20 | 17377 | 1707 |
PLA2G4A,PRKAA2,MVK,LPCAT2,MVD,CYB5R2,DHCR24,ISYNA1,LPIN3,CDS1,CYP51A1,HMGCS1,IDI1,INSIG1,MSMO1,ACER2,PEMT,SQLE,DHCR7,HMGCR |
| 3.564e-03 | -5.64 | protein kinase binding | molecular function | GO:0019901 | 618 | 81 | 17224 | 1680 |
EPHA3,PRKN,RHOD,DNAJC3,PKP2,ADD2,NPM1,NTRK3,MAPK4,CTBP2,DDR1,RAC3,SKI,RND2,AKAP7,DACT1,NBEA,DAB2IP,MARCKS,EPHB6,MET,IL1RAP,PDGFRB,GAB2,ATF4,PFKFB2,ANK2,PTPN6,PRKAR2B,ATP1B1,ROR1,DSP,FGFR1,WARS,SMAD3,CAMK2N1,IRS2,NRG3,PTPRJ,GPRC5B,PRKCB,MAP3K21,DUSP19,DIRAS1,NRP1,CACUL1,FRMD5,TYRO3,SCN5A,KIZ,GRB14,RHOBTB1,LRP4,GAS6,PKN1,EPHB1,IGF1R,EEF2,PRKCD,GHR,SREBF1,ACTA2,ADCY6,ERRFI1,SPRY2,SYK,FGFR4,RHOQ,RYR2,RACK1,SKAP1,MAPKAPK2,PTPRC,TRIB3,FGR,RND3,GCSAM,MAP2K6,CDH2,SFN,PKIA |
| 3.567e-03 | -5.64 | GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_DN | 152 | 26 | 17377 | 1707 |
GPR176,SLC40A1,SLC3A2,DNM3,TMEM65,RBFOX2,ESRP1,MYO1B,SLC25A27,PLXNA2,MEI1,MAFB,SDK1,PALLD,PRKCA,PLCB1,CHD5,NEO1,ENTPD1,BACH2,PRKG1,RCN3,SHF,HGF,CDH2,NOS3 |
| 3.576e-03 | -5.63 | PLEC (plectin) | protein interactions | 5339 | 126 | 23 | 17029 | 1718 |
PDLIM7,FN1,SMAD9,TES,PLEKHA5,RAPGEF2,MLF1,ITGA6,LRRK2,NSD2,VIM,TJP1,RACK1,ATOH1,EYA4,GSDME,SKI,BAG3,MAP2,GAN,RAPGEF5,SFN,HEY1 |
| 3.582e-03 | -5.63 | JPH1 (junctophilin 1) | protein interactions | 56704 | 38 | 10 | 17029 | 1718 |
ARHGAP26,EDA,TCTN2,TNFRSF1A,KCNS3,TTC30A,SKAP1,TNFRSF19,GPR161,CHRM3 |
| 3.582e-03 | -5.63 | ACOX1 (acyl-CoA oxidase 1) | protein interactions | 51 | 38 | 10 | 17029 | 1718 |
RIDA,RAB6B,RECK,LITAF,TMED9,ATOH1,PALLD,KHDRBS2,MBNL2,RAB30 |
| 3.587e-03 | -5.63 | GO_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_KINASE_ACTIVITY | 747 | 96 | 17377 | 1707 |
NEK10,AVPI1,ACSL1,DUSP8,FGF13,DNAJC3,NPM1,CEBPA,NTRK3,LCP2,SNX9,PIBF1,PPP1R9A,PPM1E,TLR3,ZFYVE28,ITGB3,DAB2IP,MARCKS,TLR4,HSPA2,RASGRP1,PRKACB,PDGFRB,SESN2,PFKFB2,FZD4,PTPN6,TGFA,LRRK2,DEPTOR,ADCY1,PRKAR2B,WNT11,ACVR2B,CD40,FGFR1,SNCA,IRS2,CAMK2N1,RANBP2,CXCL10,NRG3,PTPRJ,GPRC5B,NCKAP1L,ERN1,WWTR1,DUSP19,TNFSF15,HGF,DIRAS1,MAPK10,LATS2,TNIK,FZD8,UBASH3B,HERC5,GAS6,PKN1,TPD52L1,IGF1R,FLRT3,GHR,PRKCD,ADCY6,LRP6,AFAP1L2,IQGAP3,ERRFI1,TNFRSF11A,SPRY2,SYK,DUSP1,HMGCR,PAK1,VAV3,MSTN,RAPGEF2,VLDLR,DUSP9,STRADB,CCNG1,TLR6,MAPKAPK2,PTPRC,TRIB3,FGR,CSF1,MAP2K6,BMP4,TESC,SMYD3,SFN,PKIA,ATP2B4 |
| 3.590e-03 | -5.63 | Pkinase_Tyr | pfam domains | PF07714 | 130 | 23 | 17054 | 1666 |
FGFR4,TYRO3,EPHA3,FER,TNK2,ACVR1C,NTRK3,ROR1,EPHB1,FRK,DDR1,FGFR1,FGR,IGF1R,PTK7,MAP3K21,BMPR1A,EPHB6,MET,MAP3K20,SYK,FES,PDGFRB |
| 3.591e-03 | -5.63 | Hippo signaling | KEGG pathways | hsa_M00683 | 16 | 6 | 7161 | 730 |
WWC1,MOB1B,YAP1,LATS2,SAV1,WWTR1 |
| 3.591e-03 | -5.63 | Hippo signaling | KEGG pathways | M00683 | 16 | 6 | 7161 | 730 |
WWC1,MOB1B,YAP1,LATS2,SAV1,WWTR1 |
| 3.594e-03 | -5.63 | GSE29618_PDC_VS_MDC_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DN | 191 | 31 | 17377 | 1707 |
PAK1,SERINC5,SH3BP2,GAPDH,EVL,TUBA1A,LGALS3,PSTPIP2,BLVRB,NDRG2,IL13RA1,CREB5,COTL1,SLCO3A1,PTPRC,RTN1,ENTPD1,FGR,GBP1,RGS10,BCL6,RAB31,HK2,SGK1,MARCKS,IPCEF1,ENO1,COL9A2,CEBPD,ATP2B1,STOM |
| 3.594e-03 | -5.63 | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_DN | MSigDB lists | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_DN | 191 | 31 | 17377 | 1707 |
FGFR4,DBN1,PCDH18,UNC5C,MARK1,ARL2,COL18A1,RASL11B,PALLD,DNER,TNFRSF19,KHDRBS2,IKZF2,NKX6-1,EPB41L3,FBXO32,TMEM150B,KCNMB4,SLC16A2,ERN1,MPP2,PRKG2,MAPK13,MARCKS,APBA2,HOXB9,MLLT3,IL9R,SFN,MAST1,CES3 |
| 3.594e-03 | -5.63 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | 191 | 31 | 17377 | 1707 |
CCDC126,PDLIM7,FARP1,PLEKHA8,SLC36A1,UBASH3B,TMEM126A,MCTP2,MGAT4B,LITAF,FASN,FHL2,TTYH2,GTF2IRD1,COBLL1,PLS1,ISYNA1,FAM174B,MCOLN2,SLC7A1,SETDB2,GYPC,RAB31,SVIL,SLC22A15,CERS4,IPCEF1,ARL4D,SPRY2,FES,C3orf67 |
| 3.594e-03 | -5.63 | GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN | MSigDB lists | GSE28783_ANTI_MIR33_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_DN | 191 | 31 | 17377 | 1707 |
QSOX1,FARP1,RHOQ,DYRK3,PTPN13,SLC39A8,UGDH,SELL,KCTD12,SCD,TMEM47,GUCY1A2,LCP2,PALLD,ATP10D,PPP2R3A,CHST10,DKK1,EPB41L3,TLR3,BNIP1,RPL28,AFF2,KCNS3,PRKG1,MAP7,BMPR1A,CPE,ZNF460,RASGRP1,PCSK5 |
| 3.594e-03 | -5.63 | GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_DN | MSigDB lists | GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_DN | 191 | 31 | 17377 | 1707 |
BCL11B,SSH3,NR4A1,SYT12,AGPAT4,EFHC2,GATA3,RASA3,NDRG2,MARS,SLC12A6,COLEC10,HERC6,ZNF219,DDR1,SATB1,LGI2,SLC7A1,CAMK2N1,KCNMB4,RALGPS2,MCF2L,ITGB3,ADCY6,TUFT1,FAM84B,ALPK1,TNFSF4,PURG,RBMS2,LPP |
| 3.594e-03 | -5.63 | TACTTGA,MIR-26A,MIR-26B | MSigDB lists | TACTTGA,MIR-26A,MIR-26B | 288 | 43 | 17377 | 1707 |
PCDH18,MXI1,CELSR1,LGR4,ZCCHC24,LSM11,PSD3,ADAMTS6,CHAC1,NDFIP2,RTN1,EPB41L3,RPS6KA2,SLC7A11,ZDHHC6,PRKCD,SRGAP1,POF1B,COL19A1,JAKMIP2,NCEH1,BOD1,INTU,PHLDB2,MARK1,PNRC1,ACVR1C,PTPN13,VLDLR,STRADB,CTTNBP2NL,PLCB1,NAP1L5,MAP2,PLOD2,PELI2,HPGD,HGF,TBC1D4,TRPC3,MMP16,LARP1,CTNND2 |
| 3.604e-03 | -5.63 | V$HNF1_Q6 | MSigDB lists | V$HNF1_Q6 | 239 | 37 | 17377 | 1707 |
CHCHD7,PLAG1,COL4A5,FAM117B,ZIC2,CREB5,FOXG1,FOXP2,ZNF827,PPFIBP1,SAMD11,GAN,ACVR2A,PDE4D,PPP2R2B,ERRFI1,ESD,MED12L,FGFR4,PRICKLE1,SATB2,PRDM1,CTTNBP2NL,ZFPM2,SGK2,MBNL2,BCL11A,HTR7,SLC39A14,RASGRF2,CDH17,SLCO5A1,PPARGC1A,NRP1,SEMA3A,HOXB9,LPP |
| 3.604e-03 | -5.63 | V$FOXO4_02 | MSigDB lists | V$FOXO4_02 | 239 | 37 | 17377 | 1707 |
CXCR5,PCDH18,CHCHD7,PLAG1,RASD1,NTRK3,LCP2,IKZF2,KREMEN1,HMCN1,ZFYVE9,NEDD4,FOXP2,ZNF827,ZNF362,FRY,SLC10A7,ZNF521,GFRA1,SCN3A,BDNF,BCL7A,MEIS2,FGF12,SATB2,PRDM1,SKAP1,EML1,NAP1L5,KLF12,GNAO1,PLXDC2,TIGD4,KLF5,TNFSF4,MAPK10,CACNA2D1 |
| 3.616e-03 | -5.62 | MFS | interpro domains | IPR011701 | 65 | 14 | 18492 | 1811 |
SPNS1,SV2B,MFSD9,SLC37A1,FLVCR2,SLC22A18,SLC16A2,SLC18B1,MFSD4A,SLC16A9,SLC46A3,SLC45A3,SLC16A10,SLC43A1 |
| 3.616e-03 | -5.62 | nucleotide catabolic process | biological process | GO:0009166 | 102 | 19 | 17256 | 1658 |
NUDT10,GAPDH,PDE1B,PNP,ENO2,PFKFB2,OGDHL,PDE8A,NUDT12,PRTFDC1,PDE10A,ALDOC,ALDOA,HK2,PGM2L1,PDE4D,HK1,ENO1,NUDT17 |
| 3.616e-03 | -5.62 | human chr4q32.3 | chromosome location | human chr4q32.3 | 21 | 6 | 26185 | 1967 |
PALLD,MSMO1,CPE,APELA,DDX60L,SPOCK3 |
| 3.619e-03 | -5.62 | PERK-mediated unfolded protein response | biological process | GO:0036499 | 12 | 5 | 17256 | 1658 |
ATF3,ASNS,ATF4,HERPUD1,DDIT3 |
| 3.619e-03 | -5.62 | regulation of GTP binding | biological process | GO:1904424 | 12 | 5 | 17256 | 1658 |
ARHGAP28,RIPOR2,MET,CLN5,GPSM1 |
| 3.619e-03 | -5.62 | actin crosslink formation | biological process | GO:0051764 | 12 | 5 | 17256 | 1658 |
PLS1,MARCKS,EPS8,BAIAP2,PLS3 |
| 3.619e-03 | -5.62 | intracellular cholesterol transport | biological process | GO:0032367 | 12 | 5 | 17256 | 1658 |
LRP6,NPC2,LDLR,STARD4,ABCG1 |
| 3.621e-03 | -5.62 | REACTOME_NCAM1_INTERACTIONS | MSigDB lists | REACTOME_NCAM1_INTERACTIONS | 39 | 10 | 17377 | 1707 |
COL9A3,COL6A2,COL4A3,COL4A4,CACNB2,COL4A5,NCAM1,CACNB4,COL9A2,GFRA1 |
| 3.621e-03 | -5.62 | GO_NEGATIVE_CHEMOTAXIS | MSigDB lists | GO_NEGATIVE_CHEMOTAXIS | 39 | 10 | 17377 | 1707 |
SEMA6B,NRG3,SEMA4F,FLRT3,ITGB3,SEMA3C,SEMA3A,SLIT2,SEMA6A,SEMA6C |
| 3.621e-03 | -5.62 | GO_REGULATION_OF_AXON_GUIDANCE | MSigDB lists | GO_REGULATION_OF_AXON_GUIDANCE | 39 | 10 | 17377 | 1707 |
SEMA6B,SEMA4F,BMPR2,PLXNA2,SEMA3C,NRP1,SEMA3A,SLIT2,SEMA6A,SEMA6C |
| 3.621e-03 | -5.62 | GO_PROTEIN_SERINE_THREONINE_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_SERINE_THREONINE_TYROSINE_KINASE_ACTIVITY | 39 | 10 | 17377 | 1707 |
PRKAA2,DYRK1B,TNK2,DYRK3,RPS6KA2,MAP2K6,LRRK2,SGK1,ACVR2B,MAPK10 |
| 3.628e-03 | -5.62 | GO_REGULATION_OF_SECRETION | MSigDB lists | GO_REGULATION_OF_SECRETION | 676 | 88 | 17377 | 1707 |
EXPH5,DOC2A,LGR4,TRIM16,SYT12,VAMP8,GATA3,LILRB1,ITPR2,ABAT,SYT14,NRXN1,PRKCA,PCLO,PPP1R9A,NCS1,SCIN,UNC13B,RAB26,KCNS3,MARCKS,RAB27B,TLR4,MYRIP,RASGRP1,GAB2,FER,CSN2,ACVR1C,PFKFB2,WLS,LRRK2,CHRNA6,PRKCQ,CD40,SERGEF,SNCA,IRS2,TRIM9,KCNMB4,GBP1,PAM,OXTR,ATG5,TNFSF4,SEPT5,TC2N,MEF2C,C1QTNF3,FN1,STXBP5L,CD276,STXBP6,APBB1,ARL2,P2RY1,GAS6,KCNC4,PFN2,BMP6,MCU,NKX6-1,RAB11FIP5,SREBF1,SGK1,CADPS2,MYO6,STXBP1,TNFRSF11A,SYK,RIMS2,FES,HMGCR,TRPM4,VEGFC,RAB3B,KDM5B,CACNA1E,SYBU,RAPGEF4,SNAP25,PLCB1,TLR6,GPLD1,FGR,ICA1,MAP2K6,XBP1 |
| 3.628e-03 | -5.62 | GO_SENSORY_ORGAN_DEVELOPMENT | MSigDB lists | GO_SENSORY_ORGAN_DEVELOPMENT | 483 | 66 | 17377 | 1707 |
MCOLN3,OTX1,GATA3,CEBPA,NTRK3,DDR1,SKI,PLS3,DLX6,CHRDL1,LIN7A,MYH15,PDGFRB,CYP1B1,GPM6A,MEIS2,FZD4,NKX3-2,VIM,ACVR2B,ATOH1,FGFR1,TSKU,SMAD3,INSIG1,PTK7,ATG5,NRP1,BCL11B,BMPR2,CELSR1,GABRB2,LAMC3,EPHB1,BMP6,PPP2R3A,FOXP2,EFEMP1,SLC7A11,GATA2,PDZD7,TFAP2A,LRP6,TSPAN12,SH3PXD2B,SPRY2,ATP2B1,B9D1,RAX,MSX1,KDM5B,DCHS1,MAFB,SMARCD3,SDK1,PRDM1,HOXA1,ZIC1,MAPKAPK2,FAT4,FBN1,WDR19,BMP4,NPHP1,ATP2B4,SIX2 |
| 3.633e-03 | -5.62 | AIGNER_ZEB1_TARGETS | MSigDB lists | AIGNER_ZEB1_TARGETS | 33 | 9 | 17377 | 1707 |
EPCAM,PMEPA1,TSPAN15,MARVELD2,GJB2,DSP,OCLN,SFN,PCDH7 |
| 3.633e-03 | -5.62 | PETRETTO_CARDIAC_HYPERTROPHY | MSigDB lists | PETRETTO_CARDIAC_HYPERTROPHY | 33 | 9 | 17377 | 1707 |
EFEMP1,FN1,PDLIM3,CRIM1,FBN1,ARID5B,ACTA2,ABAT,IGFBP3 |
| 3.633e-03 | -5.62 | Phase 0 - rapid depolarisation | REACTOME pathways | R-HSA-5576892 | 47 | 11 | 10287 | 971 |
SCN5A,CACNG3,FGF13,SCN1B,CACNB2,SCN8A,FGF12,SCN2A,CACNB4,CACNA2D1,SCN3A |
| 3.647e-03 | -5.61 | V$PR_01 | MSigDB lists | V$PR_01 | 137 | 24 | 17377 | 1707 |
TYRO3,CCDC126,BDNF,MSTN,CHCHD7,KCNH5,DSTN,PLAG1,ITGA6,JPH1,AGAP2,FGF17,ARHGAP32,IKZF2,FSTL5,TUBB4A,NSD1,TMEM86A,BCL6,ADCY6,DLG2,FIGN,RAB30,FES |
| 3.647e-03 | -5.61 | GCM_PTK2 | MSigDB lists | GCM_PTK2 | 137 | 24 | 17377 | 1707 |
FADS1,ARHGAP26,PTPRD,MYO10,AGPAT4,BACE1,DNAJC6,ZNF565,TTYH2,KIF5C,PLEKHA1,ABHD6,NCS1,PLEKHB1,SPIRE1,ARHGAP21,EPB41L3,GPRC5B,DIRAS1,TMOD2,KIF1B,FMNL2,BTRC,DOCK9 |
| 3.655e-03 | -5.61 | GO_GROWTH_FACTOR_BINDING | MSigDB lists | GO_GROWTH_FACTOR_BINDING | 122 | 22 | 17377 | 1707 |
FGFR4,SCN5A,ACVR1,IGFBP6,BMPR2,TRIM16,WISP3,ACVR1C,CRIM1,NTRK3,ACVR2B,FGFR1,TGFBR3,IGF1R,GHR,ACVR2A,NRP1,LIFR,PDGFRB,DUSP1,IGFBP3,PCSK6 |
| 3.662e-03 | -5.61 | hindbrain development | biological process | GO:0030902 | 140 | 24 | 17256 | 1658 |
PAK1,SCN5A,SMAD9,FZD4,RBFOX2,WLS,OTX1,OPHN1,PLXNA2,NLGN4X,MAFB,ABAT,AARS,CBLN1,CTNNA2,RERE,FOXP2,GATA2,PTPRS,LRP6,PPARGC1A,ZNF365,GLI1,CNTN1 |
| 3.662e-03 | -5.61 | cellular response to starvation | biological process | GO:0009267 | 140 | 24 | 17256 | 1658 |
PRKAA2,FADS1,SESN2,ATF4,BMPR2,LRRK2,NUAK2,MARS,ATF3,GAS6,SESN1,STK24,GABARAPL1,ASNS,PMAIP1,BHLHA15,CTSV,XBP1,SREBF1,CADPS2,PIK3C2B,ATG5,RRAGD,RNF152 |
| 3.674e-03 | -5.61 | TGCAAAC,MIR-452 | MSigDB lists | TGCAAAC,MIR-452 | 100 | 19 | 17377 | 1707 |
DOC2A,ATL1,SCN8A,TMEM47,SAV1,EPHB1,SP8,ZIC1,TRPS1,TBC1D19,AKT3,AFF2,CACNB2,RAI14,IQSEC2,MMP16,KIF1B,DOCK9,PHC1 |
| 3.682e-03 | -5.60 | thalamus | COSMIC cancer mutations | thalamus | 290 | 43 | 17385 | 1698 |
MYO1D,STOX2,ACVR1,UGDH,XYLT1,PLXNA2,TDRKH,SPINK5,SEL1L3,PPP2R3A,SPEG,PDE10A,PPFIA2,KAZN,MET,KIAA1549,SLIT2,POU3F3,PNMA2,TRPM4,MN1,GARS,TBC1D8B,JPH1,PACSIN3,PYGO1,CCNG1,ZBBX,OR11H4,FGFR1,CTIF,GNAI1,AHRR,EBF1,TMCO3,TIFA,PCDHB7,NACC2,ITGA2,LAMB1,RNF130,COBL,PCSK5 |
| 3.696e-03 | -5.60 | YAGI_AML_WITH_11Q23_REARRANGED | MSigDB lists | YAGI_AML_WITH_11Q23_REARRANGED | 330 | 48 | 17377 | 1707 |
CARS,DMXL2,THOC5,ALOX5AP,GRIK2,OVOL2,ITPR2,KBTBD11,SEL1L3,CDR2L,LIN7A,MYO6,GFRA1,GPM6A,COL6A2,SLC27A2,SLC36A1,MCF2L2,LRMP,HIP1,FEZ1,AK4,PRKCQ,PLS1,RARRES2,ATP1B1,EXOG,CLN5,SMPDL3B,WARS,GNAI1,CTIF,DEXI,ENTPD1,SLC7A1,RANBP2,ATPAF2,PLAGL1,GYPC,PRKCB,WFS1,XBP1,RGS10,SEMA3C,DHCR7,NKX2-8,IL9R,MEF2C |
| 3.698e-03 | -5.60 | DLK1 (delta like non-canonical Notch ligand 1) | protein interactions | 8788 | 70 | 15 | 17029 | 1718 |
SCAMP1,TCAF2,SLC16A2,LAPTM4B,EGFL7,STEAP3,ACVR2B,FNDC3A,SLC19A2,FGFR1,GAS1,MYORG,OCLN,ATP2B4,ATP1A3 |
| 3.703e-03 | -5.60 | GABRIELY_MIR21_TARGETS | MSigDB lists | GABRIELY_MIR21_TARGETS | 272 | 41 | 17377 | 1707 |
MYCBP2,TRIM2,BMPR2,RECK,ST6GAL1,CYP4V2,FAM102B,COBLL1,ENAH,ZBTB38,RALGPS2,NBEA,SCRN1,PRICKLE2,MPDZ,LIMCH1,WWC2,FIGN,TLR4,RASGRP1,TMEM56,PARP9,KLHL3,FOXN3,JPH1,FERMT2,PHACTR2,CCNG1,PALLD,SESN1,SFXN1,ARHGAP21,DDAH1,RAI14,KLF5,ZBTB20,PLD1,VASH2,TPM1,LIFR,ATP2B4 |
| 3.706e-03 | -5.60 | Znf_LIM | interpro domains | IPR001781 | 72 | 15 | 18492 | 1811 |
PDLIM7,ABLIM1,MICAL2,PXN,PDLIM3,TES,CRIP2,LHX6,LMCD1,FHL2,PRICKLE1,PRICKLE2,LIMCH1,CSRP2,LPP |
| 3.713e-03 | -5.60 | GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 65 | 14 | 17377 | 1707 |
GSTM2,CACNB2,ANK2,JPH1,RYR2,GSTO1,BMP4,PDE4D,ATP1B1,CACNB4,ASPH,HSPA2,NOS1AP,CACNA2D1 |
| 3.713e-03 | -5.60 | GO_IRON_ION_HOMEOSTASIS | MSigDB lists | GO_IRON_ION_HOMEOSTASIS | 65 | 14 | 17377 | 1707 |
SFXN1,SLC40A1,SLC22A17,SFXN4,MYC,BDH2,ACO1,BTBD9,SLC25A28,STEAP3,SFXN3,BMP6,STEAP1,NEO1 |
| 3.741e-03 | -5.59 | ankle | COSMIC cancer mutations | ankle | 400 | 56 | 17385 | 1698 |
EXPH5,TCP11L2,STXBP5L,PTPRD,KIF5A,ELOVL7,PTPN21,ARHGAP22,GTF2IRD1,ZNF215,CADM2,COL14A1,SLCO3A1,PPP2R3A,FHOD3,NELL2,NUMBL,JAKMIP2,FIG4,VWA5A,PTPRE,TSHR,KCNB2,RIMS2,CHRM3,INTU,PHLDB2,ALDH2,GSTM2,COL4A3,DCC,FZD4,COL4A4,PTPN13,FERMT2,TNS1,ARHGAP32,GUCY1A2,PLCB1,PTPRC,TMCO3,NRG3,IQCH,PTPRJ,PKN3,ADAMTS3,MAP2,L3MBTL4,PTPRS,PGM2L1,PTPRN2,NEK11,ARHGAP28,OSBPL6,SMYD3,MAST1 |
| 3.746e-03 | -5.59 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | 168 | 28 | 17377 | 1707 |
TRIM2,BMPR2,CLGN,SLC36A1,ST6GAL1,APBB1,HOMER2,MCOLN3,FHL2,NPC2,SLC12A6,PFN2,STEAP1,NAP1L5,SLC39A14,EPB41L3,ENPP1,TGFBR3,HPSE,PLK2,TSC22D1,RALGAPA2,SFMBT1,ACVR2A,NAP1L3,INPP5F,MBOAT2,KIF1B |
| 3.750e-03 | -5.59 | cell surface receptor signaling pathway involved in cell-cell signaling | biological process | GO:1905114 | 424 | 58 | 17256 | 1658 |
PRKAA2,TNIK,AMOTL1,LGR4,CELSR1,CELSR3,GRIK2,FZD8,LRP4,GATA3,NDRG2,NOTUM,GRK6,KREMEN1,PPP1R9A,CHRNA5,DACT1,MYC,LRP6,PRICKLE2,CPE,SNAI2,GLI1,FZD1,DISC1,MARK1,PTPRU,FZD4,WLS,LRRK2,GRID1,PRICKLE1,FERMT2,RYR2,CHRNA6,AGO4,WNT11,PYGO1,ROR1,PLCB1,GPC6,DKK1,SNCA,SMAD3,GRIK4,TCF7L1,PTK7,GNAO1,MPP2,MCC,GRIN2D,BMP4,MAGI2,HOXB9,BTRC,CTNND2,DDIT3,MEF2C |
| 3.760e-03 | -5.58 | oligosaccharide biosynthetic process | biological process | GO:0009312 | 40 | 10 | 17256 | 1658 |
GALNT3,GALNT1,B3GALT1,GALNT12,GALNT6,B3GALT2,GALNT17,GALNT13,GALNT18,GALNT14 |
| 3.760e-03 | -5.58 | regulation of cardiac muscle cell contraction | biological process | GO:0086004 | 40 | 10 | 17256 | 1658 |
TRPM4,RYR2,PKP2,SCN5A,PDE4D,FGF13,DSP,ANK2,DSG2,NOS1AP |
| 3.764e-03 | -5.58 | CAHOY_OLIGODENDROCUTIC | MSigDB lists | CAHOY_OLIGODENDROCUTIC | 93 | 18 | 17377 | 1707 |
SERINC5,UGT8,CLYBL,PSTPIP2,BACE1,CRIP2,PRKCQ,RBM11,CDR2L,SPEG,KIAA1958,DOCK7,P4HA2,DUSP19,NRP1,FIGN,RNF122,KCTD1 |
| 3.768e-03 | -5.58 | glycoprotein biosynthetic process | biological process | GO:0009101 | 312 | 45 | 17256 | 1658 |
CCDC126,UST,GXYLT2,BMPR2,GALNT12,GALNT6,ST6GAL1,XYLT1,ALG1L,GALNT13,CHSY1,MGAT5B,BCAN,GBGT1,GALNT1,MGAT1,FUT9,HS3ST5,COG3,ST8SIA1,GALNT18,ALG10B,B4GALT6,CHSY3,B3GALT1,B3GLCT,GCNT2,MVD,MGAT4B,EDEM3,ST6GALNAC3,GALNT17,PXYLP1,GALNT14,GLCE,DPY19L2,GALNT3,PLOD2,SRD5A3,B3GALT2,ALG11,DSEL,HS3ST3B1,B4GALT7,HS6ST3 |
| 3.771e-03 | -5.58 | human chr13q32.2 | chromosome location | human chr13q32.2 | 5 | 3 | 26185 | 1967 |
FARP1,IPO5,STK24 |
| 3.773e-03 | -5.58 | human chr8q24.12 | chromosome location | human chr8q24.12 | 15 | 5 | 26185 | 1967 |
SNTB1,COLEC10,COL14A1,SAMD12-AS1,DEPTOR |
| 3.773e-03 | -5.58 | human chr10q21.2 | chromosome location | human chr10q21.2 | 15 | 5 | 26185 | 1967 |
RTKN2,SLC16A9,RHOBTB1,ZNF365,ARID5B |
| 3.787e-03 | -5.58 | YTAAYNGCT_UNKNOWN | MSigDB lists | YTAAYNGCT_UNKNOWN | 145 | 25 | 17377 | 1707 |
NDUFA4L2,TYRO3,MEIS2,ACVR1C,NR6A1,PRDM13,VLDLR,OTX1,GATA3,WWC1,ATF3,FGF17,ZFPM2,NRXN1,PELI2,FLRT3,SAMD11,EIF1,CHRDL1,HRK,DBP,PPP2R2B,PPARGC1A,FNBP1L,CTNND2 |
| 3.787e-03 | -5.58 | LIN_NPAS4_TARGETS_UP | MSigDB lists | LIN_NPAS4_TARGETS_UP | 145 | 25 | 17377 | 1707 |
PFKFB4,PRKAA2,RAB3B,GABRB2,ALDH1L2,ST6GAL1,DHCR24,ADD2,NTRK3,CCNG1,C3orf70,MFSD6,FAM81A,TMEM74,MOK,AKT3,RASGRF2,KIAA0319,FAM107B,SGK1,MLLT3,SCN3A,PKIA,PNMA2,RNF152 |
| 3.791e-03 | -5.58 | FFAR2 (free fatty acid receptor 2) | protein interactions | 2867 | 4 | 3 | 17029 | 1718 |
IGF1R,GNAO1,CYB5R2 |
| 3.791e-03 | -5.58 | DPP10 (dipeptidyl peptidase like 10) | protein interactions | 57628 | 4 | 3 | 17029 | 1718 |
DPP10,BAG3,KCND3 |
| 3.791e-03 | -5.58 | BMP10 (bone morphogenetic protein 10) | protein interactions | 27302 | 4 | 3 | 17029 | 1718 |
ACVR2A,ACVR2B,BMPR2 |
| 3.791e-03 | -5.58 | Tubb4b (tubulin, beta 4B class IVb) | protein interactions | 296554 | 4 | 3 | 17029 | 1718 |
PRICKLE1,PRICKLE2,STXBP5L |
| 3.791e-03 | -5.58 | Capza2 (capping protein (actin filament) muscle Z-line, alpha 2) | protein interactions | 12343 | 4 | 3 | 17029 | 1718 |
ABCG1,SNCA,HACE1 |
| 3.793e-03 | -5.57 | GNAO1 (G protein subunit alpha o1) | protein interactions | 2775 | 57 | 13 | 17029 | 1718 |
BAG3,RGS16,SLC30A4,PTPRU,KLHL3,SCN8A,GNAO1,RGS10,RGS20,GPSM2,RGS7,TSHR,GNAI1 |
| 3.800e-03 | -5.57 | endocardial cushion formation | biological process | GO:0003272 | 17 | 6 | 17256 | 1658 |
MSX1,BMPR1A,BMP4,HEYL,DCHS1,SNAI2 |
| 3.800e-03 | -5.57 | membrane depolarization during cardiac muscle cell action potential | biological process | GO:0086012 | 17 | 6 | 17256 | 1658 |
TRPM4,SCN5A,SCN1B,CACNB2,ANK2,CACNA2D1 |
| 3.800e-03 | -5.57 | postsynapse assembly | biological process | GO:0099068 | 17 | 6 | 17256 | 1658 |
NLGN4X,NRXN1,MAGI2,CDH2,LRP4,SHANK2 |
| 3.810e-03 | -5.57 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | 176 | 29 | 17377 | 1707 |
IL15,ARHGEF11,HERC5,BCL6B,AGAP2,GPR180,SEZ6L2,HERC6,SLCO3A1,HPCAL4,ZNF618,DDX60L,WARS,DDIT4,ISG20,CXCL10,GRHL1,PMAIP1,GBP1,NCOA7,HK2,PTPRS,SP140,ERRFI1,CMPK2,SLFN5,DDIT3,SP140L,PARP9 |
| 3.810e-03 | -5.57 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_DN | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_DN | 176 | 29 | 17377 | 1707 |
NMNAT3,AVPI1,ZNF395,MPP1,BACE1,BLVRB,GDPD1,DEPTOR,TNFSF13B,SORBS3,AIG1,FAM13A,PLCB1,MBNL2,PRRG4,HERPUD1,SPATA7,TPK1,CHN2,KCNMB4,CPVL,FMO4,GAS2L3,PAM,HGF,RNF130,DIRC2,CEBPD,MEF2C |
| 3.810e-03 | -5.57 | GO_REGULATION_OF_DENDRITE_MORPHOGENESIS | MSigDB lists | GO_REGULATION_OF_DENDRITE_MORPHOGENESIS | 72 | 15 | 17377 | 1707 |
TNIK,NUMBL,DNM3,ID1,PTPRD,AKAP5,RAPGEF2,LRRK2,RAP2A,SGK1,MARCKS,LZTS1,PPP1R9A,NEDD4,BAIAP2 |
| 3.810e-03 | -5.57 | GO_ACTIVATION_OF_GTPASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_GTPASE_ACTIVITY | 72 | 15 | 17377 | 1707 |
ADPRHL1,DOCK7,TBC1D8B,TBC1D1,GPR65,RALGAPA2,NTRK3,TBC1D9,TBC1D4,TBC1D16,TBC1D30,RASGRP1,SYDE2,TBC1D2,TBC1D8 |
| 3.810e-03 | -5.57 | GO_CELL_CELL_JUNCTION_ASSEMBLY | MSigDB lists | GO_CELL_CELL_JUNCTION_ASSEMBLY | 72 | 15 | 17377 | 1707 |
EPB41L3,UGT8,MPP7,ANK2,MARVELD2,GJB2,PKP2,ARL2,WNT11,TJP1,TLN2,PRKCA,OCLN,GJC1,HEG1 |
| 3.823e-03 | -5.57 | SANA_TNF_SIGNALING_DN | MSigDB lists | SANA_TNF_SIGNALING_DN | 86 | 17 | 17377 | 1707 |
EFEMP1,ITGA6,CCNA1,CRIP2,AHNAK2,ZNF521,FHL2,CALCRL,KCTD12,FAM198B,DDR1,PRKACB,MTUS1,TXNDC5,TPT1,NOS3,GLCE |
| 3.823e-03 | -5.57 | HILLION_HMGA1B_TARGETS | MSigDB lists | HILLION_HMGA1B_TARGETS | 86 | 17 | 17377 | 1707 |
EPHA3,FGFR4,ID3,CXCL10,GSTM2,ID1,RPL12,DCC,RPS11,RPL21,CRIP2,TNFRSF1A,SDC3,HRK,RPS12,UNC5B,NOS3 |
| 3.823e-03 | -5.57 | V$LXR_DR4_Q3 | MSigDB lists | V$LXR_DR4_Q3 | 86 | 17 | 17377 | 1707 |
PODXL2,RNF145,PLAG1,BLVRB,OTX1,MAFB,IKZF2,HPCAL4,FOXP2,NELL2,PTK7,SGK1,FAM155B,LRP3,FRMD5,MEF2C,ABCG1 |
| 3.835e-03 | -5.56 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | 248 | 38 | 17377 | 1707 |
AVPI1,DNM3,CCDC148,ZNF395,LDLR,MCTP2,NDRG2,GPR180,CEBPA,USP30,KIAA1217,NUDT12,KREMEN1,TTC30B,CDS1,ZNF362,FBXO32,SETDB2,CACNB2,EHD3,REEP1,COL19A1,VGLL4,DNAH5,SPRY2,SUSD3,RIN2,USP2,KLHL23,LRMP,ZNF605,PRICKLE1,CCDC85A,TLR6,HOXA1,STEAP1,SMPDL3B,VASH2 |
| 3.850e-03 | -5.56 | BBC | smart domains | SM00502 | 15 | 6 | 9493 | 1056 |
TRIM3,FSD1,TRIM9,MID2,TRIM2,MID1 |
| 3.853e-03 | -5.56 | ZYX (zyxin) | protein interactions | 7791 | 105 | 20 | 17029 | 1718 |
LATS2,VAV3,GARS,EVL,PXN,FN1,TES,YAP1,FERMT2,NPM1,ENAH,VIM,ATOH1,UCHL3,TUFT1,LIN7A,ACTA2,TANC2,TPM1,FOXA1 |
| 3.857e-03 | -5.56 | divalent inorganic cation transport | biological process | GO:0072511 | 287 | 42 | 17256 | 1658 |
CACNG3,MCOLN3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,SLC30A4,CACNB2,BHLHA15,TRPC1,CNNM2,TMEM37,NIPAL2,FAM155B,FAM155A,ATP2B1,TRPM4,SLC40A1,GPM6A,SLC3A2,CSN2,SLC39A8,ANK2,CACNA1E,JPH1,CALCRL,RASA3,RYR2,ABCC2,SLC39A14,PTPRC,CACHD1,ASIC1,GRIN2D,TRPC3,CACNA2D1,ATP2B4,DDIT3,TPT1,DENND5B |
| 3.859e-03 | -5.56 | GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 184 | 30 | 17377 | 1707 |
DPYSL5,VAV3,GPM6A,MYO10,DCC,GALNT6,DNAJC3,SCD,WNT11,RAB38,TAF4B,NUDT12,ATP10D,METAP1D,NEGR1,HOMER3,PTPRC,TM9SF2,PIK3AP1,FUT9,ALDOC,SLC2A12,BEND4,TOX,FBXL2,SNX10,MYRIP,LIFR,FMNL2,HMGCR |
| 3.859e-03 | -5.56 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | 184 | 30 | 17377 | 1707 |
EML5,PDK1,TUBA1A,MPP1,ST6GAL1,CYTH3,LDLR,GABRR2,PLEKHA1,GRK6,RGS7,CANX,TLR6,BBS9,SESN1,DDIT4,ISG20,ID3,ABLIM1,RPS6KA2,IGF1R,RALGPS2,SLC30A4,PRKCB,WFS1,MAP7,P4HA1,ADCY6,LAPTM4B,SQLE |
| 3.859e-03 | -5.56 | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | 184 | 30 | 17377 | 1707 |
LATS2,PHLDB2,ITPRIP,PLEKHA5,MPP1,STAT4,CYTH3,AGAP2,ZNF219,LCP2,MBNL2,ATP10D,FKBP11,HEG1,FAM131B,MAPKAPK2,GALNT3,CAMK2N1,KCNAB1,FCHO2,PIK3AP1,ZFYVE28,ABI3,TNFRSF1A,ZNF474,SP140,BMPR1A,GFI1,PTPRE,DCBLD1 |
| 3.859e-03 | -5.56 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_UP | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_UP | 184 | 30 | 17377 | 1707 |
PAK1,LONRF1,QSOX1,INPPL1,SLC3A2,UGT8,HEBP1,ATP8A1,LSM11,GAS6,C3orf70,TGDS,NDFIP2,TLR6,COL14A1,ATP10D,PLS3,SNCA,FKBP9,TIFA,PLAGL1,QPCTL,INPP4B,RCN3,MARCKS,BMPR1A,RCAN3,FBXL2,ZFP36L2,CEBPD |
| 3.859e-03 | -5.56 | GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_MARGINAL_ZONE_BCELL_UP | 184 | 30 | 17377 | 1707 |
TMEM132C,MRC2,CACNG3,RASAL2,BMPR2,RNF144A,ARL15,ATF7IP2,CHSY1,SDK1,CD7,SPINK5,DDR1,AHRR,SETDB2,SLC30A4,AKAP7,ADCK1,GPR155,GRIN2D,ZNF808,TSPAN13,SERPINH1,SCN2A,CMPK2,DNAH5,BTRC,CACNA2D1,FRMD5,MEF2C |
| 3.872e-03 | -5.55 | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | 356 | 51 | 17377 | 1707 |
CREB3L2,CGN,RGS16,ACSL1,IL32,ENO2,FLVCR2,CELSR3,BLVRB,SELL,NDRG2,COL18A1,ENAH,CEBPA,SLC36A4,STAT5B,SLC1A3,KIF21B,HMGCS1,CA2,MAP1A,PIK3AP1,ABI3BP,MGAT1,KLF9,TNFRSF11A,PDGFRB,PCSK6,ITGB7,TNK2,GSTM2,TUBA1A,SH2D2A,NR4A1,GSTM4,SPATA13,PREX1,HIP1,B4GALNT3,PYCR1,EBF1,INSIG1,HEYL,XBP1,RGS10,RAI14,SFMBT1,SQLE,PIK3C2B,GEM,TTC39A |
| 3.880e-03 | -5.55 | human chr6q22.31 | chromosome location | human chr6q22.31 | 28 | 7 | 26185 | 1967 |
NKAIN2,RNF217,CLVS2,TPD52L1,SMPDL3A,CEP85L,TBC1D32 |
| 3.881e-03 | -5.55 | Guanylate_kin-like_dom | interpro domains | IPR008144 | 22 | 7 | 18492 | 1811 |
DLG2,TJP1,MPP7,MAGI2,MPP1,MAGI3,MPP2 |
| 3.888e-03 | -5.55 | nucleotide binding | molecular function | GO:0000166 | 2092 | 239 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,UGDH,TUBE1,ASS1,CTBP2,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,BAG3,RPS6KA2,KCNAB1,AKAP7,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,FAM114A2,ATP7B,ERN1,BDH2,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,CRYL1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,DHCR24,RIMKLA,RASL11B,GPSM2,PHGDH,ADSSL1,CHD5,GRPEL2,HSPA12B,ZBTB38,PRTFDC1,EEF2,IGF1R,ADCK1,ABCA5,APLF,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,NOS3,HMGCR,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,FASN,STRADB,OBSCN,CDC42BPA,LDHD,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SQLE,DHCR7,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,CHUK,MAPK4,NTRK3,GRK6,KIF21B,DDR1,DDX60L,TXNRD3,SPEG,ASNS,KMO,RPS6KL1,MYO3B,ACVR2A,MYH15,FHIT,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GAPDH,GARS,TUBA1A,PDK1,PFKFB2,MVD,CYB5R2,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,HPGD,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PARP9,PFKFB4,TRPM4,MICAL2,OPLAH,RAB3B,ALDH2,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,FMO4,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 |
| 3.893e-03 | -5.55 | ZU5 | pfam domains | PF00791 | 12 | 5 | 17054 | 1666 |
UNC5C,TJP1,UNC5B,ANK2,SH3BP4 |
| 3.893e-03 | -5.55 | GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_UP | 192 | 31 | 17377 | 1707 |
CXCR5,FER,DNM3,SLC6A9,ENO2,ATP9A,TGFA,BLVRB,PPFIBP2,WWC1,GATA3,SDC3,HERC5,NDRG2,TJP1,COTL1,PALLD,MBNL2,GLCE,GNAI1,SLC39A14,IKZF3,NACC2,TSC22D1,KIAA0513,SGK1,GRB10,SHOX2,TNFRSF11A,ATP2B4,IGSF3 |
| 3.893e-03 | -5.55 | GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 192 | 31 | 17377 | 1707 |
LPAR2,RUNX2,BTNL9,ADM2,JDP2,SCN8A,DNAJC6,PPFIBP2,GPSM1,COBLL1,PSD3,KCTD12,WDFY4,SCIN,CDS1,BCL11A,EPB41L3,ARHGAP21,DOCK7,HK2,TSC22D1,MAOA,FHIT,LRRK1,RNF157,ZNF518B,SYK,CTNND2,CKAP4,ZNF629,MEF2C |
| 3.893e-03 | -5.55 | GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP | MSigDB lists | GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP | 192 | 31 | 17377 | 1707 |
FGFR4,DMXL2,GCA,GPM6A,UGT8,SH3BP2,MVK,PXN,PNP,PTPRU,NR4A1,GABRB2,EXOC6B,IL13RA1,KCND3,FRK,INPP1,STEAP1,SMPDL3B,DDIT4,ID3,PPM1E,INSIG1,BCHE,ATP7B,SERPINI1,GULP1,EPHB6,PLTP,MID1,PCSK6 |
| 3.893e-03 | -5.55 | human chr1p13.3 | chromosome location | human chr1p13.3 | 67 | 12 | 26185 | 1967 |
NBPF4,VAV3,GSTM2,CSF1,GSTM4,FAM102B,GSTM3,AMIGO1,GPSM2,KCNC4,NTNG1,CD53 |
| 3.895e-03 | -5.55 | neuron recognition | biological process | GO:0008038 | 34 | 9 | 17256 | 1658 |
EPHA3,CNTN4,ROBO2,CELSR3,NCAM2,AMIGO1,NRP1,FOXG1,SEMA3A |
| 3.895e-03 | -5.55 | negative regulation of response to drug | biological process | GO:2001024 | 34 | 9 | 17256 | 1658 |
GPR37,LRRK2,HGF,PDE8A,ABAT,RACK1,MET,PYCR1,SNCA |
| 3.895e-03 | -5.55 | cellular response to monoamine stimulus | biological process | GO:0071868 | 34 | 9 | 17256 | 1658 |
PRKN,ID1,ATF4,LRRK2,ADCY6,RYR2,PDE4D,ATP2B4,SNCA |
| 3.895e-03 | -5.55 | cellular response to catecholamine stimulus | biological process | GO:0071870 | 34 | 9 | 17256 | 1658 |
PRKN,ID1,ATF4,LRRK2,ADCY6,RYR2,PDE4D,ATP2B4,SNCA |
| 3.913e-03 | -5.54 | V$TITF1_Q3 | MSigDB lists | V$TITF1_Q3 | 224 | 35 | 17377 | 1707 |
KLF8,MXI1,DYRK3,ARHGEF11,GCAT,OTX1,SATB1,DACH2,NEO1,KCTD15,LHX6,CHRDL1,CNNM2,TSPAN13,PPP2R2B,ETV1,GPM6A,PXN,MSTN,JPH1,MGAT4B,PLS1,ZDHHC14,MAGI3,NSD1,NCAM2,GNAO1,PTK7,BMP1,HOXD13,PPARGC1A,MID1,SFN,CNTN1,MEF2C |
| 3.918e-03 | -5.54 | response to chemical | biological process | GO:0042221 | 4254 | 454 | 17256 | 1658 |
CGN,ACVR1,PDE1B,DNAJC3,LDLR,GATA3,NPM1,ENAH,CEBPA,STAT5B,CHAC1,PRKCA,RAC3,AARS,STK24,SKI,TYMP,FBXO32,TGFBR3,PMAIP1,SLC22A18,RAP2A,CHRDL1,GSTM3,TSHR,NKX2-1,GLDC,GDAP1,MEIS2,SMAD9,NR6A1,ACVR1C,DCC,LRRK2,BNIP3L,FEZ1,PRKAR2B,AGO4,ABCC2,FGF17,F12,ACVR2B,GNAI1,PYCR1,AHRR,SLC7A1,ENPP1,NCKAP1L,ATP7B,SEMA3C,MAPK13,NRP1,TPM1,UNC5B,MEF2C,EFNB2,LATS2,SCN5A,GNG12,INPPL1,ALOX5AP,GABRB2,CYP2J2,ITGA6,DHCR24,OPHN1,SLC36A4,TNFRSF10C,SLC1A3,ADSSL1,TNFRSF19,FOXG1,GAS1,RPL13A,CHN1,CNTN4,SLC7A11,FLRT3,MYC,SREBF1,GRIP1,NCAM1,STXBP1,AGL,GFRA1,CHRM3,HMGCR,EPB41L5,BDNF,PNP,SLC36A1,STAT4,MGST3,VLDLR,EFHC2,ARID5B,FASN,FHL2,CALCRL,RYR2,OR11H4,PLCB1,FAM162A,CPEB1,MMP15,SH3GL2,GSTO2,PMEPA1,PELI2,THBS4,MATN2,SQLE,SELENOM,HOXD13,TRPC3,SMYD3,AMPD1,EPHA3,PLA2G4A,PLXNA2,IL13RA1,MAPK4,CHUK,COLEC10,NRXN1,SLC19A2,ZFYVE9,TXNRD3,PLPP1,TLR3,ASNS,CHRNA5,KMO,DAB2IP,PDE4D,SERPINH1,SNX10,DOCK8,GAB2,FZD1,TRDMT1,MYLK3,COL6A2,GAPDH,PDK1,FZD4,PFKFB2,PREX1,ADCY1,SATB2,WNT11,ATF3,PRKCQ,ATOH1,FGFR1,ISG20,SNCA,IRS2,CXCL10,PEMT,WFS1,ASIC1,PAM,HPGD,TNFSF15,KLF5,GRB10,BMPR1A,ATG5,MAPK10,HOXB9,NR3C2,MID1,CGB2,PLSCR4,EDA2R,ROBO2,ESRP1,IPO5,KIF5C,GPR180,GAS6,P2RY1,EPHB1,NEDD4,NEO1,HMGCS1,BHLHA15,GHR,YBX3,MYO6,ERRFI1,GFI1,SMAD6,SPRY2,ZFP36L2,FES,VEGFC,PDLIM7,TRPM4,SLC40A1,VAV3,PXN,GSTM2,PTPN13,RAPGEF2,AK4,GAREM1,RACK1,GPLD1,CEBPB,GALNT3,ID3,TRIB3,OR2T33,TERT,GNAO1,XBP1,PCGF2,BMP4,CMPK2,TNFRSF17,CERS1,FOXA1,BTRC,LARP1,DDIT3,OCLN,ATP2B4,ATP1A3,ACSL1,FGF13,TRIM16,KIF5A,LILRB1,ASS1,ITPR2,ABAT,RBM11,F3,GSDME,CPNE2,PPM1E,ITGB3,TRPC1,PCOLCE2,TLR4,OR2W3,ETV1,IL1RAP,SLIT2,PDGFRB,PRKACB,LAMP3,CYP1B1,SLC3A2,SESN2,GCNT2,ATF4,ANK2,NFE2L1,YAP1,PLEKHA1,BATF,SESN1,GSN,KCNMB4,INSIG1,MAP2,GNB4,ERN1,TNFRSF1A,OXTR,TNFSF4,PPARGC1A,MAGI2,RRAGD,BCL11B,PRKAA2,RUNX2,LGALS3,FN1,HID1,ATP6V1E2,MLC1,PHGDH,DOK5,IL18R1,DDIT4,NUMBL,EEF2,SLC30A4,ZNF354A,IGF1R,SEMA4F,CA2,GATA2,BCHE,LRP6,INAVA,ADCY6,BNIP3,NCEH1,CEBPD,NOS3,PAK1,FGFR4,DPYSL5,HBG2,UNC5C,IL17RD,RHOQ,MSTN,GSTM4,HOMER2,EDEM3,EFNA3,SLITRK5,PDE8A,SDK1,HERPUD1,BAIAP2,MAPKAPK2,RIPOR2,HEYL,CSF1,SH3BP4,HK2,RAB31,PTPRN2,PLD1,SEMA3A,TESC,MME,CREB3L2,CXCR5,PRKN,SORBS1,ID1,CELSR3,IL15,RBFOX2,COL18A1,OR51B4,NTRK3,SLC7A2,CANX,DOCK2,SEMA6A,PPP1R9A,CYP26A1,RIDA,UNC13B,BCL6,ACVR2A,MET,HSPA2,SEMA6C,SNAI2,CTH,FER,TMEM67,EVL,UROS,PTPRU,NOP53,PTPN6,FGF12,ACO1,CHRNA6,VIM,GSTO1,RARRES2,CD40,SMAD3,MSC,NRG3,PTPRJ,TRIM34,PTK7,EIF4EBP1,GBP1,ITGA2,RGS10,MAOA,HGF,CYP2U1,LIFR,PSPH,HEY1,OR51B5,SLC6A9,IL32,BMPR2,REL,CMTM8,APBB1,LRP4,TNFSF13B,SELL,GABRG2,HBE1,BMP6,NKX6-1,FOXP2,RAB11FIP5,SCN1B,DSG2,PRKCD,STC2,GTF2F2,KCNMB3,TFAP2A,IPCEF1,KLF9,IQGAP3,PCK2,ESD,TNFRSF11A,SYK,FKBP14,ATP2B1,CES3,DUSP1,MSX1,KDM5B,HNF4G,NR4A1,ESRRG,NUGGC,LITAF,FERMT2,MARS,TLR6,ILDR2,LEPR,LRAT,MGMT,DKK1,EDA,FAT4,FBN1,ACER2,MAP2K6,CTSV,DLG2,PAX9,SLC1A5,TBC1D4,IL9R,KIF1B,PTGES,CACNA2D1,ABCG1 |
| 3.923e-03 | -5.54 | V$HP1SITEFACTOR_Q6 | MSigDB lists | V$HP1SITEFACTOR_Q6 | 216 | 34 | 17377 | 1707 |
TYRO3,LRFN5,ATP6V1E2,CADM2,TNKS1BP1,IKZF2,MECOM,PLS3,FOXP2,ZNF827,LHX6,CHRDL1,BCL6,PJA1,POU3F3,PRKACB,RIN2,GCNT2,RHOQ,TUBA1A,MSTN,ESRRG,VLDLR,PRICKLE1,CALCRL,MBNL2,BCL11A,ZIC1,ID3,MAP2K6,DLG2,DSEL,MAPK10,KIF1B |
| 3.932e-03 | -5.54 | positive regulation of protein kinase activity | biological process | GO:0045860 | 522 | 69 | 17256 | 1658 |
NEK10,ACSL1,AVPI1,FGF13,NTRK3,LCP2,SNX9,PIBF1,PPP1R9A,STK24,TLR3,ITGB3,DAB2IP,TLR4,PRKACB,PDGFRB,RASGRP1,FZD4,TGFA,LRRK2,ADCY1,WNT11,PRKAR2B,ACVR2B,CD40,FGFR1,SNCA,NRG3,GPRC5B,NCKAP1L,ERN1,MAP3K21,DUSP19,TNFSF15,HGF,DIRAS1,MAPK10,CACUL1,TENM1,TNIK,PAK5,FZD8,SLK,GAS6,PKN1,TPD52L1,GHR,PRKCD,ADCY6,INAVA,AFAP1L2,IQGAP3,TNFRSF11A,SPRY2,SYK,PAK1,RAPGEF2,VLDLR,STRADB,DUSP9,TLR6,DKK1,PTPRC,MAPKAPK2,CSF1,MAP2K6,BMP4,MAP3K20,ATP2B4 |
| 3.946e-03 | -5.53 | GO_REGULATION_OF_B_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_B_CELL_DIFFERENTIATION | 22 | 7 | 17377 | 1707 |
STAT5B,PRDM1,IKZF3,NCKAP1L,PTPN6,SYK,XBP1 |
| 3.946e-03 | -5.53 | WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_DN | MSigDB lists | WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_DN | 22 | 7 | 17377 | 1707 |
CALCRL,EBF1,ITGB7,GEM,PTPRCAP,SATB1,TSC22D1 |
| 3.946e-03 | -5.53 | GO_CEREBRAL_CORTEX_NEURON_DIFFERENTIATION | MSigDB lists | GO_CEREBRAL_CORTEX_NEURON_DIFFERENTIATION | 22 | 7 | 17377 | 1707 |
DLX2,EOMES,GDPD5,CHD5,RAC3,LHX6,NKX2-1 |
| 3.946e-03 | -5.53 | REACTOME_SIGNALING_BY_BMP | MSigDB lists | REACTOME_SIGNALING_BY_BMP | 22 | 7 | 17377 | 1707 |
ACVR2A,ACVR2B,BMPR1A,BMPR2,SMAD6,CHRDL1,SKI |
| 3.946e-03 | -5.53 | GO_GLUTATHIONE_DERIVATIVE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_GLUTATHIONE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 22 | 7 | 17377 | 1707 |
GSTM3,GSTO1,GSTM2,GSTO2,ESD,MGST3,GSTM4 |
| 3.946e-03 | -5.53 | NEWMAN_ERCC6_TARGETS_UP | MSigDB lists | NEWMAN_ERCC6_TARGETS_UP | 22 | 7 | 17377 | 1707 |
HERC5,SLC7A11,PMAIP1,STEAP1,KIAA1211,LITAF,PCSK5 |
| 3.946e-03 | -5.53 | GO_GLUTATHIONE_DERIVATIVE_METABOLIC_PROCESS | MSigDB lists | GO_GLUTATHIONE_DERIVATIVE_METABOLIC_PROCESS | 22 | 7 | 17377 | 1707 |
GSTM3,GSTO1,GSTM2,GSTO2,ESD,MGST3,GSTM4 |
| 3.955e-03 | -5.53 | GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS | 537 | 72 | 17377 | 1707 |
ACVR1,SORBS1,ACSL1,RBFOX2,ASS1,STAT5B,FBXO32,ASNS,TSHR,SLIT2,PRKACB,FZD1,FER,NR6A1,ADCY1,PRKAR2B,IRS2,ENPP1,EIF4EBP1,GNB4,ITGA2,GRB10,OXTR,TNFSF4,PPARGC1A,NR3C2,HEY1,MEF2C,PRKAA2,GNG12,LATS2,ROBO2,FN1,ATP6V1E2,NEDD4,NKX6-1,HMGCS1,CA2,IGF1R,GHR,PRKCD,SREBF1,GRIP1,ADCY6,SGK1,KLF9,ERRFI1,ATP2B1,DUSP1,PAK1,PXN,RHOQ,MSTN,HNF4G,NR4A1,ESRRG,VLDLR,FHL2,LEPR,BAIAP2,CPEB1,GPLD1,TRIB3,FBN1,PLOD2,PMEPA1,XBP1,RAB31,BMP4,TBC1D4,SMYD3,ATP1A3 |
| 3.977e-03 | -5.53 | large_intestine-colon-carcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma | 2677 | 300 | 17385 | 1698 |
FAM171B,MYCBP2,CGN,ADAL,LANCL3,LGR4,SIDT1,GRIK2,PRSS12,ATP8A1,CTBP2,KIAA1217,AARS,NCS1,PCDH7,TRPS1,TXNDC5,VWA5A,CPE,ERGIC1,DCDC1,SMAD9,DCC,LRRK2,DEPTOR,MSRB3,KCND3,ACVR2B,GPC6,GNAI1,ENPP6,RASGRF2,ALDOA,ADRB1,SEMA3C,INPP5F,SPOCK3,LZTS1,CARS,LRFN5,LATS2,CELSR1,PTPRD,TBC1D1,GABRB2,CYP2J2,ITGA6,TJP1,BTBD9,SLC1A3,APBA1,FOXG1,DYNC1I1,IL17D,SYCP2,NAV1,FRY,CNTN4,C1QL4,SRGAP1,TOX,ALPK1,ST8SIA1,FIGN,FAM155A,AGL,HMGCR,RAPGEF4,FASN,KIAA1324L,PLS1,SHISA2,DAGLA,TMCO3,PELI2,THBS4,LRRIQ3,DYNC2LI1,TRPC3,ST14,OTX1,CHUK,NRXN1,CCDC120,TMEM53,ZNF827,SPEG,EPB41L3,CNKSR3,DAB2IP,DNAH5,FZD1,COL6A2,B3GALT1,SOX21,SHANK2,PANK1,SATB2,WNT11,PRKCQ,ATP1B1,DSP,TBC1D16,GABARAPL1,IRS2,IKZF3,PRKCB,LAMB1,ZNF704,PLEKHG1,KLF5,PURG,FARP1,MXI1,WDR17,ANKRD13B,ROBO2,ATP9A,HERC5,PSD3,KCNC4,COL27A1,NEDD4,NEO1,HMGCS1,AFF2,GAS2L3,GHR,SMPDL3A,MED12L,TRPM4,PDLIM7,VAV3,ARAP2,ATP11A,GALNT3,NSD1,PLPPR2,MCC,SVIL,LARP1,EXPH5,SYT12,ACTL8,PTPN21,UGDH,LMCD1,ITPR2,HMCN1,F3,PLS3,ARHGEF10L,PPM1E,SIPA1L2,KCNN2,LRRC6,TMEM86A,ANKFN1,TMEM132E,TLN2,CYP1B1,PGBD5,TNK2,ATL1,MARK1,GCNT2,SLC3A2,SKAP2,SPOCD1,NFE2L1,ROR1,BATF,CRYBG3,KLF12,MAP2,TIGD4,OXTR,PCSK5,RRAGD,SV2B,ZNF395,RHOBTB1,CHCHD7,SEC24D,UBASH3B,RIMKLA,LAMC3,SETBP1,ZIC2,GALNT13,CD7,NUMBL,IGF1R,ABCA5,LRP6,ADCY6,LIMCH1,CAND2,PCDH10,MID2,MSTN,EDEM3,EFNA3,SDK1,BAIAP2,GLCE,GRIK4,KIAA0355,SLC2A6,HK2,RAI14,SH3BP4,PTPRN2,NXPH4,DISP2,MME,DMXL2,ZSWIM5,AKAP5,CELSR3,XYLT1,ARHGAP22,NTRK3,SEZ6L2,LPIN3,DENND3,PPP1R9A,DOCK2,FAM131B,COL22A1,UNC13B,PPFIBP1,LHX6,ACVR2A,MDH1B,MET,CLVS2,HSPA2,HRASLS,CTH,INTU,PHLDB2,FER,EVL,TMEM67,LRRC8B,TES,ACO1,RARRES2,ZNF569,BCL11A,WARS,RANBP2,NRG3,PTPRJ,GBP1,NECAB2,LPAR2,DYRK3,BMPR2,GRB14,ARHGEF11,CLGN,RUSC2,REL,LRP4,CLSTN2,PPP2R3A,PRKCD,KLF9,SH3PXD2B,ESD,SYK,DLGAP1,CARD6,MICAL2,LRRIQ1,NR4A1,FERMT2,MARS,AGAP2,TGDS,FNDC3A,LEPR,MAP1B,RERE,GPR37,ADAMTS17,SUGT1,FAT4,FBN1,UACA,KIAA0513,DLG2,PAX9,TBC1D4,MMP16,FILIP1,CACNA2D1,SLC16A10 |
| 3.980e-03 | -5.53 | nucleoside phosphate binding | molecular function | GO:1901265 | 2093 | 239 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,UGDH,TUBE1,ASS1,CTBP2,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,BAG3,RPS6KA2,KCNAB1,AKAP7,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,FAM114A2,ATP7B,ERN1,BDH2,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,CRYL1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,DHCR24,RIMKLA,RASL11B,GPSM2,PHGDH,ADSSL1,CHD5,GRPEL2,HSPA12B,ZBTB38,PRTFDC1,EEF2,IGF1R,ADCK1,ABCA5,APLF,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,NOS3,HMGCR,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,FASN,STRADB,OBSCN,CDC42BPA,LDHD,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SQLE,DHCR7,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,CHUK,MAPK4,NTRK3,GRK6,KIF21B,DDR1,DDX60L,TXNRD3,SPEG,ASNS,KMO,RPS6KL1,MYO3B,ACVR2A,MYH15,FHIT,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GAPDH,GARS,TUBA1A,PDK1,PFKFB2,MVD,CYB5R2,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,HPGD,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PARP9,PFKFB4,TRPM4,MICAL2,OPLAH,RAB3B,ALDH2,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,FMO4,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 |
| 3.983e-03 | -5.53 | kidney-Wilms_tumour | COSMIC cancer mutations | kidney-Wilms_tumour | 549 | 73 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,SP8,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,RASGRF2,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PKN1,EPHB1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,TMTC4,NUAK2,STRADB,OBSCN,CDC42BPA,LHPP,RERE,MAPKAPK2,TRIB3,FGR,PKN3,FAT1,AKT3,MAP2K6,NEK11 |
| 3.986e-03 | -5.52 | L-amino acid transport | biological process | GO:0015807 | 60 | 13 | 17256 | 1658 |
SLC7A1,SERINC5,SLC3A2,SLC6A9,SLC7A11,SLC36A1,SERINC2,SLC7A5,SLC36A4,SLC1A3,SLC7A2,SLC1A5,SLC43A1 |
| 3.989e-03 | -5.52 | chr13q22 | MSigDB lists | chr13q22 | 12 | 5 | 17377 | 1707 |
MYCBP2,ERCC5,NDFIP2,KLF12,SPRY2 |
| 3.989e-03 | -5.52 | GO_FOREBRAIN_NEURON_FATE_COMMITMENT | MSigDB lists | GO_FOREBRAIN_NEURON_FATE_COMMITMENT | 12 | 5 | 17377 | 1707 |
BCL11B,SATB2,DLX2,GATA2,NKX2-1 |
| 3.989e-03 | -5.52 | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP | MSigDB lists | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP | 12 | 5 | 17377 | 1707 |
TRIB3,CHAC1,SLC6A9,ISM1,ALDH1L2 |
| 3.989e-03 | -5.52 | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 12 | 5 | 17377 | 1707 |
CEBPB,ATF3,ATF4,DDIT3,XBP1 |
| 3.990e-03 | -5.52 | Prot-tyrosine_phosphatase-like | interpro domains | IPR029021 | 101 | 19 | 18492 | 1811 |
SSH3,DUSP8,PTPRU,PTPRD,PTPN6,PTPN13,PTPN21,DNAJC6,DUSP9,TNS1,PTPRC,PTPRJ,CDC14B,PALD1,DUSP19,PTPRS,PTPRN2,PTPRE,DUSP1 |
| 3.998e-03 | -5.52 | cytoplasmic side of plasma membrane | cellular component | GO:0009898 | 175 | 28 | 18223 | 1724 |
TNK2,FER,GNG12,FARP1,RASAL2,AKAP5,CYTH3,LITAF,FERMT2,RASA3,HIP1,CHUK,SNAP25,RGS7,FRK,SNX9,CACNB4,GNAI1,FGR,KCNAB1,GNAO1,DAB2IP,GEM,NPTXR,ERRFI1,SYK,FES,ATP2B1 |
| 4.002e-03 | -5.52 | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN | MSigDB lists | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN | 161 | 27 | 17377 | 1707 |
EML5,PDK1,CLYBL,PTPN6,ST6GAL1,RAPGEF4,SELL,CALCRL,TDRKH,SESN1,KBTBD11,SATB1,SLCO3A1,ADAMTS17,ID3,TGFBR3,RALGPS2,PMEPA1,MYC,RGS10,ATRNL1,RCN3,ST8SIA1,RRAS2,RNF122,AMPD1,NKX2-1 |
| 4.011e-03 | -5.52 | MULLIGHAN_MLL_SIGNATURE_2_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_DN | 265 | 40 | 17377 | 1707 |
NBL1,TRIM16,MCTP2,LAMC3,ASS1,NPM1,STAT5B,NEDD4,GALNT1,RPS6KA2,PMAIP1,MCF2L,CERS4,SCN2A,PTPRCAP,VGLL4,MAST4,B4GALT6,MN1,DBN1,VAV3,ARAP2,KDM5B,ABCC4,LRRC8B,STAT4,DEPTOR,PRKCQ,CCNG1,ATP1B1,SESN1,FGFR1,PYCR1,SLC7A1,RANBP2,CLMN,HPGD,EGFL7,HGF,STOM |
| 4.014e-03 | -5.52 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN | 138 | 24 | 17377 | 1707 |
PNP,RECK,COL4A5,ATF3,ATP11A,DDR1,SESN1,SLCO3A1,GAS1,RAB11FIP5,ID3,TCF7L1,ABLIM1,GSN,INSIG1,FBN1,SEMA3C,GRB10,SLC1A5,PLTP,SNX10,SMAD6,RBMS2,DUSP1 |
| 4.040e-03 | -5.51 | Hr1 | smart domains | SM00742 | 7 | 4 | 9493 | 1056 |
RHPN2,RTKN2,PKN1,PKN3 |
| 4.048e-03 | -5.51 | Serine biosynthesis | REACTOME pathways | R-HSA-977347 | 8 | 4 | 10287 | 971 |
SERINC5,PHGDH,PSPH,SERINC2 |
| 4.057e-03 | -5.51 | COL4A3BP (collagen type IV alpha 3 binding protein) | protein interactions | 10087 | 27 | 8 | 17029 | 1718 |
NAP1L5,CBS,RANBP2,MARK1,COL4A3,ENTPD7,ACTL8,PNMA2 |
| 4.061e-03 | -5.51 | mesoderm formation | biological process | GO:0001707 | 67 | 14 | 17256 | 1658 |
SMAD3,EPB41L5,ACVR1,EOMES,BMPR2,WLS,APELA,ITGB3,ITGA2,WNT11,BMPR1A,BMP4,SIX2,DKK1 |
| 4.062e-03 | -5.51 | V$CEBP_Q2_01 | MSigDB lists | V$CEBP_Q2_01 | 257 | 39 | 17377 | 1707 |
PLA2G4A,CGN,DYRK3,TNFSF13B,GABRR2,DOCK3,ABHD6,NEO1,PCDH7,EFEMP1,LHX6,STC2,BCL6,TSC22D1,PRKG1,SLC6A15,BEND4,EPHB6,PDE4D,FIGN,MED12L,NDUFA4L2,SLC40A1,BDNF,PPP1R3D,CRIM1,PLS1,PLCB1,CLN5,HOXA1,TCF7L1,ID3,KLF12,MAP2K6,KLF5,ZBTB20,TNFSF15,DLG2,SPRY4 |
| 4.071e-03 | -5.50 | cell-cell contact zone | cellular component | GO:0044291 | 68 | 14 | 18223 | 1724 |
PAK1,SCN5A,FGF13,SCN1B,TMEM65,ANK2,DSG2,PKP2,ATP1B1,SCN2A,DSP,CDH2,JAM3,GJC1 |
| 4.077e-03 | -5.50 | human chr5q35.2 | chromosome location | human chr5q35.2 | 43 | 9 | 26185 | 1967 |
FGFR4,SFXN1,GPRIN1,STC2,RNF44,TSPAN17,MIR1271,THOC3,BOD1 |
| 4.080e-03 | -5.50 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_UP | 169 | 28 | 17377 | 1707 |
ARHGAP26,PXN,CELSR1,SKAP2,BLVRB,NUAK2,LITAF,PREX1,PDE8A,ABHD4,SNX9,SMPDL3B,CXCL10,TIFA,FGR,ASNS,TRIM34,EOMES,PIK3AP1,RAB31,RALGAPA2,GEM,POU2F2,NRP1,RAPGEF5,NEB,SLC43A1,DENND5B |
| 4.080e-03 | -5.50 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_DN | 169 | 28 | 17377 | 1707 |
TRPM4,ARAP2,ARHGEF11,HERC5,SLC25A28,ATOH1,HERC6,PGAP1,COL27A1,GAS1,WARS,GALNT3,OTUD1,HPSE,PMAIP1,CNKSR3,ERN1,FAM107B,BBC3,TNFSF15,HS3ST3B1,SP140,CMPK2,SLFN5,SLC9B1,MLLT3,NOS3,LAMP3 |
| 4.080e-03 | -5.50 | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | 169 | 28 | 17377 | 1707 |
SLC3A2,GARS,SESN2,DYRK3,PNP,LRRC8B,UBASH3B,HECW2,FERMT2,P2RY1,CHAC1,CHSY1,FNDC3A,SNX9,ASPH,ZSCAN5A,F3,TBC1D2,CEBPB,BAG3,INSIG1,CSF1,CCNA1,SGK1,TNFSF15,GEM,DUSP1,RRAGD |
| 4.080e-03 | -5.50 | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_UP | MSigDB lists | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_UP | 169 | 28 | 17377 | 1707 |
IL17RD,GPM6A,DUSP8,GJB2,GRID1,GPR180,SNAP25,EPHB1,PALLD,NDFIP2,MKX,PLS3,GPR37,IRS2,ZNF711,PRTFDC1,IGF1R,LRRN1,TDO2,ZNF440,PLK2,RAP2A,EIF1,RAB27B,KLHL29,MAST4,DUSP1,LPP |
| 4.099e-03 | -5.50 | Rac guanyl-nucleotide exchange factor activity | molecular function | GO:0030676 | 17 | 6 | 17224 | 1680 |
VAV3,FARP1,DOCK2,EPS8,PREX1,SPATA13 |
| 4.109e-03 | -5.49 | V$AFP1_Q6 | MSigDB lists | V$AFP1_Q6 | 249 | 38 | 17377 | 1707 |
LRFN5,C1QTNF3,RBFOX2,MCTP2,CREB5,ATXN7L1,EFEMP1,ABLIM1,EPB41L3,KCTD15,SEC16B,BACE2,MYC,CHRDL1,NDUFB8,HS3ST5,MYO3B,AGL,C15orf41,BDNF,MEIS2,PRDM13,FGF12,PACSIN3,ATF3,SATB2,ZFPM2,STEAP1,HOXA1,SPATA7,ZIC1,TEX15,PELI2,HGF,SEMA3C,DLX2,SHOX2,FOXA1 |
| 4.119e-03 | -5.49 | GO_TRANSITION_METAL_ION_HOMEOSTASIS | MSigDB lists | GO_TRANSITION_METAL_ION_HOMEOSTASIS | 101 | 19 | 17377 | 1707 |
SLC40A1,SLC39A8,SFXN4,ATOX1,ACO1,SLC25A28,BTBD9,SFXN3,BMP6,STEAP1,NEO1,SLC39A14,SFXN1,SLC30A4,SLC22A17,ATP7B,MYC,BDH2,STEAP3 |
| 4.130e-03 | -5.49 | TYR_PHOSPHATASE_PTP | prosite domains | PS50055 | 37 | 10 | 12060 | 1278 |
PTPRC,PTPRJ,PTPRU,PTPRD,PTPN6,PTPN13,PTPN21,PTPRS,PTPRN2,PTPRE |
| 4.137e-03 | -5.49 | GO_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | MSigDB lists | GO_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | 59 | 13 | 17377 | 1707 |
INHBC,ACVR1,BMPR2,MSTN,PMEPA1,INHBE,BMP1,ACVR2A,BMP4,BMPR1A,SMAD6,BMP6,DKK1 |
| 4.137e-03 | -5.49 | GO_CHONDROCYTE_DIFFERENTIATION | MSigDB lists | GO_CHONDROCYTE_DIFFERENTIATION | 59 | 13 | 17377 | 1707 |
CREB3L2,RUNX2,BMPR2,BMP4,BMPR1A,CHSY1,SERPINH1,SHOX2,SIX2,FGFR1,COL27A1,GPLD1,MEF2C |
| 4.137e-03 | -5.49 | CUI_GLUCOSE_DEPRIVATION | MSigDB lists | CUI_GLUCOSE_DEPRIVATION | 59 | 13 | 17377 | 1707 |
PRAME,SLC3A2,ASNS,CLGN,DNAJC3,SGK3,KIF5C,PCK2,CANX,OCLN,DDIT4,PYCR1,TRPS1 |
| 4.137e-03 | -5.49 | BILBAN_B_CLL_LPL_UP | MSigDB lists | BILBAN_B_CLL_LPL_UP | 59 | 13 | 17377 | 1707 |
CREB3L2,CYP51A1,SLC39A14,BCL7A,SERINC5,BACH2,FRY,TBC1D1,ST6GAL1,ATOX1,BNIP3L,IGSF3,PNMA2 |
| 4.140e-03 | -5.49 | GSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_UP | MSigDB lists | GSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_UP | 177 | 29 | 17377 | 1707 |
SUSD3,MPZL3,RGS16,CD55,PNP,TES,HEBP1,LITAF,SPATA13,RASA3,ADAMTS6,COTL1,PGAP1,RPL13A,BAG3,NELL2,RPL12,GYPC,EEF2,MGAT1,MPP7,GPR155,INPP4B,KIAA0513,P4HA1,SEMA3A,MLLT3,LAMP3,DOCK9 |
| 4.140e-03 | -5.49 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_DN | 177 | 29 | 17377 | 1707 |
CARS,PPP4R4,RNF145,RNF144A,SLC27A2,PTPN13,DNAJC6,AK4,IL13RA1,PRDM1,BATF,SATB1,BATF3,HEG1,EBF1,SLC7A1,TIFA,GATA2,SLC7A5,BCL6,SGK1,TMOD2,MDH1B,TNFSF4,PTPRCAP,TANC2,LRP12,SLC16A10,DUSP1 |
| 4.142e-03 | -5.49 | Dopamine Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-212676 | 23 | 7 | 10287 | 971 |
PPFIA4,LIN7A,SNAP25,UNC13B,APBA1,STXBP1,PPFIA2 |
| 4.143e-03 | -5.49 | negative regulation of cell death | biological process | GO:0060548 | 1008 | 122 | 17256 | 1658 |
EPHA3,PRKN,BTC,ID1,ACVR1,GRIK2,DNAJC3,LILRB1,GATA3,NPM1,STAT5B,NTRK3,PRKCA,DDR1,AARS,EYA4,TXNDC5,BAG3,ASNS,MAGEA3,BCL6,CTTN,EPHB6,MET,FANK1,ENO1,POU3F3,DOCK8,SNAI2,PDGFRB,LAMP3,FZD1,CTH,PRAME,ATF4,WISP3,NKX3-2,LRRK2,BNIP3L,YAP1,AGO4,WNT11,PRKCQ,ROR1,ATOH1,FGFR1,SNCA,PYCR1,IRS2,SMAD3,BEX3,SH3RF1,NCKAP1L,PLK2,WFS1,MAP3K21,NCOA7,HGF,ERCC5,ATG5,NRP1,PPARGC1A,UNC5B,RETREG1,MEF2C,BCL11B,PRKAA2,TYRO3,DYRK3,LGALS3,PAK5,GABRB2,ITGA6,REL,DHCR24,SLC25A27,GAS6,TNFRSF10C,EPHB1,MECOM,SYCP2,BNIP1,IGF1R,GATA2,MYC,PRKCD,PRELID1,SGK3,TFAP2A,LRP6,BNIP3,YBX3,SMAD6,STXBP1,SPRY2,ZNF385A,NOS3,HMGCR,DUSP1,FGFR4,SLC40A1,BDNF,MSX1,NUGGC,FHL2,NUAK2,STRADB,PDE8A,AGAP2,RACK1,ZFPM2,MGMT,HERPUD1,DKK1,CEBPB,GPR37,TERT,XBP1,PCGF2,BMP4,SFN,TPT1 |
| 4.146e-03 | -5.49 | negative regulation of intracellular signal transduction | biological process | GO:1902532 | 541 | 71 | 17256 | 1658 |
PRKN,DUSP8,RASAL2,NDRG2,PIBF1,DACT1,CNKSR3,MAGEA3,BCL6,DAB2IP,WWC2,MET,TLR4,ENO1,SLIT2,SNAI2,SESN2,NOP53,PTPN6,LRRK2,DEPTOR,PREX1,RNF125,ATF3,GSTO1,PLEKHA1,SYNJ2BP,SESN1,CAMK2N1,PTPRJ,GBP1,WFS1,DUSP19,INPP5F,SPRY4,MAGI2,PRKAA2,DYRK3,C1QTNF3,ARHGAP44,DDIT4,MECOM,IGF1R,FLRT3,MYC,PRKCD,C1QL4,ERRFI1,YBX3,SPRY2,ZNF385A,DUSP1,HMGCR,RNF152,GSTM2,MSTN,LITAF,WWC1,DUSP9,RASA3,RACK1,HERPUD1,TRIB3,MYADM,RIPOR2,XBP1,SH3BP4,BMP4,ATP2B4,DDIT3,TPT1 |
| 4.149e-03 | -5.48 | V$TEF_Q6 | MSigDB lists | V$TEF_Q6 | 241 | 37 | 17377 | 1707 |
OTX1,CADM2,ZIC2,CREB5,IKZF2,SLCO3A1,HPCAL4,HMCN1,NEDD4,NEO1,IGF1R,RALGPS2,FRY,GRHL1,KCNS3,PRICKLE2,PPP2R2B,ST8SIA1,SCN2A,SPRY2,PRKACB,NKX2-1,DPP10,RHOQ,CRIM1,FGF12,DHX32,PDLIM3,KLF12,GPRC5B,MAP2,KIAA0355,ITGBL1,PELI2,DLG2,NRP1,HEY1 |
| 4.151e-03 | -5.48 | phosphatidylinositol phosphate binding | molecular function | GO:1901981 | 147 | 25 | 17224 | 1680 |
ARAP2,MARK1,MYO10,PLEKHA8,STXBP6,PLEKHA5,CYTH3,MYO1B,FERMT2,HIP1,PLEKHA1,PLCB1,PFN2,GSDME,SCIN,TECPR1,FCHO2,ZFYVE28,OSBPL5,LAPTM4B,DAB2IP,SH3PXD2B,DENND1C,CLVS2,GAB2 |
| 4.154e-03 | -5.48 | V$OCT1_07 | MSigDB lists | V$OCT1_07 | 146 | 25 | 17377 | 1707 |
BCL11B,BDNF,LRFN5,NEK10,FZD4,ESRRG,NFIA,WNT11,ATOH1,PLCB1,NEDD4,ZIC1,NEO1,MTUS1,FOXP2,TUBB4A,RALGPS2,BACE2,RAB26,SCRN1,PRICKLE2,TMOD2,ETV1,MYT1,MID1 |
| 4.166e-03 | -5.48 | Wilms_tumour | COSMIC cancer mutations | Wilms_tumour | 550 | 73 | 17385 | 1698 |
EPHA3,NEK10,ACVR1,CHUK,NTRK3,GRK6,PRKCA,DDR1,SP8,STK24,SPEG,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,FRK,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,RASGRF2,ERN1,MAPK13,BMPR1A,MAST1,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PKN1,EPHB1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,ALPK1,SYK,FES,FGFR4,PAK1,TMTC4,NUAK2,STRADB,OBSCN,CDC42BPA,LHPP,RERE,MAPKAPK2,TRIB3,FGR,PKN3,FAT1,AKT3,MAP2K6,NEK11 |
| 4.176e-03 | -5.48 | GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | MSigDB lists | GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 46 | 11 | 17377 | 1707 |
SMAD3,PAK1,PPM1E,EVL,ID1,GPR65,WNT11,PRKCQ,SORBS3,TPM1,PFN2 |
| 4.182e-03 | -5.48 | Ras guanyl-nucleotide exchange factor activity | molecular function | GO:0005088 | 251 | 38 | 17224 | 1680 |
BTC,FARP1,ARHGEF11,DOCK1,EPS8,DENND3,DOCK2,TIAM2,ARHGEF10L,MCF2L,DENND1C,MET,NCAM1,GFRA1,RAPGEF5,RASGRP1,PDGFRB,FGFR4,VAV3,RIN2,ARHGEF28,RAPGEF2,MCF2L2,RAPGEF4,SPATA13,PREX1,OBSCN,FGF17,SERGEF,FGFR1,ARHGEF26,IRS2,RASGRF2,PLEKHG1,ADRB1,GRIN2D,HGF,DENND5B |
| 4.184e-03 | -5.48 | GSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN | MSigDB lists | GSE22589_HEALTHY_VS_HIV_INFECTED_DC_DN | 185 | 30 | 17377 | 1707 |
CARD6,ST14,LRRK2,SLC7A2,NPC2,GPSM2,HERC6,LCP2,TTLL7,BAIAP2,DCBLD2,HTR7,MAPKAPK2,TMCO3,TLR3,SETDB2,GYPC,PLOD2,AKT3,PLK2,MATN2,ALDH1L1,CCDC122,ST8SIA1,GEM,FAR2,STXBP1,SLFN5,RBMS2,DIRC2 |
| 4.191e-03 | -5.47 | GO_ENDOCYTOSIS | MSigDB lists | GO_ENDOCYTOSIS | 460 | 63 | 17377 | 1707 |
TYRO3,INPPL1,DNM3,MRC2,PRSS12,DOCK1,ATP9A,SYT12,LRP4,LDLR,OPHN1,MSR1,LILRB1,GAS6,CANX,DNER,MLC1,SNX9,DOCK2,NEDD4,ZFYVE9,TXNDC5,GATA2,PRKCD,GHR,MARCH3,LRP6,GULP1,LOXL4,CTTN,PACSIN1,MYO6,SNX10,LRP3,SYK,LRP12,SNX7,PAK1,PDLIM7,RIN2,VAV3,TNK2,MYO10,LRRK2,VLDLR,PACSIN3,CALCRL,HIP1,BAIAP2,SNCA,MAPKAPK2,ENPP1,GSN,FGR,SH3GL2,FCHO2,NCKAP1L,WIPF3,RAB31,SH3BP4,INPP5F,FNBP1L,STON2 |
| 4.199e-03 | -5.47 | gland development | biological process | GO:0048732 | 400 | 55 | 17256 | 1658 |
BCL11B,TFCP2L1,PLAG1,GATA3,ASS1,CEBPA,STAT5B,DDR1,HMGCS1,ASNS,TGFBR3,GATA2,LRP6,PCK2,MET,TNFRSF11A,IGSF3,GLI1,NKX2-1,MSX1,CSN2,KDM5B,WLS,ARID5B,FASN,MAFB,AK4,WNT11,FGFR1,MGMT,CEBPB,SMAD3,IRS2,NRG3,EDA,CSF1,ATP7B,XBP1,ITGA2,PAM,HK2,SEMA3C,HGF,HOXD13,DBP,OXTR,BMPR1A,BMP4,NRP1,HOXB9,NKX2-8,SEMA3A,COBL,FOXA1,BTRC |
| 4.204e-03 | -5.47 | regulation of synaptic vesicle cycle | biological process | GO:0098693 | 47 | 11 | 17256 | 1658 |
DNM3,UNC13B,LRRK2,BTBD9,SEPT5,CDH2,STXBP1,MAGI2,PFN2,RIMS2,SNCA |
| 4.211e-03 | -5.47 | ITSN1 (intersectin 1) | protein interactions | 6453 | 113 | 21 | 17029 | 1718 |
DLGAP1,DISC1,SCAMP1,DSTN,KIF5A,PREX1,PACSIN3,HIP1,SNAP25,ZFPM2,PHGDH,CEP85L,SH3GL2,PIK3AP1,PPFIA2,RAI14,PIK3C2B,PDE4D,MAP3K20,STON2,SPRY2 |
| 4.211e-03 | -5.47 | LGALS8 (galectin 8) | protein interactions | 3964 | 113 | 21 | 17029 | 1718 |
TRPM4,MID2,MRC2,ABCC4,FN1,SLC36A1,C4A,CD276,ITGA6,SDK1,SLC12A6,SEZ6L2,FGFR1,HEG1,PTPRJ,TMEM237,NCR3LG1,ITGA2,ADCY6,KIAA1549,ATP2B4 |
| 4.213e-03 | -5.47 | GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 193 | 31 | 17377 | 1707 |
MARK1,SCAMP1,MYO10,UGDH,FERMT2,CR2,PRDM1,TGDS,IKZF2,FGFR1,NEDD4,PLS3,ISG20,GPR37,NAV1,KLF12,SLC30A4,FBN1,CSF1,WWTR1,OSBPL5,HK2,PAM,SEMA3C,NRP1,MET,HOXB9,DDIT3,CACNA2D1,SNAI2,B4GALT6 |
| 4.213e-03 | -5.47 | V$CEBP_C | MSigDB lists | V$CEBP_C | 193 | 31 | 17377 | 1707 |
BCL11B,PLA2G4A,BDNF,ACVR1,USP2,RHOQ,TUBA1A,CRIM1,PTPRU,PLAG1,FGF12,ROR1,P2RY1,CREB5,SAV1,MBNL2,RERE,GPLD1,ZIC1,CEBPB,SLC39A14,MAP2K6,STC2,ALDOA,TSC22D1,KLF5,DLG2,JAKMIP2,PDE4D,ETV1,OSBPL6 |
| 4.213e-03 | -5.47 | GSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_UP | MSigDB lists | GSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_UP | 193 | 31 | 17377 | 1707 |
PDLIM7,MYO1D,GSTM2,COL6A2,PPP4R4,TTC39B,ITPRIP,DOCK1,GALNT6,ESRRG,ITGA6,JPH1,SORBS3,CTBP2,TNS1,GSTO1,PKN1,HSPA12B,ADPRHL1,CA2,RNF217,PELI2,CLDN12,GSTM3,KLF9,RNF130,DENND1C,DOCK6,FRMD5,PDGFRB,DUSP1 |
| 4.213e-03 | -5.47 | GSE24142_DN2_VS_DN3_THYMOCYTE_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_UP | 193 | 31 | 17377 | 1707 |
PAK1,PDLIM7,VAV3,MRC2,DYRK3,SKAP2,ALOX5AP,DEPTOR,LITAF,VIM,NEDD4,CA13,BCL11A,SCIN,CEBPB,DOCK7,MYADM,RAB31,RAI14,GSTM3,STEAP3,EGFL7,CAB39L,LRRK1,MED7,CMPK2,PTPRE,CKAP4,FES,CSRP2,B4GALT6 |
| 4.213e-03 | -5.47 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP | 193 | 31 | 17377 | 1707 |
GPT2,SLC6A9,RUNX2,NR4A1,IPO5,LRMP,CRIP2,FHL2,RASL11B,TNS1,STAT5B,WNT11,AARS,CRYBG3,PRRG4,NCS1,PPP2R3A,PYCR1,MCOLN2,RND2,ATXN7L1,KIAA1958,ASNS,MSMO1,SCN1B,WFS1,FAM107B,KIAA0513,CKAP4,CTH,RRAGD |
| 4.221e-03 | -5.47 | cellular response to lipid | biological process | GO:0071396 | 488 | 65 | 17256 | 1658 |
EPHA3,IL15,RBFOX2,LDLR,LILRB1,ASS1,NTRK3,PLPP1,FBXO32,DAB2IP,PDE4D,TLR4,GDAP1,NR6A1,FZD4,ADCY1,YAP1,ABCC2,WNT11,CD40,GNAI1,CXCL10,INSIG1,PTK7,EIF4EBP1,ITGA2,TNFSF4,PPARGC1A,NR3C2,HEY1,MEF2C,PRKAA2,PLSCR4,MLC1,NEDD4,DDIT4,HMGCS1,SREBF1,ADCY6,GRIP1,LRP6,KLF9,ERRFI1,PCK2,GFI1,ZFP36L2,ATP2B1,NOS3,HNF4G,MSTN,ESRRG,NUGGC,NR4A1,FHL2,LITAF,GPLD1,CEBPB,ID3,PMEPA1,XBP1,BMP4,CMPK2,SMYD3,TESC,ATP1A3 |
| 4.228e-03 | -5.47 | V$OCT1_02 | MSigDB lists | V$OCT1_02 | 201 | 32 | 17377 | 1707 |
DOC2A,TYRO3,FGF13,CHCHD7,PLAG1,FZD8,GABRG2,PRDM8,ZIC2,TRPS1,FOXP2,PPFIA2,CHRDL1,ZNF521,PDE4D,TSPAN9,FES,DZANK1,ACVR1C,ESRRG,NPM3,NFIA,JAM3,FGFR1,ZIC1,ENTPD1,PTPRJ,MAP2,DLG2,ZBTB20,PPARGC1A,SEMA3A |
| 4.232e-03 | -5.47 | Morphine addiction | KEGG pathways | hsa05032 | 91 | 18 | 7161 | 730 |
GNG12,PDE1B,GABRB2,ADCY1,GABRG2,PDE8A,GABRR2,GRK6,PRKCA,GRK3,GNAI1,PRKCB,GNAO1,GNB4,PDE10A,ADCY6,PDE4D,PRKACB |
| 4.232e-03 | -5.47 | Morphine addiction | KEGG pathways | ko05032 | 91 | 18 | 7161 | 730 |
GNG12,PDE1B,GABRB2,ADCY1,GABRG2,PDE8A,GABRR2,GRK6,PRKCA,GRK3,GNAI1,PRKCB,GNAO1,GNB4,PDE10A,ADCY6,PDE4D,PRKACB |
| 4.244e-03 | -5.46 | GO_CELLULAR_RESPONSE_TO_LIPID | MSigDB lists | GO_CELLULAR_RESPONSE_TO_LIPID | 443 | 61 | 17377 | 1707 |
EPHA3,PRKAA2,PLSCR4,ACVR1,FN1,IL15,RBFOX2,LILRB1,ASS1,NTRK3,MLC1,NEDD4,FBXO32,HMGCS1,SREBF1,SGK1,LRP6,ADCY6,GRIP1,DAB2IP,KLF9,PDE4D,ERRFI1,GFI1,TLR4,ATP2B1,NOS3,FZD1,MSTN,HNF4G,FZD4,NR6A1,NR4A1,ESRRG,VLDLR,FHL2,LITAF,ADCY1,YAP1,WNT11,CD40,CPEB1,GPLD1,GNAI1,CEBPB,ID3,CXCL10,PMEPA1,PTK7,XBP1,ITGA2,BMP4,PPARGC1A,TNFSF4,CMPK2,NR3C2,TESC,SMYD3,ATP1A3,MEF2C,HEY1 |
| 4.245e-03 | -5.46 | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | MSigDB lists | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | 116 | 21 | 17377 | 1707 |
PRKAA2,GNG12,AKAP5,RAPGEF4,ADCY1,FASN,PRKAR2B,SNAP25,ITPR2,PRKCA,PLCB1,GNAI1,CACNB2,GNAO1,GNB4,KCNS3,ADCY6,MARCKS,STXBP1,PRKACB,CHRM3 |
| 4.245e-03 | -5.46 | GO_NEURON_SPINE | MSigDB lists | GO_NEURON_SPINE | 116 | 21 | 17377 | 1707 |
GPM6A,FARP1,DNM3,AKAP5,SHANK2,APBB1,OPHN1,PRKAR2B,ARHGAP32,SLC1A3,CANX,PPP1R9A,BAIAP2,ARHGAP44,MAP1B,KCNN2,MARCKS,CTTN,CTTNBP2,LZTS1,ATP1A3 |
| 4.248e-03 | -5.46 | LEI_HOXC8_TARGETS_DN | MSigDB lists | LEI_HOXC8_TARGETS_DN | 17 | 6 | 17377 | 1707 |
ASS1,ACTA2,CXCL10,NCAM1,PLAGL1,GAS1 |
| 4.248e-03 | -5.46 | INGA_TP53_TARGETS | MSigDB lists | INGA_TP53_TARGETS | 17 | 6 | 17377 | 1707 |
BBC3,CCNG1,PMAIP1,SESN1,SFN,IGFBP3 |
| 4.248e-03 | -5.46 | ONDER_CDH1_TARGETS_3_UP | MSigDB lists | ONDER_CDH1_TARGETS_3_UP | 17 | 6 | 17377 | 1707 |
KLF9,PRKCA,LEPR,CRIP2,STC2,CYP1B1 |
| 4.248e-03 | -5.46 | GENTILE_UV_RESPONSE_CLUSTER_D1 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D1 | 17 | 6 | 17377 | 1707 |
GEM,RND3,ASPH,ITGA6,DDIT4,DUSP1 |
| 4.248e-03 | -5.46 | JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN | MSigDB lists | JI_CARCINOGENESIS_BY_KRAS_AND_STK11_DN | 17 | 6 | 17377 | 1707 |
VEGFC,NCAM1,FN1,ITGBL1,FGFR1,PDGFRB |
| 4.248e-03 | -5.46 | TRAYNOR_RETT_SYNDROM_DN | MSigDB lists | TRAYNOR_RETT_SYNDROM_DN | 17 | 6 | 17377 | 1707 |
BEX4,KLF5,ENPP1,SEL1L3,P4HA2,ITGA6 |
| 4.249e-03 | -5.46 | regulation of ERK1 and ERK2 cascade | biological process | GO:0070372 | 314 | 45 | 17256 | 1658 |
EPHA3,TYRO3,NEK10,NECAB2,FN1,NDRG2,NTRK3,GAS6,P2RY1,EPHB1,PRKCA,DDR1,TGFBR3,IGF1R,CNKSR3,C1QL4,DAB2IP,EPHB6,MET,ERRFI1,TLR4,TNFRSF11A,SYK,SPRY2,PDGFRB,RASGRP1,HMGCR,DUSP1,FGFR4,GCNT2,RAPGEF2,PTPN6,PDE8A,ATF3,GAREM1,SYNJ2BP,ROR1,FGFR1,CAMK2N1,GBP1,APELA,MAP3K21,BMP4,SPRY4,NRP1 |
| 4.252e-03 | -5.46 | Tyr_kinase_cat_dom | interpro domains | IPR020635 | 80 | 16 | 18492 | 1811 |
EPHA3,FGFR4,TYRO3,FER,TNK2,NTRK3,EPHB1,DDR1,FRK,FGFR1,FGR,IGF1R,MET,SYK,FES,PDGFRB |
| 4.274e-03 | -5.46 | TF (transferrin) | protein interactions | 7018 | 45 | 11 | 17029 | 1718 |
SMAD3,SH3BP2,ALDH2,FN1,IGFBP6,MYC,GDPD1,LAMC3,CANX,CA8,IGFBP3 |
| 4.280e-03 | -5.45 | O-glycan biosynthesis, mucin type core | KEGG pathways | hsa_M00056 | 27 | 8 | 7161 | 730 |
GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT14,GALNT18 |
| 4.280e-03 | -5.45 | O-glycan biosynthesis, mucin type core | KEGG pathways | M00056 | 27 | 8 | 7161 | 730 |
GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT14,GALNT18 |
| 4.291e-03 | -5.45 | SH2 | interpro domains | IPR000980 | 109 | 20 | 18492 | 1811 |
RIN2,FER,VAV3,SH3BP2,INPPL1,SH2D2A,GRB14,PTPN6,STAT4,TNS1,STAT5B,LCP2,FRK,CHN1,CHN2,FGR,SHF,GRB10,SYK,FES |
| 4.296e-03 | -5.45 | GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_B_CELL_ACTIVATION | 66 | 14 | 17377 | 1707 |
PTPRC,IRS2,VAV3,NCKAP1L,XBP1,TNFSF13B,BCL6,STAT5B,PRDM1,TNFSF4,CD40,TLR4,SYK,MEF2C |
| 4.310e-03 | -5.45 | scaffold protein binding | molecular function | GO:0097110 | 53 | 12 | 17224 | 1680 |
SCN5A,AKAP5,LRP4,NLGN4X,VIM,CHUK,ITPR2,PDE4D,P2RY1,DSP,ATP2B4,NOS3 |
| 4.310e-03 | -5.45 | hydro-lyase activity | molecular function | GO:0016836 | 53 | 12 | 17224 | 1680 |
CA2,EHHADH,ENO2,UROS,HACD1,ACO1,FASN,CBS,TGDS,CA8,ENO1,CA13 |
| 4.315e-03 | -5.45 | regulation of Rho protein signal transduction | biological process | GO:0035023 | 134 | 23 | 17256 | 1658 |
VAV3,ARAP2,FARP1,ARHGEF28,ARHGEF11,GPR65,MCF2L2,EPS8,OPHN1,PREX1,SPATA13,OBSCN,TIAM2,ARHGEF26,ARHGEF10L,RIPOR2,RASGRF2,MCF2L,PLEKHG1,BCL6,NRP1,MET,PDGFRB |
| 4.321e-03 | -5.44 | G alpha (z) signalling events | REACTOME pathways | R-HSA-418597 | 48 | 11 | 10287 | 971 |
RGS17,GNG12,PRKCB,GNB4,PRKCD,ADCY1,RGS20,ADCY6,PRKCQ,PRKCA,GNAI1 |
| 4.327e-03 | -5.44 | MODULE_426 | MSigDB lists | MODULE_426 | 87 | 17 | 17377 | 1707 |
ARAP2,SYBU,KIF5C,MAPK4,GAS6,BCAN,MLC1,DYNC1I1,ISG20,SPNS1,CHN2,BCHE,RPS6KL1,TFAP2A,MAP7,CEBPD,IGSF3 |
| 4.327e-03 | -5.44 | ZHU_CMV_24_HR_DN | MSigDB lists | ZHU_CMV_24_HR_DN | 87 | 17 | 17377 | 1707 |
MN1,COL6A2,PTPN13,LDLR,ACO1,C1R,GAS1,PYCR1,CHN1,EFEMP1,TGFBR3,IGF1R,TNFRSF1A,ACTA2,TPM1,IGFBP3,CYP1B1 |
| 4.329e-03 | -5.44 | netrin-activated signaling pathway | biological process | GO:0038007 | 8 | 4 | 17256 | 1658 |
UNC5C,UNC5B,DCC,SHTN1 |
| 4.329e-03 | -5.44 | cerebral cortex tangential migration | biological process | GO:0021800 | 8 | 4 | 17256 | 1658 |
NRP1,SEMA3A,SLIT2,LHX6 |
| 4.329e-03 | -5.44 | regulation of heart rate by chemical signal | biological process | GO:0003062 | 8 | 4 | 17256 | 1658 |
PDE4D,TPM1,NOS1AP,SREBF1 |
| 4.349e-03 | -5.44 | GO_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 583 | 77 | 17377 | 1707 |
CACNG3,ATP8A1,MCOLN3,SLC7A2,ITPR2,SLC2A13,CACNB4,NCS1,SLC9A7,KCNN2,KCNAB1,CHRNA5,SLC22A18,KCNS3,SERINC2,TRPC1,SLC2A12,TMEM37,SCN2A,ATP6AP1L,SCN3A,KCNB2,GPM6A,SLC3A2,KCNIP3,KCNH5,SLC39A8,ATOX1,CHRNA6,KCND3,ATP1B1,SLC39A14,SLC7A1,KCNMB4,ATP7B,KCNG1,SLC9B1,DENND5B,KCNV1,ANO10,SCN5A,TMEM63C,SERINC5,SLC6A9,SCN8A,ATP6V1E2,SLC36A4,SLC12A6,SLC1A3,GAS6,KCNC4,MCU,MCOLN2,KCNJ4,SLC30A4,SCN1B,CACNB2,KCNMB3,SLC6A15,NIPAL2,SLC45A3,ATP2B1,TRPM4,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RASA3,RYR2,KCNK15,TMCO3,SLC2A6,SLC1A5,TRPC3,CACNA2D1,ATP2B4,ATP1A3 |
| 4.352e-03 | -5.44 | Laminin_G_2 | pfam domains | PF02210 | 34 | 9 | 17054 | 1666 |
NELL2,FAT4,CELSR1,CNTNAP3,CELSR3,FAT1,PROS1,GAS6,NRXN1 |
| 4.370e-03 | -5.43 | KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | MSigDB lists | KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC | 73 | 15 | 17377 | 1707 |
ITGB7,TCF7L1,CACNG3,CACNB2,ITGA6,DSG2,ITGB3,ITGA2,PKP2,RYR2,DSP,CACNB4,CDH2,CTNNA2,CACNA2D1 |
| 4.370e-03 | -5.43 | GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 73 | 15 | 17377 | 1707 |
SMAD3,PAK1,PPM1E,PHLDB2,EVL,ID1,GPR65,ASAP3,SORBS3,WNT11,PRKCQ,TMEFF2,TPM1,PFN2,PPP1R9A |
| 4.374e-03 | -5.43 | RTKN (rhotekin) | protein interactions | 6242 | 78 | 16 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,TANC2,KIF1B,OSBPL6,LARP1,GAB2 |
| 4.383e-03 | -5.43 | GNAI3 (G protein subunit alpha i3) | protein interactions | 2773 | 99 | 19 | 17029 | 1718 |
RGS16,CD55,ANKRD13B,FN1,PTPRU,GPSM1,RGS20,RASA3,PRKAR2B,GPSM2,RGS7,GNAI1,TXNDC5,RGS17,BAG3,GNAO1,GNB4,RGS10,TSHR |
| 4.384e-03 | -5.43 | WH1 | smart domains | SM00461 | 11 | 5 | 9493 | 1056 |
ENAH,EVL,SPRED3,HOMER2,HOMER3 |
| 4.389e-03 | -5.43 | GUANYLATE_KINASE_1 | prosite domains | PS00856 | 16 | 6 | 12060 | 1278 |
DLG2,MPP7,MAGI2,MPP1,MAGI3,MPP2 |
| 4.392e-03 | -5.43 | Fluid shear stress and atherosclerosis | KEGG pathways | hsa05418 | 142 | 25 | 7161 | 730 |
PRKAA2,ACVR1,GSTM2,BMPR2,MGST3,GSTM4,ASS1,CHUK,GSTO1,ACVR2B,RAC3,GSTO2,MAP2K6,AKT3,ITGB3,TNFRSF1A,GSTM3,ACVR2A,MAPK13,BMPR1A,BMP4,MAPK10,NOS3,DUSP1,MEF2C |
| 4.392e-03 | -5.43 | Fluid shear stress and atherosclerosis | KEGG pathways | ko05418 | 142 | 25 | 7161 | 730 |
PRKAA2,ACVR1,GSTM2,BMPR2,MGST3,GSTM4,ASS1,CHUK,GSTO1,ACVR2B,RAC3,GSTO2,MAP2K6,AKT3,ITGB3,TNFRSF1A,GSTM3,ACVR2A,MAPK13,BMPR1A,BMP4,MAPK10,NOS3,DUSP1,MEF2C |
| 4.404e-03 | -5.43 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | MSigDB lists | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | 28 | 8 | 17377 | 1707 |
PAK1,EVL,ROBO2,CAP2,SRGAP1,ENAH,PFN2,SLIT2 |
| 4.404e-03 | -5.43 | GO_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | MSigDB lists | GO_REGULATION_OF_HEART_RATE_BY_CARDIAC_CONDUCTION | 28 | 8 | 17377 | 1707 |
SCN5A,SCN1B,CACNB2,ANK2,DSG2,PKP2,DSP,CACNA2D1 |
| 4.404e-03 | -5.43 | LOPES_METHYLATED_IN_COLON_CANCER_DN | MSigDB lists | LOPES_METHYLATED_IN_COLON_CANCER_DN | 28 | 8 | 17377 | 1707 |
GATA3,BDNF,SORBS3,FHIT,SMAD9,TSHR,TERT,TFAP2A |
| 4.404e-03 | -5.43 | REACTOME_CA_DEPENDENT_EVENTS | MSigDB lists | REACTOME_CA_DEPENDENT_EVENTS | 28 | 8 | 17377 | 1707 |
PLA2G4A,PDE1B,PRKCD,ADCY1,ADCY6,PRKAR2B,PRKCA,PRKACB |
| 4.404e-03 | -5.43 | GO_SH2_DOMAIN_BINDING | MSigDB lists | GO_SH2_DOMAIN_BINDING | 28 | 8 | 17377 | 1707 |
INPPL1,PTPN6,LILRB1,AFAP1L2,SH3PXD2B,SYNGR3,KHDRBS2,SKAP1 |
| 4.404e-03 | -5.43 | MODULE_202 | MSigDB lists | MODULE_202 | 28 | 8 | 17377 | 1707 |
GSN,ABLIM1,DSTN,SVIL,ACTA2,MYOM2,PFN2,NEB |
| 4.411e-03 | -5.42 | TRAYNOR_RETT_SYNDROM_UP | MSigDB lists | TRAYNOR_RETT_SYNDROM_UP | 40 | 10 | 17377 | 1707 |
PLA2G4A,GAPDH,CNKSR3,PRICKLE1,SVIL,C1R,MOXD1,SNTB1,PLCB1,TNFRSF19 |
| 4.411e-03 | -5.42 | LIAO_HAVE_SOX4_BINDING_SITES | MSigDB lists | LIAO_HAVE_SOX4_BINDING_SITES | 40 | 10 | 17377 | 1707 |
PFKFB4,SEMA3C,SLC22A15,GPRC5B,NRP1,VGLL4,LAMB1,FHOD3,PAM,DKK1 |
| 4.422e-03 | -5.42 | - | gene3d domains | 1.10.1200.10 | 4 | 3 | 8148 | 867 |
ALDH1L2,ALDH1L1,FASN |
| 4.427e-03 | -5.42 | GO_ANGIOGENESIS | MSigDB lists | GO_ANGIOGENESIS | 283 | 42 | 17377 | 1707 |
EFNB2,ACVR1,ID1,FN1,FZD8,ARHGAP22,COL18A1,OVOL2,SLC12A6,EPHB1,NRXN1,PRKCA,TYMP,ITGB3,TSPAN12,DAB2IP,SYK,SLIT2,PDGFRB,NOS3,CYP1B1,VEGFC,VAV3,ADM2,SH2D2A,NR4A1,CALCRL,LEPR,JAM3,FGFR1,GPLD1,WARS,HPSE,PRCP,CCBE1,XBP1,EGFL7,KLF5,BMP4,UNC5B,NRP1,HEY1 |
| 4.433e-03 | -5.42 | GO_PRESYNAPTIC_PROCESS_INVOLVED_IN_SYNAPTIC_TRANSMISSION | MSigDB lists | GO_PRESYNAPTIC_PROCESS_INVOLVED_IN_SYNAPTIC_TRANSMISSION | 109 | 20 | 17377 | 1707 |
DOC2A,SLC6A9,SYT12,SNAP25,APBA1,NRXN1,SYT14,PCLO,SNCA,TRIM9,UNC13B,PPFIA2,LIN7A,PTPRN2,CADPS2,SEPT5,STXBP1,TC2N,RIMS2,SNPH |
| 4.439e-03 | -5.42 | GSE21033_CTRL_VS_POLYIC_STIM_DC_1H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_1H_UP | 170 | 28 | 17377 | 1707 |
GPM6A,MVK,TUBA1A,PNP,KCNQ3,TMEM43,CRIM1,SYT12,NKX3-2,CAPN5,PPFIBP2,VIM,SORBS3,HBE1,JAM3,GAS1,HOPX,CSF1,MPPED2,KIAA1614,LIMCH1,CERS4,SPRY4,SYNGR3,SUSD4,SMYD3,DENND5B,DUSP1 |
| 4.468e-03 | -5.41 | negative regulation of developmental process | biological process | GO:0051093 | 973 | 118 | 17256 | 1658 |
PRKN,DNM3,ID1,FGF13,LDLR,LILRB1,PKP2,GATA3,STAT5B,NTRK3,SEMA6A,SKI,TLR3,ITGB3,BCL6,DAB2IP,WWC2,ZNF365,TLR4,SLIT2,PRKACB,SNAI2,NKX2-1,PHLDB2,PRAME,MEIS2,CSN2,COL4A3,ACVR1C,DCC,NKX3-2,LRRK2,YAP1,VIM,WNT11,SYNJ2BP,SAV1,SMAD3,ENPP1,CXCL10,NRG3,INSIG1,PLK2,GBP1,RBPMS2,WWTR1,ADRB1,PTPRS,SEMA3C,INPP5F,BMPR1A,DLX2,NRP1,TNFSF4,SPART,PPARGC1A,EFNB2,BMPR2,ROBO2,UBASH3B,JDP2,LRP4,CHADL,GAS6,OVOL2,EPHB1,SPINK5,FOXG1,ADGRB2,HOPX,NKX6-1,EFEMP1,IL17D,SEMA4F,CNTN4,ABCA5,GATA2,MYC,BHLHA15,C1QL4,STC2,KIAA0319,ADCY6,BNIP3,FIG4,YBX3,GFI1,ZFP36L2,SPRY2,GPR161,PAK1,TRPM4,BDNF,MSX1,MSTN,RAPGEF2,EFNA3,PRICKLE1,WWC1,MAFB,ZFPM2,DKK1,TRIB3,ID3,ADGRB3,TERT,FBN1,THBS4,AKT3,XBP1,SFMBT1,BMP4,SEMA3A,SIX2,DDIT3,FOXA1,ABCG1,TLL2 |
| 4.476e-03 | -5.41 | GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 124 | 22 | 17377 | 1707 |
TRPM4,GPM6A,SLC3A2,CACNG3,CACNA1E,MCOLN3,RYR2,RASA3,GAS6,ITPR2,CACNB4,NCS1,MCU,MCOLN2,CACNB2,TRPC1,TMEM37,TRPC3,ATP2B4,ATP2B1,CACNA2D1,DENND5B |
| 4.481e-03 | -5.41 | Ectoderm Differentiation | WikiPathways | WP2858 | 143 | 26 | 5312 | 569 |
ABCC4,EDA2R,ELOVL4,FZD4,PTPN13,FZD8,CAP2,PLXNA2,FHL2,PPFIBP2,MAFB,ZNF219,CTNNA2,MYORG,TSKU,SNCA,TCF7L1,EDA,MYC,TFAP2A,TSC22D1,BMPR1A,BMP4,POU2F2,SPRY2,CTNND2 |
| 4.483e-03 | -5.41 | GABRB3 (gamma-aminobutyric acid type A receptor beta3 subunit) | protein interactions | 2562 | 12 | 5 | 17029 | 1718 |
RACK1,PRKCA,AKAP5,GABRB2,MCOLN3 |
| 4.483e-03 | -5.41 | DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12) | protein interactions | 54788 | 12 | 5 | 17029 | 1718 |
KLHL29,HSPA2,DSTN,MYC,MME |
| 4.494e-03 | -5.41 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | 178 | 29 | 17377 | 1707 |
ARHGAP26,LATS2,LRFN5,ANTXR2,SLC40A1,ATF4,TTC39B,GCAT,DSTN,STAT4,BIK,TNFAIP8L2,FHDC1,PRDM1,ARRDC4,TTC28,TIAM2,HERPUD1,BAG3,SIPA1L2,SEMA4F,ATP7B,EHD3,SQLE,SGK1,CERS4,MYO6,SMPDL3A,DIRC2 |
| 4.494e-03 | -5.41 | YYCATTCAWW_UNKNOWN | MSigDB lists | YYCATTCAWW_UNKNOWN | 178 | 29 | 17377 | 1707 |
RWDD2A,GPM6A,MXI1,ID1,LANCL3,TUBA1A,LGALS3,NFIA,PRKAR2B,ATF3,SKAP1,FOXG1,GDPD5,NCS1,NEDD4,IGF1R,KLF12,MFSD2A,MCC,P4HA1,ACVR2A,TSPAN13,LOXL4,SPRY4,SCN3A,MED12L,KCNB2,FILIP1,RAB30 |
| 4.516e-03 | -5.40 | regulation of exocytosis | biological process | GO:0017157 | 190 | 30 | 17256 | 1658 |
DOC2A,EXPH5,PRKN,FER,RAB3B,STXBP5L,SYT12,STXBP6,VAMP8,RAPGEF4,LRRK2,SYT14,PFN2,PCLO,NCS1,SNCA,TRIM9,FGR,UNC13B,GATA2,RAB26,CADPS2,SEPT5,RAB27B,STXBP1,SYK,TC2N,RIMS2,FES,GAB2 |
| 4.517e-03 | -5.40 | GO_REGULATION_OF_FILOPODIUM_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_FILOPODIUM_ASSEMBLY | 34 | 9 | 17377 | 1707 |
GPM6A,DNM3,RHOQ,MYO10,PRKCD,PRKCQ,NRXN1,FNBP1L,PPP1R9A |
| 4.517e-03 | -5.40 | HUMMEL_BURKITTS_LYMPHOMA_UP | MSigDB lists | HUMMEL_BURKITTS_LYMPHOMA_UP | 34 | 9 | 17377 | 1707 |
ID3,SERINC5,TUBA1A,BACH2,TERT,PRKAR2B,LZTS1,FHOD3,MME |
| 4.517e-03 | -5.40 | GO_NADH_METABOLIC_PROCESS | MSigDB lists | GO_NADH_METABOLIC_PROCESS | 34 | 9 | 17377 | 1707 |
PFKFB4,HK1,GAPDH,ENO2,ENO1,PFKFB2,ALDOC,ALDOA,HK2 |
| 4.517e-03 | -5.40 | GO_NEURON_PROJECTION_MEMBRANE | MSigDB lists | GO_NEURON_PROJECTION_MEMBRANE | 34 | 9 | 17377 | 1707 |
GABRG2,EPB41L3,MYO1D,ATF4,ROBO2,AKAP5,WLS,ATP2B1,GABARAPL1 |
| 4.517e-03 | -5.40 | GO_FOREBRAIN_NEURON_DEVELOPMENT | MSigDB lists | GO_FOREBRAIN_NEURON_DEVELOPMENT | 34 | 9 | 17377 | 1707 |
DISC1,ROBO2,RAPGEF2,LHX6,NRP1,SEMA3A,RAC3,SLIT2,FGFR1 |
| 4.521e-03 | -5.40 | human chr5q33.3 | chromosome location | human chr5q33.3 | 36 | 8 | 26185 | 1967 |
EBF1,TTC1,RNF145,LSM11,FABP6,CCNJL,MED7,ZBED8 |
| 4.522e-03 | -5.40 | regulation of transmembrane transport | biological process | GO:0034762 | 534 | 70 | 17256 | 1658 |
SORBS1,CACNG3,HECW2,CACNB4,NOS1AP,KCNAB1,KCNN2,TCAF2,KCNS3,TRPC1,PDE4D,TMEM37,SCN2A,HSPA2,SCN3A,KCNB2,ALG10B,DPP10,KCNIP3,PTPN6,KCNH5,ANK2,SHANK2,JPH1,FGF12,GSTO1,KCND3,ATP1B1,RARRES2,AMIGO1,SNCA,IRS2,ENPP1,CXCL10,PRKCB,KCNG1,GRB10,ATG5,PPARGC1A,MEF2C,KCNV1,SCN5A,UBASH3B,SCN8A,SLC25A27,KCNC4,NEDD4,KCNJ4,LRRC55,CA2,SCN1B,CACNB2,EHD3,TSPAN13,PAK1,RHOQ,GSTM2,KCNQ3,CACNA1E,RYR2,CTTNBP2NL,TRIB3,KCNK15,TERT,HK2,GEM,TESC,CACNA2D1,ATP2B4,STOM |
| 4.524e-03 | -5.40 | GO_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_ION_TRANSMEMBRANE_TRANSPORT | 771 | 98 | 17377 | 1707 |
CACNG3,GRIK2,ATP8A1,MCOLN3,SLC7A2,ITPR2,CACNB4,NCS1,SLC9A7,KCNAB1,KCNN2,CHRNA5,KCNS3,TRPC1,TMEM37,SCN2A,ATP6AP1L,SCN3A,KCNB2,GPM6A,SLC3A2,KCNIP3,ABCC4,LRRC8B,SLC39A8,SFXN4,KCNH5,ATOX1,CHRNA6,ABCC2,ATP1B1,KCND3,SGK2,ASPH,ATP10D,GJC1,SFXN1,SLC39A14,SLC7A1,KCNMB4,ATP7B,KCNG1,BBC3,SLC9B1,DENND5B,PRKAA2,KCNV1,ANO10,TMEM63C,SCN5A,SLC6A9,GABRB2,SCN8A,ATP6V1E2,GABRG2,SLC36A4,GABRR2,SLC1A3,SLC12A6,GAS6,SFXN3,KCNC4,MCU,MCOLN2,KCNJ4,SLC7A11,SLC30A4,SCN1B,CACNB2,SGK3,KCNMB3,SGK1,SLC6A15,ATP2B1,TRPM4,SLC40A1,KCNQ3,SLC37A1,SLC36A1,CACNA1E,GRID1,TTYH2,RASA3,RYR2,PTPRC,KCNK15,GRIK4,TMCO3,SLC7A5,GRIN2D,SLC1A5,TRPC3,SLC16A10,ATP2B4,CACNA2D1,DDIT3,ATP1A3,SLC43A1 |
| 4.532e-03 | -5.40 | GSE10325_BCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_BCELL_VS_MYELOID_DN | 186 | 30 | 17377 | 1707 |
PAK1,MICAL2,RIN2,ALDH2,LGALS3,MPP1,BLVRB,MAFB,KCTD12,CTBP2,CEBPA,COTL1,TNFRSF10C,QPRT,CEBPB,CPVL,NACC2,PELI2,PRKCD,KIAA0513,RNF130,FAR2,PTPRE,TESC,CEBPD,GAB2,RRAGD,CYP1B1,DUSP1,TBC1D8 |
| 4.532e-03 | -5.40 | ZWANG_EGF_INTERVAL_DN | MSigDB lists | ZWANG_EGF_INTERVAL_DN | 186 | 30 | 17377 | 1707 |
PHACTR3,TFCP2L1,KLF8,MXI1,KDM5B,RHOD,ST6GAL1,SPATA13,OVOL2,RNF44,TPD52L1,HOXA1,FAM131B,DKK1,CEBPB,RPL12,CA2,IKZF5,PRKCD,MATN2,SREBF1,KCNS3,AHNAK2,DAB2IP,KLF9,PLD1,BMP4,UNC5B,FNBP1L,SNAI2 |
| 4.532e-03 | -5.40 | GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN | 186 | 30 | 17377 | 1707 |
MOB1B,DMXL2,GCA,LGALS3,PSTPIP2,MPP1,PTPN6,LILRB1,KCTD12,IL13RA1,FAM198B,TMEM170B,NPC2,ASPH,BATF3,WARS,TRPS1,NKX6-1,EPB41L3,HPSE,ZNF697,GNB4,EMILIN2,TSC22D1,RAB31,LIN7A,HS3ST3B1,PTPRE,XKR4,ZNF385A |
| 4.532e-03 | -5.40 | GSE13306_TREG_VS_TCONV_SPLEEN_DN | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_DN | 186 | 30 | 17377 | 1707 |
CXCR5,QSOX1,CARD6,EVL,RNF144A,SLC39A8,PLEKHA5,RAPGEF4,EDEM3,NFE2L1,TJP1,CHSY1,MFSD6,SATB1,TEX9,MBNL2,SLCO3A1,PHLDA2,MCOLN2,AHRR,OTUD1,TGFBR3,MPPED2,PGM2L1,TRPC1,HS3ST3B1,MARCKS,PLTP,ZFP36L2,MED12L |
| 4.532e-03 | -5.40 | GSE3982_MAST_CELL_VS_DC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_DC_DN | 186 | 30 | 17377 | 1707 |
KLF8,FN1,RASAL2,IL15,GALNT12,MCOLN3,GTF2IRD1,PRKAR2B,ATF3,IL13RA1,FAM198B,SEMA6A,PPP2R3A,FSD1,EPCAM,CA2,IGF1R,KMO,RAB31,ACVR2A,MYOM2,CTTN,IQSEC2,TSPAN9,KIF1B,SYK,CSRP2,RBMS2,CKAP4,LAMP3 |
| 4.532e-03 | -5.40 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_UP | 186 | 30 | 17377 | 1707 |
EPB41L5,DBN1,AMOTL1,RUSC2,ELOVL3,ATP6V1E2,GABRG2,KIF5C,SLITRK5,TDRKH,EFHC1,TTLL7,TBC1D16,RAC3,CHST10,CACHD1,KCNMB4,HLF,NAV1,SCRN1,SLC6A15,RAB27B,FBXO27,MYT1,CPE,MID1,ACSM3,HEY1,CNTN1,RNF152 |
| 4.544e-03 | -5.39 | UDP-glycosyltransferase activity | molecular function | GO:0008194 | 148 | 25 | 17224 | 1680 |
CHSY3,CCDC126,GXYLT2,UGT8,GCNT2,B3GALT1,GALNT12,GALNT6,XYLT1,MGAT4B,COLGALT2,GALNT13,GALNT17,CHSY1,MGAT5B,B4GALNT3,GALNT14,GALNT3,GALNT1,GBGT1,MGAT1,B3GALT2,GALNT18,B4GALT7,B4GALT6 |
| 4.546e-03 | -5.39 | GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | MSigDB lists | GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 479 | 65 | 17377 | 1707 |
SORBS1,ID1,AKAP5,ASS1,NPM1,STAT5B,ITPR2,TLR3,AKAP7,PDE4D,SLIT2,PRKACB,FZD1,FER,UROS,LRRK2,ADCY1,PRKAR2B,SNCA,SMAD3,IRS2,ENPP1,EIF4EBP1,GNB4,RGS10,GRB10,PPARGC1A,TNFSF4,RRAGD,MEF2C,GNG12,GABRB2,IPO5,GABRG2,ATP6V1E2,NKX6-1,IGF1R,CA2,GHR,PRKCD,SREBF1,ADCY6,ERRFI1,CHRM3,PAK1,PXN,GSTM2,RHOQ,RAPGEF2,NR4A1,VLDLR,RYR2,PLCB1,BAIAP2,CPEB1,GPLD1,CEBPB,TRIB3,FBN1,TERT,XBP1,RAB31,SH3BP4,TBC1D4,ATP2B4 |
| 4.553e-03 | -5.39 | regulation of filopodium assembly | biological process | GO:0051489 | 41 | 10 | 17256 | 1658 |
TENM1,GPM6A,DNM3,RHOQ,RIPOR2,MYO10,PRKCD,NRP1,FNBP1L,PPP1R9A |
| 4.555e-03 | -5.39 | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | 194 | 31 | 17377 | 1707 |
RIN2,LATS2,ANKRD13D,LCA5,FGF13,DCC,PSTPIP2,EXOC6B,MEF2B,RASA3,NDRG2,NPC2,SNTB1,KIF21B,TTC28,DOCK2,ATP10D,PTPRC,CD37,TECPR1,GPRC5B,RASGRF2,CNKSR3,RGS10,SH3BGRL2,SERPINI1,ZBTB20,ST8SIA1,DIRC2,AMPD1,RRAGD |
| 4.555e-03 | -5.39 | GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP | MSigDB lists | GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP | 194 | 31 | 17377 | 1707 |
ANTXR2,NBL1,ACSL1,ALDH2,FN1,AASS,GCAT,SLC27A2,CRIP2,RASA3,SCD,SESN1,TPK1,BATF3,GNAI1,BEX4,SPNS1,ZNF362,AK1,RPS6KA2,IGF1R,NACC2,AKAP7,BMP1,B3GALT2,PTPRS,FHIT,TSPAN9,MME,CES3,LPP |
| 4.555e-03 | -5.39 | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN | MSigDB lists | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN | 194 | 31 | 17377 | 1707 |
FADS1,QSOX1,LATS2,MOCOS,ACVR1,RHOQ,ALDH2,ERGIC1,ATF4,COL6A2,KDM5B,SLC39A8,ATP8A1,MYO1B,MORC4,RHPN2,FERMT2,GSTO1,NTRK3,GAS6,DDR1,SLCO3A1,IRS2,CDR2L,SPEG,PTPRJ,RALGPS2,PLK2,CPXM2,SVIL,HEY1 |
| 4.564e-03 | -5.39 | CTATGCA,MIR-153 | MSigDB lists | CTATGCA,MIR-153 | 202 | 32 | 17377 | 1707 |
EFNB2,ROBO2,BMPR2,CADM2,MAPK4,CANX,ZFYVE9,DDIT4,TBC1D19,SGK3,PRR16,LRP12,CKAP4,PDLIM7,DPYSL5,KLHL3,TES,EFNA3,RYR2,SNAP25,ZFPM2,PLCB1,SNCA,MKX,SH3BP4,RAI14,SLCO5A1,KLF5,PPARGC1A,OSBPL6,XKR4,LARP1 |
| 4.566e-03 | -5.39 | GO_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | 53 | 12 | 17377 | 1707 |
GSN,MYADM,PRKCD,EPS8,ADD2,SGK1,TMOD2,PFN2,SLIT2,FHOD3,SCIN,SNCA |
| 4.566e-03 | -5.39 | chr6q22 | MSigDB lists | chr6q22 | 53 | 12 | 17377 | 1707 |
SLC35F1,ENPP1,RNF217,AKAP7,WISP3,NCOA7,HS3ST5,KIAA0408,CLVS2,TPD52L1,SMPDL3A,DCBLD1 |
| 4.566e-03 | -5.39 | OUILLETTE_CLL_13Q14_DELETION_DN | MSigDB lists | OUILLETTE_CLL_13Q14_DELETION_DN | 53 | 12 | 17377 | 1707 |
LATS2,SIPA1L2,DDAH1,ENO2,BACE1,BIK,ADAMTS6,IKZF2,DDR1,MLLT3,SCIN,PARP9 |
| 4.575e-03 | -5.39 | coreceptor activity involved in Wnt signaling pathway | molecular function | GO:0071936 | 8 | 4 | 17224 | 1680 |
LRP6,ROR1,PTK7,GPC6 |
| 4.579e-03 | -5.39 | Platelet homeostasis | REACTOME pathways | R-HSA-418346 | 91 | 17 | 10287 | 971 |
PLA2G4A,GNG12,PDE1B,PTPN6,ITPR2,GUCY1A2,KCNMB4,FGR,GNB4,PDE10A,PRKG1,KCNMB3,PRKG2,TRPC3,ATP2B1,ATP2B4,NOS3 |
| 4.583e-03 | -5.39 | GPHA2 (glycoprotein hormone alpha 2) | protein interactions | 170589 | 22 | 7 | 17029 | 1718 |
GPT2,MOXD1,CNTNAP3,FAT1,FRAS1,PCSK5,PLXNA2 |
| 4.585e-03 | -5.39 | MODULE_532 | MSigDB lists | MODULE_532 | 359 | 51 | 17377 | 1707 |
MOCOS,SV2B,ACVR1,ACSL1,FN1,AASS,SLC25A27,BEGAIN,PRDM8,HBE1,MAPK4,SCD,ISYNA1,IL18R1,BAG3,PDE4D,IPCEF1,TBC1D9,LRP3,MED12L,SP140L,KDM5B,TBC1D8B,KLHL4,HOMER2,WDR25,SDC3,OBSCN,PRDM1,AMIGO1,TMEM47,SAV1,FGFR1,RERE,SMAD3,DEXI,SPNS1,CXCL10,GSN,CCBE1,CSF1,MAP2K6,ABI3,WDR19,NCOA7,PLEKHG1,DYNC2LI1,NXPH4,GEM,LARP1,RRAGD |
| 4.587e-03 | -5.38 | Orofacial clefts(PMID:22419666) | GWAS genes | Orofacial clefts(PMID:22419666) | 8 | 5 | 2388 | 399 |
PAK1,FHIT,RASGRF2,BMP6,SH3BP4 |
| 4.596e-03 | -5.38 | regulation of oxidative stress-induced neuron death | biological process | GO:1903203 | 23 | 7 | 17256 | 1658 |
PRKN,RACK1,ATF4,TLR4,TLR6,NCOA7,FZD1 |
| 4.597e-03 | -5.38 | central_nervous_system-chiasm-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-chiasm-glioma-astrocytoma_Grade_I | 8 | 4 | 17385 | 1698 |
RNF130,NACC2,KIAA1549,GNAI1 |
| 4.601e-03 | -5.38 | LRAT | pfam domains | PF04970 | 8 | 4 | 17054 | 1666 |
FAM84B,LRAT,FAM84A,HRASLS |
| 4.607e-03 | -5.38 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_DN | 102 | 19 | 17377 | 1707 |
ATP9A,RBFOX2,ZCCHC24,NFIA,TMTC4,NRN1,ATP1B1,GPC6,MAP1B,NEO1,RGS17,FAT4,PTK7,MPPED2,PLEKHG1,TPM1,PERP,FOXA1,PCSK5 |
| 4.607e-03 | -5.38 | GO_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_FAT_CELL_DIFFERENTIATION | 102 | 19 | 17377 | 1707 |
ZNF516,C1QTNF3,NR4A1,ITGA6,ARID5B,CTBP2,CEBPA,CBY1,RARRES2,BBS9,PLCB1,CEBPB,ADRB1,SREBF1,BNIP3,PPARGC1A,TMEM120B,SMAD6,SNAI2 |
| 4.608e-03 | -5.38 | mTOR signaling pathway | KEGG pathways | hsa04150 | 150 | 26 | 7161 | 730 |
PRKAA2,SLC3A2,SESN2,FZD4,FZD8,DEPTOR,STRADB,ATP6V1E2,CHUK,WNT11,PRKCA,DDIT4,RPS6KA2,IGF1R,PRKCB,EIF4EBP1,AKT3,SLC7A5,TNFRSF1A,SGK1,LRP6,CAB39L,GRB10,RRAGD,FZD1,RNF152 |
| 4.608e-03 | -5.38 | mTOR signaling pathway | KEGG pathways | ko04150 | 150 | 26 | 7161 | 730 |
PRKAA2,SLC3A2,SESN2,FZD4,FZD8,DEPTOR,STRADB,ATP6V1E2,CHUK,WNT11,PRKCA,DDIT4,RPS6KA2,IGF1R,PRKCB,EIF4EBP1,AKT3,SLC7A5,TNFRSF1A,SGK1,LRP6,CAB39L,GRB10,RRAGD,FZD1,RNF152 |
| 4.612e-03 | -5.38 | human chr14q13.3 | chromosome location | human chr14q13.3 | 10 | 4 | 26185 | 1967 |
NKX2-1-AS1,PAX9,NKX2-8,NKX2-1 |
| 4.612e-03 | -5.38 | human chr8q13.3 | chromosome location | human chr8q13.3 | 10 | 4 | 26185 | 1967 |
SLCO5A1,MSC,XKR9,LACTB2-AS1 |
| 4.621e-03 | -5.38 | embryonic limb morphogenesis | biological process | GO:0030326 | 127 | 22 | 17256 | 1658 |
B9D1,INTU,MSX1,RUNX2,RECK,LRP4,SP8,FGFR1,SKI,DKK1,DLX6,FRAS1,WDR19,TBC1D32,TFAP2A,LRP6,HOXD13,BMP4,BMPR1A,DYNC2H1,SHOX2,MAP3K20 |
| 4.621e-03 | -5.38 | embryonic appendage morphogenesis | biological process | GO:0035113 | 127 | 22 | 17256 | 1658 |
B9D1,INTU,MSX1,RUNX2,RECK,LRP4,SP8,FGFR1,SKI,DKK1,DLX6,FRAS1,WDR19,TBC1D32,TFAP2A,LRP6,HOXD13,BMP4,BMPR1A,DYNC2H1,SHOX2,MAP3K20 |
| 4.630e-03 | -5.38 | chondrocyte differentiation | biological process | GO:0002062 | 61 | 13 | 17256 | 1658 |
CREB3L2,RUNX2,BMPR2,BMP4,BMPR1A,CHSY1,SERPINH1,SHOX2,SIX2,FGFR1,COL27A1,GPLD1,MEF2C |
| 4.630e-03 | -5.38 | nucleotide phosphorylation | biological process | GO:0046939 | 61 | 13 | 17256 | 1658 |
AK1,GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,OGDHL,HK2,PGM2L1,AK4,HK1,CMPK2,ENO1 |
| 4.635e-03 | -5.37 | Height(PMID:19396169) | GWAS genes | Height(PMID:19396169) | 3 | 3 | 2388 | 399 |
EFEMP1,ZBTB38,PLAG1 |
| 4.639e-03 | -5.37 | GO_PERINUCLEAR_REGION_OF_CYTOPLASM | MSigDB lists | GO_PERINUCLEAR_REGION_OF_CYTOPLASM | 611 | 80 | 17377 | 1707 |
PLA2G4A,DNM3,AKAP5,GALNT6,KIF5A,MYO1B,VAMP8,NDRG2,RHPN2,PRKCA,RAC3,NCS1,NOS1AP,MAP7,SLC2A12,PACSIN1,TLR4,MYRIP,PRKACB,LAMP3,MEIS2,GAPDH,TGFA,PREX1,PRKAR2B,KCND3,EML1,SNCA,GSN,SH3RF1,ATP7B,LAMB1,ITGA2,PAM,MAGI2,COBL,SEC24D,ATP9A,APBB1,TNFSF13B,HERC5,RASD1,NDFIP2,APBA1,MLC1,TPD52L1,SPINK5,DYNC1I1,GDPD5,NEDD4,SPIRE1,GALNT1,EHD3,STC2,PRKCD,SGK1,MYO6,CKAP4,DISC1,BDNF,RAB3B,USP2,RAPGEF2,VLDLR,WWC1,SNAP25,CLN5,LRAT,CPEB1,CTIF,GALNT3,ICA1,PKN3,CSF1,FAT1,PLD1,DOCK6,PTGES,OSBPL6,STOM |
| 4.644e-03 | -5.37 | LRAT-like_dom | interpro domains | IPR007053 | 8 | 4 | 18492 | 1811 |
FAM84B,LRAT,FAM84A,HRASLS |
| 4.660e-03 | -5.37 | YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) | protein interactions | 7534 | 425 | 60 | 17029 | 1718 |
CGN,MYCBP2,FN1,PAK5,SLK,MLF1,NPM1,LCP2,PRKCA,TPD52L1,DDIT4,EPB41L3,BAG3,ABLIM1,IGF1R,RALGPS2,PPFIBP1,PRKCD,REEP1,SGK1,ERRFI1,ENO1,TESPA1,PNMA2,PAK1,SSH3,DISC1,SYNPO2,MARK1,LCA5,TUBA1A,PFKFB2,NR4A1,PTPN13,LRMP,LRRK2,SPATA13,YAP1,FERMT2,VIM,TNS1,SAV1,MGMT,MAPKAPK2,IRS2,KCNK15,DOCK7,RIPOR2,TERT,WWTR1,RAI14,TBC1D4,MAP3K20,IL9R,SFN,LARP1,BTRC,B4GALT7,MEF2C,MAST1 |
| 4.664e-03 | -5.37 | GO_REGULATION_OF_JNK_CASCADE | MSigDB lists | GO_REGULATION_OF_JNK_CASCADE | 155 | 26 | 17377 | 1707 |
PAK1,TNIK,EDA2R,GRIK2,FZD4,FZD8,PKN1,EPHB1,TNFRSF19,PLCB1,TPD52L1,TLR6,MAGI3,MECOM,TLR3,IGF1R,SH3RF1,DACT1,RAP2A,ERN1,DUSP19,DAB2IP,TLR4,TNFRSF11A,SYK,RASGRP1 |
| 4.664e-03 | -5.37 | GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 155 | 26 | 17377 | 1707 |
SERINC5,RUNX2,TCP11L2,PDE1B,ST6GAL1,RAPGEF4,MCTP2,YPEL2,MSR1,GTF2IRD1,SELL,SDC3,COBLL1,PHACTR2,PRKAR2B,KIF21B,DNER,TLR6,SPIRE1,FBXO32,TRIM34,PRCP,CDH17,SGK3,CERS4,STOM |
| 4.681e-03 | -5.36 | cell adhesion molecule binding | molecular function | GO:0050839 | 483 | 65 | 17224 | 1680 |
CGN,MYO1B,PKP2,COBLL1,CADM2,NRXN1,PRKCA,TNKS1BP1,SNX9,CTNNA2,STK24,EPCAM,BAG3,PPFIBP1,ITGB3,ADGRL1,DAB2IP,CTTN,CPE,ENO1,DBN1,ITGB7,PHLDB2,SLC3A2,COL4A3,CEMIP2,WISP3,TES,PTPN6,NLGN4X,DSP,JAM3,GYPC,ITGA2,ALDOA,FRMD5,TENM1,FN1,PTPRD,SLK,STXBP6,ITGA6,SELL,TJP1,RPL34,EEF2,DSG2,MYO6,FMNL2,SYK,CDH26,FASN,RACK1,BAIAP2,TBC1D2,MPP7,FBN1,THBS4,CDH17,FNBP1L,CDH2,SFN,LARP1,SHTN1,DOCK9 |
| 4.695e-03 | -5.36 | OXFORD_RALB_TARGETS_UP | MSigDB lists | OXFORD_RALB_TARGETS_UP | 8 | 4 | 17377 | 1707 |
IL32,TLN2,SYNGR3,TPM1 |
| 4.695e-03 | -5.36 | GO_POSITIVE_REGULATION_OF_NEURON_MIGRATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_NEURON_MIGRATION | 8 | 4 | 17377 | 1707 |
DAB2IP,SEMA3A,RAPGEF2,SEMA6A |
| 4.695e-03 | -5.36 | NADELLA_PRKAR1A_TARGETS_DN | MSigDB lists | NADELLA_PRKAR1A_TARGETS_DN | 8 | 4 | 17377 | 1707 |
ACTA2,ATL1,CDH2,SNAI2 |
| 4.698e-03 | -5.36 | forearm | COSMIC cancer mutations | forearm | 81 | 16 | 17385 | 1698 |
FER,PTPRD,PTPN13,PTPN21,TNS1,EPHB1,FGFR1,PTPRC,PTPRJ,TERT,PTK7,PTPRN2,PTPRS,MET,TSHR,PTPRE |
| 4.702e-03 | -5.36 | LEUZIPPRFOS | prints domains | PR00042 | 8 | 4 | 4652 | 458 |
ATF3,BATF,JDP2,BATF3 |
| 4.705e-03 | -5.36 | transporter activity | molecular function | GO:0005215 | 1266 | 151 | 17224 | 1680 |
CACNG3,SIDT1,FLVCR2,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,CACNB4,SLCO3A1,SLC9A7,NCS1,KCNAB1,KCNN2,SLC16A2,SLC22A18,SLC10A7,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,COG3,PLTP,GPM6A,KCNIP3,SLC3A2,ABCC4,SLC9C1,ATOX1,JPH1,SLC25A28,ABCC2,KCND3,SFXN1,SPNS1,SLC7A1,KCNMB4,ATP7B,MFSD4A,SLC9B1,KCNV1,SV2B,SCN5A,TMEM63C,GABRB2,SCN8A,SLC25A27,ATP6V1E2,SLC36A4,SLC1A3,MLC1,MCOLN2,SLC30A4,SLC7A11,ABCA5,CACNB2,PRELID2,PRELID1,LRP6,SLC16A9,NIPAL2,SLCO4C1,FAM155A,NDUFA4L2,SLC37A1,KCNQ3,SLC36A1,PLEKHA8,SLC27A2,VLDLR,RYR2,TTYH2,CALCRL,NPC2,STEAP1,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,CDH17,TRPC3,OSBPL6,SLC7A2,SLC19A2,SLC22A17,CHRNA5,STARD4,FAM155B,SCN2A,ATP6AP1L,KCNB2,SCN3A,LRRC8B,KCNH5,SFXN4,SLC39A8,CHRNA6,ATP1B1,ATP10D,GJC1,SLC39A14,KPNA3,ASIC1,KCNG1,DISP1,DENND5B,ANO10,SERINC5,PLSCR4,SLC6A9,ATP9A,IPO5,GABRG2,GAS6,SLC12A6,GABRR2,SFXN3,KCNC4,SLC35G2,MCU,SLC35F1,LRRC55,KCNJ4,SCN1B,KCNMB3,SLC6A15,SLC45A3,ATP2B1,TRPM4,SLC40A1,CACNA1E,GRID1,RASA3,ATP11A,MFSD9,OSBPL5,SLC7A5,SLC18B1,SLCO5A1,GRIN2D,SLC22A15,SLC1A5,SLC16A10,CACNA2D1,ATP2B4,ABCG1,ATP1A3,SLC43A1 |
| 4.706e-03 | -5.36 | V$AML1_Q6 | MSigDB lists | V$AML1_Q6 | 251 | 38 | 17377 | 1707 |
INPPL1,SLC6A9,DNM3,RASAL2,OTOGL,JDP2,SCN8A,SLC12A6,PRRG4,TACC2,DACT1,TMEM86A,TSPAN9,COL9A2,NKX2-1,ITGB7,MEIS2,PXN,NR4A1,FOXN3,MSRB3,SLITRK5,PRICKLE1,VIM,ARHGAP32,BATF,BATF3,DKK1,ENTPD1,ID3,ARHGAP21,TMEM117,TPM1,DNHD1,TNFSF4,KIF1B,RAB30,TLL2 |
| 4.706e-03 | -5.36 | V$AML1_01 | MSigDB lists | V$AML1_01 | 251 | 38 | 17377 | 1707 |
INPPL1,DNM3,SLC6A9,RASAL2,OTOGL,JDP2,SCN8A,SLC12A6,PRRG4,TACC2,DACT1,TMEM86A,TSPAN9,COL9A2,NKX2-1,ITGB7,PXN,MEIS2,NR4A1,FOXN3,SLITRK5,PRICKLE1,MSRB3,VIM,ARHGAP32,BATF,DKK1,BATF3,ENTPD1,ARHGAP21,ID3,TMEM117,TPM1,DNHD1,TNFSF4,KIF1B,RAB30,TLL2 |
| 4.706e-03 | -5.36 | V$HNF4ALPHA_Q6 | MSigDB lists | V$HNF4ALPHA_Q6 | 251 | 38 | 17377 | 1707 |
MXI1,CHCHD7,RHOBTB1,PLAG1,CADM2,DOCK3,SATB1,NOVA1,SEMA6A,PCDH7,LRRN1,SEC16B,COL25A1,DACT1,SRGAP1,TSC22D1,SHF,PACSIN1,TMEM132E,NDUFA4L2,ATL1,RAPGEF4,PRDM1,LHPP,F12,INHBC,DOCK7,PLAGL1,PMEPA1,HPGD,TMOD2,ZBTB20,SPRY4,NRP1,TPM1,PPARGC1A,HOXB9,MAPK10 |
| 4.706e-03 | -5.36 | REACTOME_SIGNALING_BY_PDGF | MSigDB lists | REACTOME_SIGNALING_BY_PDGF | 117 | 21 | 17377 | 1707 |
COL9A3,COL6A2,PDE1B,COL4A3,NR4A1,COL4A4,ADCY1,COL4A5,PRKAR2B,CHUK,STAT5B,ITPR2,PRKCA,TRIB3,THBS4,AKT3,PRKCD,ADCY6,COL9A2,PDGFRB,PRKACB |
| 4.718e-03 | -5.36 | GLI1 (GLI family zinc finger 1) | protein interactions | 2735 | 65 | 14 | 17029 | 1718 |
PRKAA2,IFT81,MYC,RPL21,XBP1,P4HA1,NPM1,ZIC2,CHUK,RACK1,BTRC,KIAA1211,ZIC1,GNAI1 |
| 4.741e-03 | -5.35 | positive regulation of transporter activity | biological process | GO:0032411 | 97 | 18 | 17256 | 1658 |
GSTM2,ANK2,RYR2,GSTO1,ATP1B1,SGK2,NOS1AP,LRRC55,CACNB2,PRKCD,EHD3,SGK3,SGK1,SYNGR3,TESC,HSPA2,CACNA2D1,ALG10B |
| 4.747e-03 | -5.35 | odontogenesis | biological process | GO:0042476 | 112 | 20 | 17256 | 1658 |
BCL11B,ENAM,SCN5A,MSX1,RUNX2,ITGA6,LRP4,ACVR2B,ID3,CA2,EDA,LAMB1,PAM,LRP6,TUFT1,BMP4,BMPR1A,DLX2,PAX9,PERP |
| 4.747e-03 | -5.35 | neurotransmitter secretion | biological process | GO:0007269 | 112 | 20 | 17256 | 1658 |
DOC2A,SLC6A9,SYT12,PPFIA4,SNAP25,SYT14,APBA1,NRXN1,PCLO,TRIM9,UNC13B,PPFIA2,PTPRN2,LIN7A,CADPS2,SEPT5,STXBP1,TC2N,RIMS2,SNPH |
| 4.747e-03 | -5.35 | signal release from synapse | biological process | GO:0099643 | 112 | 20 | 17256 | 1658 |
DOC2A,SLC6A9,SYT12,PPFIA4,SNAP25,SYT14,APBA1,NRXN1,PCLO,TRIM9,UNC13B,PPFIA2,PTPRN2,LIN7A,CADPS2,SEPT5,STXBP1,TC2N,RIMS2,SNPH |
| 4.747e-03 | -5.35 | developmental growth involved in morphogenesis | biological process | GO:0060560 | 112 | 20 | 17256 | 1658 |
EPB41L5,BDNF,KDM5B,YAP1,WNT11,DDR1,MAP1B,SH3GL2,PTK7,CSF1,FLRT3,LRP6,HOXD13,BMP4,NRP1,SEMA3A,MAGI2,SPRY2,SLIT2,COBL |
| 4.754e-03 | -5.35 | GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_UP | MSigDB lists | GSE26928_EFF_MEM_VS_CENTR_MEM_CD4_TCELL_UP | 163 | 27 | 17377 | 1707 |
NDUFA4L2,PRKAA2,BCL7A,DYRK3,EVL,MARK1,EML6,AASS,PRDM13,C1orf226,FHL2,HIP1,ATP1B1,C1orf174,FKBP11,PCDH7,HOPX,TMEM132B,GALNT1,EOMES,MFSD9,NOVA2,WWTR1,SLCO5A1,PTPRS,ZNF365,GAB2 |
| 4.754e-03 | -5.35 | GO_DIVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_DIVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 163 | 27 | 17377 | 1707 |
TRPM4,SLC40A1,GPM6A,SLC3A2,CACNG3,SLC39A8,CACNA1E,MCOLN3,RYR2,RASA3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,SLC39A14,SLC30A4,CACNB2,TRPC1,TMEM37,NIPAL2,TRPC3,ATP2B4,CACNA2D1,ATP2B1,DENND5B |
| 4.754e-03 | -5.35 | GCM_MAP4K4 | MSigDB lists | GCM_MAP4K4 | 163 | 27 | 17377 | 1707 |
FADS1,TNIK,BMPR2,PTPRD,MYO10,AGPAT4,LRP4,IPO5,PREX1,ZNF565,TTYH2,ABHD6,PEAK1,SPIRE1,PLEKHB1,CHST10,MTUS1,IL17D,RNF141,ARHGAP21,GPRC5B,TMOD2,TANC2,KIF1B,FMNL2,BTRC,GAB2 |
| 4.760e-03 | -5.35 | CAHOY_NEURONAL | MSigDB lists | CAHOY_NEURONAL | 95 | 18 | 17377 | 1707 |
BCL11B,SV2B,CACNG3,ENO2,SIDT1,PRSS12,CLSTN2,GABRG2,SATB2,PRDM8,DYNC1I1,BCL11A,PPFIA2,KIAA0319,PGM2L1,COL19A1,STXBP1,MEF2C |
| 4.760e-03 | -5.35 | ATTACAT,MIR-380-3P | MSigDB lists | ATTACAT,MIR-380-3P | 95 | 18 | 17377 | 1707 |
BDNF,KLHL4,FGF12,SNAP25,ZFPM2,NRXN1,FNDC3A,HERC6,TRPS1,HTR7,PRKCB,PGM2L1,SLC6A15,ZBTB20,FIGN,C15orf41,MLLT3,MEF2C |
| 4.771e-03 | -5.35 | FERM_M | pfam domains | PF00373 | 47 | 11 | 17054 | 1666 |
FRMPD3,EPB41L5,EPB41L3,FARP1,PLEKHH2,MYO10,PTPN13,PTPN21,FERMT2,TLN2,FRMD5 |
| 4.783e-03 | -5.34 | Norepinephrine Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-181430 | 18 | 6 | 10287 | 971 |
PPFIA4,MAOA,SNAP25,UNC13B,STXBP1,PPFIA2 |
| 4.783e-03 | -5.34 | cGMP effects | REACTOME pathways | R-HSA-418457 | 18 | 6 | 10287 | 971 |
PRKG2,KCNMB4,PDE1B,PDE10A,KCNMB3,PRKG1 |
| 4.788e-03 | -5.34 | human chr8q12.1 | chromosome location | human chr8q12.1 | 29 | 7 | 26185 | 1967 |
RPS20,TOX,CHCHD7,CA8,FAM110B,XKR4,PLAG1 |
| 4.788e-03 | -5.34 | human chr6q14.1 | chromosome location | human chr6q14.1 | 29 | 7 | 26185 | 1967 |
RWDD2A,SH3BGRL2,LCA5,MYO6,TENT5A,ELOVL4,FILIP1 |
| 4.791e-03 | -5.34 | molecular adaptor activity | molecular function | GO:0060090 | 188 | 30 | 17224 | 1680 |
VAV3,SH3BP2,SORBS1,SKAP2,GRB14,SH2D2A,ANK2,EPS8,HIP1,JCHAIN,GAS6,RACK1,ARRDC4,SKAP1,DSP,COL14A1,BAIAP2,CHN1,ERG28,CHN2,MAP1A,MPP7,FLRT3,DUSP19,SHF,COL19A1,DAB2IP,AFAP1L2,GRB10,GAB2 |
| 4.804e-03 | -5.34 | ER-nucleus signaling pathway | biological process | GO:0006984 | 35 | 9 | 17256 | 1658 |
ARHGEF10L,ASNS,ATF4,INSIG1,WFS1,XBP1,ATF3,DDIT3,HERPUD1 |
| 4.805e-03 | -5.34 | INSL5 (insulin like 5) | protein interactions | 10022 | 52 | 12 | 17029 | 1718 |
COL6A2,TUBA1A,CEMIP2,CNTNAP3,PLXDC2,PLXNA2,AMIGO1,MOXD1,COL14A1,SEMA6A,CHST10,PCSK5 |
| 4.805e-03 | -5.34 | JUND (JunD proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 3727 | 52 | 12 | 17029 | 1718 |
SMAD3,JDP2,ARHGAP22,BCL6,NFE2L1,ATF3,PRKCQ,CREB5,BATF,TPM1,DDIT3,BATF3 |
| 4.812e-03 | -5.34 | Actb (actin, beta) | protein interactions | 11461 | 182 | 30 | 17029 | 1718 |
DBN1,CGN,PHLDB2,MYO10,CAP2,TES,MYO1B,TJP1,SNCA,GNAI1,PLS3,GSN,ABLIM1,ARHGAP21,CPNE2,DOCK7,FCHO2,DSG2,RAI14,SRGAP1,SVIL,LIMCH1,CTTN,MYO6,TPM1,RRAS2,STON2,COBL,KIAA1211,STOM |
| 4.816e-03 | -5.34 | BURTON_ADIPOGENESIS_PEAK_AT_0HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_0HR | 60 | 13 | 17377 | 1707 |
RAB11FIP5,VEGFC,TRIB3,CSF1,ACTA2,RASL11B,MARCKS,PCK2,TPM1,PDGFRB,GAS1,DDIT3,F3 |
| 4.823e-03 | -5.33 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP | 171 | 28 | 17377 | 1707 |
MYCBP2,CD55,RHOQ,EVL,TUBA1A,ZNF395,CKAP2,ST6GAL1,ARID5B,SKAP1,DENND3,IRS2,ENTPD1,CD37,ABLIM1,IKZF3,BACH2,CDC14B,BACE2,MYC,HK2,PIK3C2B,MARCKS,SP140,RRAS2,DDIT3,ATP2B1,DOCK9 |
| 4.823e-03 | -5.33 | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN | 171 | 28 | 17377 | 1707 |
ARAP2,ACSL1,IL15,REL,RAPGEF2,STAT4,LDLR,TTYH2,ZIC2,ATF3,BATF,HERC6,ISG20,GALNT3,CXCL10,INSIG1,ZNF697,GBP1,MFSD2A,ERN1,AFAP1L2,HS3ST3B1,GEM,CMPK2,RASGRP1,RAB30,DUSP1,LAMP3 |
| 4.823e-03 | -5.33 | GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_UP | MSigDB lists | GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_UP | 171 | 28 | 17377 | 1707 |
LPCAT2,ELOVL7,LMCD1,PRRG1,AMIGO1,ZBBX,EPHB1,LCP2,PALLD,DNER,DDX60L,PPP1R9A,TRIB3,TMCO3,CXCL10,KCNJ4,OTUD1,PRTFDC1,LRRN1,CCBE1,PLK2,MAGEA3,KCNS3,NAP1L3,MAGEA6,MYT1,GATM,PGBD5 |
| 4.828e-03 | -5.33 | TYR_PHOSPHATASE_dom | interpro domains | IPR000387 | 81 | 16 | 18492 | 1811 |
PTPRC,SSH3,PTPRJ,DUSP8,PTPRU,CDC14B,PTPRD,PTPN6,PTPN13,PTPN21,DUSP19,PTPRN2,DUSP9,PTPRS,PTPRE,DUSP1 |
| 4.854e-03 | -5.33 | PCDH12 (protocadherin 12) | protein interactions | 51294 | 17 | 6 | 17029 | 1718 |
PTPRS,PCDH10,CELSR1,DCBLD1,PCDH7,TMTC4 |
| 4.854e-03 | -5.33 | KCNB1 (potassium voltage-gated channel subfamily B member 1) | protein interactions | 3745 | 17 | 6 | 17029 | 1718 |
KCNV1,SNAP25,PTPRE,KCNG1,KCNB2,KCNS3 |
| 4.854e-03 | -5.33 | FGD6 (FYVE, RhoGEF and PH domain containing 6) | protein interactions | 55785 | 17 | 6 | 17029 | 1718 |
NPM1,CGN,CBY1,ACVR1,PLK2,PDGFRB |
| 4.854e-03 | -5.33 | TGACCTTG_V$SF1_Q6 | MSigDB lists | TGACCTTG_V$SF1_Q6 | 227 | 35 | 17377 | 1707 |
PHACTR3,LRFN5,SCN5A,KIF5A,XYLT1,RGS7,FAM81A,DNER,SLC9A7,PCDH7,TUBB4A,RAB11FIP5,CA2,CACNB2,FAM155B,RAPGEF5,RIN2,LCA5,MGST3,PANK1,GDPD1,OGDHL,ADCY1,WWC1,SDK1,ATP1B1,MAP1B,GABARAPL1,DEXI,SH3GL2,ALDOA,NXPH4,DIRAS1,SNPH,MEF2C |
| 4.861e-03 | -5.33 | ONKEN_UVEAL_MELANOMA_UP | MSigDB lists | ONKEN_UVEAL_MELANOMA_UP | 728 | 93 | 17377 | 1707 |
ACSL1,FGF13,RNF144A,RBFOX2,RGS20,ASS1,COL18A1,KCTD12,ITPR2,PRKCA,FKBP11,PCDH7,CYP51A1,TYMP,RPS6KA2,TM9SF2,TACC2,SLC22A18,REEP1,NDUFB8,CTTN,MET,PLTP,CD55,MEIS2,WLS,ANK2,ADCY1,FEZ1,EFHC1,COTL1,KCND3,TBC1D16,TTC28,ASPH,WARS,SMAD3,P4HA2,WWTR1,PAM,INPP4B,BDH2,AHNAK2,P4HA1,LZTS1,SERINC5,CELSR1,LGALS3,SEC24D,ZHX3,CHCHD7,TBC1D1,ATP9A,ITGA6,SSX1,SCD,SFXN3,PFN2,FAM174B,SEL1L3,PGAP1,PHLDA2,FRY,PDE10A,OPN3,TSC22D1,SGK1,MED7,FAR2,MYO6,ZFP36L2,ATP2B1,CEBPD,FADS1,VLDLR,RAPGEF4,FASN,AK4,C1R,CDC42BPA,BAIAP2,PTPRC,NACC2,HK2,RAI14,PCGF2,RAB31,LAPTM4B,SQLE,GEM,LARP1,STOM,DOCK9 |
| 4.865e-03 | -5.33 | endocardial cushion morphogenesis | biological process | GO:0003203 | 29 | 8 | 17256 | 1658 |
MSX1,ACVR1,HEYL,DCHS1,BMP4,BMPR1A,SNAI2,HEY1 |
| 4.872e-03 | -5.32 | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_DN | 179 | 29 | 17377 | 1707 |
ARAP2,EHHADH,PNRC1,IL15,DNAJC6,C3orf52,TTYH2,HERC5,FERMT2,ATF3,HERC6,PRRG4,WARS,EPDR1,HMGCS1,PMAIP1,ENTPD7,GBP1,AKT3,STARD4,C1orf21,RALGAPA2,SLCO5A1,GRB10,TSPAN13,CMPK2,ETV1,CKAP4,RAB30 |
| 4.872e-03 | -5.32 | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_UP | 179 | 29 | 17377 | 1707 |
RPS20,BCL7A,RPL26,EVL,SIDT1,ST6GAL1,RPL21,ARID5B,SETBP1,NPM1,CR2,DDR1,RPL34,BCL11A,SMAD3,EEF2,RPL28,BACH2,KIAA0355,RPS11,OPN3,TSPAN13,PIK3C2B,RRAS2,ESD,NR3C2,SP140L,PKIA,RPS13 |
| 4.882e-03 | -5.32 | V$E4F1_Q6 | MSigDB lists | V$E4F1_Q6 | 268 | 40 | 17377 | 1707 |
DNM3,MRC2,CCDC148,ID1,RHOBTB1,FAM117B,GRK6,SEZ6L2,FSTL5,NUMBL,MAP1A,PDZD8,DACT1,ALDOC,FLRT3,EIF1,TRPC1,TSPAN13,PPP2R2B,SYNGR3,ARL4D,RBMS2,DUSP1,NR6A1,SH2D2A,NR4A1,ANK2,ELMOD1,CALCRL,PNMA6A,SATB2,ATP10D,ZNF711,RANBP2,PDLIM3,ADAMTS3,C1orf21,GEM,PPARGC1A,FOXA1 |
| 4.884e-03 | -5.32 | GO_POTASSIUM_CHANNEL_COMPLEX | MSigDB lists | GO_POTASSIUM_CHANNEL_COMPLEX | 88 | 17 | 17377 | 1707 |
KCNV1,KCNIP3,KCNQ3,AMIGO1,KCND3,SNAP25,KCNC4,NOS1AP,KCNJ4,KCNMB4,KCNAB1,KCNG1,KCNS3,KCNMB3,DLG2,CTTN,KCNB2 |
| 4.884e-03 | -5.32 | GO_PDZ_DOMAIN_BINDING | MSigDB lists | GO_PDZ_DOMAIN_BINDING | 88 | 17 | 17377 | 1707 |
GNG12,GRIK2,FZD4,CRIM1,RAPGEF2,FZD8,PLEKHA1,APBA1,SNTB1,BAIAP2,KCNJ4,TGFBR3,ADRB1,ACVR2A,ATP2B1,ATP2B4,FZD1 |
| 4.884e-03 | -5.32 | KANG_IMMORTALIZED_BY_TERT_UP | MSigDB lists | KANG_IMMORTALIZED_BY_TERT_UP | 88 | 17 | 17377 | 1707 |
PPP1R3D,BDNF,COL6A2,SKAP2,MAPK4,DOCK2,LEPR,PCDH7,DKK1,P4HA2,LAMB1,TFAP2A,CLMN,BNIP3,ZNF460,ENO1,CACNA2D1 |
| 4.889e-03 | -5.32 | protein secretion | biological process | GO:0009306 | 151 | 25 | 17256 | 1658 |
RAB3B,PNP,WLS,RAPGEF4,TNFSF13B,LILRB1,GATA3,ACVR2B,CANX,LCP2,TLR6,PCLO,ILDR2,CBLN1,RAB11FIP5,MCOLN2,RAB26,PTPRN2,STEAP3,POU2F2,ARL4D,TLR4,IL1RAP,RIMS2,PCSK5 |
| 4.904e-03 | -5.32 | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_DN | 187 | 30 | 17377 | 1707 |
VEGFC,PPP1R3D,MID2,GDAP1,RIN2,MYCBP2,KCNIP3,PTPN6,FOXN3,CD276,BIK,PREX1,ST6GALNAC3,TNS1,DENND3,TEX9,BBS9,HECTD2,EFEMP1,TMEM86A,CDH17,ATRNL1,TOX,INPP5F,GEM,POU2F2,GFI1,TBC1D4,TNFRSF11A,FRMD5 |
| 4.904e-03 | -5.32 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN | 187 | 30 | 17377 | 1707 |
EPB41L5,TCTN2,DOCK1,MPP1,GPR65,STAT4,VAMP8,SPATA13,SLC25A28,ATF3,PRDM1,SAV1,ASPH,KHDRBS2,STK24,BATF3,SMAD3,CXCL10,TIFA,GYPC,SRD5A3,CAB39L,TSPAN13,CMPK2,ETV1,SNX10,BARX1,PTGES,TBC1D8,B4GALT6 |
| 4.904e-03 | -5.32 | GSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_UP | MSigDB lists | GSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_UP | 187 | 30 | 17377 | 1707 |
CXCR5,CGN,ALOX5AP,BTNL9,SCN8A,GJB2,PPFIBP2,TNFSF13B,PLXNA2,TTC22,ATP1B1,COLEC10,PALLD,NUDT12,RAC3,C4BPB,BEX4,IFT81,GRIK4,CCBE1,FAM168A,BMP1,GRIP1,FAM149A,DIRAS1,TNFRSF17,HOXB9,SFN,ATP1A3,CYP1B1 |
| 4.904e-03 | -5.32 | GSE14350_IL2RB_KO_VS_WT_TEFF_DN | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TEFF_DN | 187 | 30 | 17377 | 1707 |
GPT2,TBKBP1,GNG12,SLC3A2,SH3BP2,PRSS16,PRDM1,TMEM170B,DENND3,NEDD4,CEBPB,ENTPD1,ASNS,MYADM,SOAT2,MGAT1,TACC2,PELI2,XBP1,HPGD,NXPH4,PROS1,CMPK2,RRAS2,SEPT3,GFI1,NKX2-8,NEB,SLC16A10,PSPH |
| 4.904e-03 | -5.32 | GSE3982_MAC_VS_NKCELL_UP | MSigDB lists | GSE3982_MAC_VS_NKCELL_UP | 187 | 30 | 17377 | 1707 |
GPR63,FER,RGS16,GNG12,ACSL1,LRRC8B,GALNT12,HEBP1,MGST3,ARHGAP22,GTF2IRD1,KCTD12,TNS1,SCD,DOCK3,PPP2R3A,QPRT,CYP51A1,BEX4,EPB41L3,GSN,NACC2,P4HA2,CSF1,WWTR1,AHNAK2,PCOLCE2,STXBP1,FNBP1L,GATM |
| 4.904e-03 | -5.32 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | 187 | 30 | 17377 | 1707 |
RPS20,BCL7A,RUNX2,ALOX5AP,SIDT1,CRIM1,DSTN,ATP8A1,SETBP1,COBLL1,GAS6,EPHB1,RGS7,SEL1L3,IL18R1,FKBP11,BCL11A,MAPKAPK2,MAP1A,SLC7A11,TM9SF2,DACT1,MAP2K6,SLC7A5,OPN3,AHNAK2,PTPRS,NRP1,PTPRCAP,TBC1D4 |
| 4.904e-03 | -5.32 | GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 187 | 30 | 17377 | 1707 |
RIN2,ITGB7,SORBS1,TTC39B,SIDT1,CRIM1,ITGA6,BNIP3L,SELL,MSRB3,SEL1L3,SESN1,INPP1,SLC46A3,HERPUD1,HOPX,ENPP1,FBXO32,MYADM,IGF1R,CDC14B,AKAP7,GPR160,RAB31,DBP,POU2F2,PCK2,RAPGEF5,CSRP2,ATP2B1 |
| 4.904e-03 | -5.32 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | 187 | 30 | 17377 | 1707 |
TNIK,ERGIC1,RHOD,FOXN3,ITGA6,FASN,GSTO1,SCD,NTRK3,IKZF2,SCIN,CYP51A1,HMGCS1,IDI1,EOMES,INSIG1,PLAGL1,STARD4,NCOA7,PGM2L1,LIN7A,MAOA,SQLE,TSPAN13,IPCEF1,PACSIN1,NRP1,TBC1D4,MID1,HMGCR |
| 4.914e-03 | -5.32 | response to ketone | biological process | GO:1901654 | 183 | 29 | 17256 | 1658 |
PRKAA2,MSTN,ADCY1,ASS1,YAP1,NTRK3,ABCC2,DDIT4,GNAI1,FOXP2,TGFBR3,FBXO32,EIF4EBP1,DSG2,SREBF1,ADCY6,HOXD13,OXTR,KLF9,TNFSF4,ERRFI1,PCK2,SLIT2,KIF1B,SMYD3,PSPH,ATP2B1,LARP1,DUSP1 |
| 4.920e-03 | -5.31 | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | 195 | 31 | 17377 | 1707 |
MID2,BDNF,ACSL1,SKAP2,LGALS3,IL15,SH2D2A,SLC27A2,DSTN,PLEKHA5,GPR65,SLK,EPS8,IGF2BP2,PRDM1,BATF,SATB1,TEX9,SLCO3A1,IL18R1,NEDD4,HERPUD1,HOPX,PLS3,AHRR,SLC7A11,GTF2F2,GEM,TNFSF4,GATM,LPP |
| 4.935e-03 | -5.31 | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | REACTOME pathways | R-HSA-112314 | 146 | 24 | 10287 | 971 |
GNG12,CACNG3,AKAP5,GRIK2,GABRB2,ADCY1,GABRG2,CHRNA6,GABRR2,PRKCA,PLCB1,GNAI1,GRIK4,KCNJ4,RPS6KA2,CHRNA5,PRKCB,RASGRF2,GNB4,ADCY6,GRIP1,GRIN2D,MYO6,PRKACB |
| 4.947e-03 | -5.31 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 1361 | 162 | 17377 | 1707 |
EXPH5,GRIK2,VAMP8,GATA3,LILRB1,NPM1,SNX9,NUP62CL,RAC3,TRPS1,ADPRHL1,RND2,SEC16B,PMAIP1,RAP2A,RAB26,LIN7A,TMED9,CTTN,COG3,PACSIN1,TLR4,MYRIP,TBC1D8,GDAP1,KCNIP3,WLS,ANK2,EXOC6B,LRRK2,ACVR2B,PLEKHA1,TNFRSF1A,BBC3,DIRAS1,APBA2,CHMP4C,PCSK5,STXBP5L,RHOBTB1,SEC24D,TBC1D1,ATP6V1E2,RASL11B,APBA1,MLC1,BBS9,TTC30B,PGAP1,SPIRE1,RPL13A,PDZD7,CACNB2,RPS11,FRAS1,CADPS2,LMAN2,STXBP1,RIMS2,RPS23,SNX7,RPL26,RHOQ,PNP,TBC1D8B,PLEKHA8,VLDLR,RAPGEF4,TTC30A,RYR2,CALCRL,STRADB,PEX5L,HERPUD1,TBC1D2,VPS37D,RPL28,WDR19,HK2,RAB31,PTPRN2,CDH2,TESC,SMYD3,SIX2,SCAMP1,RHOD,AKAP5,MSR1,PKP2,CANX,NRXN1,LCP2,PCLO,CBLN1,TBC1D30,ZFYVE9,REEP1,BCL6,STEAP3,MARCKS,POU2F2,ARL4D,RPL26L1,RAB27B,SNX10,KCNB2,RPS13,PHLDB2,TRAM1L1,SYNJ2BP,ATP1B1,RAB38,TBC1D16,RANBP2,IFT81,KPNA3,PRKCB,ITGA2,RAB30,RPS20,TSPAN15,IPO5,ARL2,RASD1,GAS6,TSPAN17,NEDD4,RPL34,RAB11FIP5,EHD3,RASD2,TRIM3,PRKG2,DYNC2H1,MYO6,TBC1D9,RRAS2,SYK,LCA5,RAB3B,RAB6B,RPL21,ZDHHC15,PRICKLE1,AGAP2,TLR6,ILDR2,HOMER3,RERE,RPL12,MYADM,TERT,RND3,XBP1,MCC,RPL4,HK1,RPS12,GEM,TBC1D4,ABCG1 |
| 4.951e-03 | -5.31 | GAJATE_RESPONSE_TO_TRABECTEDIN_UP | MSigDB lists | GAJATE_RESPONSE_TO_TRABECTEDIN_UP | 67 | 14 | 17377 | 1707 |
CARS,GSN,GARS,ASNS,TUBA1A,MSMO1,VLDLR,CBS,C1R,ATF3,PROS1,PCK2,CPE,CSRP2 |
| 4.960e-03 | -5.31 | skin-hand-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-hand-carcinoma-squamous_cell_carcinoma | 414 | 57 | 17385 | 1698 |
PHACTR3,MYCBP2,FARP1,ADAL,TCTN2,FN1,UBASH3B,GALNT6,ADD2,COL4A5,CADM2,ADAMTS6,SEZ6L2,DNER,DOK5,HMCN1,ZFYVE9,COL22A1,KCNJ4,KIAA1958,FRY,UNC13B,CNTN4,TMEM86A,TRIM3,MET,SEPT3,MYT1,UNC5C,SLC40A1,MYLK3,SLITRK2,DCC,SLC39A8,SHANK2,PREX1,ZNF565,STRADB,CR2,PEX5L,ATOH1,INTS6,AMDHD1,FGFR1,MMP15,PTPRC,DPY19L2,PLEKHH2,MYADM,PDLIM3,ATP7B,ZNF214,LRRIQ3,INPP4B,ZNF704,HGF,UNC5B |
| 4.964e-03 | -5.31 | Ser-Thr/Tyr_kinase_cat_dom | interpro domains | IPR001245 | 133 | 23 | 18492 | 1811 |
EPHA3,FGFR4,TYRO3,FER,TNK2,ACVR1C,NTRK3,ROR1,EPHB1,DDR1,FRK,FGFR1,FGR,IGF1R,PTK7,MAP3K21,BMPR1A,EPHB6,MET,MAP3K20,SYK,PDGFRB,FES |
| 4.977e-03 | -5.30 | GO_REGULATION_OF_NEUROTRANSMITTER_SECRETION | MSigDB lists | GO_REGULATION_OF_NEUROTRANSMITTER_SECRETION | 47 | 11 | 17377 | 1707 |
KCNMB4,UNC13B,SYT12,LRRK2,SEPT5,KCNC4,STXBP1,PFN2,PPP1R9A,MEF2C,SNCA |
| 4.978e-03 | -5.30 | GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN | 148 | 25 | 17377 | 1707 |
BDNF,NBL1,SIDT1,IGFBP6,GABRB2,SYT12,EFHC2,MCOLN3,FHDC1,GAS6,SATB1,KBTBD11,PGAP1,GAS1,GPR150,EPDR1,GBGT1,FKBP9,TMEM237,EOMES,GRHL1,TRPC3,PSPH,SNX7,PHC1 |
| 4.994e-03 | -5.30 | REACTOME_PLATELET_HOMEOSTASIS | MSigDB lists | REACTOME_PLATELET_HOMEOSTASIS | 74 | 15 | 17377 | 1707 |
PLA2G4A,GNG12,FGR,KCNMB4,PDE1B,PDE10A,GNB4,PTPN6,PRKG1,KCNMB3,PRKG2,ITPR2,GUCY1A2,TRPC3,NOS3 |
| 4.994e-03 | -5.30 | GO_RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | GO_RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 74 | 15 | 17377 | 1707 |
ARHGEF10L,VAV3,FARP1,ARHGEF11,DOCK1,RASGRF2,MCF2L2,MCF2L,PLEKHG1,PREX1,SPATA13,OBSCN,DOCK2,TIAM2,ARHGEF26 |
| 4.998e-03 | -5.30 | Wnt-activated receptor activity | molecular function | GO:0042813 | 23 | 7 | 17224 | 1680 |
LRP6,TSPAN12,ROR1,FZD4,FZD8,LRP4,FZD1 |
| 4.998e-03 | -5.30 | transferase activity, transferring nitrogenous groups | molecular function | GO:0016769 | 23 | 7 | 17224 | 1680 |
GPT2,PHYKPL,GAPDH,ABAT,AADAT,GATM,ETNPPL |
| 5.005e-03 | -5.30 | Tryptophan catabolism | REACTOME pathways | R-HSA-71240 | 13 | 5 | 10287 | 971 |
SLC3A2,AADAT,TDO2,KMO,SLC7A5 |
| 5.041e-03 | -5.29 | F5_F8_type_C | pfam domains | PF00754 | 23 | 7 | 17054 | 1666 |
CPXM2,BTBD9,NRP1,DDR1,CNTNAP3,DCBLD1,DCBLD2 |
| 5.062e-03 | -5.29 | substrate-specific channel activity | molecular function | GO:0022838 | 441 | 60 | 17224 | 1680 |
KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,SLC9C1,LRRC8B,KCNH5,CACNA1E,JPH1,GRID1,RYR2,CHRNA6,TTYH2,RASA3,KCND3,GJC1,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B |
| 5.078e-03 | -5.28 | Gluconeogenesis, oxaloacetate => fructose-6P | KEGG pathways | M00003 | 17 | 6 | 7161 | 730 |
GAPDH,PCK2,ENO2,ENO1,ALDOC,ALDOA |
| 5.078e-03 | -5.28 | Gluconeogenesis, oxaloacetate => fructose-6P | KEGG pathways | hsa_M00003 | 17 | 6 | 7161 | 730 |
GAPDH,PCK2,ENO2,ENO1,ALDOC,ALDOA |
| 5.088e-03 | -5.28 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | 156 | 26 | 17377 | 1707 |
TNIK,VNN2,MYCBP2,PDK1,KLHL3,CCDC110,TCEA3,SELL,CBS,FAM117B,ABCC2,FAM13A,PHGDH,CD7,IKZF2,PGAP1,MTUS1,ATXN7L1,ABLIM1,GPR155,PTPRS,ZBTB20,IPCEF1,APBA2,RNF122,MLLT3 |
| 5.088e-03 | -5.28 | GSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_TH1_CD4_TCELL_D150_LCMV_UP | 156 | 26 | 17377 | 1707 |
VEGFC,LONRF1,PCDH18,RASAL2,ELOVL3,TNFSF13B,RHPN2,PRKCQ,ATF3,WDFY4,LCP2,C4orf19,DDX60L,WARS,ISG20,CXCL10,POPDC3,MAP2,GBP1,PDE10A,SCRN1,LOXL4,HK1,CMPK2,KLHL29,CEBPD |
| 5.092e-03 | -5.28 | dephosphorylation | biological process | GO:0016311 | 283 | 41 | 17256 | 1658 |
INPPL1,DUSP8,PTPRD,UBASH3B,PTPN21,LPIN3,INPP1,EYA4,PPP2R3A,PLPP1,PPM1E,CDC14B,PALD1,PPP2R2B,FIG4,PTPRE,DUSP1,PFKFB4,PPP1R3D,SSH3,PFKFB2,PTPRU,PTPN13,PTPN6,DNAJC6,PLPP2,DUSP9,PXYLP1,CTTNBP2NL,LHPP,NT5DC2,PTPRC,PTPRJ,PLPPR2,INPP4B,DUSP19,PTPRN2,PTPRS,INPP5F,BTRC,PSPH |
| 5.092e-03 | -5.28 | negative regulation of kinase activity | biological process | GO:0033673 | 283 | 41 | 17256 | 1658 |
PRKN,LATS2,DUSP8,UBASH3B,DNAJC3,IPO5,NPM1,CEBPA,PKN1,PPM1E,IGF1R,ZFYVE28,FLRT3,PRKCD,LRP6,DAB2IP,ERRFI1,SPRY2,HMGCR,DUSP1,MSTN,PTPN6,DEPTOR,PREX1,DUSP9,PRKAR2B,RACK1,WARS,CAMK2N1,IRS2,PTPRC,TRIB3,PTPRJ,WWTR1,DUSP19,BMP4,SPRY4,TESC,SMYD3,PKIA,SFN |
| 5.092e-03 | -5.28 | divalent metal ion transport | biological process | GO:0070838 | 283 | 41 | 17256 | 1658 |
CACNG3,MCOLN3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,SLC30A4,CACNB2,BHLHA15,TRPC1,CNNM2,TMEM37,NIPAL2,FAM155B,FAM155A,ATP2B1,TRPM4,SLC40A1,GPM6A,SLC3A2,CSN2,SLC39A8,ANK2,CACNA1E,JPH1,CALCRL,RASA3,RYR2,SLC39A14,PTPRC,CACHD1,ASIC1,GRIN2D,TRPC3,CACNA2D1,ATP2B4,DDIT3,TPT1,DENND5B |
| 5.097e-03 | -5.28 | negative regulation of cellular component organization | biological process | GO:0051129 | 645 | 82 | 17256 | 1658 |
EPHA3,PRKN,DNM3,ID1,FGF13,TMSB15A,LDLR,LILRB1,HDGFL3,ADD2,NPM1,TBC1D30,PPP1R9A,SKI,SCIN,TUBB4A,DACT1,MET,PACSIN1,ZNF365,SLIT2,HSPA2,PHLDB2,EVL,TMEM67,DCC,NOP53,LRRK2,FEZ1,VIM,SNCA,TRIM9,GSN,CXCL10,INSIG1,PLK2,GBP1,ARHGAP28,PTPRS,HGF,SEMA3C,INPP5F,TMOD2,ATG5,NRP1,TMEFF2,SPART,PPARGC1A,MID1,EFNB2,NECAB2,ROBO2,LGALS3,CKAP2,EPS8,LRP4,CHADL,SLX1B,USP30,PFN2,RPL13A,FHOD3,SEMA4F,PRKCD,KIAA0319,PRELID1,ADCY6,BNIP3,STXBP1,SMAD6,GFI1,SPRY2,RAPGEF2,PACSIN3,RACK1,DKK1,PLEKHH2,MYADM,PMEPA1,BMP4,SEMA3A,TBC1D4 |
| 5.110e-03 | -5.28 | YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma) | protein interactions | 7532 | 410 | 58 | 17029 | 1718 |
CGN,LATS2,MYCBP2,FN1,RASAL2,TBC1D1,CKAP2,PLEKHA5,APBB1,PKP2,KIF5C,PRKCA,TXNDC5,RAB11FIP5,TUBB4A,RASSF8,EPB41L3,BAG3,NUMBL,ABLIM1,IGF1R,RALGPS2,PPFIBP1,PRKCD,REEP1,KIAA0408,TESPA1,PAK1,DISC1,PHLDB2,SYNPO2,LCA5,GAPDH,PFKFB2,PARD3B,LRRK2,SPATA13,YAP1,WWC1,VIM,PRKCQ,BAIAP2,IRS2,KCNK15,DOCK7,RIPOR2,PRKCB,WWTR1,SH3BP4,RAI14,SVIL,TBC1D4,MAP3K20,KIF1B,SFN,LARP1,BTRC,FRMD5 |
| 5.114e-03 | -5.28 | FA58C | interpro domains | IPR000421 | 23 | 7 | 18492 | 1811 |
CPXM2,BTBD9,NRP1,DDR1,CNTNAP3,DCBLD1,DCBLD2 |
| 5.116e-03 | -5.28 | CEACAM21 (carcinoembryonic antigen related cell adhesion molecule 21) | protein interactions | 90273 | 46 | 11 | 17029 | 1718 |
EPHA3,PODXL2,FAT4,PTK7,NCR3LG1,CD276,PTPRS,MOXD1,MET,FGFR1,CNTN1 |
| 5.133e-03 | -5.27 | Golgi membrane | cellular component | GO:0000139 | 729 | 90 | 18223 | 1724 |
ATP8A1,LPCAT2,GALNT12,GALNT6,XYLT1,MYO1B,RNF24,FAM198B,MGAT5B,CHST10,SLC9A7,TLR3,SEC16B,RAB26,TMED9,PROS1,COG3,CLVS2,GALNT18,RASGRP1,ATL1,GCNT2,CD55,ERGIC1,B3GALT1,TGFA,WLS,RNF125,PXYLP1,ARHGAP21,GBP1,ATP7B,B3GALT2,TNFRSF1A,DSEL,HS3ST3B1,RAB30,HACE1,UST,SEC24D,HID1,ST6GAL1,DHCR24,CLSTN2,GALNT13,CHSY1,NDFIP2,RAB11FIP5,GBGT1,GALNT1,MGAT1,ABCA5,FUT9,HS3ST5,SREBF1,LMAN2,FIG4,ST8SIA1,NCAM1,NOS3,B4GALT6,CHSY3,IL17RD,QSOX1,PLEKHA8,RAB6B,CYTH3,MGAT4B,SYBU,LITAF,GPSM1,GALNT17,ST6GALNAC3,ARHGAP32,FNDC3A,B4GALNT3,GALNT14,GLCE,GALNT3,ICA1,SH3GL2,PMEPA1,RND3,ACER2,QPCTL,RAB31,PLD1,CERS1,B4GALT7,ABCG1 |
| 5.140e-03 | -5.27 | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_DN | MSigDB lists | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_DN | 133 | 23 | 17377 | 1707 |
PDLIM7,LCA5,DUSP8,GALNT12,EXOC6B,PRKCQ,GRK6,DOCK2,SMPDL3B,GABARAPL1,DYRK1B,FCHO2,FAM168A,MATN2,TMEM86A,SLC2A12,TSPAN13,INPP5F,EPHB6,RNF148,VGLL4,MED12L,GAB2 |
| 5.142e-03 | -5.27 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_DN | 103 | 19 | 17377 | 1707 |
BCL7A,PPP4R4,ID1,RASAL2,KDM5B,STAT4,ASAP3,GATA3,TPD52L1,RIMKLB,FBXO32,GPRC5B,FBN1,PLOD2,LAMB1,JAM2,HSPA2,ATP2B4,PCSK6 |
| 5.156e-03 | -5.27 | V$FREAC2_01 | MSigDB lists | V$FREAC2_01 | 236 | 36 | 17377 | 1707 |
BCL11B,PCDH18,SCAMP1,CHCHD7,PLAG1,RASD1,DOCK3,FOXG1,IKZF2,MECOM,FOXP2,ZNF362,KCTD15,FRY,ZNF521,FAM133A,NAP1L3,MARCKS,PPP2R2B,POU3F3,DUSP1,PAK1,BDNF,DSTN,FGF12,SLITRK5,PRDM1,ROR1,SKAP1,C4orf19,MBNL2,BCL11A,KLF12,PELI2,MCC,MID1 |
| 5.173e-03 | -5.26 | GO_LIMB_DEVELOPMENT | MSigDB lists | GO_LIMB_DEVELOPMENT | 164 | 27 | 17377 | 1707 |
INTU,B9D1,RAX,MSX1,RUNX2,BMPR2,RECK,ITGA6,LRP4,PLXNA2,ASPH,SP8,FGFR1,DKK1,SKI,DLX6,FRAS1,WDR19,PAM,TFAP2A,SEMA3C,HOXD13,DYNC2H1,BMP4,BMPR1A,SHOX2,PCSK5 |
| 5.173e-03 | -5.26 | GSE25087_FETAL_VS_ADULT_TCONV_DN | MSigDB lists | GSE25087_FETAL_VS_ADULT_TCONV_DN | 164 | 27 | 17377 | 1707 |
MAN2B2,MID2,DUSP8,TCP11L2,TNFAIP8L2,LITAF,NDRG2,CBY1,CD40,PFN2,ZFYVE9,ADAMTS17,IRS2,KLF12,HPSE,PAIP2B,IGIP,CDC14B,MAP9,EBF4,ZDHHC23,TUFT1,FAM133A,ACVR2A,KIF21A,KLF9,NR3C2 |
| 5.173e-03 | -5.26 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_UP | 164 | 27 | 17377 | 1707 |
DMXL2,SCAMP1,CFH,IL15,MPP1,BLVRB,TTYH2,CALCRL,PSD3,SPATS2L,CDC42BPA,SLC1A3,LCP2,EYA4,MTUS1,GBGT1,IGF1R,RALGPS2,PELI2,HPGD,LRP6,TMEM37,POU2F2,ETV1,LIFR,RAPGEF5,RASGRP1 |
| 5.173e-03 | -5.26 | GO_APPENDAGE_DEVELOPMENT | MSigDB lists | GO_APPENDAGE_DEVELOPMENT | 164 | 27 | 17377 | 1707 |
B9D1,INTU,RAX,MSX1,RUNX2,BMPR2,RECK,ITGA6,LRP4,PLXNA2,ASPH,SP8,FGFR1,DKK1,SKI,DLX6,FRAS1,WDR19,TFAP2A,PAM,SEMA3C,HOXD13,DYNC2H1,BMPR1A,BMP4,SHOX2,PCSK5 |
| 5.173e-03 | -5.26 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP | 164 | 27 | 17377 | 1707 |
BCL11B,MOCOS,ARAP2,EHHADH,CELSR1,RAB6B,VAMP8,PRSS35,PRKCQ,COTL1,LCP2,ABHD4,CD53,ISG20,NSD1,GYPC,PLXDC2,RASD2,B3GALT2,POU2F2,SLC1A5,CMPK2,FBXO27,GFI1,RNF122,RASGRP1,SMPDL3A |
| 5.176e-03 | -5.26 | TJP3 (tight junction protein 3) | protein interactions | 27134 | 8 | 4 | 17029 | 1718 |
TJP1,OCLN,PATJ,GJC1 |
| 5.185e-03 | -5.26 | CD1E (CD1e molecule) | protein interactions | 913 | 28 | 8 | 17029 | 1718 |
TMEM67,SEMA4F,BACE2,ENTPD7,PLXNA2,CANX,FNDC3A,NCEH1 |
| 5.195e-03 | -5.26 | MODULE_212 | MSigDB lists | MODULE_212 | 319 | 46 | 17377 | 1707 |
SV2B,MXI1,ACSL1,EHHADH,CYP2J2,ST6GAL1,UGDH,BLVRB,CBS,SCD,NEDD4,CYP26A1,MTUS1,CA2,MSMO1,BCHE,MAP7,BNIP3,PCK2,ARL4D,AGL,GATM,SNAI2,FES,TRDMT1,VAV3,GSTM2,PNP,PNRC1,GSTM4,MPP1,ACO1,STRADB,C1R,TNS1,F12,HERPUD1,ISG20,ENPP1,INSIG1,TDO2,RND3,FMO4,MAP2K6,ALDOA,HPGD |
| 5.199e-03 | -5.26 | GO_SYNAPTIC_VESICLE_RECYCLING | MSigDB lists | GO_SYNAPTIC_VESICLE_RECYCLING | 23 | 7 | 17377 | 1707 |
PACSIN1,SH3GL2,CANX,SYT12,STON2,SNCA,OPHN1 |
| 5.199e-03 | -5.26 | LI_CISPLATIN_RESISTANCE_UP | MSigDB lists | LI_CISPLATIN_RESISTANCE_UP | 23 | 7 | 17377 | 1707 |
EPHA3,UACA,ZBTB20,IGF1R,CDH2,VWDE,CYP1B1 |
| 5.199e-03 | -5.26 | GO_REGULATION_OF_CAMP_MEDIATED_SIGNALING | MSigDB lists | GO_REGULATION_OF_CAMP_MEDIATED_SIGNALING | 23 | 7 | 17377 | 1707 |
PEX5L,CXCL10,PDE10A,RAPGEF2,RASD2,GNAI1,ADRB1 |
| 5.199e-03 | -5.26 | GO_PROTEIN_TARGETING_TO_PLASMA_MEMBRANE | MSigDB lists | GO_PROTEIN_TARGETING_TO_PLASMA_MEMBRANE | 23 | 7 | 17377 | 1707 |
PRKG2,GAS6,MYADM,TESC,ANK2,EHD3,KCNB2 |
| 5.199e-03 | -5.26 | GROSS_HIF1A_TARGETS_DN | MSigDB lists | GROSS_HIF1A_TARGETS_DN | 23 | 7 | 17377 | 1707 |
BNIP3,GAPDH,PDK1,LGALS3,KCNAB1,ENO1,FAM162A |
| 5.199e-03 | -5.26 | MODULE_130 | MSigDB lists | MODULE_130 | 23 | 7 | 17377 | 1707 |
CR2,C1R,CD55,CFH,CFHR1,C4A,C4BPB |
| 5.199e-03 | -5.26 | HASLINGER_B_CLL_WITH_13Q14_DELETION | MSigDB lists | HASLINGER_B_CLL_WITH_13Q14_DELETION | 23 | 7 | 17377 | 1707 |
TUBB4A,BCL7A,DUSP8,TRIM16,RBMS2,LDLR,PNMA2 |
| 5.199e-03 | -5.26 | WAGNER_APO2_SENSITIVITY | MSigDB lists | WAGNER_APO2_SENSITIVITY | 23 | 7 | 17377 | 1707 |
GALNT3,GALNT13,GALNT1,FUT9,GALNT14,GALNT12,GALNT6 |
| 5.204e-03 | -5.26 | transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0007178 | 200 | 31 | 17256 | 1658 |
CGN,MSX1,GCNT2,PXN,ID1,RUNX2,ACVR1,SMAD9,BMPR2,MSTN,ACVR1C,LRP4,FERMT2,RYR2,VIM,ACVR2B,BMP6,ZFYVE9,SKI,SMAD3,INHBC,TGFBR3,APELA,INHBE,CHRDL1,ACVR2A,HPGD,BMPR1A,BMP4,MAGI2,SMAD6 |
| 5.209e-03 | -5.26 | GO_I_BAND | MSigDB lists | GO_I_BAND | 118 | 21 | 17377 | 1707 |
PAK1,SCN5A,SYNPO2,ANK2,SCN8A,JPH1,FHL2,RYR2,FERMT2,OBSCN,PALLD,FHOD3,NOS1AP,BAG3,FBXO32,KCNN2,PDLIM3,ALDOA,AHNAK2,NEB,ATP2B4 |
| 5.220e-03 | -5.26 | PTB/PI_dom | interpro domains | IPR006020 | 41 | 10 | 18492 | 1811 |
NUMBL,TBC1D1,EPS8,APBB1,TNS1,GULP1,APBA1,APBA2,TBC1D4,NOS1AP |
| 5.235e-03 | -5.25 | GO_ACTIN_BASED_CELL_PROJECTION | MSigDB lists | GO_ACTIN_BASED_CELL_PROJECTION | 172 | 28 | 17377 | 1707 |
GPM6A,INPPL1,FARP1,FGF13,AKAP5,MYO10,MPP1,EPS8,APBB1,HOMER2,MYO1B,LRRK2,SPATA13,ENAH,EPHB1,PPP1R9A,NEDD4,TIAM2,BAIAP2,PLS3,CA2,FAT1,ITGB3,ACTA2,ADCY6,OXTR,MYO6,FOXA1 |
| 5.235e-03 | -5.25 | GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_DN | MSigDB lists | GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_DN | 172 | 28 | 17377 | 1707 |
RPS20,VEGFC,CDH26,THOC5,LGALS3,COL4A4,PLAG1,SYBU,JPH1,GALNT13,TTC28,GPR137C,TMEM74,FKBP11,MTUS1,EFEMP1,RANBP2,NSD1,FBXO32,PLAGL1,MSMO1,MAP7,SCRN1,SQLE,NIPAL2,FIGN,LRP12,CHMP4C |
| 5.242e-03 | -5.25 | regulation of ventricular cardiac muscle cell action potential | biological process | GO:0098911 | 18 | 6 | 17256 | 1658 |
TRPM4,RYR2,PKP2,DSP,DSG2,NOS1AP |
| 5.242e-03 | -5.25 | positive regulation of mast cell activation | biological process | GO:0033005 | 18 | 6 | 17256 | 1658 |
FGR,GATA2,STXBP1,SYK,VAMP8,GAB2 |
| 5.242e-03 | -5.25 | cell communication by electrical coupling | biological process | GO:0010644 | 18 | 6 | 17256 | 1658 |
RYR2,DBN1,PKP2,ATP1B1,ATP1A3,GJC1 |
| 5.242e-03 | -5.25 | paraxial mesoderm development | biological process | GO:0048339 | 18 | 6 | 17256 | 1658 |
SMAD3,YAP1,EPB41L5,WNT11,BMPR1A,FGFR1 |
| 5.252e-03 | -5.25 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | KEGG pathways | ko05412 | 72 | 15 | 7161 | 730 |
TCF7L1,ITGB7,CACNG3,CACNB2,ITGA6,DSG2,ITGA2,ITGB3,RYR2,PKP2,CDH2,DSP,CACNB4,CACNA2D1,CTNNA2 |
| 5.252e-03 | -5.25 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | KEGG pathways | hsa05412 | 72 | 15 | 7161 | 730 |
TCF7L1,ITGB7,CACNG3,CACNB2,ITGA6,DSG2,ITGA2,ITGB3,RYR2,PKP2,CDH2,DSP,CACNB4,CACNA2D1,CTNNA2 |
| 5.252e-03 | -5.25 | Adherens junction | KEGG pathways | ko04520 | 72 | 15 | 7161 | 730 |
SMAD3,FER,TCF7L1,WASF3,PTPRJ,SORBS1,IGF1R,PTPN6,TJP1,MET,RAC3,SNAI2,FGFR1,BAIAP2,CTNNA2 |
| 5.252e-03 | -5.25 | Adherens junction | KEGG pathways | hsa04520 | 72 | 15 | 7161 | 730 |
SMAD3,FER,TCF7L1,WASF3,PTPRJ,SORBS1,IGF1R,PTPN6,TJP1,MET,RAC3,SNAI2,FGFR1,BAIAP2,CTNNA2 |
| 5.278e-03 | -5.24 | GSE13229_MATURE_VS_INTMATURE_NKCELL_UP | MSigDB lists | GSE13229_MATURE_VS_INTMATURE_NKCELL_UP | 180 | 29 | 17377 | 1707 |
DLGAP1,BTC,LGALS3,STAT4,MGAT4B,ATP6V1E2,TMEM200C,HERC6,KHDRBS2,RADIL,SLCO3A1,STEAP1,PPP2R3A,RERE,CEBPB,GPR15,FGR,TLR3,IGF1R,CPVL,TACC2,MFSD2A,MCF2L,BEND4,PACSIN1,MOXD1,SHOX2,ATP1A3,SNX7 |
| 5.278e-03 | -5.24 | GO_REGULATION_OF_EXOCYTOSIS | MSigDB lists | GO_REGULATION_OF_EXOCYTOSIS | 180 | 29 | 17377 | 1707 |
EXPH5,DOC2A,FER,RAB3B,STXBP5L,SYT12,STXBP6,RAPGEF4,VAMP8,LRRK2,SYT14,PLCB1,PFN2,PCLO,NCS1,SNCA,TRIM9,FGR,UNC13B,RAB26,CADPS2,SEPT5,RAB27B,STXBP1,SYK,TC2N,RIMS2,FES,GAB2 |
| 5.302e-03 | -5.24 | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | 188 | 30 | 17377 | 1707 |
PPP1R3D,MYCBP2,ZNF516,SH3BP2,ERGIC1,GPR65,ASS1,MRPL22,SORBS3,MARS,CADM2,GAS6,NHP2,OR11H4,INPP1,PCLO,COL27A1,WARS,TMEM53,CXCL10,RSL24D1,SETDB2,PMEPA1,MYC,SLC7A5,FAM84B,GEM,NCEH1,SPOCK3,LRP12 |
| 5.302e-03 | -5.24 | GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP | MSigDB lists | GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP | 188 | 30 | 17377 | 1707 |
CXCR5,RWDD2A,EBPL,ST14,RECK,JDP2,GJB2,CYP4V2,NRN1,CEBPA,GSTO1,ARRDC4,ABHD4,GRPEL2,GABARAPL1,HOPX,EPCAM,CNKSR3,ALDOC,ACER2,CSF1,CLDN12,MATN2,PRELID2,HK2,P4HA1,SH3BGRL2,RAPGEF5,CSRP2,RRAGD |
| 5.302e-03 | -5.24 | GSE2826_WT_VS_BTK_KO_BCELL_DN | MSigDB lists | GSE2826_WT_VS_BTK_KO_BCELL_DN | 188 | 30 | 17377 | 1707 |
TYRO3,VNN2,BDNF,ENAM,GNG12,ACSL1,WLS,DHCR24,FHDC1,GATA3,ATP1B1,PRKCA,COL14A1,PHLDA2,ZIC1,AHRR,GALNT3,ENPP1,NAV1,P4HA2,MATN2,TNFRSF1A,PAM,SLCO5A1,P4HA1,COL19A1,MAPK13,PAX9,GATM,CTNND2 |
| 5.305e-03 | -5.24 | GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_UP | 141 | 24 | 17377 | 1707 |
MID2,BDNF,PLSCR4,PRSS12,RBFOX2,PTPN13,TNFSF13B,TTYH2,CANX,TEX9,IL18R1,EPDR1,SCIN,DCBLD2,TRIM9,CXCL10,NAV1,UNC13B,PLOD2,PPFIBP1,PTPRS,SPRY4,SPRED3,OSBPL6 |
| 5.305e-03 | -5.24 | GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN | MSigDB lists | GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN | 141 | 24 | 17377 | 1707 |
LATS2,CARD6,KCNIP3,PNRC1,CLGN,WLS,FAM84A,FOXN3,KIF5C,CD7,RERE,DEXI,EPCAM,DOCK7,FBXO32,EOMES,SLC22A17,PLK2,AKT3,EIF1,BDH2,PGM2L1,SERPINI1,GEM |
| 5.306e-03 | -5.24 | glutathione transferase activity | molecular function | GO:0004364 | 35 | 9 | 17224 | 1680 |
GDAP1,GSTM2,ALOX5AP,GSTO2,MGST3,GSTM4,GSTM3,GSTO1,PTGES |
| 5.309e-03 | -5.24 | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | 196 | 31 | 17377 | 1707 |
DBN1,MYCBP2,GARS,TTC39B,CFH,FGF13,IL15,THSD4,PTPN13,TES,PLEKHA5,GPR65,ARHGAP22,LRMP,DEPTOR,PPFIBP2,GSTO1,C3orf70,MBNL2,IL18R1,RNF150,MYADM,DACT1,PRELID1,TNFRSF1A,FAM149A,SLC1A5,MET,RAB30,DUSP1,TLL2 |
| 5.309e-03 | -5.24 | CAIRO_HEPATOBLASTOMA_UP | MSigDB lists | CAIRO_HEPATOBLASTOMA_UP | 196 | 31 | 17377 | 1707 |
CREB3L2,KDM5B,RHOBTB1,CRIM1,CAP2,PLAG1,ITGA6,FASN,HIP1,IGF2BP2,SCD,PRKCA,PALLD,DKK1,CYP51A1,EPCAM,HMGCS1,ZBTB38,WFS1,RAP2A,SQLE,CLMN,TUFT1,MARCKS,TBC1D9,FNBP1L,ETV1,HSPA2,SMYD3,CKAP4,HMGCR |
| 5.327e-03 | -5.23 | phosphorylation | biological process | GO:0016310 | 1261 | 148 | 17256 | 1658 |
MVK,ACVR1,FGF13,STAT5B,PRKCA,STK24,MOK,RPS6KA2,TGFBR3,NDUFB8,EPHB6,TLR4,ENO1,PRKACB,RASGRP1,PDGFRB,TNK2,MARK1,SMAD9,ACVR1C,LRRK2,ACVR2B,ROR1,FGF17,SGK2,GRK3,DYRK1B,AK1,RASGRF2,PLK2,ERN1,ALDOA,MAPK13,PIK3C2B,OXTR,MEF2C,PRKAA2,TYRO3,LATS2,SLK,TNFRSF19,DOK5,EFEMP1,IGF1R,ADCK1,PIK3AP1,MYC,PRKG1,ALPK1,NCAM1,MAST4,GFRA1,PAK1,FGFR4,IL17RD,DUSP9,OBSCN,STRADB,CDC42BPA,MAPKAPK2,PKN3,PELI2,HK2,PANK3,EPHA3,BTC,NEK10,RASAL2,IL15,MAPK4,NTRK3,CHUK,GRK6,DDR1,PIBF1,SPEG,TLR3,ALDOC,RPS6KL1,MYO3B,ACVR2A,DAB2IP,MET,IGFBP3,FER,GAPDH,MYLK3,PDK1,PFKFB2,ADM2,KCNH5,PTPN6,PANK1,PRKCQ,WNT11,FRK,FGFR1,TPK1,SNCA,IRS2,PRKCB,PTK7,ABI3,MAP3K21,HGF,BMPR1A,MAPK10,MAST1,TNIK,DYRK3,ENO2,BMPR2,PAK5,GAS6,PKN1,EPHB1,INPP1,PRKCD,GHR,SGK3,SGK1,PRKG2,IQGAP3,SYK,ZFP36L2,FES,PFKFB4,HYKK,RAPGEF2,OGDHL,NUAK2,AK4,RASA3,PEAK1,TRIB3,FGR,AKT3,MAP2K6,NEK11,PGM2L1,PIP5KL1,GRIN2D,LRRK1,BMP4,HK1,CMPK2,MAP3K20,BTRC |
| 5.330e-03 | -5.23 | ZHAN_MULTIPLE_MYELOMA_LB_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_LB_UP | 41 | 10 | 17377 | 1707 |
PHACTR3,KIAA0895,BIK,ARID5B,C1orf226,PLS1,CTTN,MAST4,COL9A2,RASGRP1 |
| 5.334e-03 | -5.23 | GAGCCTG,MIR-484 | MSigDB lists | GAGCCTG,MIR-484 | 96 | 18 | 17377 | 1707 |
MYCBP2,NFIA,NFE2L1,FAM13A,ZIC1,PCDH7,DCBLD2,TRPS1,BCL11A,MAPKAPK2,PLEKHH2,NAV1,KLF12,PRKCB,ZIC5,GRB10,PTPRE,PGBD5 |
| 5.344e-03 | -5.23 | neuron projection cytoplasm | cellular component | GO:0120111 | 70 | 14 | 18223 | 1724 |
KCNAB1,MAP1A,GRIK2,MAP2,WLS,KIF5A,LRRK2,SYBU,ABHD13,DLG2,CANX,KIF1B,BAIAP2,GABARAPL1 |
| 5.352e-03 | -5.23 | EGF_1 | prosite domains | PS00022 | 175 | 30 | 12060 | 1278 |
TENM1,ITGB7,BTC,FN1,CELSR1,CELSR3,TGFA,LAMC3,SELL,F12,GAS6,BCAN,DNER,HEG1,NELL2,NRG3,FAT4,ITGBL1,FBN1,FAT1,VWDE,LAMB1,ITGB3,SCARF2,ATRNL1,EGFL7,PROS1,TMEFF2,NTNG1,SLIT2 |
| 5.355e-03 | -5.23 | phosphatidylinositol-mediated signaling | biological process | GO:0048015 | 62 | 13 | 17256 | 1658 |
TYRO3,IRS2,GSN,IGF1R,GATA3,INPP5F,PIK3C2B,PLEKHA1,CA8,FGFR1,NCS1,PDGFRB,GAB2 |
| 5.355e-03 | -5.23 | mesoderm morphogenesis | biological process | GO:0048332 | 69 | 14 | 17256 | 1658 |
SMAD3,EPB41L5,ACVR1,EOMES,BMPR2,WLS,APELA,ITGB3,ITGA2,WNT11,BMPR1A,BMP4,SIX2,DKK1 |
| 5.357e-03 | -5.23 | GO_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY | MSigDB lists | GO_POSITIVE_REGULATION_OF_SYNAPSE_ASSEMBLY | 54 | 12 | 17377 | 1707 |
BDNF,SLITRK2,LRRN1,FLRT3,CLSTN2,SLITRK5,NTRK3,AMIGO1,OXTR,NRXN1,EPHB1,CBLN1 |
| 5.357e-03 | -5.23 | HALLMARK_TGF_BETA_SIGNALING | MSigDB lists | HALLMARK_TGF_BETA_SIGNALING | 54 | 12 | 17377 | 1707 |
SMAD3,ID3,ACVR1,ID1,BMPR2,PMEPA1,WWTR1,RAB31,TJP1,BMPR1A,SMAD6,SKI |
| 5.357e-03 | -5.23 | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN | MSigDB lists | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_DN | 54 | 12 | 17377 | 1707 |
CXCR5,VNN2,ID3,PTPN6,ST6GAL1,LRMP,SCRN1,POU2F2,CD40,SEL1L3,GATM,BCL11A |
| 5.362e-03 | -5.23 | negative regulation of cell projection organization | biological process | GO:0031345 | 168 | 27 | 17256 | 1658 |
EFNB2,DNM3,EVL,ID1,FGF13,DCC,RAPGEF2,LRRK2,LRP4,VIM,PFN2,TBC1D30,SEMA4F,PLK2,PRKCD,KIAA0319,ADCY6,PTPRS,INPP5F,SEMA3C,SPART,NRP1,ZNF365,SEMA3A,GFI1,SPRY2,SLIT2 |
| 5.419e-03 | -5.22 | intracellular sterol transport | biological process | GO:0032366 | 13 | 5 | 17256 | 1658 |
LRP6,NPC2,LDLR,STARD4,ABCG1 |
| 5.419e-03 | -5.22 | negative regulation of skeletal muscle tissue development | biological process | GO:0048642 | 13 | 5 | 17256 | 1658 |
YBX3,EPHB1,MSTN,DKK1,TLL2 |
| 5.419e-03 | -5.22 | negative regulation of keratinocyte proliferation | biological process | GO:0010839 | 13 | 5 | 17256 | 1658 |
INTU,KLF9,CTSV,SNAI2,SFN |
| 5.419e-03 | -5.22 | positive regulation of B cell differentiation | biological process | GO:0045579 | 13 | 5 | 17256 | 1658 |
STAT5B,PRDM1,NCKAP1L,SYK,XBP1 |
| 5.421e-03 | -5.22 | negative regulation of cell differentiation | biological process | GO:0045596 | 683 | 86 | 17256 | 1658 |
DNM3,ID1,FGF13,LDLR,LILRB1,PKP2,GATA3,STAT5B,NTRK3,SKI,TLR3,ITGB3,BCL6,DAB2IP,ZNF365,TLR4,SLIT2,SNAI2,NKX2-1,PRAME,MEIS2,DCC,NKX3-2,LRRK2,YAP1,VIM,SMAD3,ENPP1,CXCL10,NRG3,INSIG1,PLK2,GBP1,RBPMS2,WWTR1,PTPRS,SEMA3C,INPP5F,BMPR1A,DLX2,SPART,TNFSF4,NRP1,EFNB2,UBASH3B,JDP2,LRP4,CHADL,OVOL2,EPHB1,FOXG1,HOPX,NKX6-1,EFEMP1,SEMA4F,CNTN4,GATA2,ABCA5,BHLHA15,MYC,C1QL4,KIAA0319,ADCY6,GFI1,ZFP36L2,PAK1,TRPM4,BDNF,MSX1,MSTN,RAPGEF2,PRICKLE1,MAFB,ZFPM2,DKK1,TRIB3,ID3,FBN1,TERT,XBP1,BMP4,SEMA3A,SIX2,FOXA1,DDIT3,ABCG1 |
| 5.437e-03 | -5.21 | Ca-dependent events | REACTOME pathways | R-HSA-111996 | 30 | 8 | 10287 | 971 |
PLA2G4A,PDE1B,PRKCD,ADCY1,ADCY6,PRKAR2B,PRKCA,PRKACB |
| 5.438e-03 | -5.21 | GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_DN | MSigDB lists | GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_DN | 149 | 25 | 17377 | 1707 |
RGS16,SKAP2,NR4A1,UBASH3B,LITAF,SETBP1,RNF125,GSTO1,BATF,ARRDC4,TAF4B,TBC1D19,TRPS1,ISG20,HEG1,ENTPD1,CXCL10,ARHGAP21,MFSD2A,PLXDC2,TRPC1,TOX,PACSIN1,NEB,FILIP1 |
| 5.445e-03 | -5.21 | BMPR2 (bone morphogenetic protein receptor type 2) | protein interactions | 659 | 66 | 14 | 17029 | 1718 |
TUBB4A,TRIB3,ACVR1,BMPR2,LRRIQ1,PRKCB,FHL2,NBEA,TRPC1,BMPR1A,BMP4,SMAD6,BMP6,CES3 |
| 5.446e-03 | -5.21 | PTEN_DN.V2_DN | MSigDB lists | PTEN_DN.V2_DN | 126 | 22 | 17377 | 1707 |
TRPM4,PCSK1N,MRC2,AKAP5,PLAG1,CRIP2,OGDHL,RASA3,CEBPA,NEO1,BATF3,TACC2,TERT,ENTPD7,FABP6,SGK1,BMP4,DLX2,SERPINH1,MID1,FES,NOS3 |
| 5.472e-03 | -5.21 | G_PROTEIN_RECEP_F2_3 | prosite domains | PS50227 | 27 | 8 | 12060 | 1278 |
CALCRL,ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRL2,ADGRB2,ADGRL1 |
| 5.472e-03 | -5.21 | membrane depolarization during action potential | biological process | GO:0086010 | 42 | 10 | 17256 | 1658 |
TRPM4,SCN5A,SCN1B,CACNB2,CACNA1E,SCN8A,ANK2,SCN2A,CACNA2D1,SCN3A |
| 5.472e-03 | -5.21 | pyruvate biosynthetic process | biological process | GO:0042866 | 42 | 10 | 17256 | 1658 |
GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,OGDHL,HK2,PGM2L1,HK1,ENO1 |
| 5.498e-03 | -5.20 | BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 | MSigDB lists | BONCI_TARGETS_OF_MIR15A_AND_MIR16_1 | 89 | 17 | 17377 | 1707 |
EFNB2,GPR63,RECK,PLAG1,OTX1,ARL2,SPEG,PLAGL1,KPNA3,KCNAB1,ADAMTS3,AKT3,GHR,ACVR2A,KIF21A,BMPR1A,BTRC |
| 5.498e-03 | -5.20 | GO_ACTIN_FILAMENT_BASED_MOVEMENT | MSigDB lists | GO_ACTIN_FILAMENT_BASED_MOVEMENT | 89 | 17 | 17377 | 1707 |
EPB41L5,SCN5A,ANK2,MYO1B,FGF12,PKP2,RYR2,VIM,GJC1,WIPF3,SCN1B,CACNB2,TPM1,MYO6,FNBP1L,NEB,CACNA2D1 |
| 5.498e-03 | -5.20 | GO_FILOPODIUM | MSigDB lists | GO_FILOPODIUM | 89 | 17 | 17377 | 1707 |
GPM6A,INPPL1,FARP1,FGF13,AKAP5,MYO10,APBB1,MYO1B,SPATA13,ENAH,EPHB1,PPP1R9A,BAIAP2,TIAM2,FAT1,ITGB3,ACTA2 |
| 5.505e-03 | -5.20 | GO_LIPID_BINDING | MSigDB lists | GO_LIPID_BINDING | 624 | 81 | 17377 | 1707 |
DOC2A,ARHGAP26,PLA2G4A,SYT12,PLEKHA5,MYO1B,ITPR2,SYT14,SNX9,NUP62CL,PCLO,ZFYVE9,CYP26A1,SCIN,F3,UNC13B,ZFYVE28,STARD4,FABP6,DAB2IP,MARCKS,PACSIN1,CLVS2,PLTP,TLR4,SNX10,HSPA2,RASGRP1,GAB2,FER,CD55,MARK1,PREX1,PLEKHA1,SNCA,PEMT,PIK3C2B,NR3C2,TC2N,LPAR2,ALOX5AP,STXBP6,MCTP2,OPHN1,SELL,WDFY4,GAS6,APBA1,PFN2,ARHGAP44,TECPR1,SOAT2,MCF2L,SGK3,CADPS2,SH3PXD2B,FES,SNX7,ARAP2,PLEKHA8,MYO10,RAPGEF2,ESRRG,CYTH3,PACSIN3,HIP1,FERMT2,ARHGAP32,NPC2,PLCB1,TLR6,LRAT,ID3,SH3GL2,FCHO2,OSBPL5,PLD1,FNBP1L,OSBPL6,ATP1A3,ABCG1 |
| 5.543e-03 | -5.20 | GSE4984_GALECTIN1_VS_LPS_STIM_DC_DN | MSigDB lists | GSE4984_GALECTIN1_VS_LPS_STIM_DC_DN | 157 | 26 | 17377 | 1707 |
CARS,ARAP2,TTC39B,CLGN,LRRC8B,IPO5,LRMP,HECW2,MARS,ATP11A,DOCK5,CHN1,MAPKAPK2,TEX15,B3GALT2,GTF2F2,TSC22D1,ATRNL1,TMEM117,MYOM2,GEM,VASH2,DISP2,PTPRE,STON2,LPP |
| 5.561e-03 | -5.19 | PID_ARF6_PATHWAY | MSigDB lists | PID_ARF6_PATHWAY | 35 | 9 | 17377 | 1707 |
ARAP2,PXN,CYTH3,ITGB3,HGF,IPCEF1,GULP1,MET,TSHR |
| 5.561e-03 | -5.19 | HALLMARK_HEDGEHOG_SIGNALING | MSigDB lists | HALLMARK_HEDGEHOG_SIGNALING | 35 | 9 | 17377 | 1707 |
NKX6-1,RTN1,UNC5C,CELSR1,VLDLR,OPHN1,NRP1,HEY1,GLI1 |
| 5.561e-03 | -5.19 | GO_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CATION_CHANNEL_ACTIVITY | 35 | 9 | 17377 | 1707 |
GSTM2,AKAP7,CACNB2,ANK2,GSTO1,BMP4,ASPH,CACNA2D1,NOS1AP |
| 5.561e-03 | -5.19 | GO_CORONARY_VASCULATURE_DEVELOPMENT | MSigDB lists | GO_CORONARY_VASCULATURE_DEVELOPMENT | 35 | 9 | 17377 | 1707 |
PTK7,PRICKLE1,ADAMTS6,DYNC2H1,PRDM1,NRP1,SMAD6,PDGFRB,PCSK5 |
| 5.561e-03 | -5.19 | GO_HEAD_MORPHOGENESIS | MSigDB lists | GO_HEAD_MORPHOGENESIS | 35 | 9 | 17377 | 1707 |
MSX1,ARID5B,LRP6,PLEKHA1,PAX9,ASPH,CRISPLD1,SKI,DKK1 |
| 5.561e-03 | -5.19 | SEMENZA_HIF1_TARGETS | MSigDB lists | SEMENZA_HIF1_TARGETS | 35 | 9 | 17377 | 1707 |
BNIP3,GAPDH,HK1,ENO1,ALDOC,P4HA2,ALDOA,IGFBP3,HK2 |
| 5.561e-03 | -5.19 | MARZEC_IL2_SIGNALING_DN | MSigDB lists | MARZEC_IL2_SIGNALING_DN | 35 | 9 | 17377 | 1707 |
PTPRC,CARD6,CACNG3,MAP2K6,CACNA1E,CCNG1,PLCB1,SESN1,TNFRSF11A |
| 5.568e-03 | -5.19 | GO_BROWN_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_BROWN_FAT_CELL_DIFFERENTIATION | 29 | 8 | 17377 | 1707 |
CEBPB,BNIP3,CEBPA,RARRES2,ZNF516,PPARGC1A,ITGA6,ADRB1 |
| 5.568e-03 | -5.19 | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | 29 | 8 | 17377 | 1707 |
CEBPA,FGR,ALOX5AP,PKN1,IGFBP6,HOXA1,BIK,LITAF |
| 5.568e-03 | -5.19 | SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN | MSigDB lists | SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN | 29 | 8 | 17377 | 1707 |
TNK2,EIF1,SLC7A5,ATF3,KLF9,BAIAP2,ATP2B4,PLS3 |
| 5.575e-03 | -5.19 | regulation of apoptotic signaling pathway | biological process | GO:2001233 | 388 | 53 | 17256 | 1658 |
PRKN,ACVR1,LGALS3,PAK5,ITGA6,BIK,TPD52L1,EYA4,GSDME,PMAIP1,PRKCD,MAGEA3,PRELID1,SGK3,DAB2IP,HRK,BNIP3,CTTN,YBX3,ENO1,SNAI2,ZNF385A,NOS3,CTH,RPL26,ATP5IF1,ATF4,MSX1,LRRK2,DEPTOR,YAP1,STRADB,ATF3,RACK1,FAM162A,HERPUD1,FGFR1,SMAD3,GSN,NACC2,TERT,SH3RF1,WFS1,XBP1,PCGF2,BBC3,HGF,BMP4,UNC5B,NRP1,DDIT3,SFN,TPT1 |
| 5.582e-03 | -5.19 | GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION | 61 | 13 | 17377 | 1707 |
PTPRC,IRS2,VEGFC,EPCAM,FOXP2,DISC1,TERT,MYC,SMARCD3,BMP4,BMPR1A,SHOX2,FGFR1 |
| 5.583e-03 | -5.19 | - | gene3d domains | 4.10.1240.10 | 27 | 8 | 8148 | 867 |
CALCRL,ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRL2,ADGRB2,ADGRL1 |
| 5.590e-03 | -5.19 | negative regulation of protein complex assembly | biological process | GO:0031333 | 129 | 22 | 17256 | 1658 |
TMSB15A,NOP53,EPS8,ADD2,PFN2,RPL13A,FHOD3,SNCA,DKK1,SCIN,TRIM9,TUBB4A,GSN,MYADM,INSIG1,PMEPA1,DACT1,PRKCD,TMOD2,STXBP1,SMAD6,SLIT2 |
| 5.593e-03 | -5.19 | cellular macromolecule localization | biological process | GO:0070727 | 1396 | 162 | 17256 | 1658 |
EXPH5,THOC5,CACNG3,UGT8,FGF13,GRIK2,NPM1,SNX9,NUP62CL,TRPS1,ADPRHL1,SEC16B,PMAIP1,RAP2A,RAB26,NDUFB8,TBC1D32,LIN7A,TMED9,CTTN,COG3,TLN2,PACSIN1,MYRIP,CPE,TBC1D8,DBN1,GDAP1,ITGB7,KCNIP3,WLS,ANK2,LRRK2,ZDHHC14,GSN,INSIG1,TNFRSF1A,NRP1,MAGI2,RRAGD,CELSR1,HID1,SEC24D,TBC1D1,STXBP6,APBA1,BBS9,RPL13A,GRPEL2,CACNB2,RPS11,LRP6,STXBP1,RPS23,ZNF385A,RIMS2,BOD1,RPL26,MID2,TBC1D8B,DCHS1,RYR2,OBSCN,STRADB,HIP1,PEX5L,SNAP25,HERPUD1,SPATA7,TBC1D2,RPL28,FCHO2,WDR19,SH3BP4,RAB31,HK2,CDH2,TESC,SIX2,PRKN,ID1,AKAP5,TMSB15A,RHOD,PKP2,NRXN1,PIBF1,TBC1D30,ZFYVE9,SCIN,EPB41L3,ZDHHC6,REEP1,ZDHHC23,BCL6,MAP7,RTKN2,RAB27B,SNX10,KCNB2,RPS13,DPP10,NOP53,PTPRU,WNT11,RAB38,SYNJ2BP,PYGO1,ATP1B1,TBC1D16,RANBP2,KPNA3,GBP1,SEPT5,MID1,RAB30,THOC3,RPS20,TNIK,TSPAN15,LRP4,IPO5,UBAC2,ARL2,KIF5C,GAS6,P2RY1,TSPAN17,ARHGAP44,NEDD4,RPL34,MAP1A,EHD3,PRKG2,SH3PXD2B,DYNC2H1,TBC1D9,MYO6,SEPT3,RAB3B,MSX1,RAB6B,RAPGEF2,RPL21,ZDHHC15,FERMT2,PRICKLE1,SKAP1,RERE,HOMER3,RPL12,MYADM,TERT,NACC2,DLG2,RPL4,HK1,BMP4,RPS12,TBC1D4,KIF1B,DDIT3 |
| 5.594e-03 | -5.19 | SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2) | protein interactions | 23380 | 94 | 18 | 17029 | 1718 |
CGN,DISC1,PHLDB2,RASAL2,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,SH3BP4,TANC2,KIF1B,OSBPL6,LARP1,GAB2 |
| 5.595e-03 | -5.19 | CLEC2D (C-type lectin domain family 2 member D) | protein interactions | 29121 | 73 | 15 | 17029 | 1718 |
PTPRU,CNTNAP3,BACE2,SLC22A18,ATP7B,ADGRL1,DYNC2LI1,ST6GALNAC3,GAS6,CANX,FNDC3A,TMEM120B,SLC19A2,FRMD5,ARFGEF3 |
| 5.621e-03 | -5.18 | skin-knee-malignant_melanoma | COSMIC cancer mutations | skin-knee-malignant_melanoma | 97 | 18 | 17385 | 1698 |
FER,PTPRD,DCC,PTPN13,PTPN21,TNS1,EPHB1,KHDRBS2,PTPRC,TMEM132B,PTPRJ,ADAMTS3,PTK7,PTPRS,PTPRN2,MET,PTPRE,CHRM3 |
| 5.621e-03 | -5.18 | GO_HEART_PROCESS | MSigDB lists | GO_HEART_PROCESS | 82 | 16 | 17377 | 1707 |
SCN5A,ANK2,FGF12,PKP2,RYR2,ATP1B1,GJC1,RPS6KA2,SCN1B,MAP2K6,CACNB2,PDE4D,TPM1,ATG5,CACNA2D1,ATP1A3 |
| 5.621e-03 | -5.18 | GO_CARDIAC_SEPTUM_DEVELOPMENT | MSigDB lists | GO_CARDIAC_SEPTUM_DEVELOPMENT | 82 | 16 | 17377 | 1707 |
ACVR1,ANK2,GATA3,ADAMTS6,WNT11,PRDM1,ZFPM2,SAV1,HEG1,HEYL,PTK7,BMP4,SMAD6,PCSK5,HEY1,FZD1 |
| 5.621e-03 | -5.18 | GO_REGULATION_OF_CATION_CHANNEL_ACTIVITY | MSigDB lists | GO_REGULATION_OF_CATION_CHANNEL_ACTIVITY | 82 | 16 | 17377 | 1707 |
GSTM2,KCNAB1,AKAP7,CACNB2,ANK2,KCNG1,JPH1,FGF12,GSTO1,BMP4,PDE4D,CACNB4,ASPH,CACNA2D1,NOS1AP,STOM |
| 5.621e-03 | -5.18 | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_UP | 165 | 27 | 17377 | 1707 |
QSOX1,PPP1R3D,SEMA6B,OPLAH,ID1,PDK1,EPS8,DHCR24,MAFB,CHSY1,GAS6,DDIT4,SMAD3,SLC39A14,ENPP1,CPNE2,SIPA1L2,PMEPA1,ALDOC,EMILIN2,HK2,ZDHHC23,ATRNL1,P4HA1,PDE4D,VGLL4,CRYL1 |
| 5.634e-03 | -5.18 | regulation of cellular localization | biological process | GO:0060341 | 785 | 97 | 17256 | 1658 |
EPHA3,PRKN,DNM3,SORBS1,AKAP5,SYT12,VAMP8,NRXN1,PPP1R9A,BAG3,UNC13B,SEC16B,TCAF2,PMAIP1,KMO,REEP1,TRPC1,PDE4D,GAB2,DPP10,FER,SESN2,PTPN6,ANK2,JPH1,LRRK2,BNIP3L,FEZ1,GSTO1,SNCA,GNAI1,SMAD3,GSN,CXCL10,KCNMB4,INSIG1,MAP2,GBP1,ASIC1,BBC3,INPP5F,ATG5,SEPT5,MAGI2,MEF2C,PRKAA2,TENM1,NECAB2,BVES,FBXO4,UBASH3B,LRP4,IPO5,UBAC2,BTBD9,GAS6,GPSM2,KCNC4,MLC1,PFN2,GAS1,NEDD4,RAB11FIP5,MAP1A,GATA2,PRKCD,SREBF1,STXBP1,SYK,FES,RIMS2,PARP9,HMGCR,PAK1,TRPM4,ATP5IF1,BDNF,GSTM2,RAB3B,RHOQ,SYBU,RYR2,WWC1,PLS1,RACK1,ZIC1,MAP1B,GPLD1,FGR,RIPOR2,TERT,BMP4,TRPC3,CDH2,PKIA,SFN,STOM |
| 5.634e-03 | -5.18 | CACTTTG,MIR-520G,MIR-520H | MSigDB lists | CACTTTG,MIR-520G,MIR-520H | 221 | 34 | 17377 | 1707 |
TBKBP1,SLC6A9,RUNX2,CELSR3,YPEL2,CHUK,TNKS1BP1,PFN2,TRPS1,SKI,CCNJ,ZNF362,FLRT3,NBEA,PRICKLE2,TBC1D9,SMAD6,DBN1,DPYSL5,ARAP2,RNF145,PTPN13,VLDLR,SATB2,FNDC3A,PLCB1,SLC39A14,CAMK2N1,KLF12,KPNA3,PLOD2,SPRY4,NEUROG2,MAGI2 |
| 5.634e-03 | -5.18 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | 221 | 34 | 17377 | 1707 |
MOCOS,FARP1,BLVRB,TPD52L1,SLC19A2,NOS1AP,CHRNA5,CNKSR3,MYC,STC2,SGK3,OPN3,SGK1,TMEM120B,GAB2,MICAL2,SLC27A2,SYBU,DEPTOR,MARS,ATP11A,FRK,ISG20,SLC7A1,PLOD2,RAB31,SLC7A5,SVIL,KIF21A,PAX9,TPM1,SLC1A5,SEPT5,PTGES |
| 5.640e-03 | -5.18 | human chrXq21.32 | chromosome location | human chrXq21.32 | 2 | 2 | 26185 | 1967 |
FAM133A,NAP1L3 |
| 5.643e-03 | -5.18 | REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL | MSigDB lists | REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL | 134 | 23 | 17377 | 1707 |
GNG12,CACNG3,AKAP5,GRIK2,GABRB2,ADCY1,GABRG2,CHRNA6,GABRR2,PRKCA,PLCB1,GNAI1,GRIK4,KCNJ4,RPS6KA2,CHRNA5,PRKCB,RASGRF2,GNB4,ADCY6,GRIN2D,MYO6,PRKACB |
| 5.643e-03 | -5.18 | MODULE_119 | MSigDB lists | MODULE_119 | 134 | 23 | 17377 | 1707 |
FADS1,MYCBP2,ITGB7,ARAP2,IL15,STAT4,LRMP,SELL,LILRB1,CR2,PRKCQ,USP30,ISG20,PTPRC,CPVL,KLF12,NEK11,PIK3C2B,DBP,POU2F2,PTPRCAP,MED12L,RRAGD |
| 5.647e-03 | -5.18 | proline-rich region binding | molecular function | GO:0070064 | 18 | 6 | 17224 | 1680 |
YAP1,GAREM1,APBB1,NEDD4,BAIAP2,GHR |
| 5.647e-03 | -5.18 | nucleotide diphosphatase activity | molecular function | GO:0004551 | 18 | 6 | 17224 | 1680 |
ENPP1,NUDT10,GARS,FHIT,NUDT12,NUDT17 |
| 5.654e-03 | -5.18 | ITPR1 (inositol 1,4,5-trisphosphate receptor type 1) | protein interactions | 3708 | 53 | 12 | 17029 | 1718 |
RNF170,ITPRIP,PLK2,PRKCD,HOMER2,PRKG1,RYR2,TRPC1,CA8,TRPC3,TESPA1,HOMER3 |
| 5.665e-03 | -5.17 | skin-leg-malignant_melanoma | COSMIC cancer mutations | skin-leg-malignant_melanoma | 557 | 73 | 17385 | 1698 |
EXPH5,CFH,CNTNAP3,PTPN21,NTRK3,ABAT,FAM13A,DNER,HMCN1,CCNJ,CPNE2,COL22A1,JAKMIP2,SCN2A,TLN2,PTPRE,DNAH5,INTU,TNK2,SESN2,ACVR1C,DCC,PTPRU,LRRC8B,KCNH5,PRKCQ,TNS1,DSP,TMEM132B,ENPP1,TCF7L1,NRG3,ZNF266,PTPRJ,ITGA2,TNFRSF1A,BMP1,PTPRS,ZBTB20,HGF,PPARGC1A,PCDH18,TBC1D1,PTPRD,PLAG1,IPO5,MCTP2,CBS,KCNC4,HSPA12B,CNTN4,CHRM3,SYNPO2,SLC37A1,HNF4G,MSTN,PTPN13,DCHS1,SDK1,SNAP25,SKAP1,KHDRBS2,GALNT14,PLCB1,CTIF,PTPRC,FAT4,ADAMTS3,PLXDC2,PTPRN2,SHOX2,MME,PHC1 |
| 5.674e-03 | -5.17 | negative regulation of apoptotic process | biological process | GO:0043066 | 915 | 111 | 17256 | 1658 |
EPHA3,PRKN,BTC,ID1,ACVR1,GRIK2,DNAJC3,LILRB1,GATA3,NPM1,STAT5B,NTRK3,PRKCA,DDR1,AARS,EYA4,TXNDC5,BAG3,ASNS,MAGEA3,BCL6,CTTN,EPHB6,MET,FANK1,ENO1,POU3F3,DOCK8,SNAI2,PDGFRB,LAMP3,CTH,PRAME,NKX3-2,LRRK2,BNIP3L,YAP1,AGO4,PRKCQ,WNT11,ROR1,ATOH1,FGFR1,SNCA,IRS2,SMAD3,BEX3,SH3RF1,NCKAP1L,PLK2,WFS1,MAP3K21,HGF,ERCC5,ATG5,NRP1,PPARGC1A,UNC5B,RETREG1,MEF2C,BCL11B,PRKAA2,TYRO3,DYRK3,LGALS3,PAK5,GABRB2,ITGA6,DHCR24,SLC25A27,GAS6,TNFRSF10C,EPHB1,SYCP2,BNIP1,IGF1R,GATA2,MYC,PRKCD,PRELID1,SGK3,TFAP2A,LRP6,BNIP3,YBX3,SMAD6,STXBP1,SPRY2,ZNF385A,NOS3,DUSP1,HMGCR,FGFR4,SLC40A1,BDNF,MSX1,NUGGC,NUAK2,FHL2,STRADB,AGAP2,MGMT,HERPUD1,DKK1,CEBPB,TERT,XBP1,PCGF2,BMP4,SFN,TPT1 |
| 5.677e-03 | -5.17 | MTOR_UP.V1_DN | MSigDB lists | MTOR_UP.V1_DN | 173 | 28 | 17377 | 1707 |
PLEKHA5,BACE1,SMARCD3,C1R,RASD1,SLC25A28,CDC42BPA,QPRT,IRS2,NELL2,FBXO32,PDLIM3,MYC,PDE10A,PTPRS,ARL4D,NCAM1,MOXD1,PLTP,CPE,FANK1,LIFR,CSRP2,DDIT3,MED12L,CES3,DUSP1,PHC1 |
| 5.684e-03 | -5.17 | RAMALHO_STEMNESS_DN | MSigDB lists | RAMALHO_STEMNESS_DN | 68 | 14 | 17377 | 1707 |
PTPRC,GSN,ABLIM1,EVL,PRKCB,RGS10,BMP1,PACSIN1,NCAM1,ZDHHC14,NRP1,ADSSL1,CEBPD,CD53 |
| 5.711e-03 | -5.17 | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_UP | 181 | 29 | 17377 | 1707 |
RHOQ,ALDH2,SIDT1,COBLL1,SAV1,SEL1L3,ATP10D,BCL11A,ISG20,ATPAF2,TRIB3,FGR,BACH2,CA2,BACE2,DACT1,EHD3,HK2,OPN3,ADRB1,RAB31,SCRN1,SQLE,CLMN,TNFRSF17,TBC1D9,TSHR,CKAP4,MEF2C |
| 5.711e-03 | -5.17 | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN | 181 | 29 | 17377 | 1707 |
DMXL2,QSOX1,RIN2,ACSL1,LGALS3,KCNQ3,PSTPIP2,MPP1,CYTH3,BLVRB,MSR1,MAFB,IL13RA1,FAM198B,LACC1,WARS,TRPS1,EPB41L3,HPSE,ZNF697,GNB4,EMILIN2,RAB31,SGK3,MARCKS,RNF130,SCN2A,ZNF385A,RNF152 |
| 5.711e-03 | -5.17 | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_DN | 181 | 29 | 17377 | 1707 |
DLGAP1,LPAR2,MEIS2,EDA2R,RNF144A,FASN,GRK6,KIF21B,RNF44,KCNC4,COL14A1,JAM3,HOPX,ZNF711,EPCAM,ZNF266,FRY,NCAM2,AKT3,PCBP4,STC2,TFAP2A,NAP1L3,SP140,IPCEF1,GFI1,HOXB9,RPS23,TPT1 |
| 5.726e-03 | -5.16 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_UP | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_UP | 189 | 30 | 17377 | 1707 |
CRIM1,RAPGEF2,PTPN13,BLVRB,ZDHHC15,UBAC2,GABRR2,C3orf70,CD7,KBTBD11,TTC28,PGAP1,ATP10D,CHST10,GPLD1,TECPR1,TMEM154,MAP2K6,RASGRF2,SERPINI1,SH3BGRL2,TSPAN13,EPHB6,NRP1,DENND1C,PTPRE,RAPGEF5,IL1RAP,SMPDL3A,AMPD1 |
| 5.726e-03 | -5.16 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_DN | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_DN | 189 | 30 | 17377 | 1707 |
DMXL2,SERINC5,ARAP2,MXI1,DYRK3,ACSL1,ALOX5AP,GRB14,RECK,PSD3,LCP2,SATB1,PFN2,BCL11A,BEX4,DEXI,GSN,ABLIM1,AK1,GYPC,GBP1,MPPED2,KCNS3,SERPINI1,FHIT,TNFSF4,PTPRE,ATP2B4,GAB2,MEF2C |
| 5.726e-03 | -5.16 | GSE7852_TREG_VS_TCONV_LN_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_LN_UP | 189 | 30 | 17377 | 1707 |
ZNF516,ERGIC1,TMEM65,REL,ATP9A,WLS,PTPN13,MPP1,UBASH3B,ADAMTS6,C3orf70,SESN1,HOPX,ENTPD1,ARHGAP21,FBXO32,TMEM154,MYADM,PLAGL1,CNKSR3,MATN2,ZDHHC23,HK2,CCDC122,INPP5F,TANC2,NRP1,TBC1D4,NR3C2,RRAGD |
| 5.726e-03 | -5.16 | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | 189 | 30 | 17377 | 1707 |
CXCR5,UNC5C,MXI1,PXN,LGALS3,MYO10,TBC1D1,MGST3,ZNF565,MEF2B,SDC3,FNDC3A,MFSD6,CRYBG3,CA13,FKBP11,TBC1D19,TRPS1,EBF1,IL17D,KCNMB4,PMEPA1,PCBP4,SMTN,RGS10,SGK1,KLF9,RNF130,FES,RBMS2 |
| 5.726e-03 | -5.16 | GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_DN | MSigDB lists | GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_DN | 189 | 30 | 17377 | 1707 |
CREB3L2,UGT8,BMPR2,ARHGAP22,ATOX1,SETBP1,ARL2,SPATS2L,NHP2,CD40,CPEB1,CHST10,BCL11A,ENTPD1,RALGPS2,BACE2,PRKCB,PPFIBP1,EHD3,SFMBT1,CLMN,INPP5F,TMED9,TBC1D9,TESC,GATM,COL9A2,CKAP4,IGSF3,MEF2C |
| 5.726e-03 | -5.16 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | 189 | 30 | 17377 | 1707 |
FARP1,EHHADH,TES,ZCCHC24,MCOLN3,YPEL2,GTF2IRD1,C3orf70,USP30,PFN2,TXNDC5,DCBLD2,RASSF8,TMEM53,TMEM154,RPS6KA2,PRKCB,AKT3,PLK2,C1orf21,ITGB3,SH3BP4,BDH2,SQLE,SH3PXD2B,RAB27B,MAPK10,ESD,PTPRE,CACNA2D1 |
| 5.726e-03 | -5.16 | GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_UP | MSigDB lists | GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_UP | 189 | 30 | 17377 | 1707 |
RGS16,CELSR1,SCAMP1,FN1,FZD4,SLC39A8,CAPN5,PLXNA2,FASN,CTNNA2,GNAI1,CCNJ,PLS3,TUBB4A,SIPA1L2,MSC,GHR,WWTR1,SREBF1,MAOA,DAB2IP,PAX9,BMPR1A,PLD1,ETV1,SFN,CKAP4,CEBPD,CRYL1,HEY1 |
| 5.736e-03 | -5.16 | LGALS3 (galectin 3) | protein interactions | 3958 | 192 | 31 | 17029 | 1718 |
RPS20,LPAR2,SLC3A2,MRC2,ABCC4,LGALS3,FN1,TRIM16,IPO5,ELMOD1,VIM,SLC7A2,SDK1,SLC1A3,SLC12A6,SLC46A3,HEG1,PTPRJ,RPL12,ITGA2,LAMB1,SERINC2,ACTA2,ADCY6,MFSD4A,SERPINH1,SLC1A5,KIAA1549,FOXA1,CKAP4,ATP2B4 |
| 5.738e-03 | -5.16 | V$GR_Q6_01 | MSigDB lists | V$GR_Q6_01 | 254 | 38 | 17377 | 1707 |
TYRO3,SV2B,AMOTL1,ELOVL4,SEC24D,AKAP5,ATP8A1,OTX1,FAM198B,APBA1,NUP62CL,PRRG4,PPP2R3A,TUBB4A,EPB41L3,KCTD15,SLC7A11,AKAP7,BHLHA15,PCBP4,ATRNL1,SMAD6,FANK1,RNF152,BCL7A,GPM6A,PXN,PACSIN3,PRDM1,MBNL2,MAP1B,DLG2,DLX2,TPM1,CDH2,MBOAT2,CTNND2,FOXA1 |
| 5.765e-03 | -5.16 | ELAVL1 (ELAV like RNA binding protein 1) | protein interactions | 1994 | 1780 | 211 | 17029 | 1718 |
EXPH5,TRIM2,LSM11,UGDH,FAM102B,ENAH,CEBPA,PRKCA,OTULINL,NUP62CL,TENT5C,STK24,NCS1,HECTD2,F3,CCNJ,CYP51A1,FKBP9,CDR2L,TGFBR3,KCNAB1,PMAIP1,MARVELD2,RAP2A,TRPC1,HRK,CTTN,EIF4E3,PNRC1,CEMIP2,KLHL3,TGFA,JPH1,NFIA,YAP1,COTL1,PLEKHA1,SAV1,ZDHHC14,SFXN1,SLC7A1,INSIG1,FAM114A2,ATP7B,TNFRSF1A,ZBTB20,TPM1,PXDC1,TC2N,CRYL1,LPP,UST,LATS2,FN1,ZNF395,FBXO4,JDP2,UBASH3B,MFSD13A,TJP1,ZIC2,SCD,CHSY1,GAS1,GRPEL2,MECOM,RNF141,GALNT1,RSL24D1,NAV1,KIAA0895,MSMO1,GATA2,MYC,FAM107B,SRGAP1,LIMCH1,FAM84B,DENND1C,VGLL4,TSPAN9,CKAP4,NOS3,BDNF,RHOQ,B3GLCT,MGST3,ARID5B,TMTC4,STRADB,PRDM1,MBNL2,GLCE,MAPKAPK2,TMCO3,HK2,RAB31,INHBE,IQSEC2,FBXO27,RNF122,PANK3,CREB3L2,PRKN,TCTN2,SCAMP1,RBFOX2,PLEKHA5,HECW2,IL13RA1,CHUK,CANX,FAM110B,SLC19A2,RNF150,EPB41L3,ZNF362,PDZD8,TENT5A,KAZN,PPFIBP1,REEP1,ADGRL1,ZNF521,MARCKS,SERPINH1,SNX10,TMEM56,CTH,DZANK1,GCA,LRRC75A-AS1,TMEM65,TES,C3orf52,PANK1,SATB2,ATP1B1,C1orf174,DCBLD2,IRS2,CAMK2N1,SLC39A14,IGIP,INPP4B,DUSP19,FAAP20,P4HA1,KLF5,GRB10,ATG5,MID1,HEY1,FARP1,ARHGEF11,NSUN6,IGF2BP2,COL4A5,FAM117B,GPR180,SFXN3,NDFIP2,NEO1,MCU,GAS2L3,PRKCD,STC2,TFAP2A,SGK1,MTURN,TSPAN13,KLF9,IQGAP3,ERRFI1,YBX3,SMAD6,SPRY2,FKBP14,RIN2,KDM5B,FOXN3,NUAK2,LITAF,PRRG1,AK4,PHACTR2,RACK1,FNDC3A,ZNF714,CTIF,MKX,RERE,CEBPB,DDAH1,TIFA,MYADM,CLDN12,SLC7A5,PCGF2,SLC18B1,TUFT1,KIF21A,THAP10,SHOX2,MAP3K20,KIF1B,FOXA1,LARP1,BTRC,ABCG1,PHC1 |
| 5.767e-03 | -5.16 | FERM_central | interpro domains | IPR019748 | 48 | 11 | 18492 | 1811 |
FRMPD3,EPB41L5,EPB41L3,PLEKHH2,FARP1,MYO10,PTPN13,PTPN21,FERMT2,TLN2,FRMD5 |
| 5.783e-03 | -5.15 | insulin-like growth factor I binding | molecular function | GO:0031994 | 13 | 5 | 17224 | 1680 |
IGF1R,IGFBP6,ITGA6,ITGB3,IGFBP3 |
| 5.790e-03 | -5.15 | actin-mediated cell contraction | biological process | GO:0070252 | 84 | 16 | 17256 | 1658 |
EPB41L5,SCN5A,KCNN2,SCN1B,CACNB2,ANK2,FGF12,RYR2,PKP2,VIM,KCND3,TPM1,NEB,SHTN1,CACNA2D1,GJC1 |
| 5.819e-03 | -5.15 | parathyroid | COSMIC cancer mutations | parathyroid | 487 | 65 | 17385 | 1698 |
TFCP2L1,LANCL3,PTPN21,KIAA1217,TNKS1BP1,DOCK2,ZFYVE9,SP8,TRPS1,CYP51A1,POU5F1B,TACC2,RAB27B,TLN2,PTPRE,DNAH5,GATM,NEB,TBC1D8,GPM6A,ERGIC1,B3GALT1,CYB5R2,ACO1,NFE2L1,FRK,ZNF569,ARMC4,LAMB1,B3GALT2,ERCC5,HGF,UNC5B,KIF5C,TJP1,ARHGAP44,ZNF354A,ADCK1,EHD3,PRKCD,PRKG1,GRIP1,LIMCH1,DYNC2H1,ALPK1,CKAP4,ATP2B1,MN1,HBG2,SH3BP2,CRIM1,ARID5B,GPSM1,PRRG1,SLITRK5,OBSCN,NEGR1,ZIC1,TMEM237,FAT1,EMILIN2,NXPH4,MMP16,NUDT17,ACSM3 |
| 5.828e-03 | -5.15 | PTPc | smart domains | SM00194 | 37 | 10 | 9493 | 1056 |
PTPRC,PTPRJ,PTPRU,PTPRD,PTPN13,PTPN6,PTPN21,PTPRS,PTPRN2,PTPRE |
| 5.831e-03 | -5.14 | cellular protein localization | biological process | GO:0034613 | 1388 | 161 | 17256 | 1658 |
EXPH5,THOC5,CACNG3,UGT8,FGF13,GRIK2,NPM1,SNX9,NUP62CL,TRPS1,ADPRHL1,SEC16B,PMAIP1,RAP2A,RAB26,NDUFB8,TBC1D32,LIN7A,TMED9,CTTN,COG3,TLN2,PACSIN1,MYRIP,CPE,TBC1D8,DBN1,GDAP1,ITGB7,KCNIP3,WLS,ANK2,LRRK2,ZDHHC14,GSN,INSIG1,TNFRSF1A,NRP1,MAGI2,RRAGD,CELSR1,HID1,SEC24D,TBC1D1,STXBP6,APBA1,BBS9,RPL13A,GRPEL2,CACNB2,RPS11,LRP6,STXBP1,RPS23,RIMS2,BOD1,RPL26,MID2,TBC1D8B,DCHS1,RYR2,OBSCN,STRADB,HIP1,PEX5L,SNAP25,HERPUD1,SPATA7,TBC1D2,RPL28,FCHO2,WDR19,SH3BP4,RAB31,HK2,CDH2,TESC,SIX2,PRKN,ID1,AKAP5,TMSB15A,RHOD,PKP2,NRXN1,PIBF1,TBC1D30,ZFYVE9,SCIN,EPB41L3,ZDHHC6,REEP1,ZDHHC23,BCL6,MAP7,RTKN2,RAB27B,SNX10,KCNB2,RPS13,DPP10,NOP53,PTPRU,WNT11,RAB38,SYNJ2BP,PYGO1,ATP1B1,TBC1D16,RANBP2,KPNA3,GBP1,SEPT5,MID1,RAB30,THOC3,RPS20,TNIK,TSPAN15,LRP4,IPO5,UBAC2,ARL2,KIF5C,GAS6,P2RY1,TSPAN17,ARHGAP44,NEDD4,RPL34,MAP1A,EHD3,PRKG2,SH3PXD2B,DYNC2H1,TBC1D9,MYO6,SEPT3,RAB3B,MSX1,RAB6B,RAPGEF2,RPL21,ZDHHC15,FERMT2,PRICKLE1,SKAP1,RERE,HOMER3,RPL12,MYADM,TERT,NACC2,DLG2,RPL4,HK1,BMP4,RPS12,TBC1D4,KIF1B,DDIT3 |
| 5.832e-03 | -5.14 | GO_TUBE_MORPHOGENESIS | MSigDB lists | GO_TUBE_MORPHOGENESIS | 321 | 46 | 17377 | 1707 |
EFNB2,ACVR1,CELSR1,LGR4,ST14,GATA3,OVOL2,DDR1,SKI,SETDB2,DACT1,MYC,LRP6,DAB2IP,MET,SPRY2,SLIT2,PRKACB,GLI1,FZD1,NKX2-1,PAK1,EPB41L5,MICAL2,KDM5B,KLHL3,DCHS1,RYR2,PRICKLE1,YAP1,WNT11,ACVR2B,HOXA1,SMAD3,FAT4,PTK7,CSF1,HOXD13,BMP4,NRP1,SHOX2,COBL,FOXA1,SIX2,BTRC,MEF2C |
| 5.849e-03 | -5.14 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN | 18 | 6 | 17377 | 1707 |
CHAC1,ASNS,SLC7A11,KLHL4,MLF1,ARHGAP22 |
| 5.849e-03 | -5.14 | MAHADEVAN_RESPONSE_TO_MP470_DN | MSigDB lists | MAHADEVAN_RESPONSE_TO_MP470_DN | 18 | 6 | 17377 | 1707 |
ATF3,CTTN,GEM,MYC,DDIT3,DUSP1 |
| 5.849e-03 | -5.14 | PLASARI_NFIC_TARGETS_BASAL_DN | MSigDB lists | PLASARI_NFIC_TARGETS_BASAL_DN | 18 | 6 | 17377 | 1707 |
EPHA3,IGFBP6,INSIG1,PIK3AP1,SLIT2,STARD4 |
| 5.849e-03 | -5.14 | GO_PROLINE_RICH_REGION_BINDING | MSigDB lists | GO_PROLINE_RICH_REGION_BINDING | 18 | 6 | 17377 | 1707 |
YAP1,RABAC1,NEDD4,APBB1,BAIAP2,GHR |
| 5.849e-03 | -5.14 | NIELSEN_LEIOMYOSARCOMA_CNN1_UP | MSigDB lists | NIELSEN_LEIOMYOSARCOMA_CNN1_UP | 18 | 6 | 17377 | 1707 |
GABRG2,ACTA2,SVIL,TRDMT1,SORBS1,RIMS2 |
| 5.849e-03 | -5.14 | GO_DENDRITE_MEMBRANE | MSigDB lists | GO_DENDRITE_MEMBRANE | 18 | 6 | 17377 | 1707 |
GABRG2,ATF4,AKAP5,WLS,ATP2B1,GABARAPL1 |
| 5.870e-03 | -5.14 | head morphogenesis | biological process | GO:0060323 | 36 | 9 | 17256 | 1658 |
MSX1,ARID5B,LRP6,PLEKHA1,PAX9,ASPH,CRISPLD1,SKI,DKK1 |
| 5.872e-03 | -5.14 | NFE2L2.V2 | MSigDB lists | NFE2L2.V2 | 415 | 57 | 17377 | 1707 |
GPT2,TRIM16L,LANCL3,STXBP5L,PTPRD,JDP2,RIMKLA,UGDH,ACTL8,KIF5C,CBS,CHAC1,BCAN,PHGDH,ABHD4,TPD52L1,PFN2,IL18R1,NEDD4,TXNRD3,NUMBL,ASNS,SLC7A11,PPFIA2,STC2,REEP1,KIAA0319,SREBF1,MPPED2,HRK,RTKN2,PCK2,SLCO4C1,JAKMIP3,TLR4,SYK,POU3F3,CKAP4,IGFBP3,PCSK6,SMAD9,STAT4,MARS,WNT11,SHISA2,ABCC2,PALLD,ZNF714,TSKU,TMEM237,MAP2,TDO2,TERT,C1orf21,ARHGAP28,TNFSF15,SFN |
| 5.873e-03 | -5.14 | SH2_dom_sf | interpro domains | IPR036860 | 112 | 20 | 18492 | 1811 |
RIN2,FER,VAV3,SH3BP2,INPPL1,SH2D2A,GRB14,PTPN6,STAT4,TNS1,STAT5B,LCP2,FRK,CHN1,CHN2,FGR,SHF,GRB10,SYK,FES |
| 5.886e-03 | -5.14 | ZU5_dom | interpro domains | IPR000906 | 13 | 5 | 18492 | 1811 |
UNC5C,TJP1,UNC5B,ANK2,SH3BP4 |
| 5.896e-03 | -5.13 | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | MSigDB lists | SASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION | 48 | 11 | 17377 | 1707 |
QSOX1,ID3,PLOD2,FBN1,VLDLR,TNFRSF1A,RGS10,ATP1B1,DDR1,PDGFRB,CEBPD |
| 5.896e-03 | -5.13 | ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_DN | 48 | 11 | 17377 | 1707 |
DMXL2,ELOVL4,MYC,GDPD1,SERPINI1,GSTO1,BMPR1A,RNF130,FAM162A,RASGRP1,GLCE |
| 5.896e-03 | -5.13 | GO_DIGESTIVE_TRACT_MORPHOGENESIS | MSigDB lists | GO_DIGESTIVE_TRACT_MORPHOGENESIS | 48 | 11 | 17377 | 1707 |
SMAD3,EPB41L5,DACT1,HOXD13,WNT11,ACVR2B,BMP4,OVOL2,SHOX2,SIX2,GLI1 |
| 5.906e-03 | -5.13 | V$NGFIC_01 | MSigDB lists | V$NGFIC_01 | 238 | 36 | 17377 | 1707 |
BCL11B,LRFN5,NUDT10,LANCL3,BMPR2,REL,UBASH3B,OTX1,BCL6B,NTRK3,COL27A1,ZNF827,SLC22A17,KCNN2,RALGPS2,STC2,BCL6,KCNS3,SHF,HRK,PJA1,NDUFA4L2,GPR176,BDNF,ATL1,CACNA1E,JPH1,NFE2L1,ELMOD1,SNAP25,GUCY1A2,UCHL3,SMAD3,DAGLA,CDH2,MEF2C |
| 5.933e-03 | -5.13 | GO_AMEBOIDAL_TYPE_CELL_MIGRATION | MSigDB lists | GO_AMEBOIDAL_TYPE_CELL_MIGRATION | 150 | 25 | 17377 | 1707 |
EPB41L5,EFNB2,SEMA6B,ITGB7,AMOTL1,ACVR1,ID1,NR4A1,ARID5B,WNT11,TNS1,OVOL2,PKN1,SEMA6A,CENPV,GPLD1,SEMA4F,PKN3,SEMA3C,NRP1,SEMA3A,SLIT2,SEMA6C,CYP1B1,NOS3 |
| 5.946e-03 | -5.13 | FYN (FYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 2534 | 240 | 37 | 17029 | 1718 |
EPHA3,TYRO3,PTPRD,ADD2,NDFIP2,LCP2,NEDD4,NOS1AP,RPS6KA2,PRKCD,PDE4D,NCAM1,ENO1,PTPRE,SYK,PDGFRB,TNK2,PXN,EVL,SH3BP2,CD55,SKAP2,DCC,LRRIQ1,SDC3,PRKCQ,ARHGAP32,RACK1,SKAP1,FRK,SNCA,PTPRC,MAP2,TNFRSF1A,GRB10,CTNND2,CNTN1 |
| 5.951e-03 | -5.12 | femur | COSMIC cancer mutations | femur | 1235 | 147 | 17385 | 1698 |
PHACTR3,ACSL1,CACNG3,TCP11L2,CNTNAP3,KIF5A,DOCK3,KIAA1217,HMCN1,PCDH7,BAG3,SIPA1L2,SEC16B,ZFYVE28,AKAP7,PPFIA2,COL19A1,ATRNL1,COG3,TLN2,SLIT2,PRKACB,GLDC,ABCC2,SPNS1,CCBE1,RASGRF2,CCDC146,TNFRSF1A,ARHGAP28,BBC3,PIK3C2B,TMEFF2,MLLT3,HS6ST3,GPT2,MRC2,STXBP5L,OLAH,ATP6V1E2,GALNT13,WDFY4,APBA1,HSPA12B,MTUS1,CNTN4,RALGPS2,FAM189A1,PAIP2B,PIK3AP1,ADCY6,TOX,SLCO4C1,RNF148,FMNL2,CAND2,IGSF3,UNC5C,COL4A4,DCHS1,PACSIN3,OBSCN,HIP1,B4GALNT3,TBC1D2,GRIK4,TMEM154,PELI2,THBS4,FAT1,SQLE,TMEM117,CDH2,OSBPL6,MME,DMXL2,DNM3,NEK10,PLEKHA5,LRRCC1,PLXNA2,PPP1R9A,ZSCAN5A,GPR15,TACC2,COL25A1,ZDHHC23,ZNF521,MYO3B,MYH15,FHIT,NTNG1,COL6A2,ADCY1,PREX1,FGF12,DOCK5,ZNF618,MAGI3,ARMC4,RANBP2,NRG3,PRKCB,TMPRSS9,WFS1,WWTR1,BMPR1A,COBL,DENND5B,MYO1D,C2orf88,WDR17,CKAP2,UBAC2,NSUN6,CLSTN2,NKAIN2,CREB5,COL27A1,FSD1,MAP1A,KIAA0319,AFAP1L2,SH3PXD2B,ERRFI1,FKBP14,ARHGEF28,HNF4G,CACNA1E,NUAK2,RASA3,MARS,PALLD,SNTB1,HOMER3,HEG1,PTPRC,FAT4,PLOD2,FBN1,ZNF214,THSD7B,MCC,KIF21A,HK1,KIF1B,FILIP1 |
| 5.959e-03 | -5.12 | atrioventricular valve development | biological process | GO:0003171 | 24 | 7 | 17256 | 1658 |
BMPR1A,ACVR1,BMPR2,SMAD6,HEYL,DCHS1,HEY1 |
| 5.959e-03 | -5.12 | regulation of homotypic cell-cell adhesion | biological process | GO:0034110 | 24 | 7 | 17256 | 1658 |
PRKCQ,ABAT,PRKCA,SYK,UBASH3B,PRKCD,PRKG1 |
| 5.963e-03 | -5.12 | GO_NEGATIVE_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_HUMORAL_IMMUNE_RESPONSE | 13 | 5 | 17377 | 1707 |
CD55,SUSD4,SPINK5,PTPN6,C4BPB |
| 5.963e-03 | -5.12 | MCCLUNG_CREB1_TARGETS_UP | MSigDB lists | MCCLUNG_CREB1_TARGETS_UP | 97 | 18 | 17377 | 1707 |
BDNF,TTC39B,PTPRD,MGST3,FGF12,PLS3,SIPA1L2,IDI1,SH3GL2,NACC2,SCN1B,ADCY6,LAPTM4B,SERPINI1,MPDZ,MMP16,CRYL1,MEF2C |
| 5.992e-03 | -5.12 | GO_UDP_GLYCOSYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_UDP_GLYCOSYLTRANSFERASE_ACTIVITY | 127 | 22 | 17377 | 1707 |
CHSY3,CCDC126,GXYLT2,GCNT2,UGT8,B3GALT1,GALNT6,GALNT12,XYLT1,MGAT4B,GALNT13,MGAT5B,CHSY1,B4GALNT3,GALNT14,GALNT3,GBGT1,GALNT1,MGAT1,B3GALT2,B4GALT7,B4GALT6 |
| 5.992e-03 | -5.12 | KEGG_TIGHT_JUNCTION | MSigDB lists | KEGG_TIGHT_JUNCTION | 127 | 22 | 17377 | 1707 |
CGN,RAB3B,AMOTL1,TJP1,PRKCQ,PRKCA,JAM3,CTNNA2,MAGI3,GNAI1,EPB41L3,PRKCB,AKT3,PRKCD,MPDZ,MYH15,PPP2R2B,CTTN,RRAS2,MAGI2,JAM2,OCLN |
| 5.999e-03 | -5.12 | positive regulation of JNK cascade | biological process | GO:0046330 | 122 | 21 | 17256 | 1658 |
PAK1,TNIK,EDA2R,FZD4,FZD8,PKN1,PLCB1,TPD52L1,TNFRSF19,TLR6,DKK1,TLR3,ERN1,DUSP19,MAP3K21,DAB2IP,SEMA3A,TNFRSF11A,SYK,MAP3K20,RASGRP1 |
| 5.999e-03 | -5.12 | regulation of fat cell differentiation | biological process | GO:0045598 | 122 | 21 | 17256 | 1658 |
TRPM4,JDP2,GATA3,CEBPA,RARRES2,ZFPM2,SAV1,CEBPB,SMAD3,TRIB3,ENPP1,INSIG1,GATA2,WWTR1,XBP1,C1QL4,KLF5,SH3PXD2B,ZFP36L2,ZNF385A,DDIT3 |
| 6.009e-03 | -5.11 | GUANYLATE_KINASE_2 | prosite domains | PS50052 | 22 | 7 | 12060 | 1278 |
DLG2,TJP1,MPP7,MAGI2,MPP1,MAGI3,MPP2 |
| 6.015e-03 | -5.11 | Platelet activation | KEGG pathways | hsa04611 | 123 | 22 | 7161 | 730 |
PLA2G4A,MYLK3,VAMP8,ADCY1,P2RY1,ITPR2,GUCY1A2,LCP2,PLCB1,GNAI1,AKT3,ITGB3,ITGA2,PRKG1,ADCY6,PRKG2,MAPK13,TLN2,SYK,PRKACB,RASGRP1,NOS3 |
| 6.023e-03 | -5.11 | Lin7c (lin-7 homolog C (C. elegans)) | protein interactions | 22343 | 23 | 7 | 17029 | 1718 |
YAP1,MPDZ,AMOTL1,MPP7,MGST3,WWTR1,PATJ |
| 6.031e-03 | -5.11 | GO_POSITIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 158 | 26 | 17377 | 1707 |
EPB41L5,BDNF,DISC1,GCNT2,FN1,ROBO2,BMPR2,PTPRD,AKAP5,PREX1,NTRK3,AMIGO1,RAC3,BAIAP2,MAP1B,BCL11A,SMAD3,RND2,NUMBL,MYADM,WWTR1,SGK1,MARCKS,NRP1,SHOX2,SLIT2 |
| 6.043e-03 | -5.11 | GO_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS | MSigDB lists | GO_CELLULAR_COMPONENT_ASSEMBLY_INVOLVED_IN_MORPHOGENESIS | 222 | 34 | 17377 | 1707 |
UGT8,TCTN2,CELSR3,PIBF1,BBS9,TTC30B,FHOD3,EPB41L3,ABLIM1,LRRC6,EHD3,FIG4,DYNC2H1,DNAH5,SNX10,PDGFRB,B9D1,INTU,DISC1,MYLK3,TMEM67,ABCC4,SPATA6,ANK2,OBSCN,TTC30A,ARMC4,IFT81,TMEM237,WDR19,DYNC2LI1,TMOD2,TPM1,FNBP1L |
| 6.043e-03 | -5.11 | GO_RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | GO_RAS_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 222 | 34 | 17377 | 1707 |
BTC,FARP1,ARHGEF11,DOCK1,DENND3,DOCK2,TIAM2,ARHGEF10L,MCF2L,NCAM1,DENND1C,GFRA1,RAPGEF5,RASGRP1,PDGFRB,FGFR4,VAV3,RIN2,MCF2L2,RAPGEF2,RAPGEF4,SPATA13,PREX1,OBSCN,FGF17,SERGEF,ARHGEF26,FGFR1,IRS2,RASGRF2,ADRB1,PLEKHG1,GRIN2D,DENND5B |
| 6.063e-03 | -5.11 | GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 112 | 20 | 17377 | 1707 |
SEMA6B,DNM3,ID1,FGF13,DCC,RAPGEF2,LRP4,OVOL2,SEMA6A,BCL11A,SEMA4F,GBP1,DAB2IP,SEMA3C,NRP1,SEMA3A,SLIT2,SEMA6C,FOXA1,NKX2-1 |
| 6.063e-03 | -5.11 | GO_EAR_MORPHOGENESIS | MSigDB lists | GO_EAR_MORPHOGENESIS | 112 | 20 | 17377 | 1707 |
MSX1,CELSR1,NKX3-2,OTX1,GATA3,MAFB,ATOH1,HOXA1,FGFR1,ZIC1,INSIG1,GATA2,PDZD7,DLX6,PTK7,WDR19,TFAP2A,NRP1,SPRY2,SIX2 |
| 6.082e-03 | -5.10 | protein serine/threonine/tyrosine kinase activity | molecular function | GO:0004712 | 42 | 10 | 17224 | 1680 |
SGK1,PRKAA2,DYRK1B,TNK2,ACVR2B,DYRK3,RPS6KA2,MAPK10,MAP2K6,LRRK2 |
| 6.085e-03 | -5.10 | positive regulation of sodium ion transport | biological process | GO:0010765 | 30 | 8 | 17256 | 1658 |
SCN5A,SCN1B,CNKSR3,FGF12,PKP2,ATP1B1,TESC,CNTN1 |
| 6.102e-03 | -5.10 | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP | 166 | 27 | 17377 | 1707 |
MAN2B2,BMPR2,ITPRIP,DNAJC3,ITGA6,EFHC2,YPEL2,ABHD13,SELL,RNF125,RASA3,PRKCQ,ASPH,MECOM,IRS2,OTUD1,ARHGAP21,PTPRJ,PELI2,WDR19,SGK1,TOX,SUSD4,VWA5A,LRRC27,DNAH5,DUSP1 |
| 6.103e-03 | -5.10 | PTPc_motif | smart domains | SM00404 | 61 | 14 | 9493 | 1056 |
PTPRC,PTPRJ,PTPRU,CDC14B,PTPRD,PTPN6,PTPN13,PTPN21,PALD1,PTPRN2,PTPRS,TNS1,PTPRE,DUSP1 |
| 6.116e-03 | -5.10 | positive regulation of JUN kinase activity | biological process | GO:0043507 | 70 | 14 | 17256 | 1658 |
PAK1,TNIK,FZD4,FZD8,ERN1,MAP3K21,DUSP19,DAB2IP,PKN1,TLR6,TNFRSF11A,SYK,MAP3K20,DKK1 |
| 6.142e-03 | -5.09 | SH3DOMAIN | prints domains | PR00452 | 83 | 16 | 4652 | 458 |
VAV3,SORBS1,SKAP2,PACSIN3,SORBS3,SKAP1,FRK,FGR,SH3GL2,SH3RF1,MPP7,ABI3,MAP3K21,CTTN,PACSIN1,NEB |
| 6.149e-03 | -5.09 | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP | 174 | 28 | 17377 | 1707 |
RUNX2,PTPN13,DSTN,TUBE1,HIP1,COBLL1,PHACTR2,VIM,PRDM1,CHSY1,ATOH1,DOCK5,IL18R1,SMPDL3B,GABARAPL1,HOPX,GALNT3,PTPRJ,MYADM,PIK3AP1,PMAIP1,ERN1,RAP2A,HK2,GEM,ATG5,SNX10,ATP2B4 |
| 6.149e-03 | -5.09 | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | 174 | 28 | 17377 | 1707 |
TNK2,MYO1D,TNIK,RGS16,PXN,ERGIC1,PDE1B,BMPR2,PFKFB2,TBC1D1,YPEL2,NFIA,SDC3,NPC2,GUCY1A2,TTC28,DDIT4,HEG1,SLC7A1,SLC22A17,IGIP,MCF2L,CLDN12,TFAP2A,TSC22D1,CAB39L,DCBLD1,CES3 |
| 6.149e-03 | -5.09 | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN | 174 | 28 | 17377 | 1707 |
GAPDH,RUNX2,NR4A1,DSTN,ATOX1,COBLL1,PRDM1,CHSY1,DOCK5,IL18R1,SMPDL3B,GABARAPL1,HOPX,GALNT3,ENTPD1,PTPRJ,MYADM,PIK3AP1,PMAIP1,RAP2A,PCGF2,MED7,GEM,NRP1,ERRFI1,SNX10,PERP,ATP2B4 |
| 6.165e-03 | -5.09 | GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | 198 | 31 | 17377 | 1707 |
GSTM2,LGALS3,AKAP5,ANK2,UBASH3B,PTPN6,JPH1,PACSIN3,LILRB1,RYR2,GSTO1,ATP1B1,CACNB4,ASPH,NOS1AP,SNCA,CXCL10,CACNB2,GNAO1,WFS1,STC2,TRPC1,TSPAN13,PDE4D,BMP4,ATG5,TRPC3,HSPA2,CACNA2D1,PDGFRB,NOS3 |
| 6.167e-03 | -5.09 | membrane depolarization | biological process | GO:0051899 | 63 | 13 | 17256 | 1658 |
TRPM4,SCN5A,ATP5IF1,SCN1B,CACNB2,CACNA1E,SCN8A,ANK2,CHRNA6,SCN2A,CACNB4,CACNA2D1,SCN3A |
| 6.169e-03 | -5.09 | Insulin Signaling | WikiPathways | WP481 | 161 | 28 | 5312 | 569 |
PRKAA2,SORBS1,RHOQ,INPPL1,GRB14,CYTH3,PRKCQ,MAPK4,SNAP25,PRKCA,SGK2,IRS2,TRIB3,ENPP1,RPS6KA2,IGF1R,PRKCB,MAP2K6,EIF4EBP1,XBP1,PRKCD,SGK3,SGK1,MAPK13,GRB10,TBC1D4,MAPK10,STXBP1 |
| 6.173e-03 | -5.09 | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_DN | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_DN | 182 | 29 | 17377 | 1707 |
C2orf88,PLBD2,TMEM65,CYTH3,PANK1,RASA3,IL13RA1,SCD,CD7,ATP10D,HERPUD1,PLS3,RTN1,ENTPD1,CXCL10,RNF180,GYPC,KPNA3,AKT3,PLXDC2,RUNDC3B,DUSP19,LRP6,RPL4,RNF122,TNFRSF11A,PRKACB,CTNND2,LPP |
| 6.173e-03 | -5.09 | GSE2585_THYMIC_DC_VS_MTEC_UP | MSigDB lists | GSE2585_THYMIC_DC_VS_MTEC_UP | 182 | 29 | 17377 | 1707 |
MXI1,PRSS16,PTPRD,NKX3-2,RPL21,NFE2L1,RNF24,ZBBX,AARS,DOK5,PPP1R9A,CD53,SNCA,CHRNA5,ADAMTS3,PTPRN2,COL19A1,MYOM2,BMPR1A,MED7,ST8SIA1,TPM1,TMEM120B,ETV1,IL9R,PERP,RRAGD,DUSP1,NKX2-1 |
| 6.173e-03 | -5.09 | GSE37532_WT_VS_PPARG_KO_LN_TCONV_UP | MSigDB lists | GSE37532_WT_VS_PPARG_KO_LN_TCONV_UP | 182 | 29 | 17377 | 1707 |
WDR17,RNF170,FOXN3,SPATA6,CYTH3,DCHS1,YPEL2,NPC2,PLEKHA1,SLC12A6,MFSD6,SESN1,C4BPB,HECTD2,KCNMB4,RALGPS2,TRIM34,BACH2,CNKSR3,NCOA7,ZDHHC23,AHNAK2,SVIL,INPP5F,DBP,RNF130,IPCEF1,FILIP1,SMPDL3A |
| 6.173e-03 | -5.09 | GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP | 182 | 29 | 17377 | 1707 |
ITGB7,GXYLT2,AVPI1,PNP,BACE1,IL13RA1,PRKAR2B,AIG1,SPATS2L,COTL1,NPC2,SFXN3,CANX,PALLD,DOCK5,HERPUD1,SPIRE1,HOPX,PRTFDC1,PLAGL1,SCRN1,CNNM2,PTPRS,LAPTM4B,STEAP3,NAP1L3,BNIP3,SLC22A15,JAM2 |
| 6.173e-03 | -5.09 | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN | MSigDB lists | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN | 182 | 29 | 17377 | 1707 |
PAK1,ALOX5AP,LPCAT2,MPP1,GPR65,ITGA6,DEPTOR,EDEM3,OPHN1,PLXNA2,BNIP3L,PRRG1,ITPR2,GAS6,SLC12A6,ZDHHC14,DOCK5,ABHD4,GSN,TIFA,EEF2,BACH2,NACC2,GPR155,TECPR2,TMEM86A,HPGD,SYK,RRAGD |
| 6.173e-03 | -5.09 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_UP | 182 | 29 | 17377 | 1707 |
BCL11B,TFCP2L1,RAB3B,CACNG3,EDA2R,FLVCR2,ESRRG,SHANK2,RAPGEF4,MCOLN3,TDRKH,PLS1,ACVR2B,SEZ6L2,SNTB1,HEG1,RALGPS2,MCF2L,STC2,RAI14,GRB10,MYH15,ST8SIA1,ETV1,NEUROG2,MYT1,SHOX2,LIFR,IL1RAP |
| 6.173e-03 | -5.09 | GSE23321_CD8_STEM_CELL_MEMORY_VS_CENTRAL_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_CENTRAL_MEMORY_CD8_TCELL_UP | 182 | 29 | 17377 | 1707 |
PCDH18,NBL1,AASS,ACVR1C,KCNH5,PLAG1,WNT11,COLEC10,DOCK3,HERPUD1,BATF3,EFEMP1,EBF1,NRG3,GTSF1,MCF2L,LHX6,MAP9,SMTN,SCRN1,SCN2A,SPRED3,PPARGC1A,SUSD4,KLHL29,TMEM120B,TSPAN9,PRR16,NUDT17 |
| 6.173e-03 | -5.09 | GO_POSITIVE_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_CATION_TRANSMEMBRANE_TRANSPORT | 90 | 17 | 17377 | 1707 |
GSTM2,ANK2,RYR2,GSTO1,AMIGO1,ATP1B1,ASPH,NOS1AP,SNCA,CXCL10,AKAP7,CACNB2,TRPC1,BMP4,TESC,HSPA2,CACNA2D1 |
| 6.173e-03 | -5.09 | GO_CANONICAL_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_CANONICAL_WNT_SIGNALING_PATHWAY | 90 | 17 | 17377 | 1707 |
DISC1,LGR4,PTPRU,FZD4,FZD8,LRRK2,GATA3,RYR2,WNT11,TCF7L1,MYC,PTK7,LRP6,HOXB9,SNAI2,GLI1,FZD1 |
| 6.173e-03 | -5.09 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 90 | 17 | 17377 | 1707 |
MYADM,TSPAN15,CACNB2,ANK2,EHD3,TNFRSF1A,RAB26,RAB31,PRKG2,PKP2,GAS6,ATP1B1,PACSIN1,CDH2,TESC,TSPAN17,KCNB2 |
| 6.173e-03 | -5.09 | GO_DORSAL_VENTRAL_PATTERN_FORMATION | MSigDB lists | GO_DORSAL_VENTRAL_PATTERN_FORMATION | 90 | 17 | 17377 | 1707 |
INTU,NBL1,LRP4,RGS20,OVOL2,SP8,NKX6-1,WDR19,LRP6,DISP1,BMP4,BMPR1A,DYNC2H1,SMAD6,FOXA1,GLI1,NKX2-1 |
| 6.178e-03 | -5.09 | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | 190 | 30 | 17377 | 1707 |
GCA,ZNF516,PNRC1,PSTPIP2,RAPGEF2,PLXNA2,PRDM1,LCP2,ABHD6,SMPDL3B,HERPUD1,F3,TRPS1,ISG20,ATXN7L1,FGR,PTPRJ,SLC7A11,GRHL1,SCN1B,RBPMS2,FLRT3,SLC2A6,NCOA7,MET,FNBP1L,TMEM120B,PTPRE,SYK,SLC16A10 |
| 6.178e-03 | -5.09 | GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_UP | 190 | 30 | 17377 | 1707 |
RPS20,DLGAP1,MAN2B2,GCA,TNK2,VNN2,LPAR2,ID1,ITGA6,LITAF,RASA3,GDPD5,COL14A1,DOCK2,RPL34,BCL11A,DDIT4,ISG20,PCDH7,CD37,ABLIM1,CDC14B,MCF2L,FAM168A,RAB31,HPGD,SGK1,KLF5,ZFP36L2,DDIT3 |
| 6.178e-03 | -5.09 | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_UP | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_UP | 190 | 30 | 17377 | 1707 |
CREB3L2,GCA,AVPI1,ZNF516,RHOQ,ATP8A1,MGAT4B,CYP4V2,ACO1,PHACTR2,PDE8A,IL13RA1,ARHGAP32,ISYNA1,TMEM170B,CD40,CRYBG3,CENPV,SMPDL3B,MAPKAPK2,CXCL10,RND3,XBP1,RAP2A,C1orf21,EEPD1,LMAN2,MAPK13,MET,PTPRE |
| 6.178e-03 | -5.09 | GSE21379_TFH_VS_NON_TFH_CD4_TCELL_DN | MSigDB lists | GSE21379_TFH_VS_NON_TFH_CD4_TCELL_DN | 190 | 30 | 17377 | 1707 |
GPT2,PHACTR3,MID2,GCNT2,NECAB2,CYP2J2,EXOC6B,LAMC3,YAP1,OR51B4,SLC2A13,HERC6,FAM110B,TPK1,GPLD1,TEX15,RNF180,KCTD15,IQCH,KLF12,BACE2,PLEKHG1,ARHGAP28,SLC16A9,SEMA3C,CYP2U1,PLD1,MDH1B,MAPK10,TSPAN9 |
| 6.178e-03 | -5.09 | GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DN | MSigDB lists | GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DN | 190 | 30 | 17377 | 1707 |
DPP10,PAK1,UNC5C,TTC39B,SLC27A2,DCC,ELOVL3,PACSIN3,GABRG2,CR2,AIG1,SCD,ZFPM2,FBXO36,LCP2,ZDHHC14,LEPR,HECTD2,COL27A1,TMEM74,TEX15,LRRN1,SLC30A4,PRKCB,TUFT1,OXTR,MDH1B,RNF122,SIX2,C3orf67 |
| 6.178e-03 | -5.09 | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN | 190 | 30 | 17377 | 1707 |
MICAL2,SESN2,AGPAT4,MCTP2,PREX1,TTYH2,TTC22,SPATS2L,SFXN3,ZDHHC14,DENND3,SLCO3A1,HOPX,SMAD3,MCOLN2,TGFBR3,CHN2,EOMES,PIK3AP1,OSBPL5,PAM,JAKMIP2,TMED9,TOX,PPP2R2B,SP140,MYO6,ATP2B4,LPP,STOM |
| 6.187e-03 | -5.09 | GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | MSigDB lists | GO_ESTABLISHMENT_OR_MAINTENANCE_OF_CELL_POLARITY | 135 | 23 | 17377 | 1707 |
UST,AMOTL1,FGF13,ARHGEF11,CAP2,CYTH3,WWC1,WNT11,GPSM2,EPHB1,DOCK2,JAM3,MAP1B,DOCK7,MPP7,NCKAP1L,FAT1,PTK7,RAP2A,MAP7,LIN7A,DLG2,SPRY2 |
| 6.187e-03 | -5.09 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | 135 | 23 | 17377 | 1707 |
RGS16,MXI1,PDK1,ENO2,PNRC1,KIF5A,ALDH1L2,RUSC2,GATA3,ATF3,IL13RA1,PALLD,FAM162A,PLK2,HK2,MPP2,P4HA1,SGK1,BNIP3,ZBTB20,SPRY4,ERRFI1,SPRY2 |
| 6.191e-03 | -5.08 | Myh9 (myosin, heavy polypeptide 9, non-muscle) | protein interactions | 17886 | 193 | 31 | 17029 | 1718 |
DBN1,PDLIM7,CGN,PHLDB2,FARP1,ATP9A,DSTN,TES,MYO1B,PACSIN3,PLS1,TJP1,GSN,ABLIM1,ARHGAP21,FCHO2,PPFIBP1,MCF2L,DSG2,GAS2L3,RAI14,SVIL,ZBTB20,LIMCH1,MYO6,TPM1,RRAS2,STON2,COBL,KIAA1211,HACE1 |
| 6.195e-03 | -5.08 | apical junction complex | cellular component | GO:0043296 | 140 | 23 | 18223 | 1724 |
CGN,AMOTL1,SORBS1,BVES,PARD3B,RAPGEF2,CYTH3,TJP1,JAM3,MAGI3,PATJ,EPCAM,MPP7,MARVELD2,CLDN12,POF1B,LIN7A,MPDZ,YBX3,JAM2,MAGI2,NPHP1,OCLN |
| 6.197e-03 | -5.08 | localization within membrane | biological process | GO:0051668 | 107 | 19 | 17256 | 1658 |
ITGB7,DNM3,CACNG3,GRIK2,SEC24D,KIF5A,CMTM8,LRP4,HIP1,KIF5C,ATP1B1,SNAP25,NRXN1,DOCK2,ARHGAP44,WDR19,DLG2,CDH2,MAGI2 |
| 6.252e-03 | -5.07 | signal release | biological process | GO:0023061 | 178 | 28 | 17256 | 1658 |
DOC2A,SLC6A9,FZD4,SYT12,WLS,RAPGEF4,PPFIA4,GATA3,SNAP25,ACVR2B,SYT14,NRXN1,APBA1,PCLO,ILDR2,RAB11FIP5,TRIM9,UNC13B,PPFIA2,SELENOM,LIN7A,PTPRN2,CADPS2,SEPT5,STXBP1,TC2N,RIMS2,SNPH |
| 6.253e-03 | -5.07 | GO_REGULATION_OF_B_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_B_CELL_PROLIFERATION | 55 | 12 | 17377 | 1707 |
PTPRC,IRS2,VAV3,IKZF3,NCKAP1L,TNFSF13B,BCL6,PRDM1,CD40,PKN1,TLR4,MEF2C |
| 6.253e-03 | -5.07 | PID_FGF_PATHWAY | MSigDB lists | PID_FGF_PATHWAY | 55 | 12 | 17377 | 1707 |
FGFR4,IL17RD,RUNX2,HGF,STAT5B,FGF17,CTTN,MET,NCAM1,CDH2,SPRY2,FGFR1 |
| 6.262e-03 | -5.07 | PSI | interpro domains | IPR016201 | 42 | 10 | 18492 | 1811 |
ITGB7,SEMA4F,PLXDC2,ITGB3,PLXNA2,ATRNL1,SEMA3C,MET,SEMA3A,SEMA6A |
| 6.285e-03 | -5.07 | Regulation of RAC1 activity | Pathway Interaction DB | rac1_reg_pathway | 39 | 11 | 2226 | 278 |
CHN1,VAV3,CHN2,DOCK1,RASGRF2,EPS8,PREX1,SPATA13,DOCK6,DOCK2,TIAM2 |
| 6.295e-03 | -5.07 | coenzyme biosynthetic process | biological process | GO:0009108 | 170 | 27 | 17256 | 1658 |
NMNAT3,ATP5IF1,MOCOS,ACSL1,GAPDH,PNP,ENO2,PFKFB2,ELOVL7,ELOVL3,PANK1,OGDHL,FASN,HACD1,SCD,NUDT12,QPRT,TPK1,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1,PANK3,PARP9 |
| 6.295e-03 | -5.07 | central nervous system neuron differentiation | biological process | GO:0021953 | 170 | 27 | 17256 | 1658 |
BCL11B,ROBO2,DCC,RAPGEF2,OPHN1,SATB2,EPHB1,GDPD5,FOXG1,CHD5,RAC3,CBLN1,TSKU,NKX6-1,EOMES,GATA2,SCN1B,MAP2,LHX6,LRP6,DLX2,DYNC2H1,NRP1,SEMA3A,SLIT2,FZD1,NKX2-1 |
| 6.295e-03 | -5.07 | morphogenesis of a branching structure | biological process | GO:0001763 | 170 | 27 | 17256 | 1658 |
PAK1,ACVR1,CELSR1,KDM5B,ST14,DCHS1,YAP1,PRDM1,DDR1,FGFR1,RERE,FAT4,MYC,CSF1,LRP6,SEMA3C,HOXD13,DLX2,BMP4,MET,NRP1,SEMA3A,SPRY2,SLIT2,FOXA1,BTRC,NKX2-1 |
| 6.309e-03 | -5.07 | intracellular part | cellular component | GO:0044424 | 14262 | 1390 | 18223 | 1724 |
ARHGAP26,TRIM16L,THOC5,ADAL,GRIK2,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,KIAA1217,BCAN,SNX9,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,SMIM20,EIF4E3,KLHL23,DCC,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,INTS6,PYCR1,ZNF788P,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,INPP5F,TPM1,DNHD1,VASH2,SCN5A,ZNF25,TJP1,BTBD9,GPSM2,BBS9,FOXG1,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,TOX,CADPS2,FAM84B,ALPK1,DENND1C,MOXD1,FIGN,ZNF385A,ARID5B,ZNF605,FHL2,FASN,HIP1,ST6GALNAC3,SHISA2,SNAP25,ARRDC4,CLN5,SPATA7,TEX15,RIMKLB,GSTO2,RPL28,QPCTL,SELENOM,CLMN,LAPTM4B,HOXD13,CDH2,SHTN1,GVINP1,DOCK9,MTG1,TFCP2L1,SCAMP1,SUGCT,ABHD13,ADD2,MAPK4,TLR3,ALDH1L1,MAGEA3,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,EBPL,PFKFB2,TRAM1L1,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ARHGAP21,PDLIM3,WFS1,LAMB1,RAB30,CGB2,ANKRD13B,WDR17,GCAT,CKAP2,BACE1,PLAG1,FZD8,ESRP1,BIK,UBAC2,CBS,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,OPLAH,LZTS3,RAB6B,RASA3,AK4,ATP11A,NSD1,RPL12,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,PHC1,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,MGAT5B,FAM13A,CCNJ,PLS3,RND2,CPNE2,RPS6KA2,TM9SF2,SEC16B,AADAT,ITGB3,TBC1D32,TMEM143,JAKMIP2,ENO1,RAPGEF5,ZNF391,PGBD5,DBN1,KCNIP3,MARK1,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,SESN1,SPNS1,DYRK1B,TRIM9,TCF7L1,INSIG1,KLF12,ERN1,AHNAK2,CIART,NEUROG2,TC2N,CACUL1,RRAGD,LONRF1,TYRO3,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZNF215,ZIC2,PFN2,DOK5,FHOD3,SPIRE1,RNF180,GALNT1,NUMBL,ZBTB38,ZNF440,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,FAR2,VGLL4,CKAP4,DPYSL5,NDUFA4L2,B3GLCT,MGAT4B,GPSM1,MAFB,STRADB,OBSCN,KHDRBS2,BAIAP2,TBC1D2,PLD1,RNF122,ID1,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,PRR7,TNKS1BP1,RADIL,PPP1R9A,ZNF362,IDI1,TACC2,BCL6,ZDHHC23,MYH15,SNAI2,IGFBP3,RPS13,INTU,LRRC8B,TMEM65,TDRD3,PRDM13,ACO1,RNF125,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,KIZ,DYRK3,NECAB2,BMPR2,PAK5,KLHL13,MCTP2,RASD1,PRDM8,USP30,TTC1,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,SYK,ATP2B1,CES3,PCSK6,DUSP1,FOXN3,CRIP2,FERMT2,PRICKLE1,EXOG,PALLD,ILDR2,MGMT,HOMER3,DKK1,EBF1,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,PLBD2,LDLR,VAMP8,PRKCA,HECTD2,SLC9A7,TRPS1,TYMP,ZFYVE28,PALD1,KCNS3,NDUFB8,THSD1,GLDC,GDAP1,ERGIC1,KLHL3,WISP3,LRMP,BNIP3L,EFHC1,ZDHHC14,GNAI1,SH3RF1,BMP1,DSEL,MAPK13,SERPINI1,SPRY4,NRP1,KLF8,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,LRRC49,HERC6,APBA1,MTUS1,ABLIM1,SLC7A11,RALGPS2,NOVA2,MYC,SREBF1,PRKG1,GRIP1,MAST4,COL9A2,GPR161,BOD1,RPL26,DISC1,SLC36A1,VLDLR,RAPGEF4,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,PLEKHH2,PELI2,THBS4,CECR2,WDR19,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,RHOD,CCDC110,MSR1,COL14A1,DDR1,TIAM2,ZFYVE9,CCDC120,SPEG,ASNS,ERG28,ZNF438,POU5F1B,ALDOC,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,ATF3,SATB2,CBY1,PYGO1,ATOH1,TRIQK,ATP10D,ISG20,SNCA,PATJ,ZNF711,IKZF3,BEX3,TDO2,CCNA1,ZNF704,HPGD,MID1,STON2,PURG,COBL,HACE1,MYO1D,IGFBP6,EPS8,KIF5C,HERC5,NDFIP2,TPD52L1,INPP1,PHLDA2,ADGRB2,GSAP,IRX5,GPR155,AFF2,RMDN2,DYNC2H1,CERS4,ERRFI1,SMAD6,B4GALT6,SLC40A1,VAV3,PXN,ALDH2,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,TMEM126A,ZDHHC15,UCHL3,HOXA1,ZFP62,TERT,MCC,SVIL,LRRK1,CERS1,DDIT3,LARP1,ACSL1,UGT8,ACTL8,PTPN21,HMCN1,CHST10,GSDME,ADPRHL1,PPM1E,CNNM2,CTTN,MYRIP,PDGFRB,LAMP3,CYP1B1,TNK2,SESN2,SKAP2,JPH1,YAP1,COTL1,SGK2,GSN,TMEM150B,GPRC5B,HPSE,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,SCART1,STXBP6,FBXO4,SCD,CHSY1,SPINK5,EEF2,SLC30A4,ZNF354A,INAVA,CAND2,CEBPD,SNX7,ZNF629,HBG2,ATP5IF1,PODXL2,RHOQ,GSTM4,SDC3,STEAP1,HERPUD1,RIPOR2,PLAGL1,FAT1,SH3BP4,RAB31,TMEM117,PTPRN2,FNBP1L,NKX2-8,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,PPFIBP1,KAZN,REEP1,FABP6,ACVR2A,FHIT,PROS1,TMEM120B,SP140L,ALG10B,PRAME,ANTXR2,PTPN6,MVD,C3orf52,TCEAL3,CD40,CENPV,ZNF569,BCL11A,BATF3,ARMC4,ZNF93,TRIM34,KPNA3,EIF4EBP1,RBPMS2,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,SLX1B,FAM117B,COL4A5,IGF2BP2,OVOL2,SEL1L3,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,IPCEF1,TESPA1,RBMS2,PNMA2,USP2,KDM5B,HNF4G,SYBU,CCDC184,ASAP3,PEAK1,GALNT14,TLR6,NAALADL2,LRAT,CTIF,DPY19L2,SUGT1,ICA1,EDA,RND3,ACER2,CTSV,UACA,RPS12,RNF157,NPHP1,ABCG1,DOC2A,PDE1B,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,PCDH7,EPDR1,BAG3,TGFBR3,PPP1R26,FBXO32,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,ZBED9,NKX2-1,MEIS2,SMAD9,GJB2,TGFA,CAP2,WLS,HACD1,ELMOD1,MSRB3,F12,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,CRYL1,LPP,MEF2C,CARS,LATS2,GNG12,CYP2J2,SLK,SLC36A4,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,ZIC5,PRELID2,ST8SIA1,NCAM1,ZNF518B,STXBP1,GLIS1,AGL,FMNL2,RPS23,HMGCR,FADS1,BDNF,ENAM,SLC37A1,PNP,MYO10,STAT4,MGST3,CALCRL,SMARCD3,RYR2,PLS1,TAF4B,MBNL2,CPEB1,DHX32,BEX4,SH3GL2,CDH17,FBXO27,CSRP2,NUDT10,DNM3,ZNF516,TMSB15A,GALNT12,C4A,GALNT6,MYO1B,LRRCC1,BEGAIN,RGS20,PKP2,LCP2,NRXN1,COLEC10,TXNRD3,CDS1,GPR15,EPB41L3,EEF1AKMT2,KMO,CNKSR3,DACT1,COL25A1,RTKN2,PJA1,RAB27B,SYNGR3,JAKMIP3,ARL4D,PERP,DOCK8,SCN3A,SSH3,GARS,FZD4,NKX3-2,NPM3,ATF7IP2,PXYLP1,RAB38,TTC28,FGFR1,METAP1D,IRS2,GYPC,ZNF697,PEMT,WWTR1,PLEKHG1,INPP4B,PAM,ALG11,P4HA1,RCN3,DBP,KLHL31,HOXB9,SERINC5,FARP1,IPO5,P2RY1,CREB5,PKN1,TSPAN17,COL27A1,NEO1,BHLHA15,MCF2L,GAS2L3,MORN2,MYO6,FES,ULBP1,LCA5,CLYBL,RAPGEF2,ELOVL3,RACK1,SNTB1,PTPRC,GALNT3,TRIB3,ID3,GNAO1,AKT3,XBP1,OSBPL5,HK1,SHOX2,DOCK6,BTRC,FOXA1,TPT1,NMNAT3,NBPF4,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,NUP62CL,NOVA1,FKBP9,KCNAB1,EOMES,KCNN2,HPS1,MARVELD2,COL19A1,TLN2,TLR4,ETV1,NEB,CD55,GCNT2,SLC3A2,ABCC4,GDPD1,PLEKHA1,TCERG1L,BATF,PLEKHB1,MAP2,P4HA2,GNB4,CCDC146,TIGD4,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,UBASH3B,SETBP1,MLC1,PGAP1,KIAA1958,PRTFDC1,SEMA4F,IGF1R,ABCA5,GATA2,BCHE,PDE10A,SAMD11,BNIP3,SLCO4C1,FBXL2,PAK1,FGFR4,CHSY3,MID2,SLC27A2,RNF170,HOMER2,TCEA3,SPATA13,PPFIA4,PDE8A,LDHD,NAP1L5,MAPKAPK2,ATPAF2,CSF1,HEYL,MFSD2A,PANK3,TESC,SIX2,SFN,MME,PRKN,AKAP5,RBFOX2,LPCAT2,XYLT1,ZNF83,RNF24,FAM198B,LPIN3,SEZ6L2,KBTBD11,PCLO,CTNNA2,CYP26A1,FAM131B,RIDA,SLC22A17,ZDHHC6,LHX6,MYO3B,CLVS2,ZNF488,GLI1,CTH,EVL,EVA1A,TMEM67,TUBA1A,UROS,NOP53,FGF12,GSTO1,RARRES2,FRK,ETNPPL,JAM3,SMAD3,RANBP2,GBP1,ABI3,ITGA2,SEPT5,ZNF701,MAN2B2,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,SELL,GABRG2,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,MOB1B,MICAL2,PPP1R3D,NUGGC,LITAF,NUAK2,FNDC3A,MAP10,MKX,L3MBTL4,ZNF214,FMO4,DLG2,ZNF808,MYRF,RPL4,PAX9,TBC1D4,FILIP1,CGN,MYCBP2,PPP4R4,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,RAC3,DACH2,AARS,NCS1,STK24,MOK,SLC22A18,CHRDL1,GSTM3,SP140,VWA5A,PACSIN1,RCAN3,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,DESI1,MEF2B,TNS1,SLC25A28,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,SFXN1,HLF,NCKAP1L,PLK2,RASGRF2,ENTPD7,CCDC181,B3GALT2,SPART,ZBED8,LZTS1,INPPL1,ALOX5AP,CELSR1,EHHADH,ZHX3,GABRB2,SCN8A,OPHN1,SLC25A27,GTF2IRD1,ISYNA1,DYNC1I1,ADSSL1,NIPSNAP3B,CHD5,RPL13A,MYORG,MECOM,MCOLN2,GBGT1,NAV1,PDZD7,PIK3AP1,MSMO1,PRELID1,RUNDC3B,MPDZ,RIMS2,RNF152,EPB41L5,QSOX1,PLEKHA8,COL4A4,TCF24,COLGALT2,RABAC1,PLCB1,C4orf19,FAM162A,ZNF558,VPS37D,PMEPA1,PKN3,IQSEC2,AMPD1,ACSM3,PLA2G4A,FRMPD3,EPHA3,AMOTL1,PCSK1N,RASAL2,ELOVL4,RNF144A,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,TBC1D30,TMEM53,ZNF827,STARD4,NBEA,SCRN1,DAB2IP,NAP1L3,MARCKS,SERPINH1,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,TBC1D16,ZNF396,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,MAPK10,CTTNBP2,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,MXI1,ANKRD13D,GLIPR1L1,CLBA1,ATP9A,CCNJL,ARL2,RGS7,SELENOP,GDPD5,SLC35G2,NEDD4,HOPX,KDM7A,RGS17,SOAT2,MGAT1,SGK3,RALGAPA2,PRKG2,PHYKPL,FIG4,YBX3,SEPT3,GFI1,SPRY2,PFKFB4,SYNPO2,ARAP2,HYKK,MPP1,CTTNBP2NL,GUCY1A2,ZNF714,SKAP1,ZIC1,GPLD1,CEBPB,FGR,PCGF2,PGM2L1,TUFT1,MYOM2,B4GALT7,OCLN,ATP1A3,NUDT17,EXPH5,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,ABAT,CACNB4,RBM11,DNER,ABHD4,IKZF2,CEP85L,QPRT,FKBP11,CYP51A1,ARHGEF10L,RTN1,TUBB4A,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,SLC2A12,HRK,EPHB6,PTPRE,GALNT18,FANK1,SLIT2,RASGRP1,PRKACB,ATL1,CAPN5,ZNF565,ROR1,RNF44,SERGEF,GRK3,EML1,AK1,NCAM2,NCOA7,C8orf88,APBA2,SLC9B1,BCL11B,UST,FN1,SEC24D,JDP2,RIMKLA,ELOVL7,YPEL2,CYP4V2,ATP6V1E2,GALNT13,SATB1,PHGDH,DDIT4,CA2,RPS11,EBF4,NCEH1,MORN4,BARX1,NOS3,RAX,IL17RD,MSTN,SH2D2A,PARD3B,EDEM3,WWC1,DUSP9,GALNT17,PRDM1,LHPP,B4GALNT3,AMDHD1,GLCE,FCHO2,RAI14,HK2,DIRC2,CREB3L2,EML5,ZSWIM5,NEK10,IL15,PLEKHA5,MORC4,TDRKH,BCL6B,LACC1,UBTD2,DOCK2,SP8,ZSCAN5A,COL22A1,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,POU2F2,MET,ZNF460,HSPA2,GCA,PHLDB2,FER,TES,SYNJ2BP,DOCK5,TTLL7,C1orf174,WARS,TPK1,MSC,LMLN,BACH2,FAAP20,SOHLH2,CYP2U1,PSPH,TNIK,PRSS16,CLGN,REL,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,EHD3,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,OGDHL,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,MAP1B,RERE,GPR37,MYADM,NACC2,GCSAM,MPP7,PRCP,MAP2K6,SLC7A5,KIAA0513,KIF21A,GEM,MAP3K20,MMP16,STOM,SNPH |
| 6.315e-03 | -5.06 | V$CEBP_Q3 | MSigDB lists | V$CEBP_Q3 | 239 | 36 | 17377 | 1707 |
BCL11B,PLA2G4A,MXI1,DYRK3,NSUN6,CADM2,OVOL2,TRPS1,FOXP2,PPM1E,BCL6,NCAM1,FIGN,DOCK8,PDGFRB,MN1,NDUFA4L2,BDNF,MEIS2,CD55,PLS1,ATOH1,PALLD,GPLD1,BCL11A,ID3,KPNA3,MAP2K6,GNAO1,SFMBT1,MAOA,ZBTB20,DLG2,MID1,DDIT3,RAB30 |
| 6.315e-03 | -5.06 | V$E47_01 | MSigDB lists | V$E47_01 | 239 | 36 | 17377 | 1707 |
BCL11B,SCN5A,NBL1,SORBS1,ID1,KLHL13,ITGA6,OTX1,GABRG2,SORBS3,CHD5,CYP26A1,NUMBL,KCNJ4,MAP1A,MGAT1,STC2,CHRDL1,RAB26,MPPED2,CNNM2,EPHB6,PPP2R2B,TSHR,DPYSL5,NDUFA4L2,DUSP9,AIG1,PLCB1,KHDRBS2,SERGEF,GPR37,NSD1,ERN1,CDH2,FRMD5 |
| 6.315e-03 | -5.06 | V$DR4_Q2 | MSigDB lists | V$DR4_Q2 | 239 | 36 | 17377 | 1707 |
MPZL3,PCSK1N,LPAR2,ENO2,PLAG1,RASL11B,CTBP2,ZIC2,NOVA1,PRRG4,FOXP2,NELL2,PIK3AP1,SGK1,FAM155B,ERRFI1,LRP3,SEMA6C,ZNF385A,GLI1,PODXL2,MEIS2,RNF145,COL4A3,RAB6B,COL4A4,STRADB,OBSCN,ATP1B1,PLEKHA1,KCND3,PTK7,NXPH4,DLG2,ZBTB20,ABCG1 |
| 6.343e-03 | -5.06 | GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE | 143 | 24 | 17377 | 1707 |
DUSP8,PTPN6,DUSP9,NDRG2,ATF3,SYNJ2BP,MECOM,PTPRJ,IGF1R,GBP1,DACT1,CNKSR3,MYC,C1QL4,PRKCD,DUSP19,DAB2IP,SPRY4,BMP4,ERRFI1,TLR4,SPRY2,DUSP1,HMGCR |
| 6.347e-03 | -5.06 | VERHAAK_GLIOBLASTOMA_NEURAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_NEURAL | 120 | 21 | 17377 | 1707 |
UGT8,UROS,GABRB2,MGST3,NDRG2,DYNC1I1,HPCAL4,GNAI1,TTC1,CHN1,EPB41L3,POPDC3,SH3GL2,FUT9,PPFIA2,SGK3,ATRNL1,SERPINI1,FHIT,CRYL1,PGBD5 |
| 6.365e-03 | -5.06 | RNA polymerase II proximal promoter sequence-specific DNA binding | molecular function | GO:0000978 | 437 | 59 | 17224 | 1680 |
CREB3L2,BCL11B,KLF8,RUNX2,ZNF395,PLAG1,JDP2,OTX1,GATA3,STAT5B,CEBPA,ZNF219,NKX6-1,FOXP2,GRHL1,GATA2,MYC,SREBF1,TFAP2A,POU2F2,SMAD6,ETV1,CEBPD,GLI1,RAX,KCNIP3,ATF4,MEIS2,HNF4G,NR6A1,SOX21,NKX3-2,NR4A1,NFIA,LITAF,YAP1,MAFB,MEF2B,SATB2,ATF3,PRDM1,ATOH1,BATF,ZIC1,BATF3,BCL11A,CEBPB,SMAD3,NSD1,NACC2,CIART,KLF5,HOXD13,NKX2-8,NEUROG2,SMYD3,SIX2,DDIT3,MEF2C |
| 6.366e-03 | -5.06 | RYK (receptor-like tyrosine kinase) | protein interactions | 6259 | 88 | 17 | 17029 | 1718 |
WASF3,CELSR1,CELSR3,FZD8,CD276,DCHS1,NPM1,VIM,PCDH7,FAT4,NCR3LG1,PTK7,DSG2,PTPRS,CNNM2,ADGRA3,CDH2 |
| 6.393e-03 | -5.05 | GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | 42 | 10 | 17377 | 1707 |
GSN,MYADM,PRKCD,EPS8,ADD2,TMOD2,PFN2,SLIT2,FHOD3,SCIN |
| 6.393e-03 | -5.05 | KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | MSigDB lists | KUNINGER_IGF1_VS_PDGFB_TARGETS_DN | 42 | 10 | 17377 | 1707 |
FBXO32,EPS8,PRKG2,NCEH1,ERRFI1,ATP1A3,STOM,F3,CD53,CRYL1 |
| 6.398e-03 | -5.05 | negative regulation of programmed cell death | biological process | GO:0043069 | 928 | 112 | 17256 | 1658 |
EPHA3,PRKN,BTC,ID1,ACVR1,GRIK2,DNAJC3,LILRB1,GATA3,NPM1,STAT5B,NTRK3,PRKCA,DDR1,AARS,EYA4,TXNDC5,BAG3,ASNS,MAGEA3,BCL6,CTTN,EPHB6,MET,FANK1,ENO1,POU3F3,DOCK8,SNAI2,PDGFRB,LAMP3,CTH,PRAME,NKX3-2,LRRK2,BNIP3L,YAP1,AGO4,PRKCQ,WNT11,ROR1,ATOH1,FGFR1,SNCA,IRS2,SMAD3,BEX3,SH3RF1,NCKAP1L,PLK2,WFS1,MAP3K21,HGF,ERCC5,ATG5,NRP1,PPARGC1A,UNC5B,RETREG1,MEF2C,BCL11B,PRKAA2,TYRO3,DYRK3,LGALS3,PAK5,GABRB2,ITGA6,DHCR24,SLC25A27,GAS6,TNFRSF10C,EPHB1,MECOM,SYCP2,BNIP1,IGF1R,GATA2,MYC,PRKCD,PRELID1,SGK3,TFAP2A,LRP6,BNIP3,YBX3,SMAD6,STXBP1,SPRY2,ZNF385A,NOS3,DUSP1,HMGCR,FGFR4,SLC40A1,BDNF,MSX1,NUGGC,NUAK2,FHL2,STRADB,AGAP2,MGMT,HERPUD1,DKK1,CEBPB,TERT,XBP1,PCGF2,BMP4,SFN,TPT1 |
| 6.436e-03 | -5.05 | HAX1 (HCLS1 associated protein X-1) | protein interactions | 10456 | 132 | 23 | 17029 | 1718 |
DPYSL5,TNK2,GPM6A,ABCC4,SCAMP1,HNF4G,RAB6B,ANK2,TES,PRKAR2B,STAT5B,SNCA,TUBB4A,RNF217,MAP2,GNAO1,KIAA0513,SVIL,CTTN,NCAM1,MAPK10,STXBP1,CNTN1 |
| 6.436e-03 | -5.05 | skin-upper_arm-malignant_melanoma | COSMIC cancer mutations | skin-upper_arm-malignant_melanoma | 560 | 73 | 17385 | 1698 |
EXPH5,DMXL2,MYCBP2,CACNG3,ATP8A1,PTPN21,ACTL8,ENAH,ITPR2,FSTL5,NELL2,PPM1E,CHRNA5,CNKSR3,MET,PTPRE,ZNF365,DNAH5,NTNG1,ALG10B,FER,PHLDB2,ATL1,MARK1,DCC,KCNH5,ALDH1L2,ADCY1,CR2,TNS1,ZNF569,ARMC4,IQCH,PTPRJ,PLK2,PTK7,PTPRS,PPARGC1A,STON2,SV2B,STXBP5L,ROBO2,PTPRD,HERC5,EPHB1,MECOM,FOXP2,ZNF354A,ABCA5,FUT9,PDE10A,KIAA0319,SLC16A9,LIMCH1,FIGN,AGL,PAK1,TMC7,CRIM1,COL4A4,PTPN13,PARD3B,ST6GALNAC3,PLCB1,PTPRC,TEX15,ADAMTS3,PLXDC2,LAPTM4B,PTPRN2,KIF21A,ATP2B4,ABCG1 |
| 6.443e-03 | -5.04 | PID_MYC_REPRESS_PATHWAY | MSigDB lists | PID_MYC_REPRESS_PATHWAY | 62 | 13 | 17377 | 1707 |
SMAD3,MYC,ITGA6,TMEM126A,NDRG2,CEBPA,SFXN3,TMEFF2,GFI1,PDGFRB,CEBPD,DDIT3,DKK1 |
| 6.443e-03 | -5.04 | GO_MODIFIED_AMINO_ACID_BINDING | MSigDB lists | GO_MODIFIED_AMINO_ACID_BINDING | 62 | 13 | 17377 | 1707 |
GSTM2,MARK1,FCHO2,GSTM4,OSBPL5,FASN,CBS,GSTM3,MARCKS,GAS6,PTGES,RASGRP1,SCIN |
| 6.461e-03 | -5.04 | WALLACE_PROSTATE_CANCER_RACE_DN | MSigDB lists | WALLACE_PROSTATE_CANCER_RACE_DN | 76 | 15 | 17377 | 1707 |
RTN1,CDR2L,TRIM2,MARK1,RHOD,PLOD2,PTK7,SRD5A3,ADRB1,PRKG2,LIMCH1,FRK,PCLO,OCLN,PKIA |
| 6.461e-03 | -5.04 | REACTOME_OPIOID_SIGNALLING | MSigDB lists | REACTOME_OPIOID_SIGNALLING | 76 | 15 | 17377 | 1707 |
PLA2G4A,GNG12,PDE1B,GNB4,GNAO1,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PDE4D,PRKCA,PLCB1,PRKACB,GNAI1 |
| 6.461e-03 | -5.04 | regulation of transporter activity | biological process | GO:0032409 | 253 | 37 | 17256 | 1658 |
CACNG3,HECW2,NDFIP2,CACNB4,NEDD4,NOS1AP,LRRC55,KCNAB1,TCAF2,SCN1B,CACNB2,PRKCD,EHD3,SGK3,SGK1,PDE4D,SYNGR3,HSPA2,ALG10B,GSTM2,ANK2,SHANK2,JPH1,FGF12,RYR2,GSTO1,CTTNBP2NL,ATP1B1,SGK2,SNCA,KCNG1,GEM,PPARGC1A,TESC,CACNA2D1,STOM,MEF2C |
| 6.471e-03 | -5.04 | cAMP binding | molecular function | GO:0030552 | 24 | 7 | 17224 | 1680 |
PRKAR2B,PDE4D,POPDC3,BVES,PDE10A,RAPGEF2,RAPGEF4 |
| 6.476e-03 | -5.04 | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | MSigDB lists | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | 223 | 34 | 17377 | 1707 |
NBL1,RUNX2,BMPR2,GATA3,RASL11B,DOK5,NEDD4,MECOM,NEO1,SKI,TGFBR3,ITGB3,CHRDL1,ACVR2A,DAB2IP,SMAD6,SLIT2,SPRY2,PCSK6,FZD1,NKX2-1,VEGFC,MSX1,FZD4,FGFR1,DKK1,SMAD3,FBN1,ADAMTS3,PMEPA1,PRKCB,CCBE1,GRB10,BMP4 |
| 6.489e-03 | -5.04 | MORF_ATF2 | MSigDB lists | MORF_ATF2 | 306 | 44 | 17377 | 1707 |
TNIK,RUNX2,EHHADH,CFH,GABRB2,LRP4,RNF24,IL13RA1,RGS7,FAM13A,PRKCA,TPD52L1,COL14A1,FAM110B,SEMA6A,GPR15,PPM1E,SOAT2,FRY,TACC2,PDE10A,COL19A1,PDE4D,ST8SIA1,MYT1,NEB,B4GALT6,GCA,WISP3,KLHL23,CDC42BPA,SLC46A3,GPR19,PLEKHB1,ZNF266,ADAMTS3,MAP2,ITGBL1,MAP2K6,PTPRS,TANC2,NR3C2,SMYD3,CACNA2D1 |
| 6.512e-03 | -5.03 | positive regulation of ossification | biological process | GO:0045778 | 85 | 16 | 17256 | 1658 |
PDLIM7,RUNX2,ACVR1,BMPR2,ZHX3,CEBPA,ACVR2B,BMP6,SMAD3,CEBPB,TFAP2A,ACVR2A,HGF,BMP4,BMPR1A,MEF2C |
| 6.519e-03 | -5.03 | synaptic vesicle | cellular component | GO:0008021 | 173 | 27 | 18223 | 1724 |
DOC2A,DMXL2,SV2B,SLC40A1,BDNF,RAB3B,SCAMP1,SYT12,VAMP8,LRRK2,SNAP25,RABAC1,APBA1,SNCA,TRIM9,ICA1,UNC13B,RAB26,PTPRS,PTPRN2,SEPT5,SYNGR3,RAB27B,APBA2,CTTNBP2,STON2,MME |
| 6.520e-03 | -5.03 | central_nervous_system-spinal_cord-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-spinal_cord-glioma-astrocytoma_Grade_IV | 24 | 7 | 17385 | 1698 |
QSOX1,TNFSF4,TERT,DNAH6,FGFR1,MATN2,FHDC1 |
| 6.528e-03 | -5.03 | V$AP1_Q4 | MSigDB lists | V$AP1_Q4 | 256 | 38 | 17377 | 1707 |
PLBD2,IGFBP6,ASS1,STAT5B,ABHD4,COL27A1,ATXN7L1,ZNF362,TECPR1,MAP1A,SCRN1,BNIP3,PDE4D,PDGFRB,GAB2,GAPDH,USP2,DSTN,DCHS1,FGF12,VIM,PRDM1,ARRDC4,UCHL3,ZIC1,ISG20,GPR150,GNAI1,GSN,MAP2,PKN3,AKT3,ABI3,HS3ST3B1,PAX9,LIFR,SFN,LPP |
| 6.528e-03 | -5.03 | V$NFE2_01 | MSigDB lists | V$NFE2_01 | 256 | 38 | 17377 | 1707 |
DOC2A,NUDT10,SV2B,PLBD2,PDE1B,GCAT,ASS1,ABHD4,SEL1L3,PRR7,PHLDA2,SPEG,CHN2,MAP1A,SLC22A18,SCRN1,BNIP3,FHIT,SNX10,ENO1,GAB2,ATL1,BCL7A,GAPDH,ESRRG,FGF12,PRDM1,TTLL7,TTC28,METAP1D,GABARAPL1,MAP2,PKN3,AKT3,ALDOA,HS3ST3B1,MAPK10,COBL |
| 6.529e-03 | -5.03 | synaptic vesicle recycling | biological process | GO:0036465 | 43 | 10 | 17256 | 1658 |
DNM3,SH3GL2,FCHO2,DNAJC6,OPHN1,NLGN4X,PACSIN1,CANX,STON2,SNCA |
| 6.529e-03 | -5.03 | response to epidermal growth factor | biological process | GO:0070849 | 43 | 10 | 17256 | 1658 |
ID1,PDE8A,MARS,STAT5B,GAREM1,DAB2IP,ERRFI1,ZFP36L2,BAIAP2,SNAI2 |
| 6.548e-03 | -5.03 | GO_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | MSigDB lists | GO_PHOSPHORIC_ESTER_HYDROLASE_ACTIVITY | 340 | 48 | 17377 | 1707 |
INPPL1,DUSP8,PDE1B,PTPRD,UBASH3B,PTPN21,NOTUM,LPIN3,GDPD5,INPP1,PGAP1,EYA4,PPM1E,CDC14B,PDE10A,FIG4,PDE4D,PTPRE,SMPDL3A,CHRM3,DUSP1,PFKFB4,SSH3,PPP1R3D,PFKFB2,PTPRU,PTPN13,PTPN6,DNAJC6,GDPD1,DUSP9,PDE8A,LHPP,PLCB1,SMPDL3B,NT5DC2,GPLD1,PTPRC,ENPP1,PTPRJ,ENPP6,DUSP19,INPP4B,PTPRN2,PTPRS,INPP5F,PLD1,PSPH |
| 6.555e-03 | -5.03 | GOLDRATH_HOMEOSTATIC_PROLIFERATION | MSigDB lists | GOLDRATH_HOMEOSTATIC_PROLIFERATION | 159 | 26 | 17377 | 1707 |
CD55,GSTM2,RECK,NPM3,KCTD12,IGF2BP2,SCD,ATP11A,PLEKHA1,NHP2,PRKCA,CANX,SNX9,FAM162A,RNF141,SFXN1,ZFP62,SEMA4F,EOMES,NACC2,SLC7A5,PCGF2,DUSP19,KLF9,MYO6,CTNND2 |
| 6.555e-03 | -5.03 | MTOR_UP.V1_UP | MSigDB lists | MTOR_UP.V1_UP | 159 | 26 | 17377 | 1707 |
PDK1,LGALS3,DHCR24,LDLR,GABRG2,AK4,ATF3,ISYNA1,PRKCA,STEAP1,CYP26A1,CYP51A1,ATXN7L1,TMEM53,HMGCS1,IDI1,BACH2,MSMO1,ALDOC,STARD4,ERN1,CDH17,SQLE,DHCR7,ZNF518B,TESC |
| 6.616e-03 | -5.02 | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP | MSigDB lists | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP | 167 | 27 | 17377 | 1707 |
ARHGAP26,KCNIP3,RUNX2,TTC39B,PTPN13,HIP1,COBLL1,PRDM1,CHSY1,IL18R1,SMPDL3B,HOPX,GABARAPL1,GALNT3,BAG3,PTPRJ,MYADM,PMAIP1,GPR160,RAP2A,FAM107B,GTF2F2,GEM,ATG5,SNX10,ATP2B4,PERP |
| 6.616e-03 | -5.02 | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | 167 | 27 | 17377 | 1707 |
SYNPO2,SLC3A2,SESN2,DYRK3,LRRC8B,NR4A1,RAPGEF2,FERMT2,HECW2,PHACTR2,CHAC1,SAV1,SNX9,ASPH,SLC19A2,PHLDA2,DDIT4,PMAIP1,CSF1,STARD4,SGK1,TNFSF15,PLD1,GEM,ERRFI1,SPRY2,DUSP1 |
| 6.617e-03 | -5.02 | NAAA (N-acylethanolamine acid amidase) | protein interactions | 27163 | 54 | 12 | 17029 | 1718 |
MAN2B2,TUBA1A,TCTN2,CEMIP2,CNTNAP3,SEC24D,UGDH,NXPH4,PLTP,CLN5,PCSK5,DCBLD2 |
| 6.617e-03 | -5.02 | SIAE (sialic acid acetylesterase) | protein interactions | 54414 | 54 | 12 | 17029 | 1718 |
CHSY3,MAN2B2,TGFBR3,CEMIP2,CNTNAP3,COL18A1,MOXD1,PLTP,CPE,FAM162A,MYORG,DCBLD2 |
| 6.619e-03 | -5.02 | ADF-H/Gelsolin-like_dom_sf | interpro domains | IPR029006 | 24 | 7 | 18492 | 1811 |
SVIL,DBN1,GSN,COTL1,SEC24D,DSTN,SCIN |
| 6.619e-03 | -5.02 | RALGPS2 (Ral GEF with PH domain and SH3 binding motif 2) | protein interactions | 55103 | 35 | 9 | 17029 | 1718 |
CGN,RASAL2,PTPN13,MAP3K21,CBY1,TANC2,LPIN3,OSBPL6,SFN |
| 6.625e-03 | -5.02 | parathyroid-adenoma | COSMIC cancer mutations | parathyroid-adenoma | 192 | 30 | 17385 | 1698 |
GPM6A,SH3BP2,B3GALT1,LANCL3,PTPN21,KIF5C,PRRG1,ZFYVE9,ZNF569,ZNF354A,POU5F1B,FAT1,PRKCD,LAMB1,B3GALT2,NXPH4,GRIP1,HGF,LIMCH1,ERCC5,DYNC2H1,TLN2,UNC5B,PTPRE,DNAH5,MMP16,NEB,ATP2B1,ACSM3,TBC1D8 |
| 6.631e-03 | -5.02 | cellular response to nitrogen compound | biological process | GO:1901699 | 588 | 75 | 17256 | 1658 |
PRKN,SORBS1,ID1,ASS1,NPM1,STAT5B,ITPR2,TLR3,PDE4D,TLR4,TSHR,SLIT2,PRKACB,FER,SESN2,ATF4,UROS,LRRK2,ADCY1,PRKAR2B,AGO4,SESN1,SNCA,SMAD3,IRS2,ENPP1,EIF4EBP1,GNB4,RGS10,MAPK13,KLF5,PPARGC1A,RRAGD,MEF2C,GNG12,GABRB2,IPO5,ATP6V1E2,GABRG2,NKX6-1,IGF1R,CA2,PRKCD,GHR,SREBF1,ADCY6,ERRFI1,PCK2,CHRM3,TRPM4,PAK1,GSTM2,PXN,RHOQ,NR4A1,RAPGEF2,RYR2,MARS,PLCB1,TLR6,CPEB1,BAIAP2,GPLD1,CEBPB,TRIB3,TERT,FBN1,XBP1,RAB31,SH3BP4,TBC1D4,LARP1,ATP2B4,CACNA2D1,ATP1A3 |
| 6.642e-03 | -5.01 | presynaptic membrane | cellular component | GO:0042734 | 79 | 15 | 18223 | 1724 |
GRIK4,UNC13B,FCHO2,GRIK2,APBB1,ADGRL1,HIP1,KCTD12,CADPS2,SNAP25,NRXN1,STXBP1,CDH2,RIMS2,SNPH |
| 6.653e-03 | -5.01 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_UP | 175 | 28 | 17377 | 1707 |
GPR176,TRIM2,MARK1,ADAL,PDK1,PFKFB2,SYT12,GJB2,WLS,FHDC1,PLXNA2,ACO1,TDRKH,PDE8A,ARHGAP32,TRIM9,EBF1,GAS2L3,PRELID2,MAOA,NAP1L3,DISP1,RNF130,NRP1,NCAM1,JAM2,PCSK6,CRYL1 |
| 6.653e-03 | -5.01 | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_UP | 175 | 28 | 17377 | 1707 |
EXPH5,MEIS2,SH3BP2,ZNF395,MSTN,TES,PTPN21,KCND3,ZFPM2,SKAP1,SATB1,BAIAP2,RPL34,GJC1,EPB41L3,SYCP2,IFT81,IQCH,HMGCS1,BACH2,PLK2,BCL6,NXPH4,MAPK13,KLHL29,MLLT3,SNAI2,TPT1 |
| 6.653e-03 | -5.01 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_UP | 175 | 28 | 17377 | 1707 |
PPP1R3D,MYLK3,SEC24D,XYLT1,RPL21,VLDLR,CR2,HBE1,P2RY1,TTC28,CHD5,JAM3,NT5DC2,NEDD4,GPR37,TMCO3,PLOD2,ENTPD7,PLK2,TNFRSF1A,SH3BP4,HPGD,TMED9,KLHL29,PTPRE,PRR16,RPS23,CEBPD |
| 6.657e-03 | -5.01 | Ion_trans | pfam domains | PF00520 | 106 | 19 | 17054 | 1666 |
KCNV1,TRPM4,SCN5A,KCNQ3,SLC9C1,CACNA1E,KCNH5,SCN8A,RYR2,ITPR2,KCND3,KCNC4,KCNG1,KCNS3,TRPC1,SCN2A,TRPC3,SCN3A,KCNB2 |
| 6.660e-03 | -5.01 | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | 191 | 30 | 17377 | 1707 |
MYO1D,MPP1,BLVRB,RNF24,PKN1,C4orf19,KCNC4,ARHGEF26,CYP26A1,MAGI3,C9orf116,F3,IRS2,DOCK7,LMLN,MYADM,MSMO1,MPP7,MCF2L,PRKCD,TMEM86A,CCDC146,SGK3,GRB10,SLC22A15,BMPR1A,TLR4,SNX10,CHRM3,MEF2C |
| 6.660e-03 | -5.01 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_UP | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_UP | 191 | 30 | 17377 | 1707 |
PDLIM7,SLC3A2,DNM3,MEIS2,SEC24D,NR4A1,REL,PTPN21,TMTC4,CLSTN2,SEZ6L2,TCERG1L,MLC1,KREMEN1,STEAP1,NCS1,DDIT4,CEBPB,SLC39A14,KIAA0895,SLC7A11,FBN1,SH3RF1,MGAT1,LRRIQ3,SGK1,SLC22A15,SERPINH1,DCBLD1,ATP1A3 |
| 6.660e-03 | -5.01 | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | MSigDB lists | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | 191 | 30 | 17377 | 1707 |
DOC2A,PDLIM7,RUNX2,CACNG3,TBC1D1,WLS,MPP1,LRRK2,NFIA,SLC25A28,RAB38,SAV1,MLC1,DOCK2,CPEB1,PCDH7,WARS,NAP1L5,DEXI,FKBP9,TLR3,GYPC,CSF1,SREBF1,RRAS2,MLLT3,BTRC,SMPDL3A,B4GALT6,PARP9 |
| 6.661e-03 | -5.01 | glutamate receptor binding | molecular function | GO:0035254 | 30 | 8 | 17224 | 1680 |
NECAB2,AKAP5,SHANK2,HOMER2,HIP1,DLG2,CANX,HOMER3 |
| 6.666e-03 | -5.01 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_UP | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_UP | 183 | 29 | 17377 | 1707 |
SUSD3,INPPL1,FARP1,PRSS12,PLEKHA8,HEBP1,TNFSF13B,PRDM1,OVOL2,NPC2,APBA1,BEX2,CRYBG3,SMPDL3B,HOPX,CAMK2N1,SLC22A17,CHRNA5,CFHR1,PRKG1,BDH2,SMTN,TFAP2A,MYO6,GLIS1,CTTNBP2,OSBPL6,SYK,CRISPLD1 |
| 6.666e-03 | -5.01 | GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_UP | MSigDB lists | GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_UP | 183 | 29 | 17377 | 1707 |
RWDD2A,MAN2B2,INPPL1,CD276,DEPTOR,SPATA13,DDR1,C1orf174,FGFR1,CYP26A1,BAIAP2,BEX4,RTN1,IFT81,FBXO32,RPS6KA2,GPRC5B,ABCA5,FAT1,MAP2K6,PEMT,ERN1,DYNC2LI1,ZNF704,FBRSL1,ALPK1,CTNND2,FES,GLI1 |
| 6.666e-03 | -5.01 | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP | MSigDB lists | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP | 183 | 29 | 17377 | 1707 |
CREB3L2,RHOQ,PAGE1,ENO2,RHOBTB1,TGFA,PPFIBP2,LMCD1,COTL1,GRK6,PALLD,PRKCA,DKK1,IFT81,SLC7A11,PDZD8,NACC2,PDE10A,TSC22D1,SQLE,SGK1,GRB10,MARCKS,PAX9,OXTR,TMEM120B,SPRY2,ATP2B1,GLDC |
| 6.666e-03 | -5.01 | RPS14_DN.V1_UP | MSigDB lists | RPS14_DN.V1_UP | 183 | 29 | 17377 | 1707 |
DMXL2,RIN2,RASAL2,FLVCR2,SH2D2A,CRIM1,KCTD12,ADAMTS6,TNFRSF10C,SFXN3,SESN1,CACNB4,KBTBD11,SMAD3,FRY,KMO,PLK2,CCNA1,BCL6,RAB31,ACTA2,MARCKS,PDE4D,GFI1,PTPRE,IL1RAP,SCN3A,CYP1B1,HEY1 |
| 6.666e-03 | -5.01 | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_UP | 183 | 29 | 17377 | 1707 |
LATS2,FER,PHLDB2,ANKRD13D,CFH,BTNL9,NR4A1,DSTN,BACE1,MCTP2,TNFSF13B,MAPK4,GAS6,TNKS1BP1,TIAM2,MCU,SMAD3,PTPRC,TEX15,KIAA0895,SEMA4F,PLAGL1,ABI3BP,PDE4D,NCAM1,FAR2,PLTP,PURG,DUSP1 |
| 6.666e-03 | -5.01 | GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP | 183 | 29 | 17377 | 1707 |
TTC39B,WLS,SPATA13,MRPL22,HERC6,INPP1,SCIN,HEG1,ISG20,CXCL10,RSL24D1,TLR3,IDI1,SETDB2,GYPC,INSIG1,TRIM34,PMEPA1,EHD3,STARD4,NCOA7,INPP4B,SQLE,NCEH1,CMPK2,SLFN5,LARP1,MED12L,PARP9 |
| 6.666e-03 | -5.01 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_UP | 183 | 29 | 17377 | 1707 |
COL9A3,ENO2,PNRC1,IL15,REL,RAPGEF2,STAT4,RAPGEF4,FERMT2,AK4,COL4A5,SNAP25,FAM131B,ISG20,TRIM9,TUBB4A,GBP1,AFF2,PLK2,BNIP3,HGF,GFI1,MAGI2,ENO1,COL9A2,LAMP3,GLDC,DUSP1,IGFBP3 |
| 6.667e-03 | -5.01 | GRM1 (glutamate metabotropic receptor 1) | protein interactions | 2911 | 18 | 6 | 17029 | 1718 |
EFNB2,TRPC1,GAPDH,PRKCA,SYK,HOMER2 |
| 6.667e-03 | -5.01 | COLQ (collagen like tail subunit of asymmetric acetylcholinesterase) | protein interactions | 8292 | 18 | 6 | 17029 | 1718 |
COLGALT2,P4HA1,TEX15,FN1,BCHE,PLOD2 |
| 6.667e-03 | -5.01 | CRLF3 (cytokine receptor like factor 3) | protein interactions | 51379 | 18 | 6 | 17029 | 1718 |
MOB1B,DOCK7,ENPP6,ZBED8,DOCK6,DOCK8 |
| 6.667e-03 | -5.01 | CD22 (CD22 molecule) | protein interactions | 933 | 18 | 6 | 17029 | 1718 |
PTPRC,LCP2,SYK,PTPN6,ST6GAL1,ATP2B4 |
| 6.686e-03 | -5.01 | MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3) | protein interactions | 8491 | 13 | 5 | 17029 | 1718 |
IL13RA1,SORBS1,SH3GL2,SH3RF1,GAN |
| 6.686e-03 | -5.01 | BDKRB2 (bradykinin receptor B2) | protein interactions | 624 | 13 | 5 | 17029 | 1718 |
BAG3,GRK6,GRK3,PRKCD,NOS3 |
| 6.699e-03 | -5.01 | LDLRECEPTOR | prints domains | PR00261 | 24 | 7 | 4652 | 458 |
LRP6,ST14,LRP3,LRP4,VLDLR,LDLR,LRP12 |
| 6.708e-03 | -5.00 | epithelial cell differentiation | biological process | GO:0030855 | 652 | 82 | 17256 | 1658 |
EXPH5,TFCP2L1,ACVR1,ID1,ST14,ACTL8,MCOLN3,GATA3,PKP2,COL18A1,NTRK3,DLX6,MARVELD2,KAZN,ALDOC,RAP2A,POF1B,GSTM3,PDE4D,MET,PERP,GLI1,NKX2-1,FZD1,INTU,NKX3-2,YAP1,WNT11,VIM,ACVR2B,ATOH1,SAV1,DSP,ARHGEF26,FGFR1,SMAD3,PTK7,ITGA2,BDH2,PTPRS,KLF5,NRP1,MAGI2,MEF2C,HEY1,BCL11B,LGALS3,BMPR2,OPHN1,TJP1,OVOL2,SPINK5,BMP6,NKX6-1,SLC7A11,PDZD7,DSG2,ACTA2,PCK2,BARX1,PCSK6,EPB41L5,PTCH2,B9D1,ENAM,KDM5B,RAPGEF2,PRDM1,PALLD,FNDC3A,MGMT,HEG1,CEBPB,ID3,MYADM,CTSV,XBP1,BMP4,CDH2,FOXA1,SFN,SIX2 |
| 6.723e-03 | -5.00 | Sema | pfam domains | PF01403 | 30 | 8 | 17054 | 1666 |
SEMA6B,SEMA3C,MET,SEMA4F,SEMA3A,SEMA6A,SEMA6C,PLXNA2 |
| 6.723e-03 | -5.00 | GPS | pfam domains | PF01825 | 30 | 8 | 17054 | 1666 |
ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRG6,ADGRL2,ADGRB2,ADGRL1 |
| 6.727e-03 | -5.00 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_DN | 24 | 7 | 17377 | 1707 |
MAFB,SAMD13,FRY,RHOBTB1,KLHL3,VGLL4,SESN1 |
| 6.727e-03 | -5.00 | GO_NUCLEOTIDE_KINASE_ACTIVITY | MSigDB lists | GO_NUCLEOTIDE_KINASE_ACTIVITY | 24 | 7 | 17377 | 1707 |
AK4,AK1,DLG2,CMPK2,MPP1,MAGI3,MPP2 |
| 6.727e-03 | -5.00 | JACKSON_DNMT1_TARGETS_DN | MSigDB lists | JACKSON_DNMT1_TARGETS_DN | 24 | 7 | 17377 | 1707 |
GRB10,SCD,COL6A2,HPS1,GJB2,FZD8,LDLR |
| 6.727e-03 | -5.00 | GO_POSITIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY | 24 | 7 | 17377 | 1707 |
INTU,CHSY1,DYNC2H1,DISP1,SHOX2,FOXA1,GLI1 |
| 6.765e-03 | -5.00 | odontogenesis of dentin-containing tooth | biological process | GO:0042475 | 78 | 15 | 17256 | 1658 |
BCL11B,ENAM,SCN5A,MSX1,RUNX2,CA2,EDA,ITGA6,LRP4,LRP6,ACVR2B,DLX2,BMP4,BMPR1A,PERP |
| 6.781e-03 | -4.99 | HUANG_FOXA2_TARGETS_DN | MSigDB lists | HUANG_FOXA2_TARGETS_DN | 36 | 9 | 17377 | 1707 |
IGFBP6,GALNT6,ST6GAL1,CRIP2,STEAP3,PROS1,SMAD6,LEPR,ATP2B4 |
| 6.781e-03 | -4.99 | GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | MSigDB lists | GO_ACTIN_POLYMERIZATION_OR_DEPOLYMERIZATION | 36 | 9 | 17377 | 1707 |
WASF3,MICAL2,GSN,EVL,DSTN,PREX1,COBLL1,CTTN,COBL |
| 6.781e-03 | -4.99 | GO_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY | MSigDB lists | GO_SEMAPHORIN_PLEXIN_SIGNALING_PATHWAY | 36 | 9 | 17377 | 1707 |
SEMA6B,SEMA4F,PLXNA2,SEMA3C,MET,NRP1,SEMA3A,SEMA6A,SEMA6C |
| 6.785e-03 | -4.99 | HSP90AA1 (heat shock protein 90 alpha family class A member 1) | protein interactions | 3320 | 806 | 103 | 17029 | 1718 |
PRKN,TRIM2,NPM1,COBLL1,C20orf194,CHUK,MAPK4,NTRK3,GRK6,CANX,PRKCA,DDR1,AARS,TXNDC5,BAG3,TYMP,RPS6KA2,DLX6,RPS6KL1,MYO3B,BCL6,KCNS3,MARCKS,EPHB6,MET,KLHL29,HSPA2,PRKACB,PDGFRB,TNK2,FER,GAPDH,MYLK3,TUBA1A,ACVR1C,KLHL23,LRRK2,AGO4,PRKCQ,ATF3,ACVR2B,SGK2,FRK,FGFR1,SNCA,DYRK1B,PRKCB,ALDOA,ERN1,KCNG1,TNFRSF1A,ZBTB20,BMPR1A,NR3C2,MID1,RPS20,PRKAA2,TYRO3,FN1,RHOBTB1,KLHL13,FBXO4,UBASH3B,TJP1,ZNF215,PKN1,HERC6,RGS7,EPHB1,HOPX,TTC1,FOXP2,IGF1R,EEF2,MYC,PRKCD,SREBF1,SGK3,GAN,PRKG2,SGK1,ALPK1,FBXL2,FES,NOS3,PAK1,FASN,NUAK2,PRDM1,GUCY1A2,FAM162A,MGMT,MKX,SUGT1,FGR,TERT,AKT3,HK2,SVIL,NEK11,FBXO27,SMYD3,BTRC |
| 6.820e-03 | -4.99 | human chr4q28.3 | chromosome location | human chr4q28.3 | 11 | 4 | 26185 | 1967 |
PCDH18,PCDH10,SLC7A11,SLC7A11-AS1 |
| 6.820e-03 | -4.99 | human chr3q25.2 | chromosome location | human chr3q25.2 | 11 | 4 | 26185 | 1967 |
P2RY1,ARHGEF26-AS1,ARHGEF26,MME |
| 6.820e-03 | -4.99 | human chr4q21.23 | chromosome location | human chr4q21.23 | 11 | 4 | 26185 | 1967 |
NKX6-1,HPSE,WDFY3-AS2,CDS1 |
| 6.845e-03 | -4.98 | V$NFAT_Q6 | MSigDB lists | V$NFAT_Q6 | 232 | 35 | 17377 | 1707 |
CXCR5,ACVR1,JDP2,VAMP8,NDRG2,NOTUM,CREB5,P2RY1,IKZF2,SPINK5,PRRG4,TRPS1,FOXP2,ZNF362,TACC2,COL25A1,GHR,NBEA,MARCKS,PDE4D,POU3F3,IGFBP3,PCDH10,USP2,KLHL3,SOX21,ZIC1,ADAMTS17,SH3RF1,PLOD2,GNAO1,TNFRSF1A,INPP5F,SHOX2,NR3C2 |
| 6.845e-03 | -4.98 | Biosynthesis of amino acids | KEGG pathways | ko01230 | 74 | 15 | 7161 | 730 |
GPT2,GAPDH,ENO2,AADAT,ALDOC,ALDOA,ACO1,ASS1,CBS,ABHD14A-ACY1,PHGDH,ENO1,PSPH,CTH,PYCR1 |
| 6.845e-03 | -4.98 | Biosynthesis of amino acids | KEGG pathways | hsa01230 | 74 | 15 | 7161 | 730 |
GPT2,GAPDH,ENO2,AADAT,ALDOC,ALDOA,ACO1,ASS1,CBS,ABHD14A-ACY1,PHGDH,ENO1,PSPH,CTH,PYCR1 |
| 6.847e-03 | -4.98 | Ion_trans_dom | interpro domains | IPR005821 | 106 | 19 | 18492 | 1811 |
KCNV1,TRPM4,SCN5A,KCNQ3,SLC9C1,CACNA1E,SCN8A,KCNH5,RYR2,ITPR2,KCND3,KCNC4,KCNG1,KCNS3,TRPC1,SCN2A,TRPC3,KCNB2,SCN3A |
| 6.936e-03 | -4.97 | cortical cytoskeleton | cellular component | GO:0030863 | 102 | 18 | 18223 | 1724 |
DBN1,MPP1,CAP2,DSTN,HIP1,PLS1,PCLO,PPP1R9A,GSN,PLEKHH2,MYADM,GYPC,WIPF3,RTKN2,CTTN,CDH2,MYRIP,RIMS2 |
| 6.943e-03 | -4.97 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | MSigDB lists | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | 49 | 11 | 17377 | 1707 |
NMNAT3,MOCOS,ENPP1,GSTO2,PANK1,FASN,GSTO1,SLC19A2,PANK3,TPK1,QPRT |
| 6.943e-03 | -4.97 | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | MSigDB lists | REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS | 49 | 11 | 17377 | 1707 |
SLC7A1,SLC3A2,SLC7A11,SLC36A1,SLC7A5,SLC6A15,SLC7A2,SLC1A3,SLC1A5,SLC16A10,SLC43A1 |
| 6.943e-03 | -4.97 | chr6q21 | MSigDB lists | chr6q21 | 49 | 11 | 17377 | 1707 |
POPDC3,BVES,TUBE1,PRDM1,FIG4,MARCKS,ATG5,SESN1,FRK,SLC16A10,HACE1 |
| 6.943e-03 | -4.97 | CAGTCAC,MIR-134 | MSigDB lists | CAGTCAC,MIR-134 | 49 | 11 | 17377 | 1707 |
ZNF711,ACSL1,KPNA3,GNAO1,C1orf21,TSC22D1,PSD3,ZFPM2,SMAD6,VGLL4,ILDR2 |
| 6.950e-03 | -4.97 | inner ear morphogenesis | biological process | GO:0042472 | 93 | 17 | 17256 | 1658 |
CELSR1,OTX1,GATA3,MAFB,ATOH1,FOXG1,HOXA1,FGFR1,ZIC1,INSIG1,GATA2,PDZD7,PTK7,DLX6,MYO3B,TFAP2A,SPRY2 |
| 6.951e-03 | -4.97 | REACTOME_DAG_AND_IP3_SIGNALING | MSigDB lists | REACTOME_DAG_AND_IP3_SIGNALING | 30 | 8 | 17377 | 1707 |
PDE1B,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PRKCA,PRKACB |
| 6.951e-03 | -4.97 | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_DN | MSigDB lists | SEITZ_NEOPLASTIC_TRANSFORMATION_BY_8P_DELETION_DN | 30 | 8 | 17377 | 1707 |
FKBP9,LIMCH1,INSIG1,TGFA,SLC19A2,PSPH,DDIT4,FKBP11 |
| 6.951e-03 | -4.97 | chr13q34 | MSigDB lists | chr13q34 | 30 | 8 | 17377 | 1707 |
IRS2,ADPRHL1,RASA3,TMCO3,ATP11A,GAS6,MCF2L,RAP2A |
| 6.953e-03 | -4.97 | skeletal system morphogenesis | biological process | GO:0048705 | 204 | 31 | 17256 | 1658 |
MSX1,INPPL1,RUNX2,BMPR2,NKX3-2,FOXN3,ARID5B,SATB2,ACVR2B,CHSY1,PLEKHA1,BMP6,HOXA1,FGFR1,COL27A1,SKI,SMAD3,IRX5,INSIG1,WDR19,PCGF2,BMP1,TFAP2A,SH3PXD2B,DLX2,BMP4,SERPINH1,SHOX2,MMP16,SIX2,MEF2C |
| 6.954e-03 | -4.97 | TSP_1 | pfam domains | PF00090 | 56 | 12 | 17054 | 1666 |
ADAMTS17,UNC5C,ADGRB3,ADAMTS3,THSD4,ISM1,THSD7B,ADAMTS6,UNC5B,THSD1,HMCN1,ADGRB2 |
| 6.985e-03 | -4.96 | collagen binding | molecular function | GO:0005518 | 63 | 13 | 17224 | 1680 |
PAK1,SMAD3,MRC2,FN1,ABI3BP,CCBE1,ITGA2,CHADL,PCOLCE2,SERPINH1,DDR1,COL14A1,ADGRG6 |
| 6.985e-03 | -4.96 | Rac GTPase binding | molecular function | GO:0048365 | 63 | 13 | 17224 | 1680 |
PAK1,VAV3,DOCK7,FARP1,PAK5,EPS8,PREX1,SRGAP1,SPATA13,PKN1,DOCK2,ARHGAP44,HACE1 |
| 6.988e-03 | -4.96 | GO_APICAL_JUNCTION_COMPLEX | MSigDB lists | GO_APICAL_JUNCTION_COMPLEX | 121 | 21 | 17377 | 1707 |
CGN,AMOTL1,SORBS1,BVES,PARD3B,RAPGEF2,TJP1,JAM3,MAGI3,EPCAM,MPP7,ATP7B,MARVELD2,CLDN12,POF1B,LIN7A,MPDZ,MAGI2,JAM2,NPHP1,OCLN |
| 6.992e-03 | -4.96 | desmosome | cellular component | GO:0030057 | 25 | 7 | 18223 | 1724 |
POF1B,PKP2,DSP,JAM3,KAZN,PERP,DSG2 |
| 7.004e-03 | -4.96 | pelvis | COSMIC cancer mutations | pelvis | 1008 | 122 | 17385 | 1698 |
EPHA3,SORBS1,TRIM2,ELOVL4,CELSR3,ATP8A1,CCDC110,PSTPIP2,LILRB1,CHAC1,DOCK3,KIF21B,KIAA1217,SEZ6L2,RADIL,ZFYVE9,CCNJ,TRPS1,GPR15,RNF150,SEC16B,TACC2,ABI3BP,REEP1,ACVR2A,RTKN2,KIAA1614,MYH15,SLC2A12,FHIT,PCOLCE2,PROS1,PTPRE,DNAH5,TSHR,MYT1,NTNG1,DOCK8,PHLDB2,DCC,PTPN6,TES,ANK2,LRRK2,NFE2L1,CHRNA6,CR2,TNS1,ATP1B1,ACVR2B,INTS6,RNF44,SERGEF,ATP10D,BCL11A,SLC7A1,ZNF266,HPSE,PLK2,ALDOA,PIK3C2B,DSEL,PLD5,UNC5B,CTTNBP2,HEY1,SV2B,ANKRD13D,SLC6A9,WDR17,INPPL1,PTPRD,TSPAN15,ESRP1,NSUN6,OPHN1,GABRG2,SETBP1,LAMC3,PHGDH,COL27A1,NEDD4,HSPA12B,KIAA1958,CHN2,CA2,EEF2,MAP1A,BCHE,FRAS1,CACNB2,RUNDC3B,MYO6,FIGN,ATP2B1,CKAP4,CES3,HMGCR,PARD3B,VLDLR,ZNF605,KIAA1324L,RYR2,SDC3,FERMT2,OBSCN,SDK1,ZBBX,PALLD,ZFPM2,GUCY1A2,TEX15,MYADM,KIAA0355,CSF1,FAT1,THSD7B,HK2,PLD1,PTGES,NPHP1,ACSM3 |
| 7.014e-03 | -4.96 | V$CDPCR3HD_01 | MSigDB lists | V$CDPCR3HD_01 | 216 | 33 | 17377 | 1707 |
IL15,OTX1,CLSTN2,STAT5B,MGAT5B,IKZF2,NOVA1,PFN2,DACH2,EYA4,MECOM,ATXN7L1,ZNF827,ADCK1,LHX6,ACVR2A,MYT1,ETV1,C15orf41,KCNB2,DPP10,MN1,HNF4G,FOXN3,OBSCN,NEGR1,GRIK4,C1orf21,ALDOA,NXPH4,DLG2,SERPINI1,NR3C2 |
| 7.035e-03 | -4.96 | GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 152 | 25 | 17377 | 1707 |
TRPM4,GPM6A,CACNG3,CACNA1E,MCOLN3,RYR2,RASA3,ITPR2,GAS6,CACNB4,ASPH,NCS1,MCU,MCOLN2,PTPRC,CACNB2,BBC3,TRPC1,TMEM37,TRPC3,ATP2B4,ATP2B1,CACNA2D1,DDIT3,DENND5B |
| 7.048e-03 | -4.96 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902236 | 19 | 6 | 17256 | 1658 |
PRKN,WFS1,HERPUD1,LRRK2,MAGEA3,XBP1 |
| 7.057e-03 | -4.95 | lipid binding | molecular function | GO:0008289 | 716 | 90 | 17224 | 1680 |
ARHGAP26,PLA2G4A,DOC2A,SYT12,PLEKHA5,MYO1B,MCOLN3,JCHAIN,ITPR2,SYT14,SNX9,NUP62CL,PCLO,CYP26A1,ZFYVE9,F3,SCIN,GSDME,RIDA,UNC13B,PDZD8,ZFYVE28,STARD4,FABP6,DAB2IP,CLVS2,PACSIN1,TLR4,PLTP,SNX10,HSPA2,RASGRP1,GAB2,FER,CD55,MARK1,PREX1,NFE2L1,PLEKHA1,SNCA,PEMT,PIK3C2B,PXDC1,NR3C2,TC2N,LPAR2,ALOX5AP,STXBP6,MCTP2,OPHN1,SELL,GAS6,PFN2,ARHGAP44,IRX5,TECPR1,SOAT2,MCF2L,RUNDC3B,SGK3,CADPS2,SH3PXD2B,DENND1C,FES,SNX7,ARAP2,MYO10,PLEKHA8,PARD3B,ESRRG,RAPGEF2,CYTH3,PACSIN3,FERMT2,HIP1,NPC2,ARHGAP32,TLR6,PLCB1,LRAT,ID3,SH3GL2,FCHO2,OSBPL5,LAPTM4B,PLD1,FNBP1L,OSBPL6,ABCG1,ATP1A3 |
| 7.063e-03 | -4.95 | RhoGEF | pfam domains | PF00621 | 70 | 14 | 17054 | 1666 |
ARHGEF10L,VAV3,ARHGEF28,FARP1,ARHGEF11,MCF2L2,MCF2L,RASGRF2,SPATA13,PLEKHG1,PREX1,OBSCN,ARHGEF26,TIAM2 |
| 7.081e-03 | -4.95 | ACTGCCT,MIR-34B | MSigDB lists | ACTGCCT,MIR-34B | 208 | 32 | 17377 | 1707 |
MYCBP2,TRIM2,ACSL1,CELSR3,MAPK4,ARHGEF10L,SPEG,NAV1,MAP1A,RALGPS2,HPS1,MYC,LRP6,TOX,MET,MORN4,MYRIP,PAK1,MOB1B,ERGIC1,ANK2,FOXN3,FHL2,ELMOD1,GRID1,PLEKHA1,GLCE,ICA1,KLF12,PTK7,MLLT3,CTNND2 |
| 7.082e-03 | -4.95 | CAIRO_HEPATOBLASTOMA_DN | MSigDB lists | CAIRO_HEPATOBLASTOMA_DN | 249 | 37 | 17377 | 1707 |
ACSL1,AASS,CYP2J2,NSUN6,ASS1,CBS,NDRG2,ABAT,INPP1,CYP26A1,CA2,KMO,EHD3,GHR,PCK2,AGL,IL1RAP,CTH,IGFBP3,SLC27A2,OGDHL,RNF125,C1R,KCND3,SKAP1,SLC46A3,LEPR,ARHGEF26,GPLD1,TSKU,INSIG1,TDO2,RND3,PEMT,HPGD,FAM149A,PPARGC1A |
| 7.109e-03 | -4.95 | cellular response to glucose starvation | biological process | GO:0042149 | 37 | 9 | 17256 | 1658 |
PRKAA2,SESN2,ASNS,ATF4,PMAIP1,BHLHA15,XBP1,NUAK2,SESN1 |
| 7.110e-03 | -4.95 | GO_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_WNT_SIGNALING_PATHWAY | 333 | 47 | 17377 | 1707 |
PRKAA2,TNIK,AMOTL1,CELSR1,LGR4,CELSR3,FZD8,LRP4,RGS20,GATA3,NDRG2,NOTUM,GRK6,KREMEN1,PPP2R3A,DACT1,MYC,LRP6,PRICKLE2,CPE,SNAI2,GLI1,FZD1,DISC1,MARK1,PTPRU,FZD4,WLS,LRRK2,RYR2,PRICKLE1,FERMT2,WNT11,PYGO1,ROR1,PLCB1,GPC6,DKK1,TCF7L1,PTK7,GNAO1,MCC,HOXB9,MAGI2,DDIT3,BTRC,CTNND2 |
| 7.115e-03 | -4.95 | negative regulation of protein kinase activity | biological process | GO:0006469 | 263 | 38 | 17256 | 1658 |
LATS2,DUSP8,UBASH3B,DNAJC3,IPO5,NPM1,CEBPA,PKN1,PPM1E,IGF1R,ZFYVE28,FLRT3,PRKCD,LRP6,DAB2IP,ERRFI1,SPRY2,HMGCR,DUSP1,PTPN6,DEPTOR,PREX1,DUSP9,PRKAR2B,RACK1,WARS,CAMK2N1,PTPRC,TRIB3,PTPRJ,WWTR1,DUSP19,BMP4,SPRY4,TESC,SMYD3,PKIA,SFN |
| 7.116e-03 | -4.95 | regulation of developmental growth | biological process | GO:0048638 | 323 | 45 | 17256 | 1658 |
PRKN,LATS2,FN1,FGF13,BMPR2,PLXNA2,STAT5B,NTRK3,PHLDA2,NKX6-1,RND2,TGFBR3,SEMA4F,GHR,STC2,CTTN,SH3PXD2B,YBX3,WWC2,RIMS2,GLI1,PAK1,BDNF,MSTN,DCC,YAP1,WWC1,PLS1,ZFPM2,SAV1,PLCB1,FGFR1,MAP1B,CSF1,ADRB1,PTPRS,SEMA3C,BMPR1A,BMP4,NRP1,SPART,SEMA3A,SHTN1,TLL2,MEF2C |
| 7.128e-03 | -4.94 | GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ORGANIC_CYCLIC_COMPOUND | 445 | 60 | 17377 | 1707 |
ACVR1,ID1,IL15,GABRB2,RBFOX2,RGS20,MSR1,GABRG2,ASS1,NPM1,CEBPA,ITPR2,P2RY1,MLC1,NEDD4,FBXO32,TLR3,HMGCS1,AKAP7,SGK1,LRP6,ADCY6,GRIP1,KLF9,PDE4D,ERRFI1,ATP2B1,FZD1,CYP1B1,GSTM2,SMAD9,MSTN,HNF4G,NR6A1,NR4A1,RAPGEF2,ESRRG,LRRK2,FHL2,ADCY1,RYR2,MGMT,GPLD1,SNCA,GNAI1,CEBPB,SMAD3,ID3,PMEPA1,TERT,ITGA2,BMP4,PPARGC1A,NR3C2,SMYD3,BTRC,ATP2B4,ATP1A3,MEF2C,HEY1 |
| 7.166e-03 | -4.94 | GSE32986_UNSTIM_VS_GMCSF_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_STIM_DC_UP | 168 | 27 | 17377 | 1707 |
EXPH5,RPS20,PDK1,PNRC1,ACVR1C,RECK,STAT4,APBB1,TCEA3,NDRG2,FAM117B,ABCC2,ARHGAP32,PFN2,CENPV,ZFYVE9,ADAMTS17,RIMKLB,BACH2,RALGPS2,MPP7,RGS10,FHIT,IPCEF1,WWC2,APBA2,NR3C2 |
| 7.166e-03 | -4.94 | CATGTAA,MIR-496 | MSigDB lists | CATGTAA,MIR-496 | 168 | 27 | 17377 | 1707 |
EPHA3,DPP10,BDNF,MEIS2,PLEKHA5,SLITRK5,MAFB,SATB2,PRDM1,TMEM47,KIAA1217,CANX,SEMA6A,HECTD2,ZIC1,HMGCS1,BACH2,FBN1,MAP2,TECPR2,KCNS3,NBEA,TOX,PURG,B4GALT6,HACE1,MEF2C |
| 7.172e-03 | -4.94 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_UP | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_UP | 192 | 30 | 17377 | 1707 |
CARS,SLC3A2,GARS,TTC39B,JDP2,CYTH3,LITAF,ATF3,CTTNBP2NL,SLC7A2,ATP11A,CHAC1,SAV1,CD40,SESN1,CA13,BATF3,TXNRD3,SLC39A14,KPNA3,PLAGL1,PMEPA1,RND3,AKT3,PLK2,ERRFI1,SEMA3A,RBMS2,DDIT3,PHC1 |
| 7.172e-03 | -4.94 | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN | 192 | 30 | 17377 | 1707 |
ARHGAP26,DMXL2,VNN2,MICAL2,RIN2,GCA,GAPDH,LGALS3,FLVCR2,LILRB1,KCTD12,CTBP2,NPC2,ATP10D,TBC1D2,ARHGEF10L,TYMP,FGR,MGAT1,PRKCD,BCL6,RAB31,MARCKS,RNF130,PTPRE,SNX10,SYK,CEBPD,CKAP4,GAB2 |
| 7.172e-03 | -4.94 | GO_ENDOPLASMIC_RETICULUM_LUMEN | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_LUMEN | 192 | 30 | 17377 | 1707 |
COL9A3,COL6A2,COL4A3,TMEM43,SLC27A2,COL4A4,DNAJC3,BACE1,EDEM3,COL18A1,COL4A5,GAS6,CANX,ASPH,COL14A1,COL27A1,TXNDC5,COL22A1,BCHE,COL25A1,P4HA2,P4HA1,RCN3,COL19A1,PTPRN2,SERPINH1,ESD,COL9A2,FKBP14,CES3 |
| 7.186e-03 | -4.94 | neurotransmitter transport | biological process | GO:0006836 | 188 | 29 | 17256 | 1658 |
DOC2A,SV2B,PRKN,SLC6A9,SLC36A1,SYT12,PPFIA4,SNAP25,SLC1A3,SYT14,NRXN1,APBA1,PCLO,SNCA,TRIM9,ICA1,UNC13B,SLC7A11,PPFIA2,PTPRN2,LIN7A,CADPS2,SLC6A15,SEPT5,STXBP1,SYK,TC2N,RIMS2,SNPH |
| 7.190e-03 | -4.94 | V$FREAC7_01 | MSigDB lists | V$FREAC7_01 | 176 | 28 | 17377 | 1707 |
BCL11B,TYRO3,SSH3,RUNX2,MSTN,CHCHD7,RHOBTB1,PLAG1,PACSIN3,FEZ1,LCP2,IKZF2,NOVA1,SEL1L3,HMCN1,BEX2,NEDD4,SMAD3,GALNT1,KCTD15,FLRT3,SLC10A7,DLG2,TNFSF15,ZBTB20,PPP2R2B,ERRFI1,MID1 |
| 7.190e-03 | -4.94 | GSE3982_MAST_CELL_VS_BCELL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_BCELL_DN | 176 | 28 | 17377 | 1707 |
BCL7A,KLF8,EVL,PDK1,SLC37A1,PNRC1,PRSS16,ZNF395,IL15,ARID5B,ATF7IP2,SETBP1,SLC25A28,IL13RA1,SEZ6L2,ZDHHC14,NRXN1,SKAP1,KCNC4,DENND3,JAM3,HOPX,ENTPD1,PPFIBP1,SERINC2,LRRK1,CKAP4,GLDC |
| 7.190e-03 | -4.94 | GSE42724_NAIVE_BCELL_VS_PLASMABLAST_DN | MSigDB lists | GSE42724_NAIVE_BCELL_VS_PLASMABLAST_DN | 176 | 28 | 17377 | 1707 |
PLA2G4A,PAK1,MYO1D,EIF4E3,RHOBTB1,ZCCHC24,CMTM8,GDPD1,LRMP,APBA1,BBS9,SLC46A3,MCU,ZNF569,ZNF362,PLXDC2,TMEM86A,MORN2,SAMD13,RNF130,TPM1,TLR4,ZFP36L2,DCBLD1,CAND2,ATP2B1,PRKACB,MEF2C |
| 7.190e-03 | -4.94 | GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_DN | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_DN | 176 | 28 | 17377 | 1707 |
LONRF1,SFXN4,TCF24,BACE1,ESRP1,SYBU,CBS,CBY1,SLC2A13,KBTBD11,AARS,ARHGEF26,QPRT,CDS1,EFEMP1,AADAT,GPRC5B,EIF4EBP1,SRD5A3,FAM107B,PAM,SQLE,NAP1L3,PCOLCE2,MBOAT2,TNFRSF11A,SLIT2,CTH |
| 7.191e-03 | -4.93 | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | MSigDB lists | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | 184 | 29 | 17377 | 1707 |
MPZL3,GNG12,MYO10,ARHGEF11,ZCCHC24,ST6GAL1,ASS1,PRICKLE1,TDRKH,GABRR2,PLEKHA1,GPSM2,STK24,TMEM154,FRY,GYPC,GNB4,WFS1,GPR155,GAS2L3,ITGB3,SH3BGRL2,TOX,MYO6,FNBP1L,MLLT3,NEB,RASGRP1,ATP2B1 |
| 7.191e-03 | -4.93 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | 184 | 29 | 17377 | 1707 |
TNIK,VNN2,MYCBP2,SERINC5,MXI1,PDK1,ZNF395,KLHL3,GABRB2,ATF7IP2,BNIP3L,CR2,PRKCQ,DOCK2,MMP15,ZNF711,IRS2,AK1,NELL2,TLR3,PDZD8,AKAP7,PRKCB,MCF2L,GNAO1,PDE4D,NR3C2,ZFP36L2,CRYL1 |
| 7.191e-03 | -4.93 | GSE11057_PBMC_VS_MEM_CD4_TCELL_UP | MSigDB lists | GSE11057_PBMC_VS_MEM_CD4_TCELL_UP | 184 | 29 | 17377 | 1707 |
PLA2G4A,RHOBTB1,LPCAT2,LRRK2,LILRB1,MAFB,PRKAR2B,CEBPA,IL13RA1,TMEM170B,WDFY4,DOCK5,RTN1,EPB41L3,CA2,PRKCD,SLC2A6,RAB31,MARCKS,SLC22A15,TNFRSF17,TLR4,FMNL2,FES,SMPDL3A,ZNF385A,TBC1D8,MEF2C,CYP1B1 |
| 7.191e-03 | -4.93 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | 184 | 29 | 17377 | 1707 |
TBKBP1,MYCBP2,AVPI1,PDK1,PNRC1,LGR4,HEBP1,IL13RA1,ATF3,NPC2,ATOH1,SFXN3,HERC6,SATB1,JAM3,PGAP1,PPP1R9A,TPK1,TSKU,RPL34,RPS6KA2,GYPC,IKZF5,INSIG1,DACT1,EIF4EBP1,ADRB1,PCK2,ZNF629 |
| 7.191e-03 | -4.93 | GSE3039_CD4_TCELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_B2_BCELL_DN | 184 | 29 | 17377 | 1707 |
MTG1,RHOQ,LGALS3,EBPL,EPS8,DHCR24,ASS1,IGF2BP2,SMPDL3B,CD53,SCIN,WARS,SKI,TMEM237,CCBE1,ALDOA,TMEM86A,PRELID1,DUSP19,CDH17,OPN3,CNNM2,SQLE,TUFT1,SLC1A5,JAM2,ENO1,LRP12,LPP |
| 7.202e-03 | -4.93 | V$TFIIA_Q6 | MSigDB lists | V$TFIIA_Q6 | 241 | 36 | 17377 | 1707 |
INPPL1,GABRB2,JDP2,PLAG1,OTX1,ZIC2,NRXN1,SP8,FOXP2,ATXN7L1,TUBB4A,PPFIA2,LHX6,CHRDL1,BCL6,GAN,CKAP4,TMEM56,POU3F3,UNC5C,SSH3,BCL7A,MEIS2,NR4A1,FHL2,FGF17,RNF44,GPR19,GJC1,MMP15,ID3,PMEPA1,PELI2,MPP2,MAPK10,OSBPL6 |
| 7.202e-03 | -4.93 | V$NRF2_Q4 | MSigDB lists | V$NRF2_Q4 | 241 | 36 | 17377 | 1707 |
CCDC126,NUDT10,PPP4R4,SEC24D,KIF5A,BLVRB,ASS1,NDRG2,CANX,APBA1,ABHD4,SEL1L3,PFN2,PRR7,PHLDA2,BEX2,TTC1,TECPR1,CACNB2,BNIP3,LOXL4,PPP2R2B,PDE4D,ENO1,SMAD6,GAPDH,MSTN,ESRRG,FGF12,PRDM1,ATP1B1,ZIC1,PKN3,AKT3,ALDOA,SH3BGRL2 |
| 7.203e-03 | -4.93 | negative regulation of collateral sprouting | biological process | GO:0048671 | 9 | 4 | 17256 | 1658 |
PTPRS,SPART,FGF13,DCC |
| 7.203e-03 | -4.93 | striated muscle atrophy | biological process | GO:0014891 | 9 | 4 | 17256 | 1658 |
GSN,PPARGC1A,IL15,MSTN |
| 7.203e-03 | -4.93 | diaphragm development | biological process | GO:0060539 | 9 | 4 | 17256 | 1658 |
ASS1,MSC,DISP1,KCNAB1 |
| 7.203e-03 | -4.93 | regulation of germinal center formation | biological process | GO:0002634 | 9 | 4 | 17256 | 1658 |
PKN1,BCL6,MEF2C,TNFSF13B |
| 7.203e-03 | -4.93 | calcium ion import into cytosol | biological process | GO:1902656 | 9 | 4 | 17256 | 1658 |
FAM155B,FAM155A,ATP2B4,CACNA2D1 |
| 7.203e-03 | -4.93 | calcium ion import across plasma membrane | biological process | GO:0098703 | 9 | 4 | 17256 | 1658 |
FAM155B,FAM155A,ATP2B4,CACNA2D1 |
| 7.203e-03 | -4.93 | regulation of alkaline phosphatase activity | biological process | GO:0010692 | 9 | 4 | 17256 | 1658 |
SMAD3,ITGA2,MEF2C,GPLD1 |
| 7.203e-03 | -4.93 | neuron projection arborization | biological process | GO:0140058 | 9 | 4 | 17256 | 1658 |
NRP1,SEMA3A,ZNF365,LRRK2 |
| 7.226e-03 | -4.93 | DH-domain | interpro domains | IPR000219 | 70 | 14 | 18492 | 1811 |
ARHGEF10L,VAV3,ARHGEF28,FARP1,ARHGEF11,RASGRF2,MCF2L2,MCF2L,PREX1,SPATA13,PLEKHG1,OBSCN,TIAM2,ARHGEF26 |
| 7.242e-03 | -4.93 | mammary gland development | biological process | GO:0030879 | 124 | 21 | 17256 | 1658 |
MSX1,KDM5B,CSN2,FASN,STAT5B,DDR1,MGMT,CEBPB,IRS2,NRG3,CSF1,ATP7B,ITGA2,PAM,HK2,LRP6,BMP4,OXTR,HOXB9,TNFRSF11A,BTRC |
| 7.247e-03 | -4.93 | TFAP2 (AP-2) family regulates transcription of cell cycle factors | REACTOME pathways | R-HSA-8866911 | 5 | 3 | 10287 | 971 |
KDM5B,MYC,TFAP2A |
| 7.264e-03 | -4.92 | GO_ACTIN_CYTOSKELETON | MSigDB lists | GO_ACTIN_CYTOSKELETON | 428 | 58 | 17377 | 1707 |
CGN,GNG12,MYO1D,SORBS1,MYO1B,OPHN1,ADD2,RAC3,PPP1R9A,CTNNA2,ABLIM1,GAS2L3,MYO3B,SMTN,ACTA2,MYH15,MARCKS,SH3PXD2B,CTTN,TLN2,MYO6,MYRIP,NEB,PAK1,PDLIM7,DBN1,FER,SYNPO2,MYLK3,PXN,RHOQ,MYO10,DSTN,FHL2,FERMT2,PLS1,ARHGAP32,CTTNBP2NL,CDC42BPA,INTS6,PALLD,PEAK1,BAIAP2,SNCA,GSN,FGR,PLEKHH2,MYADM,PDLIM3,WIPF3,ALDOA,RAI14,SVIL,MYOM2,TMOD2,TPM1,CDH2,COBL |
| 7.264e-03 | -4.92 | GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 428 | 58 | 17377 | 1707 |
PRKAA2,LATS2,TNIK,NEK10,DYRK3,ACVR1,BMPR2,SLK,CHUK,MAPK4,GRK6,PKN1,PRKCA,STK24,MOK,SPEG,TGFBR3,RPS6KA2,ADCK1,RPS6KL1,PRKCD,SGK3,MYO3B,PRKG1,SGK1,PRKG2,ACVR2A,ALPK1,MAST4,SYK,PRKACB,PAK1,TNK2,MYLK3,MARK1,ACVR1C,LRRK2,NUAK2,OBSCN,STRADB,PRKCQ,ACVR2B,CDC42BPA,SGK2,MAPKAPK2,DYRK1B,PKN3,PRKCB,MAP2K6,AKT3,PLK2,ERN1,NEK11,MAPK13,BMPR1A,LRRK1,MAPK10,MAST1 |
| 7.264e-03 | -4.92 | GO_CALCIUM_CHANNEL_COMPLEX | MSigDB lists | GO_CALCIUM_CHANNEL_COMPLEX | 56 | 12 | 17377 | 1707 |
CACNG3,CACNB2,CACNA1E,RYR2,PDE4D,ASPH,CACNB4,HSPA2,CACNA2D1,HERPUD1,NOS1AP,MCU |
| 7.269e-03 | -4.92 | calcium ion transport | biological process | GO:0006816 | 238 | 35 | 17256 | 1658 |
CACNG3,MCOLN3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,CACNB2,BHLHA15,TRPC1,TMEM37,FAM155B,FAM155A,ATP2B1,TRPM4,GPM6A,SLC3A2,CSN2,ANK2,CACNA1E,JPH1,CALCRL,RASA3,RYR2,PTPRC,CACHD1,ASIC1,GRIN2D,TRPC3,CACNA2D1,ATP2B4,DDIT3,DENND5B,TPT1 |
| 7.278e-03 | -4.92 | voltage-gated sodium channel complex | cellular component | GO:0001518 | 14 | 5 | 18223 | 1724 |
SCN5A,SCN2A,SCN1B,SCN8A,SCN3A |
| 7.306e-03 | -4.92 | bone morphogenesis | biological process | GO:0060349 | 86 | 16 | 17256 | 1658 |
MSX1,INPPL1,RUNX2,BMPR2,FOXN3,CHSY1,BMP6,COL27A1,SKI,INSIG1,TFAP2A,BMP4,SERPINH1,SHOX2,MMP16,MEF2C |
| 7.313e-03 | -4.92 | GO_BONE_MORPHOGENESIS | MSigDB lists | GO_BONE_MORPHOGENESIS | 77 | 15 | 17377 | 1707 |
MSX1,INPPL1,RUNX2,BMPR2,INSIG1,TFAP2A,CHSY1,BMP4,SERPINH1,SHOX2,BMP6,MMP16,COL27A1,SKI,MEF2C |
| 7.313e-03 | -4.92 | chr4q21 | MSigDB lists | chr4q21 | 77 | 15 | 17377 | 1707 |
NKX6-1,NAP1L5,MOB1B,UNC5C,ANTXR2,CXCL10,HPSE,CSN2,ADAMTS3,PTPN13,FRAS1,PRDM8,FAM13A,SNCA,CDS1 |
| 7.313e-03 | -4.92 | GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 77 | 15 | 17377 | 1707 |
SLC7A1,SERINC5,SLC3A2,SLC6A9,SLC7A11,SLC36A1,SLC7A5,SERINC2,SLC36A4,SLC6A15,SLC7A2,SLC1A3,SLC1A5,SLC16A10,SLC43A1 |
| 7.313e-03 | -4.92 | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_DN | 77 | 15 | 17377 | 1707 |
UST,GPR176,ARAP2,SKAP2,FAM168A,LRP6,SFMBT1,ACVR2A,CREB5,CDC42BPA,ROR1,FAM155A,DOCK9,CTIF,HEG1 |
| 7.338e-03 | -4.91 | Myh10 (myosin, heavy polypeptide 10, non-muscle) | protein interactions | 77579 | 141 | 24 | 17029 | 1718 |
DBN1,GNG12,FARP1,AMOTL1,TES,MYO1B,PACSIN3,EFHC1,SNCA,GNAI1,KIAA1958,GSN,ABLIM1,ARHGAP21,GNB4,DSG2,RAI14,SVIL,LIMCH1,CTTN,MYO6,TPM1,COBL,STON2 |
| 7.388e-03 | -4.91 | Metabolism | REACTOME pathways | R-HSA-1430728 | 2158 | 234 | 10287 | 971 |
NMNAT3,UGT8,MVK,ACSL1,ADAL,AASS,UGDH,LDLR,TNFAIP8L2,ASS1,ITPR2,CHAC1,PRKCA,BCAN,ABHD4,QPRT,CYP51A1,TYMP,AADAT,GRHL1,FAAH2,KCNS3,NDUFB8,SERINC2,GSTM3,PLTP,ENO1,PRKACB,GLDC,CYP1B1,SLC3A2,ALDH1L2,GDPD1,PLPP2,HACD1,YAP1,PRKAR2B,SLC25A28,PLEKHA1,GPC6,CA13,GNAI1,PYCR1,AHRR,ENPP1,AK1,HPSE,INSIG1,ENPP6,ENTPD7,GNB4,ALDOA,BDH2,BMP1,PIK3C2B,INPP5F,DSEL,PPARGC1A,CRYL1,HS6ST3,PCSK5,UST,PRKAA2,GPT2,MOCOS,GNG12,INPPL1,ALOX5AP,EHHADH,SEC24D,CYP2J2,ELOVL7,OLAH,DHCR24,CYP4V2,SLC25A27,SCD,ISYNA1,CHSY1,PHGDH,ADSSL1,RPL13A,CA2,MSMO1,BCHE,CACNB2,RPS11,SREBF1,HS3ST5,ADCY6,MED7,NCEH1,FAR2,STXBP1,AGL,RPS23,LRP12,CHRM3,NOS3,HMGCR,CHSY3,FADS1,RPL26,PNP,PLEKHA8,SLC27A2,GSTM4,MGST3,VLDLR,RAPGEF4,FASN,FHL2,SMARCD3,SDC3,LHPP,NPC2,SNAP25,PLCB1,AMDHD1,GLCE,MAPKAPK2,RPL28,GSTO2,MFSD2A,HK2,SQLE,PLD1,DHCR7,OSBPL6,PANK3,AMPD1,ACSM3,PLA2G4A,NUDT10,ELOVL4,AKAP5,LPCAT2,PLEKHA5,XYLT1,LPIN3,NUDT12,SLC19A2,TIAM2,CYP26A1,CDS1,PLPP1,IDI1,ASNS,KMO,ALDOC,FABP6,STARD4,ALDH1L1,MARCKS,RPL26L1,GATM,CTH,HRASLS,RPS13,VNN2,GAPDH,PDK1,UROS,PFKFB2,CYB5R2,MVD,PANK1,ADCY1,GSTO1,ETNPPL,TPK1,ENTPD1,RANBP2,TDO2,PEMT,WWTR1,INPP4B,MAOA,HPGD,CYP2U1,HS3ST3B1,MBOAT2,PSPH,RPS20,MAN2B2,SERINC5,ENO2,GCAT,BLVRB,CBS,ARL2,INPP1,GDPD5,RPL34,HMGCS1,SOAT2,PRKG2,PHYKPL,CERS4,FIG4,PCK2,ESD,SLC45A3,B4GALT6,PCSK6,CES3,PARP9,PFKFB4,OPLAH,GSTM2,ALDH2,HYKK,PTPN13,AGPAT4,CACNA1E,RPL21,ELOVL3,AK4,MARS,LRAT,TRIB3,DDAH1,RPL12,ACER2,SRD5A3,OSBPL5,SLC7A5,RPS12,HK1,RPL4,CERS1,PTGES,B4GALT7,ABCG1 |
| 7.388e-03 | -4.91 | human chr4p15.2 | chromosome location | human chr4p15.2 | 24 | 6 | 26185 | 1967 |
LGI2,SMIM20,ADGRA3,PPARGC1A,SEL1L3,TBC1D19 |
| 7.389e-03 | -4.91 | GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS | 903 | 111 | 17377 | 1707 |
PLA2G4A,NBL1,MVK,CFH,IL15,C4A,VAMP8,TNFAIP8L2,LMCD1,PLXNA2,GATA3,LILRB1,STAT5B,NTRK3,SLC7A2,ABAT,NRXN1,PRKCA,DOCK2,SEMA6A,STK24,CTNNA2,F3,FAM131B,TLR3,BCL6,PROS1,CTTN,MET,TLR4,SLIT2,SEMA6C,PDGFRB,SNAI2,PHLDB2,CD55,GAPDH,LRRK2,BNIP3L,FEZ1,PRKCQ,RARRES2,ATP1B1,F12,JAM3,C4BPB,FGFR1,SMAD3,CXCL10,GPRC5B,HPSE,NCKAP1L,ITGA2,ERN1,TNFRSF1A,SEMA3C,MAPK13,HGF,INPP5F,ATG5,NRP1,SUSD4,TNFSF4,TC2N,LZTS1,PRKAA2,EFNB2,TYRO3,SEMA6B,TNIK,C1QTNF3,BMPR2,ROBO2,FN1,CD276,ST6GAL1,UBASH3B,ATP6V1E2,HERC5,CUEDC2,SLC1A3,GAS6,SPINK5,BMP6,NEDD4,HOPX,MAP1A,SEMA4F,PIK3AP1,PRKCD,SREBF1,PRKG1,BNIP3,ALPK1,TNFRSF11A,SYK,HMGCR,NOS3,VEGFC,QSOX1,MSTN,MPP1,CALCRL,PRDM1,SMPDL3B,RPL28,THBS4,CSF1,SEMA3A,LARP1,STOM |
| 7.400e-03 | -4.91 | GO_RECYCLING_ENDOSOME | MSigDB lists | GO_RECYCLING_ENDOSOME | 114 | 20 | 17377 | 1707 |
TNIK,TUBA1A,SCAMP1,ATP9A,PANK1,VAMP8,ATP11A,DYNC1I1,MLC1,ARHGAP44,SLC9A7,RAB11FIP5,EHD3,RAP2A,SGK3,GRIP1,INPP5F,FIG4,GPR161,ABCG1 |
| 7.400e-03 | -4.91 | GO_EPIDERMAL_CELL_DIFFERENTIATION | MSigDB lists | GO_EPIDERMAL_CELL_DIFFERENTIATION | 114 | 20 | 17377 | 1707 |
EXPH5,PTCH2,BCL11B,INTU,LATS2,ST14,MCOLN3,YAP1,OVOL2,ATOH1,SAV1,PALLD,DSP,SPINK5,FGFR1,PLS3,PDZD7,KAZN,SFN,GLI1 |
| 7.406e-03 | -4.91 | GO_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 63 | 13 | 17377 | 1707 |
PLA2G4A,SORBS1,PRKCD,LDLR,XBP1,TNFRSF1A,SREBF1,PPARGC1A,ABHD6,SLC45A3,BMP6,GPLD1,ABCG1 |
| 7.406e-03 | -4.91 | LIN_NPAS4_TARGETS_DN | MSigDB lists | LIN_NPAS4_TARGETS_DN | 63 | 13 | 17377 | 1707 |
BDNF,SV2B,WIPF3,TMEM86A,OPN3,TMTC4,FHL2,SHISA2,KLF9,ERRFI1,TESC,TMEM56,GLCE |
| 7.411e-03 | -4.90 | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | MSigDB lists | JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | 70 | 14 | 17377 | 1707 |
SLC3A2,COL6A2,ASNS,CFH,VLDLR,LAMB1,VIM,SERPINH1,PHGDH,ADSSL1,CDH2,PDGFRB,GAS1,CYP1B1 |
| 7.411e-03 | -4.90 | ODONNELL_METASTASIS_UP | MSigDB lists | ODONNELL_METASTASIS_UP | 70 | 14 | 17377 | 1707 |
PTCH2,PDLIM7,KLF12,GATA2,NR4A1,FAT1,MYO1B,SHANK2,TMEM143,BBC3,CNNM2,RNF130,CACNB4,TLL2 |
| 7.411e-03 | -4.90 | chr1p31 | MSigDB lists | chr1p31 | 70 | 14 | 17377 | 1707 |
PRKAA2,GNG12,CACHD1,CYP2J2,WLS,LRRIQ3,NFIA,AK4,ST6GALNAC3,SAMD13,TTLL7,LEPR,CTH,NEGR1 |
| 7.411e-03 | -4.90 | TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA | MSigDB lists | TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA | 70 | 14 | 17377 | 1707 |
NKX6-1,NAP1L5,MOB1B,ZNF827,CNTN4,MCF2L2,MYC,ARID5B,RUNDC3B,NFIA,FBXO36,SP8,FSTL5,TBC1D2 |
| 7.524e-03 | -4.89 | human chr13q14.3 | chromosome location | human chr13q14.3 | 39 | 8 | 26185 | 1967 |
SUGT1,FAM124A,CKAP2,ATP7B,ALG11,DHRS12,INTS6,THSD1 |
| 7.525e-03 | -4.89 | negative regulation of insulin receptor signaling pathway | biological process | GO:0046627 | 31 | 8 | 17256 | 1658 |
ENPP1,MSTN,PRKCB,GRB14,PRKCD,PRKCQ,GRB10,PTPRE |
| 7.525e-03 | -4.89 | regulation of keratinocyte proliferation | biological process | GO:0010837 | 31 | 8 | 17256 | 1658 |
BCL11B,INTU,CTSV,YAP1,OVOL2,KLF9,SFN,SNAI2 |
| 7.525e-03 | -4.89 | forebrain neuron development | biological process | GO:0021884 | 31 | 8 | 17256 | 1658 |
ROBO2,RAPGEF2,LHX6,NRP1,FOXG1,SEMA3A,RAC3,SLIT2 |
| 7.525e-03 | -4.89 | muscle adaptation | biological process | GO:0043500 | 31 | 8 | 17256 | 1658 |
GSN,IL15,MSTN,INPP5F,PPARGC1A,GATM,MEF2C,NOS3 |
| 7.527e-03 | -4.89 | GO_RESPONSE_TO_LIPID | MSigDB lists | GO_RESPONSE_TO_LIPID | 867 | 107 | 17377 | 1707 |
EPHA3,PLA2G4A,ACVR1,ACSL1,TRIM16,IL15,RBFOX2,GATA3,LILRB1,ASS1,CHUK,STAT5B,NTRK3,F3,FBXO32,TGFBR3,GSTM3,DAB2IP,PROS1,PDE4D,TLR4,SLIT2,PDGFRB,NKX2-1,FZD1,GDAP1,FER,PTPRU,NR6A1,FZD4,GJB2,ADCY1,YAP1,WNT11,ABCC2,CD40,SNCA,GNAI1,CXCL10,PTK7,ITGA2,TNFRSF1A,PAM,OXTR,TNFSF4,PPARGC1A,NR3C2,PSPH,HEY1,MEF2C,PRKAA2,GNG12,PLSCR4,FN1,TNFRSF10C,MLC1,BMP6,NEDD4,HMGCS1,CA2,EEF2,BCHE,GATA2,DSG2,GHR,STC2,TFAP2A,SREBF1,GRIP1,ADCY6,LRP6,SGK1,KLF9,ERRFI1,GFI1,SMAD6,AGL,TNFRSF11A,ATP2B1,DUSP1,NOS3,FGFR4,MSTN,HNF4G,NR4A1,ESRRG,VLDLR,FHL2,LITAF,CPEB1,GPLD1,DKK1,CEBPB,MAPKAPK2,MMP15,ID3,PMEPA1,ACER2,XBP1,BMP4,CMPK2,TESC,PTGES,SMYD3,FOXA1,ATP1A3,ABCG1 |
| 7.544e-03 | -4.89 | FOSTER_TOLERANT_MACROPHAGE_UP | MSigDB lists | FOSTER_TOLERANT_MACROPHAGE_UP | 145 | 24 | 17377 | 1707 |
ACSL1,MSR1,SELL,ASS1,SLC7A2,C3orf70,CLN5,DCBLD2,ISG20,ATXN7L1,MCOLN2,ID3,SLC7A11,PIK3AP1,SGK1,FBRSL1,CTTN,GEM,IQSEC2,MET,SMAD6,PTGES,SYK,RASGRP1 |
| 7.575e-03 | -4.88 | Glutathione conjugation | REACTOME pathways | R-HSA-156590 | 38 | 9 | 10287 | 971 |
OPLAH,GSTM2,GSTO2,MGST3,GSTM4,GSTM3,GSTO1,CHAC1,ESD |
| 7.577e-03 | -4.88 | LATS1 (large tumor suppressor kinase 1) | protein interactions | 9113 | 104 | 19 | 17029 | 1718 |
MOB1B,CGN,LATS2,AMOTL1,PTPN13,NUAK2,ASS1,YAP1,WWC1,SAV1,MAGI3,NEDD4,PATJ,SIPA1L2,MYC,EIF4EBP1,WWTR1,WWC2,KIAA1549 |
| 7.581e-03 | -4.88 | nicotinamide nucleotide metabolic process | biological process | GO:0046496 | 109 | 19 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,PFKFB2,OGDHL,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,MDH1B,PCK2,ENO1,PARP9,NUDT17 |
| 7.581e-03 | -4.88 | pyridine nucleotide metabolic process | biological process | GO:0019362 | 109 | 19 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,PFKFB2,OGDHL,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,MDH1B,PCK2,ENO1,PARP9,NUDT17 |
| 7.596e-03 | -4.88 | GO_HEART_MORPHOGENESIS | MSigDB lists | GO_HEART_MORPHOGENESIS | 209 | 32 | 17377 | 1707 |
ACVR1,GATA3,PKP2,OVOL2,NEDD4,TGFBR3,SETDB2,CPE,SNAI2,FZD1,MICAL2,MSX1,DCHS1,FHL2,YAP1,SMARCD3,RYR2,WNT11,SAV1,ZFPM2,DSP,HEG1,SMAD3,FAT4,HEYL,SEMA3C,BMP4,BMPR1A,TPM1,SHOX2,MEF2C,HEY1 |
| 7.596e-03 | -4.88 | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | 209 | 32 | 17377 | 1707 |
ACSL1,MRC2,RUNX2,IGFBP6,LGALS3,SEC24D,ST14,TES,PTPN6,BLVRB,MSR1,FHL2,YAP1,MAFB,NPC2,BATF,LCP2,DCBLD2,PLS3,CEBPB,PTPRC,TYMP,MGAT1,P4HA2,WWTR1,LAMB1,TNFRSF1A,MAPK13,NRP1,TLR4,TNFRSF11A,FES |
| 7.602e-03 | -4.88 | negative regulation of peptidyl-serine phosphorylation | biological process | GO:0033137 | 25 | 7 | 17256 | 1658 |
HGF,INPP5F,PDE4D,RACK1,CNKSR3,DKK1,DDIT4 |
| 7.613e-03 | -4.88 | STREICHER_LSM1_TARGETS_UP | MSigDB lists | STREICHER_LSM1_TARGETS_UP | 43 | 10 | 17377 | 1707 |
KDM5B,FGF13,GATA2,FOXN3,INPP4B,BCL6,GATA3,IL13RA1,SATB1,NR3C2 |
| 7.619e-03 | -4.88 | LIM_DOMAIN_1 | prosite domains | PS00478 | 72 | 15 | 12060 | 1278 |
PDLIM7,ABLIM1,MICAL2,PXN,PDLIM3,TES,CRIP2,LHX6,LMCD1,FHL2,PRICKLE1,PRICKLE2,LIMCH1,CSRP2,LPP |
| 7.619e-03 | -4.88 | LIM_DOMAIN_2 | prosite domains | PS50023 | 72 | 15 | 12060 | 1278 |
PDLIM7,MICAL2,ABLIM1,PXN,PDLIM3,TES,CRIP2,LHX6,FHL2,LMCD1,PRICKLE1,PRICKLE2,LIMCH1,CSRP2,LPP |
| 7.628e-03 | -4.88 | cellular response to carbohydrate stimulus | biological process | GO:0071322 | 79 | 15 | 17256 | 1658 |
PRKAA2,IRS2,RAB11FIP5,IGF1R,UNC13B,MAP2K6,XBP1,ERN1,PTPRN2,CALCRL,MAPK13,GAS6,RACK1,PCK2,PPARGC1A |
| 7.628e-03 | -4.88 | regulation of response to endoplasmic reticulum stress | biological process | GO:1905897 | 79 | 15 | 17256 | 1658 |
PRKN,ATF4,PMAIP1,WFS1,DNAJC3,ERN1,LRRK2,MAGEA3,XBP1,UBAC2,DAB2IP,ATF3,RACK1,HERPUD1,DDIT3 |
| 7.630e-03 | -4.88 | regulation of neural crest cell differentiation | biological process | GO:1905292 | 5 | 3 | 17256 | 1658 |
SEMA3C,BMPR1A,BMP4 |
| 7.630e-03 | -4.88 | isopentenyl diphosphate metabolic process | biological process | GO:0046490 | 5 | 3 | 17256 | 1658 |
IDI1,MVK,MVD |
| 7.630e-03 | -4.88 | membrane depolarization during AV node cell action potential | biological process | GO:0086045 | 5 | 3 | 17256 | 1658 |
TRPM4,SCN5A,CACNB2 |
| 7.630e-03 | -4.88 | negative regulation of tubulin deacetylation | biological process | GO:1904428 | 5 | 3 | 17256 | 1658 |
BEX4,PRKAA2,FRY |
| 7.630e-03 | -4.88 | radial glia guided migration of Purkinje cell | biological process | GO:0021942 | 5 | 3 | 17256 | 1658 |
RBFOX2,CTNNA2,RERE |
| 7.630e-03 | -4.88 | galactolipid biosynthetic process | biological process | GO:0019375 | 5 | 3 | 17256 | 1658 |
UGT8,B3GALT1,B3GALT2 |
| 7.630e-03 | -4.88 | bundle of His cell action potential | biological process | GO:0086043 | 5 | 3 | 17256 | 1658 |
TRPM4,SCN5A,CACNA2D1 |
| 7.630e-03 | -4.88 | aromatic amino acid transport | biological process | GO:0015801 | 5 | 3 | 17256 | 1658 |
SLC36A4,SLC3A2,SLC16A10 |
| 7.630e-03 | -4.88 | gamma-aminobutyric acid metabolic process | biological process | GO:0009448 | 5 | 3 | 17256 | 1658 |
ABAT,SLC1A3,PHGDH |
| 7.630e-03 | -4.88 | dichotomous subdivision of terminal units involved in salivary gland branching | biological process | GO:0060666 | 5 | 3 | 17256 | 1658 |
SEMA3C,NRP1,SEMA3A |
| 7.630e-03 | -4.88 | regulation of gamma-delta T cell differentiation | biological process | GO:0045586 | 5 | 3 | 17256 | 1658 |
STAT5B,NCKAP1L,SYK |
| 7.630e-03 | -4.88 | isopentenyl diphosphate biosynthetic process | biological process | GO:0009240 | 5 | 3 | 17256 | 1658 |
IDI1,MVK,MVD |
| 7.630e-03 | -4.88 | axonogenesis involved in innervation | biological process | GO:0060385 | 5 | 3 | 17256 | 1658 |
NRP1,SEMA3A,COL25A1 |
| 7.630e-03 | -4.88 | galactosylceramide biosynthetic process | biological process | GO:0006682 | 5 | 3 | 17256 | 1658 |
UGT8,B3GALT1,B3GALT2 |
| 7.630e-03 | -4.88 | negative regulation of guanyl-nucleotide exchange factor activity | biological process | GO:1905098 | 5 | 3 | 17256 | 1658 |
RIPOR2,MET,GPSM1 |
| 7.630e-03 | -4.88 | bundle of His cell to Purkinje myocyte signaling | biological process | GO:0086028 | 5 | 3 | 17256 | 1658 |
TRPM4,SCN5A,CACNA2D1 |
| 7.630e-03 | -4.88 | dendrite arborization | biological process | GO:0140059 | 5 | 3 | 17256 | 1658 |
NRP1,SEMA3A,ZNF365 |
| 7.651e-03 | -4.87 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN | 292 | 42 | 17377 | 1707 |
CGN,MYO1D,KLF8,DHCR24,ASS1,DNER,ADSSL1,FAM174B,ABLIM1,TACC2,BACE2,ALDH1L1,NBEA,MORN2,MDH1B,VWA5A,FANK1,DNAH5,B9D1,CDH26,CD55,TUBA1A,EML6,SLC27A2,SYBU,CAPN5,TCEA3,CR2,EFHC1,ZBBX,TEX9,C9orf116,ARMC4,TMEM154,LRRIQ3,AHNAK2,PTPRN2,NEK11,FAM149A,COBL,SIX2,CRYL1 |
| 7.693e-03 | -4.87 | BTNL8 (butyrophilin like 8) | protein interactions | 79908 | 42 | 10 | 17029 | 1718 |
TCTN2,CNTNAP3,PTK7,ITGA6,ITGA2,CNNM2,RNF130,LEPR,PGAP1,CACNA2D1 |
| 7.715e-03 | -4.86 | AP-1 | interpro domains | IPR000837 | 9 | 4 | 18492 | 1811 |
ATF3,BATF,JDP2,BATF3 |
| 7.715e-03 | -4.86 | GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_DN | MSigDB lists | GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_DN | 161 | 26 | 17377 | 1707 |
CHSY3,DISC1,SEMA6B,TMEM132C,ABCC4,KCNQ3,PTPRD,EFNA3,NFE2L1,FAM102B,TMEM200C,KHDRBS2,GPC6,FKBP11,RNF150,IQCK,PCDHB7,ADCK1,PMAIP1,PELI2,SAMD11,FAM133A,DBP,CERS1,TESC,TBC1D8 |
| 7.715e-03 | -4.86 | GO_MYELIN_SHEATH | MSigDB lists | GO_MYELIN_SHEATH | 161 | 26 | 17377 | 1707 |
SERINC5,MYO1D,TUBA1A,ENO2,GSTO1,SNAP25,ATP1B1,CANX,PHGDH,PLCB1,JAM3,CA13,TUBB4A,GSN,CA2,GNAO1,MARVELD2,GNB4,EHD3,MPDZ,PACSIN1,STXBP1,ENO1,HSPA2,ATP1A3,CNTN1 |
| 7.715e-03 | -4.86 | GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP | MSigDB lists | GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP | 161 | 26 | 17377 | 1707 |
TNIK,EML5,AMOTL1,PDK1,ST6GAL1,ITGA6,RAPGEF4,MCOLN3,SELL,TDRKH,PLEKHA1,SESN1,ID3,TGFBR3,RALGPS2,PMEPA1,MYC,CACNB2,RGS10,INPP4B,ADCY6,TOX,IPCEF1,DISP2,DIRC2,AMPD1 |
| 7.715e-03 | -4.86 | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP | MSigDB lists | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP | 161 | 26 | 17377 | 1707 |
ANTXR2,RNF144A,TES,RAPGEF2,STAT4,ATOX1,PRRG1,AK4,NOTUM,PALLD,KREMEN1,SCIN,CPNE2,IGF1R,GATA2,MAP2K6,PLXDC2,CSF1,UACA,HS3ST3B1,ALPK1,IQSEC2,TLN2,PDGFRB,RAB30,ATP1A3 |
| 7.716e-03 | -4.86 | GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | MSigDB lists | GO_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 193 | 30 | 17377 | 1707 |
PAK1,TNIK,EDA2R,FZD4,GRIK2,FZD8,PKN1,EPHB1,TLR6,TPD52L1,PLCB1,TNFRSF19,MAGI3,MECOM,TLR3,IGF1R,SH3RF1,MYC,DACT1,RAP2A,ERN1,DUSP19,DAB2IP,HGF,TLR4,TNFRSF11A,MID1,SYK,RASGRP1,HMGCR |
| 7.716e-03 | -4.86 | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_DN | 193 | 30 | 17377 | 1707 |
FADS1,SESN2,MVK,PDE1B,PLEKHA5,MVD,DHCR24,TTC22,COTL1,ABHD4,TLR6,PRRG4,STK24,SPIRE1,HERPUD1,GPR15,MCOLN2,TIFA,INSIG1,CSF1,ITGA2,STARD4,BCL6,ACTA2,NCEH1,PCK2,SLC1A5,STOM,HMGCR,CYP1B1 |
| 7.716e-03 | -4.86 | GSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | MSigDB lists | GSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | 193 | 30 | 17377 | 1707 |
PCDH10,GSTM2,ANKRD13B,CKAP2,VLDLR,EFHC2,KIAA1324L,DEPTOR,CLSTN2,GTF2IRD1,CHRNA6,ACVR2B,PHGDH,RAC3,NEDD4,COL27A1,HSPA12B,PCDH7,DOCK7,UNC13B,RNF217,CHRNA5,GTSF1,SLC16A2,ALDOC,EMILIN2,ZNF518B,FES,CACNA2D1,ACSM3 |
| 7.720e-03 | -4.86 | Endochondral Ossification | WikiPathways | WP474 | 65 | 14 | 5312 | 569 |
ENPP1,HMGCS1,RUNX2,IGF1R,NKX3-2,CTSV,GHR,STAT5B,BMPR1A,SERPINH1,BMP6,FGFR1,MEF2C,SCIN |
| 7.730e-03 | -4.86 | Myo1c (myosin IC) | protein interactions | 17913 | 134 | 23 | 17029 | 1718 |
DBN1,MYO1B,JPH1,ITPR2,MTUS1,TRPS1,GSN,ABLIM1,ARHGAP21,DOCK7,FCHO2,PPFIBP1,GAS2L3,RAI14,SVIL,LIMCH1,CTTN,MYO6,TPM1,RRAS2,COBL,STON2,KIAA1211 |
| 7.738e-03 | -4.86 | ADP metabolic process | biological process | GO:0046031 | 44 | 10 | 17256 | 1658 |
GAPDH,ENO2,PFKFB2,ALDOC,ALDOA,OGDHL,HK2,PGM2L1,HK1,ENO1 |
| 7.738e-03 | -4.86 | actin polymerization or depolymerization | biological process | GO:0008154 | 44 | 10 | 17256 | 1658 |
WASF3,MICAL2,GSN,EVL,CAP2,DSTN,PREX1,COBLL1,CTTN,COBL |
| 7.738e-03 | -4.86 | exocrine system development | biological process | GO:0035272 | 44 | 10 | 17256 | 1658 |
TFCP2L1,EDA,WLS,XBP1,RAB26,SEMA3C,NRP1,SEMA3A,FGFR1,IGSF3 |
| 7.750e-03 | -4.86 | GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_DN | MSigDB lists | GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_DN | 185 | 29 | 17377 | 1707 |
CREB3L2,EML5,LATS2,TRIM2,RAB6B,PSTPIP2,PTPN13,APBB1,PANK1,TTYH2,STAT5B,IKZF2,COL27A1,TXNRD3,ZFP62,CAMK2N1,OTUD1,ZNF827,PLAGL1,TERT,GPR155,MATN2,INPP4B,SH3BGRL2,INPP5F,ZBTB20,PJA1,NR3C2,DUSP1 |
| 7.750e-03 | -4.86 | GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_TGFB1_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | 185 | 29 | 17377 | 1707 |
MAN2B2,RGS16,BCL7A,TNK2,FN1,CSN2,MYO10,GRIK2,ZCCHC24,WWC1,PDE8A,TNFRSF10C,SNAP25,PGAP1,HOXA1,DCBLD2,PCDH7,GJC1,PLS3,ISG20,MSC,ID3,ERN1,LAPTM4B,EPHB6,IPCEF1,POU2F2,VWA5A,CNTN1 |
| 7.750e-03 | -4.86 | GSE3982_DC_VS_BASOPHIL_UP | MSigDB lists | GSE3982_DC_VS_BASOPHIL_UP | 185 | 29 | 17377 | 1707 |
FGFR4,QSOX1,CELSR1,GALNT12,GTF2IRD1,LAMC3,PDE8A,TNS1,ATF3,SLC1A3,ABHD6,COL14A1,PPP2R3A,WARS,ARHGEF10L,FKBP9,KMO,NDUFB8,RAI14,ACVR2A,MAOA,PCOLCE2,PCK2,ESD,STXBP1,ENO1,SPRY2,MEF2C,LPP |
| 7.750e-03 | -4.86 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_DN | 185 | 29 | 17377 | 1707 |
ITGB7,LPAR2,ALDH2,ALOX5AP,IL15,GPR65,ATP8A1,SELL,HERC5,CD40,FKBP11,WARS,CXCL10,TYMP,ASNS,KIAA0355,GBP1,TSC22D1,HK2,SP140,PTPRCAP,APBA2,SNX10,DDIT3,CKAP4,SP140L,GPR161,ABCG1,STOM |
| 7.750e-03 | -4.86 | GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_DN | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_DN | 185 | 29 | 17377 | 1707 |
PRKAA2,SYNPO2,ESRRG,IPO5,PACSIN3,SMARCD3,FERMT2,STRADB,CHAC1,KIAA1217,KCNC4,SEL1L3,SATB1,DHX32,SMAD3,SPEG,AK1,POPDC3,REEP1,ALDH1L1,EEPD1,TMEM117,SVIL,UACA,KIF1B,DIRC2,BOD1,RRAGD,MEF2C |
| 7.750e-03 | -4.86 | GSE14308_TH1_VS_TH17_UP | MSigDB lists | GSE14308_TH1_VS_TH17_UP | 185 | 29 | 17377 | 1707 |
SH3BP2,IGFBP6,ST14,SEC24D,TES,NLRP14,ZNF565,KCTD12,SHISA2,MFSD6,NHP2,BCAN,PHGDH,NEDD4,WARS,HPSE,CSF1,PRELID2,STARD4,RAP2A,TMEM37,ENO1,SPRY2,COBL,NEB,LARP1,GAB2,DUSP1,BOD1 |
| 7.750e-03 | -4.86 | GSE3982_MAC_VS_TH1_UP | MSigDB lists | GSE3982_MAC_VS_TH1_UP | 185 | 29 | 17377 | 1707 |
TRDMT1,GCA,GNG12,VAV3,TUBA1A,RASAL2,ZHX3,RGS20,NDRG2,CEBPA,SESN1,EYA4,TPK1,HOMER3,TXNRD3,RTN1,ENTPD7,DACT1,WWTR1,ITGB3,TNFRSF1A,KLF9,TLN2,MYO6,TLR4,SPRY2,KIF1B,GATM,CES3 |
| 7.750e-03 | -4.86 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN | 185 | 29 | 17377 | 1707 |
TFCP2L1,VAV3,ZNF395,RHOBTB1,MPP1,CYTH3,ARID5B,EPS8,YPEL2,PREX1,GTF2IRD1,PLS1,TNS1,LACC1,TBC1D16,IL18R1,SNCA,SKI,GBGT1,FCHO2,PLOD2,SGK3,SH3PXD2B,TMEM37,VWA5A,SLC16A10,CRYL1,DUSP1,GAB2 |
| 7.753e-03 | -4.86 | GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_UP | MSigDB lists | GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_UP | 169 | 27 | 17377 | 1707 |
TTC39B,LGALS3,AGPAT4,LRP4,VLDLR,CBS,RNF24,SPATS2L,FAM110B,BMP6,CENPV,TMEM74,BATF3,CEBPB,SPNS1,MSC,MGAT1,WFS1,SERINC2,SVIL,MAOA,PCOLCE2,SEPT3,RNF157,TMEM120B,PTPRE,RNF122 |
| 7.753e-03 | -4.86 | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 169 | 27 | 17377 | 1707 |
BCL7A,MYO1D,RASAL2,RNF145,FLVCR2,GALNT6,ZCCHC24,LITAF,NPM1,BATF,BMP6,ATXN7L1,PCDHB14,EPB41L3,RSL24D1,PTPRJ,FCHO2,TDO2,PPFIBP1,C1orf53,PAM,SVIL,MAOA,THAP10,PERP,MED12L,HEY1 |
| 7.763e-03 | -4.86 | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | MSigDB lists | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_UP | 177 | 28 | 17377 | 1707 |
TYRO3,PAGE1,ENO2,BMPR2,CLGN,RAPGEF2,C3orf52,SSX1,PKP2,FERMT2,MAFB,ATF3,SLC12A6,TTLL7,CYP26A1,MOK,CDR2L,AK1,KLF12,PMEPA1,CLMN,SERPINI1,INPP5F,OXTR,LIFR,HSPA2,CSRP2,GAB2 |
| 7.763e-03 | -4.86 | GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | 177 | 28 | 17377 | 1707 |
SEMA6B,USP2,ST6GAL1,XYLT1,EPS8,RASA3,ARL2,HIP1,CEBPA,COTL1,ZDHHC14,COL14A1,RNF150,GSN,ICA1,HPSE,RAP2A,RGS10,ZDHHC23,SGK3,PDE4D,NCEH1,VWA5A,VGLL4,TSPAN9,SPRY2,ZFP36L2,SMPDL3A |
| 7.763e-03 | -4.86 | GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP | MSigDB lists | GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP | 177 | 28 | 17377 | 1707 |
SUSD3,MPZL3,VNN2,ITGB7,CARD6,CD55,PNP,ZNF395,BMPR2,HEBP1,SPATA13,MEI1,RASA3,NDRG2,PDE8A,ADAMTS6,SYNJ2BP,AMIGO1,COTL1,NPDC1,RPL13A,ISG20,BAG3,GYPC,RPS11,FAM107B,PTPRN2,RPL4 |
| 7.763e-03 | -4.86 | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_DN | 177 | 28 | 17377 | 1707 |
CXCR5,PLA2G4A,IL15,STAT4,ARHGAP22,PPFIBP2,FERMT2,AK4,COBLL1,CHAC1,BATF,HERC6,FNDC3A,DDX60L,STEAP1,TIAM2,EPB41L3,NAV1,BACH2,CNKSR3,TNFSF15,GRB10,MET,ZNF701,PERP,KIAA1211,LAMP3,PARP9 |
| 7.771e-03 | -4.86 | positive regulation of steroid biosynthetic process | biological process | GO:0010893 | 14 | 5 | 17256 | 1658 |
PPARGC1A,BMP6,STARD4,ABCG1,SREBF1 |
| 7.771e-03 | -4.86 | atrial cardiac muscle cell to AV node cell signaling | biological process | GO:0086026 | 14 | 5 | 17256 | 1658 |
SCN5A,KCNN2,CACNB2,ANK2,GJC1 |
| 7.771e-03 | -4.86 | GABAergic neuron differentiation | biological process | GO:0097154 | 14 | 5 | 17256 | 1658 |
DLX2,GATA2,RAC3,LHX6,NKX2-1 |
| 7.771e-03 | -4.86 | insulin-like growth factor receptor signaling pathway | biological process | GO:0048009 | 14 | 5 | 17256 | 1658 |
GRB10,IGF1R,CRIM1,PLCB1,GHR |
| 7.771e-03 | -4.86 | positive regulation of neuron migration | biological process | GO:2001224 | 14 | 5 | 17256 | 1658 |
DAB2IP,SEMA3A,RAPGEF2,SEMA6A,SHTN1 |
| 7.771e-03 | -4.86 | atrial cardiac muscle cell action potential | biological process | GO:0086014 | 14 | 5 | 17256 | 1658 |
SCN5A,KCNN2,CACNB2,ANK2,GJC1 |
| 7.776e-03 | -4.86 | GML (glycosylphosphatidylinositol anchored molecule like) | protein interactions | 2765 | 24 | 7 | 17029 | 1718 |
TMEM67,GAS6,TUBA1A,CNTNAP3,FAT1,FRAS1,ITGA6 |
| 7.817e-03 | -4.85 | purine nucleotide binding | molecular function | GO:0017076 | 1854 | 211 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,BAG3,RPS6KA2,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,FAM114A2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,GRPEL2,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 |
| 7.849e-03 | -4.85 | GTCAACC,MIR-380-5P | MSigDB lists | GTCAACC,MIR-380-5P | 19 | 6 | 17377 | 1707 |
MICAL2,TRIM2,KLHL13,HOXA1,FRAS1,PLAG1 |
| 7.849e-03 | -4.85 | REACTOME_CGMP_EFFECTS | MSigDB lists | REACTOME_CGMP_EFFECTS | 19 | 6 | 17377 | 1707 |
PRKG2,KCNMB4,PDE1B,PDE10A,KCNMB3,PRKG1 |
| 7.849e-03 | -4.85 | SHIN_B_CELL_LYMPHOMA_CLUSTER_9 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_9 | 19 | 6 | 17377 | 1707 |
CXCR5,IKZF3,CD40,REL,NKX3-2,BCL11A |
| 7.849e-03 | -4.85 | GO_POSITIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_EPIDERMAL_CELL_DIFFERENTIATION | 19 | 6 | 17377 | 1707 |
PTCH2,OVOL2,ATOH1,BMP4,TRIM16,SFN |
| 7.888e-03 | -4.84 | GO_CIRCULATORY_SYSTEM_PROCESS | MSigDB lists | GO_CIRCULATORY_SYSTEM_PROCESS | 352 | 49 | 17377 | 1707 |
SCN5A,BMPR2,PKP2,ABAT,P2RY1,GAS6,RPS6KA2,SCN1B,CACNB2,PRKG1,ACTA2,SGK1,ADCY6,PDE4D,SLIT2,CHRM3,NOS3,TBC1D8,HMGCR,NKX2-1,TRPM4,VEGFC,MYLK3,COL4A3,ADM2,ANK2,FGF12,RYR2,PRKCQ,ATP1B1,DOCK5,HEG1,GJC1,HTR7,CXCL10,DDAH1,PTPRJ,KCNMB4,MAP2K6,PRCP,ADRB1,OXTR,ATG5,TPM1,MME,CACNA2D1,ATP1A3,ACSM3,PCSK5 |
| 7.889e-03 | -4.84 | superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | BIOCYC pathways | HUMAN_PWY-5910 | 12 | 5 | 902 | 105 |
HMGCS1,IDI1,MVK,MVD,HMGCR |
| 7.889e-03 | -4.84 | superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | BIOCYC pathways | META_PWY-5910 | 12 | 5 | 902 | 105 |
HMGCS1,IDI1,MVK,MVD,HMGCR |
| 7.922e-03 | -4.84 | carbon-oxygen lyase activity | molecular function | GO:0016835 | 71 | 14 | 17224 | 1680 |
CA2,EHHADH,ENO2,UROS,APLF,HACD1,ACO1,FASN,CBS,TGDS,CA8,ENO1,ETNPPL,CA13 |
| 7.933e-03 | -4.84 | VANTVEER_BREAST_CANCER_ESR1_DN | MSigDB lists | VANTVEER_BREAST_CANCER_ESR1_DN | 226 | 34 | 17377 | 1707 |
CREB3L2,UGT8,ST14,TBC1D1,ASS1,GPR180,GPSM2,PHGDH,ASNS,STEAP3,ST8SIA1,PLTP,ENO1,LAMP3,GAPDH,RNF145,RAB6B,MYO10,CYB5R2,TES,DUSP9,PHACTR2,UCHL3,BCL11A,WARS,INHBC,GPRC5B,GBP1,SLC2A6,PLEKHG1,NCOA7,KIF1B,MID1,CSRP2 |
| 7.949e-03 | -4.83 | SH3/SH2 adaptor activity | molecular function | GO:0005070 | 57 | 12 | 17224 | 1680 |
CHN1,VAV3,SH3BP2,CHN2,SORBS1,SKAP2,SH2D2A,GRB14,EPS8,SHF,GRB10,SKAP1 |
| 7.953e-03 | -4.83 | thyroid | COSMIC cancer mutations | thyroid | 10137 | 1037 | 17385 | 1698 |
ARHGAP26,TRIM16L,GRIK2,CNTNAP3,RECK,MCOLN3,ALG1L,NPM1,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,ABHD6,SKI,TMEM37,CPE,POU3F3,DCC,KLHL23,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,PYCR1,ENPP1,WIPF3,ATP7B,ADRB1,BBC3,ERCC5,INPP5F,CAB39L,TPM1,DNHD1,SCN5A,TMEM63C,ITGA6,TJP1,GPSM2,BBS9,HPCAL4,CHN1,FRY,FLRT3,SRGAP1,ALPK1,DENND1C,MOXD1,JAM2,ARID5B,FASN,AIG1,SHISA2,ZBBX,ARRDC4,CLN5,SPATA7,C11orf45,CACHD1,TEX15,GSTO2,RPL28,LAPTM4B,CDH2,DOCK9,MTG1,ADD2,GRK6,TLR3,MAGEA3,ALDH1L1,FAM133A,DNAH5,ZNF365,MYT1,ANKRD18B,FZD1,C3orf67,MYLK3,COL6A2,GAPDH,EBPL,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,SLC39A14,PDLIM3,WFS1,LAMB1,FAM149A,CGB2,CCDC148,ANKRD13B,WDR17,GCAT,FZD8,ESRP1,CD276,PLAG1,PSD3,CBS,SLC12A6,EPHB1,ZNF219,LRRN1,GHR,ZFP36L2,C15orf41,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,NDRG2,MGAT5B,ITPR2,FAM13A,CCNJ,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,CPVL,SEC16B,ITGB3,TMEM143,JAKMIP2,TMEM132E,ENO1,PGBD5,DBN1,KCNIP3,ATF4,PNRC1,COL4A3,SPOCD1,ANK2,TMEM200C,CR2,SESN1,SPNS1,DYRK1B,TCF7L1,KCNMB4,ERN1,AHNAK2,NEUROG2,RRAGD,LONRF1,RUNX2,LGALS3,STXBP5L,SORBS3,ZNF215,ZIC2,DOK5,FHOD3,NUMBL,GALNT1,ZBTB38,FRAS1,GAN,HS3ST5,SMTN,LRP6,FAR2,VGLL4,CKAP4,DPYSL5,BTNL9,GPSM1,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,DOCK1,RHPN2,NTRK3,KIF21B,DENND3,FAM110B,RADIL,TNKS1BP1,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,MYH15,SNAI2,IGFBP3,INTU,LRRC8B,PRDM13,ACO1,RNF125,VIM,IFT81,PTPRJ,PTPRS,MAOA,HGF,SUSD4,MBOAT2,CTNND2,TENM1,SLC6A9,KLHL13,MCTP2,PRDM8,USP30,FOXP2,TFAP2A,GTF2F2,TSC22D1,SGK1,KIAA0408,SYK,LRRIQ1,CRIP2,PRICKLE1,PALLD,ILDR2,MGMT,SMPDL3B,HOMER3,EBF1,DOCK7,FBN1,SLC1A5,PTGES,KIF1B,CACNA2D1,ZNF235,FAM171B,PLBD2,LGR4,LDLR,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,C1orf53,SERINC2,KCNS3,THSD1,GLDC,GDAP1,ERGIC1,WISP3,KLHL3,FAM84A,LRMP,ZDHHC14,SH3RF1,ENPP6,BMP1,MAPK13,DSEL,NRP1,SPOCK3,SEMA6B,LRFN5,MRC2,TBC1D1,DHCR24,LRRC49,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,PRKG1,SREBF1,CPXM2,FAM155A,COL9A2,GPR161,BOD1,PTCH2,SLC36A1,VLDLR,DCHS1,PACSIN3,CDC42BPA,PLEKHH2,CECR2,THBS4,C1orf21,LRRIQ3,MPP2,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,TCTN2,ST14,CCDC110,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,POU5F1B,ALDOC,PDE4D,GATM,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,ATF3,PYGO1,ATP10D,C9orf116,TDO2,CCNA1,COBL,STON2,MID1,HACE1,MYO1D,PRSS35,KIF5C,NDFIP2,LRRC55,IRX5,AFF2,GPR155,DYNC2H1,ERRFI1,TBC1D9,TMC7,VAV3,SLC40A1,ALDH2,ARHGEF28,PXN,SH3BP2,PTPN13,ZDHHC15,GPR137C,HOXA1,TERT,PLXDC2,MCC,SVIL,CERS1,UGT8,PTPN21,SLC2A13,HMCN1,CHST10,ADPRHL1,LGI2,EPCAM,PPM1E,SIPA1L2,ABI3BP,CTTN,MYRIP,PDGFRB,CYP1B1,LAMP3,TNK2,SKAP2,JPH1,TMEM47,SGK2,GSN,GPRC5B,CCDC169,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,FBXO4,CHSY1,FAM81A,SPINK5,PCDHB14,ZNF354A,SLC30A4,EEF2,LIMCH1,RNF148,LRP3,CAND2,SNX7,CDH26,PCDH10,PODXL2,SLITRK2,SDC3,PLAGL1,KIAA0355,NCR3LG1,FAT1,SH3BP4,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,XKR4,DMXL2,ARHGAP22,HECW2,COL18A1,CANX,PIBF1,SCIN,PDZD8,PPFIBP1,KAZN,C12orf60,ACVR2A,PROS1,TMEM120B,NTNG1,SEMA6C,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,MVD,TCEAL3,AMIGO1,CENPV,BATF3,BCL11A,ARMC4,MAGEA12,ZNF93,KPNA3,TRIM34,TMPRSS9,RGS10,RNF130,MAST1,ENO2,ARHGEF11,TSPAN15,SSX1,COL4A5,FAM117B,FAM174B,SEL1L3,BMP6,SYDE2,RAB11FIP5,FSD1,SCN1B,PRKCD,STC2,MARCH3,AFAP1L2,CARD6,USP2,CRIM1,GALNT14,TLR6,NAALADL2,LEPR,DPY19L2,EDA,ACER2,RNF157,NPHP1,ABCG1,PDE1B,FLVCR2,PRSS12,LSM11,STAT5B,DOCK3,NOS1AP,EYA4,EPDR1,PCDH7,BAG3,TGFBR3,PMAIP1,DNAH6,TSHR,KLHL29,NKX2-1,RWDD2A,SMAD9,TGFA,WLS,F12,CA13,MEF2C,CARS,LATS2,STOX2,TTC30B,SYCP2,BNIP1,KIAA1671,FAM189A1,CACNB2,ZIC5,LOXL4,ST8SIA1,TSPAN9,STXBP1,GLIS1,AGL,FMNL2,CHRM3,FADS1,PNP,SLC37A1,MYO10,STAT4,SMARCD3,RYR2,C1R,PLS1,TAF4B,MBNL2,DHX32,TMCO3,ADAMTS3,EMILIN2,INHBE,CDH17,SPRED3,TRPC3,ZNF516,TMSB15A,GALNT6,C4A,FAM131C,GALNT12,MYO1B,BEGAIN,LRRCC1,PKP2,NRXN1,COLEC10,TXNRD3,EPB41L3,GPRIN1,KMO,COL25A1,SYNGR3,JAKMIP3,FAM155B,SCN3A,DOCK8,PERP,DZANK1,SSH3,GARS,KCNH5,NKX3-2,NPM3,RAB38,TTC28,FGFR1,IRS2,GYPC,PLEKHG1,INPP4B,PLD5,KLHL31,TMEM132C,FARP1,ROBO2,IPO5,NKAIN2,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,GAS2L3,NPTXR,MYO6,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,SNTB1,HEG1,TRIB3,PLPPR2,GNAO1,AKT3,OSBPL5,SLCO5A1,HK1,DOCK6,BTRC,TPT1,NBPF4,TRIM2,SYT12,FHDC1,LILRB1,ASS1,NOVA1,NUP62CL,ANKRD42,KCNAB1,HPS1,LIN7A,COL19A1,KIAA1614,TLN2,TLR4,ETV1,NEB,ITGB7,GCNT2,SLC3A2,ABCC4,GDPD1,TCERG1L,BATF,TSKU,INHBC,MAP2,CCDC146,TECPR2,TNFRSF1A,TIGD4,PIK3C2B,MLLT3,CHMP4C,PRKAA2,UBASH3B,RASL11B,SETBP1,MLC1,HSPA12B,KIAA1958,IGF1R,SEMA4F,GATA2,BCHE,ABCA5,SAMD11,FBXL2,SLCO4C1,CHSY3,FGFR4,PAK1,UNC5C,MID2,RNF170,SLC27A2,HOMER2,SPATA13,TCEA3,TMTC4,WDR25,PPFIA4,PDE8A,MAPKAPK2,ATPAF2,HEYL,AVPI1,CFH,XYLT1,OR51B4,ZNF83,LPIN3,SEZ6L2,PCLO,LHX6,ZDHHC6,MYO3B,SCN2A,CTH,TMEM67,C4BPB,SMAD3,RANBP2,NRG3,ANKRD31,GBP1,PTK7,KCNG1,ABI3,ITGA2,TTC39A,CNTN1,MAN2B2,COL9A3,IL32,APBB1,TECPR1,MAP1A,FUT9,RASD2,PRICKLE2,SH3PXD2B,PCK2,SLC45A3,KIAA1211,DLGAP1,MICAL2,FNDC3A,TGDS,FAT4,DLG2,RPL4,THAP10,TBC1D4,FILIP1,CGN,MYCBP2,TCP11L2,TTC39B,SIDT1,DUSP8,ATP8A1,PPFIBP2,GATA3,ENAH,DACH2,AARS,STK24,MOK,CFHR1,SLC16A2,CHRDL1,ATRNL1,GSTM3,BEND4,VWA5A,MAGEA6,PLTP,TBC1D8,EML6,KLHL4,DNAJC6,DEPTOR,MEF2B,TNS1,ACVR2B,ARHGEF26,GPC6,AHRR,NCKAP1L,RASGRF2,PLK2,SEMA3C,UNC5B,LZTS1,INPPL1,EHHADH,CELSR1,ALOX5AP,ZHX3,PTPRD,SCN8A,GTF2IRD1,WDFY4,TNFRSF10C,DYNC1I1,ADSSL1,MECOM,MCOLN2,GBGT1,NAV1,CNTN4,KIAA1257,PIK3AP1,VWDE,PRELID1,RUNDC3B,MPDZ,RIMS2,IGSF3,EPB41L5,QSOX1,TBC1D8B,COL4A4,TTYH2,TTC30A,CCDC85A,C4orf19,PLCB1,DAGLA,PMEPA1,IQSEC2,AMPD1,FRMPD3,TBKBP1,PCSK1N,AMOTL1,RASAL2,ZNF311,OTX1,CHUK,SPATS2L,NUDT12,ZNF827,TMEM53,NAP1L3,SERPINH1,VNN2,TMEM43,SOX21,PRKCQ,TBC1D16,DCBLD2,ZNF396,PRKCB,GRB10,HS3ST3B1,ATG5,CTTNBP2,NR3C2,THOC3,DENND5B,WASF3,MXI1,ANKRD13D,GABRR2,GDPD5,NEDD4,RALGAPA2,GFI1,SPRY2,PFKFB4,ARAP2,SYNPO2,CACNA1E,CTTNBP2NL,GUCY1A2,SKAP1,ZIC1,GPLD1,CEBPB,FGR,OR2T33,NUTM2A,PGM2L1,MYOM2,GRIN2D,OCLN,NUDT17,ATP1A3,EXPH5,MVK,HEBP1,KIF5A,TNFAIP8L2,ANKRD18A,ABAT,RBM11,ABHD4,FAM27C,SLCO3A1,KREMEN1,QPRT,FKBP11,ARHGEF10L,RTN1,AKAP7,POF1B,SLC2A12,PCOLCE2,OR2W3,PTPRE,SLIT2,RASGRP1,ATL1,CAPN5,ZNF565,ROR1,EML1,TMEM132B,NCAM2,ITGBL1,BCL11B,UST,FN1,SEC24D,JDP2,CYP4V2,LAMC3,PHGDH,OTUD1,EBF4,NCEH1,NOS3,ANKRD20A2,RAX,GPR176,SH2D2A,PARD3B,EDEM3,WWC1,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,FCHO2,RAI14,HK2,CXCR5,EML5,NEK10,ZSWIM5,CELSR3,PLEKHA5,BCL6B,DOCK2,SP8,ZSCAN5A,COL22A1,UNC13B,SETDB2,RPS6KL1,ZNF521,MAP7,GULP1,POU2F2,MET,WWC2,HSPA2,DPP10,SUSD3,FER,PHLDB2,DOCK5,TTLL7,WARS,LMLN,BACH2,CYP2U1,DISP1,LIFR,PSPH,OR51B5,TNIK,CLGN,REL,LRP4,NSUN6,CLSTN2,GTSF1,DSG2,KIAA0319,TRIM3,DHRS12,IQGAP3,ESRRG,NR4A1,GRID1,OGDHL,PRRG1,MEI1,PHACTR2,AGAP2,MARS,ZFPM2,RERE,MAP1B,ADAMTS17,MYADM,NACC2,MAP2K6,THSD7B,KIAA0513,KIF21A,MMP16,SNPH,STOM |
| 7.956e-03 | -4.83 | FERM_2 | interpro domains | IPR035963 | 50 | 11 | 18492 | 1811 |
FRMPD3,EPB41L5,EPB41L3,PLEKHH2,FARP1,MYO10,PTPN13,PTPN21,FERMT2,TLN2,FRMD5 |
| 7.964e-03 | -4.83 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication | molecular function | GO:0086083 | 5 | 3 | 17224 | 1680 |
PKP2,DSP,DSG2 |
| 7.978e-03 | -4.83 | growth factor binding | molecular function | GO:0019838 | 131 | 22 | 17224 | 1680 |
FGFR4,SCN5A,ACVR1,TRIM16,IGFBP6,BMPR2,CRIM1,WISP3,ACVR1C,ITGA6,NTRK3,ACVR2B,FGFR1,TGFBR3,IGF1R,ITGB3,ACVR2A,NRP1,LIFR,PDGFRB,PCSK6,IGFBP3 |
| 7.993e-03 | -4.83 | eye | COSMIC cancer mutations | eye | 619 | 79 | 17385 | 1698 |
CGN,EML5,AMOTL1,PAGE1,PDE1B,ZNF311,MYO1B,FHDC1,HECW2,PKP2,NPM1,CEBPA,NTRK3,GRK6,DOCK3,SNX9,RBM11,PCLO,DACH2,HMCN1,EPCAM,EPB41L3,MET,VWA5A,CPE,TSHR,KIAA1549,NEB,TNK2,TMEM67,CD55,EVL,SESN2,CAP2,SHANK2,PREX1,TCEAL3,PLEKHA1,PYGO1,SESN1,TTC28,CA13,FGFR1,DCBLD2,PLK2,PTK7,GBP1,ITGA2,BMP1,BBC3,GRB10,CTNND2,CD276,SFXN3,MLC1,TTC30B,GRPEL2,ABCA5,SREBF1,ACTA2,IQGAP3,SNX7,CHSY3,CACNA1E,OBSCN,PRICKLE1,SHISA2,C1R,SDK1,EXOG,PTPRC,FAT4,TERT,PRCP,THSD7B,TUFT1,MYOM2,ACSM3,TLL2 |
| 7.999e-03 | -4.83 | TMEM132D_N | pfam domains | PF15705 | 5 | 3 | 17054 | 1666 |
TMEM132B,TMEM132C,TMEM132E |
| 7.999e-03 | -4.83 | PP-binding | pfam domains | PF00550 | 5 | 3 | 17054 | 1666 |
ALDH1L2,ALDH1L1,FASN |
| 7.999e-03 | -4.83 | Mtc | pfam domains | PF03820 | 5 | 3 | 17054 | 1666 |
SFXN1,SFXN3,SFXN4 |
| 7.999e-03 | -4.83 | HR1 | pfam domains | PF02185 | 5 | 3 | 17054 | 1666 |
RHPN2,PKN1,PKN3 |
| 7.999e-03 | -4.83 | Aminotran_3 | pfam domains | PF00202 | 5 | 3 | 17054 | 1666 |
PHYKPL,ABAT,ETNPPL |
| 7.999e-03 | -4.83 | WHEP-TRS | pfam domains | PF00458 | 5 | 3 | 17054 | 1666 |
MARS,GARS,WARS |
| 7.999e-03 | -4.83 | TMEM132 | pfam domains | PF16070 | 5 | 3 | 17054 | 1666 |
TMEM132B,TMEM132C,TMEM132E |
| 7.999e-03 | -4.83 | TMEM132D_C | pfam domains | PF15706 | 5 | 3 | 17054 | 1666 |
TMEM132B,TMEM132C,TMEM132E |
| 8.015e-03 | -4.83 | soft_tissue-fibrous_tissue_and_uncertain_origin-granular_cell_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-granular_cell_tumour | 71 | 14 | 17385 | 1698 |
GPR176,ATL1,TERT,MYO10,FAT1,ADCY1,HECW2,NKAIN2,PJA1,TCERG1L,XKR4,HMCN1,PNMA2,HEG1 |
| 8.015e-03 | -4.83 | granular_cell_tumour | COSMIC cancer mutations | granular_cell_tumour | 71 | 14 | 17385 | 1698 |
GPR176,ATL1,TERT,MYO10,FAT1,ADCY1,HECW2,NKAIN2,PJA1,TCERG1L,XKR4,HMCN1,PNMA2,HEG1 |
| 8.015e-03 | -4.83 | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | 85 | 16 | 17377 | 1707 |
TTC39B,IGF1R,BMPR2,TMEM65,WLS,STAT4,MYC,ITGA6,XBP1,FAM107B,INPP5F,NRP1,IKZF2,ATP10D,SMPDL3A,RRAGD |
| 8.021e-03 | -4.83 | RAPGEF2 (Rap guanine nucleotide exchange factor 2) | protein interactions | 9693 | 62 | 13 | 17029 | 1718 |
EPB41L5,PTPN13,KIF5A,YAP1,TJP1,MAGI2,CTTNBP2,HMCN1,MAGI3,SP140L,BTRC,NEDD4,STOM |
| 8.021e-03 | -4.83 | WWC1 (WW and C2 domain containing 1) | protein interactions | 23286 | 62 | 13 | 17029 | 1718 |
EPB41L3,LATS2,TNIK,AMOTL1,CPVL,PTPN21,KIAA0513,FEZ1,MPDZ,WWC2,PRKCA,BTRC,PATJ |
| 8.035e-03 | -4.82 | skeletal muscle organ development | biological process | GO:0060538 | 133 | 22 | 17256 | 1658 |
BVES,ASS1,ATF3,DNER,MYORG,SKI,FOXP2,MSC,HLF,EOMES,RIPOR2,EEF2,POPDC3,KCNAB1,HEYL,COL19A1,SVIL,KLF5,MYH15,MYOM2,DISP1,MEF2C |
| 8.052e-03 | -4.82 | LIN7A (lin-7 homolog A, crumbs cell polarity complex component) | protein interactions | 8825 | 36 | 9 | 17029 | 1718 |
KCNJ4,MPP7,MPP2,DLG2,MPDZ,GUCY1A2,PXDC1,BAIAP2,PATJ |
| 8.052e-03 | -4.82 | NEXN (nexilin F-actin binding protein) | protein interactions | 91624 | 36 | 9 | 17029 | 1718 |
DBN1,GSN,MYO1D,LGR4,CPVL,TES,MYO1B,ACTA2,PPP1R9A |
| 8.057e-03 | -4.82 | WHEP-TRS_dom | interpro domains | IPR000738 | 5 | 3 | 18492 | 1811 |
MARS,GARS,WARS |
| 8.057e-03 | -4.82 | Mtc | interpro domains | IPR004686 | 5 | 3 | 18492 | 1811 |
SFXN1,SFXN3,SFXN4 |
| 8.057e-03 | -4.82 | TMEM132_M | interpro domains | IPR031437 | 5 | 3 | 18492 | 1811 |
TMEM132B,TMEM132C,TMEM132E |
| 8.057e-03 | -4.82 | TMEM132_C | interpro domains | IPR031436 | 5 | 3 | 18492 | 1811 |
TMEM132B,TMEM132C,TMEM132E |
| 8.057e-03 | -4.82 | Aminotrans_3 | interpro domains | IPR005814 | 5 | 3 | 18492 | 1811 |
PHYKPL,ABAT,ETNPPL |
| 8.057e-03 | -4.82 | BEX | interpro domains | IPR007623 | 5 | 3 | 18492 | 1811 |
BEX4,BEX3,BEX2 |
| 8.057e-03 | -4.82 | TMEM132 | interpro domains | IPR026307 | 5 | 3 | 18492 | 1811 |
TMEM132B,TMEM132C,TMEM132E |
| 8.057e-03 | -4.82 | TMEM132_N | interpro domains | IPR031435 | 5 | 3 | 18492 | 1811 |
TMEM132B,TMEM132C,TMEM132E |
| 8.057e-03 | -4.82 | GST_mu | interpro domains | IPR003081 | 5 | 3 | 18492 | 1811 |
GSTM3,GSTM2,GSTM4 |
| 8.057e-03 | -4.82 | ACP-like_sf | interpro domains | IPR036736 | 5 | 3 | 18492 | 1811 |
ALDH1L2,ALDH1L1,FASN |
| 8.057e-03 | -4.82 | PP-bd_ACP | interpro domains | IPR009081 | 5 | 3 | 18492 | 1811 |
ALDH1L2,ALDH1L1,FASN |
| 8.081e-03 | -4.82 | OHGUCHI_LIVER_HNF4A_TARGETS_DN | MSigDB lists | OHGUCHI_LIVER_HNF4A_TARGETS_DN | 138 | 23 | 17377 | 1707 |
TMC7,B3GALT1,NECAB1,HEBP1,GJB2,ELOVL3,CYP4V2,ABAT,F12,RARRES2,QPRT,KCNN2,AADAT,SOAT2,KMO,CFHR1,MFSD2A,FAM107B,MPDZ,LIFR,IL1RAP,SLC45A3,PERP |
| 8.085e-03 | -4.82 | negative regulation of protein polymerization | biological process | GO:0032272 | 65 | 13 | 17256 | 1658 |
TUBB4A,GSN,MYADM,TMSB15A,PRKCD,EPS8,ADD2,TMOD2,PFN2,SLIT2,FHOD3,SCIN,SNCA |
| 8.096e-03 | -4.82 | MODULE_18 | MSigDB lists | MODULE_18 | 439 | 59 | 17377 | 1707 |
TYRO3,COL9A3,GNG12,TRIM2,FN1,TRIM16,ITGA6,IPO5,EPS8,ADD2,ZIC2,NHP2,RAC3,PHLDA2,GAS1,MTUS1,DDIT4,EPB41L3,FKBP9,ASNS,SLC7A11,MYC,TFAP2A,SMTN,GULP1,SERPINH1,MOXD1,GPR161,IGSF3,PRAME,MSX1,PXN,CRIM1,MYO10,PFKFB2,CAP2,FHL2,KCND3,SMPDL3B,HEG1,HTR7,SMAD3,INHBC,RND3,PLOD2,EIF4EBP1,FAT1,PLK2,LAMB1,WWTR1,SLC7A5,BMP1,SEMA3C,PAX9,SLC1A5,TPM1,CDH2,MME,SLC43A1 |
| 8.097e-03 | -4.82 | positive regulation of stress-activated MAPK cascade | biological process | GO:0032874 | 149 | 24 | 17256 | 1658 |
PAK1,TNIK,EDA2R,FZD4,FZD8,PKN1,PLCB1,TPD52L1,TLR6,TNFRSF19,DKK1,TLR3,ERN1,MAP3K21,DUSP19,INAVA,DAB2IP,SEMA3A,TNFRSF11A,SYK,MID1,MAP3K20,RASGRP1,HMGCR |
| 8.127e-03 | -4.81 | KERLEY_RESPONSE_TO_CISPLATIN_DN | MSigDB lists | KERLEY_RESPONSE_TO_CISPLATIN_DN | 5 | 3 | 17377 | 1707 |
HMGCS1,MYC,CYP26A1 |
| 8.127e-03 | -4.81 | JONES_TCOF1_TARGETS | MSigDB lists | JONES_TCOF1_TARGETS | 5 | 3 | 17377 | 1707 |
CCNG1,PMAIP1,PERP |
| 8.130e-03 | -4.81 | BURTON_ADIPOGENESIS_PEAK_AT_2HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_2HR | 50 | 11 | 17377 | 1707 |
ID3,BAG3,CDR2L,ID1,NR4A1,MYC,HK2,SEMA3C,ERRFI1,CEBPD,DUSP1 |
| 8.130e-03 | -4.81 | chr8q21 | MSigDB lists | chr8q21 | 50 | 11 | 17377 | 1707 |
NECAB1,HNF4G,JPH1,LRRCC1,ZNF704,MMP16,CA13,PKIA,CRISPLD1,CHMP4C,HEY1 |
| 8.148e-03 | -4.81 | GSTRNSFRASEM | prints domains | PR01267 | 5 | 3 | 4652 | 458 |
GSTM3,GSTM2,GSTM4 |
| 8.151e-03 | -4.81 | SH2 | prosite domains | PS50001 | 107 | 20 | 12060 | 1278 |
RIN2,FER,VAV3,SH3BP2,INPPL1,SH2D2A,GRB14,PTPN6,STAT4,TNS1,STAT5B,LCP2,FRK,CHN1,CHN2,FGR,SHF,GRB10,SYK,FES |
| 8.154e-03 | -4.81 | GO_MAMMARY_GLAND_DEVELOPMENT | MSigDB lists | GO_MAMMARY_GLAND_DEVELOPMENT | 115 | 20 | 17377 | 1707 |
MSX1,KDM5B,CSN2,FASN,STAT5B,DDR1,MGMT,IRS2,CEBPB,NRG3,ATP7B,CSF1,ITGA2,HK2,PAM,OXTR,BMP4,HOXB9,TNFRSF11A,BTRC |
| 8.156e-03 | -4.81 | proteoglycan biosynthetic process | biological process | GO:0030166 | 58 | 12 | 17256 | 1658 |
UST,CHSY3,BMPR2,XYLT1,HS3ST5,DSEL,PXYLP1,CHSY1,HS3ST3B1,BCAN,GLCE,HS6ST3 |
| 8.156e-03 | -4.81 | aspartate family amino acid metabolic process | biological process | GO:0009066 | 58 | 12 | 17256 | 1658 |
NMNAT3,ASNS,HYKK,AADAT,PLOD2,AASS,GCAT,ASS1,PHYKPL,PHGDH,ADSSL1,CTH |
| 8.179e-03 | -4.81 | JUNB (JunB proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 3726 | 69 | 14 | 17029 | 1718 |
SMAD3,BDNF,ATF4,MAP2,JDP2,BCL6,NFE2L1,NPM1,ATF3,CREB5,BATF,PKIA,DDIT3,BATF3 |
| 8.192e-03 | -4.80 | CAGCTTT,MIR-320 | MSigDB lists | CAGCTTT,MIR-320 | 243 | 36 | 17377 | 1707 |
MXI1,RHOBTB1,PLAG1,ABHD13,ENAH,FAM117B,CREB5,DNER,EYA4,HECTD2,ARHGAP44,IGF1R,FLRT3,KCNS3,DBN1,MN1,FOXN3,CACNA1E,ESRRG,ARID5B,SATB2,TMEM47,PALLD,CPEB1,NEGR1,NAP1L5,ICA1,SH3RF1,PLK2,KLF5,BMPR1A,PPARGC1A,NRP1,CDH2,MMP16,MLLT3 |
| 8.192e-03 | -4.80 | GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 243 | 36 | 17377 | 1707 |
LATS2,DUSP8,UBASH3B,DNAJC3,NPM1,CEBPA,PKN1,PPM1E,IGF1R,ZFYVE28,FLRT3,PRKCD,LRP6,DAB2IP,ERRFI1,SPRY2,DUSP1,HMGCR,MSTN,PTPN6,DEPTOR,DUSP9,PRKAR2B,CAMK2N1,IRS2,PTPRC,TRIB3,RANBP2,PTPRJ,WWTR1,DUSP19,BMP4,SMYD3,TESC,PKIA,SFN |
| 8.196e-03 | -4.80 | NAKAMURA_ADIPOGENESIS_LATE_DN | MSigDB lists | NAKAMURA_ADIPOGENESIS_LATE_DN | 37 | 9 | 17377 | 1707 |
SMAD3,COL9A3,ABI3BP,SLC7A5,RAI14,TMEM47,TPM1,LRP3,IGFBP3 |
| 8.196e-03 | -4.80 | GNF2_TPT1 | MSigDB lists | GNF2_TPT1 | 37 | 9 | 17377 | 1707 |
RPS20,RPS12,RPL12,RPS11,RPL13A,RPS23,RPL21,TPT1,RPS13 |
| 8.196e-03 | -4.80 | GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION | 37 | 9 | 17377 | 1707 |
PTPRC,IRS2,VAV3,NCKAP1L,TNFSF13B,BCL6,CD40,TLR4,MEF2C |
| 8.197e-03 | -4.80 | GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | MSigDB lists | GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | 448 | 60 | 17377 | 1707 |
TNIK,PLSCR4,FGF13,TSPAN15,PKP2,GAS6,P2RY1,PRKCA,SNX9,TSPAN17,EPB41L3,BNIP1,SEC16B,BHLHA15,CACNB2,EHD3,REEP1,RAP2A,RAB26,ZDHHC23,MAP7,LRP6,PRKG2,LIN7A,TMED9,DYNC2H1,COG3,PACSIN1,STXBP1,SNX10,ZNF385A,KCNB2,DPP10,ATL1,KCNIP3,TMEM43,RAPGEF2,ANK2,LRRK2,PACSIN3,ATP1B1,RAB38,SKAP1,BAIAP2,RANBP2,ARHGAP21,VPS37D,MYADM,FAT4,FCHO2,PRKCB,TNFRSF1A,AHNAK2,RAB31,FNBP1L,CDH2,TESC,RAB30,CHMP4C,HACE1 |
| 8.210e-03 | -4.80 | DBL_dom_sf | interpro domains | IPR035899 | 71 | 14 | 18492 | 1811 |
ARHGEF10L,VAV3,ARHGEF28,FARP1,ARHGEF11,RASGRF2,MCF2L2,MCF2L,PREX1,SPATA13,PLEKHG1,OBSCN,TIAM2,ARHGEF26 |
| 8.236e-03 | -4.80 | ZU5 | prosite domains | PS51145 | 13 | 5 | 12060 | 1278 |
UNC5C,TJP1,UNC5B,ANK2,SH3BP4 |
| 8.254e-03 | -4.80 | GO_RUFFLE_MEMBRANE | MSigDB lists | GO_RUFFLE_MEMBRANE | 78 | 15 | 17377 | 1707 |
EPB41L5,PAK1,FGR,PTPRJ,ITGB3,EPS8,SPATA13,WWC1,SPRY4,PLEKHA1,PACSIN1,MYO6,TPM1,SPRY2,TESC |
| 8.259e-03 | -4.80 | MODULE_5 | MSigDB lists | MODULE_5 | 422 | 57 | 17377 | 1707 |
ACSL1,ID1,ALOX5AP,IL32,FN1,IGFBP6,ITGA6,BLVRB,MYO1B,LDLR,SELL,IL13RA1,LCP2,CD53,F3,MTUS1,HOPX,EPCAM,EPB41L3,TYMP,ABLIM1,TGFBR3,MSMO1,GATA2,SERPINH1,SLIT2,PDGFRB,LAMP3,NKX2-1,CYP1B1,FGFR4,FADS1,QSOX1,CD55,COL6A2,PNP,CRIM1,NR4A1,SLC39A8,CALCRL,ATP11A,RARRES2,FGFR1,HEG1,PTPRC,CD37,FGR,INSIG1,GBP1,WFS1,P4HA2,WWTR1,RAB31,HPGD,MAOA,PIK3C2B,TPM1 |
| 8.259e-03 | -4.80 | TGCACTT,MIR-519C,MIR-519B,MIR-519A | MSigDB lists | TGCACTT,MIR-519C,MIR-519B,MIR-519A | 422 | 57 | 17377 | 1707 |
NBL1,ACVR1,DUSP8,BMPR2,ARHGEF11,KIF5A,RASL11B,RASD1,MAPK4,CREB5,FAM13A,TNKS1BP1,FOXG1,IKZF2,PFN2,ZFYVE9,FSTL5,CCNJ,SKI,RTN1,KCNN2,TRIM3,MAP7,NBEA,COL19A1,KLF9,TBC1D9,TSPAN9,MYT1,SLC40A1,COL4A3,SOX21,SHANK2,VLDLR,RAPGEF4,SYBU,PREX1,NFIA,ZFPM2,MFSD6,PLCB1,MAP1B,DCBLD2,ZNF711,KLF12,KPNA3,FCHO2,AKT3,ZNF704,KIAA0513,SFMBT1,PGM2L1,SPRY4,FNBP1L,NEUROG2,FOXA1,PKIA |
| 8.278e-03 | -4.79 | TSP1_rpt_sf | interpro domains | IPR036383 | 64 | 13 | 18492 | 1811 |
ADAMTS17,UNC5C,ADGRB3,WISP3,ADAMTS3,ISM1,THSD4,THSD7B,ADAMTS6,UNC5B,THSD1,HMCN1,ADGRB2 |
| 8.284e-03 | -4.79 | large_intestine-rectum | COSMIC cancer mutations | large_intestine-rectum | 584 | 75 | 17385 | 1698 |
EXPH5,AASS,PPFIBP2,COL18A1,DOCK2,HMCN1,ZSCAN5A,TRPS1,MYO3B,TRPC1,PCOLCE2,DNAH5,FER,TMEM67,COL6A2,ADM2,TDRD3,PTPRU,KCNH5,KLHL4,SATB2,TNS1,KCND3,GPC6,TMEM132B,ARMC4,SPATA9,DSEL,PLD5,KLHL31,UNC5B,DNHD1,MLLT3,PURG,CNTN1,TMEM63C,LATS2,PCDH18,DYRK3,EHHADH,PTPRD,REL,EPS8,SLC12A6,DYNC1I1,COL27A1,MTUS1,PDE10A,DSG2,FAM107B,PRKG1,SLC6A15,STXBP1,ZNF629,SLITRK2,RAB6B,FASN,RYR2,SLITRK5,OBSCN,PRICKLE1,ST6GALNAC3,CCDC85A,BAIAP2,MAP1B,DKK1,TEX15,PCDHB7,FAT4,FBN1,LRRIQ3,DISP2,FNBP1L,MMP16,LARP1 |
| 8.289e-03 | -4.79 | pulmonary_blastoma | COSMIC cancer mutations | pulmonary_blastoma | 656 | 83 | 17385 | 1698 |
PRSS12,PLEKHA5,GALNT6,PLXNA2,ENAH,PIBF1,KREMEN1,SEMA6A,DDX60L,SLC9A7,TRPS1,CPNE2,SIPA1L2,TM9SF2,PDZD8,IKZF5,AADAT,ZFYVE28,MARVELD2,MAGEA3,MAP7,SLC2A12,CTTN,TLN2,KLHL23,PTPRU,LRRC8B,SATB2,TBC1D16,ARHGAP21,MAP2,CCNA1,DSEL,RNF130,TANC2,CTTNBP2,MAGI2,MEF2C,KCNV1,TMEM63C,MYO1D,WDR17,IL32,PTPRD,ST6GAL1,IPO5,DYNC1I1,BEX2,COL27A1,FHOD3,SYCP2,TECPR1,MAP1A,BCHE,BACE2,TSC22D1,MPDZ,SLC6A15,CADPS2,SMAD6,PRR16,ATP2B1,RIMS2,CES3,CHSY3,RIN2,DCHS1,SYBU,KIAA1324L,PPFIA4,SLITRK5,MAFB,WWC1,NSD1,FAT4,FBN1,ZNF214,FMO4,LRRIQ3,ZNF808,KIF21A,PTGES,ABCG1 |
| 8.289e-03 | -4.79 | pleura-pulmonary_blastoma | COSMIC cancer mutations | pleura-pulmonary_blastoma | 656 | 83 | 17385 | 1698 |
PRSS12,PLEKHA5,GALNT6,PLXNA2,ENAH,PIBF1,KREMEN1,SEMA6A,DDX60L,SLC9A7,TRPS1,CPNE2,SIPA1L2,TM9SF2,PDZD8,IKZF5,AADAT,ZFYVE28,MARVELD2,MAGEA3,MAP7,SLC2A12,CTTN,TLN2,KLHL23,PTPRU,LRRC8B,SATB2,TBC1D16,ARHGAP21,MAP2,CCNA1,DSEL,RNF130,TANC2,CTTNBP2,MAGI2,MEF2C,KCNV1,TMEM63C,MYO1D,WDR17,IL32,PTPRD,ST6GAL1,IPO5,DYNC1I1,BEX2,COL27A1,FHOD3,SYCP2,TECPR1,MAP1A,BCHE,BACE2,TSC22D1,MPDZ,SLC6A15,CADPS2,SMAD6,PRR16,ATP2B1,RIMS2,CES3,CHSY3,RIN2,DCHS1,SYBU,KIAA1324L,PPFIA4,SLITRK5,MAFB,WWC1,NSD1,FAT4,FBN1,ZNF214,FMO4,LRRIQ3,ZNF808,KIF21A,PTGES,ABCG1 |
| 8.295e-03 | -4.79 | GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | 194 | 30 | 17377 | 1707 |
CREB3L2,BTC,RAB3B,UGT8,SKAP2,BVES,HEBP1,HOMER2,FHDC1,PRSS35,ZNF605,AMDHD1,SLC22A17,SH3GL2,SLC30A4,FBN1,AKT3,RBPMS2,THBS4,MATN2,POF1B,ACVR2A,GRIP1,CPXM2,PIP5KL1,PCOLCE2,CTTN,SEMA3A,PTGES,IL1RAP |
| 8.295e-03 | -4.79 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_UP | 194 | 30 | 17377 | 1707 |
GPT2,NBL1,ACVR1,MRC2,CLYBL,SYT12,GJB2,ARID5B,PHACTR2,SYNJ2BP,PRDM1,CTTNBP2NL,ATP1B1,BCAN,DDR1,CPEB1,GRPEL2,BAIAP2,FKBP11,QPRT,PCDH7,PRKCB,SAMD11,MAP7,PTPRS,ERRFI1,PTPRE,AGL,TC2N,B4GALT7 |
| 8.295e-03 | -4.79 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | 194 | 30 | 17377 | 1707 |
VAV3,ARAP2,CSN2,CRIM1,RHOD,ARL15,FOXN3,LDLR,LRMP,SCD,LCP2,SNX9,SCIN,CYP51A1,EOMES,PLAGL1,GAS2L3,STARD4,NCOA7,SQLE,PTPRS,ADCY6,LIN7A,TSPAN13,IPCEF1,PACSIN1,NRP1,TBC1D4,RASGRP1,RNF152 |
| 8.295e-03 | -4.79 | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN | MSigDB lists | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN | 194 | 30 | 17377 | 1707 |
PLA2G4A,RHOQ,ACSL1,ID1,RNF145,SCAMP1,IL15,AASS,TES,SPATA13,MSR1,PLEKHA1,FNDC3A,LCP2,CD40,HERPUD1,CD53,CEBPB,MCOLN2,MYADM,CA2,SLC30A4,KPNA3,MYC,HK2,ERRFI1,SNX10,PTGES,CEBPD,DUSP1 |
| 8.301e-03 | -4.79 | GSE15659_TREG_VS_TCONV_DN | MSigDB lists | GSE15659_TREG_VS_TCONV_DN | 154 | 25 | 17377 | 1707 |
C2orf88,ERGIC1,NECAB2,UROS,ELOVL7,EFHC2,PANK1,GAS6,FOXG1,ABHD6,ZNF618,NUMBL,FRY,WIPF3,GHR,THSD7B,MYO3B,ACVR2A,PDE4D,RAB27B,TC2N,MMP16,ATP6AP1L,C8orf48,CACNA2D1 |
| 8.338e-03 | -4.79 | chest | COSMIC cancer mutations | chest | 147 | 24 | 17385 | 1698 |
EFNB2,FER,TMEM63C,PTPRD,DCC,PTPN13,PTPN21,TNS1,EPHB1,KHDRBS2,FGFR1,PTPRC,TMEM132B,PTPRJ,TERT,ADAMTS3,PTK7,PPFIBP1,PTPRS,PTPRN2,ACVR2A,MET,PTPRE,CHRM3 |
| 8.345e-03 | -4.79 | GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN | MSigDB lists | GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_DN | 186 | 29 | 17377 | 1707 |
DLGAP1,TYRO3,MTG1,NBL1,ID1,FGF13,WISP3,PFKFB2,KLHL23,ADCY1,TTYH2,CR2,C1R,NTRK3,APBA1,FOXG1,FAM131B,ZNF711,MMP15,SPEG,SOAT2,SCN1B,NXPH4,HRK,LIMCH1,NKX2-8,SNAI2,CNTN1,LAMP3 |
| 8.345e-03 | -4.79 | GSE30083_SP3_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP3_VS_SP4_THYMOCYTE_DN | 186 | 29 | 17377 | 1707 |
CXCR5,RIN2,RHOQ,EVL,TTC39B,SIDT1,SEC24D,RNF144A,UBASH3B,STAT4,CYP4V2,LITAF,NTRK3,IL18R1,ATP10D,HOPX,EOMES,KCNN2,HPSE,MARVELD2,PRKCD,SGK1,HS3ST3B1,CERS4,GEM,PLTP,SNX10,SPRY2,SMPDL3A |
| 8.345e-03 | -4.79 | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN | MSigDB lists | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN | 186 | 29 | 17377 | 1707 |
SERINC5,LATS2,CARD6,PNRC1,RNF145,ATP8A1,TGFA,SPATA6,RASA3,CR2,C20orf194,SLC12A6,SATB1,CACNB4,SLC46A3,PGAP1,CD53,GSN,OTUD1,RALGPS2,SEC16B,BACH2,FRY,HPSE,GNB4,BCL6,FAM84B,CPE,HSPA2 |
| 8.345e-03 | -4.79 | GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_DN | 186 | 29 | 17377 | 1707 |
RGS16,GCNT2,PRSS12,RBFOX2,MYO1B,CHRNA6,PKP2,KCTD12,GSTO1,ABAT,F3,DCBLD2,DKK1,EPB41L3,ID3,PLAGL1,CA2,ATP7B,SMTN,BCL6,PTPRN2,ATRNL1,RPS12,EPHB6,ZNF460,SHOX2,MID1,ATP1A3,FZD1 |
| 8.345e-03 | -4.79 | GSE15767_MED_VS_SCS_MAC_LN_UP | MSigDB lists | GSE15767_MED_VS_SCS_MAC_LN_UP | 186 | 29 | 17377 | 1707 |
SUSD3,MAN2B2,ALDH2,SKAP2,DSTN,PTPN6,CD276,LRP4,MSR1,SELL,NPC2,GAS6,RAB38,APBA1,ASPH,CDS1,RAB11FIP5,EPB41L3,GSN,RNF180,TMEM150B,DOCK7,NCKAP1L,GPR160,PRKCD,RAB31,STEAP3,PROS1,TLR4 |
| 8.345e-03 | -4.79 | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN | 186 | 29 | 17377 | 1707 |
CXCR5,RIN2,GNG12,SLC3A2,EVL,PNRC1,CYP2J2,VLDLR,SELL,TJP1,SCD,PLEKHA1,CD40,RERE,RNF141,IGF1R,RALGPS2,HPS1,PLK2,RGS10,BCL6,TSC22D1,SVIL,ADCY6,PTPRS,ZBTB20,GATM,ABCG1,PCSK5 |
| 8.345e-03 | -4.79 | GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN | MSigDB lists | GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN | 186 | 29 | 17377 | 1707 |
MPZL3,MOB1B,ITPRIP,RNF144A,PSTPIP2,UBASH3B,FOXN3,EFHC2,CHSY1,TGDS,SNTB1,PRKCA,NDFIP2,GDPD5,LEPR,HOPX,HEG1,FBXO32,HMGCS1,MSMO1,GPR155,PPFIBP1,ACVR2A,PTPRN2,PDE4D,TANC2,FES,DOCK9,HMGCR |
| 8.355e-03 | -4.78 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_DN | 162 | 26 | 17377 | 1707 |
ARAP2,SYNPO2,DYRK3,RNF144A,AASS,RBFOX2,FEZ1,HERC5,BCL6B,SLC25A28,HERC6,TNFRSF19,PGAP1,SEMA6A,GAS1,OTUD1,FUT9,PMAIP1,CCDC146,TNFSF15,HS3ST3B1,CMPK2,CERS1,FBXO27,SP140L,CSRP2 |
| 8.374e-03 | -4.78 | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_CD8_TCELL_UP | 178 | 28 | 17377 | 1707 |
LATS2,EHHADH,SIDT1,MLF1,EXOC6B,ATOX1,CYP4V2,PKP2,RABAC1,COTL1,TGDS,ADSSL1,FAM174B,PFN2,DDIT4,PLS3,ENTPD1,CD37,RPS11,SLC10A7,ITGB3,SGK1,CAB39L,DSEL,CERS4,PTPRCAP,MLLT3,RASGRP1 |
| 8.374e-03 | -4.78 | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN | 178 | 28 | 17377 | 1707 |
RIN2,MOCOS,SH2D2A,NFE2L1,NRN1,ATF3,RABAC1,ITPR2,LACC1,SATB1,LEPR,DDIT4,CEBPB,MAPKAPK2,SLC7A11,P4HA2,FAM114A2,SLC7A5,SLCO5A1,GRB10,CAB39L,TMED9,PDE4D,CMPK2,MAST4,SMAD6,DDIT3,FES |
| 8.374e-03 | -4.78 | GSE3982_MAST_CELL_VS_DC_UP | MSigDB lists | GSE3982_MAST_CELL_VS_DC_UP | 178 | 28 | 17377 | 1707 |
RPL26,MEIS2,PNP,RNF144A,GABRB2,ZCCHC24,EFHC2,DEPTOR,BEGAIN,KIF21B,IL18R1,RPL34,DDIT4,ZNF711,FBN1,ABI3BP,CCNA1,STC2,TSC22D1,NBEA,GRB10,TOX,DYNC2H1,VWA5A,HOXB9,TESC,HEY1,PGBD5 |
| 8.374e-03 | -4.78 | GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_DN | 178 | 28 | 17377 | 1707 |
B9D1,PDK1,EHHADH,KLHL4,TTC30A,ZNF215,PRDM1,GUCY1A2,SMPDL3B,FKBP11,MMP15,RTN1,PPP1R26,MGAT1,ITGBL1,KAZN,GHR,ITGA2,CDH17,RCN3,GSTM3,FAM149A,TNFRSF17,TSHR,ZNF460,CTH,PCSK5,HEY1 |
| 8.378e-03 | -4.78 | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 170 | 27 | 17377 | 1707 |
MPZL3,SEMA6B,MICAL2,RGS16,ALDH2,ID1,RUNX2,KLHL13,REL,ZCCHC24,BIK,SELL,HIP1,COTL1,ATP1B1,ILDR2,GPC6,ZNF711,IL17D,PTK7,ZNF704,SVIL,RCAN3,MYRIP,ESD,TNFRSF11A,GFRA1 |
| 8.387e-03 | -4.78 | cellular response to hormone stimulus | biological process | GO:0032870 | 603 | 76 | 17256 | 1658 |
SORBS1,ACSL1,RBFOX2,ASS1,STAT5B,PLPP1,FBXO32,ASNS,TSHR,SLIT2,PRKACB,FER,NR6A1,ADCY1,YAP1,PRKAR2B,ABCC2,IRS2,ENPP1,EIF4EBP1,GNB4,ITGA2,RGS10,OXTR,TNFSF4,PPARGC1A,NR3C2,CGB2,HEY1,MEF2C,PRKAA2,GNG12,LATS2,ROBO2,ATP6V1E2,NEDD4,DDIT4,NKX6-1,HMGCS1,IGF1R,CA2,PRKCD,GHR,SREBF1,ADCY6,GRIP1,KLF9,ERRFI1,PCK2,ZFP36L2,ATP2B1,CHRM3,DUSP1,PAK1,RHOQ,PXN,MSTN,HNF4G,NR4A1,ESRRG,FHL2,MARS,PLCB1,LEPR,BAIAP2,CPEB1,GPLD1,TRIB3,PMEPA1,FBN1,XBP1,RAB31,BMP4,TBC1D4,SMYD3,ATP1A3 |
| 8.399e-03 | -4.78 | MODULE_199 | MSigDB lists | MODULE_199 | 57 | 12 | 17377 | 1707 |
FGFR4,PTK7,IL13RA1,ROR1,EPHB6,EPHB1,NRP1,MAPK10,LEPR,PDGFRB,FGFR1,F3 |
| 8.399e-03 | -4.78 | GO_MAIN_AXON | MSigDB lists | GO_MAIN_AXON | 57 | 12 | 17377 | 1707 |
DAGLA,TUBB4A,EPB41L3,MYO1D,KCNQ3,KCNAB1,ROBO2,SCN1B,SCN8A,APBB1,DLG2,SCN2A |
| 8.428e-03 | -4.78 | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN | MSigDB lists | BHATI_G2M_ARREST_BY_2METHOXYESTRADIOL_DN | 123 | 21 | 17377 | 1707 |
GPT2,RPL26,GARS,SESN2,ATF4,OGDHL,CBS,AIG1,AARS,HERPUD1,RPL34,PYCR1,ZFP62,TCF7L1,TRIB3,RPL12,PRTFDC1,EEF2,GFI1,DDIT3,CTH |
| 8.428e-03 | -4.78 | GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_LIPID_BIOSYNTHETIC_PROCESS | 123 | 21 | 17377 | 1707 |
PLA2G4A,FGFR4,PRKAA2,SORBS1,LDLR,ABHD6,PIBF1,BMP6,GPLD1,TRIB3,INSIG1,PRKCD,XBP1,SREBF1,TNFRSF1A,PPARGC1A,GFI1,DHCR7,SLC45A3,SNAI2,ABCG1 |
| 8.428e-03 | -4.78 | CCTGTGA,MIR-513 | MSigDB lists | CCTGTGA,MIR-513 | 123 | 21 | 17377 | 1707 |
ANTXR2,DNM3,EVL,PXN,BNIP3L,AGAP2,KCND3,FGFR1,BAIAP2,MTUS1,PPM1E,SEMA4F,CDC14B,RBPMS2,C1QL4,MPPED2,PGM2L1,PPARGC1A,SFN,CYP1B1,CGB2 |
| 8.429e-03 | -4.78 | Semap_dom_sf | interpro domains | IPR036352 | 31 | 8 | 18492 | 1811 |
SEMA6B,SEMA3C,MET,SEMA4F,SEMA3A,SEMA6A,SEMA6C,PLXNA2 |
| 8.429e-03 | -4.78 | Semap_dom | interpro domains | IPR001627 | 31 | 8 | 18492 | 1811 |
SEMA6B,SEMA3C,MET,SEMA4F,SEMA3A,SEMA6A,SEMA6C,PLXNA2 |
| 8.444e-03 | -4.77 | transferase activity, transferring hexosyl groups | molecular function | GO:0016758 | 212 | 32 | 17224 | 1680 |
CCDC126,UGT8,GALNT6,GALNT12,XYLT1,ALG1L,GALNT13,CHSY1,MGAT5B,GALNT1,TYMP,GBGT1,FUT9,MGAT1,AGL,GALNT18,ALG10B,B4GALT6,CHSY3,B3GALT1,GCNT2,MGAT4B,COLGALT2,GALNT17,GALNT14,B4GALNT3,DPY19L2,GALNT3,PLOD2,B3GALT2,ALG11,B4GALT7 |
| 8.457e-03 | -4.77 | FA58C_1 | prosite domains | PS01285 | 18 | 6 | 12060 | 1278 |
CPXM2,NRP1,DDR1,CNTNAP3,DCBLD1,DCBLD2 |
| 8.476e-03 | -4.77 | V$FOXO1_02 | MSigDB lists | V$FOXO1_02 | 227 | 34 | 17377 | 1707 |
PCDH18,C1QTNF3,CHCHD7,PLAG1,RASD1,FOXG1,NEDD4,DDIT4,FOXP2,FRY,SLC10A7,RASD2,TSPAN13,KLF9,ETV1,PAK1,GCNT2,MEIS2,FOXN3,SATB2,PRDM1,ROR1,HOXA1,EML1,ZNF711,INSIG1,KLF12,SH3RF1,GNAO1,PELI2,OSBPL5,MAPK10,LIFR,CACNA2D1 |
| 8.477e-03 | -4.77 | human chr10q24.2 | chromosome location | human chr10q24.2 | 32 | 7 | 26185 | 1967 |
SLC25A28,ABCC2,AVPI1,LOXL4,MORN4,HPS1,ENTPD7 |
| 8.479e-03 | -4.77 | GO_MESODERM_MORPHOGENESIS | MSigDB lists | GO_MESODERM_MORPHOGENESIS | 64 | 13 | 17377 | 1707 |
SMAD3,EPB41L5,ACVR1,EOMES,BMPR2,WLS,ITGB3,ITGA2,WNT11,BMPR1A,BMP4,SIX2,DKK1 |
| 8.482e-03 | -4.77 | regulation of protein secretion | biological process | GO:0050708 | 423 | 56 | 17256 | 1658 |
EXPH5,PRKN,FN1,C1QTNF3,STXBP5L,LGR4,TRIM16,APBB1,ARL2,LILRB1,GATA3,CHUK,ITPR2,GAS6,ABAT,NRXN1,PRKCA,BMP6,MCU,NKX6-1,RAB11FIP5,UNC13B,SREBF1,KCNS3,MARCKS,PCK2,MYRIP,TLR4,SYK,IL1RAP,RASGRP1,HMGCR,TRPM4,VEGFC,GAPDH,PFKFB2,ACVR1C,WLS,CACNA1E,SYBU,LRRK2,RAPGEF4,SNAP25,CD40,TLR6,SERGEF,GPLD1,IRS2,FGR,ICA1,GBP1,XBP1,PAM,DISP1,ATG5,TNFSF4 |
| 8.515e-03 | -4.77 | proximal promoter sequence-specific DNA binding | molecular function | GO:0000987 | 452 | 60 | 17224 | 1680 |
CREB3L2,BCL11B,KLF8,RUNX2,ZNF516,ZNF395,PLAG1,JDP2,OTX1,GATA3,STAT5B,CEBPA,ZNF219,NKX6-1,FOXP2,GRHL1,GATA2,MYC,SREBF1,TFAP2A,POU2F2,SMAD6,ETV1,CEBPD,GLI1,RAX,KCNIP3,ATF4,MEIS2,HNF4G,NR6A1,SOX21,NKX3-2,NR4A1,NFIA,LITAF,YAP1,MAFB,MEF2B,SATB2,ATF3,PRDM1,ATOH1,BATF,ZIC1,BATF3,BCL11A,CEBPB,SMAD3,NSD1,NACC2,CIART,KLF5,HOXD13,NKX2-8,NEUROG2,SMYD3,SIX2,DDIT3,MEF2C |
| 8.518e-03 | -4.77 | GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 653 | 83 | 17377 | 1707 |
ID1,DNM3,FGF13,LILRB1,ADD2,NPM1,NRXN1,PIBF1,TBC1D30,SEMA6A,PPP1R9A,SCIN,SKI,RPS6KA2,DACT1,DAB2IP,PACSIN1,HSPA2,SLIT2,SEMA6C,NKX2-1,PHLDB2,TMEM67,EVL,DCC,LRRK2,FEZ1,VIM,EML1,BCL11A,SNCA,TRIM9,GSN,CXCL10,INSIG1,EIF4EBP1,PLK2,GBP1,MAP9,SEMA3C,HGF,INPP5F,TMOD2,PPARGC1A,ATG5,NRP1,TMEFF2,MID1,SEMA6B,ROBO2,LGALS3,CKAP2,LRP4,EPS8,CHADL,OVOL2,GPSM2,PFN2,FHOD3,RPL13A,EFEMP1,SEMA4F,MAP1A,PRKCD,KIAA0319,PRELID1,ADCY6,SGK1,BNIP3,GFI1,SMAD6,SPRY2,RHOQ,RAPGEF2,PACSIN3,DKK1,PLEKHH2,MYADM,PMEPA1,BMP4,SEMA3A,TBC1D4,FOXA1 |
| 8.534e-03 | -4.76 | GO_SERINE_TYPE_CARBOXYPEPTIDASE_ACTIVITY | MSigDB lists | GO_SERINE_TYPE_CARBOXYPEPTIDASE_ACTIVITY | 14 | 5 | 17377 | 1707 |
CPXM2,PRSS16,CPVL,CPE,PRCP |
| 8.534e-03 | -4.76 | GO_POSITIVE_REGULATION_OF_B_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_B_CELL_DIFFERENTIATION | 14 | 5 | 17377 | 1707 |
STAT5B,PRDM1,NCKAP1L,SYK,XBP1 |
| 8.534e-03 | -4.76 | BOYAULT_LIVER_CANCER_SUBCLASS_G12_DN | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G12_DN | 14 | 5 | 17377 | 1707 |
HLF,FAM13A,ALDH1L1,RUNDC3B,TSKU |
| 8.534e-03 | -4.76 | GO_CELLULAR_RESPONSE_TO_ARSENIC_CONTAINING_SUBSTANCE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ARSENIC_CONTAINING_SUBSTANCE | 14 | 5 | 17377 | 1707 |
GSTO1,ATF3,ATF4,GSTO2,UROS |
| 8.534e-03 | -4.76 | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | MSigDB lists | REACTOME_REGULATION_OF_COMPLEMENT_CASCADE | 14 | 5 | 17377 | 1707 |
CD55,PROS1,CFH,C4A,C4BPB |
| 8.534e-03 | -4.76 | GO_REGULATION_OF_CAMP_DEPENDENT_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_CAMP_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 14 | 5 | 17377 | 1707 |
PRKAR2B,SESN2,RAPGEF2,ATP2B4,PKIA |
| 8.534e-03 | -4.76 | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | MSigDB lists | REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | 14 | 5 | 17377 | 1707 |
PAK1,NRP1,SEMA3A,FES,PLXNA2 |
| 8.534e-03 | -4.76 | GO_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_INSULIN_LIKE_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 14 | 5 | 17377 | 1707 |
GRB10,IGF1R,PLCB1,CRIM1,GHR |
| 8.534e-03 | -4.76 | GO_CELL_MIGRATION_INVOLVED_IN_HEART_DEVELOPMENT | MSigDB lists | GO_CELL_MIGRATION_INVOLVED_IN_HEART_DEVELOPMENT | 14 | 5 | 17377 | 1707 |
BVES,FLRT3,PDGFRB,DCHS1,SNAI2 |
| 8.534e-03 | -4.76 | GO_VOLTAGE_GATED_SODIUM_CHANNEL_COMPLEX | MSigDB lists | GO_VOLTAGE_GATED_SODIUM_CHANNEL_COMPLEX | 14 | 5 | 17377 | 1707 |
SCN5A,SCN2A,SCN1B,SCN8A,SCN3A |
| 8.534e-03 | -4.76 | GO_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | MSigDB lists | GO_MEMBRANE_DEPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 14 | 5 | 17377 | 1707 |
SCN5A,SCN1B,CACNB2,ANK2,CACNA2D1 |
| 8.534e-03 | -4.76 | LIM_MAMMARY_LUMINAL_PROGENITOR_DN | MSigDB lists | LIM_MAMMARY_LUMINAL_PROGENITOR_DN | 14 | 5 | 17377 | 1707 |
KCNIP3,TBC1D9,ASPH,EPDR1,SCARF2 |
| 8.534e-03 | -4.76 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | MSigDB lists | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | 14 | 5 | 17377 | 1707 |
DPYSL5,NRP1,SEMA3A,FES,PLXNA2 |
| 8.534e-03 | -4.76 | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC | MSigDB lists | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC | 14 | 5 | 17377 | 1707 |
SMAD3,DACH2,HEYL,MEF2C,HEY1 |
| 8.534e-03 | -4.76 | chr13q21 | MSigDB lists | chr13q21 | 14 | 5 | 17377 | 1707 |
KLF5,KCTD12,UCHL3,TBC1D4,CLN5 |
| 8.538e-03 | -4.76 | endocardial cushion development | biological process | GO:0003197 | 38 | 9 | 17256 | 1658 |
MSX1,ACVR1,BMPR2,HEYL,DCHS1,BMP4,BMPR1A,SNAI2,HEY1 |
| 8.566e-03 | -4.76 | GO_INDOLE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_INDOLE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 25 | 7 | 17377 | 1707 |
MAOA,RNF180,BTBD9,PDE1B,AADAT,KMO,TDO2 |
| 8.566e-03 | -4.76 | GNF2_CDH11 | MSigDB lists | GNF2_CDH11 | 25 | 7 | 17377 | 1707 |
FKBP9,COL6A2,FN1,SERPINH1,FBN1,LAMB1,RAI14 |
| 8.566e-03 | -4.76 | CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_UP | 25 | 7 | 17377 | 1707 |
CALCRL,HPGD,ALOX5AP,MOXD1,TDO2,KMO,GPR65 |
| 8.566e-03 | -4.76 | LEE_DOUBLE_POLAR_THYMOCYTE | MSigDB lists | LEE_DOUBLE_POLAR_THYMOCYTE | 25 | 7 | 17377 | 1707 |
EFNB2,RASD1,CYP2U1,ELOVL4,C3orf52,TBC1D19,BCL6 |
| 8.566e-03 | -4.76 | OZEN_MIR125B1_TARGETS | MSigDB lists | OZEN_MIR125B1_TARGETS | 25 | 7 | 17377 | 1707 |
SLC7A1,CGN,ABCC4,RNF144A,PLEKHA8,EIF4EBP1,KCNS3 |
| 8.566e-03 | -4.76 | MODULE_306 | MSigDB lists | MODULE_306 | 25 | 7 | 17377 | 1707 |
GAPDH,PCK2,ENO2,ENO1,ALDOC,ALDOA,ACO1 |
| 8.566e-03 | -4.76 | GO_NEGATIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TOLL_LIKE_RECEPTOR_SIGNALING_PATHWAY | 25 | 7 | 17377 | 1707 |
TYRO3,DAB2IP,TLR3,LGR4,PIK3AP1,TLR4,SMPDL3B |
| 8.566e-03 | -4.76 | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | MSigDB lists | GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN | 25 | 7 | 17377 | 1707 |
COL18A1,IL13RA1,PXN,MET,FN1,NRP1,PRKCD |
| 8.566e-03 | -4.76 | GO_REGULATION_OF_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | 25 | 7 | 17377 | 1707 |
ACVR2A,SYNJ2BP,ACVR2B,ACVR1,MAGI2,DACT1,SKI |
| 8.571e-03 | -4.76 | Cell-type Dependent Selectivity of CCK2R Signaling | WikiPathways | WP3679 | 13 | 5 | 5312 | 569 |
TRPC1,DAGLA,RYR2,PLCB1,GNAI1 |
| 8.578e-03 | -4.76 | KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM | MSigDB lists | KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM | 31 | 8 | 17377 | 1707 |
GCAT,CBS,MAOA,PHGDH,GATM,PSPH,GLDC,CTH |
| 8.578e-03 | -4.76 | GHANDHI_DIRECT_IRRADIATION_DN | MSigDB lists | GHANDHI_DIRECT_IRRADIATION_DN | 31 | 8 | 17377 | 1707 |
MN1,FZD4,PTK7,CNKSR3,SYBU,TOX,NR3C2,BCL11A |
| 8.578e-03 | -4.76 | MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS | MSigDB lists | MATTIOLI_MULTIPLE_MYELOMA_WITH_14Q32_TRANSLOCATIONS | 31 | 8 | 17377 | 1707 |
ITGB7,ABLIM1,GYPC,MAFB,PKP2,TBC1D9,FAM174B,TLR4 |
| 8.578e-03 | -4.76 | GO_CELLULAR_RESPONSE_TO_GLUCOSE_STARVATION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_GLUCOSE_STARVATION | 31 | 8 | 17377 | 1707 |
PRKAA2,ASNS,ATF4,PMAIP1,BHLHA15,VLDLR,XBP1,NUAK2 |
| 8.578e-03 | -4.76 | XK (X-linked Kx blood group) | protein interactions | 7504 | 9 | 4 | 17029 | 1718 |
CARD6,INPPL1,PRKCA,CLGN |
| 8.578e-03 | -4.76 | PIP4P2 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2) | protein interactions | 55529 | 9 | 4 | 17029 | 1718 |
GTF2IRD1,TBC1D9,GDPD5,TTC30B |
| 8.578e-03 | -4.76 | MPZL2 (myelin protein zero like 2) | protein interactions | 10205 | 9 | 4 | 17029 | 1718 |
MPZL3,ATF4,IGF1R,OCLN |
| 8.611e-03 | -4.75 | response to nutrient levels | biological process | GO:0031667 | 459 | 60 | 17256 | 1658 |
PRKAA2,PCSK1N,ACSL1,BMPR2,IL15,LDLR,SELL,ASS1,CHSY1,GAS6,ADSSL1,CYP26A1,STK24,HMGCS1,ASNS,EEF2,ZNF354A,PMAIP1,BCHE,BHLHA15,STC2,SREBF1,CADPS2,PCK2,AGL,ATP2B1,RNF152,HMGCR,FADS1,TRPM4,GDAP1,SESN2,ATF4,ACVR1C,LRRK2,NUAK2,MARS,ATF3,WNT11,CD40,SESN1,LRAT,MGMT,BAIAP2,GABARAPL1,CXCL10,GSN,PEMT,CTSV,XBP1,ITGA2,ADRB1,PIK3C2B,ATG5,PPARGC1A,TRPC3,PSPH,LARP1,DDIT3,RRAGD |
| 8.612e-03 | -4.75 | negative regulation of developmental growth | biological process | GO:0048640 | 95 | 17 | 17256 | 1658 |
PAK1,FGF13,MSTN,DCC,WWC1,SAV1,SEMA4F,STC2,ADRB1,PTPRS,SEMA3C,BMP4,NRP1,SPART,WWC2,SEMA3A,TLL2 |
| 8.612e-03 | -4.75 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | 93 | 17 | 17377 | 1707 |
PPP4R4,TRIM2,CA2,ISM1,CYP2J2,WLS,CYB5R2,ITGA2,STC2,SGK3,MPPED2,ACTA2,OXTR,ESD,AMDHD1,PERP,FHOD3 |
| 8.633e-03 | -4.75 | GSE40274_EOS_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_EOS_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 108 | 19 | 17377 | 1707 |
TCTN2,LRRC8B,SPOCD1,SOX21,PPFIBP2,ENAH,GABRR2,SLC7A2,NUDT12,TBC1D2,IL17D,TCF7L1,TDO2,PELI2,LHX6,STXBP1,SLC16A10,CHMP4C,GLI1 |
| 8.633e-03 | -4.75 | HALLMARK_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 108 | 19 | 17377 | 1707 |
CEBPB,BAG3,ASNS,ATF4,EEF2,EIF4EBP1,DNAJC3,WFS1,XBP1,STC2,ERN1,SLC7A5,NPM1,ATF3,CHAC1,NHP2,FKBP14,HERPUD1,DDIT4 |
| 8.667e-03 | -4.75 | bone development | biological process | GO:0060348 | 166 | 26 | 17256 | 1658 |
MSX1,INPPL1,RUNX2,SMAD9,BMPR2,PTPN6,FOXN3,DCHS1,NSD2,CHSY1,BMP6,COL27A1,SKI,PLS3,PTPRC,FAT4,INSIG1,TFAP2A,SH3PXD2B,LRRK1,BMP4,SERPINH1,SHOX2,MMP16,ZNF385A,MEF2C |
| 8.766e-03 | -4.74 | SLC7A11 (solute carrier family 7 member 11) | protein interactions | 23657 | 5 | 3 | 17029 | 1718 |
SLC3A2,TERT,TTC30B |
| 8.766e-03 | -4.74 | DOC2B (double C2 domain beta) | protein interactions | 8447 | 5 | 3 | 17029 | 1718 |
DOC2A,UNC13B,STXBP1 |
| 8.766e-03 | -4.74 | SCN8A (sodium voltage-gated channel alpha subunit 8) | protein interactions | 6334 | 5 | 3 | 17029 | 1718 |
FGF13,GNAO1,NEDD4 |
| 8.766e-03 | -4.74 | INSC (INSC, spindle orientation adaptor protein) | protein interactions | 387755 | 5 | 3 | 17029 | 1718 |
GPSM2,PARD3B,GPSM1 |
| 8.766e-03 | -4.74 | BNC1 (basonuclin 1) | protein interactions | 646 | 5 | 3 | 17029 | 1718 |
BBC3,HRK,BIK |
| 8.766e-03 | -4.74 | PRRG2 (proline rich and Gla domain 2) | protein interactions | 5639 | 5 | 3 | 17029 | 1718 |
YAP1,BAG3,NEDD4 |
| 8.766e-03 | -4.74 | Mprip (myosin phosphatase Rho interacting protein) | protein interactions | 26936 | 5 | 3 | 17029 | 1718 |
UACA,AGAP2,RAI14 |
| 8.766e-03 | -4.74 | FGF4 (fibroblast growth factor 4) | protein interactions | 2249 | 5 | 3 | 17029 | 1718 |
FGFR4,NRP1,FGFR1 |
| 8.766e-03 | -4.74 | ZNF774 (zinc finger protein 774) | protein interactions | 342132 | 5 | 3 | 17029 | 1718 |
MID2,RBM11,BEGAIN |
| 8.766e-03 | -4.74 | ANXA9 (annexin A9) | protein interactions | 8416 | 5 | 3 | 17029 | 1718 |
ARHGEF10L,NDUFA4L2,NEDD4 |
| 8.786e-03 | -4.73 | positive regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070304 | 150 | 24 | 17256 | 1658 |
PAK1,TNIK,EDA2R,FZD4,FZD8,PKN1,PLCB1,TPD52L1,TLR6,TNFRSF19,DKK1,TLR3,ERN1,MAP3K21,DUSP19,INAVA,DAB2IP,SEMA3A,TNFRSF11A,SYK,MID1,MAP3K20,RASGRP1,HMGCR |
| 8.799e-03 | -4.73 | human chr10q26.13 | chromosome location | human chr10q26.13 | 40 | 8 | 26185 | 1967 |
IKZF5,TACC2,EEF1AKMT2,CPXM2,CTBP2,PLEKHA1,LHPP,MIR4296 |
| 8.822e-03 | -4.73 | GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 203 | 31 | 17377 | 1707 |
NBL1,MSX1,ACVR1,BMPR2,MSTN,RASL11B,SYNJ2BP,ACVR2B,BMP6,MECOM,NEO1,SKI,DKK1,SMAD3,INHBC,TGFBR3,PMEPA1,FBN1,DACT1,WWTR1,CHRDL1,INHBE,BMP1,ACVR2A,BMP4,BMPR1A,SMAD6,MAGI2,PCSK6,FZD1,NKX2-1 |
| 8.892e-03 | -4.72 | MORF_PTPRB | MSigDB lists | MORF_PTPRB | 236 | 35 | 17377 | 1707 |
RUNX2,CFH,GABRB2,RGS7,NRXN1,FAM13A,PRKCA,TPD52L1,COL14A1,FAM110B,PPM1E,FRY,PDE10A,PRKG1,COL19A1,HRK,PDE4D,ST8SIA1,MYT1,NEB,B4GALT6,GCA,OPLAH,KLHL23,EXOC6B,GPR19,GPLD1,ZNF266,MAP2,ITGA2,HOXD13,TANC2,NR3C2,SMYD3,CACNA2D1 |
| 8.901e-03 | -4.72 | Metabolism of serotonin | REACTOME pathways | R-HSA-380612 | 2 | 2 | 10287 | 971 |
MAOA,ALDH2 |
| 8.901e-03 | -4.72 | Cysteine formation from homocysteine | REACTOME pathways | R-HSA-1614603 | 2 | 2 | 10287 | 971 |
CBS,CTH |
| 8.908e-03 | -4.72 | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN | MSigDB lists | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN | 195 | 30 | 17377 | 1707 |
BDNF,FARP1,PLEKHA8,PSTPIP2,STXBP6,UBASH3B,KIF5C,PRICKLE1,GALNT13,PRKAR2B,ARRDC4,DSP,HSPA12B,AHRR,ENTPD1,IFT81,ENPP1,PTPRJ,PLAGL1,HPSE,KLF12,BCHE,CSF1,MYO3B,ACVR2A,CPXM2,MED7,VWA5A,RNF157,FRMD5 |
| 8.915e-03 | -4.72 | INSR (insulin receptor) | protein interactions | 3643 | 113 | 20 | 17029 | 1718 |
ARHGAP26,PRKAA2,VAV3,INPPL1,SORBS1,GRB14,KIF5A,PTPN6,STAT5B,RACK1,PRKCA,DOK5,PTPRC,MOK,IRS2,ENPP1,IGF1R,PRKCD,DUSP19,GRB10 |
| 8.925e-03 | -4.72 | GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP | MSigDB lists | GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP | 147 | 24 | 17377 | 1707 |
SSH3,ANTXR2,LANCL3,PLEKHA5,SLK,DNAJC3,XYLT1,RNF125,SLC2A13,GUCY1A2,SNTB1,APBA1,FKBP9,ARHGAP21,FGR,FRY,RND3,PMAIP1,GPR155,NRP1,SUSD4,IL9R,ATP2B1,STOM |
| 8.926e-03 | -4.72 | PPFIA3 (PTPRF interacting protein alpha 3) | protein interactions | 8541 | 19 | 6 | 17029 | 1718 |
PTPRS,PTPRU,PTPRD,PPFIA2,PPFIBP1,PPFIBP2 |
| 8.926e-03 | -4.72 | PCCA (propionyl-CoA carboxylase subunit alpha) | protein interactions | 5095 | 19 | 6 | 17029 | 1718 |
SGK1,TTC1,PRKN,ERRFI1,LGALS3,LAMP3 |
| 8.926e-03 | -4.72 | SHANK1 (SH3 and multiple ankyrin repeat domains 1) | protein interactions | 50944 | 19 | 6 | 17029 | 1718 |
DLGAP1,RPS6KA2,ADGRL2,ADGRB2,BAIAP2,ADGRL1 |
| 8.945e-03 | -4.72 | LRFN1 (leucine rich repeat and fibronectin type III domain containing 1) | protein interactions | 57622 | 91 | 17 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,SH3BP4,TANC2,KIF1B,OSBPL6,LARP1,GAB2 |
| 8.946e-03 | -4.72 | CHOP-ATF4 complex | cellular component | GO:1990617 | 2 | 2 | 18223 | 1724 |
ATF4,DDIT3 |
| 8.946e-03 | -4.72 | CHOP-C/EBP complex | cellular component | GO:0036488 | 2 | 2 | 18223 | 1724 |
CEBPB,DDIT3 |
| 8.946e-03 | -4.72 | primary dendrite | cellular component | GO:0150001 | 2 | 2 | 18223 | 1724 |
MAP1A,MAP2 |
| 8.946e-03 | -4.72 | CHOP-ATF3 complex | cellular component | GO:1990622 | 2 | 2 | 18223 | 1724 |
ATF3,DDIT3 |
| 8.946e-03 | -4.72 | IRE1-RACK1-PP2A complex | cellular component | GO:1990630 | 2 | 2 | 18223 | 1724 |
RACK1,ERN1 |
| 8.962e-03 | -4.71 | GO_ORGANIC_ACID_METABOLIC_PROCESS | MSigDB lists | GO_ORGANIC_ACID_METABOLIC_PROCESS | 909 | 111 | 17377 | 1707 |
PLA2G4A,NMNAT3,UGT8,ACSL1,ELOVL4,AASS,UGDH,XYLT1,ASS1,STAT5B,SLC7A2,ABAT,LPIN3,BCAN,AARS,CYP26A1,QPRT,ASNS,AADAT,KMO,FAAH2,ALDOC,ALDH1L1,FABP6,MDH1B,ENO1,GATM,CTH,GLDC,CYP1B1,VNN2,GARS,SESN2,GAPDH,ATF4,UROS,PFKFB2,ALDH1L2,ACO1,PRKAR2B,GSTO1,SNCA,WARS,PYCR1,ENPP1,HPSE,TDO2,PEMT,ALDOA,TNFRSF1A,BDH2,PAM,P4HA1,HPGD,DSEL,CYP2U1,HS3ST3B1,PPARGC1A,SPOCK3,PSPH,CRYL1,HS6ST3,UST,CARS,GPT2,PRKAA2,EHHADH,ALOX5AP,ENO2,GCAT,CYP2J2,ST6GAL1,ELOVL7,OLAH,CYP4V2,CBS,SCD,CHSY1,SLC1A3,PHGDH,ADSSL1,MSMO1,GHR,HS3ST5,SLC16A9,SYK,B4GALT6,NOS3,PFKFB4,CHSY3,FADS1,PNP,SLC27A2,ELOVL3,FASN,OGDHL,MARS,AMDHD1,LRAT,GLCE,DAGLA,MAPKAPK2,DDAH1,GSTO2,XBP1,SLC7A5,HK2,HK1,PTGES,OCLN,ACSM3 |
| 8.969e-03 | -4.71 | ear | COSMIC cancer mutations | ear | 631 | 80 | 17385 | 1698 |
CELSR3,ZNF311,BEGAIN,MSR1,HECW2,CHUK,DENND3,COL14A1,TIAM2,FSTL5,SLC9A7,COL22A1,EPB41L3,RPS6KA2,UNC13B,KMO,JAKMIP2,TLN2,MET,TLR4,KCNB2,PDGFRB,DPP10,GDAP1,DCC,SPOCD1,TDRD3,ANK2,KLHL4,ROR1,MFSD6,FGFR1,TMEM132B,PTK7,ITGA2,LAMB1,PTPRS,ZBTB20,CYP2U1,SUSD4,PPARGC1A,MAGI2,STON2,LIFR,MEF2C,PCSK5,PCDH18,INPPL1,ARHGEF11,ZHX3,PTPRD,IGF2BP2,WDFY4,SLC12A6,USP30,SATB1,FRY,PIK3AP1,FRAS1,STC2,PRKG1,MARCH3,PRICKLE2,IQGAP3,CHRM3,RBMS2,SYNPO2,AGPAT4,LITAF,SDK1,PALLD,KHDRBS2,MAPKAPK2,FAT4,TERT,LRRIQ3,INHBE,DLG2,PLD1,AMPD1 |
| 8.973e-03 | -4.71 | striated muscle tissue development | biological process | GO:0014706 | 284 | 40 | 17256 | 1658 |
ACVR1,BMPR2,BVES,PKP2,DNER,MYORG,FHOD3,SKI,FOXP2,TGFBR3,EEF2,KCNAB1,EOMES,DSG2,COL19A1,MYH15,PDGFRB,MYLK3,FHL2,RYR2,ATF3,CBY1,ZFPM2,DSP,GJC1,HEG1,MSC,HLF,RIPOR2,POPDC3,HEYL,SVIL,SEMA3C,KLF5,MYOM2,BMPR1A,BMP4,ATG5,TPM1,MEF2C |
| 8.974e-03 | -4.71 | GO_MULTICELLULAR_ORGANISM_METABOLIC_PROCESS | MSigDB lists | GO_MULTICELLULAR_ORGANISM_METABOLIC_PROCESS | 86 | 16 | 17377 | 1707 |
MRC2,COL6A2,ID1,COL4A3,COL4A4,COL18A1,COL4A5,MMP15,ADAMTS3,COL25A1,GHR,ADRB1,COL19A1,PPARGC1A,SERPINH1,MMP16 |
| 8.974e-03 | -4.71 | GO_ESTABLISHMENT_OF_CELL_POLARITY | MSigDB lists | GO_ESTABLISHMENT_OF_CELL_POLARITY | 86 | 16 | 17377 | 1707 |
UST,AMOTL1,DOCK7,FGF13,ARHGEF11,MPP7,PTK7,CYTH3,RAP2A,WWC1,GPSM2,EPHB1,DOCK2,SPRY2,JAM3,MAP1B |
| 8.976e-03 | -4.71 | GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN | MSigDB lists | GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN | 187 | 29 | 17377 | 1707 |
FGFR4,NECAB1,KCNQ3,CELSR3,GJB2,ARID5B,DUSP9,SELL,SNTB1,PHGDH,NAALADL2,HERPUD1,MTUS1,TBC1D2,CDS1,GALNT3,SIPA1L2,RPS6KA2,MAP1A,CPVL,BHLHA15,GPR160,ALDOA,COL19A1,POU2F2,NRP1,ENO1,GFRA1,FES |
| 8.976e-03 | -4.71 | GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN | MSigDB lists | GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_DN | 187 | 29 | 17377 | 1707 |
AVPI1,MYLK3,ABCC4,ENO2,KDM5B,BTNL9,TNS1,PALLD,FAM110B,NOS1AP,SKI,PPP1R26,SOAT2,RNF217,PKN3,FAM168A,MYC,ACER2,ITGB3,ALDH1L1,RAP2A,GHR,TNFRSF1A,PRKG1,RAB31,PAM,GRB10,ZNF235,DUSP1 |
| 8.976e-03 | -4.71 | GSE35543_IN_VIVO_NTREG_VS_CONVERTED_EX_ITREG_DN | MSigDB lists | GSE35543_IN_VIVO_NTREG_VS_CONVERTED_EX_ITREG_DN | 187 | 29 | 17377 | 1707 |
WASF3,RGS16,PCSK1N,NECAB1,WISP3,COL4A4,LPCAT2,PTPN13,CD276,LMCD1,MORC4,ATP6V1E2,PHACTR2,TSPAN17,CA13,DDAH1,SIPA1L2,PPP1R26,TACC2,FLRT3,RAB26,HGF,CYP2U1,DLX2,NRP1,GLIS1,SLC45A3,SPOCK3,RAB30 |
| 8.976e-03 | -4.71 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_UP | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_UP | 187 | 29 | 17377 | 1707 |
EXPH5,USP2,ALDH2,KDM5B,ARHGEF11,RAPGEF4,MCOLN3,SLC25A27,NDRG2,SLC36A4,INTS6,SATB1,SKAP1,BBS9,PGAP1,QPRT,RASSF8,TECPR1,IGF1R,RALGPS2,PLAGL1,FAM168A,CNKSR3,EIF1,TSC22D1,P4HA1,PJA1,SUSD4,CRISPLD1 |
| 8.976e-03 | -4.71 | GSE22025_UNTREATED_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_UNTREATED_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | 187 | 29 | 17377 | 1707 |
EXPH5,EPHA3,PRKAA2,SCN5A,PAGE1,DNM3,MSTN,GCAT,EXOC6B,LRP4,RNF24,KHDRBS2,SLC9A7,GJC1,EPCAM,NACC2,NCAM2,PTK7,ATP7B,KCNG1,ERN1,B3GALT2,GSTM3,TPM1,ATP2B4,CTNND2,CAND2,FOXA1,GAB2 |
| 8.976e-03 | -4.71 | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | 187 | 29 | 17377 | 1707 |
SESN2,ABCC4,BMPR2,RECK,UBASH3B,AGPAT4,TNFSF13B,TUBE1,LRRC49,TMEM170B,COLEC10,PRKCA,PFN2,KIAA1958,HMGCS1,HPSE,GPR155,MATN2,MYO3B,DBP,PROS1,TMEFF2,VGLL4,CPE,SYK,PURG,SLC16A10,FES,FRMD5 |
| 8.976e-03 | -4.71 | GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE15324_ELF4_KO_VS_WT_NAIVE_CD8_TCELL_UP | 187 | 29 | 17377 | 1707 |
B9D1,PDLIM7,OPLAH,BMPR2,GCAT,PANK1,KIF5C,PRDM8,RNF24,NPDC1,IKZF2,TEX9,STEAP1,SMPDL3B,BAIAP2,TEX15,RPS6KA2,SLC22A17,GRHL1,PPFIA2,WFS1,C1orf21,ITGB3,MORN2,SPRED3,CMPK2,TNFSF4,PLTP,PURG |
| 8.976e-03 | -4.71 | GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP | MSigDB lists | GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP | 187 | 29 | 17377 | 1707 |
QSOX1,PODXL2,SH3BP2,MVK,TRIM2,TSPAN15,ESRRG,COL4A4,CYB5R2,BLVRB,LMCD1,CR2,OR51B4,FGF17,RADIL,ILDR2,C1orf174,GPC6,NELL2,SLC22A18,FLRT3,TMEM86A,CCDC169,NDUFB8,PIP5KL1,FBRSL1,SLFN5,TNFRSF11A,NUDT17 |
| 9.005e-03 | -4.71 | V$HOX13_01 | MSigDB lists | V$HOX13_01 | 44 | 10 | 17377 | 1707 |
UNC5C,CDR2L,SVIL,PPP2R2B,UNC5B,COLEC10,GPR161,FOXA1,GNAI1,NEO1 |
| 9.005e-03 | -4.71 | MODULE_533 | MSigDB lists | MODULE_533 | 44 | 10 | 17377 | 1707 |
TUBB4A,TACC2,KIF5A,LAMB1,KIF5C,SNAP25,NCAM1,SEPT5,DYNC1I1,MID1 |
| 9.005e-03 | -4.71 | PID_DELTA_NP63_PATHWAY | MSigDB lists | PID_DELTA_NP63_PATHWAY | 44 | 10 | 17377 | 1707 |
TCF7L1,DLX6,FASN,YAP1,RAB38,POU2F2,PERP,SFN,CEBPD,IGFBP3 |
| 9.005e-03 | -4.71 | GO_ENDOCHONDRAL_BONE_MORPHOGENESIS | MSigDB lists | GO_ENDOCHONDRAL_BONE_MORPHOGENESIS | 44 | 10 | 17377 | 1707 |
INPPL1,RUNX2,BMPR2,BMP4,SERPINH1,SHOX2,MMP16,BMP6,COL27A1,MEF2C |
| 9.023e-03 | -4.71 | TGFB_UP.V1_DN | MSigDB lists | TGFB_UP.V1_DN | 179 | 28 | 17377 | 1707 |
MN1,TRPM4,PPP1R3D,VAV3,UGT8,AVPI1,ID1,EHHADH,ZNF395,LGR4,ARID5B,SYBU,PLXNA2,GATA3,RAB38,SAV1,FAM13A,EYA4,GNAI1,ENTPD7,TFAP2A,BCL6,MPPED2,ATRNL1,TUFT1,SPRY2,RIMS2,PGBD5 |
| 9.023e-03 | -4.71 | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_UP | MSigDB lists | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_UP | 179 | 28 | 17377 | 1707 |
SERINC5,CARD6,TCP11L2,TUBA1A,LGALS3,PRSS12,BTNL9,KCNH5,WLS,AGPAT4,RAPGEF4,ATF3,NPC2,APBA1,ABHD4,SLC19A2,CRYBG3,GPC6,STK24,COL27A1,SCIN,GJC1,OTUD1,FRY,GNB4,GPR155,STARD4,TSC22D1 |
| 9.023e-03 | -4.71 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP | 179 | 28 | 17377 | 1707 |
MID2,COL6A2,ANKRD13D,ACSL1,ITPRIP,REL,GPR65,RAPGEF2,DNAJC3,CYTH3,RNF125,MAPKAPK2,CAMK2N1,IDI1,IKZF5,BACH2,ZFYVE28,PELI2,OSBPL5,BCL6,SGK3,COG3,PTPRE,SFN,RBMS2,CKAP4,ATP2B1,RAB30 |
| 9.023e-03 | -4.71 | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP | MSigDB lists | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP | 179 | 28 | 17377 | 1707 |
B9D1,SSH3,IGFBP6,ZCCHC24,DNAJC3,ITGA6,C3orf52,DEPTOR,ASS1,ZNF215,PRKAR2B,PRDM1,CHAC1,AARS,BMP6,NT5DC2,SMPDL3B,PPP2R3A,PPP1R26,TERT,XBP1,RAB26,FAR2,TNFRSF17,AMPD1,RAB30,CTH,GLDC |
| 9.023e-03 | -4.71 | TGFB_UP.V1_UP | MSigDB lists | TGFB_UP.V1_UP | 179 | 28 | 17377 | 1707 |
TMC7,BMPR2,CYP2J2,RUSC2,RAPGEF2,LMCD1,FERMT2,MAFB,WNT11,ATF3,OVOL2,PLEKHA1,SKAP1,TUBB4A,ID3,FAT4,PMEPA1,PAIP2B,DACT1,SMTN,SGK1,PPP2R2B,FNBP1L,SMAD6,JAM2,LRP12,PKIA,ABCG1 |
| 9.023e-03 | -4.71 | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN | 179 | 28 | 17377 | 1707 |
FADS1,INPPL1,SEC24D,MYO10,NR4A1,JDP2,LRP4,ATOX1,LITAF,NUAK2,RASL11B,ATF3,CEBPB,ID3,DOCK7,PLK2,MYC,PDE4D,SPRY4,CTTN,TPM1,ARL4D,HSPA2,SPRY2,CEBPD,TBC1D8,GAB2,DUSP1 |
| 9.039e-03 | -4.71 | GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_DN | 163 | 26 | 17377 | 1707 |
EFNB2,MICAL2,SEMA6B,OPLAH,CELSR1,IGFBP6,MPP1,BNIP3L,DUSP9,EXOG,SLCO3A1,GAS1,SMPDL3B,SNCA,KCNJ4,HEYL,MATN2,EIF1,RAB31,HGF,STEAP3,TESC,DOCK6,LZTS1,RRAGD,HRASLS |
| 9.045e-03 | -4.71 | GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_UP | 171 | 27 | 17377 | 1707 |
B9D1,NBL1,LPAR2,IGFBP6,HERC5,KCND3,ATP1B1,ARHGAP44,RERE,CTIF,PYCR1,RPS6KA2,KIAA0895,PPFIBP1,HK2,SCRN1,HGF,DLX2,ST8SIA1,WWC2,NRP1,MET,SMAD6,IL1RAP,CSRP2,ABCG1,LAMP3 |
| 9.056e-03 | -4.70 | LAM_G_DOMAIN | prosite domains | PS50025 | 35 | 9 | 12060 | 1278 |
CELSR1,FAT4,CELSR3,CNTNAP3,FAT1,PROS1,GAS6,NRXN1,SLIT2 |
| 9.094e-03 | -4.70 | Sushi | pfam domains | PF00084 | 51 | 11 | 17054 | 1666 |
SUSD3,CD55,CFH,CFHR1,SELL,CR2,C1R,SUSD4,BCAN,SEZ6L2,C4BPB |
| 9.103e-03 | -4.70 | V$CRX_Q4 | MSigDB lists | V$CRX_Q4 | 253 | 37 | 17377 | 1707 |
MOCOS,MCTP2,CTBP2,STAT5B,CREB5,FOXG1,SATB1,EYA4,NEO1,NKX6-1,ABLIM1,RALGPS2,SOAT2,ABI3BP,SAMD11,TSC22D1,MYO3B,ATRNL1,HRK,PDE4D,ZFP36L2,ZNF385A,IGSF3,MN1,RAX,FZD4,NR6A1,ESRRG,PRDM13,SATB2,BCL11A,ENTPD1,ZBTB20,TNFSF4,LIFR,BTRC,FOXA1 |
| 9.111e-03 | -4.70 | GO_REGULATION_OF_B_CELL_ACTIVATION | MSigDB lists | GO_REGULATION_OF_B_CELL_ACTIVATION | 101 | 18 | 17377 | 1707 |
VAV3,PTPN6,TNFSF13B,STAT5B,PRDM1,PKN1,CD40,IRS2,PTPRC,IKZF3,APLF,NCKAP1L,XBP1,BCL6,TNFSF4,TLR4,SYK,MEF2C |
| 9.112e-03 | -4.70 | regulation of actin filament-based movement | biological process | GO:1903115 | 45 | 10 | 17256 | 1658 |
TRPM4,RYR2,PKP2,SCN5A,PDE4D,FGF13,DSP,ANK2,DSG2,NOS1AP |
| 9.115e-03 | -4.70 | human chr10q24.31 | chromosome location | human chr10q24.31 | 25 | 6 | 26185 | 1967 |
SCD,CHUK,SFXN3,OLMALINC,PDZD7,NDUFB8 |
| 9.138e-03 | -4.70 | TSHR (thyroid stimulating hormone receptor) | protein interactions | 7253 | 43 | 10 | 17029 | 1718 |
MOCOS,TUBA1A,FN1,PTK7,GNAO1,MLF1,RABAC1,CANX,TSHR,GNAI1 |
| 9.145e-03 | -4.69 | TMEM25 (transmembrane protein 25) | protein interactions | 84866 | 84 | 16 | 17029 | 1718 |
B3GLCT,TUBA1A,LPCAT2,GALNT12,ALDH1L2,COL18A1,COL14A1,CHST10,LMLN,SEMA4F,LAMB1,PAM,MOXD1,GALNT18,CES3,PCSK6 |
| 9.145e-03 | -4.69 | SNTA1 (syntrophin alpha 1) | protein interactions | 6640 | 84 | 16 | 17029 | 1718 |
SCN5A,ABCC4,TGFA,RYR2,ADAMTS6,GUCY1A2,MLC1,PFN2,ADGRB2,KCNJ4,ADGRB3,ADRB1,ACTA2,NEB,KIF1B,MAST1 |
| 9.165e-03 | -4.69 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | 468 | 62 | 17377 | 1707 |
CREB3L2,WASF3,MYCBP2,ACVR1,TRIM2,ID1,ZHX3,RBFOX2,SLK,MYO1B,LDLR,EPS8,RGS20,KIF5C,CTBP2,CHSY1,RGS7,PRKCA,PIBF1,STK24,ZFYVE9,NEDD4,PPP2R3A,F3,MOK,KAZN,MYC,GTF2F2,LIMCH1,RRAS2,IL1RAP,PRKACB,ATP2B1,DUSP1,VEGFC,BDNF,RIN2,MEIS2,CRIM1,MYO10,CAP2,FOXN3,RAPGEF2,ARID5B,YAP1,FERMT2,WWC1,PDE8A,SATB2,CDC42BPA,FNDC3A,MAP1B,HEG1,SMAD3,SLC7A1,ID3,KPNA3,FAT1,SEMA3C,INPP5F,FNBP1L,MID1 |
| 9.206e-03 | -4.69 | regulation of mast cell activation involved in immune response | biological process | GO:0033006 | 32 | 8 | 17256 | 1658 |
FER,FGR,GATA2,STXBP1,SYK,VAMP8,FES,GAB2 |
| 9.206e-03 | -4.69 | protein localization to synapse | biological process | GO:0035418 | 32 | 8 | 17256 | 1658 |
KIF5C,DLG2,SNAP25,NRXN1,MAP1A,PCLO,BAIAP2,ARHGAP44 |
| 9.206e-03 | -4.69 | regulation of mast cell degranulation | biological process | GO:0043304 | 32 | 8 | 17256 | 1658 |
FER,FGR,GATA2,STXBP1,SYK,VAMP8,FES,GAB2 |
| 9.227e-03 | -4.69 | NAD catabolic process | biological process | GO:0019677 | 2 | 2 | 17256 | 1658 |
NUDT12,NUDT17 |
| 9.227e-03 | -4.69 | cysteine biosynthetic process via cystathionine | biological process | GO:0019343 | 2 | 2 | 17256 | 1658 |
CBS,CTH |
| 9.227e-03 | -4.69 | abducens nerve morphogenesis | biological process | GO:0021598 | 2 | 2 | 17256 | 1658 |
MAFB,HOXA1 |
| 9.227e-03 | -4.69 | cerebral cortex tangential migration using cell-axon interactions | biological process | GO:0021824 | 2 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 9.227e-03 | -4.69 | abducens nerve development | biological process | GO:0021560 | 2 | 2 | 17256 | 1658 |
MAFB,HOXA1 |
| 9.227e-03 | -4.69 | cell-cell signaling involved in metanephros development | biological process | GO:0072204 | 2 | 2 | 17256 | 1658 |
GATA3,LGR4 |
| 9.227e-03 | -4.69 | facioacoustic ganglion development | biological process | GO:1903375 | 2 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 9.227e-03 | -4.69 | negative regulation of skeletal muscle tissue growth | biological process | GO:0048632 | 2 | 2 | 17256 | 1658 |
MSTN,TLL2 |
| 9.227e-03 | -4.69 | cell-cell signaling involved in kidney development | biological process | GO:0060995 | 2 | 2 | 17256 | 1658 |
GATA3,LGR4 |
| 9.227e-03 | -4.69 | negative regulation of spontaneous neurotransmitter secretion | biological process | GO:1904049 | 2 | 2 | 17256 | 1658 |
PRKN,PPP1R9A |
| 9.227e-03 | -4.69 | hypothalamus gonadotrophin-releasing hormone neuron development | biological process | GO:0021888 | 2 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 9.227e-03 | -4.69 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance | biological process | GO:0061394 | 2 | 2 | 17256 | 1658 |
ATF3,ATF4 |
| 9.227e-03 | -4.69 | regulation of peroxidase activity | biological process | GO:2000468 | 2 | 2 | 17256 | 1658 |
LRRK2,SNCA |
| 9.227e-03 | -4.69 | canonical Wnt signaling pathway involved in metanephric kidney development | biological process | GO:0061290 | 2 | 2 | 17256 | 1658 |
GATA3,LGR4 |
| 9.227e-03 | -4.69 | histone H3-T6 phosphorylation | biological process | GO:0035408 | 2 | 2 | 17256 | 1658 |
PRKCA,PRKCB |
| 9.227e-03 | -4.69 | hematopoietic stem cell migration to bone marrow | biological process | GO:0097241 | 2 | 2 | 17256 | 1658 |
GAS6,GPLD1 |
| 9.227e-03 | -4.69 | gonadotrophin-releasing hormone neuronal migration to the hypothalamus | biological process | GO:0021828 | 2 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 9.227e-03 | -4.69 | abducens nerve formation | biological process | GO:0021599 | 2 | 2 | 17256 | 1658 |
MAFB,HOXA1 |
| 9.227e-03 | -4.69 | response to clozapine | biological process | GO:0097338 | 2 | 2 | 17256 | 1658 |
PRKAR2B,PRKACB |
| 9.227e-03 | -4.69 | regulation of SA node cell action potential | biological process | GO:0098907 | 2 | 2 | 17256 | 1658 |
RYR2,ANK2 |
| 9.227e-03 | -4.69 | retrograde axonal protein transport | biological process | GO:0099642 | 2 | 2 | 17256 | 1658 |
DLG2,MAP1A |
| 9.227e-03 | -4.69 | hypothalamic tangential migration using cell-axon interactions | biological process | GO:0021856 | 2 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 9.227e-03 | -4.69 | protein localization to M-band | biological process | GO:0036309 | 2 | 2 | 17256 | 1658 |
OBSCN,ANK2 |
| 9.227e-03 | -4.69 | hypothalamus gonadotrophin-releasing hormone neuron differentiation | biological process | GO:0021886 | 2 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 9.227e-03 | -4.69 | Wnt signaling pathway involved in kidney development | biological process | GO:0061289 | 2 | 2 | 17256 | 1658 |
GATA3,LGR4 |
| 9.227e-03 | -4.69 | cellular response to amine stimulus | biological process | GO:0071418 | 2 | 2 | 17256 | 1658 |
ASS1,UROS |
| 9.227e-03 | -4.69 | positive regulation of lymphangiogenesis | biological process | GO:1901492 | 2 | 2 | 17256 | 1658 |
VEGFC,CCBE1 |
| 9.227e-03 | -4.69 | 10-formyltetrahydrofolate catabolic process | biological process | GO:0009258 | 2 | 2 | 17256 | 1658 |
ALDH1L2,ALDH1L1 |
| 9.227e-03 | -4.69 | corticospinal neuron axon guidance | biological process | GO:0021966 | 2 | 2 | 17256 | 1658 |
SCN1B,SLIT2 |
| 9.227e-03 | -4.69 | regulation of lateral mesodermal cell fate specification | biological process | GO:0048378 | 2 | 2 | 17256 | 1658 |
BMPR1A,FGFR1 |
| 9.227e-03 | -4.69 | negative regulation of transforming growth factor-beta secretion | biological process | GO:2001202 | 2 | 2 | 17256 | 1658 |
LILRB1,FN1 |
| 9.234e-03 | -4.68 | GO_KIDNEY_EPITHELIUM_DEVELOPMENT | MSigDB lists | GO_KIDNEY_EPITHELIUM_DEVELOPMENT | 124 | 21 | 17377 | 1707 |
EFNB2,ROBO2,SMAD9,LGR4,KLHL3,DCHS1,GATA3,WNT11,FGFR1,SMAD3,EPCAM,FAT4,MYC,HEYL,BMP4,SMAD6,MAGI2,SLIT2,SIX2,POU3F3,MEF2C |
| 9.234e-03 | -4.68 | GSE9946_IMMATURE_VS_LISTERIA_INF_MATURE_DC_UP | MSigDB lists | GSE9946_IMMATURE_VS_LISTERIA_INF_MATURE_DC_UP | 124 | 21 | 17377 | 1707 |
KCNV1,CCDC148,NKX3-2,MPP1,LRRK2,BEGAIN,MORC4,OBSCN,SDK1,DDR1,HLF,FAM114A2,PPFIA2,CCDC146,CHRDL1,NBEA,PRKG2,PLD1,TMEFF2,NIPAL2,MAGI2 |
| 9.234e-03 | -4.68 | GERY_CEBP_TARGETS | MSigDB lists | GERY_CEBP_TARGETS | 124 | 21 | 17377 | 1707 |
RGS16,ACSL1,MVD,FHL2,WWC1,RASL11B,ATF3,ADSSL1,FOXG1,BAIAP2,ID3,TRIB3,BAG3,ACTA2,SERPINI1,HGF,DBP,NRP1,DDIT3,HMGCR,DUSP1 |
| 9.246e-03 | -4.68 | RhoGAP | pfam domains | PF00620 | 65 | 13 | 17054 | 1666 |
CHN1,ARHGAP26,ARHGAP21,CHN2,ARAP2,ARHGAP22,SRGAP1,OPHN1,ARHGAP28,ARHGAP32,FAM13A,ARHGAP44,SYDE2 |
| 9.263e-03 | -4.68 | negative regulation of neurotransmitter transport | biological process | GO:0051589 | 20 | 6 | 17256 | 1658 |
LILRB1,PRKN,ABAT,PPP1R9A,ASIC1,SNCA |
| 9.268e-03 | -4.68 | Band_41_domain | interpro domains | IPR019749 | 51 | 11 | 18492 | 1811 |
FRMPD3,EPB41L5,EPB41L3,PLEKHH2,FARP1,MYO10,PTPN13,PTPN21,FERMT2,TLN2,FRMD5 |
| 9.287e-03 | -4.68 | HARRIS_HYPOXIA | MSigDB lists | HARRIS_HYPOXIA | 79 | 15 | 17377 | 1707 |
GAPDH,TGFA,ALDOA,BIK,HK2,BNIP3L,P4HA1,BNIP3,VIM,HGF,HK1,ENO1,DDIT3,F3,IGFBP3 |
| 9.292e-03 | -4.68 | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN | MSigDB lists | YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN | 245 | 36 | 17377 | 1707 |
ZSWIM5,DHCR24,SLC25A27,CADM2,KIAA1217,PRKCA,FAM131B,SPEG,SAMD11,FABP6,GRIP1,NEB,PCDH10,B3GALT1,NR6A1,COL4A4,NFIA,CHRNA6,TMEM200C,WWC1,RYR2,C4orf19,ZIC1,HTR7,PLEKHH2,PTPRJ,OR2T33,IKZF3,PDLIM3,NCAM2,THBS4,CECR2,MYOM2,PAX9,SMYD3,OSBPL6 |
| 9.298e-03 | -4.68 | GO_ALCOHOL_METABOLIC_PROCESS | MSigDB lists | GO_ALCOHOL_METABOLIC_PROCESS | 338 | 47 | 17377 | 1707 |
PLA2G4A,PRKAA2,NUDT10,INPPL1,MVK,LPCAT2,LDLR,DHCR24,CYP4V2,CEBPA,ISYNA1,LPIN3,INPP1,CDS1,CYP51A1,IDI1,HMGCS1,SOAT2,MSMO1,BCHE,SREBF1,SMPDL3A,CYP1B1,HMGCR,ALDH2,EBPL,CYB5R2,MVD,VLDLR,NPC2,PLCB1,LRAT,LEPR,SMPDL3B,GPLD1,INSIG1,ENPP6,ACER2,PEMT,OSBPL5,SRD5A3,INPP4B,SQLE,TNFSF4,DHCR7,MBOAT2,ABCG1 |
| 9.321e-03 | -4.68 | transferase activity, transferring glycosyl groups | molecular function | GO:0016757 | 289 | 41 | 17224 | 1680 |
CCDC126,GXYLT2,UGT8,GALNT12,GALNT6,ST6GAL1,XYLT1,ALG1L,GALNT13,CHSY1,MGAT5B,QPRT,GALNT1,TYMP,GBGT1,PRTFDC1,FUT9,MGAT1,ST8SIA1,AGL,GALNT18,ALG10B,B4GALT6,PARP9,CHSY3,B3GLCT,B3GALT1,GCNT2,PNP,MGAT4B,COLGALT2,GALNT17,ST6GALNAC3,B4GALNT3,GALNT14,GALNT3,DPY19L2,PLOD2,B3GALT2,ALG11,B4GALT7 |
| 9.358e-03 | -4.67 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | biological process | GO:0007157 | 52 | 11 | 17256 | 1658 |
TENM1,GYPC,FAT4,PTPRD,DCHS1,SCARF2,ADGRL1,CADM2,AMIGO1,CDH2,CBLN1 |
| 9.439e-03 | -4.66 | SMID_BREAST_CANCER_ERBB2_UP | MSigDB lists | SMID_BREAST_CANCER_ERBB2_UP | 132 | 22 | 17377 | 1707 |
TRPM4,ACSL1,SLC37A1,GCAT,SEC24D,GALNT6,LDLR,BIK,EFNA3,FASN,ASS1,IL13RA1,ABCC2,SCD,ASPH,TSKU,QPRT,MMP15,KMO,TRIM3,WWC2,SNPH |
| 9.444e-03 | -4.66 | RhoGAP_dom | interpro domains | IPR000198 | 65 | 13 | 18492 | 1811 |
CHN1,ARHGAP26,ARHGAP21,CHN2,ARAP2,ARHGAP22,OPHN1,SRGAP1,ARHGAP28,ARHGAP32,FAM13A,ARHGAP44,SYDE2 |
| 9.444e-03 | -4.66 | TSP1_rpt | interpro domains | IPR000884 | 65 | 13 | 18492 | 1811 |
ADAMTS17,UNC5C,ADGRB3,WISP3,ADAMTS3,ISM1,THSD4,THSD7B,ADAMTS6,UNC5B,THSD1,HMCN1,ADGRB2 |
| 9.468e-03 | -4.66 | GO_NEGATIVE_REGULATION_OF_CHEMOTAXIS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CHEMOTAXIS | 51 | 11 | 17377 | 1707 |
NBL1,SEMA6B,SEMA4F,ROBO2,ST6GAL1,SEMA3C,NRP1,SEMA3A,SLIT2,SEMA6A,SEMA6C |
| 9.476e-03 | -4.66 | V$TST1_01 | MSigDB lists | V$TST1_01 | 237 | 35 | 17377 | 1707 |
PCDH18,IGFBP6,KLHL13,BEGAIN,PLXNA2,FOXG1,NIPSNAP3B,RTN1,ZNF362,KCTD15,FLRT3,RAP2A,TSC22D1,SCRN1,FIGN,PRKACB,FES,GPM6A,ESRRG,MGAT4B,SLITRK5,ZIC1,MAP2,KIAA0355,B3GALT2,MPP2,INPP4B,NXPH4,P4HA1,KLF5,GRB10,DLG2,PURG,MLLT3,HEY1 |
| 9.494e-03 | -4.66 | knee | COSMIC cancer mutations | knee | 125 | 21 | 17385 | 1698 |
FER,PTPRD,DCC,PTPN13,PTPN21,RYR2,TNS1,EPHB1,KHDRBS2,PTPRC,TMEM132B,PTPRJ,ADAMTS3,PPFIBP1,PTK7,PTPRS,PTPRN2,MET,PTPRE,CHRM3,CNTN1 |
| 9.509e-03 | -4.66 | glycoprotein transporter activity | molecular function | GO:0034437 | 2 | 2 | 17224 | 1680 |
VLDLR,ABCG1 |
| 9.509e-03 | -4.66 | formyltetrahydrofolate dehydrogenase activity | molecular function | GO:0016155 | 2 | 2 | 17224 | 1680 |
ALDH1L2,ALDH1L1 |
| 9.509e-03 | -4.66 | N-acetyl-L-aspartate-L-glutamate ligase activity | molecular function | GO:0072590 | 2 | 2 | 17224 | 1680 |
RIMKLB,RIMKLA |
| 9.509e-03 | -4.66 | glutathione dehydrogenase (ascorbate) activity | molecular function | GO:0045174 | 2 | 2 | 17224 | 1680 |
GSTO1,GSTO2 |
| 9.509e-03 | -4.66 | activin receptor activity, type II | molecular function | GO:0016362 | 2 | 2 | 17224 | 1680 |
ACVR2B,BMPR2 |
| 9.509e-03 | -4.66 | oleoyl-[acyl-carrier-protein] hydrolase activity | molecular function | GO:0004320 | 2 | 2 | 17224 | 1680 |
OLAH,FASN |
| 9.509e-03 | -4.66 | acyl-[acyl-carrier-protein] hydrolase activity | molecular function | GO:0016297 | 2 | 2 | 17224 | 1680 |
OLAH,FASN |
| 9.509e-03 | -4.66 | methylarsonate reductase activity | molecular function | GO:0050610 | 2 | 2 | 17224 | 1680 |
GSTO1,GSTO2 |
| 9.509e-03 | -4.66 | cGMP-dependent protein kinase activity | molecular function | GO:0004692 | 2 | 2 | 17224 | 1680 |
PRKG2,PRKG1 |
| 9.509e-03 | -4.66 | palmitoyl-[acyl-carrier-protein] hydrolase activity | molecular function | GO:0016296 | 2 | 2 | 17224 | 1680 |
OLAH,FASN |
| 9.509e-03 | -4.66 | glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity | molecular function | GO:0047275 | 2 | 2 | 17224 | 1680 |
B3GALT1,B3GALT2 |
| 9.509e-03 | -4.66 | latrotoxin receptor activity | molecular function | GO:0016524 | 2 | 2 | 17224 | 1680 |
ADGRL2,ADGRL1 |
| 9.509e-03 | -4.66 | histone kinase activity (H3-T6 specific) | molecular function | GO:0035403 | 2 | 2 | 17224 | 1680 |
PRKCA,PRKCB |
| 9.509e-03 | -4.66 | myristoyl-[acyl-carrier-protein] hydrolase activity | molecular function | GO:0016295 | 2 | 2 | 17224 | 1680 |
OLAH,FASN |
| 9.509e-03 | -4.66 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity | molecular function | GO:0016404 | 2 | 2 | 17224 | 1680 |
HPGD,ABCC4 |
| 9.509e-03 | -4.66 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential | molecular function | GO:0086062 | 2 | 2 | 17224 | 1680 |
SCN5A,SCN1B |
| 9.519e-03 | -4.65 | MODULE_180 | MSigDB lists | MODULE_180 | 109 | 19 | 17377 | 1707 |
DPYSL5,SSH3,VAV3,SYT12,BLVRB,GATA3,DSP,TPD52L1,CDS1,TRPS1,EPCAM,ICA1,PLXDC2,GPR160,RAB26,MAP7,MYO6,FOXA1,OCLN |
| 9.519e-03 | -4.65 | SMIRNOV_RESPONSE_TO_IR_6HR_DN | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_DN | 109 | 19 | 17377 | 1707 |
CD55,PDK1,ZNF395,ATP8A1,LDLR,CR2,KCTD12,SCD,LCP2,ENTPD1,PTPRC,INSIG1,MYC,HK2,P4HA1,BNIP3,PTPRCAP,VGLL4,HEY1 |
| 9.530e-03 | -4.65 | MODULE_120 | MSigDB lists | MODULE_120 | 72 | 14 | 17377 | 1707 |
GPR176,ICA1,IGF1R,TERT,PLOD2,THBS4,DHCR24,BIK,RAB31,CR2,COL18A1,SERPINI1,SP140,HMGCR |
| 9.530e-03 | -4.65 | GO_CELLULAR_RESPONSE_TO_KETONE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_KETONE | 72 | 14 | 17377 | 1707 |
PRKAA2,FBXO32,FN1,MSTN,ADCY1,ASS1,ADCY6,KLF9,GAS6,ERRFI1,TNFSF4,SMYD3,ATP2B1,GNAI1 |
| 9.530e-03 | -4.65 | I band | cellular component | GO:0031674 | 137 | 22 | 18223 | 1724 |
PAK1,SCN5A,SYNPO2,SCN8A,ANK2,JPH1,FHL2,FERMT2,RYR2,OBSCN,PALLD,NOS1AP,FHOD3,BAG3,FBXO32,PDLIM3,KCNN2,ALDOA,AHNAK2,MYOM2,NEB,ATP2B4 |
| 9.538e-03 | -4.65 | Inhibitor_Mig-6 | pfam domains | PF11555 | 2 | 2 | 17054 | 1666 |
TNK2,ERRFI1 |
| 9.538e-03 | -4.65 | ULD | pfam domains | PF16534 | 2 | 2 | 17054 | 1666 |
SATB2,SATB1 |
| 9.538e-03 | -4.65 | Hyd_WA | pfam domains | PF06462 | 2 | 2 | 17054 | 1666 |
TECPR1,TECPR2 |
| 9.538e-03 | -4.65 | Cobl | pfam domains | PF09469 | 2 | 2 | 17054 | 1666 |
COBLL1,COBL |
| 9.538e-03 | -4.65 | COR | pfam domains | PF16095 | 2 | 2 | 17054 | 1666 |
LRRK1,LRRK2 |
| 9.538e-03 | -4.65 | Syntaphilin | pfam domains | PF15290 | 2 | 2 | 17054 | 1666 |
SYBU,SNPH |
| 9.538e-03 | -4.65 | FWWh | pfam domains | PF14922 | 2 | 2 | 17054 | 1666 |
FAM227B,FAM227A |
| 9.538e-03 | -4.65 | Neogenin_C | pfam domains | PF06583 | 2 | 2 | 17054 | 1666 |
DCC,NEO1 |
| 9.538e-03 | -4.65 | BNIP3 | pfam domains | PF06553 | 2 | 2 | 17054 | 1666 |
BNIP3,BNIP3L |
| 9.538e-03 | -4.65 | CUTL | pfam domains | PF16557 | 2 | 2 | 17054 | 1666 |
SATB2,SATB1 |
| 9.538e-03 | -4.65 | Thioesterase | pfam domains | PF00975 | 2 | 2 | 17054 | 1666 |
OLAH,FASN |
| 9.538e-03 | -4.65 | Tankyrase_bdg_C | pfam domains | PF15327 | 2 | 2 | 17054 | 1666 |
KIAA1671,TNKS1BP1 |
| 9.538e-03 | -4.65 | DUF3350 | pfam domains | PF11830 | 2 | 2 | 17054 | 1666 |
TBC1D4,TBC1D1 |
| 9.538e-03 | -4.65 | Ribosomal_L26 | pfam domains | PF16906 | 2 | 2 | 17054 | 1666 |
RPL26,RPL26L1 |
| 9.538e-03 | -4.65 | RimK | pfam domains | PF08443 | 2 | 2 | 17054 | 1666 |
RIMKLB,RIMKLA |
| 9.547e-03 | -4.65 | WHRN (whirlin) | protein interactions | 25861 | 14 | 5 | 17029 | 1718 |
VIM,TBKBP1,PXN,LRP4,MCC |
| 9.547e-03 | -4.65 | COLEC10 (collectin subfamily member 10) | protein interactions | 10584 | 14 | 5 | 17029 | 1718 |
COLGALT2,CKAP4,STC2,MCU,INHBE |
| 9.547e-03 | -4.65 | ARHGAP10 (Rho GTPase activating protein 10) | protein interactions | 79658 | 14 | 5 | 17029 | 1718 |
ARHGAP26,SH3BP2,PKN1,NRXN1,PKN3 |
| 9.547e-03 | -4.65 | ARHGAP19 (Rho GTPase activating protein 19) | protein interactions | 84986 | 14 | 5 | 17029 | 1718 |
RASA3,TDRKH,CBY1,FHIT,IKZF5 |
| 9.557e-03 | -4.65 | negative regulation of hydrogen peroxide-induced cell death | biological process | GO:1903206 | 26 | 7 | 17256 | 1658 |
GPR37,PDE8A,HGF,RACK1,MET,LRRK2,PYCR1 |
| 9.557e-03 | -4.65 | negative regulation of cellular response to drug | biological process | GO:2001039 | 26 | 7 | 17256 | 1658 |
GPR37,PDE8A,HGF,RACK1,MET,LRRK2,PYCR1 |
| 9.557e-03 | -4.65 | intracellular lipid transport | biological process | GO:0032365 | 26 | 7 | 17256 | 1658 |
LRP6,PRKAA2,NPC2,PLEKHA8,LDLR,STARD4,ABCG1 |
| 9.557e-03 | -4.65 | regulation of odontogenesis | biological process | GO:0042481 | 26 | 7 | 17256 | 1658 |
ENAM,RUNX2,BMP4,MSX1,PAX9,CSF1,TFAP2A |
| 9.557e-03 | -4.65 | negative regulation of response to reactive oxygen species | biological process | GO:1901032 | 26 | 7 | 17256 | 1658 |
GPR37,PDE8A,HGF,RACK1,MET,LRRK2,PYCR1 |
| 9.559e-03 | -4.65 | KARLSSON_TGFB1_TARGETS_DN | MSigDB lists | KARLSSON_TGFB1_TARGETS_DN | 196 | 30 | 17377 | 1707 |
RIN2,GPM6A,ID1,PNRC1,DUSP8,ZNF395,PTPN13,VAMP8,ARID5B,NFIA,BNIP3L,NDRG2,NPC2,KCND3,KCNC4,SESN1,ILDR2,GAS1,SMPDL3B,MTUS1,GABARAPL1,WARS,ID3,GSN,WWTR1,STARD4,MAOA,ZBTB20,BEND4,MET |
| 9.578e-03 | -4.65 | CAHOY_ASTROGLIAL | MSigDB lists | CAHOY_ASTROGLIAL | 94 | 17 | 17377 | 1707 |
PHACTR3,LGALS3,RHOD,ATP8A1,SPATA6,VLDLR,NUAK2,MORC4,PKP2,CCNG1,P2RY1,LPIN3,ITGBL1,ACTA2,CTTN,TMEM37,IGFBP3 |
| 9.578e-03 | -4.65 | AGGTGCA,MIR-500 | MSigDB lists | AGGTGCA,MIR-500 | 94 | 17 | 17377 | 1707 |
ATL1,GPM6A,ABCC4,CELSR3,ESRRG,NHP2,B4GALNT3,FOXG1,SP8,ZNF711,HLF,KPNA3,PLXDC2,NBEA,KLF9,FAM155B,FIGN |
| 9.578e-03 | -4.65 | GO_REGULATION_OF_MEMBRANE_POTENTIAL | MSigDB lists | GO_REGULATION_OF_MEMBRANE_POTENTIAL | 330 | 46 | 17377 | 1707 |
SCN5A,BVES,GRIK2,SCN8A,PKP2,ABAT,NRXN1,CACNB4,PPP1R9A,NEDD4,NOS1AP,UNC13B,AKAP7,PMAIP1,SCN1B,CACNB2,EHD3,DSG2,PRELID1,KCNMB3,BNIP3,SCN2A,RIMS2,SCN3A,TRPM4,KCNQ3,CACNA1E,ANK2,KCNH5,LRRK2,FGF12,CHRNA6,NLGN4X,RYR2,KCND3,ATP1B1,DSP,GJC1,PYCR1,SNCA,KCNK15,KCNMB4,POPDC3,CACNA2D1,ATP1A3,MEF2C |
| 9.586e-03 | -4.65 | SATB_ULD_sf | interpro domains | IPR038224 | 2 | 2 | 18492 | 1811 |
SATB2,SATB1 |
| 9.586e-03 | -4.65 | Memapsin-like | interpro domains | IPR033874 | 2 | 2 | 18492 | 1811 |
BACE2,BACE1 |
| 9.586e-03 | -4.65 | MAGEA3/MAGEA6 | interpro domains | IPR030097 | 2 | 2 | 18492 | 1811 |
MAGEA6,MAGEA3 |
| 9.586e-03 | -4.65 | ATP-grasp_RimK-type | interpro domains | IPR013651 | 2 | 2 | 18492 | 1811 |
RIMKLB,RIMKLA |
| 9.586e-03 | -4.65 | BNIP3 | interpro domains | IPR010548 | 2 | 2 | 18492 | 1811 |
BNIP3,BNIP3L |
| 9.586e-03 | -4.65 | 10_FTHF_DH | interpro domains | IPR011407 | 2 | 2 | 18492 | 1811 |
ALDH1L2,ALDH1L1 |
| 9.586e-03 | -4.65 | SP140 | interpro domains | IPR030411 | 2 | 2 | 18492 | 1811 |
SP140,SP140L |
| 9.586e-03 | -4.65 | GST_omega | interpro domains | IPR005442 | 2 | 2 | 18492 | 1811 |
GSTO1,GSTO2 |
| 9.586e-03 | -4.65 | Neural_cell_adh | interpro domains | IPR009138 | 2 | 2 | 18492 | 1811 |
NCAM1,NCAM2 |
| 9.586e-03 | -4.65 | Chimaerin_SH2 | interpro domains | IPR035840 | 2 | 2 | 18492 | 1811 |
CHN1,CHN2 |
| 9.586e-03 | -4.65 | CHN1/CHN2 | interpro domains | IPR017356 | 2 | 2 | 18492 | 1811 |
CHN1,CHN2 |
| 9.586e-03 | -4.65 | COR | interpro domains | IPR032171 | 2 | 2 | 18492 | 1811 |
LRRK1,LRRK2 |
| 9.586e-03 | -4.65 | SKAP_fam | interpro domains | IPR037781 | 2 | 2 | 18492 | 1811 |
SKAP2,SKAP1 |
| 9.586e-03 | -4.65 | Syntaphilin/Syntabulin | interpro domains | IPR028197 | 2 | 2 | 18492 | 1811 |
SYBU,SNPH |
| 9.586e-03 | -4.65 | Tyr-prot_kinase_Fes/Fps | interpro domains | IPR016250 | 2 | 2 | 18492 | 1811 |
FER,FES |
| 9.586e-03 | -4.65 | TF_GATA-2/3 | interpro domains | IPR016374 | 2 | 2 | 18492 | 1811 |
GATA3,GATA2 |
| 9.586e-03 | -4.65 | DUF3350 | interpro domains | IPR021785 | 2 | 2 | 18492 | 1811 |
TBC1D1,TBC1D4 |
| 9.586e-03 | -4.65 | Fes/Fps/Fer_SH2 | interpro domains | IPR035849 | 2 | 2 | 18492 | 1811 |
FER,FES |
| 9.586e-03 | -4.65 | P53_induced | interpro domains | IPR015664 | 2 | 2 | 18492 | 1811 |
TMEM47,PERP |
| 9.586e-03 | -4.65 | PET_testin | interpro domains | IPR033724 | 2 | 2 | 18492 | 1811 |
TES,LMCD1 |
| 9.586e-03 | -4.65 | Liprin-beta_SAM_rpt_1 | interpro domains | IPR037617 | 2 | 2 | 18492 | 1811 |
PPFIBP1,PPFIBP2 |
| 9.586e-03 | -4.65 | Mig-6 | interpro domains | IPR021619 | 2 | 2 | 18492 | 1811 |
TNK2,ERRFI1 |
| 9.586e-03 | -4.65 | Thioesterase | interpro domains | IPR001031 | 2 | 2 | 18492 | 1811 |
OLAH,FASN |
| 9.586e-03 | -4.65 | BACE | interpro domains | IPR009119 | 2 | 2 | 18492 | 1811 |
BACE2,BACE1 |
| 9.586e-03 | -4.65 | STKc_cGK | interpro domains | IPR035014 | 2 | 2 | 18492 | 1811 |
PRKG2,PRKG1 |
| 9.586e-03 | -4.65 | FAM227 | interpro domains | IPR029417 | 2 | 2 | 18492 | 1811 |
FAM227B,FAM227A |
| 9.586e-03 | -4.65 | RhoGAP_chimaerin | interpro domains | IPR037860 | 2 | 2 | 18492 | 1811 |
CHN1,CHN2 |
| 9.586e-03 | -4.65 | CUTL | interpro domains | IPR032355 | 2 | 2 | 18492 | 1811 |
SATB2,SATB1 |
| 9.586e-03 | -4.65 | SATB_CUTL_sf | interpro domains | IPR038216 | 2 | 2 | 18492 | 1811 |
SATB2,SATB1 |
| 9.586e-03 | -4.65 | Neogenin_C | interpro domains | IPR010560 | 2 | 2 | 18492 | 1811 |
DCC,NEO1 |
| 9.586e-03 | -4.65 | cGMP_dep_kinase | interpro domains | IPR002374 | 2 | 2 | 18492 | 1811 |
PRKG2,PRKG1 |
| 9.586e-03 | -4.65 | FAM155 | interpro domains | IPR029604 | 2 | 2 | 18492 | 1811 |
FAM155B,FAM155A |
| 9.586e-03 | -4.65 | Liprin-beta_SAM_rpt_3 | interpro domains | IPR037619 | 2 | 2 | 18492 | 1811 |
PPFIBP1,PPFIBP2 |
| 9.586e-03 | -4.65 | Inhibin_betaC | interpro domains | IPR001318 | 2 | 2 | 18492 | 1811 |
INHBC,INHBE |
| 9.586e-03 | -4.65 | Liprin-beta_SAM_rpt_2 | interpro domains | IPR037618 | 2 | 2 | 18492 | 1811 |
PPFIBP1,PPFIBP2 |
| 9.586e-03 | -4.65 | Ribosomal_L26/L24P_euk/arc | interpro domains | IPR005756 | 2 | 2 | 18492 | 1811 |
RPL26,RPL26L1 |
| 9.586e-03 | -4.65 | ASM-like_Pdiesterase_prd | interpro domains | IPR017064 | 2 | 2 | 18492 | 1811 |
SMPDL3A,SMPDL3B |
| 9.586e-03 | -4.65 | RpS6_RimK/Lys_biosynth_LsyX | interpro domains | IPR004666 | 2 | 2 | 18492 | 1811 |
RIMKLB,RIMKLA |
| 9.586e-03 | -4.65 | Tankyrase-bd_C | interpro domains | IPR032764 | 2 | 2 | 18492 | 1811 |
KIAA1671,TNKS1BP1 |
| 9.586e-03 | -4.65 | ULD | interpro domains | IPR032392 | 2 | 2 | 18492 | 1811 |
SATB2,SATB1 |
| 9.586e-03 | -4.65 | Cordon-bleu_ubiquitin_domain | interpro domains | IPR019025 | 2 | 2 | 18492 | 1811 |
COBLL1,COBL |
| 9.617e-03 | -4.64 | CAGTGTT,MIR-141,MIR-200A | MSigDB lists | CAGTGTT,MIR-141,MIR-200A | 296 | 42 | 17377 | 1707 |
SLC6A9,ZCCHC24,BACE1,PLAG1,STAT5B,IGF2BP2,NRXN1,SEMA6A,SIPA1L2,PPM1E,IKZF5,LHX6,ACVR2A,KIAA0408,FAM84B,FBXL2,ERRFI1,STXBP1,MYRIP,PRKACB,C3orf67,ATL1,RNF145,ESRRG,FOXN3,STAT4,ELMOD1,TTYH2,AK4,ATP1B1,RAB38,RNF44,KHDRBS2,IRS2,HLF,KPNA3,C1orf21,NRP1,MMP16,CTNND2,FOXA1,LPP |
| 9.643e-03 | -4.64 | cNMP-bd-like | interpro domains | IPR018490 | 38 | 9 | 18492 | 1811 |
PRKG2,PRKAR2B,POPDC3,SLC9C1,BVES,KCNH5,RAPGEF2,RAPGEF4,PRKG1 |
| 9.645e-03 | -4.64 | skin-ankle-malignant_melanoma-acral_lentiginous | COSMIC cancer mutations | skin-ankle-malignant_melanoma-acral_lentiginous | 332 | 46 | 17385 | 1698 |
EXPH5,TCP11L2,STXBP5L,KIF5A,ELOVL7,ARHGAP22,GTF2IRD1,ZNF215,CADM2,COL14A1,SLCO3A1,PPP2R3A,FHOD3,NELL2,NUMBL,JAKMIP2,FIG4,VWA5A,TSHR,KCNB2,RIMS2,INTU,PHLDB2,ALDH2,GSTM2,COL4A3,FZD4,COL4A4,FERMT2,TNS1,ARHGAP32,GUCY1A2,PLCB1,PTPRC,TMCO3,NRG3,IQCH,MAP2,PKN3,L3MBTL4,NEK11,ARHGAP28,PGM2L1,OSBPL6,SMYD3,MAST1 |
| 9.647e-03 | -4.64 | GSE27786_CD8_TCELL_VS_ERYTHROBLAST_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_ERYTHROBLAST_DN | 188 | 29 | 17377 | 1707 |
CARS,CDH26,SYNPO2,TMEM132C,IGFBP6,FZD4,WISP3,SLK,YAP1,STRADB,ZDHHC14,GAS1,TSKU,IRS2,CCDC120,LMLN,NRG3,PPP1R26,PCDHB7,CECR2,ALDH1L1,SGK3,PRKG1,MAOA,ARHGAP28,TNFSF4,CTTNBP2,GATM,CTH |
| 9.647e-03 | -4.64 | GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_DN | 188 | 29 | 17377 | 1707 |
BCL11B,RGS16,TTC39B,TBC1D1,REL,SLC39A8,STAT4,RNF125,FAM102B,PRKCQ,BATF,NDFIP2,LCP2,ABHD4,IKZF2,SLCO3A1,SLC9A7,EOMES,CSF1,XBP1,BCL6,HPGD,NIPAL2,RAB27B,GFI1,RAB30,GAB2,GLDC,RRAGD |
| 9.647e-03 | -4.64 | GSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_UP | MSigDB lists | GSE28449_WT_VS_LRF_KO_GERMINAL_CENTER_BCELL_UP | 188 | 29 | 17377 | 1707 |
EFNB2,DMXL2,RGS16,DYRK3,PNP,NR4A1,ESRRG,RASA3,TMEM47,MLC1,SLC19A2,LEPR,DDIT4,GALNT3,TLR3,INSIG1,RND3,P4HA2,KCNS3,MAP7,SERPINI1,FAM149A,BMPR1A,SPRY2,RRAGD,SNX7,PCSK5,FZD1,TBC1D8 |
| 9.647e-03 | -4.64 | GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_UP | MSigDB lists | GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_UP | 188 | 29 | 17377 | 1707 |
CXCR5,ACSL1,PNP,PRSS16,RECK,ATP9A,WLS,SLC39A8,JDP2,FAM84A,ITGA6,ELOVL3,LRMP,BIK,ASS1,PSD3,PHGDH,CRYBG3,TPK1,CXCL10,PLOD2,PRKCB,ALDOC,CDH17,HPGD,VWA5A,ENO1,KIF1B,DUSP1 |
| 9.647e-03 | -4.64 | GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP | 188 | 29 | 17377 | 1707 |
USP2,ACSL1,TMTC4,COL4A5,NOTUM,SLC12A6,CA8,DDR1,LRAT,RERE,GNAI1,PCDHB14,EPB41L3,HLF,DOCK7,CHRNA5,POPDC3,RCN3,STEAP3,TSPAN12,FIG4,BMP4,LRRK1,SLC1A5,MAPK10,OSBPL6,SNAI2,CRISPLD1,ABCG1 |
| 9.647e-03 | -4.64 | GSE360_DC_VS_MAC_T_GONDII_UP | MSigDB lists | GSE360_DC_VS_MAC_T_GONDII_UP | 188 | 29 | 17377 | 1707 |
COL9A3,FN1,TUBA1A,HOMER2,SETBP1,CBS,MARS,SNAP25,GAS6,PALLD,FAM110B,PPP2R3A,HOPX,BEX4,KCNJ4,WFS1,CACNB2,MATN2,MAOA,TPM1,APBA2,GFI1,TTC39A,MAGI2,FNBP1L,COL9A2,NPHP1,IGSF3,LAMP3 |
| 9.647e-03 | -4.64 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | 188 | 29 | 17377 | 1707 |
ANO10,ACVR1,PRSS16,CLYBL,BTNL9,TMEM126A,CYP4V2,GATA3,AK4,ABCC2,ABHD4,SLC19A2,TRPS1,NAP1L5,FKBP9,CPNE2,NAV1,RNF217,HPSE,ADAMTS3,RND3,SERPINI1,PLD1,MED7,FAM84B,FES,PDGFRB,STOM,SNX7 |
| 9.647e-03 | -4.64 | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_UP | MSigDB lists | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_UP | 188 | 29 | 17377 | 1707 |
ITGB7,GAPDH,TUBA1A,SH2D2A,NR4A1,NPM3,PTPN13,ITGA6,NDRG2,PRKCQ,ISYNA1,NPC2,ATP11A,BATF,DOCK5,SLCO3A1,IL18R1,HOPX,SKI,SPNS1,SUGT1,TNFRSF1A,RGS10,SGK1,PJA1,MYO6,RCAN3,NRP1,PDGFRB |
| 9.647e-03 | -4.64 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_180MIN_DN | 188 | 29 | 17377 | 1707 |
PFKFB4,ITGB7,PLBD2,DOCK1,KCNH5,WLS,MSR1,SELL,PSD3,PDE8A,P2RY1,CD40,USP30,TMEM74,SKI,GALNT1,CPNE2,GATA2,WFS1,PEMT,QPCTL,CNNM2,TNFRSF17,VWA5A,MBOAT2,STON2,IL9R,RASGRP1,CAND2 |
| 9.647e-03 | -4.64 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | 188 | 29 | 17377 | 1707 |
TNIK,TMEM65,NR4A1,ATP8A1,FOXN3,LITAF,FASN,SELL,SLC36A4,GABRR2,BATF,NHP2,HERC6,SLC46A3,FAM162A,HECTD2,RERE,WARS,ISG20,TMEM53,FAM189A1,AKT3,GPR155,C1orf21,RGS10,TSPAN9,KIF1B,RPS23,PARP9 |
| 9.647e-03 | -4.64 | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 188 | 29 | 17377 | 1707 |
PAK1,TRPM4,SLC3A2,FARP1,RNF145,RNF144A,RHOD,TMEM126A,LITAF,GTF2IRD1,KCTD12,PLS1,NTRK3,CD40,PHGDH,FAM174B,IKZF2,IL18R1,FAM162A,IKZF3,PTPRJ,ASNS,XBP1,OSBPL5,SH3BGRL2,ZNF518B,FES,ZNF629,C3orf67 |
| 9.647e-03 | -4.64 | GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | 188 | 29 | 17377 | 1707 |
EXPH5,GPR176,BTC,PAGE1,RHOBTB1,TBC1D1,SHANK2,SELL,CHRNA6,BATF,PRKCA,LEPR,CHST10,ZNF711,NACC2,TDO2,PTK7,CSF1,PLK2,ATP7B,SLC7A5,MPPED2,GSTM3,GFI1,ETV1,CAND2,ATP2B4,GAB2,ZNF629 |
| 9.647e-03 | -4.64 | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN | MSigDB lists | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN | 188 | 29 | 17377 | 1707 |
ALDH2,CELSR1,SCAMP1,PSTPIP2,AGPAT4,LITAF,PDE8A,VIM,PRDM1,PYGO1,TAF4B,CA13,MCOLN2,TMEM154,FCHO2,CSF1,ZDHHC6,EMILIN2,RAB31,CDH17,FIG4,GEM,TBC1D9,VWA5A,SNX10,LIFR,NR3C2,DUSP1,GAB2 |
| 9.667e-03 | -4.64 | BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN | MSigDB lists | BREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_DN | 58 | 12 | 17377 | 1707 |
ARHGAP26,TECPR1,SCN8A,CCBE1,PCBP4,GPSM1,SLX1B,SNX10,ASPH,RNF122,LIFR,KREMEN1 |
| 9.670e-03 | -4.64 | GEORGANTAS_HSC_MARKERS | MSigDB lists | GEORGANTAS_HSC_MARKERS | 65 | 13 | 17377 | 1707 |
CEBPB,CD37,IDI1,HLF,RAPGEF2,INPP4B,GATA3,LIMCH1,FAM198B,MLLT3,PLS3,MECOM,HOPX |
| 9.674e-03 | -4.64 | INHIBINBC | prints domains | PR00672 | 2 | 2 | 4652 | 458 |
INHBC,INHBE |
| 9.674e-03 | -4.64 | NCAMFAMILY | prints domains | PR01838 | 2 | 2 | 4652 | 458 |
NCAM1,NCAM2 |
| 9.674e-03 | -4.64 | CGMPKINASE | prints domains | PR00104 | 2 | 2 | 4652 | 458 |
PRKG2,PRKG1 |
| 9.674e-03 | -4.64 | GSTRNSFRASEO | prints domains | PR01625 | 2 | 2 | 4652 | 458 |
GSTO1,GSTO2 |
| 9.674e-03 | -4.64 | BACEFAMILY | prints domains | PR01815 | 2 | 2 | 4652 | 458 |
BACE2,BACE1 |
| 9.689e-03 | -4.64 | GO_REGULATION_OF_CELL_PROJECTION_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_CELL_PROJECTION_ASSEMBLY | 148 | 24 | 17377 | 1707 |
SSH3,FER,GPM6A,DNM3,RHOQ,EVL,MYO10,TBC1D1,PRKCQ,NRXN1,TBC1D16,PFN2,TBC1D30,PPP1R9A,TBC1D2,TBC1D19,PRKCD,KLF5,PLD1,ATG5,FNBP1L,SLIT2,COBL,TBC1D8 |
| 9.689e-03 | -4.64 | SERVITJA_LIVER_HNF1A_TARGETS_DN | MSigDB lists | SERVITJA_LIVER_HNF1A_TARGETS_DN | 148 | 24 | 17377 | 1707 |
FGFR4,ARHGAP26,PLA2G4A,CELSR1,AASS,ELOVL3,CYP4V2,C1R,IL13RA1,ROR1,FRK,DACH2,CYP26A1,HOPX,FRAS1,ALDH1L1,BDH2,LIN7A,CADPS2,LOXL4,LIFR,IL1RAP,DOCK8,SLC16A10 |
| 9.689e-03 | -4.64 | GO_NEUROTRANSMITTER_TRANSPORT | MSigDB lists | GO_NEUROTRANSMITTER_TRANSPORT | 148 | 24 | 17377 | 1707 |
DOC2A,SV2B,SLC6A9,SYT12,SLC1A3,SNAP25,APBA1,NRXN1,SYT14,PCLO,SNCA,TRIM9,ICA1,UNC13B,PPFIA2,LIN7A,PTPRN2,SLC6A15,CADPS2,SEPT5,STXBP1,TC2N,RIMS2,SNPH |
| 9.709e-03 | -4.63 | CYP2S1 (cytochrome P450 family 2 subfamily S member 1) | protein interactions | 29785 | 37 | 9 | 17029 | 1718 |
EPB41L3,GPRIN1,GNB4,RAP2A,MPP2,PRKCA,NCAM1,HOXB9,SMPDL3B |
| 9.713e-03 | -4.63 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP | 180 | 28 | 17377 | 1707 |
GPM6A,SKAP2,CSN2,NSUN6,GABRG2,ASS1,KCTD12,SATB2,CANX,GAS1,SPATA7,ZIC1,PTPRC,ZNF93,TM9SF2,PPFIBP1,PLK2,TECPR2,DYNC2LI1,MYOM2,RPL4,RAB27B,ZFP36L2,CHRM3,B4GALT7,ABCG1,DUSP1,STOM |
| 9.713e-03 | -4.63 | GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN | MSigDB lists | GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN | 180 | 28 | 17377 | 1707 |
PAK1,ABCC4,KIF5A,GPR65,EPS8,TNFAIP8L2,EDEM3,RASL11B,CEBPA,GPR180,GRK6,P2RY1,ZDHHC14,NCS1,AHRR,ABLIM1,TIFA,FBXO32,FRY,RND3,PELI2,MATN2,PTPRS,HPGD,PGM2L1,PACSIN1,ZFP36L2,SCN3A |
| 9.713e-03 | -4.63 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_UP | 180 | 28 | 17377 | 1707 |
UST,DZANK1,LRFN5,GARS,PPP4R4,SLC6A9,TBC1D1,IPO5,SPATS2L,ATP1B1,APBA1,PHGDH,HPCAL4,EYA4,WARS,SLC7A1,ASNS,HLF,KCTD15,INSIG1,PLK2,B3GALT2,SQLE,GULP1,PCOLCE2,CKAP4,PSPH,POU3F3 |
| 9.713e-03 | -4.63 | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_3H_DN | MSigDB lists | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_3H_DN | 180 | 28 | 17377 | 1707 |
UST,PHLDB2,ACVR1C,HEBP1,KIF5A,ARID5B,UBAC2,PRRG1,GABRG2,PEX5L,GABRR2,LDHD,ARHGEF26,GABARAPL1,DCBLD2,NKX6-1,PLAGL1,ZNF354A,KCNAB1,CCNA1,QPCTL,ZNF521,SCRN1,COL19A1,HOXD13,TMOD2,ALPK1,SEMA6C |
| 9.716e-03 | -4.63 | RYTTCCTG_V$ETS2_B | MSigDB lists | RYTTCCTG_V$ETS2_B | 1013 | 122 | 17377 | 1707 |
PHACTR3,TCP11L2,RHOD,RBFOX2,GPR65,VAMP8,PLXNA2,GATA3,STAT5B,ITPR2,CANX,DENND3,IKZF2,PCDH7,SPEG,BCL6,SERINC2,POF1B,DAB2IP,BEND4,PDE4D,SCN2A,VWA5A,TMEM132E,SEMA6C,PRKACB,SCN3A,PDGFRB,GAB2,NKX2-1,MEIS2,EVL,MARK1,GCNT2,SKAP2,KLHL3,PTPN6,NFIA,SLC25A28,PLEKHA1,CD40,TSKU,GPR150,SMAD3,ENPP1,KLF12,PTK7,GRB10,SERPINI1,HGF,NRP1,TNFSF4,MID1,MEF2C,RPS20,ZHX3,RHOBTB1,SCN8A,CMTM8,DHCR24,TNFSF13B,OVOL2,NEDD4,MCU,DDIT4,ATXN7L1,CHN2,CNTN4,SLC30A4,NOVA2,GTSF1,PCBP4,RASD2,SGK1,PRICKLE2,KLF9,NIPAL2,PTPRCAP,GFI1,RIMS2,RBMS2,RNF152,FGFR4,MICAL2,BDNF,CARD6,RIN2,MSX1,MYO10,SH2D2A,STAT4,FOXN3,VLDLR,CALCRL,WWC1,RASA3,AGAP2,AIG1,PRDM1,SKAP1,NAALADL2,MAPKAPK2,PTPRC,ID3,FGR,TMEM154,PLEKHH2,PKN3,ADAMTS3,CLDN12,MAP2K6,SH3BP4,MCC,EGFL7,SLC1A5,RNF122,NKX2-8,FILIP1,ATP2B4,TLL2,SLC43A1,PHC1 |
| 9.742e-03 | -4.63 | GNAI2 (G protein subunit alpha i2) | protein interactions | 2771 | 129 | 22 | 17029 | 1718 |
CXCR5,PDLIM7,RGS16,SLC3A2,ERGIC1,PTPRU,LRRK2,ADCY1,RGS20,RASA3,NPM1,RASD1,GPSM2,MCU,GNAI1,TTC1,IGF1R,ADCK1,GNAO1,GNB4,SCRN1,TSHR |
| 9.747e-03 | -4.63 | GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP | MSigDB lists | GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP | 156 | 25 | 17377 | 1707 |
FRMPD3,DZANK1,TFCP2L1,SV2B,LRRIQ1,HOMER2,LMCD1,TNFRSF10C,APBA1,NT5DC2,GPR15,COL22A1,SIPA1L2,TERT,RBPMS2,C1orf53,KCNS3,HGF,PAX9,LRRK1,TNFRSF17,IL1RAP,NTNG1,TBC1D8,HEY1 |
| 9.747e-03 | -4.63 | GSE37301_PRO_BCELL_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_PRO_BCELL_VS_CD4_TCELL_UP | 156 | 25 | 17377 | 1707 |
MPZL3,LPAR2,PDK1,SIDT1,RNF145,FGF13,KLHL3,TMEM65,CYTH3,PRKCQ,ADAMTS6,PLEKHA1,SNTB1,PFN2,TLR6,SLC9A7,SCIN,SFXN1,TGFBR3,PLAGL1,EHD3,TNFRSF1A,MYO3B,DISP1,RPL4 |
| 9.747e-03 | -4.63 | GSE14415_ACT_VS_CTRL_NATURAL_TREG_DN | MSigDB lists | GSE14415_ACT_VS_CTRL_NATURAL_TREG_DN | 156 | 25 | 17377 | 1707 |
CARD6,CD55,EVL,SIDT1,IL15,CLYBL,PRSS12,RAB6B,NR4A1,PLEKHA1,MFSD6,TAF4B,CD7,KBTBD11,FAM162A,RNF141,ZFP62,AKT3,GPR155,RUNDC3B,ZBTB20,SMYD3,SMPDL3A,DIRC2,DUSP1 |
| 9.754e-03 | -4.63 | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_UP | MSigDB lists | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_UP | 172 | 27 | 17377 | 1707 |
GXYLT2,ERGIC1,MYO10,KLHL3,MPP1,STAT4,CYP2J2,PTPN6,EFHC2,PPFIBP2,ATP6V1E2,SELL,FAM117B,ARHGEF26,BAIAP2,LMLN,BACH2,LRRN1,BACE2,KIAA0319,ZNF474,IPCEF1,POU2F2,RCAN3,RNF157,SPOCK3,PCSK6 |
| 9.754e-03 | -4.63 | GSE2706_2H_VS_8H_R848_STIM_DC_DN | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_DN | 172 | 27 | 17377 | 1707 |
PLA2G4A,VNN2,LRRIQ1,TGFA,COBLL1,HERC5,FEZ1,FAM110B,NIPSNAP3B,PGAP1,WARS,ASNS,SLC7A11,SH3GL2,PLOD2,GBP1,FAAH2,SEMA3C,INPP5F,TNFSF15,CMPK2,TNFSF4,TBC1D4,KIAA1211,IGSF3,TBC1D8,PARP9 |
| 9.757e-03 | -4.63 | Focal adhesion | KEGG pathways | ko04510 | 198 | 31 | 7161 | 730 |
PAK1,VEGFC,COL9A3,ITGB7,VAV3,PXN,COL6A2,MYLK3,FN1,COL4A3,PAK5,DOCK1,COL4A4,ITGA6,LAMC3,COL4A5,PRKCA,RAC3,IGF1R,PRKCB,THBS4,AKT3,ITGA2,LAMB1,ITGB3,HGF,MET,TLN2,MAPK10,COL9A2,PDGFRB |
| 9.757e-03 | -4.63 | Focal adhesion | KEGG pathways | hsa04510 | 198 | 31 | 7161 | 730 |
PAK1,VEGFC,COL9A3,ITGB7,VAV3,PXN,COL6A2,MYLK3,FN1,COL4A3,PAK5,DOCK1,COL4A4,ITGA6,LAMC3,COL4A5,PRKCA,RAC3,IGF1R,PRKCB,THBS4,AKT3,ITGA2,LAMB1,ITGB3,HGF,MET,TLN2,MAPK10,COL9A2,PDGFRB |
| 9.764e-03 | -4.63 | locomotory behavior | biological process | GO:0007626 | 184 | 28 | 17256 | 1658 |
PRKN,USP2,PDE1B,CELSR1,PAK5,FZD4,LRRK2,MCOLN3,FGF12,BTBD9,SNAP25,ABAT,APBA1,SELENOP,NOVA1,ZIC1,SNCA,NEGR1,GPR37,GNAO1,RASD2,CIART,GRIN2D,INPP5F,FIG4,APBA2,ZNF385A,NKX2-1 |
| 9.767e-03 | -4.63 | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 164 | 26 | 17377 | 1707 |
RIN2,INPPL1,ANKRD13D,SCAMP1,CFH,SEC24D,COBLL1,CEBPA,CTBP2,CACNB4,PPP1R9A,RNF141,ENPP1,TLR3,PRCP,ALDOC,FAM168A,OSBPL5,BCL6,PROS1,VWA5A,FMNL2,CKAP4,DOCK8,GAB2,LPP |
| 9.767e-03 | -4.63 | GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_DN | MSigDB lists | GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_DN | 164 | 26 | 17377 | 1707 |
EPHA3,BTC,PRSS16,DUSP8,GALNT12,ST6GAL1,GDPD1,ADD2,TUBE1,AIG1,SNAP25,NDFIP2,CA13,MECOM,GPR37,CHN1,GALNT1,TIFA,ZNF354A,TDO2,SLC22A18,CLDN12,ARL4D,FAM155A,CTNND2,SMPDL3A |
| 9.797e-03 | -4.63 | CTAWWWATA_V$RSRFC4_Q2 | MSigDB lists | CTAWWWATA_V$RSRFC4_Q2 | 339 | 47 | 17377 | 1707 |
TYRO3,INPPL1,PLSCR4,RHOBTB1,GABRB2,LMCD1,NDRG2,IKZF2,MCU,ABLIM1,CHN2,REEP1,OPN3,TSC22D1,TSPAN13,LOXL4,NPTXR,RIMS2,TRPM4,PPP1R3D,RHOQ,USP2,NR4A1,MGST3,PANK1,TCEA3,FGF12,TTYH2,ATF3,PALLD,ASPH,SLC7A1,SMAD3,PMEPA1,ALDOA,TMEM117,GRIN2D,MYOM2,DLG2,DIRAS1,TNFRSF17,PPARGC1A,MBOAT2,AMPD1,CTNND2,ATP2B4,CNTN1 |
| 9.825e-03 | -4.62 | spinal_cord | COSMIC cancer mutations | spinal_cord | 149 | 24 | 17385 | 1698 |
ANO10,QSOX1,ACSL1,ACVR1,LDLR,FHDC1,NPM1,NTRK3,CEBPA,SDK1,CA13,FGFR1,TRIB3,DOCK7,TERT,DNAH6,MATN2,PRICKLE2,TNFSF4,MET,TSHR,KIAA1549,SEMA6C,CNTN1 |
| 9.825e-03 | -4.62 | GO_REGULATION_OF_ACTION_POTENTIAL | MSigDB lists | GO_REGULATION_OF_ACTION_POTENTIAL | 38 | 9 | 17377 | 1707 |
TRPM4,SCN5A,ANK2,DSG2,RYR2,PKP2,DSP,CACNA2D1,NOS1AP |
| 9.825e-03 | -4.62 | GO_MESENCHYME_MORPHOGENESIS | MSigDB lists | GO_MESENCHYME_MORPHOGENESIS | 38 | 9 | 17377 | 1707 |
SMAD3,MSX1,HEYL,DCHS1,ACTA2,WNT11,BMPR1A,SNAI2,HEY1 |
| 9.877e-03 | -4.62 | SPTB (spectrin beta, erythrocytic) | protein interactions | 6710 | 25 | 7 | 17029 | 1718 |
RASA3,NMNAT3,NCAM1,SH2D2A,RHOD,GAN,TXNDC5 |
| 9.877e-03 | -4.62 | PRKACG (protein kinase cAMP-activated catalytic subunit gamma) | protein interactions | 5568 | 25 | 7 | 17029 | 1718 |
RYR2,PRKAR2B,AKAP7,AKAP5,MLF1,PRKACB,GPR161 |
| 9.877e-03 | -4.62 | HM13 (histocompatibility minor 13) | protein interactions | 81502 | 25 | 7 | 17029 | 1718 |
TMEM67,TCTN2,ATP2B4,XBP1,ATP2B1,UBAC2,STOM |
| 9.880e-03 | -4.62 | response to retinoic acid | biological process | GO:0032526 | 104 | 18 | 17256 | 1658 |
EPHA3,GDAP1,TRIM16,FZD4,YAP1,WNT11,NTRK3,LRAT,BMP6,CYP26A1,DKK1,PTK7,ACER2,SREBF1,PTGES,TESC,PDGFRB,DUSP1 |
| 9.894e-03 | -4.62 | GO_REGULATION_OF_MAPK_CASCADE | MSigDB lists | GO_REGULATION_OF_MAPK_CASCADE | 639 | 81 | 17377 | 1707 |
NEK10,AVPI1,ID1,DUSP8,GRIK2,NDRG2,NTRK3,PRKCA,TLR3,CNKSR3,DACT1,RAP2A,DAB2IP,TLR4,RASGRP1,PDGFRB,IGFBP3,GCNT2,FZD4,PTPN6,TGFA,LRRK2,ATF3,SYNJ2BP,CD40,FGFR1,MAGI3,INHBC,PTPRJ,SH3RF1,GBP1,ERN1,BMP1,DUSP19,HGF,DIRAS1,SPRY4,NRP1,MAPK10,MID1,TNIK,EDA2R,FN1,FZD8,SORBS3,P2RY1,GAS6,EPHB1,PKN1,TPD52L1,TNFRSF19,BMP6,MECOM,IGF1R,MYC,GHR,C1QL4,PRKCD,IQGAP3,ERRFI1,TNFRSF11A,SPRY2,SYK,DUSP1,HMGCR,FGFR4,PAK1,MSTN,RAPGEF2,DUSP9,WWC1,TLR6,PLCB1,GPR37,MAPKAPK2,TRIB3,MAP2K6,PELI2,INHBE,BMP4,CDH2 |
| 9.954e-03 | -4.61 | syntaxin-1 binding | molecular function | GO:0017075 | 20 | 6 | 17224 | 1680 |
SNAP25,UNC13B,STXBP1,LRRK2,SYBU,SNPH |
| 1.002e-02 | -4.60 | KEGG_GAP_JUNCTION | MSigDB lists | KEGG_GAP_JUNCTION | 87 | 16 | 17377 | 1707 |
TUBB4A,TUBA1A,PRKCB,ADCY1,PRKG1,ADRB1,ADCY6,PRKG2,TJP1,ITPR2,GUCY1A2,PRKCA,PLCB1,PRKACB,PDGFRB,GNAI1 |
| 1.002e-02 | -4.60 | UEDA_CENTRAL_CLOCK | MSigDB lists | UEDA_CENTRAL_CLOCK | 87 | 16 | 17377 | 1707 |
RGS16,PNRC1,RASL11B,RASD1,PLEKHA1,STK24,HERPUD1,PLK2,XBP1,SGK1,SQLE,P4HA1,BMPR1A,DBP,SMPDL3A,DUSP1 |
| 1.003e-02 | -4.60 | MPP5 (membrane palmitoylated protein 5) | protein interactions | 64398 | 31 | 8 | 17029 | 1718 |
LATS2,AMOTL1,LIN7A,WWC1,YAP1,MPDZ,HOMER3,PATJ |
| 1.004e-02 | -4.60 | mesenchyme development | biological process | GO:0060485 | 201 | 30 | 17256 | 1658 |
EPB41L5,MSX1,ACVR1,BMPR2,DCHS1,YAP1,WNT11,OVOL2,ZFPM2,FGFR1,SMAD3,TGFBR3,SEMA4F,EOMES,PTK7,HEYL,WWTR1,ACTA2,LRP6,SEMA3C,HGF,BMP4,BMPR1A,NRP1,SEMA3A,SNAI2,PDGFRB,SIX2,HEY1,MEF2C |
| 1.006e-02 | -4.60 | TYR_PHOSPHATASE_2 | prosite domains | PS50056 | 81 | 16 | 12060 | 1278 |
PTPRC,SSH3,PTPRJ,DUSP8,PTPRU,CDC14B,PTPRD,PTPN6,PTPN13,PTPN21,DUSP19,PTPRN2,DUSP9,PTPRS,PTPRE,DUSP1 |
| 1.007e-02 | -4.60 | central nervous system neuron development | biological process | GO:0021954 | 74 | 14 | 17256 | 1658 |
ROBO2,SCN1B,GATA2,MAP2,DCC,RAPGEF2,LHX6,NRP1,EPHB1,SEMA3A,FOXG1,SLIT2,RAC3,TSKU |
| 1.007e-02 | -4.60 | positive regulation of B cell activation | biological process | GO:0050871 | 74 | 14 | 17256 | 1658 |
IRS2,PTPRC,VAV3,NCKAP1L,XBP1,BCL6,TNFSF13B,NSD2,STAT5B,PRDM1,TNFSF4,CD40,SYK,MEF2C |
| 1.007e-02 | -4.60 | WHEP_TRS_1 | prosite domains | PS00762 | 5 | 3 | 12060 | 1278 |
MARS,GARS,WARS |
| 1.007e-02 | -4.60 | AA_TRANSFER_CLASS_3 | prosite domains | PS00600 | 5 | 3 | 12060 | 1278 |
PHYKPL,ABAT,ETNPPL |
| 1.007e-02 | -4.60 | WHEP_TRS_2 | prosite domains | PS51185 | 5 | 3 | 12060 | 1278 |
MARS,GARS,WARS |
| 1.007e-02 | -4.60 | CARRIER | prosite domains | PS50075 | 5 | 3 | 12060 | 1278 |
ALDH1L2,ALDH1L1,FASN |
| 1.008e-02 | -4.60 | GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_CALCIUM_ION_TRANSPORT | 102 | 18 | 17377 | 1707 |
GSTM2,LGALS3,AKAP5,ANK2,RYR2,GSTO1,ATP1B1,ASPH,SNCA,CXCL10,WFS1,CACNB2,TRPC1,BMP4,TRPC3,HSPA2,PDGFRB,CACNA2D1 |
| 1.008e-02 | -4.60 | uveal_tract | COSMIC cancer mutations | uveal_tract | 598 | 76 | 17385 | 1698 |
CGN,EML5,AMOTL1,PAGE1,PDE1B,ZNF311,MYO1B,FHDC1,HECW2,PKP2,NPM1,CEBPA,NTRK3,GRK6,DOCK3,SNX9,RBM11,PCLO,DACH2,HMCN1,EPCAM,EPB41L3,MET,VWA5A,CPE,TSHR,NEB,TNK2,TMEM67,CD55,EVL,SESN2,CAP2,SHANK2,PREX1,TCEAL3,PLEKHA1,PYGO1,SESN1,TTC28,CA13,FGFR1,DCBLD2,PLK2,PTK7,GBP1,ITGA2,BMP1,BBC3,GRB10,CTNND2,CD276,SFXN3,MLC1,TTC30B,GRPEL2,ABCA5,SREBF1,ACTA2,IQGAP3,SNX7,CHSY3,CACNA1E,OBSCN,PRICKLE1,SHISA2,EXOG,PTPRC,FAT4,TERT,PRCP,THSD7B,TUFT1,MYOM2,ACSM3,TLL2 |
| 1.009e-02 | -4.60 | upper_arm | COSMIC cancer mutations | upper_arm | 589 | 75 | 17385 | 1698 |
EXPH5,DMXL2,MYCBP2,CACNG3,ATP8A1,PTPN21,ACTL8,ENAH,ITPR2,FSTL5,NELL2,PPM1E,CHRNA5,CNKSR3,PPFIBP1,MET,PTPRE,ZNF365,DNAH5,NTNG1,ALG10B,FER,PHLDB2,ATL1,MARK1,DCC,KCNH5,ALDH1L2,ADCY1,CR2,TNS1,FGFR1,ZNF569,ARMC4,IQCH,PTPRJ,PLK2,PTK7,PTPRS,PPARGC1A,STON2,SV2B,STXBP5L,ROBO2,PTPRD,HERC5,EPHB1,MECOM,FOXP2,ZNF354A,ABCA5,FUT9,PDE10A,KIAA0319,SLC16A9,LIMCH1,FIGN,AGL,PAK1,TMC7,CRIM1,COL4A4,PTPN13,PARD3B,ST6GALNAC3,PLCB1,PTPRC,TEX15,ADAMTS3,PLXDC2,LAPTM4B,PTPRN2,KIF21A,ATP2B4,ABCG1 |
| 1.010e-02 | -4.60 | ACACTAC,MIR-142-3P | MSigDB lists | ACACTAC,MIR-142-3P | 125 | 21 | 17377 | 1707 |
ARL15,ARID5B,EDEM3,FNDC3A,SP8,RERE,TRPS1,BACH2,SLC7A11,ADAMTS3,AFF2,ACVR2A,SGK1,MARCKS,SLCO4C1,TMEM132E,GFI1,FNBP1L,FMNL2,DIRC2,BOD1 |
| 1.010e-02 | -4.60 | GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP | MSigDB lists | GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP | 125 | 21 | 17377 | 1707 |
BDNF,CARD6,KDM5B,CRIM1,STAT4,ELMOD1,FAM102B,AMIGO1,DSP,KBTBD11,TLR6,BBS9,COL14A1,INPP1,SPINK5,SPATA9,FAM114A2,BDH2,PJA1,RRAS2,PRKACB |
| 1.010e-02 | -4.60 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | 125 | 21 | 17377 | 1707 |
RGS16,DYRK3,PNP,ARID5B,DHCR24,CALCRL,PDE8A,DSP,ISG20,SLC39A14,PDLIM3,GPRC5B,REEP1,RAB31,MAOA,UNC5B,RAPGEF5,CSRP2,MEF2C,PCSK6,LAMP3 |
| 1.012e-02 | -4.59 | regulation of B cell activation | biological process | GO:0050864 | 112 | 19 | 17256 | 1658 |
VAV3,PTPN6,TNFSF13B,NSD2,STAT5B,PRDM1,PKN1,CD40,PTPRC,IRS2,IKZF3,APLF,NCKAP1L,XBP1,BCL6,TNFSF4,SYK,ZFP36L2,MEF2C |
| 1.012e-02 | -4.59 | striated muscle contraction | biological process | GO:0006941 | 112 | 19 | 17256 | 1658 |
SCN5A,ARHGEF11,ANK2,FGF12,RYR2,PKP2,CHUK,KCND3,ATP1B1,GJC1,EEF2,KCNN2,SCN1B,MAP2K6,CACNB2,ALDOA,MYOM2,TPM1,CACNA2D1 |
| 1.012e-02 | -4.59 | signal transduction by protein phosphorylation | biological process | GO:0023014 | 409 | 54 | 17256 | 1658 |
TYRO3,TNIK,BTC,ACVR1,FGF13,RASAL2,BMPR2,PAK5,SLK,MAPK4,CHUK,PKN1,TNFRSF19,DOK5,STK24,MYC,ACVR2A,DAB2IP,IQGAP3,MET,NCAM1,SYK,GFRA1,ZFP36L2,RASGRP1,PDGFRB,PAK1,FGFR4,IL17RD,ACVR1C,RAPGEF2,KCNH5,LRRK2,DUSP9,STRADB,RASA3,FGF17,ACVR2B,FGFR1,IRS2,MAPKAPK2,RASGRF2,MAP2K6,ERN1,MAP3K21,MAPK13,HGF,GRIN2D,OXTR,BMPR1A,MAPK10,MAP3K20,BTRC,MEF2C |
| 1.015e-02 | -4.59 | Semaphorin | interpro domains | IPR027231 | 20 | 6 | 18492 | 1811 |
SEMA6B,SEMA3C,SEMA4F,SEMA3A,SEMA6A,SEMA6C |
| 1.015e-02 | -4.59 | Small_GTPase_Rho | interpro domains | IPR003578 | 20 | 6 | 18492 | 1811 |
RND2,RHOQ,RND3,RHOBTB1,RHOD,RAC3 |
| 1.015e-02 | -4.59 | GO_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_TRANSMEMBRANE_TRANSPORT | 1033 | 124 | 17377 | 1707 |
CACNG3,FLVCR2,GRIK2,ATP8A1,MCOLN3,ADD2,SLC7A2,ITPR2,SLC2A13,CACNB4,SLC19A2,NCS1,SLC9A7,SLC22A17,KCNN2,KCNAB1,CHRNA5,SLC22A18,SLC16A2,SLC10A7,KCNS3,TRPC1,SLC2A12,TMEM37,SCN2A,ATP6AP1L,SCN3A,KCNB2,GPM6A,SLC3A2,KCNIP3,ABCC4,LRRC8B,SFXN4,KCNH5,SLC39A8,GJB2,ATOX1,CHRNA6,ABCC2,KCND3,ATP1B1,SGK2,ASPH,ATP10D,GJC1,SPNS1,SLC39A14,SFXN1,SLC7A1,KCNMB4,ATP7B,KCNG1,BBC3,SLC9B1,DENND5B,KCNV1,PRKAA2,ANO10,SCN5A,SV2B,TMEM63C,SLC6A9,GABRB2,SCN8A,ATP6V1E2,GABRG2,SLC36A4,GABRR2,GAS6,SLC12A6,SLC1A3,SFXN3,KCNC4,MCU,MCOLN2,KCNJ4,SLC7A11,SLC30A4,SCN1B,ABCA5,CACNB2,GPR155,KCNMB3,SGK3,SGK1,SLC16A9,SLC6A15,NIPAL2,SLC45A3,ATP2B1,TRPM4,SLC40A1,SLC37A1,KCNQ3,SLC36A1,CACNA1E,GRID1,TTYH2,RYR2,RASA3,PEX5L,SLC46A3,STEAP1,PTPRC,TMCO3,GRIK4,KCNK15,MFSD9,MFSD2A,SLC2A6,SLC7A5,CDH17,GRIN2D,SLC22A15,SLC1A5,TRPC3,DDIT3,ATP2B4,CACNA2D1,SLC16A10,ATP1A3,ABCG1,SLC43A1 |
| 1.016e-02 | -4.59 | sphingolipid biosynthetic process | biological process | GO:0030148 | 89 | 16 | 17256 | 1658 |
PLPP1,UGT8,B3GALT1,ELOVL4,ACER2,PEMT,ELOVL7,ELOVL3,PLPP2,B3GALT2,HACD1,ST6GALNAC3,ST8SIA1,CERS4,CERS1,B4GALT6 |
| 1.016e-02 | -4.59 | Integrin cell surface interactions | REACTOME pathways | R-HSA-216083 | 68 | 13 | 10287 | 971 |
COL9A3,ITGB7,COL4A3,FN1,FBN1,COL4A4,ITGA6,ITGB3,ITGA2,COL18A1,JAM2,COL9A2,JAM3 |
| 1.017e-02 | -4.59 | Igbp1 (immunoglobulin (CD79A) binding protein 1) | protein interactions | 18518 | 2 | 2 | 17029 | 1718 |
MID2,MID1 |
| 1.017e-02 | -4.59 | Nedd4l (neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase) | protein interactions | 291553 | 2 | 2 | 17029 | 1718 |
TNK2,APBB1 |
| 1.017e-02 | -4.59 | Usp2 (ubiquitin specific peptidase 2) | protein interactions | 53376 | 2 | 2 | 17029 | 1718 |
USP2,NEDD4 |
| 1.017e-02 | -4.59 | Traf5 (TNF receptor-associated factor 5) | protein interactions | 22033 | 2 | 2 | 17029 | 1718 |
TNFRSF19,TNFRSF11A |
| 1.017e-02 | -4.59 | TULP1 (tubby like protein 1) | protein interactions | 7287 | 2 | 2 | 17029 | 1718 |
ARHGAP26,NRXN1 |
| 1.017e-02 | -4.59 | Tanc2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2) | protein interactions | 303599 | 2 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 1.017e-02 | -4.59 | IGKV3-20 (immunoglobulin kappa variable 3-20) | protein interactions | 28912 | 2 | 2 | 17029 | 1718 |
FN1,FOXA1 |
| 1.017e-02 | -4.59 | Rpl4 (ribosomal protein L4) | protein interactions | 64302 | 2 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 1.017e-02 | -4.59 | SEY1 (dynamin-like GTPase SEY1) | protein interactions | 854336 | 2 | 2 | 17029 | 1718 |
RTN1,ATL1 |
| 1.017e-02 | -4.59 | ZNF626 (zinc finger protein 626) | protein interactions | 199777 | 2 | 2 | 17029 | 1718 |
ID3,FHL2 |
| 1.017e-02 | -4.59 | Bcr (BCR, RhoGEF and GTPase activating protein) | protein interactions | 309696 | 2 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 1.017e-02 | -4.59 | Traf3 (TNF receptor-associated factor 3) | protein interactions | 22031 | 2 | 2 | 17029 | 1718 |
CD40,TNFRSF19 |
| 1.017e-02 | -4.59 | MDP1 (magnesium dependent phosphatase 1) | protein interactions | 145553 | 2 | 2 | 17029 | 1718 |
BAG3,DSTN |
| 1.017e-02 | -4.59 | Tanc1 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1) | protein interactions | 311055 | 2 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 1.017e-02 | -4.59 | Lyn (LYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 81515 | 2 | 2 | 17029 | 1718 |
ENO1,SNCA |
| 1.017e-02 | -4.59 | Rpl23 (ribosomal protein L23) | protein interactions | 29282 | 2 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 1.017e-02 | -4.59 | Trim3 (tripartite motif-containing 3) | protein interactions | 55992 | 2 | 2 | 17029 | 1718 |
ZFYVE28,SNCA |
| 1.017e-02 | -4.59 | Actg1 (actin, gamma, cytoplasmic 1) | protein interactions | 11465 | 2 | 2 | 17029 | 1718 |
SNCA,HACE1 |
| 1.017e-02 | -4.59 | LIM2 (lens intrinsic membrane protein 2) | protein interactions | 3982 | 2 | 2 | 17029 | 1718 |
ACTA2,LGALS3 |
| 1.017e-02 | -4.59 | Clta (clathrin, light chain A) | protein interactions | 83800 | 2 | 2 | 17029 | 1718 |
TNK2,STXBP5L |
| 1.017e-02 | -4.59 | JRK (Jrk helix-turn-helix protein) | protein interactions | 8629 | 2 | 2 | 17029 | 1718 |
BAG3,VWA5A |
| 1.017e-02 | -4.59 | Slc25a22 (solute carrier family 25 (mitochondrial carrier, glutamate), member 22) | protein interactions | 68267 | 2 | 2 | 17029 | 1718 |
ABCG1,SNCA |
| 1.017e-02 | -4.59 | Atf2 (activating transcription factor 2) | protein interactions | 81647 | 2 | 2 | 17029 | 1718 |
CEBPB,CEBPA |
| 1.017e-02 | -4.59 | Usp9x (ubiquitin specific peptidase 9, X-linked) | protein interactions | 363445 | 2 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 1.017e-02 | -4.59 | Cad (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) | protein interactions | 24240 | 2 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 1.017e-02 | -4.59 | EPX (eosinophil peroxidase) | protein interactions | 8288 | 2 | 2 | 17029 | 1718 |
TMEM237,GAN |
| 1.018e-02 | -4.59 | GO_EXTRACELLULAR_MATRIX | MSigDB lists | GO_EXTRACELLULAR_MATRIX | 409 | 55 | 17377 | 1707 |
COL9A3,LGALS3,FN1,ITGA6,LMCD1,LAMC3,COL18A1,COL4A5,CHADL,ADAMTS6,SLC1A3,BCAN,COL14A1,HMCN1,COL27A1,F3,EFEMP1,COL22A1,TGFBR3,ABI3BP,FLRT3,FRAS1,CPXM2,COL19A1,COL9A2,SLIT2,PCSK6,ENAM,COL6A2,COL4A3,WISP3,THSD4,COL4A4,CRIP2,WNT11,GSTO1,RARRES2,GPC6,GPLD1,SNCA,ADAMTS17,MMP15,ADAMTS3,FBN1,CCBE1,THBS4,MATN2,LAMB1,EMILIN2,BMP1,EGFL7,BMP4,SPOCK3,MMP16,B4GALT7 |
| 1.018e-02 | -4.59 | regulation of response to external stimulus | biological process | GO:0032101 | 765 | 93 | 17256 | 1658 |
NBL1,ZSWIM5,MVK,CFH,IL15,C4A,LDLR,VAMP8,TNFAIP8L2,PLXNA2,LILRB1,GATA3,STAT5B,BCL6B,NTRK3,SLC7A2,ABAT,NRXN1,PRKCA,CTNNA2,STK24,F3,TLR3,UNC13B,CFHR1,BCL6,PROS1,MET,TLR4,SLIT2,SNAI2,PDGFRB,PHLDB2,CD55,NOP53,RNF125,CR2,PRKCQ,RARRES2,F12,JAM3,C4BPB,FGFR1,SNCA,SMAD3,CXCL10,GPRC5B,HPSE,NCKAP1L,ITGA2,TNFRSF1A,PTPRS,HGF,SEMA3C,MAPK13,INPP5F,SUSD4,NRP1,TNFSF4,EFNB2,TYRO3,ROBO2,C1QTNF3,BMPR2,UBASH3B,NLRP14,HERC5,GAS6,CUEDC2,SPINK5,BMP6,MTUS1,IL17D,SEMA4F,PIK3AP1,PRKCD,PRKG1,TNFRSF11A,SYK,PARP9,HMGCR,NOS3,VEGFC,MPP1,CALCRL,C1R,PRDM1,TLR6,SMPDL3B,RIPOR2,THBS4,CSF1,SEMA3A |
| 1.018e-02 | -4.59 | enteropathy_type_T_cell_lymphoma | COSMIC cancer mutations | enteropathy_type_T_cell_lymphoma | 45 | 10 | 17385 | 1698 |
DMXL2,LATS2,PTPRD,CSF1,MPP2,PREX1,PSD3,DNAH5,PRR16,DOCK9 |
| 1.018e-02 | -4.59 | haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-small_intestine-lymphoid_neoplasm-enteropathy_type_T_cell_lymphoma | 45 | 10 | 17385 | 1698 |
DMXL2,LATS2,PTPRD,CSF1,PREX1,MPP2,PSD3,DNAH5,PRR16,DOCK9 |
| 1.019e-02 | -4.59 | TSPN | smart domains | SM00210 | 23 | 7 | 9493 | 1056 |
COL18A1,COL19A1,COL22A1,NELL2,COL14A1,THBS4,COL27A1 |
| 1.020e-02 | -4.59 | activation of protein kinase activity | biological process | GO:0032147 | 321 | 44 | 17256 | 1658 |
TNIK,AVPI1,FGF13,PAK5,SLK,NTRK3,GAS6,PKN1,PIBF1,STK24,TLR3,PRKCD,GHR,ITGB3,ADCY6,INAVA,DAB2IP,IQGAP3,TLR4,SYK,PRKACB,PAK1,TGFA,LRRK2,ADCY1,STRADB,DUSP9,WNT11,PRKAR2B,ACVR2B,TLR6,MAPKAPK2,NRG3,GPRC5B,NCKAP1L,MAP2K6,ERN1,MAP3K21,DUSP19,TNFSF15,HGF,BMP4,MAPK10,MAP3K20 |
| 1.020e-02 | -4.59 | GO_CORE_PROMOTER_PROXIMAL_REGION_DNA_BINDING | MSigDB lists | GO_CORE_PROMOTER_PROXIMAL_REGION_DNA_BINDING | 357 | 49 | 17377 | 1707 |
CREB3L2,BCL11B,ZNF516,RUNX2,ZNF395,JDP2,PLAG1,OTX1,GATA3,CEBPA,ZNF219,NKX6-1,FOXP2,GRHL1,MYC,TFAP2A,SREBF1,POU2F2,ZNF460,ETV1,SMAD6,CEBPD,GLI1,RAX,ATF4,KCNIP3,MEIS2,NR6A1,NKX3-2,NFIA,MEF2B,MAFB,ATF3,PRDM1,ATOH1,BATF,ZNF714,ZIC1,BATF3,BCL11A,CEBPB,SMAD3,NACC2,KLF5,HOXD13,NKX2-8,DDIT3,SIX2,MEF2C |
| 1.021e-02 | -4.58 | transferase activity | molecular function | GO:0016740 | 2446 | 271 | 17224 | 1680 |
GXYLT2,MYCBP2,ACVR1,ALG1L,STAT5B,PRKCA,TENT5C,STK24,HECTD2,MOK,TYMP,FBXO32,TGFBR3,GSTM3,KLHL29,GDAP1,KLHL3,ACVR1C,KLHL23,KLHL4,ALDH1L2,LRRK2,ACVR2B,FGF17,ZDHHC14,SH3RF1,PLK2,B3GALT2,MAPK13,DSEL,NRP1,LATS2,ALOX5AP,ST6GAL1,SLK,OLAH,HERC6,MECOM,GBGT1,PIK3AP1,ADCK1,PRKG1,ALPK1,ST8SIA1,MAST4,AGL,RNF152,PNP,MGST3,FASN,COLGALT2,NSD2,ST6GALNAC3,CDC42BPA,GSTO2,PKN3,PELI2,QPCTL,MPP2,FBXO27,SMYD3,ACSM3,EPHA3,BTC,ELOVL4,SUGCT,RNF144A,GALNT6,GALNT12,MAPK4,CHUK,GRK6,DDR1,CDS1,SPEG,TENT5A,EEF1AKMT2,ALDH1L1,PJA1,GATM,TRDMT1,GAPDH,MYLK3,B3GALT1,PDK1,RNF145,PFKFB2,KCNH5,PANK1,PRKCQ,FGFR1,MAGI3,IRS2,PRKCB,PEMT,MAP3K21,ALG11,HS3ST3B1,BMPR1A,ATG5,KLHL31,MAPK10,MID1,HACE1,GCAT,HERC5,PKN1,EPHB1,TSPAN17,NEDD4,HMGCS1,FTCDNL1,SOAT2,MGAT1,SGK3,PRKG2,PHYKPL,CERS4,FES,B4GALT6,PARP9,PFKFB4,GSTM2,HYKK,CLYBL,AGPAT4,MPP1,ELOVL3,ZDHHC15,AK4,GALNT3,TRIB3,NSD1,FGR,TERT,PLOD2,AKT3,NEK11,PGM2L1,PIP5KL1,LRRK1,HK1,CERS1,CMPK2,BTRC,B4GALT7,CCDC126,NMNAT3,TRIM2,MVK,UGT8,MGAT5B,ABAT,CHST10,QPRT,RPS6KA2,AADAT,EPHB6,GALNT18,PDGFRB,PRKACB,TNK2,MARK1,GCNT2,ROR1,SGK2,RNF44,GRK3,DYRK1B,TRIM9,AK1,ERN1,PIK3C2B,CACUL1,HS6ST3,UST,GPT2,LONRF1,PRKAA2,TYRO3,MOCOS,FBXO4,ELOVL7,GALNT13,CHSY1,RNF141,EFEMP1,GALNT1,RNF180,PRTFDC1,IGF1R,GAN,HS3ST5,MED7,FBXL2,PAK1,FGFR4,CHSY3,MID2,B3GLCT,RNF170,GSTM4,MGAT4B,EFNA3,STRADB,OBSCN,GALNT17,PRDM1,B4GALNT3,MAPKAPK2,HK2,RNF122,PANK3,PRKN,NEK10,LPCAT2,XYLT1,HECW2,RNF24,NTRK3,KBTBD11,SETDB2,RPS6KL1,ZDHHC6,MYO3B,ZDHHC23,ACVR2A,MET,HRASLS,ALG10B,CTH,FER,PRDM13,RNF125,GSTO1,FRK,ETNPPL,TPK1,RANBP2,RNF217,BACH2,PTK7,HGF,RNF130,MBOAT2,MAST1,TNIK,DYRK3,BMPR2,KLHL13,PAK5,NSUN6,PRDM8,FUT9,PRKCD,TRIM3,SGK1,MARCH3,SYK,CRIM1,NUAK2,PEAK1,GALNT14,LRAT,MGMT,DPY19L2,MAP2K6,DLG2,RNF157,MAP3K20,PTGES |
| 1.021e-02 | -4.58 | GO_PHOSPHORYLATION | MSigDB lists | GO_PHOSPHORYLATION | 1182 | 140 | 17377 | 1707 |
MVK,ACVR1,FGF13,STAT5B,PRKCA,STK24,MOK,TGFBR3,RPS6KA2,NDUFB8,EPHB6,TLR4,ENO1,RASGRP1,PRKACB,PDGFRB,TNK2,MARK1,SMAD9,ACVR1C,LRRK2,ACVR2B,FGF17,ROR1,SGK2,DYRK1B,AK1,RASGRF2,PLK2,ALDOA,ERN1,MAPK13,PIK3C2B,OXTR,MEF2C,TYRO3,PRKAA2,LATS2,SLK,TNFRSF19,DOK5,EFEMP1,IGF1R,ADCK1,MYC,PRKG1,ALPK1,NCAM1,MAST4,GFRA1,FGFR4,PAK1,IL17RD,DUSP9,OBSCN,STRADB,CDC42BPA,MAPKAPK2,PKN3,HK2,PANK3,EPHA3,BTC,NEK10,RASAL2,IL15,MAPK4,NTRK3,CHUK,GRK6,PIBF1,DDR1,SPEG,TLR3,RPS6KL1,ALDOC,MYO3B,ACVR2A,DAB2IP,MET,IGFBP3,FER,MYLK3,GAPDH,PDK1,ADM2,PFKFB2,PTPN6,KCNH5,PANK1,FGF12,WNT11,PRKCQ,FRK,FGFR1,TPK1,SNCA,IRS2,PRKCB,PTK7,ABI3,BMPR1A,MAPK10,MAST1,TNIK,DYRK3,BMPR2,ENO2,GAS6,EPHB1,PKN1,INPP1,GHR,PRKCD,SGK3,PRKG2,SGK1,IQGAP3,SYK,FES,PFKFB4,RAPGEF2,NUAK2,OGDHL,AK4,RASA3,PEAK1,TRIB3,FGR,AKT3,MAP2K6,PGM2L1,NEK11,GRIN2D,PIP5KL1,HK1,BMP4,LRRK1,CMPK2,BTRC |
| 1.025e-02 | -4.58 | GO_GOLGI_MEMBRANE | MSigDB lists | GO_GOLGI_MEMBRANE | 667 | 84 | 17377 | 1707 |
LPCAT2,GALNT6,GALNT12,ATP8A1,XYLT1,MYO1B,RNF24,FAM198B,MGAT5B,CHST10,SLC9A7,TLR3,SEC16B,RAB26,TMED9,PROS1,COG3,CLVS2,RASGRP1,ATL1,CD55,ERGIC1,B3GALT1,GCNT2,WLS,TGFA,ARHGAP21,GBP1,ATP7B,TNFRSF1A,B3GALT2,DSEL,HS3ST3B1,RAB30,HACE1,UST,SEC24D,ST6GAL1,DHCR24,CLSTN2,GALNT13,CHSY1,NDFIP2,RAB11FIP5,GALNT1,GBGT1,FUT9,ABCA5,MGAT1,HS3ST5,SREBF1,LMAN2,ST8SIA1,FIG4,NCAM1,NOS3,B4GALT6,CHSY3,IL17RD,QSOX1,RHOQ,RAB6B,CYTH3,SYBU,MGAT4B,GPSM1,ST6GALNAC3,ARHGAP32,FNDC3A,B4GALNT3,GALNT14,GLCE,GALNT3,ICA1,SH3GL2,PMEPA1,RND3,ACER2,QPCTL,RAB31,PLD1,CERS1,B4GALT7,ABCG1 |
| 1.025e-02 | -4.58 | steroid metabolic process | biological process | GO:0008202 | 252 | 36 | 17256 | 1658 |
PRKAA2,TFCP2L1,MVK,LDLR,DHCR24,CYP4V2,STAT5B,CEBPA,CYP26A1,CYP51A1,IDI1,HMGCS1,ERG28,SOAT2,MSMO1,SREBF1,HMGCR,CYP1B1,EBPL,SLC27A2,MVD,CYB5R2,VLDLR,NFE2L1,NPC2,PLEKHA1,LEPR,FGFR1,INSIG1,SRD5A3,OSBPL5,SQLE,PPARGC1A,DHCR7,OSBPL6,ABCG1 |
| 1.027e-02 | -4.58 | protein dephosphorylation | biological process | GO:0006470 | 193 | 29 | 17256 | 1658 |
SSH3,PPP1R3D,DUSP8,PTPRD,PTPRU,PTPN13,PTPN6,UBASH3B,DNAJC6,PTPN21,PLPP2,DUSP9,LHPP,CTTNBP2NL,EYA4,PPP2R3A,PTPRC,PLPP1,PPM1E,PTPRJ,CDC14B,PALD1,DUSP19,PTPRS,PTPRN2,PPP2R2B,PTPRE,BTRC,DUSP1 |
| 1.028e-02 | -4.58 | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | MSigDB lists | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | 255 | 37 | 17377 | 1707 |
DOCK1,GALNT12,RUSC2,UBASH3B,ITGA6,EPS8,ADD2,COBLL1,ENAH,SNX9,CPNE2,HMGCS1,PMAIP1,FLRT3,ESD,PAK1,PHLDB2,ARAP2,KDM5B,TMEM43,CCNG1,TMEM47,PEAK1,CRYBG3,HOXA1,HOMER3,IRS2,PMEPA1,PLK2,KIAA0513,SQLE,SEMA3C,PLD1,TPM1,SPRED3,KIF1B,ABCG1 |
| 1.029e-02 | -4.58 | ATGTTAA,MIR-302C | MSigDB lists | ATGTTAA,MIR-302C | 230 | 34 | 17377 | 1707 |
ACVR1,PLEKHA5,ZCCHC24,MYO1B,CADM2,IL13RA1,CREB5,FOXG1,SIPA1L2,EHD3,PDE4D,FAM84B,MYT1,PTPRE,PCSK6,LCA5,MEIS2,FZD4,ADCY1,ST6GALNAC3,PHACTR2,ZFPM2,KHDRBS2,BCL11A,IRS2,KIAA0355,FCHO2,PPARGC1A,NEUROG2,PANK3,NR3C2,LIFR,CTNND2,FOXA1 |
| 1.029e-02 | -4.58 | PROVENZANI_METASTASIS_DN | MSigDB lists | PROVENZANI_METASTASIS_DN | 133 | 22 | 17377 | 1707 |
ST14,STXBP6,FOXN3,BLVRB,AK4,SPATS2L,RABAC1,F12,COTL1,GRK6,PFN2,SLCO3A1,CYP51A1,NELL2,DDAH1,P4HA2,SCRN1,PDE4D,TPM1,TBC1D4,IGFBP3,TPT1 |
| 1.029e-02 | -4.58 | GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP | MSigDB lists | GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP | 133 | 22 | 17377 | 1707 |
UST,COL6A2,DUSP8,FZD4,NR4A1,SYT12,LMCD1,FERMT2,ATF3,CEBPB,PPM1E,ID3,GSTO2,RND3,PLK2,OPN3,SGK1,ARL4D,FANK1,SPRY2,CEBPD,DUSP1 |
| 1.029e-02 | -4.58 | - | gene3d domains | 3.40.20.10 | 24 | 7 | 8148 | 867 |
SVIL,DBN1,GSN,COTL1,SEC24D,DSTN,SCIN |
| 1.030e-02 | -4.58 | GO_AXONAL_FASCICULATION | MSigDB lists | GO_AXONAL_FASCICULATION | 20 | 6 | 17377 | 1707 |
EPHA3,AMIGO1,CNTN4,NRP1,CELSR3,SEMA3A |
| 1.030e-02 | -4.58 | GO_M_BAND | MSigDB lists | GO_M_BAND | 20 | 6 | 17377 | 1707 |
OBSCN,MYOM2,ENO1,ANK2,ALDOA,FHL2 |
| 1.030e-02 | -4.58 | NIKOLSKY_BREAST_CANCER_15Q26_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_15Q26_AMPLICON | 20 | 6 | 17377 | 1707 |
ADAMTS17,CHSY1,LRRK1,IGF1R,ARRDC4,PCSK6 |
| 1.030e-02 | -4.58 | MODULE_58 | MSigDB lists | MODULE_58 | 20 | 6 | 17377 | 1707 |
CR2,C1R,CD55,CFH,CFHR1,C4BPB |
| 1.030e-02 | -4.58 | MOOTHA_GLYCOLYSIS | MSigDB lists | MOOTHA_GLYCOLYSIS | 20 | 6 | 17377 | 1707 |
HK1,ENO2,ENO1,PFKFB2,ALDOC,ALDOA |
| 1.030e-02 | -4.58 | GO_LYMPH_VESSEL_DEVELOPMENT | MSigDB lists | GO_LYMPH_VESSEL_DEVELOPMENT | 20 | 6 | 17377 | 1707 |
EFNB2,ACVR2B,BMPR2,CCBE1,SYK,HEG1 |
| 1.030e-02 | -4.58 | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | MSigDB lists | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_UP | 20 | 6 | 17377 | 1707 |
TRIM2,HOXB9,SLC39A8,VLDLR,LHX6,FOXA1 |
| 1.030e-02 | -4.58 | FERRARI_RESPONSE_TO_FENRETINIDE_UP | MSigDB lists | FERRARI_RESPONSE_TO_FENRETINIDE_UP | 20 | 6 | 17377 | 1707 |
SEMA3C,ATF3,HERPUD1,DDIT3,SLC7A5,DDIT4 |
| 1.030e-02 | -4.58 | AMIT_EGF_RESPONSE_240_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_240_MCF10A | 20 | 6 | 17377 | 1707 |
MICAL2,SLC7A11,INSIG1,TGFA,HERPUD1,PCDH7 |
| 1.035e-02 | -4.57 | nucleotide kinase activity | molecular function | GO:0019201 | 26 | 7 | 17224 | 1680 |
AK4,AK1,DLG2,CMPK2,MPP1,MAGI3,MPP2 |
| 1.036e-02 | -4.57 | GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN | MSigDB lists | GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN | 189 | 29 | 17377 | 1707 |
PLA2G4A,FARP1,RASAL2,ALOX5AP,AKAP5,SLC36A1,SLC39A8,EPS8,SELL,KCTD12,SCD,ABCC2,WNT11,GPSM2,TMEM47,GUCY1A2,LCP2,BMP6,PPP2R3A,CHST10,EEF2,MGAT1,XBP1,LRP6,NCAM1,PTPRE,GFI1,TTC39A,IGSF3 |
| 1.036e-02 | -4.57 | GSE41867_DAY6_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_DAY6_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | 189 | 29 | 17377 | 1707 |
ANTXR2,GPM6A,AVPI1,LCA5,USP2,GCAT,DNAJC3,RAPGEF4,MCTP2,MSRB3,PSD3,SAV1,UCHL3,CRYBG3,FKBP11,PYCR1,CCDC120,RPL28,WFS1,GAS2L3,SLC2A6,ZNF521,PRELID1,RGS10,TNFRSF17,TBC1D4,SFN,CKAP4,CTH |
| 1.036e-02 | -4.57 | GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | 189 | 29 | 17377 | 1707 |
CREB3L2,PAGE1,EHHADH,EDA2R,TGFA,PPFIBP2,LMCD1,MORC4,PDE8A,COL4A5,NHP2,PALLD,KBTBD11,IRS2,PDZD8,NACC2,TACC2,PELI2,FAT1,TECPR2,TSC22D1,BMP1,TUFT1,MYOM2,GRB10,TNFSF15,MARCKS,SPRY2,IGFBP3 |
| 1.036e-02 | -4.57 | GSE24726_WT_VS_E2-2_KO_PDC_DAY4_POST_DELETION_UP | MSigDB lists | GSE24726_WT_VS_E2-2_KO_PDC_DAY4_POST_DELETION_UP | 189 | 29 | 17377 | 1707 |
PLA2G4A,GCNT2,TTC39B,PTPRU,RAPGEF2,DNAJC3,PSTPIP2,AGPAT4,ATOX1,MAFB,IL13RA1,C1R,AIG1,CREB5,LACC1,CLN5,AARS,TRPS1,HPSE,AKAP7,KMO,SLC2A6,PRELID2,PLEKHG1,SVIL,SQLE,TANC2,SPRY2,CEBPD |
| 1.036e-02 | -4.57 | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP | MSigDB lists | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP | 189 | 29 | 17377 | 1707 |
ITGB7,TTC39B,SLC37A1,PNP,LGALS3,IL15,MCTP2,MCOLN3,SELL,GPSM2,CD40,HERC6,PLCB1,KBTBD11,INPP1,IL18R1,ISG20,HTR7,GPR15,CXCL10,TLR3,SETDB2,GYPC,GATA2,AKT3,GNB4,ALDH1L1,UACA,CMPK2 |
| 1.036e-02 | -4.57 | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP | MSigDB lists | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP | 189 | 29 | 17377 | 1707 |
EFNB2,EML5,BDNF,HBG2,ERGIC1,GCAT,FZD4,HEBP1,ATOX1,CEBPA,IL13RA1,PRDM1,HOXA1,RTN1,ID3,GALNT1,FGR,NAV1,NCKAP1L,PRKCD,PTPRS,DBP,TMEM37,IL1RAP,MID1,PDGFRB,CRYL1,B4GALT6,FZD1 |
| 1.036e-02 | -4.57 | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | 189 | 29 | 17377 | 1707 |
EXPH5,SH3BP2,ACVR1,TTC39B,ROBO2,PLEKHA8,CKAP2,REL,GDPD1,RNF125,LACC1,SMPDL3B,EPDR1,DOCK7,SLC7A11,SOAT2,ABCA5,PLOD2,PLXDC2,PCBP4,RBPMS2,P4HA2,SLC2A6,OPN3,SH3PXD2B,MBOAT2,PURG,MED12L,CES3 |
| 1.036e-02 | -4.57 | GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_COLON_TUMORAL_MACROPHAGE_UP | 189 | 29 | 17377 | 1707 |
ARHGAP26,GPR176,QSOX1,SH3BP2,FARP1,PTPN6,JDP2,LPCAT2,GALNT6,ELOVL3,PREX1,SPATA13,RASA3,CHSY1,COTL1,DOCK5,DOCK2,MSMO1,RPS11,SRD5A3,RGS10,RAI14,CERS4,FAR2,PTPRCAP,SERPINH1,SLC45A3,DOCK8,NUDT17 |
| 1.036e-02 | -4.57 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_UP | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_UP | 189 | 29 | 17377 | 1707 |
RIN2,GCNT2,TBC1D1,REL,FBXO4,PTPN13,FAM84A,LITAF,FHL2,PRICKLE1,KCTD12,SAV1,SATB1,ASPH,F3,ISG20,EBF1,SIPA1L2,PLAGL1,PIK3AP1,DACT1,TSPAN13,FIG4,MARCKS,ST8SIA1,GEM,CMPK2,NCAM1,RBMS2 |
| 1.036e-02 | -4.57 | GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | 189 | 29 | 17377 | 1707 |
ARHGAP26,MYCBP2,TBC1D1,HEBP1,DNAJC6,RAPGEF4,KCTD12,PRDM1,GABRR2,C3orf70,KIF21B,CD7,KREMEN1,PGAP1,ATP10D,CHST10,GSN,MAP2K6,RASGRF2,EHD3,SGK3,TNFRSF1A,RALGAPA2,SERPINI1,TSPAN13,DENND1C,PTPRE,RASGRP1,AMPD1 |
| 1.036e-02 | -4.57 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate | KEGG pathways | M00001 | 25 | 7 | 7161 | 730 |
HK1,GAPDH,ENO2,ENO1,ALDOC,ALDOA,HK2 |
| 1.036e-02 | -4.57 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate | KEGG pathways | hsa_M00001 | 25 | 7 | 7161 | 730 |
HK1,GAPDH,ENO2,ENO1,ALDOC,ALDOA,HK2 |
| 1.037e-02 | -4.57 | sensory perception of sound | biological process | GO:0007605 | 144 | 23 | 17256 | 1658 |
COL4A3,OTOGL,FZD4,GABRB2,GJB2,HOMER2,ROR1,SLC1A3,HOXA1,PGAP1,FGFR1,EYA4,GSDME,RIPOR2,ZNF354A,PDZD7,WFS1,MARVELD2,MYO3B,TFAP2A,MYO6,SPRY2,SNAI2 |
| 1.038e-02 | -4.57 | Cysteine biosynthesis, homocysteine + serine => cysteine | KEGG pathways | hsa_M00338 | 2 | 2 | 7161 | 730 |
CBS,CTH |
| 1.038e-02 | -4.57 | Cysteine biosynthesis, homocysteine + serine => cysteine | KEGG pathways | M00338 | 2 | 2 | 7161 | 730 |
CBS,CTH |
| 1.041e-02 | -4.56 | Acetylcholine regulates insulin secretion | REACTOME pathways | R-HSA-399997 | 10 | 4 | 10287 | 971 |
MARCKS,PRKCA,PLCB1,CHRM3 |
| 1.043e-02 | -4.56 | PTB | smart domains | SM00462 | 40 | 10 | 9493 | 1056 |
NUMBL,TBC1D1,EPS8,APBB1,TNS1,GULP1,APBA1,APBA2,TBC1D4,NOS1AP |
| 1.043e-02 | -4.56 | LamG | smart domains | SM00282 | 40 | 10 | 9493 | 1056 |
NELL2,CELSR1,FAT4,CELSR3,CNTNAP3,FAT1,PROS1,GAS6,NRXN1,SLIT2 |
| 1.044e-02 | -4.56 | PSI | pfam domains | PF01437 | 26 | 7 | 17054 | 1666 |
ATRNL1,SEMA6B,MET,SEMA4F,SEMA6A,PLXDC2,PLXNA2 |
| 1.044e-02 | -4.56 | negative regulation of ERK1 and ERK2 cascade | biological process | GO:0070373 | 67 | 13 | 17256 | 1658 |
CAMK2N1,CNKSR3,GBP1,C1QL4,NDRG2,DAB2IP,ATF3,SYNJ2BP,SPRY4,ERRFI1,TLR4,SPRY2,DUSP1 |
| 1.045e-02 | -4.56 | GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN | MSigDB lists | GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN | 181 | 28 | 17377 | 1707 |
TRDMT1,GDAP1,UNC5C,SLC3A2,USP2,TUBA1A,RUSC2,SLK,MYO1B,LMCD1,SORBS3,MFSD6,IL18R1,SEMA6A,GAS1,MAP1B,CEBPB,HTR7,RGS17,TYMP,AK1,GSN,TGFBR3,KIAA0355,CLMN,CYP2U1,MYO6,MYT1 |
| 1.045e-02 | -4.56 | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_DN | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_DN | 181 | 28 | 17377 | 1707 |
SUSD3,UST,ITGB7,BCL7A,EVL,MRC2,STAT4,TCEA3,ARL2,EFHC1,CCNG1,CTTNBP2NL,GAS6,ATP1B1,TGDS,SLC9A7,ZSCAN5A,NAV1,BACH2,UNC13B,RPS11,ABI3,GRIP1,LIMCH1,SP140,SPRY2,RASGRP1,SP140L |
| 1.045e-02 | -4.56 | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP | MSigDB lists | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP | 181 | 28 | 17377 | 1707 |
SERINC5,ACVR1,PDK1,ARHGEF11,KLHL3,ITGA6,ARID5B,MORC4,STAT5B,FAM13A,PRKCA,CRYBG3,RERE,BAG3,FRY,KIAA0355,INPP4B,SVIL,TRPC1,EPHB6,DBP,FHIT,ST8SIA1,RCAN3,TBC1D4,MAST4,MLLT3,PHC1 |
| 1.045e-02 | -4.56 | GSE7852_TREG_VS_TCONV_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_DN | 181 | 28 | 17377 | 1707 |
ANKRD13D,LANCL3,KLHL4,ELOVL7,DNAJC6,RAPGEF4,MCTP2,EDEM3,GABRG2,PRKCQ,NTRK3,NPC2,GRK6,ZFPM2,DENND3,INPP1,PGAP1,OTUD1,TGFBR3,SETDB2,SEMA4F,SLC30A4,EHD3,ITGB3,TNFRSF1A,SGK1,HS3ST3B1,DIRC2 |
| 1.045e-02 | -4.56 | PIGF_UP.V1_DN | MSigDB lists | PIGF_UP.V1_DN | 181 | 28 | 17377 | 1707 |
DLGAP1,PXN,ALOX5AP,PDE1B,KCNQ3,IGFBP6,PTPRU,NR6A1,HOMER2,DHCR24,MEF2B,OBSCN,AK4,COL18A1,CEBPA,KHDRBS2,FOXG1,NOS1AP,IQCK,NELL2,MAP1A,GYPC,PAIP2B,MCF2L,SLC6A15,NCAM1,ATP1A3,MAST1 |
| 1.045e-02 | -4.56 | GSE3982_BCELL_VS_TH2_DN | MSigDB lists | GSE3982_BCELL_VS_TH2_DN | 181 | 28 | 17377 | 1707 |
GPR63,TNIK,ANO10,BDNF,MRC2,KLHL23,MPP1,ATP9A,DHCR24,GATA3,RAB38,GUCY1A2,PALLD,NCS1,ZFYVE9,DCBLD2,SFXN1,SLC39A14,KAZN,DSG2,BMP1,INPP4B,MAP7,MAOA,GEM,TBC1D4,LIFR,LRP12 |
| 1.047e-02 | -4.56 | GO_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 32 | 8 | 17377 | 1707 |
GPR37,HGF,SESN2,MET,SESN1,LRRK2,SNCA,PYCR1 |
| 1.047e-02 | -4.56 | GO_ER_NUCLEUS_SIGNALING_PATHWAY | MSigDB lists | GO_ER_NUCLEUS_SIGNALING_PATHWAY | 32 | 8 | 17377 | 1707 |
ASNS,ATF4,INSIG1,WFS1,XBP1,ATF3,DDIT3,HERPUD1 |
| 1.047e-02 | -4.56 | JIANG_HYPOXIA_VIA_VHL | MSigDB lists | JIANG_HYPOXIA_VIA_VHL | 32 | 8 | 17377 | 1707 |
SLC3A2,ENO2,TES,RPL21,UACA,SPATS2L,CANX,CKAP4 |
| 1.047e-02 | -4.56 | PID_NETRIN_PATHWAY | MSigDB lists | PID_NETRIN_PATHWAY | 32 | 8 | 17377 | 1707 |
PAK1,AGAP2,UNC5C,UNC5B,DOCK1,MYO10,DCC,MAP1B |
| 1.048e-02 | -4.56 | V$PAX4_02 | MSigDB lists | V$PAX4_02 | 222 | 33 | 17377 | 1707 |
TYRO3,CGN,PCDH18,GABRB2,PTPN21,PLXNA2,PRDM8,IKZF2,TRPS1,FOXP2,EOMES,RALGPS2,BACE2,CHRDL1,MARCKS,ETV1,ZFP36L2,NKX2-1,RHOQ,MEIS2,MSX1,TBC1D8B,NFIA,MBNL2,NAALADL2,MAP1B,ZIC1,TMEM154,IKZF3,LAMB1,SEMA3C,SEMA3A,SFN |
| 1.050e-02 | -4.56 | GO_BONE_DEVELOPMENT | MSigDB lists | GO_BONE_DEVELOPMENT | 149 | 24 | 17377 | 1707 |
MSX1,INPPL1,RUNX2,SMAD9,BMPR2,PTPN6,DCHS1,CHSY1,BMP6,COL27A1,SKI,PLS3,PTPRC,FAT4,INSIG1,TFAP2A,SH3PXD2B,LRRK1,BMP4,SERPINH1,SHOX2,MMP16,ZNF385A,MEF2C |
| 1.051e-02 | -4.56 | GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_UP | MSigDB lists | GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_UP | 173 | 27 | 17377 | 1707 |
PLA2G4A,CHSY3,CDH26,GPM6A,CACNG3,PRSS12,CKAP2,PARD3B,ZCCHC24,UBASH3B,PTPN13,MGAT4B,EFHC2,ADAMTS6,ITPR2,PALLD,TTC28,TIAM2,PLS3,RPS6KA2,TGFBR3,FUT9,RCAN3,RNF148,TSPAN9,PRKACB,IGSF3 |
| 1.051e-02 | -4.56 | GSE14000_4H_VS_16H_LPS_DC_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_UP | 173 | 27 | 17377 | 1707 |
PLA2G4A,SV2B,GPM6A,GARS,EVL,SKAP2,MPP1,UBASH3B,BLVRB,VAMP8,FAM198B,ATP1B1,SLC46A3,QPRT,GALNT1,TMEM154,RPS11,NCOA7,MORN2,KLF9,RNF130,RPS12,NRP1,IL1RAP,PANK3,CRYL1,RPS13 |
| 1.051e-02 | -4.56 | V$OSF2_Q6 | MSigDB lists | V$OSF2_Q6 | 247 | 36 | 17377 | 1707 |
CXCR5,SLC6A9,RUNX2,OTOGL,REL,RNF24,CHSY1,SPINK5,DACH2,TSPAN17,PRRG4,GPR15,CHN1,ZNF362,KCTD15,STC2,TMEM86A,BCL6,TSC22D1,SGK1,NCAM1,NKX2-1,DPYSL5,RHOQ,SMAD9,AGPAT4,FERMT2,FGFR1,ZIC1,DKK1,DYRK1B,DLX2,RNF122,PURG,PCSK5,HEY1 |
| 1.054e-02 | -4.55 | GSE25677_MPL_VS_R848_STIM_BCELL_DN | MSigDB lists | GSE25677_MPL_VS_R848_STIM_BCELL_DN | 165 | 26 | 17377 | 1707 |
ARHGAP26,ITGB7,CARD6,CD55,TUBA1A,RNF144A,STAT4,XYLT1,SELL,RASA3,VIM,ADAMTS6,ATP1B1,KIF21B,SNX9,SATB1,PGAP1,DEXI,ENPP1,MYADM,FRY,BACH2,AKT3,FAM107B,BCL6,MEF2C |
| 1.054e-02 | -4.55 | GSE25677_MPL_VS_R848_STIM_BCELL_UP | MSigDB lists | GSE25677_MPL_VS_R848_STIM_BCELL_UP | 165 | 26 | 17377 | 1707 |
RPS20,MYCBP2,TSPAN15,LPCAT2,CACNA1E,MCOLN3,TMTC4,CR2,PDE8A,PRDM1,ITPR2,PLEKHA1,ZDHHC14,NEDD4,TLR3,PTPRJ,ASNS,MYC,RUNDC3B,RGS10,CDH17,INPP5F,MARCKS,PDE4D,TBC1D9,IL9R |
| 1.054e-02 | -4.55 | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | 165 | 26 | 17377 | 1707 |
MSX1,KCNIP3,NKX3-2,JDP2,ARID5B,GATA3,BCL6B,ATF3,PRDM1,ZFPM2,ZNF219,SATB1,BATF3,BCL11A,NKX6-1,FOXP2,MSC,BACH2,KLF12,NACC2,BCL6,TFAP2A,ZBTB20,GFI1,GLIS1,SNAI2 |
| 1.054e-02 | -4.55 | VANTVEER_BREAST_CANCER_ESR1_UP | MSigDB lists | VANTVEER_BREAST_CANCER_ESR1_UP | 157 | 25 | 17377 | 1707 |
SUSD3,MAN2B2,VAV3,EVL,CELSR1,SCAMP1,C4A,SYBU,PREX1,GATA3,BTBD9,ABAT,OVOL2,NPDC1,FAM174B,C9orf116,PPP1R26,XBP1,SREBF1,TSPAN13,TBC1D9,MAST4,GFRA1,FOXA1,PCSK6 |
| 1.054e-02 | -4.55 | GSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_DN | MSigDB lists | GSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_DN | 157 | 25 | 17377 | 1707 |
TRDMT1,BCL11B,DBN1,GXYLT2,ALDH2,GLIPR1L1,UBASH3B,CHSY1,KIAA1217,PALLD,CENPV,BATF3,CCNJ,GJC1,INHBC,IFT81,GPRIN1,LRRN1,SLC7A11,PELI2,PDE10A,OSBPL5,CTTN,ATP6AP1L,FZD1 |
| 1.055e-02 | -4.55 | Mucin type O-glycan biosynthesis | KEGG pathways | ko00512 | 31 | 8 | 7161 | 730 |
GALNT3,GALNT17,GALNT1,GALNT13,GALNT14,GALNT18,GALNT6,GALNT12 |
| 1.055e-02 | -4.55 | Mucin type O-glycan biosynthesis | KEGG pathways | hsa00512 | 31 | 8 | 7161 | 730 |
GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT18,GALNT14 |
| 1.058e-02 | -4.55 | Plexin_repeat | interpro domains | IPR002165 | 26 | 7 | 18492 | 1811 |
ATRNL1,SEMA6B,MET,SEMA4F,PLXDC2,SEMA6A,PLXNA2 |
| 1.058e-02 | -4.55 | Kringle-like | interpro domains | IPR013806 | 26 | 7 | 18492 | 1811 |
HGF,ROR1,MRC2,F12,FN1,PRSS12,KREMEN1 |
| 1.058e-02 | -4.55 | GO_PHOSPHOLIPID_TRANSPORTER_ACTIVITY | MSigDB lists | GO_PHOSPHOLIPID_TRANSPORTER_ACTIVITY | 45 | 10 | 17377 | 1707 |
PLSCR4,ATP9A,MFSD2A,ATP8A1,OSBPL5,PRELID2,PRELID1,ATP11A,ATP10D,ABCG1 |
| 1.058e-02 | -4.55 | GO_SCAFFOLD_PROTEIN_BINDING | MSigDB lists | GO_SCAFFOLD_PROTEIN_BINDING | 45 | 10 | 17377 | 1707 |
SCN5A,LRP4,NLGN4X,CHUK,VIM,PDE4D,P2RY1,DSP,ATP2B4,NOS3 |
| 1.058e-02 | -4.55 | SILIGAN_BOUND_BY_EWS_FLT1_FUSION | MSigDB lists | SILIGAN_BOUND_BY_EWS_FLT1_FUSION | 45 | 10 | 17377 | 1707 |
KCNAB1,PTPRD,PDE10A,ADCY1,GRID1,FHIT,ZBBX,NEO1,HEY1,HS6ST3 |
| 1.058e-02 | -4.55 | GO_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS | MSigDB lists | GO_EMBRYONIC_CRANIAL_SKELETON_MORPHOGENESIS | 45 | 10 | 17377 | 1707 |
SMAD3,RUNX2,WDR19,TFAP2A,DLX2,BMP4,MMP16,HOXA1,SIX2,MEF2C |
| 1.058e-02 | -4.55 | GO_T_TUBULE | MSigDB lists | GO_T_TUBULE | 45 | 10 | 17377 | 1707 |
SCN5A,KCNN2,SCN1B,CACNB2,ANK2,AHNAK2,SCN2A,CACNA2D1,NOS1AP,ATP2B4 |
| 1.058e-02 | -4.55 | ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF | MSigDB lists | ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF | 45 | 10 | 17377 | 1707 |
SPOCD1,FHDC1,RNF24,KLF5,PAX9,ERRFI1,JAM2,LIFR,CCNJ,F3 |
| 1.059e-02 | -4.55 | regulation of MAP kinase activity | biological process | GO:0043405 | 348 | 47 | 17256 | 1658 |
TENM1,TNIK,NEK10,AVPI1,DUSP8,FZD8,NTRK3,PKN1,TPD52L1,STK24,IGF1R,PRKCD,GHR,INAVA,DAB2IP,IQGAP3,TLR4,TNFRSF11A,SYK,SPRY2,PDGFRB,RASGRP1,HMGCR,DUSP1,PAK1,FZD4,PTPN6,TGFA,LRRK2,DUSP9,CD40,TLR6,FGFR1,DKK1,MAPKAPK2,TRIB3,PTPRJ,MAP2K6,ERN1,MAP3K21,DUSP19,HGF,DIRAS1,BMP4,SPRY4,MAPK10,MAP3K20 |
| 1.059e-02 | -4.55 | Ca2+ pathway | REACTOME pathways | R-HSA-4086398 | 61 | 12 | 10287 | 971 |
GNG12,TCF7L1,FZD4,GNB4,GNAO1,PRKG1,PRKG2,AGO4,WNT11,ITPR2,PRKCA,PLCB1 |
| 1.063e-02 | -4.54 | ATAGGAA,MIR-202 | MSigDB lists | ATAGGAA,MIR-202 | 95 | 17 | 17377 | 1707 |
STOX2,EIF4E3,ACVR1,ROBO2,ENAH,CTBP2,PLEKHA1,KHDRBS2,PGAP1,BCL11A,ZNF362,HLF,KLF12,PCGF2,KIAA0408,MARCKS,ATP2B4 |
| 1.063e-02 | -4.54 | GO_STRIATED_MUSCLE_CONTRACTION | MSigDB lists | GO_STRIATED_MUSCLE_CONTRACTION | 95 | 17 | 17377 | 1707 |
SCN5A,ARHGEF11,ANK2,FGF12,PKP2,RYR2,CHUK,ATP1B1,GJC1,EEF2,SCN1B,MAP2K6,CACNB2,ALDOA,TPM1,CACNA2D1,ATP1A3 |
| 1.067e-02 | -4.54 | endoplasmic reticulum membrane | cellular component | GO:0005789 | 1045 | 121 | 18223 | 1724 |
CREB3L2,PLA2G4A,ACSL1,ELOVL4,LPCAT2,DNAJC3,XYLT1,ITPR2,SEZ6L2,LPIN3,CANX,ABHD4,CYP26A1,NOS1AP,CDS1,RTN1,CYP51A1,ERG28,TLR3,PDZD8,SEC16B,ERO1B,SLC10A7,ZDHHC6,REEP1,TMED9,PROS1,RASGRP1,ALG10B,CYP1B1,ATL1,ANTXR2,TMEM67,EVA1A,ERGIC1,EBPL,LRRC8B,WLS,TGFA,CYB5R2,C3orf52,JPH1,LRMP,TRAM1L1,HACD1,NFE2L1,RNF125,TRIQK,ASPH,ATP10D,GJC1,INSIG1,RASGRF2,PEMT,WFS1,ERN1,ALG11,CYP2U1,MBOAT2,NR3C2,RETREG1,TYRO3,ALOX5AP,CLGN,SEC24D,CYP2J2,ELOVL7,DHCR24,CYP4V2,UBAC2,CLSTN2,SCD,SPINK5,PGAP1,MYORG,RNF180,GALNT1,BNIP1,SOAT2,MSMO1,FLRT3,SREBF1,SGK1,LMAN2,CERS4,NCEH1,MOXD1,TESPA1,CKAP4,HMGCR,FADS1,B3GLCT,SLC37A1,RNF170,SLC27A2,MGST3,AGPAT4,ELOVL3,GPSM1,RYR2,SHISA2,ARHGAP32,ILDR2,LRAT,HERPUD1,GPR37,EDA,PLOD2,FMO4,MFSD2A,OSBPL5,XBP1,SRD5A3,SQLE,MYRF,PLD1,CERS1,DHCR7,PTGES,OSBPL6,ABCG1 |
| 1.071e-02 | -4.54 | alpha-amino acid biosynthetic process | biological process | GO:1901607 | 60 | 12 | 17256 | 1658 |
SERINC5,ASNS,PLOD2,AASS,CBS,ASS1,SLC1A3,PHGDH,GATM,PSPH,PYCR1,CTH |
| 1.073e-02 | -4.53 | GO_REGULATION_OF_DEVELOPMENTAL_GROWTH | MSigDB lists | GO_REGULATION_OF_DEVELOPMENTAL_GROWTH | 281 | 40 | 17377 | 1707 |
LATS2,SEMA6B,FN1,BMPR2,FGF13,PLXNA2,STAT5B,NTRK3,SEMA6A,PPP2R3A,HOPX,NKX6-1,RND2,SEMA4F,GHR,STC2,CTTN,WWC2,RIMS2,SEMA6C,DISC1,BDNF,MSTN,DCC,WWC1,YAP1,PLS1,SAV1,PLCB1,FGFR1,MAP1B,BCL11A,CSF1,ADRB1,SEMA3C,BMP4,NRP1,SEMA3A,MEF2C,TLL2 |
| 1.074e-02 | -4.53 | V$PAX4_03 | MSigDB lists | V$PAX4_03 | 239 | 35 | 17377 | 1707 |
PHACTR3,MXI1,PCSK1N,ANKRD13B,DUSP8,FLVCR2,BCL6B,ZIC2,SEMA6A,FOXP2,TUBB4A,MAP1A,KCNN2,PCBP4,ZIC5,ST8SIA1,POU3F3,NKX2-1,PAK1,ANK2,PRDM13,NFE2L1,PRKAR2B,PRDM1,ACVR2B,PLCB1,FGFR1,MAP1B,BCL11A,MSC,GNAO1,ABI3,SERPINI1,HOXB9,HS6ST3 |
| 1.075e-02 | -4.53 | GO_EXOCYTOSIS | MSigDB lists | GO_EXOCYTOSIS | 298 | 42 | 17377 | 1707 |
DOC2A,FN1,STXBP5L,SCAMP1,PRSS12,SYT12,VAMP8,GAS6,SYT14,PCLO,ARHGAP44,PCDH7,SCIN,RAB11FIP5,UNC13B,GATA2,ITGB3,RAB26,SCRN1,LIN7A,CADPS2,PROS1,STXBP1,SYK,RASGRP1,RIMS2,VEGFC,PAK1,QSOX1,ABCC4,EXOC6B,RAPGEF4,PHACTR2,SNAP25,RARRES2,TRIM9,ALDOA,RAB31,HGF,SEPT5,TC2N,SNPH |
| 1.075e-02 | -4.53 | atrial cardiac muscle cell to AV node cell communication | biological process | GO:0086066 | 15 | 5 | 17256 | 1658 |
SCN5A,KCNN2,CACNB2,ANK2,GJC1 |
| 1.075e-02 | -4.53 | cell migration involved in sprouting angiogenesis | biological process | GO:0002042 | 15 | 5 | 17256 | 1658 |
EFNB2,NRP1,NR4A1,SLIT2,GPLD1 |
| 1.075e-02 | -4.53 | venous blood vessel development | biological process | GO:0060841 | 15 | 5 | 17256 | 1658 |
SEMA3C,ACVR2B,BMPR2,CCBE1,HEG1 |
| 1.075e-02 | -4.53 | cell communication by electrical coupling involved in cardiac conduction | biological process | GO:0086064 | 15 | 5 | 17256 | 1658 |
RYR2,PKP2,ATP1B1,ATP1A3,GJC1 |
| 1.075e-02 | -4.53 | heart trabecula formation | biological process | GO:0060347 | 15 | 5 | 17256 | 1658 |
OVOL2,TGFBR3,ADGRG6,HEY1,FHL2 |
| 1.075e-02 | -4.53 | GO_DESMOSOME | MSigDB lists | GO_DESMOSOME | 26 | 7 | 17377 | 1707 |
POF1B,PKP2,DSP,JAM3,KAZN,DSG2,PERP |
| 1.075e-02 | -4.53 | BRACHAT_RESPONSE_TO_METHOTREXATE_DN | MSigDB lists | BRACHAT_RESPONSE_TO_METHOTREXATE_DN | 26 | 7 | 17377 | 1707 |
AK4,HMGCS1,GAPDH,ENO1,EMILIN2,ALDOA,BNIP3L |
| 1.075e-02 | -4.53 | REACTOME_GLYCOLYSIS | MSigDB lists | REACTOME_GLYCOLYSIS | 26 | 7 | 17377 | 1707 |
PFKFB4,GAPDH,ENO2,ENO1,PFKFB2,ALDOC,ALDOA |
| 1.075e-02 | -4.53 | GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 26 | 7 | 17377 | 1707 |
VEGFC,GRB10,DAB2IP,PRKCB,FZD4,NEDD4,ITGB3 |
| 1.075e-02 | -4.53 | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 26 | 7 | 17377 | 1707 |
BBC3,PMAIP1,WFS1,XBP1,HERPUD1,DDIT3,LRRK2 |
| 1.075e-02 | -4.53 | GNF2_TM4SF2 | MSigDB lists | GNF2_TM4SF2 | 26 | 7 | 17377 | 1707 |
SV2B,SNAP25,SH3GL2,STXBP1,GNAO1,HPCAL4,PGBD5 |
| 1.075e-02 | -4.53 | MODULE_59 | MSigDB lists | MODULE_59 | 26 | 7 | 17377 | 1707 |
THOC5,ITPR2,MSTN,FUT9,PPFIA2,BMP6,RAPGEF4 |
| 1.075e-02 | -4.53 | VALK_AML_CLUSTER_2 | MSigDB lists | VALK_AML_CLUSTER_2 | 26 | 7 | 17377 | 1707 |
PLA2G4A,LAPTM4B,PLS1,GRB10,TRIM16,DOCK1,ARHGAP22 |
| 1.075e-02 | -4.53 | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | MSigDB lists | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_UP | 26 | 7 | 17377 | 1707 |
RUNX2,FGFR1,BTRC,PDGFRB,TNFRSF1A,IGFBP3,BCL6 |
| 1.075e-02 | -4.53 | Rho protein signal transduction | biological process | GO:0007266 | 82 | 15 | 17256 | 1658 |
PAK1,RND2,RHOQ,CELSR1,RND3,ARHGEF11,RHOBTB1,RHOD,PAK5,EPS8,BCL6,CHUK,SYNJ2BP,RAC3,SHTN1 |
| 1.075e-02 | -4.53 | GO_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | MSigDB lists | GO_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | 73 | 14 | 17377 | 1707 |
BCL11B,ENAM,SCN5A,MSX1,RUNX2,CA2,ITGA6,LRP4,LRP6,ACVR2B,DLX2,BMP4,BMPR1A,PERP |
| 1.075e-02 | -4.53 | MODULE_139 | MSigDB lists | MODULE_139 | 73 | 14 | 17377 | 1707 |
EPCAM,DPYSL5,GCA,VAV3,ICA1,SYT12,GPR160,BLVRB,RAB26,GATA3,MYO6,FOXA1,OCLN,TRPS1 |
| 1.075e-02 | -4.53 | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 73 | 14 | 17377 | 1707 |
MAPKAPK2,VEGFC,VAV3,PXN,BMPR2,NCKAP1L,DOCK1,SH2D2A,ITGB3,XBP1,MAPK13,DAB2IP,NRP1,BAIAP2 |
| 1.076e-02 | -4.53 | Effects of PIP2 hydrolysis | REACTOME pathways | R-HSA-114508 | 27 | 7 | 10287 | 971 |
DAGLA,PRKCQ,ITPR2,TRPC3,ABHD6,RASGRP1,PRKCD |
| 1.078e-02 | -4.53 | GRB10 (growth factor receptor bound protein 10) | protein interactions | 2887 | 44 | 10 | 17029 | 1718 |
IRS2,IGF1R,GHR,HECW2,RCAN3,EPHB1,BAIAP2,PDGFRB,NEDD4,DENND5B |
| 1.078e-02 | -4.53 | BATF3 (basic leucine zipper ATF-like transcription factor 3) | protein interactions | 55509 | 44 | 10 | 17029 | 1718 |
CARS,ATF4,BACH2,ATF3,CEBPA,CREB5,DBP,BATF,DDIT3,BATF3 |
| 1.079e-02 | -4.53 | RB_DN.V1_DN | MSigDB lists | RB_DN.V1_DN | 118 | 20 | 17377 | 1707 |
CREB3L2,MICAL2,CELSR1,UROS,GJB2,PLXNA2,COL18A1,RASL11B,CHAC1,DDIT4,MYADM,MSMO1,STC2,SLC7A5,SQLE,P4HA1,MOXD1,LIFR,DDIT3,IGFBP3 |
| 1.081e-02 | -4.53 | regulation of action potential | biological process | GO:0098900 | 53 | 11 | 17256 | 1658 |
TRPM4,SCN5A,FGF13,ANK2,DSG2,FGF12,PKP2,RYR2,DSP,CACNA2D1,NOS1AP |
| 1.081e-02 | -4.53 | negative regulation of actin filament polymerization | biological process | GO:0030837 | 53 | 11 | 17256 | 1658 |
GSN,MYADM,TMSB15A,PRKCD,EPS8,ADD2,TMOD2,PFN2,SLIT2,FHOD3,SCIN |
| 1.084e-02 | -4.52 | GPCR_2-like | interpro domains | IPR017981 | 59 | 12 | 18492 | 1811 |
ADGRB3,CELSR1,CELSR3,FZD4,FZD8,ADGRL1,CALCRL,ADGRA3,ADGRL2,ADGRG6,ADGRB2,FZD1 |
| 1.086e-02 | -4.52 | organic hydroxy compound biosynthetic process | biological process | GO:1901617 | 169 | 26 | 17256 | 1658 |
PRKAA2,MVK,SLC27A2,CYB5R2,MVD,DHCR24,GATA3,ISYNA1,SNCA,CYP51A1,GPR37,IDI1,ERG28,HMGCS1,INSIG1,MSMO1,ACER2,SRD5A3,TRPC1,SQLE,PCK2,MOXD1,DHCR7,PLTP,OSBPL6,HMGCR |
| 1.088e-02 | -4.52 | rhythmic process | biological process | GO:0048511 | 253 | 36 | 17256 | 1658 |
PRKAA2,TYRO3,ID1,LGR4,ROBO2,HEBP1,ASS1,STAT5B,BTBD9,NTRK3,SREBF1,KLF9,TNFRSF11A,SLIT2,NOS3,NKX2-1,GPR176,USP2,ATF4,KDM5B,MSTN,FZD4,ADCY1,PLEKHA1,RACK1,HTR7,ID3,HLF,MAP2K6,PAM,CIART,DBP,OXTR,PPARGC1A,MAPK10,BTRC |
| 1.088e-02 | -4.52 | GO_ENZYME_REGULATOR_ACTIVITY | MSigDB lists | GO_ENZYME_REGULATOR_ACTIVITY | 906 | 110 | 17377 | 1707 |
ARHGAP26,PHACTR3,PCSK1N,PPP4R4,RASAL2,FGF13,DOCK1,RECK,C4A,DNAJC3,ARHGAP22,RGS20,NPM1,FAM13A,DOCK2,TBC1D30,TIAM2,TBC1D19,SKI,ADPRHL1,BAG3,SIPA1L2,PPP1R26,DAB2IP,PROS1,PCOLCE2,PPP2R2B,SERPINH1,RCAN3,SLIT2,IGFBP3,TBC1D8,TNK2,COL4A3,CSN2,LRRK2,PREX1,ELMOD1,PRKAR2B,WNT11,ATP1B1,TBC1D16,SNCA,CAMK2N1,ARHGAP21,CXCL10,NRG3,GPRC5B,NCKAP1L,RGS10,DUSP19,ARHGAP28,SERPINI1,SPOCK3,RGS16,ALOX5AP,STXBP5L,FN1,ARHGEF11,TBC1D1,IPO5,OPHN1,ARL2,GAS6,GPSM2,RGS7,PFN2,SPINK5,GRPEL2,PPP2R3A,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,FRY,FLRT3,PRKCD,SRGAP1,RALGAPA2,LRP6,AFAP1L2,IQGAP3,TBC1D9,ERRFI1,SPRY2,MOB1B,VAV3,RIN2,ARAP2,TBC1D8B,CRIM1,RAPGEF2,ASAP3,GPSM1,RASA3,PHACTR2,AGAP2,ARHGAP32,PLCB1,TBC1D2,MMP15,TRIB3,SH3BP4,TBC1D4,TESC,MMP16,SFN,ATP2B4,PKIA |
| 1.088e-02 | -4.52 | GO_NUCLEIC_ACID_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_NUCLEIC_ACID_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 1147 | 136 | 17377 | 1707 |
GATA3,CEBPA,STAT5B,IKZF2,DACH2,TRPS1,EOMES,IKZF5,GRHL1,DLX6,SP140,ENO1,ETV1,POU3F3,NKX2-1,ZNF391,MEIS2,KCNIP3,ATF4,SMAD9,NR6A1,NFIA,ZNF565,NFE2L1,MEF2B,BATF,TCF7L1,HLF,KLF12,ZBTB20,DLX2,LZTS1,MEF2C,BCL11B,RUNX2,ZHX3,JDP2,GTF2IRD1,ZNF215,ZIC2,FOXG1,SATB1,MECOM,KIAA1958,ZBTB38,ZNF354A,GATA2,MYC,SREBF1,EBF4,GLIS1,ZNF518B,BARX1,CEBPD,ZNF629,RAX,STAT4,ARID5B,ZNF605,MAFB,PRDM1,TAF4B,PLAGL1,HEYL,HOXD13,NKX2-8,SIX2,TFCP2L1,CREB3L2,ID1,ZNF516,ZNF311,OTX1,BCL6B,ZSCAN5A,ZNF438,POU5F1B,LHX6,BCL6,POU2F2,MYT1,SNAI2,GLI1,SOX21,NKX3-2,ATF3,ATOH1,BCL11A,BATF3,ZNF711,ZNF396,SMAD3,ZNF93,MSC,IKZF3,BACH2,KLF5,BMPR1A,DBP,NR3C2,HEY1,REL,PLAG1,OVOL2,CREB5,ZNF219,NKX6-1,FOXP2,BHLHA15,TSC22D1,TFAP2A,KLF9,SMAD6,GFI1,ZFP36L2,MSX1,KDM5B,HNF4G,NR4A1,FOXN3,ESRRG,ZFPM2,RERE,ZIC1,EBF1,CEBPB,ID3,NACC2,L3MBTL4,XBP1,PCGF2,ZNF808,PAX9,DDIT3,FOXA1,ZNF235 |
| 1.089e-02 | -4.52 | purine ribonucleotide binding | molecular function | GO:0032555 | 1840 | 208 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,RPS6KA2,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 |
| 1.090e-02 | -4.52 | ruffle membrane | cellular component | GO:0032587 | 91 | 16 | 18223 | 1724 |
EPB41L5,PAK1,EPS8,SPATA13,WWC1,PSD3,PLEKHA1,PTPRJ,FGR,ITGB3,SPRY4,TPM1,MYO6,PACSIN1,TESC,SPRY2 |
| 1.091e-02 | -4.52 | GO_ORGANIC_ANION_TRANSPORT | MSigDB lists | GO_ORGANIC_ANION_TRANSPORT | 367 | 50 | 17377 | 1707 |
PLA2G4A,PRKAA2,SERINC5,ACSL1,SLC6A9,ATP9A,ATP8A1,LDLR,SLC36A4,SLC1A3,SLC7A2,APBA1,CACNB4,SLCO3A1,SLC19A2,UNC13B,CA2,SLC22A17,SLC7A11,SLC16A2,PPFIA2,PRELID2,FABP6,PRELID1,SERINC2,SLC6A15,SLC16A9,SLCO4C1,STXBP1,SLC3A2,ABCC4,SLC36A1,SLC27A2,CYB5R2,ABCC2,ATP11A,SNAP25,NPC2,ATP10D,CA13,SLC7A1,MFSD2A,OSBPL5,SLC7A5,SH3BP4,SLCO5A1,SLC1A5,SLC16A10,SLC43A1,ABCG1 |
| 1.092e-02 | -4.52 | PILON_KLF1_TARGETS_UP | MSigDB lists | PILON_KLF1_TARGETS_UP | 472 | 62 | 17377 | 1707 |
CGN,SV2B,AMOTL1,FN1,DUSP8,PTPRD,PLXNA2,MSR1,COL18A1,NDRG2,HBE1,SPATS2L,COL14A1,FOXP2,TGFBR3,HMGCS1,IGF1R,ALDOC,GHR,BNIP3,LOXL4,CTTN,SERPINH1,TSPAN9,TMEM56,IGSF3,FZD1,EPB41L5,TMC7,HBG2,COL6A2,SLC27A2,SLC39A8,CAP2,DUSP9,WWC1,FERMT2,PLS1,WNT11,PRKAR2B,SNTB1,EXOG,ASPH,GPC6,DCBLD2,SNCA,IRS2,CAMK2N1,ZNF266,PLAGL1,KIAA0355,WDR19,TUFT1,GRB10,HS3ST3B1,TTC39A,MBOAT2,CDH2,RNF157,MLLT3,STON2,LPP |
| 1.096e-02 | -4.51 | V$P300_01 | MSigDB lists | V$P300_01 | 231 | 34 | 17377 | 1707 |
ZNF395,HEBP1,CTBP2,EPHB1,CANX,DDIT4,HMGCS1,CACNB2,LHX6,MPPED2,TRIM3,RBMS2,PRKACB,SKAP2,CRIM1,GJB2,ESRRG,PRDM13,PREX1,FGF12,PRRG1,SLITRK5,WNT11,TMEM47,FGFR1,BCL11A,RERE,ZIC1,GPLD1,GSN,TNFRSF1A,NXPH4,SERPINI1,FNBP1L |
| 1.097e-02 | -4.51 | ROVERSI_GLIOMA_COPY_NUMBER_DN | MSigDB lists | ROVERSI_GLIOMA_COPY_NUMBER_DN | 52 | 11 | 17377 | 1707 |
GPR63,CPNE2,UROS,DOCK1,GNAO1,PRDM13,CTBP2,FANK1,PTPRE,HERPUD1,DHX32 |
| 1.097e-02 | -4.51 | VANTVEER_BREAST_CANCER_METASTASIS_UP | MSigDB lists | VANTVEER_BREAST_CANCER_METASTASIS_UP | 52 | 11 | 17377 | 1707 |
EVL,ERGIC1,EBF4,GSTM3,BBC3,TBC1D9,KIAA1217,RAB27B,MYRIP,NEO1,PCSK6 |
| 1.097e-02 | -4.51 | GO_VENTRICULAR_SEPTUM_DEVELOPMENT | MSigDB lists | GO_VENTRICULAR_SEPTUM_DEVELOPMENT | 52 | 11 | 17377 | 1707 |
PTK7,HEYL,GATA3,WNT11,PRDM1,SAV1,ZFPM2,SMAD6,FZD1,HEY1,HEG1 |
| 1.097e-02 | -4.51 | REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE | MSigDB lists | REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE | 52 | 11 | 17377 | 1707 |
FGFR4,PDE1B,PRKCD,ADCY1,ADCY6,PRKAR2B,FGF17,ITPR2,PRKCA,PRKACB,FGFR1 |
| 1.097e-02 | -4.51 | GO_SH3_SH2_ADAPTOR_ACTIVITY | MSigDB lists | GO_SH3_SH2_ADAPTOR_ACTIVITY | 52 | 11 | 17377 | 1707 |
CHN1,VAV3,CHN2,SORBS1,SH3BP2,SKAP2,SH2D2A,GRB14,EPS8,GRB10,SKAP1 |
| 1.099e-02 | -4.51 | GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION | MSigDB lists | GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION | 66 | 13 | 17377 | 1707 |
TRPM4,SCN5A,GSTM2,ANK2,DSG2,PKP2,RYR2,GSTO1,PDE4D,ATP1B1,ASPH,DSP,NOS1AP |
| 1.099e-02 | -4.51 | ACAACTT,MIR-382 | MSigDB lists | ACAACTT,MIR-382 | 66 | 13 | 17377 | 1707 |
BCL11B,BDNF,ACVR1,NFIA,NDRG2,SGK1,HS3ST3B1,MBNL2,MMP16,HSPA2,ATP2B1,NEGR1,MTUS1 |
| 1.101e-02 | -4.51 | S_TKc | smart domains | SM00220 | 349 | 53 | 9493 | 1056 |
PRKAA2,TNIK,LATS2,ACVR1,DYRK3,SLK,CHUK,MAPK4,GRK6,PRKCA,PKN1,STK24,MOK,SPEG,RPS6KA2,PRKCD,SGK3,PRKG1,MYO3B,ACVR2A,PRKG2,SGK1,MAST4,PRKACB,PAK1,MYLK3,MARK1,ACVR1C,LRRK2,NUAK2,OBSCN,PRKCQ,CDC42BPA,SGK2,PEAK1,GRK3,DYRK1B,MAPKAPK2,TRIB3,PRKCB,PKN3,MAP2K6,AKT3,PLK2,ERN1,MAP3K21,NEK11,MAPK13,LRRK1,BMPR1A,MAPK10,MAP3K20,MAST1 |
| 1.102e-02 | -4.51 | response to organonitrogen compound | biological process | GO:0010243 | 889 | 106 | 17256 | 1658 |
PRKN,SORBS1,ID1,PDE1B,TRIM16,LDLR,ASS1,CHUK,STAT5B,ITPR2,ABAT,ASNS,TGFBR3,PDE4D,TLR4,TSHR,SLIT2,PRKACB,GLDC,TRDMT1,FER,TMEM67,SESN2,ATF4,UROS,ACVR1C,LRRK2,ADCY1,PRKAR2B,ABCC2,CD40,SESN1,SNCA,GNAI1,IRS2,GSN,ENPP1,EIF4EBP1,PEMT,WFS1,GNB4,ITGA2,ASIC1,MAPK13,KLF5,OXTR,PPARGC1A,RRAGD,MEF2C,GNG12,INPPL1,GABRB2,IPO5,ATP6V1E2,SELL,GABRG2,NKX6-1,HMGCS1,EEF2,ZNF354A,IGF1R,CA2,BCHE,PRKCD,STC2,GHR,SREBF1,LRP6,ADCY6,INAVA,ERRFI1,PCK2,SYK,DUSP1,PAK1,TRPM4,RHOQ,GSTM2,PXN,NR4A1,RAPGEF2,MGST3,HOMER2,EDEM3,RYR2,MARS,SDK1,TLR6,MGMT,BAIAP2,CPEB1,HERPUD1,GPLD1,CEBPB,TRIB3,FBN1,GNAO1,XBP1,SH3BP4,RAB31,TBC1D4,TRPC3,ATP2B4,CACNA2D1,LARP1,ATP1A3 |
| 1.103e-02 | -4.51 | GAL_LEUKEMIC_STEM_CELL_UP | MSigDB lists | GAL_LEUKEMIC_STEM_CELL_UP | 126 | 21 | 17377 | 1707 |
TNIK,PPP1R3D,MID2,MYO10,MSR1,NTRK3,MFSD6,PPP1R9A,BCL11A,MTUS1,ISG20,ABLIM1,IGF1R,KAZN,ITGB3,GAN,UNC5B,SMAD6,TSPAN9,SLIT2,LPP |
| 1.105e-02 | -4.50 | Signaling by VEGF | REACTOME pathways | R-HSA-194138 | 338 | 45 | 10287 | 971 |
WASF3,BTC,FN1,RASAL2,DUSP8,DOCK1,ITPR2,PRKCA,PRKCD,ITGB3,DAB2IP,NCAM1,MET,GFRA1,RASGRP1,PRKACB,PDGFRB,NOS3,DUSP1,FGFR4,PAK1,VEGFC,IL17RD,VAV3,PXN,SH2D2A,RAPGEF2,DUSP9,RASA3,FGF17,FGFR1,BAIAP2,MAPKAPK2,IRS2,TRIB3,NRG3,NCKAP1L,PRKCB,RASGRF2,AKT3,GRIN2D,HGF,MAPK13,SPRED3,NRP1 |
| 1.107e-02 | -4.50 | Insulin resistance | KEGG pathways | hsa04931 | 107 | 19 | 7161 | 730 |
CREB3L2,PRKAA2,PPP1R3D,SLC27A2,PRKCQ,CREB5,IRS2,TRIB3,RPS6KA2,PRKCB,AKT3,PRKCD,SREBF1,TNFRSF1A,PPARGC1A,PCK2,MAPK10,TBC1D4,NOS3 |
| 1.108e-02 | -4.50 | LEE_LIVER_CANCER_MYC_DN | MSigDB lists | LEE_LIVER_CANCER_MYC_DN | 59 | 12 | 17377 | 1707 |
MAPKAPK2,SFXN1,EFEMP1,RGS16,CFH,AASS,TDO2,CFHR1,TBC1D9,SATB1,HERPUD1,TBC1D8 |
| 1.110e-02 | -4.50 | response to BMP | biological process | GO:0071772 | 113 | 19 | 17256 | 1658 |
MSX1,ID1,RUNX2,ACVR1,SMAD9,BMPR2,LRP4,GATA3,RYR2,ACVR2B,BMP6,SKI,TGFBR3,HEYL,CHRDL1,ACVR2A,BMPR1A,BMP4,SMAD6 |
| 1.110e-02 | -4.50 | cellular response to BMP stimulus | biological process | GO:0071773 | 113 | 19 | 17256 | 1658 |
MSX1,ID1,RUNX2,ACVR1,SMAD9,BMPR2,LRP4,GATA3,RYR2,ACVR2B,BMP6,SKI,TGFBR3,HEYL,CHRDL1,ACVR2A,BMPR1A,BMP4,SMAD6 |
| 1.110e-02 | -4.50 | substrate-dependent cell migration, cell extension | biological process | GO:0006930 | 10 | 4 | 17256 | 1658 |
CTTN,NRP1,SHTN1,OPHN1 |
| 1.110e-02 | -4.50 | dichotomous subdivision of an epithelial terminal unit | biological process | GO:0060600 | 10 | 4 | 17256 | 1658 |
SEMA3C,CELSR1,NRP1,SEMA3A |
| 1.111e-02 | -4.50 | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_DN | 190 | 29 | 17377 | 1707 |
SUSD3,CREB3L2,TRPM4,AVPI1,SEC24D,MYO10,GALNT6,BLVRB,MCTP2,NDRG2,ABAT,FNDC3A,DDR1,NCS1,TBC1D19,PYCR1,SMAD3,PTPRJ,SLC30A4,SEMA4F,CDC14B,MAP2K6,RAB26,ATRNL1,KLF9,GEM,GATM,ZFP36L2,RBMS2 |
| 1.111e-02 | -4.50 | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_DN | MSigDB lists | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_DN | 190 | 29 | 17377 | 1707 |
NDUFA4L2,TBKBP1,SH3BP2,RUNX2,FOXN3,VIM,OVOL2,GPSM2,DDR1,SNX9,HOPX,DHX32,TXNDC5,SLC39A14,SLC30A4,PIK3AP1,CDC14B,ITGA2,MATN2,HK2,HPGD,TRPC1,GEM,FBXO27,ERRFI1,SLIT2,NEB,SYK,ULBP1 |
| 1.111e-02 | -4.50 | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN | 190 | 29 | 17377 | 1707 |
PAK1,ITGB7,SH3BP2,GAPDH,EVL,TUBA1A,LGALS3,PSTPIP2,NDRG2,KCTD12,COTL1,ATP1B1,DOCK5,CEBPB,RTN1,ENTPD1,FGR,NACC2,PRCP,RGS10,BCL6,RAB31,HK2,SGK1,MARCKS,COL9A2,CEBPD,ATP2B1,FZD1 |
| 1.111e-02 | -4.50 | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_UP | 190 | 29 | 17377 | 1707 |
EPHA3,EIF4E3,PNP,IL15,SELL,NPC2,LACC1,CD40,HERC6,LCP2,INPP1,TLR6,WARS,ISG20,PTPRC,CXCL10,TLR3,SETDB2,TRIM34,PIK3AP1,GNB4,P4HA1,VWA5A,CMPK2,TLR4,STXBP1,SNX10,SLFN5,PARP9 |
| 1.111e-02 | -4.50 | GSE30083_SP2_VS_SP3_THYMOCYTE_DN | MSigDB lists | GSE30083_SP2_VS_SP3_THYMOCYTE_DN | 190 | 29 | 17377 | 1707 |
GDAP1,SIDT1,RNF144A,PSTPIP2,SELL,C1R,RASD1,NTRK3,GABRR2,MGAT5B,IL18R1,CPEB1,COL27A1,C9orf116,CCDC120,RND2,TRIM9,MCOLN2,IQCH,EEPD1,SGK1,UACA,SERPINI1,GULP1,NRP1,RRAS2,SMPDL3A,ZNF385A,SLC43A1 |
| 1.111e-02 | -4.50 | GSE17721_CTRL_VS_LPS_2H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_2H_BMDC_DN | 190 | 29 | 17377 | 1707 |
FER,RAB3B,SYNPO2,MXI1,ACSL1,UGT8,BMPR2,ARID5B,CALCRL,ATF3,CD40,PALLD,INPP1,CRYBG3,GNAI1,TUBB4A,CCDC120,TMCO3,ENPP1,GYPC,CSF1,ITGB3,TSC22D1,COL19A1,PIP5KL1,RRAS2,PTPRE,TSPAN9,SEMA6C |
| 1.111e-02 | -4.50 | GSE30083_SP1_VS_SP2_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP2_THYMOCYTE_DN | 190 | 29 | 17377 | 1707 |
RGS16,ITGB7,UGT8,ADM2,ANK2,ELOVL7,FGF12,CYP4V2,LITAF,SDC3,RASA3,NRN1,ADAMTS6,HERC6,MLC1,PCDH7,SEMA4F,TRIM34,AADAT,TERT,MAP2,LHX6,PCK2,CMPK2,SLFN5,PRR16,TSPAN9,DNAH5,TC2N |
| 1.112e-02 | -4.50 | GO_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION | MSigDB lists | GO_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION | 103 | 18 | 17377 | 1707 |
GSTM2,UBASH3B,PTPN6,ANK2,JPH1,RYR2,RASA3,GSTO1,ITPR2,ASPH,SNCA,PTPRC,CXCL10,BBC3,TRPC1,PDE4D,ATG5,DDIT3 |
| 1.112e-02 | -4.50 | GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | MSigDB lists | GO_DEVELOPMENTAL_GROWTH_INVOLVED_IN_MORPHOGENESIS | 103 | 18 | 17377 | 1707 |
EPB41L5,BDNF,KDM5B,YAP1,WNT11,MAP1B,CSF1,FLRT3,PTK7,LRP6,HOXD13,BMP4,NRP1,SEMA3A,MAGI2,SPRY2,SLIT2,COBL |
| 1.115e-02 | -4.50 | regulation of cardiac muscle cell action potential | biological process | GO:0098901 | 33 | 8 | 17256 | 1658 |
TRPM4,RYR2,PKP2,FGF13,DSP,ANK2,DSG2,NOS1AP |
| 1.116e-02 | -4.50 | GO_SEGMENTATION | MSigDB lists | GO_SEGMENTATION | 88 | 16 | 17377 | 1707 |
SMAD3,EPB41L5,RGS20,PLXNA2,LRP6,MAFB,SEMA3C,BMPR1A,BMP4,NRP1,SEMA3A,MLLT3,COBL,PPP2R3A,PCSK6,DKK1 |
| 1.117e-02 | -4.49 | GO_COENZYME_METABOLIC_PROCESS | MSigDB lists | GO_COENZYME_METABOLIC_PROCESS | 248 | 36 | 17377 | 1707 |
NMNAT3,MOCOS,MVK,ACSL1,ENO2,AASS,ELOVL7,SCD,NUDT12,QPRT,AADAT,KMO,ALDOC,ALDH1L1,FAR2,ENO1,HMGCR,PFKFB4,VNN2,GAPDH,PNP,PFKFB2,MVD,ALDH1L2,PANK1,ELOVL3,OGDHL,FASN,TPK1,TDO2,PEMT,ALDOA,HK2,HK1,PANK3,OCLN |
| 1.118e-02 | -4.49 | channel activity | molecular function | GO:0015267 | 467 | 61 | 17224 | 1680 |
KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,SLC9C1,LRRC8B,KCNH5,CACNA1E,JPH1,GRID1,RYR2,CHRNA6,TTYH2,RASA3,KCND3,STEAP1,GJC1,KCNK15,GRIK4,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B |
| 1.118e-02 | -4.49 | cyclic nucleotide binding | molecular function | GO:0030551 | 39 | 9 | 17224 | 1680 |
PRKG2,PRKAR2B,PDE4D,POPDC3,BVES,PDE10A,RAPGEF2,RAPGEF4,PRKG1 |
| 1.121e-02 | -4.49 | nuclear outer membrane-endoplasmic reticulum membrane network | cellular component | GO:0042175 | 1066 | 123 | 18223 | 1724 |
CREB3L2,PLA2G4A,ACSL1,ELOVL4,LPCAT2,DNAJC3,XYLT1,ITPR2,LPIN3,SEZ6L2,CANX,ABHD4,CYP26A1,NOS1AP,CDS1,RTN1,CYP51A1,ERG28,TLR3,PDZD8,SEC16B,ERO1B,SLC10A7,ZDHHC6,REEP1,TMED9,PROS1,RASGRP1,ALG10B,CYP1B1,ATL1,ANTXR2,EVA1A,TMEM67,ERGIC1,EBPL,LRRC8B,TGFA,WLS,CYB5R2,C3orf52,JPH1,LRMP,TRAM1L1,HACD1,NFE2L1,RNF125,TRIQK,ASPH,ATP10D,SNCA,GJC1,RANBP2,INSIG1,RASGRF2,PEMT,WFS1,ERN1,ALG11,CYP2U1,MBOAT2,NR3C2,RETREG1,TYRO3,ALOX5AP,CLGN,SEC24D,CYP2J2,ELOVL7,DHCR24,CYP4V2,UBAC2,CLSTN2,SCD,SPINK5,PGAP1,MYORG,RNF180,GALNT1,BNIP1,SOAT2,MSMO1,FLRT3,SREBF1,SGK1,LMAN2,CERS4,NCEH1,MOXD1,TESPA1,CKAP4,HMGCR,FADS1,B3GLCT,SLC37A1,SLC27A2,RNF170,MGST3,AGPAT4,ELOVL3,GPSM1,RYR2,SHISA2,ARHGAP32,ILDR2,LRAT,HERPUD1,GPR37,EDA,PLOD2,FMO4,MFSD2A,XBP1,OSBPL5,SRD5A3,SQLE,MYRF,PLD1,CERS1,DHCR7,PTGES,OSBPL6,ABCG1 |
| 1.122e-02 | -4.49 | GSE24210_TCONV_VS_TREG_UP | MSigDB lists | GSE24210_TCONV_VS_TREG_UP | 182 | 28 | 17377 | 1707 |
SUSD3,VEGFC,ITGB7,LRFN5,DYRK3,SCAMP1,ITPRIP,ELOVL7,TMEM126A,ELMOD1,CR2,PRICKLE1,PLS1,SCD,SLC46A3,NEDD4,NCS1,CA13,HOPX,GSN,CFHR1,XBP1,DAB2IP,HK1,RCAN3,PTPRE,GATM,FOXA1 |
| 1.122e-02 | -4.49 | GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_UP | MSigDB lists | GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_UP | 182 | 28 | 17377 | 1707 |
PRKAA2,PTCH2,INTU,UNC5C,C2orf88,CARD6,ACVR1,TRIM2,DEPTOR,CLSTN2,OR51B4,ZFPM2,EPHB1,SATB1,CHD5,TUBB4A,SLC35F1,PCDHB7,ITGBL1,ISM1,FMO4,ATP7B,DIRAS1,BMPR1A,NIPAL2,DENND5B,TBC1D8,PGBD5 |
| 1.122e-02 | -4.49 | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | 182 | 28 | 17377 | 1707 |
MPZL3,ANO10,VAV3,ITPRIP,MYO10,WLS,MVD,FBXO4,ST6GAL1,FOXN3,LDLR,NFIA,GATA3,ASS1,RASA3,FAM117B,CD40,KBTBD11,ATP10D,AADAT,INSIG1,KIAA0355,ZBTB20,HS3ST3B1,MLLT3,KIF1B,SYK,MID1 |
| 1.122e-02 | -4.49 | GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP | 182 | 28 | 17377 | 1707 |
ARAP2,DYRK3,ACVR1,LRRC8B,MPP1,VLDLR,MCTP2,INPP1,DOK5,PHLDA2,PPP2R3A,BAIAP2,DCBLD2,MSC,AK1,KCTD15,KMO,MYC,RUNDC3B,TSC22D1,MAP7,PIK3C2B,MARCKS,SLCO4C1,SHOX2,MMP16,RBMS2,ATP2B1 |
| 1.122e-02 | -4.49 | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 182 | 28 | 17377 | 1707 |
MID2,MOCOS,MSX1,DYRK3,SLK,ITGA6,C3orf52,SETBP1,AK4,SLC25A28,ATF3,HERC6,ZDHHC14,HOXA1,PCDH7,BATF3,WARS,SKI,CXCL10,ENPP1,SLC30A4,PMAIP1,GBP1,CSF1,RGS10,HK2,SPRY4,SP140L |
| 1.122e-02 | -4.49 | GSE3982_BCELL_VS_NKCELL_UP | MSigDB lists | GSE3982_BCELL_VS_NKCELL_UP | 182 | 28 | 17377 | 1707 |
COL9A3,DNAJC3,C3orf52,BIK,SAV1,ZDHHC14,SEL1L3,SERGEF,BCL11A,ISG20,PPM1E,BACE2,EHD3,KIAA0319,HK2,OPN3,BCL6,GTF2F2,SQLE,MARCH3,MARCKS,TSHR,GATM,B4GALT7,SCN3A,LARP1,GAB2,GLDC |
| 1.122e-02 | -4.49 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | 182 | 28 | 17377 | 1707 |
ITGB7,GARS,GAPDH,ENO2,COL4A3,BLVRB,SYBU,CRIP2,VIM,CCNG1,COTL1,FKBP11,HOMER3,ZBTB38,EHD3,XBP1,RAB31,RGS10,SCRN1,TOX,ZBTB20,MARCKS,SP140,TBC1D9,TNFRSF17,TESC,RASGRP1,ATP2B4 |
| 1.122e-02 | -4.49 | GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_DN | MSigDB lists | GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_DN | 182 | 28 | 17377 | 1707 |
MYO10,DOCK1,ATOX1,AK4,SLC25A28,C1R,SPATS2L,BATF,HERC6,CLN5,WARS,BATF3,CXCL10,UNC13B,SCN1B,P4HA2,SLC2A6,PAM,MAOA,STEAP3,BNIP3,PLD1,SERPINH1,PLTP,SNX10,HSPA2,ATP2B4,RBMS2 |
| 1.122e-02 | -4.49 | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | 182 | 28 | 17377 | 1707 |
SUSD3,TNIK,TRIM16,GALNT12,ARID5B,IPO5,MORC4,GATA3,PHACTR2,PRKCQ,STAT5B,BATF,TNKS1BP1,SERGEF,ISG20,ATXN7L1,DEXI,BAG3,TECPR1,RASGRF2,FAM107B,MAPK13,IPCEF1,MAST4,TBC1D4,MLLT3,PHC1,DOCK9 |
| 1.124e-02 | -4.49 | calcium ion transmembrane transport | biological process | GO:0070588 | 186 | 28 | 17256 | 1658 |
TRPM4,GPM6A,CACNG3,CACNA1E,MCOLN3,RYR2,RASA3,ITPR2,GAS6,CACNB4,NCS1,MCU,PTPRC,MCOLN2,CACNB2,BHLHA15,ASIC1,TRPC1,GRIN2D,TMEM37,FAM155B,TRPC3,FAM155A,DDIT3,CACNA2D1,ATP2B1,ATP2B4,DENND5B |
| 1.128e-02 | -4.49 | fourth_ventricle | COSMIC cancer mutations | fourth_ventricle | 39 | 9 | 17385 | 1698 |
ACVR1,TERT,NACC2,RNF130,KIAA1217,MET,KIAA1549,FGFR1,GNAI1 |
| 1.130e-02 | -4.48 | CACTGTG,MIR-128A,MIR-128B | MSigDB lists | CACTGTG,MIR-128A,MIR-128B | 316 | 44 | 17377 | 1707 |
MXI1,ELOVL4,ARHGEF11,RNF144A,CLSTN2,ENAH,NTRK3,CANX,PGAP1,STK24,NEO1,ZNF827,PPM1E,KCNAB1,MGAT1,CDC14B,MPPED2,ACVR2A,STEAP3,FAM84B,FAM155B,TMEM132E,SEPT3,ZNF385A,IGSF3,FADS1,FOXN3,AGPAT4,MGAT4B,HIP1,ARRDC4,BCL11A,RERE,ARHGAP21,RND3,SH3RF1,PLK2,CSF1,C1orf21,MPP2,DIRAS1,SH3BGRL2,APBA2,MME |
| 1.131e-02 | -4.48 | GSE22886_NAIVE_CD4_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_DC_UP | 174 | 27 | 17377 | 1707 |
BCL11B,VNN2,IL32,APBB1,GATA3,CCNG1,CD7,PLEKHB1,FKBP11,ISG20,LGI2,KLF12,EEF2,GYPC,CDC14B,PCBP4,ALDOC,WDR19,INPP4B,KLF9,PDE4D,IPCEF1,TBC1D4,PKIA,SNPH,DUSP1,DOCK9 |
| 1.131e-02 | -4.48 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_DN | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_DN | 174 | 27 | 17377 | 1707 |
TBKBP1,ID1,RUNX2,FLVCR2,FAM124A,PTPN13,BIK,KIF5C,BATF,SEL1L3,NEO1,MSC,KCTD15,SLC22A17,GPRC5B,NACC2,ZFYVE28,GBP1,INPP4B,MAOA,ACVR2A,ACTA2,KIF21A,RNF157,STOM,GLDC,DOCK9 |
| 1.131e-02 | -4.48 | GSE36095_WT_VS_HDAC9_KO_TREG_UP | MSigDB lists | GSE36095_WT_VS_HDAC9_KO_TREG_UP | 174 | 27 | 17377 | 1707 |
TUBA1A,PDE1B,SLC27A2,TGFA,IPO5,UBAC2,SPATA13,CR2,ADAMTS6,GSTO1,WDFY4,SNX9,PPP2R3A,AKAP7,FAM114A2,PLXDC2,ALDOC,PPFIBP1,PLK2,XBP1,SQLE,ADCY6,PROS1,RAPGEF5,FAM78B,MEF2C,SLC43A1 |
| 1.131e-02 | -4.48 | JNK_DN.V1_DN | MSigDB lists | JNK_DN.V1_DN | 174 | 27 | 17377 | 1707 |
VEGFC,TNIK,FER,TBKBP1,QSOX1,RGS16,SV2B,INPPL1,DYRK3,DUSP8,SMAD9,RAB6B,SMARCD3,NDRG2,ZIC2,EPHB1,PLCB1,NOVA1,MBNL2,FAM110B,STEAP1,MAP1B,FAM131B,NELL2,TYMP,KPNA3,FABP6 |
| 1.131e-02 | -4.48 | - | gene3d domains | 3.10.20.710 | 2 | 2 | 8148 | 867 |
SATB2,SATB1 |
| 1.131e-02 | -4.48 | - | gene3d domains | 1.10.260.70 | 2 | 2 | 8148 | 867 |
SATB2,SATB1 |
| 1.131e-02 | -4.48 | nerve development | biological process | GO:0021675 | 75 | 14 | 17256 | 1658 |
BDNF,UNC13B,GABRB2,COL25A1,CTSV,TMEM126A,TFAP2A,AHNAK2,MAFB,SLC1A3,NRP1,EPHB1,SEMA3A,HOXA1 |
| 1.131e-02 | -4.48 | regulation of smoothened signaling pathway | biological process | GO:0008589 | 75 | 14 | 17256 | 1658 |
PTCH2,INTU,RUNX2,CHSY1,DISP1,DYNC2H1,SHOX2,GAS1,GPR161,BTRC,FOXA1,PRKACB,ZIC1,GLI1 |
| 1.131e-02 | -4.48 | cardiac muscle contraction | biological process | GO:0060048 | 75 | 14 | 17256 | 1658 |
SCN5A,KCNN2,SCN1B,CACNB2,ANK2,MAP2K6,FGF12,RYR2,PKP2,KCND3,ATP1B1,TPM1,CACNA2D1,GJC1 |
| 1.132e-02 | -4.48 | GSE14415_INDUCED_VS_NATURAL_TREG_UP | MSigDB lists | GSE14415_INDUCED_VS_NATURAL_TREG_UP | 142 | 23 | 17377 | 1707 |
LATS2,CARD6,CD55,KCNIP3,IL15,CLGN,WLS,FAM84A,CALCRL,KIF5C,CR2,CCNG1,CD7,PFN2,FBXO32,EOMES,EIF1,PGM2L1,SERPINI1,GEM,TNFSF4,TBC1D4,DUSP1 |
| 1.132e-02 | -4.48 | GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_UP | 142 | 23 | 17377 | 1707 |
CARD6,EVL,KLHL3,GPR65,CYTH3,ELOVL7,RAPGEF4,TNFAIP8L2,TTYH2,RASA3,SELL,NPC2,PGAP1,RPL13A,TMEM154,GPRC5B,AKT3,TNFRSF1A,RUNDC3B,BNIP3,IPCEF1,NRP1,SLFN5 |
| 1.132e-02 | -4.48 | regulation of lipid metabolic process | biological process | GO:0019216 | 367 | 49 | 17256 | 1658 |
BCL11B,PRKAA2,SORBS1,MVK,ACSL1,LDLR,STAT5B,SCD,PIBF1,ABHD6,BMP6,TIAM2,CYP51A1,PLPP1,IDI1,HMGCS1,GRHL1,PRKCD,STARD4,SREBF1,DAB2IP,GFI1,SLC45A3,PDGFRB,SNAI2,HMGCR,FADS1,FGFR4,VAV3,PDK1,MVD,FASN,FHL2,SMARCD3,AGAP2,NPC2,RARRES2,RACK1,GPLD1,SNCA,IRS2,TRIB3,FGR,INSIG1,TNFRSF1A,SQLE,PPARGC1A,DHCR7,ABCG1 |
| 1.135e-02 | -4.48 | - | gene3d domains | 3.30.505.10 | 110 | 20 | 8148 | 867 |
RIN2,FER,VAV3,SH3BP2,INPPL1,SH2D2A,GRB14,PTPN6,STAT4,TNS1,STAT5B,LCP2,FRK,CHN1,CHN2,FGR,SHF,GRB10,SYK,FES |
| 1.137e-02 | -4.48 | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP | 166 | 26 | 17377 | 1707 |
SUSD3,SERINC5,MXI1,ITPRIP,KLHL3,CKAP2,GPR65,UBASH3B,ITGA6,RNF125,MBNL2,HEG1,GABARAPL1,NAP1L5,ZNF711,IRS2,OTUD1,PELI2,TSC22D1,ZBTB20,PDE4D,FHIT,SUSD4,PERP,DUSP1,PCSK5 |
| 1.137e-02 | -4.48 | GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN | MSigDB lists | GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN | 166 | 26 | 17377 | 1707 |
DMXL2,ACSL1,SCAMP1,KLHL13,LPCAT2,HEBP1,BLVRB,GDPD1,OPHN1,TTYH2,MAFB,LCP2,NOVA1,PGAP1,ZFYVE9,MTUS1,IRS2,GBGT1,FCHO2,PRKCB,HPGD,LRP6,PROS1,NCEH1,RASGRP1,DUSP1 |
| 1.137e-02 | -4.48 | GO_SIGNAL_RELEASE | MSigDB lists | GO_SIGNAL_RELEASE | 166 | 26 | 17377 | 1707 |
DOC2A,SLC6A9,FZD4,SYT12,WLS,RAPGEF4,GATA3,ACVR2B,SNAP25,APBA1,NRXN1,SYT14,PCLO,ILDR2,RAB11FIP5,TRIM9,UNC13B,PPFIA2,PTPRN2,LIN7A,CADPS2,SEPT5,STXBP1,TC2N,RIMS2,SNPH |
| 1.137e-02 | -4.48 | GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN | 166 | 26 | 17377 | 1707 |
FADS1,QSOX1,MICAL2,COL9A3,ACSL1,LGALS3,FLVCR2,ARHGEF11,BLVRB,BNIP3L,IL13RA1,CHSY1,SNCA,HOMER3,CTIF,CYP51A1,ENTPD1,GSN,MAP1A,PELI2,ALDOA,EIF1,BCL6,STEAP3,CKAP4,CYP1B1 |
| 1.137e-02 | -4.48 | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | 166 | 26 | 17377 | 1707 |
EML5,BTC,MARK1,PRSS12,GRB14,SPATA6,EPS8,TNFSF13B,LITAF,FAM102B,FEZ1,COL4A5,CTBP2,ATF3,NPC2,TNFRSF19,ZNF618,CTNNA2,TRPS1,CXCL10,PIK3AP1,PLOD2,GBP1,FMNL2,FZD1,STOM |
| 1.138e-02 | -4.48 | GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 150 | 24 | 17377 | 1707 |
ARAP2,RNF145,ST6GAL1,CYTH3,MCTP2,GTF2IRD1,RYR2,PRKAR2B,KIF21B,LCP2,PHLDA2,SPIRE1,ISG20,ABLIM1,GPR155,BCL6,CDH17,PIK3C2B,SLC16A9,CERS4,NRP1,MAST4,FKBP14,RASGRP1 |
| 1.146e-02 | -4.47 | GIPC1 (GIPC PDZ domain containing family member 1) | protein interactions | 10755 | 51 | 11 | 17029 | 1718 |
TGFBR3,IGF1R,ITGA6,SH3BP4,ADRB1,HECW2,MARS,MYO6,NRP1,KIF1B,DDIT3 |
| 1.147e-02 | -4.47 | GO_CELL_BODY | MSigDB lists | GO_CELL_BODY | 482 | 63 | 17377 | 1707 |
MYO1D,PDE1B,ENO2,BMPR2,GRIK2,AKAP5,KIF5A,LRP4,APBB1,ASS1,SLC1A3,P2RY1,NRXN1,CANX,DNER,GDPD5,RAC3,PPP1R9A,TUBB4A,NELL2,KCNJ4,KCNN2,KCNAB1,CHRNA5,PDE10A,ACTA2,LRP6,DAB2IP,CPE,ZNF385A,SCN3A,ATP2B1,KCNB2,TRPM4,DPYSL5,DISC1,GPM6A,MYO10,PTPN13,RAPGEF2,SHANK2,LRRK2,HOMER2,PRKAR2B,EFHC1,GSTO1,AMIGO1,KCND3,TTLL7,CPEB1,BAIAP2,GABARAPL1,CAMK2N1,RPL28,GNAO1,PAM,BMPR1A,NRP1,PPARGC1A,COBL,LZTS1,CTNND2,SNPH |
| 1.151e-02 | -4.46 | GO_CELLULAR_RESPONSE_TO_STARVATION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_STARVATION | 111 | 19 | 17377 | 1707 |
PRKAA2,FADS1,ATF4,BMPR2,VLDLR,LRRK2,NUAK2,ATF3,GAS6,GABARAPL1,ASNS,PMAIP1,BHLHA15,XBP1,SREBF1,CADPS2,ATG5,RNF152,RRAGD |
| 1.155e-02 | -4.46 | WHEP-TRS | smart domains | SM00991 | 5 | 3 | 9493 | 1056 |
MARS,GARS,WARS |
| 1.156e-02 | -4.46 | MITSIADES_RESPONSE_TO_APLIDIN_UP | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_UP | 403 | 54 | 17377 | 1707 |
AVPI1,ALOX5AP,SIDT1,AASS,LDLR,CBS,ZNF215,FAM13A,DENND3,MTUS1,RPS6KA2,IDI1,KMO,TACC2,MCF2L,EIF1,MARCKS,SLCO4C1,ETV1,SP140L,CTH,NKX2-1,DUSP1,BDNF,SLC3A2,PNRC1,SH2D2A,RAPGEF2,ARID5B,C3orf52,NFE2L1,PDE8A,TGDS,INTS6,HERPUD1,GABARAPL1,ISG20,CEBPB,SMAD3,BEX4,IRS2,GALNT3,ID3,PDLIM3,KIAA0355,TUFT1,BBC3,GEM,PPARGC1A,TESC,AMPD1,DDIT3,STOM,ABCG1 |
| 1.156e-02 | -4.46 | Developmental Biology | REACTOME pathways | R-HSA-1266738 | 1075 | 123 | 10287 | 971 |
EPHA3,BTC,DNM3,CACNG3,RASAL2,DUSP8,ST14,DOCK1,PLXNA2,PKP2,ENAH,CEBPA,PRKCA,CACNB4,SEMA6A,CTNNA2,LGI2,RPS6KA2,KAZN,ITGB3,ACVR2A,TRPC1,DAB2IP,EPHB6,SCN2A,MET,SLIT2,RASGRP1,PERP,PRKACB,SCN3A,PDGFRB,GAB2,COL6A2,EVL,COL4A3,ACVR1C,NR6A1,DCC,CAP2,ANK2,MEF2B,PRKCQ,ACVR2B,FGF17,DSP,FGFR1,SMAD3,IRS2,NRG3,RASGRF2,LAMB1,ITGA2,KLF5,GRB10,HGF,UNC5B,NRP1,PPARGC1A,CNTN1,MEF2C,EFNB2,COL9A3,SCN5A,ROBO2,FN1,ARHGEF11,PAK5,SCN8A,COL4A5,EPHB1,PFN2,SPINK5,DOK5,NEO1,NKX6-1,ABLIM1,SCN1B,CACNB2,DSG2,SREBF1,SRGAP1,MED7,NCAM1,COL9A2,GFRA1,CEBPD,FES,PCSK6,DUSP1,FGFR4,DPYSL5,PDLIM7,PAK1,IL17RD,VAV3,UNC5C,ARHGEF28,KCNQ3,MYO10,HNF4G,RAPGEF2,COL4A4,EFNA3,DUSP9,SMARCD3,RASA3,MAFB,AGAP2,HOXA1,CEBPB,PTPRC,EBF1,SH3GL2,AKT3,MAP2K6,PCGF2,GRIN2D,SPRED3,CDH2,TRPC3,SEMA3A,SHTN1 |
| 1.161e-02 | -4.46 | SSH1 (slingshot protein phosphatase 1) | protein interactions | 54434 | 38 | 9 | 17029 | 1718 |
GSN,MYO1D,IGF1R,KIAA1671,DSTN,SVIL,ACTA2,TMOD2,SCIN |
| 1.165e-02 | -4.45 | LIM | smart domains | SM00132 | 72 | 15 | 9493 | 1056 |
PDLIM7,ABLIM1,MICAL2,PXN,PDLIM3,TES,CRIP2,LHX6,LMCD1,FHL2,PRICKLE1,PRICKLE2,LIMCH1,CSRP2,LPP |
| 1.165e-02 | -4.45 | cholesterol biosynthesis II (via 24,25-dihydrolanosterol) | BIOCYC pathways | HUMAN_PWY66-3 | 13 | 5 | 902 | 105 |
SQLE,CYP51A1,DHCR7,MSMO1,DHCR24 |
| 1.165e-02 | -4.45 | cholesterol biosynthesis I | BIOCYC pathways | HUMAN_PWY66-341 | 13 | 5 | 902 | 105 |
SQLE,CYP51A1,DHCR7,MSMO1,DHCR24 |
| 1.165e-02 | -4.45 | cholesterol biosynthesis III (via desmosterol) | BIOCYC pathways | HUMAN_PWY66-4 | 13 | 5 | 902 | 105 |
SQLE,CYP51A1,DHCR7,MSMO1,DHCR24 |
| 1.166e-02 | -4.45 | GO_PRESYNAPSE | MSigDB lists | GO_PRESYNAPSE | 274 | 39 | 17377 | 1707 |
DOC2A,DMXL2,SV2B,SLC6A9,SCAMP1,PRSS12,GRIK2,SYT12,APBB1,OPHN1,KCTD12,APBA1,NRXN1,PFN2,PCLO,UNC13B,PPFIA2,LIN7A,CADPS2,SYNGR3,STXBP1,RIMS2,SLC40A1,DISC1,RAB3B,LRRK2,RABAC1,SNAP25,SNCA,TRIM9,GRIK4,ICA1,PTPRN2,SEPT5,APBA2,CTTNBP2,STON2,MME,SNPH |
| 1.167e-02 | -4.45 | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | 232 | 34 | 17377 | 1707 |
MYCBP2,NBL1,ALOX5AP,PKN1,DDR1,CD53,EFEMP1,CHN1,ACTA2,CYP1B1,PAK1,QSOX1,RIN2,COL6A2,PNP,CRIP2,LITAF,NPC2,MAP1B,PTPRC,CD37,ID3,GYPC,FBN1,AKT3,ALDOA,LAMB1,SLC7A5,RAB31,PAM,KLF5,HK1,GEM,SLC1A5 |
| 1.167e-02 | -4.45 | V$TAL1BETAE47_01 | MSigDB lists | V$TAL1BETAE47_01 | 232 | 34 | 17377 | 1707 |
PHACTR3,SCN5A,KLF8,ARHGAP22,RASL11B,CADM2,BEX2,ARHGAP44,FOXP2,LRRN1,SCN1B,SMTN,TRIM3,MAP7,HRK,TSPAN13,GFI1,GFRA1,NEB,NDUFA4L2,MARK1,WWC1,ZFPM2,FNDC3A,MBNL2,PLCB1,TSKU,SMAD3,HTR7,ITGBL1,INHBE,NXPH4,DDIT3,MEF2C |
| 1.167e-02 | -4.45 | passive transmembrane transporter activity | molecular function | GO:0022803 | 468 | 61 | 17224 | 1680 |
KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,SLC9C1,LRRC8B,KCNH5,CACNA1E,JPH1,GRID1,RYR2,CHRNA6,TTYH2,RASA3,KCND3,STEAP1,GJC1,KCNK15,GRIK4,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B |
| 1.168e-02 | -4.45 | FYB1 (FYN binding protein 1) | protein interactions | 2533 | 20 | 6 | 17029 | 1718 |
ENAH,PRKCQ,EVL,SKAP2,LCP2,SKAP1 |
| 1.168e-02 | -4.45 | DUSP18 (dual specificity phosphatase 18) | protein interactions | 150290 | 20 | 6 | 17029 | 1718 |
EPHA3,ROR1,EPHB6,IGF1R,PTK7,PTPN6 |
| 1.168e-02 | -4.45 | GRM5 (glutamate metabotropic receptor 5) | protein interactions | 2915 | 20 | 6 | 17029 | 1718 |
EFNB2,PRKCQ,PRKCA,PRKCB,PRKCD,HOMER3 |
| 1.168e-02 | -4.45 | RAET1E (retinoic acid early transcript 1E) | protein interactions | 135250 | 20 | 6 | 17029 | 1718 |
ALG11,NRN1,PODXL2,RAB3B,NCR3LG1,FGFR1 |
| 1.168e-02 | -4.45 | EPHB1 (EPH receptor B1) | protein interactions | 2047 | 20 | 6 | 17029 | 1718 |
EFNB2,GRB10,EPHB6,PXN,EPHB1,PDGFRB |
| 1.169e-02 | -4.45 | BMP signaling pathway | biological process | GO:0030509 | 98 | 17 | 17256 | 1658 |
MSX1,ID1,RUNX2,ACVR1,SMAD9,BMPR2,LRP4,RYR2,ACVR2B,BMP6,SKI,TGFBR3,CHRDL1,ACVR2A,BMP4,BMPR1A,SMAD6 |
| 1.169e-02 | -4.45 | chr4p15 | MSigDB lists | chr4p15 | 39 | 9 | 17377 | 1707 |
LGI2,ARAP2,PPARGC1A,SEL1L3,TBC1D1,SLIT2,UGDH,PCDH7,TBC1D19 |
| 1.169e-02 | -4.45 | V$HMX1_01 | MSigDB lists | V$HMX1_01 | 39 | 9 | 17377 | 1707 |
SMAD3,SLC25A28,LRRK1,ATOH1,ID1,CACNB2,CBLN1,KCNB2,FGF12 |
| 1.169e-02 | -4.45 | GO_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL | MSigDB lists | GO_MEMBRANE_DEPOLARIZATION_DURING_ACTION_POTENTIAL | 39 | 9 | 17377 | 1707 |
SCN5A,SCN1B,CACNA1E,SCN8A,ANK2,CACNB2,SCN2A,SCN3A,CACNA2D1 |
| 1.169e-02 | -4.45 | KEGG_TRYPTOPHAN_METABOLISM | MSigDB lists | KEGG_TRYPTOPHAN_METABOLISM | 39 | 9 | 17377 | 1707 |
ALDH2,EHHADH,AADAT,TDO2,KMO,OGDHL,MAOA,CYP1B1,WARS |
| 1.169e-02 | -4.45 | GO_CELL_SUBSTRATE_JUNCTION_ASSEMBLY | MSigDB lists | GO_CELL_SUBSTRATE_JUNCTION_ASSEMBLY | 39 | 9 | 17377 | 1707 |
SORBS1,FN1,RHOD,ITGA6,ITGB3,ITGA2,FERMT2,TNS1,CTTN |
| 1.170e-02 | -4.45 | carbohydrate:proton symporter activity | molecular function | GO:0005351 | 10 | 4 | 17224 | 1680 |
SLC2A12,SLC2A13,SLC45A3,SLC2A6 |
| 1.170e-02 | -4.45 | phosphatidylinositol 3-kinase regulatory subunit binding | molecular function | GO:0036312 | 10 | 4 | 17224 | 1680 |
DAB2IP,FBXL2,PIK3AP1,PTPN13 |
| 1.177e-02 | -4.44 | Na_trans_assoc | pfam domains | PF06512 | 10 | 4 | 17054 | 1666 |
SCN5A,SCN2A,SCN8A,SCN3A |
| 1.177e-02 | -4.44 | GRADE_COLON_AND_RECTAL_CANCER_DN | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_DN | 96 | 17 | 17377 | 1707 |
C2orf88,SESN2,UGDH,CBS,COL4A5,JAM3,RERE,TRPS1,SNCA,TGFBR3,NAV1,SLC16A9,PLD1,TLN2,UNC5B,GFI1,PRKACB |
| 1.177e-02 | -4.44 | GO_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_GLUCOSE_METABOLIC_PROCESS | 96 | 17 | 17377 | 1707 |
PPP1R3D,SORBS1,SESN2,PDK1,C1QTNF3,PFKFB2,PHLDA2,LEPR,GPLD1,IRS2,ENPP1,RANBP2,PMAIP1,GRB10,PPARGC1A,SLC45A3,IGFBP3 |
| 1.177e-02 | -4.44 | BROWNE_HCMV_INFECTION_20HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_DN | 96 | 17 | 17377 | 1707 |
FARP1,TRIM2,TGFBR3,FRY,RND3,RHOBTB1,CAP2,PTPN13,AKT3,ACO1,SVIL,GSTO1,FBXL2,RRAS2,ATP2B1,LPP,TBC1D8 |
| 1.177e-02 | -4.44 | GO_EXTRINSIC_COMPONENT_OF_CYTOPLASMIC_SIDE_OF_PLASMA_MEMBRANE | MSigDB lists | GO_EXTRINSIC_COMPONENT_OF_CYTOPLASMIC_SIDE_OF_PLASMA_MEMBRANE | 96 | 17 | 17377 | 1707 |
TNK2,FER,GNG12,FARP1,CYTH3,FERMT2,RGS7,FRK,SNX9,GNAI1,FGR,KCNAB1,MCF2L,GNAO1,ERRFI1,SYK,FES |
| 1.178e-02 | -4.44 | hand | COSMIC cancer mutations | hand | 575 | 73 | 17385 | 1698 |
MTG1,PHACTR3,MYCBP2,ADAL,TCTN2,GALNT6,HECW2,ADD2,CADM2,ADAMTS6,KIF21B,SEZ6L2,DNER,HMCN1,ZFYVE9,COL22A1,UNC13B,TACC2,TMEM86A,MET,DNAH5,MYT1,PGBD5,ATL1,MYLK3,DCC,SLC39A8,SHANK2,ZNF565,PREX1,CR2,ATOH1,INTS6,FGFR1,MAGEA12,PDLIM3,ATP7B,CCBE1,INPP4B,ZNF704,HGF,UNC5B,FARP1,FN1,CLGN,ARHGEF11,UBASH3B,COL4A5,DOK5,FSD1,KIAA1958,KCNJ4,CNTN4,FRY,TRIM3,SEPT3,CAND2,UNC5C,SLC40A1,SLITRK2,PRICKLE1,STRADB,PEX5L,AMDHD1,MMP15,PTPRC,DPY19L2,PLEKHH2,MYADM,ZNF214,EMILIN2,LRRIQ3,THAP10 |
| 1.178e-02 | -4.44 | GO_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING | MSigDB lists | GO_CELL_COMMUNICATION_BY_ELECTRICAL_COUPLING | 15 | 5 | 17377 | 1707 |
PKP2,RYR2,DBN1,ATP1B1,ATP1A3 |
| 1.178e-02 | -4.44 | MODULE_563 | MSigDB lists | MODULE_563 | 15 | 5 | 17377 | 1707 |
MAOA,ABAT,SLC1A3,SNAP25,SNPH |
| 1.178e-02 | -4.44 | ZHANG_GATA6_TARGETS_UP | MSigDB lists | ZHANG_GATA6_TARGETS_UP | 15 | 5 | 17377 | 1707 |
POF1B,GALNT13,GSTO1,FUT9,TESC |
| 1.178e-02 | -4.44 | GO_RECEPTOR_SERINE_THREONINE_KINASE_BINDING | MSigDB lists | GO_RECEPTOR_SERINE_THREONINE_KINASE_BINDING | 15 | 5 | 17377 | 1707 |
SYNJ2BP,BMP4,MAGI2,SMAD6,BMP6 |
| 1.178e-02 | -4.44 | GO_RESPONSE_TO_FOLIC_ACID | MSigDB lists | GO_RESPONSE_TO_FOLIC_ACID | 15 | 5 | 17377 | 1707 |
GSN,ZNF354A,EEF2,BCHE,MGMT |
| 1.178e-02 | -4.44 | chr2q22 | MSigDB lists | chr2q22 | 15 | 5 | 17377 | 1707 |
ACVR2A,SCN2A,CACNB4,GRB14,NEB |
| 1.178e-02 | -4.44 | VETTER_TARGETS_OF_PRKCA_AND_ETS1_UP | MSigDB lists | VETTER_TARGETS_OF_PRKCA_AND_ETS1_UP | 15 | 5 | 17377 | 1707 |
TRPC1,FN1,INSIG1,SCAMP1,BCL11A |
| 1.178e-02 | -4.44 | GO_GABAERGIC_NEURON_DIFFERENTIATION | MSigDB lists | GO_GABAERGIC_NEURON_DIFFERENTIATION | 15 | 5 | 17377 | 1707 |
DLX2,GATA2,RAC3,LHX6,NKX2-1 |
| 1.178e-02 | -4.44 | KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS | MSigDB lists | KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS | 15 | 5 | 17377 | 1707 |
IDI1,MVK,HMGCS1,MVD,HMGCR |
| 1.178e-02 | -4.44 | GO_AMINO_ACID_IMPORT | MSigDB lists | GO_AMINO_ACID_IMPORT | 15 | 5 | 17377 | 1707 |
SLC7A2,SLC3A2,SLC1A3,SLC6A9,SH3BP4 |
| 1.178e-02 | -4.44 | GO_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | MSigDB lists | GO_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS | 15 | 5 | 17377 | 1707 |
EFNB2,NRP1,NR4A1,SLIT2,GPLD1 |
| 1.178e-02 | -4.44 | GO_VENOUS_BLOOD_VESSEL_DEVELOPMENT | MSigDB lists | GO_VENOUS_BLOOD_VESSEL_DEVELOPMENT | 15 | 5 | 17377 | 1707 |
SEMA3C,ACVR2B,BMPR2,CCBE1,HEG1 |
| 1.178e-02 | -4.44 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | MSigDB lists | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | 15 | 5 | 17377 | 1707 |
GPT2,ASNS,PHGDH,PSPH,PYCR1 |
| 1.181e-02 | -4.44 | TOOKER_GEMCITABINE_RESISTANCE_DN | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_DN | 119 | 20 | 17377 | 1707 |
MSX1,CD55,SLC3A2,IGFBP6,IPO5,SCD,MARS,CEBPB,SLC39A14,TRIB3,ASNS,SLC7A11,PLOD2,P4HA2,EIF4EBP1,WWTR1,SLC7A5,SH3BP4,SERPINH1,SMAD6 |
| 1.181e-02 | -4.44 | cytoplasmic side of membrane | cellular component | GO:0098562 | 198 | 29 | 18223 | 1724 |
TNK2,FER,GNG12,FARP1,RASAL2,AKAP5,CYTH3,LRRK2,LITAF,FERMT2,HIP1,RASA3,CHUK,SNAP25,RGS7,FRK,SNX9,CACNB4,GNAI1,FGR,KCNAB1,GNAO1,DAB2IP,GEM,NPTXR,ERRFI1,SYK,FES,ATP2B1 |
| 1.182e-02 | -4.44 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | 771 | 95 | 17377 | 1707 |
PLA2G4A,ACVR1,SORBS1,RASAL2,TRIM16,IL15,UGDH,ASS1,CHAC1,FAM13A,AARS,CCNJ,ZSCAN5A,BAG3,CDR2L,IKZF5,PMAIP1,ACVR2A,SERPINH1,SYNGR3,RCAN3,CTH,RWDD2A,SLC3A2,CD55,ATF4,PNRC1,C3orf52,ATF3,RNF44,FGFR1,GNAI1,GABARAPL1,GJC1,IRS2,SLC39A14,TCF7L1,GPRC5B,KLF12,P4HA2,CCNA1,ITGA2,AHNAK2,HPGD,KLF5,GRB10,TANC2,PSPH,RRAGD,HEY1,MXI1,DYRK3,ZNF395,LGALS3,SEC24D,MLF1,SLK,GTF2IRD1,TJP1,PRRG4,DDIT4,MTUS1,RGS17,IGF1R,SLC7A11,ZNF354A,PDE10A,STC2,EIF1,PRKCD,TSC22D1,KLF9,RRAS2,SPRY2,GPR161,ATP2B1,CEBPD,DUSP1,MID2,MSX1,RHOQ,KDM5B,PALLD,TGDS,MBNL2,HERPUD1,CEBPB,TRIB3,RND3,KIAA0355,XBP1,WDR19,GEM,ATP2B4,DDIT3 |
| 1.185e-02 | -4.44 | regulation of natural killer cell activation | biological process | GO:0032814 | 27 | 7 | 17256 | 1658 |
STAT5B,TOX,PRDM1,GAS6,PIBF1,IL15,RASGRP1 |
| 1.185e-02 | -4.44 | negative regulation of dendrite development | biological process | GO:2000171 | 27 | 7 | 17256 | 1658 |
PTPRS,DNM3,ID1,DCC,PLK2,RAPGEF2,KIAA0319 |
| 1.186e-02 | -4.43 | V$TTF1_Q6 | MSigDB lists | V$TTF1_Q6 | 249 | 36 | 17377 | 1707 |
UST,MXI1,GCAT,NDRG2,PRDM8,OVOL2,NOVA1,HPCAL4,FOXP2,SPEG,ABLIM1,MYC,PPFIBP1,LHX6,STC2,ZNF521,ADCY6,DAB2IP,C15orf41,NKX2-1,GLI1,GPM6A,CYTH3,MAFB,ROR1,FGF17,ZIC1,DOCK7,ICA1,PTK7,ERN1,CLMN,KLF5,SPRY4,BMP4,CNTN1 |
| 1.187e-02 | -4.43 | Na_channel_asu | interpro domains | IPR001696 | 10 | 4 | 18492 | 1811 |
SCN5A,SCN2A,SCN8A,SCN3A |
| 1.187e-02 | -4.43 | Na_trans_assoc | interpro domains | IPR010526 | 10 | 4 | 18492 | 1811 |
SCN5A,SCN2A,SCN8A,SCN3A |
| 1.189e-02 | -4.43 | human chr13q14.2 | chromosome location | human chr13q14.2 | 34 | 7 | 26185 | 1967 |
LINC00562,CAB39L,FNDC3A,KPNA3,SETDB2,EBPL,ESD |
| 1.189e-02 | -4.43 | human chr3q23 | chromosome location | human chr3q23 | 34 | 7 | 26185 | 1967 |
CLSTN2,TRPC1,NMNAT3,PLS1,ZBTB38,PCOLCE2,PXYLP1 |
| 1.191e-02 | -4.43 | GSE29618_BCELL_VS_MDC_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DN | 191 | 29 | 17377 | 1707 |
PAK1,GAPDH,PSTPIP2,NDRG2,KCTD12,VIM,GSTO1,IL13RA1,SCD,CUEDC2,COTL1,SPATS2L,ATP1B1,CANX,IL18R1,BATF3,DDIT4,RTN1,GSN,PRCP,RGS10,SH3BP4,RAB31,RNF130,IPCEF1,ENO1,CEBPD,FZD1,STOM |
| 1.191e-02 | -4.43 | GSE360_DC_VS_MAC_L_MAJOR_DN | MSigDB lists | GSE360_DC_VS_MAC_L_MAJOR_DN | 191 | 29 | 17377 | 1707 |
SCN5A,GCNT2,KLHL23,SEC24D,SLC27A2,SHANK2,PRRG1,PRDM1,NHP2,LCP2,SKAP1,DYNC1I1,TTC28,IL18R1,ARHGAP44,FAM131B,HEG1,CHRNA5,SLC16A2,RPS11,ALDOA,CHRDL1,NDUFB8,ZBTB20,MPDZ,ERCC5,PPP2R2B,DHCR7,KIF1B |
| 1.191e-02 | -4.43 | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN | MSigDB lists | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN | 191 | 29 | 17377 | 1707 |
TFCP2L1,GCA,DOCK1,DNAJC3,STXBP6,PTPN21,DHCR24,LITAF,NDRG2,KCTD12,NPC2,CANX,ZDHHC14,CLN5,GLCE,PLS3,GPR37,HMGCS1,IDI1,PMEPA1,GNB4,CACNB2,PAM,RGS10,ADCY6,LAPTM4B,VWA5A,RNF157,ABCG1 |
| 1.191e-02 | -4.43 | GSE7852_TREG_VS_TCONV_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_UP | 191 | 29 | 17377 | 1707 |
LONRF1,ERGIC1,SCAMP1,BMPR2,RHOD,WLS,UBASH3B,ARID5B,YPEL2,NRN1,GSTO1,C3orf70,ARRDC4,IKZF2,ISG20,MAPKAPK2,KIAA1958,PLAGL1,PMEPA1,ALDOC,MATN2,PTPRS,LAPTM4B,SH3BGRL2,TSPAN13,INPP5F,MED7,VWA5A,NEB |
| 1.191e-02 | -4.43 | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_DN | 191 | 29 | 17377 | 1707 |
WASF3,EIF4E3,SLC37A1,PNP,BMPR2,PRSS12,SLC27A2,ARID5B,ATF7IP2,HIP1,PRDM1,DSP,FAM162A,TRPS1,IRS2,RNF141,CXCL10,COL22A1,RND3,CSF1,RAP2A,BCL6,SVIL,NCAM1,ERRFI1,AGL,PTPRE,DOCK6,RASGRP1 |
| 1.191e-02 | -4.43 | GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_UP | 191 | 29 | 17377 | 1707 |
VAV3,SYNPO2,AVPI1,SH3BP2,PNRC1,STAT4,AGPAT4,SLC7A2,CHAC1,CLN5,AARS,COL27A1,MCOLN2,RASSF8,HMGCS1,PTPRJ,SLC7A11,KPNA3,GRHL1,EHD3,SLC2A6,RAI14,HK2,P4HA1,ESD,SLFN5,PTGES,SYK,PARP9 |
| 1.191e-02 | -4.43 | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_DN | MSigDB lists | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_DN | 191 | 29 | 17377 | 1707 |
MXI1,PLEKHA8,CRIM1,TES,AGPAT4,CAPN5,PRICKLE1,TUBE1,ATF3,SAV1,HECTD2,BATF3,MAPKAPK2,TMCO3,PMEPA1,PCBP4,MYC,XBP1,ZDHHC23,BMPR1A,PJA1,TMEM37,CSRP2,LRP12,CKAP4,FES,GAB2,HEY1,RRAGD |
| 1.193e-02 | -4.43 | cardiac right ventricle morphogenesis | biological process | GO:0003215 | 21 | 6 | 17256 | 1658 |
GATA3,SMARCD3,SEMA3C,BMPR1A,BMP4,ZFPM2 |
| 1.193e-02 | -4.43 | positive regulation of leukocyte degranulation | biological process | GO:0043302 | 21 | 6 | 17256 | 1658 |
FGR,GATA2,STXBP1,SYK,VAMP8,GAB2 |
| 1.193e-02 | -4.43 | regulation of establishment of cell polarity | biological process | GO:2000114 | 21 | 6 | 17256 | 1658 |
GATA3,GSN,RACK1,RIPOR2,SHTN1,DOCK8 |
| 1.193e-02 | -4.43 | regulation of collateral sprouting | biological process | GO:0048670 | 21 | 6 | 17256 | 1658 |
PTPRS,RND2,BDNF,SPART,FGF13,DCC |
| 1.194e-02 | -4.43 | endoplasmic reticulum subcompartment | cellular component | GO:0098827 | 1049 | 121 | 18223 | 1724 |
CREB3L2,PLA2G4A,ACSL1,ELOVL4,LPCAT2,DNAJC3,XYLT1,ITPR2,CANX,SEZ6L2,LPIN3,ABHD4,CYP26A1,NOS1AP,CDS1,CYP51A1,RTN1,TLR3,ERG28,PDZD8,SEC16B,ERO1B,REEP1,ZDHHC6,SLC10A7,TMED9,PROS1,RASGRP1,ALG10B,CYP1B1,ATL1,ANTXR2,TMEM67,ERGIC1,EVA1A,EBPL,LRRC8B,WLS,CYB5R2,TGFA,JPH1,C3orf52,LRMP,TRAM1L1,HACD1,NFE2L1,RNF125,ASPH,TRIQK,ATP10D,GJC1,INSIG1,RASGRF2,WFS1,PEMT,ERN1,ALG11,CYP2U1,MBOAT2,NR3C2,RETREG1,TYRO3,ALOX5AP,SEC24D,CLGN,CYP2J2,DHCR24,ELOVL7,CYP4V2,UBAC2,CLSTN2,SCD,SPINK5,PGAP1,MYORG,RNF180,GALNT1,BNIP1,SOAT2,MSMO1,FLRT3,SREBF1,SGK1,LMAN2,CERS4,MOXD1,NCEH1,TESPA1,CKAP4,HMGCR,FADS1,B3GLCT,SLC37A1,RNF170,SLC27A2,AGPAT4,MGST3,ELOVL3,GPSM1,RYR2,SHISA2,ARHGAP32,LRAT,ILDR2,HERPUD1,GPR37,EDA,PLOD2,FMO4,MFSD2A,OSBPL5,SRD5A3,XBP1,SQLE,MYRF,PLD1,CERS1,DHCR7,PTGES,OSBPL6,ABCG1 |
| 1.198e-02 | -4.42 | response to nitrogen compound | biological process | GO:1901698 | 1005 | 118 | 17256 | 1658 |
PRKN,SORBS1,ID1,PDE1B,TRIM16,LDLR,ASS1,NPM1,CHUK,STAT5B,ITPR2,ABAT,TLR3,ASNS,TGFBR3,PMAIP1,GSTM3,PDE4D,TLR4,TSHR,SLIT2,PRKACB,GLDC,TRDMT1,FER,TMEM67,SLC3A2,SESN2,ATF4,UROS,ACVR1C,LRRK2,ADCY1,PRKAR2B,AGO4,ABCC2,CD40,SESN1,SNCA,GNAI1,SMAD3,IRS2,GSN,ENPP1,EIF4EBP1,PEMT,WFS1,GNB4,ITGA2,ASIC1,RGS10,MAPK13,KLF5,OXTR,TNFSF4,PPARGC1A,RRAGD,MEF2C,GNG12,INPPL1,GABRB2,IPO5,ATP6V1E2,SELL,GABRG2,NKX6-1,HMGCS1,EEF2,ZNF354A,IGF1R,CA2,BCHE,PRKCD,STC2,GHR,SREBF1,LRP6,INAVA,ADCY6,ERRFI1,PCK2,SYK,CHRM3,DUSP1,PAK1,TRPM4,RHOQ,PXN,GSTM2,NR4A1,RAPGEF2,MGST3,HOMER2,EDEM3,RYR2,MARS,SDK1,TLR6,PLCB1,MGMT,HERPUD1,BAIAP2,CPEB1,GPLD1,CEBPB,TRIB3,FBN1,TERT,GNAO1,XBP1,SH3BP4,RAB31,TBC1D4,TRPC3,CACNA2D1,ATP2B4,LARP1,ATP1A3 |
| 1.199e-02 | -4.42 | L-amino acid transmembrane transporter activity | molecular function | GO:0015179 | 60 | 12 | 17224 | 1680 |
SLC7A1,SERINC5,SLC6A9,SLC7A11,SLC36A1,SERINC2,SLC7A5,SLC36A4,SLC1A3,SLC7A2,SLC1A5,SLC43A1 |
| 1.199e-02 | -4.42 | heart contraction | biological process | GO:0060047 | 83 | 15 | 17256 | 1658 |
SCN5A,KCNN2,SCN1B,CACNB2,ANK2,MAP2K6,FGF12,RYR2,PKP2,KCND3,ATP1B1,ATG5,TPM1,CACNA2D1,GJC1 |
| 1.200e-02 | -4.42 | TAKAYAMA_BOUND_BY_AR | MSigDB lists | TAKAYAMA_BOUND_BY_AR | 10 | 4 | 17377 | 1707 |
MET,SKAP2,CDH2,TES |
| 1.200e-02 | -4.42 | GO_MUSCLE_ATROPHY | MSigDB lists | GO_MUSCLE_ATROPHY | 10 | 4 | 17377 | 1707 |
GSN,PPARGC1A,IL15,MSTN |
| 1.200e-02 | -4.42 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | MSigDB lists | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | 10 | 4 | 17377 | 1707 |
MARCKS,PRKCA,PLCB1,CHRM3 |
| 1.200e-02 | -4.42 | chr1p12 | MSigDB lists | chr1p12 | 10 | 4 | 17377 | 1707 |
SLC22A15,PHGDH,ZNF697,MAGI3 |
| 1.202e-02 | -4.42 | NACHANNEL | prints domains | PR00170 | 10 | 4 | 4652 | 458 |
SCN5A,SCN2A,SCN8A,SCN3A |
| 1.203e-02 | -4.42 | GO_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_CELL_DEATH | 1423 | 165 | 17377 | 1707 |
ACVR1,TRIM2,GRIK2,DNAJC3,GATA3,LILRB1,NPM1,STAT5B,PRKCA,AARS,NOS1AP,F3,TXNDC5,SKI,EPCAM,BAG3,RPS6KA2,PMAIP1,HRK,CTTN,SLIT2,POU3F3,PDGFRB,LAMP3,CYP1B1,ATF4,COL4A3,ACVR1C,WISP3,DCC,LRRK2,DEPTOR,BNIP3L,YAP1,SAV1,SGK2,PYCR1,INHBC,GSN,NCKAP1L,SH3RF1,RASGRF2,PLK2,TNFRSF1A,BMP1,BBC3,ERCC5,UNC5B,NRP1,PPARGC1A,MEF2C,TYRO3,BCL11B,PRKAA2,LATS2,LGALS3,FN1,GABRB2,ITGA6,ST6GAL1,SLK,DHCR24,TNFRSF10C,GAS1,DDIT4,MECOM,SYCP2,BNIP1,IGF1R,MYC,PRELID1,LRP6,BNIP3,STXBP1,ZNF385A,NOS3,HMGCR,BDNF,UNC5C,MSTN,FHL2,OBSCN,STRADB,HIP1,FAM162A,HERPUD1,INHBE,SFN,PLA2G4A,BTC,ID1,COL18A1,NTRK3,TIAM2,SCIN,TLR3,ASNS,BCL6,DAB2IP,STEAP3,MET,PERP,SNAI2,DOCK8,CTH,IGFBP3,PRAME,NKX3-2,ATF3,WNT11,PRKCQ,ATOH1,CD40,FGFR1,SNCA,SMAD3,IRS2,IKZF3,WFS1,TNFSF15,HGF,ATG5,LIFR,ARHGEF11,REL,APBB1,BIK,GAS6,EPHB1,TPD52L1,BEX2,BMP6,MCF2L,PRKCD,SGK3,TFAP2A,SGK1,RRAS2,SMAD6,TNFRSF11A,SPRY2,PNMA2,DUSP1,CARD6,VAV3,SLC40A1,MSX1,RAPGEF2,NUAK2,AGAP2,ZFPM2,MGMT,GPLD1,GPR37,CEBPB,ID3,NACC2,TERT,ACER2,MAP2K6,XBP1,PCGF2,BMP4,DDIT3,TPT1 |
| 1.204e-02 | -4.42 | intrinsic apoptotic signaling pathway | biological process | GO:0097193 | 154 | 24 | 17256 | 1658 |
ATF4,PDK1,EDA2R,CHAC1,STK24,DDIT4,CEBPB,TRIB3,PMAIP1,PRKCD,ERN1,XBP1,TNFRSF1A,TMEM117,BBC3,BNIP3,DAB2IP,FHIT,SCN2A,PERP,DDIT3,ZNF385A,SFN,CYP1B1 |
| 1.204e-02 | -4.42 | ameboidal-type cell migration | biological process | GO:0001667 | 154 | 24 | 17256 | 1658 |
EPB41L5,EFNB2,ITGB7,AMOTL1,PXN,ID1,ACVR1,NR4A1,ARID5B,WNT11,TNS1,OVOL2,PKN1,CENPV,GPLD1,SEMA4F,PKN3,APELA,SEMA3C,NRP1,SEMA3A,SLIT2,CYP1B1,NOS3 |
| 1.204e-02 | -4.42 | DAG and IP3 signaling | REACTOME pathways | R-HSA-1489509 | 34 | 8 | 10287 | 971 |
PDE1B,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PRKCA,PRKACB |
| 1.205e-02 | -4.42 | GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_DN | MSigDB lists | GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_DN | 183 | 28 | 17377 | 1707 |
PLA2G4A,GRB14,ST14,ACVR1C,DSTN,WDFY4,NPC2,CACNB4,DYNC1I1,TTC28,COL27A1,METAP1D,ENTPD1,EPCAM,RNF150,KPNA3,GRHL1,GATA2,MAP2,LHX6,PRELID2,BCL6,SH3BP4,SVIL,HS3ST3B1,NEB,STOM,CHMP4C |
| 1.205e-02 | -4.42 | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_UP | 183 | 28 | 17377 | 1707 |
MOCOS,TMEM65,KIF5A,ST6GAL1,ITGA6,TNFAIP8L2,BNIP3L,TMEM170B,RNF44,SLC46A3,SNX9,SESN1,RAB11FIP5,OTUD1,IGIP,CNKSR3,GPR155,KIAA0513,SVIL,INPP5F,IPCEF1,TLR4,ZFP36L2,PURG,PSPH,FES,DDIT3,MEF2C |
| 1.205e-02 | -4.42 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_DN | 183 | 28 | 17377 | 1707 |
VEGFC,IL32,SH2D2A,GALNT12,ST6GAL1,APBB1,WWC1,LCP2,SKAP1,KCNC4,CA8,KBTBD11,GPR19,PHLDA2,GABARAPL1,TBC1D19,ISG20,FRY,AKAP7,FAT1,WDR19,BCL6,SGK1,MAPK13,PDE4D,MAST4,SPRY2,NOS3 |
| 1.205e-02 | -4.42 | GSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_DN | MSigDB lists | GSE22589_SIV_VS_HIV_AND_SIV_INFECTED_DC_DN | 183 | 28 | 17377 | 1707 |
MSX1,MARK1,DUSP8,KCNQ3,SLC27A2,MYO10,SLC36A1,SCN8A,PTPN13,CCDC110,DHCR24,TCEA3,ZNF605,HIP1,CBS,CEBPA,TNFRSF19,CBLN1,GPR19,ZNF569,CCDC120,MSC,MPPED2,RGS10,NBEA,AGL,PKIA,PNMA2 |
| 1.205e-02 | -4.42 | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | 183 | 28 | 17377 | 1707 |
SH2D2A,NR6A1,REL,LSM11,ATF7IP2,CALCRL,AK4,FAM102B,TMEM170B,BATF,LCP2,EPDR1,F3,HTR7,MAPKAPK2,SLC39A14,INSIG1,KPNA3,SH3BP4,GFI1,FNBP1L,SNX10,SYK,RASGRP1,CEBPD,SLC16A10,DUSP1,FZD1 |
| 1.205e-02 | -4.42 | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 183 | 28 | 17377 | 1707 |
CREB3L2,FGFR4,MN1,RUNX2,ATF4,TDRD3,GALNT6,ARL15,UBAC2,NFE2L1,SHISA2,CHAC1,TCERG1L,PHGDH,SEL1L3,SPIRE1,SYDE2,SLC7A1,RASSF8,FBXO32,SOAT2,ENPP6,CDH17,LMAN2,ESD,CKAP4,IGSF3,DUSP1 |
| 1.205e-02 | -4.42 | GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP | MSigDB lists | GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP | 183 | 28 | 17377 | 1707 |
DMXL2,GCA,LGALS3,MPP1,PTPN6,PSTPIP2,C1orf226,MSR1,LILRB1,MAFB,GSTO1,IL13RA1,LRRC49,FAM198B,TMEM170B,NPC2,ASPH,WARS,EPB41L3,CACHD1,HPSE,GNB4,TSC22D1,RAB31,LIN7A,HS3ST3B1,LIFR,ZNF385A |
| 1.205e-02 | -4.42 | GSE13306_RA_VS_UNTREATED_TCONV_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_TCONV_DN | 183 | 28 | 17377 | 1707 |
MSX1,DNM3,EIF4E3,CHCHD7,FZD4,LITAF,RNF125,CHADL,RAB38,TAF4B,TTLL7,SPINK5,IL18R1,NOS1AP,MAP1B,ENTPD1,KIAA0895,DNAH6,GTSF1,GPR155,GTF2F2,TFAP2A,KCNS3,BMP1,RALGAPA2,MME,CRISPLD1,B4GALT6 |
| 1.205e-02 | -4.42 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN | 183 | 28 | 17377 | 1707 |
ZNF516,MVK,MARK1,IL32,CELSR3,TDRD3,ST6GAL1,PACSIN3,WWC1,COL18A1,CBY1,PLEKHA1,ATP11A,PLEKHB1,TPK1,HEG1,HTR7,FRY,ABI3BP,BNIP3,MAPK13,GRB10,PPP2R2B,ZNF460,MAST4,BARX1,CKAP4,CEBPD |
| 1.205e-02 | -4.42 | GSE3982_BASOPHIL_VS_TH1_UP | MSigDB lists | GSE3982_BASOPHIL_VS_TH1_UP | 183 | 28 | 17377 | 1707 |
MAN2B2,MEIS2,SORBS1,KIF5A,PRDM8,STAT5B,BBS9,ATP10D,RERE,PTPRC,BEX4,SYCP2,FGR,IQCH,ZNF266,PLAGL1,BACH2,BACE2,PRKCB,EMILIN2,BCL6,TSC22D1,SVIL,KLF9,TLR4,PRKACB,PCSK5,DUSP1 |
| 1.205e-02 | -4.42 | enzyme regulator activity | molecular function | GO:0030234 | 1037 | 123 | 17224 | 1680 |
ARHGAP26,PHACTR3,PCSK1N,PPP4R4,FGF13,RASAL2,DOCK1,RECK,C4A,DNAJC3,ARHGAP22,RGS20,NPM1,FAM13A,TBC1D30,DOCK2,TIAM2,SKI,TBC1D19,ADPRHL1,BAG3,SIPA1L2,PPP1R26,CNKSR3,DAB2IP,PPP2R2B,PROS1,PCOLCE2,SERPINH1,RCAN3,SLIT2,RASGRP1,IGFBP3,TBC1D8,TNK2,SESN2,GAPDH,CSN2,COL4A3,LRRK2,ELMOD1,PREX1,PRKAR2B,WNT11,ATP1B1,TBC1D16,SNCA,WARS,CAMK2N1,RANBP2,CXCL10,ARHGAP21,NRG3,GPRC5B,BEX3,NCKAP1L,RGS10,DUSP19,ARHGAP28,SERPINI1,NRP1,SPOCK3,RGS16,ALOX5AP,FN1,STXBP5L,TBC1D1,ARHGEF11,IPO5,OPHN1,ARL2,GAS6,GPSM2,RGS7,SPINK5,GRPEL2,ARHGAP44,PPP2R3A,SYDE2,CHN1,RGS17,CHN2,FRY,FLRT3,PRKCD,SRGAP1,LRP6,RALGAPA2,AFAP1L2,IPCEF1,SH3PXD2B,ERRFI1,TBC1D9,SPRY2,PARP9,BOD1,MOB1B,VAV3,RIN2,ATP5IF1,ARAP2,CRIM1,TBC1D8B,RAPGEF2,ASAP3,GPSM1,RASA3,AGAP2,PHACTR2,ARHGAP32,RACK1,PLCB1,TBC1D2,MMP15,TRIB3,ADGRB3,SH3BP4,TBC1D4,MMP16,TESC,ATP2B4,SFN,PKIA |
| 1.211e-02 | -4.41 | ZU5 | smart domains | SM00218 | 9 | 4 | 9493 | 1056 |
UNC5C,TJP1,UNC5B,ANK2 |
| 1.214e-02 | -4.41 | - | gene3d domains | 2.20.100.10 | 62 | 13 | 8148 | 867 |
ADAMTS17,UNC5C,ADGRB3,WISP3,ADAMTS3,ISM1,THSD4,THSD7B,ADAMTS6,UNC5B,THSD1,HMCN1,ADGRB2 |
| 1.216e-02 | -4.41 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN | 175 | 27 | 17377 | 1707 |
RIN2,VNN2,SERINC5,RPL26,COL6A2,LGR4,TBC1D8B,ITGA6,ACO1,GABRG2,SLITRK5,CACNB4,TPK1,HLF,SH3GL2,PLK2,SLC16A2,MYC,OPN3,SGK1,ACVR2A,LRRK1,TANC2,JAM2,SMYD3,PSPH,RPS23 |
| 1.216e-02 | -4.41 | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 175 | 27 | 17377 | 1707 |
EIF4E3,IL32,RNF144A,MGST3,HOMER2,DHCR24,TCEA3,TCEAL3,CUEDC2,INPP1,ZNF558,DHX32,BATF3,CYP51A1,SFXN1,FSD1,CPNE2,MGAT1,EMILIN2,SQLE,JAKMIP2,BMPR1A,SERPINH1,STXBP1,SFN,CSRP2,CRYL1 |
| 1.218e-02 | -4.41 | V$RORA2_01 | MSigDB lists | V$RORA2_01 | 135 | 22 | 17377 | 1707 |
EPHA3,MEIS2,C1QTNF3,GABRB2,ABAT,KHDRBS2,ASPH,CDR2L,PLEKHH2,KCTD15,SH3GL2,RALGPS2,PCBP4,CHRDL1,B3GALT2,MPP2,BEND4,MARCKS,DBP,TMEFF2,SEMA3A,CTH |
| 1.220e-02 | -4.41 | Steroid biosynthesis | KEGG pathways | ko00100 | 20 | 6 | 7161 | 730 |
SQLE,CYP51A1,SOAT2,DHCR7,MSMO1,DHCR24 |
| 1.220e-02 | -4.41 | Steroid biosynthesis | KEGG pathways | hsa00100 | 20 | 6 | 7161 | 730 |
CYP51A1,SQLE,SOAT2,DHCR7,MSMO1,DHCR24 |
| 1.220e-02 | -4.41 | regulation of pathway-restricted SMAD protein phosphorylation | biological process | GO:0060393 | 61 | 12 | 17256 | 1658 |
INHBC,ACVR1,BMPR2,MSTN,PMEPA1,INHBE,ACVR2A,BMPR1A,BMP4,SMAD6,BMP6,DKK1 |
| 1.224e-02 | -4.40 | ribonucleotide binding | molecular function | GO:0032553 | 1855 | 209 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,RPS6KA2,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,NOS3,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 |
| 1.224e-02 | -4.40 | GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | 167 | 26 | 17377 | 1707 |
ARHGEF11,GABRB2,HEBP1,UBASH3B,ITGA6,C3orf52,NUAK2,MSR1,SELL,PRKCA,MLC1,PAGE5,PFN2,BAG3,CXCL10,RPL12,RASGRF2,FHIT,IPCEF1,TMEM37,APBA2,SEMA3A,TC2N,PRKACB,SLC16A10,RNF152 |
| 1.224e-02 | -4.40 | NOTCH_DN.V1_UP | MSigDB lists | NOTCH_DN.V1_UP | 167 | 26 | 17377 | 1707 |
DLGAP1,MN1,MTG1,SSH3,RUNX2,FGF13,NR6A1,SYT12,SCN8A,ATP8A1,EFNA3,TNS1,P2RY1,ZBBX,MFSD6,INPP1,HPCAL4,SLC9A7,DHX32,FKBP9,PAIP2B,CCNA1,PRKG1,CLMN,NPTXR,RASGRP1 |
| 1.224e-02 | -4.40 | GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | MSigDB lists | GO_MORPHOGENESIS_OF_A_BRANCHING_STRUCTURE | 167 | 26 | 17377 | 1707 |
PAK1,ACVR1,CELSR1,KDM5B,ST14,DCHS1,YAP1,PRDM1,DDR1,FGFR1,RERE,FAT4,MYC,CSF1,SEMA3C,HOXD13,DLX2,BMP4,MET,NRP1,SEMA3A,SPRY2,SLIT2,FOXA1,BTRC,NKX2-1 |
| 1.224e-02 | -4.40 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP | 167 | 26 | 17377 | 1707 |
BCL11B,VNN2,SERINC5,PNRC1,ITGA6,LRMP,YPEL2,ATF7IP2,RASA3,PRKCQ,ATXN7L1,GSN,ABLIM1,AK1,FBXO32,TECPR1,RALGPS2,PELI2,TSC22D1,ZBTB20,IPCEF1,TANC2,APBA2,ZFP36L2,TC2N,RASGRP1 |
| 1.225e-02 | -4.40 | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | 104 | 18 | 17377 | 1707 |
KCNQ3,IGFBP6,AASS,GABRB2,PTPN13,MGST3,OTX1,SLC19A2,DPY19L2,PPFIA2,MYOM2,SH3PXD2B,IQGAP3,VASH2,SUSD4,SCN2A,RPS23,PGBD5 |
| 1.225e-02 | -4.40 | mesoderm development | biological process | GO:0007498 | 122 | 20 | 17256 | 1658 |
EPB41L5,ACVR1,BMPR2,WLS,YAP1,WNT11,ACVR2B,ZFPM2,FGFR1,DKK1,SMAD3,IKZF3,EOMES,APELA,ITGA2,ITGB3,ACVR2A,BMP4,BMPR1A,SIX2 |
| 1.225e-02 | -4.40 | embryonic skeletal system development | biological process | GO:0048706 | 122 | 20 | 17256 | 1658 |
RUNX2,NKX3-2,SATB2,WNT11,KIAA1217,HOXA1,SMAD3,IRX5,WDR19,PCGF2,TFAP2A,ACVR2A,DLX2,BMP4,SHOX2,HOXB9,MMP16,SIX2,MEF2C,PCSK5 |
| 1.226e-02 | -4.40 | postsynaptic specialization membrane | cellular component | GO:0099634 | 34 | 8 | 18223 | 1724 |
GRIK4,CACNG3,GRIK2,GRID1,PTPRS,DLG2,GRIN2D,CDH2 |
| 1.227e-02 | -4.40 | GO_REGULATION_OF_MUSCLE_CONTRACTION | MSigDB lists | GO_REGULATION_OF_MUSCLE_CONTRACTION | 143 | 23 | 17377 | 1707 |
TRPM4,SCN5A,GSTM2,ANK2,PKP2,RYR2,CALCRL,GSTO1,ABAT,ATP1B1,DOCK5,DSP,ASPH,NOS1AP,DSG2,ITGA2,PRKG1,OXTR,PDE4D,CTTN,TPM1,CHRM3,KCNB2 |
| 1.228e-02 | -4.40 | Wnt signaling pathway | biological process | GO:0016055 | 351 | 47 | 17256 | 1658 |
PRKAA2,TNIK,AMOTL1,LGR4,CELSR1,CELSR3,FZD8,LRP4,GATA3,NDRG2,NOTUM,GRK6,KREMEN1,DACT1,MYC,LRP6,PRICKLE2,CPE,SNAI2,GLI1,FZD1,DISC1,MARK1,PTPRU,FZD4,WLS,LRRK2,FERMT2,PRICKLE1,RYR2,AGO4,WNT11,PYGO1,ROR1,PLCB1,GPC6,DKK1,SMAD3,TCF7L1,PTK7,GNAO1,MCC,MAGI2,HOXB9,DDIT3,CTNND2,BTRC |
| 1.228e-02 | -4.40 | cell-cell signaling by wnt | biological process | GO:0198738 | 351 | 47 | 17256 | 1658 |
PRKAA2,TNIK,AMOTL1,LGR4,CELSR1,CELSR3,FZD8,LRP4,NDRG2,GATA3,NOTUM,GRK6,KREMEN1,DACT1,MYC,LRP6,PRICKLE2,CPE,SNAI2,GLI1,FZD1,DISC1,MARK1,FZD4,PTPRU,WLS,LRRK2,PRICKLE1,FERMT2,RYR2,AGO4,WNT11,PYGO1,ROR1,PLCB1,GPC6,DKK1,SMAD3,TCF7L1,GNAO1,PTK7,MCC,HOXB9,MAGI2,DDIT3,BTRC,CTNND2 |
| 1.229e-02 | -4.40 | response to external stimulus | biological process | GO:0009605 | 1854 | 206 | 17256 | 1658 |
ACSL1,DNAJC3,KIF5A,LDLR,LILRB1,ASS1,JCHAIN,GATA3,ENAH,PRKCA,RAC3,STK24,GSDME,BAG3,TYMP,PMAIP1,ITGB3,TLR4,ENO1,ETV1,SLIT2,PDGFRB,NKX2-1,GDAP1,SESN2,MEIS2,ATF4,ACVR1C,DCC,ATOX1,LRRK2,BNIP3L,FEZ1,ABCC2,COTL1,BATF,SESN1,PLEKHB1,GSN,NCKAP1L,ADRB1,TNFRSF1A,SEMA3C,PIK3C2B,NRP1,TNFSF4,UNC5B,PPARGC1A,RRAGD,MEF2C,BCL11B,EFNB2,PRKAA2,GNG12,LGALS3,ITGA6,OPHN1,CHSY1,TNFRSF10C,SLC1A3,ADSSL1,SATB1,FOXG1,DOK5,DDIT4,CHN1,CNTN4,EEF2,SEMA4F,ZNF354A,PDZD7,BCHE,FLRT3,SREBF1,OPN3,INAVA,BNIP3,CADPS2,NCAM1,AGL,GFRA1,RNF152,HMGCR,NOS3,DPYSL5,FADS1,BDNF,UNC5C,VLDLR,EFNA3,RYR2,NPC2,BAIAP2,MAPKAPK2,RIPOR2,MATN2,PLD1,SEMA3A,TRPC3,CXCR5,PRKN,PCSK1N,ELOVL4,CELSR3,IL15,PLXNA2,CHUK,COLEC10,NRXN1,DOCK2,SEMA6A,CTNNA2,CYP26A1,CDS1,TLR3,ASNS,KMO,DAB2IP,PDE4D,MET,SEMA6C,GAB2,FER,EVL,GAPDH,PREX1,ATF3,PRKCQ,WNT11,ATOH1,RAB38,RARRES2,CD40,GABARAPL1,SNCA,BATF3,ISG20,SMAD3,IRS2,CXCL10,NRG3,PTPRJ,TRIM34,GBP1,PEMT,ITGA2,HPGD,GRB10,HGF,ATG5,HOXB9,PSPH,DENND5B,SERINC5,PLSCR4,ROBO2,BMPR2,CMTM8,SELL,KIF5C,CBS,HERC5,GAS6,P2RY1,EPHB1,BMP6,NEO1,FOXP2,HMGCS1,SCN1B,BHLHA15,PRKCD,STC2,ACTA2,PCK2,GFI1,TNFRSF11A,SYK,FES,ATP2B1,PARP9,VEGFC,PDLIM7,TRPM4,VAV3,USP2,NR4A1,NUGGC,NUAK2,LITAF,MARS,TLR6,LRAT,MGMT,PTPRC,CEBPB,FGR,CTSV,XBP1,GRIN2D,BMP4,CMPK2,PTGES,DDIT3,LARP1,TPT1 |
| 1.230e-02 | -4.40 | GNAI1 (G protein subunit alpha i1) | protein interactions | 2770 | 94 | 17 | 17029 | 1718 |
RGS16,PTPRU,KLHL3,GPSM1,RGS20,RASD1,GPSM2,RGS7,GNAI1,RGS17,IGF1R,GNAO1,GNB4,RGS10,SVIL,TSHR,GLI1 |
| 1.230e-02 | -4.40 | GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 151 | 24 | 17377 | 1707 |
DBN1,BCL7A,TRIM2,FAM131C,MGST3,XYLT1,NFIA,CHRNA6,PRKAR2B,GPSM2,SLC12A6,ATP1B1,ADSSL1,GPR137C,ASPH,SPATA7,DDIT4,FKBP9,RALGPS2,PIK3AP1,MPP7,ENTPD7,TMEM86A,MBOAT2 |
| 1.230e-02 | -4.40 | GO_SECOND_MESSENGER_MEDIATED_SIGNALING | MSigDB lists | GO_SECOND_MESSENGER_MEDIATED_SIGNALING | 151 | 24 | 17377 | 1707 |
GSTM2,ANK2,RAPGEF2,LRRK2,RAPGEF4,MCTP2,ADCY1,RYR2,RASD1,GSTO1,ITPR2,ATP1B1,ASPH,PCLO,PPP1R9A,MCU,DDAH1,BHLHA15,PRKG1,ADCY6,PDE4D,RCAN3,RIMS2,NOS3 |
| 1.234e-02 | -4.39 | cofactor biosynthetic process | biological process | GO:0051188 | 221 | 32 | 17256 | 1658 |
NMNAT3,MOCOS,ACSL1,ENO2,ELOVL7,SCD,CHAC1,NUDT12,QPRT,KMO,ALDOC,ENO1,PARP9,ATP5IF1,OPLAH,GAPDH,UROS,PNP,PFKFB2,PANK1,ELOVL3,HACD1,FASN,NFE2L1,OGDHL,TPK1,ALDOA,HK2,BDH2,PGM2L1,HK1,PANK3 |
| 1.236e-02 | -4.39 | Tankyrase_bdg_C | smart domains | SM01319 | 2 | 2 | 9493 | 1056 |
KIAA1671,TNKS1BP1 |
| 1.236e-02 | -4.39 | BCAT.100_UP.V1_UP | MSigDB lists | BCAT.100_UP.V1_UP | 46 | 10 | 17377 | 1707 |
EFEMP1,ENO2,FLVCR2,DNAJC3,BIK,WNT11,SERPINI1,BMP4,HOXA1,DKK1 |
| 1.236e-02 | -4.39 | MCCLUNG_DELTA_FOSB_TARGETS_2WK | MSigDB lists | MCCLUNG_DELTA_FOSB_TARGETS_2WK | 46 | 10 | 17377 | 1707 |
BDNF,GARS,HMGCS1,MGST3,FHL2,GSTO1,SERPINI1,APBA2,FHOD3,MEF2C |
| 1.236e-02 | -4.39 | MODULE_259 | MSigDB lists | MODULE_259 | 46 | 10 | 17377 | 1707 |
PTK7,IL13RA1,ROR1,EPHB6,EPHB1,NRP1,LEPR,PDGFRB,FGFR1,F3 |
| 1.236e-02 | -4.39 | PID_SYNDECAN_1_PATHWAY | MSigDB lists | PID_SYNDECAN_1_PATHWAY | 46 | 10 | 17377 | 1707 |
COL9A3,COL6A2,HPSE,COL4A3,COL4A4,HGF,COL4A5,MET,COL14A1,COL9A2 |
| 1.236e-02 | -4.39 | FKBP7 (FK506 binding protein 7) | protein interactions | 51661 | 26 | 7 | 17029 | 1718 |
GSTO1,HGF,ENO2,ENO1,ALDOC,ALDOA,MYORG |
| 1.236e-02 | -4.39 | PTPRH (protein tyrosine phosphatase, receptor type H) | protein interactions | 5794 | 26 | 7 | 17029 | 1718 |
NBEA,RAB11FIP5,LRP6,PXN,NOS1AP,GHR,C1orf226 |
| 1.236e-02 | -4.39 | ADAM21 (ADAM metallopeptidase domain 21) | protein interactions | 8747 | 26 | 7 | 17029 | 1718 |
CHSY3,ACTA2,EGFL7,PCSK1N,AMIGO1,CANX,PLXNA2 |
| 1.236e-02 | -4.39 | SCGB1D4 (secretoglobin family 1D member 4) | protein interactions | 404552 | 26 | 7 | 17029 | 1718 |
TMEM67,RNF130,COL6A2,BCHE,CNTNAP3,BACE1,CACNA2D1 |
| 1.240e-02 | -4.39 | Hippo signaling pathway | KEGG pathways | ko04390 | 154 | 25 | 7161 | 730 |
MOB1B,LATS2,ID1,BMPR2,FZD4,FZD8,WWC1,YAP1,WNT11,SAV1,BMP6,CTNNA2,PATJ,SMAD3,TCF7L1,MYC,WWTR1,BBC3,DLG2,BMP4,PPP2R2B,BMPR1A,BTRC,SNAI2,FZD1 |
| 1.240e-02 | -4.39 | Hippo signaling pathway | KEGG pathways | hsa04390 | 154 | 25 | 7161 | 730 |
MOB1B,LATS2,ID1,BMPR2,FZD4,FZD8,WWC1,YAP1,WNT11,SAV1,BMP6,CTNNA2,PATJ,SMAD3,TCF7L1,MYC,WWTR1,BBC3,DLG2,BMP4,PPP2R2B,BMPR1A,BTRC,SNAI2,FZD1 |
| 1.240e-02 | -4.39 | GO_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | MSigDB lists | GO_REGULATION_OF_CALCIUM_ION_TRANSPORT_INTO_CYTOSOL | 89 | 16 | 17377 | 1707 |
CXCL10,GSTM2,AKAP5,UBASH3B,PTPN6,ANK2,JPH1,RYR2,TRPC1,GSTO1,BMP4,PDE4D,ATG5,TRPC3,ASPH,SNCA |
| 1.241e-02 | -4.39 | response to cold | biological process | GO:0009409 | 47 | 10 | 17256 | 1658 |
CXCL10,PCSK1N,ZNF516,DNAJC3,ADRB1,SLC25A27,PPARGC1A,YBX3,HSPA2,ATP2B1 |
| 1.243e-02 | -4.39 | negative regulation of oxidative stress-induced cell death | biological process | GO:1903202 | 54 | 11 | 17256 | 1658 |
GPR37,PRKN,ATF4,LRRK2,NCOA7,PDE8A,HGF,RACK1,MET,PYCR1,FZD1 |
| 1.243e-02 | -4.39 | transmission of nerve impulse | biological process | GO:0019226 | 54 | 11 | 17256 | 1658 |
SCN5A,KCNMB4,CACNG3,GRIK2,SCN1B,SCN8A,KCNMB3,AHNAK2,SCN2A,JAM3,SCN3A |
| 1.243e-02 | -4.39 | negative regulation of cellular response to oxidative stress | biological process | GO:1900408 | 54 | 11 | 17256 | 1658 |
GPR37,PRKN,ATF4,LRRK2,NCOA7,PDE8A,HGF,RACK1,MET,PYCR1,FZD1 |
| 1.244e-02 | -4.39 | BCL2L1 (BCL2 like 1) | protein interactions | 598 | 109 | 19 | 17029 | 1718 |
PRKN,BIK,BNIP3L,ZNF219,SNCA,MAPKAPK2,RTN1,SPNS1,IRS2,DOCK7,BNIP1,IKZF3,PMAIP1,BBC3,HRK,BNIP3,ATG5,LARP1,TPT1 |
| 1.245e-02 | -4.39 | skin-upper_leg-malignant_melanoma | COSMIC cancer mutations | skin-upper_leg-malignant_melanoma | 860 | 104 | 17385 | 1698 |
CCDC126,EPHA3,MYCBP2,ELOVL4,PDE1B,CFH,PTPN21,ASS1,PKP2,KIF21B,COL14A1,UBTD2,DOCK2,HMCN1,SLCO3A1,CPNE2,TRPC1,MDH1B,MET,PTPRE,FAM78B,SLIT2,KCNB2,DOCK8,SNAI2,FER,DCC,CYB5R2,ANK2,SHANK2,NFIA,ADCY1,TNS1,PYGO1,ATP10D,METAP1D,TMEM132B,SMAD3,PTPRJ,ENPP6,PTK7,CCBE1,ABI3,LAMB1,PTPRS,SEMA3C,INPP5F,KLHL31,STON2,HS6ST3,DYRK3,MRC2,STXBP5L,PTPRD,ZHX3,TSPAN15,ATP9A,ZNF25,GABRB2,EPS8,MCTP2,HERC5,CREB5,EPHB1,PPP2R3A,FUT9,ZIC5,FAM107B,LIMCH1,TOX,LOXL4,CHRM3,MED12L,RIMS2,NOS3,PARP9,VAV3,SYNPO2,KCNQ3,BTNL9,TBC1D8B,SPATA6,PTPN13,OGDHL,WWC1,PEX5L,SHISA2,PLCB1,KHDRBS2,PTPRC,GRIK4,PLEKHH2,ADAMTS3,FBN1,PLXDC2,C1orf21,CLMN,PTPRN2,MYOM2,PLD1,CRISPLD1,CACNA2D1,LARP1,ACSM3 |
| 1.247e-02 | -4.38 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-non_functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-non_functioning | 226 | 33 | 17385 | 1698 |
DOC2A,EDA2R,MSR1,FAM13A,RGS7,TNKS1BP1,PCDHB14,MCOLN2,COL22A1,GRHL1,JAKMIP2,MYH15,MET,ZNF391,COL4A3,ABCC4,SPOCD1,DCC,TRAM1L1,FASN,OBSCN,ZNF558,JAM3,PYCR1,MAP1B,PTPRJ,ENPP6,TERT,NXPH4,SEMA3C,ZNF808,TANC2,DOCK9 |
| 1.256e-02 | -4.38 | GO_RECEPTOR_MEDIATED_ENDOCYTOSIS | MSigDB lists | GO_RECEPTOR_MEDIATED_ENDOCYTOSIS | 200 | 30 | 17377 | 1707 |
PDLIM7,PRSS12,SYT12,VLDLR,LDLR,OPHN1,MSR1,LILRB1,CALCRL,HIP1,CANX,MLC1,SNX9,NEDD4,SNCA,ENPP1,SH3GL2,FCHO2,GHR,RAB31,LRP6,INPP5F,LOXL4,CTTN,PACSIN1,FNBP1L,LRP3,STON2,SYK,LRP12 |
| 1.258e-02 | -4.38 | Response to antipsychotic treatment(PMID:20195266) | GWAS genes | Response to antipsychotic treatment(PMID:20195266) | 13 | 6 | 2388 | 399 |
CLMN,PRKAR2B,MEIS2,RNF144A,FHOD3,ATF7IP2 |
| 1.260e-02 | -4.37 | Opioid Signalling | REACTOME pathways | R-HSA-111885 | 85 | 15 | 10287 | 971 |
PLA2G4A,GNG12,PDE1B,GNB4,GNAO1,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PDE4D,PRKCA,PLCB1,PRKACB,GNAI1 |
| 1.264e-02 | -4.37 | MYOC (myocilin) | protein interactions | 4653 | 45 | 10 | 17029 | 1718 |
ACTA2,VIM,GAPDH,LGALS3,TPM1,FN1,ENO1,FBN1,ALDOA,TNFRSF1A |
| 1.264e-02 | -4.37 | ACVR1B (activin A receptor type 1B) | protein interactions | 91 | 45 | 10 | 17029 | 1718 |
SMAD3,INHBC,ACVR1,BMPR2,TSC22D1,ACVR2A,ACVR2B,SMAD6,TSPAN17,PRKACB |
| 1.265e-02 | -4.37 | GCM_MAP1B | MSigDB lists | GCM_MAP1B | 60 | 12 | 17377 | 1707 |
TMEM237,PTPRD,RBFOX2,KIF5C,DIRAS1,CDC42BPA,NCAM1,BEX2,KIF1B,BTRC,SPIRE1,MAP1B |
| 1.265e-02 | -4.37 | GO_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT | MSigDB lists | GO_REGULATION_OF_NEUROTRANSMITTER_TRANSPORT | 60 | 12 | 17377 | 1707 |
RAB3B,KCNMB4,UNC13B,SYT12,LRRK2,SEPT5,KCNC4,STXBP1,PFN2,PPP1R9A,MEF2C,SNCA |
| 1.265e-02 | -4.37 | GO_TRANSMISSION_OF_NERVE_IMPULSE | MSigDB lists | GO_TRANSMISSION_OF_NERVE_IMPULSE | 53 | 11 | 17377 | 1707 |
SCN5A,KCNMB4,CACNG3,SCN1B,GRIK2,SCN8A,KCNMB3,SCN2A,CACNB4,JAM3,SCN3A |
| 1.265e-02 | -4.37 | V$PAX2_01 | MSigDB lists | V$PAX2_01 | 53 | 11 | 17377 | 1707 |
FOXP2,MAP1A,IKZF5,PDZD7,PRDM13,PDE10A,UBASH3B,BEND4,SFXN3,NKX2-8,FOXG1 |
| 1.265e-02 | -4.37 | GO_ALPHA_BETA_T_CELL_ACTIVATION | MSigDB lists | GO_ALPHA_BETA_T_CELL_ACTIVATION | 53 | 11 | 17377 | 1707 |
BCL11B,CEBPB,EOMES,IL15,GATA3,TNFSF4,BATF,SATB1,DOCK2,SYK,IL18R1 |
| 1.265e-02 | -4.37 | IKEDA_MIR1_TARGETS_UP | MSigDB lists | IKEDA_MIR1_TARGETS_UP | 53 | 11 | 17377 | 1707 |
EFNB2,BDNF,ARHGAP21,ACVR1,GPRC5B,CRIM1,PLK2,FNDC3A,ZFP36L2,PRKACB,CPEB1 |
| 1.265e-02 | -4.37 | BROWNE_HCMV_INFECTION_10HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_10HR_DN | 53 | 11 | 17377 | 1707 |
BDNF,RIN2,FRY,RHOBTB1,SCN8A,RGS20,TTC30A,KLF9,FBXL2,ETV1,MTUS1 |
| 1.266e-02 | -4.37 | Ras protein signal transduction | biological process | GO:0007265 | 247 | 35 | 17256 | 1658 |
CELSR1,ARHGEF11,RHOBTB1,RHOD,PAK5,EPS8,DHCR24,CHUK,GPSM2,RAC3,RND2,CNKSR3,RAP2A,RAB26,BCL6,IPCEF1,IQGAP3,RAB27B,RRAS2,RASGRP1,PAK1,RAB3B,RHOQ,RAB6B,RAPGEF2,RAB38,SYNJ2BP,MAPKAPK2,RND3,PLK2,RAB31,PLD1,SHTN1,RAB30,HACE1 |
| 1.266e-02 | -4.37 | ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN | MSigDB lists | ZHENG_FOXP3_TARGETS_IN_T_LYMPHOCYTE_DN | 33 | 8 | 17377 | 1707 |
PTPRC,BCL11B,BACH2,TRIM34,ST8SIA1,CPE,SATB1,GFI1 |
| 1.266e-02 | -4.37 | chr8p22 | MSigDB lists | chr8p22 | 33 | 8 | 17377 | 1707 |
CHRNA6,TEX15,TNFRSF10C,SLC7A2,LZTS1,RIMS2,MSR1,MTUS1 |
| 1.266e-02 | -4.37 | GO_GLUTATHIONE_TRANSFERASE_ACTIVITY | MSigDB lists | GO_GLUTATHIONE_TRANSFERASE_ACTIVITY | 33 | 8 | 17377 | 1707 |
GDAP1,GSTM2,ALOX5AP,GSTO2,MGST3,GSTM4,GSTM3,GSTO1 |
| 1.266e-02 | -4.37 | ROZANOV_MMP14_TARGETS_DN | MSigDB lists | ROZANOV_MMP14_TARGETS_DN | 33 | 8 | 17377 | 1707 |
RTN1,PGM2L1,RGS17,VWA5A,SNTB1,ZDHHC14,ZHX3,PLXDC2 |
| 1.268e-02 | -4.37 | regulation of biomineral tissue development | biological process | GO:0070167 | 76 | 14 | 17256 | 1658 |
TRPM4,SMAD3,ENAM,ENPP1,ACVR1,BMPR2,TFAP2A,ACVR2A,BMPR1A,GAS6,ACVR2B,BMP4,BMP6,MEF2C |
| 1.268e-02 | -4.37 | V$GCM_Q2 | MSigDB lists | V$GCM_Q2 | 225 | 33 | 17377 | 1707 |
RIMKLA,BLVRB,BTBD9,CADM2,OVOL2,CHD5,SPEG,ZNF362,IGF1R,COL25A1,PCBP4,LHX6,EIF1,TSC22D1,CNNM2,SMAD6,TMEM56,BDNF,PANK1,WWC1,SLITRK5,PRDM1,ILDR2,TCF7L1,PTPRJ,KLF12,GNAO1,B3GALT2,KLF5,PLD1,CERS1,MLLT3,HEY1 |
| 1.271e-02 | -4.37 | Ras signaling pathway | KEGG pathways | hsa04014 | 226 | 34 | 7161 | 730 |
PLA2G4A,GNG12,RASAL2,FGF13,PAK5,REL,CHUK,PRKCA,RAC3,IGF1R,MET,RRAS2,RAPGEF5,PRKACB,RASGRP1,PDGFRB,GAB2,VEGFC,PAK1,FGFR4,EFNA3,FGF12,RASA3,FGF17,FGFR1,HTR7,PRKCB,GNB4,AKT3,CSF1,RASGRF2,HGF,PLD1,MAPK10 |
| 1.272e-02 | -4.36 | regulation of cation transmembrane transport | biological process | GO:1904062 | 299 | 41 | 17256 | 1658 |
SCN5A,CACNG3,UBASH3B,HECW2,CACNB4,NEDD4,NOS1AP,LRRC55,KCNAB1,KCNN2,SCN1B,CACNB2,EHD3,TRPC1,TSPAN13,PDE4D,HSPA2,ALG10B,DPP10,KCNIP3,GSTM2,ANK2,PTPN6,SHANK2,JPH1,FGF12,RYR2,GSTO1,AMIGO1,ATP1B1,SNCA,CXCL10,KCNG1,GEM,ATG5,PPARGC1A,TESC,CACNA2D1,ATP2B4,STOM,MEF2C |
| 1.272e-02 | -4.36 | Retrograde endocannabinoid signaling | KEGG pathways | ko04723 | 101 | 18 | 7161 | 730 |
GNG12,GABRB2,ADCY1,GABRG2,GABRR2,ITPR2,PRKCA,PLCB1,ABHD6,GNAI1,DAGLA,PRKCB,GNAO1,GNB4,ADCY6,MAPK13,MAPK10,PRKACB |
| 1.272e-02 | -4.36 | Retrograde endocannabinoid signaling | KEGG pathways | hsa04723 | 101 | 18 | 7161 | 730 |
GNG12,GABRB2,ADCY1,GABRG2,GABRR2,ITPR2,PRKCA,PLCB1,ABHD6,GNAI1,DAGLA,PRKCB,GNAO1,GNB4,ADCY6,MAPK13,MAPK10,PRKACB |
| 1.272e-02 | -4.36 | organic hydroxy compound metabolic process | biological process | GO:1901615 | 423 | 55 | 17256 | 1658 |
PRKAA2,PRKN,NUDT10,MVK,INPPL1,PDE1B,LDLR,DHCR24,CYP4V2,GATA3,BTBD9,CEBPA,ISYNA1,INPP1,CYP26A1,CYP51A1,RNF180,IDI1,HMGCS1,ERG28,SOAT2,MSMO1,SREBF1,TRPC1,PCK2,MOXD1,PLTP,HMGCR,CYP1B1,ALDH2,EBPL,SLC27A2,PFKFB2,MVD,CYB5R2,VLDLR,GDPD1,NFE2L1,NPC2,PLCB1,LRAT,LEPR,FGFR1,SNCA,GPR37,INSIG1,ACER2,SRD5A3,OSBPL5,INPP4B,MAOA,SQLE,DHCR7,OSBPL6,ABCG1 |
| 1.274e-02 | -4.36 | RAB3IP (RAB3A interacting protein) | protein interactions | 117177 | 87 | 16 | 17029 | 1718 |
PDLIM7,PHLDB2,DCDC1,FAM124A,PFKFB2,PLEKHA5,CBY1,FAM110B,BAIAP2,TXNDC5,RASSF8,NUMBL,CCDC146,SH3BP4,SFN,GAB2 |
| 1.275e-02 | -4.36 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | 192 | 29 | 17377 | 1707 |
BCL11B,EHHADH,CRIM1,RAB6B,MPP1,ATP8A1,CYP2J2,PTPN13,NDRG2,ITPR2,ATP1B1,SATB1,CBLN1,ARHGEF10L,PRKCB,PMEPA1,HEYL,DSG2,EHD3,XBP1,ADCY6,SH3BGRL2,DBP,RCAN3,RRAS2,GFI1,TMEM120B,DOCK6,CTNND2 |
| 1.275e-02 | -4.36 | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | 192 | 29 | 17377 | 1707 |
FARP1,MRC2,CELSR1,FN1,AGPAT4,DHCR24,NDRG2,PRKAR2B,RAB38,TBC1D16,ABHD6,FAM162A,TBC1D2,ARHGEF10L,FGR,PPP1R26,NACC2,KMO,PRCP,CSF1,RAB31,P4HA1,MAOA,CTTN,PCOLCE2,STXBP1,SPRY2,FES,CKAP4 |
| 1.275e-02 | -4.36 | GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION | MSigDB lists | GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION | 192 | 29 | 17377 | 1707 |
EPB41L5,MSX1,CELSR1,BMPR2,WLS,OTX1,RGS20,PLXNA2,ACVR2B,PGAP1,PPP2R3A,SKI,DKK1,SMAD3,PCGF2,ACVR2A,LRP6,SEMA3C,HOXD13,BMPR1A,BMP4,HOXB9,BARX1,MLLT3,COBL,DDIT3,SIX2,PCSK5,PCSK6 |
| 1.288e-02 | -4.35 | canonical Wnt signaling pathway | biological process | GO:0060070 | 99 | 17 | 17256 | 1658 |
LGR4,PTPRU,FZD4,FZD8,LRRK2,RYR2,GATA3,WNT11,SMAD3,TCF7L1,MYC,PTK7,LRP6,HOXB9,SNAI2,FZD1,GLI1 |
| 1.289e-02 | -4.35 | V$LMO2COM_01 | MSigDB lists | V$LMO2COM_01 | 242 | 35 | 17377 | 1707 |
ANKRD13B,ID1,RIMKLA,TJP1,PKN1,SEMA6A,CYP26A1,MTUS1,SPEG,NUMBL,LRRN1,UNC13B,GATA2,BCL6,ZNF521,MAP7,NBEA,CNNM2,TSPAN13,GFRA1,B4GALT6,GAB2,FGF12,WWC1,AGAP2,ATP1B1,PTPRJ,FGR,MYADM,RPL28,DLG2,PAX9,CDH2,NR3C2,DOCK9 |
| 1.290e-02 | -4.35 | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-spleen-lymphoid_neoplasm-marginal_zone_lymphoma | 329 | 45 | 17385 | 1698 |
ARHGAP26,CCDC148,AMOTL1,SORBS1,ROBO2,PTPRD,KIF5A,ADSSL1,DDX60L,COL27A1,FHOD3,TXNRD3,GALNT1,PDZD8,TACC2,GAS2L3,BCL6,LRP6,ADCY6,PLTP,GPR161,PRKACB,CDH26,PCDH10,BCL7A,MEIS2,EIF4E3,SLITRK2,DCDC1,PARD3B,CACNA1E,OBSCN,AK4,PHACTR2,SDK1,CRYBG3,EML1,TEX15,FAT4,PELI2,FAT1,HPGD,HGF,DISP1,CACNA2D1 |
| 1.292e-02 | -4.35 | GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_UP | MSigDB lists | GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_UP | 184 | 28 | 17377 | 1707 |
FN1,CYB5R2,CD276,DHCR24,OTX1,ACO1,FASN,PKP2,PRKAR2B,FGF17,GALNT14,DENND3,KHDRBS2,TXNRD3,PCDH7,CYP51A1,RSL24D1,IKZF3,MARVELD2,RBPMS2,PRELID2,PJA1,MET,ETV1,ENO1,DHCR7,RAPGEF5,FZD1 |
| 1.292e-02 | -4.35 | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_UP | MSigDB lists | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_UP | 184 | 28 | 17377 | 1707 |
CXCR5,ARHGAP26,SESN2,RUNX2,LGALS3,SIDT1,RECK,AGPAT4,MCTP2,PREX1,FHL2,KCTD12,USP30,FAM174B,IKZF2,SMPDL3B,HOPX,CAMK2N1,GPR15,IKZF3,SEMA4F,ZNF354A,SOAT2,GPR160,DSG2,GFI1,FOXA1,RBMS2 |
| 1.292e-02 | -4.35 | GSE3982_BCELL_VS_TH1_DN | MSigDB lists | GSE3982_BCELL_VS_TH1_DN | 184 | 28 | 17377 | 1707 |
GPR63,MRC2,FN1,ATP9A,MPP1,ZCCHC24,EXOC6B,AK4,CBS,PHACTR2,CEBPA,HBE1,RNF24,WNT11,SCD,STEAP1,QPRT,HOPX,RAB11FIP5,SFXN1,ITGA2,KCNS3,SLC6A15,CTTN,IPCEF1,NRP1,SPRY2,ATP2B4 |
| 1.292e-02 | -4.35 | GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | 184 | 28 | 17377 | 1707 |
PAK1,FADS1,EDEM3,CYP4V2,OPHN1,PRRG1,TTYH2,GPR180,ABHD4,EYA4,TBC1D2,RAB11FIP5,NSD1,GSN,EPB41L3,TLR3,NACC2,IGIP,GAS2L3,GAN,TSC22D1,BEND4,RNF130,TBC1D9,LRRC27,GATM,PURG,SMPDL3A |
| 1.292e-02 | -4.35 | GSE34515_CD16_POS_MONOCYTE_VS_DC_DN | MSigDB lists | GSE34515_CD16_POS_MONOCYTE_VS_DC_DN | 184 | 28 | 17377 | 1707 |
FER,ANTXR2,SLC40A1,ALOX5AP,TCP11L2,PSTPIP2,MPP1,ATP8A1,CYP4V2,BNIP3L,RABAC1,WDFY4,SLC46A3,GDPD5,RNF150,CXCL10,TIFA,FCHO2,PIK3AP1,NCKAP1L,PELI2,TMEM86A,FAM107B,GSTM3,DBP,FAM84B,PCK2,B4GALT6 |
| 1.292e-02 | -4.35 | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_DN | 184 | 28 | 17377 | 1707 |
VNN2,SSH3,GCA,TUBA1A,SMAD9,NR6A1,ZCCHC24,LITAF,NRN1,OVOL2,TNFRSF10C,APBA1,EPHB1,GALNT14,TLR6,TXNRD3,CEBPB,RNF141,GSN,RPS6KA2,KCTD15,SLC7A11,FUT9,LHX6,IL9R,RAPGEF5,SYK,CEBPD |
| 1.301e-02 | -4.34 | REACTOME_L1CAM_INTERACTIONS | MSigDB lists | REACTOME_L1CAM_INTERACTIONS | 82 | 15 | 17377 | 1707 |
PAK1,SCN5A,RPS6KA2,SH3GL2,KCNQ3,SCN1B,SCN8A,ITGA2,ITGB3,LAMB1,SCN2A,NRP1,NCAM1,FGFR1,CNTN1 |
| 1.301e-02 | -4.34 | MODULE_274 | MSigDB lists | MODULE_274 | 82 | 15 | 17377 | 1707 |
HTR7,DOC2A,KCNQ3,SCN1B,GRIK2,KIF5A,GABRG2,ABAT,SLC1A3,SNAP25,APBA1,NCAM1,NOVA1,CBLN1,CHRM3 |
| 1.301e-02 | -4.34 | GUO_HEX_TARGETS_UP | MSigDB lists | GUO_HEX_TARGETS_UP | 82 | 15 | 17377 | 1707 |
RTN1,IGF1R,FZD4,PTPN13,TES,WWTR1,PCGF2,EFNA3,KLF9,BMP4,WWC2,NRP1,SATB1,LIFR,RRAGD |
| 1.304e-02 | -4.34 | HormR | smart domains | SM00008 | 24 | 7 | 9493 | 1056 |
CALCRL,ADGRB3,CELSR1,CELSR3,ADGRL2,ADGRB2,ADGRL1 |
| 1.306e-02 | -4.34 | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | 176 | 27 | 17377 | 1707 |
SUSD3,ACVR1,EVL,GALNT12,GATA3,PHACTR2,PRKCQ,STAT5B,ISYNA1,RPL34,DEXI,SFXN1,BAG3,KLF12,RASGRF2,FAAH2,FAM107B,INPP4B,ST8SIA1,FAM84B,RCAN3,MAST4,MLLT3,TC2N,RASGRP1,DOCK9,PHC1 |
| 1.306e-02 | -4.34 | GSE3982_MAST_CELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_BASOPHIL_DN | 176 | 27 | 17377 | 1707 |
ARAP2,EVL,ALOX5AP,ZNF395,GRIK2,DNAJC3,BEGAIN,STAT5B,APBA1,CA8,DENND3,SATB1,SLCO3A1,ATP10D,CPEB1,RPL34,ISG20,PTPRC,SFXN1,BACH2,PMAIP1,RAB31,SEMA3C,HGF,PDE4D,PTGES,DUSP1 |
| 1.306e-02 | -4.34 | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_DN | 176 | 27 | 17377 | 1707 |
DPP10,UNC5C,ARAP2,IL15,MYO10,REL,RAPGEF2,STAT4,COBLL1,AK4,CHAC1,BATF,HERC6,PGAP1,DDX60L,WARS,GALNT3,CXCL10,INSIG1,GRHL1,MFSD2A,CNKSR3,OXTR,CMPK2,JAM2,KIAA1211,DUSP1 |
| 1.306e-02 | -4.34 | GO_LOCOMOTORY_BEHAVIOR | MSigDB lists | GO_LOCOMOTORY_BEHAVIOR | 176 | 27 | 17377 | 1707 |
USP2,CELSR1,PDE1B,FZD4,LRRK2,EPS8,MCOLN3,FGF12,BTBD9,ABAT,SNAP25,APBA1,CACNB4,NOVA1,ZIC1,SNCA,NEGR1,GPR37,GPRC5B,GNAO1,RASD2,GRIN2D,FIG4,APBA2,ZNF385A,ATP1A3,NKX2-1 |
| 1.309e-02 | -4.34 | human chr13q33.3 | chromosome location | human chr13q33.3 | 13 | 4 | 26185 | 1967 |
EFNB2,FAM155A,TNFSF13B,ABHD13 |
| 1.309e-02 | -4.34 | human chr7q21.13 | chromosome location | human chr7q21.13 | 13 | 4 | 26185 | 1967 |
CFAP69,STEAP1,CLDN12,FZD1 |
| 1.310e-02 | -4.34 | Toll_tir_struct_dom_sf | interpro domains | IPR035897 | 27 | 7 | 18492 | 1811 |
IL17RD,TLR3,TLR6,PIK3AP1,TLR4,IL1RAP,IL18R1 |
| 1.312e-02 | -4.33 | MODULE_6 | MSigDB lists | MODULE_6 | 397 | 53 | 17377 | 1707 |
COL9A3,TRIM2,FN1,CFH,IGFBP6,TRIM16,RHOD,ATP9A,ST6GAL1,ITGA6,UGDH,LDLR,ZIC2,DDR1,PHLDA2,GAS1,F3,MTUS1,DDIT4,EPCAM,ABLIM1,CFHR1,SMTN,BCL6,SERPINH1,CPE,HSPA2,GATM,SLIT2,PDGFRB,IGFBP3,CYP1B1,CD55,COL6A2,PTPRU,CRIM1,NR4A1,PTPN13,ATF3,RARRES2,DSP,FGFR1,PTPRC,HLF,WWTR1,RAB31,BMP1,MAOA,PTPRN2,KLF5,DBP,GEM,TPM1 |
| 1.315e-02 | -4.33 | WWC2 (WW and C2 domain containing 2) | protein interactions | 80014 | 15 | 5 | 17029 | 1718 |
WWC1,LATS2,WWC2,PRKCA,PTPN21 |
| 1.315e-02 | -4.33 | CPEB1 (cytoplasmic polyadenylation element binding protein 1) | protein interactions | 64506 | 15 | 5 | 17029 | 1718 |
MAP2,KIF1B,CPEB1,METAP1D,GAN |
| 1.315e-02 | -4.33 | IL32 (interleukin 32) | protein interactions | 9235 | 15 | 5 | 17029 | 1718 |
RPL4,ZFPM2,IL32,PRKCD,BCL6 |
| 1.315e-02 | -4.33 | PPFIA2 (PTPRF interacting protein alpha 2) | protein interactions | 8499 | 15 | 5 | 17029 | 1718 |
PTPRS,PTPRD,PPFIA2,PPFIBP1,PPFIBP2 |
| 1.317e-02 | -4.33 | HSPB6 (heat shock protein family B (small) member 6) | protein interactions | 126393 | 10 | 4 | 17029 | 1718 |
BAG3,MAP1B,SNCA,PNMA2 |
| 1.317e-02 | -4.33 | AKAP6 (A-kinase anchoring protein 6) | protein interactions | 9472 | 10 | 4 | 17029 | 1718 |
RYR2,DISC1,PDE4D,MYC |
| 1.317e-02 | -4.33 | SH3YL1 (SH3 and SYLF domain containing 1) | protein interactions | 26751 | 10 | 4 | 17029 | 1718 |
BAG3,VIM,PIK3C2B,ERRFI1 |
| 1.317e-02 | -4.33 | LRCH1 (leucine rich repeats and calponin homology domain containing 1) | protein interactions | 23143 | 10 | 4 | 17029 | 1718 |
SMAD3,MOB1B,DOCK7,DOCK8 |
| 1.317e-02 | -4.33 | KCNQ5 (potassium voltage-gated channel subfamily Q member 5) | protein interactions | 56479 | 10 | 4 | 17029 | 1718 |
DISC1,KCNQ3,MCOLN3,KCNS3 |
| 1.317e-02 | -4.33 | pancreatic_intraepithelial_neoplasia_(PanIN) | COSMIC cancer mutations | pancreatic_intraepithelial_neoplasia_(PanIN) | 687 | 85 | 17385 | 1698 |
PLA2G4A,GRIK2,PPFIBP2,HECW2,COL18A1,C20orf194,SLC2A13,ABAT,COL14A1,PPP1R9A,HMCN1,BAG3,ZNF362,DNAH6,SLC16A2,FAAH2,KAZN,ZNF521,MAP7,RTKN2,MARCKS,WWC2,SCN2A,JAKMIP3,THSD1,ENO1,NEB,ABCC4,PTPRU,CR2,NT5DC2,HTR7,ARMC4,SH3RF1,ARHGAP28,TANC2,SUSD4,DNHD1,COBL,LZTS1,CTNND2,SV2B,LRFN5,FN1,ZNF25,UBASH3B,EPS8,LRP4,P2RY1,WDFY4,PKN1,SPINK5,DYNC1I1,PGAP1,FSD1,APLF,FRAS1,PRICKLE2,ST8SIA1,SLCO4C1,COL9A2,VAV3,RIN2,LRRIQ1,GSTM4,RYR2,TTYH2,OBSCN,WWC1,C1R,ARHGAP32,ATP11A,SNTB1,FNDC3A,LDHD,GLCE,DPY19L2,TMCO3,NSD1,OR2T33,RND3,ZNF214,SFMBT1,ATP2B4,FOXA1 |
| 1.317e-02 | -4.33 | pancreas-pancreatic_intraepithelial_neoplasia_(PanIN) | COSMIC cancer mutations | pancreas-pancreatic_intraepithelial_neoplasia_(PanIN) | 687 | 85 | 17385 | 1698 |
PLA2G4A,GRIK2,PPFIBP2,HECW2,COL18A1,C20orf194,SLC2A13,ABAT,COL14A1,PPP1R9A,HMCN1,BAG3,ZNF362,DNAH6,SLC16A2,FAAH2,KAZN,ZNF521,MAP7,RTKN2,MARCKS,WWC2,SCN2A,JAKMIP3,THSD1,ENO1,NEB,ABCC4,PTPRU,CR2,NT5DC2,HTR7,ARMC4,SH3RF1,ARHGAP28,TANC2,SUSD4,DNHD1,COBL,LZTS1,CTNND2,SV2B,LRFN5,FN1,ZNF25,UBASH3B,EPS8,LRP4,P2RY1,WDFY4,PKN1,SPINK5,DYNC1I1,PGAP1,FSD1,APLF,FRAS1,PRICKLE2,ST8SIA1,SLCO4C1,COL9A2,VAV3,RIN2,LRRIQ1,GSTM4,RYR2,TTYH2,OBSCN,WWC1,C1R,ARHGAP32,ATP11A,SNTB1,FNDC3A,LDHD,GLCE,DPY19L2,TMCO3,NSD1,OR2T33,RND3,ZNF214,SFMBT1,ATP2B4,FOXA1 |
| 1.320e-02 | -4.33 | CaM pathway | REACTOME pathways | R-HSA-111997 | 28 | 7 | 10287 | 971 |
ADCY6,PRKAR2B,PDE1B,PRKCA,PRKCD,PRKACB,ADCY1 |
| 1.320e-02 | -4.33 | Calmodulin induced events | REACTOME pathways | R-HSA-111933 | 28 | 7 | 10287 | 971 |
ADCY6,PRKAR2B,PDE1B,PRKCA,PRKCD,PRKACB,ADCY1 |
| 1.322e-02 | -4.33 | GO_HINDBRAIN_DEVELOPMENT | MSigDB lists | GO_HINDBRAIN_DEVELOPMENT | 136 | 22 | 17377 | 1707 |
SCN5A,SMAD9,FZD4,RBFOX2,WLS,OTX1,PLXNA2,NLGN4X,MAFB,ABAT,NRXN1,AARS,CBLN1,CTNNA2,RERE,FOXP2,GATA2,PTPRS,LRP6,PPARGC1A,GLI1,CNTN1 |
| 1.322e-02 | -4.33 | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | 136 | 22 | 17377 | 1707 |
PRKAA2,AASS,KLHL3,ESRRG,SLK,GSTM4,SHANK2,C1orf226,ADCY1,BCAN,B4GALNT3,PCLO,GABARAPL1,ZNF711,IGF1R,ABCA5,DSG2,GHR,MPPED2,KLF9,TBC1D9,CTH |
| 1.324e-02 | -4.32 | GO_CHONDROCYTE_DEVELOPMENT | MSigDB lists | GO_CHONDROCYTE_DEVELOPMENT | 21 | 6 | 17377 | 1707 |
CHSY1,RUNX2,SERPINH1,BMPR2,SHOX2,COL27A1 |
| 1.324e-02 | -4.32 | PATJ (PATJ, crumbs cell polarity complex component) | protein interactions | 10207 | 52 | 11 | 17029 | 1718 |
LATS2,SCN5A,GJB2,LIN7A,WWC1,YAP1,GRIN2D,SAV1,KIF1B,HOMER3,SNCA |
| 1.325e-02 | -4.32 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_72H_ACT_CD4_TCELL_UP | 160 | 25 | 17377 | 1707 |
PLA2G4A,SERINC5,MGST3,HOMER2,OGDHL,KIAA1324L,TTC30A,GATA3,SETBP1,RNF125,NDFIP2,CACNB4,IKZF2,GNAI1,RASSF8,MAGEA12,ZBTB38,PLEKHH2,EOMES,MYO3B,MAOA,RAB27B,ZNF488,IGSF3,GAB2 |
| 1.325e-02 | -4.32 | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_CTNNB1_DN | 160 | 25 | 17377 | 1707 |
VNN2,LGALS3,STAT4,TNFSF13B,WWC1,KCTD12,SLC7A2,ARRDC4,SEL1L3,SEMA6A,F3,EFEMP1,BACE2,MCC,INHBE,RALGAPA2,HPGD,SLC22A15,GEM,RAB27B,TNFSF4,MOXD1,PLTP,RASGRP1,GLDC |
| 1.325e-02 | -4.32 | GO_LYASE_ACTIVITY | MSigDB lists | GO_LYASE_ACTIVITY | 160 | 25 | 17377 | 1707 |
MOCOS,ALOX5AP,EHHADH,ENO2,UROS,MVD,ADCY1,ACO1,FASN,CBS,GUCY1A2,TGDS,CA8,CA13,CENPV,CA2,APLF,ALDOC,ALDOA,PAM,ADCY6,PCK2,ENO1,CTH,GLDC |
| 1.325e-02 | -4.32 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | 160 | 25 | 17377 | 1707 |
SERINC5,PNRC1,SIDT1,UROS,EXOC6B,TCEA3,NFIA,CYP4V2,TTYH2,NDRG2,SORBS3,AMIGO1,PRKCA,SKAP1,SLC46A3,BEX2,ADAMTS17,BEX4,ZBTB38,MPP7,ZBTB20,DHRS12,MAPK13,DISP1,RPS23 |
| 1.327e-02 | -4.32 | response to glucocorticoid | biological process | GO:0051384 | 139 | 22 | 17256 | 1658 |
MSTN,PTPRU,ASS1,NTRK3,ABCC2,BMP6,DDIT4,FBXO32,BCHE,EIF4EBP1,CTSV,PAM,KLF9,ERRFI1,PCK2,AGL,SMYD3,SLIT2,ZFP36L2,ATP2B1,DUSP1,HEY1 |
| 1.327e-02 | -4.32 | negative regulation of neuron projection development | biological process | GO:0010977 | 139 | 22 | 17256 | 1658 |
EFNB2,DNM3,ID1,FGF13,DCC,RAPGEF2,LRP4,LRRK2,VIM,SEMA4F,PLK2,KIAA0319,ADCY6,PTPRS,INPP5F,SEMA3C,SPART,NRP1,GFI1,SEMA3A,ZNF365,SLIT2 |
| 1.328e-02 | -4.32 | PID | prosite domains | PS01179 | 31 | 8 | 12060 | 1278 |
NUMBL,GULP1,APBA1,APBA2,TBC1D1,TBC1D4,APBB1,NOS1AP |
| 1.328e-02 | -4.32 | SEMA | prosite domains | PS51004 | 31 | 8 | 12060 | 1278 |
SEMA6B,SEMA3C,MET,SEMA4F,SEMA3A,SEMA6A,SEMA6C,PLXNA2 |
| 1.328e-02 | -4.32 | GSE14415_NATURAL_TREG_VS_TCONV_UP | MSigDB lists | GSE14415_NATURAL_TREG_VS_TCONV_UP | 144 | 23 | 17377 | 1707 |
ARHGAP26,RUNX2,TTC39B,CNTNAP3,PTPN13,UBASH3B,FOXN3,SPATA6,SETBP1,ADAMTS6,SFXN3,IL18R1,FBXO32,ZBTB38,ICA1,TRIM34,TACC2,PPFIBP1,ZNF808,TOX,NEB,RASGRP1,FILIP1 |
| 1.328e-02 | -4.32 | GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_UP | 144 | 23 | 17377 | 1707 |
TNIK,KLHL3,RNF144A,NPM3,PLAG1,DCHS1,ATF7IP2,CR2,TTC28,BCL11A,TXNRD3,ID3,SEMA4F,PMAIP1,HPGD,MARCH3,PIK3C2B,SUSD4,MLLT3,RPS23,SCN3A,PKIA,SLC16A10 |
| 1.328e-02 | -4.32 | GO_REGULATION_OF_ACTIN_FILAMENT_LENGTH | MSigDB lists | GO_REGULATION_OF_ACTIN_FILAMENT_LENGTH | 144 | 23 | 17377 | 1707 |
SSH3,FER,EVL,DSTN,EPS8,PREX1,ADD2,PFN2,PPP1R9A,SPIRE1,FHOD3,BAIAP2,SCIN,GSN,PLEKHH2,MYADM,NCKAP1L,WIPF3,PRKCD,TMOD2,CTTN,NEB,SLIT2 |
| 1.328e-02 | -4.32 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_DN | 144 | 23 | 17377 | 1707 |
USP2,PLEKHA8,TCF24,FAM131C,JPH1,FEZ1,SORBS3,NTRK3,FAM198B,GAS6,FBXO36,TNKS1BP1,DKK1,EPB41L3,ENPP1,KAZN,ZNF521,FAM149A,PPP2R2B,SLCO4C1,BARX1,ZNF391,DENND5B |
| 1.329e-02 | -4.32 | GTGACTT,MIR-224 | MSigDB lists | GTGACTT,MIR-224 | 152 | 24 | 17377 | 1707 |
PDLIM7,RUNX2,NR4A1,FOXN3,PLAG1,MGAT4B,EFNA3,KCTD12,ENAH,NOTUM,CREB5,MBNL2,EYA4,MAP1B,RERE,TRIM9,ARHGAP21,ID3,RND3,GTSF1,TMEM117,APBA2,SEPT3,HMGCR |
| 1.330e-02 | -4.32 | regulation of ion transmembrane transport | biological process | GO:0034765 | 442 | 57 | 17256 | 1658 |
KCNV1,SCN5A,CACNG3,SCN8A,UBASH3B,HECW2,KCNC4,CACNB4,NEDD4,NOS1AP,LRRC55,KCNJ4,KCNAB1,KCNN2,TCAF2,SCN1B,CACNB2,EHD3,KCNS3,TRPC1,TSPAN13,PDE4D,TMEM37,SCN2A,HSPA2,KCNB2,SCN3A,ALG10B,DPP10,KCNIP3,GSTM2,KCNQ3,CACNA1E,KCNH5,ANK2,PTPN6,SHANK2,JPH1,FGF12,RYR2,GSTO1,KCND3,ATP1B1,AMIGO1,SNCA,IRS2,KCNK15,CXCL10,KCNG1,GEM,ATG5,PPARGC1A,TESC,ATP2B4,CACNA2D1,STOM,MEF2C |
| 1.331e-02 | -4.32 | chr8q12 | MSigDB lists | chr8q12 | 27 | 7 | 17377 | 1707 |
RPS20,TOX,FAM110B,ASPH,XKR4,PLAG1,SGK3 |
| 1.331e-02 | -4.32 | GO_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS | 27 | 7 | 17377 | 1707 |
SMAD3,DAB2IP,DACT1,WWTR1,SNAI2,RGS20,FZD1 |
| 1.331e-02 | -4.32 | BOYAULT_LIVER_CANCER_SUBCLASS_G2 | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G2 | 27 | 7 | 17377 | 1707 |
HIP1,SATB2,MEIS2,RRAS2,ALDOC,SLC2A6,FHOD3 |
| 1.331e-02 | -4.32 | BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_CLUSTER_UP | 27 | 7 | 17377 | 1707 |
OBSCN,GSTO1,SH3BGRL2,CLYBL,PLK2,STC2,NFIA |
| 1.331e-02 | -4.32 | GO_NEGATIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | 27 | 7 | 17377 | 1707 |
DNM3,ID1,DCC,PLK2,RAPGEF2,KIAA0319,BCL11A |
| 1.331e-02 | -4.32 | GO_NEURONAL_ACTION_POTENTIAL | MSigDB lists | GO_NEURONAL_ACTION_POTENTIAL | 27 | 7 | 17377 | 1707 |
SCN5A,KCNMB4,SCN2A,GRIK2,SCN8A,SCN3A,KCNMB3 |
| 1.331e-02 | -4.32 | TAKADA_GASTRIC_CANCER_COPY_NUMBER_DN | MSigDB lists | TAKADA_GASTRIC_CANCER_COPY_NUMBER_DN | 27 | 7 | 17377 | 1707 |
RGS16,CAB39L,FHIT,MDH1B,FNDC3A,SH3GL2,VLDLR |
| 1.332e-02 | -4.32 | upper_leg | COSMIC cancer mutations | upper_leg | 890 | 107 | 17385 | 1698 |
CCDC126,EPHA3,MYCBP2,ELOVL4,PDE1B,CFH,PTPN21,ASS1,PKP2,KIF21B,COL14A1,UBTD2,DOCK2,HMCN1,SLCO3A1,CPNE2,PPFIBP1,TRPC1,MDH1B,MET,PTPRE,FAM78B,SLIT2,KCNB2,DOCK8,SNAI2,FER,DCC,CYB5R2,ANK2,SHANK2,NFIA,ADCY1,TNS1,PYGO1,ATP10D,METAP1D,FGFR1,TMEM132B,SMAD3,PTPRJ,ENPP6,PTK7,CCBE1,ABI3,LAMB1,PTPRS,SEMA3C,INPP5F,KLHL31,STON2,HS6ST3,DYRK3,MRC2,STXBP5L,PTPRD,ZHX3,TSPAN15,ATP9A,ZNF25,GABRB2,EPS8,MCTP2,HERC5,CREB5,EPHB1,PPP2R3A,FUT9,ZIC5,FAM107B,LIMCH1,TOX,LOXL4,CHRM3,MED12L,RIMS2,NOS3,PARP9,VAV3,SYNPO2,KCNQ3,BTNL9,TBC1D8B,SPATA6,PTPN13,OGDHL,WWC1,PEX5L,SHISA2,PLCB1,KHDRBS2,PTPRC,GRIK4,PLEKHH2,TERT,ADAMTS3,FBN1,PLXDC2,C1orf21,CLMN,PTPRN2,MYOM2,PLD1,CRISPLD1,CACNA2D1,LARP1,ACSM3 |
| 1.334e-02 | -4.32 | CCCNNGGGAR_V$OLF1_01 | MSigDB lists | CCCNNGGGAR_V$OLF1_01 | 302 | 42 | 17377 | 1707 |
CHCHD7,PLAG1,COL18A1,SORBS3,FAM198B,APBA1,SEL1L3,DDR1,TNKS1BP1,CHD5,NEO1,MECOM,CA2,PPFIA2,PCBP4,STC2,CHRDL1,STEAP3,PACSIN1,TMEM132E,GLI1,DPYSL5,GCNT2,RHOQ,MEIS2,CYTH3,SLC25A28,ZDHHC14,SGK2,RNF44,GJC1,ICA1,GNAO1,PLXDC2,ABI3,C1orf21,PCGF2,ADRB1,GRIN2D,BMP4,TPM1,LPP |
| 1.334e-02 | -4.32 | proteoglycan metabolic process | biological process | GO:0006029 | 84 | 15 | 17256 | 1658 |
UST,CHSY3,HPSE,BMPR2,XYLT1,HS3ST5,DSEL,PXYLP1,CHSY1,HS3ST3B1,BCAN,SPOCK3,B4GALT7,GLCE,HS6ST3 |
| 1.334e-02 | -4.32 | regulation of anion transport | biological process | GO:0044070 | 84 | 15 | 17256 | 1658 |
IRS2,CA2,TCAF2,KMO,ATP8A1,MAP2K6,PRKCD,PRELID1,PRKG2,ABAT,STXBP1,TNFRSF11A,SYK,FGFR1,SNCA |
| 1.334e-02 | -4.32 | fatty acid derivative biosynthetic process | biological process | GO:1901570 | 84 | 15 | 17256 | 1658 |
PLA2G4A,FADS1,ACSL1,ALOX5AP,MGST3,ELOVL7,ELOVL3,BDH2,FASN,HACD1,HPGD,SCD,FAR2,SYK,PTGES |
| 1.334e-02 | -4.32 | calcium ion regulated exocytosis | biological process | GO:0017156 | 84 | 15 | 17256 | 1658 |
DOC2A,TRIM9,UNC13B,SYT12,RAPGEF4,CADPS2,SNAP25,SEPT5,SYT14,STXBP1,PCLO,TC2N,RIMS2,SCIN,SNPH |
| 1.335e-02 | -4.32 | V$NFY_Q6_01 | MSigDB lists | V$NFY_Q6_01 | 251 | 36 | 17377 | 1707 |
PPP4R4,CELSR3,DHCR24,CADM2,SCD,CHAC1,NKX6-1,ZNF362,KCNN2,CDC14B,RPS6KL1,TMEM143,KLF9,SPRY2,ZNF385A,POU3F3,PDGFRB,DPYSL5,FADS1,PTCH2,GCA,MICAL2,SESN2,KLHL4,NUAK2,ATOH1,HERPUD1,NT5DC2,ZNF711,ABI3,WDR19,DLG2,ZBTB20,HOXB9,SIX2,DOCK9 |
| 1.335e-02 | -4.32 | specification of symmetry | biological process | GO:0009799 | 123 | 20 | 17256 | 1658 |
MICAL2,NBL1,ACVR1,NKX3-2,ACVR2B,OVOL2,SMAD3,ARMC4,SETDB2,LRRC6,DYNC2LI1,TBC1D32,ACVR2A,DYNC2H1,BMP4,DISP1,DNAH5,PCSK6,MEF2C,PCSK5 |
| 1.338e-02 | -4.31 | CRMPs in Sema3A signaling | REACTOME pathways | R-HSA-399956 | 16 | 5 | 10287 | 971 |
DPYSL5,NRP1,SEMA3A,FES,PLXNA2 |
| 1.338e-02 | -4.31 | Sema3A PAK dependent Axon repulsion | REACTOME pathways | R-HSA-399954 | 16 | 5 | 10287 | 971 |
PAK1,NRP1,SEMA3A,FES,PLXNA2 |
| 1.342e-02 | -4.31 | Arrhythmogenic Right Ventricular Cardiomyopathy | WikiPathways | WP2118 | 76 | 15 | 5312 | 569 |
TCF7L1,ITGB7,CACNG3,CACNB2,ITGA6,DSG2,ITGA2,ITGB3,RYR2,PKP2,CDH2,DSP,CACNB4,CACNA2D1,CTNNA2 |
| 1.348e-02 | -4.31 | sulfur compound binding | molecular function | GO:1901681 | 236 | 34 | 17224 | 1680 |
TENM1,FN1,CFH,SELL,CBS,TGFBR3,SOAT2,ABI3BP,COL25A1,HS3ST5,GSTM3,PCOLCE2,SLIT2,PCSK6,FGFR4,GSTM2,MSTN,WISP3,GSTM4,OGDHL,RYR2,GPC6,FGFR1,TPK1,CXCL10,ENPP1,FBN1,ADAMTS3,THBS4,ITGA2,PTPRS,BMP4,NRP1,PTGES |
| 1.349e-02 | -4.31 | response to carbohydrate | biological process | GO:0009743 | 172 | 26 | 17256 | 1658 |
PRKAA2,SESN2,COL6A2,ACVR1C,PFKFB2,CALCRL,GAS6,ACVR2B,RACK1,ILDR2,GPLD1,NKX6-1,RAB11FIP5,IRS2,UNC13B,IGF1R,MAP2K6,CTSV,ERN1,XBP1,ITGA2,SREBF1,PTPRN2,MAPK13,PPARGC1A,PCK2 |
| 1.349e-02 | -4.31 | GO_STEROID_METABOLIC_PROCESS | MSigDB lists | GO_STEROID_METABOLIC_PROCESS | 226 | 33 | 17377 | 1707 |
PRKAA2,TFCP2L1,MVK,EBPL,SLC27A2,MVD,CYB5R2,VLDLR,LDLR,DHCR24,CYP4V2,CEBPA,STAT5B,NPC2,PLEKHA1,LEPR,CYP51A1,IDI1,HMGCS1,SOAT2,INSIG1,MSMO1,SRD5A3,FABP6,OSBPL5,SREBF1,SQLE,TNFSF4,PPARGC1A,DHCR7,ABCG1,CYP1B1,HMGCR |
| 1.352e-02 | -4.30 | TMEM185A (transmembrane protein 185A) | protein interactions | 84548 | 59 | 12 | 17029 | 1718 |
CPNE2,GPRIN1,GNB4,C1orf21,RAP2A,EEPD1,NCAM1,PRKCA,UBTD2,NCS1,CACNA2D1,SMPDL3B |
| 1.352e-02 | -4.30 | Z disc | cellular component | GO:0030018 | 125 | 20 | 18223 | 1724 |
PAK1,SCN5A,SYNPO2,SCN8A,ANK2,JPH1,FHL2,RYR2,OBSCN,PALLD,NOS1AP,FHOD3,BAG3,FBXO32,KCNN2,PDLIM3,AHNAK2,MYOM2,NEB,ATP2B4 |
| 1.358e-02 | -4.30 | FACIT collagen trimer | cellular component | GO:0005593 | 6 | 3 | 18223 | 1724 |
COL9A3,COL14A1,COL9A2 |
| 1.358e-02 | -4.30 | collagen type IV trimer | cellular component | GO:0005587 | 6 | 3 | 18223 | 1724 |
COL4A5,COL4A3,COL4A4 |
| 1.358e-02 | -4.30 | GO_GLAND_DEVELOPMENT | MSigDB lists | GO_GLAND_DEVELOPMENT | 389 | 52 | 17377 | 1707 |
BCL11B,TFCP2L1,PLAG1,GATA3,ASS1,CEBPA,STAT5B,DDR1,CACNB4,HMGCS1,ASNS,TGFBR3,GATA2,TNFRSF11A,IGSF3,GLI1,NKX2-1,MSX1,CSN2,KDM5B,WLS,ARID5B,FASN,MAFB,AK4,WNT11,FGFR1,MGMT,CEBPB,SMAD3,IRS2,NRG3,CSF1,ATP7B,XBP1,ITGA2,PAM,HK2,SEMA3C,HGF,HOXD13,DBP,OXTR,BMPR1A,BMP4,NRP1,HOXB9,NKX2-8,SEMA3A,COBL,FOXA1,BTRC |
| 1.361e-02 | -4.30 | PPM1H (protein phosphatase, Mg2+/Mn2+ dependent 1H) | protein interactions | 57460 | 95 | 17 | 17029 | 1718 |
CGN,PHLDB2,SCAMP1,RASAL2,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,SLC6A15,TANC2,OSBPL6,LARP1,GAB2 |
| 1.362e-02 | -4.30 | extrinsic component of cytoplasmic side of plasma membrane | cellular component | GO:0031234 | 109 | 18 | 18223 | 1724 |
TNK2,FER,GNG12,FARP1,CYTH3,FERMT2,HIP1,SNAP25,RGS7,FRK,SNX9,GNAI1,FGR,KCNAB1,GNAO1,ERRFI1,SYK,FES |
| 1.364e-02 | -4.29 | GSE28237_EARLY_VS_LATE_GC_BCELL_UP | MSigDB lists | GSE28237_EARLY_VS_LATE_GC_BCELL_UP | 193 | 29 | 17377 | 1707 |
FRMPD3,VNN2,MYO1D,FLVCR2,ARL15,FZD8,BIK,TTC30A,GABRR2,FAM198B,HTR7,RNF180,IFT81,CPNE2,FAT4,SLC30A4,SLC22A18,PDE10A,ATP7B,RASD2,PLEKHG1,RAB26,SCARF2,ZNF474,BMPR1A,FNBP1L,MMP16,HS6ST3,IGFBP3 |
| 1.364e-02 | -4.29 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | 193 | 29 | 17377 | 1707 |
EFNB2,QSOX1,USP2,PDE1B,PLEKHA5,CD276,SPATA6,RAPGEF4,SDC3,NTRK3,IKZF2,SLCO3A1,BMP6,STK24,MMP15,MCOLN2,RPS6KA2,RPL12,CA2,SLC7A11,RALGPS2,ITGB3,MAP7,SVIL,ZBTB20,PLTP,ABCG1,TPT1,PHC1 |
| 1.364e-02 | -4.29 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_UP | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_UP | 193 | 29 | 17377 | 1707 |
ITGB7,EIF4E3,LGALS3,IGFBP6,FHL2,GATA3,COBLL1,VIM,PRDM1,CHSY1,DOCK5,CD7,SLCO3A1,IL18R1,PRRG4,SMPDL3B,NEDD4,TXNDC5,GALNT3,ENTPD1,IKZF3,MYADM,FRY,PIK3AP1,ITGB3,SGK1,TMEM37,ARL4D,FES |
| 1.364e-02 | -4.29 | GSE17721_LPS_VS_CPG_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDC_UP | 193 | 29 | 17377 | 1707 |
CXCR5,MXI1,GCNT2,ACSL1,RUNX2,IL15,AASS,REL,PLEKHA5,CALCRL,RAB38,ATP1B1,SAV1,FNDC3A,TNKS1BP1,DYNC1I1,F3,DYRK1B,TLR3,GYPC,KPNA3,PMEPA1,LAPTM4B,TUFT1,PROS1,IL1RAP,ZFP36L2,LARP1,PARP9 |
| 1.364e-02 | -4.29 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_UP | 193 | 29 | 17377 | 1707 |
QSOX1,BTC,USP2,COL6A2,CFH,RECK,ATP9A,PLEKHA5,SPATA6,CYTH3,RAPGEF4,PPFIBP2,WNT11,IKZF2,F3,MCOLN2,RPL12,RPS6KA2,CA2,SEMA4F,RALGPS2,AKAP7,MAP2K6,OSBPL5,BCL6,MAP7,ZBTB20,HGF,ABCG1 |
| 1.364e-02 | -4.29 | GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN | MSigDB lists | GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN | 193 | 29 | 17377 | 1707 |
CXCR5,RHOQ,ALDH2,PTPN6,LRMP,NFE2L1,CR2,KCTD12,C1R,RASD1,SCD,CD40,ZDHHC14,SNX9,NEDD4,EBF1,MCOLN2,SIPA1L2,CD37,ARHGAP21,MYADM,CA2,RALGPS2,PRKCD,XBP1,OSBPL5,MARCKS,SYK,MEF2C |
| 1.368e-02 | -4.29 | V$ATF4_Q2 | MSigDB lists | V$ATF4_Q2 | 243 | 35 | 17377 | 1707 |
PHACTR3,SV2B,SORBS1,ID1,NDRG2,CHAC1,PRR7,KCNN2,CDC14B,TMEM86A,SGK1,PDE4D,SYNGR3,ENO1,DUSP1,NKX2-1,PAK1,USP2,PNRC1,PTPRU,PRICKLE1,PNMA6A,RNF44,MBNL2,ZNF711,ICA1,ALDOA,MPP2,MAOA,ZBTB20,GEM,ATG5,PKIA,DIRC2,LPP |
| 1.371e-02 | -4.29 | carbohydrate derivative binding | molecular function | GO:0097367 | 2160 | 240 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,JCHAIN,BCAN,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,RPS6KA2,TGFBR3,ABI3BP,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PCOLCE2,TLR4,SLIT2,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,CEMIP2,ACVR1C,WISP3,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GPC6,GNAI1,DYRK1B,AK1,ENPP1,HPSE,PLK2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,NRP1,DNHD1,SPOCK3,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,FN1,RHOBTB1,BVES,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,NOS3,PAK1,FGFR4,PODXL2,RHOQ,PNP,MSTN,MYO10,SLC27A2,PLEKHA8,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,ADAMTS3,PKN3,THBS4,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,CFH,RHOD,MYO1B,CHUK,MAPK4,NTRK3,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,COL25A1,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,CXCL10,POPDC3,PRKCB,GBP1,PTK7,ITGA2,MAP3K21,PTPRS,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TENM1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,SELL,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PCSK6,PARP9,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,FBN1,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,BMP4,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 |
| 1.377e-02 | -4.29 | NAD biosynthesis II (from tryptophan) | BIOCYC pathways | META_NADSYN-PWY | 9 | 4 | 902 | 105 |
NMNAT3,TDO2,KMO,QPRT |
| 1.378e-02 | -4.28 | FBXL13 (F-box and leucine rich repeat protein 13) | protein interactions | 222235 | 39 | 9 | 17029 | 1718 |
NKX6-1,LONRF1,CGN,AASS,VWDE,RAPGEF4,CIART,NEB,CYP26A1 |
| 1.378e-02 | -4.28 | LONRF1 (LON peptidase N-terminal domain and ring finger 1) | protein interactions | 91694 | 39 | 9 | 17029 | 1718 |
LONRF1,TRIM9,USP2,NR4A1,EFHC2,UCHL3,IKZF2,SPRY2,SFN |
| 1.378e-02 | -4.28 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM1 | 218 | 32 | 17377 | 1707 |
ANO10,AVPI1,KLHL13,PTPN21,COL4A5,PRKCA,PHGDH,DDIT4,SCN1B,MARVELD2,CTTN,IQGAP3,PTPRE,PDLIM7,TNK2,ATF4,COL4A3,SFXN4,C3orf52,AIG1,SATB2,GPC6,PYCR1,SNCA,TRIB3,RPL12,SH3GL2,MYADM,RND3,RAI14,TESC,PSPH |
| 1.379e-02 | -4.28 | TyrKc | smart domains | SM00219 | 80 | 16 | 9493 | 1056 |
EPHA3,FGFR4,TYRO3,FER,TNK2,NTRK3,EPHB1,DDR1,FRK,FGFR1,FGR,IGF1R,MET,SYK,FES,PDGFRB |
| 1.379e-02 | -4.28 | GO_EMBRYONIC_ORGAN_MORPHOGENESIS | MSigDB lists | GO_EMBRYONIC_ORGAN_MORPHOGENESIS | 277 | 39 | 17377 | 1707 |
ACVR1,RUNX2,CELSR1,OTX1,GATA3,OVOL2,EFEMP1,SETDB2,PDZD7,GATA2,DLX6,TFAP2A,SPRY2,GLI1,MICAL2,MSX1,NKX3-2,MAFB,YAP1,RYR2,WNT11,SATB2,ATOH1,HOXA1,FGFR1,ZIC1,SMAD3,INSIG1,FBN1,PTK7,WDR19,PCGF2,BMP4,DLX2,NRP1,SHOX2,MMP16,SIX2,MEF2C |
| 1.380e-02 | -4.28 | AMIT_EGF_RESPONSE_480_MCF10A | MSigDB lists | AMIT_EGF_RESPONSE_480_MCF10A | 40 | 9 | 17377 | 1707 |
VEGFC,TRIB3,POPDC3,PMAIP1,SH2D2A,ITGA2,SMTN,GRB10,PHLDA2 |
| 1.380e-02 | -4.28 | NABA_BASEMENT_MEMBRANES | MSigDB lists | NABA_BASEMENT_MEMBRANES | 40 | 9 | 17377 | 1707 |
LAMC3,COL18A1,COL4A5,COL6A2,COL4A3,COL4A4,NTNG1,HMCN1,LAMB1 |
| 1.381e-02 | -4.28 | response to hormone | biological process | GO:0009725 | 887 | 105 | 17256 | 1658 |
SORBS1,ACSL1,TRIM16,RBFOX2,ASS1,NTRK3,STAT5B,PLPP1,FBXO32,TGFBR3,ASNS,TSHR,SLIT2,PRKACB,PDGFRB,NKX2-1,FER,SESN2,PTPRU,NR6A1,ACVR1C,ADCY1,YAP1,PRKAR2B,ABCC2,GNAI1,IRS2,ENPP1,EIF4EBP1,GNB4,ITGA2,RGS10,PAM,HPGD,OXTR,TNFSF4,PPARGC1A,NR3C2,PSPH,CGB2,HEY1,MEF2C,PRKAA2,GNG12,LATS2,INPPL1,ROBO2,DHCR24,ATP6V1E2,BMP6,NEDD4,DDIT4,NKX6-1,FOXP2,HMGCS1,EEF2,IGF1R,CA2,BCHE,DSG2,PRKCD,STC2,GHR,SREBF1,LRP6,ADCY6,GRIP1,KLF9,ERRFI1,PCK2,AGL,STXBP1,ZFP36L2,CHRM3,ATP2B1,DUSP1,NOS3,PAK1,RHOQ,PXN,MSTN,HNF4G,NR4A1,ESRRG,FHL2,MARS,PLCB1,LEPR,BAIAP2,CPEB1,GPLD1,MMP15,TRIB3,PMEPA1,FBN1,CTSV,XBP1,RAB31,HOXD13,BMP4,TBC1D4,SMYD3,FOXA1,ABCG1,ATP1A3 |
| 1.382e-02 | -4.28 | GO_SH3_DOMAIN_BINDING | MSigDB lists | GO_SH3_DOMAIN_BINDING | 113 | 19 | 17377 | 1707 |
INPPL1,SH3BP2,PLSCR4,EVL,DOCK1,SH2D2A,PTPN6,SHANK2,DNAJC6,ENAH,DOCK3,SKAP1,KHDRBS2,WIPF3,DAB2IP,AFAP1L2,SH3BGRL2,ERRFI1,CTTNBP2 |
| 1.383e-02 | -4.28 | cerebellum development | biological process | GO:0021549 | 92 | 16 | 17256 | 1658 |
PAK1,SCN5A,FZD4,OPHN1,NLGN4X,ABAT,AARS,CBLN1,RERE,FOXP2,LRP6,PTPRS,PPARGC1A,ZNF365,CNTN1,GLI1 |
| 1.383e-02 | -4.28 | heart process | biological process | GO:0003015 | 92 | 16 | 17256 | 1658 |
SCN5A,ANK2,FGF12,RYR2,PKP2,KCND3,ATP1B1,GJC1,KCNN2,SCN1B,MAP2K6,CACNB2,PDE4D,TPM1,ATG5,CACNA2D1 |
| 1.383e-02 | -4.28 | columnar/cuboidal epithelial cell differentiation | biological process | GO:0002065 | 92 | 16 | 17256 | 1658 |
B9D1,ENAM,NKX3-2,MCOLN3,WNT11,PRDM1,ATOH1,SAV1,BMP6,FGFR1,NKX6-1,PDZD7,KLF5,BMP4,CDH2,FOXA1 |
| 1.384e-02 | -4.28 | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | 185 | 28 | 17377 | 1707 |
RHOQ,ACSL1,BLVRB,LRMP,BNIP3L,SETBP1,PRKAR2B,WDFY4,TMEM170B,MLC1,BMP6,RTN1,CEBPB,GBGT1,EPB41L3,PRCP,PLXDC2,SLC2A6,PRKCD,KIAA0513,SLC22A15,RNF130,PTPRE,TLR4,SYK,FMNL2,ZNF385A,TBC1D8 |
| 1.384e-02 | -4.28 | GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 185 | 28 | 17377 | 1707 |
ALDH2,ABCC4,VAMP8,NFE2L1,ASS1,NRN1,NPC2,CHAC1,BATF,ARRDC4,RBM11,SNX9,TBC1D30,HOPX,GPR15,SEMA4F,IKZF5,CHRNA5,PMEPA1,CLDN12,INPP4B,TUFT1,PROS1,CERS4,TESC,CSRP2,CRYL1,RRAGD |
| 1.384e-02 | -4.28 | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 185 | 28 | 17377 | 1707 |
MN1,C2orf88,ZNF516,RUSC2,CYB5R2,MYO1B,RNF24,SLC1A3,SAV1,ZNF219,SEL1L3,SATB1,DOCK2,NCS1,MGMT,CPNE2,MYADM,PMEPA1,WFS1,MCF2L,CNNM2,TSPAN13,DAB2IP,SH3PXD2B,STXBP1,PTPRE,BTRC,CYP1B1 |
| 1.384e-02 | -4.28 | GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP | MSigDB lists | GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP | 185 | 28 | 17377 | 1707 |
PPP4R4,SKAP2,UBASH3B,PTPN6,MAFB,HBE1,TTC22,COTL1,SEZ6L2,C4orf19,PTPRC,ATXN7L1,CXCL10,PTPRJ,EOMES,PDZD8,PIK3AP1,DIRAS1,IPCEF1,POU2F2,TBC1D9,DENND1C,GFI1,PTPRE,TNFRSF11A,FMNL2,GATM,FES |
| 1.384e-02 | -4.28 | GSE17721_0.5H_VS_4H_CPG_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_CPG_BMDC_DN | 185 | 28 | 17377 | 1707 |
VNN2,GCA,SYNPO2,ENO2,IL15,SLC27A2,TBC1D1,REL,PPFIBP2,CALCRL,KIF5C,IGF2BP2,SATB2,TJP1,FNDC3A,CCNJ,ISG20,MAPKAPK2,TTC1,RTN1,SLC39A14,RPS6KA2,CSF1,GFI1,STXBP1,PTGES,PDGFRB,RRAGD |
| 1.384e-02 | -4.28 | GSE27786_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NKCELL_DN | 185 | 28 | 17377 | 1707 |
EIF4E3,ALDH2,MPP1,LRP4,ATOX1,SPATA13,SCD,P2RY1,DSP,SNX9,SLC46A3,MBNL2,BAG3,PTPRJ,HPSE,AKAP7,MARVELD2,FAM168A,TMEM86A,RAP2A,HGF,KLF9,ALPK1,GEM,RNF157,NEUROG2,HSPA2,CSRP2 |
| 1.384e-02 | -4.28 | GSE14350_IL2RB_KO_VS_WT_TEFF_UP | MSigDB lists | GSE14350_IL2RB_KO_VS_WT_TEFF_UP | 185 | 28 | 17377 | 1707 |
ERGIC1,BMPR2,GSTM4,FOXN3,OTX1,BATF,RPL13A,RERE,SCIN,NKX6-1,MCOLN2,RAB11FIP5,ID3,KCNMB4,TMEM154,BACH2,IGF1R,SEMA4F,PLAGL1,NCOA7,SH3BP4,DUSP19,PTPRS,CCDC122,TNFSF4,MAST4,RNF122,KIAA1211 |
| 1.384e-02 | -4.28 | MEK_UP.V1_DN | MSigDB lists | MEK_UP.V1_DN | 185 | 28 | 17377 | 1707 |
COL9A3,MOCOS,GDAP1,SEC24D,ASS1,KIF5C,MAFB,SATB2,ATF3,PRKAR2B,F12,HERC6,QPRT,CHN1,ABLIM1,SYCP2,IGF1R,MYC,INPP4B,MPDZ,INPP5F,TTC39A,SNX10,AGL,GFRA1,PSPH,RASGRP1,SMPDL3A |
| 1.384e-02 | -4.28 | GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 185 | 28 | 17377 | 1707 |
VEGFC,RIN2,GNG12,DSTN,EFNA3,FASN,MAFB,C1R,CEBPA,RARRES2,RAC3,BATF3,CD53,SNCA,ARHGEF10L,SLC35F1,PTPRJ,ALDOA,LRP6,EGFL7,STEAP3,LOXL4,ATG5,VWA5A,APBA2,TSHR,SNX10,IGSF3 |
| 1.384e-02 | -4.28 | GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_UP | MSigDB lists | GSE22229_UNTREATED_VS_IMMUNOSUPP_THERAPY_RENAL_TRANSPLANT_PATIENT_PBMC_UP | 185 | 28 | 17377 | 1707 |
PLSCR4,SORBS1,SMAD9,KDM5B,CRIM1,CAP2,AGPAT4,PRKCQ,LHPP,F12,DOCK5,FAM110B,QPRT,TXNRD3,ISG20,BCL11A,KIAA1958,GNB4,MPPED2,MAP7,MARCH3,TSPAN13,NAP1L3,DLX2,CTTN,STXBP1,OSBPL6,GPR161 |
| 1.391e-02 | -4.28 | DH_2 | prosite domains | PS50010 | 70 | 14 | 12060 | 1278 |
ARHGEF10L,VAV3,ARHGEF28,FARP1,ARHGEF11,RASGRF2,MCF2L2,MCF2L,PREX1,SPATA13,PLEKHG1,OBSCN,TIAM2,ARHGEF26 |
| 1.401e-02 | -4.27 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | 177 | 27 | 17377 | 1707 |
MOB1B,DBN1,VNN2,MPP1,ATP8A1,DHCR24,MCTP2,LRRCC1,FASN,SELL,CHRNA6,CHSY1,SLC12A6,PALLD,NDFIP2,ILDR2,CENPV,BATF3,SLC39A14,GSTO2,CLDN12,SLC7A5,SQLE,CTTN,GEM,VWA5A,GFI1 |
| 1.401e-02 | -4.27 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP | 177 | 27 | 17377 | 1707 |
MXI1,ID1,TUBA1A,PNRC1,GSTM4,ARID5B,EPS8,DEPTOR,BNIP3L,CALCRL,IL13RA1,NTRK3,PALLD,DDR1,QPRT,HOMER3,GSN,HLF,CA2,SLC7A11,PPFIBP1,ACTA2,ZBTB20,TOX,TNFSF4,FAR2,FNBP1L |
| 1.401e-02 | -4.27 | GSE2585_THYMIC_MACROPHAGE_VS_MTEC_DN | MSigDB lists | GSE2585_THYMIC_MACROPHAGE_VS_MTEC_DN | 177 | 27 | 17377 | 1707 |
DMXL2,GARS,PXN,FLVCR2,ESRP1,ARID5B,MSR1,SETBP1,RNF24,EFHC1,AARS,DOK5,DDIT4,ISG20,GALNT3,ENTPD1,SLC7A11,PMEPA1,PRKCB,FRAS1,KCNS3,INHBE,NBEA,BNIP3,HK1,NEB,ATP2B4 |
| 1.401e-02 | -4.27 | GSE3982_BASOPHIL_VS_NKCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_NKCELL_UP | 177 | 27 | 17377 | 1707 |
ACVR1,KDM5B,RUSC2,PTPN6,BEGAIN,GSTO1,STAT5B,ATP10D,CTNNA2,RERE,CEBPB,SFXN1,CDR2L,TM9SF2,BACE2,CSF1,KIAA0319,RAB31,KIAA0513,SVIL,GRB10,WWC2,FNBP1L,KLHL29,LRP12,RRAGD,TPT1 |
| 1.404e-02 | -4.27 | GO_POSITIVE_REGULATION_OF_AXONOGENESIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_AXONOGENESIS | 68 | 13 | 17377 | 1707 |
RND2,BDNF,DISC1,FN1,ROBO2,BMPR2,NTRK3,AMIGO1,NRP1,SHOX2,SLIT2,MAP1B,BCL11A |
| 1.404e-02 | -4.27 | BOYLAN_MULTIPLE_MYELOMA_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_DN | 68 | 13 | 17377 | 1707 |
ARHGAP26,GSN,ARHGAP21,ARAP2,EHHADH,SLC37A1,PSTPIP2,MARCKS,ATP11A,IPCEF1,DENND1C,CMPK2,LIFR |
| 1.404e-02 | -4.27 | Homocysteine Degradation | SMPDB pathways | SMP00455 | 2 | 2 | 992 | 118 |
CBS,CTH |
| 1.404e-02 | -4.27 | Homocystinuria- cystathionine beta-synthase deficiency | SMPDB pathways | SMP00515 | 2 | 2 | 992 | 118 |
CBS,CTH |
| 1.404e-02 | -4.27 | Gamma-cystathionase deficiency (CTH) | SMPDB pathways | SMP00514 | 2 | 2 | 992 | 118 |
CBS,CTH |
| 1.405e-02 | -4.27 | positive regulation of biosynthetic process | biological process | GO:0009891 | 1831 | 203 | 17256 | 1658 |
THOC5,ACVR1,LGR4,TRIM16,DNAJC3,LDLR,ASS1,LILRB1,GATA3,NPM1,CTBP2,STAT5B,CEBPA,ABHD6,IKZF2,NOS1AP,TRPS1,SKI,EPCAM,ARHGEF10L,EOMES,GRHL1,ETV1,TLR4,TSHR,FANK1,ENO1,POU3F3,PDGFRB,NKX2-1,SESN2,MEIS2,ATF4,SMAD9,NR6A1,LRRK2,NFIA,NFE2L1,YAP1,MEF2B,BATF,AHRR,DYRK1B,HLF,INSIG1,ADRB1,NCOA7,TNFRSF1A,DLX2,PPARGC1A,MLLT3,MEF2C,BCL11B,PRKAA2,RUNX2,ITGA6,FBXO4,ZIC2,MECOM,ZBTB38,EEF2,GATA2,MYC,SREBF1,EBF4,LRP6,GRIP1,GLIS1,PRR16,BARX1,CAND2,GPR161,CEBPD,NOS3,FGFR4,RPL26,RAX,RHOQ,MSTN,STAT4,FHL2,WWC1,MAFB,SMARCD3,TAF4B,PLCB1,MAPKAPK2,PLAGL1,HEYL,HOXD13,NKX2-8,SMYD3,TESC,SIX2,CREB3L2,PRKN,SORBS1,ZNF516,IL15,OTX1,CHUK,LPIN3,TLR3,STARD4,ACVR2A,DAB2IP,POU2F2,MET,GLI1,ALG10B,FZD1,PFKFB2,FZD4,SOX21,VIM,PRKCQ,WNT11,SATB2,ATF3,PXYLP1,ATOH1,PYGO1,CD40,FGFR1,SNCA,IRS2,ZNF711,SMAD3,CXCL10,IKZF3,PEMT,WWTR1,ITGA2,SOHLH2,HGF,KLF5,BMPR1A,DBP,HOXB9,HEY1,BMPR2,CKAP2,ARHGEF11,FZD8,REL,CD276,PLAG1,APBB1,P2RY1,CREB5,OVOL2,ZNF219,BMP6,NKX6-1,KDM7A,BHLHA15,PRKCD,GTF2F2,TFAP2A,AFAP1L2,YBX3,MYO6,SMAD6,SYK,SLC45A3,MED12L,PARP9,PFKFB4,MICAL2,SLC40A1,MSX1,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,MARS,AGAP2,RACK1,ZFPM2,GUCY1A2,SKAP1,TLR6,HOXA1,ZIC1,GPLD1,RERE,EBF1,CEBPB,NSD1,DDAH1,TERT,MAP2K6,XBP1,MYRF,PAX9,BMP4,SHOX2,DDIT3,LARP1,BTRC,FOXA1,ABCG1 |
| 1.406e-02 | -4.26 | V$SRF_Q4 | MSigDB lists | V$SRF_Q4 | 210 | 31 | 17377 | 1707 |
MSX1,MEIS2,KLHL3,NR4A1,NPM3,DSTN,MYO1B,STAT5B,TMEM47,GRK6,FGF17,ASPH,PPP2R3A,RERE,MAPKAPK2,FOXP2,MAP1A,MAP2K6,RASD2,EMILIN2,SVIL,SGK1,SHF,DLG2,SERPINH1,TPM1,MID1,TMEM56,RAB30,GAB2,LPP |
| 1.408e-02 | -4.26 | GO_EXTRACELLULAR_MATRIX_COMPONENT | MSigDB lists | GO_EXTRACELLULAR_MATRIX_COMPONENT | 121 | 20 | 17377 | 1707 |
COL4A3,FN1,THSD4,COL4A4,ITGA6,LAMC3,COL18A1,COL4A5,GSTO1,SLC1A3,COL14A1,HMCN1,COL27A1,SNCA,EFEMP1,FBN1,FRAS1,THBS4,MATN2,LAMB1 |
| 1.408e-02 | -4.26 | V$PBX1_02 | MSigDB lists | V$PBX1_02 | 121 | 20 | 17377 | 1707 |
PHACTR3,MEIS2,SLITRK2,COL4A3,FGF13,COL4A4,CYB5R2,CCNG1,MGAT5B,ZFPM2,EML1,ZIC1,NSD1,GRIK4,GNAO1,HOXD13,KLF9,C15orf41,RIMS2,MEF2C |
| 1.414e-02 | -4.26 | regulation of actin filament length | biological process | GO:0030832 | 181 | 27 | 17256 | 1658 |
TENM1,FER,SSH3,EVL,TMSB15A,DSTN,EPS8,PREX1,ADD2,PFN2,RAC3,PPP1R9A,BAIAP2,SPIRE1,FHOD3,SCIN,GSN,PLEKHH2,MYADM,WIPF3,NCKAP1L,PRKCD,ARHGAP28,TMOD2,CTTN,NEB,SLIT2 |
| 1.414e-02 | -4.26 | ovulation cycle process | biological process | GO:0022602 | 41 | 9 | 17256 | 1658 |
ROBO2,MSTN,FZD4,MAP2K6,PAM,STAT5B,PLEKHA1,SLIT2,NOS3 |
| 1.414e-02 | -4.26 | L-alpha-amino acid transmembrane transport | biological process | GO:1902475 | 41 | 9 | 17256 | 1658 |
SLC7A1,SLC3A2,SLC7A11,SLC7A5,SLC36A4,SLC1A3,SLC7A2,SLC1A5,SLC43A1 |
| 1.414e-02 | -4.26 | response to dexamethasone | biological process | GO:0071548 | 41 | 9 | 17256 | 1658 |
ASS1,ABCC2,FBXO32,PCK2,ERRFI1,MSTN,EIF4EBP1,SMYD3,DDIT4 |
| 1.415e-02 | -4.26 | CASK (calcium/calmodulin dependent serine protein kinase) | protein interactions | 8573 | 88 | 16 | 17029 | 1718 |
PRKN,ID1,GRIK2,EPS8,BNIP3L,SDC3,MARS,APBA1,NRXN1,ARHGEF26,ABLIM1,KCNJ4,EEF2,PLK2,LIN7A,ATP2B4 |
| 1.416e-02 | -4.26 | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | 169 | 26 | 17377 | 1707 |
MAN2B2,VNN2,ITGB7,EVL,EIF4E3,ARHGEF11,PTPN13,UBASH3B,GALNT12,ITGA6,EFHC2,RNF125,ARHGAP32,ZDHHC14,FAM13A,ASPH,GPR160,FAM168A,SLC10A7,BMP1,TSC22D1,ZBTB20,FHIT,FKBP14,PNMA2,DUSP1 |
| 1.416e-02 | -4.26 | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | 169 | 26 | 17377 | 1707 |
ACSL1,DYRK3,REL,RAPGEF2,STAT4,GJB2,ELOVL7,HECW2,SAV1,SNX9,PHLDA2,DDIT4,F3,OTUD1,TIFA,PIK3AP1,PMAIP1,MFSD2A,STARD4,SLC7A5,PLD1,GEM,ERRFI1,ATP2B1,DUSP1,LAMP3 |
| 1.416e-02 | -4.26 | GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_UP | MSigDB lists | GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_UP | 169 | 26 | 17377 | 1707 |
CREB3L2,PFKFB4,TFCP2L1,VNN2,FN1,ALOX5AP,PTPRU,BACE1,XYLT1,NPC2,SEL1L3,ENTPD1,FGR,MYADM,PRKCB,WFS1,ITGB3,C1orf53,EEPD1,FHIT,PCK2,SLC45A3,PGBD5,PHC1,CES3,ALG10B |
| 1.417e-02 | -4.26 | metencephalon development | biological process | GO:0022037 | 100 | 17 | 17256 | 1658 |
PAK1,SCN5A,FZD4,OTX1,OPHN1,NLGN4X,ABAT,AARS,CBLN1,RERE,FOXP2,LRP6,PTPRS,PPARGC1A,ZNF365,CNTN1,GLI1 |
| 1.417e-02 | -4.26 | glycosylceramide biosynthetic process | biological process | GO:0046476 | 6 | 3 | 17256 | 1658 |
UGT8,B3GALT1,B3GALT2 |
| 1.417e-02 | -4.26 | positive regulation of megakaryocyte differentiation | biological process | GO:0045654 | 6 | 3 | 17256 | 1658 |
GATA2,TESC,SCIN |
| 1.417e-02 | -4.26 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication | biological process | GO:0086073 | 6 | 3 | 17256 | 1658 |
PKP2,DSP,DSG2 |
| 1.417e-02 | -4.26 | heparan sulfate proteoglycan biosynthetic process, enzymatic modification | biological process | GO:0015015 | 6 | 3 | 17256 | 1658 |
HS3ST3B1,HS6ST3,HS3ST5 |
| 1.417e-02 | -4.26 | dense core granule exocytosis | biological process | GO:1990504 | 6 | 3 | 17256 | 1658 |
CADPS2,UNC13B,STXBP1 |
| 1.417e-02 | -4.26 | protein transport along microtubule | biological process | GO:0098840 | 6 | 3 | 17256 | 1658 |
KIF5C,DLG2,MAP1A |
| 1.417e-02 | -4.26 | microtubule-based protein transport | biological process | GO:0099118 | 6 | 3 | 17256 | 1658 |
KIF5C,DLG2,MAP1A |
| 1.417e-02 | -4.26 | L-serine biosynthetic process | biological process | GO:0006564 | 6 | 3 | 17256 | 1658 |
SERINC5,PHGDH,PSPH |
| 1.417e-02 | -4.26 | regulation of fibroblast growth factor production | biological process | GO:0090270 | 6 | 3 | 17256 | 1658 |
WNT11,FGFR1,HEG1 |
| 1.417e-02 | -4.26 | negative regulation of mononuclear cell migration | biological process | GO:0071676 | 6 | 3 | 17256 | 1658 |
NBL1,PLCB1,SLIT2 |
| 1.417e-02 | -4.26 | muscular septum morphogenesis | biological process | GO:0003150 | 6 | 3 | 17256 | 1658 |
TGFBR3,BMP4,FZD1 |
| 1.417e-02 | -4.26 | prostaglandin transport | biological process | GO:0015732 | 6 | 3 | 17256 | 1658 |
ABCC2,ABCC4,SLCO3A1 |
| 1.422e-02 | -4.25 | regulation of organ morphogenesis | biological process | GO:2000027 | 249 | 35 | 17256 | 1658 |
RUNX2,ACVR1,BMPR2,LGR4,CELSR1,CELSR3,GATA3,FOXP2,DACT1,MYC,TFAP2A,PRICKLE2,GLI1,FZD1,ENAM,MSX1,FZD4,PRICKLE1,WNT11,ROR1,GPC6,FGFR1,DKK1,PTK7,CSF1,XBP1,SEMA3C,HOXD13,HGF,BMPR1A,PAX9,BMP4,MAGI2,MLLT3,SIX2 |
| 1.422e-02 | -4.25 | homotypic cell-cell adhesion | biological process | GO:0034109 | 55 | 11 | 17256 | 1658 |
TYRO3,SLC7A11,PTPRU,PTPN6,UBASH3B,DSG2,ITGB3,PKP2,GAS6,DSP,STXBP1 |
| 1.424e-02 | -4.25 | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | 129 | 21 | 17377 | 1707 |
FAM171B,ALDH2,TES,ST6GAL1,BACE1,MAFB,PRKCQ,PALLD,BEX2,GABARAPL1,DCBLD2,TRPS1,RASSF8,GSN,AK1,RIMKLB,PLAGL1,SGK1,STXBP1,PTGES,TBC1D8 |
| 1.424e-02 | -4.25 | CRX_DN.V1_DN | MSigDB lists | CRX_DN.V1_DN | 129 | 21 | 17377 | 1707 |
SKAP2,WWC1,CEBPA,PRDM1,CHAC1,ZDHHC14,SEL1L3,CRYBG3,JAM3,PYCR1,DHX32,CEBPB,BACH2,PLOD2,SH3BP4,RAI14,ZNF474,CADPS2,TRPC3,CEBPD,SMPDL3A |
| 1.426e-02 | -4.25 | - | gene3d domains | 1.20.900.10 | 70 | 14 | 8148 | 867 |
ARHGEF10L,VAV3,ARHGEF28,FARP1,ARHGEF11,RASGRF2,MCF2L2,MCF2L,PREX1,SPATA13,PLEKHG1,OBSCN,TIAM2,ARHGEF26 |
| 1.427e-02 | -4.25 | GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_DN | 161 | 25 | 17377 | 1707 |
CACNA1E,RAPGEF2,ST6GAL1,LRP4,SDC3,GPSM2,CDS1,ISG20,RTN1,TLR3,SETDB2,IKZF5,TRIM34,RND3,ABI3BP,KMO,PLOD2,FBRSL1,FAM84B,CMPK2,DENND1C,STXBP1,TNFRSF11A,MLLT3,MEF2C |
| 1.427e-02 | -4.25 | GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_DN | 161 | 25 | 17377 | 1707 |
FAM171B,GCA,PHLDB2,MYCBP2,CAPN5,MAFB,COBLL1,PRKCQ,ADAMTS6,SPATS2L,APBA1,SNTB1,IKZF2,WARS,HEG1,TLR3,MFSD9,CACNB2,AKT3,GNB4,ALDH1L1,UACA,STXBP1,RASGRP1,MED12L |
| 1.427e-02 | -4.25 | GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN | MSigDB lists | GSE26928_EFF_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN | 161 | 25 | 17377 | 1707 |
VNN2,SERINC5,MYCBP2,PPP4R4,KCNQ3,KLHL3,GALNT12,PLAG1,RIMKLA,TCEA3,CR2,STRADB,BBS9,ZNF558,HECTD2,GALNT1,IGF1R,FRAS1,INPP4B,MARCH3,NAP1L3,KLHL29,TC2N,CAND2,PCSK5 |
| 1.430e-02 | -4.25 | GPS | smart domains | SM00303 | 30 | 8 | 9493 | 1056 |
ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRG6,ADGRL2,ADGRB2,ADGRL1 |
| 1.430e-02 | -4.25 | response to extracellular stimulus | biological process | GO:0009991 | 489 | 62 | 17256 | 1658 |
PRKAA2,PCSK1N,ACSL1,BMPR2,IL15,ITGA6,LDLR,SELL,ASS1,CBS,CHSY1,GAS6,ADSSL1,CYP26A1,STK24,HMGCS1,ASNS,EEF2,ZNF354A,PMAIP1,BCHE,BHLHA15,STC2,SREBF1,CADPS2,PCK2,AGL,ATP2B1,RNF152,HMGCR,FADS1,TRPM4,GDAP1,SESN2,ATF4,ACVR1C,LRRK2,NUAK2,MARS,ATF3,WNT11,CD40,SESN1,LRAT,MGMT,BAIAP2,GABARAPL1,CXCL10,GSN,PEMT,CTSV,XBP1,ITGA2,ADRB1,PIK3C2B,ATG5,PPARGC1A,TRPC3,PSPH,LARP1,DDIT3,RRAGD |
| 1.433e-02 | -4.25 | extracellular matrix structural constituent | molecular function | GO:0005201 | 76 | 14 | 17224 | 1680 |
COL9A3,ENAM,COL4A3,FBN1,COL4A4,LAMB1,EMILIN2,TUFT1,COL19A1,COL4A5,BCAN,COL14A1,COL9A2,COL27A1 |
| 1.433e-02 | -4.25 | MODULE_121 | MSigDB lists | MODULE_121 | 98 | 17 | 17377 | 1707 |
VEGFC,IL15,TGFA,EPS8,GAS6,ISG20,CXCL10,INSIG1,MYC,CSF1,BCL6,NRP1,ZFP36L2,CHRM3,CSRP2,SFN,LAMP3 |
| 1.434e-02 | -4.24 | BROWNE_HCMV_INFECTION_24HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_UP | 137 | 22 | 17377 | 1707 |
RAB6B,ATP8A1,PLXNA2,AK4,WNT11,STAT5B,ABAT,KBTBD11,NEO1,HTR7,EPCAM,ABLIM1,UNC13B,CHRNA5,TNFRSF17,SYNGR3,NPTXR,TSPAN9,AGL,RASGRP1,OCLN,FOXA1 |
| 1.434e-02 | -4.24 | GO_SULFUR_COMPOUND_BINDING | MSigDB lists | GO_SULFUR_COMPOUND_BINDING | 227 | 33 | 17377 | 1707 |
FN1,CFH,SELL,CBS,NELL2,TGFBR3,SOAT2,ABI3BP,COL25A1,HS3ST5,GSTM3,PCOLCE2,SLIT2,PCSK6,FGFR4,GSTM2,WISP3,MSTN,GSTM4,OGDHL,FGF12,RYR2,FGFR1,GPC6,TPK1,ENPP1,CXCL10,ADAMTS3,THBS4,BMP4,NRP1,PTGES,ATP1A3 |
| 1.434e-02 | -4.24 | V$HNF1_C | MSigDB lists | V$HNF1_C | 227 | 33 | 17377 | 1707 |
PLA2G4A,CGN,NEK10,MXI1,SORBS1,SP8,NEO1,PLS3,TRPS1,ZNF827,ZNF362,BACE2,EEPD1,ACVR2A,MARCKS,PPP2R2B,TMEM37,NCAM1,ERRFI1,POU3F3,FGFR4,SSH3,TNS1,PRDM1,SGK2,ZFPM2,LRAT,NAALADL2,SLC39A14,CDH17,NRP1,FRMD5,LPP |
| 1.435e-02 | -4.24 | PRKCB (protein kinase C beta) | protein interactions | 5579 | 103 | 18 | 17029 | 1718 |
PDLIM7,ITGB7,FN1,BMPR2,GABRB2,GABRG2,CHUK,RACK1,PRKCA,PRKCB,ITGB3,PRKCD,TNFRSF1A,GRIN2D,MARCKS,NCAM1,STXBP1,OCLN |
| 1.436e-02 | -4.24 | GO_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 47 | 10 | 17377 | 1707 |
CEBPB,TRPM4,XBP1,CEBPA,KLF5,RARRES2,SH3PXD2B,SAV1,ZNF385A,SNAI2 |
| 1.436e-02 | -4.24 | GO_HEXOSE_CATABOLIC_PROCESS | MSigDB lists | GO_HEXOSE_CATABOLIC_PROCESS | 47 | 10 | 17377 | 1707 |
PFKFB4,GAPDH,ENO2,FUT9,PFKFB2,ALDOC,ALDOA,HK2,HK1,ENO1 |
| 1.436e-02 | -4.24 | YAMASHITA_LIVER_CANCER_STEM_CELL_UP | MSigDB lists | YAMASHITA_LIVER_CANCER_STEM_CELL_UP | 47 | 10 | 17377 | 1707 |
ROBO2,BACE2,PRKCD,MAPK13,SEMA3C,PLCB1,DDR1,PDGFRB,DUSP1,DKK1 |
| 1.436e-02 | -4.24 | KRAS.50_UP.V1_UP | MSigDB lists | KRAS.50_UP.V1_UP | 47 | 10 | 17377 | 1707 |
HTR7,TERT,ITGA2,KIF5C,SNAP25,FAM155B,ETV1,DYNC1I1,HEY1,GLDC |
| 1.437e-02 | -4.24 | negative regulation of GTPase activity | biological process | GO:0034260 | 48 | 10 | 17256 | 1658 |
TNK2,IPO5,LRRK2,SH3BP4,GPSM1,ARL2,PTPRN2,DAB2IP,SPRY2,SLIT2 |
| 1.438e-02 | -4.24 | Lysine degradation | KEGG pathways | hsa00310 | 59 | 12 | 7161 | 730 |
NSD1,ALDH2,SETDB2,AADAT,HYKK,EHHADH,PLOD2,AASS,OGDHL,COLGALT2,NSD2,PHYKPL |
| 1.438e-02 | -4.24 | Lysine degradation | KEGG pathways | ko00310 | 59 | 12 | 7161 | 730 |
NSD1,ALDH2,HYKK,SETDB2,EHHADH,AADAT,PLOD2,AASS,OGDHL,COLGALT2,NSD2,PHYKPL |
| 1.439e-02 | -4.24 | GO_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 943 | 113 | 17377 | 1707 |
CACNG3,SIDT1,GRIK2,ATP8A1,MCOLN3,SLC7A2,ITPR2,SLC2A13,CACNB4,SLCO3A1,SLC19A2,NCS1,SLC9A7,SLC22A17,KCNN2,KCNAB1,CHRNA5,SLC16A2,SLC22A18,SLC10A7,KCNS3,SERINC2,TRPC1,SLC2A12,TMEM37,SCN2A,ATP6AP1L,SCN3A,KCNB2,GPM6A,SLC3A2,KCNIP3,ABCC4,SFXN4,KCNH5,SLC39A8,GJB2,ATOX1,CHRNA6,ABCC2,KCND3,ATP1B1,GJC1,SLC39A14,SFXN1,SLC7A1,KCNMB4,ATP7B,KCNG1,SLC9B1,DENND5B,KCNV1,ANO10,SERINC5,SV2B,TMEM63C,SCN5A,SLC6A9,GABRB2,SCN8A,ATP6V1E2,GABRG2,SLC36A4,GABRR2,SLC12A6,SLC1A3,GAS6,SFXN3,KCNC4,MCU,MCOLN2,KCNJ4,SLC7A11,SLC30A4,SCN1B,ABCA5,CACNB2,KCNMB3,SLC16A9,SLC6A15,NIPAL2,SLCO4C1,SLC45A3,ATP2B1,TRPM4,SLC40A1,SLC37A1,KCNQ3,SLC36A1,CACNA1E,GRID1,TTYH2,RYR2,RASA3,STEAP1,TMCO3,KCNK15,GRIK4,MFSD2A,SLC2A6,SLC7A5,CDH17,SLCO5A1,GRIN2D,SLC22A15,SLC1A5,TRPC3,ATP2B4,CACNA2D1,SLC16A10,ATP1A3,ABCG1,SLC43A1 |
| 1.439e-02 | -4.24 | GO_REGULATION_OF_CELLULAR_LOCALIZATION | MSigDB lists | GO_REGULATION_OF_CELLULAR_LOCALIZATION | 1223 | 143 | 17377 | 1707 |
EXPH5,DOC2A,LGR4,TRIM16,SYT12,VAMP8,GATA3,LILRB1,ITPR2,ABAT,SYT14,PRKCA,NCS1,SEC16B,PMAIP1,RAB26,KCNS3,TRPC1,TLR4,MYRIP,RASGRP1,ACVR1C,WLS,ANK2,LRRK2,JPH1,ELMOD1,BNIP3L,SERGEF,TRIM9,GSN,KCNMB4,INSIG1,BBC3,INPP5F,OXTR,TNFSF4,MAGI2,TC2N,MEF2C,STXBP5L,FN1,BVES,STXBP6,UBASH3B,BTBD9,MLC1,PFN2,IL18R1,GAS1,SREBF1,CADPS2,STXBP1,RIMS2,HMGCR,RHOQ,RAPGEF4,RYR2,WWC1,PLS1,SNAP25,PLCB1,RPL28,CDH2,TRPC3,SFN,SORBS1,AKAP5,RGS20,NRXN1,PPP1R9A,PCLO,TLR3,UNC13B,DACT1,REEP1,DAB2IP,MARCKS,PDE4D,RAB27B,SNAI2,FZD1,GAB2,DPP10,FER,PFKFB2,PTPN6,CHRNA6,GSTO1,PRKCQ,SYNJ2BP,CD40,ASPH,SNCA,IRS2,SMAD3,CXCL10,PEMT,GBP1,WWTR1,PAM,BMPR1A,ATG5,SEPT5,MXI1,C1QTNF3,CD276,LRP4,APBB1,IPO5,UBAC2,ARL2,P2RY1,GAS6,KCNC4,BMP6,NEDD4,MCU,NKX6-1,RAB11FIP5,PRKCD,SYK,FES,TRPM4,VEGFC,RAB3B,GSTM2,KDM5B,CACNA1E,SYBU,LITAF,TLR6,MAP1B,GPLD1,ZIC1,FGR,ICA1,TERT,XBP1,BMP4,IL9R,PKIA,STOM |
| 1.442e-02 | -4.24 | serine family amino acid biosynthetic process | biological process | GO:0009070 | 16 | 5 | 17256 | 1658 |
CBS,SERINC5,PHGDH,PSPH,CTH |
| 1.442e-02 | -4.24 | positive regulation of natural killer cell activation | biological process | GO:0032816 | 16 | 5 | 17256 | 1658 |
STAT5B,TOX,GAS6,IL15,RASGRP1 |
| 1.442e-02 | -4.24 | cell migration involved in heart development | biological process | GO:0060973 | 16 | 5 | 17256 | 1658 |
BVES,FLRT3,PDGFRB,DCHS1,SNAI2 |
| 1.442e-02 | -4.24 | response to epinephrine | biological process | GO:0071871 | 16 | 5 | 17256 | 1658 |
RYR2,PDE4D,PPARGC1A,ATP2B4,SNCA |
| 1.442e-02 | -4.24 | mesenchymal cell proliferation | biological process | GO:0010463 | 16 | 5 | 17256 | 1658 |
MSX1,BMP4,FAT4,SIX2,DCHS1 |
| 1.442e-02 | -4.24 | YATGNWAAT_V$OCT_C | MSigDB lists | YATGNWAAT_V$OCT_C | 338 | 46 | 17377 | 1707 |
LRFN5,NEK10,SORBS1,ITPRIP,REL,CADM2,LACC1,NRXN1,FOXG1,HPCAL4,NEDD4,PPP2R3A,MTUS1,TRPS1,TUBB4A,ATXN7L1,LRRN1,BACE2,COL25A1,LHX6,RAB26,SCRN1,CCDC122,PRICKLE2,SLC6A15,TSPAN13,DNAH5,ETV1,SEMA6C,ENAM,FZD4,NR6A1,FGF12,NFIA,PRDM1,ATOH1,TCERG1L,MBNL2,CA13,EML1,MAP1B,NAP1L5,GPRC5B,MCC,DLG2,MID1 |
| 1.443e-02 | -4.24 | bounding membrane of organelle | cellular component | GO:0098588 | 2039 | 221 | 18223 | 1724 |
DOC2A,ACSL1,CACNG3,ATP8A1,SYT12,DNAJC3,VAMP8,LDLR,MCOLN3,ASS1,MGAT5B,ITPR2,NOS1AP,CHST10,SLC9A7,PCDH7,RND2,SEC16B,TM9SF2,PMAIP1,ZFYVE28,ITGB3,RAP2A,RAB26,TMED9,COG3,PPP2R2B,GALNT18,TLR4,CPE,RASGRP1,LAMP3,ATL1,GDAP1,GCNT2,CD55,ERGIC1,ABCC4,TGFA,WLS,JPH1,LRMP,LRRK2,BNIP3L,GNAI1,SPNS1,ENPP1,TMEM150B,HPSE,NCKAP1L,ENTPD7,GNB4,ATP7B,B3GALT2,TNFRSF1A,DSEL,INPP5F,SPART,CHMP4C,RRAGD,UST,SV2B,LGALS3,SEC24D,HID1,ST6GAL1,DHCR24,GALNT13,SLC36A4,CHSY1,BBS9,MCOLN2,GBGT1,GALNT1,SLC30A4,ABCA5,SREBF1,HS3ST5,LRP6,BNIP3,LMAN2,ST8SIA1,SLCO4C1,NCAM1,MOXD1,FAR2,GPR161,CKAP4,NOS3,RNF152,HMGCR,CHSY3,IL17RD,QSOX1,RHOQ,PLEKHA8,SLC27A2,SLC36A1,VLDLR,MGAT4B,GPSM1,RYR2,HIP1,GALNT17,PEX5L,ST6GALNAC3,SNAP25,B4GALNT3,CLN5,STEAP1,TMEM74,GLCE,VPS37D,SH3GL2,PMEPA1,QPCTL,HK2,RAB31,PTPRN2,LAPTM4B,PLD1,DHCR7,DIRC2,MME,FRMPD3,DMXL2,SCAMP1,TCTN2,RNF144A,RHOD,LPCAT2,GALNT6,GALNT12,XYLT1,MYO1B,MSR1,RNF24,FAM198B,ZFYVE9,CD53,TLR3,UNC13B,SLC22A17,KMO,STEAP3,PROS1,CLVS2,RAB27B,SYNGR3,SNX10,ANTXR2,EVA1A,TMEM67,B3GALT1,FZD4,SHANK2,RNF125,SYNJ2BP,RAB38,PXYLP1,ASPH,DSP,GABARAPL1,SNCA,ARHGAP21,PTPRJ,GBP1,PAM,PTPRS,MAOA,HS3ST3B1,ATG5,RAB30,ARFGEF3,HACE1,MAN2B2,GRB14,TSPAN15,ATP9A,BACE1,CLSTN2,SELL,USP30,EPHB1,NDFIP2,TTC1,RAB11FIP5,TECPR1,MGAT1,FUT9,EHD3,KIAA0319,MARCH3,FIG4,MYO6,B4GALT6,RAB3B,RAB6B,CYTH3,SYBU,LITAF,PHACTR2,ARHGAP32,ATP11A,FNDC3A,GALNT14,TLR6,GPLD1,DKK1,PTPRC,GALNT3,ICA1,PLOD2,RND3,PRCP,ACER2,HK1,CERS1,B4GALT7,STOM,ABCG1 |
| 1.447e-02 | -4.24 | negative regulation of MAPK cascade | biological process | GO:0043409 | 173 | 26 | 17256 | 1658 |
PRKN,DUSP8,PTPN6,DUSP9,NDRG2,ATF3,SYNJ2BP,MECOM,CAMK2N1,PTPRJ,IGF1R,DACT1,CNKSR3,GBP1,MYC,PRKCD,C1QL4,DUSP19,DAB2IP,BMP4,SPRY4,ERRFI1,TLR4,SPRY2,HMGCR,DUSP1 |
| 1.447e-02 | -4.24 | sulfur compound biosynthetic process | biological process | GO:0044272 | 173 | 26 | 17256 | 1658 |
UST,CHSY3,OPLAH,ACSL1,GSTM2,MGST3,GSTM4,XYLT1,ELOVL7,ELOVL3,FASN,HACD1,CBS,SCD,GSTO1,CHSY1,CHAC1,BCAN,TPK1,GLCE,GSTO2,GSTM3,DSEL,ESD,CTH,B4GALT6 |
| 1.450e-02 | -4.23 | pyridine-containing compound metabolic process | biological process | GO:0072524 | 116 | 19 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,PFKFB2,OGDHL,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,MDH1B,PCK2,ENO1,PARP9,NUDT17 |
| 1.451e-02 | -4.23 | GO_CRANIAL_SKELETAL_SYSTEM_DEVELOPMENT | MSigDB lists | GO_CRANIAL_SKELETAL_SYSTEM_DEVELOPMENT | 54 | 11 | 17377 | 1707 |
SMAD3,RUNX2,INSIG1,WDR19,TFAP2A,DLX2,BMP4,HOXA1,MMP16,SIX2,MEF2C |
| 1.451e-02 | -4.23 | GO_PHOSPHOLIPID_TRANSPORT | MSigDB lists | GO_PHOSPHOLIPID_TRANSPORT | 54 | 11 | 17377 | 1707 |
ATP9A,ATP8A1,MFSD2A,OSBPL5,PRELID2,LDLR,PRELID1,ATP11A,NPC2,ATP10D,ABCG1 |
| 1.451e-02 | -4.23 | GO_ACTIN_CYTOSKELETON_REORGANIZATION | MSigDB lists | GO_ACTIN_CYTOSKELETON_REORGANIZATION | 54 | 11 | 17377 | 1707 |
PAK1,GSN,TNIK,FER,FRY,PTK7,GPR65,RAP2A,EPS8,CTTN,CDC42BPA |
| 1.451e-02 | -4.23 | WIERENGA_STAT5A_TARGETS_GROUP2 | MSigDB lists | WIERENGA_STAT5A_TARGETS_GROUP2 | 54 | 11 | 17377 | 1707 |
ANTXR2,CXCL10,CA2,RNF217,GPR65,ARID5B,MAPK13,PRDM8,CKAP4,LAMP3,GABARAPL1 |
| 1.451e-02 | -4.23 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 | 244 | 35 | 17377 | 1707 |
ACSL1,CHCHD7,AASS,PTPRD,RECK,HEBP1,CYP4V2,CBS,NDRG2,ABAT,GAS1,EPDR1,EFEMP1,AADAT,ABI3BP,SLC16A2,CFHR1,GHR,MPDZ,PCOLCE2,IL1RAP,CTH,TBC1D8,GPM6A,PDK1,CACNA1E,CALCRL,GSTO1,ATP11A,PLEKHB1,GABARAPL1,HPGD,ATG5,SUSD4,KIF1B |
| 1.453e-02 | -4.23 | brown fat cell differentiation | biological process | GO:0050873 | 28 | 7 | 17256 | 1658 |
CEBPB,BNIP3,CEBPA,ZNF516,PPARGC1A,ITGA6,ADRB1 |
| 1.457e-02 | -4.23 | neuron projection membrane | cellular component | GO:0032589 | 56 | 11 | 18223 | 1724 |
EPB41L3,MYO1D,ATF4,RIPOR2,ROBO2,WLS,MPP2,GABRG2,KCNC4,ATP2B1,GABARAPL1 |
| 1.458e-02 | -4.23 | GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_DN | MSigDB lists | GSE19888_CTRL_VS_TCELL_MEMBRANES_ACT_MAST_CELL_PRETREAT_A3R_INH_DN | 194 | 29 | 17377 | 1707 |
MOCOS,RGS16,ITGB7,EIF4E3,IL15,PTPN6,STAT5B,NPC2,SPATS2L,RARRES2,LACC1,CD40,INPP1,CXCL10,TLR3,SETDB2,TRIM34,PIK3AP1,GNB4,UACA,SFMBT1,HK1,CMPK2,STXBP1,SLFN5,SNX10,LARP1,ABCG1,PARP9 |
| 1.458e-02 | -4.23 | GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_WT_VS_ID2_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | 194 | 29 | 17377 | 1707 |
GNG12,MEIS2,RAB3B,GCNT2,TCTN2,FHL2,HIP1,PDE8A,NDFIP2,WARS,SMAD3,DOCK7,SH3RF1,KMO,MYC,THBS4,RBPMS2,AKT3,SRD5A3,RAI14,HK2,POF1B,SH3BGRL2,PIP5KL1,KLF9,TMEM37,PCOLCE2,CRISPLD1,MME |
| 1.458e-02 | -4.23 | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP | 194 | 29 | 17377 | 1707 |
IL15,STAT4,SELL,ACVR2B,FAM198B,GAS6,PEAK1,BEX2,TSPAN17,SNCA,GABARAPL1,HOMER3,PTPRC,TRIB3,ICA1,RALGPS2,PRKCB,MAP2K6,OSBPL5,MAOA,ADCY6,ZNF808,DBP,OXTR,DOCK6,DCBLD1,BTRC,MEF2C,IGFBP3 |
| 1.459e-02 | -4.23 | KCTD3 (potassium channel tetramerization domain containing 3) | protein interactions | 51133 | 126 | 21 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,TBC1D1,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,BAIAP2,NAV1,KCTD15,RALGPS2,MAP3K21,TANC2,STXBP1,OSBPL6,KIF1B,KCTD1,LARP1,GAB2 |
| 1.464e-02 | -4.22 | DNAAF2 (dynein axonemal assembly factor 2) | protein interactions | 55172 | 81 | 15 | 17029 | 1718 |
DPYSL5,GPM6A,DNM3,RAB6B,ANK2,GNAO1,SNAP25,SFXN3,NCAM1,SEPT3,STXBP1,HPCAL4,CACNA2D1,SNCA,CNTN1 |
| 1.464e-02 | -4.22 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 417 | 55 | 17377 | 1707 |
PRKAA2,C1QTNF3,RASAL2,DUSP8,NDRG2,PIBF1,DDIT4,MECOM,IGF1R,DACT1,CNKSR3,FLRT3,MYC,PRKCD,C1QL4,BCL6,DAB2IP,WWC2,ERRFI1,TLR4,SPRY2,SLIT2,ZNF385A,SNAI2,RNF152,HMGCR,DUSP1,GSTM2,MSTN,PTPN6,LRRK2,DEPTOR,LITAF,DUSP9,RASA3,WWC1,ATF3,GSTO1,SYNJ2BP,PLEKHA1,HERPUD1,PTPRJ,MYADM,GBP1,WFS1,XBP1,SH3BP4,DUSP19,INPP5F,SPRY4,BMP4,MAGI2,DDIT3,ATP2B4,TPT1 |
| 1.469e-02 | -4.22 | RHO | prosite domains | PS51420 | 20 | 6 | 12060 | 1278 |
RND2,RHOQ,RND3,RHOBTB1,RHOD,RAC3 |
| 1.472e-02 | -4.22 | learning or memory | biological process | GO:0007611 | 241 | 34 | 17256 | 1658 |
PRKN,PDE1B,FGF13,PAK5,ATP8A1,LDLR,BTBD9,NRXN1,FOXP2,KCNAB1,MAP1A,BCHE,AFF2,SGK1,GATM,ZNF385A,HMGCR,BDNF,MEIS2,VLDLR,SHANK2,ADCY1,NLGN4X,PRKAR2B,SNAP25,PLCB1,DKK1,CEBPB,ADGRB3,PLK2,ASIC1,TMOD2,OXTR,MEF2C |
| 1.473e-02 | -4.22 | PLTP (phospholipid transfer protein) | protein interactions | 5360 | 33 | 8 | 17029 | 1718 |
EPB41L5,UGT8,CANX,ITPRIP,SEL1L3,CLGN,PGAP1,GPC6 |
| 1.473e-02 | -4.22 | IL2RG (interleukin 2 receptor subunit gamma) | protein interactions | 3561 | 33 | 8 | 17029 | 1718 |
PTPRJ,IL15,PTPRD,IL13RA1,NDFIP2,ERRFI1,IL9R,NEDD4 |
| 1.473e-02 | -4.22 | WIPF1 (WAS/WASL interacting protein family member 1) | protein interactions | 7456 | 33 | 8 | 17029 | 1718 |
BAG3,PRKCQ,CTTN,PACSIN1,APBB1,GAN,PACSIN3,HOMER3 |
| 1.473e-02 | -4.22 | ITM2B (integral membrane protein 2B) | protein interactions | 9445 | 33 | 8 | 17029 | 1718 |
AMIGO1,TGFBR3,SEMA4F,NAALADL2,SEMA6A,PGAP1,CACNA2D1,DCBLD2 |
| 1.475e-02 | -4.22 | Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | REACTOME pathways | R-HSA-381676 | 42 | 9 | 10287 | 971 |
GNG12,AKAP5,GNB4,RAPGEF4,KCNS3,ADCY6,PRKAR2B,ITPR2,PRKACB |
| 1.477e-02 | -4.22 | PSI | smart domains | SM00423 | 42 | 10 | 9493 | 1056 |
ITGB7,SEMA4F,PLXDC2,ITGB3,PLXNA2,ATRNL1,SEMA3C,MET,SEMA3A,SEMA6A |
| 1.478e-02 | -4.21 | regulation of muscle contraction | biological process | GO:0006937 | 165 | 25 | 17256 | 1658 |
TRPM4,SCN5A,GSTM2,FGF13,ANK2,RYR2,PKP2,CALCRL,GSTO1,ATP1B1,ABAT,DSP,DOCK5,NOS1AP,EHD3,DSG2,ITGA2,PRKG1,OXTR,PDE4D,CTTN,TPM1,ENO1,KCNB2,CHRM3 |
| 1.478e-02 | -4.21 | netrin receptor activity | molecular function | GO:0005042 | 6 | 3 | 17224 | 1680 |
UNC5C,UNC5B,DCC |
| 1.478e-02 | -4.21 | G-protein coupled glutamate receptor binding | molecular function | GO:0035256 | 6 | 3 | 17224 | 1680 |
NECAB2,HOMER2,HOMER3 |
| 1.478e-02 | -4.21 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway | molecular function | GO:1904929 | 6 | 3 | 17224 | 1680 |
ROR1,PTK7,GPC6 |
| 1.478e-02 | -4.21 | BMP receptor activity | molecular function | GO:0098821 | 6 | 3 | 17224 | 1680 |
ACVR2A,BMPR1A,BMPR2 |
| 1.478e-02 | -4.21 | phosphatidic acid transporter activity | molecular function | GO:1990050 | 6 | 3 | 17224 | 1680 |
PLTP,PRELID2,PRELID1 |
| 1.481e-02 | -4.21 | GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_UP | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_UP | 186 | 28 | 17377 | 1707 |
DMXL2,PDLIM7,QSOX1,USP2,IGFBP6,SCAMP1,HEBP1,RNF24,IL13RA1,NDFIP2,ARRDC4,ADSSL1,MTUS1,TMEM53,IGF1R,CSF1,PELI2,PLXDC2,EIF4EBP1,RAP2A,EMILIN2,FAM107B,PRELID1,ATRNL1,MARCH3,BEND4,MAPK13,ALPK1 |
| 1.481e-02 | -4.21 | GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_DN | MSigDB lists | GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_DN | 186 | 28 | 17377 | 1707 |
DMXL2,GCA,UGT8,DYRK3,SEC24D,ATP9A,IL13RA1,HOXA1,ATP10D,SLC19A2,STEAP1,HOPX,FRY,UNC13B,RPL28,AFF2,ATP7B,MAP7,SQLE,PTPRN2,SERPINI1,DHRS12,GULP1,TNFRSF17,ZNF460,SMPDL3A,ZNF629,PCSK5 |
| 1.481e-02 | -4.21 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_HEXOSYL_GROUPS | 186 | 28 | 17377 | 1707 |
CHSY3,CCDC126,UGT8,GCNT2,B3GALT1,GALNT12,GALNT6,XYLT1,MGAT4B,ALG1L,GALNT13,CHSY1,MGAT5B,B4GALNT3,GALNT14,GALNT3,DPY19L2,GALNT1,TYMP,GBGT1,FUT9,MGAT1,B3GALT2,ALG11,AGL,B4GALT7,ALG10B,B4GALT6 |
| 1.481e-02 | -4.21 | GSE17721_LPS_VS_CPG_12H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_12H_BMDC_DN | 186 | 28 | 17377 | 1707 |
DOC2A,EHHADH,SIDT1,PPFIBP2,MSR1,IGF2BP2,SORBS3,OR51B4,LCP2,DNER,ASPH,NEDD4,CD53,EPCAM,GPRC5B,WFS1,MYC,ZDHHC6,RAB31,RAI14,TFAP2A,POF1B,PCK2,MET,NRP1,DDIT3,ACSM3,B4GALT6 |
| 1.481e-02 | -4.21 | GSE13306_RA_VS_UNTREATED_TREG_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_TREG_DN | 186 | 28 | 17377 | 1707 |
VNN2,EIF4E3,MARK1,TMEM65,CKAP2,PSTPIP2,YPEL2,TTYH2,GABRG2,RNF125,NTRK3,GABRR2,IL18R1,PHLDA2,EPDR1,BEX4,FBXO32,EEF2,C1orf21,SCRN1,P4HA1,NEK11,SHF,RNF130,MYO6,DOCK6,KIF1B,MME |
| 1.481e-02 | -4.21 | GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 186 | 28 | 17377 | 1707 |
MOB1B,GCA,GNG12,ACSL1,ZNF516,ABCC4,TMEM43,GRB14,STXBP6,LRP4,AK4,CTBP2,PLCB1,DSP,DACH2,TTC30B,SLC19A2,SCIN,GALNT1,ICA1,CLDN12,REEP1,RAP2A,TECPR2,SFMBT1,SGK1,STOM,SNX7 |
| 1.481e-02 | -4.21 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_UP | 186 | 28 | 17377 | 1707 |
ITGB7,CRIM1,REL,JDP2,CYTH3,YPEL2,ABHD4,SNX9,PEAK1,TTC30B,MCU,SCIN,RERE,SKI,HOPX,MAPKAPK2,GPR15,KIAA1958,TEX15,ICA1,BACH2,RALGPS2,PLOD2,BCL6,PTPRS,GFI1,RAPGEF5,ABCG1 |
| 1.481e-02 | -4.21 | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP | MSigDB lists | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP | 186 | 28 | 17377 | 1707 |
ROBO2,RNF170,SLC27A2,RAPGEF2,FOXN3,EXOC6B,ATF7IP2,LITAF,RGS20,NPC2,CCNG1,SEL1L3,DSP,TTLL7,TMEM74,GLCE,SLC39A14,PPM1E,TLR3,TMEM237,SLC30A4,GRHL1,PPFIBP1,RBPMS2,BCL6,RALGAPA2,ERCC5,IL1RAP |
| 1.481e-02 | -4.21 | GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_UP | MSigDB lists | GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_UP | 186 | 28 | 17377 | 1707 |
TNK2,SLC40A1,MXI1,EHHADH,SIDT1,SEC24D,TBC1D1,GALNT6,VAMP8,EDEM3,NUAK2,UBAC2,CHUK,FAM117B,CBY1,GRK6,CD40,SPATA7,RERE,TLR3,KMO,MARVELD2,SLCO5A1,SVIL,SERPINI1,LIFR,CKAP4,MEF2C |
| 1.481e-02 | -4.21 | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | 186 | 28 | 17377 | 1707 |
MICAL2,LGALS3,GPR65,RAPGEF2,MLF1,ARID5B,TTYH2,PHACTR2,PRDM1,COTL1,BATF,TSPAN17,HERPUD1,ENTPD1,TIFA,TGFBR3,ZFYVE28,AKT3,PRKCD,NCOA7,EEPD1,TUFT1,ST8SIA1,FAR2,KIF1B,ATP2B4,LPP,STOM |
| 1.481e-02 | -4.21 | GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_UP | MSigDB lists | GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_UP | 186 | 28 | 17377 | 1707 |
MID2,PHLDB2,TMEM67,ANKRD13D,FLVCR2,LGR4,PFKFB2,C3orf52,LRRCC1,RHPN2,ST6GALNAC3,TNS1,ATP11A,SESN1,CTNNA2,IRS2,TMEM53,NSD1,ABI3BP,TACC2,CLDN12,MPP2,TFAP2A,B3GALT2,SERPINI1,FAR2,SNAI2,HEY1 |
| 1.481e-02 | -4.21 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | 186 | 28 | 17377 | 1707 |
LATS2,B3GALT1,ENO2,STAT4,GJB2,CD276,LDLR,DHCR24,FHDC1,EDEM3,LITAF,RASD1,NDFIP2,ADSSL1,SNX9,PLCB1,DYNC1I1,SCIN,HOMER3,INHBC,SUGT1,SLC7A11,KPNA3,PLK2,ADCY6,PTGES,LARP1,PCSK5 |
| 1.481e-02 | -4.21 | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN | MSigDB lists | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN | 186 | 28 | 17377 | 1707 |
CXCR5,MYCBP2,ANTXR2,INPPL1,PDK1,TTC39B,SKAP2,PTPN13,ITGA6,CYP4V2,SELL,CR2,RABAC1,ATP11A,IL18R1,GLCE,SKI,CA2,PRKCD,ZBTB20,ST8SIA1,PJA1,RCAN3,NRP1,SNX10,ZFP36L2,DUSP1,TPT1 |
| 1.481e-02 | -4.21 | GSE36009_WT_VS_NLRP10_KO_DC_UP | MSigDB lists | GSE36009_WT_VS_NLRP10_KO_DC_UP | 186 | 28 | 17377 | 1707 |
PLA2G4A,GPT2,RIN2,CARD6,GCNT2,CRIM1,GRIK2,RASA3,ATF3,FNDC3A,IKZF2,INPP1,CDS1,ISG20,FOXP2,CHRNA5,PIK3AP1,CSF1,MARVELD2,UACA,CAB39L,PROS1,ETV1,SLFN5,VGLL4,SPRY2,DOCK8,LARP1 |
| 1.481e-02 | -4.21 | GSE3039_CD4_TCELL_VS_B2_BCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_B2_BCELL_UP | 186 | 28 | 17377 | 1707 |
ARHGAP26,EIF4E3,FN1,CFH,BTNL9,NR4A1,ARL15,BACE1,MCTP2,MAFB,MAPK4,INPP1,BBS9,DSP,PTPRC,SYCP2,CPNE2,PPM1E,KIAA0895,MFSD9,SEC16B,PLAGL1,MPP7,GHR,PDE4D,NCAM1,PLTP,SMPDL3A |
| 1.481e-02 | -4.21 | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 186 | 28 | 17377 | 1707 |
UST,MPZL3,PDE1B,FLVCR2,SH2D2A,CRIM1,MVD,ARID5B,TTYH2,PHACTR2,STAT5B,SAV1,BATF,GPR137C,SLCO3A1,GABARAPL1,MAPKAPK2,CHN1,ENTPD1,TGFBR3,CACNB2,TOX,MPDZ,KIF21A,ST8SIA1,NIPAL2,TSHR,STOM |
| 1.481e-02 | -4.21 | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP | 186 | 28 | 17377 | 1707 |
DBN1,ZNF516,EIF4E3,EVL,RNF145,BMPR2,TBC1D1,TES,PLEKHA5,PTPN6,PPFIBP2,WNT11,PRDM1,DENND3,DOCK2,HERPUD1,RTN1,FBXO32,GPRC5B,PIK3AP1,NCKAP1L,PRKCB,GNB4,ABI3,SCRN1,RRAS2,FMNL2,MEF2C |
| 1.481e-02 | -4.21 | GSE30083_SP2_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP2_VS_SP4_THYMOCYTE_DN | 186 | 28 | 17377 | 1707 |
RIN2,RHOQ,TTC39B,SKAP2,SIDT1,ST14,RNF144A,STAT4,ITGA6,MCTP2,CYP4V2,RASA3,AGAP2,NTRK3,GABRR2,IL18R1,ATP10D,HOPX,TMEM150B,KCNN2,HPSE,SGK1,HS3ST3B1,IPCEF1,GEM,NRP1,SNX10,SMPDL3A |
| 1.484e-02 | -4.21 | HELP | pfam domains | PF03451 | 6 | 3 | 17054 | 1666 |
EML5,EML6,EML1 |
| 1.484e-02 | -4.21 | MAPEG | pfam domains | PF01124 | 6 | 3 | 17054 | 1666 |
ALOX5AP,PTGES,MGST3 |
| 1.484e-02 | -4.21 | LCCL | pfam domains | PF03815 | 6 | 3 | 17054 | 1666 |
DCBLD1,CRISPLD1,DCBLD2 |
| 1.484e-02 | -4.21 | C4 | pfam domains | PF01413 | 6 | 3 | 17054 | 1666 |
COL4A5,COL4A3,COL4A4 |
| 1.488e-02 | -4.21 | BLUM_RESPONSE_TO_SALIRASIB_UP | MSigDB lists | BLUM_RESPONSE_TO_SALIRASIB_UP | 236 | 34 | 17377 | 1707 |
CARS,ACVR1,BLVRB,CBS,SEZ6L2,CANX,PHGDH,INPP1,AARS,RSL24D1,ASNS,EEF2,MGAT1,EIF1,STC2,PJA1,CTH,ULBP1,QSOX1,ATF4,GARS,CD55,ANK2,MARS,ATF3,VIM,HOXA1,WARS,ISG20,TRIB3,RPL12,EIF4EBP1,XBP1,SLC1A5 |
| 1.488e-02 | -4.21 | GO_GTPASE_ACTIVITY | MSigDB lists | GO_GTPASE_ACTIVITY | 236 | 34 | 17377 | 1707 |
MTG1,DNM3,RHOD,ARL2,TUBE1,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,RASD2,RAP2A,RAB26,RAB27B,ARL4D,RRAS2,ATL1,RHOQ,RAB3B,TUBA1A,RAB6B,LRRK2,RAB38,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,GEM,SEPT5,RAB30,RRAGD |
| 1.492e-02 | -4.21 | PyrdxlP-dep_Trfase_dom1 | interpro domains | IPR015422 | 34 | 8 | 18492 | 1811 |
GPT2,MOCOS,GCAT,PHYKPL,ABAT,ETNPPL,CTH,GLDC |
| 1.492e-02 | -4.21 | GPS | interpro domains | IPR000203 | 34 | 8 | 18492 | 1811 |
ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRG6,ADGRL2,ADGRB2,ADGRL1 |
| 1.494e-02 | -4.20 | HR1_rpt_sf | interpro domains | IPR036274 | 6 | 3 | 18492 | 1811 |
RHPN2,PKN1,PKN3 |
| 1.494e-02 | -4.20 | ELO_CS | interpro domains | IPR030457 | 6 | 3 | 18492 | 1811 |
ELOVL4,ELOVL7,ELOVL3 |
| 1.494e-02 | -4.20 | Collagen_IV_NC_sf | interpro domains | IPR036954 | 6 | 3 | 18492 | 1811 |
COL4A5,COL4A3,COL4A4 |
| 1.494e-02 | -4.20 | LCCL_sf | interpro domains | IPR036609 | 6 | 3 | 18492 | 1811 |
DCBLD1,CRISPLD1,DCBLD2 |
| 1.494e-02 | -4.20 | Collagen_IV_NC | interpro domains | IPR001442 | 6 | 3 | 18492 | 1811 |
COL4A5,COL4A3,COL4A4 |
| 1.494e-02 | -4.20 | Membr-assoc_MAPEG | interpro domains | IPR001129 | 6 | 3 | 18492 | 1811 |
ALOX5AP,PTGES,MGST3 |
| 1.494e-02 | -4.20 | LCCL | interpro domains | IPR004043 | 6 | 3 | 18492 | 1811 |
DCBLD1,CRISPLD1,DCBLD2 |
| 1.494e-02 | -4.20 | MAPEG-like_dom_sf | interpro domains | IPR023352 | 6 | 3 | 18492 | 1811 |
ALOX5AP,PTGES,MGST3 |
| 1.494e-02 | -4.20 | HELP | interpro domains | IPR005108 | 6 | 3 | 18492 | 1811 |
EML5,EML6,EML1 |
| 1.498e-02 | -4.20 | negative regulation of transcription by RNA polymerase II | biological process | GO:0000122 | 805 | 96 | 17256 | 1658 |
TFCP2L1,PRKN,ID1,LMCD1,GATA3,BCL6B,CEBPA,IKZF2,TRPS1,SKI,BAG3,IKZF5,EOMES,DACT1,BCL6,DAB2IP,WWC2,ENO1,SNAI2,NKX2-1,KCNIP3,MEIS2,NOP53,NR6A1,PRDM13,NKX3-2,NFIA,ATF3,SATB2,ACVR2B,TCERG1L,FRK,FGFR1,SNCA,BCL11A,BATF3,AHRR,SMAD3,MSC,KLF12,BACH2,WFS1,WWTR1,ZBTB20,KLF5,DLX2,KCTD1,MEF2C,HEY1,KLF8,MXI1,ZHX3,REL,FZD8,JDP2,APBB1,SORBS3,ZNF219,SATB1,FOXG1,BMP6,NEDD4,NKX6-1,FOXP2,ZNF354A,GATA2,MYC,SREBF1,TFAP2A,YBX3,GFI1,GLIS1,PARP9,USP2,MSX1,ARID5B,VLDLR,FHL2,WWC1,NSD2,PRDM1,ZFPM2,DKK1,RERE,CEBPB,TRIB3,NSD1,ID3,NACC2,HEYL,PCGF2,BMP4,SHOX2,PKIA,FOXA1,DDIT3 |
| 1.499e-02 | -4.20 | TRPC1 (transient receptor potential cation channel subfamily C member 1) | protein interactions | 7220 | 21 | 6 | 17029 | 1718 |
TRPC1,ITPR2,BMPR2,TRPC3,TNFRSF1A,HOMER3 |
| 1.499e-02 | -4.20 | MATN2 (matrilin 2) | protein interactions | 4147 | 21 | 6 | 17029 | 1718 |
COL4A5,NELL2,COL4A3,FN1,COL4A4,MATN2 |
| 1.499e-02 | -4.20 | NXPH2 (neurexophilin 2) | protein interactions | 11249 | 21 | 6 | 17029 | 1718 |
CELSR1,FAT4,NRXN1,FAT1,FRAS1,PCDH7 |
| 1.499e-02 | -4.20 | MYLK (myosin light chain kinase) | protein interactions | 4638 | 21 | 6 | 17029 | 1718 |
PRKG2,PAK1,CTTN,PRKCA,MLC1,MYC |
| 1.499e-02 | -4.20 | ADGRB1 (adhesion G protein-coupled receptor B1) | protein interactions | 575 | 21 | 6 | 17029 | 1718 |
LIN7A,SNTB1,MAGI2,BAIAP2,MAGI3,PATJ |
| 1.499e-02 | -4.20 | NAT14 (N-acetyltransferase 14 (putative)) | protein interactions | 57106 | 21 | 6 | 17029 | 1718 |
SLC7A1,VNN2,RABAC1,CPVL,KCNC4,TTC30B |
| 1.501e-02 | -4.20 | Metabolism of lipids and lipoproteins | REACTOME pathways | R-HSA-556833 | 813 | 95 | 10287 | 971 |
PLA2G4A,UGT8,MVK,ACSL1,ELOVL4,LPCAT2,PLEKHA5,LDLR,TNFAIP8L2,LPIN3,ABHD4,TIAM2,CDS1,CYP51A1,PLPP1,IDI1,GRHL1,FAAH2,STARD4,FABP6,PLTP,PRKACB,HRASLS,CYP1B1,MVD,GDPD1,PLPP2,HACD1,YAP1,PLEKHA1,ETNPPL,AHRR,INSIG1,ENPP6,PEMT,WWTR1,INPP4B,BDH2,BMP1,HPGD,PIK3C2B,INPP5F,CYP2U1,PPARGC1A,MBOAT2,PCSK5,PRKAA2,INPPL1,ALOX5AP,EHHADH,SEC24D,CYP2J2,ELOVL7,DHCR24,OLAH,SCD,GDPD5,HMGCS1,SOAT2,MSMO1,BCHE,SREBF1,MED7,FIG4,CERS4,NCEH1,FAR2,HMGCR,CES3,PCSK6,FADS1,SLC27A2,PLEKHA8,AGPAT4,PTPN13,ELOVL3,VLDLR,FASN,FHL2,SMARCD3,NPC2,MAPKAPK2,TRIB3,MFSD2A,ACER2,OSBPL5,SRD5A3,SQLE,PLD1,CERS1,DHCR7,OSBPL6,PTGES,ACSM3,ABCG1 |
| 1.502e-02 | -4.20 | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_UP | 178 | 27 | 17377 | 1707 |
PDLIM7,MN1,GAPDH,PNP,SLC39A8,PSTPIP2,ELOVL7,NFE2L1,LILRB1,DNER,TBC1D16,TBC1D30,STEAP1,DDIT4,SLC7A11,MFSD2A,ALDOA,BCL6,STEAP3,HS3ST3B1,SH3PXD2B,MET,NRP1,ERRFI1,SMPDL3A,CKAP4,LRP12 |
| 1.502e-02 | -4.20 | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_DN | 178 | 27 | 17377 | 1707 |
GPT2,TNIK,SLC40A1,RNF144A,GJB2,OLAH,RAPGEF4,PRSS35,CBS,WNT11,SNAP25,TNKS1BP1,MBNL2,AMDHD1,FSTL5,GPR37,LGI2,EPCAM,EFEMP1,EPB41L3,BACH2,RGS10,MORN4,RNF122,ZNF365,ZNF385A,ABCG1 |
| 1.502e-02 | -4.20 | GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | MSigDB lists | GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | 178 | 27 | 17377 | 1707 |
ATF4,TMEM43,CRIM1,ITGA6,VLDLR,PPFIBP2,CBY1,CEBPA,VIM,GPSM2,SAV1,CENPV,ISG20,EPB41L3,SUGT1,IFT81,HLF,ICA1,KLF12,ALDOC,FAM114A2,RAP2A,PRKG1,TRIM3,IQGAP3,SLC1A5,SNX7 |
| 1.502e-02 | -4.20 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | 178 | 27 | 17377 | 1707 |
RGS16,MXI1,AASS,ATP8A1,FOXN3,BNIP3L,CBY1,CCNG1,PLEKHA1,FAM13A,GLCE,NELL2,EPB41L3,HLF,ZNF266,PDZD8,PRKCB,ABCA5,KIAA0355,CSF1,B3GALT2,BCL6,CAB39L,FHIT,ST8SIA1,SP140L,DUSP1 |
| 1.502e-02 | -4.20 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_DP_THYMOCYTE_UP | 178 | 27 | 17377 | 1707 |
CREB3L2,CD55,TUBA1A,CFH,RNF144A,GRB14,RBFOX2,XYLT1,MCTP2,SELL,VIM,GAS6,NHP2,PRKCA,EIF4EBP1,MAP9,OPN3,GSTM3,NEK11,TUFT1,RNF130,TNFSF4,RRAS2,ZNF460,SCN3A,CKAP4,STOM |
| 1.507e-02 | -4.20 | chr8q | MSigDB lists | chr8q | 6 | 3 | 17377 | 1707 |
GDAP1,SNAI2,RGS20 |
| 1.507e-02 | -4.20 | THUM_MIR21_TARGETS_HEART_DISEASE_DN | MSigDB lists | THUM_MIR21_TARGETS_HEART_DISEASE_DN | 6 | 3 | 17377 | 1707 |
ARHGAP26,EFEMP1,SLC7A1 |
| 1.508e-02 | -4.19 | phosphatase activity | molecular function | GO:0016791 | 272 | 38 | 17224 | 1680 |
INPPL1,DUSP8,PTPRD,UBASH3B,PTPN21,LPIN3,INPP1,EYA4,PPM1E,PLPP1,CDC14B,PALD1,FIG4,PPP2R2B,PTPRE,DUSP1,PFKFB4,PPP1R3D,SSH3,PFKFB2,PTPRU,PTPN6,PTPN13,DNAJC6,PLPP2,DUSP9,LHPP,PXYLP1,NT5DC2,PTPRC,PTPRJ,PLPPR2,DUSP19,INPP4B,PTPRN2,PTPRS,INPP5F,PSPH |
| 1.510e-02 | -4.19 | toxin metabolic process | biological process | GO:0009404 | 22 | 6 | 17256 | 1658 |
CBS,GSTO1,GSTO2,CTH,PAM,CYP1B1 |
| 1.510e-02 | -4.19 | chondrocyte development | biological process | GO:0002063 | 22 | 6 | 17256 | 1658 |
CHSY1,RUNX2,SERPINH1,BMPR2,SHOX2,COL27A1 |
| 1.510e-02 | -4.19 | positive regulation of myeloid leukocyte mediated immunity | biological process | GO:0002888 | 22 | 6 | 17256 | 1658 |
FGR,GATA2,STXBP1,SYK,VAMP8,GAB2 |
| 1.511e-02 | -4.19 | GO_MESODERM_DEVELOPMENT | MSigDB lists | GO_MESODERM_DEVELOPMENT | 114 | 19 | 17377 | 1707 |
EPB41L5,ACVR1,BMPR2,WLS,YAP1,WNT11,ACVR2B,ZFPM2,FGFR1,DKK1,SMAD3,IKZF3,EOMES,ITGB3,ITGA2,ACVR2A,BMPR1A,BMP4,SIX2 |
| 1.511e-02 | -4.19 | GO_SPECIFICATION_OF_SYMMETRY | MSigDB lists | GO_SPECIFICATION_OF_SYMMETRY | 114 | 19 | 17377 | 1707 |
MICAL2,NBL1,ACVR1,NKX3-2,ACVR2B,OVOL2,ARMC4,SMAD3,SETDB2,LRRC6,DYNC2LI1,ACVR2A,DISP1,DYNC2H1,BMP4,DNAH5,PCSK5,PCSK6,MEF2C |
| 1.511e-02 | -4.19 | ACTIVIN2R | prints domains | PR00653 | 6 | 3 | 4652 | 458 |
ACVR2A,ACVR2B,ACVR1 |
| 1.515e-02 | -4.19 | amino acid transmembrane transporter activity | molecular function | GO:0015171 | 84 | 15 | 17224 | 1680 |
SLC7A1,SERINC5,SLC3A2,SLC6A9,SLC7A11,SLC36A1,SERINC2,SLC7A5,SLC36A4,SLC6A15,SLC1A3,SLC7A2,SLC1A5,SLC16A10,SLC43A1 |
| 1.516e-02 | -4.19 | Apoptotic cleavage of cell adhesion proteins | REACTOME pathways | R-HSA-351906 | 11 | 4 | 10287 | 971 |
TJP1,DSP,DSG2,OCLN |
| 1.517e-02 | -4.19 | GO_B_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_B_CELL_RECEPTOR_SIGNALING_PATHWAY | 34 | 8 | 17377 | 1707 |
PTPRC,VAV3,PRKCB,NCKAP1L,PTPN6,PLEKHA1,SYK,MEF2C |
| 1.517e-02 | -4.19 | GO_RESPONSE_TO_FLUID_SHEAR_STRESS | MSigDB lists | GO_RESPONSE_TO_FLUID_SHEAR_STRESS | 34 | 8 | 17377 | 1707 |
ASS1,CA2,SMAD6,XBP1,PDGFRB,F3,NOS3,MEF2C |
| 1.517e-02 | -4.19 | GO_RESPONSE_TO_MONOAMINE | MSigDB lists | GO_RESPONSE_TO_MONOAMINE | 34 | 8 | 17377 | 1707 |
ID1,LRRK2,ADCY6,RYR2,PDE4D,PPARGC1A,ATP2B4,SNCA |
| 1.517e-02 | -4.19 | HAN_JNK_SINGALING_UP | MSigDB lists | HAN_JNK_SINGALING_UP | 34 | 8 | 17377 | 1707 |
EFNB2,TNK2,CXCL10,CD276,SGK1,SHOX2,CTNND2,DUSP1 |
| 1.517e-02 | -4.19 | GO_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | 34 | 8 | 17377 | 1707 |
IRS2,FOXP2,MYC,WNT11,BMP4,BMPR1A,SHOX2,FGFR1 |
| 1.517e-02 | -4.19 | GO_CAMP_METABOLIC_PROCESS | MSigDB lists | GO_CAMP_METABOLIC_PROCESS | 34 | 8 | 17377 | 1707 |
CALCRL,ADCY6,PDE8A,PDE4D,PDE1B,CACNB4,PDE10A,ADCY1 |
| 1.517e-02 | -4.19 | GO_CORECEPTOR_ACTIVITY | MSigDB lists | GO_CORECEPTOR_ACTIVITY | 34 | 8 | 17377 | 1707 |
TGFBR3,PTK7,ITGB3,ACVR2A,LRP6,ROR1,NRP1,GPC6 |
| 1.517e-02 | -4.19 | GO_CALCIUM_ION_REGULATED_EXOCYTOSIS | MSigDB lists | GO_CALCIUM_ION_REGULATED_EXOCYTOSIS | 76 | 14 | 17377 | 1707 |
DOC2A,TRIM9,UNC13B,SYT12,RAPGEF4,CADPS2,SNAP25,SYT14,SEPT5,PCLO,TC2N,RIMS2,SNPH,SCIN |
| 1.518e-02 | -4.19 | Gap junction | KEGG pathways | hsa04540 | 88 | 16 | 7161 | 730 |
TUBB4A,TUBA1A,PRKCB,ADCY1,PRKG1,ADRB1,ADCY6,PRKG2,TJP1,ITPR2,GUCY1A2,PRKCA,PLCB1,PDGFRB,PRKACB,GNAI1 |
| 1.518e-02 | -4.19 | Gap junction | KEGG pathways | ko04540 | 88 | 16 | 7161 | 730 |
TUBB4A,TUBA1A,PRKCB,ADCY1,PRKG1,ADRB1,ADCY6,PRKG2,TJP1,ITPR2,GUCY1A2,PRKCA,PLCB1,PDGFRB,PRKACB,GNAI1 |
| 1.520e-02 | -4.19 | GO_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_ORGANIC_HYDROXY_COMPOUND_BIOSYNTHETIC_PROCESS | 170 | 26 | 17377 | 1707 |
PLA2G4A,PRKAA2,MVK,SLC27A2,LPCAT2,MVD,CYB5R2,DHCR24,GATA3,ISYNA1,LPIN3,SNCA,CDS1,GPR37,CYP51A1,HMGCS1,IDI1,INSIG1,MSMO1,ACER2,PEMT,TRPC1,SQLE,PLTP,DHCR7,HMGCR |
| 1.520e-02 | -4.19 | GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | 170 | 26 | 17377 | 1707 |
UST,LATS2,MRC2,CFH,LGALS3,TSPAN15,GPR65,KLHL4,PTPN13,EPS8,RASD1,F12,CHSY1,NPDC1,FAM110B,CAMK2N1,ICA1,ZFYVE28,C1orf53,PLEKHG1,MARCKS,ST8SIA1,ATG5,BTRC,STOM,IGFBP3 |
| 1.520e-02 | -4.19 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP | 170 | 26 | 17377 | 1707 |
CXCR5,MXI1,ZNF395,CKAP2,ST6GAL1,ARID5B,SETBP1,COBLL1,ADD2,SKAP1,SEL1L3,RNF141,CD37,ABLIM1,IKZF3,BACH2,PRKCB,BACE2,KMO,MYC,PIK3C2B,SP140,PTPRCAP,RRAS2,RASGRP1,PKIA |
| 1.521e-02 | -4.19 | KIM_MYCN_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYCN_AMPLIFICATION_TARGETS_DN | 91 | 16 | 17377 | 1707 |
EPB41L5,GCA,INPPL1,TTC39B,FN1,PLEKHA5,ILDR2,PPP2R3A,ZNF93,CPNE2,ZDHHC23,PLEKHG1,FAM107B,MORN2,KLF5,NKX2-1 |
| 1.523e-02 | -4.18 | positive regulation of cell death | biological process | GO:0010942 | 684 | 83 | 17256 | 1658 |
GRIK2,COL18A1,LILRB1,NTRK3,TIAM2,F3,SCIN,GSDME,TLR3,RPS6KA2,UNC13B,PMAIP1,KMO,BCL6,DAB2IP,HRK,TLR4,FANK1,SLIT2,PDGFRB,IGFBP3,CYP1B1,ATF4,GAPDH,COL4A3,ACVR1C,LRRK2,BNIP3L,PREX1,ATF3,WNT11,CD40,SAV1,ARHGEF26,SNCA,SMAD3,GSN,BEX3,RASGRF2,HPGD,BBC3,TNFSF15,PPARGC1A,MEF2C,EFNB2,LATS2,ARHGEF11,ITGA6,APBB1,BIK,TPD52L1,DDIT4,MCF2L,MYC,PRKCD,PRELID1,TFAP2A,BNIP3,PNMA2,DUSP1,HMGCR,RPL26,VAV3,ATP5IF1,UNC5C,MSX1,RAPGEF2,HIP1,OBSCN,RACK1,TLR6,FAM162A,GPLD1,DKK1,ID3,NACC2,ACER2,MAP2K6,BMP4,MAP3K20,SFN,FOXA1,DDIT3 |
| 1.524e-02 | -4.18 | GO_MUSCLE_CONTRACTION | MSigDB lists | GO_MUSCLE_CONTRACTION | 228 | 33 | 17377 | 1707 |
SCN5A,SORBS1,ARHGEF11,PKP2,CHUK,SORBS3,EEF2,SCN1B,CACNB2,SMTN,ACTA2,PDE4D,NEB,CHRM3,PXN,ANK2,FGF12,RYR2,VIM,ATP1B1,SNTB1,ASPH,GJC1,HTR7,GNAO1,MAP2K6,ALDOA,TMOD2,MYOM2,OXTR,TPM1,CACNA2D1,ATP1A3 |
| 1.525e-02 | -4.18 | GO_REGULATION_OF_PROTEIN_SECRETION | MSigDB lists | GO_REGULATION_OF_PROTEIN_SECRETION | 374 | 50 | 17377 | 1707 |
EXPH5,FN1,C1QTNF3,LGR4,STXBP5L,TRIM16,CD276,APBB1,ARL2,GATA3,LILRB1,ABAT,GAS6,ITPR2,NRXN1,PRKCA,BMP6,MCU,NKX6-1,RAB11FIP5,KCNS3,SREBF1,MARCKS,TLR4,MYRIP,SYK,RASGRP1,HMGCR,VEGFC,TRPM4,PFKFB2,ACVR1C,CACNA1E,WLS,RAPGEF4,SYBU,PRKCQ,SNAP25,CD40,TLR6,SERGEF,GPLD1,IRS2,FGR,ICA1,GBP1,XBP1,PAM,ATG5,TNFSF4 |
| 1.527e-02 | -4.18 | TEAD1 (TEA domain transcription factor 1) | protein interactions | 7003 | 27 | 7 | 17029 | 1718 |
MEF2B,YAP1,VGLL4,GCAT,WWTR1,MEF2C,SKI |
| 1.527e-02 | -4.18 | OPRD1 (opioid receptor delta 1) | protein interactions | 4985 | 27 | 7 | 17029 | 1718 |
CANX,PRKCA,KLHL3,WLS,GNAO1,PRKCD,GNAI1 |
| 1.528e-02 | -4.18 | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | MSigDB lists | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | 296 | 41 | 17377 | 1707 |
CREB3L2,MYCBP2,LATS2,ELOVL4,ROBO2,BMPR2,MYO1B,RHPN2,GPR180,CEBPA,NOVA1,FAM110B,FOXG1,RNF141,RGS17,CNTN4,EOMES,FRY,GRHL1,PIK3AP1,GATA2,TACC2,DAB2IP,SMAD6,SCN3A,DPP10,MARK1,PRDM13,NFIA,FHL2,PLEKHA1,ARRDC4,RNF44,BCL11A,ZNF711,INSIG1,FCHO2,FBN1,RBPMS2,TECPR2,DOCK9 |
| 1.530e-02 | -4.18 | HAVCR2 (hepatitis A virus cellular receptor 2) | protein interactions | 84868 | 67 | 13 | 17029 | 1718 |
EXPH5,MYO1D,MYADM,TCAF2,LGR4,PKN3,SLC22A18,CNKSR3,MAP3K21,ACVR2A,PKP2,BMPR1A,IL1RAP |
| 1.531e-02 | -4.18 | nucleobase-containing small molecule biosynthetic process | biological process | GO:0034404 | 149 | 23 | 17256 | 1658 |
NUDT10,ADAL,GAPDH,PDE1B,PNP,ENO2,PFKFB2,OGDHL,PDE8A,NUDT12,TYMP,ENPP1,PRTFDC1,PDE10A,ALDOC,ALDOA,HK2,PGM2L1,HK1,PDE4D,ENO1,SMPDL3A,NUDT17 |
| 1.531e-02 | -4.18 | GGGCGGR_V$SP1_Q6 | MSigDB lists | GGGCGGR_V$SP1_Q6 | 2741 | 301 | 17377 | 1707 |
ARHGAP26,CGN,PPP4R4,LANCL3,FLVCR2,PRSS12,RECK,GATA3,NPM1,ENAH,CEBPA,STAT5B,CADM2,BCAN,EYA4,SLC9A7,TRPS1,IKZF5,SLC16A2,PPFIA2,CHRDL1,KCNS3,ATRNL1,TMED9,COG3,PPP2R2B,PLTP,THSD1,GLDC,NKX2-1,MEIS2,DEPTOR,SLC25A28,ACVR2B,FGF17,KCND3,GPC6,SLC7A1,ENTPD7,PLK2,ADRB1,SERPINI1,UNC5B,MEF2C,LRFN5,INPPL1,ITGA6,TJP1,DYNC1I1,HPCAL4,ADCK1,MYC,RUNDC3B,LMAN2,NCAM1,STXBP1,GFRA1,RPS23,PTCH2,EPB41L5,BDNF,PLEKHA8,MGST3,RAPGEF4,HIP1,NPC2,ARRDC4,PLCB1,DAGLA,PKN3,PMEPA1,C1orf21,MPP2,HOXD13,FBXO27,CDH2,NUDT10,PCSK1N,RASAL2,RGS20,IL13RA1,GRK6,ZNF827,TMEM53,NELL2,ASNS,MARCKS,DZANK1,GAPDH,RNF145,TMEM43,PFKFB2,FZD4,NPM3,WNT11,ATF3,ATP1B1,DSP,FGFR1,METAP1D,SNCA,GABARAPL1,HTR7,IRS2,GYPC,PRKCB,RCN3,P4HA1,HPGD,KLF5,HS3ST3B1,DBP,ATG5,HOXB9,NR3C2,ANKRD13B,FZD8,GPR180,PHLDA2,TSPAN17,COL27A1,RGS17,HMGCS1,GPR155,PCBP4,SGK3,SLC6A15,SMAD6,ZFP36L2,PFKFB4,MN1,PDLIM7,TRPM4,SLC40A1,ALDH2,CTTNBP2NL,HOXA1,ZIC1,CEBPB,RPL12,SRD5A3,SLCO5A1,BMP4,BTRC,TLL2,TPT1,SLC43A1,EXPH5,CACNG3,UGDH,NDRG2,MGAT5B,ABAT,ITPR2,IKZF2,SLCO3A1,FSTL5,FKBP11,PLS3,CYP51A1,RND2,RTN1,FKBP9,RUFY4,KCNN2,TRPC1,EPHB6,TMEM132E,ETV1,PRKACB,ATL1,SESN2,CD55,PNRC1,SKAP2,CAPN5,NFE2L1,BATF,RNF44,SESN1,PLEKHB1,TSKU,DYRK1B,ITGBL1,TIGD4,MLLT3,FRMD5,PCSK5,HS6ST3,UST,KCNV1,BCL11B,RGS16,ZCCHC24,NUMBL,IGF1R,SMTN,FBXL2,PAK1,NDUFA4L2,PCDH10,SLC27A2,MGAT4B,EFNA3,EDEM3,TCEA3,MAFB,WWC1,OBSCN,SLITRK5,SDK1,SLC2A6,RAB31,NXPH4,NKX2-8,PANK3,CELSR3,AKAP5,BCL6B,RNF24,NTRK3,TDRKH,CANX,SEZ6L2,PRR7,TNKS1BP1,SEMA6A,SP8,ZNF362,KCTD15,UNC13B,REEP1,BCL6,MAP7,ACVR2A,STEAP3,PROS1,FHIT,TMEM56,SEMA6C,GLI1,SUSD3,TUBA1A,PTPN6,MVD,PRDM13,FGF12,VIM,FBXO36,CD40,BCL11A,BATF3,SMAD3,KPNA3,BACH2,MAOA,CNTN1,COL9A3,BMPR2,ENO2,REL,APBB1,BLVRB,CLSTN2,FAM117B,PRDM8,COL4A5,NOTUM,OVOL2,MCU,RAB11FIP5,MAP1A,DSG2,EIF1,STC2,SGK1,MARCH3,TSPAN13,PCK2,FKBP14,DUSP1,MOB1B,PPP1R3D,NR4A1,OGDHL,PRICKLE1,AGAP2,ZFPM2,TGDS,GALNT14,NPDC1,LRAT,LEPR,MAP1B,GPR37,DEXI,SUGT1,ICA1,MYADM,PRCP,KIF1B |
| 1.533e-02 | -4.18 | GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSMEMBRANE_TRANSPORT | 122 | 20 | 17377 | 1707 |
GSTM2,LGALS3,ANK2,RYR2,GSTO1,AMIGO1,ATP1B1,ASPH,NOS1AP,SNCA,CXCL10,CA2,AKAP7,CACNB2,TRPC1,BMP4,HSPA2,TESC,CACNA2D1,PDGFRB |
| 1.537e-02 | -4.18 | GO_NUCLEAR_OUTER_MEMBRANE_ENDOPLASMIC_RETICULUM_MEMBRANE_NETWORK | MSigDB lists | GO_NUCLEAR_OUTER_MEMBRANE_ENDOPLASMIC_RETICULUM_MEMBRANE_NETWORK | 936 | 112 | 17377 | 1707 |
CREB3L2,PLA2G4A,ACSL1,ELOVL4,LPCAT2,DNAJC3,XYLT1,ITPR2,SEZ6L2,LPIN3,CANX,ABHD4,CYP26A1,NOS1AP,FKBP11,CDS1,CYP51A1,RTN1,FKBP9,TLR3,SEC16B,ZDHHC6,REEP1,TMED9,PROS1,RASGRP1,ALG10B,CYP1B1,ATL1,ANTXR2,TMEM67,ERGIC1,EBPL,LRRC8B,TGFA,WLS,CYB5R2,C3orf52,JPH1,TRAM1L1,LRMP,NFE2L1,ASPH,ATP10D,SNCA,GJC1,INSIG1,RASGRF2,PEMT,WFS1,ERN1,ALG11,CYP2U1,MBOAT2,NR3C2,TYRO3,ALOX5AP,CLGN,SEC24D,CYP2J2,ELOVL7,DHCR24,CYP4V2,UBAC2,CLSTN2,SCD,SPINK5,PGAP1,RNF180,GALNT1,BNIP1,SOAT2,MSMO1,FLRT3,SREBF1,SGK1,LMAN2,CERS4,NCEH1,MOXD1,FAR2,FKBP14,CKAP4,HMGCR,FADS1,SLC37A1,SLC27A2,RNF170,MGST3,AGPAT4,ELOVL3,GPSM1,RYR2,SHISA2,ARHGAP32,ILDR2,LRAT,HERPUD1,GPR37,PLOD2,FMO4,MFSD2A,OSBPL5,XBP1,SRD5A3,SQLE,PLD1,CERS1,DHCR7,PTGES,OSBPL6,ABCG1 |
| 1.539e-02 | -4.17 | FCGRT (Fc fragment of IgG receptor and transporter) | protein interactions | 2217 | 60 | 12 | 17029 | 1718 |
FGFR4,PCDH10,PODXL2,LRP4,C3orf52,LDLR,DUSP9,LRP6,PTPRS,DYNC2H1,FGFR1,PCDH7 |
| 1.542e-02 | -4.17 | EGF_2 | pfam domains | PF07974 | 16 | 5 | 17054 | 1666 |
ATRNL1,EGFL7,ITGB7,ITGBL1,ITGB3 |
| 1.542e-02 | -4.17 | Kringle | pfam domains | PF00051 | 16 | 5 | 17054 | 1666 |
HGF,F12,ROR1,PRSS12,KREMEN1 |
| 1.546e-02 | -4.17 | MULLIGHAN_NPM1_SIGNATURE_3_DN | MSigDB lists | MULLIGHAN_NPM1_SIGNATURE_3_DN | 154 | 24 | 17377 | 1707 |
TRPM4,PRAME,NBL1,ST14,ATP9A,LRP4,LDLR,CD7,COL14A1,DENND3,FGFR1,FHOD3,RERE,HEG1,RPL28,PMAIP1,SCRN1,SVIL,HGF,RPL4,PDE4D,RNF130,PCSK6,ABCG1 |
| 1.546e-02 | -4.17 | GSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP | MSigDB lists | GSE9946_IMMATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP | 130 | 21 | 17377 | 1707 |
SV2B,PLBD2,CCDC148,TCP11L2,PTPRU,ITGA6,MCTP2,BEGAIN,AMIGO1,DSP,NRG3,TGFBR3,PCDHB7,ISM1,FAM114A2,MATN2,HS3ST5,NIPAL2,FILIP1,OCLN,PNMA2 |
| 1.547e-02 | -4.17 | ITGB1 (integrin subunit beta 1) | protein interactions | 3688 | 119 | 20 | 17029 | 1718 |
SLC3A2,PXN,TUBA1A,TCTN2,LGALS3,FN1,MYO10,DSTN,ITGA6,EPS8,TNFSF13B,FHL2,YAP1,RACK1,PRKCA,CANX,CDS1,IGF1R,ITGA2,ITGB3 |
| 1.552e-02 | -4.17 | GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 146 | 23 | 17377 | 1707 |
CREB3L2,BCL11B,FARP1,GCNT2,CELSR1,SEC24D,TES,PRKCQ,BATF,CD40,ATP10D,CCDC120,IDI1,TMEM154,IGF1R,KLF12,GRHL1,REEP1,EBF4,ST8SIA1,TNFRSF17,IL1RAP,SMPDL3A |
| 1.556e-02 | -4.16 | establishment of synaptic vesicle localization | biological process | GO:0097480 | 101 | 17 | 17256 | 1658 |
DOC2A,DNM3,SYT12,KIF5A,KIF5C,SNAP25,SYT14,PCLO,SNCA,TRIM9,UNC13B,LIN7A,CADPS2,SEPT5,TC2N,RIMS2,SNPH |
| 1.556e-02 | -4.16 | glycosaminoglycan biosynthetic process | biological process | GO:0006024 | 101 | 17 | 17256 | 1658 |
UST,CHSY3,GCNT2,XYLT1,UGDH,SDC3,PXYLP1,CHSY1,BCAN,GPC6,GLCE,HS3ST5,DSEL,HS3ST3B1,PDGFRB,B4GALT7,B4GALT6 |
| 1.556e-02 | -4.16 | synaptic vesicle transport | biological process | GO:0048489 | 101 | 17 | 17256 | 1658 |
DOC2A,DNM3,SYT12,KIF5A,KIF5C,SNAP25,SYT14,PCLO,SNCA,TRIM9,UNC13B,LIN7A,CADPS2,SEPT5,TC2N,RIMS2,SNPH |
| 1.556e-02 | -4.16 | fat cell differentiation | biological process | GO:0045444 | 101 | 17 | 17256 | 1658 |
ZNF516,C1QTNF3,NR4A1,ITGA6,ARID5B,CTBP2,CEBPA,CBY1,PLCB1,BBS9,CEBPB,ADRB1,SREBF1,BNIP3,PPARGC1A,SMAD6,TMEM120B |
| 1.557e-02 | -4.16 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 195 | 29 | 17377 | 1707 |
CARS,RHOQ,SKAP2,LGALS3,GPR65,MVD,UGDH,ARL2,SCD,TGDS,ADSSL1,IL18R1,FAM162A,HERPUD1,DDIT4,HOPX,CYP51A1,MAPKAPK2,TRIB3,IDI1,SEMA4F,SLC30A4,MSMO1,HK2,SQLE,DHCR7,AGL,MLLT3,HMGCR |
| 1.557e-02 | -4.16 | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN | MSigDB lists | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN | 195 | 29 | 17377 | 1707 |
VAV3,SYNPO2,SH3BP2,PNRC1,IL15,GPR65,AGPAT4,SPATA13,CALCRL,NOTUM,PRDM1,CTTNBP2NL,SLC7A2,ATP11A,BATF,UBTD2,CA13,PCDH7,RASSF8,SUGT1,RPS6KA2,IDI1,SETDB2,GRHL1,NCOA7,MARCKS,TMEM120B,SYK,RAPGEF5 |
| 1.557e-02 | -4.16 | GSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_DN | 195 | 29 | 17377 | 1707 |
FADS1,TYRO3,MVK,B3GALT1,FZD4,REL,CD276,DHCR24,EFNA3,FEZ1,CEBPA,ATOH1,ATP1B1,ZFPM2,RNF44,CA8,PFN2,GPR19,GABARAPL1,ATP7B,FHIT,SPRY4,POU2F2,ARL4D,PTPRE,MAPK10,SCN3A,CKAP4,CACNA2D1 |
| 1.558e-02 | -4.16 | Kringle | interpro domains | IPR000001 | 16 | 5 | 18492 | 1811 |
HGF,ROR1,F12,PRSS12,KREMEN1 |
| 1.558e-02 | -4.16 | EGF_extracell | interpro domains | IPR013111 | 16 | 5 | 18492 | 1811 |
ATRNL1,EGFL7,ITGB7,ITGBL1,ITGB3 |
| 1.558e-02 | -4.16 | Kringle_sf | interpro domains | IPR038178 | 16 | 5 | 18492 | 1811 |
HGF,ROR1,F12,PRSS12,KREMEN1 |
| 1.558e-02 | -4.16 | Kringle_CS | interpro domains | IPR018056 | 16 | 5 | 18492 | 1811 |
HGF,ROR1,F12,PRSS12,KREMEN1 |
| 1.560e-02 | -4.16 | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | 220 | 32 | 17377 | 1707 |
FN1,PSTPIP2,UBASH3B,ITGA6,OLAH,ADAMTS6,SLC7A2,EPHB1,SPIRE1,ZBTB38,CA2,PDE4D,POU2F2,ANTXR2,PXN,RAB3B,CD55,TMEM65,CAPN5,ELMOD1,HIP1,WWC1,PRDM1,JAM3,DKK1,HOMER3,ADAMTS17,RBPMS2,PTPRN2,MAOA,GEM,RRAGD |
| 1.560e-02 | -4.16 | UDAYAKUMAR_MED1_TARGETS_DN | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_DN | 220 | 32 | 17377 | 1707 |
INPPL1,ZNF395,RHOBTB1,ST6GAL1,DDR1,DENND3,GDPD5,BMP6,PCDH7,SMTN,SNAI2,CTH,MN1,MSX1,ARID5B,NFE2L1,ATF3,SNAP25,PALLD,INTS6,RNF44,DKK1,GABARAPL1,MAPKAPK2,GSN,SH3GL2,PLK2,P4HA2,TUFT1,TPM1,LIFR,HEY1 |
| 1.561e-02 | -4.16 | extracellular structure organization | biological process | GO:0043062 | 356 | 47 | 17256 | 1658 |
MPZL3,COL9A3,FN1,RECK,ITGA6,COL18A1,LAMC3,COL4A5,GAS6,BCAN,COL14A1,SPINK5,DDR1,COL27A1,SOAT2,ABCA5,ABI3BP,ERO1B,ITGB3,COL19A1,LOXL4,SH3PXD2B,SERPINH1,JAM2,PLTP,COL9A2,PRKACB,CYP1B1,ITGB7,COL6A2,COL4A3,COL4A4,THSD4,JAM3,MMP15,GSN,FBN1,ADAMTS3,THBS4,CTSV,LAMB1,ITGA2,BMP1,P4HA1,MMP16,ABCG1,TLL2 |
| 1.577e-02 | -4.15 | LEIN_CHOROID_PLEXUS_MARKERS | MSigDB lists | LEIN_CHOROID_PLEXUS_MARKERS | 99 | 17 | 17377 | 1707 |
FADS1,FHAD1,COL9A3,MSX1,TMEM237,CFH,FZD4,ELOVL7,NEK11,CAB39L,PCOLCE2,TBC1D9,PLTP,STEAP1,LEPR,PERP,CSRP2 |
| 1.578e-02 | -4.15 | GHO_ATF5_TARGETS_DN | MSigDB lists | GHO_ATF5_TARGETS_DN | 16 | 5 | 17377 | 1707 |
TMED9,ID1,RND3,ITGA2,DUSP1 |
| 1.578e-02 | -4.15 | chr4q26 | MSigDB lists | chr4q26 | 16 | 5 | 17377 | 1707 |
SYNPO2,UGT8,ALPK1,SEC24D,TRAM1L1 |
| 1.578e-02 | -4.15 | NIELSEN_SCHWANNOMA_UP | MSigDB lists | NIELSEN_SCHWANNOMA_UP | 16 | 5 | 17377 | 1707 |
NLGN4X,NRXN1,ST14,PLEKHB1,NKX2-1 |
| 1.578e-02 | -4.15 | AGCGCTT,MIR-518F,MIR-518E,MIR-518A | MSigDB lists | AGCGCTT,MIR-518F,MIR-518E,MIR-518A | 16 | 5 | 17377 | 1707 |
NRXN1,PTPRU,MCF2L,CPEB1,ZNF385A |
| 1.578e-02 | -4.15 | GO_RESPONSE_TO_EPINEPHRINE | MSigDB lists | GO_RESPONSE_TO_EPINEPHRINE | 16 | 5 | 17377 | 1707 |
RYR2,PDE4D,PPARGC1A,ATP2B4,SNCA |
| 1.578e-02 | -4.15 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_NH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR | 16 | 5 | 17377 | 1707 |
AASS,ALDH1L2,BLVRB,ALDH1L1,PYCR1 |
| 1.578e-02 | -4.15 | GO_PROTEIN_BINDING_INVOLVED_IN_CELL_ADHESION | MSigDB lists | GO_PROTEIN_BINDING_INVOLVED_IN_CELL_ADHESION | 16 | 5 | 17377 | 1707 |
PKP2,EPCAM,DSP,DSG2,ITGA2 |
| 1.578e-02 | -4.15 | LEE_INTRATHYMIC_T_PROGENITOR | MSigDB lists | LEE_INTRATHYMIC_T_PROGENITOR | 16 | 5 | 17377 | 1707 |
GXYLT2,SKAP2,TNFSF4,RRAS2,ATP6AP1L |
| 1.578e-02 | -4.15 | KYNG_NORMAL_AGING_UP | MSigDB lists | KYNG_NORMAL_AGING_UP | 16 | 5 | 17377 | 1707 |
PMEPA1,MBNL2,RHOD,C15orf41,ITGA2 |
| 1.578e-02 | -4.15 | skeletal muscle tissue development | biological process | GO:0007519 | 125 | 20 | 17256 | 1658 |
BVES,ATF3,DNER,MYORG,SKI,FOXP2,MSC,HLF,EOMES,RIPOR2,POPDC3,KCNAB1,EEF2,HEYL,COL19A1,SVIL,KLF5,MYH15,MYOM2,MEF2C |
| 1.578e-02 | -4.15 | regulation of cardiac muscle contraction | biological process | GO:0055117 | 78 | 14 | 17256 | 1658 |
TRPM4,SCN5A,GSTM2,FGF13,ANK2,DSG2,EHD3,RYR2,PKP2,GSTO1,ATP1B1,PDE4D,DSP,NOS1AP |
| 1.578e-02 | -4.15 | WNT_subtype | COSMIC cancer mutations | WNT_subtype | 188 | 28 | 17385 | 1698 |
ARHGAP26,CARS,VAV3,RASAL2,DCC,EPS8,EDEM3,GRID1,CCDC85A,WDFY4,FAM13A,GUCY1A2,MAGI3,NEGR1,LMLN,BACH2,TERT,MAP7,CLMN,NBEA,DLG2,PPP2R2B,NRP1,MAGI2,TBC1D4,IL1RAP,XKR4,FRMD5 |
| 1.579e-02 | -4.15 | DELPUECH_FOXO3_TARGETS_UP | MSigDB lists | DELPUECH_FOXO3_TARGETS_UP | 69 | 13 | 17377 | 1707 |
GSN,MXI1,CD55,IGF1R,IGFBP6,TGFA,BCL6,HPGD,KLF5,SEMA3C,PHLDA2,SMPDL3A,RERE |
| 1.579e-02 | -4.15 | GO_PHOSPHATIDYLINOSITOL_BISPHOSPHATE_BINDING | MSigDB lists | GO_PHOSPHATIDYLINOSITOL_BISPHOSPHATE_BINDING | 69 | 13 | 17377 | 1707 |
MARK1,FCHO2,PLEKHA5,STXBP6,MYO1B,PLEKHA1,SH3PXD2B,CLVS2,APBA1,PFN2,PLCB1,SCIN,GAB2 |
| 1.579e-02 | -4.15 | DOANE_BREAST_CANCER_CLASSES_UP | MSigDB lists | DOANE_BREAST_CANCER_CLASSES_UP | 69 | 13 | 17377 | 1707 |
FGFR4,TNIK,SIDT1,KMO,SLC16A2,GALNT6,XBP1,FASN,TRIM3,CERS4,TBC1D9,FAM174B,FOXA1 |
| 1.579e-02 | -4.15 | PID_MTOR_4PATHWAY | MSigDB lists | PID_MTOR_4PATHWAY | 69 | 13 | 17377 | 1707 |
PXN,EEF2,EIF4EBP1,DEPTOR,SREBF1,SGK1,BNIP3,PLD1,PRKCA,PPARGC1A,SFN,DDIT4,RRAGD |
| 1.582e-02 | -4.15 | bZIP_1 | pfam domains | PF00170 | 28 | 7 | 17054 | 1666 |
CREB3L2,ATF3,ATF4,CREB5,BATF,JDP2,BATF3 |
| 1.582e-02 | -4.15 | extracellular matrix organization | biological process | GO:0030198 | 312 | 42 | 17256 | 1658 |
MPZL3,COL9A3,FN1,RECK,ITGA6,COL18A1,LAMC3,COL4A5,GAS6,BCAN,COL14A1,SPINK5,DDR1,COL27A1,ABI3BP,ERO1B,ITGB3,COL19A1,LOXL4,SH3PXD2B,SERPINH1,JAM2,COL9A2,CYP1B1,ITGB7,COL6A2,COL4A3,COL4A4,THSD4,JAM3,MMP15,GSN,FBN1,ADAMTS3,THBS4,CTSV,LAMB1,ITGA2,BMP1,P4HA1,MMP16,TLL2 |
| 1.582e-02 | -4.15 | negative regulation of transferase activity | biological process | GO:0051348 | 312 | 42 | 17256 | 1658 |
PRKN,LATS2,DUSP8,UBASH3B,DNAJC3,IPO5,NPM1,CEBPA,PKN1,PPM1E,IGF1R,ZFYVE28,FLRT3,PRKCD,LRP6,DAB2IP,ERRFI1,SPRY2,HMGCR,DUSP1,MSTN,PTPN6,DEPTOR,PREX1,DUSP9,PRKAR2B,RACK1,WARS,CAMK2N1,IRS2,PTPRC,TRIB3,PTPRJ,WWTR1,DUSP19,BMP4,SPRY4,CERS1,TESC,SMYD3,PKIA,SFN |
| 1.582e-02 | -4.15 | SHC1 (SHC adaptor protein 1) | protein interactions | 6464 | 264 | 38 | 17029 | 1718 |
MYO1D,INPPL1,RASAL2,PSTPIP2,UBASH3B,EPS8,NPM1,STAT5B,NTRK3,LCP2,PRKCA,DDR1,PLS3,IGF1R,PRKCD,ITGB3,GHR,ERRFI1,MET,STXBP1,SYK,PDGFRB,GAB2,PAK1,VAV3,TUBA1A,PTPN6,FASN,GAREM1,ARHGAP32,PEAK1,FGFR1,IRS2,MAPKAPK2,PIK3C2B,LRRK1,MME,PSPH |
| 1.584e-02 | -4.15 | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP | MSigDB lists | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP | 187 | 28 | 17377 | 1707 |
MN1,MOCOS,SLC3A2,DYRK3,CELSR1,TUBA1A,DUSP8,GCAT,RAPGEF2,MLF1,LITAF,ST6GALNAC3,LACC1,LCP2,CYP51A1,CEBPB,ENPP1,ASNS,PMEPA1,CDC14B,EHD3,NCOA7,RGS10,CDH17,HSPA2,RAPGEF5,DOCK8,DUSP1 |
| 1.584e-02 | -4.15 | GSE16266_CTRL_VS_LPS_STIM_MEF_DN | MSigDB lists | GSE16266_CTRL_VS_LPS_STIM_MEF_DN | 187 | 28 | 17377 | 1707 |
SH3BP2,SMAD9,FZD4,SELL,PKP2,CBS,CR2,SCD,RARRES2,CD40,ZDHHC14,SESN1,BBS9,GPLD1,DCBLD2,BCL11A,EBF1,KMO,MGAT1,COL25A1,GHR,CMPK2,MAGI2,NKX2-8,TSPAN9,LIFR,FOXA1,PCSK6 |
| 1.584e-02 | -4.15 | GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP | MSigDB lists | GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP | 187 | 28 | 17377 | 1707 |
LONRF1,PHLDB2,SLC40A1,PXN,KDM5B,IL15,DOCK1,RECK,GALNT6,UGDH,HOMER2,CYP4V2,TJP1,FAM117B,TMEM170B,FNDC3A,ADSSL1,IKZF2,RAB11FIP5,GPR160,CLDN12,TECPR2,ZNF704,PAM,CNNM2,GSTM3,GFI1,CKAP4 |
| 1.584e-02 | -4.15 | GSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN | MSigDB lists | GSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN | 187 | 28 | 17377 | 1707 |
ANTXR2,PLSCR4,GALNT12,SOX21,ZCCHC24,DEPTOR,CYP4V2,TMTC4,PRRG1,PSD3,FAM117B,FAM198B,MFSD6,TTC28,PGAP1,HERPUD1,ZNF362,TM9SF2,CDC14B,ALDOC,C1orf21,SVIL,SQLE,TUFT1,LRP6,PROS1,TBC1D4,MEF2C |
| 1.584e-02 | -4.15 | GSE2826_WT_VS_XID_BCELL_DN | MSigDB lists | GSE2826_WT_VS_XID_BCELL_DN | 187 | 28 | 17377 | 1707 |
KDM5B,IGFBP6,NR6A1,RECK,DSTN,PLEKHA5,HEBP1,F12,ATP1B1,DOCK5,GRPEL2,FHOD3,GLCE,MAPKAPK2,GALNT3,BEX4,NAV1,INSIG1,ENTPD7,P4HA2,ADCY6,COL19A1,TMEM37,SLC1A5,TSHR,GATM,PTGES,SIX2 |
| 1.584e-02 | -4.15 | GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 187 | 28 | 17377 | 1707 |
EFNB2,MSX1,SORBS1,AASS,WLS,UGDH,ACO1,ZIC2,ITPR2,ATP11A,CANX,GDPD5,PHLDA2,DDIT4,DYRK1B,AK1,IGF1R,SOAT2,LRRC6,DLX6,PLK2,MATN2,WWTR1,HK2,HPGD,KLF5,ABCG1,B4GALT6 |
| 1.584e-02 | -4.15 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_DN | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_DN | 187 | 28 | 17377 | 1707 |
ARHGAP26,CCDC126,INPPL1,FARP1,GCAT,SH2D2A,SEC24D,RHOD,PTPN13,TMEM126A,LITAF,TMTC4,TTYH2,COBLL1,PLS1,SHISA2,ISYNA1,PHGDH,ABHD4,IKZF2,GDPD5,GABARAPL1,LGI2,PTPRJ,SLC22A15,MYO6,NRP1,SPRY2 |
| 1.584e-02 | -4.15 | GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_UP | MSigDB lists | GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_UP | 187 | 28 | 17377 | 1707 |
CREB3L2,TYRO3,GNG12,TUBA1A,CAP2,MGAT4B,ACO1,ADD2,COTL1,GRK6,GPSM2,CDC42BPA,PALLD,PRKCA,NT5DC2,EML1,ABLIM1,SEMA4F,SLC7A11,PDLIM3,UNC13B,AHNAK2,SMTN,ARHGAP28,OXTR,PERP,IGSF3,CNTN1 |
| 1.584e-02 | -4.15 | GSE557_CIITA_KO_VS_I_AB_KO_DC_UP | MSigDB lists | GSE557_CIITA_KO_VS_I_AB_KO_DC_UP | 187 | 28 | 17377 | 1707 |
QSOX1,CARD6,DNM3,PXN,EBPL,RECK,RAPGEF4,LITAF,NPC2,BATF,CD40,ZDHHC14,BBS9,SLC46A3,KBTBD11,FKBP11,BATF3,HOPX,ICA1,TRIM34,KLF12,PMEPA1,AKAP7,MARCKS,POU2F2,CKAP4,SLC43A1,NUDT17 |
| 1.584e-02 | -4.15 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_DN | 187 | 28 | 17377 | 1707 |
ZNF516,ALOX5AP,ARID5B,SSX1,HERC5,BATF,HERC6,LEPR,RERE,F3,ISG20,MTUS1,MSC,BAG3,RPL28,GBP1,CSF1,AFF2,ATRNL1,NEK11,SFMBT1,JAKMIP2,TOX,SP140,IPCEF1,PTPRCAP,STOM,DOCK9 |
| 1.584e-02 | -4.15 | GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 1425 | 164 | 17377 | 1707 |
ACVR1,ACSL1,FGF13,DNAJC3,GATA3,NPM1,CEBPA,STAT5B,PRKCA,SNX9,NOS1AP,F3,PMAIP1,ITGB3,RAP2A,PCOLCE2,TLR4,RASGRP1,PRKACB,PDGFRB,TNK2,GCNT2,COL4A3,ACVR1C,TGFA,LRRK2,PRKAR2B,ACVR2B,F12,INHBC,GSN,GPRC5B,NCKAP1L,CCBE1,PLK2,ERN1,TNFRSF1A,BMP1,BBC3,DIRAS1,NRP1,PPARGC1A,MAGI2,MEF2C,FN1,FBXO4,JDP2,SORBS3,TNFRSF19,PFN2,RNF180,EEF2,MYC,PRELID1,SREBF1,ADCY6,PRR16,HMGCR,FGFR4,PAK1,DISC1,MSTN,VLDLR,PACSIN3,DUSP9,WWC1,STRADB,HIP1,ARRDC4,PLCB1,FAM162A,CPEB1,HERPUD1,MAPKAPK2,PELI2,THBS4,CSF1,INHBE,CDH2,SMYD3,NEK10,AVPI1,IL15,AKAP5,RNF144A,NTRK3,LCP2,PIBF1,PPP1R9A,TLR3,CDC14B,DACT1,BCL6,ACVR2A,DAB2IP,MARCKS,HSPA2,PERP,SNAI2,FZD1,IGFBP3,FZD4,ADCY1,RNF125,WNT11,PRKCQ,RARRES2,CD40,ASPH,C4BPB,FGFR1,SNCA,SMAD3,NRG3,RNF217,WFS1,PEMT,ITGA2,DUSP19,TNFSF15,HGF,BMPR1A,MAPK10,MID1,CNTN1,TNIK,EDA2R,BMPR2,FZD8,CD276,LRP4,P2RY1,GAS6,PKN1,NDFIP2,TPD52L1,BMP6,PPP2R3A,NEDD4,RASD2,GHR,PRKCD,AFAP1L2,IQGAP3,TNFRSF11A,SPRY2,SYK,VEGFC,RAPGEF2,PRICKLE1,TLR6,GPLD1,GPR37,PTPRC,TRIB3,DOCK7,ACER2,MAP2K6,XBP1,LRRK1,BMP4,BTRC,ATP2B4,LARP1 |
| 1.584e-02 | -4.15 | GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 472 | 61 | 17377 | 1707 |
EPHA3,ID1,CELSR1,FGF13,RHOD,CKAP2,GPR65,EPS8,ARL2,NPM1,ADD2,NTRK3,SORBS3,GPSM2,PIBF1,PFN2,PPP1R9A,SPIRE1,FHOD3,SCIN,PPM1E,MAP1A,PRKCD,SGK1,CTTN,SLIT2,NEB,FES,PDGFRB,PAK1,PHLDB2,FER,SSH3,EVL,TMEM67,MYLK3,RHOQ,DSTN,ASAP3,PREX1,PRKCQ,WNT11,JAM3,EML1,BAIAP2,SNCA,SMAD3,GSN,PLEKHH2,MYADM,NCKAP1L,WIPF3,PLK2,MAP9,PAM,TMOD2,TMEFF2,TPM1,MID1,CHMP4C,MEF2C |
| 1.586e-02 | -4.14 | regulation of cell size | biological process | GO:0008361 | 166 | 25 | 17256 | 1658 |
PAK1,BDNF,VAV3,FN1,FGF13,BMPR2,DCC,DEPTOR,PLXNA2,NTRK3,SLC12A6,MAP1B,NKX6-1,RND2,SEMA4F,AKT3,PTPRS,SEMA3C,CTTN,SPART,NRP1,IQGAP3,SEMA3A,PRR16,SHTN1 |
| 1.589e-02 | -4.14 | PyrdxlP-dep_Trfase | interpro domains | IPR015424 | 41 | 9 | 18492 | 1811 |
GPT2,MOCOS,AADAT,GCAT,PHYKPL,ABAT,ETNPPL,CTH,GLDC |
| 1.589e-02 | -4.14 | PyrdxlP-dep_Trfase_major | interpro domains | IPR015421 | 41 | 9 | 18492 | 1811 |
GPT2,MOCOS,AADAT,GCAT,PHYKPL,ABAT,ETNPPL,CTH,GLDC |
| 1.590e-02 | -4.14 | GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS | MSigDB lists | GO_MONOCARBOXYLIC_ACID_METABOLIC_PROCESS | 481 | 62 | 17377 | 1707 |
UST,PLA2G4A,PRKAA2,UGT8,ACSL1,ELOVL4,EHHADH,ALOX5AP,ENO2,CYP2J2,ELOVL7,OLAH,CYP4V2,STAT5B,SCD,ABAT,SLC1A3,LPIN3,BCAN,PHGDH,CYP26A1,MSMO1,KMO,FAAH2,ALDOC,GHR,FABP6,ENO1,SYK,GLDC,CYP1B1,PFKFB4,FADS1,VNN2,SESN2,GAPDH,PFKFB2,SLC27A2,ELOVL3,FASN,OGDHL,PRKAR2B,AMDHD1,LRAT,SNCA,DAGLA,MAPKAPK2,ALDOA,XBP1,TNFRSF1A,PAM,HK2,BDH2,P4HA1,HPGD,DSEL,CYP2U1,HK1,PPARGC1A,PTGES,ACSM3,CRYL1 |
| 1.590e-02 | -4.14 | BROWNE_HCMV_INFECTION_48HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_48HR_DN | 481 | 62 | 17377 | 1707 |
MAN2B2,FN1,IGFBP6,FGF13,ZHX3,ARHGEF11,PTPRD,XYLT1,PTPN21,TJP1,PPP2R3A,EFEMP1,FKBP9,BCHE,CDC14B,SLC22A18,RAP2A,NAP1L3,SERPINH1,MOXD1,RRAS2,ETV1,ZFP36L2,IGFBP3,DUSP1,DLGAP1,FADS1,MICAL2,RHOQ,SH3BP2,COL6A2,RAB3B,TDRD3,MVD,CACNA1E,DUSP9,TTC30A,CBY1,SKAP1,ASPH,FGFR1,MAP1B,GJC1,HEG1,SLC7A1,MAGEA12,ENPP1,MSC,MAP2,PEMT,AKT3,MAP2K6,C1orf21,MATN2,LAMB1,PCGF2,RAI14,ATG5,MMP16,CSRP2,DDIT3,LPP |
| 1.593e-02 | -4.14 | negative regulation of cellular response to insulin stimulus | biological process | GO:1900077 | 35 | 8 | 17256 | 1658 |
ENPP1,MSTN,PRKCB,GRB14,PRKCD,PRKCQ,GRB10,PTPRE |
| 1.593e-02 | -4.14 | negative regulation of toll-like receptor signaling pathway | biological process | GO:0034122 | 35 | 8 | 17256 | 1658 |
PTPRS,TYRO3,DAB2IP,TLR3,LGR4,TLR4,TLR6,SMPDL3B |
| 1.594e-02 | -4.14 | GO_RIBONUCLEOTIDE_BINDING | MSigDB lists | GO_RIBONUCLEOTIDE_BINDING | 1768 | 200 | 17377 | 1707 |
NMNAT3,MVK,ACVR1,ACSL1,KIF5A,ATP8A1,ASS1,TUBE1,PRKCA,AARS,RAC3,STK24,TUBB4A,MOK,RND2,RPS6KA2,DNAH6,RAP2A,RAB26,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,ABCC2,PRKAR2B,ROR1,ACVR2B,SGK2,GNAI1,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,PIK3C2B,MAPK13,DIRAS1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,BVES,RHOBTB1,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,IGF1R,EEF2,ABCA5,ADCK1,PDE10A,HS3ST5,PRKG1,ADCY6,ALPK1,FIGN,MAST4,NOS3,FGFR4,PAK1,RHOQ,SLC27A2,MYO10,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,HK2,RAB31,SLFN5,PANK3,ACSM3,EPHA3,MTG1,NEK10,DNM3,RHOD,MYO1B,CHUK,MAPK4,NTRK3,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,MET,RAB27B,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,PDK1,TUBA1A,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,TPK1,WARS,ENTPD1,PRKCB,GBP1,PTK7,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,EPHB1,PKN1,EHD3,RASD2,PRKCD,SGK3,GTF2F2,PRKG2,SGK1,ACTA2,DYNC2H1,PCK2,MYO6,RRAS2,SEPT3,SYK,ATP2B1,FES,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUAK2,AK4,AGAP2,MARS,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,AKT3,GNAO1,NEK11,PIP5KL1,KIF21A,LRRK1,HK1,GEM,CMPK2,KIF1B,ATP2B4,ATP1A3,ABCG1 |
| 1.595e-02 | -4.14 | V$OCT1_03 | MSigDB lists | V$OCT1_03 | 212 | 31 | 17377 | 1707 |
BDNF,MEIS2,FGF13,CHCHD7,FOXN3,PLAG1,JPH1,PLXNA2,COL4A5,PRDM1,CREB5,NEO1,FOXP2,SLC7A11,BACH2,KLF12,PRKG1,MPPED2,BEND4,DLX2,BMP4,PPP2R2B,ERRFI1,NRP1,RNF148,SEMA3A,LIFR,MID1,RIMS2,CTNND2,MEF2C |
| 1.598e-02 | -4.14 | haematopoietic_and_lymphoid_tissue-breast-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-breast-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 48 | 10 | 17385 | 1698 |
PLOD2,L3MBTL4,MAP2,RAPGEF2,GRIP1,GTF2IRD1,FBXO36,DNAH5,RIMS2,PCSK5 |
| 1.603e-02 | -4.13 | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 598 | 75 | 17377 | 1707 |
PPP4R4,DUSP8,DNAJC3,NDRG2,NPM1,NTRK3,CEBPA,PIBF1,SKI,PPM1E,PPP1R26,ZFYVE28,DACT1,CNKSR3,DAB2IP,PDE4D,TLR4,SLIT2,IGFBP3,SPOCD1,PTPN6,LRRK2,DEPTOR,PRKAR2B,ATF3,SYNJ2BP,SNCA,SMAD3,CAMK2N1,ENPP1,PTPRJ,NCKAP1L,GBP1,WWTR1,DUSP19,INPP5F,HGF,SPRY4,ATG5,PPARGC1A,MYO1D,LATS2,FARP1,UBASH3B,PKN1,DDIT4,MECOM,FRY,IGF1R,FLRT3,MYC,C1QL4,PRKCD,RASD2,LRP6,ERRFI1,SMAD6,SPRY2,DUSP1,HMGCR,DUSP9,DKK1,PTPRC,TRIB3,MYADM,PMEPA1,ACER2,DLG2,LRRK1,BMP4,SMYD3,TESC,PKIA,ATP2B4,SFN |
| 1.605e-02 | -4.13 | Thyroid hormone synthesis | KEGG pathways | hsa04918 | 74 | 14 | 7161 | 730 |
CREB3L2,ATF4,PRKCB,ADCY1,ADCY6,ITPR2,ATP1B1,CREB5,PRKCA,CANX,PLCB1,TSHR,PRKACB,ATP1A3 |
| 1.605e-02 | -4.13 | Thyroid hormone synthesis | KEGG pathways | ko04918 | 74 | 14 | 7161 | 730 |
CREB3L2,ATF4,PRKCB,ADCY1,ADCY6,ITPR2,ATP1B1,CREB5,PRKCA,CANX,PLCB1,TSHR,PRKACB,ATP1A3 |
| 1.606e-02 | -4.13 | RhoGEF | smart domains | SM00325 | 68 | 14 | 9493 | 1056 |
ARHGEF10L,VAV3,ARHGEF28,FARP1,ARHGEF11,RASGRF2,MCF2L2,MCF2L,PREX1,SPATA13,PLEKHG1,OBSCN,TIAM2,ARHGEF26 |
| 1.606e-02 | -4.13 | negative regulation of protein metabolic process | biological process | GO:0051248 | 1130 | 130 | 17256 | 1658 |
PHACTR3,PPP4R4,DUSP8,RECK,DNAJC3,LDLR,LILRB1,NPM1,NDRG2,CEBPA,CHAC1,SKI,PPM1E,PPP1R26,ZFYVE28,ITGB3,TLR4,SLIT2,LAMP3,CD55,SESN2,ATF4,COL4A3,LRRK2,DEPTOR,AGO4,PRKAR2B,ENPP1,SH3RF1,NCKAP1L,NCOA7,C8orf88,SERPINI1,INPP5F,SPRY4,PPARGC1A,SPOCK3,PRKAA2,LATS2,UBASH3B,DHCR24,OPHN1,TNFRSF10C,SPINK5,GAS1,RPL13A,MECOM,DDIT4,FRY,IGF1R,PAIP2B,BACE2,MYC,FLRT3,C1QL4,LRP6,HMGCR,BOD1,DUSP9,HERPUD1,CPEB1,BEX4,PMEPA1,LAPTM4B,SMYD3,TESC,SFN,PRKN,PCSK1N,C4A,NTRK3,PIBF1,RIDA,CNKSR3,DACT1,MAGEA3,DAB2IP,PROS1,PDE4D,FHIT,SERPINH1,IGFBP3,GAPDH,CSN2,NOP53,PTPN6,PREX1,ATF3,SYNJ2BP,C4BPB,WARS,SNCA,SMAD3,CAMK2N1,PTPRJ,BEX3,EIF4EBP1,GBP1,WWTR1,DUSP19,HGF,ATG5,IPO5,APBB1,UBAC2,IGF2BP2,GAS6,PKN1,MAP1A,RASD2,PRKCD,ERRFI1,SMAD6,ZFP36L2,SPRY2,DUSP1,CRIM1,PHACTR2,AGAP2,RACK1,DKK1,PTPRC,TRIB3,MYADM,ACER2,LRRK1,BMP4,PKIA,LARP1,ATP2B4 |
| 1.608e-02 | -4.13 | GO_REGULATION_OF_COAGULATION | MSigDB lists | GO_REGULATION_OF_COAGULATION | 84 | 15 | 17377 | 1707 |
HPSE,UBASH3B,PRKCD,PRKG1,HS3ST5,PRKCQ,ABAT,PROS1,F12,PRKCA,TLR4,TC2N,SYK,NOS3,F3 |
| 1.609e-02 | -4.13 | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP | MSigDB lists | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP | 179 | 27 | 17377 | 1707 |
DMXL2,GNG12,SESN2,LANCL3,SCAMP1,CLYBL,JDP2,MSR1,UBAC2,FASN,IL13RA1,C1R,CHSY1,TMEM170B,DNER,AARS,DDIT4,PCDH7,TRPS1,CYP51A1,FGR,IDI1,MAP2,PRELID2,EMILIN2,SMAD6,PTGES |
| 1.609e-02 | -4.13 | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN | 179 | 27 | 17377 | 1707 |
TNIK,CARD6,ZHX3,RNF144A,FBXO4,STAT4,BACE1,CYTH3,SPATA13,ZDHHC15,NPM1,NDRG2,ADAMTS6,RABAC1,GPSM2,DOCK2,SLCO3A1,KCNMB4,RALGPS2,KIAA0355,OSBPL5,RGS10,KIAA1614,OXTR,ARL4D,KIF1B,SMPDL3A |
| 1.609e-02 | -4.13 | GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP | 179 | 27 | 17377 | 1707 |
THOC5,SESN2,SLITRK2,TBC1D1,LRMP,CREB5,FAM174B,PLCB1,KBTBD11,DOCK2,HERPUD1,GABARAPL1,SMAD3,IFT81,RSL24D1,RPL12,EEF2,ENPP6,ALDOC,INPP4B,P4HA1,SVIL,LIN7A,SMYD3,DOCK8,TPT1,GAB2 |
| 1.609e-02 | -4.13 | GSE13229_IMM_VS_INTMATURE_NKCELL_UP | MSigDB lists | GSE13229_IMM_VS_INTMATURE_NKCELL_UP | 179 | 27 | 17377 | 1707 |
DLGAP1,PDK1,SIDT1,RNF144A,MCOLN3,SHISA2,KCND3,PKN1,IKZF2,TLR6,RADIL,SLCO3A1,PPP2R3A,FGR,CA2,PKN3,TACC2,ABCA5,KAZN,MCF2L,STARD4,ITGB3,SERINC2,TMEM132E,CLVS2,KIAA1549,GPR161 |
| 1.613e-02 | -4.13 | GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | 349 | 47 | 17377 | 1707 |
STXBP6,EPS8,BIK,ARL2,ADD2,PFN2,SNX9,PPP1R9A,FHOD3,SPIRE1,SCIN,UNC13B,PMAIP1,DACT1,PRKCD,GTF2F2,SGK1,HRK,DAB2IP,CTTN,TLR4,STXBP1,SMAD6,SLIT2,FES,FER,EVL,PREX1,TLR6,BAIAP2,DKK1,SNCA,BCL11A,TRIM9,GSN,MYADM,INSIG1,MPP7,PMEPA1,NCKAP1L,WIPF3,EIF4EBP1,CDH17,BBC3,ERCC5,TMOD2,CHMP4C |
| 1.613e-02 | -4.13 | L-serine metabolic process | biological process | GO:0006563 | 11 | 4 | 17256 | 1658 |
CBS,SERINC5,PHGDH,PSPH |
| 1.613e-02 | -4.13 | amyloid-beta clearance | biological process | GO:0097242 | 11 | 4 | 17256 | 1658 |
IGF1R,LDLR,MME,MSR1 |
| 1.613e-02 | -4.13 | negative regulation of humoral immune response | biological process | GO:0002921 | 11 | 4 | 17256 | 1658 |
CD55,SPINK5,PTPN6,C4BPB |
| 1.613e-02 | -4.13 | AV node cell to bundle of His cell communication | biological process | GO:0086067 | 11 | 4 | 17256 | 1658 |
TRPM4,SCN5A,CACNB2,GJC1 |
| 1.613e-02 | -4.13 | cerebral cortex GABAergic interneuron differentiation | biological process | GO:0021892 | 11 | 4 | 17256 | 1658 |
DLX2,RAC3,LHX6,NKX2-1 |
| 1.613e-02 | -4.13 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | biological process | GO:1990440 | 11 | 4 | 17256 | 1658 |
CEBPB,ATF3,ATF4,DDIT3 |
| 1.613e-02 | -4.13 | negative regulation of platelet aggregation | biological process | GO:0090331 | 11 | 4 | 17256 | 1658 |
ABAT,UBASH3B,PRKCD,PRKG1 |
| 1.613e-02 | -4.13 | type 2 immune response | biological process | GO:0042092 | 11 | 4 | 17256 | 1658 |
GATA3,BCL6B,BATF,BCL6 |
| 1.613e-02 | -4.13 | keratinocyte development | biological process | GO:0003334 | 11 | 4 | 17256 | 1658 |
BCL11B,EXPH5,PALLD,SFN |
| 1.614e-02 | -4.13 | Circadian entrainment | KEGG pathways | ko04713 | 96 | 17 | 7161 | 730 |
GNG12,ADCY1,RYR2,RASD1,GUCY1A2,PRKCA,PLCB1,NOS1AP,GNAI1,PRKCB,GNAO1,GNB4,PRKG1,ADCY6,PRKG2,GRIN2D,PRKACB |
| 1.614e-02 | -4.13 | Circadian entrainment | KEGG pathways | hsa04713 | 96 | 17 | 7161 | 730 |
GNG12,ADCY1,RYR2,RASD1,GUCY1A2,PRKCA,PLCB1,NOS1AP,GNAI1,PRKCB,GNAO1,GNB4,PRKG1,ADCY6,PRKG2,GRIN2D,PRKACB |
| 1.618e-02 | -4.12 | TTTGTAG,MIR-520D | MSigDB lists | TTTGTAG,MIR-520D | 323 | 44 | 17377 | 1707 |
SCN5A,TCTN2,ENAH,SCD,SPATS2L,SLC1A3,PFN2,TRPS1,SLC35F1,PPM1E,PPP1R26,LRRN1,RAP2A,NBEA,TOX,PDE4D,FAM84B,NCAM1,VGLL4,SCN3A,ATP2B1,GPM6A,ATF4,SLITRK2,FOXN3,DNAJC6,EDEM3,PRDM1,SNAP25,TMEM47,RNF44,MBNL2,DHX32,HTR7,RANBP2,KLF12,GNAO1,RAI14,PPARGC1A,NEUROG2,CDH2,FNBP1L,LPP,MEF2C |
| 1.618e-02 | -4.12 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_LARGE_VS_TINY_UP | 41 | 9 | 17377 | 1707 |
FADS1,GNG12,TUBA1A,LRRN1,GCAT,GNB4,MSR1,TLR6,FKBP11 |
| 1.618e-02 | -4.12 | GO_PROTEIN_KINASE_A_BINDING | MSigDB lists | GO_PROTEIN_KINASE_A_BINDING | 41 | 9 | 17377 | 1707 |
C2orf88,AKAP7,AKAP5,DACT1,LRRK2,RYR2,PRKAR2B,MYRIP,PKIA |
| 1.619e-02 | -4.12 | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP | MSigDB lists | LABBE_TARGETS_OF_TGFB1_AND_WNT3A_UP | 107 | 18 | 17377 | 1707 |
PLA2G4A,FGFR4,DBN1,RUNX2,BACE1,EFNA3,ASS1,ADSSL1,AK1,GSN,AKAP7,MAP2,BMP1,SGK1,NRP1,CDH2,CPE,DUSP1 |
| 1.621e-02 | -4.12 | negative regulation of response to oxidative stress | biological process | GO:1902883 | 56 | 11 | 17256 | 1658 |
GPR37,PRKN,ATF4,LRRK2,NCOA7,PDE8A,HGF,RACK1,MET,PYCR1,FZD1 |
| 1.622e-02 | -4.12 | CR1 (complement C3b/C4b receptor 1 (Knops blood group)) | protein interactions | 1378 | 6 | 3 | 17029 | 1718 |
CR2,CD55,C4A |
| 1.622e-02 | -4.12 | PRDM16 (PR/SET domain 16) | protein interactions | 63976 | 6 | 3 | 17029 | 1718 |
SMAD3,PATJ,SKI |
| 1.622e-02 | -4.12 | INHBC (inhibin subunit beta C) | protein interactions | 3626 | 6 | 3 | 17029 | 1718 |
ACVR2A,ACVR2B,ACVR1 |
| 1.622e-02 | -4.12 | IL17RD (interleukin 17 receptor D) | protein interactions | 54756 | 6 | 3 | 17029 | 1718 |
PTPRD,FGFR1,BTRC |
| 1.622e-02 | -4.12 | ARMH4 (armadillo-like helical domain containing 4) | protein interactions | 145407 | 6 | 3 | 17029 | 1718 |
BMPR1A,BMPR2,FGFR1 |
| 1.622e-02 | -4.12 | NTN1 (netrin 1) | protein interactions | 9423 | 6 | 3 | 17029 | 1718 |
UNC5C,DCC,NEO1 |
| 1.622e-02 | -4.12 | GSTM2 (glutathione S-transferase mu 2) | protein interactions | 2946 | 6 | 3 | 17029 | 1718 |
GSTM3,GSTM2,GSTM4 |
| 1.622e-02 | -4.12 | KCNB2 (potassium voltage-gated channel subfamily B member 2) | protein interactions | 9312 | 6 | 3 | 17029 | 1718 |
KCNV1,KCNB2,KCNS3 |
| 1.622e-02 | -4.12 | SP140L (SP140 nuclear body protein like) | protein interactions | 93349 | 6 | 3 | 17029 | 1718 |
LDHD,RAPGEF2,NEDD4 |
| 1.622e-02 | -4.12 | ADM (adrenomedullin) | protein interactions | 133 | 6 | 3 | 17029 | 1718 |
CALCRL,CFH,MME |
| 1.622e-02 | -4.12 | MUC5AC (mucin 5AC, oligomeric mucus/gel-forming) | protein interactions | 4586 | 6 | 3 | 17029 | 1718 |
GALNT14,GALNT12,GAN |
| 1.622e-02 | -4.12 | SVEP1 (sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1) | protein interactions | 79987 | 6 | 3 | 17029 | 1718 |
SMAD3,SMAD9,ZFYVE9 |
| 1.623e-02 | -4.12 | GO_MEMBRANE_MICRODOMAIN | MSigDB lists | GO_MEMBRANE_MICRODOMAIN | 280 | 39 | 17377 | 1707 |
MYO1D,SCN5A,RGS16,SORBS1,BMPR2,LRP4,EPHB1,LCP2,MLC1,NEDD4,NOS1AP,EEF2,LRP6,GRIP1,ADCY6,SERPINH1,ATP2B1,NOS3,RHOQ,CD55,ANK2,LRRK2,ADCY1,PRKAR2B,ATP1B1,TLR6,GNAI1,PTPRC,MYADM,HPSE,GPRC5B,TNFRSF1A,HK1,BMPR1A,UNC5B,CDH2,ATP2B4,STOM,CNTN1 |
| 1.624e-02 | -4.12 | Sushi_SCR_CCP_dom | interpro domains | IPR000436 | 55 | 11 | 18492 | 1811 |
SUSD3,CD55,CFH,CFHR1,SELL,CR2,C1R,BCAN,SEZ6L2,SUSD4,C4BPB |
| 1.627e-02 | -4.12 | FERM_domain | interpro domains | IPR000299 | 48 | 10 | 18492 | 1811 |
FRMPD3,EPB41L5,EPB41L3,PLEKHH2,FARP1,MYO10,PTPN13,PTPN21,TLN2,FRMD5 |
| 1.627e-02 | -4.12 | GO_MUSCLE_ADAPTATION | MSigDB lists | GO_MUSCLE_ADAPTATION | 28 | 7 | 17377 | 1707 |
GSN,INPP5F,PPARGC1A,IL15,MSTN,NOS3,MEF2C |
| 1.627e-02 | -4.12 | TCGA_GLIOBLASTOMA_COPY_NUMBER_DN | MSigDB lists | TCGA_GLIOBLASTOMA_COPY_NUMBER_DN | 28 | 7 | 17377 | 1707 |
CAB39L,SETDB2,EBPL,FNDC3A,KPNA3,ENO1,RERE |
| 1.628e-02 | -4.12 | LEIN_NEURON_MARKERS | MSigDB lists | LEIN_NEURON_MARKERS | 62 | 12 | 17377 | 1707 |
CHN1,RTN1,SLC22A17,SH3GL2,RYR2,ADD2,SNAP25,PACSIN1,SYNGR3,DISP2,BEX2,GABARAPL1 |
| 1.628e-02 | -4.12 | chr13q12 | MSigDB lists | chr13q12 | 62 | 12 | 17377 | 1707 |
SLC7A1,WASF3,SUGT1,ALOX5AP,SMAD9,EBPL,RPL21,CCNA1,SPATA13,SHISA2,TNFRSF19,SLC46A3 |
| 1.629e-02 | -4.12 | JAEGER_METASTASIS_DN | MSigDB lists | JAEGER_METASTASIS_DN | 246 | 35 | 17377 | 1707 |
BCL11B,EXPH5,CFH,ST14,MCOLN3,GATA3,ASS1,SPINK5,TPD52L1,FHOD3,HOPX,CDS1,ABLIM1,CHN2,CA2,MAP7,EPHB6,MYO6,MAST4,PERP,SSH3,MID2,ALDH2,ARAP2,ARHGAP32,KCND3,DSP,BCL11A,HLF,MATN2,TUFT1,MAPK13,KLF5,COBL,SFN |
| 1.630e-02 | -4.12 | TNFR_c6 | pfam domains | PF00020 | 22 | 6 | 17054 | 1666 |
TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A |
| 1.631e-02 | -4.12 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_DN | 171 | 26 | 17377 | 1707 |
SEMA6B,ARAP2,DYRK3,IL15,HERC5,SLC25A28,GPR180,HERC6,TCERG1L,SEMA6A,PRRG4,COL27A1,WARS,GALNT3,OTUD1,PDZD7,PMAIP1,NCOA7,TNFSF15,SP140,CMPK2,SLFN5,CSRP2,SP140L,STOM,LAMP3 |
| 1.631e-02 | -4.12 | GO_PLASMA_MEMBRANE_RECEPTOR_COMPLEX | MSigDB lists | GO_PLASMA_MEMBRANE_RECEPTOR_COMPLEX | 171 | 26 | 17377 | 1707 |
ITGB7,ACVR1,SORBS1,CACNG3,ACVR1C,GRIK2,PTPN6,ITGA6,SHANK2,EPS8,CHRNA6,CHUK,IL13RA1,CD40,SKAP1,ABHD6,TLR6,NOS1AP,GRIK4,CHRNA5,ITGB3,ITGA2,GRIN2D,DLG2,BMPR1A,SYK |
| 1.631e-02 | -4.12 | GO_MUSCLE_TISSUE_DEVELOPMENT | MSigDB lists | GO_MUSCLE_TISSUE_DEVELOPMENT | 263 | 37 | 17377 | 1707 |
ACVR1,BVES,PKP2,DNER,FHOD3,SKI,FOXP2,TGFBR3,EOMES,EEF2,KCNAB1,DSG2,COL19A1,MYH15,MARCKS,PDGFRB,MYLK3,FHL2,RYR2,ATF3,CBY1,ZFPM2,DSP,GJC1,HEG1,MSC,HLF,PLAGL1,HEYL,SVIL,KLF5,SEMA3C,BMP4,ATG5,KLHL31,TPM1,MEF2C |
| 1.644e-02 | -4.11 | GO_EMBRYONIC_ORGAN_DEVELOPMENT | MSigDB lists | GO_EMBRYONIC_ORGAN_DEVELOPMENT | 402 | 53 | 17377 | 1707 |
THOC5,ACVR1,RUNX2,CELSR1,ST14,OTX1,GATA3,CEBPA,OVOL2,EFEMP1,SETDB2,EOMES,PDZD7,GATA2,DLX6,TFAP2A,SPRY2,GLI1,MICAL2,MSX1,NKX3-2,RYR2,MAFB,YAP1,WNT11,SATB2,PRDM1,ATOH1,RARRES2,ZFPM2,HOXA1,FGFR1,ZIC1,CEBPB,SMAD3,ID3,INSIG1,FBN1,PTK7,WDR19,PCGF2,DLX2,BMP4,BMPR1A,NRP1,SHOX2,MMP16,COBL,SIX2,DDIT3,MEF2C,PCSK5,HEY1 |
| 1.646e-02 | -4.11 | glycoprotein metabolic process | biological process | GO:0009100 | 375 | 49 | 17256 | 1658 |
CCDC126,UST,MAN2B2,GXYLT2,BMPR2,GALNT12,GALNT6,ST6GAL1,XYLT1,ALG1L,GALNT13,CHSY1,MGAT5B,BCAN,GBGT1,GALNT1,MGAT1,FUT9,HS3ST5,COG3,ST8SIA1,GALNT18,PCSK6,ALG10B,B4GALT6,CHSY3,B3GALT1,B3GLCT,GCNT2,MVD,MGAT4B,EDEM3,ST6GALNAC3,GALNT17,PXYLP1,GALNT14,GLCE,DPY19L2,GALNT3,HPSE,PLOD2,SRD5A3,B3GALT2,ALG11,DSEL,HS3ST3B1,SPOCK3,B4GALT7,HS6ST3 |
| 1.648e-02 | -4.11 | XU_GH1_EXOGENOUS_TARGETS_DN | MSigDB lists | XU_GH1_EXOGENOUS_TARGETS_DN | 115 | 19 | 17377 | 1707 |
PFKFB4,SYNPO2,USP2,RNF144A,ESRRG,GPR180,INTS6,GPLD1,HPSE,WFS1,RASGRF2,ITGB3,SGK1,SH3BGRL2,PURG,SPRY2,SNAI2,MED12L,CES3 |
| 1.648e-02 | -4.11 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_DN | 115 | 19 | 17377 | 1707 |
DMXL2,AMOTL1,LRP4,JPH1,BIK,HECW2,CADM2,GUCY1A2,RBM11,CENPV,TMEM74,BHLHA15,REEP1,ZIC5,TMEM143,SLC6A15,STXBP1,PDGFRB,HS6ST3 |
| 1.650e-02 | -4.10 | positive regulation of MAP kinase activity | biological process | GO:0043406 | 269 | 37 | 17256 | 1658 |
TENM1,TNIK,NEK10,AVPI1,FZD8,NTRK3,PKN1,TPD52L1,STK24,GHR,INAVA,DAB2IP,IQGAP3,TLR4,TNFRSF11A,SYK,RASGRP1,PDGFRB,PAK1,FZD4,TGFA,LRRK2,DUSP9,CD40,TLR6,FGFR1,DKK1,MAPKAPK2,MAP2K6,ERN1,MAP3K21,DUSP19,DIRAS1,HGF,BMP4,MAPK10,MAP3K20 |
| 1.652e-02 | -4.10 | muscle contraction | biological process | GO:0006936 | 243 | 34 | 17256 | 1658 |
SCN5A,SORBS1,ARHGEF11,PKP2,SORBS3,CHUK,EEF2,KCNN2,SCN1B,CACNB2,SMTN,ACTA2,PDE4D,NEB,CHRM3,PXN,ANK2,FGF12,RYR2,VIM,ATP1B1,KCND3,SNTB1,ASPH,GJC1,HTR7,MAP2K6,GNAO1,ALDOA,MYOM2,TMOD2,OXTR,TPM1,CACNA2D1 |
| 1.654e-02 | -4.10 | endochondral bone morphogenesis | biological process | GO:0060350 | 49 | 10 | 17256 | 1658 |
INPPL1,RUNX2,BMPR2,BMP4,SERPINH1,SHOX2,MMP16,BMP6,COL27A1,MEF2C |
| 1.654e-02 | -4.10 | replacement bone morphogenesis | biological process | GO:0061971 | 49 | 10 | 17256 | 1658 |
INPPL1,RUNX2,BMPR2,BMP4,SERPINH1,SHOX2,MMP16,BMP6,COL27A1,MEF2C |
| 1.658e-02 | -4.10 | GO_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | GO_SMAD_PROTEIN_SIGNAL_TRANSDUCTION | 55 | 11 | 17377 | 1707 |
SMAD3,INHBC,SMAD9,MSTN,INHBE,BMP1,VIM,BMP4,MAGI2,BMP6,SKI |
| 1.658e-02 | -4.10 | GO_NEURON_NEURON_SYNAPTIC_TRANSMISSION | MSigDB lists | GO_NEURON_NEURON_SYNAPTIC_TRANSMISSION | 55 | 11 | 17377 | 1707 |
SLC6A9,UNC13B,GRIK2,GABRB2,RASD2,GABRG2,TMOD2,CACNB4,KIF1B,RAC3,SNCA |
| 1.659e-02 | -4.10 | GO_GLOMERULUS_DEVELOPMENT | MSigDB lists | GO_GLOMERULUS_DEVELOPMENT | 48 | 10 | 17377 | 1707 |
COL4A3,LGR4,COL4A4,HEYL,WWTR1,ACTA2,BMP4,MAGI2,PDGFRB,MEF2C |
| 1.659e-02 | -4.10 | GO_POSITIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION | 48 | 10 | 17377 | 1707 |
ACVR2A,INHBC,BMPR1A,ACVR1,BMP4,BMPR2,MSTN,BMP6,INHBE,BMP1 |
| 1.659e-02 | -4.10 | MARCHINI_TRABECTEDIN_RESISTANCE_DN | MSigDB lists | MARCHINI_TRABECTEDIN_RESISTANCE_DN | 48 | 10 | 17377 | 1707 |
SLC3A2,RND3,RUSC2,SLC7A5,ACTA2,MARS,SLC1A5,TPM1,PKN1,PYCR1 |
| 1.660e-02 | -4.10 | GO_VESICLE_MEMBRANE | MSigDB lists | GO_VESICLE_MEMBRANE | 491 | 63 | 17377 | 1707 |
DOC2A,DMXL2,SV2B,CACNG3,SCAMP1,SEC24D,RNF144A,ATP8A1,SYT12,BACE1,VAMP8,LDLR,MSR1,SNX9,SPIRE1,PCDH7,RAB11FIP5,RND2,KCNJ4,ITGB3,RAB26,SREBF1,MARCH3,CADPS2,PACSIN1,CLVS2,MYO6,RAB27B,SYNGR3,MYRIP,CPE,GPR161,NOS3,SNX7,LAMP3,TNK2,TMEM67,RHOQ,ABCC4,FZD4,TGFA,WLS,LRRK2,HIP1,PHACTR2,RAB38,FNDC3A,TLR6,GABARAPL1,SNCA,ARHGAP21,ICA1,SH3GL2,GPRC5B,ENTPD7,PAM,AHNAK2,RAB31,PTPRN2,ATG5,TBC1D4,KIF1B,SFN |
| 1.663e-02 | -4.10 | cellular response to peptide | biological process | GO:1901653 | 313 | 42 | 17256 | 1658 |
GNG12,SORBS1,ID1,ATP6V1E2,ASS1,STAT5B,NKX6-1,CA2,IGF1R,PRKCD,GHR,SREBF1,ADCY6,ERRFI1,PCK2,TLR4,TSHR,PRKACB,PAK1,FER,RHOQ,PXN,NR4A1,ADCY1,MARS,PRKAR2B,TLR6,BAIAP2,CPEB1,GPLD1,IRS2,TRIB3,ENPP1,FBN1,EIF4EBP1,GNB4,XBP1,RAB31,KLF5,TBC1D4,CACNA2D1,ATP1A3 |
| 1.671e-02 | -4.09 | MODULE_45 | MSigDB lists | MODULE_45 | 563 | 71 | 17377 | 1707 |
ACSL1,IL13RA1,KIF21B,LCP2,DENND3,DOCK2,RAC3,CYP26A1,CD53,TYMP,KCNAB1,CPVL,HPS1,TACC2,BCL6,FHIT,PTPRE,IL1RAP,RASGRP1,SEMA6C,PRKACB,CYP1B1,ITGB7,CD55,SKAP2,PNRC1,PFKFB2,PTPN6,LRMP,KCND3,ISG20,HTR7,INHBC,PRKCB,GBP1,RGS10,BMP1,LPAR2,IL32,ALOX5AP,REL,ITGA6,ST6GAL1,SELL,ZIC2,TNFRSF10C,PKN1,SATB1,KCNJ4,SLC7A11,PRKCD,CADPS2,PTPRCAP,TBC1D9,SYK,PFKFB4,FADS1,KCNQ3,MPP1,STAT4,ATP11A,SKAP1,HEG1,PTPRC,CD37,FGR,RAB31,KIAA0513,PAX9,MME,SLC43A1 |
| 1.673e-02 | -4.09 | GO_STRIATED_MUSCLE_ADAPTATION | MSigDB lists | GO_STRIATED_MUSCLE_ADAPTATION | 22 | 6 | 17377 | 1707 |
GSN,INPP5F,PPARGC1A,IL15,MSTN,MEF2C |
| 1.673e-02 | -4.09 | GO_SEMAPHORIN_RECEPTOR_BINDING | MSigDB lists | GO_SEMAPHORIN_RECEPTOR_BINDING | 22 | 6 | 17377 | 1707 |
SEMA3C,SEMA6B,SEMA4F,SEMA3A,SEMA6A,SEMA6C |
| 1.673e-02 | -4.09 | GO_ACTIN_FILAMENT_POLYMERIZATION | MSigDB lists | GO_ACTIN_FILAMENT_POLYMERIZATION | 22 | 6 | 17377 | 1707 |
COBLL1,WASF3,GSN,CTTN,COBL,PREX1 |
| 1.673e-02 | -4.09 | BIOCARTA_SPPA_PATHWAY | MSigDB lists | BIOCARTA_SPPA_PATHWAY | 22 | 6 | 17377 | 1707 |
PLA2G4A,PRKCA,PRKCB,PLCB1,SYK,GNAI1 |
| 1.673e-02 | -4.09 | GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS | 22 | 6 | 17377 | 1707 |
COL18A1,GSN,BMP4,CD40,PPARGC1A,XBP1 |
| 1.673e-02 | -4.09 | GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | 22 | 6 | 17377 | 1707 |
SMAD3,ACVR2A,ACVR2B,ACVR1,BMPR2,ACVR1C |
| 1.673e-02 | -4.09 | GO_CAMP_BINDING | MSigDB lists | GO_CAMP_BINDING | 22 | 6 | 17377 | 1707 |
PRKAR2B,PDE4D,BVES,PDE10A,RAPGEF2,RAPGEF4 |
| 1.673e-02 | -4.09 | NIKOLSKY_OVERCONNECTED_IN_BREAST_CANCER | MSigDB lists | NIKOLSKY_OVERCONNECTED_IN_BREAST_CANCER | 22 | 6 | 17377 | 1707 |
FOXP2,TCF7L1,KDM5B,STAT4,XBP1,MEF2C |
| 1.673e-02 | -4.09 | GO_BENZENE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_BENZENE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 22 | 6 | 17377 | 1707 |
GSTM3,GSTM2,AADAT,KMO,TDO2,GSTM4 |
| 1.673e-02 | -4.09 | GO_ENDOCARDIAL_CUSHION_MORPHOGENESIS | MSigDB lists | GO_ENDOCARDIAL_CUSHION_MORPHOGENESIS | 22 | 6 | 17377 | 1707 |
MSX1,BMPR1A,HEYL,DCHS1,SNAI2,HEY1 |
| 1.674e-02 | -4.09 | regulation of microtubule polymerization or depolymerization | biological process | GO:0031110 | 71 | 13 | 17256 | 1658 |
PAK1,TUBB4A,FGF13,MAP1A,MAP2,CKAP2,ARL2,HDGFL3,MET,MID1,FES,SNCA,MAP1B |
| 1.674e-02 | -4.09 | outflow tract morphogenesis | biological process | GO:0003151 | 71 | 13 | 17256 | 1658 |
ACVR1,TGFBR3,BMPR2,HEYL,SEMA3C,WNT11,BMPR1A,BMP4,ZFPM2,NRP1,SMAD6,FZD1,MEF2C |
| 1.674e-02 | -4.09 | GSE3920_UNTREATED_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_UNTREATED_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | 147 | 23 | 17377 | 1707 |
CARS,RGS16,HBG2,SLC3A2,GARS,GRIK2,SH2D2A,MYO10,REL,LITAF,CHAC1,SEMA6A,PRRG4,FGFR1,BAIAP2,SLC7A1,TRIB3,CXCL10,PMEPA1,RND3,MFSD2A,FLRT3,FAM84B |
| 1.675e-02 | -4.09 | response to glucose | biological process | GO:0009749 | 142 | 22 | 17256 | 1658 |
PRKAA2,SESN2,COL6A2,ACVR1C,PFKFB2,GAS6,ACVR2B,RACK1,ILDR2,GPLD1,NKX6-1,RAB11FIP5,IRS2,UNC13B,IGF1R,CTSV,ERN1,XBP1,SREBF1,PTPRN2,PPARGC1A,PCK2 |
| 1.676e-02 | -4.09 | MYO19 (myosin XIX) | protein interactions | 80179 | 175 | 27 | 17029 | 1718 |
DBN1,PHLDB2,MYO10,MYO1B,TJP1,PALLD,PPP1R9A,GNAI1,GSN,ABLIM1,ARHGAP21,DOCK7,MYADM,FCHO2,DSG2,GAS2L3,RAI14,SVIL,ZBTB20,LIMCH1,CTTN,MYO6,TPM1,STON2,COBL,KIAA1211,STOM |
| 1.679e-02 | -4.09 | GO_INNER_EAR_MORPHOGENESIS | MSigDB lists | GO_INNER_EAR_MORPHOGENESIS | 92 | 16 | 17377 | 1707 |
CELSR1,OTX1,GATA3,MAFB,ATOH1,HOXA1,FGFR1,ZIC1,INSIG1,GATA2,PDZD7,PTK7,DLX6,TFAP2A,NRP1,SPRY2 |
| 1.679e-02 | -4.09 | V$STAT3_02 | MSigDB lists | V$STAT3_02 | 139 | 22 | 17377 | 1707 |
BCL7A,SV2B,ARAP2,MEIS2,ADM2,NR4A1,ZFYVE9,NELL2,KCNN2,PCBP4,HEYL,PPFIA2,SLCO5A1,GRIN2D,BMP4,TMEM37,NCAM1,SHOX2,MYT1,HOXB9,DDIT3,HS6ST3 |
| 1.686e-02 | -4.08 | GO_TRANSPORTER_ACTIVITY | MSigDB lists | GO_TRANSPORTER_ACTIVITY | 1201 | 140 | 17377 | 1707 |
CACNG3,SIDT1,FLVCR2,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,CACNB4,NUP62CL,SLCO3A1,NCS1,SLC9A7,KCNN2,KCNAB1,SLC16A2,SLC22A18,SLC10A7,SERINC2,KCNS3,TRPC1,SLC2A12,TMEM37,COG3,GPM6A,SLC3A2,KCNIP3,ABCC4,GJB2,ATOX1,ABCC2,KCND3,SPNS1,SFXN1,SLC7A1,KCNMB4,ATP7B,SLC9B1,KCNV1,TMEM63C,SCN5A,SV2B,GABRB2,SCN8A,ATP6V1E2,SLC36A4,SLC1A3,MLC1,MCOLN2,SLC7A11,SLC30A4,ABCA5,CACNB2,PRELID2,PRELID1,LRP6,SLC16A9,NIPAL2,SLCO4C1,HBG2,SLC37A1,KCNQ3,SLC36A1,SLC27A2,PLEKHA8,VLDLR,TTYH2,CALCRL,RYR2,STEAP1,TMCO3,GRIK4,KCNK15,MFSD2A,SLC2A6,CDH17,TRPC3,SLC7A2,SLC19A2,CHRNA5,SLC22A17,FABP6,CLVS2,SCN2A,ATP6AP1L,KCNB2,SCN3A,CSN2,SLC39A8,KCNH5,SFXN4,CHRNA6,ATP1B1,ATP10D,GJC1,SLC39A14,KPNA3,KCNG1,DISP1,DENND5B,ANO10,SERINC5,SLC6A9,PLSCR4,ATP9A,IPO5,GABRG2,HBE1,GABRR2,SLC12A6,GAS6,SFXN3,KCNC4,MCU,KCNJ4,SCN1B,KCNMB3,SLC6A15,IPCEF1,SLC45A3,ATP2B1,TRPM4,SLC40A1,CACNA1E,GRID1,RASA3,ATP11A,MFSD9,OSBPL5,SLC7A5,SLCO5A1,GRIN2D,SLC22A15,SLC1A5,CACNA2D1,SLC16A10,ATP2B4,ATP1A3,SLC43A1,ABCG1 |
| 1.687e-02 | -4.08 | SH3 domain binding | molecular function | GO:0017124 | 124 | 20 | 17224 | 1680 |
PRKN,INPPL1,SH3BP2,PLSCR4,EVL,DOCK1,SH2D2A,AKAP5,PTPN6,SHANK2,DNAJC6,ENAH,DOCK3,SKAP1,KHDRBS2,WIPF3,AFAP1L2,DAB2IP,SH3BGRL2,ERRFI1 |
| 1.692e-02 | -4.08 | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | 188 | 28 | 17377 | 1707 |
SEMA6B,GNG12,GARS,SH3BP2,DYRK3,GAPDH,CELSR1,SLC27A2,TGFA,MLF1,FERMT2,RNF24,SCD,SNCA,HEG1,GPR37,UNC13B,AKT3,ITGB3,EIF1,OPN3,GSTM3,BBC3,MPDZ,HK1,ESD,GPR161,CYP1B1 |
| 1.692e-02 | -4.08 | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_DN | 188 | 28 | 17377 | 1707 |
WASF3,ESRRG,RUSC2,CBS,ATF3,SATB2,SHISA2,ZFPM2,CD40,FOXG1,WARS,QPRT,PLS3,MAPKAPK2,IRS2,ATXN7L1,CXCL10,IFT81,TMCO3,PTPRJ,LAMB1,HPGD,CTTN,PTPRE,BARX1,CSRP2,RAB30,CEBPD |
| 1.692e-02 | -4.08 | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN | 188 | 28 | 17377 | 1707 |
TRPM4,RHOQ,TUBA1A,EBPL,GCAT,TES,SPATA6,IGF2BP2,C3orf70,PHGDH,SMPDL3B,RTN1,HTR7,RNF180,GNB4,PCBP4,EMILIN2,XBP1,OPN3,DUSP19,TUFT1,PTPRS,SQLE,TANC2,SLC1A5,TMEM120B,LRP12,NUDT17 |
| 1.692e-02 | -4.08 | GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_UP | MSigDB lists | GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_UP | 188 | 28 | 17377 | 1707 |
KCNV1,TRIM2,FZD4,SYT12,CAP2,SYBU,FEZ1,PEX5L,KIF21B,ZDHHC14,PCDH7,GJC1,GPR37,ATXN7L1,PCBP4,LHX6,QPCTL,ALDH1L1,MPP2,ATRNL1,NEK11,BBC3,PPP2R2B,SCN2A,MYO6,NEUROG2,COBL,CNTN1 |
| 1.692e-02 | -4.08 | GSE3982_CTRL_VS_LPS_48H_DC_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_48H_DC_DN | 188 | 28 | 17377 | 1707 |
LPAR2,PODXL2,ALDH2,REL,TGFA,ARHGAP22,BEGAIN,HERC5,STAT5B,PRKAR2B,ATF3,ATP11A,SLCO3A1,TSKU,HEG1,ISG20,CHN1,CXCL10,ABCA5,RND3,CSF1,BDH2,SP140,CTTN,STOM,DUSP1,IGFBP3,LAMP3 |
| 1.692e-02 | -4.08 | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN | MSigDB lists | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN | 188 | 28 | 17377 | 1707 |
DLGAP1,GPR63,PTCH2,FARP1,USP2,IL15,ITPRIP,BTNL9,LSM11,NDRG2,TNKS1BP1,ARHGEF26,NOS1AP,SMAD3,ATXN7L1,LRRC6,SEMA4F,PLAGL1,HPS1,ABI3BP,AFF2,FAT1,IQGAP3,PTPRCAP,FES,DDIT3,CSRP2,MEF2C |
| 1.692e-02 | -4.08 | GSE29949_MICROGLIA_BRAIN_VS_CD8_NEG_DC_SPLEEN_UP | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_CD8_NEG_DC_SPLEEN_UP | 188 | 28 | 17377 | 1707 |
RWDD2A,GPR176,RGS16,SMAD9,LGALS3,NR4A1,MGST3,NDRG2,CHUK,HBE1,F12,CHN1,SLC39A14,EPB41L3,UNC13B,FRY,GPRC5B,HPS1,CNNM2,LAPTM4B,BMPR1A,MET,LIFR,HSPA2,ZFP36L2,NEB,ATP2B1,ZNF629 |
| 1.692e-02 | -4.08 | GSE7852_LN_VS_THYMUS_TCONV_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_UP | 188 | 28 | 17377 | 1707 |
CREB3L2,LATS2,ANTXR2,AVPI1,TRIM2,PDK1,LANCL3,TTC39B,LGR4,RNF144A,PRSS12,RAB6B,ITGA6,LDLR,CYP4V2,NUAK2,SCD,IL18R1,QPRT,CEBPB,SLC7A1,ENPP1,SIPA1L2,INSIG1,ALDOA,RUNDC3B,MAP7,SLC1A5 |
| 1.697e-02 | -4.08 | PLC-gamma1 signalling | REACTOME pathways | R-HSA-167021 | 36 | 8 | 10287 | 971 |
PDE1B,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PRKCA,PRKACB |
| 1.697e-02 | -4.08 | EGFR interacts with phospholipase C-gamma | REACTOME pathways | R-HSA-212718 | 36 | 8 | 10287 | 971 |
PDE1B,PRKCD,ADCY1,ADCY6,PRKAR2B,ITPR2,PRKCA,PRKACB |
| 1.699e-02 | -4.08 | glucocorticoid receptor binding | molecular function | GO:0035259 | 11 | 4 | 17224 | 1680 |
SMAD3,GRIP1,STAT5B,NR4A1 |
| 1.699e-02 | -4.08 | glutathione binding | molecular function | GO:0043295 | 11 | 4 | 17224 | 1680 |
GSTM3,GSTM2,PTGES,GSTM4 |
| 1.699e-02 | -4.08 | positive regulation of cellular biosynthetic process | biological process | GO:0031328 | 1801 | 199 | 17256 | 1658 |
THOC5,ACVR1,LGR4,TRIM16,DNAJC3,LDLR,LILRB1,ASS1,GATA3,NPM1,CTBP2,STAT5B,CEBPA,IKZF2,NOS1AP,TRPS1,SKI,EPCAM,ARHGEF10L,EOMES,GRHL1,ETV1,TLR4,TSHR,FANK1,ENO1,POU3F3,PDGFRB,NKX2-1,SESN2,MEIS2,ATF4,SMAD9,NR6A1,NFIA,NFE2L1,YAP1,MEF2B,BATF,AHRR,DYRK1B,HLF,INSIG1,ADRB1,NCOA7,TNFRSF1A,DLX2,PPARGC1A,MLLT3,MEF2C,BCL11B,PRKAA2,RUNX2,ITGA6,FBXO4,ZIC2,MECOM,ZBTB38,EEF2,GATA2,MYC,SREBF1,EBF4,LRP6,GRIP1,GLIS1,PRR16,BARX1,CAND2,GPR161,CEBPD,NOS3,FGFR4,RPL26,RAX,RHOQ,MSTN,STAT4,FHL2,WWC1,MAFB,SMARCD3,TAF4B,PLCB1,MAPKAPK2,PLAGL1,HEYL,HOXD13,NKX2-8,SMYD3,TESC,SIX2,CREB3L2,PRKN,SORBS1,ZNF516,IL15,OTX1,CHUK,LPIN3,TLR3,STARD4,ACVR2A,DAB2IP,POU2F2,MET,GLI1,ALG10B,FZD1,PFKFB2,FZD4,SOX21,VIM,PRKCQ,WNT11,SATB2,ATF3,PXYLP1,ATOH1,PYGO1,CD40,FGFR1,SNCA,IRS2,ZNF711,SMAD3,CXCL10,IKZF3,PEMT,WWTR1,ITGA2,SOHLH2,HGF,KLF5,BMPR1A,DBP,HOXB9,HEY1,BMPR2,CKAP2,ARHGEF11,FZD8,REL,CD276,PLAG1,APBB1,P2RY1,CREB5,OVOL2,ZNF219,BMP6,NKX6-1,KDM7A,BHLHA15,PRKCD,GTF2F2,TFAP2A,AFAP1L2,YBX3,MYO6,SMAD6,SYK,SLC45A3,MED12L,PARP9,PFKFB4,MICAL2,SLC40A1,MSX1,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,MARS,AGAP2,RACK1,ZFPM2,GUCY1A2,SKAP1,TLR6,HOXA1,ZIC1,GPLD1,RERE,EBF1,CEBPB,NSD1,DDAH1,TERT,XBP1,MYRF,PAX9,BMP4,SHOX2,DDIT3,LARP1,BTRC,FOXA1 |
| 1.701e-02 | -4.07 | peptide secretion | biological process | GO:0002790 | 167 | 25 | 17256 | 1658 |
RAB3B,PNP,WLS,RAPGEF4,TNFSF13B,LILRB1,GATA3,ACVR2B,CANX,LCP2,TLR6,PCLO,ILDR2,CBLN1,RAB11FIP5,MCOLN2,RAB26,PTPRN2,STEAP3,POU2F2,ARL4D,TLR4,IL1RAP,RIMS2,PCSK5 |
| 1.707e-02 | -4.07 | chiasm | COSMIC cancer mutations | chiasm | 11 | 4 | 17385 | 1698 |
RNF130,NACC2,KIAA1549,GNAI1 |
| 1.707e-02 | -4.07 | ALMS1 (ALMS1, centrosome and basal body associated protein) | protein interactions | 7840 | 47 | 10 | 17029 | 1718 |
GTF2IRD1,LATS2,DNM3,LACC1,SKAP1,THSD4,MLF1,BTRC,CRYL1,GAN |
| 1.707e-02 | -4.07 | skin-lower_leg-malignant_melanoma | COSMIC cancer mutations | skin-lower_leg-malignant_melanoma | 140 | 22 | 17385 | 1698 |
FER,EML5,CACNG3,PTPRD,DCC,PTPN13,PTPN21,TNS1,EPHB1,KHDRBS2,PTPRC,TMEM132B,IKZF3,PTPRJ,ADAMTS3,PTK7,PTPRS,PTPRN2,KIF21A,MET,PTPRE,CHRM3 |
| 1.708e-02 | -4.07 | Laminin_G_1 | pfam domains | PF00054 | 11 | 4 | 17054 | 1666 |
PROS1,GAS6,FAT4,SLIT2 |
| 1.712e-02 | -4.07 | oxidoreduction coenzyme metabolic process | biological process | GO:0006733 | 126 | 20 | 17256 | 1658 |
NMNAT3,GAPDH,PNP,ENO2,PFKFB2,OGDHL,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,PGM2L1,HK1,MDH1B,PCK2,ENO1,PARP9,HMGCR,NUDT17 |
| 1.713e-02 | -4.07 | sulfur compound metabolic process | biological process | GO:0006790 | 358 | 47 | 17256 | 1658 |
UST,MVK,ACSL1,AASS,XYLT1,ELOVL7,CBS,STAT5B,SCD,CHSY1,CHAC1,BCAN,PHGDH,SLC19A2,HMGCS1,AADAT,GHR,HS3ST5,GSTM3,FAR2,ESD,B4GALT6,CTH,CHSY3,MICAL2,OPLAH,GDAP1,PODXL2,GSTM2,GSTM4,MVD,MGST3,ELOVL3,HACD1,FASN,ABCC2,GSTO1,GLCE,TPK1,ENPP1,GSTO2,TDO2,PEMT,DSEL,PTGES,SPOCK3,ACSM3 |
| 1.716e-02 | -4.06 | cell surface | cellular component | GO:0009986 | 755 | 89 | 18223 | 1724 |
CXCR5,IL15,LDLR,LILRB1,NRXN1,F3,CD53,EPCAM,TLR3,TGFBR3,KCNN2,PPFIA2,ITGB3,ACVR2A,MET,TLR4,TSHR,ENO1,HSPA2,PDGFRB,FZD1,INTU,ITGB7,ANTXR2,CD55,SLC3A2,FZD4,TGFA,KCNH5,CAPN5,NLGN4X,ABCC2,TNS1,ROR1,CD40,DCBLD2,ENPP1,CXCL10,PTPRJ,GPRC5B,ITGA2,ASIC1,TNFRSF1A,PAM,BMPR1A,ADGRA3,NRP1,TNFSF4,SCN5A,LRFN5,LPAR2,ROBO2,BMPR2,SCART1,TSPAN15,BACE1,ITGA6,CD276,LRP4,CLSTN2,SELL,P2RY1,SLC1A3,SLC7A11,BACE2,DSG2,GHR,LRP6,LMAN2,NCAM1,TNFRSF11A,GFRA1,IGSF3,PCSK6,CDH26,ATP5IF1,KCNQ3,BTNL9,FERMT2,PPFIA4,SDC3,HEG1,PTPRC,CTSV,CDH17,EGFL7,CDH2,MMP16,ABCG1 |
| 1.717e-02 | -4.06 | V$LFA1_Q6 | MSigDB lists | V$LFA1_Q6 | 230 | 33 | 17377 | 1707 |
CREB3L2,BCL11B,CCDC148,HEBP1,BACE1,XYLT1,GABRG2,SEMA6A,SPEG,KCNAB1,BCL6,NPTXR,ARL4D,JAKMIP3,TMEM132E,ETV1,FES,ZNF385A,NKX2-1,PDLIM7,NDUFA4L2,MSX1,TUBA1A,ACVR1C,NR4A1,EFNA3,OBSCN,NPC2,SMAD3,CEBPB,AKT3,GNAO1,RAB31 |
| 1.721e-02 | -4.06 | GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_DN | MSigDB lists | GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_DN | 180 | 27 | 17377 | 1707 |
CHSY3,RWDD2A,MICAL2,RIN2,MRC2,MARK1,GLIPR1L1,RBFOX2,APBB1,FHL2,ARL2,CREB5,OVOL2,SEL1L3,ZNF558,NELL2,IQCH,SEMA4F,SH3RF1,PTK7,THSD7B,SCARF2,BCL6,BMP1,TSPAN9,CYP1B1,CES3 |
| 1.721e-02 | -4.06 | GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_UP | 180 | 27 | 17377 | 1707 |
CGN,BDNF,LANCL3,STXBP6,RUSC2,CMTM8,GABRG2,NOTUM,CCDC85A,CREB5,C4BPB,SPATA7,ARHGEF26,LGI2,NELL2,CNTN4,GPRIN1,TDO2,KAZN,RAB31,RAI14,UACA,AFAP1L2,FAM149A,MARCKS,SHOX2,SEMA3A |
| 1.721e-02 | -4.06 | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN | 180 | 27 | 17377 | 1707 |
PAK1,TNK2,CARD6,GARS,EVL,SCAMP1,TES,LITAF,SPATA13,PHACTR2,AIG1,SLC46A3,SMAD3,ZNF827,PMEPA1,PLOD2,MAP2K6,CECR2,EHD3,C1orf21,NCOA7,ST8SIA1,NRP1,ZNF518B,MID1,ZFP36L2,AMPD1 |
| 1.721e-02 | -4.06 | GSE7852_TREG_VS_TCONV_THYMUS_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_THYMUS_DN | 180 | 27 | 17377 | 1707 |
EXPH5,ANKRD13D,PFKFB2,CAP2,ATP8A1,PTPN6,ELOVL7,RAPGEF4,TMEM170B,NPC2,GRK6,F12,SATB1,SLCO3A1,KREMEN1,SLC39A14,OTUD1,KCNMB4,GPRC5B,ZFYVE28,GTSF1,C1orf21,TMEM86A,ITGB3,TNFRSF1A,SGK1,SCN3A |
| 1.722e-02 | -4.06 | DENND4C (DENN domain containing 4C) | protein interactions | 55667 | 68 | 13 | 17029 | 1718 |
CGN,PHLDB2,NAV1,RALGPS2,RASAL2,PTPN13,MAP3K21,CBY1,LPIN3,TANC2,FAM110B,OSBPL6,GAB2 |
| 1.723e-02 | -4.06 | Coagulation_fac-like_Gla_dom | interpro domains | IPR017857 | 11 | 4 | 18492 | 1811 |
PRRG1,PROS1,GAS6,PRRG4 |
| 1.726e-02 | -4.06 | human chr14q31.3 | chromosome location | human chr14q31.3 | 14 | 4 | 26185 | 1967 |
EML5,GPR65,PTPN21,SPATA7 |
| 1.726e-02 | -4.06 | presynaptic active zone | cellular component | GO:0048786 | 36 | 8 | 18223 | 1724 |
UNC13B,PPFIA2,PPFIA4,CDH2,STXBP1,PCLO,RIMS2,ARHGAP44 |
| 1.727e-02 | -4.06 | GO_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 492 | 63 | 17377 | 1707 |
KCNV1,SCN5A,SLC6A9,CACNG3,SCN8A,MCOLN3,ATP6V1E2,ITPR2,GAS6,SLC1A3,SLC12A6,KCNC4,CACNB4,NCS1,SLC9A7,MCU,MCOLN2,KCNJ4,KCNN2,KCNAB1,SLC30A4,SCN1B,SLC22A18,CACNB2,KCNMB3,KCNS3,TRPC1,SLC6A15,TMEM37,SCN2A,NIPAL2,ATP6AP1L,SCN3A,KCNB2,ATP2B1,TRPM4,SLC40A1,GPM6A,SLC3A2,KCNIP3,KCNQ3,SLC36A1,KCNH5,CACNA1E,SLC39A8,ATOX1,RYR2,RASA3,KCND3,ATP1B1,SLC39A14,TMCO3,KCNK15,KCNMB4,ATP7B,KCNG1,SLC1A5,TRPC3,SLC9B1,ATP2B4,CACNA2D1,ATP1A3,DENND5B |
| 1.728e-02 | -4.06 | regulation of plasma membrane bounded cell projection assembly | biological process | GO:0120032 | 184 | 27 | 17256 | 1658 |
TENM1,FER,SSH3,GPM6A,DNM3,EVL,RHOQ,MYO10,TBC1D1,EPS8,PFN2,TBC1D16,TBC1D30,PPP1R9A,TBC1D2,TBC1D19,RIPOR2,PRKCD,DYNC2LI1,KLF5,PLD1,ATG5,NRP1,FNBP1L,COBL,SLIT2,TBC1D8 |
| 1.735e-02 | -4.05 | CHICAS_RB1_TARGETS_SENESCENT | MSigDB lists | CHICAS_RB1_TARGETS_SENESCENT | 528 | 67 | 17377 | 1707 |
GALNT6,KCTD12,SLC7A2,FKBP11,CPNE2,ZDHHC6,TRPC1,MARCKS,POU2F2,VWA5A,RAB27B,PLTP,CTH,IGFBP3,FZD1,COL6A2,ERGIC1,SLC39A8,CYB5R2,GJB2,PREX1,FEZ1,TCEAL3,ATP1B1,RAB38,CENPV,GJC1,ISG20,DCBLD2,SLC7A1,CXCL10,PDLIM3,HPSE,ITGBL1,EIF4EBP1,WWTR1,KCNG1,TNFSF15,HEY1,LPP,LRFN5,ENO2,CLGN,JDP2,RASD1,SEL1L3,PHGDH,DDIT4,RGS17,ZBTB38,NAV1,PRTFDC1,TSC22D1,JAM2,SNX7,FADS1,HIP1,SDC3,CDC42BPA,STEAP1,TRIB3,TIFA,PLAGL1,SRD5A3,RAB31,GEM,DCBLD1 |
| 1.741e-02 | -4.05 | GO_BUNDLE_OF_HIS_CELL_TO_PURKINJE_MYOCYTE_COMMUNICATION | MSigDB lists | GO_BUNDLE_OF_HIS_CELL_TO_PURKINJE_MYOCYTE_COMMUNICATION | 11 | 4 | 17377 | 1707 |
PKP2,SCN5A,DSP,DSG2 |
| 1.741e-02 | -4.05 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | MSigDB lists | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | 11 | 4 | 17377 | 1707 |
TJP1,DSP,DSG2,OCLN |
| 1.741e-02 | -4.05 | GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION | MSigDB lists | GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION | 11 | 4 | 17377 | 1707 |
MSX1,HEYL,SNAI2,HEY1 |
| 1.741e-02 | -4.05 | GO_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE | MSigDB lists | GO_RESPONSE_TO_FOLLICLE_STIMULATING_HORMONE | 11 | 4 | 17377 | 1707 |
TGFBR3,ASNS,HMGCS1,PPARGC1A |
| 1.741e-02 | -4.05 | IIZUKA_LIVER_CANCER_EARLY_RECURRENCE | MSigDB lists | IIZUKA_LIVER_CANCER_EARLY_RECURRENCE | 11 | 4 | 17377 | 1707 |
SGK1,VIM,REL,MEF2C |
| 1.741e-02 | -4.05 | GO_PROTEIN_BINDING_INVOLVED_IN_CELL_CELL_ADHESION | MSigDB lists | GO_PROTEIN_BINDING_INVOLVED_IN_CELL_CELL_ADHESION | 11 | 4 | 17377 | 1707 |
PKP2,EPCAM,DSP,DSG2 |
| 1.741e-02 | -4.05 | KRISHNAN_FURIN_TARGETS_DN | MSigDB lists | KRISHNAN_FURIN_TARGETS_DN | 11 | 4 | 17377 | 1707 |
OPLAH,ADAMTS6,TSPAN9,LEPR |
| 1.741e-02 | -4.05 | RHOGAP | prosite domains | PS50238 | 65 | 13 | 12060 | 1278 |
CHN1,ARHGAP26,ARHGAP21,CHN2,ARAP2,ARHGAP22,OPHN1,SRGAP1,ARHGAP28,ARHGAP32,FAM13A,ARHGAP44,SYDE2 |
| 1.741e-02 | -4.05 | TSP1 | prosite domains | PS50092 | 65 | 13 | 12060 | 1278 |
ADAMTS17,UNC5C,ADGRB3,WISP3,ADAMTS3,ISM1,THSD4,THSD7B,ADAMTS6,UNC5B,THSD1,HMCN1,ADGRB2 |
| 1.743e-02 | -4.05 | ECM-receptor interaction | KEGG pathways | hsa04512 | 82 | 15 | 7161 | 730 |
COL9A3,SV2B,ITGB7,COL6A2,FN1,COL4A3,THBS4,COL4A4,ITGA6,ITGA2,ITGB3,LAMB1,LAMC3,COL4A5,COL9A2 |
| 1.743e-02 | -4.05 | ECM-receptor interaction | KEGG pathways | ko04512 | 82 | 15 | 7161 | 730 |
COL9A3,SV2B,ITGB7,COL6A2,FN1,COL4A3,THBS4,COL4A4,ITGA6,ITGA2,ITGB3,LAMB1,LAMC3,COL4A5,COL9A2 |
| 1.744e-02 | -4.05 | Sema | smart domains | SM00630 | 31 | 8 | 9493 | 1056 |
SEMA3C,SEMA6B,MET,SEMA4F,SEMA3A,SEMA6A,SEMA6C,PLXNA2 |
| 1.745e-02 | -4.05 | HELZ (helicase with zinc finger) | protein interactions | 9931 | 61 | 12 | 17029 | 1718 |
KIAA1671,THSD4,RBFOX2,MYC,ESRP1,GAN,CCNJL,CTBP2,RACK1,SAV1,SMYD3,EYA4 |
| 1.747e-02 | -4.05 | voltage-gated calcium channel complex | cellular component | GO:0005891 | 43 | 9 | 18223 | 1724 |
CACNG3,CACNB2,CACNA1E,CATSPERE,PDE4D,CACNB4,HSPA2,CACNA2D1,NOS1AP |
| 1.747e-02 | -4.05 | RA | pfam domains | PF00788 | 35 | 8 | 17054 | 1666 |
RASSF8,RIN2,ARAP2,GRB14,MYO10,RAPGEF2,GRB10,RADIL |
| 1.751e-02 | -4.04 | Vitamin B5 (pantothenate) metabolism | REACTOME pathways | R-HSA-199220 | 17 | 5 | 10287 | 971 |
VNN2,ENPP1,PANK3,PANK1,FASN |
| 1.751e-02 | -4.04 | Acetylcholine Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-264642 | 17 | 5 | 10287 | 971 |
PPFIA4,SNAP25,UNC13B,STXBP1,PPFIA2 |
| 1.752e-02 | -4.04 | DELACROIX_RAR_BOUND_ES | MSigDB lists | DELACROIX_RAR_BOUND_ES | 430 | 56 | 17377 | 1707 |
FAM171B,TMEM63C,NBL1,INPPL1,DYRK3,FN1,TRIM16,CELSR3,ENAH,CEBPA,SLX1B,ZIC2,FAM198B,ZNF219,LGI2,MOK,ZNF438,ZFYVE28,ZIC5,EBF4,STEAP3,IQGAP3,JAM2,TSPAN9,SPRY2,PDGFRB,GLI1,DUSP1,C3orf67,NDUFA4L2,DISC1,GCA,RIN2,RHOQ,PDK1,NR6A1,PTPN6,STAT4,DUSP9,RNF125,ATF3,SDK1,SNAP25,PLEKHB1,SLC39A14,CD37,HLF,NACC2,PCGF2,HS3ST3B1,BMP4,COBL,FOXA1,DDIT3,MME,PHC1 |
| 1.753e-02 | -4.04 | exocytic vesicle | cellular component | GO:0070382 | 187 | 27 | 18223 | 1724 |
DOC2A,DMXL2,SV2B,SLC40A1,BDNF,RAB3B,SCAMP1,SYT12,VAMP8,LRRK2,SNAP25,RABAC1,APBA1,SNCA,TRIM9,ICA1,UNC13B,RAB26,PTPRS,PTPRN2,SEPT5,SYNGR3,RAB27B,APBA2,CTTNBP2,STON2,MME |
| 1.754e-02 | -4.04 | cell body membrane | cellular component | GO:0044298 | 23 | 6 | 18223 | 1724 |
DAB2IP,AMIGO1,KCNC4,ATP2B1,KCNB2,ATP1A3 |
| 1.754e-02 | -4.04 | neuronal cell body membrane | cellular component | GO:0032809 | 23 | 6 | 18223 | 1724 |
DAB2IP,AMIGO1,KCNC4,ATP2B1,KCNB2,ATP1A3 |
| 1.754e-02 | -4.04 | regulation of smooth muscle cell migration | biological process | GO:0014910 | 79 | 14 | 17256 | 1658 |
PAK1,DOCK7,TERT,ITGA2,PRKG1,BMPR1A,TPM1,PPARGC1A,NRP1,DOCK5,SLIT2,PDGFRB,IGFBP3,MEF2C |
| 1.754e-02 | -4.04 | regulation of protein depolymerization | biological process | GO:1901879 | 79 | 14 | 17256 | 1658 |
GSN,PLEKHH2,FGF13,MAP1A,CKAP2,DSTN,EPS8,ADD2,HDGFL3,TMOD2,ASPH,MID1,MAP1B,SCIN |
| 1.754e-02 | -4.04 | human chr10q26.11 | chromosome location | human chr10q26.11 | 21 | 5 | 26185 | 1967 |
INPP5F,BAG3,CACUL1,SFXN4,RGS10 |
| 1.754e-02 | -4.04 | human chr10q26.2 | chromosome location | human chr10q26.2 | 21 | 5 | 26185 | 1967 |
UROS,DOCK1,FANK1,PTPRE,DHX32 |
| 1.757e-02 | -4.04 | CSPG4 (chondroitin sulfate proteoglycan 4) | protein interactions | 1464 | 16 | 5 | 17029 | 1718 |
GRIP1,TNK2,MPDZ,LGALS3,PCBP4 |
| 1.757e-02 | -4.04 | SELL (selectin L) | protein interactions | 6402 | 16 | 5 | 17029 | 1718 |
PRKCQ,PODXL2,CFH,PRKCA,PRKG1 |
| 1.757e-02 | -4.04 | INHBA (inhibin subunit beta A) | protein interactions | 3624 | 16 | 5 | 17029 | 1718 |
ACVR2A,INHBC,ACVR2B,ACVR1,TGFBR3 |
| 1.757e-02 | -4.04 | PROS1 (protein S) | protein interactions | 5627 | 16 | 5 | 17029 | 1718 |
TYRO3,NPM1,BMP4,TCTN2,C4BPB |
| 1.757e-02 | -4.04 | BCL2A1 (BCL2 related protein A1) | protein interactions | 597 | 16 | 5 | 17029 | 1718 |
BBC3,HRK,PMAIP1,NR4A1,BIK |
| 1.757e-02 | -4.04 | LIN7B (lin-7 homolog B, crumbs cell polarity complex component) | protein interactions | 64130 | 16 | 5 | 17029 | 1718 |
KCNJ4,APBA1,GRIK2,BAIAP2,MPP2 |
| 1.757e-02 | -4.04 | GABRR1 (gamma-aminobutyric acid type A receptor rho1 subunit) | protein interactions | 2569 | 16 | 5 | 17029 | 1718 |
GABRR2,SLC6A9,PRKCA,MAP1B,PRKG1 |
| 1.757e-02 | -4.04 | PTPRM (protein tyrosine phosphatase, receptor type M) | protein interactions | 5797 | 16 | 5 | 17029 | 1718 |
PTPRS,RACK1,CDC42BPA,PPFIBP1,PCSK5 |
| 1.757e-02 | -4.04 | ITGB7 (integrin subunit beta 7) | protein interactions | 3695 | 16 | 5 | 17029 | 1718 |
ITGB7,RACK1,FN1,PRKCB,PRKCD |
| 1.757e-02 | -4.04 | GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1) | protein interactions | 2983 | 16 | 5 | 17029 | 1718 |
LIN7A,UACA,MYCBP2,GUCY1A2,NOS3 |
| 1.757e-02 | -4.04 | GO_GATED_CHANNEL_ACTIVITY | MSigDB lists | GO_GATED_CHANNEL_ACTIVITY | 316 | 43 | 17377 | 1707 |
KCNV1,ANO10,TMEM63C,SCN5A,CACNG3,GRIK2,GABRB2,SCN8A,GABRG2,GABRR2,ITPR2,GAS6,KCNC4,CACNB4,NCS1,KCNJ4,KCNN2,CHRNA5,KCNAB1,SCN1B,CACNB2,KCNMB3,KCNS3,TMEM37,SCN2A,SCN3A,KCNB2,TRPM4,KCNIP3,KCNQ3,KCNH5,CACNA1E,GRID1,CHRNA6,RASA3,RYR2,KCND3,KCNK15,GRIK4,KCNMB4,KCNG1,GRIN2D,CACNA2D1 |
| 1.760e-02 | -4.04 | acetyl-CoA metabolic process | biological process | GO:0006084 | 29 | 7 | 17256 | 1658 |
MVK,HMGCS1,AADAT,AASS,TDO2,MVD,FASN |
| 1.760e-02 | -4.04 | glutamate secretion | biological process | GO:0014047 | 29 | 7 | 17256 | 1658 |
PPFIA4,SNAP25,SLC1A3,UNC13B,APBA1,STXBP1,PPFIA2 |
| 1.760e-02 | -4.04 | regulation of synaptic vesicle transport | biological process | GO:1902803 | 29 | 7 | 17256 | 1658 |
PRKN,SEPT5,UNC13B,PFN2,STXBP1,LRRK2,RIMS2 |
| 1.760e-02 | -4.04 | positive regulation of filopodium assembly | biological process | GO:0051491 | 29 | 7 | 17256 | 1658 |
TENM1,GPM6A,DNM3,RHOQ,RIPOR2,NRP1,FNBP1L |
| 1.760e-02 | -4.04 | TMEM52B (transmembrane protein 52B) | protein interactions | 120939 | 34 | 8 | 17029 | 1718 |
PKP2,CACHD1,BMPR1A,ANKRD13D,MYADM,PTPRD,ATP2B4,NEDD4 |
| 1.760e-02 | -4.04 | TMED6 (transmembrane p24 trafficking protein 6) | protein interactions | 146456 | 34 | 8 | 17029 | 1718 |
ST6GALNAC3,GAS6,CANX,ITPRIP,WLS,ITGA6,LRP12,ITGA2 |
| 1.760e-02 | -4.04 | Tor1aip1 (torsin A interacting protein 1) | protein interactions | 208263 | 34 | 8 | 17029 | 1718 |
SORBS1,FNDC3A,CANX,SLC1A5,C4A,FAAP20,HK2,DYNC2LI1 |
| 1.763e-02 | -4.04 | phospholipid transport | biological process | GO:0015914 | 64 | 12 | 17256 | 1658 |
ATP9A,MFSD2A,ATP8A1,LDLR,OSBPL5,PRELID2,PRELID1,NPC2,ATP11A,PLTP,ATP10D,ABCG1 |
| 1.763e-02 | -4.04 | collagen catabolic process | biological process | GO:0030574 | 64 | 12 | 17256 | 1658 |
MMP15,MRC2,COL6A2,COL4A3,ADAMTS3,COL25A1,COL4A4,COL18A1,COL19A1,PHYKPL,COL4A5,MMP16 |
| 1.763e-02 | -4.04 | Cholinergic synapse | KEGG pathways | hsa04725 | 112 | 19 | 7161 | 730 |
CREB3L2,GNG12,ATF4,KCNQ3,ADCY1,CHRNA6,CREB5,ITPR2,PRKCA,PLCB1,GNAI1,KCNJ4,PRKCB,AKT3,GNAO1,GNB4,ADCY6,CHRM3,PRKACB |
| 1.768e-02 | -4.04 | SFN (stratifin) | protein interactions | 2810 | 266 | 38 | 17029 | 1718 |
RPS20,LONRF1,CGN,MYCBP2,SLK,IPO5,PPFIBP2,PKP2,RHPN2,SPIRE1,RPL34,ABLIM1,RALGPS2,PPFIBP1,RPS11,GAN,KIAA0408,ERRFI1,RPS13,RPL26,PPP1R3D,MARK1,PARD3B,YAP1,CBY1,ARHGAP32,RACK1,SAV1,MAP1B,IRS2,ARHGAP21,KCNK15,RND3,SH3BP4,PIK3C2B,RPL4,MAP3K20,SFN |
| 1.770e-02 | -4.03 | GO_ACTIN_MEDIATED_CELL_CONTRACTION | MSigDB lists | GO_ACTIN_MEDIATED_CELL_CONTRACTION | 70 | 13 | 17377 | 1707 |
EPB41L5,SCN5A,SCN1B,CACNB2,ANK2,FGF12,PKP2,RYR2,VIM,TPM1,NEB,CACNA2D1,GJC1 |
| 1.770e-02 | -4.03 | GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_DN | 164 | 25 | 17377 | 1707 |
ITGB7,RBFOX2,OR51B4,SATB2,PALLD,MLC1,SPINK5,CAMK2N1,CECR2,RAP2A,CHRDL1,DUSP19,BBC3,DAB2IP,TMED9,PAX9,PLD1,RNF130,SLCO4C1,MYO6,RAB27B,TSPAN9,CACNA2D1,PDGFRB,TLL2 |
| 1.770e-02 | -4.03 | GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN | MSigDB lists | GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN | 164 | 25 | 17377 | 1707 |
DMXL2,AVPI1,TCP11L2,PNRC1,ATP8A1,ST6GAL1,ARID5B,ZNF565,EFHC1,ATXN7L1,OTUD1,ZNF827,NSD1,FRY,ZNF354A,FCHO2,RPS11,PELI2,AKT3,BCL6,ZBTB20,MARCKS,TANC2,ATP2B1,DUSP1 |
| 1.770e-02 | -4.03 | MORF_PRKCA | MSigDB lists | MORF_PRKCA | 164 | 25 | 17377 | 1707 |
TNIK,CFH,GABRB2,LRP4,RNF24,CDC42BPA,FAM13A,PRKCA,SLC46A3,FAM110B,COL14A1,GPR19,PPM1E,ITGBL1,MAP2,COL19A1,PDE4D,ST8SIA1,TANC2,MYT1,NR3C2,SMYD3,NEB,CACNA2D1,B4GALT6 |
| 1.770e-02 | -4.03 | GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_UP | MSigDB lists | GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_UP | 164 | 25 | 17377 | 1707 |
SUSD3,ADAL,TUBA1A,PFKFB2,SLC36A1,OPHN1,RASA3,AGAP2,APBA1,ZDHHC14,BAIAP2,PPP2R3A,TXNDC5,MGAT1,PLXDC2,SRD5A3,QPCTL,MARCH3,CNNM2,STEAP3,LMAN2,AGL,BTRC,FES,ATP1A3 |
| 1.771e-02 | -4.03 | GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP | MSigDB lists | GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP | 197 | 29 | 17377 | 1707 |
CXCR5,INPPL1,RHOQ,ALDH2,LGALS3,IL15,EPS8,CYP4V2,LITAF,KCTD12,PDE8A,SCD,GSTO1,CD40,NEDD4,GLCE,EPCAM,MCOLN2,ENTPD1,EBF1,CD37,ARHGAP21,MYADM,MYC,PRKCD,RAB31,MARCKS,LIFR,SYK |
| 1.771e-02 | -4.03 | HALLMARK_INFLAMMATORY_RESPONSE | MSigDB lists | HALLMARK_INFLAMMATORY_RESPONSE | 197 | 29 | 17377 | 1707 |
RGS16,CD55,IL15,LDLR,MSR1,SELL,CALCRL,SLC7A2,CD40,LCP2,IL18R1,PCDH7,F3,DCBLD2,SLC7A1,CXCL10,TLR3,SCN1B,MYC,CSF1,ITGB3,ACVR2A,TNFSF15,MET,PTPRE,KIF1B,RASGRP1,ATP2B1,LAMP3 |
| 1.772e-02 | -4.03 | calcium channel complex | cellular component | GO:0034704 | 65 | 12 | 18223 | 1724 |
CACNG3,CACNB2,CACNA1E,RYR2,CATSPERE,PDE4D,CACNB4,HSPA2,HERPUD1,CACNA2D1,NOS1AP,MCU |
| 1.774e-02 | -4.03 | response to monosaccharide | biological process | GO:0034284 | 151 | 23 | 17256 | 1658 |
PRKAA2,SESN2,COL6A2,ACVR1C,PFKFB2,GAS6,ACVR2B,RACK1,ILDR2,GPLD1,NKX6-1,RAB11FIP5,IRS2,UNC13B,IGF1R,CTSV,ERN1,XBP1,ITGA2,SREBF1,PTPRN2,PPARGC1A,PCK2 |
| 1.774e-02 | -4.03 | EIF4E2 (eukaryotic translation initiation factor 4E family member 2) | protein interactions | 9470 | 144 | 23 | 17029 | 1718 |
CGN,PHLDB2,NECAB2,RASAL2,REL,PTPN13,PLEKHA5,CBY1,LPIN3,FAM110B,HOMER3,NAV1,RALGPS2,EIF4EBP1,P4HA2,MAP3K21,SH3BP4,TANC2,SPRY2,OSBPL6,KIF1B,LARP1,GAB2 |
| 1.781e-02 | -4.03 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | 85 | 15 | 17377 | 1707 |
GALNT3,KLF8,CA2,ISM1,CYP2J2,WLS,TES,CYB5R2,ITGA2,STC2,MAOA,ACTA2,OXTR,NR3C2,PERP |
| 1.784e-02 | -4.03 | DAZARD_RESPONSE_TO_UV_NHEK_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_DN | 299 | 41 | 17377 | 1707 |
CREB3L2,EXPH5,EFNB2,ID1,PRSS12,LDLR,PSD3,CTBP2,ABAT,SATB1,DDIT4,MTUS1,MYC,PRKCD,KLF9,MAST4,RAPGEF5,CEBPD,ATP2B1,TBC1D8,MN1,VEGFC,RIN2,BCL7A,MICAL2,SKAP2,RAPGEF2,ARID5B,VLDLR,WWC1,FERMT2,FNDC3A,DKK1,HEG1,SLC7A1,SMAD3,INSIG1,FAT1,FNBP1L,DOCK9,LPP |
| 1.789e-02 | -4.02 | GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN | 156 | 24 | 17377 | 1707 |
BCL7A,MYCBP2,RNF145,GALNT12,PLEKHA5,CACNA1E,DNAJC3,NPM1,CR2,PDE8A,NEDD4,TRPS1,TMEM154,RPL12,TLR3,PTPRJ,RUNDC3B,MARCKS,PDE4D,TBC1D9,IL9R,IL1RAP,PRKACB,RPS13 |
| 1.789e-02 | -4.02 | GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP | 156 | 24 | 17377 | 1707 |
LANCL3,SLC37A1,KLHL3,RNF144A,FAM131C,DNAJC3,PTPN6,ST6GAL1,PRRG1,PLEKHA1,ATP1B1,SATB1,CCNJ,CHN1,ABLIM1,GYPC,TMPRSS9,DLX2,IPCEF1,ST8SIA1,PJA1,TBC1D4,HS6ST3,RPS13 |
| 1.789e-02 | -4.02 | GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_DN | 156 | 24 | 17377 | 1707 |
PFKFB4,FADS1,MXI1,GAPDH,ENO2,SH2D2A,ATP9A,FHL2,GTF2IRD1,AK4,ATF3,EBF1,RNF150,ALDOC,STARD4,RUNDC3B,P4HA1,BNIP3,TNFSF4,ENO1,TNFRSF11A,CSRP2,PERP,RRAGD |
| 1.795e-02 | -4.02 | GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_DN | MSigDB lists | GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_DN | 116 | 19 | 17377 | 1707 |
SERINC5,AMOTL1,RASAL2,TCP11L2,CAP2,MCOLN3,CALCRL,SEZ6L2,TNKS1BP1,MGMT,MCU,PCDH7,NCAM2,GTSF1,RPS11,LRRIQ3,SERPINI1,ARL4D,PURG |
| 1.795e-02 | -4.02 | GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_DN | MSigDB lists | GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_DN | 116 | 19 | 17377 | 1707 |
BTC,KCNIP3,MARK1,CELSR3,BVES,JPH1,ADCY1,CLSTN2,ACVR2B,ZBBX,KCND3,HECTD2,ARMC4,DSG2,SH3BP4,CLMN,MYOM2,DLG2,SMAD6 |
| 1.795e-02 | -4.02 | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_MEF_LCP_WITH_H3K4ME3 | 116 | 19 | 17377 | 1707 |
BTC,GSTM2,ARHGEF11,CYP2J2,LPIN3,TNKS1BP1,DDR1,WARS,RUFY4,SOAT2,SEC16B,GBP1,DAB2IP,HGF,VWA5A,IQSEC2,SNX10,TLR4,PDGFRB |
| 1.795e-02 | -4.02 | GSE9946_MATURE_STIMULATORY_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN | MSigDB lists | GSE9946_MATURE_STIMULATORY_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_DN | 116 | 19 | 17377 | 1707 |
DISC1,MSX1,RASAL2,TSPAN15,SLC27A2,GABRB2,ANK2,VLDLR,NEO1,GJC1,SYCP2,FAT1,C1QL4,ANKFN1,RAP2A,ADRB1,UNC5B,FNBP1L,XKR4 |
| 1.796e-02 | -4.02 | phospholipid transporter activity | molecular function | GO:0005548 | 56 | 11 | 17224 | 1680 |
PLSCR4,ATP9A,MFSD2A,ATP8A1,OSBPL5,PRELID2,PRELID1,ATP11A,PLTP,ATP10D,ABCG1 |
| 1.802e-02 | -4.02 | YANG_BREAST_CANCER_ESR1_UP | MSigDB lists | YANG_BREAST_CANCER_ESR1_UP | 35 | 8 | 17377 | 1707 |
GSTM3,GATA3,KCNK15,ABAT,TBC1D9,WFS1,XBP1,INPP4B |
| 1.802e-02 | -4.02 | GO_CYCLIC_NUCLEOTIDE_BINDING | MSigDB lists | GO_CYCLIC_NUCLEOTIDE_BINDING | 35 | 8 | 17377 | 1707 |
PRKG2,PRKAR2B,PDE4D,BVES,PDE10A,RAPGEF2,RAPGEF4,PRKG1 |
| 1.802e-02 | -4.02 | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | MSigDB lists | COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_UP | 35 | 8 | 17377 | 1707 |
TYRO3,GPRC5B,ALDOC,SCD,GALNT13,CPE,DNER,PLEKHB1 |
| 1.802e-02 | -4.02 | GO_NEGATIVE_REGULATION_OF_MUSCLE_ORGAN_DEVELOPMENT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MUSCLE_ORGAN_DEVELOPMENT | 35 | 8 | 17377 | 1707 |
SFMBT1,PRICKLE1,USP2,BMP4,SAV1,MSTN,DKK1,TLL2 |
| 1.804e-02 | -4.02 | ATGTTTC,MIR-494 | MSigDB lists | ATGTTTC,MIR-494 | 148 | 23 | 17377 | 1707 |
DBN1,SLITRK2,BMPR2,GRIK2,ELOVL3,PRRG1,ADAMTS6,ZIC2,ATF3,CANX,NOVA1,NAALADL2,DCBLD2,TRPS1,HMGCS1,TACC2,NBEA,PRICKLE2,JAKMIP2,BEND4,WWC2,PPARGC1A,OSBPL6 |
| 1.805e-02 | -4.01 | VEGFA-VEGFR2 Pathway | REACTOME pathways | R-HSA-4420097 | 330 | 43 | 10287 | 971 |
WASF3,BTC,FN1,RASAL2,DUSP8,DOCK1,ITPR2,PRKCA,PRKCD,ITGB3,DAB2IP,NCAM1,MET,GFRA1,RASGRP1,PRKACB,PDGFRB,NOS3,DUSP1,FGFR4,PAK1,IL17RD,VAV3,PXN,SH2D2A,RAPGEF2,DUSP9,RASA3,FGF17,BAIAP2,FGFR1,MAPKAPK2,IRS2,TRIB3,NRG3,NCKAP1L,PRKCB,RASGRF2,AKT3,GRIN2D,HGF,MAPK13,SPRED3 |
| 1.806e-02 | -4.01 | mesenchymal cell differentiation | biological process | GO:0048762 | 143 | 22 | 17256 | 1658 |
EPB41L5,MSX1,ACVR1,WNT11,OVOL2,FGFR1,TGFBR3,EOMES,SEMA4F,HEYL,WWTR1,LRP6,SEMA3C,HGF,BMPR1A,BMP4,NRP1,SEMA3A,SIX2,SNAI2,HEY1,MEF2C |
| 1.806e-02 | -4.01 | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN | MSigDB lists | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN | 189 | 28 | 17377 | 1707 |
TNK2,RIN2,EIF4E3,SKAP2,UBASH3B,ITGA6,RAPGEF4,MCOLN3,CALCRL,RASA3,GABRR2,SLC12A6,F12,TTLL7,SATB1,KBTBD11,TBC1D30,ID3,TECPR1,AKT3,SGK1,HS3ST3B1,CMPK2,PLTP,PTPRE,RASGRP1,PRKACB,MAST1 |
| 1.806e-02 | -4.01 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | 189 | 28 | 17377 | 1707 |
ACVR1,LGALS3,MLF1,PREX1,TTYH2,GATA3,PHACTR2,COTL1,SEL1L3,CRYBG3,HERPUD1,SMAD3,MCOLN2,TIFA,ZBTB38,TGFBR3,PMAIP1,PRKCD,NCOA7,EEPD1,ST8SIA1,FAR2,SNX10,KIF1B,ATP2B1,ATP2B4,LPP,STOM |
| 1.806e-02 | -4.01 | GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_DN | 189 | 28 | 17377 | 1707 |
RWDD2A,GCNT2,USP2,RHOBTB1,SLC39A8,CYP2J2,ST6GAL1,GATA3,SELL,KCTD12,ABAT,SLC1A3,FNDC3A,LCP2,TTC28,GNAI1,RANBP2,TLR3,EIF1,ATRNL1,NXPH4,GRB10,MPDZ,GFI1,IL1RAP,SNX7,B4GALT6,RRAGD |
| 1.806e-02 | -4.01 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_UP | 189 | 28 | 17377 | 1707 |
EFNB2,USP2,PDE1B,PLEKHA5,HOMER2,ST6GALNAC3,NTRK3,CD7,COL14A1,SLCO3A1,TUBB4A,IRS2,ENPP1,RPS6KA2,CA2,SEMA4F,KCNAB1,SLC7A11,SH3GL2,ADCY6,ZBTB20,PPARGC1A,MME,STOM,PCSK6,PHC1,ABCG1,TPT1 |
| 1.806e-02 | -4.01 | GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP | 189 | 28 | 17377 | 1707 |
RIN2,PLBD2,CRIM1,KLHL13,AGPAT4,SPATA6,CYTH3,ELOVL3,EDEM3,RABAC1,CCNG1,TGDS,NDFIP2,RNF44,ATP10D,ZFYVE9,SYDE2,HOMER3,CAMK2N1,KCNAB1,NACC2,PAM,MAOA,LMAN2,TMEM37,SYK,FMNL2,RRAGD |
| 1.806e-02 | -4.01 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN | 189 | 28 | 17377 | 1707 |
CARS,PLA2G4A,FADS1,RIN2,RHOQ,ACSL1,IGFBP6,BLVRB,CTBP2,PHGDH,F3,WARS,CEBPB,RTN1,GBP1,P4HA2,SLC2A6,RAB31,RAI14,KIAA0513,SCRN1,GEM,NRP1,TBC1D9,SNX10,LRP12,CKAP4,FZD1 |
| 1.806e-02 | -4.01 | GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN | MSigDB lists | GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN | 189 | 28 | 17377 | 1707 |
UST,ITGB7,SIDT1,TES,ITGA6,LRP4,ASS1,RASA3,FAM102B,PDE8A,HOPX,ENTPD1,TECPR1,TACC2,AKT3,MATN2,ITGB3,RCN3,ADCY6,SERPINI1,MED7,RPL4,TNFSF4,RRAS2,SLFN5,KIF1B,NEB,SFN |
| 1.806e-02 | -4.01 | GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP | 189 | 28 | 17377 | 1707 |
MOCOS,TSPAN15,BVES,DOCK1,PLEKHA5,TTYH2,MAFB,ATF3,RAB38,TLR6,TNKS1BP1,SLCO3A1,F3,CCNJ,SMAD3,ENTPD1,TMCO3,GRHL1,PLOD2,CSF1,SHF,TSPAN13,HK1,PTPRCAP,NPTXR,DOCK8,RBMS2,GAB2 |
| 1.806e-02 | -4.01 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_UP | 189 | 28 | 17377 | 1707 |
RPL26,RBFOX2,MVD,ST6GAL1,DHCR24,LDLR,FASN,MAFB,GSTO1,CUEDC2,ISYNA1,C3orf70,SFXN3,KIAA1217,INTS6,ZDHHC14,DOCK5,HMGCS1,NCKAP1L,SH3RF1,STARD4,ALDH1L1,RAB31,GSTM3,SQLE,KLF9,PROS1,STOM |
| 1.807e-02 | -4.01 | coreceptor activity | molecular function | GO:0015026 | 42 | 9 | 17224 | 1680 |
GPR15,TGFBR3,PTK7,ITGB3,ACVR2A,LRP6,ROR1,NRP1,GPC6 |
| 1.810e-02 | -4.01 | BOYLAN_MULTIPLE_MYELOMA_C_D_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_D_UP | 124 | 20 | 17377 | 1707 |
BCL7A,TRIM2,EPS8,LRMP,NT5DC2,BCL11A,EBF1,PPM1E,ID3,TIFA,IDI1,BACH2,CECR2,TMEM143,PTPRS,DIRAS1,KLF9,STXBP1,PRKACB,CTH |
| 1.813e-02 | -4.01 | peripheral | COSMIC cancer mutations | peripheral | 56 | 11 | 17385 | 1698 |
SLC7A1,SV2B,CHN2,PLXNA2,NDRG2,ACVR2A,DSEL,TMEM170B,UNC5B,DNAH5,CA8 |
| 1.825e-02 | -4.00 | V$CEBPB_01 | MSigDB lists | V$CEBPB_01 | 248 | 35 | 17377 | 1707 |
PLA2G4A,PDE1B,FLVCR2,TNFSF13B,P2RY1,CHAC1,DOCK3,GDPD5,ZFYVE9,FOXP2,COL25A1,STC2,ACVR2A,MARCKS,FHIT,EPHB6,ERRFI1,ETV1,DUSP1,NDUFA4L2,PPP1R3D,GARS,TUBA1A,CRIM1,SFXN4,BNIP3L,CLN5,PLCB1,ZIC1,ALDOA,KLF5,DLG2,SPRY4,PANK3,DDIT3 |
| 1.826e-02 | -4.00 | cytoplasmic vesicle membrane | cellular component | GO:0030659 | 757 | 89 | 18223 | 1724 |
FRMPD3,DOC2A,DMXL2,CACNG3,SCAMP1,RNF144A,ATP8A1,SYT12,VAMP8,LDLR,MSR1,ITPR2,SNX9,PCDH7,CD53,RND2,UNC13B,SEC16B,ITGB3,RAB26,PACSIN1,RAB27B,SYNGR3,CPE,LAMP3,TNK2,TMEM67,CD55,ABCC4,FZD4,TGFA,WLS,LRRK2,LRMP,RAB38,DSP,SNCA,GABARAPL1,ARHGAP21,PTPRJ,GPRC5B,NCKAP1L,ENTPD7,PAM,AHNAK2,PTPRS,ATG5,ARFGEF3,SV2B,LGALS3,SEC24D,GABRB2,BACE1,GABRG2,SELL,SPIRE1,RAB11FIP5,KCNJ4,KIAA0319,SREBF1,MARCH3,CADPS2,MOXD1,MYO6,SLCO4C1,CKAP4,GPR161,NOS3,SNX7,RAB3B,SLC27A2,HIP1,RYR2,PHACTR2,ATP11A,SNAP25,TLR6,PTPRC,ICA1,SH3GL2,PRCP,RAB31,PTPRN2,PLD1,TBC1D4,KIF1B,MME,SFN,STOM |
| 1.832e-02 | -4.00 | regulation of organelle organization | biological process | GO:0033043 | 1212 | 138 | 17256 | 1658 |
FGF13,GATA3,HDGFL3,NPM1,RAC3,SKI,TUBB4A,ARHGEF10L,ADPRHL1,RND2,PPM1E,PMAIP1,HRK,TMED9,CTTN,SLIT2,NEB,PDGFRB,TBC1D8,TGFA,DSTN,LRRK2,BNIP3L,FEZ1,GNAI1,TRIM9,GSN,INSIG1,WIPF3,MAP2,NCKAP1L,PLK2,MAP9,ARHGAP28,BBC3,TMOD2,TPM1,NRP1,PPARGC1A,TMEFF2,MEF2C,CHMP4C,PRKAA2,CELSR1,RHOBTB1,TBC1D1,FBXO4,STXBP6,JDP2,SORBS3,GPSM2,PFN2,SPIRE1,FHOD3,GATA2,MYC,PRELID1,SREBF1,BNIP3,STXBP1,PAK1,ATP5IF1,RHOQ,TBC1D8B,PLCB1,FAM162A,BAIAP2,TBC1D2,PLEKHH2,DYNC2LI1,HK2,LAPTM4B,CDH2,SFN,EPHA3,BTC,PRKN,ID1,RHOD,TMSB15A,GPR65,ADD2,HECW2,NTRK3,PPP1R9A,TBC1D30,SCIN,TBC1D19,CDC14B,BCL6,MET,SSH3,PHLDB2,FER,TMEM67,MYLK3,EVL,PREX1,PRKCQ,WNT11,TBC1D16,JAM3,CENPV,SNCA,SMAD3,RANBP2,PAM,HGF,ATG5,MID1,TENM1,CKAP2,BIK,EPS8,ARL2,SLX1B,USP30,ARHGAP44,FSD1,MAP1A,EHD3,PRKCD,SH3PXD2B,TBC1D9,GFI1,FES,DUSP1,SYNPO2,MSX1,PXN,ASAP3,MAP1B,NSD1,MYADM,RND3,CTSV,BMP4,TBC1D4 |
| 1.833e-02 | -4.00 | positive regulation of synaptic transmission | biological process | GO:0050806 | 135 | 21 | 17256 | 1658 |
CACNG3,RAB3B,GRIK2,SYT12,SHANK2,CLSTN2,SNAP25,SLC1A3,ABAT,NRXN1,BAIAP2,SNCA,UNC13B,CA2,KMO,PLK2,MPP2,GRIN2D,OXTR,STXBP1,RIMS2 |
| 1.837e-02 | -4.00 | CASTELLANO_NRAS_TARGETS_UP | MSigDB lists | CASTELLANO_NRAS_TARGETS_UP | 63 | 12 | 17377 | 1707 |
AK1,CFH,TMEM43,GBP1,CRIP2,ERCC5,IL13RA1,KCTD12,CCNG1,FNDC3A,PLTP,PERP |
| 1.837e-02 | -4.00 | GO_NEGATIVE_REGULATION_OF_AXONOGENESIS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_AXONOGENESIS | 63 | 12 | 17377 | 1707 |
SEMA6B,SEMA4F,FGF13,DCC,LRP4,SEMA3C,NRP1,SEMA3A,SLIT2,SEMA6A,SEMA6C,BCL11A |
| 1.837e-02 | -4.00 | AMIT_SERUM_RESPONSE_120_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_120_MCF10A | 63 | 12 | 17377 | 1707 |
IRS2,ID3,CDR2L,CXCL10,CD55,ID1,RND3,GBP1,C3orf52,FERMT2,KLF5,DLX2 |
| 1.837e-02 | -4.00 | GO_CARBON_OXYGEN_LYASE_ACTIVITY | MSigDB lists | GO_CARBON_OXYGEN_LYASE_ACTIVITY | 63 | 12 | 17377 | 1707 |
CA2,EHHADH,ENO2,UROS,APLF,ACO1,FASN,CBS,TGDS,CA8,ENO1,CA13 |
| 1.839e-02 | -4.00 | SMAD protein signal transduction | biological process | GO:0060395 | 57 | 11 | 17256 | 1658 |
SMAD3,INHBC,SMAD9,MSTN,APELA,INHBE,VIM,BMP4,MAGI2,BMP6,SKI |
| 1.840e-02 | -4.00 | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | 181 | 27 | 17377 | 1707 |
CREB3L2,ITGB7,KLF8,TES,DNAJC3,LDLR,LITAF,SLC25A28,PDE8A,VIM,NPC2,FNDC3A,SFXN3,FKBP11,CTIF,ATXN7L1,FGR,RPS6KA2,RALGPS2,ABCA5,WFS1,MAGEA3,NXPH4,EPHB6,MAGEA6,PCK2,CRYL1 |
| 1.840e-02 | -4.00 | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 181 | 27 | 17377 | 1707 |
MYO1D,KLF8,TRIM2,ZNF516,TRIM16,FGF13,ATP9A,ZCCHC24,MGST3,MLF1,LRP4,DNAJC6,MCTP2,ARID5B,ATF3,DYNC1I1,CHD5,ATP10D,SLC19A2,SMAD3,CAMK2N1,IFT81,KLF9,CTTN,CDH2,CSRP2,DENND5B |
| 1.840e-02 | -4.00 | GO_SKIN_DEVELOPMENT | MSigDB lists | GO_SKIN_DEVELOPMENT | 181 | 27 | 17377 | 1707 |
EXPH5,PTCH2,BCL11B,INTU,LATS2,CELSR1,LGR4,ST14,SOX21,ITGA6,LRP4,DHCR24,YAP1,SLITRK5,SAV1,PALLD,DDR1,TNFRSF19,DSP,SPINK5,AARS,DKK1,KAZN,FRAS1,ITGA2,ERRFI1,SFN |
| 1.840e-02 | -4.00 | GSE27786_LSK_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_LSK_VS_CD8_TCELL_UP | 181 | 27 | 17377 | 1707 |
CREB3L2,FADS1,MYO1D,VAV3,ST14,MGST3,YPEL2,GTF2IRD1,TMEM47,PIBF1,HSPA12B,GLCE,CCDC120,ARHGAP21,HPS1,CLDN12,MATN2,SLC7A5,TNFRSF1A,BMP1,SGK3,AHNAK2,HK1,IQGAP3,TBC1D4,PTPRE,BOD1 |
| 1.840e-02 | -4.00 | GSE28408_LY6G_POS_VS_NEG_DC_UP | MSigDB lists | GSE28408_LY6G_POS_VS_NEG_DC_UP | 181 | 27 | 17377 | 1707 |
TNIK,PPP1R3D,RGS16,MXI1,KDM5B,RAPGEF2,PSTPIP2,ATF7IP2,CCNG1,CDC42BPA,ATP1B1,PRKCA,CD7,SATB1,SLC46A3,PGAP1,PHLDA2,HERPUD1,GABARAPL1,BAG3,ABCA5,KIAA0355,PCBP4,BDH2,BCL6,GRB10,ABCG1 |
| 1.840e-02 | -4.00 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_UP | 181 | 27 | 17377 | 1707 |
UGT8,PTPN13,SYBU,TUBB4A,GALNT3,MAP1A,SLC7A11,RND3,ZNF214,DACT1,EHD3,GHR,C1orf21,STC2,KCNS3,ATRNL1,MARCH3,PTPRS,TSPAN13,PLD1,NRP1,CDH2,MAST4,PRR16,SMAD6,AMPD1,PKIA |
| 1.845e-02 | -3.99 | V$AP4_Q6 | MSigDB lists | V$AP4_Q6 | 206 | 30 | 17377 | 1707 |
PTCH2,NDUFA4L2,BCL11B,MID2,INPPL1,SORBS1,FGF12,GATA3,PRICKLE1,OBSCN,PRKCQ,CHAC1,RGS7,ABHD4,IKZF2,ID3,ABLIM1,KCNN2,PTK7,CACNB2,FRAS1,RASGRF2,ERN1,CNNM2,PTPRS,LOXL4,TNFSF4,FILIP1,ZNF385A,RAB30 |
| 1.848e-02 | -3.99 | EIF4E_DN | MSigDB lists | EIF4E_DN | 93 | 16 | 17377 | 1707 |
RANBP2,CD55,SCAMP1,ITPRIP,DOCK1,MYO10,CNKSR3,PLEKHA5,ESRP1,NCOA7,SVIL,ARHGAP32,ALPK1,SLC46A3,EPDR1,CYP1B1 |
| 1.852e-02 | -3.99 | positive regulation of programmed cell death | biological process | GO:0043068 | 634 | 77 | 17256 | 1658 |
GRIK2,COL18A1,LILRB1,NTRK3,TIAM2,F3,SCIN,GSDME,TLR3,RPS6KA2,UNC13B,PMAIP1,BCL6,DAB2IP,HRK,FANK1,SLIT2,PDGFRB,IGFBP3,CYP1B1,ATF4,GAPDH,COL4A3,ACVR1C,LRRK2,BNIP3L,PREX1,ATF3,WNT11,CD40,SAV1,ARHGEF26,SNCA,SMAD3,GSN,BEX3,RASGRF2,HPGD,BBC3,TNFSF15,PPARGC1A,MEF2C,LATS2,ARHGEF11,ITGA6,APBB1,BIK,TPD52L1,MCF2L,MYC,PRKCD,PRELID1,TFAP2A,BNIP3,PNMA2,DUSP1,HMGCR,RPL26,VAV3,ATP5IF1,UNC5C,MSX1,RAPGEF2,HIP1,OBSCN,RACK1,FAM162A,GPLD1,ID3,NACC2,ACER2,MAP2K6,BMP4,MAP3K20,SFN,FOXA1,DDIT3 |
| 1.856e-02 | -3.99 | protein-containing complex scaffold activity | molecular function | GO:0032947 | 86 | 15 | 17224 | 1680 |
MPP7,SHANK2,LRRK2,HOMER2,DUSP19,PKP2,WWC1,GRIP1,RACK1,SEPT5,SAV1,WWC2,SEPT3,MAGI2,MAGI3 |
| 1.856e-02 | -3.99 | ELO | prosite domains | PS01188 | 6 | 3 | 12060 | 1278 |
ELOVL4,ELOVL7,ELOVL3 |
| 1.856e-02 | -3.99 | LCCL | prosite domains | PS50820 | 6 | 3 | 12060 | 1278 |
DCBLD1,CRISPLD1,DCBLD2 |
| 1.856e-02 | -3.99 | NC1_IV | prosite domains | PS51403 | 6 | 3 | 12060 | 1278 |
COL4A5,COL4A3,COL4A4 |
| 1.859e-02 | -3.99 | Salivary secretion | KEGG pathways | hsa04970 | 90 | 16 | 7161 | 730 |
ADCY1,ATP1B1,ITPR2,GUCY1A2,PRKCA,PLCB1,PRKCB,ADRB1,PRKG1,ADCY6,PRKG2,ATP2B1,ATP2B4,CHRM3,PRKACB,ATP1A3 |
| 1.859e-02 | -3.99 | Salivary secretion | KEGG pathways | ko04970 | 90 | 16 | 7161 | 730 |
ADCY1,ATP1B1,ITPR2,GUCY1A2,PRKCA,PLCB1,PRKCB,ADRB1,PRKG1,ADCY6,PRKG2,ATP2B1,ATP2B4,CHRM3,PRKACB,ATP1A3 |
| 1.863e-02 | -3.98 | HABP4 (hyaluronan binding protein 4) | protein interactions | 22927 | 28 | 7 | 17029 | 1718 |
VIM,PRKCQ,RACK1,ENO2,PRKCA,PRKCB,PRKCD |
| 1.863e-02 | -3.98 | EPHB4 (EPH receptor B4) | protein interactions | 2050 | 28 | 7 | 17029 | 1718 |
SDC3,EFNB2,EPHB6,TCTN2,LRRIQ1,MME,ZSCAN5A |
| 1.865e-02 | -3.98 | sensory perception of mechanical stimulus | biological process | GO:0050954 | 160 | 24 | 17256 | 1658 |
COL4A3,OTOGL,FZD4,GABRB2,GJB2,HOMER2,ROR1,SLC1A3,HOXA1,PGAP1,FGFR1,EYA4,GSDME,RIPOR2,ZNF354A,PDZD7,WFS1,MARVELD2,ITGA2,MYO3B,TFAP2A,MYO6,SPRY2,SNAI2 |
| 1.866e-02 | -3.98 | synaptic vesicle localization | biological process | GO:0097479 | 103 | 17 | 17256 | 1658 |
DOC2A,DNM3,SYT12,KIF5A,KIF5C,SNAP25,SYT14,PCLO,SNCA,TRIM9,UNC13B,LIN7A,CADPS2,SEPT5,TC2N,RIMS2,SNPH |
| 1.868e-02 | -3.98 | vascular endothelial growth factor receptor signaling pathway | biological process | GO:0048010 | 72 | 13 | 17256 | 1658 |
VEGFC,MAPKAPK2,VAV3,PXN,BMPR2,NCKAP1L,DOCK1,SH2D2A,ITGB3,MAPK13,DAB2IP,NRP1,BAIAP2 |
| 1.868e-02 | -3.98 | amino acid transmembrane transport | biological process | GO:0003333 | 72 | 13 | 17256 | 1658 |
SLC7A1,SLC3A2,SLC6A9,SLC7A11,SLC36A1,SLC7A5,SLC36A4,SLC6A15,SLC1A3,SLC7A2,SLC1A5,SLC16A10,SLC43A1 |
| 1.870e-02 | -3.98 | TGAYRTCA_V$ATF3_Q6 | MSigDB lists | TGAYRTCA_V$ATF3_Q6 | 503 | 64 | 17377 | 1707 |
PHACTR3,AVPI1,ID1,CELSR3,PRSS12,LMCD1,SEZ6L2,CDS1,RND2,CDR2L,SIPA1L2,SPEG,KCNN2,ABI3BP,TACC2,PPFIBP1,SYNGR3,ARL4D,MYT1,GLI1,GAB2,SLC3A2,PNRC1,PTPRU,TES,FGF12,BNIP3L,PNMA6A,PLEKHA1,SGK2,RNF44,GABARAPL1,PDLIM3,GNB4,MAP9,MAOA,ATG5,PPARGC1A,MAPK10,MID1,RAB30,CCDC148,ITPRIP,SLK,TJP1,TNFRSF19,EEF2,NOVA2,FLRT3,TSC22D1,PRICKLE2,KLF9,FIGN,RNF148,IQGAP3,DUSP1,PAK1,QSOX1,SNAP25,MBNL2,SPATA7,MAP1B,PTPRC,GEM |
| 1.870e-02 | -3.98 | human chr8q21.13 | chromosome location | human chr8q21.13 | 37 | 7 | 26185 | 1967 |
CASC9,HNF4G,PKIA,CRISPLD1,HEY1,CHMP4C,ZNF704 |
| 1.870e-02 | -3.98 | DOANE_RESPONSE_TO_ANDROGEN_UP | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_UP | 173 | 26 | 17377 | 1707 |
ARHGAP26,MICAL2,SERINC5,DISC1,NBL1,FARP1,MVK,LGALS3,AKAP5,ST6GAL1,FASN,RNF125,WWC1,MAFB,PRKAR2B,SCD,PLEKHA1,EPHB1,FAM174B,SLC19A2,FKBP11,TSKU,GSTM3,FAR2,COBL,ACSM3 |
| 1.870e-02 | -3.98 | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN | MSigDB lists | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN | 173 | 26 | 17377 | 1707 |
ARHGAP26,ARAP2,FARP1,RUNX2,PNP,SH2D2A,JDP2,VAMP8,PREX1,COBLL1,PRDM1,CHSY1,CD7,SMPDL3B,GALNT3,CXCL10,ZBTB38,PTPRJ,MYADM,EOMES,PMAIP1,ITGA2,TOX,LMAN2,SNX10,PERP |
| 1.871e-02 | -3.98 | regulation of body fluid levels | biological process | GO:0050878 | 505 | 63 | 17256 | 1658 |
TYRO3,BTC,DOCK1,UBASH3B,VAMP8,GATA3,STAT5B,HBE1,ITPR2,GAS6,P2RY1,ABAT,PRKCA,LCP2,DDR1,F3,SLC7A11,GRHL1,GATA2,PRKCD,ITGB3,EHD3,PRKG1,ADCY6,PROS1,MET,TLR4,STXBP1,SYK,PRKACB,DOCK8,CHRM3,ZNF385A,NOS3,HBG2,VAV3,CSN2,PTPN6,ADCY1,PRKCQ,PRKAR2B,F12,ZFPM2,CD40,C4BPB,HEG1,ENTPD1,HPSE,PRKCB,PRCP,WFS1,ATP7B,ITGA2,XBP1,PAM,HK2,OXTR,ATG5,JHY,TRPC3,DOCK6,SFN,DOCK9 |
| 1.872e-02 | -3.98 | regulation of protein processing | biological process | GO:0070613 | 111 | 18 | 17256 | 1658 |
CD55,CFH,C4A,LRRK2,CR2,C1R,F12,CHAC1,GAS1,C4BPB,GSN,CCBE1,CFHR1,MAGEA3,PROS1,SUSD4,ENO1,PRKACB |
| 1.873e-02 | -3.98 | MIKKELSEN_NPC_ICP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_NPC_ICP_WITH_H3K4ME3 | 405 | 53 | 17377 | 1707 |
TBKBP1,ADAL,TCTN2,TRIM16,NSUN6,COL4A5,ADAMTS6,CREB5,SLC12A6,SFXN3,NRXN1,FAM13A,IKZF2,ATXN7L1,SLC7A11,AADAT,BCHE,AKAP7,ALDOC,FLRT3,ADCY6,KIAA0408,MDH1B,VGLL4,ETV1,FKBP14,RBMS2,RIN2,GPM6A,TMEM67,ANK2,CYB5R2,AGPAT4,PANK1,ZNF565,MBNL2,PYCR1,ENTPD1,AK1,PRCP,DYNC2LI1,DUSP19,B3GALT2,RAI14,SERPINI1,PLD1,SPRED3,SUSD4,PPARGC1A,MAPK10,SEMA3A,C8orf48,ZNF235 |
| 1.876e-02 | -3.98 | - | gene3d domains | 1.20.120.550 | 6 | 3 | 8148 | 867 |
ALOX5AP,PTGES,MGST3 |
| 1.876e-02 | -3.98 | - | gene3d domains | 2.170.130.20 | 6 | 3 | 8148 | 867 |
DCBLD1,CRISPLD1,DCBLD2 |
| 1.876e-02 | -3.98 | - | gene3d domains | 2.170.240.10 | 6 | 3 | 8148 | 867 |
COL4A5,COL4A3,COL4A4 |
| 1.876e-02 | -3.98 | FA58C_3 | prosite domains | PS50022 | 21 | 6 | 12060 | 1278 |
CPXM2,NRP1,DDR1,CNTNAP3,DCBLD1,DCBLD2 |
| 1.877e-02 | -3.98 | GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS | 943 | 112 | 17377 | 1707 |
DNM3,ID1,LGR4,FGF13,GATA3,LILRB1,NDRG2,STAT5B,NTRK3,ABAT,PIBF1,SEMA6A,SKI,TLR3,BCL6,DAB2IP,PROS1,PDE4D,WWC2,TLR4,SLIT2,PRKACB,SEMA6C,SNAI2,NKX2-1,EVL,MEIS2,COL4A3,CSN2,ACVR1C,DCC,NKX3-2,WNT11,VIM,SYNJ2BP,F12,SAV1,DOCK5,FGFR1,BCL11A,SMAD3,CXCL10,NRG3,NCKAP1L,PLK2,GBP1,ADRB1,SEMA3C,INPP5F,HGF,DLX2,OXTR,BMPR1A,TNFSF4,NRP1,MEF2C,SEMA6B,FN1,ROBO2,C1QTNF3,BMPR2,REL,UBASH3B,CD276,LRP4,HERC5,CHADL,CUEDC2,GAS6,CHSY1,OVOL2,PFN2,SPINK5,NKX6-1,EFEMP1,RAB11FIP5,CNTN4,SEMA4F,GATA2,MYC,PRKCD,STC2,KIAA0319,HS3ST5,PRKG1,ADCY6,FIG4,ERRFI1,GFI1,GPR161,NOS3,HMGCR,TRPM4,USP2,MSTN,RAPGEF2,WWC1,CALCRL,PRICKLE1,MAFB,ZFPM2,DKK1,ID3,THBS4,MCC,SFMBT1,BMP4,SEMA3A,FOXA1,ATP2B4,DDIT3,TLL2 |
| 1.877e-02 | -3.98 | MORF_RAD51L3 | MSigDB lists | MORF_RAD51L3 | 361 | 48 | 17377 | 1707 |
TNIK,RUNX2,CFH,GABRB2,LRP4,RNF24,IL13RA1,RGS7,PRKCA,FAM13A,NOVA1,TPD52L1,COL14A1,FAM110B,SEMA6A,GPR15,PPM1E,BNIP1,SOAT2,FRY,TACC2,PDE10A,AFF2,COL19A1,LRP6,FIG4,ST8SIA1,PDE4D,MYT1,NEB,B4GALT6,GCA,KLHL23,WISP3,CDC42BPA,SLC46A3,GPR19,PLEKHB1,ZNF266,ITGBL1,MAP2,ITGA2,PTPRS,PAX9,TANC2,NR3C2,SMYD3,CACNA2D1 |
| 1.880e-02 | -3.97 | regulation of mesenchymal cell proliferation | biological process | GO:0010464 | 36 | 8 | 17256 | 1658 |
IRS2,FOXP2,MYC,WNT11,BMP4,BMPR1A,SHOX2,FGFR1 |
| 1.880e-02 | -3.97 | B cell receptor signaling pathway | biological process | GO:0050853 | 36 | 8 | 17256 | 1658 |
PTPRC,VAV3,NCKAP1L,PRKCB,PTPN6,PLEKHA1,SYK,MEF2C |
| 1.881e-02 | -3.97 | motor neuron axon guidance | biological process | GO:0008045 | 23 | 6 | 17256 | 1658 |
KIF5C,CHN1,NRP1,SEMA3A,SLIT2,PLXNA2 |
| 1.881e-02 | -3.97 | benzene-containing compound metabolic process | biological process | GO:0042537 | 23 | 6 | 17256 | 1658 |
GSTM3,GSTM2,AADAT,KMO,TDO2,GSTM4 |
| 1.881e-02 | -3.97 | glycosphingolipid biosynthetic process | biological process | GO:0006688 | 23 | 6 | 17256 | 1658 |
ST6GALNAC3,ST8SIA1,UGT8,B3GALT1,B3GALT2,B4GALT6 |
| 1.881e-02 | -3.97 | regulation of metanephros development | biological process | GO:0072215 | 23 | 6 | 17256 | 1658 |
YAP1,BMP4,FAT4,MYC,WWTR1,PDGFRB |
| 1.881e-02 | -3.97 | positive regulation of epidermal cell differentiation | biological process | GO:0045606 | 23 | 6 | 17256 | 1658 |
PTCH2,BMP4,OVOL2,ATOH1,TRIM16,SFN |
| 1.881e-02 | -3.97 | response to muscle activity | biological process | GO:0014850 | 23 | 6 | 17256 | 1658 |
PRKAA2,RYR2,PPARGC1A,MSTN,ADSSL1,ITGA2 |
| 1.882e-02 | -3.97 | CROMER_METASTASIS_DN | MSigDB lists | CROMER_METASTASIS_DN | 78 | 14 | 17377 | 1707 |
CELSR1,TRIM16,KAZN,ALDOA,RAB31,BMP1,SVIL,KLF5,MAST4,HSPA2,PHLDA2,BAIAP2,SFN,IGSF3 |
| 1.882e-02 | -3.97 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | MSigDB lists | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | 78 | 14 | 17377 | 1707 |
ITGB7,COL4A3,FN1,FBN1,COL4A4,ITGB3,LAMB1,ITGA2,RAPGEF4,COL4A5,JAM2,SYK,JAM3,RASGRP1 |
| 1.884e-02 | -3.97 | iron ion transmembrane transport | biological process | GO:0034755 | 17 | 5 | 17256 | 1658 |
SLC39A14,SLC40A1,SLC25A28,STEAP3,STEAP1 |
| 1.884e-02 | -3.97 | cellular response to sterol | biological process | GO:0036315 | 17 | 5 | 17256 | 1658 |
LRP6,HMGCS1,INSIG1,MLC1,GPLD1 |
| 1.884e-02 | -3.97 | retinal ganglion cell axon guidance | biological process | GO:0031290 | 17 | 5 | 17256 | 1658 |
NRP1,SEMA4F,EPHB1,ROBO2,SLIT2 |
| 1.884e-02 | -3.97 | regulation of cAMP-dependent protein kinase activity | biological process | GO:2000479 | 17 | 5 | 17256 | 1658 |
PRKAR2B,SESN2,RAPGEF2,ATP2B4,PKIA |
| 1.884e-02 | -3.97 | linoleic acid metabolic process | biological process | GO:0043651 | 17 | 5 | 17256 | 1658 |
FADS1,ACSL1,GSTM2,CYP2J2,ELOVL3 |
| 1.885e-02 | -3.97 | LIU_TARGETS_OF_VMYB_VS_CMYB_DN | MSigDB lists | LIU_TARGETS_OF_VMYB_VS_CMYB_DN | 42 | 9 | 17377 | 1707 |
GATA3,MAPKAPK2,KLF5,CHSY1,OXTR,PTPRJ,PALLD,CCNA1,FAM107B |
| 1.885e-02 | -3.97 | GO_GENITALIA_DEVELOPMENT | MSigDB lists | GO_GENITALIA_DEVELOPMENT | 42 | 9 | 17377 | 1707 |
TYRO3,SYCP2,TEX15,LGR4,GJB2,DHCR24,LRP6,HOXD13,BMP6 |
| 1.885e-02 | -3.97 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | MSigDB lists | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | 42 | 9 | 17377 | 1707 |
GNG12,AKAP5,GNB4,RAPGEF4,KCNS3,ADCY6,PRKAR2B,ITPR2,PRKACB |
| 1.885e-02 | -3.97 | MODULE_332 | MSigDB lists | MODULE_332 | 42 | 9 | 17377 | 1707 |
NR4A1,MYC,IPO5,GTF2F2,ERCC5,UCHL3,PIBF1,STK24,ISG20 |
| 1.885e-02 | -3.97 | GO_MONOSACCHARIDE_CATABOLIC_PROCESS | MSigDB lists | GO_MONOSACCHARIDE_CATABOLIC_PROCESS | 56 | 11 | 17377 | 1707 |
PFKFB4,GAPDH,ENO2,FUT9,PFKFB2,ALDOC,ALDOA,HK2,HK1,ENO1,CRYL1 |
| 1.885e-02 | -3.97 | JOHNSTONE_PARVB_TARGETS_1_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_1_DN | 56 | 11 | 17377 | 1707 |
INSIG1,SEC24D,MYO10,FAT1,PHACTR2,LIMCH1,ETV1,LIFR,ATP10D,STEAP1,SLIT2 |
| 1.885e-02 | -3.97 | KANNAN_TP53_TARGETS_UP | MSigDB lists | KANNAN_TP53_TARGETS_UP | 56 | 11 | 17377 | 1707 |
QSOX1,SLC3A2,IGFBP6,PMAIP1,SMTN,BCL6,FHL2,FEZ1,BBC3,ACTA2,ATF3 |
| 1.885e-02 | -3.97 | chr1q25 | MSigDB lists | chr1q25 | 56 | 11 | 17377 | 1707 |
PLA2G4A,RGS16,SEC16B,RASAL2,CACNA1E,C1orf21,EDEM3,KIAA1614,TNFSF4,HMCN1,ATP2B4 |
| 1.885e-02 | -3.97 | GO_EMBRYONIC_PATTERN_SPECIFICATION | MSigDB lists | GO_EMBRYONIC_PATTERN_SPECIFICATION | 56 | 11 | 17377 | 1707 |
SMAD3,EPB41L5,LRP6,SATB2,DISP1,NRP1,SMAD6,SEMA3A,PGAP1,COBL,PCSK6 |
| 1.885e-02 | -3.97 | TTANWNANTGGM_UNKNOWN | MSigDB lists | TTANWNANTGGM_UNKNOWN | 56 | 11 | 17377 | 1707 |
ABLIM1,EOMES,ESRRG,PRDM13,MPPED2,ACVR2A,JAKMIP2,ADAMTS6,PRDM1,IKZF2,OSBPL6 |
| 1.885e-02 | -3.97 | DIRMEIER_LMP1_RESPONSE_LATE_UP | MSigDB lists | DIRMEIER_LMP1_RESPONSE_LATE_UP | 56 | 11 | 17377 | 1707 |
CARS,SLC7A1,GARS,SLC7A5,LITAF,FASN,FEZ1,MARCKS,CD40,BATF,DHCR7 |
| 1.887e-02 | -3.97 | HALLMARK_TNFA_SIGNALING_VIA_NFKB | MSigDB lists | HALLMARK_TNFA_SIGNALING_VIA_NFKB | 198 | 29 | 17377 | 1707 |
PNRC1,NR4A1,REL,LDLR,LITAF,ATF3,PHLDA2,F3,CEBPB,SMAD3,IRS2,MSC,CXCL10,PMEPA1,PLK2,MYC,CSF1,EIF1,SLC2A6,BCL6,TSC22D1,SGK1,MARCKS,KLF9,GEM,PTPRE,ATP2B1,CEBPD,DUSP1 |
| 1.889e-02 | -3.97 | SCN5A (sodium voltage-gated channel alpha subunit 5) | protein interactions | 6331 | 22 | 6 | 17029 | 1718 |
SCN5A,DLG2,SNTB1,NEDD4,PATJ,GAN |
| 1.889e-02 | -3.97 | IMPAD1 (inositol monophosphatase domain containing 1) | protein interactions | 54928 | 22 | 6 | 17029 | 1718 |
UST,TCTN2,PLTP,ENPP6,MCOLN3,TNFSF13B |
| 1.889e-02 | -3.97 | VWA8 (von Willebrand factor A domain containing 8) | protein interactions | 23078 | 22 | 6 | 17029 | 1718 |
IDI1,LCA5,PDK1,LGR4,NUDT12,FOXA1 |
| 1.891e-02 | -3.97 | central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | central_nervous_system-brain-atypical_teratoid-rhabdoid_tumour | 216 | 31 | 17385 | 1698 |
BCL11B,MYCBP2,ELOVL4,ESRP1,GABRB2,GPR65,DCHS1,PREX1,PLXNA2,NPM1,OBSCN,NTRK3,CEBPA,MFSD6,EPHB1,SFXN3,B4GALNT3,FGFR1,TERT,GATA2,CNKSR3,ITGA2,SH3BP4,COL19A1,LIMCH1,MYO6,MET,RCAN3,APBA2,MAGI2,TSHR |
| 1.891e-02 | -3.97 | atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | atypical_teratoid-rhabdoid_tumour | 216 | 31 | 17385 | 1698 |
BCL11B,MYCBP2,ELOVL4,GABRB2,GPR65,ESRP1,DCHS1,PREX1,PLXNA2,NPM1,OBSCN,NTRK3,CEBPA,MFSD6,EPHB1,SFXN3,B4GALNT3,FGFR1,TERT,GATA2,CNKSR3,ITGA2,SH3BP4,COL19A1,LIMCH1,MYO6,RCAN3,MET,APBA2,MAGI2,TSHR |
| 1.892e-02 | -3.97 | human chrXq22.3 | chromosome location | human chrXq22.3 | 29 | 6 | 26185 | 1967 |
MORC4,FRMPD3,COL4A5,MID2,TBC1D8B,NUP62CL |
| 1.892e-02 | -3.97 | human chr10q24.1 | chromosome location | human chr10q24.1 | 29 | 6 | 26185 | 1967 |
ENTPD1,SORBS1,RPL13AP5,PIK3AP1,TLL2,CCNJ |
| 1.892e-02 | -3.97 | human chr13q13.3 | chromosome location | human chr13q13.3 | 29 | 6 | 26185 | 1967 |
NBEA,SOHLH2,SPART,SMAD9,CCNA1,CCDC169 |
| 1.895e-02 | -3.97 | hexose catabolic process | biological process | GO:0019320 | 50 | 10 | 17256 | 1658 |
GAPDH,ENO2,FUT9,PFKFB2,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1 |
| 1.896e-02 | -3.97 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | 630 | 78 | 17377 | 1707 |
PLA2G4A,AASS,RBFOX2,GALNT12,PSTPIP2,LDLR,NPM1,AARS,QPRT,CYP51A1,IDI1,SLC22A17,ALDOC,MAP7,SCRN1,JAKMIP2,PROS1,VWA5A,ENO1,CYP1B1,VNN2,GARS,GAPDH,ABCC4,SKAP2,UROS,MVD,C3orf52,DNAJC6,PRKAR2B,CD40,GNAI1,WARS,SFXN1,INSIG1,ALDOA,INPP4B,HPGD,MAOA,SEMA3C,TPM1,MLLT3,MEF2C,ENO2,CLGN,STXBP6,DHCR24,SCD,GPSM2,INPP1,FAM174B,MECOM,ABLIM1,HMGCS1,MSMO1,BACE2,GATA2,DSG2,LMAN2,CKAP4,HMGCR,FADS1,SLC27A2,ARID5B,FHL2,PLS1,CDC42BPA,DDAH1,FBN1,PLOD2,SLC2A6,LAPTM4B,SQLE,TBC1D4,DHCR7,IL9R,PKIA,STOM |
| 1.898e-02 | -3.96 | GSE14413_UNSTIM_VS_IFNB_STIM_L929_CELLS_UP | MSigDB lists | GSE14413_UNSTIM_VS_IFNB_STIM_L929_CELLS_UP | 101 | 17 | 17377 | 1707 |
FARP1,HMGCS1,TLR3,LGR4,WISP3,SPOCD1,NR4A1,EMILIN2,OTX1,CDC42BPA,FBXO27,FAM81A,JAM2,RAPGEF5,KCNB2,MED12L,TBC1D2 |
| 1.898e-02 | -3.96 | GO_CYTOPLASMIC_SIDE_OF_MEMBRANE | MSigDB lists | GO_CYTOPLASMIC_SIDE_OF_MEMBRANE | 165 | 25 | 17377 | 1707 |
FER,GNG12,TNK2,FARP1,RASAL2,CYTH3,LRRK2,RASA3,FERMT2,CHUK,RGS7,CACNB4,FRK,SNX9,GNAI1,FGR,KCNAB1,MCF2L,GNAO1,DAB2IP,GEM,ERRFI1,SYK,ATP2B1,FES |
| 1.898e-02 | -3.96 | ZMPSTE24 (zinc metallopeptidase STE24) | protein interactions | 10269 | 41 | 9 | 17029 | 1718 |
BAG3,CD55,TCTN2,TMEM43,MGST3,SYNJ2BP,TNFRSF17,GDPD5,MME |
| 1.898e-02 | -3.96 | DOCK8 (dedicator of cytokinesis 8) | protein interactions | 81704 | 41 | 9 | 17029 | 1718 |
MTG1,MOB1B,BAG3,RHOQ,DOCK7,FAM124A,PFKFB2,DOCK6,DOCK8 |
| 1.899e-02 | -3.96 | insulin-like growth factor binding | molecular function | GO:0005520 | 29 | 7 | 17224 | 1680 |
IGF1R,IGFBP6,CRIM1,WISP3,ITGA6,ITGB3,IGFBP3 |
| 1.899e-02 | -3.96 | ligand-gated calcium channel activity | molecular function | GO:0099604 | 29 | 7 | 17224 | 1680 |
RYR2,RASA3,MCOLN2,GRIN2D,ITPR2,JPH1,MCOLN3 |
| 1.899e-02 | -3.96 | WW domain binding | molecular function | GO:0050699 | 29 | 7 | 17224 | 1680 |
TCEAL3,ENAH,TNK2,NDFIP2,PMEPA1,RAPGEF2,LITAF |
| 1.899e-02 | -3.96 | epidermal growth factor receptor binding | molecular function | GO:0005154 | 29 | 7 | 17224 | 1680 |
HIP1,EFEMP1,TNK2,FER,BTC,VAV3,TGFA |
| 1.900e-02 | -3.96 | receptor-mediated endocytosis | biological process | GO:0006898 | 211 | 30 | 17256 | 1658 |
PDLIM7,DNM3,CACNG3,PRSS12,SCART1,LDLR,VLDLR,DNAJC6,MSR1,CALCRL,JCHAIN,HIP1,LILRB1,SNAP25,CANX,SNX9,GRK3,NEDD4,SNCA,ENPP1,FCHO2,RAB31,LRP6,INPP5F,LOXL4,CTTN,FNBP1L,SYK,LRP3,LRP12 |
| 1.900e-02 | -3.96 | regulation of protein polymerization | biological process | GO:0032271 | 211 | 30 | 17256 | 1658 |
PAK1,TENM1,FER,EVL,TMSB15A,EPS8,PREX1,ARL2,ADD2,PFN2,RAC3,PPP1R9A,BAIAP2,SPIRE1,FHOD3,SNCA,SCIN,TUBB4A,GSN,MYADM,WIPF3,NCKAP1L,MAP2,PRKCD,ARHGAP28,TMOD2,CTTN,MET,SLIT2,FES |
| 1.906e-02 | -3.96 | SMIRNOV_RESPONSE_TO_IR_2HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_2HR_UP | 49 | 10 | 17377 | 1707 |
RGS16,SLC7A11,PMAIP1,PLK2,BBC3,SGK1,KLF5,ATF3,SESN1,ZFP36L2 |
| 1.906e-02 | -3.96 | GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | MSigDB lists | GO_REGULATION_OF_SMOOTH_MUSCLE_CELL_MIGRATION | 49 | 10 | 17377 | 1707 |
DOCK7,ITGA2,TPM1,NRP1,PPARGC1A,DOCK5,SLIT2,PDGFRB,IGFBP3,F3 |
| 1.906e-02 | -3.96 | GO_HOMOTYPIC_CELL_CELL_ADHESION | MSigDB lists | GO_HOMOTYPIC_CELL_CELL_ADHESION | 49 | 10 | 17377 | 1707 |
TYRO3,SLC7A11,PTPRU,PTPN6,DSG2,ITGB3,PKP2,GAS6,DSP,STXBP1 |
| 1.906e-02 | -3.96 | ROY_WOUND_BLOOD_VESSEL_UP | MSigDB lists | ROY_WOUND_BLOOD_VESSEL_UP | 49 | 10 | 17377 | 1707 |
CHN1,MSX1,GBP1,TES,RAB31,BMP1,NRP1,SEL1L3,HEG1,STOM |
| 1.906e-02 | -3.96 | PARL (presenilin associated rhomboid like) | protein interactions | 55486 | 11 | 4 | 17029 | 1718 |
SLC7A1,ENAH,RBFOX2,CHST10 |
| 1.906e-02 | -3.96 | GRID2 (glutamate ionotropic receptor delta type subunit 2) | protein interactions | 2895 | 11 | 4 | 17029 | 1718 |
DLG2,MAGI2,GRIK2,EML1 |
| 1.906e-02 | -3.96 | AKAP14 (A-kinase anchoring protein 14) | protein interactions | 158798 | 11 | 4 | 17029 | 1718 |
PRKAR2B,SYNJ2BP,PRKACB,ATP1A3 |
| 1.906e-02 | -3.96 | BMP6 (bone morphogenetic protein 6) | protein interactions | 654 | 11 | 4 | 17029 | 1718 |
ACVR2A,ACVR2B,BMPR1A,BMPR2 |
| 1.906e-02 | -3.96 | WNT16 (Wnt family member 16) | protein interactions | 51384 | 11 | 4 | 17029 | 1718 |
WNT11,CANX,WLS,BCL6 |
| 1.906e-02 | -3.96 | FST (follistatin) | protein interactions | 10468 | 11 | 4 | 17029 | 1718 |
BMPR1A,FN1,BMPR2,INHBE |
| 1.906e-02 | -3.96 | PIANP (PILR alpha associated neural protein) | protein interactions | 196500 | 11 | 4 | 17029 | 1718 |
TCAF2,PTPRD,GALNT12,AKT3 |
| 1.906e-02 | -3.96 | RAPGEF3 (Rap guanine nucleotide exchange factor 3) | protein interactions | 10411 | 11 | 4 | 17029 | 1718 |
RANBP2,MAP1A,RRAS2,RAP2A |
| 1.907e-02 | -3.96 | carbohydrate biosynthetic process | biological process | GO:0016051 | 152 | 23 | 17256 | 1658 |
GAPDH,B3GALT1,ATF4,ENO2,GALNT12,GALNT6,ATF3,GALNT13,GALNT17,ISYNA1,GALNT14,CHST10,GALNT3,GALNT1,ALDOC,ALDOA,B3GALT2,PGM2L1,PCK2,PPARGC1A,ENO1,GALNT18,AGL |
| 1.908e-02 | -3.96 | marginal_zone_lymphoma | COSMIC cancer mutations | marginal_zone_lymphoma | 337 | 45 | 17385 | 1698 |
ARHGAP26,CCDC148,AMOTL1,SORBS1,ROBO2,PTPRD,KIF5A,ADSSL1,DDX60L,COL27A1,FHOD3,TXNRD3,GALNT1,PDZD8,TACC2,GAS2L3,BCL6,LRP6,ADCY6,PLTP,GPR161,PRKACB,CDH26,PCDH10,BCL7A,MEIS2,EIF4E3,SLITRK2,DCDC1,PARD3B,CACNA1E,OBSCN,AK4,PHACTR2,SDK1,CRYBG3,EML1,TEX15,FAT4,PELI2,FAT1,HPGD,HGF,DISP1,CACNA2D1 |
| 1.910e-02 | -3.96 | MFS | prosite domains | PS50850 | 94 | 17 | 12060 | 1278 |
SV2B,SLC37A1,FLVCR2,SLC2A13,SPNS1,SLC22A17,MFSD9,SLC16A2,SLC22A18,SLC2A6,SLCO5A1,SLC18B1,SLC16A9,SLC2A12,SLC22A15,SLCO4C1,SLC16A10 |
| 1.914e-02 | -3.96 | FERM_N | pfam domains | PF09379 | 29 | 7 | 17054 | 1666 |
EPB41L5,EPB41L3,FARP1,TLN2,PTPN13,FRMD5,PTPN21 |
| 1.914e-02 | -3.96 | PTPN14 (protein tyrosine phosphatase, non-receptor type 14) | protein interactions | 5784 | 91 | 16 | 17029 | 1718 |
MOB1B,PDLIM7,CGN,LATS2,YAP1,HECW2,WWC1,NPM1,TJP1,CBY1,SAV1,CTNNA2,MAGI3,BAG3,MYC,WWC2 |
| 1.915e-02 | -3.96 | negative regulation of response to endoplasmic reticulum stress | biological process | GO:1903573 | 43 | 9 | 17256 | 1658 |
PRKN,WFS1,DNAJC3,LRRK2,MAGEA3,XBP1,UBAC2,RACK1,HERPUD1 |
| 1.919e-02 | -3.95 | GO_CELLULAR_RESPONSE_TO_PEPTIDE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_PEPTIDE | 266 | 37 | 17377 | 1707 |
GNG12,SORBS1,ID1,ATP6V1E2,ASS1,STAT5B,NKX6-1,CA2,IGF1R,PRKCD,GHR,SREBF1,ADCY6,ERRFI1,PRKACB,FZD1,PAK1,FER,PXN,RHOQ,NR4A1,VLDLR,ADCY1,PRKAR2B,BAIAP2,CPEB1,GPLD1,IRS2,ENPP1,TRIB3,FBN1,GNB4,EIF4EBP1,XBP1,RAB31,GRB10,TBC1D4 |
| 1.920e-02 | -3.95 | Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-112310 | 51 | 10 | 10287 | 971 |
UNC13B,PPFIA2,MAOA,LIN7A,PPFIA4,ABAT,SNAP25,SLC1A3,APBA1,STXBP1 |
| 1.924e-02 | -3.95 | TNFs bind their physiological receptors | REACTOME pathways | R-HSA-5669034 | 30 | 7 | 10287 | 971 |
TNFSF15,EDA,TNFRSF17,EDA2R,TNFSF4,TNFRSF1A,TNFSF13B |
| 1.924e-02 | -3.95 | Interaction between L1 and Ankyrins | REACTOME pathways | R-HSA-445095 | 30 | 7 | 10287 | 971 |
SCN5A,SCN2A,KCNQ3,SCN1B,ANK2,SCN8A,SCN3A |
| 1.925e-02 | -3.95 | Endoderm Differentiation | WikiPathways | WP2853 | 145 | 24 | 5312 | 569 |
EPB41L5,VAV3,FOXN3,SOX21,WWC1,CTBP2,RAB38,TAF4B,SESN1,HOXA1,DKK1,SMAD3,DDAH1,TCF7L1,EOMES,ZIC5,RGS10,SFMBT1,TOX,SLC2A12,PAX9,BMPR1A,FOXA1,NKX2-1 |
| 1.926e-02 | -3.95 | G_PROTEIN_RECEP_F2_4 | prosite domains | PS50261 | 59 | 12 | 12060 | 1278 |
ADGRB3,CELSR1,FZD4,CELSR3,FZD8,ADGRL1,CALCRL,ADGRA3,ADGRG6,ADGRL2,ADGRB2,FZD1 |
| 1.927e-02 | -3.95 | GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_DN | MSigDB lists | GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_DN | 190 | 28 | 17377 | 1707 |
USP2,MPP1,CRIP2,MAFB,TLR6,SNX9,DSP,MAP1B,SKI,SPNS1,FKBP9,CACHD1,IFT81,KCNJ4,SLC22A17,GATA2,MYC,OSBPL5,GSTM3,LRP6,PLD1,CTTN,POU2F2,NRP1,PLTP,PDGFRB,CRYL1,LPP |
| 1.927e-02 | -3.95 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP | 190 | 28 | 17377 | 1707 |
VNN2,BCL7A,GPM6A,SLC27A2,RHOBTB1,TBC1D1,TES,ZCCHC24,PTPN6,PTPN21,LRMP,TJP1,ROR1,RARRES2,GRK6,TUBB4A,TRIM9,PLAGL1,KMO,KIAA0355,CCNA1,MARCKS,TNFRSF17,NKX2-8,AGL,RAPGEF5,RASGRP1,PKIA |
| 1.927e-02 | -3.95 | GSE42021_TREG_VS_TCONV_PLN_UP | MSigDB lists | GSE42021_TREG_VS_TCONV_PLN_UP | 190 | 28 | 17377 | 1707 |
MSX1,PLSCR4,CFH,BMPR2,IL15,GALNT12,LDLR,HERC5,C1R,SLC25A28,ATF3,SPATS2L,HERC6,PCLO,BATF3,WARS,HEG1,ISG20,CXCL10,TYMP,TLR3,PMAIP1,GBP1,CSF1,HK1,SP140L,CEBPD,LAMP3 |
| 1.927e-02 | -3.95 | GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_UP | 190 | 28 | 17377 | 1707 |
CREB3L2,EIF4E3,GCNT2,TCTN2,NR6A1,FZD4,PPFIBP2,NDRG2,IL13RA1,OVOL2,C3orf70,SAV1,CANX,JAM3,HERPUD1,WARS,GJC1,MAPKAPK2,ADCK1,FBN1,KMO,CCNA1,HK2,TMOD2,KLF9,RRAS2,TC2N,CNTN1 |
| 1.927e-02 | -3.95 | GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | 190 | 28 | 17377 | 1707 |
MYO1D,SLC3A2,AVPI1,FLVCR2,SH2D2A,GPR65,UBASH3B,HOMER2,IL13RA1,ATF3,PRKCA,NDFIP2,CENPV,NEO1,F3,TRPS1,SLC7A1,RND2,RPS6KA2,PLAGL1,GRHL1,CDC14B,RBPMS2,EMILIN2,PACSIN1,GFI1,JAM2,PTGES |
| 1.927e-02 | -3.95 | GSE22886_NAIVE_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NKCELL_DN | 190 | 28 | 17377 | 1707 |
CREB3L2,MTG1,PPP1R3D,ARAP2,RHOQ,SH2D2A,CRIM1,ZCCHC24,MCF2L2,MCTP2,CTBP2,ATP1B1,INTS6,INPP1,IL18R1,ATP10D,HEG1,GALNT3,PTPRC,GSN,TNFRSF1A,TOX,CERS4,NCAM1,SLCO4C1,PTPRE,ZNF701,CEBPD |
| 1.927e-02 | -3.95 | GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_UP | 190 | 28 | 17377 | 1707 |
DOC2A,RASAL2,CLGN,KLHL13,DNAJC3,FGF17,LPIN3,SESN1,FAM162A,MAP1B,FAM131B,SNCA,HTR7,EFEMP1,IL17D,RALGPS2,ITGBL1,CCNA1,POF1B,CNNM2,TSPAN12,LRRK1,ATG5,DNAH5,GLIS1,POU3F3,FOXA1,HRASLS |
| 1.927e-02 | -3.95 | GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_DN | MSigDB lists | GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_DN | 190 | 28 | 17377 | 1707 |
TNK2,RIN2,SKAP2,UBASH3B,ITGA6,RAPGEF4,CALCRL,RASA3,GABRR2,F12,TTLL7,KBTBD11,TBC1D30,GALNT3,ID3,TECPR1,SEMA4F,AKT3,SGK1,HS3ST3B1,PLTP,SLFN5,PTPRE,KIF1B,RASGRP1,SFN,PRKACB,MAST1 |
| 1.927e-02 | -3.95 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN | 190 | 28 | 17377 | 1707 |
CD55,ACVR1,SEC24D,RNF144A,FBXO4,ARL15,YAP1,AK4,CHSY1,BATF,SATB1,IL18R1,STEAP1,CD53,SNCA,WARS,SLC39A14,CXCL10,NACC2,XBP1,EIF1,HK1,NRP1,SLC1A5,RRAS2,FES,ATP2B4,PCSK5 |
| 1.927e-02 | -3.95 | negative regulation of cell proliferation | biological process | GO:0008285 | 738 | 88 | 17256 | 1658 |
IL15,COL18A1,LILRB1,GATA3,NPM1,NDRG2,CTBP2,CEBPA,DDR1,SKI,SCIN,GSDME,RIDA,SPEG,PLPP1,RPS6KA2,TGFBR3,FABP6,BCL6,DAB2IP,SNAI2,IGFBP3,CYP1B1,INTU,SKAP2,COL4A3,ACVR1C,PTPRU,PTPN6,TES,WNT11,SYNJ2BP,SAV1,ASPH,FRK,WARS,CAMK2N1,SMAD3,PTPRJ,PEMT,TPM1,PPARGC1A,MAGI2,MEF2C,BCL11B,TENM1,INPPL1,MXI1,IGFBP6,BMPR2,FBXO4,DHCR24,OVOL2,PKN1,EPHB1,CHD5,BCHE,GATA2,MYC,C1QL4,TFAP2A,PRKG1,KLF9,SMAD6,SPRY2,NOS3,PAK1,VEGFC,ATP5IF1,MSX1,MSTN,RAPGEF2,PRDM1,GPLD1,CEBPB,DDAH1,NACC2,TERT,CTSV,SH3BP4,MCC,CLMN,BMP4,NKX2-8,PTGES,TESC,B4GALT7,SFN |
| 1.929e-02 | -3.95 | V$GFI1_01 | MSigDB lists | V$GFI1_01 | 249 | 35 | 17377 | 1707 |
MPZL3,PHACTR3,CGN,CACNG3,MSR1,CREB5,GRK6,SP8,FOXP2,CACNB2,ZNF521,BCL6,PDE4D,NCAM1,C15orf41,BDNF,RAB6B,KLHL3,AGPAT4,PANK1,NFIA,ZFPM2,SGK2,ZIC1,EBF1,KLF12,WDR19,CLMN,DLG2,SH3BGRL2,ZBTB20,BMP4,PPARGC1A,NKX2-8,MEF2C |
| 1.930e-02 | -3.95 | skin-abdomen-malignant_melanoma | COSMIC cancer mutations | skin-abdomen-malignant_melanoma | 408 | 53 | 17385 | 1698 |
BTC,SCN5A,PCDH18,WDR17,IL32,ROBO2,CFH,PTPRD,RECK,LDLR,PTPN21,MCOLN3,GABRG2,EPHB1,SATB1,SPINK5,ZFYVE9,PPP2R3A,NELL2,PIK3AP1,FUT9,ALDH1L1,MET,IQGAP3,PTPRE,DNAH5,SMAD6,SCN3A,CHRM3,FER,ABCC4,DCC,PTPN13,MEF2B,TNS1,SNAP25,B4GALNT3,KHDRBS2,DSP,TMEM74,CTIF,TMEM132B,PTPRC,ARMC4,NAP1L5,PTPRJ,SH3GL2,POPDC3,PTK7,WWTR1,PTPRS,PTPRN2,STON2 |
| 1.932e-02 | -3.95 | TESK2 (testis associated actin remodelling kinase 2) | protein interactions | 10420 | 69 | 13 | 17029 | 1718 |
CGN,PHLDB2,NAV1,RASAL2,DSTN,PLEKHA5,SH3BP4,MAP3K21,CBY1,LPIN3,FAM110B,LARP1,GAB2 |
| 1.934e-02 | -3.95 | GPS | prosite domains | PS50221 | 33 | 8 | 12060 | 1278 |
ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRG6,ADGRL2,ADGRB2,ADGRL1 |
| 1.935e-02 | -3.95 | Volt_channel_dom_sf | interpro domains | IPR027359 | 71 | 13 | 18492 | 1811 |
KCNV1,SCN5A,SLC9C1,CACNA1E,SCN8A,KCNH5,KCNG1,KCNS3,KCND3,SCN2A,KCNC4,SCN3A,KCNB2 |
| 1.936e-02 | -3.94 | vesicle membrane | cellular component | GO:0012506 | 778 | 91 | 18223 | 1724 |
FRMPD3,DOC2A,DMXL2,CACNG3,SCAMP1,RNF144A,ATP8A1,SYT12,VAMP8,LDLR,MSR1,ITPR2,SNX9,PCDH7,CD53,RND2,UNC13B,SEC16B,ITGB3,RAB26,PACSIN1,RAB27B,SYNGR3,CPE,LAMP3,TNK2,TMEM67,CD55,ABCC4,FZD4,TGFA,WLS,LRRK2,LRMP,RAB38,DSP,SNCA,GABARAPL1,ARHGAP21,PTPRJ,GPRC5B,NCKAP1L,ENTPD7,GBP1,PAM,AHNAK2,PTPRS,ATG5,ARFGEF3,SV2B,LGALS3,SEC24D,GABRB2,BACE1,GABRG2,SELL,SPIRE1,RAB11FIP5,KCNJ4,KIAA0319,SREBF1,MARCH3,CADPS2,MOXD1,MYO6,SLCO4C1,CKAP4,GPR161,NOS3,SNX7,RAB3B,SLC27A2,HIP1,RYR2,PHACTR2,ATP11A,SNAP25,FNDC3A,TLR6,PTPRC,ICA1,SH3GL2,PRCP,RAB31,PTPRN2,PLD1,TBC1D4,KIF1B,MME,SFN,STOM |
| 1.939e-02 | -3.94 | FERM_N | interpro domains | IPR018979 | 29 | 7 | 18492 | 1811 |
EPB41L5,EPB41L3,FARP1,TLN2,PTPN13,FRMD5,PTPN21 |
| 1.939e-02 | -3.94 | BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING | 486 | 62 | 17377 | 1707 |
CREB3L2,NBL1,LPAR2,SCAMP1,PTPRD,RECK,ZCCHC24,EPS8,PSD3,STAT5B,GRK6,EFEMP1,EPB41L3,TYMP,RPS6KA2,KCNAB1,AKAP7,TRPC1,LIMCH1,GULP1,JAM2,FKBP14,GATM,SYK,SNAI2,HMGCR,IGFBP3,DCHS1,EDEM3,ACO1,BNIP3L,PACSIN3,FEZ1,PHACTR2,PDE8A,RARRES2,TMEM47,FNDC3A,SESN1,JAM3,LEPR,SPATA7,BAIAP2,SMPDL3B,HOMER3,GNAI1,CAMK2N1,RANBP2,FAT4,CSF1,WFS1,RAI14,PAM,PTPRS,MAOA,PTPRN2,SEMA3C,THAP10,NKX2-8,STOM,MEF2C,ZNF235 |
| 1.941e-02 | -3.94 | GSE45365_NK_CELL_VS_CD8_TCELL_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD8_TCELL_UP | 149 | 23 | 17377 | 1707 |
ANO10,CARD6,RUNX2,TCP11L2,BMPR2,PTPN6,LITAF,SETBP1,ATP1B1,RASSF8,PTPRJ,MSMO1,BHLHA15,GPR155,FAM114A2,LMAN2,PACSIN1,LIFR,FMNL2,LPP,HACE1,TBC1D8,GAB2 |
| 1.941e-02 | -3.94 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING | 149 | 23 | 17377 | 1707 |
TYRO3,PHLDB2,MVK,C1QTNF3,UBASH3B,CD276,TNFAIP8L2,GATA3,CALCRL,CUEDC2,ABAT,F12,SMPDL3B,SMAD3,PRKCD,PRKG1,TNFRSF1A,HGF,INPP5F,PROS1,SLIT2,NOS3,HMGCR |
| 1.941e-02 | -3.94 | GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_UP | MSigDB lists | GSE25677_MPL_VS_MPL_AND_R848_STIM_BCELL_UP | 149 | 23 | 17377 | 1707 |
MOB1B,ITGB7,KLF8,CD55,SKAP2,TBC1D8B,TMEM65,LRRK2,GSTO1,ATP10D,NCS1,RERE,RND2,SLC30A4,TRIM34,KMO,RASGRF2,XBP1,BCL6,SFMBT1,IL9R,ATP2B1,BTRC |
| 1.941e-02 | -3.94 | LU_AGING_BRAIN_DN | MSigDB lists | LU_AGING_BRAIN_DN | 149 | 23 | 17377 | 1707 |
PAK1,UROS,FGF13,ATP8A1,CAP2,ANK2,FGF12,NRXN1,DYNC1I1,MBNL2,FOXG1,MAP1B,BCL11A,PPM1E,PRKCB,MAP2,CACNB2,RAP2A,PDE4D,KIF1B,PANK3,CNTN1,MEF2C |
| 1.943e-02 | -3.94 | GO_REGULATION_OF_RESPONSE_TO_WOUNDING | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_WOUNDING | 397 | 52 | 17377 | 1707 |
TYRO3,PLA2G4A,MVK,C1QTNF3,CFH,IL15,C4A,UBASH3B,CD276,VAMP8,TNFAIP8L2,GATA3,STAT5B,NTRK3,CUEDC2,SLC7A2,ABAT,PRKCA,STK24,F3,HOPX,TLR3,PIK3AP1,PRKCD,BCL6,PRKG1,PROS1,TLR4,TNFRSF11A,SYK,SLIT2,NOS3,HMGCR,PHLDB2,CD55,CALCRL,PRKCQ,F12,C4BPB,SMPDL3B,SMAD3,GSN,GPRC5B,HPSE,ITGA2,TNFRSF1A,INPP5F,HGF,MAPK13,TNFSF4,SUSD4,TC2N |
| 1.944e-02 | -3.94 | positive regulation of axonogenesis | biological process | GO:0050772 | 80 | 14 | 17256 | 1658 |
PAK1,RND2,BDNF,FN1,ROBO2,BMPR2,PLXNA2,NTRK3,AMIGO1,NRP1,SHOX2,SLIT2,SHTN1,MAP1B |
| 1.944e-02 | -3.94 | artery development | biological process | GO:0060840 | 80 | 14 | 17256 | 1658 |
BMPR2,HPGD,PRICKLE1,WNT11,ADAMTS6,PRDM1,ACVR2B,BMPR1A,BMP4,NRP1,SMAD6,HOXA1,PDGFRB,HEY1 |
| 1.944e-02 | -3.94 | collagen metabolic process | biological process | GO:0032963 | 80 | 14 | 17256 | 1658 |
MMP15,ID1,MRC2,COL6A2,COL4A3,ADAMTS3,COL25A1,COL4A4,COL18A1,COL19A1,PHYKPL,COL4A5,SERPINH1,MMP16 |
| 1.945e-02 | -3.94 | meninges | COSMIC cancer mutations | meninges | 525 | 66 | 17385 | 1698 |
TFCP2L1,CGN,CFH,MYO1B,PLXNA2,NPM1,CTBP2,NTRK3,ITPR2,PCLO,HMCN1,HECTD2,COL22A1,RPS6KA2,TACC2,DLX6,KAZN,DAB2IP,MET,DNAH5,ETV1,CYP1B1,SLC3A2,RNF145,ACVR1C,SPOCD1,NFIA,CR2,PAGE5,CRYBG3,FGFR1,HTR7,IRS2,PTK7,ATP7B,TMPRSS9,PTPRS,DISP1,TANC2,BCL11B,SLC6A9,EDA2R,C1QTNF3,CLGN,ITPRIP,PLAG1,FOXP2,LRRN1,EEF2,SLC7A11,TOX,MOXD1,RIMS2,PTCH2,MYO10,SLC36A1,CYTH3,RAPGEF4,GRID1,OBSCN,TTC30A,AGAP2,MMP15,PLOD2,TERT,MYOM2 |
| 1.945e-02 | -3.94 | meningioma | COSMIC cancer mutations | meningioma | 525 | 66 | 17385 | 1698 |
TFCP2L1,CGN,CFH,MYO1B,PLXNA2,NPM1,CTBP2,NTRK3,ITPR2,PCLO,HMCN1,HECTD2,COL22A1,RPS6KA2,TACC2,DLX6,KAZN,DAB2IP,MET,DNAH5,ETV1,CYP1B1,SLC3A2,RNF145,ACVR1C,SPOCD1,NFIA,CR2,PAGE5,CRYBG3,FGFR1,HTR7,IRS2,PTK7,ATP7B,TMPRSS9,PTPRS,DISP1,TANC2,BCL11B,SLC6A9,EDA2R,C1QTNF3,CLGN,ITPRIP,PLAG1,FOXP2,LRRN1,EEF2,SLC7A11,TOX,MOXD1,RIMS2,PTCH2,MYO10,SLC36A1,CYTH3,RAPGEF4,GRID1,OBSCN,TTC30A,AGAP2,MMP15,PLOD2,TERT,MYOM2 |
| 1.957e-02 | -3.93 | alcohol metabolic process | biological process | GO:0006066 | 281 | 38 | 17256 | 1658 |
PRKAA2,NUDT10,MVK,INPPL1,LDLR,DHCR24,CEBPA,ISYNA1,INPP1,CYP51A1,IDI1,ERG28,HMGCS1,SOAT2,MSMO1,SREBF1,PCK2,MOXD1,HMGCR,CYP1B1,ALDH2,MVD,GDPD1,VLDLR,NFE2L1,NPC2,PLCB1,LEPR,LRAT,FGFR1,INSIG1,ACER2,SRD5A3,OSBPL5,INPP4B,SQLE,DHCR7,ABCG1 |
| 1.964e-02 | -3.93 | cellular response to nutrient levels | biological process | GO:0031669 | 203 | 29 | 17256 | 1658 |
PRKAA2,TRPM4,FADS1,GDAP1,SESN2,ATF4,BMPR2,IL15,LRRK2,NUAK2,MARS,ATF3,GAS6,SESN1,STK24,BAIAP2,GABARAPL1,ASNS,PMAIP1,BHLHA15,CTSV,XBP1,SREBF1,PIK3C2B,CADPS2,ATG5,ATP2B1,RRAGD,RNF152 |
| 1.965e-02 | -3.93 | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP | MSigDB lists | GSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP | 182 | 27 | 17377 | 1707 |
KLF8,UGT8,PLSCR4,KDM5B,SEC24D,ANK2,PLAG1,XYLT1,CEBPA,EXOG,SESN1,NUP62CL,C4BPB,TBC1D19,BACH2,ITGBL1,BDH2,RAB31,TSPAN12,HOXD13,HRK,TMED9,TPM1,RAB27B,MLLT3,SLIT2,SFN |
| 1.965e-02 | -3.93 | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN | MSigDB lists | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_DN | 182 | 27 | 17377 | 1707 |
UST,TRDMT1,MTG1,ALDH2,PDE1B,ITGA6,SLC25A27,RASA3,KCTD12,CUEDC2,SEZ6L2,TBC1D16,HOXA1,QPRT,TXNRD3,TECPR1,CA2,TACC2,RASGRF2,PEMT,AKT3,ADCY6,RCN3,TANC2,RASGRP1,SFN,ZNF629 |
| 1.965e-02 | -3.93 | GSE13522_CTRL_VS_T_CRUZI_G_STRAIN_INF_SKIN_UP | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_G_STRAIN_INF_SKIN_UP | 182 | 27 | 17377 | 1707 |
ANTXR2,ACSL1,SCAMP1,TMEM65,PSTPIP2,KIF5C,ADAMTS6,UCHL3,LCP2,IKZF2,GABARAPL1,ENTPD1,TMEM154,PLAGL1,RNF217,AADAT,MYC,PCGF2,PAM,SLC22A15,PROS1,NRP1,TBC1D4,ATP2B1,SMPDL3A,RRAGD,HEY1 |
| 1.965e-02 | -3.93 | GSE22886_NAIVE_CD8_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_UP | 182 | 27 | 17377 | 1707 |
BCL11B,VNN2,SIDT1,IL32,ATP8A1,PRKCQ,STAT5B,CCNG1,RABAC1,CD7,PLEKHB1,HOPX,BACH2,IKZF5,RPL28,EEF2,GYPC,ALDOC,INPP4B,IPCEF1,PTPRCAP,RRAS2,TBC1D4,NR3C2,MLLT3,DUSP1,DOCK9 |
| 1.965e-02 | -3.93 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP | 182 | 27 | 17377 | 1707 |
BCL11B,MYCBP2,CARD6,ANKRD13D,ADAL,PDK1,TCP11L2,SLC37A1,KDM5B,GALNT6,WLS,BACE1,SPATA6,TNFAIP8L2,GAS6,NPC2,SKI,SIPA1L2,PRKCB,RPS11,RASGRF2,TNFRSF1A,ERCC5,RNF130,ST8SIA1,RPL4,AMPD1 |
| 1.965e-02 | -3.93 | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP | 182 | 27 | 17377 | 1707 |
BCL11B,CARD6,ANTXR2,EVL,SLC37A1,FGF13,TNFAIP8L2,BNIP3L,SFXN3,KIF21B,DOCK5,SESN1,PEAK1,SLCO3A1,TXNDC5,RERE,HOPX,SMAD3,TECPR1,SEMA4F,C1orf21,RAP2A,PGM2L1,SGK1,ST8SIA1,RASGRP1,ABCG1 |
| 1.965e-02 | -3.93 | GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN | 182 | 27 | 17377 | 1707 |
TBKBP1,MXI1,SH3BP2,MRC2,PAGE1,FGF13,ZHX3,RHOBTB1,ESRRG,CHRNA6,TJP1,GPSM2,PLCB1,FGFR1,CYP26A1,SMAD3,EPCAM,ABLIM1,IGF1R,SH3GL2,AKT3,TECPR2,BBC3,SPRY2,B4GALT6,CNTN1,LPP |
| 1.965e-02 | -3.93 | GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_16H_ANTI_IGM_STIM_BCELL_UP | 182 | 27 | 17377 | 1707 |
ANKRD13D,ACSL1,PXN,ID1,ITPRIP,BLVRB,APBB1,IPO5,RNF125,BTBD9,FAM117B,KIF21B,USP30,CHST10,MAPKAPK2,FBXO32,IDI1,GYPC,IKZF5,PRKCB,PELI2,OSBPL5,BCL6,TUFT1,PTPRE,RAB30,ATP2B1 |
| 1.967e-02 | -3.93 | regulation of cell projection assembly | biological process | GO:0060491 | 186 | 27 | 17256 | 1658 |
TENM1,FER,SSH3,GPM6A,DNM3,EVL,RHOQ,MYO10,TBC1D1,EPS8,PFN2,TBC1D16,TBC1D30,PPP1R9A,TBC1D2,TBC1D19,RIPOR2,PRKCD,DYNC2LI1,KLF5,PLD1,ATG5,NRP1,FNBP1L,COBL,SLIT2,TBC1D8 |
| 1.967e-02 | -3.93 | EVL (Enah/Vasp-like) | protein interactions | 51466 | 48 | 10 | 17029 | 1718 |
NAP1L5,TRIM9,BAG3,EVL,TES,APBB1,ABI3,ENAH,PFN2,SEMA6A |
| 1.968e-02 | -3.93 | MORI_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_MATURE_B_LYMPHOCYTE_UP | 86 | 15 | 17377 | 1707 |
CXCR5,PTPRC,ID3,MYCBP2,SH3BP2,GPR65,PTPN6,OSBPL5,SELL,CR2,RASA3,CD40,BARX1,LPP,MEF2C |
| 1.968e-02 | -3.93 | GO_RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 86 | 15 | 17377 | 1707 |
PAK1,TNIK,ACVR1,BMPR2,ACVR1C,MAP2K6,SLK,STRADB,ACVR2A,MAPK4,MAPK13,ACVR2B,BMPR1A,MAPK10,STK24 |
| 1.968e-02 | -3.93 | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | MSigDB lists | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | 86 | 15 | 17377 | 1707 |
MICAL2,COL9A3,ENO2,MAGEA3,SLC7A5,SSX1,AHNAK2,EFNA3,PSD3,GPSM2,NCAM1,MAGEA6,SHOX2,FZD1,TRPS1 |
| 1.968e-02 | -3.93 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_DN | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_10HR_DN | 29 | 7 | 17377 | 1707 |
MAFB,INSIG1,FOXG1,DOCK2,MCF2L,STC2,HEY1 |
| 1.968e-02 | -3.93 | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 29 | 7 | 17377 | 1707 |
MN1,DLX2,CD55,PHLDA2,MYC,CTH,TFAP2A |
| 1.968e-02 | -3.93 | MODULE_265 | MSigDB lists | MODULE_265 | 29 | 7 | 17377 | 1707 |
CXCR5,IL13RA1,IL18R1,LEPR,IL1RAP,GHR,F3 |
| 1.968e-02 | -3.93 | VALK_AML_CLUSTER_12 | MSigDB lists | VALK_AML_CLUSTER_12 | 29 | 7 | 17377 | 1707 |
GALNT3,HGF,SKAP2,FGF13,STXBP1,NKX3-2,AFF2 |
| 1.968e-02 | -3.93 | LU_TUMOR_VASCULATURE_UP | MSigDB lists | LU_TUMOR_VASCULATURE_UP | 29 | 7 | 17377 | 1707 |
CHN1,LCP2,PMAIP1,RPS11,CMTM8,HOPX,SCIN |
| 1.968e-02 | -3.93 | GO_REGULATION_OF_SYNAPTIC_VESICLE_TRANSPORT | MSigDB lists | GO_REGULATION_OF_SYNAPTIC_VESICLE_TRANSPORT | 29 | 7 | 17377 | 1707 |
BTBD9,UNC13B,SEPT5,STXBP1,PFN2,LRRK2,SNCA |
| 1.968e-02 | -3.93 | YANAGIHARA_ESX1_TARGETS | MSigDB lists | YANAGIHARA_ESX1_TARGETS | 29 | 7 | 17377 | 1707 |
PRKAA2,MARCKS,DYNC2H1,HMGCS1,RASAL2,PCLO,INPP4B |
| 1.970e-02 | -3.93 | Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol | KEGG pathways | M00101 | 11 | 4 | 7161 | 730 |
CYP51A1,MSMO1,DHCR7,DHCR24 |
| 1.970e-02 | -3.93 | Lysine degradation, lysine => saccharopine => acetoacetyl-CoA | KEGG pathways | hsa_M00032 | 11 | 4 | 7161 | 730 |
EHHADH,AADAT,AASS,OGDHL |
| 1.970e-02 | -3.93 | Lysine degradation, lysine => saccharopine => acetoacetyl-CoA | KEGG pathways | M00032 | 11 | 4 | 7161 | 730 |
EHHADH,AADAT,AASS,OGDHL |
| 1.970e-02 | -3.93 | Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol | KEGG pathways | hsa_M00101 | 11 | 4 | 7161 | 730 |
CYP51A1,MSMO1,DHCR7,DHCR24 |
| 1.976e-02 | -3.92 | negative regulation of cellular protein metabolic process | biological process | GO:0032269 | 1071 | 123 | 17256 | 1658 |
PHACTR3,PRKN,PCSK1N,PPP4R4,DUSP8,RECK,C4A,DNAJC3,NPM1,NDRG2,CEBPA,NTRK3,CHAC1,PIBF1,SKI,RIDA,PPM1E,PPP1R26,ZFYVE28,CNKSR3,DACT1,MAGEA3,DAB2IP,FHIT,PDE4D,PROS1,SERPINH1,TLR4,SLIT2,LAMP3,IGFBP3,CD55,SESN2,ATF4,GAPDH,CSN2,COL4A3,NOP53,PTPN6,LRRK2,PREX1,DEPTOR,AGO4,ATF3,PRKAR2B,SYNJ2BP,C4BPB,SNCA,WARS,CAMK2N1,ENPP1,PTPRJ,BEX3,SH3RF1,NCKAP1L,GBP1,EIF4EBP1,WWTR1,NCOA7,DUSP19,C8orf88,HGF,SERPINI1,INPP5F,SPRY4,ATG5,PPARGC1A,SPOCK3,PRKAA2,LATS2,UBASH3B,IPO5,DHCR24,OPHN1,UBAC2,IGF2BP2,GAS6,TNFRSF10C,PKN1,SPINK5,GAS1,RPL13A,MECOM,DDIT4,FRY,IGF1R,MAP1A,PAIP2B,MYC,FLRT3,PRKCD,C1QL4,RASD2,LRP6,ERRFI1,SMAD6,SPRY2,ZFP36L2,HMGCR,DUSP1,BOD1,CRIM1,DUSP9,PHACTR2,RACK1,HERPUD1,CPEB1,DKK1,BEX4,PTPRC,TRIB3,MYADM,PMEPA1,ACER2,LAPTM4B,BMP4,LRRK1,SMYD3,TESC,ATP2B4,SFN,LARP1,PKIA |
| 1.978e-02 | -3.92 | cytokine production | biological process | GO:0001816 | 136 | 21 | 17256 | 1658 |
CD55,PNP,LILRB1,GATA3,WNT11,GAS6,BATF,LCP2,TLR6,FGFR1,HEG1,MCOLN2,EOMES,ADAMTS3,PRKCD,INAVA,TNFSF4,TLR4,IL1RAP,RASGRP1,PCSK5 |
| 1.978e-02 | -3.92 | LEIN_OLIGODENDROCYTE_MARKERS | MSigDB lists | LEIN_OLIGODENDROCYTE_MARKERS | 71 | 13 | 17377 | 1707 |
GPR37,SERINC5,GSN,UGT8,HMGCS1,CA2,EEF2,MAP2K6,TTYH2,SGK1,SCD,GATM,PLEKHB1 |
| 1.978e-02 | -3.92 | V$LXR_Q3 | MSigDB lists | V$LXR_Q3 | 71 | 13 | 17377 | 1707 |
PCSK1N,RNF145,BLVRB,MAFB,SGK1,RASL11B,IKZF2,SPRY2,HPCAL4,LRP3,GLI1,ABCG1,NKX2-1 |
| 1.978e-02 | -3.92 | LINDVALL_IMMORTALIZED_BY_TERT_UP | MSigDB lists | LINDVALL_IMMORTALIZED_BY_TERT_UP | 71 | 13 | 17377 | 1707 |
EFEMP1,RNF150,SLC22A18,EHD3,STC2,RGS10,ASS1,BMP4,SNX9,ATP2B1,FKBP11,MKX,DKK1 |
| 1.978e-02 | -3.92 | V$AP1_C | MSigDB lists | V$AP1_C | 258 | 36 | 17377 | 1707 |
CXCR5,NUDT10,SV2B,SEC24D,XYLT1,STAT5B,FAM81A,ABHD4,PRR7,PHLDA2,ZFYVE9,TTC1,TUBB4A,MAP1A,SLC22A18,MET,SNX10,PDGFRB,MARK1,USP2,ARAP2,ESRRG,PACSIN3,AIG1,PRDM1,CTTNBP2NL,ATP1B1,ARHGAP32,GABARAPL1,MAP2,PKN3,SLCO5A1,DIRAS1,FRMD5,SFN,LPP |
| 1.979e-02 | -3.92 | positive regulation of calcium ion transmembrane transport | biological process | GO:1904427 | 65 | 12 | 17256 | 1658 |
CXCL10,GSTM2,CACNB2,ANK2,EHD3,TRPC1,RYR2,GSTO1,ATP1B1,HSPA2,CACNA2D1,SNCA |
| 1.980e-02 | -3.92 | Voltage gated Potassium channels | REACTOME pathways | R-HSA-1296072 | 44 | 9 | 10287 | 971 |
KCNV1,KCNAB1,KCNQ3,KCNH5,KCNG1,KCNS3,KCND3,KCNC4,KCNB2 |
| 1.980e-02 | -3.92 | Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism | REACTOME pathways | R-HSA-6788656 | 44 | 9 | 10287 | 971 |
PHYKPL,SLC3A2,HYKK,AADAT,AASS,TDO2,KMO,AMDHD1,SLC7A5 |
| 1.987e-02 | -3.92 | IFT57 (intraflagellar transport 57) | protein interactions | 55081 | 55 | 11 | 17029 | 1718 |
TRPM4,TMCO3,IFT81,LCA5,BNIP1,ATP9A,HOMER2,TTC30A,HIP1,TTC30B,HOMER3 |
| 1.987e-02 | -3.92 | FSD1 (fibronectin type III and SPRY domain containing 1) | protein interactions | 79187 | 55 | 11 | 17029 | 1718 |
FSD1,PAK1,DDAH1,HMGCS1,TES,BLVRB,EEPD1,PLS1,NCS1,CTH,SNCA |
| 1.987e-02 | -3.92 | PFN2 (profilin 2) | protein interactions | 5217 | 55 | 11 | 17029 | 1718 |
GSN,EVL,HMGCS1,BLVRB,NDUFB8,PTPRS,ACTA2,ENAH,PALLD,SEPT5,PFN2 |
| 1.993e-02 | -3.92 | muscle tissue development | biological process | GO:0060537 | 299 | 40 | 17256 | 1658 |
ACVR1,BMPR2,BVES,PKP2,DNER,MYORG,FHOD3,SKI,FOXP2,TGFBR3,EEF2,KCNAB1,EOMES,DSG2,COL19A1,MYH15,PDGFRB,MYLK3,FHL2,RYR2,ATF3,CBY1,ZFPM2,DSP,GJC1,HEG1,MSC,HLF,RIPOR2,POPDC3,HEYL,SVIL,SEMA3C,KLF5,MYOM2,BMPR1A,BMP4,ATG5,TPM1,MEF2C |
| 1.995e-02 | -3.91 | Arf6 signaling events | Pathway Interaction DB | arf6_pathway | 34 | 9 | 2226 | 278 |
PXN,ARAP2,CYTH3,ITGB3,HGF,GULP1,IPCEF1,MET,TSHR |
| 1.995e-02 | -3.91 | transcription regulatory region DNA binding | molecular function | GO:0044212 | 877 | 104 | 17224 | 1680 |
CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,NPM1,STAT5B,BCL6B,CEBPA,IKZF2,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,WNT11,ATOH1,BATF,SNCA,BCL11A,BATF3,SMAD3,MSC,ZNF93,TCF7L1,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,GFI1,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3,FOXA1 |
| 1.999e-02 | -3.91 | morphogenesis of a branching epithelium | biological process | GO:0061138 | 161 | 24 | 17256 | 1658 |
PAK1,ACVR1,CELSR1,KDM5B,ST14,DCHS1,YAP1,DDR1,FGFR1,FAT4,MYC,CSF1,LRP6,SEMA3C,HOXD13,BMP4,MET,NRP1,SEMA3A,SPRY2,SLIT2,FOXA1,BTRC,NKX2-1 |
| 2.000e-02 | -3.91 | GSE2706_UNSTIM_VS_8H_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_R848_DC_UP | 174 | 26 | 17377 | 1707 |
MAN2B2,NMNAT3,AVPI1,UROS,EBPL,ZCCHC24,BLVRB,XYLT1,NFIA,ABAT,CREB5,TRPS1,CPVL,SLC22A18,WFS1,P4HA2,GAS2L3,KIAA0513,CLMN,TMEM117,PIK3C2B,PLD1,DBP,ZFP36L2,FES,CYP1B1 |
| 2.000e-02 | -3.91 | GO_CELL_ADHESION_MOLECULE_BINDING | MSigDB lists | GO_CELL_ADHESION_MOLECULE_BINDING | 174 | 26 | 17377 | 1707 |
ITGB7,PXN,FN1,COL4A3,PTPRD,AKAP5,WISP3,ITGA6,SELL,NLGN4X,CADM2,NRXN1,DSP,JAM3,CTNNA2,FGFR1,TBC1D2,EPCAM,FBN1,THBS4,DSG2,ITGA2,ITGB3,CDH17,CPE,SYK |
| 2.003e-02 | -3.91 | dendritic spine | cellular component | GO:0043197 | 155 | 23 | 18223 | 1724 |
GPM6A,DNM3,FARP1,SHANK2,APBB1,OPHN1,PRKAR2B,ARHGAP32,CANX,APBA1,PPP1R9A,NEDD4,BAIAP2,ARHGAP44,MAP1B,KCNN2,MPP2,RGS10,CTTN,CTTNBP2,APBA2,LZTS1,ATP2B1 |
| 2.005e-02 | -3.91 | kidney epithelium development | biological process | GO:0072073 | 128 | 20 | 17256 | 1658 |
ROBO2,SMAD9,LGR4,KLHL3,DCHS1,GATA3,WNT11,FGFR1,SMAD3,EPCAM,FAT4,MYC,HEYL,BMP4,SMAD6,MAGI2,SLIT2,SIX2,POU3F3,MEF2C |
| 2.011e-02 | -3.91 | MARTINEZ_RB1_AND_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_DN | 550 | 69 | 17377 | 1707 |
TRIM2,PRSS12,ST14,RBFOX2,DNAJC3,VAMP8,FHDC1,PLXNA2,PKP2,COL18A1,CHAC1,CANX,DDR1,AARS,IDI1,GRHL1,MARCKS,PJA1,PTPRE,MEIS2,COL6A2,GJB2,PANK1,ATF7IP2,NFIA,ACVR2B,ZDHHC14,SNCA,SLC39A14,BACH2,SH3RF1,EIF4EBP1,TMOD2,UNC5B,TC2N,CRYL1,COL9A3,ESRP1,RASL11B,GTF2IRD1,SFXN3,PFN2,TNFRSF19,GAS1,HOPX,NEO1,HMGCS1,AFF2,BHLHA15,CERS4,ERRFI1,SLC45A3,RPL26,KDM5B,MYO10,CRIM1,PTPN13,HOMER2,ELOVL3,RPL21,EFNA3,WWC1,SHISA2,ATP11A,PLCB1,CEBPB,PMEPA1,PLOD2,SLC7A5 |
| 2.012e-02 | -3.91 | - | gene3d domains | 1.10.555.10 | 66 | 13 | 8148 | 867 |
CHN1,ARHGAP26,ARHGAP21,CHN2,ARAP2,ARHGAP22,SRGAP1,OPHN1,ARHGAP28,ARHGAP32,FAM13A,ARHGAP44,SYDE2 |
| 2.014e-02 | -3.91 | catalytic activity, acting on a glycoprotein | molecular function | GO:0140103 | 23 | 6 | 17224 | 1680 |
CCDC126,MGAT5B,B4GALNT3,MGAT1,B4GALT7,MGAT4B |
| 2.014e-02 | -3.91 | transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding | molecular function | GO:0000983 | 23 | 6 | 17224 | 1680 |
SMAD3,TAF4B,DACH2,HEYL,MEF2C,HEY1 |
| 2.014e-02 | -3.91 | calcium-release channel activity | molecular function | GO:0015278 | 23 | 6 | 17224 | 1680 |
RYR2,RASA3,MCOLN2,ITPR2,JPH1,MCOLN3 |
| 2.014e-02 | -3.90 | GO_SULFUR_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_SULFUR_COMPOUND_METABOLIC_PROCESS | 345 | 46 | 17377 | 1707 |
UST,MVK,ACSL1,AASS,ELOVL7,XYLT1,CBS,STAT5B,SCD,CHSY1,CHAC1,BCAN,PHGDH,SLC19A2,AADAT,GHR,HS3ST5,GSTM3,FAR2,ESD,CTH,B4GALT6,CHSY3,VNN2,MICAL2,OPLAH,GDAP1,GSTM2,GSTM4,MVD,MGST3,ELOVL3,FASN,GSTO1,TPK1,GLCE,ENPP1,HPSE,GSTO2,TDO2,PEMT,DSEL,HS3ST3B1,SPOCK3,OCLN,HS6ST3 |
| 2.016e-02 | -3.90 | alpha-amino acid metabolic process | biological process | GO:1901605 | 212 | 30 | 17256 | 1658 |
GPT2,NMNAT3,SERINC5,HYKK,AASS,GCAT,ASS1,CBS,STAT5B,SLC1A3,PHGDH,ADSSL1,AMDHD1,PYCR1,DDAH1,ASNS,AADAT,PLOD2,TDO2,ERO1B,KMO,PEMT,GHR,P4HA1,PHYKPL,GATM,PSPH,NOS3,GLDC,CTH |
| 2.021e-02 | -3.90 | O-linked glycosylation | REACTOME pathways | R-HSA-5173105 | 114 | 18 | 10287 | 971 |
B3GLCT,THSD4,GALNT6,GALNT12,ST6GAL1,GALNT17,GALNT13,ADAMTS6,ST6GALNAC3,GALNT14,ADAMTS17,GALNT3,GALNT1,ADAMTS3,THSD7B,THSD1,GALNT18,B4GALT6 |
| 2.022e-02 | -3.90 | PE/DAG-bd | interpro domains | IPR002219 | 64 | 12 | 18492 | 1811 |
CHN1,VAV3,CHN2,ARHGEF28,PDZD8,UNC13B,PRKCB,PRKCD,PRKCQ,CDC42BPA,PRKCA,RASGRP1 |
| 2.024e-02 | -3.90 | gland morphogenesis | biological process | GO:0022612 | 96 | 16 | 17256 | 1658 |
CEBPB,NRG3,EDA,KDM5B,CSF1,PLAG1,LRP6,SEMA3C,HOXD13,BMP4,NRP1,DDR1,SEMA3A,FOXA1,FGFR1,BTRC |
| 2.031e-02 | -3.90 | MODULE_169 | MSigDB lists | MODULE_169 | 94 | 16 | 17377 | 1707 |
MICAL2,RGS16,BCL7A,USP2,IL32,CLGN,CRIP2,BIK,TNFAIP8L2,BCL6,CR2,PRKAR2B,TOX,SCD,DENND3,MME |
| 2.033e-02 | -3.90 | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_UP | 166 | 25 | 17377 | 1707 |
MAN2B2,ITPRIP,ARHGEF11,UBASH3B,RAPGEF2,AGPAT4,EFHC2,TCEA3,RNF125,PRKCA,MBNL2,TTC28,DDIT4,IRS2,BAG3,PELI2,TSC22D1,ZBTB20,FHIT,PDE4D,SUSD4,SMYD3,LPP,PCSK5,DUSP1 |
| 2.033e-02 | -3.90 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_DN | 166 | 25 | 17377 | 1707 |
DYRK3,SLC27A2,OTOGL,RAPGEF2,TNFSF13B,HERC5,SLC25A28,ADAMTS6,ATF3,DOCK3,PGAP1,WARS,ISG20,SLC35F1,MCOLN2,GBP1,ITGB3,KCNMB3,ZDHHC23,TSC22D1,ALPK1,SP140,MED12L,LAMP3,PARP9 |
| 2.033e-02 | -3.90 | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN | MSigDB lists | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN | 166 | 25 | 17377 | 1707 |
CREB3L2,UST,UROS,DNAJC3,TMEM126A,STRADB,PRKAR2B,COTL1,MFSD6,KBTBD11,NAALADL2,NAP1L5,SFXN1,TMEM237,PIK3AP1,KMO,SLC22A18,MATN2,TRIM3,LAPTM4B,NAP1L3,HS3ST3B1,FNBP1L,IL1RAP,PARP9 |
| 2.045e-02 | -3.89 | cofactor metabolic process | biological process | GO:0051186 | 489 | 61 | 17256 | 1658 |
GPT2,NMNAT3,MOCOS,MVK,ACSL1,ENO2,AASS,BLVRB,ELOVL7,STAT5B,SCD,CHAC1,NUDT12,QPRT,HMGCS1,AADAT,KMO,ALDOC,ALDH1L1,GHR,PRKG2,GSTM3,MDH1B,FAR2,PCK2,ENO1,PARP9,NOS3,HMGCR,OPLAH,VNN2,GDAP1,ATP5IF1,GAPDH,GSTM2,PNP,UROS,PFKFB2,ALDH1L2,GSTM4,MVD,PANK1,ELOVL3,HACD1,FASN,NFE2L1,OGDHL,GSTO1,TPK1,GSTO2,TDO2,PEMT,ALDOA,BDH2,HK2,PGM2L1,HK1,PTGES,PANK3,ACSM3,NUDT17 |
| 2.048e-02 | -3.89 | Airflow obstruction(PMID:22837378) | GWAS genes | Airflow obstruction(PMID:22837378) | 18 | 7 | 2388 | 399 |
CREB5,HYKK,CHRNA5,PTPRD,ADGRG6,THSD4,SPATA13 |
| 2.053e-02 | -3.89 | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | 191 | 28 | 17377 | 1707 |
CREB3L2,TRPM4,MGST3,MCTP2,EDEM3,SPATA13,VIM,GPSM2,TGDS,FNDC3A,EXOG,PFN2,TBC1D19,PLOD2,TACC2,SH3RF1,CDC14B,ALDOA,ABI3,TNFRSF1A,P4HA1,SGK1,RNF130,GEM,RCAN3,GATM,RBMS2,GAB2 |
| 2.053e-02 | -3.89 | GSE42724_NAIVE_VS_B1_BCELL_UP | MSigDB lists | GSE42724_NAIVE_VS_B1_BCELL_UP | 191 | 28 | 17377 | 1707 |
ARHGAP26,FRMPD3,PNP,ITPRIP,KLHL13,REL,UBASH3B,RAPGEF2,HSPA12B,WARS,MAPKAPK2,SLC39A14,TMCO3,SETDB2,KPNA3,PLOD2,SH3BP4,HK2,NAP1L3,FBRSL1,SH3BGRL2,SLC22A15,HK1,POU2F2,TMEFF2,LARP1,PARP9,BOD1 |
| 2.053e-02 | -3.89 | GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | MSigDB lists | GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | 191 | 28 | 17377 | 1707 |
GNG12,DNM3,DYRK3,SKAP2,ITGA6,LDLR,PLS1,RASD1,FAM117B,ATF3,LCP2,BBS9,ASPH,HERPUD1,FKBP11,CYP51A1,ATXN7L1,HMGCS1,MYADM,INSIG1,PIK3AP1,EIF4EBP1,FAM107B,PACSIN1,TMEM120B,KCTD1,RAB30,DDIT3 |
| 2.053e-02 | -3.89 | GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN | 191 | 28 | 17377 | 1707 |
IL17RD,LPAR2,RUNX2,SCAMP1,PRSS12,SYT12,MYO1B,SPATA13,ATF3,CTTNBP2NL,PALLD,FRK,CLN5,DOK5,F3,DHX32,RPS6KA2,KCNMB4,ZNF354A,CHRNA5,RND3,GATA2,SRGAP1,PPP2R2B,ERRFI1,NIPAL2,HOXB9,TBC1D8 |
| 2.053e-02 | -3.89 | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP | MSigDB lists | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP | 191 | 28 | 17377 | 1707 |
RGS16,FARP1,TTC39B,SLK,WLS,PTPN13,APBB1,PANK1,YPEL2,GTF2IRD1,MSRB3,KIF5C,ADAMTS6,STAT5B,VIM,C3orf70,SAV1,PRKCA,IKZF2,SNX9,PEAK1,COL27A1,HOPX,ZNF827,GRHL1,MATN2,INPP5F,RNF157 |
| 2.053e-02 | -3.89 | GO_MAGNESIUM_ION_BINDING | MSigDB lists | GO_MAGNESIUM_ION_BINDING | 191 | 28 | 17377 | 1707 |
DYRK3,MARK1,ENO2,CLYBL,ATP9A,ATP8A1,NUAK2,LHPP,CDC42BPA,ATP11A,ADSSL1,INPP1,ATP10D,NCS1,SNCA,GNAI1,ADPRHL1,RPS6KA2,IDI1,PRTFDC1,ERN1,GEM,MAST4,ENO1,TESC,PSPH,PRKACB,MAST1 |
| 2.053e-02 | -3.89 | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN | MSigDB lists | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN | 191 | 28 | 17377 | 1707 |
ARHGAP26,GARS,LGALS3,SIDT1,ST14,RECK,PTPN13,STAT4,FHL2,KIF5C,VIM,CHSY1,DOCK5,IL18R1,TRPS1,HOPX,SMAD3,GALNT3,MCOLN2,ENTPD1,BAG3,SEMA4F,GPR155,ERN1,PCGF2,TMEM37,ERRFI1,RNF157 |
| 2.053e-02 | -3.89 | regulatory region nucleic acid binding | molecular function | GO:0001067 | 878 | 104 | 17224 | 1680 |
CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,NPM1,STAT5B,BCL6B,CEBPA,IKZF2,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,WNT11,ATOH1,BATF,SNCA,BCL11A,BATF3,SMAD3,MSC,ZNF93,TCF7L1,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,GFI1,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3,FOXA1 |
| 2.058e-02 | -3.88 | FARMER_BREAST_CANCER_CLUSTER_7 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_7 | 17 | 5 | 17377 | 1707 |
SCD,BLVRB,GHR,SREBF1,FASN |
| 2.058e-02 | -3.88 | GO_NOTOCHORD_DEVELOPMENT | MSigDB lists | GO_NOTOCHORD_DEVELOPMENT | 17 | 5 | 17377 | 1707 |
YAP1,ID3,WNT11,COBL,GLI1 |
| 2.058e-02 | -3.88 | KOBAYASHI_RESPONSE_TO_ROMIDEPSIN | MSigDB lists | KOBAYASHI_RESPONSE_TO_ROMIDEPSIN | 17 | 5 | 17377 | 1707 |
EFNB2,ELOVL4,ARL4D,DENND3,FABP6 |
| 2.058e-02 | -3.88 | GO_NEGATIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION | 17 | 5 | 17377 | 1707 |
EFEMP1,CHADL,BMP4,NKX3-2,SNAI2 |
| 2.058e-02 | -3.88 | GO_POSITIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION | 17 | 5 | 17377 | 1707 |
BBC3,HRK,PMAIP1,SNX9,BIK |
| 2.058e-02 | -3.88 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 17 | 5 | 17377 | 1707 |
GPR37,HGF,MET,LRRK2,PYCR1 |
| 2.058e-02 | -3.88 | GO_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION | 17 | 5 | 17377 | 1707 |
ABAT,UBASH3B,PRKCD,NOS3,PRKG1 |
| 2.058e-02 | -3.88 | GO_SODIUM_CHANNEL_COMPLEX | MSigDB lists | GO_SODIUM_CHANNEL_COMPLEX | 17 | 5 | 17377 | 1707 |
SCN5A,SCN2A,SCN1B,SCN8A,SCN3A |
| 2.058e-02 | -3.88 | KYNG_WERNER_SYNDROM_UP | MSigDB lists | KYNG_WERNER_SYNDROM_UP | 17 | 5 | 17377 | 1707 |
MBNL2,RHOD,C15orf41,ITGA2,IGFBP3 |
| 2.058e-02 | -3.88 | GO_REGULATION_OF_HYDROGEN_PEROXIDE_INDUCED_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_HYDROGEN_PEROXIDE_INDUCED_CELL_DEATH | 17 | 5 | 17377 | 1707 |
GPR37,HGF,MET,LRRK2,PYCR1 |
| 2.058e-02 | -3.88 | GO_REGULATION_OF_COLLATERAL_SPROUTING | MSigDB lists | GO_REGULATION_OF_COLLATERAL_SPROUTING | 17 | 5 | 17377 | 1707 |
RND2,BDNF,FGF13,DCC,BCL11A |
| 2.058e-02 | -3.88 | KIM_PTEN_TARGETS_UP | MSigDB lists | KIM_PTEN_TARGETS_UP | 17 | 5 | 17377 | 1707 |
GPM6A,PLD1,SKAP2,SLC7A11,FAM162A |
| 2.058e-02 | -3.88 | MAPK1 (mitogen-activated protein kinase 1) | protein interactions | 5594 | 311 | 43 | 17029 | 1718 |
PLA2G4A,PRKN,DUSP8,ENAH,SORBS3,STAT5B,NTRK3,CUEDC2,NAV1,RPS6KA2,GATA2,RPS11,MYC,PRKCD,SREBF1,BCL6,PDE4D,YBX3,PTPRE,NEB,GAB2,DUSP1,NKX2-1,PAK1,PXN,GAPDH,DCC,NR4A1,FHL2,DUSP9,FERMT2,PLCB1,SNCA,CEBPB,SMAD3,MAPKAPK2,DYRK1B,MAP2K6,EIF4EBP1,TNFRSF1A,DUSP19,GRB10,LIFR |
| 2.062e-02 | -3.88 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_UP | 158 | 24 | 17377 | 1707 |
BCL11B,VEGFC,EIF4E3,TES,LRMP,DEPTOR,FHDC1,TTYH2,CTTNBP2NL,F12,SEL1L3,FOXG1,BCL11A,IRS2,CXCL10,TMEM154,MARVELD2,PLK2,ITGA2,KCNMB3,TSC22D1,GEM,VASH2,CTNND2 |
| 2.062e-02 | -3.88 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_C_UP | 158 | 24 | 17377 | 1707 |
RPS20,B3GALT1,PTPRD,DNAJC3,FOXN3,UGDH,GPSM1,COTL1,SLC12A6,LACC1,FNDC3A,TNFRSF19,COL27A1,TPK1,SPEG,CXCL10,DDAH1,ZBTB38,FAT4,UNC13B,KLF12,FAM149A,SH3BGRL2,FKBP14 |
| 2.062e-02 | -3.88 | GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS | 158 | 24 | 17377 | 1707 |
PLSCR4,FN1,VLDLR,LITAF,LILRB1,ASS1,CD40,TLR6,CPEB1,CEBPB,CXCL10,WFS1,XBP1,DAB2IP,PDE4D,CMPK2,TNFSF4,PPARGC1A,GFI1,TLR4,SYK,DDIT3,NOS3,MEF2C |
| 2.062e-02 | -3.88 | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_HET_DN | MSigDB lists | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_HET_DN | 158 | 24 | 17377 | 1707 |
EFNB2,PRKAA2,FGF13,CLGN,ESRRG,ELOVL7,CAPN5,FERMT2,ILDR2,STEAP1,NEDD4,C11orf45,GJC1,TEX15,ZBTB38,KCNAB1,GRHL1,FBN1,KAZN,ZNF214,XBP1,MCC,MARCH3,NEK11 |
| 2.062e-02 | -3.88 | Coro1c (coronin, actin binding protein 1C) | protein interactions | 23790 | 146 | 23 | 17029 | 1718 |
DBN1,PHLDB2,FARP1,AMOTL1,DSTN,MYO1B,BEGAIN,PACSIN3,PPP1R9A,GSN,ABLIM1,ARHGAP21,TMEM237,DSG2,RAI14,SVIL,PLD1,CTTN,TPM1,RRAS2,FMNL2,COBL,HACE1 |
| 2.065e-02 | -3.88 | CAAGGAT,MIR-362 | MSigDB lists | CAAGGAT,MIR-362 | 64 | 12 | 17377 | 1707 |
CNTN4,SEMA4F,RNF145,LGALS3,TRIM3,PSD3,ACVR2A,GPR180,RNF24,CHSY1,PRKCA,BCL11A |
| 2.065e-02 | -3.88 | C2_dom | interpro domains | IPR000008 | 126 | 20 | 18492 | 1811 |
PLA2G4A,DOC2A,RASAL2,SYT12,CAPN5,MCTP2,HECW2,RASA3,PRKCA,SYT14,PLCB1,PCLO,RAB11FIP5,CPNE2,UNC13B,PRKCB,PIK3C2B,DAB2IP,TC2N,RIMS2 |
| 2.070e-02 | -3.88 | positive regulation of apoptotic process | biological process | GO:0043065 | 628 | 76 | 17256 | 1658 |
GRIK2,COL18A1,LILRB1,NTRK3,TIAM2,F3,SCIN,GSDME,TLR3,RPS6KA2,UNC13B,PMAIP1,BCL6,DAB2IP,HRK,FANK1,SLIT2,PDGFRB,IGFBP3,CYP1B1,ATF4,GAPDH,COL4A3,ACVR1C,BNIP3L,PREX1,ATF3,WNT11,CD40,SAV1,ARHGEF26,SNCA,SMAD3,GSN,BEX3,RASGRF2,HPGD,BBC3,TNFSF15,PPARGC1A,MEF2C,LATS2,ARHGEF11,ITGA6,APBB1,BIK,TPD52L1,MCF2L,MYC,PRKCD,PRELID1,TFAP2A,BNIP3,PNMA2,DUSP1,HMGCR,RPL26,VAV3,ATP5IF1,UNC5C,MSX1,RAPGEF2,HIP1,OBSCN,RACK1,FAM162A,GPLD1,ID3,NACC2,ACER2,MAP2K6,BMP4,MAP3K20,SFN,FOXA1,DDIT3 |
| 2.070e-02 | -3.88 | FORTSCHEGGER_PHF8_TARGETS_DN | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_DN | 715 | 87 | 17377 | 1707 |
CGN,FGF13,VAMP8,LMCD1,CANX,PRKCA,FKBP11,SPEG,TGFBR3,TACC2,SLC22A18,RAP2A,SCRN1,GULP1,PPP2R2B,TLR4,SSH3,TNK2,FER,PHLDB2,GCA,ERGIC1,THSD4,CYB5R2,C3orf52,NFIA,EFHC1,ROR1,EML1,TPK1,ISG20,CAMK2N1,GNB4,AHNAK2,MAOA,IGFBP6,FN1,ENO2,ZHX3,CHCHD7,ST6GAL1,STXBP6,ELOVL7,OPHN1,SETBP1,SCD,CHSY1,SFXN3,NDFIP2,GDPD5,NEDD4,FSD1,HMGCS1,TECPR1,DYNC2H1,LRP12,PFKFB4,DPYSL5,MICAL2,PXN,GSTM4,AGPAT4,MPP1,GPSM1,PRRG1,MAFB,OBSCN,PLS1,ATP11A,CLN5,BAIAP2,HEG1,DKK1,NAP1L5,FCHO2,FBN1,MATN2,RAB31,TUFT1,SQLE,SLC22A15,HK1,PTGES,KIF1B,SMYD3,SFN,BTRC |
| 2.076e-02 | -3.87 | GO_RESPONSE_TO_RETINOIC_ACID | MSigDB lists | GO_RESPONSE_TO_RETINOIC_ACID | 102 | 17 | 17377 | 1707 |
EPHA3,GDAP1,TRIM16,FZD4,YAP1,WNT11,NTRK3,BMP6,DKK1,ACER2,PTK7,SREBF1,BMP4,PTGES,TESC,PDGFRB,DUSP1 |
| 2.076e-02 | -3.87 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP | 102 | 17 | 17377 | 1707 |
SYNPO2,TRIM2,GSTM4,FAM102B,PRKAR2B,PLCB1,ARHGEF26,BCL11A,MECOM,TIFA,MAP2K6,ZNF704,PTPRS,SUSD4,GATM,FOXA1,HEY1 |
| 2.079e-02 | -3.87 | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | MSigDB lists | MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | 23 | 6 | 17377 | 1707 |
RAB3B,FGR,SESN2,COL6A2,GEM,PDGFRB |
| 2.079e-02 | -3.87 | GO_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT | 23 | 6 | 17377 | 1707 |
EFEMP1,CHADL,WNT11,BMP4,NKX3-2,SNAI2 |
| 2.079e-02 | -3.87 | GO_REGULATION_OF_METANEPHROS_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_METANEPHROS_DEVELOPMENT | 23 | 6 | 17377 | 1707 |
YAP1,BMP4,FAT4,MYC,WWTR1,PDGFRB |
| 2.079e-02 | -3.87 | GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_CALCIUM_ION_SIGNALING | MSigDB lists | GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_CALCIUM_ION_SIGNALING | 23 | 6 | 17377 | 1707 |
RYR2,GSTO1,GSTM2,ATP1B1,ASPH,ANK2 |
| 2.079e-02 | -3.87 | GO_HISTONE_PHOSPHORYLATION | MSigDB lists | GO_HISTONE_PHOSPHORYLATION | 23 | 6 | 17377 | 1707 |
PRKAA2,NEK11,PKN1,PRKCA,PRKCB,PRKCD |
| 2.079e-02 | -3.87 | GO_NEGATIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MYOBLAST_DIFFERENTIATION | 23 | 6 | 17377 | 1707 |
PRICKLE1,ID3,CXCL10,BMP4,MSTN,DDIT3 |
| 2.079e-02 | -3.87 | LA_MEN1_TARGETS | MSigDB lists | LA_MEN1_TARGETS | 23 | 6 | 17377 | 1707 |
BCL6B,RGS16,SORBS1,FGF13,SNX10,F3 |
| 2.079e-02 | -3.87 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | MSigDB lists | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | 23 | 6 | 17377 | 1707 |
DAGLA,PRKCQ,ITPR2,TRPC3,RASGRP1,PRKCD |
| 2.084e-02 | -3.87 | protein kinase A binding | molecular function | GO:0051018 | 50 | 10 | 17224 | 1680 |
C2orf88,AKAP7,AKAP5,DACT1,LRRK2,RYR2,PRKAR2B,MYRIP,CRYBG3,PKIA |
| 2.086e-02 | -3.87 | MARTINEZ_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_TP53_TARGETS_DN | 551 | 69 | 17377 | 1707 |
TRIM2,PRSS12,ST14,RBFOX2,DNAJC3,VAMP8,FHDC1,PLXNA2,PKP2,COL18A1,CHAC1,CANX,DDR1,AARS,IDI1,GRHL1,MARCKS,PTPRE,MEIS2,COL6A2,GJB2,PANK1,ATF7IP2,NFIA,ACVR2B,ZDHHC14,SNCA,SLC39A14,BACH2,SH3RF1,EIF4EBP1,TMOD2,UNC5B,TC2N,CRYL1,COL9A3,ESRP1,RASL11B,GTF2IRD1,SFXN3,PFN2,GAS1,HOPX,NEO1,HMGCS1,AFF2,BHLHA15,CERS4,ERRFI1,RPL26,KDM5B,MYO10,HNF4G,CRIM1,PTPN13,HOMER2,ELOVL3,RPL21,EFNA3,FHL2,WWC1,SHISA2,ATP11A,PLCB1,CEBPB,PMEPA1,PLOD2,SLC7A5,SLC1A5 |
| 2.086e-02 | -3.87 | GRIN2D (glutamate ionotropic receptor NMDA type subunit 2D) | protein interactions | 2906 | 35 | 8 | 17029 | 1718 |
TJP1,DLG2,CDH2,PRKCB,MAP2,RAP2A,NEDD4,PATJ |
| 2.086e-02 | -3.87 | DCN (decorin) | protein interactions | 1634 | 35 | 8 | 17029 | 1718 |
COL4A5,CHSY1,COL4A3,MET,FN1,COL14A1,FBN1,COL4A4 |
| 2.086e-02 | -3.87 | BNIP3L (BCL2 interacting protein 3 like) | protein interactions | 665 | 35 | 8 | 17029 | 1718 |
ROBO2,KLHL23,BNIP3L,STEAP3,BNIP3,SMCO4,DOK5,GABARAPL1 |
| 2.086e-02 | -3.87 | NOS1 (nitric oxide synthase 1) | protein interactions | 4842 | 35 | 8 | 17029 | 1718 |
PTPN6,ZDHHC23,ADRB1,DLG2,RASD1,PRKCA,NOS1AP,ATP2B4 |
| 2.087e-02 | -3.87 | regulation of chemotaxis | biological process | GO:0050920 | 204 | 29 | 17256 | 1658 |
EFNB2,VEGFC,NBL1,ZSWIM5,BMPR2,ROBO2,MPP1,PLXNA2,NTRK3,GAS6,RARRES2,JAM3,FGFR1,F3,MTUS1,SMAD3,CXCL10,RIPOR2,SEMA4F,NCKAP1L,THBS4,CSF1,ITGA2,SEMA3C,MET,NRP1,SEMA3A,SLIT2,PDGFRB |
| 2.087e-02 | -3.87 | GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_PROLIFERATION | 150 | 23 | 17377 | 1707 |
VEGFC,SCN5A,ID1,KDM5B,BMPR2,NR4A1,TGFA,PRKCA,BMP6,F3,FOXP2,DLX6,MYC,THBS4,XBP1,LAMB1,ITGB3,EGFL7,BMPR1A,BMP4,IQGAP3,VASH2,NRP1 |
| 2.087e-02 | -3.87 | ATF4 (activating transcription factor 4) | protein interactions | 468 | 77 | 14 | 17029 | 1718 |
CEBPB,TRIB3,DISC1,ATF4,GTF2F2,NFE2L1,MAFB,ATF3,CEBPA,BATF,DDIT3,BTRC,CKAP4,BATF3 |
| 2.088e-02 | -3.87 | P_typ_ATPase | interpro domains | IPR001757 | 36 | 8 | 18492 | 1811 |
ATP9A,ATP7B,ATP8A1,ATP11A,ATP10D,ATP2B4,ATP2B1,ATP1A3 |
| 2.088e-02 | -3.87 | RGS | interpro domains | IPR016137 | 36 | 8 | 18492 | 1811 |
RGS17,RGS16,GRK6,RGS7,ARHGEF11,GRK3,RGS10,RGS20 |
| 2.088e-02 | -3.87 | ATPase_P-typ_cyto_dom_N | interpro domains | IPR023299 | 36 | 8 | 18492 | 1811 |
ATP11A,ATP9A,ATP10D,ATP8A1,ATP7B,ATP2B1,ATP2B4,ATP1A3 |
| 2.088e-02 | -3.87 | ATPase_P-typ_transduc_dom_A_sf | interpro domains | IPR008250 | 36 | 8 | 18492 | 1811 |
ATP11A,ATP9A,ATP10D,ATP8A1,ATP7B,ATP2B1,ATP2B4,ATP1A3 |
| 2.088e-02 | -3.87 | ATPase_P-typ_P_site | interpro domains | IPR018303 | 36 | 8 | 18492 | 1811 |
ATP11A,ATP9A,ATP10D,ATP8A1,ATP7B,ATP2B1,ATP2B4,ATP1A3 |
| 2.089e-02 | -3.87 | THUM_SYSTOLIC_HEART_FAILURE_UP | MSigDB lists | THUM_SYSTOLIC_HEART_FAILURE_UP | 381 | 50 | 17377 | 1707 |
EPHA3,PLA2G4A,PLSCR4,ALOX5AP,ST6GAL1,VAMP8,TNFAIP8L2,MSR1,LILRB1,PKP2,RASL11B,NTRK3,FAM198B,DOCK2,SPIRE1,CD53,FBXO32,ZNF438,CNKSR3,PPFIBP1,C1orf53,EIF1,TSPAN12,TLR4,ENO1,ETV1,ZFP36L2,IGFBP3,PDLIM7,PDK1,NECAB1,SKAP2,TMEM43,LRMP,NFIA,CALCRL,RNF125,SDC3,PRDM1,MBNL2,LEPR,JAM3,MAPKAPK2,PTPRC,ENTPD1,DDAH1,GSN,ITGBL1,PLK2,FRMD5 |
| 2.092e-02 | -3.87 | cell projection assembly | biological process | GO:0030031 | 453 | 57 | 17256 | 1658 |
WASF3,TNIK,DNM3,INPPL1,TCTN2,CELSR3,RHOD,ITGA6,OPHN1,PIBF1,BBS9,RAC3,TTC30B,TUBB4A,ABLIM1,LRRC6,CDC14B,DNAH6,RAP2A,EHD3,TBC1D32,CTTN,DYNC2H1,SEPT3,DNAH5,SNX10,B9D1,INTU,VAV3,DISC1,RHOQ,TMEM67,TUBA1A,ABCC4,SPATA6,RAPGEF2,SPATA13,TTC30A,CBY1,PRKAR2B,ARHGEF26,ARMC4,GSN,IFT81,TMEM237,NCKAP1L,WDR19,WWTR1,DYNC2LI1,KLF5,JHY,SEPT5,DNHD1,NRP1,FNBP1L,NPHP1,SHTN1 |
| 2.093e-02 | -3.87 | Sushi/SCR/CCP_sf | interpro domains | IPR035976 | 57 | 11 | 18492 | 1811 |
SUSD3,CD55,CFH,CFHR1,SELL,CR2,C1R,BCAN,SEZ6L2,SUSD4,C4BPB |
| 2.096e-02 | -3.87 | GSE3982_CTRL_VS_LPS_48H_DC_UP | MSigDB lists | GSE3982_CTRL_VS_LPS_48H_DC_UP | 183 | 27 | 17377 | 1707 |
RWDD2A,NDUFA4L2,CHCHD7,ATP9A,THSD4,VLDLR,FHL2,RNF125,SYNJ2BP,RAB38,UCHL3,RNF44,SCIN,TBC1D2,CHN2,KCTD15,TGFBR3,EEF2,NACC2,QPCTL,OPN3,IPCEF1,FAR2,ESD,CEBPD,RBMS2,MEF2C |
| 2.096e-02 | -3.87 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP | 183 | 27 | 17377 | 1707 |
MXI1,PDK1,ZNF395,GABRB2,XYLT1,ATF7IP2,GATA3,CR2,SLC7A2,PFN2,TBC1D30,RPL34,IRS2,TLR3,PDZD8,MCF2L,CDH17,SGK1,KIAA1614,ZBTB20,IPCEF1,PPARGC1A,PTPRE,NR3C2,ZFP36L2,SLC16A10,DUSP1 |
| 2.096e-02 | -3.87 | GSE7460_TREG_VS_TCONV_ACT_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_UP | 183 | 27 | 17377 | 1707 |
RUNX2,GLIPR1L1,ITGA6,ARHGAP22,FHL2,MSRB3,CHUK,ADAMTS6,ATP11A,IKZF2,TTC30B,SCIN,GPR15,SIPA1L2,IKZF3,MYADM,PLAGL1,PMEPA1,AKAP7,CNKSR3,MYO3B,ZNF474,TOX,PROS1,GEM,FNBP1L,FES |
| 2.096e-02 | -3.87 | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 183 | 27 | 17377 | 1707 |
RGS16,INPPL1,SH3BP2,DYRK3,DUSP8,TBC1D1,NR4A1,NPM3,FAM84A,CBS,CREB5,NIPSNAP3B,ARHGEF26,MAPKAPK2,BAG3,ARHGAP21,MARVELD2,PLK2,BCL6,OPN3,INPP5F,SPRY4,GEM,ARL4D,DENND1C,SPRY2,SNPH |
| 2.096e-02 | -3.87 | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_DN | 183 | 27 | 17377 | 1707 |
MRC2,PXN,B3GALT1,MYLK3,MYO10,DSTN,ZCCHC24,EXOC6B,SATB1,BBS9,ARHGEF26,DCBLD2,RAB11FIP5,LGI2,BAG3,AK1,SH3GL2,CACNB2,FRAS1,PDE10A,TNFRSF1A,BMP1,PAM,NPTXR,ZNF365,LIFR,LRP12 |
| 2.099e-02 | -3.86 | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | 225 | 32 | 17377 | 1707 |
ZHX3,AASS,FOXN3,LRP4,VAMP8,ADCY1,PSD3,PHACTR2,SYNJ2BP,C4orf19,BBS9,DOK5,SLC19A2,EYA4,ZFYVE9,ISG20,TUBB4A,GSN,NSD1,MFSD9,PLAGL1,ZNF354A,TECPR2,STC2,LRP6,GULP1,PCK2,GFRA1,NTNG1,SLC16A10,PCSK5,PHC1 |
| 2.106e-02 | -3.86 | LANDIS_ERBB2_BREAST_TUMORS_324_DN | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_324_DN | 142 | 22 | 17377 | 1707 |
FADS1,SORBS1,ACSL1,IGFBP6,TMEM43,FZD4,GJB2,COL18A1,PDE8A,NPC2,GAS6,GNAI1,EIF4EBP1,GHR,LAMB1,FAM107B,TSC22D1,ACTA2,MARCKS,NRP1,PTGES,CES3 |
| 2.106e-02 | -3.86 | DAZARD_UV_RESPONSE_CLUSTER_G6 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G6 | 142 | 22 | 17377 | 1707 |
CREB3L2,EXPH5,MN1,VEGFC,MICAL2,BCL7A,RIN2,VLDLR,FERMT2,WWC1,CTBP2,FNDC3A,MTUS1,SMAD3,SLC7A1,FAT1,MAST4,FNBP1L,CEBPD,ATP2B1,TBC1D8,DOCK9 |
| 2.106e-02 | -3.86 | Lysine catabolism | REACTOME pathways | R-HSA-71064 | 12 | 4 | 10287 | 971 |
PHYKPL,HYKK,AADAT,AASS |
| 2.110e-02 | -3.86 | neuronal action potential | biological process | GO:0019228 | 30 | 7 | 17256 | 1658 |
SCN5A,KCNMB4,SCN2A,GRIK2,SCN8A,SCN3A,KCNMB3 |
| 2.110e-02 | -3.86 | positive regulation of cartilage development | biological process | GO:0061036 | 30 | 7 | 17256 | 1658 |
SMAD3,RUNX2,BMP4,BMPR2,ZNF219,BMP6,BMP1 |
| 2.110e-02 | -3.86 | response to arsenic-containing substance | biological process | GO:0046685 | 30 | 7 | 17256 | 1658 |
MAPK13,GSTO1,ATF3,ABCC2,ATF4,UROS,GSTO2 |
| 2.119e-02 | -3.85 | LCCL | smart domains | SM00603 | 6 | 3 | 9493 | 1056 |
DCBLD1,CRISPLD1,DCBLD2 |
| 2.119e-02 | -3.85 | C4 | smart domains | SM00111 | 6 | 3 | 9493 | 1056 |
COL4A5,COL4A3,COL4A4 |
| 2.120e-02 | -3.85 | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_DN | MSigDB lists | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_DN | 118 | 19 | 17377 | 1707 |
VEGFC,CARD6,ANTXR2,TCP11L2,CRIM1,HIP1,NRN1,SFXN3,IL18R1,TMEM74,SMAD3,TECPR1,FBXO32,KLF12,RAP2A,CNNM2,RASGRP1,NUDT17,NKX2-1 |
| 2.120e-02 | -3.85 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | 118 | 19 | 17377 | 1707 |
FARP1,ANKRD13D,RASAL2,ATP8A1,TNS1,ANKRD18A,KIF21B,FGFR1,MTUS1,RNF141,CPNE2,RPS6KA2,CDC14B,RALGAPA2,TMEM37,ALPK1,PLTP,LRP3,SLC16A10 |
| 2.123e-02 | -3.85 | GO_IMPORT_INTO_CELL | MSigDB lists | GO_IMPORT_INTO_CELL | 36 | 8 | 17377 | 1707 |
STEAP3,SLC1A3,SLC7A2,ATP1B1,SNAP25,STEAP1,ATP2B4,SNCA |
| 2.123e-02 | -3.85 | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN | MSigDB lists | CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN | 36 | 8 | 17377 | 1707 |
COL6A2,FBN1,EMILIN2,SEMA3C,PCOLCE2,JAM2,CDH2,SYK |
| 2.123e-02 | -3.85 | GO_OLFACTORY_LOBE_DEVELOPMENT | MSigDB lists | GO_OLFACTORY_LOBE_DEVELOPMENT | 36 | 8 | 17377 | 1707 |
DLX2,EOMES,ROBO2,SEMA3A,SLIT2,FGFR1,LRRK2,SKI |
| 2.123e-02 | -3.85 | GO_MULTIVESICULAR_BODY | MSigDB lists | GO_MULTIVESICULAR_BODY | 36 | 8 | 17377 | 1707 |
SLC40A1,BACE1,LRRK2,STEAP3,NDFIP2,RAB27B,LRAT,TPT1 |
| 2.123e-02 | -3.85 | ONGUSAHA_TP53_TARGETS | MSigDB lists | ONGUSAHA_TP53_TARGETS | 36 | 8 | 17377 | 1707 |
COL18A1,ERCC5,AK1,CCNG1,PLTP,PERP,CSRP2,DDIT4 |
| 2.124e-02 | -3.85 | GO_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT | MSigDB lists | GO_SKELETAL_MUSCLE_ORGAN_DEVELOPMENT | 126 | 20 | 17377 | 1707 |
BVES,ASS1,ATF3,DNER,SKI,FOXP2,MSC,HLF,EEF2,PLAGL1,EOMES,KCNAB1,HEYL,SVIL,COL19A1,MYH15,KLF5,DISP1,KLHL31,MEF2C |
| 2.124e-02 | -3.85 | RODWELL_AGING_KIDNEY_DN | MSigDB lists | RODWELL_AGING_KIDNEY_DN | 126 | 20 | 17377 | 1707 |
PRKAA2,AASS,KLHL3,ESRRG,SLK,SHANK2,C1orf226,ADCY1,B4GALNT3,PCLO,DCBLD2,GABARAPL1,ZNF711,ABCA5,CACNB2,GHR,MPPED2,KLF9,MORN4,CTH |
| 2.128e-02 | -3.85 | Glutamate Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-210500 | 24 | 6 | 10287 | 971 |
PPFIA4,SLC1A3,SNAP25,UNC13B,STXBP1,PPFIA2 |
| 2.133e-02 | -3.85 | human chr12q21.31 | chromosome location | human chr12q21.31 | 22 | 5 | 26185 | 1967 |
LIN7A,SLC6A15,LRRIQ1,OTOGL,PPFIA2 |
| 2.135e-02 | -3.85 | GO_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_PROTEOGLYCAN_BIOSYNTHETIC_PROCESS | 57 | 11 | 17377 | 1707 |
UST,CHSY3,BMPR2,XYLT1,HS3ST5,DSEL,CHSY1,HS3ST3B1,BCAN,GLCE,HS6ST3 |
| 2.135e-02 | -3.85 | GTGTCAA,MIR-514 | MSigDB lists | GTGTCAA,MIR-514 | 57 | 11 | 17377 | 1707 |
TRIM2,FZD4,MYO1B,NCOA7,SVIL,PRICKLE2,ENAH,PIK3C2B,TSPAN9,SCN3A,ZIC1 |
| 2.135e-02 | -3.85 | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | MSigDB lists | ZHENG_GLIOBLASTOMA_PLASTICITY_DN | 57 | 11 | 17377 | 1707 |
COL9A3,COL6A2,PLAGL1,ATP8A1,PPFIBP2,TSC22D1,NDRG2,PCOLCE2,SERPINH1,ZDHHC14,EPHB1 |
| 2.136e-02 | -3.85 | KRINGLE_1 | prosite domains | PS00021 | 16 | 5 | 12060 | 1278 |
HGF,ROR1,F12,PRSS12,KREMEN1 |
| 2.136e-02 | -3.85 | KRINGLE_2 | prosite domains | PS50070 | 16 | 5 | 12060 | 1278 |
HGF,ROR1,F12,PRSS12,KREMEN1 |
| 2.137e-02 | -3.85 | IL2_UP.V1_DN | MSigDB lists | IL2_UP.V1_DN | 175 | 26 | 17377 | 1707 |
RIN2,CACNG3,EHHADH,PNRC1,PRSS16,RHOBTB1,NKX3-2,CACNA1E,DEPTOR,GUCY1A2,SESN1,FAM110B,CBLN1,ZNF362,FUT9,MAP2K6,PRKG1,THAP10,TANC2,MAGI2,SNAI2,SCN3A,SNPH,ZNF629,PCSK5,ZNF391 |
| 2.139e-02 | -3.84 | membrane microdomain | cellular component | GO:0098857 | 305 | 40 | 18223 | 1724 |
MYO1D,SCN5A,SORBS1,BMPR2,GLIPR1L1,BVES,BACE1,CMTM8,LRP4,ADD2,EPHB1,LCP2,MLC1,NOS1AP,EEF2,LRP6,GRIP1,SERPINH1,ATP2B1,NOS3,CD55,RHOQ,TUBA1A,ANK2,LRRK2,ADCY1,PRKAR2B,ATP1B1,TLR6,GNAI1,PTPRC,MYADM,HPSE,TNFRSF1A,BMPR1A,UNC5B,CDH2,ATP2B4,CNTN1,STOM |
| 2.139e-02 | -3.84 | membrane raft | cellular component | GO:0045121 | 305 | 40 | 18223 | 1724 |
MYO1D,SCN5A,SORBS1,BMPR2,GLIPR1L1,BVES,BACE1,CMTM8,LRP4,ADD2,EPHB1,LCP2,MLC1,NOS1AP,EEF2,LRP6,GRIP1,SERPINH1,ATP2B1,NOS3,CD55,RHOQ,TUBA1A,ANK2,LRRK2,ADCY1,PRKAR2B,ATP1B1,TLR6,GNAI1,PTPRC,MYADM,HPSE,TNFRSF1A,BMPR1A,UNC5B,CDH2,ATP2B4,CNTN1,STOM |
| 2.142e-02 | -3.84 | transferase activity, transferring phosphorus-containing groups | molecular function | GO:0016772 | 1011 | 118 | 17224 | 1680 |
EPHA3,NMNAT3,BTC,NEK10,MVK,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,TENT5C,STK24,CDS1,MOK,SPEG,TGFBR3,RPS6KA2,TENT5A,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,PFKFB2,KCNH5,LRRK2,PANK1,PRKCQ,ACVR2B,FGF17,ROR1,SGK2,FRK,GRK3,FGFR1,MAGI3,TPK1,IRS2,DYRK1B,AK1,PRKCB,PTK7,PLK2,ERN1,MAP3K21,MAPK13,PIK3C2B,HGF,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,EFEMP1,IGF1R,PIK3AP1,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FES,PFKFB4,FGFR4,PAK1,HYKK,CRIM1,MPP1,EFNA3,NUAK2,OBSCN,AK4,STRADB,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,TERT,PELI2,MAP2K6,AKT3,MPP2,HK2,NEK11,PGM2L1,PIP5KL1,DLG2,LRRK1,HK1,CMPK2,MAP3K20,PANK3 |
| 2.144e-02 | -3.84 | GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | MSigDB lists | GO_EXTRACELLULAR_STRUCTURE_ORGANIZATION | 294 | 40 | 17377 | 1707 |
MPZL3,COL9A3,FN1,RECK,ITGA6,LAMC3,COL18A1,COL4A5,GAS6,BCAN,DDR1,SPINK5,COL14A1,COL27A1,ABI3BP,ITGB3,COL19A1,SH3PXD2B,SERPINH1,JAM2,COL9A2,CYP1B1,ITGB7,COL6A2,COL4A3,THSD4,COL4A4,JAM3,SNCA,MMP15,GSN,ADAMTS3,FBN1,ITGA2,LAMB1,BMP1,P4HA1,MMP16,B4GALT7,TLL2 |
| 2.149e-02 | -3.84 | cellular glucose homeostasis | biological process | GO:0001678 | 81 | 14 | 17256 | 1658 |
PRKAA2,IRS2,RAB11FIP5,UNC13B,IGF1R,ERN1,XBP1,HK2,PTPRN2,GAS6,HK1,RACK1,PCK2,PPARGC1A |
| 2.152e-02 | -3.84 | GO_LIPID_LOCALIZATION | MSigDB lists | GO_LIPID_LOCALIZATION | 251 | 35 | 17377 | 1707 |
PLA2G4A,PRKAA2,ACSL1,ATP9A,ATP8A1,LDLR,MSR1,STAT5B,ABHD4,SLCO3A1,SOAT2,ABCA5,FABP6,PRELID2,STARD4,PRELID1,LRP6,GULP1,PLTP,ABCC4,FZD4,SLC27A2,PLEKHA8,ACVR1C,VLDLR,ABCC2,ATP11A,NPC2,ATP10D,SPNS1,ENPP1,MFSD2A,OSBPL5,OSBPL6,ABCG1 |
| 2.160e-02 | -3.83 | regulation of myoblast differentiation | biological process | GO:0045661 | 51 | 10 | 17256 | 1658 |
CXCL10,ID3,RIPOR2,MSTN,PRICKLE1,BMP4,PLCB1,DDIT3,IGFBP3,MEF2C |
| 2.163e-02 | -3.83 | Ras | pfam domains | PF00071 | 135 | 21 | 17054 | 1666 |
RAB3B,RHOQ,RHOBTB1,RAB6B,RHOD,RASL11B,AGAP2,RASD1,RAB38,RAC3,RND2,RND3,RAP2A,RASD2,RAB26,RAB31,DIRAS1,GEM,RAB27B,RRAS2,RAB30 |
| 2.168e-02 | -3.83 | - | gene3d domains | 2.40.20.10 | 16 | 5 | 8148 | 867 |
HGF,F12,ROR1,PRSS12,KREMEN1 |
| 2.169e-02 | -3.83 | KIM_MYCN_AMPLIFICATION_TARGETS_UP | MSigDB lists | KIM_MYCN_AMPLIFICATION_TARGETS_UP | 87 | 15 | 17377 | 1707 |
BTC,NECAB1,L3MBTL4,CLYBL,PRSS12,LRP4,LRMP,PRRG1,SLC6A15,ST8SIA1,P2RY1,FAM81A,ENO1,CA13,HS6ST3 |
| 2.173e-02 | -3.83 | transmembrane transport | biological process | GO:0055085 | 1248 | 141 | 17256 | 1658 |
CACNG3,FLVCR2,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,CACNB4,SLCO3A1,SLC9A7,NCS1,KCNAB1,KCNN2,SLC16A2,SLC22A18,SLC10A7,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,GPM6A,KCNIP3,SLC3A2,SESN2,ABCC4,SLC9C1,ATOX1,SLC25A28,ABCC2,KCND3,SGK2,SFXN1,SPNS1,SLC7A1,KCNMB4,ATP7B,MFSD4A,SLC9B1,PRKAA2,KCNV1,SV2B,SCN5A,TMEM63C,GABRB2,SCN8A,SLC25A27,ATP6V1E2,SLC36A4,SLC1A3,GRPEL2,MCOLN2,SLC30A4,SLC7A11,ABCA5,CACNB2,SLC16A9,NIPAL2,SLCO4C1,FAM155A,NDUFA4L2,SLC37A1,KCNQ3,SLC36A1,RYR2,TTYH2,PEX5L,SLC46A3,STEAP1,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,CDH17,TRPC3,ADD2,SLC7A2,SLC19A2,SLC22A17,CHRNA5,STEAP3,FAM155B,SCN2A,ATP6AP1L,KCNB2,SCN3A,LRRC8B,KCNH5,SFXN4,SLC39A8,CHRNA6,ATP1B1,ASPH,ATP10D,GJC1,SLC39A14,ASIC1,KCNG1,DENND5B,ANO10,SLC6A9,GABRG2,SLC12A6,GABRR2,GAS6,SFXN3,KCNC4,MCU,SLC35F1,LRRC55,KCNJ4,SCN1B,GPR155,BHLHA15,KCNMB3,SGK3,SGK1,SLC6A15,SLC45A3,ATP2B1,TRPM4,SLC40A1,CACNA1E,GRID1,RASA3,PTPRC,MFSD9,SLC7A5,SLCO5A1,SLC18B1,GRIN2D,SLC22A15,SLC1A5,CACNA2D1,ATP2B4,DDIT3,SLC16A10,ABCG1,ATP1A3,SLC43A1 |
| 2.175e-02 | -3.83 | GSE25502_WT_VS_KLF13_KO_THYMIC_MEMORY_LIKE_CD8_TCELL_UP | MSigDB lists | GSE25502_WT_VS_KLF13_KO_THYMIC_MEMORY_LIKE_CD8_TCELL_UP | 167 | 25 | 17377 | 1707 |
ACVR1,MARK1,MSTN,GALNT12,PSTPIP2,ATP8A1,ELMOD1,SNTB1,IL18R1,HECTD2,HEG1,NUMBL,TIFA,GPRIN1,KLF12,MAGEA3,RAI14,PTPRN2,BNIP3,CYP2U1,IQGAP3,MAGEA6,C15orf41,PSPH,SNX7 |
| 2.175e-02 | -3.83 | GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_DN | MSigDB lists | GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_DN | 167 | 25 | 17377 | 1707 |
DBN1,TCP11L2,TBC1D8B,MPP1,C3orf52,PSD3,NRN1,LHPP,DDR1,ISG20,ID3,ABLIM1,AK1,IDI1,NAV1,KIAA1671,WFS1,PPFIBP1,P4HA2,PDE10A,TRPC1,DSEL,MYOM2,FHIT,RNF152 |
| 2.175e-02 | -3.83 | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN | 167 | 25 | 17377 | 1707 |
PFKFB4,ITGB7,MXI1,PNRC1,CYTH3,APBB1,LRMP,YPEL2,SORBS3,CBY1,SYNJ2BP,SESN1,HPCAL4,PLEKHB1,ID3,RIMKLB,TECPR1,C1orf21,KIAA0513,IPCEF1,PDE4D,ZFP36L2,ATP2B4,SNPH,PHC1 |
| 2.175e-02 | -3.83 | GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN | MSigDB lists | GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN | 167 | 25 | 17377 | 1707 |
EML5,TNIK,CD55,PDK1,SIDT1,ST6GAL1,RAPGEF4,TDRKH,PLEKHA1,SESN1,TTC28,KBTBD11,ID3,RALGPS2,MYC,INPP4B,RGS10,ADCY6,ZBTB20,IPCEF1,PACSIN1,RRAS2,RNF122,DIRC2,ABCG1 |
| 2.177e-02 | -3.83 | GO_BEHAVIOR | MSigDB lists | GO_BEHAVIOR | 498 | 63 | 17377 | 1707 |
CELSR1,PDE1B,FGF13,GRIK2,ATP8A1,EPS8,MCOLN3,GABRG2,BTBD9,ABAT,SLC1A3,P2RY1,NRXN1,APBA1,CACNB4,NOVA1,FOXP2,RNF180,KCNAB1,CHRNA5,BCHE,AFF2,RASD2,SGK1,FIG4,ETV1,ZNF385A,HMGCR,NKX2-1,MEIS2,USP2,FZD4,ADM2,LRRK2,VLDLR,SHANK2,GRID1,FGF12,ADCY1,SLITRK5,NLGN4X,PRKAR2B,SNAP25,SDK1,PLCB1,HOXA1,ZIC1,NEGR1,DKK1,SNCA,GPR37,CEBPB,GPRC5B,PLK2,GNAO1,THBS4,GRIN2D,TMOD2,OXTR,APBA2,NPHP1,ATP1A3,MEF2C |
| 2.179e-02 | -3.83 | KRIEG_HYPOXIA_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_VIA_KDM3A | 50 | 10 | 17377 | 1707 |
SLC7A1,FBXO32,INSIG1,FABP6,MARCH3,STEAP3,ASPH,PHLDA2,IL1RAP,RRAGD |
| 2.179e-02 | -3.83 | GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_BINDING | MSigDB lists | GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_BINDING | 50 | 10 | 17377 | 1707 |
SMAD3,INHBC,TGFBR3,MSTN,INHBE,BMP1,RASL11B,BMP4,SMAD6,BMP6 |
| 2.179e-02 | -3.83 | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | MSigDB lists | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | 50 | 10 | 17377 | 1707 |
CARS,SLC3A2,GARS,ASNS,ATF4,MYC,SLC7A5,WNT11,AARS,GPR161 |
| 2.179e-02 | -3.83 | REACTOME_APOPTOTIC_EXECUTION_PHASE | MSigDB lists | REACTOME_APOPTOTIC_EXECUTION_PHASE | 50 | 10 | 17377 | 1707 |
GSN,DSG2,PRKCD,PRKCQ,TJP1,VIM,SATB1,DSP,STK24,OCLN |
| 2.179e-02 | -3.83 | GYORFFY_MITOXANTRONE_RESISTANCE | MSigDB lists | GYORFFY_MITOXANTRONE_RESISTANCE | 50 | 10 | 17377 | 1707 |
LIN7A,PCDHB14,RASSF8,PHACTR2,AMOTL1,SLC30A4,POPDC3,ABI3BP,DOCK2,RRAGD |
| 2.182e-02 | -3.82 | WARTERS_IR_RESPONSE_5GY | MSigDB lists | WARTERS_IR_RESPONSE_5GY | 43 | 9 | 17377 | 1707 |
SH2D2A,BBC3,ATF3,CHADL,FAM198B,TNFRSF10C,FAM84B,THSD1,SESN1 |
| 2.182e-02 | -3.82 | GO_EXOCRINE_SYSTEM_DEVELOPMENT | MSigDB lists | GO_EXOCRINE_SYSTEM_DEVELOPMENT | 43 | 9 | 17377 | 1707 |
TFCP2L1,WLS,XBP1,RAB26,SEMA3C,NRP1,SEMA3A,FGFR1,IGSF3 |
| 2.182e-02 | -3.82 | VANHARANTA_UTERINE_FIBROID_UP | MSigDB lists | VANHARANTA_UTERINE_FIBROID_UP | 43 | 9 | 17377 | 1707 |
EFNB2,FN1,PRKCB,SATB2,COL9A2,ZFYVE9,TRPS1,HRASLS,IGSF3 |
| 2.182e-02 | -3.82 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | MSigDB lists | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | 43 | 9 | 17377 | 1707 |
KCNV1,KCND3,KCNQ3,KCNAB1,KCNC4,KCNH5,KCNG1,KCNB2,KCNS3 |
| 2.182e-02 | -3.82 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1 | 43 | 9 | 17377 | 1707 |
RUNX2,SLC7A11,ITGA2,REEP1,RASD1,SPRY4,ERRFI1,GEM,MAP1B |
| 2.182e-02 | -3.82 | ZHAN_MULTIPLE_MYELOMA_MF_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MF_UP | 43 | 9 | 17377 | 1707 |
ITGB7,ABLIM1,TYMP,TMEM37,COTL1,LCP2,FAM174B,TLR4,CEBPD |
| 2.182e-02 | -3.82 | chr10q25 | MSigDB lists | chr10q25 | 43 | 9 | 17377 | 1707 |
BAG3,ABLIM1,UROS,GSTO2,ITPRIP,SLK,RGS10,GSTO1,GFRA1 |
| 2.182e-02 | -3.82 | KRASNOSELSKAYA_ILF3_TARGETS_DN | MSigDB lists | KRASNOSELSKAYA_ILF3_TARGETS_DN | 43 | 9 | 17377 | 1707 |
MN1,UGT8,ASNS,HMGCS1,THBS4,SLC1A3,PCK2,GATM,PSPH |
| 2.182e-02 | -3.82 | GO_BODY_MORPHOGENESIS | MSigDB lists | GO_BODY_MORPHOGENESIS | 43 | 9 | 17377 | 1707 |
MSX1,ARID5B,LRP6,PLEKHA1,PAX9,ASPH,CRISPLD1,SKI,DKK1 |
| 2.183e-02 | -3.82 | purine ribonucleoside triphosphate binding | molecular function | GO:0035639 | 1796 | 200 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,RPS6KA2,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PRKG1,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,PRKCB,GBP1,PTK7,MAP3K21,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 |
| 2.186e-02 | -3.82 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_UP | 192 | 28 | 17377 | 1707 |
CREB3L2,LONRF1,ENAM,MXI1,ERGIC1,RUNX2,AGPAT4,FAM84A,SPATA6,LRP4,MSRB3,KCTD12,CBY1,SLC1A3,DOCK3,SNX9,TTC28,TBC1D30,TXNDC5,MECOM,PLAGL1,SH3RF1,PRKCB,KAZN,GAS2L3,BMP1,HSPA2,PSPH |
| 2.186e-02 | -3.82 | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | 192 | 28 | 17377 | 1707 |
RWDD2A,DOC2A,DBN1,GNG12,TBC1D1,ATOX1,IPO5,EPS8,MSR1,TTC30A,AK4,PDE8A,COL4A5,CHUK,TTC22,SNAP25,CD40,CACNB4,ATP10D,SNCA,GALNT1,CPVL,GHR,BBC3,MARCKS,ST8SIA1,MOXD1,CNTN1 |
| 2.186e-02 | -3.82 | GSE22886_DC_VS_MONOCYTE_UP | MSigDB lists | GSE22886_DC_VS_MONOCYTE_UP | 192 | 28 | 17377 | 1707 |
MRC2,EVL,AVPI1,RASAL2,FLVCR2,RNF170,DOCK1,GSTM4,HOMER2,DHCR24,TNS1,ISYNA1,GAS6,ATP1B1,DOCK3,SESN1,ABHD6,AARS,FAM162A,NT5DC2,GABARAPL1,QPRT,DAGLA,ID3,GSN,MAOA,TOX,LPP |
| 2.186e-02 | -3.82 | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_UP | MSigDB lists | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_UP | 192 | 28 | 17377 | 1707 |
SLC40A1,PXN,ALOX5AP,PNP,SLC36A1,GSTM4,EPS8,TNFAIP8L2,RASA3,MAFB,CEBPA,FAM117B,RNF44,KBTBD11,STK24,FGFR1,IFT81,OTUD1,RND3,MGAT1,GPR160,RAP2A,TMEM86A,ABI3,HPGD,KLF9,DBP,ZFP36L2 |
| 2.191e-02 | -3.82 | MAGI1 (membrane associated guanylate kinase, WW and PDZ domain containing 1) | protein interactions | 9223 | 100 | 17 | 17029 | 1718 |
CGN,LATS2,PHLDB2,RASAL2,PLEKHA5,RAPGEF2,CBY1,LPIN3,FAM110B,RPS6KA2,NAV1,MAP3K21,TFAP2A,SH3BP4,LARP1,SFN,GAB2 |
| 2.191e-02 | -3.82 | TAZ (tafazzin) | protein interactions | 6901 | 100 | 17 | 17029 | 1718 |
LATS2,COL6A2,B3GLCT,CNTNAP3,PLXNA2,COL18A1,LMLN,FRAS1,FAT1,VWDE,PAM,LRP6,MOXD1,GALNT18,PLTP,BTRC,CACNA2D1 |
| 2.193e-02 | -3.82 | regulation of BMP signaling pathway | biological process | GO:0030510 | 89 | 15 | 17256 | 1658 |
NBL1,MSX1,BMPR2,FBN1,RBPMS2,CHRDL1,ACVR2A,BMP4,SPART,SMAD6,PCSK6,SKI,DKK1,NEO1,FZD1 |
| 2.195e-02 | -3.82 | Glycerophospholipid catabolism | REACTOME pathways | R-HSA-6814848 | 7 | 3 | 10287 | 971 |
GDPD5,ENPP6,GDPD1 |
| 2.198e-02 | -3.82 | cellular response to external stimulus | biological process | GO:0071496 | 301 | 40 | 17256 | 1658 |
PRKAA2,BMPR2,IL15,ITGA6,CBS,GAS6,BMP6,STK24,BAG3,TLR3,ASNS,PMAIP1,BHLHA15,SREBF1,CADPS2,BNIP3,TLR4,ATP2B1,RNF152,FADS1,TRPM4,GDAP1,SESN2,ATF4,LRRK2,NUAK2,ATF3,WNT11,MARS,CD40,SESN1,BAIAP2,GABARAPL1,CTSV,ITGA2,XBP1,TNFRSF1A,PIK3C2B,ATG5,RRAGD |
| 2.199e-02 | -3.82 | RAC1 (Rac family small GTPase 1) | protein interactions | 5879 | 220 | 32 | 17029 | 1718 |
PRKN,FN1,DOCK1,PAK5,OPHN1,ENAH,LACC1,PRKCA,DOCK2,RAC3,NEDD4,ARHGAP44,CHN1,CHN2,MCF2L,PRKCD,PPP2R2B,IQGAP3,IL1RAP,DOCK8,PAK1,VAV3,CSN2,LRRK2,AGAP2,ARHGAP32,BAIAP2,SH3RF1,PLD1,IQSEC2,HACE1,STOM |
| 2.202e-02 | -3.82 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_GLYCOSYL_GROUPS | 260 | 36 | 17377 | 1707 |
CCDC126,GXYLT2,UGT8,GALNT6,GALNT12,ST6GAL1,XYLT1,ALG1L,GALNT13,CHSY1,MGAT5B,QPRT,GALNT1,TYMP,GBGT1,PRTFDC1,FUT9,MGAT1,ST8SIA1,AGL,ALG10B,B4GALT6,PARP9,CHSY3,B3GALT1,GCNT2,PNP,MGAT4B,ST6GALNAC3,B4GALNT3,GALNT14,DPY19L2,GALNT3,B3GALT2,ALG11,B4GALT7 |
| 2.204e-02 | -3.81 | GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL | MSigDB lists | GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL | 72 | 13 | 17377 | 1707 |
CXCL10,GSTM2,ANK2,UBASH3B,PTPN6,JPH1,RYR2,TRPC1,GSTO1,PDE4D,ATG5,ASPH,SNCA |
| 2.204e-02 | -3.81 | GO_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT | MSigDB lists | GO_EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT | 72 | 13 | 17377 | 1707 |
COL9A3,COL4A3,FBN1,COL4A4,EMILIN2,LAMB1,TUFT1,COL19A1,COL4A5,BCAN,COL14A1,COL9A2,COL27A1 |
| 2.204e-02 | -3.81 | chr2q31 | MSigDB lists | chr2q31 | 72 | 13 | 17377 | 1707 |
CHN1,B3GALT1,PDK1,BMPR2,KLHL23,GPR155,ITGA6,RAPGEF4,MYO3B,TTC30A,HOXD13,TTC30B,METAP1D |
| 2.204e-02 | -3.81 | GO_MULTICELLULAR_ORGANISMAL_MACROMOLECULE_METABOLIC_PROCESS | MSigDB lists | GO_MULTICELLULAR_ORGANISMAL_MACROMOLECULE_METABOLIC_PROCESS | 72 | 13 | 17377 | 1707 |
MMP15,MRC2,ID1,COL6A2,COL4A3,ADAMTS3,COL4A4,COL25A1,COL18A1,COL19A1,COL4A5,SERPINH1,MMP16 |
| 2.204e-02 | -3.81 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | molecular function | GO:0001227 | 236 | 33 | 17224 | 1680 |
KLF8,MXI1,JDP2,GATA3,BCL6B,ZNF219,SATB1,TRPS1,NKX6-1,FOXP2,IKZF5,BCL6,TFAP2A,YBX3,GFI1,ENO1,GLIS1,SNAI2,MSX1,KCNIP3,NKX3-2,ARID5B,ATF3,PRDM1,ZFPM2,BATF3,BCL11A,CEBPB,MSC,BACH2,NACC2,ZBTB20,PURG |
| 2.205e-02 | -3.81 | monocarboxylic acid metabolic process | biological process | GO:0032787 | 491 | 61 | 17256 | 1658 |
PLA2G4A,PRKAA2,UST,ACSL1,ALOX5AP,ELOVL4,ENO2,EHHADH,CYP2J2,OLAH,ELOVL7,CYP4V2,STAT5B,SCD,ABAT,SLC1A3,BCAN,LPIN3,PHGDH,CYP26A1,ASNS,MSMO1,FAAH2,ALDOC,GHR,PCK2,ENO1,CYP1B1,FADS1,VNN2,GAPDH,GSTM2,SESN2,SLC27A2,PFKFB2,ELOVL3,HACD1,FASN,OGDHL,ABCC2,PRKAR2B,AIG1,AMDHD1,SNCA,DAGLA,ALDOA,XBP1,BDH2,TNFRSF1A,PAM,HK2,HPGD,PGM2L1,DSEL,HK1,CYP2U1,PPARGC1A,PTGES,OSBPL6,ACSM3,CRYL1 |
| 2.206e-02 | -3.81 | USP54 (ubiquitin specific peptidase 54) | protein interactions | 159195 | 42 | 9 | 17029 | 1718 |
CCNJL,LATS2,LGR4,SKAP1,THSD4,P4HA2,BTRC,CHMP4C,CRYL1 |
| 2.206e-02 | -3.81 | MMP9 (matrix metallopeptidase 9) | protein interactions | 4318 | 42 | 9 | 17029 | 1718 |
BTC,COL6A2,COL4A3,FN1,RECK,COL4A4,COL18A1,COL4A5,COL14A1 |
| 2.208e-02 | -3.81 | body morphogenesis | biological process | GO:0010171 | 44 | 9 | 17256 | 1658 |
MSX1,ARID5B,LRP6,PLEKHA1,PAX9,ASPH,CRISPLD1,SKI,DKK1 |
| 2.208e-02 | -3.81 | regulation of cAMP-mediated signaling | biological process | GO:0043949 | 44 | 9 | 17256 | 1658 |
CXCL10,PDE10A,RAPGEF2,RASD2,ADRB1,PEX5L,PRKCA,ATP2B4,GNAI1 |
| 2.210e-02 | -3.81 | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_DN | MSigDB lists | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_DN | 159 | 24 | 17377 | 1707 |
FADS1,TCP11L2,LGALS3,ST14,SEC24D,SLC36A1,TMEM65,SFXN3,PKN1,ZDHHC14,GSN,FBXO32,TMEM154,MAP2K6,LRRIQ3,EMILIN2,XBP1,RAB31,MARCH3,STEAP3,LMAN2,IPCEF1,TPM1,AGL |
| 2.210e-02 | -3.81 | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_DN | MSigDB lists | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_DN | 159 | 24 | 17377 | 1707 |
TRDMT1,MTG1,MXI1,MVK,SCAMP1,LDLR,DNAJC6,TNFAIP8L2,ARL2,LHPP,GPSM2,IL18R1,TBC1D19,RNF141,HMGCS1,INSIG1,MSMO1,ADCK1,MAP2K6,DYNC2LI1,CAB39L,MARCKS,RNF130,CRYL1 |
| 2.210e-02 | -3.81 | GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_C57BL6_DN | MSigDB lists | GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_C57BL6_DN | 159 | 24 | 17377 | 1707 |
ARHGAP26,EPB41L5,ATL1,CLYBL,AASS,TCF24,NPM3,MCF2L2,CYTH3,AK4,ARRDC4,FNDC3A,PAGE5,NAV1,LMLN,MPPED2,SH3BP4,RCN3,NAP1L3,PIK3C2B,HRK,SP140,MME,NOS3 |
| 2.211e-02 | -3.81 | L-type voltage-gated calcium channel complex | cellular component | GO:1990454 | 7 | 3 | 18223 | 1724 |
CACNB2,NOS1AP,CACNA2D1 |
| 2.211e-02 | -3.81 | collagen network | cellular component | GO:0098645 | 7 | 3 | 18223 | 1724 |
COL4A5,COL4A3,COL4A4 |
| 2.211e-02 | -3.81 | presynaptic cytoskeleton | cellular component | GO:0099569 | 7 | 3 | 18223 | 1724 |
SEPT3,PCLO,RIMS2 |
| 2.211e-02 | -3.81 | network-forming collagen trimer | cellular component | GO:0098642 | 7 | 3 | 18223 | 1724 |
COL4A5,COL4A3,COL4A4 |
| 2.211e-02 | -3.81 | basal dendrite | cellular component | GO:0097441 | 7 | 3 | 18223 | 1724 |
SH3GL2,MAP2,MAP1B |
| 2.213e-02 | -3.81 | RhoGAP | smart domains | SM00324 | 64 | 13 | 9493 | 1056 |
CHN1,ARHGAP26,ARHGAP21,CHN2,ARAP2,ARHGAP22,OPHN1,SRGAP1,ARHGAP28,ARHGAP32,FAM13A,ARHGAP44,SYDE2 |
| 2.213e-02 | -3.81 | regulation of protein maturation | biological process | GO:1903317 | 113 | 18 | 17256 | 1658 |
CD55,CFH,C4A,LRRK2,CR2,C1R,F12,CHAC1,GAS1,C4BPB,GSN,CCBE1,CFHR1,MAGEA3,PROS1,SUSD4,ENO1,PRKACB |
| 2.214e-02 | -3.81 | actin cytoskeleton reorganization | biological process | GO:0031532 | 66 | 12 | 17256 | 1658 |
PAK1,GSN,FER,TNIK,FRY,GPR65,PTK7,RAP2A,CTTN,CDC42BPA,NRP1,RAC3 |
| 2.216e-02 | -3.81 | human chr3q27.2 | chromosome location | human chr3q27.2 | 15 | 4 | 26185 | 1967 |
IGF2BP2,C3orf70,NMRAL2P,EHHADH |
| 2.218e-02 | -3.81 | human chr3q13.2 | chromosome location | human chr3q13.2 | 30 | 6 | 26185 | 1967 |
CFAP44,PHLDB2,SIDT1,GCSAM,SLC9C1,C3orf52 |
| 2.219e-02 | -3.81 | DYNLL2 (dynein light chain LC8-type 2) | protein interactions | 140735 | 63 | 12 | 17029 | 1718 |
DLGAP1,PAK1,DZANK1,LCA5,SHANK2,WWC1,FAM117B,DLG2,THAP10,SKAP1,DYNC1I1,HOMER3 |
| 2.219e-02 | -3.81 | ATF3 (activating transcription factor 3) | protein interactions | 467 | 63 | 12 | 17029 | 1718 |
CEBPB,SMAD3,ID3,ATF4,FHL2,ATF3,CEBPA,DBP,BATF,DOK5,DDIT3,BATF3 |
| 2.220e-02 | -3.81 | Ion channel transport | REACTOME pathways | R-HSA-983712 | 209 | 29 | 10287 | 971 |
TRPM4,ANO10,SLC9C1,ATP9A,GABRB2,ATP8A1,MCOLN3,ATP6V1E2,TTYH2,GABRG2,RYR2,GABRR2,ATP11A,ATP1B1,SGK2,ASPH,ATP10D,MCOLN2,ATP7B,ASIC1,SGK3,SGK1,TRPC1,TRPC3,SLC9B1,ATP2B1,ATP2B4,ATP1A3,STOM |
| 2.220e-02 | -3.81 | Small_GTPase | interpro domains | IPR001806 | 135 | 21 | 18492 | 1811 |
RAB3B,RHOQ,RHOBTB1,RHOD,RAB6B,RASL11B,AGAP2,RASD1,RAB38,RAC3,RND2,RND3,RAP2A,RASD2,RAB26,RAB31,DIRAS1,GEM,RAB27B,RRAS2,RAB30 |
| 2.221e-02 | -3.81 | negative regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001237 | 105 | 17 | 17256 | 1658 |
ACVR1,LGALS3,PAK5,ITGA6,YAP1,STRADB,EYA4,SH3RF1,TERT,SGK3,HGF,CTTN,BMP4,NRP1,UNC5B,SNAI2,NOS3 |
| 2.225e-02 | -3.81 | regulation of microtubule cytoskeleton organization | biological process | GO:0070507 | 171 | 25 | 17256 | 1658 |
PAK1,PRKAA2,EPHA3,PHLDB2,TMEM67,FGF13,CKAP2,ARL2,NPM1,HDGFL3,GPSM2,MAP1B,SNCA,GNAI1,FSD1,TUBB4A,RANBP2,MAP1A,MAP2,PLK2,MAP9,MET,MID1,FES,CHMP4C |
| 2.227e-02 | -3.80 | regulation of calcium ion transport | biological process | GO:0051924 | 231 | 32 | 17256 | 1658 |
LGALS3,UBASH3B,LILRB1,CACNB4,NOS1AP,CACNB2,EHD3,STC2,TRPC1,TSPAN13,PDE4D,HSPA2,PDGFRB,NOS3,GSTM2,ANK2,PTPN6,JPH1,HOMER2,PACSIN3,RYR2,GSTO1,ATP1B1,SNCA,HOMER3,CXCL10,WFS1,GNAO1,ATG5,GEM,TRPC3,CACNA2D1 |
| 2.231e-02 | -3.80 | vif (p23) | protein interactions | 155459 | 364 | 49 | 17029 | 1718 |
PRKAA2,MVK,RUNX2,GLIPR1L1,ITGA6,XYLT1,LDLR,KIAA1217,NEDD4,F3,GATA2,SP140,ERRFI1,SLIT2,GFRA1,PERP,PRKACB,SCN3A,ULBP1,DUSP1,EIF4E3,FASN,LITAF,TTC30A,CR2,PHACTR2,PRKAR2B,VIM,TTC28,PLCB1,MAP1B,TPK1,CEBPB,ICA1,IKZF3,PLAGL1,INSIG1,ADAMTS3,RND3,ISM1,CSF1,CCNA1,UACA,TNFSF15,DHCR7,SLFN5,IL9R,PURG,MME |
| 2.234e-02 | -3.80 | cellular response to peptide hormone stimulus | biological process | GO:0071375 | 266 | 36 | 17256 | 1658 |
GNG12,SORBS1,ATP6V1E2,ASS1,STAT5B,NKX6-1,CA2,IGF1R,PRKCD,GHR,SREBF1,ADCY6,ERRFI1,PCK2,TSHR,PRKACB,PAK1,FER,PXN,RHOQ,NR4A1,ADCY1,MARS,PRKAR2B,BAIAP2,CPEB1,GPLD1,IRS2,ENPP1,TRIB3,FBN1,GNB4,EIF4EBP1,XBP1,RAB31,TBC1D4 |
| 2.235e-02 | -3.80 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | 184 | 27 | 17377 | 1707 |
CREB3L2,PDLIM7,MEIS2,FGF13,GLIPR1L1,RIMKLA,ARHGAP22,PPFIBP2,SDC3,WDFY4,C3orf70,CANX,FAM162A,GLCE,MSC,ARHGAP21,LMLN,RNF217,ALDOC,PRELID2,XBP1,NCOA7,DSEL,SH3PXD2B,MET,RNF157,LARP1 |
| 2.235e-02 | -3.80 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_DN | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_DN | 184 | 27 | 17377 | 1707 |
BCL11B,MAN2B2,IL17RD,C2orf88,THOC5,ANKRD13B,KDM5B,ARHGEF11,NR4A1,JDP2,CYP4V2,DUSP9,ITPR2,CDC42BPA,AHRR,FKBP9,TLR3,GRHL1,EHD3,TMEM86A,PTPRN2,INPP5F,DLX2,DISP2,AGL,TESC,ZFP36L2 |
| 2.235e-02 | -3.80 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 184 | 27 | 17377 | 1707 |
CREB3L2,PXN,MARK1,STAT4,CBY1,NPC2,PLEKHA1,PYGO1,PRKCA,SEL1L3,INPP1,LGI2,NELL2,ASNS,NACC2,CDC14B,WFS1,SVIL,DHRS12,RNF130,TBC1D4,NR3C2,CKAP4,CRYL1,DOCK9,DUSP1,SNPH |
| 2.235e-02 | -3.80 | GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_UP | MSigDB lists | GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_UP | 184 | 27 | 17377 | 1707 |
CXCR5,GPT2,SERINC5,KLHL4,JDP2,MPP1,GSTM4,UBAC2,MEF2B,AK4,ARL2,CEBPA,FAM162A,EPDR1,MAPKAPK2,SH3RF1,ALDOC,TMEM86A,BCL6,SFMBT1,SLC22A15,STXBP1,RNF157,DHCR7,SNAI2,CTNND2,LPP |
| 2.235e-02 | -3.80 | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_DN | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_DN | 184 | 27 | 17377 | 1707 |
NECAB2,SLC37A1,TCTN2,DCC,ST6GAL1,FBXO36,ZDHHC14,DOCK5,FAM162A,COL27A1,EPCAM,RNF150,SLC30A4,NCKAP1L,COL25A1,MYC,MAP9,THSD7B,SLCO5A1,KIAA1614,DIRAS1,LIMCH1,MAPK13,FHIT,TNFRSF11A,SEMA6C,SIX2 |
| 2.235e-02 | -3.80 | GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_UP | MSigDB lists | GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_UP | 184 | 27 | 17377 | 1707 |
EHHADH,PNRC1,SEC24D,FOXN3,IPO5,ZDHHC15,PKP2,IL13RA1,C3orf70,NDFIP2,PHGDH,RNF44,ABHD4,PFN2,DOCK2,AMDHD1,GABARAPL1,GPR150,CD37,MAP2,CLDN12,PRKCD,SERPINI1,SLC22A15,HK1,VGLL4,HMGCR |
| 2.235e-02 | -3.80 | GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN | MSigDB lists | GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN | 184 | 27 | 17377 | 1707 |
MXI1,TCP11L2,SIDT1,LPCAT2,SPATA6,TNFAIP8L2,BNIP3L,SELL,RASA3,MSRB3,SLC12A6,DENND3,DOCK2,PGAP1,RERE,HPSE,AKT3,C1orf21,ITGB3,TMEM86A,ABI3,FAM107B,TSPAN13,DENND1C,PTPRE,SYK,SMPDL3A |
| 2.235e-02 | -3.80 | GSE30083_SP1_VS_SP2_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP2_THYMOCYTE_UP | 184 | 27 | 17377 | 1707 |
ARHGAP26,SLC3A2,PODXL2,ALDH2,ENO2,AGPAT4,JPH1,LMCD1,C1R,RASD1,PRKAR2B,TDRKH,ZNF711,CXCL10,PLXDC2,SH3BP4,HK2,SGK1,LAPTM4B,MARCKS,RNF130,LRRK1,TMEM120B,CACNA2D1,PDGFRB,HEY1,STOM |
| 2.235e-02 | -3.80 | GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_NAIVE_CD8_TCELL_DN | 184 | 27 | 17377 | 1707 |
UST,EVL,ZNF516,USP2,EHHADH,TUBE1,CHUK,PRDM1,ATP11A,LCP2,NDFIP2,LDHD,TMCO3,NAV1,MGAT1,CNKSR3,SLC2A6,XBP1,BCL6,MAP7,DLG2,LMAN2,DLX2,LOXL4,CMPK2,RRAGD,HMGCR |
| 2.235e-02 | -3.80 | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN | MSigDB lists | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN | 184 | 27 | 17377 | 1707 |
ARHGAP26,COL9A3,MOCOS,MYO1D,SH3BP2,RHOBTB1,LPCAT2,PSTPIP2,LRMP,TCEA3,ELMOD1,GATA3,GSTO1,KIAA1217,KIF21B,PALLD,FAM110B,NEDD4,RND2,SPNS1,SH3GL2,GATA2,RND3,RGS10,CMPK2,GFI1,RRAGD |
| 2.235e-02 | -3.80 | GSE3982_EOSINOPHIL_VS_DC_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_DN | 184 | 27 | 17377 | 1707 |
MRC2,ALDH2,CELSR1,PNP,HEBP1,ACO1,ATF3,SCD,PALLD,SESN1,ASPH,FAM162A,PPP2R3A,SLC39A14,TMEM53,CHN2,NACC2,ABI3BP,KMO,PEMT,CCNA1,RAI14,PIK3C2B,PCK2,VWA5A,ENO1,PCSK5 |
| 2.235e-02 | -3.80 | GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP | MSigDB lists | GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_UP | 184 | 27 | 17377 | 1707 |
PCDH18,TMEM63C,MYCBP2,SV2B,SYNPO2,ANKRD13B,FAM131C,GJB2,NLRP14,ADAMTS6,DYNC1I1,TTC28,SPINK5,CA13,COL27A1,RERE,CXCL10,MSC,PCDHB7,FBN1,SLC22A18,COL19A1,ST8SIA1,CMPK2,DNAH5,NPHP1,ATP1A3 |
| 2.235e-02 | -3.80 | B41 | smart domains | SM00295 | 51 | 11 | 9493 | 1056 |
FRMPD3,EPB41L5,EPB41L3,PLEKHH2,FARP1,MYO10,PTPN13,PTPN21,FERMT2,TLN2,FRMD5 |
| 2.239e-02 | -3.80 | oxaloacetate metabolic process | biological process | GO:0006107 | 12 | 4 | 17256 | 1658 |
STAT5B,MDH1B,PCK2,GHR |
| 2.239e-02 | -3.80 | hepatocyte growth factor receptor signaling pathway | biological process | GO:0048012 | 12 | 4 | 17256 | 1658 |
PAK1,HGF,NRP1,MET |
| 2.239e-02 | -3.80 | epithelial to mesenchymal transition involved in endocardial cushion formation | biological process | GO:0003198 | 12 | 4 | 17256 | 1658 |
MSX1,BMP4,HEYL,SNAI2 |
| 2.239e-02 | -3.80 | pulmonary valve morphogenesis | biological process | GO:0003184 | 12 | 4 | 17256 | 1658 |
BMP4,SMAD6,HEYL,HEY1 |
| 2.239e-02 | -3.80 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902237 | 12 | 4 | 17256 | 1658 |
ATF3,ATF4,PMAIP1,DDIT3 |
| 2.239e-02 | -3.80 | I-kappaB phosphorylation | biological process | GO:0007252 | 12 | 4 | 17256 | 1658 |
DAB2IP,CHUK,TLR3,TLR4 |
| 2.239e-02 | -3.80 | regulation of high voltage-gated calcium channel activity | biological process | GO:1901841 | 12 | 4 | 17256 | 1658 |
GEM,CACNB2,NOS1AP,CACNA2D1 |
| 2.239e-02 | -3.80 | pulmonary valve development | biological process | GO:0003177 | 12 | 4 | 17256 | 1658 |
BMP4,SMAD6,HEYL,HEY1 |
| 2.239e-02 | -3.80 | fatty acid elongation | biological process | GO:0030497 | 12 | 4 | 17256 | 1658 |
ELOVL4,ELOVL7,ELOVL3,HACD1 |
| 2.239e-02 | -3.80 | response to leucine | biological process | GO:0043201 | 12 | 4 | 17256 | 1658 |
SESN2,PPARGC1A,SESN1,RRAGD |
| 2.239e-02 | -3.80 | lysine catabolic process | biological process | GO:0006554 | 12 | 4 | 17256 | 1658 |
PHYKPL,HYKK,AADAT,AASS |
| 2.240e-02 | -3.80 | regulation of epithelial cell proliferation | biological process | GO:0050678 | 373 | 48 | 17256 | 1658 |
BCL11B,SCN5A,ID1,BMPR2,GATA3,OVOL2,PRKCA,BMP6,F3,FOXP2,RIDA,TGFBR3,GATA2,DLX6,MYC,ITGB3,DAB2IP,KLF9,IQGAP3,ERRFI1,SNAI2,GLI1,INTU,VEGFC,ATP5IF1,KDM5B,TGFA,NR4A1,YAP1,SYNJ2BP,SAV1,FGFR1,SMAD3,THBS4,APELA,AKT3,CTSV,LAMB1,XBP1,MCC,EGFL7,BMPR1A,BMP4,VASH2,NRP1,NKX2-8,SFN,MEF2C |
| 2.241e-02 | -3.80 | Serotonin Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-181429 | 18 | 5 | 10287 | 971 |
PPFIA4,SNAP25,UNC13B,STXBP1,PPFIA2 |
| 2.245e-02 | -3.80 | dermatan sulfate biosynthesis | BIOCYC pathways | META_PWY-6571 | 15 | 5 | 902 | 105 |
CHSY3,UST,CHSY1,B4GALT7,XYLT1 |
| 2.246e-02 | -3.80 | GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_INORGANIC_ION_TRANSMEMBRANE_TRANSPORT | 544 | 68 | 17377 | 1707 |
CACNG3,MCOLN3,ITPR2,CACNB4,NCS1,SLC9A7,KCNN2,KCNAB1,KCNS3,TRPC1,TMEM37,SCN2A,ATP6AP1L,SCN3A,KCNB2,GPM6A,SLC3A2,KCNIP3,KCNH5,SLC39A8,ATOX1,ATP1B1,KCND3,ASPH,SLC39A14,KCNMB4,ATP7B,KCNG1,BBC3,SLC9B1,DENND5B,KCNV1,PRKAA2,SCN5A,ANO10,SCN8A,GABRB2,ATP6V1E2,GABRG2,SLC12A6,GAS6,GABRR2,KCNC4,MCU,MCOLN2,KCNJ4,SLC30A4,SCN1B,CACNB2,KCNMB3,ATP2B1,TRPM4,SLC40A1,KCNQ3,SLC37A1,SLC36A1,CACNA1E,RASA3,RYR2,TTYH2,PTPRC,KCNK15,TMCO3,TRPC3,CACNA2D1,ATP2B4,DDIT3,ATP1A3 |
| 2.247e-02 | -3.80 | response to hexose | biological process | GO:0009746 | 146 | 22 | 17256 | 1658 |
PRKAA2,SESN2,COL6A2,ACVR1C,PFKFB2,GAS6,ACVR2B,RACK1,ILDR2,GPLD1,NKX6-1,RAB11FIP5,IRS2,UNC13B,IGF1R,CTSV,ERN1,XBP1,SREBF1,PTPRN2,PPARGC1A,PCK2 |
| 2.247e-02 | -3.80 | GO_GUANYL_NUCLEOTIDE_BINDING | MSigDB lists | GO_GUANYL_NUCLEOTIDE_BINDING | 365 | 48 | 17377 | 1707 |
MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,RASL11B,TUBE1,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,PDE10A,EHD3,RASD2,RAP2A,RAB26,PRKG1,PRKG2,PCK2,ARL4D,RAB27B,RRAS2,SEPT3,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,RAPGEF2,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GBP1,GNAO1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,RRAGD |
| 2.248e-02 | -3.80 | MORF_CAMK4 | MSigDB lists | MORF_CAMK4 | 269 | 37 | 17377 | 1707 |
RUNX2,STXBP5L,CFH,GABRB2,LRP4,RGS7,FAM13A,PRKCA,NOVA1,TPD52L1,COL14A1,PPM1E,SOAT2,TACC2,COL19A1,PDE4D,ST8SIA1,MYT1,NEB,B4GALT6,GCA,KLHL23,WISP3,COL4A4,CDC42BPA,SLC46A3,GPR19,PLEKHB1,GPLD1,ZNF266,MAP2,ITGBL1,PAX9,TANC2,NR3C2,SMYD3,CACNA2D1 |
| 2.248e-02 | -3.80 | V$TATA_C | MSigDB lists | V$TATA_C | 269 | 37 | 17377 | 1707 |
BCL11B,SETBP1,RASL11B,CUEDC2,FOXG1,SATB1,NEDD4,MECOM,NKX6-1,RTN1,PPM1E,KCTD15,CA2,EEF2,BNIP3,ERRFI1,PDGFRB,BDNF,HNF4G,AGPAT4,ESRRG,PANK1,SHANK2,PACSIN3,ATF3,PRKAR2B,PRDM1,ATOH1,FBXO36,AMDHD1,NAALADL2,HERPUD1,SVIL,SEMA3A,HOXB9,MAPK10,PKIA |
| 2.248e-02 | -3.80 | actin filament binding | molecular function | GO:0051015 | 177 | 26 | 17224 | 1680 |
MYO1D,MYO10,DSTN,MYO1B,HIP1,ADD2,PLS1,ADSSL1,PPP1R9A,CTNNA2,PLS3,SCIN,GSN,ABLIM1,EEF2,WIPF3,CACNB2,POF1B,SVIL,MYOM2,MYH15,MARCKS,TPM1,TLN2,MYO6,SHTN1 |
| 2.253e-02 | -3.79 | lipid biosynthetic process | biological process | GO:0008610 | 584 | 71 | 17256 | 1658 |
PLA2G4A,TFCP2L1,MVK,ACSL1,UGT8,ELOVL4,LPCAT2,LPIN3,CDS1,CYP51A1,PLPP1,IDI1,ERG28,B3GALT1,CYB5R2,MVD,PLPP2,HACD1,PLEKHA1,FGF17,ETNPPL,FGFR1,IRS2,INSIG1,PEMT,INPP4B,B3GALT2,HPGD,PIK3C2B,INPP5F,MBOAT2,PRKAA2,SERINC5,INPPL1,ALOX5AP,ELOVL7,DHCR24,OLAH,SCD,ISYNA1,PGAP1,GBGT1,HMGCS1,MSMO1,SREBF1,FIG4,ST8SIA1,CERS4,PCK2,HMGCR,B4GALT6,FGFR4,FADS1,PLEKHA8,SLC27A2,PTPN13,AGPAT4,ELOVL3,FASN,ST6GALNAC3,MFSD2A,ACER2,XBP1,SRD5A3,SQLE,PLD1,CERS1,DHCR7,OSBPL6,PTGES,ACSM3 |
| 2.254e-02 | -3.79 | INPP5E (inositol polyphosphate-5-phosphatase E) | protein interactions | 56623 | 56 | 11 | 17029 | 1718 |
CGN,PHLDB2,NAV1,RALGPS2,RASAL2,PTPN13,MAP3K21,CBY1,LPIN3,TANC2,OSBPL6 |
| 2.254e-02 | -3.79 | MMP2 (matrix metallopeptidase 2) | protein interactions | 4313 | 56 | 11 | 17029 | 1718 |
COL6A2,EDA,LGALS3,FN1,BACE1,ITGB3,COL18A1,BCAN,COL14A1,FGFR1,IGFBP3 |
| 2.255e-02 | -3.79 | LDLRAD4 (low density lipoprotein receptor class A domain containing 4) | protein interactions | 753 | 49 | 10 | 17029 | 1718 |
SMAD3,ANKRD13D,HECW2,ACVR2A,YAP1,ACVR2B,WWC2,MAGI3,NEDD4,FGFR1 |
| 2.256e-02 | -3.79 | CDC25C (cell division cycle 25C) | protein interactions | 995 | 108 | 18 | 17029 | 1718 |
CGN,PHLDB2,RASAL2,PTPN13,CTBP2,CBY1,LPIN3,PKN1,NEDD4,CDS1,FAM27E3,NAV1,RALGPS2,MAP3K21,TANC2,LZTS1,OSBPL6,SFN |
| 2.256e-02 | -3.79 | PAK2 (p21 (RAC1) activated kinase 2) | protein interactions | 5062 | 108 | 18 | 17029 | 1718 |
PAK1,SORBS1,PACSIN3,VIM,SORBS3,SNX9,DOCK2,FSD1,SH3GL2,EEF2,SH3RF1,MYC,PLK2,ABI3,MYO6,NPHP1,SFN,THOC3 |
| 2.266e-02 | -3.79 | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | 103 | 17 | 17377 | 1707 |
KCNIP3,NKX3-2,JDP2,GATA3,ATF3,PRDM1,ZFPM2,ZNF219,BATF3,BCL11A,FOXP2,NKX6-1,NACC2,TFAP2A,ZBTB20,GFI1,SNAI2 |
| 2.270e-02 | -3.79 | GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 201 | 29 | 17377 | 1707 |
PAK1,NEK10,AVPI1,FZD4,TGFA,FZD8,LRRK2,DUSP9,NTRK3,PKN1,CD40,TLR6,TPD52L1,FGFR1,MAPKAPK2,MAP2K6,GHR,ERN1,DUSP19,HGF,DIRAS1,DAB2IP,IQGAP3,MAPK10,TLR4,TNFRSF11A,SYK,RASGRP1,PDGFRB |
| 2.274e-02 | -3.78 | TP53 Regulates Transcription of Cell Death Genes | REACTOME pathways | R-HSA-5633008 | 45 | 9 | 10287 | 971 |
PMAIP1,PRELID1,BNIP3L,BCL6,BBC3,STEAP3,TNFRSF10C,PERP,IGFBP3 |
| 2.274e-02 | -3.78 | Non-integrin membrane-ECM interactions | REACTOME pathways | R-HSA-3000171 | 45 | 9 | 10287 | 971 |
ITGA6,ITGB3,LAMB1,ITGA2,LAMC3,SDC3,PRKCA,NRXN1,DDR1 |
| 2.279e-02 | -3.78 | - | gene3d domains | 4.10.740.10 | 11 | 4 | 8148 | 867 |
PRRG1,PROS1,GAS6,PRRG4 |
| 2.281e-02 | -3.78 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_6H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_6H_UP | 176 | 26 | 17377 | 1707 |
VNN2,CD55,SESN2,ANKRD13D,GALNT6,TGFA,CYB5R2,LILRB1,DENND3,TBC1D30,DDIT4,BCL11A,IRS2,PIK3AP1,TECPR2,EMILIN2,RAB31,HS3ST3B1,SH3PXD2B,PLD1,PTGES,SYK,KIAA1211,SMPDL3A,DIRC2,SLC16A10 |
| 2.281e-02 | -3.78 | GSE2706_UNSTIM_VS_2H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_R848_DC_DN | 176 | 26 | 17377 | 1707 |
ACSL1,MYO10,REL,RAPGEF2,STAT4,TTYH2,SHISA2,HERC6,DENND3,ISG20,GALNT3,SLC7A1,MCOLN2,CXCL10,INSIG1,GRHL1,PMAIP1,ZNF697,GBP1,MFSD2A,RPS6KL1,SLC7A5,TNFSF15,HS3ST3B1,GEM,CMPK2 |
| 2.285e-02 | -3.78 | V$ISRE_01 | MSigDB lists | V$ISRE_01 | 235 | 33 | 17377 | 1707 |
SORBS1,GPR65,PLAG1,OTX1,TNFSF13B,IKZF2,HMCN1,EYA4,PCDH7,ATXN7L1,DNAH6,MET,SCN2A,FIGN,ZNF385A,BDNF,UNC5C,KCNIP3,MSX1,SLC25A28,BCL11A,TSKU,CXCL10,IKZF3,TIFA,KPNA3,MAP2,MAP2K6,GNB4,TNFSF15,PPARGC1A,TNFRSF17,MEF2C |
| 2.285e-02 | -3.78 | V$CEBP_Q2 | MSigDB lists | V$CEBP_Q2 | 218 | 31 | 17377 | 1707 |
PLA2G4A,CGN,BDNF,NEK10,RASAL2,TTC39B,COL4A3,COL4A4,PYGO1,CHAC1,COLEC10,TBC1D16,PLCB1,PFN2,NEO1,ID3,TCF7L1,MAP2K6,LHX6,PRKG1,MPPED2,TSC22D1,BEND4,ZBTB20,PROS1,PDE4D,TMEM132E,HOXB9,C15orf41,DDIT3,RNF152 |
| 2.285e-02 | -3.78 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_UP | 135 | 21 | 17377 | 1707 |
MN1,ANKRD13D,C1QTNF3,PFKFB2,BACE1,DCHS1,PRDM8,GPR180,SATB1,SIPA1L2,IGF1R,UNC13B,RALGPS2,CACNB2,TRIM3,NXPH4,MAOA,ADCY6,HOXB9,STON2,DENND5B |
| 2.285e-02 | -3.78 | MEL18_DN.V1_UP | MSigDB lists | MEL18_DN.V1_UP | 135 | 21 | 17377 | 1707 |
TYRO3,VEGFC,SLC6A9,C3orf52,VLDLR,KIF21B,ASPH,F3,DDIT4,MMP15,TGFBR3,SLC7A11,PMEPA1,CSF1,STC2,SLC2A6,SLC7A5,INHBE,STEAP3,SLC1A5,NRP1 |
| 2.285e-02 | -3.78 | AACATTC,MIR-409-3P | MSigDB lists | AACATTC,MIR-409-3P | 135 | 21 | 17377 | 1707 |
UST,BDNF,KCNIP3,ELOVL4,MSTN,YPEL2,EDEM3,SETBP1,KCTD12,CREB5,GRK6,CTNNA2,EYA4,TGFBR3,BACH2,SEMA4F,MAP1A,FRAS1,TOX,HS3ST3B1,MET |
| 2.287e-02 | -3.78 | TFAP2C (transcription factor AP-2 gamma) | protein interactions | 7022 | 17 | 5 | 17029 | 1718 |
CCNG1,KDM5B,MYC,KCTD1,TFAP2A |
| 2.287e-02 | -3.78 | KLHL21 (kelch like family member 21) | protein interactions | 9903 | 17 | 5 | 17029 | 1718 |
CHUK,RPL28,TPM1,KLHL29,KLHL13 |
| 2.287e-02 | -3.78 | NGB (neuroglobin) | protein interactions | 58157 | 17 | 5 | 17029 | 1718 |
TDO2,REL,GNAO1,MPP2,GNAI1 |
| 2.287e-02 | -3.78 | KCNJ12 (potassium voltage-gated channel subfamily J member 12) | protein interactions | 3768 | 17 | 5 | 17029 | 1718 |
LIN7A,DLG2,ABLIM1,APBA1,SNTB1 |
| 2.287e-02 | -3.78 | TMEM14B (transmembrane protein 14B) | protein interactions | 81853 | 17 | 5 | 17029 | 1718 |
SFXN1,MID2,PRTFDC1,KHDRBS2,SPRY2 |
| 2.287e-02 | -3.78 | BATF2 (basic leucine zipper ATF-like transcription factor 2) | protein interactions | 116071 | 17 | 5 | 17029 | 1718 |
C2orf88,CEBPA,DBP,ATF4,DDIT3 |
| 2.287e-02 | -3.78 | human chr12q13.3 | chromosome location | human chr12q13.3 | 56 | 9 | 26185 | 1967 |
NDUFA4L2,INHBC,KIF5A,INHBE,NXPH4,MARS,DDIT3,RBMS2,GLI1 |
| 2.289e-02 | -3.78 | Amino acid synthesis and interconversion (transamination) | REACTOME pathways | R-HSA-70614 | 31 | 7 | 10287 | 971 |
GPT2,SERINC5,ASNS,PHGDH,PSPH,SERINC2,PYCR1 |
| 2.290e-02 | -3.78 | GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 278 | 38 | 17377 | 1707 |
NEK10,AVPI1,ACSL1,FZD8,NTRK3,PKN1,TPD52L1,TLR3,GHR,DAB2IP,MARCKS,IQGAP3,TLR4,TNFRSF11A,HSPA2,SPRY2,SYK,RASGRP1,PDGFRB,PAK1,FZD4,TGFA,RAPGEF2,LRRK2,DUSP9,CD40,TLR6,FGFR1,SNCA,MAPKAPK2,MAP2K6,ERN1,DUSP19,DIRAS1,HGF,TNFSF15,MAPK10,ATP2B4 |
| 2.292e-02 | -3.78 | GO_MORPHOGENESIS_OF_AN_EPITHELIUM | MSigDB lists | GO_MORPHOGENESIS_OF_AN_EPITHELIUM | 392 | 51 | 17377 | 1707 |
EFNB2,ACVR1,CELSR1,LGR4,ST14,GATA3,OVOL2,DDR1,SKI,SETDB2,CA2,FLRT3,FRAS1,MYC,RAP2A,TFAP2A,LRP6,MET,SLIT2,SPRY2,PRKACB,NKX2-1,FZD1,EPB41L5,PAK1,VEGFC,INTU,MICAL2,KDM5B,KLHL3,DCHS1,PRICKLE1,YAP1,RYR2,WNT11,FGFR1,SMAD3,FAT4,PTK7,CSF1,SEMA3C,HOXD13,BMP4,NRP1,TMEFF2,SEMA3A,COBL,SIX2,FOXA1,BTRC,MEF2C |
| 2.293e-02 | -3.78 | TGFBR1 (transforming growth factor beta receptor 1) | protein interactions | 7046 | 196 | 29 | 17029 | 1718 |
PAK1,RAB3B,ACVR1,SKAP2,BMPR2,RHOD,RAB6B,NUAK2,RHPN2,CHUK,RAB38,ZFYVE9,PLEKHB1,SKI,SMAD3,CHN1,TTC1,CHN2,RASD2,RAP2A,TSC22D1,RNF130,PPP2R2B,ARL4D,NRP1,TPM1,SMAD6,MAP3K20,OCLN |
| 2.293e-02 | -3.78 | HDAC4 (histone deacetylase 4) | protein interactions | 9759 | 196 | 29 | 17029 | 1718 |
CGN,PRKN,PHLDB2,RUNX2,RASAL2,KDM5B,JDP2,GATA3,ATF3,CBY1,LPIN3,IKZF2,FAM110B,MECOM,AHRR,SMAD3,RANBP2,IKZF3,NAV1,ZNF354A,RALGPS2,BCL6,MAP3K21,OSBPL6,SYK,SFN,CEBPD,GAB2,MEF2C |
| 2.295e-02 | -3.77 | GO_PROTEIN_COMPLEX_BINDING | MSigDB lists | GO_PROTEIN_COMPLEX_BINDING | 885 | 105 | 17377 | 1707 |
ACVR1,SORBS1,ID1,FGF13,AKAP5,KIF5A,MYO1B,PKP2,ADD2,KIF21B,DDR1,SNX9,COL14A1,DOCK2,PPP1R9A,CTNNA2,SCIN,EPCAM,BAG3,TGFBR3,ABI3BP,REEP1,ACVR2A,JAKMIP2,DAB2IP,MARCKS,PROS1,PCOLCE2,SERPINH1,TLN2,JAKMIP3,GLI1,GAPDH,COL4A3,WISP3,ADM2,LRRK2,VIM,ACVR2B,ATP1B1,RAB38,JAM3,FGFR1,EML1,SNCA,GNAI1,SMAD3,IRS2,ENPP1,NCKAP1L,WIPF3,MAP2,CCBE1,PLK2,GNB4,ITGA2,GRB10,MID1,MYO1D,MRC2,FN1,LGALS3,ITGA6,APBB1,KIF5C,CHADL,EPHB1,APBA1,ADSSL1,MLC1,DYNC1I1,DOK5,MAP1A,IGF1R,EEF2,CACNB2,MYC,GAS2L3,SREBF1,MYO6,SYK,FES,DLGAP1,PAK1,DPYSL5,MID2,DISC1,LCA5,PXN,MYO10,SYBU,PLS1,SKAP1,MAP1B,FGR,FBN1,GNAO1,THBS4,CDH17,SVIL,KIF21A,CDH2,KIF1B,SMYD3,SIX2 |
| 2.297e-02 | -3.77 | myelin sheath | cellular component | GO:0043209 | 157 | 23 | 18223 | 1724 |
MYO1D,SERINC5,TUBA1A,ENO2,ASS1,ATP1B1,SNAP25,CANX,PHGDH,PLCB1,JAM3,CA13,TUBB4A,GSN,CA2,GNAO1,GNB4,EHD3,MPDZ,PACSIN1,STXBP1,HSPA2,CNTN1 |
| 2.297e-02 | -3.77 | neuron spine | cellular component | GO:0044309 | 157 | 23 | 18223 | 1724 |
GPM6A,DNM3,FARP1,SHANK2,APBB1,OPHN1,PRKAR2B,ARHGAP32,CANX,APBA1,PPP1R9A,NEDD4,BAIAP2,ARHGAP44,MAP1B,KCNN2,MPP2,RGS10,CTTN,CTTNBP2,APBA2,LZTS1,ATP2B1 |
| 2.298e-02 | -3.77 | GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 119 | 19 | 17377 | 1707 |
FER,SLC40A1,IGFBP6,RNF144A,HOMER2,FGF12,PHACTR2,PRKAR2B,TNS1,ZBBX,KCNC4,ENTPD1,FGR,ADAMTS3,MARCH3,MAPK13,DISP2,PTGES,TLL2 |
| 2.298e-02 | -3.77 | GO_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT | MSigDB lists | GO_EMBRYONIC_SKELETAL_SYSTEM_DEVELOPMENT | 119 | 19 | 17377 | 1707 |
RUNX2,NKX3-2,WNT11,SATB2,KIAA1217,HOXA1,SMAD3,WDR19,TFAP2A,PCGF2,ACVR2A,BMP4,DLX2,HOXB9,SHOX2,MMP16,SIX2,PCSK5,MEF2C |
| 2.298e-02 | -3.77 | V$CDPCR1_01 | MSigDB lists | V$CDPCR1_01 | 119 | 19 | 17377 | 1707 |
DPP10,MN1,IL15,FGF12,STAT5B,MGAT5B,IKZF2,NOVA1,FOXG1,PFN2,ATXN7L1,GRIK4,ZNF827,TMEM237,PCGF2,SERPINI1,ETV1,C15orf41,NR3C2 |
| 2.302e-02 | -3.77 | regulation of actin polymerization or depolymerization | biological process | GO:0008064 | 180 | 26 | 17256 | 1658 |
TENM1,FER,SSH3,EVL,TMSB15A,DSTN,EPS8,PREX1,ADD2,PFN2,RAC3,PPP1R9A,BAIAP2,SPIRE1,FHOD3,SCIN,GSN,PLEKHH2,MYADM,WIPF3,NCKAP1L,PRKCD,ARHGAP28,TMOD2,CTTN,SLIT2 |
| 2.305e-02 | -3.77 | paranodal junction assembly | biological process | GO:0030913 | 7 | 3 | 17256 | 1658 |
EPB41L3,UGT8,ANK2 |
| 2.305e-02 | -3.77 | kidney vasculature morphogenesis | biological process | GO:0061439 | 7 | 3 | 17256 | 1658 |
BMP4,NRP1,PDGFRB |
| 2.305e-02 | -3.77 | commitment of neuronal cell to specific neuron type in forebrain | biological process | GO:0021902 | 7 | 3 | 17256 | 1658 |
BCL11B,SATB2,GATA2 |
| 2.305e-02 | -3.77 | renal system vasculature morphogenesis | biological process | GO:0061438 | 7 | 3 | 17256 | 1658 |
BMP4,NRP1,PDGFRB |
| 2.305e-02 | -3.77 | tryptophan catabolic process to kynurenine | biological process | GO:0019441 | 7 | 3 | 17256 | 1658 |
AADAT,KMO,TDO2 |
| 2.305e-02 | -3.77 | cellular response to macrophage colony-stimulating factor stimulus | biological process | GO:0036006 | 7 | 3 | 17256 | 1658 |
FER,PDE1B,CSF1 |
| 2.305e-02 | -3.77 | AV node cell to bundle of His cell signaling | biological process | GO:0086027 | 7 | 3 | 17256 | 1658 |
TRPM4,SCN5A,CACNB2 |
| 2.305e-02 | -3.77 | branchiomotor neuron axon guidance | biological process | GO:0021785 | 7 | 3 | 17256 | 1658 |
NRP1,SEMA3A,PLXNA2 |
| 2.305e-02 | -3.77 | fatty acid elongation, polyunsaturated fatty acid | biological process | GO:0034626 | 7 | 3 | 17256 | 1658 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.305e-02 | -3.77 | taurine metabolic process | biological process | GO:0019530 | 7 | 3 | 17256 | 1658 |
STAT5B,PHGDH,GHR |
| 2.305e-02 | -3.77 | bud elongation involved in lung branching | biological process | GO:0060449 | 7 | 3 | 17256 | 1658 |
YAP1,BMP4,SPRY2 |
| 2.305e-02 | -3.77 | cellular triglyceride homeostasis | biological process | GO:0035356 | 7 | 3 | 17256 | 1658 |
C1QTNF3,XBP1,SLC25A27 |
| 2.305e-02 | -3.77 | modulation of inhibitory postsynaptic potential | biological process | GO:0098828 | 7 | 3 | 17256 | 1658 |
ABAT,UNC13B,RIMS2 |
| 2.305e-02 | -3.77 | AV node cell action potential | biological process | GO:0086016 | 7 | 3 | 17256 | 1658 |
TRPM4,SCN5A,CACNB2 |
| 2.305e-02 | -3.77 | alkanesulfonate metabolic process | biological process | GO:0019694 | 7 | 3 | 17256 | 1658 |
STAT5B,PHGDH,GHR |
| 2.305e-02 | -3.77 | fatty acid elongation, monounsaturated fatty acid | biological process | GO:0034625 | 7 | 3 | 17256 | 1658 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.305e-02 | -3.77 | response to macrophage colony-stimulating factor | biological process | GO:0036005 | 7 | 3 | 17256 | 1658 |
FER,PDE1B,CSF1 |
| 2.305e-02 | -3.77 | positive regulation of blood pressure by epinephrine-norepinephrine | biological process | GO:0003321 | 7 | 3 | 17256 | 1658 |
PDE4D,TPM1,ADRB1 |
| 2.305e-02 | -3.77 | regulation of mesodermal cell fate specification | biological process | GO:0042661 | 7 | 3 | 17256 | 1658 |
BMPR1A,FGFR1,DKK1 |
| 2.305e-02 | -3.77 | pharyngeal arch artery morphogenesis | biological process | GO:0061626 | 7 | 3 | 17256 | 1658 |
BMPR1A,BMP4,BMPR2 |
| 2.305e-02 | -3.77 | fatty acid elongation, saturated fatty acid | biological process | GO:0019367 | 7 | 3 | 17256 | 1658 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.305e-02 | -3.77 | regulation of atrial cardiac muscle cell action potential | biological process | GO:0098910 | 7 | 3 | 17256 | 1658 |
TRPM4,RYR2,ANK2 |
| 2.305e-02 | -3.77 | regulation of metanephric nephron tubule epithelial cell differentiation | biological process | GO:0072307 | 7 | 3 | 17256 | 1658 |
YAP1,FAT4,WWTR1 |
| 2.305e-02 | -3.77 | cardiac muscle cell-cardiac muscle cell adhesion | biological process | GO:0086042 | 7 | 3 | 17256 | 1658 |
PKP2,DSP,DSG2 |
| 2.305e-02 | -3.77 | regulation of peptidyl-cysteine S-nitrosylation | biological process | GO:2000169 | 7 | 3 | 17256 | 1658 |
ATP2B4,NOS1AP,NCOA7 |
| 2.305e-02 | -3.77 | anterior/posterior axon guidance | biological process | GO:0033564 | 7 | 3 | 17256 | 1658 |
UNC5C,UNC5B,DCC |
| 2.305e-02 | -3.77 | fatty acid elongation, unsaturated fatty acid | biological process | GO:0019368 | 7 | 3 | 17256 | 1658 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.305e-02 | -3.77 | histone-threonine phosphorylation | biological process | GO:0035405 | 7 | 3 | 17256 | 1658 |
PKN1,PRKCA,PRKCB |
| 2.305e-02 | -3.77 | positive regulation of inhibitory postsynaptic potential | biological process | GO:0097151 | 7 | 3 | 17256 | 1658 |
ABAT,UNC13B,RIMS2 |
| 2.308e-02 | -3.77 | regulation of oxidative stress-induced cell death | biological process | GO:1903201 | 74 | 13 | 17256 | 1658 |
GPR37,PRKN,ATF4,LRRK2,NCOA7,PDE8A,HGF,RACK1,MET,TLR6,TLR4,FZD1,PYCR1 |
| 2.309e-02 | -3.77 | ROSS_ACUTE_MYELOID_LEUKEMIA_CBF | MSigDB lists | ROSS_ACUTE_MYELOID_LEUKEMIA_CBF | 80 | 14 | 17377 | 1707 |
MN1,DEXI,PRAME,TMEM43,PMAIP1,CRIP2,HOMER2,DEPTOR,PSD3,EGFL7,GALNT14,ATP2B4,TPK1,ISG20 |
| 2.309e-02 | -3.77 | SMID_BREAST_CANCER_LUMINAL_A_UP | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_A_UP | 80 | 14 | 17377 | 1707 |
RTN1,HLF,C1orf21,STC2,CHRDL1,ATRNL1,PSD3,MAOA,COL14A1,LEPR,GFRA1,DUSP1,PCSK5,PNMA2 |
| 2.310e-02 | -3.77 | trabecula formation | biological process | GO:0060343 | 24 | 6 | 17256 | 1658 |
SLC40A1,OVOL2,TGFBR3,ADGRG6,HEY1,FHL2 |
| 2.310e-02 | -3.77 | regulation of activin receptor signaling pathway | biological process | GO:0032925 | 24 | 6 | 17256 | 1658 |
ACVR2A,ACVR2B,ACVR1,MAGI2,DACT1,SKI |
| 2.310e-02 | -3.77 | negative regulation of myoblast differentiation | biological process | GO:0045662 | 24 | 6 | 17256 | 1658 |
PRICKLE1,CXCL10,ID3,BMP4,MSTN,DDIT3 |
| 2.310e-02 | -3.77 | indole-containing compound metabolic process | biological process | GO:0042430 | 24 | 6 | 17256 | 1658 |
RNF180,BTBD9,PDE1B,AADAT,KMO,TDO2 |
| 2.310e-02 | -3.77 | positive regulation of protein oligomerization | biological process | GO:0032461 | 24 | 6 | 17256 | 1658 |
JCHAIN,HRK,RACK1,PMAIP1,SNX9,BIK |
| 2.310e-02 | -3.77 | regulation of establishment or maintenance of cell polarity | biological process | GO:0032878 | 24 | 6 | 17256 | 1658 |
GATA3,GSN,RACK1,RIPOR2,SHTN1,DOCK8 |
| 2.310e-02 | -3.77 | clathrin-dependent endocytosis | biological process | GO:0072583 | 24 | 6 | 17256 | 1658 |
HIP1,INPP5F,CANX,FCHO2,FNBP1L,DNAJC6 |
| 2.310e-02 | -3.77 | blood vessel endothelial cell migration | biological process | GO:0043534 | 24 | 6 | 17256 | 1658 |
EFNB2,ID1,NRP1,SLIT2,NR4A1,GPLD1 |
| 2.313e-02 | -3.77 | GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_AMINO_ACID_TRANSMEMBRANE_TRANSPORT | 65 | 12 | 17377 | 1707 |
SLC7A1,SLC6A9,SLC7A11,SLC36A1,SLC7A5,SLC36A4,SLC6A15,SLC7A2,SLC1A3,SLC1A5,SLC16A10,SLC43A1 |
| 2.313e-02 | -3.77 | GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION | 65 | 12 | 17377 | 1707 |
VEGFC,AMOTL1,BMPR2,CCBE1,ITGB3,GATA3,BMP4,MET,PRKCA,NRP1,FGFR1,GPLD1 |
| 2.315e-02 | -3.77 | C3AR1 (complement C3a receptor 1) | protein interactions | 719 | 93 | 16 | 17029 | 1718 |
TSPAN15,ATP9A,C4A,AGPAT4,SLC7A2,SLC19A2,TCAF2,EDA,MSMO1,SLC22A18,ZDHHC6,TMEM120B,CKAP4,ATP2B4,B4GALT7,TMEM56 |
| 2.315e-02 | -3.77 | FAM189A2 (family with sequence similarity 189 member A2) | protein interactions | 9413 | 78 | 14 | 17029 | 1718 |
CYP51A1,BAG3,ANKRD13D,CHRNA5,PDZD8,LGR4,KCNG1,ADGRL1,HECW2,SLC12A6,SFN,NEDD4,GJC1,HMGCR |
| 2.318e-02 | -3.76 | cellular amino acid metabolic process | biological process | GO:0006520 | 311 | 41 | 17256 | 1658 |
CARS,GPT2,NMNAT3,SERINC5,AASS,GCAT,RIMKLA,ASS1,CBS,STAT5B,SLC7A2,SLC1A3,ABAT,PHGDH,ADSSL1,AARS,ASNS,AADAT,KMO,ERO1B,GHR,PHYKPL,GATM,NOS3,GLDC,CTH,ATF4,GARS,HYKK,MARS,AMDHD1,WARS,PYCR1,DDAH1,RIMKLB,PLOD2,TDO2,PEMT,SLC7A5,P4HA1,PSPH |
| 2.321e-02 | -3.76 | Tetraspanin | interpro domains | IPR000301 | 30 | 7 | 18492 | 1811 |
TSPAN12,CD37,TSPAN13,TSPAN15,TSPAN9,TSPAN17,CD53 |
| 2.322e-02 | -3.76 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | 419 | 54 | 17377 | 1707 |
DMXL2,SEC24D,RECK,BLVRB,HERC5,KCTD12,GAS6,LACC1,HERC6,LCP2,SPIRE1,CYP51A1,CHN2,SETDB2,PIK3AP1,BCL6,SGK1,BNIP3,MARCKS,TLR4,GATM,ZFP36L2,LRP12,PRKACB,ATP2B1,CEBPD,GAB2,DUSP1,RIN2,ARAP2,WLS,MPP1,SLC39A8,ARID5B,SPATA13,MAFB,PRICKLE1,PDE8A,SLC46A3,ISG20,HEG1,TBC1D2,CD37,CXCL10,FCHO2,PRCP,GBP1,GNB4,C1orf21,NCOA7,KLF5,CMPK2,SLFN5,STOM |
| 2.323e-02 | -3.76 | plasma membrane raft | cellular component | GO:0044853 | 99 | 16 | 18223 | 1724 |
MYO1D,SCN5A,BMPR2,BVES,LRP4,LRRK2,ADD2,ATP1B1,LCP2,MLC1,NOS1AP,LRP6,BMPR1A,CDH2,ATP2B4,NOS3 |
| 2.325e-02 | -3.76 | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_DN | MSigDB lists | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_DN | 193 | 28 | 17377 | 1707 |
FAM171B,ENO2,SCAMP1,CRIM1,TES,JDP2,CYP4V2,ADAMTS6,PDE8A,SHISA2,ATF3,SAV1,PFN2,AARS,PPP2R3A,BATF3,MAPKAPK2,ENPP1,TMCO3,CDC14B,RASGRF2,XBP1,SGK3,TANC2,RCAN3,CKAP4,LRP12,GAB2 |
| 2.325e-02 | -3.76 | V$RP58_01 | MSigDB lists | V$RP58_01 | 193 | 28 | 17377 | 1707 |
CREB3L2,PTCH2,ACVR1,SORBS1,ANK2,ARHGAP22,PRICKLE1,TNS1,ATF3,GPSM2,TNKS1BP1,MBNL2,TSKU,FOXP2,NAV1,PTK7,CACNB2,PDE10A,ERN1,B3GALT2,NXPH4,GRIN2D,KLF5,HGF,KIF21A,SEPT3,SHOX2,RIMS2 |
| 2.325e-02 | -3.76 | GSE3039_CD4_TCELL_VS_B1_BCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_B1_BCELL_UP | 193 | 28 | 17377 | 1707 |
CREB3L2,FN1,SDC3,RASL11B,ITPR2,PALLD,NCS1,FGFR1,HTR7,RTN1,EPB41L3,GSN,GALNT1,MYADM,LRRC6,TACC2,KMO,CFHR1,FAM168A,C1orf21,CDH17,SMTN,UACA,CTTN,TANC2,STXBP1,ZNF385A,CYP1B1 |
| 2.325e-02 | -3.76 | GSE7831_CPG_VS_INFLUENZA_STIM_PDC_1H_DN | MSigDB lists | GSE7831_CPG_VS_INFLUENZA_STIM_PDC_1H_DN | 193 | 28 | 17377 | 1707 |
GNG12,GDAP1,FN1,LGALS3,SLK,SPATA6,DSTN,ELOVL3,LDLR,ASS1,KIF5C,IL13RA1,ABCC2,LHPP,INTS6,GSN,ENTPD7,AFF2,B3GALT2,TUFT1,SLCO5A1,HPGD,SH3BGRL2,RCAN3,SNX10,MED12L,ZNF385A,IGFBP3 |
| 2.326e-02 | -3.76 | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_UP | MSigDB lists | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_UP | 168 | 25 | 17377 | 1707 |
PLA2G4A,KLF8,GCNT2,TRIM2,PXN,SLC39A8,FOXN3,LITAF,LILRB1,RNF24,CBY1,BATF,NUDT12,KCNC4,SNX9,AHRR,IRS2,INSIG1,ENTPD7,ATP7B,CECR2,PRELID2,ADCY6,MDH1B,RBMS2 |
| 2.326e-02 | -3.76 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_DN | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_3H_DN | 168 | 25 | 17377 | 1707 |
NUDT10,SLC37A1,UROS,MSTN,HERC5,PDE8A,SCD,SLC36A4,SLC12A6,CDC42BPA,SLCO3A1,IL18R1,SLC19A2,NIPSNAP3B,CCNJ,TMEM53,MFSD2A,STARD4,OPN3,ACVR2A,FIG4,PCOLCE2,FAR2,TLR4,FMNL2 |
| 2.334e-02 | -3.76 | FA58C | smart domains | SM00231 | 21 | 6 | 9493 | 1056 |
CPXM2,NRP1,DDR1,CNTNAP3,DCBLD1,DCBLD2 |
| 2.339e-02 | -3.76 | regulation of protein serine/threonine kinase activity | biological process | GO:0071900 | 511 | 63 | 17256 | 1658 |
TENM1,TNIK,LATS2,NEK10,ACSL1,AVPI1,DUSP8,FZD8,IPO5,HERC5,CEBPA,NTRK3,PKN1,TPD52L1,STK24,TLR3,IGF1R,PRKCD,GHR,LRP6,INAVA,DAB2IP,IQGAP3,TLR4,TNFRSF11A,SYK,SPRY2,PDGFRB,RASGRP1,HMGCR,DUSP1,PAK1,SESN2,FZD4,PTPN6,TGFA,RAPGEF2,LRRK2,DUSP9,PRKAR2B,CCNG1,CD40,TLR6,FGFR1,SNCA,DKK1,MAPKAPK2,TRIB3,PTPRJ,MAP2K6,ERN1,MAP3K21,DUSP19,TNFSF15,HGF,DIRAS1,SPRY4,BMP4,MAPK10,MAP3K20,ATP2B4,SFN,PKIA |
| 2.341e-02 | -3.75 | postsynapse organization | biological process | GO:0099173 | 59 | 11 | 17256 | 1658 |
IGF1R,SHANK2,LRP4,NLGN4X,CTTN,NRXN1,EPHB1,ZNF365,CDH2,MAGI2,CTNND2 |
| 2.341e-02 | -3.75 | chordate embryonic development | biological process | GO:0043009 | 548 | 67 | 17256 | 1658 |
ACVR1,ST14,PLXNA2,GATA3,CEBPA,KIAA1217,SKI,EOMES,DACT1,TBC1D32,ACVR2A,PRKACB,FZD1,INTU,NKX3-2,SATB2,WNT11,RARRES2,FGFR1,SMAD3,PTK7,SEMA3C,BMPR1A,DLX2,TPM1,TANC2,VASH2,APBA2,HOXB9,COBL,PCSK5,HEY1,MEF2C,RUNX2,BMPR2,CELSR1,SEC24D,OVOL2,APBA1,PHGDH,HOPX,IRX5,MGAT1,GATA2,TFAP2A,LRP6,YBX3,NOS3,B9D1,EPB41L5,MSX1,DCHS1,PRICKLE1,PRDM1,ZFPM2,HOXA1,DKK1,HEG1,CEBPB,CECR2,WDR19,PCGF2,BMP4,SHOX2,MMP16,SIX2,FOXA1 |
| 2.343e-02 | -3.75 | RAPGEF6 (Rap guanine nucleotide exchange factor 6) | protein interactions | 51735 | 23 | 6 | 17029 | 1718 |
YAP1,WWC1,ENO1,PTPN13,RAP2A,NEDD4 |
| 2.343e-02 | -3.75 | ATP2A1 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1) | protein interactions | 487 | 23 | 6 | 17029 | 1718 |
IRS2,VNN2,GCNT2,ATOH1,LGR4,LRRCC1 |
| 2.343e-02 | -3.75 | MEGF10 (multiple EGF like domains 10) | protein interactions | 84466 | 23 | 6 | 17029 | 1718 |
CADPS2,GRB10,ARHGAP32,SYK,MCF2L2,SHTN1 |
| 2.343e-02 | -3.75 | SHANK2 (SH3 and multiple ankyrin repeat domains 2) | protein interactions | 22941 | 23 | 6 | 17029 | 1718 |
DLGAP1,CTTN,ADGRL2,ADGRB2,BAIAP2,ADGRL1 |
| 2.345e-02 | -3.75 | - | gene3d domains | 3.90.1150.10 | 34 | 8 | 8148 | 867 |
GPT2,MOCOS,GCAT,PHYKPL,ABAT,ETNPPL,CTH,GLDC |
| 2.345e-02 | -3.75 | IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN | MSigDB lists | IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN | 322 | 43 | 17377 | 1707 |
EFNB2,SV2B,PTPRD,SELL,GALNT13,CHSY1,ITPR2,SPATS2L,SATB1,GAS1,SCARF2,MAP7,TSPAN13,MPDZ,MARCKS,IQGAP3,PLTP,MYT1,MEIS2,FZD4,CYTH3,HIP1,CALCRL,ST6GALNAC3,PRDM1,AMIGO1,TTC28,ATP10D,CTIF,PTPRC,EBF1,GSN,PDLIM3,MAP2,PLOD2,GNB4,PLXDC2,ADRB1,HS3ST3B1,HK1,TPM1,SUSD4,STON2 |
| 2.347e-02 | -3.75 | membrane region | cellular component | GO:0098589 | 316 | 41 | 18223 | 1724 |
MYO1D,SCN5A,SORBS1,BMPR2,GLIPR1L1,BVES,BACE1,CMTM8,LRP4,ADD2,EPHB1,LCP2,MLC1,NOS1AP,EEF2,LRP6,GRIP1,SERPINH1,ATP2B1,NOS3,CD55,RHOQ,TUBA1A,ANK2,LRRK2,ADCY1,PRKAR2B,ATP1B1,TLR6,GNAI1,PTPRC,RANBP2,MYADM,HPSE,TNFRSF1A,BMPR1A,UNC5B,CDH2,ATP2B4,CNTN1,STOM |
| 2.348e-02 | -3.75 | MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED | 491 | 62 | 17377 | 1707 |
PHACTR3,TFCP2L1,MOCOS,PLSCR4,LGALS3,IGFBP6,ST14,LPCAT2,GALNT6,HEBP1,CYP4V2,ASS1,LAMC3,NDRG2,RASD1,ISYNA1,ADSSL1,SCIN,TUBB4A,MCOLN2,SYCP2,SPEG,SEMA4F,BHLHA15,MARVELD2,DSG2,SCARF2,SGK3,SLC2A12,AFAP1L2,LOXL4,TMEM37,CLVS2,NIPAL2,FAR2,MOXD1,DLGAP1,FGFR4,GPR176,RAX,SSH3,GCA,RAB3B,SLC39A8,SYBU,DUSP9,TTC22,FGF17,NAP1L5,GSN,GYPC,L3MBTL4,RASGRF2,HEYL,THBS4,KCNG1,THSD7B,FBRSL1,GRB10,MAPK13,OXTR,CHMP4C |
| 2.352e-02 | -3.75 | TMFOUR | prints domains | PR00259 | 30 | 7 | 4652 | 458 |
TSPAN12,CD37,TSPAN13,TSPAN15,TSPAN9,TSPAN17,CD53 |
| 2.352e-02 | -3.75 | V$RORA1_01 | MSigDB lists | V$RORA1_01 | 227 | 32 | 17377 | 1707 |
PCDH18,KIF5A,FHDC1,SLC25A27,GTF2IRD1,NDRG2,ABAT,SATB1,NEO1,NELL2,NAV1,DACT1,CACNB2,CHRDL1,JAKMIP2,PACSIN1,GPR161,CTH,GLI1,LCA5,EFNA3,STRADB,ASPH,KHDRBS2,GABARAPL1,ATPAF2,ERN1,B3GALT2,MCC,DBP,NRP1,MEF2C |
| 2.355e-02 | -3.75 | TNFR_NGFR_2 | prosite domains | PS50050 | 22 | 6 | 12060 | 1278 |
TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A |
| 2.355e-02 | -3.75 | GST_NTER | prosite domains | PS50404 | 22 | 6 | 12060 | 1278 |
GSTM3,GSTO1,GDAP1,GSTM2,GSTO2,GSTM4 |
| 2.355e-02 | -3.75 | activin binding | molecular function | GO:0048185 | 12 | 4 | 17224 | 1680 |
ACVR2A,ACVR2B,ACVR1,TGFBR3 |
| 2.355e-02 | -3.75 | diacylglycerol binding | molecular function | GO:0019992 | 12 | 4 | 17224 | 1680 |
UNC13B,PLTP,RAPGEF2,RASGRP1 |
| 2.355e-02 | -3.75 | carbon-sulfur lyase activity | molecular function | GO:0016846 | 12 | 4 | 17224 | 1680 |
ALOX5AP,MGST3,CENPV,CTH |
| 2.355e-02 | -3.75 | oligopeptide binding | molecular function | GO:1900750 | 12 | 4 | 17224 | 1680 |
GSTM3,GSTM2,PTGES,GSTM4 |
| 2.355e-02 | -3.75 | serine-type carboxypeptidase activity | molecular function | GO:0004185 | 12 | 4 | 17224 | 1680 |
CPXM2,CPVL,CPE,PRCP |
| 2.355e-02 | -3.75 | GO_ADIPOSE_TISSUE_DEVELOPMENT | MSigDB lists | GO_ADIPOSE_TISSUE_DEVELOPMENT | 30 | 7 | 17377 | 1707 |
DYRK1B,SH3PXD2B,ZNF516,PPARGC1A,CSF1,XBP1,ARID5B |
| 2.355e-02 | -3.75 | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_UP | MSigDB lists | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_UP | 30 | 7 | 17377 | 1707 |
SGK1,SLC39A14,CA2,FRK,SLC39A8,SLK,ZNF629 |
| 2.355e-02 | -3.75 | SIMBULAN_PARP1_TARGETS_UP | MSigDB lists | SIMBULAN_PARP1_TARGETS_UP | 30 | 7 | 17377 | 1707 |
AK1,COL4A5,CCNG1,CTTN,ID1,EEF2,IGFBP6 |
| 2.355e-02 | -3.75 | BIOCARTA_NO1_PATHWAY | MSigDB lists | BIOCARTA_NO1_PATHWAY | 30 | 7 | 17377 | 1707 |
RYR2,PRKG2,SLC7A1,PRKAR2B,PRKACB,NOS3,PRKG1 |
| 2.355e-02 | -3.75 | GO_WW_DOMAIN_BINDING | MSigDB lists | GO_WW_DOMAIN_BINDING | 30 | 7 | 17377 | 1707 |
TCEAL3,ENAH,TNK2,NDFIP2,PMEPA1,RAPGEF2,LITAF |
| 2.355e-02 | -3.75 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_UP | 30 | 7 | 17377 | 1707 |
SGK1,VEGFC,PRAME,BCHE,ABI3BP,VAMP8,DUSP1 |
| 2.355e-02 | -3.75 | chr4q25 | MSigDB lists | chr4q25 | 30 | 7 | 17377 | 1707 |
TIFA,CYP2U1,PRSS12,NEUROG2,COL25A1,ANK2,RPL34 |
| 2.366e-02 | -3.74 | central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I | 12 | 4 | 17385 | 1698 |
RNF130,NACC2,KIAA1549,GNAI1 |
| 2.367e-02 | -3.74 | GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN | 160 | 24 | 17377 | 1707 |
RGS16,PTPN13,IPO5,MCOLN3,PPFIBP2,GATA3,COBLL1,NEDD4,MCU,ENTPD1,ANKRD42,AK1,FGR,ZBTB38,SOAT2,MGAT1,APLF,PLXDC2,RASD2,SQLE,DAB2IP,NRP1,MYO6,ALG10B |
| 2.367e-02 | -3.74 | GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_DN | MSigDB lists | GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_DN | 160 | 24 | 17377 | 1707 |
GCA,SLC3A2,GSTM2,STAT4,PHACTR2,IL13RA1,PLS1,IKZF2,PFN2,WARS,MCU,ENTPD1,ALDOC,GPR160,QPCTL,RAB31,TOX,TMED9,SLC22A15,BMPR1A,SNX10,FAM78B,PRKACB,PKIA |
| 2.367e-02 | -3.74 | MH1 | pfam domains | PF03165 | 12 | 4 | 17054 | 1666 |
SMAD3,SMAD9,SMAD6,NFIA |
| 2.367e-02 | -3.74 | Gla | pfam domains | PF00594 | 12 | 4 | 17054 | 1666 |
PRRG1,PROS1,GAS6,PRRG4 |
| 2.371e-02 | -3.74 | cation binding | molecular function | GO:0043169 | 4185 | 442 | 17224 | 1680 |
DOC2A,MYCBP2,ADAL,ACVR1,PDE1B,ATP8A1,LDLR,GATA3,ADAMTS6,PRKCA,CA8,AARS,EYA4,NCS1,STK24,PCDH7,TRPS1,SKI,EPDR1,MOK,IKZF5,ZFYVE28,RAP2A,SP140,CPE,PLTP,GLDC,SMAD9,ACVR1C,NR6A1,MSRB3,EFHC1,KCND3,ACVR2B,F12,CA13,GNAI1,ENPP1,ZNF266,SH3RF1,CCBE1,ENTPD7,ATP7B,BMP1,ZBTB20,ERCC5,NRP1,SPOCK3,LPP,CARS,LATS2,KLF8,CELSR1,ZHX3,CYP2J2,ITGA6,ZNF25,SLC1A3,ADSSL1,HPCAL4,CHD5,PRRG4,MECOM,CHN1,ABLIM1,GBGT1,MSMO1,APLF,ZIC5,CPXM2,LMAN2,CADPS2,LOXL4,MOXD1,ZNF518B,MAST4,GLIS1,CHRM3,RIMS2,ZNF385A,RNF152,TBC1D8B,VLDLR,DCHS1,EFHC2,ZNF605,FHL2,RYR2,NSD2,PLS1,C1R,ZBBX,CDC42BPA,PLCB1,MBNL2,ZNF558,CPEB1,MMP15,DAGLA,RIMKLB,ADAMTS3,THBS4,QPCTL,MATN2,CDH17,CDH2,SMYD3,AMPD1,CSRP2,ACSM3,PLA2G4A,NUDT10,ZNF516,RNF144A,GALNT12,GALNT6,ZNF311,NRXN1,DDR1,NUDT12,ZFYVE9,RNF150,ZNF827,NELL2,CHRNA5,ZNF438,PDE4D,PJA1,ZNF365,MYT1,DZANK1,NECAB1,RNF145,ADCY1,PRKCQ,ATP1B1,PYGO1,ASPH,ATP10D,ZNF618,METAP1D,ISG20,SNCA,ZNF396,ZNF711,HTR7,IKZF3,PDLIM3,PRKCB,BEX3,TDO2,ZNF697,ZNF704,PAM,RCN3,P4HA1,KLF5,BMPR1A,NR3C2,MID1,PLSCR4,ATP9A,PLAG1,CBS,GAS6,CREB5,ZNF219,INPP1,COL27A1,KDM7A,MGAT1,NPTXR,TBC1D9,GFI1,SMAD6,ZFP36L2,SMPDL3A,B4GALT6,TRPM4,PDLIM7,VAV3,PXN,ARAP2,ARHGEF28,CLYBL,CACNA1E,RAPGEF2,RASA3,ATP11A,ZNF714,ZIC1,HEG1,GALNT3,ZFP62,NSD1,PCDHB7,PLOD2,TERT,GNAO1,PCGF2,PGM2L1,NEK11,LRRK1,B4GALT7,ATP2B4,TPT1,NUDT17,PHC1,ATP1A3,TLL2,TRIM2,TRIM16,SYT12,LMCD1,JCHAIN,ITPR2,MGAT5B,ABAT,SYT14,IKZF2,DNER,HMCN1,FSTL5,PLS3,CYP51A1,TUBB4A,ADPRHL1,FKBP9,RUFY4,PPM1E,RPS6KA2,MPPED2,MYRIP,GALNT18,ENO1,SLIT2,PRKACB,RASGRP1,ZNF391,CYP1B1,ITGB7,TNK2,KCNIP3,MARK1,SESN2,CEMIP2,ATOX1,GDPD1,ZNF565,RNF44,SESN1,NT5DC2,EML1,TRIM9,GSN,KLF12,P4HA2,ERN1,TC2N,BCL11B,PRKAA2,LONRF1,MOCOS,ZNF395,SEC24D,ZCCHC24,RIMKLA,YPEL2,CYP4V2,ZNF215,ZIC2,GALNT13,SCD,CHSY1,PCDHB14,RNF141,EFEMP1,RNF180,GALNT1,ZBTB38,PRTFDC1,CA2,ZNF354A,BCHE,ZNF440,GATA2,FRAS1,PDE10A,EBF4,ADCY6,LIMCH1,RNF148,NOS3,ZNF629,CHSY3,PCDH10,CDH26,MID2,HBG2,RNF170,MGAT4B,TCEA3,EDEM3,OBSCN,PDE8A,GALNT17,PRDM1,LHPP,STEAP1,AMDHD1,PLAGL1,FAT1,EGFL7,RNF122,TESC,MME,PRKN,ZSWIM5,NEK10,CELSR3,LPCAT2,MORC4,COL18A1,ZNF83,RNF24,BCL6B,LACC1,CANX,PCLO,CYP26A1,SP8,ZSCAN5A,SCIN,RIDA,ZNF362,IDI1,UNC13B,SETDB2,PDZD8,LHX6,BCL6,ZNF521,ACVR2A,STEAP3,PROS1,ZNF488,ZNF460,SP140L,SNAI2,GLI1,IGFBP3,GCA,ANTXR2,CSN2,PRDM13,TES,ACO1,RNF125,CHRNA6,EFCC1,ZNF569,BCL11A,SMAD3,RANBP2,ZNF93,LMLN,TRIM34,RNF217,ITGA2,FAAP20,RNF130,CYP2U1,ZNF701,PSPH,MAST1,MAN2B2,PCDH18,DYRK3,NECAB2,ENO2,BMPR2,CLGN,LRP4,MCTP2,CLSTN2,SELL,PRDM8,HBE1,SLX1B,OVOL2,PPP2R3A,FOXP2,CHN2,GTSF1,PRKCD,EHD3,DSG2,TRIM3,MARCH3,PRICKLE2,KLF9,PCK2,TNFRSF11A,FKBP14,ATP2B1,MOB1B,MICAL2,USP2,KDM5B,HNF4G,ESRRG,NR4A1,CRIP2,LITAF,ASAP3,NUAK2,OGDHL,PRICKLE1,PRRG1,AGAP2,ZFPM2,EXOG,GALNT14,MGMT,SMPDL3B,RERE,EBF1,ADAMTS17,DDAH1,FAT4,L3MBTL4,FBN1,ZNF214,ZNF474,ZNF808,GEM,THAP10,RNF157,MAP3K20,MMP16,CACNA2D1,ZNF235 |
| 2.373e-02 | -3.74 | regulation of cellular response to growth factor stimulus | biological process | GO:0090287 | 276 | 37 | 17256 | 1658 |
NBL1,RUNX2,BMPR2,RASL11B,GATA3,DOK5,NEDD4,SKI,NEO1,TGFBR3,ITGB3,CHRDL1,ACVR2A,DAB2IP,SMAD6,SLIT2,SPRY2,PCSK6,FZD1,NKX2-1,VEGFC,MSX1,FZD4,SHISA2,FGFR1,DKK1,SMAD3,FBN1,PMEPA1,ADAMTS3,PRKCB,CCBE1,RBPMS2,GRB10,BMP4,SPRY4,SPART |
| 2.373e-02 | -3.74 | determination of bilateral symmetry | biological process | GO:0009855 | 122 | 19 | 17256 | 1658 |
MICAL2,NBL1,ACVR1,NKX3-2,OVOL2,ACVR2B,SMAD3,ARMC4,SETDB2,LRRC6,DYNC2LI1,TBC1D32,ACVR2A,DYNC2H1,DISP1,DNAH5,MEF2C,PCSK5,PCSK6 |
| 2.373e-02 | -3.74 | actin filament bundle | cellular component | GO:0032432 | 60 | 11 | 18223 | 1724 |
PDLIM7,ABLIM1,SYNPO2,SORBS1,PXN,FERMT2,PLS1,MARCKS,ROR1,TPM1,PLS3 |
| 2.374e-02 | -3.74 | regulation of insulin secretion | biological process | GO:0050796 | 172 | 25 | 17256 | 1658 |
TRPM4,PRKN,STXBP5L,ACVR1C,PFKFB2,CACNA1E,RAPGEF4,SYBU,ARL2,ITPR2,SNAP25,ABAT,PRKCA,NRXN1,MCU,GPLD1,NKX6-1,IRS2,ICA1,SREBF1,KCNS3,MARCKS,PCK2,MYRIP,HMGCR |
| 2.374e-02 | -3.74 | glucose homeostasis | biological process | GO:0042593 | 172 | 25 | 17256 | 1658 |
PRKAA2,FGFR4,SESN2,STXBP5L,CEBPA,GAS6,RACK1,LEPR,MCU,IRS2,RAB11FIP5,UNC13B,IGF1R,ERO1B,PRCP,BHLHA15,WFS1,ERN1,XBP1,HK2,PTPRN2,HK1,PCK2,PPARGC1A,FOXA1 |
| 2.374e-02 | -3.74 | carbohydrate homeostasis | biological process | GO:0033500 | 172 | 25 | 17256 | 1658 |
PRKAA2,FGFR4,SESN2,STXBP5L,CEBPA,GAS6,RACK1,LEPR,MCU,IRS2,RAB11FIP5,UNC13B,IGF1R,ERO1B,PRCP,BHLHA15,WFS1,ERN1,XBP1,HK2,PTPRN2,HK1,PCK2,PPARGC1A,FOXA1 |
| 2.380e-02 | -3.74 | GSE40273_EOS_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_EOS_KO_VS_WT_TREG_DN | 185 | 27 | 17377 | 1707 |
CELSR1,TUBA1A,PNP,ITPRIP,JDP2,ATP8A1,BLVRB,MCTP2,NUAK2,LRRCC1,ABHD6,ATXN7L1,OTUD1,GSN,PTPRJ,IKZF3,BACH2,HPSE,PRKCB,CECR2,MARVELD2,MAP7,SH3BGRL2,INPP5F,BMPR1A,RNF157,STXBP1 |
| 2.380e-02 | -3.74 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_UP | 185 | 27 | 17377 | 1707 |
EML6,ELOVL7,SPATA13,FHL2,RASL11B,PHACTR2,PRDM1,DOCK5,SMPDL3B,BAIAP2,NEDD4,ENTPD1,MSC,MYADM,SEMA4F,GAS2L3,C1orf21,RAP2A,ADRB1,SMTN,HRK,FIG4,FBXL2,DHCR7,NEB,NUDT17,STOM |
| 2.380e-02 | -3.74 | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_DN | MSigDB lists | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_DN | 185 | 27 | 17377 | 1707 |
RUNX2,LITAF,ATP1B1,NPC2,GRK6,NHP2,ZDHHC14,ADSSL1,SNX9,AARS,DDIT4,TXNDC5,MCOLN2,MAPKAPK2,RPL12,ASNS,CA2,EEPD1,TSC22D1,MAOA,SERPINH1,PACSIN1,PLTP,ETV1,PSPH,FES,HMGCR |
| 2.380e-02 | -3.74 | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | 185 | 27 | 17377 | 1707 |
MXI1,TTC39B,ENO2,LGALS3,GTF2IRD1,MEF2B,CHUK,STAT5B,OVOL2,FNDC3A,MFSD6,SLCO3A1,TBC1D19,IRS2,IFT81,SUGT1,EPB41L3,FBXO32,PMEPA1,FUT9,RPS11,FABP6,CDH17,SGK1,RNF130,MET,ABCG1 |
| 2.380e-02 | -3.74 | GSE9037_WT_VS_IRAK4_KO_BMDM_UP | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_BMDM_UP | 185 | 27 | 17377 | 1707 |
DOC2A,GPR176,SYNPO2,EIF4E3,PNRC1,FHL2,MSRB3,VIM,TMEM47,SAV1,PRKCA,PFN2,GAS1,FAT4,ZNF438,TERT,AKAP7,WFS1,CSF1,ABI3,LAMB1,NBEA,CCDC122,TTC39A,SNX10,ZNF385A,B4GALT6 |
| 2.380e-02 | -3.74 | GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_DN | MSigDB lists | GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_DN | 185 | 27 | 17377 | 1707 |
RGS16,PNP,SMAD9,SYT12,RUSC2,MYO1B,EFNA3,SELL,COL4A5,LRRC49,TTC22,RARRES2,NRXN1,STEAP1,RTN1,BNIP1,MAP1A,IGF1R,INSIG1,ABI3BP,RAB26,MPDZ,MAPK13,FIG4,TPM1,SUSD4,DDIT3 |
| 2.380e-02 | -3.74 | GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_DN | 185 | 27 | 17377 | 1707 |
TNIK,MSX1,CFH,IL15,ARID5B,AK4,SLC25A28,ATF3,CD40,PCLO,ATP10D,GAS1,WARS,MECOM,HEG1,BATF3,ISG20,CEBPB,CXCL10,RPS6KA2,INSIG1,GBP1,TRIM3,HK1,LIFR,CAND2,IGFBP3 |
| 2.380e-02 | -3.74 | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN | 185 | 27 | 17377 | 1707 |
BCL11B,ACSL1,SLK,FOXN3,ARID5B,LRRK2,MCOLN3,SLC25A27,SPATA13,CALCRL,RNF125,SCD,KIF21B,TLR6,ATP10D,SKI,RNF141,NSD1,RALGPS2,MARCH3,INPP5F,SEPT3,VGLL4,SYK,RASGRP1,ATP2B1,SMPDL3A |
| 2.380e-02 | -3.74 | GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_DN | MSigDB lists | GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_DN | 185 | 27 | 17377 | 1707 |
PTCH2,BDNF,PCDH10,ZHX3,ARHGEF11,MYO10,ESRP1,C3orf52,KIAA1324L,MSR1,ATF3,RABAC1,NPC2,CA8,PIBF1,STEAP1,PCDHB14,CAMK2N1,SYCP2,ATP7B,ADCY6,NTNG1,OSBPL6,KCTD1,CHMP4C,NKX2-1,HRASLS |
| 2.380e-02 | -3.74 | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_UP | MSigDB lists | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_UP | 185 | 27 | 17377 | 1707 |
MTG1,EPB41L5,STOX2,MVK,AKAP5,DNAJC6,DHCR24,MCOLN3,TMTC4,SELL,RYR2,WWC1,GABRR2,KIAA1217,MAGI3,SLC39A14,ZNF827,ID3,RPL12,MYC,ACER2,MCF2L,C1orf53,CCDC146,SPRED3,SLCO4C1,CDH2 |
| 2.380e-02 | -3.74 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | 185 | 27 | 17377 | 1707 |
ATL1,PCDH18,SH3BP2,ACSL1,ALOX5AP,RHOBTB1,ST14,PTPN6,CAPN5,LITAF,STRADB,SNX9,ENPP1,MYADM,PIK3AP1,ABCA5,AKAP7,CCDC122,CNNM2,ZBTB20,INPP5F,PCK2,TBC1D9,ZNF518B,HSPA2,DCBLD1,CTH |
| 2.380e-02 | -3.74 | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | 185 | 27 | 17377 | 1707 |
RIN2,MRC2,LGALS3,FN1,GABRB2,PRDM13,ZCCHC24,ACO1,NDRG2,TNS1,ATF3,IL13RA1,ABHD6,SEMA6A,FAM162A,CPEB1,KMO,PRCP,CSF1,CLMN,LRRK1,PCK2,NRP1,STXBP1,SMAD6,FES,TBC1D8 |
| 2.380e-02 | -3.74 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | 185 | 27 | 17377 | 1707 |
AMOTL1,TES,GPR65,MCTP2,RNF125,COL4A5,ATP1B1,NDFIP2,NUDT12,NAV1,CA2,SLC7A11,NCAM2,GPR155,RAP2A,SLC2A6,C1orf21,TNFRSF1A,KIAA0513,ERRFI1,ESD,CTTNBP2,TNFRSF11A,TESC,LRP12,RNF152,STOM |
| 2.384e-02 | -3.74 | meninges-meningioma | COSMIC cancer mutations | meninges-meningioma | 333 | 44 | 17385 | 1698 |
TFCP2L1,CGN,SLC6A9,C1QTNF3,EDA2R,CFH,ITPRIP,PLAG1,MYO1B,CTBP2,NTRK3,ITPR2,HECTD2,FOXP2,COL22A1,RPS6KA2,SLC7A11,EEF2,TACC2,DLX6,KAZN,DAB2IP,MET,RIMS2,CYP1B1,PTCH2,SLC36A1,MYO10,RAPGEF4,CYTH3,NFIA,GRID1,OBSCN,CR2,TTC30A,AGAP2,PAGE5,CRYBG3,FGFR1,TERT,PTK7,ATP7B,MYOM2,DISP1 |
| 2.385e-02 | -3.74 | AGCTCCT,MIR-28 | MSigDB lists | AGCTCCT,MIR-28 | 88 | 15 | 17377 | 1707 |
SMAD3,GPM6A,CRIM1,KIAA0355,CSF1,FOXN3,NDRG2,AMIGO1,TLN2,IQSEC2,EPHB1,HOXA1,SP140L,ZNF569,TRPS1 |
| 2.387e-02 | -3.74 | COS_domain | interpro domains | IPR017903 | 12 | 4 | 18492 | 1811 |
FSD1,TRIM9,MID2,MID1 |
| 2.387e-02 | -3.74 | L27_dom_sf | interpro domains | IPR036892 | 12 | 4 | 18492 | 1811 |
LIN7A,MPDZ,MPP7,MPP2 |
| 2.387e-02 | -3.74 | L27_dom | interpro domains | IPR004172 | 12 | 4 | 18492 | 1811 |
LIN7A,MPDZ,MPP7,MPP2 |
| 2.387e-02 | -3.74 | MAD_homology1_Dwarfin-type | interpro domains | IPR003619 | 12 | 4 | 18492 | 1811 |
SMAD3,SMAD9,SMAD6,NFIA |
| 2.389e-02 | -3.73 | calcium channel regulator activity | molecular function | GO:0005246 | 37 | 8 | 17224 | 1680 |
SGK1,TSPAN13,SGK2,NRXN1,HPCAL4,SGK3,PACSIN3,PRKG1 |
| 2.395e-02 | -3.73 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP | 340 | 45 | 17377 | 1707 |
ZNF516,FN1,TSPAN15,DOCK1,GCAT,GALNT6,STXBP6,ESRP1,MYO1B,MCOLN3,ARL2,COL18A1,KCTD12,FAM13A,DDR1,NEDD4,NEO1,STC2,OPN3,ENO1,BCL7A,COL6A2,GSTM2,CSN2,RNF170,MPP1,ATF3,ARHGAP32,ACVR2B,ATP1B1,CD40,TAF4B,SNTB1,HOMER3,DKK1,RPL28,NCAM2,ADAMTS3,EIF4EBP1,PCGF2,HGF,PSPH,SFN,LARP1,HEY1 |
| 2.395e-02 | -3.73 | AMOT (angiomotin) | protein interactions | 154796 | 101 | 17 | 17029 | 1718 |
PRKAA2,PRKN,LATS2,AMOTL1,PTPN21,YAP1,WWC1,HECW2,SAV1,NEDD4,PATJ,RASSF8,BAG3,MPP7,WWTR1,LIN7A,MPDZ |
| 2.395e-02 | -3.73 | CACNA1A (calcium voltage-gated channel subunit alpha1 A) | protein interactions | 773 | 101 | 17 | 17029 | 1718 |
TCTN2,KDM5B,CRIM1,ARHGAP22,CACNB4,MAP1B,EFEMP1,NELL2,LAMB1,MATN2,ALDOA,BCL6,TSC22D1,NDUFB8,ADGRL1,PCSK5,PCSK6 |
| 2.395e-02 | -3.73 | TGFBR2 (transforming growth factor beta receptor 2) | protein interactions | 7048 | 101 | 17 | 17029 | 1718 |
PAK1,ACVR1,RAB6B,ACVR2B,FGFR1,ZFYVE9,SMAD3,TGFBR3,MYADM,TERT,PKN3,TSC22D1,PTPRS,ACVR2A,BMPR1A,NRP1,OCLN |
| 2.395e-02 | -3.73 | SLC39A4 (solute carrier family 39 member 4) | protein interactions | 55630 | 101 | 17 | 17029 | 1718 |
ELOVL4,TMEM43,SLC27A2,ATP9A,AGPAT4,SLITRK5,CHSY1,EDA,MGAT1,SLC22A18,TMEM143,ADCY6,STEAP3,FAR2,TMEM120B,CKAP4,ATP2B4 |
| 2.400e-02 | -3.73 | NADH pyrophosphatase activity | molecular function | GO:0035529 | 7 | 3 | 17224 | 1680 |
ENPP1,NUDT12,NUDT17 |
| 2.400e-02 | -3.73 | histone threonine kinase activity | molecular function | GO:0035184 | 7 | 3 | 17224 | 1680 |
PRKCA,PKN1,PRKCB |
| 2.400e-02 | -3.73 | fatty acid elongase activity | molecular function | GO:0009922 | 7 | 3 | 17224 | 1680 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.400e-02 | -3.73 | 3-oxo-cerotoyl-CoA synthase activity | molecular function | GO:0102337 | 7 | 3 | 17224 | 1680 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.400e-02 | -3.73 | amidine-lyase activity | molecular function | GO:0016842 | 7 | 3 | 17224 | 1680 |
CHAC1,GGACT,PAM |
| 2.400e-02 | -3.73 | 3-oxo-lignoceronyl-CoA synthase activity | molecular function | GO:0102338 | 7 | 3 | 17224 | 1680 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.400e-02 | -3.73 | very-long-chain 3-ketoacyl-CoA synthase activity | molecular function | GO:0102756 | 7 | 3 | 17224 | 1680 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.400e-02 | -3.73 | 3-oxo-arachidoyl-CoA synthase activity | molecular function | GO:0102336 | 7 | 3 | 17224 | 1680 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.403e-02 | -3.73 | cGMP-PKG signaling pathway | KEGG pathways | ko04022 | 163 | 25 | 7161 | 730 |
CREB3L2,ATF4,MYLK3,ADCY1,GTF2IRD1,MEF2B,CREB5,ATP1B1,ITPR2,GUCY1A2,PLCB1,GNAI1,IRS2,KCNMB4,AKT3,ADRB1,KCNMB3,PRKG1,PRKG2,ADCY6,ATP2B4,ATP2B1,NOS3,ATP1A3,MEF2C |
| 2.403e-02 | -3.73 | cGMP-PKG signaling pathway | KEGG pathways | hsa04022 | 163 | 25 | 7161 | 730 |
CREB3L2,ATF4,MYLK3,ADCY1,GTF2IRD1,MEF2B,CREB5,ATP1B1,ITPR2,GUCY1A2,PLCB1,GNAI1,IRS2,KCNMB4,AKT3,ADRB1,KCNMB3,PRKG1,PRKG2,ADCY6,ATP2B4,ATP2B1,NOS3,ATP1A3,MEF2C |
| 2.403e-02 | -3.73 | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_UP | 152 | 23 | 17377 | 1707 |
MPZL3,PRKAA2,RGS16,ANTXR2,CDH26,NBL1,MXI1,ALOX5AP,PNRC1,MYO10,CNTNAP3,KCNH5,LITAF,SLITRK5,NRN1,WNT11,P2RY1,ZFYVE9,SLC30A4,MPPED2,TNFRSF1A,HSPA2,IL1RAP |
| 2.407e-02 | -3.73 | guanyl ribonucleotide binding | molecular function | GO:0032561 | 387 | 50 | 17224 | 1680 |
MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,PDE10A,RAP2A,RASD2,EHD3,RAB26,PRKG1,PRKG2,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,RAPGEF2,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GBP1,GNAO1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD |
| 2.407e-02 | -3.73 | negative regulation of platelet activation | biological process | GO:0010544 | 18 | 5 | 17256 | 1658 |
ABAT,UBASH3B,PRKCD,NOS3,PRKG1 |
| 2.407e-02 | -3.73 | notochord development | biological process | GO:0030903 | 18 | 5 | 17256 | 1658 |
YAP1,ID3,WNT11,COBL,GLI1 |
| 2.407e-02 | -3.73 | negative regulation of oxidative stress-induced neuron death | biological process | GO:1903204 | 18 | 5 | 17256 | 1658 |
PRKN,RACK1,ATF4,NCOA7,FZD1 |
| 2.409e-02 | -3.73 | GO_MEMBRANE_DEPOLARIZATION | MSigDB lists | GO_MEMBRANE_DEPOLARIZATION | 58 | 11 | 17377 | 1707 |
SCN5A,SCN1B,CACNA1E,SCN8A,CACNB2,ANK2,CHRNA6,SCN2A,CACNB4,CACNA2D1,SCN3A |
| 2.409e-02 | -3.73 | POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN | MSigDB lists | POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_DN | 58 | 11 | 17377 | 1707 |
QSOX1,GCNT2,RND3,RPS11,RPL21,NTRK3,FIG4,RPS23,TPT1,GLI1,RPL34 |
| 2.409e-02 | -3.73 | GO_L_AMINO_ACID_TRANSPORT | MSigDB lists | GO_L_AMINO_ACID_TRANSPORT | 58 | 11 | 17377 | 1707 |
SLC7A1,SERINC5,SLC6A9,SLC7A11,SLC36A1,SLC7A5,SERINC2,SLC36A4,SLC1A3,SLC7A2,SLC43A1 |
| 2.410e-02 | -3.73 | ELO | pfam domains | PF01151 | 7 | 3 | 17054 | 1666 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.410e-02 | -3.73 | Sprouty | pfam domains | PF05210 | 7 | 3 | 17054 | 1666 |
SPRY4,SPRED3,SPRY2 |
| 2.410e-02 | -3.73 | TGF_beta_GS | pfam domains | PF08515 | 7 | 3 | 17054 | 1666 |
BMPR1A,ACVR1,ACVR1C |
| 2.411e-02 | -3.72 | GO_ACTIVIN_BINDING | MSigDB lists | GO_ACTIVIN_BINDING | 12 | 4 | 17377 | 1707 |
ACVR2A,ACVR2B,ACVR1,TGFBR3 |
| 2.411e-02 | -3.72 | GO_CELLULAR_RESPONSE_TO_CHOLESTEROL | MSigDB lists | GO_CELLULAR_RESPONSE_TO_CHOLESTEROL | 12 | 4 | 17377 | 1707 |
LRP6,HMGCS1,MLC1,GPLD1 |
| 2.411e-02 | -3.72 | GO_CEREBRAL_CORTEX_GABAERGIC_INTERNEURON_DIFFERENTIATION | MSigDB lists | GO_CEREBRAL_CORTEX_GABAERGIC_INTERNEURON_DIFFERENTIATION | 12 | 4 | 17377 | 1707 |
DLX2,RAC3,LHX6,NKX2-1 |
| 2.411e-02 | -3.72 | GO_OLIGOPEPTIDE_BINDING | MSigDB lists | GO_OLIGOPEPTIDE_BINDING | 12 | 4 | 17377 | 1707 |
GSTM3,GSTM2,GSTM4,PTGES |
| 2.411e-02 | -3.72 | GO_GUANYLATE_KINASE_ACTIVITY | MSigDB lists | GO_GUANYLATE_KINASE_ACTIVITY | 12 | 4 | 17377 | 1707 |
DLG2,MPP1,MAGI3,MPP2 |
| 2.411e-02 | -3.72 | GO_CARTILAGE_MORPHOGENESIS | MSigDB lists | GO_CARTILAGE_MORPHOGENESIS | 12 | 4 | 17377 | 1707 |
LRP6,MSX1,SNAI2,MEF2C |
| 2.411e-02 | -3.72 | GO_NAD_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NAD_BIOSYNTHETIC_PROCESS | 12 | 4 | 17377 | 1707 |
NMNAT3,PNP,KMO,QPRT |
| 2.411e-02 | -3.72 | GO_MECHANOSENSORY_BEHAVIOR | MSigDB lists | GO_MECHANOSENSORY_BEHAVIOR | 12 | 4 | 17377 | 1707 |
FOXP2,SLC1A3,NRXN1,ETV1 |
| 2.411e-02 | -3.72 | GO_POSITIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | 12 | 4 | 17377 | 1707 |
BBC3,DAB2IP,XBP1,ERN1 |
| 2.411e-02 | -3.72 | GO_HEART_FORMATION | MSigDB lists | GO_HEART_FORMATION | 12 | 4 | 17377 | 1707 |
SMARCD3,BMPR1A,BMP4,MEF2C |
| 2.411e-02 | -3.72 | MODULE_272 | MSigDB lists | MODULE_272 | 12 | 4 | 17377 | 1707 |
BLVRB,ALDOA,ALDH1L1,PYCR1 |
| 2.411e-02 | -3.72 | GO_I_KAPPAB_PHOSPHORYLATION | MSigDB lists | GO_I_KAPPAB_PHOSPHORYLATION | 12 | 4 | 17377 | 1707 |
DAB2IP,CHUK,TLR3,TLR4 |
| 2.411e-02 | -3.72 | GO_NEGATIVE_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT | 12 | 4 | 17377 | 1707 |
USP2,MSTN,DKK1,TLL2 |
| 2.411e-02 | -3.72 | GO_GLUCOSE_IMPORT | MSigDB lists | GO_GLUCOSE_IMPORT | 12 | 4 | 17377 | 1707 |
SLC2A12,SESN2,SLC2A13,SLC2A6 |
| 2.411e-02 | -3.72 | GO_SEROTONIN_METABOLIC_PROCESS | MSigDB lists | GO_SEROTONIN_METABOLIC_PROCESS | 12 | 4 | 17377 | 1707 |
MAOA,BTBD9,RNF180,PDE1B |
| 2.411e-02 | -3.72 | chr13q11 | MSigDB lists | chr13q11 | 12 | 4 | 17377 | 1707 |
IL17D,LATS2,GJB2,CRYL1 |
| 2.411e-02 | -3.72 | GO_CELLULAR_RESPONSE_TO_EPINEPHRINE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_EPINEPHRINE_STIMULUS | 12 | 4 | 17377 | 1707 |
RYR2,PDE4D,ATP2B4,SNCA |
| 2.411e-02 | -3.72 | GO_MEMBRANE_TUBULATION | MSigDB lists | GO_MEMBRANE_TUBULATION | 12 | 4 | 17377 | 1707 |
PACSIN1,FNBP1L,SNX9,PACSIN3 |
| 2.411e-02 | -3.72 | HASINA_NOL7_TARGETS_DN | MSigDB lists | HASINA_NOL7_TARGETS_DN | 12 | 4 | 17377 | 1707 |
CD55,MET,EML1,CD53 |
| 2.413e-02 | -3.72 | MAP kinase kinase kinase activity | molecular function | GO:0004709 | 81 | 14 | 17224 | 1680 |
EPHA3,FGFR4,TYRO3,IGF1R,MAP3K21,NTRK3,ROR1,EPHB6,MET,EPHB1,DDR1,MAP3K20,FGFR1,PDGFRB |
| 2.413e-02 | -3.72 | coenzyme binding | molecular function | GO:0050662 | 281 | 38 | 17224 | 1680 |
GPT2,MOCOS,GCAT,DHCR24,UGDH,CBS,CTBP2,ABAT,PHGDH,TXNRD3,KCNAB1,SOAT2,AADAT,KMO,PHYKPL,PARP9,NOS3,GLDC,HMGCR,CTH,MICAL2,GAPDH,ALDH2,CYB5R2,FASN,OGDHL,LDHD,ETNPPL,PLOD2,FMO4,P4HA2,BDH2,PAM,P4HA1,SQLE,HPGD,DHCR7,CRYL1 |
| 2.416e-02 | -3.72 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN | 349 | 46 | 17377 | 1707 |
TTC39B,IGFBP6,ITPRIP,LPCAT2,IL13RA1,ABHD6,PCDH7,PLS3,SLC30A4,SMTN,SERINC2,SH3PXD2B,ARL4D,MAST4,FKBP14,PERP,CARD6,PXN,PNP,AGPAT4,GJB2,TES,VLDLR,MAFB,PHACTR2,PRDM1,RAB38,ARRDC4,DSP,HOMER3,GNAI1,TMEM154,HPSE,P4HA2,FAM114A2,SLC7A5,INPP4B,PAM,RAB31,BMP1,AHNAK2,TANC2,DOCK6,STON2,SFN,DCBLD1 |
| 2.417e-02 | -3.72 | GLABLOOD | prints domains | PR00001 | 12 | 4 | 4652 | 458 |
PRRG1,PROS1,GAS6,PRRG4 |
| 2.420e-02 | -3.72 | regulation of glucose metabolic process | biological process | GO:0010906 | 98 | 16 | 17256 | 1658 |
PRKN,PPP1R3D,SORBS1,SESN2,PDK1,C1QTNF3,PFKFB2,PHLDA2,LEPR,GPLD1,IRS2,ENPP1,PMAIP1,PPARGC1A,SLC45A3,IGFBP3 |
| 2.427e-02 | -3.72 | Sprouty | interpro domains | IPR007875 | 7 | 3 | 18492 | 1811 |
SPRY4,SPRED3,SPRY2 |
| 2.427e-02 | -3.72 | GS_dom | interpro domains | IPR003605 | 7 | 3 | 18492 | 1811 |
BMPR1A,ACVR1,ACVR1C |
| 2.427e-02 | -3.72 | ELO_fam | interpro domains | IPR002076 | 7 | 3 | 18492 | 1811 |
ELOVL4,ELOVL7,ELOVL3 |
| 2.427e-02 | -3.72 | Dimeric_a/b-barrel | interpro domains | IPR011008 | 7 | 3 | 18492 | 1811 |
NECAB2,NECAB1,NIPSNAP3B |
| 2.427e-02 | -3.72 | Mss4-like_sf | interpro domains | IPR011057 | 7 | 3 | 18492 | 1811 |
MSRB3,CENPV,TPT1 |
| 2.433e-02 | -3.72 | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_DN | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_DN | 177 | 26 | 17377 | 1707 |
OPLAH,IGFBP6,IL15,TBC1D1,DOCK1,PRKAR2B,PRDM1,CD40,DSP,PHLDA2,CPEB1,HERPUD1,TIAM2,WARS,ISG20,F3,ID3,TLR3,KIAA1671,EEF2,PMAIP1,SLC22A18,SLC7A5,SLC16A9,TSPAN13,LIMCH1 |
| 2.433e-02 | -3.72 | GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_UP | MSigDB lists | GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_UP | 177 | 26 | 17377 | 1707 |
GNG12,USP2,CKAP2,WWC1,FEZ1,PSD3,MARS,PLEKHA1,ATP1B1,SAV1,TXNRD3,SLC7A1,NELL2,IKZF3,KIAA0895,NCAM2,MCF2L,LAMB1,FHIT,PJA1,CDH2,NKX2-8,NR3C2,NEB,TLL2,GLI1 |
| 2.434e-02 | -3.72 | cellular response to steroid hormone stimulus | biological process | GO:0071383 | 198 | 28 | 17256 | 1658 |
MSTN,NR6A1,HNF4G,NR4A1,RBFOX2,ESRRG,FHL2,ASS1,YAP1,ABCC2,NEDD4,DDIT4,PLPP1,FBXO32,PMEPA1,EIF4EBP1,GRIP1,BMP4,KLF9,PPARGC1A,ERRFI1,PCK2,NR3C2,ZFP36L2,SMYD3,ATP2B1,ATP1A3,HEY1 |
| 2.435e-02 | -3.72 | FERM/acyl-CoA-bd_prot_sf | interpro domains | IPR014352 | 51 | 10 | 18492 | 1811 |
FRMPD3,EPB41L5,EPB41L3,PLEKHH2,FARP1,MYO10,PTPN13,PTPN21,TLN2,FRMD5 |
| 2.435e-02 | -3.72 | MARTINEZ_RB1_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_TARGETS_DN | 501 | 63 | 17377 | 1707 |
COL9A3,TRIM2,ACSL1,ALOX5AP,PRSS12,ST14,KLHL13,ESRP1,FHDC1,MSR1,PLXNA2,GTF2IRD1,PKP2,COL18A1,CHAC1,SFXN3,CANX,DDR1,TNFRSF19,PFN2,AARS,GAS1,NEO1,HMGCS1,IDI1,GRHL1,AFF2,ZNF521,TSC22D1,TMED9,MARCKS,CTTN,ESD,SLC45A3,RPL26,MEIS2,KDM5B,MYO10,GJB2,HOMER2,PANK1,RPL21,LITAF,ATF7IP2,NFIA,EFNA3,SHISA2,ATF3,ACVR2B,ATP11A,ARRDC4,ZDHHC14,FAM162A,CEBPB,SLC39A14,PMEPA1,PLOD2,SLC7A5,GRB10,UNC5B,SLC1A5,TC2N,SIX2 |
| 2.435e-02 | -3.72 | GO_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS | MSigDB lists | GO_SENSORY_PERCEPTION_OF_MECHANICAL_STIMULUS | 144 | 22 | 17377 | 1707 |
COL4A3,FZD4,OTOGL,GABRB2,GJB2,HOMER2,TJP1,SLC1A3,HOXA1,PGAP1,FGFR1,EYA4,ZNF354A,PDZD7,WFS1,MARVELD2,ITGA2,FAM107B,TFAP2A,MYO6,SPRY2,SNAI2 |
| 2.435e-02 | -3.72 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | 144 | 22 | 17377 | 1707 |
MVK,RUNX2,COL4A4,SCN8A,CD276,MORC4,PLS1,ATF3,CD40,NPDC1,SEL1L3,DDR1,BEX2,SMPDL3B,FKBP11,GJC1,TRIB3,MYADM,TPM1,PTPRE,DDIT3,B4GALT6 |
| 2.435e-02 | -3.72 | GSE6259_33D1_POS_DC_VS_BCELL_UP | MSigDB lists | GSE6259_33D1_POS_DC_VS_BCELL_UP | 144 | 22 | 17377 | 1707 |
CFH,IL15,STXBP6,MGST3,FOXN3,ITGA6,CALCRL,ADAMTS6,IL13RA1,GAS6,SPATS2L,CDC42BPA,MKX,LGI2,FKBP9,PPM1E,PAM,TMEM117,PCOLCE2,RAPGEF5,PERP,SLC16A10 |
| 2.443e-02 | -3.71 | ATPase_P-typ_TM_dom_sf | interpro domains | IPR023298 | 37 | 8 | 18492 | 1811 |
ATP11A,ATP9A,ATP10D,ATP8A1,ATP7B,ATP2B1,ATP2B4,ATP1A3 |
| 2.443e-02 | -3.71 | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1084 | 126 | 17377 | 1707 |
NEK10,ACVR1,AVPI1,ACSL1,FGF13,IL15,AKAP5,GATA3,NTRK3,LCP2,PRKCA,SNX9,PIBF1,PPP1R9A,NOS1AP,TLR3,CDC14B,ITGB3,RAP2A,BCL6,ACVR2A,DAB2IP,MARCKS,TLR4,HSPA2,RASGRP1,PRKACB,PDGFRB,SNAI2,IGFBP3,FZD1,TNK2,GCNT2,FZD4,TGFA,LRRK2,ADCY1,PRKAR2B,WNT11,ACVR2B,RARRES2,CD40,FGFR1,SNCA,SMAD3,INHBC,NRG3,GPRC5B,NCKAP1L,WFS1,ITGA2,ERN1,TNFRSF1A,DUSP19,BMP1,TNFSF15,HGF,DIRAS1,BMPR1A,NRP1,PPARGC1A,MAPK10,MAGI2,MID1,CNTN1,MEF2C,TNIK,BMPR2,EDA2R,FBXO4,FZD8,JDP2,LRP4,SORBS3,GAS6,P2RY1,PKN1,NDFIP2,TNFRSF19,PFN2,TPD52L1,BMP6,RNF180,RASD2,PRKCD,GHR,SREBF1,ADCY6,AFAP1L2,IQGAP3,TNFRSF11A,SPRY2,SYK,HMGCR,FGFR4,VEGFC,PAK1,DISC1,MSTN,RAPGEF2,VLDLR,DUSP9,PRICKLE1,STRADB,WWC1,ARRDC4,TLR6,PLCB1,GPLD1,GPR37,MAPKAPK2,PTPRC,TRIB3,DOCK7,PELI2,THBS4,CSF1,MAP2K6,XBP1,INHBE,LRRK1,BMP4,CDH2,SMYD3,ATP2B4,BTRC |
| 2.446e-02 | -3.71 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_AND_PAX3 | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_AND_PAX3 | 7 | 3 | 17377 | 1707 |
TOX,FN1,PSTPIP2 |
| 2.446e-02 | -3.71 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_7 | 7 | 3 | 17377 | 1707 |
MECOM,LPP,BCL6 |
| 2.446e-02 | -3.71 | Subcutaneous adipose tissue(PMID:22589738) | GWAS genes | Subcutaneous adipose tissue(PMID:22589738) | 11 | 5 | 2388 | 399 |
LHPP,SMAD6,STXBP6,NR3C2,KCNH5 |
| 2.448e-02 | -3.71 | GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING | 73 | 13 | 17377 | 1707 |
EPB41L5,TRIB3,TERT,PLK2,RAPGEF2,DACT1,ITGA2,LRRK2,ADD2,BMP4,NRP1,HERPUD1,MEF2C |
| 2.448e-02 | -3.71 | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_UP | 73 | 13 | 17377 | 1707 |
ARHGEF10L,SLC39A14,BACH2,MARVELD2,RAPGEF2,NSUN6,WWC1,LRP6,RNF125,DOCK5,MBNL2,LEPR,PCSK6 |
| 2.452e-02 | -3.71 | glomerulus development | biological process | GO:0032835 | 52 | 10 | 17256 | 1658 |
COL4A3,LGR4,COL4A4,HEYL,WWTR1,ACTA2,BMP4,MAGI2,PDGFRB,MEF2C |
| 2.452e-02 | -3.71 | Trim69 (tripartite motif-containing 69) | protein interactions | 70928 | 36 | 8 | 17029 | 1718 |
SVIL,GNG12,RRAS2,GNB4,DSG2,GNAI1,STOM,PACSIN3 |
| 2.452e-02 | -3.71 | C16orf58 (chromosome 16 open reading frame 58) | protein interactions | 64755 | 36 | 8 | 17029 | 1718 |
TCTN2,BMPR2,ACVR2A,PTPRS,BMPR1A,ACVR2B,FGFR1,GSDME |
| 2.455e-02 | -3.71 | Transcription factor regulation in adipogenesis | WikiPathways | WP3599 | 22 | 6 | 5312 | 569 |
CEBPB,IRS2,CEBPA,PCK2,PPARGC1A,CEBPD |
| 2.458e-02 | -3.71 | Ig_sub2 | interpro domains | IPR003598 | 237 | 33 | 18492 | 1811 |
TYRO3,LRFN5,ROBO2,PTPRD,CD276,LILRB1,CADM2,HMCN1,FSTL5,NEO1,SPEG,CNTN4,LRRN1,NCAM1,JAM2,PDGFRB,IGSF3,FGFR4,UNC5C,DCC,OBSCN,SDK1,ROR1,PALLD,JAM3,FGFR1,NEGR1,NCAM2,PTK7,PTPRS,MYOM2,UNC5B,CNTN1 |
| 2.460e-02 | -3.71 | Glycolysis | SMPDB pathways | SMP00040 | 15 | 5 | 992 | 118 |
GAPDH,ENO1,ALDOA,PANK1,HK2 |
| 2.460e-02 | -3.71 | Glycogenosis- Type VII. Tarui disease | SMPDB pathways | SMP00531 | 15 | 5 | 992 | 118 |
GAPDH,ENO1,ALDOA,PANK1,HK2 |
| 2.460e-02 | -3.71 | Fanconi-bickel syndrome | SMPDB pathways | SMP00572 | 15 | 5 | 992 | 118 |
GAPDH,ENO1,ALDOA,PANK1,HK2 |
| 2.461e-02 | -3.70 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP | 136 | 21 | 17377 | 1707 |
SV2B,ALDH2,FN1,CACNA1E,ST6GAL1,XYLT1,RAPGEF4,TMEM200C,FAM117B,CBY1,SFXN3,IL18R1,DYRK1B,PPM1E,GSN,RPS6KA2,KCNAB1,BCHE,MAP2K6,ALDOC,DLG2 |
| 2.465e-02 | -3.70 | ZF_DAG_PE_2 | prosite domains | PS50081 | 61 | 12 | 12060 | 1278 |
CHN1,VAV3,CHN2,ARHGEF28,PDZD8,UNC13B,PRKCB,PRKCD,PRKCQ,CDC42BPA,PRKCA,RASGRP1 |
| 2.469e-02 | -3.70 | regulation of bone mineralization | biological process | GO:0030500 | 67 | 12 | 17256 | 1658 |
TRPM4,SMAD3,ENPP1,ACVR1,BMPR2,TFAP2A,ACVR2A,BMPR1A,BMP4,ACVR2B,BMP6,MEF2C |
| 2.469e-02 | -3.70 | death receptor activity | molecular function | GO:0005035 | 24 | 6 | 17224 | 1680 |
TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A |
| 2.469e-02 | -3.70 | tumor necrosis factor-activated receptor activity | molecular function | GO:0005031 | 24 | 6 | 17224 | 1680 |
TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A |
| 2.471e-02 | -3.70 | Apoptotic execution phase | REACTOME pathways | R-HSA-75153 | 53 | 10 | 10287 | 971 |
GSN,DSG2,PRKCD,PRKCQ,TJP1,VIM,SATB1,DSP,STK24,OCLN |
| 2.472e-02 | -3.70 | GO_SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_SULFUR_COMPOUND_BIOSYNTHETIC_PROCESS | 194 | 28 | 17377 | 1707 |
UST,CHSY3,OPLAH,GSTM2,ACSL1,MGST3,GSTM4,ELOVL7,XYLT1,ELOVL3,FASN,CBS,GSTO1,SCD,CHSY1,CHAC1,BCAN,TPK1,GLCE,GSTO2,HS3ST5,GSTM3,DSEL,HS3ST3B1,ESD,CTH,B4GALT6,HS6ST3 |
| 2.472e-02 | -3.70 | V$HNF4_Q6 | MSigDB lists | V$HNF4_Q6 | 245 | 34 | 17377 | 1707 |
CREB3L2,CGN,RASAL2,RBFOX2,C4A,KCTD12,ZIC2,FOXG1,SP8,MCU,TRPS1,FOXP2,SEC16B,COL25A1,CACNB2,PROS1,SP140,SMAD6,ETV1,PRKACB,PAK1,ATF4,MEIS2,PLS1,PRDM1,CLN5,TSKU,SLC39A14,ENPP6,MAP2K6,CAB39L,MMP16,MID1,FOXA1 |
| 2.479e-02 | -3.70 | GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 128 | 20 | 17377 | 1707 |
KCNIP3,FZD4,CRIM1,ATP1B1,GAS6,PHGDH,CD7,COL14A1,IL18R1,NUMBL,MFSD2A,ITGA2,PLEKHG1,CHRDL1,P4HA1,TOX,NRP1,TNFRSF17,NR3C2,SMPDL3A |
| 2.479e-02 | -3.70 | MODULE_324 | MSigDB lists | MODULE_324 | 128 | 20 | 17377 | 1707 |
ACSL1,LDLR,FASN,C1R,GAS6,PLS3,EFEMP1,GSN,CA2,FBN1,THBS4,FAT1,DSG2,ITGA2,BMP1,CDH17,PAM,CDH2,SLIT2,MID1 |
| 2.480e-02 | -3.70 | REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM | MSigDB lists | REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM | 51 | 10 | 17377 | 1707 |
GXYLT2,HPSE,HS3ST5,SDC3,HS3ST3B1,BCAN,B4GALT7,GPC6,GLCE,HS6ST3 |
| 2.480e-02 | -3.70 | LUI_THYROID_CANCER_CLUSTER_1 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_1 | 51 | 10 | 17377 | 1707 |
BEX4,FBN1,NR4A1,LRP4,DYNC2LI1,CTBP2,GAS6,SATB1,CEBPD,NKX2-1 |
| 2.480e-02 | -3.70 | ZHENG_IL22_SIGNALING_UP | MSigDB lists | ZHENG_IL22_SIGNALING_UP | 51 | 10 | 17377 | 1707 |
RTN1,TIFA,CELSR1,STXBP5L,MFSD2A,ALDH1L1,OXTR,ARRDC4,FZD1,STOM |
| 2.482e-02 | -3.70 | GO_NEGATIVE_REGULATION_OF_AXON_EXTENSION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_AXON_EXTENSION | 37 | 8 | 17377 | 1707 |
SEMA6B,SEMA4F,SEMA3C,NRP1,SEMA3A,SEMA6A,SEMA6C,BCL11A |
| 2.482e-02 | -3.70 | BIOCARTA_ALK_PATHWAY | MSigDB lists | BIOCARTA_ALK_PATHWAY | 37 | 8 | 17377 | 1707 |
BMPR1A,ACVR1,TGFBR3,BMP4,BMPR2,SMAD6,MEF2C,FZD1 |
| 2.482e-02 | -3.70 | GNF2_RAB3A | MSigDB lists | GNF2_RAB3A | 37 | 8 | 17377 | 1707 |
CAMK2N1,KIF5C,SV2B,RGS7,SH3GL2,STXBP1,RAB6B,EHD3 |
| 2.482e-02 | -3.70 | GO_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | MSigDB lists | GO_HETEROPHILIC_CELL_CELL_ADHESION_VIA_PLASMA_MEMBRANE_CELL_ADHESION_MOLECULES | 37 | 8 | 17377 | 1707 |
FAT4,PTPRD,DCHS1,CADM2,AMIGO1,NRXN1,CDH2,CBLN1 |
| 2.483e-02 | -3.70 | superpathway of tryptophan utilization | BIOCYC pathways | HUMAN_PWY66-401 | 32 | 8 | 902 | 105 |
NMNAT3,ALDH2,TDO2,KMO,MAOA,CYP2U1,QPRT,CYP1B1 |
| 2.483e-02 | -3.70 | GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 297 | 40 | 17377 | 1707 |
LATS2,IGFBP6,LGR4,LRP4,RGS20,NOTUM,KREMEN1,PPP2R3A,SKI,DACT1,LRP6,DAB2IP,BARX1,SNAI2,FZD1,GLI1,TRPM4,DISC1,WLS,LRRK2,PRICKLE1,YAP1,CBY1,WNT11,TSKU,DKK1,SMAD3,TCF7L1,TMEM237,GPRC5B,TERT,WWTR1,MCC,GRB10,LRRK1,CDH2,MLLT3,BTRC,CTNND2,DDIT3 |
| 2.483e-02 | -3.70 | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP | 169 | 25 | 17377 | 1707 |
DYRK3,ACSL1,REL,RAPGEF2,ELOVL7,HECW2,CHAC1,SAV1,SNX9,PHLDA2,DDIT4,OTUD1,TIFA,PIK3AP1,PMAIP1,ZNF697,MFSD2A,XBP1,STARD4,SLC7A5,PLD1,GEM,ATP2B1,DUSP1,LAMP3 |
| 2.494e-02 | -3.69 | TSP1 | smart domains | SM00209 | 65 | 13 | 9493 | 1056 |
ADAMTS17,UNC5C,ADGRB3,WISP3,ADAMTS3,ISM1,THSD4,THSD7B,ADAMTS6,UNC5B,THSD1,HMCN1,ADGRB2 |
| 2.503e-02 | -3.69 | Toxicity of botulinum toxin type E (BoNT/E) | REACTOME pathways | R-HSA-5250992 | 3 | 2 | 10287 | 971 |
SV2B,SNAP25 |
| 2.503e-02 | -3.69 | Serotonin clearance from the synaptic cleft | REACTOME pathways | R-HSA-380615 | 3 | 2 | 10287 | 971 |
MAOA,ALDH2 |
| 2.503e-02 | -3.69 | MET activates STAT3 | REACTOME pathways | R-HSA-8875791 | 3 | 2 | 10287 | 971 |
HGF,MET |
| 2.506e-02 | -3.69 | positive regulation of neurotransmitter transport | biological process | GO:0051590 | 31 | 7 | 17256 | 1658 |
PRKN,RAB3B,UNC13B,KMO,STXBP1,VAMP8,SNCA |
| 2.510e-02 | -3.68 | guanyl nucleotide binding | molecular function | GO:0019001 | 388 | 50 | 17224 | 1680 |
MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,PDE10A,RAP2A,RASD2,EHD3,RAB26,PRKG1,PRKG2,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,RAPGEF2,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GBP1,GNAO1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD |
| 2.512e-02 | -3.68 | SAGIV_CD24_TARGETS_DN | MSigDB lists | SAGIV_CD24_TARGETS_DN | 44 | 9 | 17377 | 1707 |
BIK,TUFT1,ATF3,CTTN,CHAC1,EPHB6,GEM,HOMER3,ISG20 |
| 2.512e-02 | -3.68 | GO_GUANOSINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_GUANOSINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 44 | 9 | 17377 | 1707 |
MOCOS,PRTFDC1,RHOQ,MPP1,LRRK2,MPP2,AK4,DLG2,MAGI3 |
| 2.512e-02 | -3.68 | MA_MYELOID_DIFFERENTIATION_DN | MSigDB lists | MA_MYELOID_DIFFERENTIATION_DN | 44 | 9 | 17377 | 1707 |
LATS2,PDE1B,GNAO1,STAT4,XBP1,CCNG1,APBA2,KIF1B,HSPA2 |
| 2.512e-02 | -3.68 | GO_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | MSigDB lists | GO_VENTRICULAR_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT | 44 | 9 | 17377 | 1707 |
TGFBR3,DSG2,RYR2,PKP2,MARCKS,TPM1,ZFPM2,DSP,HEG1 |
| 2.515e-02 | -3.68 | dendritic branch | cellular component | GO:0044307 | 3 | 2 | 18223 | 1724 |
MAP1A,MAP2 |
| 2.515e-02 | -3.68 | collagen type IX trimer | cellular component | GO:0005594 | 3 | 2 | 18223 | 1724 |
COL9A3,COL9A2 |
| 2.515e-02 | -3.68 | Lewy body core | cellular component | GO:1990037 | 3 | 2 | 18223 | 1724 |
ATF4,HERPUD1 |
| 2.515e-02 | -3.68 | inhibin-betaglycan-ActRII complex | cellular component | GO:0034673 | 3 | 2 | 18223 | 1724 |
ACVR2A,TGFBR3 |
| 2.515e-02 | -3.68 | AIP1-IRE1 complex | cellular component | GO:1990597 | 3 | 2 | 18223 | 1724 |
DAB2IP,ERN1 |
| 2.515e-02 | -3.68 | alphav-beta3 integrin-PKCalpha complex | cellular component | GO:0035866 | 3 | 2 | 18223 | 1724 |
PRKCA,ITGB3 |
| 2.515e-02 | -3.68 | activin receptor complex | cellular component | GO:0048179 | 3 | 2 | 18223 | 1724 |
ACVR1,ACVR1C |
| 2.515e-02 | -3.68 | growth cone lamellipodium | cellular component | GO:1990761 | 3 | 2 | 18223 | 1724 |
PPP1R9A,APBB1 |
| 2.515e-02 | -3.68 | FERM_CS | interpro domains | IPR019747 | 24 | 6 | 18492 | 1811 |
EPB41L5,EPB41L3,FARP1,TLN2,FRMD5,PTPN21 |
| 2.525e-02 | -3.68 | V$HOXA4_Q2 | MSigDB lists | V$HOXA4_Q2 | 254 | 35 | 17377 | 1707 |
CXCR5,CGN,UBASH3B,CREB5,ZNF219,PGAP1,NEO1,TUBB4A,FOXP2,ZNF827,PPM1E,EOMES,ZFP36L2,NKX2-1,DPP10,BDNF,SESN2,SAV1,MBNL2,ZIC1,GPR150,ADAMTS17,IFT81,NSD1,MAP2,ITGBL1,DLG2,KLF5,BMP4,PPARGC1A,NRP1,SHOX2,ATP2B4,SFN,MEF2C |
| 2.525e-02 | -3.68 | GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT | 254 | 35 | 17377 | 1707 |
SEMA6B,DNM3,ID1,ROBO2,FGF13,LRP4,NTRK3,SEMA6A,SKI,NKX6-1,EFEMP1,CNTN4,SEMA4F,KIAA0319,ADCY6,FIG4,GFI1,SLIT2,PRKACB,SEMA6C,GPR161,DCC,RAPGEF2,VIM,DKK1,BCL11A,NRG3,PLK2,INPP5F,SEMA3C,BMPR1A,BMP4,DLX2,NRP1,SEMA3A |
| 2.525e-02 | -3.68 | V$BACH2_01 | MSigDB lists | V$BACH2_01 | 254 | 35 | 17377 | 1707 |
RPS20,ENO2,SEC24D,ASS1,NDRG2,STAT5B,RASD1,PHLDA2,NCS1,COL27A1,TUBB4A,ZNF827,SCRN1,SGK1,GFI1,ENO1,GAPDH,ATF4,NR4A1,PACSIN3,STRADB,PRDM1,GABARAPL1,TRIM9,PKN3,AKT3,ALDOA,ABI3,DIRAS1,HS3ST3B1,DDIT3,RAB30,FOXA1,SFN,LPP |
| 2.525e-02 | -3.68 | V$NFKB_C | MSigDB lists | V$NFKB_C | 254 | 35 | 17377 | 1707 |
CXCR5,TYRO3,AMOTL1,NDRG2,NOTUM,DDR1,GDPD5,IL18R1,DACH2,ARHGAP44,NOS1AP,PCBP4,PRKCD,EPHB6,RIN2,BDNF,MSX1,SESN2,EFNA3,SNAP25,FGF17,CD40,BCL11A,EBF1,CXCL10,MSC,PTPRJ,GNAO1,UACA,TNFSF15,GRIN2D,HOXB9,PTGES,PURG,SLC43A1 |
| 2.525e-02 | -3.68 | V$ER_Q6 | MSigDB lists | V$ER_Q6 | 254 | 35 | 17377 | 1707 |
PRKAA2,MXI1,BMPR2,NDRG2,ZIC2,OVOL2,FAM174B,SATB1,TRPS1,NKX6-1,TMEM53,ZNF827,MAP1A,KCNN2,CHRDL1,BCL6,CNNM2,LOXL4,RAB27B,SPRY2,ESRRG,PRDM13,KCNH5,GDPD1,ATOH1,SPATA7,ZNF711,CD37,MYADM,ERN1,ALDOA,B3GALT2,DLG2,ZBTB20,MID1 |
| 2.525e-02 | -3.68 | central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype | COSMIC cancer mutations | central_nervous_system-brainstem-primitive_neuroectodermal_tumour-medulloblastoma-WNT_subtype | 187 | 27 | 17385 | 1698 |
ARHGAP26,CARS,VAV3,RASAL2,DCC,EPS8,EDEM3,GRID1,CCDC85A,WDFY4,FAM13A,GUCY1A2,MAGI3,NEGR1,LMLN,BACH2,MAP7,CLMN,NBEA,DLG2,PPP2R2B,NRP1,MAGI2,TBC1D4,IL1RAP,XKR4,FRMD5 |
| 2.526e-02 | -3.68 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma | 221 | 31 | 17385 | 1698 |
DMXL2,PHACTR3,PTPRD,CRIM1,THSD4,LRRK2,DNAJC6,PLXNA2,WWC1,CBS,ZNF215,PRDM1,FAM198B,PLCB1,PTPRC,GRIK4,EPB41L3,NAV1,FAT4,UNC13B,GSTO2,TACC2,PRCP,SRGAP1,P4HA1,HPGD,BNIP3,DNAH5,TBC1D4,MME,CRISPLD1 |
| 2.533e-02 | -3.68 | GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_UP | MSigDB lists | GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_UP | 186 | 27 | 17377 | 1707 |
GNG12,AVPI1,DNM3,TCP11L2,TTC39B,SKAP2,ITPRIP,REL,GSTO1,SLC36A4,ATF3,BATF,LCP2,KIAA1217,HERPUD1,BATF3,CEBPB,ATXN7L1,ICA1,HK2,FAM107B,RGS10,RCN3,ZBTB20,RAPGEF5,NUDT17,HMGCR |
| 2.533e-02 | -3.68 | GSE3982_EOSINOPHIL_VS_DC_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_UP | 186 | 27 | 17377 | 1707 |
DLGAP1,NDUFA4L2,MEIS2,EDA2R,KIF5A,MLF1,MCTP2,BIK,GRK6,TNFRSF10C,KIF21B,DENND3,PRR7,COL14A1,KBTBD11,GABARAPL1,RPL34,ISG20,THBS4,FLRT3,EIF1,GRB10,TESC,IL9R,DDIT3,CES3,IGFBP3 |
| 2.533e-02 | -3.68 | GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_DN | 186 | 27 | 17377 | 1707 |
ARAP2,GALNT6,ARID5B,SELL,RASA3,IGF2BP2,ADAMTS6,STAT5B,GRK6,SLC12A6,CD7,DOCK2,CHST10,CD53,SKI,KCNMB4,TACC2,PCBP4,RUNDC3B,DSEL,INPP5F,CERS4,NCEH1,RCAN3,RRAS2,SLC16A10,GLDC |
| 2.533e-02 | -3.68 | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_DN | 186 | 27 | 17377 | 1707 |
DOC2A,MOB1B,GARS,SLC6A9,ATF4,TTC39B,PNP,RNF145,BACE1,TJP1,PRDM1,TMEM170B,SPATS2L,ZFPM2,CLN5,GAS1,COL27A1,MAGI3,PYCR1,SLC39A14,EPB41L3,TLR3,PLAGL1,TERT,WFS1,PLK2,ERN1 |
| 2.533e-02 | -3.68 | GSE4142_NAIVE_VS_MEMORY_BCELL_UP | MSigDB lists | GSE4142_NAIVE_VS_MEMORY_BCELL_UP | 186 | 27 | 17377 | 1707 |
ACVR1,TTC39B,BMPR2,SLC36A1,GALNT6,TGFA,SDC3,KIF5C,CD40,DSP,TEX9,F3,NKX6-1,FKBP9,NUMBL,KCNAB1,TFAP2A,KIAA0513,ACVR2A,PTPRN2,ZNF474,FAM149A,HOXD13,RCAN3,KIF1B,DIRC2,TBC1D8 |
| 2.533e-02 | -3.68 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | 186 | 27 | 17377 | 1707 |
FADS1,HBG2,ALDH2,AASS,MPP1,ATP8A1,CR2,MAFB,CTBP2,SYNJ2BP,ITPR2,HOPX,RNF141,TUBB4A,ID3,GSN,SIPA1L2,CD37,AADAT,OSBPL5,PLD1,TMEM37,NRP1,PTPRE,SYK,FES,MEF2C |
| 2.533e-02 | -3.68 | GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_DN | 186 | 27 | 17377 | 1707 |
DPP10,INTU,VNN2,ITGB7,SPATA6,TNFSF13B,NFIA,WDFY4,BBS9,DOCK2,CHD5,GSN,TIFA,ICA1,GPRIN1,TDO2,GNB4,NCOA7,CDH17,PAM,LIN7A,IPCEF1,VWA5A,APBA2,PTPRE,SYK,GATM |
| 2.533e-02 | -3.68 | GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 186 | 27 | 17377 | 1707 |
CREB3L2,ITGB7,ALDH2,KDM5B,PRSS12,LPCAT2,WLS,SPATA6,CYTH3,ARID5B,SPATA13,GPR180,RABAC1,ZDHHC14,CLN5,TTC28,ATP10D,STK24,FBXO32,CA2,KMO,P4HA1,SVIL,FAM84B,ERRFI1,GFI1,AGL |
| 2.533e-02 | -3.68 | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_UP | MSigDB lists | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_UP | 186 | 27 | 17377 | 1707 |
NDUFA4L2,GPR63,EVL,CELSR1,LGALS3,CYB5R2,DNAJC6,OVOL2,COTL1,ATP11A,EYA4,FHOD3,DKK1,BCL11A,TMCO3,KIAA0895,RALGPS2,PIK3AP1,COL25A1,WWTR1,SGK3,ADCY6,ZNF474,SLC16A9,SPRY4,SERPINH1,SPRED3 |
| 2.533e-02 | -3.68 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN | 186 | 27 | 17377 | 1707 |
MID2,ZNF516,GPR65,ST6GAL1,DCHS1,ATF7IP2,SATB2,COTL1,ABAT,PLEKHA1,LCP2,SKAP1,SATB1,TPK1,CD53,PTPRC,ID3,BAG3,ABLIM1,NELL2,BACH2,ACVR2A,SGK1,BNIP3,HGF,GRB10,MAPK13 |
| 2.533e-02 | -3.68 | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | 186 | 27 | 17377 | 1707 |
CD55,GAPDH,ACSL1,PDK1,LGALS3,CKAP2,BIK,EDEM3,BNIP3L,CR2,SLC12A6,BATF,INTS6,PGAP1,HEG1,CYP51A1,SLC39A14,GSN,GALNT1,GYPC,IKZF5,INSIG1,ALDOC,KLF9,LRRK1,SPRY2,LPP |
| 2.533e-02 | -3.68 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | 186 | 27 | 17377 | 1707 |
CARD6,HBG2,ACSL1,KDM5B,RNF144A,ST14,SLC39A8,STAT4,YPEL2,ACO1,ASS1,CALCRL,RNF125,VIM,PLEKHA1,MCOLN2,SMAD3,GSN,SEC16B,SLC30A4,GYPC,KMO,ATRNL1,DAB2IP,SLC16A9,LIFR,DIRC2 |
| 2.533e-02 | -3.68 | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_MAC_DN | 186 | 27 | 17377 | 1707 |
RIN2,IL13RA1,OVOL2,RAC3,STEAP1,DOK5,DCBLD2,PLS3,TTC1,GPR15,PEMT,RAB31,INPP4B,BBC3,PTPRN2,NAP1L3,DLG2,IQSEC2,PTPRCAP,MYO6,TPM1,RRAS2,DHCR7,PRKACB,STOM,ZNF629,DUSP1 |
| 2.533e-02 | -3.68 | regulation of response to reactive oxygen species | biological process | GO:1901031 | 45 | 9 | 17256 | 1658 |
GPR37,SESN2,LRRK2,HGF,PDE8A,RACK1,MET,SESN1,PYCR1 |
| 2.533e-02 | -3.68 | regulation of release of cytochrome c from mitochondria | biological process | GO:0090199 | 45 | 9 | 17256 | 1658 |
BBC3,HGF,PRKN,HRK,BNIP3,PMAIP1,FAM162A,BIK,PRELID1 |
| 2.533e-02 | -3.68 | gluconeogenesis | biological process | GO:0006094 | 45 | 9 | 17256 | 1658 |
GAPDH,ATF4,ENO2,ALDOC,ALDOA,ATF3,PPARGC1A,PCK2,ENO1 |
| 2.535e-02 | -3.67 | metal ion binding | molecular function | GO:0046872 | 4090 | 432 | 17224 | 1680 |
DOC2A,MYCBP2,ADAL,ACVR1,PDE1B,ATP8A1,LDLR,GATA3,ADAMTS6,PRKCA,CA8,AARS,EYA4,STK24,NCS1,PCDH7,TRPS1,SKI,EPDR1,MOK,IKZF5,ZFYVE28,RAP2A,SP140,CPE,SMAD9,ACVR1C,NR6A1,MSRB3,EFHC1,KCND3,ACVR2B,F12,CA13,GNAI1,ENPP1,ZNF266,SH3RF1,CCBE1,ENTPD7,ATP7B,BMP1,ZBTB20,ERCC5,NRP1,SPOCK3,LPP,CARS,LATS2,KLF8,CELSR1,ZHX3,CYP2J2,ITGA6,ZNF25,SLC1A3,ADSSL1,HPCAL4,CHD5,PRRG4,MECOM,CHN1,ABLIM1,GBGT1,MSMO1,APLF,ZIC5,CPXM2,LMAN2,CADPS2,LOXL4,MOXD1,ZNF518B,MAST4,GLIS1,RIMS2,ZNF385A,RNF152,TBC1D8B,VLDLR,DCHS1,EFHC2,ZNF605,FHL2,RYR2,NSD2,PLS1,C1R,ZBBX,CDC42BPA,PLCB1,MBNL2,ZNF558,CPEB1,MMP15,DAGLA,RIMKLB,ADAMTS3,THBS4,QPCTL,MATN2,CDH17,CDH2,SMYD3,AMPD1,CSRP2,ACSM3,PLA2G4A,NUDT10,ZNF516,RNF144A,GALNT12,GALNT6,ZNF311,NRXN1,DDR1,NUDT12,ZFYVE9,RNF150,ZNF827,NELL2,ZNF438,PDE4D,PJA1,ZNF365,MYT1,DZANK1,NECAB1,RNF145,ADCY1,PRKCQ,ATP1B1,PYGO1,ASPH,ATP10D,ZNF618,METAP1D,ISG20,SNCA,ZNF396,ZNF711,IKZF3,PDLIM3,PRKCB,BEX3,TDO2,ZNF697,ZNF704,PAM,RCN3,P4HA1,KLF5,BMPR1A,NR3C2,MID1,PLSCR4,ATP9A,PLAG1,CBS,GAS6,CREB5,ZNF219,INPP1,COL27A1,KDM7A,MGAT1,NPTXR,TBC1D9,GFI1,SMAD6,ZFP36L2,SMPDL3A,B4GALT6,PDLIM7,TRPM4,VAV3,PXN,ARAP2,ARHGEF28,CLYBL,CACNA1E,RAPGEF2,RASA3,ATP11A,ZNF714,ZIC1,HEG1,GALNT3,ZFP62,NSD1,PCDHB7,PLOD2,TERT,GNAO1,PCGF2,PGM2L1,NEK11,LRRK1,B4GALT7,ATP2B4,TPT1,NUDT17,PHC1,ATP1A3,TLL2,TRIM2,TRIM16,SYT12,LMCD1,ITPR2,MGAT5B,ABAT,SYT14,IKZF2,DNER,HMCN1,FSTL5,PLS3,CYP51A1,TUBB4A,ADPRHL1,FKBP9,RUFY4,PPM1E,RPS6KA2,MPPED2,MYRIP,GALNT18,ENO1,SLIT2,PRKACB,RASGRP1,ZNF391,CYP1B1,ITGB7,TNK2,KCNIP3,MARK1,CEMIP2,ATOX1,GDPD1,ZNF565,RNF44,NT5DC2,EML1,TRIM9,GSN,KLF12,P4HA2,ERN1,TC2N,BCL11B,PRKAA2,LONRF1,MOCOS,ZNF395,SEC24D,ZCCHC24,RIMKLA,YPEL2,CYP4V2,ZNF215,ZIC2,GALNT13,SCD,CHSY1,PCDHB14,RNF141,EFEMP1,RNF180,GALNT1,ZBTB38,PRTFDC1,CA2,ZNF354A,ZNF440,GATA2,FRAS1,PDE10A,EBF4,ADCY6,LIMCH1,RNF148,NOS3,ZNF629,CHSY3,PCDH10,CDH26,MID2,HBG2,RNF170,MGAT4B,TCEA3,EDEM3,OBSCN,PDE8A,GALNT17,PRDM1,LHPP,STEAP1,AMDHD1,PLAGL1,FAT1,EGFL7,RNF122,TESC,MME,PRKN,NEK10,ZSWIM5,CELSR3,LPCAT2,MORC4,COL18A1,ZNF83,RNF24,BCL6B,LACC1,CANX,PCLO,CYP26A1,SP8,ZSCAN5A,SCIN,RIDA,ZNF362,IDI1,UNC13B,SETDB2,PDZD8,LHX6,BCL6,ZNF521,ACVR2A,STEAP3,PROS1,ZNF488,ZNF460,SP140L,SNAI2,GLI1,IGFBP3,GCA,ANTXR2,CSN2,PRDM13,TES,ACO1,RNF125,EFCC1,ZNF569,BCL11A,SMAD3,RANBP2,ZNF93,LMLN,TRIM34,RNF217,ITGA2,FAAP20,RNF130,CYP2U1,ZNF701,PSPH,MAST1,MAN2B2,PCDH18,DYRK3,NECAB2,ENO2,BMPR2,CLGN,LRP4,MCTP2,CLSTN2,SELL,PRDM8,HBE1,SLX1B,OVOL2,PPP2R3A,FOXP2,CHN2,GTSF1,PRKCD,EHD3,DSG2,TRIM3,MARCH3,PRICKLE2,KLF9,PCK2,TNFRSF11A,FKBP14,ATP2B1,MOB1B,MICAL2,USP2,KDM5B,HNF4G,ESRRG,NR4A1,CRIP2,LITAF,ASAP3,NUAK2,OGDHL,PRICKLE1,PRRG1,AGAP2,ZFPM2,EXOG,GALNT14,MGMT,SMPDL3B,RERE,EBF1,ADAMTS17,DDAH1,FAT4,L3MBTL4,FBN1,ZNF214,ZNF474,ZNF808,GEM,THAP10,RNF157,MAP3K20,MMP16,CACNA2D1,ZNF235 |
| 2.547e-02 | -3.67 | GO_PROTEOGLYCAN_METABOLIC_PROCESS | MSigDB lists | GO_PROTEOGLYCAN_METABOLIC_PROCESS | 81 | 14 | 17377 | 1707 |
UST,CHSY3,HPSE,BMPR2,XYLT1,HS3ST5,DSEL,CHSY1,HS3ST3B1,BCAN,SPOCK3,B4GALT7,GLCE,HS6ST3 |
| 2.547e-02 | -3.67 | GO_ENTRY_INTO_CELL_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION | MSigDB lists | GO_ENTRY_INTO_CELL_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION | 81 | 14 | 17377 | 1707 |
EFNB2,TYRO3,ITGB7,CD55,KPNA3,ITGA2,LDLR,VAMP8,ITGB3,CR2,GAS6,NCAM1,SLC1A5,LAMP3 |
| 2.547e-02 | -3.67 | GO_MOVEMENT_IN_ENVIRONMENT_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION | MSigDB lists | GO_MOVEMENT_IN_ENVIRONMENT_OF_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION | 81 | 14 | 17377 | 1707 |
EFNB2,TYRO3,ITGB7,CD55,KPNA3,ITGA2,VAMP8,LDLR,ITGB3,CR2,GAS6,NCAM1,SLC1A5,LAMP3 |
| 2.547e-02 | -3.67 | GO_VIRAL_ENTRY_INTO_HOST_CELL | MSigDB lists | GO_VIRAL_ENTRY_INTO_HOST_CELL | 81 | 14 | 17377 | 1707 |
TYRO3,EFNB2,ITGB7,CD55,KPNA3,LDLR,VAMP8,ITGB3,ITGA2,CR2,GAS6,NCAM1,SLC1A5,LAMP3 |
| 2.547e-02 | -3.67 | GO_ENTRY_INTO_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION | MSigDB lists | GO_ENTRY_INTO_OTHER_ORGANISM_INVOLVED_IN_SYMBIOTIC_INTERACTION | 81 | 14 | 17377 | 1707 |
EFNB2,TYRO3,ITGB7,CD55,KPNA3,ITGA2,VAMP8,LDLR,ITGB3,CR2,GAS6,NCAM1,SLC1A5,LAMP3 |
| 2.547e-02 | -3.67 | GO_ENTRY_INTO_HOST | MSigDB lists | GO_ENTRY_INTO_HOST | 81 | 14 | 17377 | 1707 |
TYRO3,EFNB2,ITGB7,CD55,KPNA3,LDLR,VAMP8,ITGB3,ITGA2,CR2,GAS6,NCAM1,SLC1A5,LAMP3 |
| 2.547e-02 | -3.67 | GO_MOVEMENT_IN_HOST_ENVIRONMENT | MSigDB lists | GO_MOVEMENT_IN_HOST_ENVIRONMENT | 81 | 14 | 17377 | 1707 |
EFNB2,TYRO3,ITGB7,CD55,KPNA3,ITGA2,LDLR,VAMP8,ITGB3,CR2,GAS6,NCAM1,SLC1A5,LAMP3 |
| 2.547e-02 | -3.67 | GO_ENTRY_INTO_HOST_CELL | MSigDB lists | GO_ENTRY_INTO_HOST_CELL | 81 | 14 | 17377 | 1707 |
TYRO3,EFNB2,ITGB7,CD55,KPNA3,LDLR,VAMP8,ITGB3,ITGA2,CR2,GAS6,NCAM1,SLC1A5,LAMP3 |
| 2.547e-02 | -3.67 | GO_REGULATION_OF_POTASSIUM_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_POTASSIUM_ION_TRANSPORT | 81 | 14 | 17377 | 1707 |
DPP10,KCNIP3,ATF4,KCNN2,KCNAB1,AKAP7,AKAP5,ANK2,KCNG1,AMIGO1,ATP1B1,NOS1AP,NEDD4,NOS3 |
| 2.547e-02 | -3.67 | GO_REGULATION_OF_PROTEIN_MATURATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_MATURATION | 81 | 14 | 17377 | 1707 |
GSN,CD55,RPS6KA2,CFH,CCBE1,C4A,LRRK2,PROS1,CHAC1,F12,SUSD4,C4BPB,PRKACB,GAS1 |
| 2.548e-02 | -3.67 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_THE_CH_CH_GROUP_OF_DONORS_NAD_OR_NADP_AS_ACCEPTOR | 24 | 6 | 17377 | 1707 |
DHCR7,BLVRB,SRD5A3,DHCR24,BDH2,FASN |
| 2.548e-02 | -3.67 | GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | MSigDB lists | GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION | 24 | 6 | 17377 | 1707 |
EFNB2,ID1,NRP1,NR4A1,SLIT2,GPLD1 |
| 2.548e-02 | -3.67 | GO_REGULATION_OF_ODONTOGENESIS | MSigDB lists | GO_REGULATION_OF_ODONTOGENESIS | 24 | 6 | 17377 | 1707 |
MSX1,PAX9,RUNX2,BMP4,CSF1,TFAP2A |
| 2.548e-02 | -3.67 | CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_DN | 24 | 6 | 17377 | 1707 |
MOB1B,PHACTR2,CARD6,STOX2,RHOBTB1,PLOD2 |
| 2.548e-02 | -3.67 | IIZUKA_LIVER_CANCER_PROGRESSION_L1_G1_UP | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_L1_G1_UP | 24 | 6 | 17377 | 1707 |
FERMT2,C1R,AGL,PRCP,BNIP3L,IGFBP3 |
| 2.548e-02 | -3.67 | chr5q34 | MSigDB lists | chr5q34 | 24 | 6 | 17377 | 1707 |
GABRG2,EBF1,WWC1,GABRB2,PANK3,DUSP1 |
| 2.548e-02 | -3.67 | GO_ACETYL_COA_METABOLIC_PROCESS | MSigDB lists | GO_ACETYL_COA_METABOLIC_PROCESS | 24 | 6 | 17377 | 1707 |
MVK,AADAT,AASS,TDO2,MVD,FASN |
| 2.548e-02 | -3.67 | RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP | MSigDB lists | RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP | 24 | 6 | 17377 | 1707 |
CTTN,CDH2,VLDLR,XBP1,ZIC1,DHX32 |
| 2.548e-02 | -3.67 | GO_DEATH_RECEPTOR_ACTIVITY | MSigDB lists | GO_DEATH_RECEPTOR_ACTIVITY | 24 | 6 | 17377 | 1707 |
TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A |
| 2.551e-02 | -3.67 | FoxO signaling pathway | KEGG pathways | hsa04068 | 132 | 21 | 7161 | 730 |
PRKAA2,HOMER2,AGAP2,CHUK,SGK2,FOXG1,GABARAPL1,HOMER3,IRS2,SMAD3,FBXO32,IGF1R,PLK2,AKT3,SGK3,BCL6,SGK1,MAPK13,BNIP3,PCK2,MAPK10 |
| 2.553e-02 | -3.67 | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor | molecular function | GO:0016646 | 18 | 5 | 17224 | 1680 |
AASS,ALDH1L2,BLVRB,ALDH1L1,PYCR1 |
| 2.553e-02 | -3.67 | ATP-dependent microtubule motor activity, minus-end-directed | molecular function | GO:0008569 | 18 | 5 | 17224 | 1680 |
DYNC2H1,DNHD1,DNAH6,DNAH5,DYNC2LI1 |
| 2.555e-02 | -3.67 | regulation of cardiac conduction | biological process | GO:1903779 | 75 | 13 | 17256 | 1658 |
TRPM4,TMEM65,ANK2,EHD3,TRPC1,RYR2,ITPR2,ATP1B1,PDE4D,ASPH,ATP2B1,ATP2B4,ATP1A3 |
| 2.555e-02 | -3.67 | endoderm development | biological process | GO:0007492 | 75 | 13 | 17256 | 1658 |
SMAD3,EPB41L5,MMP15,FN1,EOMES,APELA,LAMB1,PAX9,BMPR1A,BMP4,DUSP1,DKK1,NKX2-1 |
| 2.561e-02 | -3.66 | V$MZF1_01 | MSigDB lists | V$MZF1_01 | 220 | 31 | 17377 | 1707 |
BCL11B,MN1,MXI1,FARP1,MEIS2,RNF145,AGPAT4,ANK2,BLVRB,DCHS1,NDRG2,BCL6B,NTRK3,GRK6,ZDHHC14,HOXA1,SEMA6A,HPCAL4,ARHGAP44,MAP1B,FKBP11,BCL11A,ENTPD1,GNB4,PCBP4,INHBE,PPP2R2B,SIX2,FES,RAB30,ZNF385A |
| 2.562e-02 | -3.66 | response to amine | biological process | GO:0014075 | 38 | 8 | 17256 | 1658 |
TRDMT1,PDE1B,UROS,ASIC1,ITGA2,ASS1,OXTR,GLDC |
| 2.562e-02 | -3.66 | positive regulation of response to endoplasmic reticulum stress | biological process | GO:1905898 | 38 | 8 | 17256 | 1658 |
DAB2IP,ATF3,ATF4,PMAIP1,HERPUD1,DDIT3,ERN1,XBP1 |
| 2.562e-02 | -3.66 | regulation of axon guidance | biological process | GO:1902667 | 38 | 8 | 17256 | 1658 |
SEMA3C,ZSWIM5,SEMA4F,NRP1,BMPR2,SEMA3A,SLIT2,PLXNA2 |
| 2.562e-02 | -3.66 | regulation of glycoprotein biosynthetic process | biological process | GO:0010559 | 38 | 8 | 17256 | 1658 |
NECAB2,NECAB1,IL15,BACE2,ACER2,PXYLP1,PLCB1,ALG10B |
| 2.563e-02 | -3.66 | regulation of cellular carbohydrate metabolic process | biological process | GO:0010675 | 123 | 19 | 17256 | 1658 |
PRKN,PPP1R3D,SORBS1,SESN2,PDK1,C1QTNF3,PFKFB2,P2RY1,PHLDA2,LEPR,SNCA,GPLD1,DDIT4,IRS2,ENPP1,PMAIP1,PPARGC1A,SLC45A3,IGFBP3 |
| 2.563e-02 | -3.66 | osteoblast differentiation | biological process | GO:0001649 | 123 | 19 | 17256 | 1658 |
MRC2,RUNX2,LGR4,FHL2,FASN,SATB2,WNT11,BMP6,SMAD3,WWTR1,SH3PXD2B,BMP4,RRAS2,SHOX2,SNAI2,IGFBP3,FZD1,MEF2C,GLI1 |
| 2.566e-02 | -3.66 | GTPase activity | molecular function | GO:0003924 | 291 | 39 | 17224 | 1680 |
MTG1,DNM3,RHOBTB1,RHOD,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,RND2,TUBB4A,EEF2,RASD2,RAP2A,RAB26,ARL4D,RAB27B,RRAS2,SEPT3,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,NUGGC,LRRK2,AGAP2,RAB38,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,GEM,SEPT5,RAB30,RRAGD |
| 2.574e-02 | -3.66 | YKACATTT_UNKNOWN | MSigDB lists | YKACATTT_UNKNOWN | 263 | 36 | 17377 | 1707 |
LRFN5,AMOTL1,BMPR2,FGF13,CHCHD7,PTPRD,PLAG1,OTX1,APBA1,DYNC1I1,TTC1,EFEMP1,BAG3,DACT1,PPP2R2B,MICAL2,UNC5C,BDNF,MSTN,SH2D2A,FOXN3,PRDM1,ATP1B1,ROR1,ZNF569,EBF1,PDLIM3,KLF12,KIAA0355,PLOD2,PELI2,ERN1,INPP4B,MAPK10,MLLT3,MEF2C |
| 2.577e-02 | -3.66 | CTNNB1 (catenin beta 1) | protein interactions | 1499 | 350 | 47 | 17029 | 1718 |
PRKN,LATS2,GRIK2,PKP2,HERC5,CEBPA,CHUK,PRKCA,SATB1,CTNNA2,ZFYVE9,TFAP2A,BCL6,SGK1,LRP6,GRIP1,FHIT,MET,DLGAP1,FER,TUBA1A,PTPRU,NR4A1,PTPN6,RAPGEF2,TES,PTPN13,FHL2,NSD2,YAP1,CBY1,PYGO1,ARHGAP32,FGFR1,DKK1,SMAD3,TCF7L1,PTPRJ,CCNA1,GRIN2D,KLF5,CDH2,MAGI2,KCTD1,SFN,BTRC,CTNND2 |
| 2.579e-02 | -3.66 | - | gene3d domains | 3.40.640.10 | 41 | 9 | 8148 | 867 |
GPT2,MOCOS,AADAT,GCAT,PHYKPL,ABAT,ETNPPL,CTH,GLDC |
| 2.582e-02 | -3.66 | regulation of microtubule-based process | biological process | GO:0032886 | 199 | 28 | 17256 | 1658 |
PAK1,PRKAA2,EPHA3,PHLDB2,TMEM67,FGF13,CKAP2,ARL2,FEZ1,NPM1,HDGFL3,GPSM2,MAP10,MAP1B,SNCA,GNAI1,FSD1,ARMC4,TUBB4A,RANBP2,MAP1A,MAP2,PLK2,MAP9,MET,MID1,FES,CHMP4C |
| 2.583e-02 | -3.66 | GO_ACTIN_FILAMENT | MSigDB lists | GO_ACTIN_FILAMENT | 66 | 12 | 17377 | 1707 |
PAK1,GNG12,RHOQ,WIPF3,MYO1B,FERMT2,CTTN,MYO6,PALLD,TPM1,RAC3,COBL |
| 2.583e-02 | -3.66 | LINDSTEDT_DENDRITIC_CELL_MATURATION_A | MSigDB lists | LINDSTEDT_DENDRITIC_CELL_MATURATION_A | 66 | 12 | 17377 | 1707 |
ENTPD1,RTN1,PLA2G4A,CXCL10,SLC3A2,SLC7A11,TRIM16,GBP1,STAT4,SLC7A5,ACVR2A,CD40 |
| 2.583e-02 | -3.66 | GO_REGULATION_OF_CARDIAC_CONDUCTION | MSigDB lists | GO_REGULATION_OF_CARDIAC_CONDUCTION | 66 | 12 | 17377 | 1707 |
TRPM4,TMEM65,ANK2,RYR2,TRPC1,ITPR2,PDE4D,ATP1B1,ASPH,ATP2B1,ATP2B4,ATP1A3 |
| 2.585e-02 | -3.66 | KR | smart domains | SM00130 | 16 | 5 | 9493 | 1056 |
HGF,ROR1,F12,PRSS12,KREMEN1 |
| 2.591e-02 | -3.65 | negative regulation of skeletal muscle cell proliferation | biological process | GO:0014859 | 3 | 2 | 17256 | 1658 |
EPHB1,MSTN |
| 2.591e-02 | -3.65 | kinin cascade | biological process | GO:0002254 | 3 | 2 | 17256 | 1658 |
F12,PRCP |
| 2.591e-02 | -3.65 | activation of meiosis | biological process | GO:0090427 | 3 | 2 | 17256 | 1658 |
MSX1,PLCB1 |
| 2.591e-02 | -3.65 | negative regulation of cell proliferation involved in heart morphogenesis | biological process | GO:2000137 | 3 | 2 | 17256 | 1658 |
BMP4,BMPR2 |
| 2.591e-02 | -3.65 | T-helper 2 cell differentiation | biological process | GO:0045064 | 3 | 2 | 17256 | 1658 |
GATA3,BATF |
| 2.591e-02 | -3.65 | receptor-mediated endocytosis involved in cholesterol transport | biological process | GO:0090118 | 3 | 2 | 17256 | 1658 |
LRP6,LDLR |
| 2.591e-02 | -3.65 | regulation of synaptic activity | biological process | GO:0060025 | 3 | 2 | 17256 | 1658 |
SYBU,MEF2C |
| 2.591e-02 | -3.65 | positive regulation of glutamate secretion, neurotransmission | biological process | GO:1903296 | 3 | 2 | 17256 | 1658 |
KMO,STXBP1 |
| 2.591e-02 | -3.65 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity | biological process | GO:1904217 | 3 | 2 | 17256 | 1658 |
SERINC5,SERINC2 |
| 2.591e-02 | -3.65 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological process | GO:1902162 | 3 | 2 | 17256 | 1658 |
RPL26,ZNF385A |
| 2.591e-02 | -3.65 | plasma kallikrein-kinin cascade | biological process | GO:0002353 | 3 | 2 | 17256 | 1658 |
F12,PRCP |
| 2.591e-02 | -3.65 | negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological process | GO:2001189 | 3 | 2 | 17256 | 1658 |
LILRB1,LGALS3 |
| 2.591e-02 | -3.65 | mesoderm migration involved in gastrulation | biological process | GO:0007509 | 3 | 2 | 17256 | 1658 |
EPB41L5,APELA |
| 2.591e-02 | -3.65 | positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity | biological process | GO:1904219 | 3 | 2 | 17256 | 1658 |
SERINC5,SERINC2 |
| 2.591e-02 | -3.65 | intracellular copper ion transport | biological process | GO:0015680 | 3 | 2 | 17256 | 1658 |
ATP7B,ATOX1 |
| 2.591e-02 | -3.65 | regulation of spontaneous neurotransmitter secretion | biological process | GO:1904048 | 3 | 2 | 17256 | 1658 |
PRKN,PPP1R9A |
| 2.591e-02 | -3.65 | positive regulation of serine C-palmitoyltransferase activity | biological process | GO:1904222 | 3 | 2 | 17256 | 1658 |
SERINC5,SERINC2 |
| 2.591e-02 | -3.65 | regulation of thrombin-activated receptor signaling pathway | biological process | GO:0070494 | 3 | 2 | 17256 | 1658 |
MET,SNCA |
| 2.591e-02 | -3.65 | regulation of retrograde transport, endosome to Golgi | biological process | GO:1905279 | 3 | 2 | 17256 | 1658 |
PRKN,LRRK2 |
| 2.591e-02 | -3.65 | anterograde axonal protein transport | biological process | GO:0099641 | 3 | 2 | 17256 | 1658 |
DLG2,MAP1A |
| 2.591e-02 | -3.65 | NADP catabolic process | biological process | GO:0006742 | 3 | 2 | 17256 | 1658 |
NUDT12,NUDT17 |
| 2.591e-02 | -3.65 | apoptotic process involved in luteolysis | biological process | GO:0061364 | 3 | 2 | 17256 | 1658 |
ROBO2,SLIT2 |
| 2.591e-02 | -3.65 | isopentenyl diphosphate biosynthetic process, mevalonate pathway | biological process | GO:0019287 | 3 | 2 | 17256 | 1658 |
MVK,MVD |
| 2.591e-02 | -3.65 | regulation of transforming growth factor-beta secretion | biological process | GO:2001201 | 3 | 2 | 17256 | 1658 |
LILRB1,FN1 |
| 2.591e-02 | -3.65 | regulation of mitotic cell cycle DNA replication | biological process | GO:1903463 | 3 | 2 | 17256 | 1658 |
FGFR1,BCL6 |
| 2.591e-02 | -3.65 | establishment or maintenance of neuroblast polarity | biological process | GO:0045196 | 3 | 2 | 17256 | 1658 |
DOCK7,FGF13 |
| 2.591e-02 | -3.65 | basal dendrite morphogenesis | biological process | GO:0150019 | 3 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 2.591e-02 | -3.65 | cellular detoxification of nitrogen compound | biological process | GO:0070458 | 3 | 2 | 17256 | 1658 |
GSTM3,GSTM2 |
| 2.591e-02 | -3.65 | pyridine nucleotide catabolic process | biological process | GO:0019364 | 3 | 2 | 17256 | 1658 |
NUDT12,NUDT17 |
| 2.591e-02 | -3.65 | negative regulation of satellite cell differentiation | biological process | GO:1902725 | 3 | 2 | 17256 | 1658 |
EPHB1,MSTN |
| 2.591e-02 | -3.65 | angiogenesis involved in coronary vascular morphogenesis | biological process | GO:0060978 | 3 | 2 | 17256 | 1658 |
NRP1,PDGFRB |
| 2.591e-02 | -3.65 | trunk neural crest cell migration | biological process | GO:0036484 | 3 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 2.591e-02 | -3.65 | negative regulation of thrombin-activated receptor signaling pathway | biological process | GO:0070495 | 3 | 2 | 17256 | 1658 |
MET,SNCA |
| 2.591e-02 | -3.65 | tryptophan transport | biological process | GO:0015827 | 3 | 2 | 17256 | 1658 |
SLC36A4,SLC3A2 |
| 2.591e-02 | -3.65 | response to antipsychotic drug | biological process | GO:0097332 | 3 | 2 | 17256 | 1658 |
PRKAR2B,PRKACB |
| 2.591e-02 | -3.65 | cellular response to sorbitol | biological process | GO:0072709 | 3 | 2 | 17256 | 1658 |
MAPK13,MAP2K6 |
| 2.591e-02 | -3.65 | basal dendrite arborization | biological process | GO:0150020 | 3 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 2.591e-02 | -3.65 | L-arginine import across plasma membrane | biological process | GO:0097638 | 3 | 2 | 17256 | 1658 |
SLC7A1,SLC7A2 |
| 2.591e-02 | -3.65 | L-lysine catabolic process to acetyl-CoA via saccharopine | biological process | GO:0033512 | 3 | 2 | 17256 | 1658 |
AADAT,AASS |
| 2.591e-02 | -3.65 | positive regulation of neural crest cell differentiation | biological process | GO:1905294 | 3 | 2 | 17256 | 1658 |
SEMA3C,BMP4 |
| 2.591e-02 | -3.65 | negative regulation of fibroblast growth factor production | biological process | GO:0090272 | 3 | 2 | 17256 | 1658 |
WNT11,FGFR1 |
| 2.591e-02 | -3.65 | basal dendrite development | biological process | GO:0150018 | 3 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 2.591e-02 | -3.65 | cloacal septation | biological process | GO:0060197 | 3 | 2 | 17256 | 1658 |
WNT11,BMP4 |
| 2.591e-02 | -3.65 | embryonic hindgut morphogenesis | biological process | GO:0048619 | 3 | 2 | 17256 | 1658 |
HOXD13,DACT1 |
| 2.591e-02 | -3.65 | cellular response to UV-A | biological process | GO:0071492 | 3 | 2 | 17256 | 1658 |
CERS1,MME |
| 2.591e-02 | -3.65 | gamma-aminobutyric acid biosynthetic process | biological process | GO:0009449 | 3 | 2 | 17256 | 1658 |
ABAT,SLC1A3 |
| 2.591e-02 | -3.65 | ventral trunk neural crest cell migration | biological process | GO:0036486 | 3 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 2.591e-02 | -3.65 | regulation of glutamate secretion, neurotransmission | biological process | GO:1903294 | 3 | 2 | 17256 | 1658 |
KMO,STXBP1 |
| 2.591e-02 | -3.65 | membrane depolarization during atrial cardiac muscle cell action potential | biological process | GO:0098912 | 3 | 2 | 17256 | 1658 |
SCN5A,CACNB2 |
| 2.591e-02 | -3.65 | alpha-beta T cell proliferation | biological process | GO:0046633 | 3 | 2 | 17256 | 1658 |
IL15,DOCK2 |
| 2.591e-02 | -3.65 | hydrogen sulfide biosynthetic process | biological process | GO:0070814 | 3 | 2 | 17256 | 1658 |
CBS,CTH |
| 2.591e-02 | -3.65 | trunk segmentation | biological process | GO:0035290 | 3 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 2.591e-02 | -3.65 | glycoprotein transport | biological process | GO:0034436 | 3 | 2 | 17256 | 1658 |
VLDLR,ABCG1 |
| 2.591e-02 | -3.65 | positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological process | GO:1902164 | 3 | 2 | 17256 | 1658 |
RPL26,ZNF385A |
| 2.591e-02 | -3.65 | establishment of neuroblast polarity | biological process | GO:0045200 | 3 | 2 | 17256 | 1658 |
DOCK7,FGF13 |
| 2.591e-02 | -3.65 | leucine transport | biological process | GO:0015820 | 3 | 2 | 17256 | 1658 |
SLC6A15,SLC3A2 |
| 2.591e-02 | -3.65 | regulation of branching morphogenesis of a nerve | biological process | GO:2000172 | 3 | 2 | 17256 | 1658 |
SHOX2,LRRK2 |
| 2.591e-02 | -3.65 | positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis | biological process | GO:1905312 | 3 | 2 | 17256 | 1658 |
SEMA3C,BMP4 |
| 2.591e-02 | -3.65 | mammary duct terminal end bud growth | biological process | GO:0060763 | 3 | 2 | 17256 | 1658 |
KDM5B,CSF1 |
| 2.591e-02 | -3.65 | protein localization to presynapse | biological process | GO:1905383 | 3 | 2 | 17256 | 1658 |
DLG2,MAP1A |
| 2.591e-02 | -3.65 | negative regulation of skeletal muscle satellite cell proliferation | biological process | GO:1902723 | 3 | 2 | 17256 | 1658 |
EPHB1,MSTN |
| 2.591e-02 | -3.65 | cysteine biosynthetic process | biological process | GO:0019344 | 3 | 2 | 17256 | 1658 |
CBS,CTH |
| 2.592e-02 | -3.65 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_2H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_2H_UP | 178 | 26 | 17377 | 1707 |
UST,LONRF1,TMEM63C,ARAP2,EVL,TES,UBASH3B,ST6GAL1,DSTN,XYLT1,JPH1,ARID5B,YPEL2,RASA3,CD7,SNX9,SESN1,GRPEL2,IQCK,IKZF5,INSIG1,PIK3AP1,ABI3,SLC2A6,SP140L,PHC1 |
| 2.592e-02 | -3.65 | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN | 178 | 26 | 17377 | 1707 |
COL9A3,ALDH2,SLC37A1,SIDT1,PTPN6,COBLL1,IL13RA1,SAV1,ZDHHC14,SEL1L3,WARS,ISG20,BCL11A,GSN,CA2,BACH2,RAB31,OPN3,SQLE,TSPAN13,TNFRSF17,TBC1D9,SYK,CKAP4,SCN3A,MEF2C |
| 2.592e-02 | -3.65 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | 178 | 26 | 17377 | 1707 |
KDM5B,CACNA1E,PLXNA2,FHL2,FAM117B,KIAA1217,NOVA1,SPATA7,AHRR,ENTPD1,OTUD1,ZNF362,KCNMB4,FBN1,CSF1,MARVELD2,GPR155,JAKMIP2,THAP10,APBA2,MAST4,TNFRSF11A,SMYD3,SLC16A10,SCN3A,C3orf67 |
| 2.592e-02 | -3.65 | MORF_IL4 | MSigDB lists | MORF_IL4 | 178 | 26 | 17377 | 1707 |
TNIK,GCA,MID2,STXBP5L,WISP3,GABRB2,LRP4,RNF24,SLC46A3,RAC3,DOK5,GPR19,SEMA6A,GPR15,PPM1E,SOAT2,ITGBL1,TACC2,MAP2K6,PTPRS,COL19A1,PDE4D,ST8SIA1,NR3C2,NEB,B4GALT6 |
| 2.592e-02 | -3.65 | GSE40655_FOXO1_KO_VS_WT_NTREG_DN | MSigDB lists | GSE40655_FOXO1_KO_VS_WT_NTREG_DN | 178 | 26 | 17377 | 1707 |
TRPM4,MVK,ERGIC1,WISP3,PTPN13,DSTN,LSM11,AGPAT4,TMEM126A,TNFSF13B,FHL2,NRN1,NDFIP2,CA13,SMPDL3B,PPP2R3A,BAIAP2,KIAA1958,PRCP,PPFIBP1,WDR19,HGF,MORN2,IQGAP3,VASH2,RBMS2 |
| 2.592e-02 | -3.65 | GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP | 178 | 26 | 17377 | 1707 |
QSOX1,PNRC1,SH2D2A,RNF125,TJP1,ATF3,COTL1,FNDC3A,BAIAP2,HERPUD1,ISG20,ENTPD1,CXCL10,IDI1,PIK3AP1,PMAIP1,ERN1,SLC7A5,TOX,PDE4D,ST8SIA1,GEM,PERP,SLC16A10,HMGCR,DOCK9 |
| 2.592e-02 | -3.65 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN | 178 | 26 | 17377 | 1707 |
PFKFB4,PAK1,ITGB7,AVPI1,FN1,LPCAT2,MPP1,GPR65,UBASH3B,BLVRB,VAMP8,TNFSF13B,UCHL3,FAM13A,ABHD6,RERE,CHN2,PRCP,PLXDC2,FAM168A,GAS2L3,SRD5A3,EEPD1,KIAA0513,TNFRSF11A,MEF2C |
| 2.592e-02 | -3.65 | GSE25087_TREG_VS_TCONV_ADULT_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_ADULT_UP | 178 | 26 | 17377 | 1707 |
SKAP2,GATA3,PHACTR2,ATP1B1,SKAP1,IKZF2,SLCO3A1,GPR19,HERPUD1,GABARAPL1,PLS3,GLCE,CHN1,IRS2,INHBC,TIFA,FCHO2,PIK3AP1,SLC7A5,B3GALT2,HPGD,MARCH3,IQGAP3,ATP2B4,PERP,MEF2C |
| 2.592e-02 | -3.65 | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN | MSigDB lists | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN | 178 | 26 | 17377 | 1707 |
GSTM2,EIF4E3,KDM5B,PTPN13,AGPAT4,SELL,FEZ1,STRADB,TPK1,ENTPD1,OTUD1,TIFA,DACT1,C1orf21,BCL6,SGK1,TMOD2,JAKMIP2,PLD1,RCAN3,COBL,SMYD3,KIAA1211,PKIA,SLC16A10,C3orf67 |
| 2.594e-02 | -3.65 | PLAC | interpro domains | IPR010909 | 18 | 5 | 18492 | 1811 |
ADAMTS17,ADAMTS6,ADAMTS3,THSD4,PCSK6 |
| 2.599e-02 | -3.65 | formation of primary germ layer | biological process | GO:0001704 | 115 | 18 | 17256 | 1658 |
EPB41L5,ACVR1,FN1,BMPR2,WLS,WNT11,DKK1,SMAD3,MMP15,EOMES,APELA,ITGA2,LAMB1,ITGB3,BMP4,BMPR1A,SIX2,DUSP1 |
| 2.604e-02 | -3.65 | cytosol | cellular component | GO:0005829 | 5011 | 509 | 18223 | 1724 |
ARHGAP26,TRIM16L,ADAL,PPP4R4,PDE1B,DNAJC3,VAMP8,PPFIBP2,NPM1,ENAH,CTBP2,STAT5B,CHAC1,NHP2,DOCK3,PRKCA,SNX9,RAC3,AARS,HECTD2,STK24,NCS1,NOS1AP,BAG3,TYMP,FBXO32,PMAIP1,ZFYVE28,PPFIA2,PALD1,RAP2A,KCNS3,GSTM3,PPP2R2B,COG3,PACSIN1,THSD1,GLDC,GDAP1,EIF4E3,SMAD9,DCC,KLHL3,LRRK2,DNAJC6,BNIP3L,ELMOD1,MSRB3,AGO4,PRKAR2B,SAV1,CA13,ARHGEF26,AHRR,WIPF3,SH3RF1,NCKAP1L,RASGRF2,PLK2,ALDOA,BDH2,ARHGAP28,CAB39L,MAPK13,SPRY4,TPM1,NRP1,SPART,LPP,CRYL1,CARS,LATS2,KLF8,INPPL1,EHHADH,TBC1D1,GABRB2,DHCR24,OPHN1,GTF2IRD1,TJP1,ISYNA1,GPSM2,HERC6,APBA1,DYNC1I1,ADSSL1,BBS9,CHD5,RPL13A,MECOM,CHN1,RSL24D1,PIK3AP1,APLF,MYC,FLRT3,SREBF1,SRGAP1,PRKG1,GRIP1,NCAM1,DENND1C,AGL,STXBP1,FMNL2,RPS23,EPB41L5,RPL26,PNP,MYO10,STAT4,RAPGEF4,FASN,PACSIN3,HIP1,PEX5L,SNAP25,PLCB1,CLN5,FAM162A,SPATA7,CPEB1,RIMKLB,PLEKHH2,GSTO2,SH3GL2,RPL28,PELI2,FBXO27,DHCR7,SMYD3,GVINP1,AMPD1,DOCK9,PLA2G4A,NUDT10,AMOTL1,RASAL2,RHOD,ADD2,CHUK,MAPK4,SPATS2L,LCP2,NUDT12,TBC1D30,TIAM2,ZFYVE9,EPB41L3,ASNS,ZNF438,KMO,POU5F1B,EEF1AKMT2,DACT1,ALDOC,ALDH1L1,NBEA,DAB2IP,PDE4D,RPL26L1,MYT1,DOCK8,GAB2,MYLK3,GAPDH,GARS,NECAB1,PFKFB2,NPM3,SHANK2,PANK1,PREX1,ADCY1,CBY1,PRKCQ,RAB38,TBC1D16,FGFR1,GABARAPL1,SNCA,PATJ,IRS2,ARHGAP21,IKZF3,PRKCB,BEX3,TDO2,CCNA1,WWTR1,INPP4B,HPGD,GRB10,ATG5,MAPK10,NR3C2,MID1,STON2,DENND5B,RPS20,MYO1D,FARP1,MXI1,CKAP2,ARL2,HERC5,CBS,PKN1,EPHB1,RGS7,INPP1,NEDD4,HMGCS1,PCBP4,MCF2L,GHR,RMDN2,SGK3,PRKG2,RALGAPA2,YBX3,MYO6,ERRFI1,SMAD6,SPRY2,ZFP36L2,FES,PARP9,ULBP1,PFKFB4,TRPM4,PDLIM7,B9D1,OPLAH,SLC40A1,VAV3,SYNPO2,PXN,ARAP2,ARHGEF28,GSTM2,RAB6B,MPP1,RAPGEF2,RPL21,RASA3,RACK1,GUCY1A2,UCHL3,SKAP1,TRIB3,FGR,RPL12,TERT,OSBPL5,MCC,SVIL,PGM2L1,PIP5KL1,HK1,LRRK1,DOCK6,DDIT3,BTRC,TPT1,NUDT17,MVK,FGF13,TRIM16,KIF5A,UGDH,NDRG2,HDGFL3,ASS1,FAM13A,CACNB4,QPRT,GSDME,PLS3,TUBB4A,ARHGEF10L,RPS6KA2,KCNAB1,SEC16B,GRHL1,HPS1,AKAP7,EPHB6,CTTN,ENO1,FANK1,NEB,PRKACB,RASGRP1,KCNIP3,SESN2,SLC3A2,SKAP2,ANK2,ATOX1,NFE2L1,YAP1,PLEKHA1,SGK2,SESN1,GRK3,SERGEF,EML1,TRIM9,AK1,GSN,TCF7L1,GPRC5B,KLF12,MAP2,P4HA2,GNB4,AHNAK2,PIK3C2B,PPARGC1A,CHMP4C,RRAGD,PRKAA2,LONRF1,GPR63,MOCOS,RUNX2,ZNF395,HID1,RHOBTB1,SEC24D,FBXO4,RIMKLA,ATP6V1E2,SETBP1,SORBS3,PHGDH,SPINK5,DOK5,SPIRE1,DDIT4,EEF2,CA2,ZNF354A,RPS11,PDE10A,GAN,ADCY6,CKAP4,NOS3,PAK1,DPYSL5,HBG2,RHOQ,SH2D2A,GSTM4,HOMER2,SPATA13,GPSM1,PPFIA4,WWC1,STRADB,OBSCN,DUSP9,PDE8A,LHPP,AMDHD1,BAIAP2,TBC1D2,MAPKAPK2,ATPAF2,FCHO2,RAB31,RAI14,HK2,FNBP1L,OSBPL6,TESC,SFN,PRKN,SORBS1,AKAP5,DOCK1,IL15,RBFOX2,PSTPIP2,PLEKHA5,ARHGAP22,RHPN2,DENND3,FAM110B,TNKS1BP1,PPP1R9A,DOCK2,CTNNA2,FAM131B,RIDA,IDI1,UNC13B,SETDB2,TACC2,KAZN,PPFIBP1,FABP6,MAP7,FHIT,WWC2,HSPA2,GLI1,CTH,RPS13,GCA,FER,PHLDB2,EVL,TUBA1A,UROS,TDRD3,NOP53,PTPN6,MVD,TES,ACO1,VIM,GSTO1,TTLL7,FRK,DOCK5,WARS,TPK1,SMAD3,RANBP2,LMLN,TRIM34,RNF217,KPNA3,BACH2,GBP1,EIF4EBP1,RGS10,PSPH,TNIK,DYRK3,IL32,ENO2,GRB14,KLHL13,ARHGEF11,RUSC2,REL,BLVRB,MCTP2,NSUN6,IGF2BP2,HBE1,CUEDC2,ARHGAP44,RPL34,SYDE2,TTC1,CHN2,MAP1A,PRKCD,EHD3,TFAP2A,ACTA2,SGK1,AFAP1L2,KLF9,PCK2,IQGAP3,ESD,TNFRSF11A,SYK,CES3,MOB1B,RIN2,RAB3B,KDM5B,NR4A1,CYTH3,LITAF,ASAP3,OGDHL,FERMT2,PRICKLE1,MARS,AGAP2,ARHGAP32,PALLD,FNDC3A,HOMER3,MAP1B,CTIF,SUGT1,DDAH1,ICA1,MAP2K6,SLC7A5,UACA,DLG2,KIF21A,MYRF,RPL4,RPS12,TBC1D4,MAP3K20,NPHP1 |
| 2.607e-02 | -3.65 | V$MAF_Q6 | MSigDB lists | V$MAF_Q6 | 246 | 34 | 17377 | 1707 |
CREB3L2,FGF13,OTX1,SFXN3,SATB1,IKZF2,SP8,FOXP2,PPM1E,KCTD15,HMGCS1,CNTN4,PDZD7,NOVA2,LMAN2,NKX2-1,GAB2,PCDH10,UNC5C,MEIS2,PNRC1,TBC1D8B,ESRRG,AGPAT4,SNAP25,RNF44,NEGR1,SH3RF1,AKT3,ALDOA,SQLE,NXPH4,BMP4,PHC1 |
| 2.607e-02 | -3.65 | V$TATA_01 | MSigDB lists | V$TATA_01 | 246 | 34 | 17377 | 1707 |
RUNX2,RHOBTB1,SCN8A,PLAG1,NDRG2,ATXN7L1,ABLIM1,CA2,EEF2,LHX6,TSC22D1,BNIP3,TSPAN13,SERPINH1,ERRFI1,TSPAN9,ZFP36L2,PDLIM7,MSTN,NR4A1,ESRRG,PANK1,ATOH1,DKK1,KIAA0355,PMEPA1,TMEM117,EGFL7,DIRAS1,TPM1,TNFRSF17,NEUROG2,MID1,AMPD1 |
| 2.608e-02 | -3.65 | regulation of sodium ion transport | biological process | GO:0002028 | 83 | 14 | 17256 | 1658 |
SCN5A,SCN1B,CNKSR3,FGF12,NKAIN2,HECW2,PKP2,ATP1B1,TESC,NEDD4,ATP2B4,STOM,CNTN1,NOS3 |
| 2.608e-02 | -3.65 | regulation of coagulation | biological process | GO:0050818 | 83 | 14 | 17256 | 1658 |
HPSE,UBASH3B,PRKCD,HS3ST5,PRKG1,PRKCQ,ABAT,PROS1,F12,PRKCA,TLR4,SYK,F3,NOS3 |
| 2.619e-02 | -3.64 | ACTTTAT,MIR-142-5P | MSigDB lists | ACTTTAT,MIR-142-5P | 272 | 37 | 17377 | 1707 |
MYO1D,SORBS1,CELSR1,FGF13,BVES,SLC25A27,PLXNA2,NTRK3,EYA4,FAM131B,RTN1,RAB11FIP5,FAM107B,SREBF1,TRIM3,FIGN,TBC1D9,ETV1,LRP12,ATP2B1,MED12L,CHSY3,EIF4E3,RHOQ,COL4A3,RAB6B,SLC36A1,MGAT4B,DCHS1,SHANK2,ATP1B1,ZFPM2,UCHL3,FNDC3A,HERPUD1,FCHO2,NRP1 |
| 2.619e-02 | -3.64 | GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 272 | 37 | 17377 | 1707 |
TNIK,AVPI1,FGF13,NTRK3,GAS6,PKN1,PIBF1,TLR3,PRKCD,GHR,ITGB3,ADCY6,DAB2IP,IQGAP3,TLR4,SYK,PRKACB,TGFA,LRRK2,ADCY1,DUSP9,STRADB,WNT11,PRKAR2B,ACVR2B,TLR6,MAPKAPK2,NRG3,GPRC5B,NCKAP1L,MAP2K6,ERN1,DUSP19,HGF,TNFSF15,BMP4,MAPK10 |
| 2.621e-02 | -3.64 | FGF signaling pathway | Pathway Interaction DB | fgf_pathway | 47 | 11 | 2226 | 278 |
FGFR4,IL17RD,RUNX2,HGF,STAT5B,CTTN,NCAM1,MET,CDH2,SPRY2,FGFR1 |
| 2.624e-02 | -3.64 | GO_SERINE_TYPE_EXOPEPTIDASE_ACTIVITY | MSigDB lists | GO_SERINE_TYPE_EXOPEPTIDASE_ACTIVITY | 18 | 5 | 17377 | 1707 |
CPXM2,PRSS16,CPVL,CPE,PRCP |
| 2.624e-02 | -3.64 | GO_RETINAL_GANGLION_CELL_AXON_GUIDANCE | MSigDB lists | GO_RETINAL_GANGLION_CELL_AXON_GUIDANCE | 18 | 5 | 17377 | 1707 |
SEMA4F,NRP1,EPHB1,ROBO2,SLIT2 |
| 2.624e-02 | -3.64 | REACTOME_SIGNALING_BY_NODAL | MSigDB lists | REACTOME_SIGNALING_BY_NODAL | 18 | 5 | 17377 | 1707 |
SMAD3,ACVR2A,ACVR2B,ACVR1C,PCSK6 |
| 2.624e-02 | -3.64 | GO_GAS_TRANSPORT | MSigDB lists | GO_GAS_TRANSPORT | 18 | 5 | 17377 | 1707 |
HBE1,HBG2,IPCEF1,CA2,MYC |
| 2.624e-02 | -3.64 | GO_SYNTAXIN_1_BINDING | MSigDB lists | GO_SYNTAXIN_1_BINDING | 18 | 5 | 17377 | 1707 |
SNAP25,STXBP1,SYBU,LRRK2,SNPH |
| 2.624e-02 | -3.64 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_2_DN | 18 | 5 | 17377 | 1707 |
GALNT3,EGFL7,SCD,TGFBR3,NCS1 |
| 2.624e-02 | -3.64 | GO_ADRENERGIC_RECEPTOR_BINDING | MSigDB lists | GO_ADRENERGIC_RECEPTOR_BINDING | 18 | 5 | 17377 | 1707 |
PDE4D,MAGI2,RAPGEF2,NEDD4,ADRB1 |
| 2.624e-02 | -3.64 | MODULE_354 | MSigDB lists | MODULE_354 | 18 | 5 | 17377 | 1707 |
CBS,CA2,CA8,ALDH1L1,CTH |
| 2.624e-02 | -3.64 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | MSigDB lists | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | 18 | 5 | 17377 | 1707 |
ACSL1,ELOVL4,ELOVL7,ELOVL3,FASN |
| 2.624e-02 | -3.64 | NELSON_RESPONSE_TO_ANDROGEN_DN | MSigDB lists | NELSON_RESPONSE_TO_ANDROGEN_DN | 18 | 5 | 17377 | 1707 |
SERPINI1,FN1,BCHE,MMP16,MYC |
| 2.625e-02 | -3.64 | SHEPARD_BMYB_MORPHOLINO_DN | MSigDB lists | SHEPARD_BMYB_MORPHOLINO_DN | 195 | 28 | 17377 | 1707 |
PFKFB4,FGFR4,GPT2,RAX,PCDH18,CKAP2,SOX21,BLVRB,MGAT4B,ARID5B,GPSM1,COL4A5,CEBPA,SLX1B,COTL1,EPDR1,SCIN,NSD1,EOMES,CPVL,CDC14B,PRKCB,NOVA2,DLX2,IQGAP3,CEBPD,POU3F3,HEY1 |
| 2.625e-02 | -3.64 | GSE39556_CD8A_DC_VS_NK_CELL_UP | MSigDB lists | GSE39556_CD8A_DC_VS_NK_CELL_UP | 195 | 28 | 17377 | 1707 |
DMXL2,SERINC5,DYRK3,ACSL1,GRB14,PSD3,LCP2,PLCB1,KBTBD11,PFN2,NEDD4,ABLIM1,GYPC,GBP1,TNFRSF1A,KCNS3,LAPTM4B,SERPINI1,GRB10,FHIT,TNFSF4,COBL,ATP2B4,ATP1A3,GAB2,GLDC,CYP1B1,MEF2C |
| 2.625e-02 | -3.64 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | 195 | 28 | 17377 | 1707 |
FADS1,RGS16,LPAR2,COL6A2,ENO2,AASS,SLC39A8,EXOC6B,LDLR,SELL,SMARCD3,UCHL3,DENND3,F3,DDIT4,HOMER3,RAB11FIP5,RTN1,TYMP,MSMO1,ALDOC,PLK2,CTTN,IQSEC2,VGLL4,DHCR7,CEBPD,KCNB2 |
| 2.625e-02 | -3.64 | GO_SKELETAL_SYSTEM_MORPHOGENESIS | MSigDB lists | GO_SKELETAL_SYSTEM_MORPHOGENESIS | 195 | 28 | 17377 | 1707 |
MSX1,INPPL1,RUNX2,BMPR2,NKX3-2,ARID5B,SATB2,ACVR2B,CHSY1,PLEKHA1,BMP6,HOXA1,FGFR1,COL27A1,SKI,SMAD3,INSIG1,WDR19,PCGF2,BMP1,TFAP2A,DLX2,BMP4,SERPINH1,SHOX2,MMP16,SIX2,MEF2C |
| 2.625e-02 | -3.64 | GO_REGULATION_OF_ION_HOMEOSTASIS | MSigDB lists | GO_REGULATION_OF_ION_HOMEOSTASIS | 195 | 28 | 17377 | 1707 |
TRPM4,SCN5A,GSTM2,AKAP5,ANK2,UBASH3B,PTPN6,LRRK2,JPH1,FGF12,RYR2,RASA3,GSTO1,ITPR2,ASPH,SNCA,PTPRC,CXCL10,CA2,SLC30A4,SCN1B,TRPC1,BBC3,PDE4D,BMP4,ATG5,TRPC3,DDIT3 |
| 2.625e-02 | -3.64 | aminoglycan biosynthetic process | biological process | GO:0006023 | 107 | 17 | 17256 | 1658 |
UST,CHSY3,GCNT2,XYLT1,UGDH,SDC3,PXYLP1,CHSY1,BCAN,GPC6,GLCE,HS3ST5,DSEL,HS3ST3B1,PDGFRB,B4GALT7,B4GALT6 |
| 2.626e-02 | -3.64 | regulation of B cell proliferation | biological process | GO:0030888 | 60 | 11 | 17256 | 1658 |
IRS2,PTPRC,VAV3,IKZF3,NCKAP1L,BCL6,TNFSF13B,PRDM1,PKN1,CD40,MEF2C |
| 2.626e-02 | -3.64 | monosaccharide catabolic process | biological process | GO:0046365 | 60 | 11 | 17256 | 1658 |
GAPDH,ENO2,FUT9,PFKFB2,ALDOC,ALDOA,HK2,PGM2L1,HK1,ENO1,CRYL1 |
| 2.628e-02 | -3.64 | GPR35 (G protein-coupled receptor 35) | protein interactions | 2859 | 7 | 3 | 17029 | 1718 |
ATP5IF1,LGALS3,GNAO1 |
| 2.628e-02 | -3.64 | GALT (galactose-1-phosphate uridylyltransferase) | protein interactions | 2592 | 7 | 3 | 17029 | 1718 |
TNK2,TMED9,UBTD2 |
| 2.628e-02 | -3.64 | HABP2 (hyaluronan binding protein 2) | protein interactions | 3026 | 7 | 3 | 17029 | 1718 |
COL4A5,COL4A3,COL4A4 |
| 2.628e-02 | -3.64 | ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5) | protein interactions | 957 | 7 | 3 | 17029 | 1718 |
MXI1,PRKCA,BCHE |
| 2.628e-02 | -3.64 | Amot (angiomotin) | protein interactions | 27494 | 7 | 3 | 17029 | 1718 |
YAP1,AMOTL1,MAP3K21 |
| 2.628e-02 | -3.64 | XIRP1 (xin actin binding repeat containing 1) | protein interactions | 165904 | 7 | 3 | 17029 | 1718 |
ENAH,EVL,NEB |
| 2.628e-02 | -3.64 | SHC4 (SHC adaptor protein 4) | protein interactions | 399694 | 7 | 3 | 17029 | 1718 |
NBEA,CHUK,GAREM1 |
| 2.628e-02 | -3.64 | KCNJ1 (potassium voltage-gated channel subfamily J member 1) | protein interactions | 3758 | 7 | 3 | 17029 | 1718 |
SGK1,SH3RF1,PRKCD |
| 2.628e-02 | -3.64 | Dlg4 (discs large MAGUK scaffold protein 4) | protein interactions | 29495 | 7 | 3 | 17029 | 1718 |
STXBP1,AKAP5,ATP2B4 |
| 2.628e-02 | -3.64 | CRYBG3 (crystallin beta-gamma domain containing 3) | protein interactions | 131544 | 7 | 3 | 17029 | 1718 |
SSH3,PRKAR2B,MLF1 |
| 2.628e-02 | -3.64 | CDC42EP2 (CDC42 effector protein 2) | protein interactions | 10435 | 7 | 3 | 17029 | 1718 |
ARHGAP26,RHOQ,SNCA |
| 2.628e-02 | -3.64 | ROS1 (ROS proto-oncogene 1, receptor tyrosine kinase) | protein interactions | 6098 | 7 | 3 | 17029 | 1718 |
VAV3,PTPN6,ADGRL1 |
| 2.628e-02 | -3.64 | SMR3B (submaxillary gland androgen regulated protein 3B) | protein interactions | 10879 | 7 | 3 | 17029 | 1718 |
BCHE,TNFRSF19,UBTD2 |
| 2.628e-02 | -3.64 | SYT2 (synaptotagmin 2) | protein interactions | 127833 | 7 | 3 | 17029 | 1718 |
NRXN1,KLHL3,STON2 |
| 2.628e-02 | -3.64 | MILR1 (mast cell immunoglobulin like receptor 1) | protein interactions | 284021 | 7 | 3 | 17029 | 1718 |
INPPL1,PTPRD,FHL2 |
| 2.628e-02 | -3.64 | SLC11A2 (solute carrier family 11 member 2) | protein interactions | 4891 | 7 | 3 | 17029 | 1718 |
PRKN,NDFIP2,NEDD4 |
| 2.628e-02 | -3.64 | V$HIF1_Q5 | MSigDB lists | V$HIF1_Q5 | 229 | 32 | 17377 | 1707 |
BCL11B,CCDC126,RGS16,RIMKLA,GRK6,SEZ6L2,IKZF2,PRR7,BMP6,HPCAL4,ZNF827,PPM1E,EIF1,BCL6,KLF9,TMEM132E,ENO1,RWDD2A,MICAL2,GPR176,GAPDH,PRDM13,FGF17,FAM162A,NT5DC2,BCL11A,TSKU,PTPRJ,ENTPD7,NXPH4,P4HA1,MEF2C |
| 2.628e-02 | -3.64 | V$TBP_01 | MSigDB lists | V$TBP_01 | 229 | 32 | 17377 | 1707 |
PRKAA2,RHOBTB1,GABRB2,FZD8,NDRG2,BEX2,NOS1AP,ATXN7L1,GALNT1,ABLIM1,KCTD15,CHRDL1,TSC22D1,TSPAN13,TRPM4,SSH3,ESRRG,NR4A1,PANK1,FHL2,PACSIN3,SMAD3,MSC,GRIK4,KPNA3,PMEPA1,TMEM117,DIRAS1,DLG2,PPARGC1A,TNFRSF17,AMPD1 |
| 2.628e-02 | -3.64 | V$IRF_Q6 | MSigDB lists | V$IRF_Q6 | 229 | 32 | 17377 | 1707 |
KLHL13,ZCCHC24,TNFSF13B,SELL,PRR7,IKZF2,HMCN1,NEDD4,PCDH7,F3,ATXN7L1,EOMES,C15orf41,RBMS2,PDGFRB,ZNF385A,SLC40A1,ITGB7,KCNIP3,MEIS2,MSX1,NAALADL2,GJC1,BCL11A,CXCL10,PLEKHH2,TIFA,TNFSF15,NRP1,SEMA3A,MAPK10,MLLT3 |
| 2.633e-02 | -3.64 | cellular response to leukemia inhibitory factor | biological process | GO:1990830 | 91 | 15 | 17256 | 1658 |
VEGFC,MSC,KDM5B,FZD4,ARID5B,EFHC2,XBP1,HK2,KLF5,PCOLCE2,SNX10,SPRY2,LRAT,GLDC,CTH |
| 2.633e-02 | -3.64 | response to leukemia inhibitory factor | biological process | GO:1990823 | 91 | 15 | 17256 | 1658 |
VEGFC,MSC,KDM5B,FZD4,ARID5B,EFHC2,XBP1,HK2,KLF5,PCOLCE2,SNX10,SPRY2,LRAT,GLDC,CTH |
| 2.633e-02 | -3.64 | activation of GTPase activity | biological process | GO:0090630 | 91 | 15 | 17256 | 1658 |
ADPRHL1,DOCK7,TBC1D8B,TBC1D1,GPR65,RALGAPA2,NTRK3,TBC1D9,TBC1D4,TBC1D16,TBC1D30,RASGRP1,TBC1D8,TBC1D2,SYDE2 |
| 2.635e-02 | -3.64 | ADAM30 (ADAM metallopeptidase domain 30) | protein interactions | 11085 | 12 | 4 | 17029 | 1718 |
CANX,USP30,SEMA6A,PLXNA2 |
| 2.635e-02 | -3.64 | MERTK (MER proto-oncogene, tyrosine kinase) | protein interactions | 10461 | 12 | 4 | 17029 | 1718 |
TNK2,GAS6,BMPR2,SKI |
| 2.635e-02 | -3.64 | EBF1 (early B cell factor 1) | protein interactions | 1879 | 12 | 4 | 17029 | 1718 |
EBF1,ATPAF2,ZNF521,BCL6 |
| 2.635e-02 | -3.64 | PLD6 (phospholipase D family member 6) | protein interactions | 201164 | 12 | 4 | 17029 | 1718 |
KCNC4,SFN,MME,KCNS3 |
| 2.635e-02 | -3.64 | RBM18 (RNA binding motif protein 18) | protein interactions | 92400 | 12 | 4 | 17029 | 1718 |
EPHA3,ACTA2,GSN,TMOD2 |
| 2.646e-02 | -3.63 | T-tubule | cellular component | GO:0030315 | 46 | 9 | 18223 | 1724 |
SCN5A,SCN1B,CACNB2,ANK2,AHNAK2,SCN2A,CACNA2D1,NOS1AP,ATP2B4 |
| 2.646e-02 | -3.63 | apoptotic process | biological process | GO:0006915 | 910 | 105 | 17256 | 1658 |
PDE1B,GRIK2,DOCK1,GPR65,CHAC1,PRKCA,KREMEN1,SEMA6A,STK24,BAG3,EPB41L3,TLR3,PMAIP1,SHF,DAB2IP,HRK,STEAP3,FHIT,PPP2R2B,GULP1,SCN2A,TLR4,SLIT2,PERP,IGFBP3,CYP1B1,PRAME,KCNIP3,ATF4,GAPDH,EVA1A,PDK1,COL4A3,ACVR1C,DCC,PTPN6,BNIP3L,PRKCQ,CD40,SAV1,MAGI3,SNCA,SMAD3,GSN,PRKCB,BEX3,SH3RF1,ERN1,TNFRSF1A,BBC3,TNFSF15,RNF130,ATG5,UNC5B,MEF2C,ROBO2,EDA2R,BMPR2,CKAP2,PAK5,SLK,PLAG1,APBB1,BIK,DHCR24,GAS6,TNFRSF10C,PKN1,SATB1,TNFRSF19,PHLDA2,BEX2,MECOM,DDIT4,BNIP1,MYC,PRKCD,PRELID1,SGK1,BNIP3,TNFRSF11A,ZNF385A,RNF152,PAK1,UNC5C,CARD6,NUAK2,RYR2,HIP1,RACK1,FAM162A,CEBPB,TRIB3,PLAGL1,CECR2,MAP2K6,XBP1,HK2,UACA,TMEM117,BMP4,SEMA3A,KIF1B,DDIT3,SFN |
| 2.649e-02 | -3.63 | stem cell differentiation | biological process | GO:0048863 | 140 | 21 | 17256 | 1658 |
MSX1,GPM6A,ACVR1,RUNX2,SOX21,OVOL2,BATF,EPCAM,PTPRC,EOMES,SEMA4F,BCHE,LRP6,SEMA3C,BMPR1A,NRP1,SEMA3A,SNAI2,FOXA1,FZD1,MEF2C |
| 2.650e-02 | -3.63 | GO_BINDING_BRIDGING | MSigDB lists | GO_BINDING_BRIDGING | 170 | 25 | 17377 | 1707 |
VAV3,SH3BP2,SORBS1,SKAP2,SH2D2A,GRB14,ANK2,EPS8,WWC1,GAS6,SKAP1,DSP,COL14A1,PPP2R3A,BAIAP2,CHN1,CHN2,MPP7,FLRT3,DUSP19,COL19A1,AFAP1L2,DAB2IP,GRB10,GAB2 |
| 2.650e-02 | -3.63 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | 170 | 25 | 17377 | 1707 |
MOB1B,SLC3A2,DYRK3,ACVR1,LGALS3,TMEM65,LRRC8B,UBASH3B,TCEAL3,PHACTR2,ATF3,CHSY1,SNX9,ASPH,TBC1D2,ZSCAN5A,CEBPB,CSF1,SGK1,TNFSF15,GEM,PTPRE,SPRY2,DDIT3,RRAGD |
| 2.650e-02 | -3.63 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN | 170 | 25 | 17377 | 1707 |
RIN2,SLC3A2,GARS,SESN2,COL4A3,ITPRIP,GABRB2,ZNF215,ZBBX,SLC1A3,COLEC10,CD40,DNER,UBTD2,TBC1D30,MCOLN2,GRHL1,SCN1B,TSC22D1,RAI14,POU2F2,SLFN5,ZNF701,IL1RAP,BOD1 |
| 2.652e-02 | -3.63 | double-stranded DNA binding | molecular function | GO:0003690 | 859 | 101 | 17224 | 1680 |
CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,ZNF93,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,ERCC5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,HEY1,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,AFF2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,KDM5B,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 |
| 2.655e-02 | -3.63 | Tyr_Pase_AS | interpro domains | IPR016130 | 74 | 13 | 18492 | 1811 |
PTPRC,SSH3,PTPRJ,DUSP8,PTPRU,CDC14B,PTPRD,PTPN6,PTPN21,PTPRN2,PTPRS,PTPRE,DUSP1 |
| 2.667e-02 | -3.62 | hedgehog receptor activity | molecular function | GO:0008158 | 3 | 2 | 17224 | 1680 |
PTCH2,B9D1 |
| 2.667e-02 | -3.62 | oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor | molecular function | GO:0030614 | 3 | 2 | 17224 | 1680 |
GSTO1,GSTO2 |
| 2.667e-02 | -3.62 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity | molecular function | GO:0030144 | 3 | 2 | 17224 | 1680 |
CCDC126,MGAT5B |
| 2.667e-02 | -3.62 | stretch-activated, cation-selective, calcium channel activity | molecular function | GO:0015275 | 3 | 2 | 17224 | 1680 |
FAM155B,FAM155A |
| 2.667e-02 | -3.62 | fructose-bisphosphate aldolase activity | molecular function | GO:0004332 | 3 | 2 | 17224 | 1680 |
ALDOC,ALDOA |
| 2.667e-02 | -3.62 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor | molecular function | GO:0016672 | 3 | 2 | 17224 | 1680 |
GSTO1,GSTO2 |
| 2.667e-02 | -3.62 | aromatic amino acid transmembrane transporter activity | molecular function | GO:0015173 | 3 | 2 | 17224 | 1680 |
SLC36A4,SLC16A10 |
| 2.667e-02 | -3.62 | microsatellite binding | molecular function | GO:0035939 | 3 | 2 | 17224 | 1680 |
HEYL,HEY1 |
| 2.667e-02 | -3.62 | oxidoreductase activity, acting on phosphorus or arsenic in donors | molecular function | GO:0030613 | 3 | 2 | 17224 | 1680 |
GSTO1,GSTO2 |
| 2.668e-02 | -3.62 | FERM_3 | prosite domains | PS50057 | 48 | 10 | 12060 | 1278 |
FRMPD3,EPB41L5,EPB41L3,PLEKHH2,FARP1,MYO10,PTPN13,PTPN21,TLN2,FRMD5 |
| 2.674e-02 | -3.62 | central_nervous_system-cerebellum-glioma-astrocytoma | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma | 3 | 2 | 17385 | 1698 |
ACVR1,TERT |
| 2.675e-02 | -3.62 | DUF3498 | pfam domains | PF12004 | 3 | 2 | 17054 | 1666 |
DAB2IP,RASAL2 |
| 2.675e-02 | -3.62 | Peptidase_S28 | pfam domains | PF05577 | 3 | 2 | 17054 | 1666 |
PRSS16,PRCP |
| 2.675e-02 | -3.62 | ABM | pfam domains | PF03992 | 3 | 2 | 17054 | 1666 |
NECAB2,NECAB1 |
| 2.675e-02 | -3.62 | BPS | pfam domains | PF08947 | 3 | 2 | 17054 | 1666 |
GRB10,GRB14 |
| 2.675e-02 | -3.62 | JAKMIP_CC3 | pfam domains | PF16034 | 3 | 2 | 17054 | 1666 |
JAKMIP2,JAKMIP3 |
| 2.675e-02 | -3.62 | Glycolytic | pfam domains | PF00274 | 3 | 2 | 17054 | 1666 |
ALDOC,ALDOA |
| 2.675e-02 | -3.62 | Sorb | pfam domains | PF02208 | 3 | 2 | 17054 | 1666 |
SORBS3,SORBS1 |
| 2.675e-02 | -3.62 | PA26 | pfam domains | PF04636 | 3 | 2 | 17054 | 1666 |
SESN2,SESN1 |
| 2.675e-02 | -3.62 | Cu2_monoox_C | pfam domains | PF03712 | 3 | 2 | 17054 | 1666 |
MOXD1,PAM |
| 2.675e-02 | -3.62 | FAM131 | pfam domains | PF15010 | 3 | 2 | 17054 | 1666 |
FAM131C,FAM131B |
| 2.675e-02 | -3.62 | Formyl_trans_C | pfam domains | PF02911 | 3 | 2 | 17054 | 1666 |
ALDH1L2,ALDH1L1 |
| 2.675e-02 | -3.62 | Nucleoplasmin | pfam domains | PF03066 | 3 | 2 | 17054 | 1666 |
NPM1,NPM3 |
| 2.675e-02 | -3.62 | DUF3808 | pfam domains | PF10300 | 3 | 2 | 17054 | 1666 |
TTC39B,TTC39A |
| 2.675e-02 | -3.62 | P4Ha_N | pfam domains | PF08336 | 3 | 2 | 17054 | 1666 |
P4HA1,P4HA2 |
| 2.675e-02 | -3.62 | Popeye | pfam domains | PF04831 | 3 | 2 | 17054 | 1666 |
POPDC3,BVES |
| 2.675e-02 | -3.62 | Cu2_monooxygen | pfam domains | PF01082 | 3 | 2 | 17054 | 1666 |
MOXD1,PAM |
| 2.675e-02 | -3.62 | Latrophilin | pfam domains | PF02354 | 3 | 2 | 17054 | 1666 |
ADGRL2,ADGRL1 |
| 2.675e-02 | -3.62 | DUF1126 | pfam domains | PF06565 | 3 | 2 | 17054 | 1666 |
EFHC1,EFHC2 |
| 2.675e-02 | -3.62 | VASP_tetra | pfam domains | PF08776 | 3 | 2 | 17054 | 1666 |
ENAH,EVL |
| 2.684e-02 | -3.62 | spleen | COSMIC cancer mutations | spleen | 416 | 53 | 17385 | 1698 |
ARHGAP26,TNIK,CCDC148,AMOTL1,SORBS1,ROBO2,PTPRD,CELSR3,KIF5A,NPM1,ADSSL1,DDX60L,COL27A1,FHOD3,TXNRD3,GALNT1,PDZD8,TACC2,GAS2L3,BCL6,LRP6,ADCY6,PLTP,GPR161,PRKACB,CDH26,PCDH10,BCL7A,EIF4E3,MEIS2,SLITRK2,DCDC1,CACNA1E,PARD3B,ANK2,OGDHL,OBSCN,AK4,PHACTR2,SDK1,PRDM1,CRYBG3,EML1,TEX15,FAT4,ITGBL1,PELI2,FAT1,HPGD,HGF,DISP1,THAP10,CACNA2D1 |
| 2.685e-02 | -3.62 | FKBP1B (FK506 binding protein 1B) | protein interactions | 2281 | 30 | 7 | 17029 | 1718 |
RYR2,GSTO1,BMPR1A,ENO2,ENO1,AGL,REL |
| 2.685e-02 | -3.62 | PDE3B (phosphodiesterase 3B) | protein interactions | 5140 | 30 | 7 | 17029 | 1718 |
RNF170,KCNC4,LRRC8B,IL9R,PDGFRB,GNAI1,KCNS3 |
| 2.685e-02 | -3.62 | CYTH2 (cytohesin 2) | protein interactions | 9266 | 30 | 7 | 17029 | 1718 |
CCDC120,INAVA,IPCEF1,ARL4D,PRKCA,PRKCB,SFN |
| 2.685e-02 | -3.62 | DNMBP (dynamin binding protein) | protein interactions | 23268 | 30 | 7 | 17029 | 1718 |
DBN1,ENAH,DNM3,EVL,TUBA1A,WIPF3,NPHP1 |
| 2.685e-02 | -3.62 | GLI3 (GLI family zinc finger 3) | protein interactions | 2737 | 30 | 7 | 17029 | 1718 |
SMAD3,ZIC2,PRKCA,THSD4,BTRC,ZIC1,SKI |
| 2.686e-02 | -3.62 | negative regulation of apoptotic signaling pathway | biological process | GO:2001234 | 217 | 30 | 17256 | 1658 |
PRKN,ACVR1,LGALS3,PAK5,ITGA6,LRRK2,YAP1,STRADB,HERPUD1,EYA4,TERT,SH3RF1,WFS1,XBP1,MAGEA3,PRELID1,SGK3,PCGF2,HGF,CTTN,BMP4,YBX3,UNC5B,NRP1,ENO1,ZNF385A,SNAI2,TPT1,NOS3,CTH |
| 2.688e-02 | -3.62 | Sestrin | interpro domains | IPR006730 | 3 | 2 | 18492 | 1811 |
SESN2,SESN1 |
| 2.688e-02 | -3.62 | PHM/PNGase_F_dom_sf | interpro domains | IPR008977 | 3 | 2 | 18492 | 1811 |
MOXD1,PAM |
| 2.688e-02 | -3.62 | Cat_AA_permease | interpro domains | IPR004755 | 3 | 2 | 18492 | 1811 |
SLC7A1,SLC7A2 |
| 2.688e-02 | -3.62 | BPS-dom | interpro domains | IPR015042 | 3 | 2 | 18492 | 1811 |
GRB10,GRB14 |
| 2.688e-02 | -3.62 | Iml2/TPR_39 | interpro domains | IPR019412 | 3 | 2 | 18492 | 1811 |
TTC39B,TTC39A |
| 2.688e-02 | -3.62 | Cu2_monoox_C | interpro domains | IPR024548 | 3 | 2 | 18492 | 1811 |
MOXD1,PAM |
| 2.688e-02 | -3.62 | FAM131 | interpro domains | IPR026782 | 3 | 2 | 18492 | 1811 |
FAM131C,FAM131B |
| 2.688e-02 | -3.62 | GPCR_2_brain_angio_inhib | interpro domains | IPR008077 | 3 | 2 | 18492 | 1811 |
ADGRB3,ADGRB2 |
| 2.688e-02 | -3.62 | SoHo_dom | interpro domains | IPR003127 | 3 | 2 | 18492 | 1811 |
SORBS3,SORBS1 |
| 2.688e-02 | -3.62 | Enolase-like_superfamily | interpro domains | IPR034390 | 3 | 2 | 18492 | 1811 |
ENO2,ENO1 |
| 2.688e-02 | -3.62 | DUF3498 | interpro domains | IPR021887 | 3 | 2 | 18492 | 1811 |
DAB2IP,RASAL2 |
| 2.688e-02 | -3.62 | DUF1126 | interpro domains | IPR010554 | 3 | 2 | 18492 | 1811 |
EFHC1,EFHC2 |
| 2.688e-02 | -3.62 | MAP1 | interpro domains | IPR026074 | 3 | 2 | 18492 | 1811 |
MAP1A,MAP1B |
| 2.688e-02 | -3.62 | BMP_1/tolloid-like | interpro domains | IPR015446 | 3 | 2 | 18492 | 1811 |
BMP1,TLL2 |
| 2.688e-02 | -3.62 | VASP_sf | interpro domains | IPR038023 | 3 | 2 | 18492 | 1811 |
ENAH,EVL |
| 2.688e-02 | -3.62 | JAKMIP_C | interpro domains | IPR031994 | 3 | 2 | 18492 | 1811 |
JAKMIP2,JAKMIP3 |
| 2.688e-02 | -3.62 | Protein_kinase_C_a/b/g | interpro domains | IPR014375 | 3 | 2 | 18492 | 1811 |
PRKCA,PRKCB |
| 2.688e-02 | -3.62 | GART_AS | interpro domains | IPR001555 | 3 | 2 | 18492 | 1811 |
ALDH1L2,ALDH1L1 |
| 2.688e-02 | -3.62 | Pro_4_hyd_alph_N | interpro domains | IPR013547 | 3 | 2 | 18492 | 1811 |
P4HA1,P4HA2 |
| 2.688e-02 | -3.62 | L_AA_transporter | interpro domains | IPR004760 | 3 | 2 | 18492 | 1811 |
SLC7A11,SLC7A5 |
| 2.688e-02 | -3.62 | Cu2_ascorb_mOase_N_sf | interpro domains | IPR036939 | 3 | 2 | 18492 | 1811 |
MOXD1,PAM |
| 2.688e-02 | -3.62 | Formyl_trans_C_sf | interpro domains | IPR037022 | 3 | 2 | 18492 | 1811 |
ALDH1L2,ALDH1L1 |
| 2.688e-02 | -3.62 | AhpD-like | interpro domains | IPR029032 | 3 | 2 | 18492 | 1811 |
SESN2,SESN1 |
| 2.688e-02 | -3.62 | ABM_dom | interpro domains | IPR007138 | 3 | 2 | 18492 | 1811 |
NECAB2,NECAB1 |
| 2.688e-02 | -3.62 | Enolase_CS | interpro domains | IPR020809 | 3 | 2 | 18492 | 1811 |
ENO2,ENO1 |
| 2.688e-02 | -3.62 | Cu2_ascorb_mOase-like_C | interpro domains | IPR014784 | 3 | 2 | 18492 | 1811 |
MOXD1,PAM |
| 2.688e-02 | -3.62 | Formyl_trans_C | interpro domains | IPR005793 | 3 | 2 | 18492 | 1811 |
ALDH1L2,ALDH1L1 |
| 2.688e-02 | -3.62 | GPCR_2_latrophilin_rcpt_C | interpro domains | IPR003334 | 3 | 2 | 18492 | 1811 |
ADGRL2,ADGRL1 |
| 2.688e-02 | -3.62 | PKN_HR1_1 | interpro domains | IPR037313 | 3 | 2 | 18492 | 1811 |
PKN1,PKN3 |
| 2.688e-02 | -3.62 | Cu2_ascorb_mOase_N | interpro domains | IPR000323 | 3 | 2 | 18492 | 1811 |
MOXD1,PAM |
| 2.688e-02 | -3.62 | Nucleoplasmin | interpro domains | IPR004301 | 3 | 2 | 18492 | 1811 |
NPM1,NPM3 |
| 2.688e-02 | -3.62 | Ribosomal_L24/26_CS | interpro domains | IPR005825 | 3 | 2 | 18492 | 1811 |
RPL26,RPL26L1 |
| 2.688e-02 | -3.62 | Popeye_prot | interpro domains | IPR006916 | 3 | 2 | 18492 | 1811 |
POPDC3,BVES |
| 2.688e-02 | -3.62 | JAKMIP | interpro domains | IPR024836 | 3 | 2 | 18492 | 1811 |
JAKMIP2,JAKMIP3 |
| 2.688e-02 | -3.62 | ZnMP_TLD/BMP1 | interpro domains | IPR034036 | 3 | 2 | 18492 | 1811 |
BMP1,TLL2 |
| 2.688e-02 | -3.62 | Uncharacterised_DM10 | interpro domains | IPR006602 | 3 | 2 | 18492 | 1811 |
EFHC1,EFHC2 |
| 2.688e-02 | -3.62 | PET_prickle | interpro domains | IPR033723 | 3 | 2 | 18492 | 1811 |
PRICKLE1,PRICKLE2 |
| 2.688e-02 | -3.62 | Beta-propeller_rpt_TECPR | interpro domains | IPR006624 | 3 | 2 | 18492 | 1811 |
TECPR1,TECPR2 |
| 2.688e-02 | -3.62 | GPCR_2_latrophilin | interpro domains | IPR003924 | 3 | 2 | 18492 | 1811 |
ADGRL2,ADGRL1 |
| 2.688e-02 | -3.62 | Aldolase_I_AS | interpro domains | IPR029768 | 3 | 2 | 18492 | 1811 |
ALDOC,ALDOA |
| 2.688e-02 | -3.62 | VASP_tetra | interpro domains | IPR014885 | 3 | 2 | 18492 | 1811 |
ENAH,EVL |
| 2.688e-02 | -3.62 | Nucleoplasmin_core_dom | interpro domains | IPR024057 | 3 | 2 | 18492 | 1811 |
NPM1,NPM3 |
| 2.688e-02 | -3.62 | C2_WWC | interpro domains | IPR037771 | 3 | 2 | 18492 | 1811 |
WWC1,WWC2 |
| 2.688e-02 | -3.62 | FBA_I | interpro domains | IPR000741 | 3 | 2 | 18492 | 1811 |
ALDOC,ALDOA |
| 2.688e-02 | -3.62 | Ppantetheine_attach_site | interpro domains | IPR006162 | 3 | 2 | 18492 | 1811 |
ALDH1L2,FASN |
| 2.688e-02 | -3.62 | LIM3_prickle | interpro domains | IPR033727 | 3 | 2 | 18492 | 1811 |
PRICKLE1,PRICKLE2 |
| 2.688e-02 | -3.62 | LIM2_prickle | interpro domains | IPR033726 | 3 | 2 | 18492 | 1811 |
PRICKLE1,PRICKLE2 |
| 2.688e-02 | -3.62 | GlyclTrfase_18 | interpro domains | IPR026116 | 3 | 2 | 18492 | 1811 |
CCDC126,MGAT5B |
| 2.688e-02 | -3.62 | Nucleoplasmin_core_dom_sf | interpro domains | IPR036824 | 3 | 2 | 18492 | 1811 |
NPM1,NPM3 |
| 2.688e-02 | -3.62 | Heavy-metal-associated_CS | interpro domains | IPR017969 | 3 | 2 | 18492 | 1811 |
ATP7B,ATOX1 |
| 2.688e-02 | -3.62 | Peptidase_S28 | interpro domains | IPR008758 | 3 | 2 | 18492 | 1811 |
PRSS16,PRCP |
| 2.689e-02 | -3.62 | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | MSigDB lists | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | 121 | 19 | 17377 | 1707 |
FGFR4,IL17RD,PDE1B,NR4A1,ADCY1,CHUK,STAT5B,PRKAR2B,FGF17,ITPR2,PRKCA,FGFR1,TRIB3,AKT3,PRKCD,ADCY6,SPRY2,PRKACB,GAB2 |
| 2.689e-02 | -3.62 | GO_REGULATION_OF_WOUND_HEALING | MSigDB lists | GO_REGULATION_OF_WOUND_HEALING | 121 | 19 | 17377 | 1707 |
PHLDB2,UBASH3B,PRKCQ,ABAT,F12,PRKCA,F3,HOPX,SMAD3,GSN,HPSE,PRKCD,PRKG1,PROS1,TLR4,TC2N,SYK,HMGCR,NOS3 |
| 2.693e-02 | -3.61 | GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_UP | 187 | 27 | 17377 | 1707 |
MXI1,MARK1,CACNG3,KDM5B,GRIK2,CYB5R2,GALNT6,FHL2,CADM2,ROR1,RGS7,NRXN1,MGMT,FGFR1,SYDE2,ADPRHL1,RND2,TMEM154,ANKRD31,LRRIQ3,MAP7,KLF5,HS3ST3B1,LOXL4,MAGI2,CPE,PCSK6 |
| 2.693e-02 | -3.61 | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 187 | 27 | 17377 | 1707 |
ATL1,MXI1,MVK,GPR65,GJB2,NFIA,RASL11B,COTL1,DSP,RADIL,ILDR2,FHOD3,CD53,DHX32,HTR7,ZNF711,CDR2L,PLAGL1,SLC7A11,BCHE,WWTR1,HK2,ERRFI1,JAKMIP3,MET,NR3C2,KIAA1549 |
| 2.693e-02 | -3.61 | GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_UP | MSigDB lists | GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_UP | 187 | 27 | 17377 | 1707 |
ITGB7,GALNT6,ST6GAL1,RASA3,C1R,COTL1,WDFY4,CD40,KBTBD11,BATF3,HTR7,MSC,SEMA4F,PMEPA1,MCF2L,CPXM2,KIAA1614,GRB10,SH3PXD2B,IPCEF1,LRRK1,TSPAN9,TBC1D4,FOXA1,SMPDL3A,NUDT17,PARP9 |
| 2.693e-02 | -3.61 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | 187 | 27 | 17377 | 1707 |
MOB1B,FADS1,CCDC126,TNIK,ANKRD13D,ALDH2,ADAL,ZHX3,ARHGEF11,ATP8A1,DNAJC6,ABHD13,TTC30A,PRICKLE1,PSD3,SESN1,IKZF2,PFN2,MAGI3,GSN,OTUD1,KPNA3,MPP7,GNB4,TOX,TMEM120B,AMPD1 |
| 2.693e-02 | -3.61 | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN | 187 | 27 | 17377 | 1707 |
PLSCR4,IL32,CFH,IL15,WDR25,AK4,SLC25A28,C1R,SPATS2L,SLC7A2,CD40,PCLO,ATP10D,WARS,HEG1,BATF3,ISG20,CXCL10,TLR3,POU5F1B,PMAIP1,GBP1,HK2,HK1,SP140L,IGFBP3,LAMP3 |
| 2.693e-02 | -3.61 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | 187 | 27 | 17377 | 1707 |
CCDC126,SSH3,LCA5,IGFBP6,MPP1,ALDH1L2,BNIP3L,SELL,RABAC1,ATP10D,WARS,GPLD1,ISG20,FKBP9,SOAT2,HPSE,KPNA3,IGIP,PCBP4,RAP2A,ALG11,PROS1,TSHR,GATM,PURG,SMPDL3A,PARP9 |
| 2.693e-02 | -3.61 | GSE27786_LIN_NEG_VS_NKTCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_NKTCELL_UP | 187 | 27 | 17377 | 1707 |
FADS1,TFCP2L1,ATL1,ALOX5AP,RHOBTB1,SLK,IPO5,CRIP2,YPEL2,AK4,RNF24,SORBS3,CUEDC2,PHGDH,SNX9,SNCA,ATPAF2,GRIK4,KIAA1958,KIAA0895,IDI1,INSIG1,SGK3,OPN3,TUFT1,HK1,GAB2 |
| 2.693e-02 | -3.61 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_UP | 187 | 27 | 17377 | 1707 |
RIN2,PLSCR4,TCP11L2,RNF145,BMPR2,ST6GAL1,YPEL2,OPHN1,PRRG1,CTTNBP2NL,SLC12A6,SNX9,TSPAN17,SPIRE1,RERE,SKI,RAB11FIP5,ID3,RNF180,PDZD8,LAPTM4B,HPGD,LMAN2,MED7,ETV1,ATP2B1,ZNF629 |
| 2.693e-02 | -3.61 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_DN | 187 | 27 | 17377 | 1707 |
SUSD3,CARD6,ARAP2,SORBS1,ID1,KCNQ3,MPP1,GALNT12,PTPN6,LRRK2,TNFAIP8L2,SPATA13,PREX1,CR2,CD40,KIF21B,SLC46A3,SESN1,HOPX,ABLIM1,GSN,GSTO2,RALGPS2,KMO,BCL6,SERPINI1,PTPRE |
| 2.693e-02 | -3.61 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_DN | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_DEC205_CONVERSION_DN | 187 | 27 | 17377 | 1707 |
C2orf88,OPLAH,LANCL3,SIDT1,RNF144A,GRB14,ELOVL7,DNAJC6,PHACTR2,SFXN3,MFSD6,DSP,INPP1,HPCAL4,CRYBG3,TEX15,SEMA4F,EOMES,CFHR1,AKT3,CLDN12,CYP2U1,SLC22A15,PJA1,ZNF518B,CDH2,GLDC |
| 2.693e-02 | -3.61 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | 187 | 27 | 17377 | 1707 |
DMXL2,IL17RD,MICAL2,RUNX2,TTC39B,MYO10,HEBP1,LMCD1,DUSP9,PKP2,PEX5L,LCP2,FRK,SNX9,NAALADL2,STK24,MAPKAPK2,KCNMB4,KIAA0355,PLXDC2,RPS11,STC2,ABI3,SREBF1,SGK1,MED7,JAM2 |
| 2.695e-02 | -3.61 | KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | MSigDB lists | KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | 113 | 18 | 17377 | 1707 |
PLA2G4A,MYLK3,ARHGEF11,ADCY1,CALCRL,PRKCQ,ITPR2,GUCY1A2,PRKCA,PLCB1,KCNMB4,PRKCB,PRKCD,PRKG1,KCNMB3,ADCY6,ACTA2,PRKACB |
| 2.697e-02 | -3.61 | Wnt-protein binding | molecular function | GO:0017147 | 31 | 7 | 17224 | 1680 |
LRP6,ROR1,FZD4,FZD8,WLS,LRP4,FZD1 |
| 2.699e-02 | -3.61 | Gluconeogenesis | REACTOME pathways | R-HSA-70263 | 32 | 7 | 10287 | 971 |
GAPDH,PCK2,ENO2,ENO1,ALDOC,ALDOA,PRKACB |
| 2.704e-02 | -3.61 | phospholipid metabolic process | biological process | GO:0006644 | 423 | 53 | 17256 | 1658 |
PLA2G4A,SERINC5,BTC,MVK,INPPL1,LPCAT2,ISYNA1,LPIN3,ABHD6,ABHD4,INPP1,PGAP1,CDS1,PLPP1,IDI1,HMGCS1,PIK3AP1,SERINC2,FIG4,MET,SMPDL3A,PDGFRB,NKX2-1,FADS1,FGFR4,PLEKHA8,PTPN13,AGPAT4,MVD,GDPD1,PLPP2,PLEKHA1,FGF17,PLCB1,ETNPPL,SMPDL3B,FGFR1,SNCA,GPLD1,IRS2,PLPPR2,ENPP6,PEMT,MFSD2A,OSBPL5,SRD5A3,INPP4B,HGF,PIP5KL1,PIK3C2B,INPP5F,PLD1,MBOAT2 |
| 2.704e-02 | -3.61 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP | 162 | 24 | 17377 | 1707 |
VAV3,ITPRIP,DNAJC3,ITGA6,EFHC2,LILRB1,TTC28,HEG1,TMEM132B,IRS2,ZNF711,BAG3,OTUD1,ARHGAP21,RIMKLB,RASGRF2,PELI2,WDR19,TSC22D1,BMP1,SGK1,ZBTB20,PCSK5,DUSP1 |
| 2.704e-02 | -3.61 | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP | 162 | 24 | 17377 | 1707 |
VNN2,VAV3,LPAR2,ITPRIP,KLHL3,GPR65,ITGA6,YPEL2,RASA3,TRPS1,IRS2,BAG3,FBXO32,RALGPS2,ZFYVE28,PELI2,SGK1,FHIT,VWA5A,SUSD4,DNAH5,FES,PCSK5,DUSP1 |
| 2.707e-02 | -3.61 | GO_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | 59 | 11 | 17377 | 1707 |
BCHE,GRIK2,PLK2,SHANK2,LRRK2,NLGN4X,STXBP1,ABHD6,PPP1R9A,GNAI1,SNCA |
| 2.707e-02 | -3.61 | GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_REGULATION_OF_POTASSIUM_ION_TRANSMEMBRANE_TRANSPORT | 59 | 11 | 17377 | 1707 |
DPP10,KCNIP3,KCNN2,KCNAB1,AKAP7,ANK2,KCNG1,AMIGO1,ATP1B1,NOS1AP,NEDD4 |
| 2.707e-02 | -3.61 | Signaling mediated by p38-gamma and p38-delta | Pathway Interaction DB | p38gammadeltapathway | 10 | 4 | 2226 | 278 |
MAPK13,PKN1,MAP3K20,MAP2K6 |
| 2.712e-02 | -3.61 | GAVIN_FOXP3_TARGETS_CLUSTER_P2 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P2 | 74 | 13 | 17377 | 1707 |
CXCR5,NCKAP1L,RAB6B,PSTPIP2,FOXN3,PRICKLE1,C3orf70,MYO6,CD7,CPE,DSP,SLFN5,LDHD |
| 2.712e-02 | -3.61 | PID_AVB3_INTEGRIN_PATHWAY | MSigDB lists | PID_AVB3_INTEGRIN_PATHWAY | 74 | 13 | 17377 | 1707 |
COL9A3,VAV3,PXN,COL6A2,FN1,IGF1R,COL4A3,COL4A4,CSF1,ITGB3,COL4A5,COL14A1,COL9A2 |
| 2.712e-02 | -3.61 | BAIPRECURSOR | prints domains | PR01694 | 3 | 2 | 4652 | 458 |
ADGRB3,ADGRB2 |
| 2.712e-02 | -3.61 | LATROPHILIN | prints domains | PR01444 | 3 | 2 | 4652 | 458 |
ADGRL2,ADGRL1 |
| 2.712e-02 | -3.61 | ENOLASE | prints domains | PR00148 | 3 | 2 | 4652 | 458 |
ENO2,ENO1 |
| 2.715e-02 | -3.61 | RGS | prosite domains | PS50132 | 35 | 8 | 12060 | 1278 |
RGS17,RGS16,GRK6,RGS7,ARHGEF11,GRK3,RGS10,RGS20 |
| 2.715e-02 | -3.61 | bone-pelvis-chondrosarcoma-peripheral | COSMIC cancer mutations | bone-pelvis-chondrosarcoma-peripheral | 31 | 7 | 17385 | 1698 |
SLC7A1,ACVR2A,SV2B,DSEL,CHN2,UNC5B,DNAH5 |
| 2.718e-02 | -3.61 | Kazal_2 | pfam domains | PF07648 | 31 | 7 | 17054 | 1666 |
SLCO5A1,SLCO4C1,TMEFF2,RECK,SLCO3A1,SPOCK3,FSTL5 |
| 2.729e-02 | -3.60 | Ventricular conduction(PMID:21076409) | GWAS genes | Ventricular conduction(PMID:21076409) | 15 | 6 | 2388 | 399 |
SETBP1,SCN5A,KLF12,PRKCA,CRIM1,NFIA |
| 2.733e-02 | -3.60 | GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_ORGANIC_HYDROXY_COMPOUND_METABOLIC_PROCESS | 468 | 59 | 17377 | 1707 |
PLA2G4A,PRKAA2,NUDT10,INPPL1,MVK,PDE1B,LPCAT2,LDLR,DHCR24,CYP4V2,GATA3,BTBD9,CEBPA,ISYNA1,LPIN3,INPP1,CDS1,CYP51A1,RNF180,IDI1,HMGCS1,SOAT2,MSMO1,BCHE,FABP6,SREBF1,TRPC1,PLTP,SMPDL3A,HMGCR,CYP1B1,ALDH2,EBPL,PFKFB2,SLC27A2,CYB5R2,MVD,VLDLR,NPC2,PLCB1,LRAT,LEPR,SMPDL3B,GPLD1,SNCA,GPR37,INSIG1,ENPP6,ACER2,PEMT,SRD5A3,OSBPL5,INPP4B,SQLE,MAOA,TNFSF4,DHCR7,MBOAT2,ABCG1 |
| 2.733e-02 | -3.60 | Signaling by PDGF | REACTOME pathways | R-HSA-186797 | 376 | 47 | 10287 | 971 |
COL9A3,BTC,PDE1B,FN1,RASAL2,DUSP8,COL4A5,CHUK,STAT5B,ITPR2,PRKCA,PIK3AP1,PRKCD,ITGB3,ADCY6,DAB2IP,NCAM1,MET,COL9A2,GFRA1,RASGRP1,PRKACB,PDGFRB,DUSP1,FGFR4,IL17RD,COL6A2,COL4A3,NR4A1,RAPGEF2,COL4A4,ADCY1,DUSP9,RASA3,AGO4,PRKAR2B,FGF17,FGFR1,IRS2,TRIB3,NRG3,RASGRF2,AKT3,THBS4,GRIN2D,HGF,SPRED3 |
| 2.738e-02 | -3.60 | postsynaptic density membrane | cellular component | GO:0098839 | 32 | 7 | 18223 | 1724 |
PTPRS,GRIN2D,GRIK4,DLG2,CACNG3,GRIK2,GRID1 |
| 2.738e-02 | -3.60 | GO_PROTEINACEOUS_EXTRACELLULAR_MATRIX | MSigDB lists | GO_PROTEINACEOUS_EXTRACELLULAR_MATRIX | 343 | 45 | 17377 | 1707 |
COL9A3,FN1,ITGA6,LAMC3,COL18A1,COL4A5,CHADL,ADAMTS6,SLC1A3,BCAN,COL14A1,HMCN1,COL27A1,EFEMP1,COL22A1,TGFBR3,ABI3BP,FLRT3,FRAS1,COL19A1,COL9A2,SLIT2,ENAM,COL6A2,COL4A3,WISP3,THSD4,COL4A4,WNT11,GSTO1,GPC6,GPLD1,SNCA,ADAMTS17,ADAMTS3,FBN1,CCBE1,THBS4,MATN2,EMILIN2,LAMB1,BMP1,BMP4,SPOCK3,MMP16 |
| 2.742e-02 | -3.60 | IQ_motif_EF-hand-BS | interpro domains | IPR000048 | 82 | 14 | 18492 | 1811 |
MYO1D,IQCH,LRRIQ1,MYO10,SCN8A,RASGRF2,LRRIQ3,MYO1B,MYO3B,OBSCN,IQGAP3,IQSEC2,SCN2A,SCN3A |
| 2.744e-02 | -3.60 | SUSHI | prosite domains | PS50923 | 55 | 11 | 12060 | 1278 |
SUSD3,CD55,CFH,CFHR1,SELL,CR2,C1R,BCAN,SEZ6L2,SUSD4,C4BPB |
| 2.745e-02 | -3.60 | neuron fate commitment | biological process | GO:0048663 | 68 | 12 | 17256 | 1658 |
NKX6-1,BCL11B,GATA2,ZNF521,NTRK3,SATB2,BMP4,ATOH1,DLX2,FOXG1,FOXA1,NKX2-1 |
| 2.752e-02 | -3.59 | actin filament | cellular component | GO:0005884 | 101 | 16 | 18223 | 1724 |
PAK1,GNG12,RHOQ,TMSB15A,MYO1B,FERMT2,PLS1,PALLD,RAC3,PLS3,WIPF3,POF1B,CTTN,MYO6,TPM1,COBL |
| 2.758e-02 | -3.59 | GO_RESPONSE_TO_HORMONE | MSigDB lists | GO_RESPONSE_TO_HORMONE | 873 | 103 | 17377 | 1707 |
PLA2G4A,ACVR1,SORBS1,ACSL1,TRIM16,RBFOX2,GATA3,ASS1,STAT5B,NTRK3,F3,FBXO32,TGFBR3,ASNS,GSTM3,TSHR,SLIT2,PRKACB,PDGFRB,NKX2-1,FZD1,FER,SESN2,PTPRU,ACVR1C,NR6A1,GJB2,ADCY1,PRKAR2B,PRKCQ,ABCC2,GNAI1,IRS2,ENPP1,EIF4EBP1,GNB4,ITGA2,PAM,GRB10,OXTR,TNFSF4,PPARGC1A,NR3C2,PSPH,HEY1,MEF2C,PRKAA2,LATS2,GNG12,INPPL1,ROBO2,FN1,DHCR24,ATP6V1E2,BMP6,NEDD4,NKX6-1,HMGCS1,CA2,IGF1R,EEF2,BCHE,DSG2,PRKCD,GHR,STC2,SREBF1,GRIP1,ADCY6,LRP6,SGK1,KLF9,ERRFI1,AGL,SMAD6,ATP2B1,DUSP1,PAK1,RHOQ,PXN,MSTN,HNF4G,NR4A1,ESRRG,VLDLR,FHL2,LEPR,CPEB1,BAIAP2,GPLD1,MMP15,TRIB3,PMEPA1,FBN1,PLOD2,XBP1,RAB31,BMP4,TBC1D4,SMYD3,FOXA1,ATP1A3,ABCG1 |
| 2.759e-02 | -3.59 | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP | MSigDB lists | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP | 179 | 26 | 17377 | 1707 |
GPT2,PDLIM7,RHOQ,ITPRIP,ITGA6,TNFSF13B,NDRG2,ATF3,ATP1B1,MFSD6,CD40,PLCB1,CPEB1,SLC9A7,CDS1,BCL11A,CEBPB,LMLN,SLC7A11,KCNAB1,PLXDC2,CCNA1,SRD5A3,EPHB6,CKAP4,CYP1B1 |
| 2.759e-02 | -3.59 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | 179 | 26 | 17377 | 1707 |
PXN,ALDH2,RPL21,PPFIBP2,LITAF,KCTD12,PDE8A,STAT5B,CTNNA2,RERE,TRPS1,ISG20,BEX4,DDAH1,BAG3,CPVL,EEF2,MYC,TRIM3,PRKG2,DHRS12,KLF9,IPCEF1,DBP,B4GALT7,DUSP1 |
| 2.759e-02 | -3.59 | GSE2585_CTEC_VS_THYMIC_DC_UP | MSigDB lists | GSE2585_CTEC_VS_THYMIC_DC_UP | 179 | 26 | 17377 | 1707 |
ERGIC1,ST14,SLC36A1,PARD3B,COL4A4,SPATA6,MSR1,PKP2,COL18A1,TTC22,TTLL7,COL27A1,EYA4,TRPS1,SPNS1,NELL2,SLC7A11,MGAT1,ALDH1L1,MYO3B,SFMBT1,PAX9,TANC2,PLTP,COBL,NPHP1 |
| 2.761e-02 | -3.59 | sodium channel activity | molecular function | GO:0005272 | 45 | 9 | 17224 | 1680 |
TRPM4,SCN5A,GRIK4,GRIK2,SCN1B,SCN8A,ASIC1,SCN2A,SCN3A |
| 2.764e-02 | -3.59 | JOHNSTONE_PARVB_TARGETS_2_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_DN | 308 | 41 | 17377 | 1707 |
CCDC126,MYCBP2,BTC,RUNX2,PLEKHA5,RBFOX2,SLK,IPO5,CTBP2,PRKCA,PFN2,UBTD2,RASSF8,ZFYVE28,RUNDC3B,LRP6,LIMCH1,GULP1,FIGN,ESD,CPE,MOB1B,RIN2,GCNT2,TMEM65,SLC39A8,CAP2,MSRB3,SHISA2,SYNJ2BP,ASPH,LEPR,GLCE,AHRR,ENPP1,POPDC3,MAP2,DSEL,HS3ST3B1,SHOX2,DOCK9 |
| 2.765e-02 | -3.59 | LYN (LYN proto-oncogene, Src family tyrosine kinase) | protein interactions | 4067 | 224 | 32 | 17029 | 1718 |
RGS16,CYP4V2,HDGFL3,NDFIP2,LCP2,RBM11,TUBB4A,RASSF8,RNF180,PRKCD,PDE4D,SYK,RIMS2,GAB2,PAK1,TNK2,EVL,SKAP2,PTPN6,PRKCQ,TGDS,KHDRBS2,SKAP1,CENPV,SNCA,PTPRC,PLEKHH2,PRKCB,LRRIQ3,SVIL,OCLN,MME |
| 2.765e-02 | -3.59 | - | gene3d domains | 3.40.1110.10 | 35 | 8 | 8148 | 867 |
ATP11A,ATP9A,ATP10D,ATP8A1,ATP7B,ATP2B1,ATP2B4,ATP1A3 |
| 2.770e-02 | -3.59 | positive regulation of neurological system process | biological process | GO:0031646 | 53 | 10 | 17256 | 1658 |
WASF3,UNC13B,SHANK2,ITGA2,HGF,MYRF,ABAT,NRXN1,RIMS2,BAIAP2 |
| 2.776e-02 | -3.58 | IRS1 (insulin receptor substrate 1) | protein interactions | 3667 | 95 | 16 | 17029 | 1718 |
FER,PTPRU,GRB14,NPM1,CHUK,PRKCQ,NEDD4,IRS2,PTPRC,SMAD3,IGF1R,GHR,PRKCD,GRB10,FES,SFN |
| 2.785e-02 | -3.58 | Heparan sulfate/heparin (HS-GAG) metabolism | REACTOME pathways | R-HSA-1638091 | 54 | 10 | 10287 | 971 |
HPSE,XYLT1,HS3ST5,SDC3,HS3ST3B1,BCAN,GPC6,B4GALT7,GLCE,HS6ST3 |
| 2.786e-02 | -3.58 | Functional MRI(PMID:20215924) | GWAS genes | Functional MRI(PMID:20215924) | 2 | 2 | 2388 | 399 |
KIAA0355,DOK5 |
| 2.786e-02 | -3.58 | Neuroticism(PMID:20634892) | GWAS genes | Neuroticism(PMID:20634892) | 2 | 2 | 2388 | 399 |
NKAIN2,GPC6 |
| 2.786e-02 | -3.58 | Lung cancer(PMID:18385676) | GWAS genes | Lung cancer(PMID:18385676) | 2 | 2 | 2388 | 399 |
HYKK,IL1RAP |
| 2.792e-02 | -3.58 | GROSS_ELK3_TARGETS_DN | MSigDB lists | GROSS_ELK3_TARGETS_DN | 31 | 7 | 17377 | 1707 |
PRKG2,BNIP3,PDK1,HOXB9,FAM162A,VLDLR,CTH |
| 2.792e-02 | -3.58 | GO_POSITIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_EPIDERMIS_DEVELOPMENT | 31 | 7 | 17377 | 1707 |
PTCH2,OVOL2,ATOH1,BMP4,HPSE,TRIM16,SFN |
| 2.792e-02 | -3.58 | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | MSigDB lists | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | 31 | 7 | 17377 | 1707 |
SEMA3C,ID1,IGF1R,FN1,MYC,ITGA6,ITGA2 |
| 2.792e-02 | -3.58 | REACTOME_GLUCONEOGENESIS | MSigDB lists | REACTOME_GLUCONEOGENESIS | 31 | 7 | 17377 | 1707 |
GAPDH,PCK2,ENO2,ENO1,ALDOC,PRKACB,ALDOA |
| 2.792e-02 | -3.58 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_DN | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_G_DN | 31 | 7 | 17377 | 1707 |
FAM171B,DYRK3,RPS6KA2,PCK2,ETV1,GPR19,CPEB1 |
| 2.792e-02 | -3.58 | POS_HISTAMINE_RESPONSE_NETWORK | MSigDB lists | POS_HISTAMINE_RESPONSE_NETWORK | 31 | 7 | 17377 | 1707 |
CEBPB,SLC7A1,ENAH,GARS,ASNS,IL15,PFN2 |
| 2.792e-02 | -3.58 | chr12p11 | MSigDB lists | chr12p11 | 31 | 7 | 17377 | 1707 |
PKP2,PRICKLE1,LRP6,KIF21A,ITPR2,FAR2,DENND5B |
| 2.792e-02 | -3.58 | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP | MSigDB lists | PLASARI_TGFB1_SIGNALING_VIA_NFIC_1HR_UP | 31 | 7 | 17377 | 1707 |
CYP51A1,CALCRL,IDI1,ATF4,KCNAB1,INSIG1,FOXG1 |
| 2.792e-02 | -3.58 | GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 31 | 7 | 17377 | 1707 |
ENPP1,GRB10,PRKCQ,MSTN,PTPRE,PRKCB,PRKCD |
| 2.796e-02 | -3.58 | oligodendroglioma_Grade_III | COSMIC cancer mutations | oligodendroglioma_Grade_III | 310 | 41 | 17385 | 1698 |
OR51B5,EXPH5,MXI1,ROBO2,CELSR1,DOCK1,ARHGEF11,SCN8A,HECW2,CTBP2,CHSY1,PCLO,SLC19A2,HMCN1,COL27A1,NEO1,DNAH6,FUT9,ACVR2A,MYT1,KIAA1549,ZFP36L2,NEB,SEMA6C,RIMS2,PNMA2,MN1,CARD6,RNF145,FGFR1,TMCO3,RIMKLB,VPS37D,TERT,LRRIQ3,LAMB1,UNC5B,TANC2,CTTNBP2,ATP2B4,PCSK5 |
| 2.797e-02 | -3.58 | skin-scalp-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-scalp-carcinoma-squamous_cell_carcinoma | 1632 | 182 | 17385 | 1698 |
MYCBP2,CGN,UGT8,GRIK2,KIF5A,ATP8A1,FHDC1,CHAC1,BCAN,HMCN1,TRPS1,BAG3,CPNE2,ZFYVE28,COL19A1,ATRNL1,TMEM132E,OR2W3,TLR4,DBN1,ITGB7,SLC3A2,COL4A3,SPOCD1,KLHL23,ALDH1L2,CAP2,ANK2,LRRK2,NFE2L1,CR2,ABCC2,KCND3,F12,SGK2,BATF,SPNS1,TMEM132B,ENPP6,MAP2,NCAM2,SEMA3C,PIK3C2B,TMOD2,EFNB2,BCL11B,GPT2,LRFN5,STXBP5L,ZHX3,DHCR24,SETBP1,ZNF215,MECOM,PCDHB14,IL17D,RNF180,NAV1,ZNF354A,FRY,EEF2,CNTN4,ADCK1,BACE2,ZIC5,PRKG1,FAM107B,CPXM2,NCEH1,GLIS1,RIMS2,CAND2,GPR161,CHRM3,NOS3,DPYSL5,RPL26,UNC5C,KCNQ3,COL4A4,VLDLR,HIP1,SHISA2,PEX5L,PLCB1,C4orf19,KHDRBS2,TEX15,PLEKHH2,PKN3,CSF1,MFSD2A,EMILIN2,SH3BP4,DYNC2LI1,CDH17,SEMA3A,MME,SFN,CREB3L2,DMXL2,PLA2G4A,ZSWIM5,CELSR3,PLXNA2,MSR1,ADD2,FAM198B,NRXN1,KIF21B,RADIL,CCDC120,SPEG,COL22A1,ZDHHC6,ZNF521,NAP1L3,MET,DNAH5,HSPA2,GAB2,VNN2,MYLK3,COL6A2,GARS,CYB5R2,KCNH5,PREX1,VIM,SATB2,MAGI3,FGFR1,BCL11A,ARMC4,BACH2,TDO2,ITGA2,ABI3,PTPRS,GRB10,DISP1,HS3ST3B1,PLD5,CNTN1,HACE1,OR51B5,PCDH18,FARP1,WDR17,ROBO2,RUSC2,ATP9A,REL,NLRP14,CCNJL,CLSTN2,GABRG2,COL27A1,MAP1A,LRRN1,SCN1B,KIAA0319,TNFRSF11A,MED12L,CES3,MN1,SYNPO2,AGPAT4,ZDHHC15,PRICKLE1,SMPDL3B,PTPRC,NSD1,TIFA,FAT4,TERT,AKT3,PGM2L1,PIP5KL1,RNF157,KIF1B,ATP1A3 |
| 2.799e-02 | -3.58 | negative regulation of cartilage development | biological process | GO:0061037 | 25 | 6 | 17256 | 1658 |
EFEMP1,CHADL,WNT11,BMP4,NKX3-2,SNAI2 |
| 2.799e-02 | -3.58 | pharyngeal system development | biological process | GO:0060037 | 25 | 6 | 17256 | 1658 |
GATA3,BMPR1A,ACVR1,BMP4,BMPR2,PLXNA2 |
| 2.799e-02 | -3.58 | activin receptor signaling pathway | biological process | GO:0032924 | 25 | 6 | 17256 | 1658 |
SMAD3,ACVR2A,ACVR2B,ACVR1,BMPR2,ACVR1C |
| 2.799e-02 | -3.58 | actin filament polymerization | biological process | GO:0030041 | 25 | 6 | 17256 | 1658 |
COBLL1,WASF3,GSN,CTTN,COBL,PREX1 |
| 2.799e-02 | -3.58 | negative regulation of actin filament bundle assembly | biological process | GO:0032232 | 25 | 6 | 17256 | 1658 |
ARHGAP28,PRKN,PHLDB2,MET,TMEFF2,PPP1R9A |
| 2.802e-02 | -3.57 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 146 | 22 | 17377 | 1707 |
ATF4,PDK1,EDA2R,CHAC1,STK24,DDIT4,CEBPB,TRIB3,PMAIP1,ERN1,PRKCD,XBP1,TNFRSF1A,BBC3,DAB2IP,BNIP3,FHIT,SCN2A,DDIT3,PERP,SFN,CYP1B1 |
| 2.804e-02 | -3.57 | STEIN_ESR1_TARGETS | MSigDB lists | STEIN_ESR1_TARGETS | 82 | 14 | 17377 | 1707 |
PNRC1,CHRNA5,SLC27A2,CAP2,SLC39A8,RAB26,RAI14,RAB31,FHL2,SGK1,ABAT,SUSD4,RAB27B,ABCG1 |
| 2.809e-02 | -3.57 | PID_PTP1B_PATHWAY | MSigDB lists | PID_PTP1B_PATHWAY | 52 | 10 | 17377 | 1707 |
FER,FGR,CSN2,CSF1,ITGB3,STAT5B,CDH2,LEPR,SPRY2,PDGFRB |
| 2.810e-02 | -3.57 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_UP | 514 | 64 | 17377 | 1707 |
CXCR5,DNM3,ELOVL4,PDE1B,RECK,DNAJC3,PTPN21,PPFIBP2,KCTD12,CHAC1,BCAN,COL14A1,TXNRD3,TLR3,ABI3BP,BCL6,VWA5A,RCAN3,PDGFRB,LAMP3,GCA,PHLDB2,ATF4,COL4A3,DCC,JPH1,SYNJ2BP,CXCL10,TRIM34,PLK2,ERN1,HOXB9,LIFR,SLC9B1,EFNB2,SLC6A9,NECAB2,TBC1D1,PHLDA2,MYC,GHR,SGK1,CEBPD,FES,RIMS2,HMGCR,PARP9,RIN2,ARAP2,PNP,C1R,PRDM1,FNDC3A,STEAP1,CEBPB,TIFA,PLAGL1,FBN1,RND3,PMEPA1,NACC2,CSF1,PCGF2,CMPK2 |
| 2.810e-02 | -3.57 | determination of left/right symmetry | biological process | GO:0007368 | 116 | 18 | 17256 | 1658 |
MICAL2,ACVR1,NKX3-2,OVOL2,ACVR2B,SMAD3,ARMC4,SETDB2,LRRC6,DYNC2LI1,TBC1D32,ACVR2A,DISP1,DYNC2H1,DNAH5,MEF2C,PCSK5,PCSK6 |
| 2.818e-02 | -3.57 | MIKKELSEN_NPC_HCP_WITH_H3K27ME3 | MSigDB lists | MIKKELSEN_NPC_HCP_WITH_H3K27ME3 | 326 | 43 | 17377 | 1707 |
LRFN5,SCN5A,CELSR1,SYT12,CLSTN2,GALNT13,OVOL2,FOXG1,COL14A1,BMP6,HPCAL4,PHLDA2,SP8,CYP26A1,NKX6-1,SERINC2,KCNS3,NPTXR,TMEM132E,SLCO4C1,GFI1,TNFRSF11A,SLIT2,DOCK8,PGBD5,NKX2-1,DPP10,EIF4E3,GJB2,RYR2,TCERG1L,SKAP1,LRAT,BCL11A,GPR37,HTR7,MSC,IKZF3,BMP4,HOXB9,COBL,MAST1,ABCG1 |
| 2.820e-02 | -3.57 | GO_KINASE_BINDING | MSigDB lists | GO_KINASE_BINDING | 587 | 72 | 17377 | 1707 |
AKAP5,RHOD,DNAJC3,RGS20,PKP2,NPM1,CEBPA,MAPK4,CACNB4,PPP1R9A,NCS1,SKI,NELL2,AKAP7,DACT1,NBEA,JAKMIP2,DAB2IP,MARCKS,WWC2,JAKMIP3,PDGFRB,GAB2,PFKFB2,ANK2,PTPN6,FEZ1,PRKAR2B,DSP,SMAD3,IRS2,CAMK2N1,NRG3,PTPRJ,GPRC5B,PRKCB,DUSP19,PAM,DIRAS1,SCN5A,LRP4,SLC12A6,GAS6,PKN1,EEF2,CACNB2,GHR,PRKCD,SREBF1,ADCY6,SGK1,ACTA2,ERRFI1,STXBP1,SPRY2,SYK,MOB1B,PAK1,PXN,WWC1,RYR2,SKAP1,CEBPB,PTPRC,TRIB3,FGR,MAP2K6,XBP1,DLG2,CDH2,PKIA,SFN |
| 2.820e-02 | -3.57 | Signaling by Activin | REACTOME pathways | R-HSA-1502540 | 13 | 4 | 10287 | 971 |
SMAD3,ACVR2A,ACVR2B,ACVR1C |
| 2.820e-02 | -3.57 | Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels | REACTOME pathways | R-HSA-112308 | 13 | 4 | 10287 | 971 |
CACNB4,CACNA1E,CACNB2,CACNA2D1 |
| 2.824e-02 | -3.57 | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_UP | 171 | 25 | 17377 | 1707 |
SUSD3,MAN2B2,VNN2,ITGB7,ITPRIP,GALNT12,UBASH3B,EFHC2,TCEA3,NPC2,GABARAPL1,IRS2,ZNF438,SLC22A18,PELI2,ALDOC,SCRN1,ZBTB20,FHIT,SUSD4,RNF157,FES,LPP,DUSP1,CRYL1 |
| 2.824e-02 | -3.57 | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP | 171 | 25 | 17377 | 1707 |
QSOX1,GNG12,TES,LPCAT2,RAPGEF2,MYO1B,PPFIBP2,KCTD12,PRKAR2B,IGF2BP2,CD40,SLCO3A1,HERPUD1,DCBLD2,HEG1,CEBPB,SLC39A14,PDE10A,ZDHHC6,HK2,PRELID1,MET,RAPGEF5,RAB30,LPP |
| 2.824e-02 | -3.57 | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 171 | 25 | 17377 | 1707 |
BCL11B,LRFN5,MVK,SORBS1,TBC1D1,ATP9A,VAMP8,KIAA1324L,RNF125,HERC5,SATB2,SHISA2,GAS6,ATP1B1,IKZF2,MKX,ZNF93,SEMA4F,AKAP7,TFAP2A,HS3ST5,RCAN3,COL9A2,C15orf41,SNX7 |
| 2.827e-02 | -3.57 | ZNRF4 (zinc and ring finger 4) | protein interactions | 148066 | 80 | 14 | 17029 | 1718 |
DAGLA,BNIP1,PDZD8,PTPRU,KCNG1,ERN1,ADGRL1,SQLE,ADCY6,ACVR2B,SLC12A6,ITPR2,CANX,LRP12 |
| 2.828e-02 | -3.57 | morphogenesis of an epithelium | biological process | GO:0002009 | 415 | 52 | 17256 | 1658 |
ACVR1,CELSR1,LGR4,ST14,OPHN1,GATA3,OVOL2,DDR1,SKI,SETDB2,CA2,FLRT3,FRAS1,MYC,RAP2A,TFAP2A,LRP6,MET,SPRY2,SLIT2,PRKACB,FZD1,NKX2-1,INTU,PAK1,EPB41L5,VEGFC,MICAL2,KDM5B,KLHL3,DCHS1,RYR2,YAP1,PRICKLE1,WNT11,FGFR1,SMAD3,FAT4,PTK7,CSF1,CTSV,SEMA3C,HOXD13,BMP4,TMEFF2,NRP1,SEMA3A,COBL,FOXA1,BTRC,SIX2,MEF2C |
| 2.831e-02 | -3.56 | GO_ORGANELLE_SUBCOMPARTMENT | MSigDB lists | GO_ORGANELLE_SUBCOMPARTMENT | 291 | 39 | 17377 | 1707 |
PCSK1N,SCAMP1,ATP9A,ATP8A1,LPCAT2,ST6GAL1,BACE1,MYO1B,RGS20,CHAC1,CHSY1,SNX9,SLC9A7,GALNT1,FUT9,NBEA,COG3,CLVS2,RAB27B,B4GALT6,CHSY3,ATL1,PLEKHA8,WLS,LRRK2,CBY1,SNAP25,RAB38,B4GALNT3,ASPH,GALNT3,ICA1,ATP7B,RAB31,PAM,FNBP1L,B4GALT7,RAB30,HACE1 |
| 2.837e-02 | -3.56 | 6-blade_b-propeller_TolB-like | interpro domains | IPR011042 | 38 | 8 | 18492 | 1811 |
TENM1,TRIM2,LRP4,VLDLR,LDLR,PAM,LRP6,TRIM3 |
| 2.837e-02 | -3.56 | V$PBX1_01 | MSigDB lists | V$PBX1_01 | 239 | 33 | 17377 | 1707 |
PHACTR3,SLC6A9,FGF13,RBFOX2,SLK,COL4A5,PRDM8,ADAMTS6,STAT5B,ZIC2,CBLN1,PRRG4,PCDH7,KCTD15,SMTN,PRICKLE2,BEND4,MYT1,PCDH10,BDNF,COL4A3,HNF4G,NR6A1,COL4A4,PRDM13,EDEM3,FEZ1,ZFPM2,ZIC1,ZNF711,PTPRC,DLG2,HOXB9 |
| 2.840e-02 | -3.56 | positive regulation of cell morphogenesis involved in differentiation | biological process | GO:0010770 | 141 | 21 | 17256 | 1658 |
PAK1,BDNF,FN1,BMPR2,ROBO2,PTPRD,DOCK1,PREX1,PLXNA2,NTRK3,AMIGO1,DOCK5,RAC3,BAIAP2,MAP1B,RND2,MYADM,NRP1,SHOX2,SLIT2,SHTN1 |
| 2.844e-02 | -3.56 | GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_DN | 138 | 21 | 17377 | 1707 |
ARHGAP26,TMEM67,GCNT2,PLSCR4,LGALS3,SCN8A,UBASH3B,ARL15,EPS8,ADAMTS6,ZBBX,NDFIP2,IL18R1,GABARAPL1,PIK3AP1,ERN1,MYOM2,FIG4,STON2,ATP2B1,PERP |
| 2.844e-02 | -3.56 | BMI1_DN_MEL18_DN.V1_UP | MSigDB lists | BMI1_DN_MEL18_DN.V1_UP | 138 | 21 | 17377 | 1707 |
VEGFC,PAGE1,SLC6A9,ADM2,RUSC2,VLDLR,ATF3,KIF21B,ASPH,F3,TRIB3,SLC7A11,PMEPA1,FAM189A1,CSF1,STC2,SLC7A5,INHBE,MARCH3,TUFT1,GAB2 |
| 2.845e-02 | -3.56 | ER-mitochondrion membrane contact site | cellular component | GO:0044233 | 13 | 4 | 18223 | 1724 |
RAB38,PDZD8,ATG5,CANX |
| 2.845e-02 | -3.56 | mitotic spindle midzone | cellular component | GO:1990023 | 13 | 4 | 18223 | 1724 |
CTTN,MAP9,EML1,MAP10 |
| 2.846e-02 | -3.56 | ERBIN (erbb2 interacting protein) | protein interactions | 55914 | 103 | 17 | 17029 | 1718 |
DBN1,ABCC4,MPP1,CHUK,ACVR2B,GUCY1A2,ZFYVE9,SMAD3,MYC,LAMB1,MCC,MPP2,ACVR2A,BTRC,ATP2B1,ATP2B4,CTNND2 |
| 2.847e-02 | -3.56 | BMPER (BMP binding endothelial regulator) | protein interactions | 168667 | 3 | 2 | 17029 | 1718 |
BMP4,BMP6 |
| 2.847e-02 | -3.56 | Tjp1 (tight junction protein 1) | protein interactions | 21872 | 3 | 2 | 17029 | 1718 |
CGN,OCLN |
| 2.847e-02 | -3.56 | SPOCK2 (SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2) | protein interactions | 9806 | 3 | 2 | 17029 | 1718 |
TES,SPOCK3 |
| 2.847e-02 | -3.56 | SEMA3A (semaphorin 3A) | protein interactions | 10371 | 3 | 2 | 17029 | 1718 |
KCND3,NRP1 |
| 2.847e-02 | -3.56 | HAMP (hepcidin antimicrobial peptide) | protein interactions | 57817 | 3 | 2 | 17029 | 1718 |
SLC40A1,CKAP4 |
| 2.847e-02 | -3.56 | Mycbp2 (MYC binding protein 2, E3 ubiquitin protein ligase) | protein interactions | 290447 | 3 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 2.847e-02 | -3.56 | FAM57A (family with sequence similarity 57 member A) | protein interactions | 79850 | 3 | 2 | 17029 | 1718 |
MAPK4,SLC3A2 |
| 2.847e-02 | -3.56 | DUSP15 (dual specificity phosphatase 15) | protein interactions | 128853 | 3 | 2 | 17029 | 1718 |
IGF1R,PTK7 |
| 2.847e-02 | -3.56 | PTPRCAP (protein tyrosine phosphatase, receptor type C associated protein) | protein interactions | 5790 | 3 | 2 | 17029 | 1718 |
PTPRC,FN1 |
| 2.847e-02 | -3.56 | Dlg1 (discs large MAGUK scaffold protein 1) | protein interactions | 25252 | 3 | 2 | 17029 | 1718 |
AKAP5,ATP2B4 |
| 2.847e-02 | -3.56 | 1810055G02Rik (RIKEN cDNA 1810055G02 gene) | protein interactions | 72056 | 3 | 2 | 17029 | 1718 |
TPM1,RAI14 |
| 2.847e-02 | -3.56 | DSCAML1 (DS cell adhesion molecule like 1) | protein interactions | 57453 | 3 | 2 | 17029 | 1718 |
MAGI2,MAGI3 |
| 2.847e-02 | -3.56 | SSPO (SCO-spondin) | protein interactions | 23145 | 3 | 2 | 17029 | 1718 |
ATXN7L1,TTC28 |
| 2.847e-02 | -3.56 | SLC6A12 (solute carrier family 6 member 12) | protein interactions | 6539 | 3 | 2 | 17029 | 1718 |
LIN7A,REL |
| 2.847e-02 | -3.56 | Map4 (microtubule-associated protein 4) | protein interactions | 17758 | 3 | 2 | 17029 | 1718 |
MARK1,SNCA |
| 2.847e-02 | -3.56 | XDH (xanthine dehydrogenase) | protein interactions | 7498 | 3 | 2 | 17029 | 1718 |
CCDC110,MYC |
| 2.847e-02 | -3.56 | Snca (synuclein, alpha) | protein interactions | 20617 | 3 | 2 | 17029 | 1718 |
NEDD4,SNCA |
| 2.847e-02 | -3.56 | Act5C (Actin 5C) | protein interactions | 31521 | 3 | 2 | 17029 | 1718 |
LRRK2,RERE |
| 2.847e-02 | -3.56 | Rab14 (RAB14, member RAS oncogene family) | protein interactions | 68365 | 3 | 2 | 17029 | 1718 |
TBC1D4,TBC1D1 |
| 2.847e-02 | -3.56 | MRVI1 (murine retrovirus integration site 1 homolog) | protein interactions | 10335 | 3 | 2 | 17029 | 1718 |
MME,PRKG1 |
| 2.847e-02 | -3.56 | Tubb5 (tubulin, beta 5 class I) | protein interactions | 29214 | 3 | 2 | 17029 | 1718 |
PRICKLE1,PRICKLE2 |
| 2.847e-02 | -3.56 | MIA (melanoma inhibitory activity) | protein interactions | 8190 | 3 | 2 | 17029 | 1718 |
BAG3,FN1 |
| 2.847e-02 | -3.56 | TNFAIP8L2 (TNF alpha induced protein 8 like 2) | protein interactions | 79626 | 3 | 2 | 17029 | 1718 |
TES,AHNAK2 |
| 2.848e-02 | -3.56 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 | MSigDB lists | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A12 | 265 | 36 | 17377 | 1707 |
DMXL2,COL9A3,STXBP6,ST6GAL1,LDLR,ZNF215,SPATS2L,SEL1L3,ZFYVE9,FKBP11,KCNJ4,GATA2,ZNF440,RAP2A,RAB26,TFAP2A,CTTN,SH3BP2,RHOQ,PDK1,OGDHL,FGF12,TTC30A,PRDM1,RABAC1,SKAP1,HERPUD1,ISG20,TMCO3,XBP1,NXPH4,TNFRSF17,LZTS1,SLC43A1,MAST1,DENND5B |
| 2.860e-02 | -3.55 | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | 188 | 27 | 17377 | 1707 |
FADS1,LANCL3,GALNT6,ESRP1,ATOX1,MEF2B,SHISA2,SCD,SGK2,BMP6,KREMEN1,SPATA7,IRS2,GPR15,RNF180,CA2,UNC13B,PLXDC2,EIF1,GAN,NBEA,HS3ST3B1,FIG4,ESD,CTH,CRYL1,FZD1 |
| 2.860e-02 | -3.55 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_UP | 188 | 27 | 17377 | 1707 |
WASF3,LGR4,GCAT,KLHL23,CKAP2,STAT4,GATA3,TDRKH,SNAP25,LCP2,SKAP1,CPEB1,PLEKHB1,ISG20,ICA1,KCNMB4,GYPC,BCHE,ITGBL1,C1orf21,INPP4B,LAPTM4B,TSPAN13,GFI1,GFRA1,SLIT2,RASGRP1 |
| 2.860e-02 | -3.55 | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | MSigDB lists | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | 188 | 27 | 17377 | 1707 |
PAK1,QSOX1,MICAL2,RGS16,ACVR1,ACSL1,EHHADH,SKAP2,ZHX3,COL4A4,MGST3,XYLT1,VLDLR,VAMP8,GATA3,CHRNA6,GSTO1,ATP1B1,BATF,SATB1,SLC39A14,TM9SF2,PLOD2,BMP4,IL1RAP,PKIA,ATP2B1 |
| 2.860e-02 | -3.55 | GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN | MSigDB lists | GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN | 188 | 27 | 17377 | 1707 |
PRKAA2,DPYSL5,SYNPO2,MYLK3,BVES,KLHL13,CAP2,ESRRG,CRIP2,TCEA3,RYR2,PPP2R3A,SYDE2,DKK1,ADPRHL1,CAMK2N1,RGS17,GNAO1,CLDN12,PRKG1,EBF4,LIN7A,LIMCH1,PPARGC1A,MBOAT2,DOCK6,PCSK6 |
| 2.860e-02 | -3.55 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN | 188 | 27 | 17377 | 1707 |
PDK1,IL32,TMEM65,SFXN4,SLC39A8,ARID5B,IPO5,ADD2,FAM102B,BATF,SNTB1,NDFIP2,TAF4B,LCP2,CD7,SLC7A1,DACT1,MYC,CSF1,SLC7A5,SREBF1,BCL6,RAB27B,RNF157,ENO1,RAB30,ATP2B4 |
| 2.860e-02 | -3.55 | GSE5589_WT_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | 188 | 27 | 17377 | 1707 |
PRKAA2,GPR63,NBL1,EDA2R,ZHX3,DSTN,CRIP2,LRRCC1,SLITRK5,EFHC1,ATP1B1,MFSD6,DSP,LGI2,SIPA1L2,CDR2L,AK1,PPFIA2,CECR2,GNAO1,GRIP1,ADCY6,MORN2,KIF21A,MYO6,RCAN3,SEPT3 |
| 2.860e-02 | -3.55 | GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN | 188 | 27 | 17377 | 1707 |
LONRF1,ACSL1,ATF4,TTC39B,PSTPIP2,JDP2,UBASH3B,ARHGAP22,PLXNA2,ATF3,SLC7A2,GPC6,SMPDL3B,HERPUD1,F3,CEBPB,KPNA3,CSF1,FLRT3,SLC2A6,GEM,CMPK2,MET,PTPRE,SLC16A10,RAB30,DUSP1 |
| 2.860e-02 | -3.55 | GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | 188 | 27 | 17377 | 1707 |
ATL1,TUBA1A,PFKFB2,SFXN4,AGPAT4,LDLR,MEF2B,GPR180,COTL1,DENND3,PGAP1,HOPX,CAMK2N1,RTN1,GSN,ABCA5,CNKSR3,GPR155,ZDHHC23,ATRNL1,TSPAN13,ERCC5,MYO6,RCAN3,DENND1C,CRYL1,SNX7 |
| 2.860e-02 | -3.55 | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | 188 | 27 | 17377 | 1707 |
RGS16,FARP1,SKAP2,ST14,JDP2,GPR65,UBASH3B,CYTH3,LITAF,PHACTR2,AMIGO1,NDFIP2,TEX9,SNX9,EPDR1,ISG20,EPCAM,ICA1,TACC2,STARD4,INPP4B,MED7,IPCEF1,IQGAP3,GFI1,FILIP1,PERP |
| 2.860e-02 | -3.55 | GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_UP | MSigDB lists | GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_UP | 188 | 27 | 17377 | 1707 |
CARD6,USP2,ANKRD13D,PLXNA2,KIF5C,MAFB,ACVR2B,FAM198B,KIAA1217,GDPD5,FAM110B,EYA4,MTUS1,SKI,RNF180,ZFYVE28,GPR155,RPS11,GAS2L3,WDR19,TMEM86A,SGK1,MED7,FIG4,WWC2,LRRC27,LIFR |
| 2.860e-02 | -3.55 | ABI3 (ABI family member 3) | protein interactions | 51225 | 37 | 8 | 17029 | 1718 |
PAK1,MAGEA12,EVL,ABI3BP,ABI3,KIAA0408,ENAH,HOMER3 |
| 2.860e-02 | -3.55 | HEPACAM2 (HEPACAM family member 2) | protein interactions | 253012 | 37 | 8 | 17029 | 1718 |
LGR4,ERO1B,ACVR2A,PTPRS,BMPR1A,ACVR2B,FGFR1,HMGCR |
| 2.860e-02 | -3.55 | TMOD1 (tropomodulin 1) | protein interactions | 7111 | 37 | 8 | 17029 | 1718 |
PRKAA2,DBN1,PDLIM7,GSN,TBC1D4,NEB,WARS,SCIN |
| 2.860e-02 | -3.55 | PSG8 (pregnancy specific beta-1-glycoprotein 8) | protein interactions | 440533 | 37 | 8 | 17029 | 1718 |
FAT4,CELSR3,RHOBTB1,FAT1,FRAS1,VWDE,LAMB1,CPE |
| 2.862e-02 | -3.55 | regulation of peptide secretion | biological process | GO:0002791 | 452 | 56 | 17256 | 1658 |
EXPH5,PRKN,FN1,C1QTNF3,STXBP5L,LGR4,TRIM16,APBB1,ARL2,LILRB1,GATA3,CHUK,ITPR2,GAS6,ABAT,NRXN1,PRKCA,BMP6,MCU,NKX6-1,RAB11FIP5,UNC13B,SREBF1,KCNS3,MARCKS,PCK2,MYRIP,TLR4,SYK,IL1RAP,RASGRP1,HMGCR,TRPM4,VEGFC,GAPDH,PFKFB2,ACVR1C,WLS,CACNA1E,SYBU,LRRK2,RAPGEF4,SNAP25,CD40,TLR6,SERGEF,GPLD1,IRS2,FGR,ICA1,GBP1,XBP1,PAM,DISP1,ATG5,TNFSF4 |
| 2.863e-02 | -3.55 | regulation of dendrite morphogenesis | biological process | GO:0048814 | 84 | 14 | 17256 | 1658 |
TNIK,LZTS3,DNM3,ID1,ADGRB3,PTPRD,RAPGEF2,LRRK2,RAP2A,HECW2,PPP1R9A,NEDD4,ARHGAP44,BAIAP2 |
| 2.865e-02 | -3.55 | C1QB (complement C1q B chain) | protein interactions | 713 | 24 | 6 | 17029 | 1718 |
COLGALT2,C1R,IL32,FN1,EDA2R,USP30 |
| 2.865e-02 | -3.55 | ARHGAP26 (Rho GTPase activating protein 26) | protein interactions | 23092 | 24 | 6 | 17029 | 1718 |
RAB11FIP5,PKN1,NRXN1,PKN3,JPH1,OPHN1 |
| 2.865e-02 | -3.55 | ROBO2 (roundabout guidance receptor 2) | protein interactions | 6092 | 24 | 6 | 17029 | 1718 |
MYCBP2,CPE,NR4A1,SLIT2,MYC,BNIP3L |
| 2.865e-02 | -3.55 | BMP4 (bone morphogenetic protein 4) | protein interactions | 652 | 24 | 6 | 17029 | 1718 |
PROS1,BMPR1A,BMP4,BMPR2,ZFYVE9,CHRDL1 |
| 2.865e-02 | -3.55 | GO_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY | MSigDB lists | GO_PHOSPHORIC_DIESTER_HYDROLASE_ACTIVITY | 90 | 15 | 17377 | 1707 |
ENPP1,PDE1B,ENPP6,PDE10A,GDPD1,PDE8A,NOTUM,PLD1,PDE4D,PLCB1,GDPD5,SMPDL3B,SMPDL3A,CHRM3,GPLD1 |
| 2.865e-02 | -3.55 | GO_BASEMENT_MEMBRANE | MSigDB lists | GO_BASEMENT_MEMBRANE | 90 | 15 | 17377 | 1707 |
EFEMP1,FN1,COL4A3,FBN1,COL4A4,THBS4,FRAS1,ITGA6,MATN2,LAMB1,LAMC3,COL18A1,GSTO1,COL4A5,HMCN1 |
| 2.865e-02 | -3.55 | chr10q24 | MSigDB lists | chr10q24 | 90 | 15 | 17377 | 1707 |
MXI1,AVPI1,PDZD7,PIK3AP1,NPM3,ELOVL3,ADRB1,ABCC2,SLC25A28,CHUK,CUEDC2,LOXL4,SFXN3,MORN4,BTRC |
| 2.871e-02 | -3.55 | MIKKELSEN_ES_ICP_WITH_H3K4ME3 | MSigDB lists | MIKKELSEN_ES_ICP_WITH_H3K4ME3 | 661 | 80 | 17377 | 1707 |
TBKBP1,TRIM2,ADAL,TCTN2,TRIM16,IL15,AASS,FAM198B,NRXN1,FAM13A,QPRT,ADPRHL1,TLR3,AADAT,AKAP7,SLC22A18,ALDOC,ALDH1L1,MDH1B,ETV1,ITGB7,TMEM67,ADM2,ANK2,CYB5R2,C3orf52,LRMP,PANK1,ZNF565,RNF125,C9orf116,PYCR1,ENTPD1,AK1,INHBC,ABI3,PLEKHG1,DUSP19,RCN3,FAM149A,SERPINI1,LIFR,SLC9B1,C8orf48,TMEM63C,LPAR2,EHHADH,ZNF395,NSUN6,PRSS35,COL4A5,SLC12A6,SFXN3,ATXN7L1,FLRT3,KIAA0408,PTPRCAP,FKBP14,RBMS2,PAK1,RIN2,OPLAH,AGPAT4,GSTM4,STAT4,MBNL2,LDHD,FGR,TMEM154,PRCP,RAI14,DYNC2LI1,INHBE,SPRED3,SEMA3A,PTGES,CRISPLD1,ZNF235,DOCK9,PHC1 |
| 2.874e-02 | -3.55 | Canonical and Non-Canonical TGF-B signaling | WikiPathways | WP3874 | 17 | 5 | 5312 | 569 |
SMAD3,BMPR1A,LOXL4,BMPR2,BMP1 |
| 2.875e-02 | -3.55 | GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL | MSigDB lists | GO_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE_MEDIATED_BY_A_CHEMICAL_SIGNAL | 45 | 9 | 17377 | 1707 |
RPS6KA2,ADRB1,PDE4D,OXTR,TPM1,MME,PCSK5,NKX2-1,NOS3 |
| 2.875e-02 | -3.55 | CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_INTERFERON_DN | 45 | 9 | 17377 | 1707 |
EXPH5,FADS1,HLF,BTNL9,CDC14B,GRB10,TNFRSF19,MME,SLC16A10 |
| 2.875e-02 | -3.55 | GO_REGULATION_OF_PHAGOCYTOSIS | MSigDB lists | GO_REGULATION_OF_PHAGOCYTOSIS | 67 | 12 | 17377 | 1707 |
FGR,NCKAP1L,GATA2,C4A,ITGA2,LMAN2,GAS6,PLD1,PROS1,DOCK2,SYK,C4BPB |
| 2.875e-02 | -3.55 | HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_DN | MSigDB lists | HOSHIDA_LIVER_CANCER_LATE_RECURRENCE_DN | 67 | 12 | 17377 | 1707 |
ENPP1,CHRNA5,PEMT,CDH17,MAOA,COBLL1,NAP1L3,APBA1,PHGDH,SPINK5,PKIA,MME |
| 2.877e-02 | -3.55 | viral entry into host cell | biological process | GO:0046718 | 92 | 15 | 17256 | 1658 |
EFNB2,GPR15,TYRO3,ITGB7,CD55,KPNA3,LDLR,VAMP8,ITGA2,ITGB3,CR2,GAS6,NCAM1,SLC1A5,LAMP3 |
| 2.878e-02 | -3.55 | GSE11818_WT_VS_DICER_KO_TREG_UP | MSigDB lists | GSE11818_WT_VS_DICER_KO_TREG_UP | 130 | 20 | 17377 | 1707 |
SERINC5,GSTM2,DUSP8,CLGN,RASA3,SATB2,ZIC2,RAB38,KCND3,RAC3,PHLDA2,FSTL5,EPCAM,ADPRHL1,KCNJ4,SCN1B,PCGF2,SCARF2,AMPD1,NKX2-1 |
| 2.882e-02 | -3.55 | ZHAN_MULTIPLE_MYELOMA_HP_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_HP_UP | 38 | 8 | 17377 | 1707 |
PAK1,SIDT1,ELOVL7,GTF2F2,CCDC85A,EPHB1,RPL13A,LAMP3 |
| 2.882e-02 | -3.55 | GGCAGAC,MIR-346 | MSigDB lists | GGCAGAC,MIR-346 | 38 | 8 | 17377 | 1707 |
SMAD3,KCTD15,AFF2,BCL6,PRICKLE2,LRP6,FAM155B,PFN2 |
| 2.882e-02 | -3.55 | GO_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION | MSigDB lists | GO_PEPTIDYL_TYROSINE_AUTOPHOSPHORYLATION | 38 | 8 | 17377 | 1707 |
TNK2,FER,FGR,IGF1R,FRK,DDR1,SYK,FES |
| 2.882e-02 | -3.55 | HAHTOLA_SEZARY_SYNDROM_DN | MSigDB lists | HAHTOLA_SEZARY_SYNDROM_DN | 38 | 8 | 17377 | 1707 |
NELL2,VAV3,BACH2,TSPAN13,NCAM1,SESN1,APBA2,HOPX |
| 2.882e-02 | -3.55 | GO_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | MSigDB lists | GO_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | 38 | 8 | 17377 | 1707 |
CACNG3,CACNB2,CACNA1E,PDE4D,CACNB4,HSPA2,CACNA2D1,NOS1AP |
| 2.882e-02 | -3.55 | LIN_MELANOMA_COPY_NUMBER_DN | MSigDB lists | LIN_MELANOMA_COPY_NUMBER_DN | 38 | 8 | 17377 | 1707 |
MYCBP2,FNDC3A,KPNA3,ESD,CLN5,RPL21,TPT1,CRYL1 |
| 2.882e-02 | -3.55 | chr18q12 | MSigDB lists | chr18q12 | 38 | 8 | 17377 | 1707 |
MOCOS,GALNT1,PSTPIP2,DSG2,RNF125,MAPK4,CDH2,FHOD3 |
| 2.883e-02 | -3.55 | regulation of protein complex assembly | biological process | GO:0043254 | 443 | 55 | 17256 | 1658 |
TENM1,TMSB15A,STXBP6,EPS8,BIK,ARL2,JCHAIN,ADD2,SNX9,PFN2,RAC3,PPP1R9A,RPL13A,FHOD3,SPIRE1,SCIN,TUBB4A,UNC13B,PMAIP1,DACT1,PRKCD,GTF2F2,DAB2IP,HRK,CTTN,MET,SMAD6,TLR4,STXBP1,SLIT2,FES,PAK1,FER,EVL,NOP53,PREX1,RACK1,TLR6,BAIAP2,SNCA,WARS,DKK1,TRIM9,GSN,MYADM,INSIG1,WIPF3,PMEPA1,MPP7,NCKAP1L,MAP2,CDH17,ARHGAP28,TMOD2,ERCC5 |
| 2.887e-02 | -3.55 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_UP | 163 | 24 | 17377 | 1707 |
CARD6,SLC37A1,FGF13,PTPN6,CYTH3,RAPGEF4,PRRG1,PRKCQ,GABRR2,ATP1B1,SATB1,KBTBD11,ABLIM1,TGFBR3,TERT,ATRNL1,MARCH3,INPP5F,PACSIN1,TBC1D4,TESC,MLLT3,CAND2,SNAI2 |
| 2.901e-02 | -3.54 | GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS | MSigDB lists | GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS | 98 | 16 | 17377 | 1707 |
PFKFB4,NMNAT3,GAPDH,PNP,ENO2,PFKFB2,OGDHL,NUDT12,QPRT,KMO,ALDOC,ALDOA,HK2,HK1,ENO1,HMGCR |
| 2.901e-02 | -3.54 | GO_GLYCOPROTEIN_BINDING | MSigDB lists | GO_GLYCOPROTEIN_BINDING | 98 | 16 | 17377 | 1707 |
CFH,VLDLR,LDLR,LRRK2,VIM,CANX,GPC6,FGFR1,MAP2,BBC3,LMAN2,BMPR1A,FBXO27,SLIT2,CNTN1,ATP1A3 |
| 2.903e-02 | -3.54 | GO_OSTEOBLAST_DIFFERENTIATION | MSigDB lists | GO_OSTEOBLAST_DIFFERENTIATION | 122 | 19 | 17377 | 1707 |
MRC2,RUNX2,LGR4,FASN,FHL2,SATB2,WNT11,BMP6,SMAD3,RPS11,WWTR1,BMP4,RRAS2,SHOX2,SNAI2,MEF2C,FZD1,GLI1,IGFBP3 |
| 2.903e-02 | -3.54 | Serine biosynthesis, glycerate-3P => serine | KEGG pathways | hsa_M00020 | 3 | 2 | 7161 | 730 |
PHGDH,PSPH |
| 2.903e-02 | -3.54 | Serine biosynthesis, glycerate-3P => serine | KEGG pathways | M00020 | 3 | 2 | 7161 | 730 |
PHGDH,PSPH |
| 2.903e-02 | -3.54 | TUBB (tubulin beta class I) | protein interactions | 203068 | 267 | 37 | 17029 | 1718 |
PRKN,INPPL1,FN1,LGR4,BMPR2,UBASH3B,ARL2,TJP1,PKN1,STK24,SKI,TUBB4A,MAP1A,EEF2,MYC,GAN,NCAM1,ERRFI1,SYK,GDAP1,DISC1,MID2,GAPDH,TUBA1A,TES,LRRK2,YAP1,SDC3,AGO4,RACK1,EML1,SNCA,RANBP2,ALDOA,NPHP1,MID1,HEY1 |
| 2.908e-02 | -3.54 | TNFR_NGFR_1 | prosite domains | PS00652 | 23 | 6 | 12060 | 1278 |
TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A |
| 2.910e-02 | -3.54 | AGTPBP1 (ATP/GTP binding protein 1) | protein interactions | 23287 | 18 | 5 | 17029 | 1718 |
PPFIA4,DISC1,TNIK,CBY1,ENO1 |
| 2.910e-02 | -3.54 | RGS14 (regulator of G protein signaling 14) | protein interactions | 10636 | 18 | 5 | 17029 | 1718 |
RND2,RND3,GNAO1,RAP2A,GNAI1 |
| 2.910e-02 | -3.54 | BDNF (brain derived neurotrophic factor) | protein interactions | 627 | 18 | 5 | 17029 | 1718 |
BDNF,CADPS2,NCAM1,CPE,NOS3 |
| 2.914e-02 | -3.54 | bone-pelvis-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-pelvis-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 656 | 79 | 17385 | 1698 |
SORBS1,CELSR3,PSTPIP2,CHAC1,KIAA1217,SEZ6L2,RADIL,CCNJ,TRPS1,GPR15,RNF150,TACC2,REEP1,RTKN2,MYH15,SLC2A12,PCOLCE2,PROS1,PTPRE,MYT1,NTNG1,DOCK8,DCC,PTPN6,ANK2,LRRK2,NFE2L1,CHRNA6,TNS1,ATP1B1,ACVR2B,RNF44,SERGEF,BCL11A,ZNF266,PLK2,ALDOA,PIK3C2B,PLD5,CTTNBP2,ANKRD13D,WDR17,INPPL1,SLC6A9,TSPAN15,PTPRD,NSUN6,OPHN1,PHGDH,COL27A1,NEDD4,KIAA1958,CA2,MAP1A,EEF2,BCHE,CACNB2,RUNDC3B,MYO6,ATP2B1,CKAP4,CES3,HMGCR,VLDLR,KIAA1324L,SDC3,OBSCN,SDK1,ZBBX,ZFPM2,PALLD,MYADM,KIAA0355,CSF1,FAT1,THSD7B,PTGES,NPHP1,ACSM3 |
| 2.916e-02 | -3.53 | regulation of endocytosis | biological process | GO:0030100 | 236 | 32 | 17256 | 1658 |
EPHA3,TNK2,NECAB2,LGALS3,C4A,LDLR,LRRK2,DNAJC6,OPHN1,PACSIN3,LILRB1,HIP1,BTBD9,GAS6,RACK1,SYNJ2BP,DOCK2,C4BPB,SNCA,DKK1,FGR,SH3GL2,NCKAP1L,GATA2,APELA,ITGA2,LMAN2,ATG5,PACSIN1,MAGI2,SYK,STON2 |
| 2.917e-02 | -3.53 | GO_NEPHRON_DEVELOPMENT | MSigDB lists | GO_NEPHRON_DEVELOPMENT | 114 | 18 | 17377 | 1707 |
LGR4,COL4A3,KLHL3,COL4A4,DCHS1,GATA3,WNT11,FAT4,MYC,HEYL,WWTR1,ACTA2,BMP4,MAGI2,POU3F3,PDGFRB,SIX2,MEF2C |
| 2.917e-02 | -3.53 | CCP | smart domains | SM00032 | 53 | 11 | 9493 | 1056 |
SUSD3,CD55,CFH,CFHR1,SELL,CR2,C1R,BCAN,SEZ6L2,SUSD4,C4BPB |
| 2.917e-02 | -3.53 | GO_ION_CHANNEL_BINDING | MSigDB lists | GO_ION_CHANNEL_BINDING | 106 | 17 | 17377 | 1707 |
SCN5A,KCNIP3,FGF13,KCNH5,ANK2,LRRK2,FGF12,PKP2,RYR2,KCND3,ASPH,PPP1R9A,HERPUD1,KCNAB1,TRPC1,PDE4D,RIMS2 |
| 2.917e-02 | -3.53 | ATGCAGT,MIR-217 | MSigDB lists | ATGCAGT,MIR-217 | 106 | 17 | 17377 | 1707 |
RIN2,GPM6A,ELOVL4,FN1,GRIK2,KCNH5,NFIA,TMTC4,STAT5B,ATP1B1,NOVA1,BCL11A,ZNF711,CHN2,KLF12,TACC2,ACVR2A |
| 2.917e-02 | -3.53 | GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_COLUMNAR_CUBOIDAL_EPITHELIAL_CELL_DIFFERENTIATION | 106 | 17 | 17377 | 1707 |
B9D1,NKX3-2,MCOLN3,WNT11,PRDM1,ATOH1,SAV1,BMP6,FGFR1,PLS3,NKX6-1,PDZD7,KLF5,BMP4,CDH2,FOXA1,MEF2C |
| 2.919e-02 | -3.53 | MODULE_3 | MSigDB lists | MODULE_3 | 380 | 49 | 17377 | 1707 |
GNG12,FN1,ITGA6,LDLR,SFXN3,NHP2,RAC3,PHLDA2,MTUS1,PLS3,EFEMP1,EPB41L3,GALNT1,MSMO1,SMTN,SGK1,SERPINH1,SEMA6C,PDLIM7,DBN1,FADS1,QSOX1,MICAL2,CD55,PNP,CRIM1,MYO10,FHL2,CALCRL,FERMT2,CCNG1,STEAP1,FGFR1,HOMER3,SMAD3,INSIG1,PLOD2,RND3,PLK2,EIF4EBP1,WWTR1,LAMB1,SLC7A5,SQLE,BMP4,TPM1,SLC1A5,CDH2,PKIA |
| 2.920e-02 | -3.53 | TAGLN (transgelin) | protein interactions | 6876 | 51 | 10 | 17029 | 1718 |
BAG3,ENO2,EEF2,ALDOC,ALDOA,PRKCD,GSTO1,UCHL3,ENO1,PLS3 |
| 2.920e-02 | -3.53 | SDC1 (syndecan 1) | protein interactions | 6382 | 51 | 10 | 17029 | 1718 |
BAG3,FARP1,HMGCS1,GNB4,RAP2A,EEPD1,HGF,NCAM1,OCLN,CTH |
| 2.924e-02 | -3.53 | GO_VESICLE_MEDIATED_TRANSPORT | MSigDB lists | GO_VESICLE_MEDIATED_TRANSPORT | 1148 | 132 | 17377 | 1707 |
EXPH5,DOC2A,PRSS12,SYT12,KIF5A,ATP8A1,LDLR,VAMP8,LILRB1,SYT14,DNER,SNX9,PCDH7,TXNDC5,SEC16B,ITGB3,RAB26,LIN7A,TMED9,CTTN,COG3,PACSIN1,RASGRP1,TNK2,CD55,ERGIC1,ABCC4,ANK2,EXOC6B,TGFA,LRRK2,DNAJC6,LRMP,TRIM9,GSN,ENPP1,NCKAP1L,WIPF3,ALDOA,INPP5F,TC2N,CHMP4C,TYRO3,INPPL1,MRC2,FN1,STXBP5L,BVES,SEC24D,STXBP6,OPHN1,MLC1,DYNC1I1,SPIRE1,BNIP1,GATA2,LRP6,LMAN2,CADPS2,LOXL4,STXBP1,LRP3,RIMS2,LRP12,SNX7,PAK1,QSOX1,MYO10,VLDLR,RAPGEF4,PACSIN3,CALCRL,HIP1,SNAP25,BAIAP2,MAPKAPK2,VPS37D,SH3GL2,FCHO2,MFSD2A,CECR2,SH3BP4,RAB31,DYNC2LI1,FNBP1L,CREB3L2,DNM3,SCAMP1,DOCK1,MYO1B,MSR1,CANX,PCLO,DOCK2,ZFYVE9,SCIN,UNC13B,SCRN1,PROS1,GULP1,RAB27B,SNX10,RARRES2,SNCA,HGF,SEPT5,STON2,MYO1D,ATP9A,LRP4,GAS6,NEDD4,ARHGAP44,RAB11FIP5,EHD3,GHR,PRKCD,MARCH3,DYNC2H1,MYO6,SYK,VEGFC,PDLIM7,RIN2,VAV3,RAB6B,CYTH3,PHACTR2,FGR,OSBPL5,TBC1D4,SNPH |
| 2.927e-02 | -3.53 | ARMC1 (armadillo repeat containing 1) | protein interactions | 55156 | 44 | 9 | 17029 | 1718 |
DPYSL5,GPM6A,GARS,MAP2,GNAO1,EPS8,NCAM1,STXBP1,CNTN1 |
| 2.927e-02 | -3.53 | CD83 (CD83 molecule) | protein interactions | 9308 | 44 | 9 | 17029 | 1718 |
MYADM,BMPR2,PTPRD,DAB2IP,STEAP3,GRK6,BMPR1A,SLC7A2,RADIL |
| 2.927e-02 | -3.53 | DFFA (DNA fragmentation factor subunit alpha) | protein interactions | 1676 | 44 | 9 | 17029 | 1718 |
NAP1L5,PRKAA2,GAPDH,NECAB2,TUBA1A,GNB4,MCC,FERMT2,SEPT5 |
| 2.927e-02 | -3.53 | LITAF (lipopolysaccharide induced TNF factor) | protein interactions | 9516 | 44 | 9 | 17029 | 1718 |
CARS,BAG3,PTPRD,HECW2,BMPR1A,RADIL,HPCAL4,FGFR1,NEDD4 |
| 2.929e-02 | -3.53 | plasma membrane receptor complex | cellular component | GO:0098802 | 178 | 25 | 18223 | 1724 |
ITGB7,ACVR1,SORBS1,CACNG3,ACVR1C,GRIK2,PTPN6,ITGA6,SHANK2,CALCRL,CHRNA6,CHUK,IL13RA1,CD40,SKAP1,ABHD6,TLR6,GRIK4,CHRNA5,ITGA2,ITGB3,GRIN2D,DLG2,BMPR1A,SYK |
| 2.929e-02 | -3.53 | V$GATA1_04 | MSigDB lists | V$GATA1_04 | 231 | 32 | 17377 | 1707 |
ENO2,CHCHD7,PLAG1,MSR1,NDRG2,CREB5,TNFRSF19,BMP6,EYA4,PPP2R3A,PCDH7,MECOM,TRPS1,FOXP2,RALGPS2,SAMD11,PRELID1,NDUFA4L2,SLITRK2,TMEM65,HNF4G,FZD4,ANK2,MBNL2,ZIC1,HTR7,CEBPB,ID3,KLF12,ZBTB20,HOXB9,PKIA |
| 2.931e-02 | -3.53 | axon terminus | cellular component | GO:0043679 | 110 | 17 | 18223 | 1724 |
KCNIP3,GRIK2,PRSS12,BLVRB,LRRK2,OPHN1,ROR1,KCNC4,PFN2,SNCA,UNC13B,FLRT3,ITGA2,RGS10,PTPRN2,PACSIN1,CHRM3 |
| 2.934e-02 | -3.53 | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | MSigDB lists | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | 180 | 26 | 17377 | 1707 |
ACSL1,ELOVL4,TUBA1A,FN1,EML6,SLC27A2,SFXN4,RAPGEF2,C3orf52,EPS8,NRN1,PLS1,PRDM1,RABAC1,SPATS2L,DNER,TTC30B,PRRG4,CENPV,ISM1,PRKCD,SFMBT1,SH3BGRL2,ATG5,SYNGR3,PERP |
| 2.934e-02 | -3.53 | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_UP | 180 | 26 | 17377 | 1707 |
BDNF,FGF13,KCNH5,RIMKLA,LITAF,DSP,HOXA1,ARHGEF26,CAMK2N1,INHBC,TEX15,ENPP1,IKZF3,ITGB3,MAP7,ACVR2A,MYOM2,KIF21A,PROS1,NCEH1,MYO6,PPARGC1A,VASH2,CMPK2,RASGRP1,C3orf67 |
| 2.934e-02 | -3.53 | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP | 180 | 26 | 17377 | 1707 |
MPZL3,SLC40A1,MVK,DYRK3,MYO10,MVD,GPSM1,RYR2,ADD2,NDRG2,IGF2BP2,GAS6,TBC1D16,TPD52L1,PCLO,CTNNA2,HEG1,IQCH,NRG3,RNF217,NACC2,CFHR1,ATP7B,NBEA,SERPINH1,RNF148 |
| 2.935e-02 | -3.53 | non_functioning | COSMIC cancer mutations | non_functioning | 241 | 33 | 17385 | 1698 |
DOC2A,EDA2R,MSR1,FAM13A,RGS7,TNKS1BP1,PCDHB14,MCOLN2,COL22A1,GRHL1,JAKMIP2,MYH15,MET,ZNF391,COL4A3,ABCC4,SPOCD1,DCC,TRAM1L1,FASN,OBSCN,ZNF558,JAM3,PYCR1,MAP1B,PTPRJ,ENPP6,TERT,NXPH4,SEMA3C,ZNF808,TANC2,DOCK9 |
| 2.939e-02 | -3.53 | MECP2 and Associated Rett Syndrome | WikiPathways | WP3584 | 62 | 12 | 5312 | 569 |
BDNF,GPRIN1,DLX6,MPP1,GRID1,BCL6,SGK1,GABRR2,MYT1,CEBPD,ARHGEF26,MEF2C |
| 2.946e-02 | -3.52 | GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_DN | MSigDB lists | GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_DN | 155 | 23 | 17377 | 1707 |
FRMPD3,DPYSL5,PNP,PTPN13,ATF7IP2,CADM2,TMEM170B,AMDHD1,HMCN1,GPLD1,CECR2,AFF2,ANKFN1,FABP6,TIGD4,BDH2,CNNM2,SERPINI1,FIG4,PLD5,SPRY4,FAM84B,IGFBP3 |
| 2.946e-02 | -3.52 | GSE4984_UNTREATED_VS_GALECTIN1_TREATED_DC_DN | MSigDB lists | GSE4984_UNTREATED_VS_GALECTIN1_TREATED_DC_DN | 155 | 23 | 17377 | 1707 |
CXCR5,SUSD3,BCL7A,RPL21,IPO5,ATF7IP2,CR2,SEL1L3,DDR1,CENPV,ID3,ABLIM1,NELL2,BACH2,RALGPS2,PMEPA1,PIK3C2B,TSPAN13,CYP2U1,TNFRSF17,SCN3A,SLC16A10,DENND5B |
| 2.946e-02 | -3.52 | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP | MSigDB lists | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP | 155 | 23 | 17377 | 1707 |
CXCR5,DPP10,EML5,OPLAH,MRC2,CRIM1,AIG1,SDK1,MGAT5B,SNX9,HECTD2,QPRT,MCOLN2,KCNMB4,PMEPA1,PRKCB,WFS1,INPP4B,TOX,PACSIN1,TANC2,NTNG1,SLC43A1 |
| 2.950e-02 | -3.52 | positive regulation of smoothened signaling pathway | biological process | GO:0045880 | 32 | 7 | 17256 | 1658 |
INTU,CHSY1,DISP1,DYNC2H1,SHOX2,FOXA1,GLI1 |
| 2.950e-02 | -3.52 | regulation of vascular endothelial growth factor receptor signaling pathway | biological process | GO:0030947 | 32 | 7 | 17256 | 1658 |
VEGFC,DAB2IP,GRB10,PRKCB,FZD4,NEDD4,ITGB3 |
| 2.950e-02 | -3.52 | response to iron ion | biological process | GO:0010039 | 32 | 7 | 17256 | 1658 |
SLC40A1,ABAT,BMP6,APBB1,SNCA,TFAP2A,ACO1 |
| 2.950e-02 | -3.52 | salivary gland development | biological process | GO:0007431 | 32 | 7 | 17256 | 1658 |
TFCP2L1,SEMA3C,EDA,NRP1,SEMA3A,FGFR1,XBP1 |
| 2.950e-02 | -3.52 | olfactory bulb development | biological process | GO:0021772 | 32 | 7 | 17256 | 1658 |
DLX2,EOMES,ROBO2,SEMA3A,SLIT2,LRRK2,SKI |
| 2.961e-02 | -3.52 | regulation of autophagy of mitochondrion | biological process | GO:1903146 | 39 | 8 | 17256 | 1658 |
PRKN,ATP5IF1,SREBF1,BNIP3L,HK2,BNIP3,CTTN,USP30 |
| 2.961e-02 | -3.52 | cell-substrate junction assembly | biological process | GO:0007044 | 39 | 8 | 17256 | 1658 |
FERMT2,TNS1,SORBS1,CTTN,FN1,RHOD,ITGA6,ITGA2 |
| 2.965e-02 | -3.52 | CACGTG_V$MYC_Q2 | MSigDB lists | CACGTG_V$MYC_Q2 | 960 | 112 | 17377 | 1707 |
PLA2G4A,CCDC126,CGN,AVPI1,FLVCR2,CELSR3,ASS1,NPM1,CEBPA,CTBP2,GRK6,SEZ6L2,NRXN1,CANX,PRR7,NUP62CL,EYA4,FKBP11,ADPRHL1,KCTD15,KCNAB1,COL25A1,TMEM86A,BCL6,MAP7,BEND4,PPP2R2B,TMEM132E,ETV1,GAPDH,ATF4,ABCC4,RNF145,NR6A1,JPH1,ZNF565,TCEAL3,SATB2,ACVR2B,TMEM47,RNF44,METAP1D,TSKU,BATF3,SPNS1,DYRK1B,ZNF711,IKZF3,LMLN,ENPP6,ALDOA,B3GALT2,DLX2,ATG5,PPARGC1A,RAB30,BCL11B,FARP1,RUNX2,WDR17,ANKRD13B,PLAG1,ST6GAL1,CMTM8,ARL2,SLC12A6,PKN1,BMP6,BEX2,HPCAL4,ARHGAP44,RPL13A,MTUS1,IGF1R,ADCK1,BHLHA15,RPS11,RASD2,STC2,PRELID1,TRIM3,SGK1,SLC6A15,KLF9,SEPT3,DUSP1,GPR176,MICAL2,BDNF,USP2,SLC36A1,VLDLR,SYBU,DCHS1,OGDHL,GUCY1A2,ARRDC4,HOXA1,HERPUD1,ZIC1,CTIF,ADAMTS17,CEBPB,PLAGL1,ADAMTS3,SLC7A5,RAB31,SLCO5A1,BMP4,PANK3,DIRC2,SLC43A1 |
| 2.982e-02 | -3.51 | GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | MSigDB lists | GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 543 | 67 | 17377 | 1707 |
ACVR1,ST14,RGS20,PLXNA2,GATA3,CEBPA,KIAA1217,SKI,EOMES,DACT1,ACVR2A,ENO1,PRKACB,FZD1,INTU,NKX3-2,SATB2,WNT11,RARRES2,FGFR1,SMAD3,PTK7,SEMA3C,DLX2,BMPR1A,TANC2,TPM1,APBA2,HOXB9,COBL,MEF2C,PCSK5,HEY1,LATS2,RUNX2,CELSR1,SEC24D,TJP1,OVOL2,APBA1,PHGDH,PPP2R3A,HOPX,GATA2,MGAT1,TFAP2A,LRP6,NOS3,EPB41L5,B9D1,MSX1,DCHS1,PRICKLE1,PRDM1,ZFPM2,HOXA1,HEG1,DKK1,CEBPB,CECR2,WDR19,PCGF2,BMP4,SHOX2,MMP16,SIX2,FOXA1 |
| 2.984e-02 | -3.51 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin | KEGG pathways | ko00534 | 24 | 6 | 7161 | 730 |
HS3ST3B1,B4GALT7,XYLT1,GLCE,HS3ST5,HS6ST3 |
| 2.984e-02 | -3.51 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin | KEGG pathways | hsa00534 | 24 | 6 | 7161 | 730 |
HS3ST3B1,XYLT1,B4GALT7,GLCE,HS3ST5,HS6ST3 |
| 2.991e-02 | -3.51 | V$ZID_01 | MSigDB lists | V$ZID_01 | 240 | 33 | 17377 | 1707 |
UST,AMOTL1,STXBP6,PLAG1,SETBP1,LRRC49,TNKS1BP1,ARHGAP44,NELL2,SERINC2,ACVR2A,MARCKS,PPP2R2B,GFI1,FKBP14,SEMA6C,RIN2,MEIS2,MYO10,PLEKHA8,MSTN,ESRRG,THSD4,DCHS1,FGFR1,ZIC1,ZNF711,ENPP1,SERPINI1,CERS1,THAP10,HOXB9,CNTN1 |
| 2.993e-02 | -3.51 | heart formation | biological process | GO:0060914 | 13 | 4 | 17256 | 1658 |
SMARCD3,BMPR1A,BMP4,MEF2C |
| 2.993e-02 | -3.51 | regulation of plasma membrane organization | biological process | GO:1903729 | 13 | 4 | 17256 | 1658 |
GSN,SH3GL2,TMEFF2,PRKCD |
| 2.993e-02 | -3.51 | norepinephrine metabolic process | biological process | GO:0042415 | 13 | 4 | 17256 | 1658 |
GATA3,RNF180,PRKN,MOXD1 |
| 2.993e-02 | -3.51 | very long-chain fatty acid biosynthetic process | biological process | GO:0042761 | 13 | 4 | 17256 | 1658 |
ELOVL4,ELOVL7,ELOVL3,HACD1 |
| 2.993e-02 | -3.51 | negative regulation of muscle adaptation | biological process | GO:0014745 | 13 | 4 | 17256 | 1658 |
SMAD3,ERRFI1,ATP2B4,NOS3 |
| 2.993e-02 | -3.51 | plasma membrane tubulation | biological process | GO:0097320 | 13 | 4 | 17256 | 1658 |
PACSIN1,SNX9,FNBP1L,PACSIN3 |
| 2.993e-02 | -3.51 | cellular response to epinephrine stimulus | biological process | GO:0071872 | 13 | 4 | 17256 | 1658 |
RYR2,PDE4D,ATP2B4,SNCA |
| 2.993e-02 | -3.51 | glucose import | biological process | GO:0046323 | 13 | 4 | 17256 | 1658 |
SLC2A12,SLC2A13,SESN2,SLC2A6 |
| 2.993e-02 | -3.51 | lysine metabolic process | biological process | GO:0006553 | 13 | 4 | 17256 | 1658 |
PHYKPL,HYKK,AADAT,AASS |
| 2.993e-02 | -3.51 | regulation of nephron tubule epithelial cell differentiation | biological process | GO:0072182 | 13 | 4 | 17256 | 1658 |
YAP1,GATA3,FAT4,WWTR1 |
| 2.993e-02 | -3.51 | regulation of transcription from RNA polymerase II promoter involved in heart development | biological process | GO:1901213 | 13 | 4 | 17256 | 1658 |
MSX1,BMPR1A,ACVR1,BMP4 |
| 2.993e-02 | -3.51 | cellular response to cholesterol | biological process | GO:0071397 | 13 | 4 | 17256 | 1658 |
LRP6,HMGCS1,MLC1,GPLD1 |
| 2.995e-02 | -3.51 | GS | prosite domains | PS51256 | 7 | 3 | 12060 | 1278 |
BMPR1A,ACVR1,ACVR1C |
| 2.995e-02 | -3.51 | SPR | prosite domains | PS51227 | 7 | 3 | 12060 | 1278 |
SPRY4,SPRED3,SPRY2 |
| 2.996e-02 | -3.51 | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | 75 | 13 | 17377 | 1707 |
SLC7A1,PDK1,LGALS3,TM9SF2,ITGA6,SERPINI1,LMAN2,GAS6,TNFRSF17,CANX,AARS,CKAP4,PYCR1 |
| 2.996e-02 | -3.51 | GO_ARTERY_DEVELOPMENT | MSigDB lists | GO_ARTERY_DEVELOPMENT | 75 | 13 | 17377 | 1707 |
BMPR2,HPGD,PRICKLE1,WNT11,ADAMTS6,PRDM1,ACVR2B,BMP4,NRP1,SMAD6,HOXA1,PDGFRB,HEY1 |
| 2.996e-02 | -3.51 | GO_NEURAL_CREST_CELL_DIFFERENTIATION | MSigDB lists | GO_NEURAL_CREST_CELL_DIFFERENTIATION | 75 | 13 | 17377 | 1707 |
SEMA6B,ACVR1,SEMA4F,LRP6,SEMA3C,OVOL2,BMPR1A,NRP1,SEMA3A,SEMA6A,SEMA6C,SNAI2,MEF2C |
| 2.996e-02 | -3.51 | GO_REGULATION_OF_BMP_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_BMP_SIGNALING_PATHWAY | 75 | 13 | 17377 | 1707 |
NBL1,MSX1,BMPR2,FBN1,CHRDL1,ACVR2A,BMP4,SMAD6,NEO1,SKI,FZD1,PCSK6,DKK1 |
| 2.997e-02 | -3.51 | cholesterol biosynthesis I | BIOCYC pathways | META_PWY66-341 | 11 | 4 | 902 | 105 |
SQLE,CYP51A1,DHCR7,MSMO1 |
| 2.997e-02 | -3.51 | NAD de novo biosynthesis | BIOCYC pathways | HUMAN_NADSYN-PWY | 11 | 4 | 902 | 105 |
NMNAT3,TDO2,KMO,QPRT |
| 2.997e-02 | -3.51 | cholesterol biosynthesis II (via 24,25-dihydrolanosterol) | BIOCYC pathways | META_PWY66-3 | 11 | 4 | 902 | 105 |
SQLE,CYP51A1,DHCR7,MSMO1 |
| 2.997e-02 | -3.51 | cholesterol biosynthesis III (via desmosterol) | BIOCYC pathways | META_PWY66-4 | 11 | 4 | 902 | 105 |
SQLE,CYP51A1,DHCR7,MSMO1 |
| 3.000e-02 | -3.51 | neuron projection terminus | cellular component | GO:0044306 | 127 | 19 | 18223 | 1724 |
KCNIP3,GRIK2,PRSS12,BLVRB,LRRK2,OPHN1,ROR1,KCNC4,PFN2,BAIAP2,SNCA,UNC13B,FLRT3,ITGA2,RGS10,PTPRN2,PACSIN1,MME,CHRM3 |
| 3.001e-02 | -3.51 | GSE6259_DEC205_POS_DC_VS_BCELL_UP | MSigDB lists | GSE6259_DEC205_POS_DC_VS_BCELL_UP | 147 | 22 | 17377 | 1707 |
DLGAP1,FGFR4,GSTM2,TSPAN15,THSD4,CD276,FZD8,BIK,GPSM1,TMEM200C,HECW2,AMIGO1,COLEC10,GUCY1A2,TMEM74,CCDC120,CACNB2,REEP1,SMAD6,DCBLD1,DIRC2,HS6ST3 |
| 3.007e-02 | -3.50 | GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP | 172 | 25 | 17377 | 1707 |
BCL11B,CELSR1,TBC1D8B,CHCHD7,ST6GAL1,KIF5C,GDPD5,SESN1,SLC46A3,TPK1,FKBP11,AK1,GSN,POU5F1B,ABCA5,AKT3,GBP1,EIF1,TSC22D1,TPM1,MYO6,NEUROG2,NR3C2,ZFP36L2,RASGRP1 |
| 3.007e-02 | -3.50 | GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN | 172 | 25 | 17377 | 1707 |
EML5,BCL7A,PRSS16,RNF144A,KLHL23,EPS8,NFE2L1,TCEAL3,LACC1,BATF,ZNF219,NPDC1,KBTBD11,C4BPB,HERPUD1,BATF3,CXCL10,GALNT1,TMEM237,ZNF438,KIAA1671,EOMES,PIK3AP1,RAB31,FNBP1L |
| 3.007e-02 | -3.50 | V$AP2REP_01 | MSigDB lists | V$AP2REP_01 | 172 | 25 | 17377 | 1707 |
NUDT10,ACVR1,SHANK2,JPH1,PANK1,ZDHHC15,VIM,BTBD9,TNKS1BP1,HMCN1,NT5DC2,EYA4,ARHGAP44,DYRK1B,PCBP4,PDE10A,ZIC5,TSC22D1,BMP1,FHIT,DNHD1,MAST4,NR3C2,COBL,PCSK6 |
| 3.008e-02 | -3.50 | mTOR signaling pathway | Pathway Interaction DB | mtor_4pathway | 60 | 13 | 2226 | 278 |
PXN,EEF2,EIF4EBP1,SREBF1,DEPTOR,SGK1,BNIP3,PLD1,PRKCA,PPARGC1A,BTRC,SFN,DDIT4 |
| 3.012e-02 | -3.50 | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 970 | 113 | 17377 | 1707 |
CREB3L2,ACVR1,OTX1,GATA3,LILRB1,CTBP2,CEBPA,CHUK,STAT5B,LPIN3,IKZF2,TRPS1,SKI,EPCAM,TLR3,EOMES,GRHL1,ACVR2A,DAB2IP,POU2F2,MET,TLR4,ETV1,POU3F3,GLI1,NKX2-1,MEIS2,ATF4,SMAD9,NR6A1,NFIA,NFE2L1,MEF2B,YAP1,SATB2,ATF3,PYGO1,ATOH1,BATF,CD40,BCL11A,AHRR,SMAD3,CXCL10,IKZF3,KLF12,INSIG1,WWTR1,NCOA7,TNFRSF1A,KLF5,HGF,DLX2,DBP,BMPR1A,PPARGC1A,HOXB9,MEF2C,HEY1,BCL11B,RUNX2,BMPR2,CKAP2,REL,ITGA6,FZD8,PLAG1,APBB1,OVOL2,P2RY1,BMP6,NKX6-1,ZBTB38,GATA2,BHLHA15,MYC,SREBF1,EBF4,GTF2F2,TFAP2A,LRP6,MYO6,GLIS1,BARX1,MED12L,CEBPD,RAX,MICAL2,SLC40A1,MSX1,RHOQ,NR4A1,ESRRG,MAFB,ZFPM2,SKAP1,ZIC1,RERE,CEBPB,EBF1,PLAGL1,TERT,HEYL,XBP1,HOXD13,PAX9,BMP4,NKX2-8,SHOX2,SMYD3,FOXA1,DDIT3,SIX2 |
| 3.012e-02 | -3.50 | Galactose-bd-like_sf | interpro domains | IPR008979 | 83 | 14 | 18492 | 1811 |
EPHA3,MYCBP2,CNTNAP3,CPXM2,BTBD9,EPHB6,FBXO27,EPHB1,NRP1,DDR1,DCBLD1,PCSK5,DCBLD2,PCSK6 |
| 3.012e-02 | -3.50 | Cys-rich_flank_reg_C | interpro domains | IPR000483 | 83 | 14 | 18492 | 1811 |
LGI2,LRRC55,TLR3,SLITRK2,LRRN1,FLRT3,SLITRK5,CHADL,NTRK3,AMIGO1,ADGRA3,TLR6,TLR4,SLIT2 |
| 3.015e-02 | -3.50 | regulation of catecholamine metabolic process | biological process | GO:0042069 | 19 | 5 | 17256 | 1658 |
GPR37,PRKN,ABAT,PDE1B,SNCA |
| 3.015e-02 | -3.50 | gas transport | biological process | GO:0015669 | 19 | 5 | 17256 | 1658 |
HBG2,HBE1,IPCEF1,CA2,MYC |
| 3.015e-02 | -3.50 | negative regulation of chondrocyte differentiation | biological process | GO:0032331 | 19 | 5 | 17256 | 1658 |
EFEMP1,CHADL,BMP4,NKX3-2,SNAI2 |
| 3.015e-02 | -3.50 | ventricular cardiac muscle cell action potential | biological process | GO:0086005 | 19 | 5 | 17256 | 1658 |
RYR2,PKP2,SCN5A,KCND3,ANK2 |
| 3.015e-02 | -3.50 | negative regulation of translational initiation | biological process | GO:0045947 | 19 | 5 | 17256 | 1658 |
ATF4,PAIP2B,EIF4EBP1,RPL13A,C8orf88 |
| 3.015e-02 | -3.50 | regulation of dopamine metabolic process | biological process | GO:0042053 | 19 | 5 | 17256 | 1658 |
GPR37,PRKN,ABAT,PDE1B,SNCA |
| 3.027e-02 | -3.50 | regulation of neuron death | biological process | GO:1901214 | 281 | 37 | 17256 | 1658 |
EFNB2,TYRO3,PRKN,TRIM2,GRIK2,GABRB2,REL,DHCR24,GATA3,EPHB1,AARS,DDIT4,KMO,TFAP2A,TLR4,STXBP1,RRAS2,FZD1,BDNF,ATF4,DCC,LRRK2,AGAP2,RACK1,TLR6,DKK1,SNCA,CEBPB,TERT,WFS1,NCOA7,NRP1,PPARGC1A,UNC5B,DDIT3,MEF2C,RETREG1 |
| 3.027e-02 | -3.50 | negative regulation of nervous system development | biological process | GO:0051961 | 281 | 37 | 17256 | 1658 |
EFNB2,DNM3,ID1,FGF13,ROBO2,LDLR,LRP4,NTRK3,FOXG1,SKI,NKX6-1,CNTN4,SEMA4F,KIAA0319,ADCY6,FIG4,ZNF365,GFI1,SLIT2,PRKACB,GPR161,DCC,RAPGEF2,LRRK2,VIM,ID3,NRG3,TERT,PLK2,PTPRS,SEMA3C,INPP5F,BMPR1A,DLX2,NRP1,SPART,SEMA3A |
| 3.030e-02 | -3.50 | HSPB2 (heat shock protein family B (small) member 2) | protein interactions | 3316 | 96 | 16 | 17029 | 1718 |
BEX4,GARS,GAPDH,ALDH2,RPS11,ALDOA,FHL2,PKP2,RYR2,MYOM2,ENO1,NT5DC2,SNCA,DUSP1,CYP1B1,DDIT4 |
| 3.030e-02 | -3.50 | VASP (vasodilator stimulated phosphoprotein) | protein interactions | 7408 | 96 | 16 | 17029 | 1718 |
EVL,FN1,NR4A1,TES,LRP4,APBB1,NPM1,ENAH,PFN2,TRIM9,GSN,FAT1,ABI3,PRKG1,RAB30,LPP |
| 3.031e-02 | -3.50 | RAMASWAMY_METASTASIS_DN | MSigDB lists | RAMASWAMY_METASTASIS_DN | 60 | 11 | 17377 | 1707 |
ABLIM1,KCNAB1,CHRNA5,NR4A1,REL,CACNA1E,PRKG2,LIMCH1,ROR1,RAB30,MAP1B |
| 3.035e-02 | -3.49 | vitamin B6 binding | molecular function | GO:0070279 | 53 | 10 | 17224 | 1680 |
GPT2,MOCOS,AADAT,GCAT,CBS,PHYKPL,ABAT,ETNPPL,GLDC,CTH |
| 3.035e-02 | -3.49 | pyridoxal phosphate binding | molecular function | GO:0030170 | 53 | 10 | 17224 | 1680 |
GPT2,MOCOS,AADAT,GCAT,CBS,PHYKPL,ABAT,ETNPPL,GLDC,CTH |
| 3.036e-02 | -3.49 | GSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP | MSigDB lists | GSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP | 189 | 27 | 17377 | 1707 |
PDLIM7,WASF3,ANTXR2,SV2B,PXN,BMPR2,TMEM43,CACNA1E,KLHL4,SYT12,GSTM4,TMEM126A,SLC36A4,NTRK3,GABRR2,AMDHD1,EYA4,ZNF711,ZNF362,SEC16B,KCNG1,KLHL29,HSPA2,KCTD1,BTRC,C3orf67,LPP |
| 3.036e-02 | -3.49 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_DN | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_DN | 189 | 27 | 17377 | 1707 |
MAN2B2,SSH3,SEMA6B,TMEM63C,USP2,SLC36A1,MVD,CAPN5,EPS8,CUEDC2,ATP11A,RASSF8,RSL24D1,SEC16B,GPR160,EMILIN2,NDUFB8,PAM,SH3PXD2B,SLC1A5,RNF157,ENO1,LIFR,GATM,RAPGEF5,LRP12,CKAP4 |
| 3.036e-02 | -3.49 | GSE17721_LPS_VS_POLYIC_8H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_8H_BMDC_DN | 189 | 27 | 17377 | 1707 |
GCA,MID2,MOCOS,PRSS16,PDK1,PNRC1,FGF13,STAT4,VAMP8,ARID5B,DUSP9,SCD,WNT11,VIM,ABHD6,AARS,NEDD4,STK24,MCOLN2,AHRR,NAP1L5,FGR,REEP1,BCL6,ZBTB20,TLR4,B4GALT6 |
| 3.036e-02 | -3.49 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_DN | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_DN | 189 | 27 | 17377 | 1707 |
TNK2,ALDH2,ITGA6,LRMP,DEPTOR,RABAC1,FAM198B,GAS6,ATP1B1,DOCK5,DOCK2,GSN,GALNT1,AK1,ABI3BP,PRKCB,TSC22D1,ZNF521,PTPRS,TSPAN13,MED7,NRP1,TNFRSF17,SLC45A3,CSRP2,CTNND2,IGFBP3 |
| 3.036e-02 | -3.49 | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_UP | 189 | 27 | 17377 | 1707 |
VEGFC,LATS2,RHOQ,ALDH2,SLC6A9,SKAP2,SLC27A2,CYP4V2,LITAF,MORC4,C1R,SORBS3,IL18R1,SCIN,GABARAPL1,TIFA,RPS6KA2,BMP1,RCN3,HOXD13,PROS1,CERS4,CTTN,GEM,GATM,CSRP2,B4GALT6 |
| 3.036e-02 | -3.49 | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_UP | MSigDB lists | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_UP | 189 | 27 | 17377 | 1707 |
TYRO3,PDLIM7,SH3BP2,ALDH2,PNRC1,REL,ELOVL3,RASD1,VIM,HBE1,ZFPM2,CA8,SESN1,F3,COL22A1,ENTPD7,PRKCD,TSC22D1,GRIN2D,ZNF808,TMEM37,PTPRE,TNFRSF11A,ZFP36L2,RASGRP1,CKAP4,PHC1 |
| 3.037e-02 | -3.49 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | 275 | 37 | 17377 | 1707 |
TYRO3,RGS16,ENO2,TRIM16,ZCCHC24,ITGA6,LRP4,LDLR,DHCR24,ADD2,PCDH7,TUBB4A,MYC,PRKCD,FIG4,NPTXR,IGSF3,GLDC,DBN1,FADS1,PRAME,MYO10,SLC27A2,SLITRK5,PDE8A,STEAP1,BCL11A,INSIG1,PTK7,WFS1,ATP7B,SLC7A5,SQLE,MYOM2,ERCC5,SLC1A5,DHCR7 |
| 3.041e-02 | -3.49 | human chr8p22 | chromosome location | human chr8p22 | 24 | 5 | 26185 | 1967 |
PSD3,SLC7A2,C8orf48,MSR1,MTUS1 |
| 3.041e-02 | -3.49 | human chr2q32.2 | chromosome location | human chr2q32.2 | 24 | 5 | 26185 | 1967 |
SLC40A1,C2orf88,MFSD6,MSTN,INPP1 |
| 3.043e-02 | -3.49 | TNFR/NGFR_Cys_rich_reg | interpro domains | IPR001368 | 25 | 6 | 18492 | 1811 |
TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A |
| 3.043e-02 | -3.49 | cellular response to glucose stimulus | biological process | GO:0071333 | 69 | 12 | 17256 | 1658 |
PRKAA2,IRS2,RAB11FIP5,IGF1R,UNC13B,XBP1,ERN1,PTPRN2,GAS6,RACK1,PCK2,PPARGC1A |
| 3.044e-02 | -3.49 | embryo development ending in birth or egg hatching | biological process | GO:0009792 | 565 | 68 | 17256 | 1658 |
ACVR1,ST14,PLXNA2,GATA3,CEBPA,KIAA1217,SKI,EOMES,DACT1,TBC1D32,ACVR2A,PRKACB,FZD1,INTU,NKX3-2,SATB2,WNT11,RARRES2,FGFR1,SMAD3,PTK7,SEMA3C,BMPR1A,DLX2,TPM1,TANC2,VASH2,APBA2,HOXB9,COBL,PCSK5,HEY1,MEF2C,RUNX2,STOX2,BMPR2,CELSR1,SEC24D,OVOL2,APBA1,PHGDH,HOPX,IRX5,MGAT1,GATA2,TFAP2A,LRP6,YBX3,NOS3,B9D1,EPB41L5,MSX1,DCHS1,PRICKLE1,PRDM1,ZFPM2,HOXA1,DKK1,HEG1,CEBPB,CECR2,WDR19,PCGF2,BMP4,SHOX2,MMP16,SIX2,FOXA1 |
| 3.045e-02 | -3.49 | Pathways in cancer | KEGG pathways | hsa05200 | 395 | 52 | 7161 | 730 |
GNG12,LPAR2,FN1,FGF13,ARHGEF11,FZD8,ITGA6,LAMC3,COL4A5,CHUK,STAT5B,CTBP2,CEBPA,PRKCA,RAC3,CTNNA2,MECOM,IGF1R,MYC,ADCY6,MET,PDGFRB,PRKACB,RASGRP1,GLI1,FZD1,PTCH2,VEGFC,COL4A3,DCC,FZD4,TGFA,COL4A4,FGF12,ADCY1,WNT11,FGF17,PLCB1,FGFR1,GNAI1,SMAD3,TCF7L1,PRKCB,GNB4,AKT3,ITGA2,CCNA1,LAMB1,HGF,PLD1,BMP4,MAPK10 |
| 3.051e-02 | -3.49 | GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | MSigDB lists | GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | 139 | 21 | 17377 | 1707 |
PFKFB4,PDK1,RNF145,PTPN6,DNAJC6,MCTP2,ATP1B1,MFSD6,EXOG,KREMEN1,GSN,TECPR1,SLC30A4,PRKCB,TECPR2,ADCY6,ST8SIA1,FAM84B,SLFN5,AMPD1,SLC16A10 |
| 3.055e-02 | -3.49 | human chr8q23.2 | chromosome location | human chr8q23.2 | 4 | 2 | 26185 | 1967 |
KCNV1,SYBU |
| 3.063e-02 | -3.49 | gastrulation | biological process | GO:0007369 | 159 | 23 | 17256 | 1658 |
EPB41L5,ACVR1,FN1,BMPR2,WLS,UGDH,WNT11,ACVR2B,RACK1,DKK1,SMAD3,MMP15,EOMES,APELA,ITGA2,LAMB1,ITGB3,ACVR2A,LRP6,BMPR1A,BMP4,SIX2,DUSP1 |
| 3.068e-02 | -3.48 | Metabolite levels(PMID:19043545) | GWAS genes | Metabolite levels(PMID:19043545) | 8 | 4 | 2388 | 399 |
FADS1,PRKN,SV2B,FGF12 |
| 3.068e-02 | -3.48 | Amyotrophic lateral sclerosis(PMID:19451621) | GWAS genes | Amyotrophic lateral sclerosis(PMID:19451621) | 8 | 4 | 2388 | 399 |
SELL,DISC1,MORN2,CNTN4 |
| 3.079e-02 | -3.48 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | 83 | 14 | 17377 | 1707 |
PTPRC,ENTPD1,TYMP,GAPDH,PRKCB,ALDOC,RGS10,RAB31,MOXD1,DOCK2,SFN,WARS,ISG20,CD53 |
| 3.079e-02 | -3.48 | HOEBEKE_LYMPHOID_STEM_CELL_DN | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_DN | 83 | 14 | 17377 | 1707 |
CEBPB,CFH,PMAIP1,SLC39A8,FHL2,LAPTM4B,LIMCH1,TNS1,MARCKS,ATP1B1,RAB38,MLLT3,MECOM,PLS3 |
| 3.079e-02 | -3.48 | GO_PLASMA_MEMBRANE_RAFT | MSigDB lists | GO_PLASMA_MEMBRANE_RAFT | 83 | 14 | 17377 | 1707 |
MYO1D,SCN5A,BMPR2,LRP4,LRRK2,LRP6,ATP1B1,BMPR1A,LCP2,MLC1,CDH2,NOS1AP,ATP2B4,NOS3 |
| 3.082e-02 | -3.48 | regulation of neurological system process | biological process | GO:0031644 | 109 | 17 | 17256 | 1658 |
WASF3,SHANK2,LRRK2,FGF12,NLGN4X,ABAT,NRXN1,CBLN1,BAIAP2,TYMP,UNC13B,ITGA2,GRIN2D,HGF,FIG4,MYRF,RIMS2 |
| 3.082e-02 | -3.48 | GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL_BY_SARCOPLASMIC_RETICULUM | MSigDB lists | GO_REGULATION_OF_RELEASE_OF_SEQUESTERED_CALCIUM_ION_INTO_CYTOSOL_BY_SARCOPLASMIC_RETICULUM | 25 | 6 | 17377 | 1707 |
RYR2,GSTO1,GSTM2,PDE4D,ASPH,ANK2 |
| 3.082e-02 | -3.48 | LOPES_METHYLATED_IN_COLON_CANCER_UP | MSigDB lists | LOPES_METHYLATED_IN_COLON_CANCER_UP | 25 | 6 | 17377 | 1707 |
TNFRSF10C,TMEFF2,APBA1,APBA2,MGMT,NKX2-1 |
| 3.082e-02 | -3.48 | GO_REPLACEMENT_OSSIFICATION | MSigDB lists | GO_REPLACEMENT_OSSIFICATION | 25 | 6 | 17377 | 1707 |
INPPL1,RUNX2,BMP4,BMP6,MMP16,MEF2C |
| 3.082e-02 | -3.48 | GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 25 | 6 | 17377 | 1707 |
PRICKLE1,CXCL10,MSX1,BHLHA15,XBP1,DKK1 |
| 3.082e-02 | -3.48 | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | MSigDB lists | REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | 25 | 6 | 17377 | 1707 |
ADCY6,GNG12,CACNB2,GNB4,GNAO1,GNAI1 |
| 3.082e-02 | -3.48 | MODULE_343 | MSigDB lists | MODULE_343 | 25 | 6 | 17377 | 1707 |
CBS,CA2,EHHADH,UROS,CA8,ACO1 |
| 3.082e-02 | -3.48 | GO_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS | MSigDB lists | GO_EPITHELIAL_TUBE_BRANCHING_INVOLVED_IN_LUNG_MORPHOGENESIS | 25 | 6 | 17377 | 1707 |
YAP1,BMP4,CELSR1,SPRY2,FOXA1,NKX2-1 |
| 3.082e-02 | -3.48 | GO_ENDOCHONDRAL_OSSIFICATION | MSigDB lists | GO_ENDOCHONDRAL_OSSIFICATION | 25 | 6 | 17377 | 1707 |
INPPL1,RUNX2,BMP4,MMP16,BMP6,MEF2C |
| 3.082e-02 | -3.48 | GO_MEMBRANE_ASSEMBLY | MSigDB lists | GO_MEMBRANE_ASSEMBLY | 25 | 6 | 17377 | 1707 |
NLGN4X,NRXN1,MAGI2,CDH2,PTPRD,LRP4 |
| 3.084e-02 | -3.48 | BAND41 | prints domains | PR00935 | 25 | 6 | 4652 | 458 |
EPB41L5,EPB41L3,FARP1,PTPN13,FRMD5,PTPN21 |
| 3.089e-02 | -3.48 | Collagen degradation | REACTOME pathways | R-HSA-1442490 | 40 | 8 | 10287 | 971 |
MMP15,COL9A3,COL25A1,COL18A1,COL19A1,PHYKPL,COL14A1,COL9A2 |
| 3.089e-02 | -3.48 | V$GATA1_03 | MSigDB lists | V$GATA1_03 | 232 | 32 | 17377 | 1707 |
ARHGAP26,RASAL2,ENO2,GABRG2,NDRG2,ADAMTS6,PRDM8,CREB5,MECOM,PCDH7,KCNN2,RALGPS2,FLRT3,LHX6,ACVR2A,ETV1,GLI1,MEIS2,FZD4,JPH1,CD40,ZFPM2,SNCA,ZIC1,ADAMTS3,FMO4,MID1,NR3C2,MMP16,FOXA1,BTRC,MEF2C |
| 3.094e-02 | -3.48 | KRAS.LUNG_UP.V1_UP | MSigDB lists | KRAS.LUNG_UP.V1_UP | 131 | 20 | 17377 | 1707 |
BTC,SH2D2A,CYP2J2,FBXO4,OGDHL,LILRB1,KIF5C,TTC22,DOCK2,DCBLD2,HTR7,NELL2,ADAMTS3,MAGEA3,ITGA2,SLCO5A1,PRKG2,EGFL7,NRP1,MAGEA6 |
| 3.097e-02 | -3.47 | - | gene3d domains | 2.60.120.260 | 77 | 14 | 8148 | 867 |
EPHA3,MYCBP2,CNTNAP3,CPXM2,BTBD9,EPHB6,FBXO27,EPHB1,NRP1,DDR1,DCBLD1,PCSK5,DCBLD2,PCSK6 |
| 3.098e-02 | -3.47 | L27 | prosite domains | PS51022 | 12 | 4 | 12060 | 1278 |
LIN7A,MPDZ,MPP7,MPP2 |
| 3.098e-02 | -3.47 | COS | prosite domains | PS51262 | 12 | 4 | 12060 | 1278 |
FSD1,TRIM9,MID2,MID1 |
| 3.098e-02 | -3.47 | GO_DEPHOSPHORYLATION | MSigDB lists | GO_DEPHOSPHORYLATION | 258 | 35 | 17377 | 1707 |
INPPL1,DUSP8,PTPRD,UBASH3B,PTPN21,LPIN3,INPP1,EYA4,PPP2R3A,PPM1E,CDC14B,FIG4,PTPRE,DUSP1,PFKFB4,SSH3,PPP1R3D,PFKFB2,PTPRU,PTPN6,PTPN13,DNAJC6,DUSP9,CTTNBP2NL,LHPP,NT5DC2,PTPRC,PTPRJ,DUSP19,INPP4B,PTPRN2,PTPRS,INPP5F,BTRC,PSPH |
| 3.099e-02 | -3.47 | SMAD5 (SMAD family member 5) | protein interactions | 4090 | 66 | 12 | 17029 | 1718 |
SMAD3,HBG2,ACVR1,RUNX2,RYR2,HECW2,YAP1,HOXD13,SMAD6,BMP6,NEDD4,SKI |
| 3.099e-02 | -3.47 | SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1) | protein interactions | 6654 | 66 | 12 | 17029 | 1718 |
TNIK,SORBS1,PTPN6,ABI3,EPS8,TNFRSF1A,PACSIN3,LRRK1,PACSIN1,MET,SNX9,FGFR1 |
| 3.099e-02 | -3.47 | LOC101929876 (40S ribosomal protein S26) | protein interactions | 101929876 | 66 | 12 | 17029 | 1718 |
RPS20,RPL26,RPL12,RPS11,RPL21,RPS12,RPL4,RPL26L1,RPS23,RPL13A,RPS13,RPL34 |
| 3.099e-02 | -3.47 | ZF_DAG_PE_1 | prosite domains | PS00479 | 56 | 11 | 12060 | 1278 |
CHN1,VAV3,ARHGEF28,CHN2,UNC13B,PRKCB,PRKCD,PRKCQ,CDC42BPA,PRKCA,RASGRP1 |
| 3.106e-02 | -3.47 | regulation of hemostasis | biological process | GO:1900046 | 77 | 13 | 17256 | 1658 |
HPSE,UBASH3B,PRKCD,PRKG1,PRKCQ,ABAT,PROS1,F12,PRKCA,TLR4,SYK,F3,NOS3 |
| 3.106e-02 | -3.47 | regulation of blood coagulation | biological process | GO:0030193 | 77 | 13 | 17256 | 1658 |
HPSE,UBASH3B,PRKCD,PRKG1,PRKCQ,ABAT,PROS1,F12,PRKCA,TLR4,SYK,F3,NOS3 |
| 3.118e-02 | -3.47 | negative regulation of small GTPase mediated signal transduction | biological process | GO:0051058 | 54 | 10 | 17256 | 1658 |
RIPOR2,RASAL2,BCL6,RASA3,DAB2IP,SPRY4,MET,SPRY2,SLIT2,ARHGAP44 |
| 3.118e-02 | -3.47 | GSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_UP | MSigDB lists | GSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_UP | 181 | 26 | 17377 | 1707 |
TRDMT1,UNC5C,TNK2,FARP1,PXN,KCNQ3,RECK,RUSC2,CAPN5,RGS20,LMCD1,SDC3,KCND3,RTN1,MAPKAPK2,RND2,MSC,MAGEA12,KCTD15,GATA2,PPFIBP1,MCC,CLMN,ZNF365,BARX1,PGBD5 |
| 3.118e-02 | -3.47 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 181 | 26 | 17377 | 1707 |
CREB3L2,UST,MICAL2,ANTXR2,ALOX5AP,LGALS3,MLF1,PREX1,TTYH2,PHACTR2,COTL1,LACC1,NPDC1,GDPD5,CRYBG3,HOPX,TYMP,TLR3,ZBTB38,PAM,KIF21A,ST8SIA1,FAR2,KIF1B,ATP2B4,STOM |
| 3.118e-02 | -3.47 | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | 181 | 26 | 17377 | 1707 |
MAN2B2,PDK1,ZNF395,ST14,HEBP1,ARID5B,LILRB1,HERC5,PDE8A,SLC25A28,NPC2,BBS9,PLEKHB1,ABLIM1,MSC,RPL28,KIAA0355,TSC22D1,KIAA0513,TNFSF15,KLF9,RNF130,IPCEF1,PTPRCAP,CKAP4,PCSK5 |
| 3.118e-02 | -3.47 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 181 | 26 | 17377 | 1707 |
RPS20,GCA,VNN2,RPL26,DNM3,REL,PSTPIP2,OPHN1,CR2,KIF21B,STK24,RPL12,IKZF3,BACH2,FRY,PLAGL1,PRKCB,KIAA0355,CSF1,TSC22D1,ESD,SNX10,FNBP1L,AGL,PRKACB,PKIA |
| 3.118e-02 | -3.47 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_DN | 181 | 26 | 17377 | 1707 |
PFKFB4,PLA2G4A,PAK1,FN1,TUBA1A,UROS,JDP2,MPP1,GPR65,LPCAT2,BLVRB,VAMP8,CUEDC2,CHSY1,FAM13A,ABHD6,CHN2,NACC2,EEPD1,KIAA0513,RNF130,TLR4,TNFRSF11A,CEBPD,CRYL1,MEF2C |
| 3.118e-02 | -3.47 | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_DN | MSigDB lists | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_DN | 181 | 26 | 17377 | 1707 |
LGALS3,FGF13,AARS,PHLDA2,CA13,HOPX,F3,SPNS1,ATXN7L1,TRIB3,ALDOC,KCNG1,SLC7A5,PRELID1,MCC,PAM,POF1B,PTPRS,UACA,BEND4,MAPK13,SH3PXD2B,IQGAP3,FNBP1L,SPRY2,CKAP4 |
| 3.118e-02 | -3.47 | GSE4142_PLASMA_CELL_VS_MEMORY_BCELL_UP | MSigDB lists | GSE4142_PLASMA_CELL_VS_MEMORY_BCELL_UP | 181 | 26 | 17377 | 1707 |
STOX2,PLSCR4,COL6A2,GAPDH,ELOVL4,RASAL2,COL4A3,CELSR3,PTPRU,SCN8A,SLC25A27,FERMT2,IGF2BP2,MAPK4,SLC7A2,ILDR2,MAP1B,KCNAB1,CHRDL1,CLMN,IQSEC2,VASH2,SMAD6,ETV1,NUDT17,PCSK5 |
| 3.118e-02 | -3.47 | GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_DN | MSigDB lists | GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_DN | 181 | 26 | 17377 | 1707 |
GPR176,HBG2,TCP11L2,LGALS3,TSPAN15,ARID5B,FHL2,BTBD9,ISYNA1,ATP11A,NDFIP2,FBXO36,BMP6,HOXA1,NCS1,SMPDL3B,PCDH7,HOPX,TXNDC5,ADPRHL1,IKZF3,SLC7A11,SCN1B,ALDOC,PRKG2,KLF9 |
| 3.118e-02 | -3.47 | GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP | MSigDB lists | GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP | 181 | 26 | 17377 | 1707 |
MN1,VEGFC,MOB1B,PAK1,CARD6,IL15,RECK,GPR65,ATP8A1,PSD3,LRRC49,RNF24,SLC36A4,SAV1,TEX9,CD53,ANKRD42,FBXO32,TECPR1,HLF,CA2,SLC30A4,RAP2A,NAP1L3,ZFP36L2,SMPDL3A |
| 3.118e-02 | -3.47 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN | 181 | 26 | 17377 | 1707 |
PDK1,SIDT1,RNF145,PRSS12,RAPGEF4,IGF2BP2,NTRK3,ATP1B1,MFSD6,INPP1,SLCO3A1,KCNMB4,EOMES,SOAT2,LRRC6,NACC2,GPR155,EHD3,ADCY6,SGK1,ZBTB20,ST8SIA1,TSPAN9,KIF1B,RASGRP1,LPP |
| 3.118e-02 | -3.47 | GSE7460_TREG_VS_TCONV_ACT_DN | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_DN | 181 | 26 | 17377 | 1707 |
MSX1,MYO10,LRMP,MCTP2,AGAP2,MGAT5B,TEX9,SLC46A3,SLCO3A1,MCOLN2,RNF150,EEF2,SLC30A4,RASGRF2,ITGB3,C1orf21,TNFRSF1A,OPN3,ADCY6,HS3ST3B1,RNF157,SMAD6,DHCR7,SLC9B1,CTNND2,PGBD5 |
| 3.123e-02 | -3.47 | cellular modified amino acid metabolic process | biological process | GO:0006575 | 185 | 26 | 17256 | 1658 |
PLA2G4A,OPLAH,ATP5IF1,GDAP1,VNN2,SERINC5,GSTM2,ALDH1L2,GSTM4,FASN,ASS1,STAT5B,GSTO1,CHAC1,GSTO2,PLOD2,ERO1B,PEMT,ALDH1L1,GHR,OSBPL5,SERINC2,GSTM3,P4HA1,GATM,PTGES |
| 3.124e-02 | -3.47 | transition metal ion homeostasis | biological process | GO:0055076 | 134 | 20 | 17256 | 1658 |
SLC40A1,PRKN,SLC39A8,SFXN4,ATOX1,ACO1,SLC25A28,BTBD9,SFXN3,BMP6,STEAP1,NEO1,SFXN1,SLC39A14,SLC22A17,SLC30A4,ATP7B,MYC,BDH2,STEAP3 |
| 3.127e-02 | -3.46 | YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon) | protein interactions | 7531 | 433 | 56 | 17029 | 1718 |
CGN,PRKN,FN1,TBC1D1,FBXO4,VAMP8,PKP2,NPM1,LCP2,RASSF8,EPB41L3,BAG3,ABLIM1,ASNS,IGF1R,MYC,REEP1,ACTA2,GSTM3,ERRFI1,TESPA1,ZFP36L2,GAB2,DISC1,ARHGEF28,LCA5,GAPDH,TUBA1A,PFKFB2,NPM3,CAP2,LRMP,LRRK2,FGF12,SPATA13,YAP1,WWC1,FERMT2,CBY1,VIM,SAV1,BAIAP2,SNCA,IRS2,KCNK15,BEX3,WWTR1,QPCTL,SH3BP4,GRB10,RPL4,TBC1D4,KIF1B,LARP1,BTRC,MAST1 |
| 3.128e-02 | -3.46 | GSE11367_CTRL_VS_IL17_TREATED_SMOOTH_MUSCLE_CELL_UP | MSigDB lists | GSE11367_CTRL_VS_IL17_TREATED_SMOOTH_MUSCLE_CELL_UP | 123 | 19 | 17377 | 1707 |
FARP1,PLBD2,RNF144A,NR6A1,PTPRU,MCTP2,TRAM1L1,BEGAIN,OBSCN,SLC1A3,MFSD6,COL14A1,AMDHD1,PDZD7,WWTR1,CNNM2,MORN4,KCTD1,OCLN |
| 3.129e-02 | -3.46 | CALRETICULIN_REPEAT | prosite domains | PS00805 | 3 | 2 | 12060 | 1278 |
CANX,CLGN |
| 3.129e-02 | -3.46 | DM10 | prosite domains | PS51336 | 3 | 2 | 12060 | 1278 |
EFHC1,EFHC2 |
| 3.129e-02 | -3.46 | HMA_1 | prosite domains | PS01047 | 3 | 2 | 12060 | 1278 |
ATP7B,ATOX1 |
| 3.129e-02 | -3.46 | ENOLASE | prosite domains | PS00164 | 3 | 2 | 12060 | 1278 |
ENO2,ENO1 |
| 3.129e-02 | -3.46 | GART | prosite domains | PS00373 | 3 | 2 | 12060 | 1278 |
ALDH1L2,ALDH1L1 |
| 3.129e-02 | -3.46 | SOHO | prosite domains | PS50831 | 3 | 2 | 12060 | 1278 |
SORBS3,SORBS1 |
| 3.129e-02 | -3.46 | ALDOLASE_CLASS_I | prosite domains | PS00158 | 3 | 2 | 12060 | 1278 |
ALDOC,ALDOA |
| 3.129e-02 | -3.46 | ABM | prosite domains | PS51725 | 3 | 2 | 12060 | 1278 |
NECAB2,NECAB1 |
| 3.129e-02 | -3.46 | RIBOSOMAL_L24 | prosite domains | PS01108 | 3 | 2 | 12060 | 1278 |
RPL26,RPL26L1 |
| 3.129e-02 | -3.46 | LEE_RECENT_THYMIC_EMIGRANT | MSigDB lists | LEE_RECENT_THYMIC_EMIGRANT | 198 | 28 | 17377 | 1707 |
PAK1,MICAL2,VAV3,SKAP2,TMEM65,UBASH3B,GATA3,ATP11A,TAF4B,GNAI1,HEG1,BCL11A,ZNF711,ZNF827,CACHD1,PMEPA1,MPP7,GNB4,DSG2,HPGD,TSPAN13,TOX,MARCKS,PDE4D,CMPK2,SPRY2,HACE1,LPP |
| 3.131e-02 | -3.46 | NIELSEN_GIST | MSigDB lists | NIELSEN_GIST | 91 | 15 | 17377 | 1707 |
ENTPD1,DPP10,RNF141,TTC1,CHN2,CA2,ABCC4,KLHL23,PRKAR2B,PRKCQ,SPRY4,MYO6,CLN5,ETV1,DYNC1I1 |
| 3.131e-02 | -3.46 | plasma membrane bounded cell projection assembly | biological process | GO:0120031 | 436 | 54 | 17256 | 1658 |
WASF3,TNIK,DNM3,INPPL1,TCTN2,CELSR3,RHOD,ITGA6,OPHN1,PIBF1,BBS9,TTC30B,TUBB4A,ABLIM1,LRRC6,CDC14B,DNAH6,RAP2A,EHD3,TBC1D32,CTTN,DYNC2H1,SEPT3,DNAH5,SNX10,B9D1,INTU,VAV3,DISC1,TMEM67,TUBA1A,ABCC4,SPATA6,RAPGEF2,SPATA13,TTC30A,CBY1,PRKAR2B,ARHGEF26,ARMC4,GSN,IFT81,TMEM237,WDR19,WWTR1,DYNC2LI1,KLF5,JHY,SEPT5,DNHD1,NRP1,FNBP1L,NPHP1,SHTN1 |
| 3.135e-02 | -3.46 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032436 | 85 | 14 | 17256 | 1658 |
LONRF1,TRIB3,RNF180,PRKN,RNF217,NOP53,RNF144A,PLK2,LRRK2,PRICKLE1,RNF125,CEBPA,RACK1,HERPUD1 |
| 3.135e-02 | -3.46 | regulation of JUN kinase activity | biological process | GO:0043506 | 85 | 14 | 17256 | 1658 |
PAK1,TNIK,FZD4,FZD8,ERN1,MAP3K21,DUSP19,DAB2IP,PKN1,TLR6,TNFRSF11A,SYK,MAP3K20,DKK1 |
| 3.135e-02 | -3.46 | iron ion homeostasis | biological process | GO:0055072 | 85 | 14 | 17256 | 1658 |
SFXN1,SLC40A1,SLC22A17,MYC,SFXN4,BDH2,ACO1,SLC25A28,STEAP3,BTBD9,SFXN3,BMP6,STEAP1,NEO1 |
| 3.137e-02 | -3.46 | regulation of response to oxidative stress | biological process | GO:1902882 | 93 | 15 | 17256 | 1658 |
GPR37,PRKN,SESN2,ATF4,LRRK2,NCOA7,PDE8A,HGF,RACK1,MET,SESN1,TLR4,TLR6,FZD1,PYCR1 |
| 3.140e-02 | -3.46 | modified amino acid binding | molecular function | GO:0072341 | 76 | 13 | 17224 | 1680 |
FTCDNL1,GSTM2,MARK1,FCHO2,GSTM4,OSBPL5,FASN,GSTM3,CBS,GAS6,PTGES,RASGRP1,SCIN |
| 3.144e-02 | -3.46 | phosphatidate phosphatase activity | molecular function | GO:0008195 | 13 | 4 | 17224 | 1680 |
PLPP1,LPIN3,PLPPR2,PLPP2 |
| 3.144e-02 | -3.46 | guanylate kinase activity | molecular function | GO:0004385 | 13 | 4 | 17224 | 1680 |
DLG2,MPP1,MAGI3,MPP2 |
| 3.144e-02 | -3.46 | nitric-oxide synthase binding | molecular function | GO:0050998 | 13 | 4 | 17224 | 1680 |
SCN5A,DNM3,ATP2B4,NOS1AP |
| 3.144e-02 | -3.46 | co-receptor binding | molecular function | GO:0039706 | 13 | 4 | 17224 | 1680 |
BMP4,LRRK2,NEO1,DKK1 |
| 3.146e-02 | -3.46 | bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-fibula-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 384 | 49 | 17385 | 1698 |
MAN2B2,LATS2,FN1,CFH,ARHGEF11,ACTL8,UBAC2,LILRB1,TJP1,NRXN1,RADIL,AARS,RNF180,TMEM53,SIPA1L2,SPEG,CA2,SEMA4F,SLC10A7,MPDZ,TMED9,TLN2,TBC1D9,SCN3A,TRPM4,TMC7,DBN1,BDNF,TNK2,SKAP2,KCNQ3,ABCC4,FZD4,KCNH5,PRDM13,OBSCN,PDE8A,SDK1,ZFPM2,TAF4B,SERGEF,SMPDL3B,ATPAF2,GPRC5B,ENPP6,PKN3,FAT1,SLC22A15,MAST1 |
| 3.146e-02 | -3.46 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_DN | 156 | 23 | 17377 | 1707 |
FAM171B,WASF3,ITPRIP,TDRD3,SCN8A,UBASH3B,C3orf52,JPH1,COLEC10,DOCK3,ARHGAP44,SYDE2,F3,DDIT4,TRPS1,ID3,KIAA0895,ANKRD31,CCBE1,GEM,TNFSF4,FAR2,ALG10B |
| 3.146e-02 | -3.46 | GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP | MSigDB lists | GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP | 156 | 23 | 17377 | 1707 |
ADAL,LRRC8B,ARID5B,MCOLN3,GATA3,GABRG2,VIM,SLC19A2,TGFBR3,SEMA4F,FRY,INSIG1,PDZD8,NCKAP1L,PMAIP1,GNB4,MATN2,B3GALT2,DYNC2H1,PDE4D,FAM84B,ALPK1,ZFP36L2 |
| 3.146e-02 | -3.46 | GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP | 156 | 23 | 17377 | 1707 |
LCA5,GRIK2,MYO10,WLS,ITGA6,DNAJC6,GTF2IRD1,TUBE1,MAFB,NTRK3,MBNL2,PFN2,MAGI3,DYRK1B,ID3,BACH2,PLXDC2,B3GALT2,DAB2IP,GFI1,RNF157,ALG10B,RRAGD |
| 3.150e-02 | -3.46 | V$PXR_Q2 | MSigDB lists | V$PXR_Q2 | 241 | 33 | 17377 | 1707 |
MPZL3,PRSS12,HEBP1,XYLT1,PLXNA2,NDRG2,HBE1,CREB5,IKZF2,SP8,CHST10,MAP1A,FABP6,SCRN1,ATRNL1,SMAD6,BDNF,MEIS2,RNF145,ABCC4,CYTH3,TNS1,ATP1B1,PLEKHA1,MBNL2,PTPRC,SMAD3,FGR,ALDOA,MPP2,TNFSF15,NRP1,NR3C2 |
| 3.151e-02 | -3.46 | human chr4q25 | chromosome location | human chr4q25 | 41 | 7 | 26185 | 1967 |
TIFA,CYP2U1,ALPK1,NEUROG2,ETNPPL,COL25A1,RPL34 |
| 3.152e-02 | -3.46 | CCTNTMAGA_UNKNOWN | MSigDB lists | CCTNTMAGA_UNKNOWN | 115 | 18 | 17377 | 1707 |
BCL11B,GPR63,CYTH3,PRICKLE1,NTRK3,RNF44,SP8,GJC1,MMP15,TMEM154,SLC30A4,PMEPA1,PELI2,CHRDL1,RPL4,SMAD6,MAPK10,POU3F3 |
| 3.153e-02 | -3.46 | - | gene3d domains | 2.60.120.310 | 3 | 2 | 8148 | 867 |
MOXD1,PAM |
| 3.153e-02 | -3.46 | - | gene3d domains | 1.20.1290.10 | 3 | 2 | 8148 | 867 |
SESN2,SESN1 |
| 3.153e-02 | -3.46 | - | gene3d domains | 3.10.25.10 | 3 | 2 | 8148 | 867 |
ALDH1L2,ALDH1L1 |
| 3.153e-02 | -3.46 | - | gene3d domains | 3.30.70.890 | 3 | 2 | 8148 | 867 |
MVK,MVD |
| 3.153e-02 | -3.46 | - | gene3d domains | 2.60.120.230 | 3 | 2 | 8148 | 867 |
MOXD1,PAM |
| 3.158e-02 | -3.46 | central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-hypothalamus-glioma-astrocytoma_Grade_I | 13 | 4 | 17385 | 1698 |
RNF130,NACC2,KIAA1549,GNAI1 |
| 3.160e-02 | -3.45 | AA_permease_2 | pfam domains | PF13520 | 13 | 4 | 17054 | 1666 |
SLC7A1,SLC7A2,SLC7A11,SLC7A5 |
| 3.160e-02 | -3.45 | FA | pfam domains | PF08736 | 13 | 4 | 17054 | 1666 |
EPB41L5,EPB41L3,FARP1,FRMD5 |
| 3.162e-02 | -3.45 | carbohydrate derivative biosynthetic process | biological process | GO:1901137 | 613 | 73 | 17256 | 1658 |
CCDC126,GXYLT2,ADAL,UGT8,GALNT12,GALNT6,XYLT1,UGDH,ALG1L,MGAT5B,BCAN,TYMP,ALDOC,COG3,ENO1,GALNT18,PDGFRB,ALG10B,B3GALT1,GAPDH,GCNT2,PFKFB2,MVD,PANK1,ADCY1,PXYLP1,GPC6,ALDOA,B3GALT2,ALG11,DSEL,HS3ST3B1,HS6ST3,CRYL1,UST,ENO2,BMPR2,ST6GAL1,GALNT13,CHSY1,ADSSL1,PGAP1,GALNT1,GBGT1,PRTFDC1,MGAT1,FUT9,HS3ST5,ADCY6,ST8SIA1,B4GALT6,CHSY3,B3GLCT,MGAT4B,EDEM3,OGDHL,SDC3,ST6GALNAC3,GALNT17,GUCY1A2,GALNT14,GLCE,DPY19L2,GALNT3,PLOD2,SRD5A3,HK2,PGM2L1,HK1,CMPK2,PANK3,AMPD1,B4GALT7 |
| 3.163e-02 | -3.45 | REACTOME_SIGNALING_BY_FGFR | MSigDB lists | REACTOME_SIGNALING_BY_FGFR | 107 | 17 | 17377 | 1707 |
FGFR4,IL17RD,PDE1B,NR4A1,ADCY1,CHUK,PRKAR2B,FGF17,ITPR2,PRKCA,FGFR1,TRIB3,AKT3,PRKCD,ADCY6,SPRY2,PRKACB |
| 3.165e-02 | -3.45 | positive regulation of proteolysis | biological process | GO:0045862 | 354 | 45 | 17256 | 1658 |
LONRF1,PRKN,FN1,RNF144A,CEBPA,SNX9,F3,RNF180,PMAIP1,MYC,PRELID1,DAB2IP,PCOLCE2,ENO1,PERP,FGFR4,ATP5IF1,COL4A3,NOP53,ACVR1C,LRRK2,PACSIN3,EFNA3,PRICKLE1,RNF125,HIP1,RACK1,F12,ASPH,FAM162A,HERPUD1,GPLD1,SNCA,SMAD3,TRIB3,GSN,RNF217,BEX3,CCBE1,PLK2,ACER2,XBP1,BBC3,TNFSF15,BTRC |
| 3.168e-02 | -3.45 | GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | 53 | 10 | 17377 | 1707 |
ID3,CXCL10,MSX1,MSTN,BHLHA15,XBP1,PRICKLE1,BMP4,DDIT3,DKK1 |
| 3.175e-02 | -3.45 | TGGNNNNNNKCCAR_UNKNOWN | MSigDB lists | TGGNNNNNNKCCAR_UNKNOWN | 391 | 50 | 17377 | 1707 |
GNG12,FARP1,SYT12,STXBP6,MORC4,RASL11B,ASS1,STAT5B,SCD,ISYNA1,CREB5,IKZF2,RTN1,FOXP2,SLC22A17,RALGPS2,PCBP4,PRELID1,DAB2IP,EPHB6,SMAD6,PDGFRB,PDLIM7,RIN2,PNRC1,ADM2,PRDM13,CYTH3,NFIA,MSRB3,VIM,ROR1,ATP1B1,ZFPM2,RERE,SMAD3,LMLN,ALDOA,B3GALT2,MPP2,SEMA3C,TNFSF15,PPARGC1A,MID1,STON2,KIF1B,MLLT3,CGB2,HEY1,MEF2C |
| 3.175e-02 | -3.45 | TMEM223 (transmembrane protein 223) | protein interactions | 79064 | 31 | 7 | 17029 | 1718 |
SLC7A1,PTPRD,ATP7B,C3orf52,MME,CTH,DUSP19 |
| 3.177e-02 | -3.45 | ATPASE_E1_E2 | prosite domains | PS00154 | 36 | 8 | 12060 | 1278 |
ATP11A,ATP9A,ATP10D,ATP8A1,ATP7B,ATP2B1,ATP2B4,ATP1A3 |
| 3.186e-02 | -3.45 | SENESE_HDAC1_TARGETS_UP | MSigDB lists | SENESE_HDAC1_TARGETS_UP | 418 | 53 | 17377 | 1707 |
GNG12,FN1,ITPRIP,GPR65,ITGA6,OLAH,PRSS35,COBLL1,ADAMTS6,IGF2BP2,KIAA1217,GRPEL2,RASSF8,COL22A1,ZBTB38,CA2,SLC7A11,PPFIBP1,MYC,DSG2,STEAP3,SLC6A15,GULP1,CTTN,MET,MYO6,ERRFI1,MAST4,CEBPD,B4GALT6,VEGFC,ANTXR2,PXN,CD55,ABCC4,PNP,SLC39A8,CYB5R2,CYTH3,PHACTR2,ATP11A,ASPH,JAM3,SLC39A14,SLC7A1,DDAH1,TMEM154,FCHO2,CLDN12,AKT3,ITGA2,MAOA,GEM |
| 3.186e-02 | -3.45 | positive regulation of transcription by RNA polymerase II | biological process | GO:0045944 | 1129 | 127 | 17256 | 1658 |
CREB3L2,PRKN,ACVR1,OTX1,LILRB1,GATA3,NPM1,CTBP2,CHUK,STAT5B,CEBPA,LPIN3,IKZF2,TRPS1,SKI,EPCAM,ARHGEF10L,TLR3,EOMES,GRHL1,ACVR2A,DAB2IP,POU2F2,MET,ETV1,TLR4,POU3F3,GLI1,NKX2-1,SESN2,ATF4,MEIS2,SMAD9,NR6A1,SOX21,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,PYGO1,ATOH1,BATF,CD40,AHRR,SMAD3,CXCL10,IKZF3,HLF,INSIG1,WWTR1,NCOA7,TNFRSF1A,SOHLH2,HGF,KLF5,BMPR1A,DBP,DLX2,PPARGC1A,HOXB9,MEF2C,HEY1,BCL11B,RUNX2,BMPR2,CKAP2,ITGA6,REL,FZD8,PLAG1,APBB1,P2RY1,OVOL2,ZNF219,BMP6,MECOM,NKX6-1,ZBTB38,GATA2,MYC,BHLHA15,SREBF1,GTF2F2,TFAP2A,EBF4,LRP6,MYO6,SMAD6,GLIS1,BARX1,MED12L,CEBPD,MICAL2,SLC40A1,RAX,RHOQ,MSX1,HNF4G,STAT4,ESRRG,NR4A1,LITAF,WWC1,MAFB,ZFPM2,TAF4B,SKAP1,HOXA1,ZIC1,RERE,EBF1,CEBPB,PLAGL1,TERT,HEYL,XBP1,HOXD13,BMP4,PAX9,NKX2-8,SHOX2,SMYD3,SIX2,DDIT3,FOXA1 |
| 3.187e-02 | -3.45 | AA/rel_permease1 | interpro domains | IPR002293 | 13 | 4 | 18492 | 1811 |
SLC7A1,SLC7A2,SLC7A11,SLC7A5 |
| 3.187e-02 | -3.45 | FERM-adjacent | interpro domains | IPR014847 | 13 | 4 | 18492 | 1811 |
EPB41L5,EPB41L3,FARP1,FRMD5 |
| 3.187e-02 | -3.45 | SSD | interpro domains | IPR000731 | 13 | 4 | 18492 | 1811 |
PTCH2,DISP1,DISP2,HMGCR |
| 3.187e-02 | -3.45 | 6-PGluconate_DH-like_C_sf | interpro domains | IPR008927 | 13 | 4 | 18492 | 1811 |
EHHADH,UGDH,CRYL1,PYCR1 |
| 3.190e-02 | -3.45 | V$CHOP_01 | MSigDB lists | V$CHOP_01 | 224 | 31 | 17377 | 1707 |
CARS,NDUFA4L2,TYRO3,PCDH18,GARS,SESN2,CACNA1E,NTRK3,ATF3,PRDM1,HERPUD1,PCDH7,BCL11A,CYP51A1,CEBPB,DYRK1B,ZNF362,ABLIM1,KCTD15,KCNN2,KLF12,CACNB2,MAP2K6,MCC,JAKMIP2,DSEL,PPARGC1A,FAR2,HOXB9,NKX2-1,MEF2C |
| 3.191e-02 | -3.44 | BAE_BRCA1_TARGETS_UP | MSigDB lists | BAE_BRCA1_TARGETS_UP | 68 | 12 | 17377 | 1707 |
GSN,IDI1,ATF4,LGALS3,MSMO1,BNIP3,COL4A5,MARCKS,PRKCA,AARS,IGFBP3,ABCG1 |
| 3.191e-02 | -3.44 | WATTEL_AUTONOMOUS_THYROID_ADENOMA_UP | MSigDB lists | WATTEL_AUTONOMOUS_THYROID_ADENOMA_UP | 68 | 12 | 17377 | 1707 |
EXPH5,ENTPD1,DBN1,PRKCB,GNAO1,ST6GAL1,C3orf52,DUSP9,SNAP25,CDH2,TIAM2,QPRT |
| 3.194e-02 | -3.44 | solute:proton antiporter activity | molecular function | GO:0015299 | 19 | 5 | 17224 | 1680 |
TMCO3,SLC9C1,SLC9B1,SLC22A18,SLC9A7 |
| 3.194e-02 | -3.44 | adrenergic receptor binding | molecular function | GO:0031690 | 19 | 5 | 17224 | 1680 |
PDE4D,MAGI2,RAPGEF2,NEDD4,ADRB1 |
| 3.194e-02 | -3.44 | ephrin receptor activity | molecular function | GO:0005003 | 19 | 5 | 17224 | 1680 |
EPHA3,NTRK3,EPHB6,EPHB1,EFNA3 |
| 3.199e-02 | -3.44 | MORF_CTSB | MSigDB lists | MORF_CTSB | 173 | 25 | 17377 | 1707 |
TNIK,WISP3,GABRB2,LRP4,RNF24,PRKCA,SLC46A3,SEMA6A,GPR19,CBLN1,GPR15,PPM1E,TACC2,MAP2,ITGBL1,ADRB1,COL19A1,LRP6,ST8SIA1,TANC2,MYT1,NR3C2,SMYD3,NEB,B4GALT6 |
| 3.199e-02 | -3.44 | GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_UP | MSigDB lists | GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_UP | 173 | 25 | 17377 | 1707 |
DMXL2,ACVR1,ZNF395,RNF144A,SYBU,PHACTR2,BBS9,PGAP1,NAALADL2,DDX60L,GAS1,SMAD3,BEX4,ABLIM1,ID3,ZBTB38,RALGPS2,MSMO1,EHD3,STARD4,RAI14,FAM107B,SNX10,MID1,C15orf41 |
| 3.200e-02 | -3.44 | Bone Morphogenic Protein (BMP) Signalling and Regulation | WikiPathways | WP1425 | 12 | 4 | 5312 | 569 |
RUNX2,BMPR1A,BMPR2,SMAD6 |
| 3.201e-02 | -3.44 | podosome | cellular component | GO:0002102 | 33 | 7 | 18223 | 1724 |
SVIL,TJP1,GSN,CTTN,SH3PXD2B,PALLD,SCIN |
| 3.205e-02 | -3.44 | GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_ORGANIC_ACID_BIOSYNTHETIC_PROCESS | 250 | 34 | 17377 | 1707 |
UST,PLA2G4A,PRKAA2,GPT2,ELOVL4,ALOX5AP,ELOVL7,UGDH,OLAH,ASS1,CBS,SCD,ABAT,SLC1A3,BCAN,PHGDH,ASNS,MSMO1,KMO,GATM,SYK,CTH,FADS1,UROS,SLC27A2,ELOVL3,FASN,GSTO1,PYCR1,XBP1,DSEL,PTGES,PSPH,ACSM3 |
| 3.205e-02 | -3.44 | GO_ORGANIC_ACID_TRANSPORT | MSigDB lists | GO_ORGANIC_ACID_TRANSPORT | 250 | 34 | 17377 | 1707 |
PLA2G4A,PRKAA2,SERINC5,ACSL1,SLC6A9,SLC36A4,SLC1A3,SLC7A2,APBA1,CACNB4,SLCO3A1,SLC19A2,UNC13B,SLC7A11,SLC16A2,PPFIA2,FABP6,SERINC2,SLC6A15,SLC16A9,STXBP1,SLC3A2,ABCC4,SLC36A1,SLC27A2,ABCC2,SNAP25,SLC7A1,MFSD2A,SLC7A5,SH3BP4,SLC1A5,SLC16A10,SLC43A1 |
| 3.205e-02 | -3.44 | GO_CARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_CARBOXYLIC_ACID_BIOSYNTHETIC_PROCESS | 250 | 34 | 17377 | 1707 |
UST,PLA2G4A,PRKAA2,GPT2,ELOVL4,ALOX5AP,ELOVL7,UGDH,OLAH,ASS1,CBS,SCD,ABAT,SLC1A3,BCAN,PHGDH,ASNS,MSMO1,KMO,GATM,SYK,CTH,FADS1,UROS,SLC27A2,ELOVL3,FASN,GSTO1,PYCR1,XBP1,DSEL,PTGES,PSPH,ACSM3 |
| 3.210e-02 | -3.44 | GO_RESPONSE_TO_STARVATION | MSigDB lists | GO_RESPONSE_TO_STARVATION | 148 | 22 | 17377 | 1707 |
PRKAA2,FADS1,ATF4,BMPR2,VLDLR,LRRK2,NUAK2,ATF3,GAS6,ADSSL1,GABARAPL1,ASNS,PMAIP1,BHLHA15,XBP1,SREBF1,CADPS2,ATG5,PPARGC1A,DDIT3,RNF152,RRAGD |
| 3.210e-02 | -3.44 | GO_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MUSCLE_CELL_DIFFERENTIATION | 148 | 22 | 17377 | 1707 |
EFNB2,MSX1,MYLK3,MSTN,SMARCD3,PRICKLE1,PLCB1,CTNNA2,HOPX,DKK1,CD53,CXCL10,ID3,BHLHA15,XBP1,BMP4,CDH2,SHOX2,DDIT3,CTH,IGFBP3,MEF2C |
| 3.210e-02 | -3.44 | GSE40274_FOXP3_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 148 | 22 | 17377 | 1707 |
CXCR5,CD55,PDK1,MPP1,ST6GAL1,MCTP2,PLS1,ITPR2,ATP1B1,INPP1,FSTL5,MCOLN2,ID3,ABLIM1,TECPR1,SLC30A4,RASGRF2,TOX,TNFSF4,RAPGEF5,DIRC2,SLC43A1 |
| 3.218e-02 | -3.44 | GO_GDP_METABOLIC_PROCESS | MSigDB lists | GO_GDP_METABOLIC_PROCESS | 13 | 4 | 17377 | 1707 |
DLG2,MPP1,MAGI3,MPP2 |
| 3.218e-02 | -3.44 | GO_NEUROBLAST_DIVISION | MSigDB lists | GO_NEUROBLAST_DIVISION | 13 | 4 | 17377 | 1707 |
NUMBL,DOCK7,FGF13,FGFR1 |
| 3.218e-02 | -3.44 | BIOCARTA_AGPCR_PATHWAY | MSigDB lists | BIOCARTA_AGPCR_PATHWAY | 13 | 4 | 17377 | 1707 |
PRKAR2B,PRKCA,PRKCB,PRKACB |
| 3.218e-02 | -3.44 | GO_PLATELET_ALPHA_GRANULE_MEMBRANE | MSigDB lists | GO_PLATELET_ALPHA_GRANULE_MEMBRANE | 13 | 4 | 17377 | 1707 |
PHACTR2,ITGB3,PCDH7,SNCA |
| 3.218e-02 | -3.44 | GO_RAC_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | GO_RAC_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 13 | 4 | 17377 | 1707 |
VAV3,FARP1,DOCK2,SPATA13 |
| 3.218e-02 | -3.44 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | MSigDB lists | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | 13 | 4 | 17377 | 1707 |
NRP1,SEMA3A,FES,PLXNA2 |
| 3.218e-02 | -3.44 | GO_NEURONAL_STEM_CELL_DIVISION | MSigDB lists | GO_NEURONAL_STEM_CELL_DIVISION | 13 | 4 | 17377 | 1707 |
NUMBL,DOCK7,FGF13,FGFR1 |
| 3.218e-02 | -3.44 | GO_POSITIVE_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | 13 | 4 | 17377 | 1707 |
GPR37,GATA3,ABAT,PRKCD |
| 3.218e-02 | -3.44 | GO_POSITIVE_REGULATION_OF_MAST_CELL_DEGRANULATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MAST_CELL_DEGRANULATION | 13 | 4 | 17377 | 1707 |
FGR,SYK,VAMP8,GAB2 |
| 3.218e-02 | -3.44 | GO_LOW_DENSITY_LIPOPROTEIN_RECEPTOR_ACTIVITY | MSigDB lists | GO_LOW_DENSITY_LIPOPROTEIN_RECEPTOR_ACTIVITY | 13 | 4 | 17377 | 1707 |
LRP6,LRP12,VLDLR,LDLR |
| 3.218e-02 | -3.44 | GO_RESPONSE_TO_STIMULUS_INVOLVED_IN_REGULATION_OF_MUSCLE_ADAPTATION | MSigDB lists | GO_RESPONSE_TO_STIMULUS_INVOLVED_IN_REGULATION_OF_MUSCLE_ADAPTATION | 13 | 4 | 17377 | 1707 |
SCN5A,FBXO32,PPARGC1A,NEDD4 |
| 3.218e-02 | -3.44 | WU_HBX_TARGETS_3_DN | MSigDB lists | WU_HBX_TARGETS_3_DN | 13 | 4 | 17377 | 1707 |
PAK1,GAS6,PMAIP1,GSTM4 |
| 3.218e-02 | -3.44 | RODRIGUES_THYROID_CARCINOMA_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_UP | 13 | 4 | 17377 | 1707 |
DISP1,RPS23,FKBP11,GNAI1 |
| 3.218e-02 | -3.44 | GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | MSigDB lists | GO_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL | 13 | 4 | 17377 | 1707 |
PKP2,RYR2,SCN5A,ANK2 |
| 3.218e-02 | -3.44 | GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS | 13 | 4 | 17377 | 1707 |
COL18A1,BMP4,CD40,XBP1 |
| 3.218e-02 | -3.44 | GO_CELL_MIGRATION_IN_HINDBRAIN | MSigDB lists | GO_CELL_MIGRATION_IN_HINDBRAIN | 13 | 4 | 17377 | 1707 |
RBFOX2,CTNNA2,RERE,PLXNA2 |
| 3.218e-02 | -3.44 | GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_MAST_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE | 13 | 4 | 17377 | 1707 |
FGR,SYK,VAMP8,GAB2 |
| 3.218e-02 | -3.44 | GO_POSITIVE_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS | 13 | 4 | 17377 | 1707 |
PPARGC1A,BMP6,ABCG1,SREBF1 |
| 3.219e-02 | -3.44 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | 329 | 43 | 17377 | 1707 |
GPT2,ACSL1,TCTN2,RNF144A,LDLR,APBB1,DHCR24,TDRKH,SCD,ISYNA1,LACC1,NHP2,KIF21B,SEL1L3,NCS1,ARHGAP44,CYP51A1,IDI1,HMGCS1,MSMO1,MYC,PTPRE,IL1RAP,DBN1,PDK1,SLC27A2,FASN,TAF4B,HERPUD1,CENPV,SFXN1,SLC39A14,ARHGAP21,INSIG1,EIF4EBP1,GNB4,PELI2,XBP1,SLC7A5,SQLE,DISP2,RNF122,DHCR7 |
| 3.220e-02 | -3.44 | oligoastrocytoma_Grade_III | COSMIC cancer mutations | oligoastrocytoma_Grade_III | 269 | 36 | 17385 | 1698 |
ACVR1,CELSR1,EHHADH,FAM131C,PLEKHA5,SYT12,GALNT6,XYLT1,ADAMTS6,DENND3,PPP2R3A,PCDH7,SPEG,PDZD8,FRY,POU5F1B,PDE10A,MAP7,GRIP1,SP140,MYO6,KIAA1549,FES,SMAD9,RNF145,OGDHL,OBSCN,RYR2,C1R,PYGO1,DSP,GPC6,TBC1D2,EDA,TERT,TLL2 |
| 3.220e-02 | -3.44 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN | 190 | 27 | 17377 | 1707 |
RGS16,ACSL1,PDK1,TUBA1A,SLC39A8,KIF5C,STEAP1,DDIT4,EPB41L3,MAGEA12,MSC,HLF,SLC30A4,PLOD2,GBP1,P4HA2,INPP4B,MCC,RAB31,SFMBT1,PDE4D,PTPRCAP,IQSEC2,FAM155A,CKAP4,STOM,CYP1B1 |
| 3.220e-02 | -3.44 | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | 190 | 27 | 17377 | 1707 |
MICAL2,EIF4E3,ANKRD13D,ALOX5AP,IL15,PLEKHA5,ARL15,CYTH3,HIP1,PHACTR2,LCP2,ATP10D,GABARAPL1,HEG1,KIAA1671,FCHO2,PIK3AP1,GNAO1,EHD3,ABI3,TNFRSF1A,BCL6,TOX,BMPR1A,PPP2R2B,SLC1A5,SNX10 |
| 3.220e-02 | -3.44 | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | 190 | 27 | 17377 | 1707 |
EDA2R,FLVCR2,NR6A1,GABRB2,SYBU,LACC1,BATF,DENND3,CBLN1,SPIRE1,SYDE2,QPRT,MKX,GJC1,SLC7A1,IFT81,UNC13B,GRHL1,RND3,ABI3BP,CACNB2,BMP1,HK2,FAM84B,NCEH1,RNF157,PTGES |
| 3.220e-02 | -3.44 | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_DN | MSigDB lists | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_DN | 190 | 27 | 17377 | 1707 |
DLGAP1,GCA,VNN2,DISC1,ALDH2,DUSP8,ARHGEF11,PLXNA2,SORBS3,PRDM1,ACVR2B,CDC42BPA,FGFR1,DDIT4,PCDH7,BCL11A,CD37,FAM189A1,FAM168A,MCC,PRKG2,NXPH4,MARCH3,KLF5,CDH2,ZFP36L2,DDIT3 |
| 3.220e-02 | -3.44 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 190 | 27 | 17377 | 1707 |
CARS,RIN2,UGT8,SKAP2,CEBPA,MARS,COLEC10,PRKCA,DOK5,PLS3,GPR15,CPVL,PRCP,ALDOC,PLK2,INPP4B,NDUFB8,ZBTB20,TOX,PCK2,PTPRCAP,IQSEC2,NKX2-8,DHCR7,GATM,ZNF629,SLC43A1 |
| 3.220e-02 | -3.44 | GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_DN | MSigDB lists | GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_DN | 190 | 27 | 17377 | 1707 |
GPT2,GNG12,INPPL1,GARS,GATA3,MARS,CTTNBP2NL,CHAC1,MGAT5B,INPP1,SPATA7,C9orf116,SCIN,TRIM9,VPS37D,HMGCS1,RNF217,SLC7A5,CHRDL1,ZDHHC23,COG3,PCK2,SCN2A,TMEM120B,OSBPL6,SEMA6C,TBC1D8 |
| 3.220e-02 | -3.44 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | 190 | 27 | 17377 | 1707 |
TRPM4,RGS16,EVL,ENO2,SIDT1,ARHGEF11,RECK,MCTP2,MCOLN3,PRRG1,FAM117B,HERC6,ABHD6,DOCK2,RERE,HOPX,PTPRC,FOXP2,GSN,SEMA4F,GPR155,PJA1,ETV1,CTTNBP2,ENO1,KIF1B,AMPD1 |
| 3.220e-02 | -3.44 | GSE14350_TREG_VS_TEFF_DN | MSigDB lists | GSE14350_TREG_VS_TEFF_DN | 190 | 27 | 17377 | 1707 |
MICAL2,UGT8,MARK1,SOX21,ALDH1L2,CHAC1,EPHB1,BCAN,CBLN1,CYP26A1,NEO1,SPEG,SH3GL2,SOAT2,NOVA2,EIF4EBP1,GNAO1,REEP1,MAP9,ITGB3,MPP2,BEND4,SH3PXD2B,THOC3,KCTD1,FES,DENND5B |
| 3.220e-02 | -3.44 | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 190 | 27 | 17377 | 1707 |
AVPI1,ID1,RNF144A,REL,ATP9A,CAP2,YPEL2,RASA3,ADAMTS6,STAT5B,SATB1,DDR1,UBTD2,QPRT,SKI,SCIN,RALGPS2,PMEPA1,MAP7,PTPRS,ADCY6,SERPINI1,ST8SIA1,TMEM120B,RNF157,IGSF3,ABCG1 |
| 3.220e-02 | -3.44 | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | MSigDB lists | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | 190 | 27 | 17377 | 1707 |
MPZL3,MAN2B2,GPT2,LONRF1,PDLIM7,MPP1,PANK1,LRMP,PHACTR2,CHSY1,BATF,IKZF2,FAM162A,ARHGAP21,GRHL1,SH3RF1,ALDOC,PPFIBP1,EHD3,TMEM86A,MPP2,BCL6,SMTN,SLC22A15,NRP1,RNF157,TBC1D4 |
| 3.220e-02 | -3.44 | GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_DN | 190 | 27 | 17377 | 1707 |
INPPL1,ALDH2,SCAMP1,FN1,IL15,ITGA6,EPS8,LITAF,ASS1,NPM1,PDE8A,GSTO1,PRDM1,ATP11A,ADSSL1,NEDD4,DDIT4,EPCAM,SFXN1,MCOLN2,IGF1R,MYC,ZNF808,ZBTB20,SH3BGRL2,ENO1,SMPDL3A |
| 3.222e-02 | -3.44 | sarcolemma | cellular component | GO:0042383 | 128 | 19 | 18223 | 1724 |
SCN5A,COL6A2,BVES,ANK2,RYR2,OBSCN,ATP1B1,KCND3,SNTB1,NOS1AP,POPDC3,SCN1B,CACNB2,PEMT,AHNAK2,SCN2A,CDH2,CACNA2D1,ATP2B4 |
| 3.232e-02 | -3.43 | phosphoric diester hydrolase activity | molecular function | GO:0008081 | 92 | 15 | 17224 | 1680 |
ENPP1,PDE1B,ENPP6,PDE10A,GDPD1,PDE8A,NOTUM,PLD1,PDE4D,PLCB1,GDPD5,SMPDL3B,SMPDL3A,CHRM3,GPLD1 |
| 3.234e-02 | -3.43 | skin-foot-malignant_melanoma | COSMIC cancer mutations | skin-foot-malignant_melanoma | 84 | 14 | 17385 | 1698 |
TMEM132B,PTPRC,PTPRJ,PTPRD,DCC,ADAMTS3,PTPN13,PTPN21,PTPRS,PTPRN2,TNS1,PTPRE,KHDRBS2,CHRM3 |
| 3.234e-02 | -3.43 | Glutathione-S-Trfase_C-like | interpro domains | IPR010987 | 32 | 7 | 18492 | 1811 |
GSTM3,MARS,GDAP1,GSTO1,GSTM2,GSTO2,GSTM4 |
| 3.256e-02 | -3.42 | V$ICSBP_Q6 | MSigDB lists | V$ICSBP_Q6 | 233 | 32 | 17377 | 1707 |
MXI1,CCDC148,SORBS1,KLHL13,TNFSF13B,OTX1,TNFRSF19,IKZF2,HMCN1,SP8,FRY,DNAH6,ZIC5,KCNMB3,MPDZ,SP140,VGLL4,FES,MEIS2,MSX1,LRMP,SATB2,BCL11A,TSKU,ENTPD1,DAGLA,MAP2K6,DLG2,TNFSF15,PPARGC1A,TNFRSF17,FNBP1L |
| 3.267e-02 | -3.42 | GO_REGULATION_OF_BODY_FLUID_LEVELS | MSigDB lists | GO_REGULATION_OF_BODY_FLUID_LEVELS | 491 | 61 | 17377 | 1707 |
TYRO3,BTC,DOCK1,UBASH3B,VAMP8,GATA3,HBE1,STAT5B,ITPR2,GAS6,ABAT,P2RY1,LCP2,PRKCA,DDR1,F3,SLC7A11,GATA2,EHD3,PRKCD,ITGB3,PRKG1,ADCY6,PROS1,TLR4,STXBP1,SYK,ZNF385A,PRKACB,CHRM3,DOCK8,NOS3,VAV3,HBG2,CSN2,PTPN6,ADCY1,PRKCQ,PRKAR2B,F12,ZFPM2,CD40,C4BPB,HEG1,ENTPD1,HPSE,PRKCB,PRCP,ATP7B,WFS1,XBP1,ITGA2,PAM,HK2,OXTR,ATG5,TRPC3,TC2N,DOCK6,SFN,DOCK9 |
| 3.268e-02 | -3.42 | Wnt Signaling Pathway | WikiPathways | WP428 | 70 | 13 | 5312 | 569 |
PRKCB,FZD8,MYC,PRKCD,LDLR,LRP6,WNT11,PRKCQ,ROR1,PRKCA,MAPK10,KREMEN1,FZD1 |
| 3.270e-02 | -3.42 | ovulation cycle | biological process | GO:0042698 | 62 | 11 | 17256 | 1658 |
TYRO3,ROBO2,MSTN,FZD4,MAP2K6,PAM,STAT5B,OXTR,PLEKHA1,SLIT2,NOS3 |
| 3.273e-02 | -3.42 | RGS_sf | interpro domains | IPR036305 | 39 | 8 | 18492 | 1811 |
RGS17,RGS16,GRK6,RGS7,ARHGEF11,GRK3,RGS10,RGS20 |
| 3.273e-02 | -3.42 | RA_dom | interpro domains | IPR000159 | 39 | 8 | 18492 | 1811 |
RASSF8,RIN2,ARAP2,GRB14,MYO10,RAPGEF2,GRB10,RADIL |
| 3.274e-02 | -3.42 | GO_REGULATION_OF_MYOBLAST_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_MYOBLAST_DIFFERENTIATION | 46 | 9 | 17377 | 1707 |
ID3,CXCL10,MSTN,PRICKLE1,BMP4,PLCB1,DDIT3,IGFBP3,MEF2C |
| 3.274e-02 | -3.42 | GO_COMPLEMENT_ACTIVATION | MSigDB lists | GO_COMPLEMENT_ACTIVATION | 46 | 9 | 17377 | 1707 |
CD55,CFH,CFHR1,C4A,CR2,C1R,SUSD4,COLEC10,C4BPB |
| 3.274e-02 | -3.42 | BIOCARTA_KERATINOCYTE_PATHWAY | MSigDB lists | BIOCARTA_KERATINOCYTE_PATHWAY | 46 | 9 | 17377 | 1707 |
PRKCQ,CHUK,MAPK13,CEBPA,PRKCA,PRKCB,MAP2K6,PRKCD,TNFRSF1A |
| 3.274e-02 | -3.42 | chr6q25 | MSigDB lists | chr6q25 | 46 | 9 | 17377 | 1707 |
RGS17,CNKSR3,AGPAT4,PLEKHG1,IPCEF1,ZDHHC14,SNX9,TIAM2,ULBP1 |
| 3.274e-02 | -3.42 | GO_NEGATIVE_REGULATION_OF_GTPASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_GTPASE_ACTIVITY | 46 | 9 | 17377 | 1707 |
TNK2,IPO5,LRRK2,SH3BP4,PTPRN2,ARL2,DAB2IP,SPRY2,SLIT2 |
| 3.279e-02 | -3.42 | GO_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 165 | 24 | 17377 | 1707 |
PAK1,FER,EVL,ID1,MYLK3,DSTN,GPR65,ARL2,SORBS3,PRKCQ,WNT11,NTRK3,PFN2,SPIRE1,BAIAP2,SCIN,SMAD3,GSN,PPM1E,NCKAP1L,WIPF3,CTTN,TPM1,FES |
| 3.279e-02 | -3.42 | GO_CILIUM_ORGANIZATION | MSigDB lists | GO_CILIUM_ORGANIZATION | 165 | 24 | 17377 | 1707 |
B9D1,INTU,DISC1,TMEM67,ABCC4,TCTN2,CELSR3,SPATA6,TTC30A,BBS9,PIBF1,TTC30B,ARMC4,IFT81,ABLIM1,TMEM237,LRRC6,EHD3,WDR19,DYNC2LI1,DYNC2H1,DNAH5,SNX10,FNBP1L |
| 3.280e-02 | -3.42 | NAF1 (nuclear assembly factor 1 ribonucleoprotein) | protein interactions | 92345 | 74 | 13 | 17029 | 1718 |
EPB41L5,EPB41L3,EDA,BCHE,RBFOX2,MPP1,FAM168A,PTPN21,C1orf226,NHP2,SNX9,NCS1,NOS1AP |
| 3.281e-02 | -3.42 | LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES | MSigDB lists | LEIN_LOCALIZED_TO_PROXIMAL_DENDRITES | 32 | 7 | 17377 | 1707 |
KIF5C,NECAB2,MAP1A,MAP2,ANK2,DNAJC6,MAP1B |
| 3.281e-02 | -3.42 | GO_PHOSPHATIDYLSERINE_BINDING | MSigDB lists | GO_PHOSPHATIDYLSERINE_BINDING | 32 | 7 | 17377 | 1707 |
MARCKS,MARK1,GAS6,FCHO2,RASGRP1,OSBPL5,SCIN |
| 3.281e-02 | -3.42 | PI Metabolism | REACTOME pathways | R-HSA-1483255 | 79 | 13 | 10287 | 971 |
INPPL1,PLEKHA8,ENPP6,PTPN13,PLEKHA5,GDPD1,TNFAIP8L2,INPP4B,INPP5F,PIK3C2B,PLEKHA1,FIG4,GDPD5 |
| 3.281e-02 | -3.42 | MODULE_33 | MSigDB lists | MODULE_33 | 365 | 47 | 17377 | 1707 |
UGT8,IGFBP6,ITGA6,ARHGAP22,BIK,SELL,ASS1,MAPK4,INPP1,PFN2,PHLDA2,HMGCS1,RPS6KA2,GATA2,CFHR1,DSG2,BCL6,MAP7,ACTA2,HRK,LMAN2,MARCKS,NEB,ZFP36L2,GLI1,NKX2-1,FGFR4,PRAME,ITGB7,FEZ1,CR2,ASPH,SMAD3,CXCL10,PLOD2,PTK7,FAT1,CCNA1,HK2,TNFRSF1A,PTPRS,BBC3,MAOA,APBA2,MAPK10,CACNA2D1,CSRP2 |
| 3.281e-02 | -3.42 | GO_NITRIC_OXIDE_SYNTHASE_BINDING | MSigDB lists | GO_NITRIC_OXIDE_SYNTHASE_BINDING | 19 | 5 | 17377 | 1707 |
SCN5A,DNM3,CDH2,NOS1AP,ATP2B4 |
| 3.281e-02 | -3.42 | KAMIKUBO_MYELOID_MN1_NETWORK | MSigDB lists | KAMIKUBO_MYELOID_MN1_NETWORK | 19 | 5 | 17377 | 1707 |
SGK1,MN1,MLLT3,CRIP2,MTUS1 |
| 3.281e-02 | -3.42 | GO_CELLULAR_SODIUM_ION_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_SODIUM_ION_HOMEOSTASIS | 19 | 5 | 17377 | 1707 |
SGK1,ATP1B1,SGK2,ATP1A3,SGK3 |
| 3.281e-02 | -3.42 | GO_FILAMENTOUS_ACTIN | MSigDB lists | GO_FILAMENTOUS_ACTIN | 19 | 5 | 17377 | 1707 |
FERMT2,PAK1,MYO6,TPM1,RAC3 |
| 3.281e-02 | -3.42 | GO_1_PHOSPHATIDYLINOSITOL_BINDING | MSigDB lists | GO_1_PHOSPHATIDYLINOSITOL_BINDING | 19 | 5 | 17377 | 1707 |
SNX10,SNX9,PLEKHA5,ZFYVE9,SCIN |
| 3.281e-02 | -3.42 | GO_EPHRIN_RECEPTOR_ACTIVITY | MSigDB lists | GO_EPHRIN_RECEPTOR_ACTIVITY | 19 | 5 | 17377 | 1707 |
EPHA3,NTRK3,EPHB6,EPHB1,EFNA3 |
| 3.281e-02 | -3.42 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_NITROGENOUS_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_NITROGENOUS_GROUPS | 19 | 5 | 17377 | 1707 |
GPT2,GAPDH,ABAT,AADAT,GATM |
| 3.281e-02 | -3.42 | GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_REGULATION_OF_THE_RELEASE_OF_SEQUESTERED_CALCIUM_ION | MSigDB lists | GO_REGULATION_OF_CARDIAC_MUSCLE_CONTRACTION_BY_REGULATION_OF_THE_RELEASE_OF_SEQUESTERED_CALCIUM_ION | 19 | 5 | 17377 | 1707 |
RYR2,GSTO1,GSTM2,ASPH,ANK2 |
| 3.281e-02 | -3.42 | GO_PHOSPHATIDYLINOSITOL_4_PHOSPHATE_BINDING | MSigDB lists | GO_PHOSPHATIDYLINOSITOL_4_PHOSPHATE_BINDING | 19 | 5 | 17377 | 1707 |
DAB2IP,SH3PXD2B,PLEKHA8,PLEKHA5,OSBPL5 |
| 3.281e-02 | -3.42 | GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION | MSigDB lists | GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_MEMBRANE_REPOLARIZATION | 19 | 5 | 17377 | 1707 |
SCN5A,SCN1B,ANK2,NOS1AP,CACNA2D1 |
| 3.281e-02 | -3.42 | GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_CARDIAC_MUSCLE_CELL_DIFFERENTIATION | 19 | 5 | 17377 | 1707 |
EFNB2,PRICKLE1,BMP4,MEF2C,DKK1 |
| 3.281e-02 | -3.42 | NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_UP | MSigDB lists | NIELSEN_GIST_AND_SYNOVIAL_SARCOMA_UP | 19 | 5 | 17377 | 1707 |
DPP10,COL4A5,TOX,BMP4,BCHE |
| 3.281e-02 | -3.42 | MCCABE_HOXC6_TARGETS_DN | MSigDB lists | MCCABE_HOXC6_TARGETS_DN | 19 | 5 | 17377 | 1707 |
PAK1,ERRFI1,GAS2L3,APBB1,CNTN1 |
| 3.281e-02 | -3.42 | SESTO_RESPONSE_TO_UV_C3 | MSigDB lists | SESTO_RESPONSE_TO_UV_C3 | 19 | 5 | 17377 | 1707 |
ATF3,PMAIP1,RND3,PHLDA2,DUSP1 |
| 3.284e-02 | -3.42 | regulation of leukocyte differentiation | biological process | GO:1902105 | 256 | 34 | 17256 | 1658 |
LGALS3,IL15,UBASH3B,LILRB1,GATA3,STAT5B,GAS6,PRKCA,SPINK5,TLR3,CA2,GATA2,MYC,PRELID1,BCL6,TOX,TLR4,TESPA1,SYK,ZFP36L2,RASGRP1,PNP,PTPN6,MAFB,PRDM1,CEBPB,IKZF3,FBN1,NCKAP1L,CSF1,XBP1,BMP4,TNFSF4,TESC |
| 3.285e-02 | -3.42 | GO_ION_HOMEOSTASIS | MSigDB lists | GO_ION_HOMEOSTASIS | 555 | 68 | 17377 | 1707 |
GRIK2,ITPR2,CACNB4,SLC9A7,SLC22A17,CNNM2,TRPC1,STEAP3,CD55,KLHL3,SLC39A8,SFXN4,ANK2,JPH1,LRRK2,ATOX1,ACO1,SLC25A28,ABCC2,RAB38,ATP1B1,CD40,SGK2,SNCA,SFXN1,SLC39A14,ENPP1,PRKCB,WFS1,ATP7B,BDH2,BBC3,OXTR,PRKAA2,LPAR2,ATP6V1E2,BTBD9,P2RY1,SFXN3,BMP6,MCU,NEO1,SLC30A4,CA2,GATA2,MYC,STC2,SGK3,LRP6,SGK1,ATP2B1,TRPM4,FGFR4,SLC40A1,DISC1,RASA3,RYR2,CLN5,STEAP1,HERPUD1,PTPRC,XBP1,DDIT3,CACNA2D1,ATP2B4,ABCG1,TPT1,ATP1A3 |
| 3.289e-02 | -3.41 | Direct p53 effectors | Pathway Interaction DB | p53downstreampathway | 132 | 24 | 2226 | 278 |
TGFA,BNIP3L,COL18A1,ATF3,CCNG1,TNFRSF10C,PRDM1,SESN1,DKK1,DDIT4,PMAIP1,PCBP4,BCL6,BBC3,HGF,STEAP3,MET,FOXA1,ZNF385A,SFN,SNAI2,PERP,DUSP1,IGFBP3 |
| 3.292e-02 | -3.41 | basement membrane collagen trimer | cellular component | GO:0098651 | 8 | 3 | 18223 | 1724 |
COL4A5,COL4A3,COL4A4 |
| 3.292e-02 | -3.41 | Lewy body | cellular component | GO:0097413 | 8 | 3 | 18223 | 1724 |
PRKN,ATF4,HERPUD1 |
| 3.300e-02 | -3.41 | organic anion transport | biological process | GO:0015711 | 419 | 52 | 17256 | 1658 |
PLA2G4A,PRKAA2,SERINC5,ACSL1,SLC6A9,ATP9A,ATP8A1,LDLR,SLC36A4,SLC7A2,SLC1A3,APBA1,SLC19A2,SLCO3A1,CA2,UNC13B,SLC7A11,SLC22A17,SLC16A2,PPFIA2,FABP6,PRELID2,PRELID1,SERINC2,SLC16A9,SLC6A15,SLCO4C1,STXBP1,PLTP,SLC3A2,ABCC4,SLC27A2,SLC36A1,CYB5R2,PPFIA4,ABCC2,NPC2,SNAP25,ATP11A,ATP10D,CA13,SLC7A1,MFSD2A,OSBPL5,SH3BP4,SLC7A5,SLCO5A1,SLC22A15,SLC1A5,SLC16A10,ABCG1,SLC43A1 |
| 3.302e-02 | -3.41 | WONG_ENDMETRIUM_CANCER_DN | MSigDB lists | WONG_ENDMETRIUM_CANCER_DN | 76 | 13 | 17377 | 1707 |
EFEMP1,SYNPO2,TMEM132C,PLEKHH2,IGFBP6,FBN1,CCBE1,XYLT1,TRPC1,HGF,GAS6,COL14A1,MME |
| 3.310e-02 | -3.41 | GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_DN | 182 | 26 | 17377 | 1707 |
MSX1,PLSCR4,BMPR2,GATA3,SELL,HERC5,SLC25A28,ATF3,SPATS2L,HERC6,DSP,CBLN1,PCLO,HEG1,BATF3,ISG20,CXCL10,ZNF93,TLR3,FLRT3,DLG2,KIAA0408,DLX2,SP140L,IGFBP3,LAMP3 |
| 3.310e-02 | -3.41 | GSE42724_MEMORY_VS_B1_BCELL_DN | MSigDB lists | GSE42724_MEMORY_VS_B1_BCELL_DN | 182 | 26 | 17377 | 1707 |
FADS1,LONRF1,PNRC1,STAT4,ELOVL7,LDLR,ARID5B,TTYH2,AK4,C1R,SCD,CD40,HOPX,ISG20,MCOLN2,IDI1,SLC7A11,MSMO1,SCN1B,GBP1,SLC2A6,ENO1,DHCR7,RASGRP1,PARP9,HMGCR |
| 3.310e-02 | -3.41 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_DN | 182 | 26 | 17377 | 1707 |
PFKFB4,PAK1,VAV3,AVPI1,FN1,SKAP2,MPP1,LPCAT2,UBASH3B,BLVRB,VAMP8,TMEM170B,FAM13A,UCHL3,ABHD6,CHN2,PRCP,FAM168A,PLXDC2,SRD5A3,GAS2L3,EEPD1,KIAA0513,DISP1,NCEH1,TNFRSF11A |
| 3.310e-02 | -3.41 | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 182 | 26 | 17377 | 1707 |
NMNAT3,EVL,PDK1,GALNT6,IGF2BP2,MFSD6,SATB1,TBC1D16,NUDT12,HECTD2,SLC7A1,ABLIM1,ZNF438,NACC2,P4HA2,EHD3,ITGB3,WWTR1,SGK1,HS3ST3B1,FAM84B,ST8SIA1,RNF122,DIRC2,PRKACB,B4GALT7 |
| 3.310e-02 | -3.41 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | 182 | 26 | 17377 | 1707 |
SERINC5,TNIK,MXI1,PXN,CFH,FNDC3A,FAM13A,RNF44,PFN2,MBNL2,JAM3,IRS2,RASSF8,PRKCB,TSC22D1,KIAA0513,SGK1,PIK3C2B,APBA2,NR3C2,ZFP36L2,CKAP4,ATP2B1,PHC1,DUSP1,STOM |
| 3.310e-02 | -3.41 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP | 182 | 26 | 17377 | 1707 |
DZANK1,MID2,VAV3,UGT8,CELSR1,PNRC1,RASAL2,TMEM43,CHCHD7,STAT4,SELL,KIF5C,PEX5L,FAM198B,SESN1,PLCB1,SLC46A3,EPCAM,FKBP9,EIF1,TSC22D1,PCOLCE2,ALPK1,ZFP36L2,CRYL1,DUSP1 |
| 3.310e-02 | -3.41 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | 182 | 26 | 17377 | 1707 |
TUBA1A,LDLR,TTYH2,LRRC49,CHUK,NPC2,PLEKHA1,C4orf19,ADSSL1,IL18R1,CENPV,PLEKHB1,EPCAM,RSL24D1,HMGCS1,IDI1,ALDOA,TRIM3,POF1B,SQLE,TUFT1,HK1,PTPRE,CKAP4,CYP1B1,PARP9 |
| 3.310e-02 | -3.41 | GSE17721_0.5H_VS_12H_LPS_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_12H_LPS_BMDC_UP | 182 | 26 | 17377 | 1707 |
MYCBP2,EHHADH,ELOVL7,LRMP,TTYH2,HIP1,SORBS3,FAM198B,NHP2,FAM81A,CANX,CENPV,FKBP11,DHX32,ENPP1,RPL28,PEMT,ALDOA,STARD4,RAB31,OPN3,RGS10,TRIM3,LAPTM4B,TSPAN13,CSRP2 |
| 3.310e-02 | -3.41 | GSE21379_TFH_VS_NON_TFH_SAP_KO_CD4_TCELL_UP | MSigDB lists | GSE21379_TFH_VS_NON_TFH_SAP_KO_CD4_TCELL_UP | 182 | 26 | 17377 | 1707 |
EPB41L5,TNK2,TBC1D8B,CYTH3,BLVRB,GDPD1,ADD2,STRADB,CCNG1,ZDHHC14,TEX9,CA13,EPDR1,BEX4,ZNF266,CA2,PRCP,CECR2,GPR155,GSTM3,GRB10,FHIT,HK1,CHRM3,SLC43A1,STOM |
| 3.310e-02 | -3.41 | GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_UP | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_UP | 182 | 26 | 17377 | 1707 |
USP2,RHOQ,RNF144A,RBFOX2,ST6GAL1,MYO1B,SELL,KCTD12,CDC42BPA,GUCY1A2,PALLD,MBNL2,TPD52L1,PCLO,CHST10,EPB41L3,KCNS3,MPPED2,LIN7A,SEMA3C,GFI1,SHOX2,PTPRE,MID1,SNX7,PCSK5 |
| 3.314e-02 | -3.41 | GNA12 (G protein subunit alpha 12) | protein interactions | 2768 | 38 | 8 | 17029 | 1718 |
ARHGEF28,ARHGEF11,PRKCB,PRKCD,LRRK2,PRKCA,CDH2,TSHR |
| 3.314e-02 | -3.41 | TMEM231 (transmembrane protein 231) | protein interactions | 79583 | 38 | 8 | 17029 | 1718 |
EPHA3,B9D1,TCTN2,LAPTM4B,PTPRS,RNF130,NDFIP2,NCEH1 |
| 3.314e-02 | -3.41 | EMC1 (ER membrane protein complex subunit 1) | protein interactions | 23065 | 38 | 8 | 17029 | 1718 |
TMEM67,TMEM237,TCTN2,UBAC2,EDEM3,TSC22D1,CANX,ENO1 |
| 3.322e-02 | -3.40 | GO_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | MSigDB lists | GO_POSITIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 132 | 20 | 17377 | 1707 |
PAK1,TNIK,EDA2R,FZD4,FZD8,PKN1,PLCB1,TNFRSF19,TPD52L1,TLR6,TLR3,ERN1,DUSP19,DAB2IP,TLR4,TNFRSF11A,MID1,SYK,RASGRP1,HMGCR |
| 3.324e-02 | -3.40 | KEGG_LYSINE_DEGRADATION | MSigDB lists | KEGG_LYSINE_DEGRADATION | 39 | 8 | 17377 | 1707 |
NSD1,ALDH2,SETDB2,EHHADH,AADAT,AASS,PLOD2,OGDHL |
| 3.324e-02 | -3.40 | KORKOLA_EMBRYONAL_CARCINOMA_UP | MSigDB lists | KORKOLA_EMBRYONAL_CARCINOMA_UP | 39 | 8 | 17377 | 1707 |
GAPDH,ENO2,PTPN6,TNFRSF1A,AK4,LRP6,GABARAPL1,PHC1 |
| 3.324e-02 | -3.40 | GO_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | MSigDB lists | GO_REGULATION_OF_CELL_ADHESION_MEDIATED_BY_INTEGRIN | 39 | 8 | 17377 | 1707 |
NCKAP1L,RAC3,TESC,SYK,ACER2,PTPN6,SNAI2,CYP1B1 |
| 3.324e-02 | -3.40 | KORKOLA_SEMINOMA_UP | MSigDB lists | KORKOLA_SEMINOMA_UP | 39 | 8 | 17377 | 1707 |
LRP6,AK4,GAPDH,ENO2,TSPAN9,PTPN6,PHC1,GABARAPL1 |
| 3.324e-02 | -3.40 | KAMMINGA_SENESCENCE | MSigDB lists | KAMMINGA_SENESCENCE | 39 | 8 | 17377 | 1707 |
ARHGEF10L,ID1,GNAO1,THBS4,TCEA3,ARHGAP28,FHIT,RABAC1 |
| 3.324e-02 | -3.40 | GOBERT_CORE_OLIGODENDROCYTE_DIFFERENTIATION | MSigDB lists | GOBERT_CORE_OLIGODENDROCYTE_DIFFERENTIATION | 39 | 8 | 17377 | 1707 |
MAP7,UGT8,CCNG1,ABAT,SORBS1,LRRN1,IKZF5,SLC25A27 |
| 3.333e-02 | -3.40 | miRs in Muscle Cell Differentiation | WikiPathways | WP2012 | 36 | 8 | 5312 | 569 |
PRKCB,PRKCD,MEF2B,PRKAR2B,PRKCQ,PRKCA,PRKACB,MEF2C |
| 3.347e-02 | -3.40 | sarcoplasm | cellular component | GO:0016528 | 71 | 12 | 18223 | 1724 |
GSN,GSTM2,THBS4,JPH1,RYR2,RASD1,ITPR2,AGL,ASPH,CACNA2D1,NOS1AP,MEF2C |
| 3.352e-02 | -3.40 | endochondral ossification | biological process | GO:0001958 | 26 | 6 | 17256 | 1658 |
INPPL1,RUNX2,BMP4,BMP6,MMP16,MEF2C |
| 3.352e-02 | -3.40 | striated muscle adaptation | biological process | GO:0014888 | 26 | 6 | 17256 | 1658 |
GSN,INPP5F,PPARGC1A,IL15,MSTN,MEF2C |
| 3.352e-02 | -3.40 | cellular response to lipoprotein particle stimulus | biological process | GO:0071402 | 26 | 6 | 17256 | 1658 |
HMGCS1,TLR4,TLR6,SYK,LDLR,ABCG1 |
| 3.352e-02 | -3.40 | regulation of synaptic vesicle exocytosis | biological process | GO:2000300 | 26 | 6 | 17256 | 1658 |
SEPT5,UNC13B,PFN2,STXBP1,LRRK2,RIMS2 |
| 3.352e-02 | -3.40 | epithelial tube branching involved in lung morphogenesis | biological process | GO:0060441 | 26 | 6 | 17256 | 1658 |
YAP1,BMP4,CELSR1,SPRY2,FOXA1,NKX2-1 |
| 3.352e-02 | -3.40 | replacement ossification | biological process | GO:0036075 | 26 | 6 | 17256 | 1658 |
RUNX2,BMP4,INPPL1,BMP6,MMP16,MEF2C |
| 3.360e-02 | -3.39 | MODULE_64 | MSigDB lists | MODULE_64 | 510 | 63 | 17377 | 1707 |
CXCR5,RGS16,DYRK3,LGALS3,IL15,PTPRD,GRB14,PRSS12,GPR65,LDLR,SELL,MAPK4,TNFRSF10C,EPHB1,IL18R1,NEO1,CD53,F3,KCNJ4,TLR3,UNC13B,HPS1,SLC16A2,GHR,EPHB6,PTPRE,JAM2,IL1RAP,PFKFB4,ITGB7,GPM6A,CD55,KCNQ3,TGFA,STAT4,LRMP,EFNA3,CR2,CALCRL,PRKCQ,ROR1,KCND3,CD40,SKAP1,LEPR,FGFR1,GPLD1,HTR7,PTPRC,CD37,CXCL10,FGR,GYPC,GPRC5B,NCKAP1L,CSF1,ATP7B,FAT1,PTPRS,OXTR,NRP1,TNFSF4,STOM |
| 3.363e-02 | -3.39 | regulation of synaptic transmission, glutamatergic | biological process | GO:0051966 | 70 | 12 | 17256 | 1658 |
CACNG3,GRIK2,KMO,SHANK2,LRRK2,OPHN1,OXTR,NRXN1,CDH2,STXBP1,DKK1,MEF2C |
| 3.367e-02 | -3.39 | GO_SARCOLEMMA | MSigDB lists | GO_SARCOLEMMA | 124 | 19 | 17377 | 1707 |
SCN5A,COL6A2,BVES,ANK2,PRKCQ,ATP1B1,KCND3,SNTB1,NOS1AP,KCNN2,SCN1B,PEMT,CACNB2,AHNAK2,ADCY6,SCN2A,CACNA2D1,ATP2B4,ATP1A3 |
| 3.370e-02 | -3.39 | skin-ear-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-ear-carcinoma-squamous_cell_carcinoma | 513 | 63 | 17385 | 1698 |
PCDH18,INPPL1,ZHX3,CELSR3,ARHGEF11,ZNF311,MSR1,BEGAIN,CHUK,IGF2BP2,SLC12A6,USP30,DENND3,COL14A1,FSTL5,SLC9A7,COL22A1,EPB41L3,RPS6KA2,FRY,UNC13B,KMO,PIK3AP1,STC2,PRKG1,PRICKLE2,MARCH3,JAKMIP2,MET,IQGAP3,TLR4,KCNB2,RBMS2,PDGFRB,DPP10,SYNPO2,SPOCD1,TDRD3,AGPAT4,KLHL4,ANK2,LITAF,ROR1,SDK1,MFSD6,PALLD,FGFR1,FAT4,TERT,ITGA2,LRRIQ3,LAMB1,INHBE,PTPRS,DLG2,ZBTB20,CYP2U1,PLD1,PPARGC1A,SUSD4,MAGI2,LIFR,AMPD1 |
| 3.381e-02 | -3.39 | VANHARANTA_UTERINE_FIBROID_DN | MSigDB lists | VANHARANTA_UTERINE_FIBROID_DN | 61 | 11 | 17377 | 1707 |
ABLIM1,MSX1,GATA2,WFS1,BCL6,ATF3,C1R,KLF5,RARRES2,MOXD1,LEPR |
| 3.381e-02 | -3.39 | GO_REGULATION_OF_MUSCLE_ADAPTATION | MSigDB lists | GO_REGULATION_OF_MUSCLE_ADAPTATION | 61 | 11 | 17377 | 1707 |
SCN5A,FBXO32,LMCD1,GTF2IRD1,ERRFI1,PRKCA,PPARGC1A,TRPC3,NEDD4,ATP2B4,NOS3 |
| 3.397e-02 | -3.38 | Oxytocin signaling pathway | KEGG pathways | ko04921 | 152 | 23 | 7161 | 730 |
PLA2G4A,PRKAA2,CACNG3,MYLK3,ADCY1,RYR2,ITPR2,GUCY1A2,PRKCA,CACNB4,PLCB1,GNAI1,KCNJ4,EEF2,PRKCB,CACNB2,GNAO1,ADCY6,OXTR,PRKACB,CACNA2D1,NOS3,MEF2C |
| 3.397e-02 | -3.38 | Oxytocin signaling pathway | KEGG pathways | hsa04921 | 152 | 23 | 7161 | 730 |
PLA2G4A,PRKAA2,CACNG3,MYLK3,ADCY1,RYR2,ITPR2,GUCY1A2,PRKCA,CACNB4,PLCB1,GNAI1,KCNJ4,EEF2,PRKCB,CACNB2,GNAO1,ADCY6,OXTR,PRKACB,CACNA2D1,NOS3,MEF2C |
| 3.398e-02 | -3.38 | skin-ankle-malignant_melanoma | COSMIC cancer mutations | skin-ankle-malignant_melanoma | 69 | 12 | 17385 | 1698 |
PTPRC,PTPRJ,PTPRD,DCC,ADAMTS3,PTPN13,PTPN21,PTPRS,PTPRN2,TNS1,PTPRE,CHRM3 |
| 3.398e-02 | -3.38 | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | MSigDB lists | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | 208 | 29 | 17377 | 1707 |
FGFR4,PAK1,SSH3,ITGB7,GNG12,VAV3,PXN,MYLK3,FN1,FGF13,DOCK1,ITGA6,FGF12,ENAH,FGF17,PFN2,RAC3,FGFR1,BAIAP2,TIAM2,SCIN,GSN,NCKAP1L,ITGA2,ITGB3,IQGAP3,RRAS2,PDGFRB,CHRM3 |
| 3.400e-02 | -3.38 | positive chemotaxis | biological process | GO:0050918 | 40 | 8 | 17256 | 1658 |
VEGFC,PTPRJ,LGALS3,HGF,BMP4,MET,NRP1,COLEC10 |
| 3.400e-02 | -3.38 | regulation of protein deacetylation | biological process | GO:0090311 | 40 | 8 | 17256 | 1658 |
BEX4,PRKAA2,FRY,JDP2,LRRK2,SREBF1,BCL6,SKI |
| 3.400e-02 | -3.38 | regulation of cell adhesion mediated by integrin | biological process | GO:0033628 | 40 | 8 | 17256 | 1658 |
NCKAP1L,ACER2,PTPN6,TESC,SYK,RAC3,SNAI2,CYP1B1 |
| 3.400e-02 | -3.38 | GSE34515_CD16_NEG_VS_POS_MONOCYTE_DN | MSigDB lists | GSE34515_CD16_NEG_VS_POS_MONOCYTE_DN | 174 | 25 | 17377 | 1707 |
ITGB7,BCL7A,ANTXR2,ALDH2,RUNX2,MVD,ARL2,SELL,TCEAL3,PRKAR2B,SYNJ2BP,CTTNBP2NL,GAS6,PRKCA,SLC9A7,DDIT4,ATPAF2,RIMKLB,ADCK1,SLC7A5,OPN3,MAP7,SYNGR3,RBMS2,SLC43A1 |
| 3.400e-02 | -3.38 | IL21_UP.V1_UP | MSigDB lists | IL21_UP.V1_UP | 174 | 25 | 17377 | 1707 |
GPR176,USP2,UGT8,ELOVL4,SCN8A,MVD,ARHGAP22,AGAP2,ARHGAP32,KIF21B,TLR6,TBC1D19,HEG1,DYRK1B,TLR3,PAIP2B,DLX6,SLC7A5,BCL6,SLCO5A1,MYH15,SPRY4,TSHR,NKX2-8,LAMP3 |
| 3.400e-02 | -3.38 | GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN | 174 | 25 | 17377 | 1707 |
PHACTR3,LATS2,CDH26,MYCBP2,ID1,PDK1,NFIA,C4orf19,NIPSNAP3B,DDIT4,GJC1,EFEMP1,IQCH,ICA1,KCNN2,MFSD9,PLOD2,PCBP4,CCDC146,MORN2,LIMCH1,RNF148,ERRFI1,THSD1,ATP2B4 |
| 3.401e-02 | -3.38 | GO_INOSITOL_LIPID_MEDIATED_SIGNALING | MSigDB lists | GO_INOSITOL_LIPID_MEDIATED_SIGNALING | 116 | 18 | 17377 | 1707 |
FGFR4,TYRO3,BTC,GATA3,PLEKHA1,FGF17,CA8,NCS1,FGFR1,IRS2,GSN,IGF1R,XBP1,PIK3C2B,INPP5F,PLD1,PDGFRB,GAB2 |
| 3.404e-02 | -3.38 | human chr8q21.2 | chromosome location | human chr8q21.2 | 10 | 3 | 26185 | 1967 |
CA2,CA13,LRRCC1 |
| 3.404e-02 | -3.38 | human chr9p24.2 | chromosome location | human chr9p24.2 | 10 | 3 | 26185 | 1967 |
VLDLR-AS1,VLDLR,RFX3-AS1 |
| 3.404e-02 | -3.38 | lower_leg | COSMIC cancer mutations | lower_leg | 175 | 25 | 17385 | 1698 |
FER,EML5,CACNG3,PTPRD,DCC,PTPN13,PTPN21,TNS1,EPHB1,KHDRBS2,FGFR1,PTPRC,TMEM132B,IKZF3,PTPRJ,TERT,ADAMTS3,PTK7,PPFIBP1,PTPRS,PTPRN2,KIF21A,MET,PTPRE,CHRM3 |
| 3.406e-02 | -3.38 | GS | smart domains | SM00467 | 7 | 3 | 9493 | 1056 |
BMPR1A,ACVR1,ACVR1C |
| 3.409e-02 | -3.38 | Stimuli-sensing channels | REACTOME pathways | R-HSA-2672351 | 104 | 16 | 10287 | 971 |
MCOLN2,TRPM4,ANO10,SLC9C1,ASIC1,MCOLN3,SGK3,TTYH2,RYR2,SGK1,TRPC1,SGK2,ASPH,TRPC3,SLC9B1,STOM |
| 3.412e-02 | -3.38 | ATP2B2 (ATPase plasma membrane Ca2+ transporting 2) | protein interactions | 491 | 121 | 19 | 17029 | 1718 |
EFNB2,ABCC4,LGR4,ATP9A,C4A,GALNT6,BTBD9,CHSY1,PRKCA,PIBF1,ENTPD7,SQLE,STEAP3,DLG2,MYH15,FAR2,RAPGEF5,GPR161,ATP2B4 |
| 3.412e-02 | -3.38 | TUBB2A (tubulin beta 2A class IIa) | protein interactions | 7280 | 121 | 19 | 17029 | 1718 |
LATS2,DISC1,TNIK,TUBA1A,TES,ARL15,SDC3,ARL2,RABAC1,KCND3,ATOH1,EML1,SKI,PTPRS,HK1,STXBP1,TPT1,HEY1,LAMP3 |
| 3.412e-02 | -3.38 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 191 | 27 | 17377 | 1707 |
PDK1,TUBA1A,MPP1,ST6GAL1,LDLR,RAPGEF4,FASN,GABRR2,ZDHHC14,SESN1,SATB1,RPL13A,DDIT4,ISG20,GSN,RPS6KA2,RALGPS2,PRKCB,RGS10,TSC22D1,MAP7,PTPRS,ADCY6,TSPAN13,MARCKS,ST8SIA1,RCAN3 |
| 3.412e-02 | -3.38 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN | 191 | 27 | 17377 | 1707 |
EPB41L5,LATS2,SLC3A2,FLVCR2,RUSC2,GDPD1,ZNF565,PKP2,FERMT2,PDE8A,PRDM1,OVOL2,RNF44,DCBLD2,RGS17,ID3,MSC,PTPRJ,PCBP4,STARD4,TUFT1,FIGN,RNF157,ETV1,TMEM120B,RASGRP1,B4GALT7 |
| 3.412e-02 | -3.38 | WIERENGA_STAT5A_TARGETS_DN | MSigDB lists | WIERENGA_STAT5A_TARGETS_DN | 191 | 27 | 17377 | 1707 |
SUSD3,EFNB2,WASF3,ITGB7,SLC37A1,UBASH3B,PSTPIP2,C3orf52,EFHC2,DEPTOR,MSRB3,COTL1,BATF,DENND3,JAM3,CTIF,IRS2,ARHGAP21,PRTFDC1,PLXDC2,RBPMS2,NAP1L3,SH3BGRL2,PROS1,FAR2,SMAD6,TSPAN9 |
| 3.412e-02 | -3.38 | GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_UP | MSigDB lists | GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_UP | 191 | 27 | 17377 | 1707 |
GNG12,ANTXR2,RHOQ,KLHL23,TBC1D1,RECK,SYT12,SLC39A8,PRICKLE1,SLITRK5,GSTO1,MBNL2,PFN2,ISG20,CCDC120,NAV1,TMEM237,LRRN1,PPFIBP1,STARD4,MAP7,RCN3,CTTN,CLVS2,BARX1,FMNL2,RRAGD |
| 3.412e-02 | -3.38 | GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | 191 | 27 | 17377 | 1707 |
MSX1,PLSCR4,IL32,CFH,IL15,LDLR,ARID5B,C1R,SLC25A28,ATP10D,BATF3,WARS,ISG20,HEG1,CEBPB,PTPRC,CXCL10,TLR3,PMAIP1,GBP1,CSF1,BCL6,HK1,MET,CEBPD,CAND2,SNX7 |
| 3.412e-02 | -3.38 | GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP | MSigDB lists | GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP | 191 | 27 | 17377 | 1707 |
TUBA1A,ITGA6,EPS8,LITAF,SELL,RASA3,NPM1,KCTD12,RASD1,SCD,ADSSL1,EBF1,EPCAM,MCOLN2,ARHGAP21,MYADM,RALGPS2,MGAT1,MYC,PRKCD,RAB31,HK2,SQLE,SERPINI1,TSPAN13,PLTP,SYK |
| 3.412e-02 | -3.38 | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_IL1R_KO_MOUSE_LUNG_DC_DN | MSigDB lists | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_IL1R_KO_MOUSE_LUNG_DC_DN | 191 | 27 | 17377 | 1707 |
TMEM63C,INPPL1,TMEM65,ABCC2,SHISA2,NTRK3,ZNF219,TTC28,TNFRSF19,ZIC1,FBXO32,SOAT2,KMO,AKT3,MPPED2,MAP7,PTPRS,PTPRN2,CADPS2,KLF9,CERS4,OXTR,MDH1B,FIGN,VASH2,CTH,ZNF235 |
| 3.412e-02 | -3.38 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 191 | 27 | 17377 | 1707 |
PCSK1N,RHOQ,SLC37A1,CYP2J2,TGFA,ARL15,MYO1B,ATOX1,ABCC2,ATF3,SAV1,CD40,PALLD,MSC,PMAIP1,MAP2,ITGB3,RUNDC3B,HK2,SVIL,IPCEF1,VASH2,JAM2,SNX10,HSPA2,SP140L,LAMP3 |
| 3.412e-02 | -3.38 | adherens junction organization | biological process | GO:0034332 | 78 | 13 | 17256 | 1658 |
RASSF8,CDH26,NUMBL,SORBS1,RHOD,ITGA2,CDH17,FERMT2,INAVA,CADM2,CTTN,DSP,CDH2 |
| 3.413e-02 | -3.38 | LU_IL4_SIGNALING | MSigDB lists | LU_IL4_SIGNALING | 92 | 15 | 17377 | 1707 |
EBF1,VEGFC,QSOX1,ARAP2,TLR3,PMAIP1,KMO,STAT4,XBP1,BCL6,SELL,BATF,SEL1L3,TNFRSF11A,RRAGD |
| 3.417e-02 | -3.38 | PICK1 (protein interacting with PRKCA 1) | protein interactions | 9463 | 82 | 14 | 17029 | 1718 |
GPR37,EFNB2,PRKN,ICA1,GRIK2,ITGA6,ASIC1,GRIP1,UACA,ATP11A,AMIGO1,PRKCA,GFI1,JAM3 |
| 3.422e-02 | -3.37 | growth | biological process | GO:0040007 | 365 | 46 | 17256 | 1658 |
PLAG1,LRP4,GATA3,APBA1,SELENOP,DDR1,GAS1,COL27A1,FOXP2,TGFBR3,FLRT3,LRP6,PDE4D,SLIT2,SPRY2,PDGFRB,EPB41L5,BDNF,KDM5B,MSTN,SHANK2,ARID5B,YAP1,NLGN4X,WNT11,PLEKHA1,ACVR2B,LEPR,HEG1,MAP1B,SMAD3,GSN,SH3GL2,CSF1,PTK7,WWTR1,SELENOM,HOXD13,BMPR1A,BMP4,NRP1,DHCR7,SEMA3A,MAGI2,APBA2,COBL |
| 3.423e-02 | -3.37 | GO_RESPONSE_TO_AMINO_ACID | MSigDB lists | GO_RESPONSE_TO_AMINO_ACID | 108 | 17 | 17377 | 1707 |
CEBPB,GSN,ASNS,ZNF354A,EEF2,BCHE,PEMT,XBP1,IPO5,SH3BP4,ASS1,CHUK,PPARGC1A,AARS,CPEB1,MGMT,RRAGD |
| 3.423e-02 | -3.37 | GO_FORMATION_OF_PRIMARY_GERM_LAYER | MSigDB lists | GO_FORMATION_OF_PRIMARY_GERM_LAYER | 108 | 17 | 17377 | 1707 |
EPB41L5,ACVR1,FN1,BMPR2,WLS,WNT11,DKK1,MMP15,SMAD3,EOMES,LAMB1,ITGB3,ITGA2,BMPR1A,BMP4,SIX2,DUSP1 |
| 3.423e-02 | -3.37 | FIGUEROA_AML_METHYLATION_CLUSTER_1_UP | MSigDB lists | FIGUEROA_AML_METHYLATION_CLUSTER_1_UP | 108 | 17 | 17377 | 1707 |
DNM3,PRRG1,MSRB3,TBC1D16,PFN2,ARHGAP44,CENPV,TXNRD3,SYDE2,SLC39A14,ABLIM1,PMAIP1,GAN,MAP7,JAKMIP2,DHRS12,VWA5A |
| 3.426e-02 | -3.37 | positive regulation of protein binding | biological process | GO:0032092 | 86 | 14 | 17256 | 1658 |
EPB41L5,TRIB3,PRKN,BDNF,TERT,DACT1,PLK2,RAPGEF2,LRRK2,ADD2,BMP4,NRP1,HERPUD1,MEF2C |
| 3.426e-02 | -3.37 | positive regulation of lymphocyte differentiation | biological process | GO:0045621 | 86 | 14 | 17256 | 1658 |
PNP,IL15,NCKAP1L,XBP1,BCL6,GATA3,TOX,STAT5B,PRDM1,GAS6,TNFSF4,TESPA1,SYK,RASGRP1 |
| 3.426e-02 | -3.37 | regulation of axon extension | biological process | GO:0030516 | 86 | 14 | 17256 | 1658 |
NKX6-1,PAK1,FN1,SEMA4F,BMPR2,PLXNA2,PTPRS,SEMA3C,NTRK3,CTTN,NRP1,SEMA3A,SHTN1,MAP1B |
| 3.427e-02 | -3.37 | SH2 | smart domains | SM00252 | 103 | 18 | 9493 | 1056 |
FER,VAV3,SH3BP2,INPPL1,SH2D2A,GRB14,PTPN6,STAT5B,TNS1,LCP2,FRK,CHN1,CHN2,FGR,SHF,GRB10,SYK,FES |
| 3.428e-02 | -3.37 | GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 593 | 72 | 17377 | 1707 |
NEK10,AVPI1,ACSL1,FGF13,NTRK3,LCP2,SNX9,PIBF1,PPP1R9A,TLR3,CDC14B,ITGB3,SERINC2,DAB2IP,MARCKS,TLR4,HSPA2,RASGRP1,PRKACB,PDGFRB,PFKFB2,FZD4,TGFA,LRRK2,ADCY1,PRKAR2B,PRKCQ,WNT11,ACVR2B,CD40,FGFR1,SNCA,NRG3,GPRC5B,NCKAP1L,ERN1,DUSP19,TNFSF15,HGF,DIRAS1,MAPK10,TNIK,SERINC5,FZD8,GAS6,PKN1,TPD52L1,GHR,PRKCD,ADCY6,AFAP1L2,IQGAP3,TNFRSF11A,SYK,SPRY2,PAK1,VAV3,RAPGEF2,VLDLR,DUSP9,STRADB,ARRDC4,TLR6,PTPRC,MAPKAPK2,TRIB3,FGR,CSF1,MAP2K6,BMP4,BTRC,ATP2B4 |
| 3.428e-02 | -3.37 | negative regulation of glial cell apoptotic process | biological process | GO:0034351 | 8 | 3 | 17256 | 1658 |
GAS6,PRKCA,PRKCD |
| 3.428e-02 | -3.37 | copper ion import | biological process | GO:0015677 | 8 | 3 | 17256 | 1658 |
STEAP3,STEAP1,ATP7B |
| 3.428e-02 | -3.37 | endothelial cell apoptotic process | biological process | GO:0072577 | 8 | 3 | 17256 | 1658 |
DAB2IP,BMPR2,COL4A3 |
| 3.428e-02 | -3.37 | galactosylceramide metabolic process | biological process | GO:0006681 | 8 | 3 | 17256 | 1658 |
UGT8,B3GALT1,B3GALT2 |
| 3.428e-02 | -3.37 | cellular response to caffeine | biological process | GO:0071313 | 8 | 3 | 17256 | 1658 |
RYR2,GSTM2,PPARGC1A |
| 3.428e-02 | -3.37 | skeletal muscle atrophy | biological process | GO:0014732 | 8 | 3 | 17256 | 1658 |
PPARGC1A,IL15,MSTN |
| 3.428e-02 | -3.37 | positive regulation of phospholipid transport | biological process | GO:2001140 | 8 | 3 | 17256 | 1658 |
ATP8A1,PRKCD,PRELID1 |
| 3.428e-02 | -3.37 | negative regulation of cardiac muscle adaptation | biological process | GO:0010616 | 8 | 3 | 17256 | 1658 |
SMAD3,ERRFI1,ATP2B4 |
| 3.428e-02 | -3.37 | axon extension involved in axon guidance | biological process | GO:0048846 | 8 | 3 | 17256 | 1658 |
NRP1,SEMA3A,SLIT2 |
| 3.428e-02 | -3.37 | regulation of guanyl-nucleotide exchange factor activity | biological process | GO:1905097 | 8 | 3 | 17256 | 1658 |
RIPOR2,MET,GPSM1 |
| 3.428e-02 | -3.37 | negative regulation of cardiac muscle hypertrophy in response to stress | biological process | GO:1903243 | 8 | 3 | 17256 | 1658 |
SMAD3,ERRFI1,ATP2B4 |
| 3.428e-02 | -3.37 | intracellular distribution of mitochondria | biological process | GO:0048312 | 8 | 3 | 17256 | 1658 |
SYNJ2BP,BHLHA15,LRRK2 |
| 3.428e-02 | -3.37 | ventricular compact myocardium morphogenesis | biological process | GO:0003223 | 8 | 3 | 17256 | 1658 |
BMPR1A,TGFBR3,DSP |
| 3.428e-02 | -3.37 | lung-associated mesenchyme development | biological process | GO:0060484 | 8 | 3 | 17256 | 1658 |
WNT11,PTK7,FGFR1 |
| 3.428e-02 | -3.37 | glomerulus morphogenesis | biological process | GO:0072102 | 8 | 3 | 17256 | 1658 |
BMP4,PDGFRB,MEF2C |
| 3.428e-02 | -3.37 | regulation of phospholipid transport | biological process | GO:2001138 | 8 | 3 | 17256 | 1658 |
ATP8A1,PRKCD,PRELID1 |
| 3.428e-02 | -3.37 | neuron projection extension involved in neuron projection guidance | biological process | GO:1902284 | 8 | 3 | 17256 | 1658 |
NRP1,SEMA3A,SLIT2 |
| 3.428e-02 | -3.37 | luteinization | biological process | GO:0001553 | 8 | 3 | 17256 | 1658 |
STAT5B,PLEKHA1,FZD4 |
| 3.428e-02 | -3.37 | actin filament severing | biological process | GO:0051014 | 8 | 3 | 17256 | 1658 |
GSN,DSTN,SCIN |
| 3.428e-02 | -3.37 | GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 100 | 16 | 17377 | 1707 |
SMAD3,NBL1,ACVR1,TGFBR3,PMEPA1,FBN1,CHRDL1,RASL11B,SYNJ2BP,SMAD6,MAGI2,MECOM,SKI,FZD1,DKK1,NKX2-1 |
| 3.428e-02 | -3.37 | GTTGNYNNRGNAAC_UNKNOWN | MSigDB lists | GTTGNYNNRGNAAC_UNKNOWN | 100 | 16 | 17377 | 1707 |
TRDMT1,B9D1,RHOBTB1,AGPAT4,STAT5B,NUP62CL,CHD5,TSKU,TUBB4A,LRRIQ3,ANKFN1,MPP2,FANK1,MAPK10,MORN4,C3orf67 |
| 3.428e-02 | -3.37 | human chr6q24.2 | chromosome location | human chr6q24.2 | 17 | 4 | 26185 | 1967 |
PHACTR2,AIG1,PLAGL1,ADGRG6 |
| 3.435e-02 | -3.37 | DM10 | smart domains | SM00676 | 3 | 2 | 9493 | 1056 |
EFHC1,EFHC2 |
| 3.435e-02 | -3.37 | Sorb | smart domains | SM00459 | 3 | 2 | 9493 | 1056 |
SORBS3,SORBS1 |
| 3.435e-02 | -3.37 | TECPR | smart domains | SM00706 | 3 | 2 | 9493 | 1056 |
TECPR1,TECPR2 |
| 3.435e-02 | -3.37 | Longevity regulating pathway | KEGG pathways | hsa04211 | 89 | 15 | 7161 | 730 |
CREB3L2,PRKAA2,IRS2,SESN2,ATF4,IGF1R,AKT3,EIF4EBP1,ADCY1,ADCY6,CREB5,ATG5,PPARGC1A,SESN1,PRKACB |
| 3.441e-02 | -3.37 | UTRN (utrophin) | protein interactions | 7402 | 67 | 12 | 17029 | 1718 |
LATS2,DISC1,THOC5,TES,NPM1,TNS1,ATOH1,SAV1,SNTB1,TTC30B,THOC3,MME |
| 3.444e-02 | -3.37 | bicellular tight junction assembly | biological process | GO:0070830 | 33 | 7 | 17256 | 1658 |
ARL2,POF1B,WNT11,MPP7,MARVELD2,OCLN,PATJ |
| 3.444e-02 | -3.37 | regulation of hydrogen peroxide-induced cell death | biological process | GO:1903205 | 33 | 7 | 17256 | 1658 |
GPR37,PDE8A,HGF,RACK1,MET,LRRK2,PYCR1 |
| 3.444e-02 | -3.37 | olfactory lobe development | biological process | GO:0021988 | 33 | 7 | 17256 | 1658 |
DLX2,EOMES,ROBO2,SEMA3A,SLIT2,LRRK2,SKI |
| 3.451e-02 | -3.37 | developmental growth | biological process | GO:0048589 | 347 | 44 | 17256 | 1658 |
PLAG1,LRP4,GATA3,APBA1,DDR1,GAS1,COL27A1,TGFBR3,FLRT3,LRP6,PDE4D,SPRY2,SLIT2,PDGFRB,EPB41L5,BDNF,KDM5B,MSTN,ARID5B,SHANK2,NLGN4X,YAP1,WNT11,ACVR2B,PLEKHA1,LEPR,MAP1B,HEG1,SMAD3,GSN,SH3GL2,PTK7,CSF1,WWTR1,SELENOM,HOXD13,BMP4,BMPR1A,NRP1,APBA2,MAGI2,SEMA3A,DHCR7,COBL |
| 3.455e-02 | -3.37 | protein binding, bridging | molecular function | GO:0030674 | 167 | 24 | 17224 | 1680 |
VAV3,SH3BP2,SORBS1,SKAP2,SH2D2A,GRB14,ANK2,EPS8,HIP1,JCHAIN,ARRDC4,SKAP1,DSP,COL14A1,BAIAP2,CHN1,CHN2,ERG28,MAP1A,FLRT3,SHF,COL19A1,GRB10,GAB2 |
| 3.458e-02 | -3.36 | AGPAT3 (1-acylglycerol-3-phosphate O-acyltransferase 3) | protein interactions | 56894 | 25 | 6 | 17029 | 1718 |
SLC7A1,SLC6A15,GPM6A,TMEM120B,TSPAN17,ARL15 |
| 3.458e-02 | -3.36 | PLCB1 (phospholipase C beta 1) | protein interactions | 23236 | 25 | 6 | 17029 | 1718 |
CTBP2,PRKCA,PLCB1,TRPC3,PRKCD,GAN |
| 3.458e-02 | -3.36 | ZFP64 (ZFP64 zinc finger protein) | protein interactions | 55734 | 25 | 6 | 17029 | 1718 |
HECW2,MAFB,ERG28,FAM124A,BEGAIN,FHL2 |
| 3.458e-02 | -3.36 | KLK7 (kallikrein related peptidase 7) | protein interactions | 5650 | 25 | 6 | 17029 | 1718 |
VNN2,PTPRJ,CA8,PLK2,ZIC1,UBAC2 |
| 3.458e-02 | -3.36 | ELMO1 (engulfment and cell motility 1) | protein interactions | 9844 | 25 | 6 | 17029 | 1718 |
BAG3,ADGRB3,DOCK3,DOCK5,DOCK1,DOCK2 |
| 3.458e-02 | -3.36 | TTC26 (tetratricopeptide repeat domain 26) | protein interactions | 79989 | 25 | 6 | 17029 | 1718 |
TTC30A,IFT81,LCA5,TTC30B,PTPN21,GLI1 |
| 3.465e-02 | -3.36 | MET activates PTK2 signaling | REACTOME pathways | R-HSA-8874081 | 20 | 5 | 10287 | 971 |
LAMC3,HGF,MET,LAMB1,ITGA2 |
| 3.465e-02 | -3.36 | Syndecan interactions | REACTOME pathways | R-HSA-3000170 | 20 | 5 | 10287 | 971 |
SDC3,PRKCA,ITGA6,ITGB3,ITGA2 |
| 3.466e-02 | -3.36 | foot | COSMIC cancer mutations | foot | 150 | 22 | 17385 | 1698 |
PAGE1,PTPRD,DCC,PTPN13,PTPN21,TNS1,KHDRBS2,PTPRC,TMEM132B,PTPRJ,FAT4,FRY,ADAMTS3,PPFIBP1,STC2,PTPRS,PTPRN2,PRICKLE2,COG3,MET,PTPRE,CHRM3 |
| 3.474e-02 | -3.36 | regulation of hormone levels | biological process | GO:0010817 | 513 | 62 | 17256 | 1658 |
PRKN,PCSK1N,C1QTNF3,STXBP5L,VAMP8,ARL2,GATA3,STAT5B,ITPR2,P2RY1,ABAT,NRXN1,PRKCA,PCLO,BMP6,CYP26A1,MCU,NKX6-1,RAB11FIP5,BACE2,ERO1B,SLC16A2,GHR,STC2,SREBF1,KCNS3,MARCKS,PCK2,MYRIP,GFI1,CPE,RIMS2,PCSK6,HMGCR,CYP1B1,TRPM4,KDM5B,ACVR1C,FZD4,PFKFB2,CACNA1E,SYBU,RAPGEF4,ABCC2,SNAP25,ACVR2B,PLEKHA1,LRAT,ILDR2,FGFR1,GPLD1,IRS2,ICA1,SRD5A3,SELENOM,PTPRN2,PPARGC1A,DHCR7,SLC16A10,MME,FOXA1,PCSK5 |
| 3.475e-02 | -3.36 | regulation of actin filament polymerization | biological process | GO:0030833 | 161 | 23 | 17256 | 1658 |
TENM1,FER,EVL,TMSB15A,EPS8,PREX1,ADD2,PFN2,RAC3,PPP1R9A,BAIAP2,SPIRE1,FHOD3,SCIN,GSN,MYADM,NCKAP1L,WIPF3,PRKCD,ARHGAP28,TMOD2,CTTN,SLIT2 |
| 3.476e-02 | -3.36 | MARKEY_RB1_ACUTE_LOF_DN | MSigDB lists | MARKEY_RB1_ACUTE_LOF_DN | 217 | 30 | 17377 | 1707 |
MXI1,GCNT2,PDK1,PNP,SKAP2,PTPN6,LDLR,CYP4V2,BNIP3L,AK4,NDRG2,FNDC3A,FAM162A,ISG20,PTPRC,MCOLN2,CXCL10,NCKAP1L,GBP1,ALDOC,CPXM2,SH3BGRL2,CMPK2,GATM,DDIT3,SMPDL3A,ABCG1,IGFBP3,PCSK5,STOM |
| 3.479e-02 | -3.36 | regulation of calcium ion transmembrane transport | biological process | GO:1903169 | 144 | 21 | 17256 | 1658 |
GSTM2,PTPN6,ANK2,UBASH3B,JPH1,RYR2,GSTO1,ATP1B1,CACNB4,NOS1AP,SNCA,CXCL10,CACNB2,EHD3,TRPC1,TSPAN13,PDE4D,GEM,ATG5,HSPA2,CACNA2D1 |
| 3.489e-02 | -3.36 | GO_REGULATION_OF_CELL_SIZE | MSigDB lists | GO_REGULATION_OF_CELL_SIZE | 166 | 24 | 17377 | 1707 |
BDNF,VAV3,DISC1,SEMA6B,FN1,BMPR2,FGF13,DCC,DEPTOR,PLXNA2,NTRK3,SEMA6A,MAP1B,BCL11A,NKX6-1,RND2,SEMA4F,SEMA3C,CTTN,IQGAP3,NRP1,SEMA3A,PRR16,SEMA6C |
| 3.489e-02 | -3.36 | GSE4748_CYANOBACTERIUM_LPSLIKE_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | MSigDB lists | GSE4748_CYANOBACTERIUM_LPSLIKE_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP | 166 | 24 | 17377 | 1707 |
CXCR5,SIDT1,SH2D2A,ARID5B,ATF7IP2,PLEKHA1,SNX9,AARS,BCL11A,EBF1,SPATA9,BACH2,RPL28,PMEPA1,XBP1,TSPAN13,RTKN2,PIK3C2B,HS3ST3B1,ST8SIA1,TNFRSF17,FANK1,SCN3A,MEF2C |
| 3.494e-02 | -3.35 | secondary metabolic process | biological process | GO:0019748 | 55 | 10 | 17256 | 1658 |
GSTO2,KMO,BDH2,PAM,CBS,TRPC1,ABCC2,GSTO1,CYP1B1,CTH |
| 3.494e-02 | -3.35 | alpha-beta T cell activation | biological process | GO:0046631 | 55 | 10 | 17256 | 1658 |
BCL11B,EOMES,IL15,GATA3,TNFSF4,BATF,SATB1,DOCK2,IL18R1,SYK |
| 3.495e-02 | -3.35 | - | gene3d domains | 1.20.120.350 | 71 | 13 | 8148 | 867 |
KCNV1,SCN5A,SLC9C1,CACNA1E,SCN8A,KCNH5,KCNG1,KCNS3,KCND3,SCN2A,KCNC4,SCN3A,KCNB2 |
| 3.499e-02 | -3.35 | GO_EXOCYTIC_VESICLE | MSigDB lists | GO_EXOCYTIC_VESICLE | 141 | 21 | 17377 | 1707 |
DOC2A,DMXL2,SV2B,SLC40A1,DISC1,RAB3B,SCAMP1,SYT12,LRRK2,RABAC1,APBA1,SNCA,TRIM9,ICA1,PTPRN2,SYNGR3,SEPT5,APBA2,CTTNBP2,STON2,MME |
| 3.500e-02 | -3.35 | RGS | smart domains | SM00315 | 35 | 8 | 9493 | 1056 |
RGS17,RGS16,GRK6,RGS7,ARHGEF11,GRK3,RGS10,RGS20 |
| 3.508e-02 | -3.35 | PLAC | prosite domains | PS50900 | 18 | 5 | 12060 | 1278 |
ADAMTS17,ADAMTS6,ADAMTS3,THSD4,PCSK6 |
| 3.509e-02 | -3.35 | FGF7 (fibroblast growth factor 7) | protein interactions | 2252 | 13 | 4 | 17029 | 1718 |
DESI1,FGFR4,NRP1,FGFR1 |
| 3.509e-02 | -3.35 | RCAN3 (RCAN family member 3) | protein interactions | 11123 | 13 | 4 | 17029 | 1718 |
PLS1,GRB10,SMYD3,EPS8 |
| 3.509e-02 | -3.35 | IGSF1 (immunoglobulin superfamily member 1) | protein interactions | 3547 | 13 | 4 | 17029 | 1718 |
ACVR2A,ACVR2B,BMPR1A,ACVR1 |
| 3.509e-02 | -3.35 | COL10A1 (collagen type X alpha 1 chain) | protein interactions | 1300 | 13 | 4 | 17029 | 1718 |
COLGALT2,MPP1,BTRC,C1QL4 |
| 3.509e-02 | -3.35 | ALDH1L2 (aldehyde dehydrogenase 1 family member L2) | protein interactions | 160428 | 13 | 4 | 17029 | 1718 |
SUGT1,MYCBP2,TUBA1A,ALDH1L1 |
| 3.509e-02 | -3.35 | PLEKHG4 (pleckstrin homology and RhoGEF domain containing G4) | protein interactions | 25894 | 13 | 4 | 17029 | 1718 |
EFNB2,DOCK5,TNFRSF19,FOXG1 |
| 3.509e-02 | -3.35 | Tpm4 (tropomyosin 4) | protein interactions | 326618 | 13 | 4 | 17029 | 1718 |
SVIL,GSN,TPM1,HACE1 |
| 3.509e-02 | -3.35 | GLT8D2 (glycosyltransferase 8 domain containing 2) | protein interactions | 83468 | 13 | 4 | 17029 | 1718 |
QSOX1,BNIP1,MME,CACNA2D1 |
| 3.509e-02 | -3.35 | CKMT2 (creatine kinase, mitochondrial 2) | protein interactions | 1160 | 13 | 4 | 17029 | 1718 |
TMED9,ABHD6,ALDOC,ALDOA |
| 3.509e-02 | -3.35 | KANK1 (KN motif and ankyrin repeat domains 1) | protein interactions | 23189 | 13 | 4 | 17029 | 1718 |
EPB41L3,KIF21A,ENO1,BAIAP2 |
| 3.509e-02 | -3.35 | ZBP1 (Z-DNA binding protein 1) | protein interactions | 81030 | 13 | 4 | 17029 | 1718 |
CTBP2,ZNF516,PLXDC2,PALD1 |
| 3.509e-02 | -3.35 | RAPGEF4 (Rap guanine nucleotide exchange factor 4) | protein interactions | 11069 | 13 | 4 | 17029 | 1718 |
MAP1A,RRAS2,RIMS2,RAP2A |
| 3.509e-02 | -3.35 | FAM187B (family with sequence similarity 187 member B) | protein interactions | 148109 | 13 | 4 | 17029 | 1718 |
TUBA1A,CANX,CLGN,ATP1A3 |
| 3.511e-02 | -3.35 | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | 183 | 26 | 17377 | 1707 |
SUSD3,EVL,SLC39A8,GALNT12,MLF1,MORC4,GATA3,PHACTR2,STAT5B,NPDC1,ATXN7L1,BAG3,GTSF1,RASGRF2,FAAH2,TMEM143,TRPC1,SFMBT1,FAM84B,ST8SIA1,DBP,MAST4,RNF157,MLLT3,RASGRP1,DOCK9 |
| 3.511e-02 | -3.35 | GSE17721_POLYIC_VS_CPG_8H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_8H_BMDC_UP | 183 | 26 | 17377 | 1707 |
ITGB7,PRSS16,CFH,UGDH,NFIA,TMTC4,AIG1,SLC25A28,LPIN3,TPK1,PCDH7,ENTPD1,TMCO3,CHRNA5,PRCP,PLK2,EEPD1,BCL6,SH3BP4,SGK1,PROS1,NIPAL2,VGLL4,RBMS2,DOCK8,ABCG1 |
| 3.511e-02 | -3.35 | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | 183 | 26 | 17377 | 1707 |
MN1,DZANK1,LONRF1,DYRK3,SKAP2,MYO10,LRP4,ARID5B,MCTP2,SHISA2,WDFY4,ABAT,FRK,SATB1,GABARAPL1,SMAD3,EBF1,ERN1,ALDH1L1,TNFRSF1A,MPPED2,SH3PXD2B,GEM,ETV1,SLIT2,PDGFRB |
| 3.511e-02 | -3.35 | GSE4748_CTRL_VS_LPS_STIM_DC_3H_DN | MSigDB lists | GSE4748_CTRL_VS_LPS_STIM_DC_3H_DN | 183 | 26 | 17377 | 1707 |
NBL1,RAB3B,GCNT2,RNF144A,NR4A1,STAT4,SPATA6,MGAT4B,CBS,COL18A1,ATF3,CCNG1,RARRES2,BATF,ARRDC4,IKZF2,MSMO1,TNFRSF1A,LMAN2,CERS4,LRRK1,RBMS2,TMEM56,CTH,ABCG1,DUSP1 |
| 3.511e-02 | -3.35 | GSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN | MSigDB lists | GSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN | 183 | 26 | 17377 | 1707 |
ANO10,MICAL2,TUBA1A,RASAL2,SFXN4,TNFSF13B,LITAF,TTYH2,ATP1B1,CD40,PLCB1,CDS1,ZNF711,MSC,SLC7A11,PMAIP1,PEMT,SRD5A3,SLC2A6,CCNA1,SVIL,TBC1D9,PTPRE,RNF122,RASGRP1,CYP1B1 |
| 3.511e-02 | -3.35 | TGASTMAGC_V$NFE2_01 | MSigDB lists | TGASTMAGC_V$NFE2_01 | 183 | 26 | 17377 | 1707 |
NUDT10,PLBD2,GAPDH,SEC24D,MYO10,ASS1,ARHGAP32,PRDM1,ABHD4,PRR7,PHLDA2,GABARAPL1,PLS3,TUBB4A,TTC1,TECPR1,ABI3BP,SLC22A18,AKT3,ALDOA,SH3BGRL2,DIRAS1,BNIP3,PDE4D,ENO1,SNX10 |
| 3.511e-02 | -3.35 | GSE29618_MONOCYTE_VS_PDC_DN | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DN | 183 | 26 | 17377 | 1707 |
BCL7A,RUNX2,ALOX5AP,SIDT1,ATP8A1,SETBP1,COBLL1,GAS6,RGS7,EPHB1,SEL1L3,ASPH,IL18R1,HERPUD1,SLC9A7,BCL11A,MAPKAPK2,RPS6KA2,MAP1A,SLC7A11,MAP2K6,SLC7A5,AHNAK2,PTPRS,TSPAN13,NRP1 |
| 3.511e-02 | -3.35 | GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP | MSigDB lists | GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP | 183 | 26 | 17377 | 1707 |
HBG2,SKAP2,CLYBL,TDRD3,GPR65,ELOVL7,BNIP3L,SDC3,AK4,BCL6B,GPR180,MFSD6,SGK2,SATB1,FKBP11,IL17D,SLC30A4,TDO2,RBPMS2,REEP1,LAPTM4B,KLF9,ERRFI1,SMAD6,ZNF518B,LPP |
| 3.511e-02 | -3.35 | GSE24210_IL35_TREATED_VS_RESTING_TREG_DN | MSigDB lists | GSE24210_IL35_TREATED_VS_RESTING_TREG_DN | 183 | 26 | 17377 | 1707 |
BTC,DUSP8,SH2D2A,BVES,KLHL23,STXBP6,PLAG1,ZNF25,TRAM1L1,TMTC4,ADD2,SORBS3,ARHGAP44,TSKU,DYRK1B,GATA2,GTSF1,KAZN,MARVELD2,CCDC169,MPP2,MAP7,PPP2R2B,MYRIP,MAPK10,TSPAN9 |
| 3.511e-02 | -3.35 | GSE40443_INDUCED_VS_TOTAL_TREG_DN | MSigDB lists | GSE40443_INDUCED_VS_TOTAL_TREG_DN | 183 | 26 | 17377 | 1707 |
ITGB7,LATS2,EML6,SIDT1,MYO10,TNFAIP8L2,GABRR2,SFXN3,CD7,KBTBD11,FAM174B,GPR19,FAM131B,SKI,ENPP1,GPRIN1,SEMA4F,MYC,PELI2,PRELID2,SGK1,FAM84B,CMPK2,PSPH,SMPDL3A,CACNA2D1 |
| 3.511e-02 | -3.35 | GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_DN | 183 | 26 | 17377 | 1707 |
B9D1,GXYLT2,LRFN5,SORBS1,ELOVL7,LDLR,WDR25,C20orf194,SATB2,ABCC2,LHPP,PRKCA,ASPH,TXNRD3,AHRR,RAB11FIP5,FCHO2,ERN1,ITGB3,RGS10,LMAN2,GULP1,PROS1,MYO6,PRR16,CHMP4C |
| 3.511e-02 | -3.35 | GO_CILIUM_MORPHOGENESIS | MSigDB lists | GO_CILIUM_MORPHOGENESIS | 183 | 26 | 17377 | 1707 |
B9D1,INTU,DISC1,TMEM67,ABCC4,TCTN2,CELSR3,SPATA6,TTC30A,BBS9,PIBF1,TTC30B,ARMC4,IFT81,ABLIM1,GSN,TMEM237,LRRC6,EHD3,WWTR1,WDR19,DYNC2LI1,DYNC2H1,FNBP1L,DNAH5,SNX10 |
| 3.516e-02 | -3.35 | skin-upper_back-malignant_melanoma | COSMIC cancer mutations | skin-upper_back-malignant_melanoma | 324 | 42 | 17385 | 1698 |
DMXL2,PTPRD,CKAP2,CELSR3,ATP8A1,PTPN21,HECW2,CADM2,EPHB1,RGS7,FHOD3,SIPA1L2,UNC13B,FUT9,DSG2,MET,PTPRE,DNAH5,AGL,CHRM3,PTCH2,FER,ERGIC1,KCNQ3,SLC36A1,PTPRU,DCC,PTPN13,PARD3B,LRMP,TNS1,PRDM1,KHDRBS2,PTPRC,TMEM132B,PTPRJ,FAT4,PTK7,EMILIN2,PTPRS,PTPRN2,CNTN1 |
| 3.519e-02 | -3.35 | myelofibrosis | COSMIC cancer mutations | myelofibrosis | 423 | 53 | 17385 | 1698 |
FRMPD3,TFCP2L1,SCN5A,THOC5,RUNX2,PRSS12,ST6GAL1,LRP4,UBAC2,PLXNA2,SETBP1,NPM1,STAT5B,CEBPA,CADM2,KIAA1217,BBS9,NEDD4,MTUS1,COL22A1,KIAA1958,GATA2,FUT9,ITGB3,ZNF521,GULP1,VWA5A,RIMS2,PRKACB,GAB2,CYP1B1,TBC1D8B,CACNA1E,MCF2L2,GRID1,SPATA13,ADCY1,OBSCN,C4BPB,PTPRC,FAT4,CSAG1,RASGRF2,FAM114A2,TMPRSS9,CECR2,ALG11,UNC5B,KIF1B,NPHP1,DCBLD1,LARP1,DOCK9 |
| 3.519e-02 | -3.35 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelofibrosis | 423 | 53 | 17385 | 1698 |
FRMPD3,TFCP2L1,SCN5A,THOC5,RUNX2,PRSS12,ST6GAL1,LRP4,UBAC2,PLXNA2,SETBP1,NPM1,STAT5B,CEBPA,CADM2,KIAA1217,BBS9,NEDD4,MTUS1,COL22A1,KIAA1958,GATA2,FUT9,ITGB3,ZNF521,GULP1,VWA5A,RIMS2,PRKACB,GAB2,CYP1B1,TBC1D8B,CACNA1E,MCF2L2,GRID1,SPATA13,ADCY1,OBSCN,C4BPB,PTPRC,FAT4,CSAG1,RASGRF2,FAM114A2,TMPRSS9,CECR2,ALG11,UNC5B,KIF1B,NPHP1,DCBLD1,LARP1,DOCK9 |
| 3.524e-02 | -3.35 | human chr10q22.1 | chromosome location | human chr10q22.1 | 51 | 8 | 26185 | 1967 |
TSPAN15,PALD1,P4HA1,HK1,VSIR,UNC5B,DDIT4,MCU |
| 3.527e-02 | -3.34 | Inflammatory mediator regulation of TRP channels | KEGG pathways | ko04750 | 97 | 16 | 7161 | 730 |
PLA2G4A,CYP2J2,ADCY1,PRKCQ,ITPR2,PRKCA,PLCB1,PRKCB,MAP2K6,PRKCD,ASIC1,ADCY6,MAPK13,MAPK10,IL1RAP,PRKACB |
| 3.527e-02 | -3.34 | Inflammatory mediator regulation of TRP channels | KEGG pathways | hsa04750 | 97 | 16 | 7161 | 730 |
PLA2G4A,CYP2J2,ADCY1,PRKCQ,ITPR2,PRKCA,PLCB1,PRKCB,MAP2K6,PRKCD,ASIC1,ADCY6,MAPK13,MAPK10,IL1RAP,PRKACB |
| 3.528e-02 | -3.34 | extracellular exosome | cellular component | GO:0070062 | 2118 | 224 | 18223 | 1724 |
PLBD2,HEBP1,ATP8A1,DNAJC3,VAMP8,UGDH,ASS1,JCHAIN,NDRG2,PRKCA,SNX9,RAC3,HMCN1,AARS,STK24,QPRT,TXNDC5,TUBB4A,EPCAM,CPNE2,TGFBR3,TM9SF2,CPVL,PPFIA2,ITGB3,SERINC2,GSTM3,LIN7A,TMED9,GGACT,CPE,ENO1,SLIT2,NEB,PRKACB,ITGB7,GPM6A,CD55,SLC3A2,CEMIP2,WLS,ALDH1L2,DSTN,LRRK2,CAPN5,CR2,PRKAR2B,F12,COTL1,PLEKHA1,GNAI1,AK1,GSN,GPRC5B,NCKAP1L,ENPP6,GNB4,ALDOA,BDH2,SEMA3C,SERPINI1,DNHD1,MLLT3,CRYL1,GNG12,FN1,LGALS3,HID1,PTPRD,GABRB2,CYP2J2,SLK,PHGDH,PFN2,EFEMP1,EEF2,CA2,RPS11,LMAN2,LOXL4,SLCO4C1,STXBP1,GFRA1,CKAP4,RIMS2,RPL26,MID2,QSOX1,RHOQ,PNP,SLC27A2,FASN,PACSIN3,PDE8A,PLS1,C1R,NPC2,CDC42BPA,PLCB1,SLC46A3,CLN5,BAIAP2,MAPKAPK2,VPS37D,GSTO2,RPL28,ADAMTS3,THBS4,FAT1,SH3BP4,MME,SFN,EML5,DNM3,CFH,C4A,MYO1B,COBLL1,COL18A1,CANX,DDR1,PCLO,DOCK2,TIAM2,SCIN,CD53,RIDA,PLPP1,ALDOC,ALDH1L1,MARCKS,PROS1,RPL26L1,RAB27B,GATM,HSPA2,RPS13,CTH,GCA,GAPDH,COL6A2,GARS,TUBA1A,THSD4,PTPN6,ACO1,ADCY1,VIM,GSTO1,ATP1B1,CD40,DSP,FRK,WARS,PATJ,ENTPD1,PTPRJ,PRKCB,LAMB1,PAM,PTPRS,HPGD,LIFR,CNTN1,RPS20,MAN2B2,WASF3,SERINC5,TNIK,MYO1D,ROBO2,ENO2,C1QTNF3,RUSC2,ARL15,EPS8,BLVRB,GAS6,CREB5,EPHB1,SELENOP,NEDD4,RPL34,NKX6-1,MGAT1,GPR155,PRKCD,DSG2,ACTA2,DYNC2H1,MYO6,ESD,RRAS2,SMPDL3A,ATP2B1,CES3,MOB1B,GSTM2,RAB3B,ALDH2,PTPN13,GRID1,MARS,AGAP2,RACK1,SMPDL3B,GPLD1,GALNT3,PTPRC,DDAH1,CD37,FGR,RPL12,FAT4,PLOD2,PRCP,SLC7A5,UACA,RPL4,SLC1A5,CACNA2D1,CRISPLD1,TPT1,STOM |
| 3.530e-02 | -3.34 | AGTCTTA,MIR-499 | MSigDB lists | AGTCTTA,MIR-499 | 69 | 12 | 17377 | 1707 |
ZNF711,KPNA3,ESRRG,PLAG1,REEP1,MPPED2,TMED9,MARCKS,RNF44,ZNF518B,NOVA1,FAM131B |
| 3.530e-02 | -3.34 | GO_PROTEIN_ACTIVATION_CASCADE | MSigDB lists | GO_PROTEIN_ACTIVATION_CASCADE | 69 | 12 | 17377 | 1707 |
CD55,CFH,PRCP,CFHR1,C4A,CR2,C1R,F12,SUSD4,COLEC10,C4BPB,F3 |
| 3.536e-02 | -3.34 | PRKCA (protein kinase C alpha) | protein interactions | 5578 | 271 | 37 | 17029 | 1718 |
PLA2G4A,THOC5,SLC6A9,AKAP5,GABRG2,SELL,NPM1,CHUK,GABRR2,RGS7,PRKCA,CD53,PRKG1,MARCKS,WWC2,STXBP1,SYK,ATP2B1,PDLIM7,GPM6A,PFKFB2,PTPN6,TES,WWC1,SNAP25,RACK1,PLCB1,DSP,MGMT,PRKCB,TERT,EIF4EBP1,PAM,KLF5,PLD1,TRPC3,OCLN |
| 3.544e-02 | -3.34 | human chr8q22.1 | chromosome location | human chr8q22.1 | 42 | 7 | 26185 | 1967 |
LAPTM4B,TMEM67,GEM,FLJ46284,TRIQK,ESRP1,CDH17 |
| 3.546e-02 | -3.34 | GO_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_SECONDARY_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 226 | 31 | 17377 | 1707 |
SLC3A2,SLC6A9,SLC37A1,SLC36A1,SLC36A4,SLC7A2,SLC1A3,SLC12A6,SLC2A13,SLCO3A1,SLC9A7,MCU,SLC7A1,TMCO3,SLC7A11,SLC22A18,SLC16A2,MFSD2A,SLC10A7,SLC2A6,SLC7A5,CDH17,SLCO5A1,SLC2A12,SLC16A9,SLC6A15,SLCO4C1,SLC1A5,SLC9B1,SLC45A3,SLC16A10 |
| 3.548e-02 | -3.34 | GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 457 | 57 | 17377 | 1707 |
TNIK,LATS2,NEK10,AVPI1,ACSL1,DUSP8,FZD8,HERC5,NTRK3,CEBPA,PKN1,TPD52L1,TLR3,IGF1R,PRKCD,GHR,LRP6,DAB2IP,MARCKS,IQGAP3,TLR4,TNFRSF11A,HSPA2,SPRY2,SYK,RASGRP1,PDGFRB,HMGCR,DUSP1,PAK1,SESN2,FZD4,RAPGEF2,PTPN6,TGFA,LRRK2,DUSP9,PRKAR2B,CCNG1,CD40,TLR6,FGFR1,SNCA,MAPKAPK2,TRIB3,PTPRJ,MAP2K6,ERN1,DUSP19,HGF,DIRAS1,TNFSF15,BMP4,MAPK10,SFN,PKIA,ATP2B4 |
| 3.559e-02 | -3.34 | MODULE_175 | MSigDB lists | MODULE_175 | 54 | 10 | 17377 | 1707 |
GPR176,IGF1R,TERT,PLOD2,THBS4,DHCR24,COL18A1,CR2,SP140,HMGCR |
| 3.559e-02 | -3.34 | GO_MONOSACCHARIDE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_MONOSACCHARIDE_BIOSYNTHETIC_PROCESS | 54 | 10 | 17377 | 1707 |
ATF4,GAPDH,ENO2,ALDOC,ALDOA,ATF3,GSTO1,PCK2,PPARGC1A,ENO1 |
| 3.559e-02 | -3.34 | V$AR_03 | MSigDB lists | V$AR_03 | 54 | 10 | 17377 | 1707 |
BDNF,NSD1,KCNH5,ITGA6,JPH1,BCL6,ADCY6,IKZF2,FSTL5,RERE |
| 3.559e-02 | -3.34 | REACTOME_ION_CHANNEL_TRANSPORT | MSigDB lists | REACTOME_ION_CHANNEL_TRANSPORT | 54 | 10 | 17377 | 1707 |
ATP9A,GABRB2,ATP7B,ATP8A1,GABRG2,GABRR2,ATP11A,ATP1B1,ATP10D,ATP1A3 |
| 3.560e-02 | -3.34 | CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I | MSigDB lists | CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I | 367 | 47 | 17377 | 1707 |
TBKBP1,RGS16,SCN5A,ELOVL4,LGR4,KLHL13,LSM11,SLC25A27,BEGAIN,IGF2BP2,SCD,DOCK3,KIF21B,NOVA1,COL14A1,SP8,CCNJ,GALNT1,ZNF362,SEMA4F,ZNF354A,FRAS1,ITGB3,GAN,KLF9,FAM84B,FIGN,C15orf41,RASGRP1,ATP2B1,PAK1,ERGIC1,ACVR1C,PTPRU,FZD4,EDEM3,FNDC3A,ARRDC4,HOXA1,DAGLA,IRS2,RANBP2,CLDN12,ACER2,PGM2L1,ARHGAP28,IQSEC2 |
| 3.563e-02 | -3.33 | GO_EXTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE | MSigDB lists | GO_EXTRINSIC_COMPONENT_OF_PLASMA_MEMBRANE | 133 | 20 | 17377 | 1707 |
FER,GNG12,TNK2,FARP1,ST14,CYTH3,FERMT2,RGS7,FRK,SNX9,GNAI1,FGR,KCNAB1,MCF2L,GNAO1,ERRFI1,ENO1,CDH2,SYK,FES |
| 3.564e-02 | -3.33 | skeletal system development | biological process | GO:0001501 | 458 | 56 | 17256 | 1658 |
CREB3L2,INPPL1,RUNX2,BMPR2,CHSY1,KIAA1217,BCAN,BMP6,COL27A1,TRPS1,SKI,PLS3,IRX5,DLX6,TFAP2A,LRP6,COL19A1,ACVR2A,SH3PXD2B,SERPINH1,COL9A2,ZNF385A,MSX1,SMAD9,NKX3-2,FOXN3,PTPN6,DCHS1,ARID5B,NSD2,SATB2,WNT11,ACVR2B,PLEKHA1,HOXA1,FGFR1,GPLD1,SMAD3,PTPRC,FAT4,INSIG1,FBN1,WDR19,PCGF2,BMP1,HOXD13,DLX2,BMPR1A,BMP4,LRRK1,HOXB9,SHOX2,MMP16,SIX2,PCSK5,MEF2C |
| 3.565e-02 | -3.33 | peptidyl-serine phosphorylation | biological process | GO:0018105 | 170 | 24 | 17256 | 1658 |
PRKAA2,LATS2,MYLK3,LRRK2,CHUK,PRKCQ,GAS6,PKN1,SGK2,PRKCA,MAPKAPK2,PKN3,PRKCB,PLK2,AKT3,PRKCD,ERN1,SGK3,SGK1,PRKG2,MAPK13,MAST4,SYK,MAST1 |
| 3.566e-02 | -3.33 | immunoglobulin receptor binding | molecular function | GO:0034987 | 8 | 3 | 17224 | 1680 |
JCHAIN,FGR,FES |
| 3.573e-02 | -3.33 | human chr5q34 | chromosome location | human chr5q34 | 25 | 5 | 26185 | 1967 |
GABRG2,WWC1,CCNG1,PANK3,GABRB2 |
| 3.575e-02 | -3.33 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | molecular function | GO:0016628 | 26 | 6 | 17224 | 1680 |
DHCR7,BLVRB,SRD5A3,DHCR24,BDH2,FASN |
| 3.576e-02 | -3.33 | GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CARBOHYDRATE_METABOLIC_PROCESS | 158 | 23 | 17377 | 1707 |
PRKAA2,PPP1R3D,SESN2,SORBS1,PDK1,C1QTNF3,IL15,PFKFB2,P2RY1,PHLDA2,LEPR,GPLD1,SNCA,DDIT4,IRS2,RANBP2,ENPP1,PMAIP1,ACER2,GRB10,PPARGC1A,SLC45A3,IGFBP3 |
| 3.576e-02 | -3.33 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN | 158 | 23 | 17377 | 1707 |
RHOBTB1,RNF144A,YPEL2,PRDM1,SNAP25,SLC46A3,PPP1R9A,TMEM132B,RIMKLB,TLR3,PDE10A,SLC7A5,PRELID1,ZBTB20,RTKN2,SLC1A5,VWA5A,STON2,PKIA,PRKACB,RNF152,SLC43A1,SNPH |
| 3.580e-02 | -3.33 | NHL | pfam domains | PF01436 | 8 | 3 | 17054 | 1666 |
TRIM3,TRIM2,PAM |
| 3.580e-02 | -3.33 | CHGN | pfam domains | PF05679 | 8 | 3 | 17054 | 1666 |
CHSY3,CHSY1,B4GALNT3 |
| 3.580e-02 | -3.33 | MH2 | pfam domains | PF03166 | 8 | 3 | 17054 | 1666 |
SMAD3,SMAD9,SMAD6 |
| 3.581e-02 | -3.33 | GSK3B (glycogen synthase kinase 3 beta) | protein interactions | 2932 | 297 | 40 | 17029 | 1718 |
ARHGEF11,HECW2,CEBPA,PRKCA,DYNC1I1,DDIT4,EPB41L3,ERG28,PMAIP1,MYC,PRKCD,SREBF1,SGK3,SGK1,LRP6,PDE4D,YBX3,FKBP14,SNAI2,FZD1,PFKFB4,ATP5IF1,PXN,GAPDH,TUBA1A,MPP1,NFE2L1,DUSP9,ATF3,VIM,MAP1B,SNCA,CEBPB,SMAD3,PRKCB,AKT3,EIF4EBP1,KLF5,PPARGC1A,BTRC |
| 3.583e-02 | -3.33 | GO_CYTOPLASMIC_VESICLE_PART | MSigDB lists | GO_CYTOPLASMIC_VESICLE_PART | 576 | 70 | 17377 | 1707 |
DOC2A,DMXL2,CACNG3,SCAMP1,RNF144A,SYT12,ATP8A1,LDLR,VAMP8,MSR1,SNX9,PCDH7,RND2,ITGB3,RAB26,PROS1,PACSIN1,CLVS2,SYNGR3,RAB27B,MYRIP,CPE,LAMP3,TNK2,TMEM67,ABCC4,FZD4,WLS,TGFA,LRRK2,RAB38,RARRES2,SNCA,GABARAPL1,ARHGAP21,GPRC5B,ENTPD7,ALDOA,AHNAK2,PAM,HGF,ATG5,SV2B,FN1,SEC24D,BACE1,GAS6,SPIRE1,RAB11FIP5,KCNJ4,SREBF1,MARCH3,CADPS2,MYO6,GPR161,SNX7,NOS3,VEGFC,QSOX1,RHOQ,HIP1,PHACTR2,TLR6,ICA1,SH3GL2,RAB31,PTPRN2,TBC1D4,KIF1B,SFN |
| 3.586e-02 | -3.33 | TNFR | smart domains | SM00208 | 23 | 6 | 9493 | 1056 |
TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A |
| 3.589e-02 | -3.33 | V$TEF1_Q6 | MSigDB lists | V$TEF1_Q6 | 209 | 29 | 17377 | 1707 |
PRKAA2,CGN,BDNF,DNM3,USP2,AVPI1,SLC6A9,RASAL2,CACNA1E,SLK,GATA3,CTTNBP2NL,ATP1B1,TNKS1BP1,JAM3,PRRG4,CYP26A1,MAPKAPK2,PTPRJ,PDZD8,C1orf21,TMEM86A,CNNM2,DLG2,LOXL4,PTPRCAP,TSPAN9,KIF1B,RAB30 |
| 3.594e-02 | -3.33 | regulation of cell activation | biological process | GO:0050865 | 514 | 62 | 17256 | 1658 |
TYRO3,LGALS3,IL15,UBASH3B,CD276,LDLR,VAMP8,TNFAIP8L2,TNFSF13B,LILRB1,GATA3,STAT5B,GAS6,SLC7A2,ABAT,PKN1,PRKCA,PIBF1,SPINK5,GATA2,APLF,PRKCD,PRELID1,BCL6,PRKG1,TOX,TLR4,STXBP1,TESPA1,SYK,ZFP36L2,DOCK8,FES,PDGFRB,RASGRP1,NOS3,GAB2,PAK1,FER,VAV3,CD55,PNP,PTPN6,LRRK2,NSD2,PRKCQ,PRDM1,CD40,TLR6,SNCA,CEBPB,IRS2,PTPRC,GSN,FGR,IKZF3,RIPOR2,NCKAP1L,XBP1,BMP4,TNFSF4,MEF2C |
| 3.595e-02 | -3.33 | glycosaminoglycan metabolic process | biological process | GO:0030203 | 153 | 22 | 17256 | 1658 |
UST,CHSY3,GCNT2,CEMIP2,IL15,XYLT1,UGDH,SDC3,PXYLP1,CHSY1,BCAN,GPC6,GLCE,HPSE,HS3ST5,HGF,DSEL,HS3ST3B1,SPOCK3,B4GALT7,PDGFRB,B4GALT6 |
| 3.596e-02 | -3.33 | organonitrogen compound metabolic process | biological process | GO:1901564 | 5382 | 550 | 17256 | 1658 |
GXYLT2,ADAL,PDE1B,PRSS12,AASS,RECK,DNAJC3,ALG1L,STAT5B,CEBPA,CHAC1,NHP2,BCAN,EYA4,FBXO32,TGFBR3,PMAIP1,PPP2R2B,COG3,GGACT,KLHL29,CPE,EIF4E3,SMAD9,KLHL23,LRRK2,HACD1,MSRB3,ABCC2,FGF17,F12,PYCR1,ENPP1,ALDOA,BDH2,MEF2C,CARS,LATS2,SLK,BTBD9,RSL24D1,BACE2,LOXL4,ALPK1,ST8SIA1,NCAM1,MOXD1,GFRA1,RPS23,CHRM3,HMGCR,ENAM,PNP,MGST3,ARID5B,FASN,ST6GALNAC3,C1R,ARRDC4,CLN5,CPEB1,RIMKLB,GSTO2,RPL28,ADAMTS3,QPCTL,FBXO27,CDH2,NUDT10,BTC,GALNT12,GALNT6,C4A,ABHD13,MAPK4,GRK6,COLEC10,SLC19A2,CDS1,PLPP1,TLR3,KMO,EEF1AKMT2,ALDH1L1,PJA1,RPL26L1,PERP,SSH3,MYLK3,GAPDH,GARS,RNF145,ADM2,PFKFB2,KCNH5,ADCY1,WNT11,PXYLP1,RAB38,DSP,ASPH,METAP1D,FGFR1,MAGI3,IRS2,WFS1,PEMT,WWTR1,LAMB1,PAM,P4HA1,ALG11,TNFSF15,KLHL31,SERINC5,GCAT,BACE1,CBS,GAS6,PKN1,EPHB1,TSPAN17,GHR,ZFP36L2,FES,PARP9,TRPM4,OPLAH,RAPGEF2,ELOVL3,RASA3,AK4,RACK1,GALNT3,PTPRC,TRIB3,NSD1,RPL12,PLOD2,AKT3,OSBPL5,XBP1,SRD5A3,NEK11,HK1,BMP4,CMPK2,BTRC,PHC1,TLL2,CCDC126,NMNAT3,TRIM2,FGF13,TRIM16,LMCD1,ASS1,NRN1,MGAT5B,FKBP9,RPS6KA2,CPVL,AADAT,TLR4,ENO1,CD55,MARK1,ATF4,GCNT2,GDPD1,PLPP2,NFE2L1,CR2,DYRK1B,TRIM9,P4HA2,ERN1,CACUL1,HS6ST3,CHMP4C,PRKAA2,LONRF1,TYRO3,UBASH3B,DOK5,PGAP1,EFEMP1,RNF180,GALNT1,NUMBL,PRTFDC1,IGF1R,BCHE,PDE10A,GAN,HS3ST5,ADCY6,BNIP3,MED7,FBXL2,CKAP4,PAK1,CHSY3,FGFR4,MID2,B3GLCT,RNF170,MGAT4B,STRADB,OBSCN,PDE8A,NEGR1,MAPKAPK2,MFSD2A,CSF1,RNF122,TESC,PANK3,MME,PRKN,CFH,LPCAT2,XYLT1,RNF24,NTRK3,SLC7A2,LPIN3,DENND3,KBTBD11,RIDA,ZDHHC6,MYO3B,ZDHHC23,CTH,RPS13,IGFBP3,TMEM67,EVA1A,UROS,PRDM13,THSD4,RNF125,GSTO1,FRK,C4BPB,SMAD3,RANBP2,PTPRJ,RNF217,PTK7,ABI3,PTPRS,MAOA,HGF,SUSD4,MBOAT2,MAN2B2,DYRK3,BMPR2,PAK5,KLHL13,APBB1,BLVRB,USP30,PPP2R3A,FUT9,EIF1,SGK1,PCK2,ESD,SYK,PCSK6,DUSP1,PPP1R3D,NUGGC,NUAK2,SMPDL3B,DDAH1,FBN1,DLG2,MYRF,RPL4,PTGES,MYCBP2,ACVR1,DUSP8,LDLR,GATA3,ADAMTS6,PRKCA,AARS,STK24,HECTD2,MOK,TYMP,CFHR1,PALD1,CHRDL1,NDUFB8,SERINC2,GSTM3,GLDC,GDAP1,KLHL3,ACVR1C,KLHL4,ALDH1L2,DNAJC6,BNIP3L,DESI1,ACVR2B,ZDHHC14,GPC6,SH3RF1,RASGRF2,PLK2,BMP1,B3GALT2,MAPK13,DSEL,SPOCK3,EHHADH,PTPRD,ST6GAL1,DHCR24,MRPL22,SLC1A3,HERC6,TNFRSF19,ADSSL1,CHD5,RPL13A,MECOM,GBGT1,CNTN4,ADCK1,MYC,OPN3,PRKG1,CPXM2,SLC16A9,MAST4,RNF152,QSOX1,RPL26,VLDLR,NSD2,CDC42BPA,MMP15,PKN3,PELI2,MPP2,SMYD3,AMPD1,EPHA3,PLA2G4A,PCSK1N,RASAL2,ELOVL4,RNF144A,ST14,CHUK,NUDT12,DDR1,ZFYVE9,SPEG,ASNS,ALDOC,SCRN1,DAB2IP,PDE4D,SERPINH1,GATM,VNN2,B3GALT1,PDK1,PANK1,PRKCQ,ATP1B1,SNCA,TDO2,PRKCB,CCNA1,MAP3K21,HS3ST3B1,BMPR1A,ATG5,MAPK10,HACE1,RPS20,IGFBP6,HERC5,NEDD4,KDM7A,MGAT1,SGK3,PRKG2,PHYKPL,DYNC2H1,CERS4,SMPDL3A,B4GALT6,GSTM2,HYKK,PTPN13,MPP1,RPL21,ZDHHC15,CTTNBP2NL,UCHL3,GUCY1A2,GPLD1,FGR,PCGF2,PGM2L1,GRIN2D,LRRK1,CERS1,LARP1,DDIT3,B4GALT7,NUDT17,UGT8,PTPN21,UGDH,ABAT,DNER,ABHD4,FKBP11,F3,QPRT,ADPRHL1,PPM1E,EPHB6,GALNT18,PTPRE,IL1RAP,RASGRP1,PDGFRB,PRKACB,TNK2,CEMIP2,CAPN5,ROR1,SGK2,RNF44,GRK3,GSN,AK1,HPSE,OXTR,PCSK5,GPT2,UST,MOCOS,FN1,FBXO4,RIMKLA,ELOVL7,GALNT13,CHSY1,PHGDH,SATB1,RNF141,OTUD1,EEF2,RPS11,CAND2,NOS3,ATP5IF1,IL17RD,RHOQ,PODXL2,GSTM4,EDEM3,DUSP9,SDC3,GALNT17,LHPP,AMDHD1,HERPUD1,GLCE,HK2,PTPRN2,NEK10,IL15,HECW2,PIBF1,SETDB2,ERO1B,CDC14B,RPS6KL1,ACVR2A,FHIT,PROS1,MDH1B,MET,NTNG1,ALG10B,DPP10,FER,GCA,PTPRU,MVD,PTPN6,TTLL7,WARS,TPK1,BCL11A,LMLN,BACH2,EIF4EBP1,TMPRSS9,DUSP19,RNF130,DISP1,PSPH,MAST1,TNIK,ENO2,PRSS16,TSPAN15,NOTUM,RPL34,PRKCD,STC2,TRIM3,MARCH3,IQGAP3,FKBP14,USP2,RAB3B,KDM5B,OGDHL,MARS,GALNT14,PEAK1,DPY19L2,GPR37,ADAMTS17,NACC2,MAP2K6,PRCP,ACER2,CTSV,SLC7A5,RPS12,MMP16,MAP3K20,ABCG1 |
| 3.598e-02 | -3.32 | cEGF | pfam domains | PF12662 | 26 | 6 | 17054 | 1666 |
EFEMP1,GAS6,FBN1,HMCN1,LRP4,MATN2 |
| 3.598e-02 | -3.32 | FERM_C | pfam domains | PF09380 | 26 | 6 | 17054 | 1666 |
EPB41L5,EPB41L3,FARP1,PTPN13,FRMD5,PTPN21 |
| 3.604e-02 | -3.32 | Villin/Gelsolin | interpro domains | IPR007122 | 8 | 3 | 18492 | 1811 |
SVIL,GSN,SCIN |
| 3.604e-02 | -3.32 | SMAD_MH1_sf | interpro domains | IPR036578 | 8 | 3 | 18492 | 1811 |
SMAD3,SMAD9,SMAD6 |
| 3.604e-02 | -3.32 | SMAD_dom_Dwarfin-type | interpro domains | IPR001132 | 8 | 3 | 18492 | 1811 |
SMAD3,SMAD9,SMAD6 |
| 3.604e-02 | -3.32 | MAD_homology_MH1 | interpro domains | IPR013019 | 8 | 3 | 18492 | 1811 |
SMAD3,SMAD9,SMAD6 |
| 3.604e-02 | -3.32 | NHL_repeat | interpro domains | IPR001258 | 8 | 3 | 18492 | 1811 |
TRIM3,TRIM2,PAM |
| 3.604e-02 | -3.32 | Dwarfin | interpro domains | IPR013790 | 8 | 3 | 18492 | 1811 |
SMAD3,SMAD9,SMAD6 |
| 3.604e-02 | -3.32 | Chond_GalNAc | interpro domains | IPR008428 | 8 | 3 | 18492 | 1811 |
CHSY3,CHSY1,B4GALNT3 |
| 3.611e-02 | -3.32 | GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN | 175 | 25 | 17377 | 1707 |
SERINC5,LGALS3,BMPR2,SEC24D,LPCAT2,ZCCHC24,MGAT4B,SPATA13,GATA3,COBLL1,VIM,PRKAR2B,DOCK5,SNX9,ATP10D,GALNT1,MYADM,EIF1,RAP2A,TSC22D1,HPGD,PROS1,SLFN5,NEB,DIRC2 |
| 3.613e-02 | -3.32 | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_DN | 192 | 27 | 17377 | 1707 |
RIN2,IL15,MYO10,CYP2J2,LDLR,LRRCC1,TNFSF13B,MSR1,LILRB1,HERC5,SPATS2L,HERC6,LCP2,DDX60L,HEG1,KIAA1958,CXCL10,TYMP,PIK3AP1,KMO,GBP1,NCOA7,MARCKS,CMPK2,FMNL2,LAMP3,PARP9 |
| 3.613e-02 | -3.32 | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_DN | 192 | 27 | 17377 | 1707 |
MYO1B,JPH1,MFSD6,NPDC1,TNFRSF19,PHLDA2,PPP2R3A,HERPUD1,DCBLD2,EFEMP1,MCOLN2,ABLIM1,RIMKLB,RPS6KA2,MAP2,ITGBL1,RPS6KL1,TSC22D1,MARCKS,ERRFI1,MET,RRAS2,GLIS1,IL1RAP,FOXA1,POU3F3,CRYL1 |
| 3.613e-02 | -3.32 | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN | 192 | 27 | 17377 | 1707 |
PHLDB2,ALDH2,ABCC4,IL15,SEC24D,DOCK1,CKAP2,UGDH,DEPTOR,NPM1,C4orf19,SNX9,NEDD4,NEO1,RAB11FIP5,CPNE2,ICA1,HPSE,RAI14,EEPD1,CNNM2,UNC5B,GFI1,RNF157,AGL,KIAA1549,GAB2 |
| 3.613e-02 | -3.32 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | 192 | 27 | 17377 | 1707 |
PFKFB4,GARS,DYRK3,ENO2,MPP1,VLDLR,IPO5,EPS8,AK4,ADD2,PHGDH,AARS,IL18R1,PGAP1,FAM162A,BATF3,DDIT4,TMEM154,SLC7A11,PMAIP1,GNB4,ALDOC,CCNA1,HK2,BNIP3,ENO1,IL1RAP |
| 3.613e-02 | -3.32 | GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_DN | MSigDB lists | GSE24210_IL35_TREATED_VS_UNTREATED_TCONV_CD4_TCELL_DN | 192 | 27 | 17377 | 1707 |
VAV3,TRIM2,COL4A3,BMPR2,FGF13,NKX3-2,WLS,ITGA6,LRMP,TMTC4,ADAMTS6,P2RY1,LEPR,MCOLN2,RANBP2,IQCH,UNC13B,FAM189A1,TACC2,MARVELD2,P4HA2,CSF1,RCN3,SGK1,MARCKS,IPCEF1,HACE1 |
| 3.613e-02 | -3.32 | GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_UP | MSigDB lists | GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_UP | 192 | 27 | 17377 | 1707 |
PAK1,SLC40A1,ALOX5AP,FAM84A,CRIP2,LRMP,LMCD1,GTF2IRD1,HIP1,ABAT,KIAA1217,CD7,ASPH,COL14A1,GALNT3,EPB41L3,GSN,FKBP9,AK1,LRRN1,ADRB1,TSC22D1,LIMCH1,RNF130,PCOLCE2,CDH2,CTNND2 |
| 3.615e-02 | -3.32 | DKKL1 (dickkopf like acrosomal protein 1) | protein interactions | 27120 | 75 | 13 | 17029 | 1718 |
PCSK1N,COL6A2,TGFBR3,CELSR1,FAT4,CELSR3,FAT1,FRAS1,UGDH,MGAT4B,PAM,LRP6,PCDH7 |
| 3.619e-02 | -3.32 | JIANG_VHL_TARGETS | MSigDB lists | JIANG_VHL_TARGETS | 125 | 19 | 17377 | 1707 |
SLC3A2,ENO2,EBPL,ZNF395,TES,RPL21,NFE2L1,NPM1,COTL1,SPATS2L,CANX,STK24,SLC7A5,UACA,RNF130,RPL26L1,ERRFI1,CKAP4,IGFBP3 |
| 3.621e-02 | -3.32 | Fatty acid biosynthesis, elongation, endoplasmic reticulum | KEGG pathways | hsa_M00415 | 13 | 4 | 7161 | 730 |
ELOVL4,ELOVL7,ELOVL3,HACD1 |
| 3.621e-02 | -3.32 | Fatty acid biosynthesis, elongation, endoplasmic reticulum | KEGG pathways | M00415 | 13 | 4 | 7161 | 730 |
ELOVL4,ELOVL7,ELOVL3,HACD1 |
| 3.628e-02 | -3.32 | DWA | smart domains | SM00523 | 12 | 4 | 9493 | 1056 |
SMAD3,SMAD9,SMAD6,NFIA |
| 3.628e-02 | -3.32 | ZnF_GATA | smart domains | SM00401 | 12 | 4 | 9493 | 1056 |
GATA3,GATA2,RERE,TRPS1 |
| 3.629e-02 | -3.32 | HUANG_DASATINIB_RESISTANCE_UP | MSigDB lists | HUANG_DASATINIB_RESISTANCE_UP | 77 | 13 | 17377 | 1707 |
GNG12,ANTXR2,POPDC3,MYO10,RAI14,KCTD12,COTL1,MET,INPP1,SNAI2,PCDH7,F3,DCBLD2 |
| 3.629e-02 | -3.32 | GO_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION | MSigDB lists | GO_REGULATION_OF_STRIATED_MUSCLE_CONTRACTION | 77 | 13 | 17377 | 1707 |
TRPM4,SCN5A,GSTM2,ANK2,DSG2,PKP2,RYR2,GSTO1,PDE4D,ATP1B1,ASPH,DSP,NOS1AP |
| 3.629e-02 | -3.32 | GHANDHI_BYSTANDER_IRRADIATION_UP | MSigDB lists | GHANDHI_BYSTANDER_IRRADIATION_UP | 77 | 13 | 17377 | 1707 |
SLC39A14,PLA2G4A,CXCL10,SLC7A11,POPDC3,LRRC8B,SLC39A8,GJB2,MCTP2,SLC6A15,CREB5,TESC,PTGES |
| 3.630e-02 | -3.32 | ST7L (suppression of tumorigenicity 7 like) | protein interactions | 54879 | 19 | 5 | 17029 | 1718 |
PCDHB7,RNF170,SLC39A8,MCOLN3,KCNS3 |
| 3.630e-02 | -3.32 | PXMP2 (peroxisomal membrane protein 2) | protein interactions | 5827 | 19 | 5 | 17029 | 1718 |
TMCO3,SLC6A15,GPM6A,TTC30B,MME |
| 3.630e-02 | -3.32 | RIPK4 (receptor interacting serine/threonine kinase 4) | protein interactions | 54101 | 19 | 5 | 17029 | 1718 |
VWA5A,PRKCB,ENPP6,PRKCD,BTRC |
| 3.630e-02 | -3.32 | LYPD1 (LY6/PLAUR domain containing 1) | protein interactions | 116372 | 19 | 5 | 17029 | 1718 |
COL6A2,TUBA1A,RAB6B,VWDE,PCSK5 |
| 3.630e-02 | -3.32 | ASB15 (ankyrin repeat and SOCS box containing 15) | protein interactions | 142685 | 19 | 5 | 17029 | 1718 |
SVIL,VIM,GAPDH,AGL,IPO5 |
| 3.630e-02 | -3.32 | HGF (hepatocyte growth factor) | protein interactions | 3082 | 19 | 5 | 17029 | 1718 |
HGF,NRP1,MET,FN1,ST14 |
| 3.630e-02 | -3.32 | IKZF2 (IKAROS family zinc finger 2) | protein interactions | 22807 | 19 | 5 | 17029 | 1718 |
LONRF1,CTBP2,IKZF3,IKZF5,IKZF2 |
| 3.630e-02 | -3.32 | KRT79 (keratin 79) | protein interactions | 338785 | 19 | 5 | 17029 | 1718 |
BAG3,INPPL1,LGR4,UBASH3B,BTRC |
| 3.630e-02 | -3.32 | calcium ion transport into cytosol | biological process | GO:0060402 | 63 | 11 | 17256 | 1658 |
PTPRC,JPH1,RASA3,RYR2,GRIN2D,ITPR2,FAM155B,FAM155A,CACNA2D1,ATP2B4,DDIT3 |
| 3.632e-02 | -3.32 | Type 2 diabetes(PMID:21490949) | GWAS genes | Type 2 diabetes(PMID:21490949) | 12 | 5 | 2388 | 399 |
CR2,PCNX2,PLS1,PEX5L,TCERG1L |
| 3.633e-02 | -3.32 | DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_DN | MSigDB lists | DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_DN | 8 | 3 | 17377 | 1707 |
ID3,GAPDH,ID1 |
| 3.633e-02 | -3.32 | GAUTSCHI_SRC_SIGNALING | MSigDB lists | GAUTSCHI_SRC_SIGNALING | 8 | 3 | 17377 | 1707 |
ID3,ID1,SMAD6 |
| 3.633e-02 | -3.32 | KOINUMA_COLON_CANCER_MSI_DN | MSigDB lists | KOINUMA_COLON_CANCER_MSI_DN | 8 | 3 | 17377 | 1707 |
LAPTM4B,PMEPA1,QPRT |
| 3.633e-02 | -3.32 | PHONG_TNF_TARGETS_DN | MSigDB lists | PHONG_TNF_TARGETS_DN | 8 | 3 | 17377 | 1707 |
ID1,SNCA,HEY1 |
| 3.633e-02 | -3.32 | MIKKELSEN_DEDIFFERENTIATED_STATE_UP | MSigDB lists | MIKKELSEN_DEDIFFERENTIATED_STATE_UP | 8 | 3 | 17377 | 1707 |
COBL,DSG2,PHC1 |
| 3.633e-02 | -3.32 | GO_FATTY_ACID_ELONGATION | MSigDB lists | GO_FATTY_ACID_ELONGATION | 8 | 3 | 17377 | 1707 |
ELOVL4,ELOVL7,ELOVL3 |
| 3.633e-02 | -3.32 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | 8 | 3 | 17377 | 1707 |
TRIB3,NR4A1,DDIT3 |
| 3.633e-02 | -3.32 | BENPORATH_OCT4_TARGETS | MSigDB lists | BENPORATH_OCT4_TARGETS | 270 | 36 | 17377 | 1707 |
SORBS1,CNTNAP3,RNF24,ZIC2,PHGDH,GAS1,PPP2R3A,TRPS1,CA2,KCNN2,EOMES,LRRN1,CDC14B,ZDHHC6,TSC22D1,GLDC,PAK1,MEIS2,KLHL4,FEZ1,CBY1,LHPP,ROR1,LRAT,FGFR1,DKK1,ZIC1,SFXN1,ENTPD1,TCF7L1,MSC,KCNMB4,RASGRF2,MCC,KLF5,CACNA2D1 |
| 3.638e-02 | -3.31 | Glutathione_S-Trfase_N | interpro domains | IPR004045 | 26 | 6 | 18492 | 1811 |
GSTM3,GDAP1,GSTO1,GSTM2,GSTO2,GSTM4 |
| 3.638e-02 | -3.31 | cEGF | interpro domains | IPR026823 | 26 | 6 | 18492 | 1811 |
EFEMP1,GAS6,FBN1,HMCN1,LRP4,MATN2 |
| 3.639e-02 | -3.31 | extracellular vesicle | cellular component | GO:1903561 | 2140 | 226 | 18223 | 1724 |
PLBD2,HEBP1,ATP8A1,DNAJC3,VAMP8,UGDH,ASS1,JCHAIN,NDRG2,PRKCA,SNX9,RAC3,HMCN1,AARS,STK24,QPRT,TXNDC5,TUBB4A,EPCAM,CPNE2,TGFBR3,TM9SF2,CPVL,PPFIA2,ITGB3,SERINC2,GSTM3,LIN7A,TMED9,GGACT,CPE,ENO1,SLIT2,NEB,PRKACB,ITGB7,GPM6A,CD55,SLC3A2,CEMIP2,WLS,ALDH1L2,DSTN,LRRK2,CAPN5,CR2,PRKAR2B,F12,COTL1,PLEKHA1,GNAI1,AK1,GSN,GPRC5B,NCKAP1L,ENPP6,GNB4,ALDOA,BDH2,SEMA3C,SERPINI1,DNHD1,MLLT3,CRYL1,GNG12,FN1,LGALS3,HID1,PTPRD,GABRB2,CYP2J2,SLK,PHGDH,PFN2,EFEMP1,EEF2,CA2,RPS11,LMAN2,LOXL4,SLCO4C1,STXBP1,GFRA1,CKAP4,RIMS2,RPL26,MID2,QSOX1,RHOQ,PNP,SLC27A2,FASN,PACSIN3,PDE8A,PLS1,C1R,NPC2,CDC42BPA,ARRDC4,PLCB1,SLC46A3,CLN5,BAIAP2,MAPKAPK2,VPS37D,GSTO2,RPL28,ADAMTS3,THBS4,FAT1,SH3BP4,MME,SFN,EML5,DNM3,CFH,C4A,MYO1B,COL18A1,COBLL1,CANX,DDR1,PCLO,DOCK2,TIAM2,SCIN,CD53,RIDA,PLPP1,ALDOC,ALDH1L1,MARCKS,PROS1,RPL26L1,RAB27B,GATM,HSPA2,RPS13,CTH,GCA,GAPDH,COL6A2,GARS,TUBA1A,THSD4,PTPN6,ACO1,ADCY1,VIM,GSTO1,ATP1B1,CD40,DSP,FRK,WARS,PATJ,ENTPD1,PTPRJ,PRKCB,LAMB1,PAM,PTPRS,HPGD,LIFR,CNTN1,RPS20,MAN2B2,WASF3,SERINC5,TNIK,MYO1D,ROBO2,ENO2,C1QTNF3,RUSC2,ARL15,EPS8,BLVRB,GAS6,CREB5,EPHB1,SELENOP,NEDD4,RPL34,NKX6-1,MGAT1,GPR155,PRKCD,DSG2,ACTA2,DYNC2H1,MYO6,ESD,RRAS2,SMPDL3A,ATP2B1,CES3,MOB1B,GSTM2,RAB3B,ALDH2,PTPN13,GRID1,MARS,AGAP2,RACK1,SMPDL3B,GPLD1,GALNT3,PTPRC,DDAH1,CD37,FGR,RPL12,FAT4,PLOD2,PRCP,SLC7A5,UACA,RPL4,SLC1A5,CACNA2D1,CRISPLD1,TPT1,ATP1A3,STOM |
| 3.644e-02 | -3.31 | GATAZNFINGER | prints domains | PR00619 | 8 | 3 | 4652 | 458 |
GATA3,GATA2,TRPS1 |
| 3.644e-02 | -3.31 | GELSOLIN | prints domains | PR00597 | 8 | 3 | 4652 | 458 |
SVIL,GSN,SCIN |
| 3.644e-02 | -3.31 | positive regulation of developmental growth | biological process | GO:0048639 | 179 | 25 | 17256 | 1658 |
PAK1,PRKN,BDNF,FN1,BMPR2,YAP1,PLS1,STAT5B,NTRK3,ZFPM2,PLCB1,FGFR1,MAP1B,RND2,TGFBR3,CSF1,GHR,BMPR1A,SH3PXD2B,YBX3,NRP1,SHTN1,RIMS2,GLI1,MEF2C |
| 3.646e-02 | -3.31 | Fc epsilon RI signaling pathway | KEGG pathways | hsa04664 | 67 | 12 | 7161 | 730 |
PLA2G4A,VAV3,ALOX5AP,MAP2K6,AKT3,MAPK13,PRKCA,LCP2,MAPK10,SYK,RAC3,GAB2 |
| 3.646e-02 | -3.31 | Fc epsilon RI signaling pathway | KEGG pathways | ko04664 | 67 | 12 | 7161 | 730 |
PLA2G4A,VAV3,ALOX5AP,MAP2K6,AKT3,MAPK13,PRKCA,LCP2,MAPK10,SYK,RAC3,GAB2 |
| 3.649e-02 | -3.31 | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 846 | 99 | 17377 | 1707 |
NEK10,AVPI1,IL15,AKAP5,LMCD1,GATA3,CHUK,NTRK3,PRKCA,PIBF1,NOS1AP,F3,TLR3,PMAIP1,DAB2IP,TLR4,RASGRP1,PDGFRB,CTH,IGFBP3,CYP1B1,GCNT2,FZD4,WLS,PTPN6,TGFA,LRRK2,PRKCQ,GSTO1,WNT11,CD40,ASPH,FGFR1,CXCL10,PTPRJ,GPRC5B,HPSE,PRKCB,PLK2,ERN1,TNFRSF1A,ADRB1,DUSP19,BBC3,TNFSF15,HGF,DIRAS1,UNC5B,NRP1,MAPK10,MID1,RRAGD,TNIK,EDA2R,REL,FZD8,SORBS3,P2RY1,GAS6,PKN1,NDFIP2,TPD52L1,TNFRSF19,CHD5,IL18R1,NEDD4,PIK3AP1,MCF2L,RASD2,GHR,IQGAP3,TNFRSF11A,SPRY2,SYK,ZNF385A,HMGCR,FGFR4,PAK1,MID2,MSX1,GSTM2,RAPGEF2,LITAF,DUSP9,WWC1,TLR6,PLCB1,GPR37,MAPKAPK2,FGR,NACC2,CSF1,MAP2K6,PELI2,XBP1,LRRK1,BMP4,CDH2,DDIT3 |
| 3.652e-02 | -3.31 | GO_ADENYL_NUCLEOTIDE_BINDING | MSigDB lists | GO_ADENYL_NUCLEOTIDE_BINDING | 1444 | 162 | 17377 | 1707 |
NMNAT3,MVK,ACVR1,ACSL1,KIF5A,ATP8A1,ASS1,PRKCA,AARS,STK24,MOK,BAG3,RPS6KA2,DNAH6,EPHB6,PRKACB,PDGFRB,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ROR1,ACVR2B,SGK2,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,PIK3C2B,MAPK13,PRKAA2,CARS,TYRO3,LATS2,RUNX2,BVES,SCN8A,SLK,RIMKLA,PFN2,CHD5,GRPEL2,HSPA12B,IGF1R,ABCA5,ADCK1,PDE10A,HS3ST5,PRKG1,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,SLC27A2,MYO10,RAPGEF4,OBSCN,STRADB,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,HK2,SLFN5,PANK3,ACSM3,EPHA3,NEK10,MYO1B,CHUK,MAPK4,NTRK3,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,MET,DNAH5,HSPA2,FER,MYLK3,GARS,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,TTLL7,FRK,ATP10D,MAGI3,FGFR1,TPK1,WARS,ENTPD1,PRKCB,PTK7,BMPR1A,MAPK10,MAST1,TNIK,MYO1D,DYRK3,BMPR2,ATP9A,NLRP14,KIF5C,P2RY1,EPHB1,PKN1,EHD3,PRKCD,SGK3,GTF2F2,PRKG2,SGK1,ACTA2,DYNC2H1,MYO6,SYK,ATP2B1,FES,PFKFB4,TRPM4,OPLAH,RAPGEF2,NUAK2,AK4,MARS,ATP11A,PEAK1,TRIB3,FGR,MAP2K6,AKT3,NEK11,PIP5KL1,KIF21A,LRRK1,HK1,CMPK2,KIF1B,ATP2B4,ATP1A3,ABCG1 |
| 3.661e-02 | -3.31 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | 150 | 22 | 17377 | 1707 |
RHOQ,ACSL1,ID1,PNRC1,LILRB1,HERC5,SPATS2L,SLC1A3,DDR1,JAM3,TPK1,QPRT,HOMER3,TRIB3,SLC7A11,PLK2,PIK3C2B,PLTP,IL1RAP,LRP3,RASGRP1,RRAGD |
| 3.665e-02 | -3.31 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | 117 | 18 | 17377 | 1707 |
TBC1D1,PREX1,HECW2,PHACTR2,SATB2,COTL1,PHLDA2,EML1,HOMER3,MECOM,CHN1,SLC7A11,PLAGL1,GTSF1,RAB31,TFAP2A,MARCH3,SERPINI1 |
| 3.675e-02 | -3.30 | PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases | REACTOME pathways | R-HSA-8849471 | 27 | 6 | 10287 | 971 |
RASA3,DAB2IP,PXN,SPRED3,RASAL2,DOCK1 |
| 3.676e-02 | -3.30 | inclusion body | cellular component | GO:0016234 | 80 | 13 | 18223 | 1724 |
RANBP2,PRKN,KLF8,FGR,ATF4,EEF2,LRRK2,STRADB,PRKCQ,AGL,SERGEF,HERPUD1,SNCA |
| 3.685e-02 | -3.30 | GO_REGULATION_OF_NEURON_MIGRATION | MSigDB lists | GO_REGULATION_OF_NEURON_MIGRATION | 26 | 6 | 17377 | 1707 |
NKX6-1,DAB2IP,NRG3,SEMA3A,RAPGEF2,SEMA6A |
| 3.685e-02 | -3.30 | PID_ALK1_PATHWAY | MSigDB lists | PID_ALK1_PATHWAY | 26 | 6 | 17377 | 1707 |
ACVR2A,ACVR2B,ACVR1,ID1,SMAD9,BMPR2 |
| 3.685e-02 | -3.30 | VALK_AML_CLUSTER_1 | MSigDB lists | VALK_AML_CLUSTER_1 | 26 | 6 | 17377 | 1707 |
COBLL1,ATF3,PRR16,MECOM,MEF2C,TRPS1 |
| 3.685e-02 | -3.30 | IKEDA_MIR30_TARGETS_DN | MSigDB lists | IKEDA_MIR30_TARGETS_DN | 26 | 6 | 17377 | 1707 |
PRICKLE1,PCDH10,SATB2,NCAM1,ESRRG,PANK1 |
| 3.685e-02 | -3.30 | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_UP | MSigDB lists | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_UP | 26 | 6 | 17377 | 1707 |
CBS,C1R,GRB10,CCNG1,C9orf116,CD53 |
| 3.685e-02 | -3.30 | WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 | MSigDB lists | WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 | 26 | 6 | 17377 | 1707 |
TRIB3,GAPDH,EHHADH,ENO1,ALDOA,ELOVL3 |
| 3.685e-02 | -3.30 | KEGG_O_GLYCAN_BIOSYNTHESIS | MSigDB lists | KEGG_O_GLYCAN_BIOSYNTHESIS | 26 | 6 | 17377 | 1707 |
GALNT3,GALNT13,GALNT1,GALNT14,GALNT6,GALNT12 |
| 3.685e-02 | -3.30 | GO_HETEROTYPIC_CELL_CELL_ADHESION | MSigDB lists | GO_HETEROTYPIC_CELL_CELL_ADHESION | 26 | 6 | 17377 | 1707 |
PKP2,ITGB7,DSP,DSG2,PERP,ITGB3 |
| 3.685e-02 | -3.30 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_HEPARAN_SULFATE | 26 | 6 | 17377 | 1707 |
HS3ST3B1,XYLT1,B4GALT7,HS3ST5,HS6ST3,GLCE |
| 3.685e-02 | -3.30 | GO_GLUTAMATE_SECRETION | MSigDB lists | GO_GLUTAMATE_SECRETION | 26 | 6 | 17377 | 1707 |
SLC1A3,SNAP25,APBA1,UNC13B,STXBP1,PPFIA2 |
| 3.685e-02 | -3.30 | GO_NEGATIVE_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 837 | 98 | 17377 | 1707 |
BTC,ACVR1,ID1,GRIK2,DNAJC3,GATA3,LILRB1,NPM1,STAT5B,NTRK3,PRKCA,AARS,TXNDC5,EPCAM,BAG3,ASNS,BCL6,CTTN,MET,POU3F3,DOCK8,PDGFRB,SNAI2,CTH,LAMP3,PRAME,ATF4,WISP3,NKX3-2,LRRK2,BNIP3L,YAP1,PRKCQ,WNT11,ATOH1,SNCA,PYCR1,SMAD3,IRS2,NCKAP1L,SH3RF1,PLK2,WFS1,ERCC5,HGF,ATG5,UNC5B,NRP1,PPARGC1A,LIFR,MEF2C,PRKAA2,BCL11B,TYRO3,FN1,LGALS3,REL,GABRB2,ITGA6,ST6GAL1,DHCR24,GAS6,MECOM,SYCP2,BNIP1,IGF1R,MYC,PRKCD,PRELID1,TFAP2A,LRP6,SGK1,BNIP3,STXBP1,SMAD6,SPRY2,ZNF385A,DUSP1,HMGCR,NOS3,BDNF,SLC40A1,MSX1,FHL2,NUAK2,STRADB,AGAP2,ZFPM2,HERPUD1,MGMT,GPR37,CEBPB,TERT,XBP1,PCGF2,BMP4,SFN,TPT1 |
| 3.687e-02 | -3.30 | REACTOME_PEPTIDE_CHAIN_ELONGATION | MSigDB lists | REACTOME_PEPTIDE_CHAIN_ELONGATION | 85 | 14 | 17377 | 1707 |
RPS20,RPL26,RPL12,EEF2,RPL28,RPS11,RPL21,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPL34,RPS13 |
| 3.687e-02 | -3.30 | V$PAX3_B | MSigDB lists | V$PAX3_B | 85 | 14 | 17377 | 1707 |
BCL11B,ZNF711,ZNF362,PNRC1,NR4A1,TMEM86A,ZNF521,CNNM2,ACVR2A,AGAP2,DLG2,GEM,CANX,SEMA3A |
| 3.687e-02 | -3.30 | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP | MSigDB lists | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP | 85 | 14 | 17377 | 1707 |
ID3,FGR,IL32,TUBA1A,DSTN,PTPN6,SLC7A5,TSC22D1,GATA3,SELL,MYOM2,VIM,LCP2,MME |
| 3.687e-02 | -3.30 | TIEN_INTESTINE_PROBIOTICS_2HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_2HR_DN | 85 | 14 | 17377 | 1707 |
DBN1,MICAL2,CRIM1,PRCP,FLRT3,RAPGEF2,WWTR1,FERMT2,INPP5F,HOXA1,CEBPD,CKAP4,FKBP11,GAB2 |
| 3.691e-02 | -3.30 | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 660 | 79 | 17377 | 1707 |
THOC5,GRIK2,DNAJC3,NPM1,NTRK3,STK24,BAG3,TLR3,PMAIP1,DACT1,RAP2A,BCL6,DAB2IP,CTTN,MET,TLR4,RASGRP1,SNAI2,GAPDH,ATF4,FZD4,LRRK2,BNIP3L,FEZ1,MAGI3,SNCA,PYCR1,RANBP2,SH3RF1,WFS1,ERN1,DUSP19,BBC3,HGF,INPP5F,BMPR1A,ATG5,MID1,LZTS1,PRKAA2,TNIK,EDA2R,FZD8,APBB1,UBAC2,ATP6V1E2,PKN1,EPHB1,TPD52L1,TNFRSF19,NEDD4,MECOM,IGF1R,MYC,PRKCD,SREBF1,BNIP3,FIGN,TNFRSF11A,SYK,ZNF385A,HMGCR,PAK1,QSOX1,MSX1,TLR6,PLCB1,HERPUD1,MGMT,GPR37,MAPKAPK2,TEX15,RPL28,NACC2,TERT,XBP1,DDIT3,LARP1,TPT1 |
| 3.694e-02 | -3.30 | Regulation of actin cytoskeleton | KEGG pathways | hsa04810 | 211 | 30 | 7161 | 730 |
FGFR4,PAK1,ITGB7,VAV3,SSH3,GNG12,PXN,MYLK3,FN1,FGF13,PAK5,DOCK1,ITGA6,FGF12,SPATA13,ENAH,FGF17,PFN2,RAC3,BAIAP2,FGFR1,SCIN,GSN,NCKAP1L,ITGA2,ITGB3,IQGAP3,RRAS2,CHRM3,PDGFRB |
| 3.694e-02 | -3.30 | Regulation of actin cytoskeleton | KEGG pathways | ko04810 | 211 | 30 | 7161 | 730 |
FGFR4,PAK1,ITGB7,VAV3,SSH3,GNG12,PXN,MYLK3,FN1,FGF13,PAK5,DOCK1,ITGA6,FGF12,SPATA13,ENAH,FGF17,PFN2,RAC3,BAIAP2,FGFR1,SCIN,GSN,NCKAP1L,ITGA2,ITGB3,IQGAP3,RRAS2,CHRM3,PDGFRB |
| 3.694e-02 | -3.30 | Immune reponse to smallpox (secreted IFN-alpha)(PMID:22610502) | GWAS genes | Immune reponse to smallpox (secreted IFN-alpha)(PMID:22610502) | 20 | 7 | 2388 | 399 |
SGK1,TENM1,ZNF827,KCND3,COL4A4,ATP8A1,LPP |
| 3.696e-02 | -3.30 | interaction with host | biological process | GO:0051701 | 162 | 23 | 17256 | 1658 |
EFNB2,TYRO3,PRKN,ITGB7,THOC5,CD55,GAPDH,LDLR,VAMP8,CR2,NTRK3,GAS6,NEDD4,SMAD3,GPR15,KPNA3,ITGB3,ITGA2,MET,SLC1A5,NCAM1,THOC3,LAMP3 |
| 3.697e-02 | -3.30 | eye-uveal_tract-malignant_melanoma | COSMIC cancer mutations | eye-uveal_tract-malignant_melanoma | 151 | 22 | 17385 | 1698 |
SESN2,PDE1B,FHDC1,NPM1,NTRK3,CEBPA,SFXN3,SESN1,SNX9,TTC28,MLC1,PCLO,HMCN1,CA13,FGFR1,PTPRC,TERT,TUFT1,MET,TSHR,ACSM3,SNX7 |
| 3.698e-02 | -3.30 | ubiquitin conjugating enzyme binding | molecular function | GO:0031624 | 33 | 7 | 17224 | 1680 |
RNF125,LONRF1,RNF180,PRKN,RNF217,RNF144A,RASD2 |
| 3.699e-02 | -3.30 | MODULE_321 | MSigDB lists | MODULE_321 | 109 | 17 | 17377 | 1707 |
TRDMT1,DYRK3,PXN,LPCAT2,WLS,ACO1,FERMT2,CBS,COL18A1,SPATS2L,DCBLD2,MYC,SLC1A5,PTPRE,SNAI2,CKAP4,GLDC |
| 3.699e-02 | -3.30 | WOOD_EBV_EBNA1_TARGETS_UP | MSigDB lists | WOOD_EBV_EBNA1_TARGETS_UP | 109 | 17 | 17377 | 1707 |
TYRO3,CHN1,INHBC,BAG3,NELL2,TUBA1A,TRIM16,GSTM4,MYC,UGDH,OPN3,FASN,ASS1,SERPINH1,INPP1,SLCO3A1,SIX2 |
| 3.703e-02 | -3.30 | plasma membrane bounded cell projection cytoplasm | cellular component | GO:0032838 | 182 | 25 | 18223 | 1724 |
GRIK2,WLS,KIF5A,LRRK2,SYBU,ABHD13,EFHC1,CANX,SPATA7,BAIAP2,GABARAPL1,TUBB4A,ARMC4,KCNAB1,MAP1A,DNAH6,MAP2,DYNC2LI1,DLG2,DYNC2H1,ATG5,DNHD1,DNAH5,KIF1B,GLI1 |
| 3.705e-02 | -3.30 | hexose biosynthetic process | biological process | GO:0019319 | 48 | 9 | 17256 | 1658 |
GAPDH,ATF4,ENO2,ALDOC,ALDOA,ATF3,PPARGC1A,PCK2,ENO1 |
| 3.705e-02 | -3.30 | face development | biological process | GO:0060324 | 48 | 9 | 17256 | 1658 |
MSX1,ARID5B,LRP6,PLEKHA1,PAX9,ASPH,CRISPLD1,DKK1,SKI |
| 3.705e-02 | -3.30 | negative regulation of Ras protein signal transduction | biological process | GO:0046580 | 48 | 9 | 17256 | 1658 |
RIPOR2,RASAL2,BCL6,RASA3,DAB2IP,SPRY4,MET,SPRY2,ARHGAP44 |
| 3.705e-02 | -3.30 | positive regulation of pathway-restricted SMAD protein phosphorylation | biological process | GO:0010862 | 48 | 9 | 17256 | 1658 |
ACVR2A,INHBC,BMPR1A,BMP4,ACVR1,BMPR2,MSTN,BMP6,INHBE |
| 3.707e-02 | -3.29 | cellular response to hexose stimulus | biological process | GO:0071331 | 71 | 12 | 17256 | 1658 |
PRKAA2,IRS2,RAB11FIP5,IGF1R,UNC13B,XBP1,ERN1,PTPRN2,GAS6,RACK1,PCK2,PPARGC1A |
| 3.707e-02 | -3.29 | regulation of vesicle fusion | biological process | GO:0031338 | 71 | 12 | 17256 | 1658 |
TRIM9,ADPRHL1,TBC1D8B,TBC1D1,STXBP6,TBC1D9,TBC1D4,TBC1D16,STXBP1,TBC1D30,TBC1D8,TBC1D2 |
| 3.709e-02 | -3.29 | GO_ANTERIOR_POSTERIOR_AXIS_SPECIFICATION | MSigDB lists | GO_ANTERIOR_POSTERIOR_AXIS_SPECIFICATION | 47 | 9 | 17377 | 1707 |
EPB41L5,WLS,LRP6,BMP4,PGAP1,SIX2,DDIT3,SKI,PCSK6 |
| 3.710e-02 | -3.29 | GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 167 | 24 | 17377 | 1707 |
ATF4,LANCL3,TES,STAT4,FAM102B,IGF2BP2,PRKAR2B,SLC7A2,PLEKHA1,CD40,LCP2,SLCO3A1,CBLN1,HEG1,CEBPB,MAPKAPK2,PTPRJ,KMO,FLRT3,PRKCD,GSTM3,CMPK2,RAPGEF5,LPP |
| 3.710e-02 | -3.29 | GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_UP | MSigDB lists | GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_UP | 167 | 24 | 17377 | 1707 |
MAN2B2,GPM6A,TRIM2,ZNF395,CHCHD7,ST14,PTPN6,PHACTR2,COTL1,WDFY4,ZDHHC14,ASPH,JAM3,RPS6KA2,FCHO2,PMEPA1,PRKCB,BCL6,RAI14,CLMN,NAP1L3,CERS4,TBC1D9,TPM1 |
| 3.710e-02 | -3.29 | NOTCH_DN.V1_DN | MSigDB lists | NOTCH_DN.V1_DN | 167 | 24 | 17377 | 1707 |
DOC2A,VNN2,MYO1D,ID1,GPR65,DNAJC3,LRP4,NSUN6,CR2,CA8,BAIAP2,ZSCAN5A,RASSF8,GPR15,CA2,LHX6,POF1B,MAPK13,SPRY4,SP140,PPARGC1A,SUSD4,TRPC3,FMNL2 |
| 3.710e-02 | -3.29 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | 167 | 24 | 17377 | 1707 |
MOB1B,SLC3A2,DYRK3,ACVR1,TMEM65,TCEAL3,ATF3,SNX9,ASPH,SLC19A2,TBC1D2,ZSCAN5A,CEBPB,BAG3,CSF1,TSC22D1,SGK1,TNFSF15,MAPK13,GEM,PTPRE,SPRY2,DDIT3,RRAGD |
| 3.711e-02 | -3.29 | myelin assembly | biological process | GO:0032288 | 20 | 5 | 17256 | 1658 |
EPB41L3,UGT8,FIG4,ANK2,AHNAK2 |
| 3.711e-02 | -3.29 | positive regulation of signal transduction by p53 class mediator | biological process | GO:1901798 | 20 | 5 | 17256 | 1658 |
RPL26,MSX1,PMAIP1,CHD5,ZNF385A |
| 3.711e-02 | -3.29 | middle ear morphogenesis | biological process | GO:0042474 | 20 | 5 | 17256 | 1658 |
MSX1,INSIG1,NKX3-2,FGFR1,SIX2 |
| 3.712e-02 | -3.29 | GO_SINGLE_ORGANISM_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_SINGLE_ORGANISM_BIOSYNTHETIC_PROCESS | 1244 | 141 | 17377 | 1707 |
NMNAT3,UGT8,MVK,ACSL1,ADAL,UGDH,ASS1,CEBPA,ABAT,NHP2,BCAN,CHST10,QPRT,CYP51A1,TYMP,GSTM3,TRPC1,PLTP,ENO1,PDGFRB,GCNT2,ATF4,NFE2L1,FGF17,GPC6,PYCR1,AK1,INSIG1,ALDOA,BDH2,B3GALT2,PIK3C2B,DSEL,INPP5F,PPARGC1A,CRYL1,HS6ST3,UST,GPT2,PRKAA2,MOCOS,INPPL1,ALOX5AP,ELOVL7,DHCR24,OLAH,MRPL22,SCD,ISYNA1,CHSY1,SLC1A3,PHGDH,ADSSL1,PGAP1,GBGT1,PRTFDC1,EEF2,MSMO1,SREBF1,HS3ST5,ADCY6,ST8SIA1,AGL,HMGCR,FGFR4,CHSY3,FADS1,PNP,SLC27A2,GSTM4,MGST3,FASN,CALCRL,SDC3,ST6GALNAC3,LHPP,GLCE,GSTO2,ADAMTS3,SQLE,PLD1,DHCR7,PANK3,AMPD1,ACSM3,TFCP2L1,PLA2G4A,ELOVL4,LPCAT2,XYLT1,LPIN3,TNKS1BP1,CDS1,ASNS,IDI1,KMO,ALDOC,SERPINH1,GATM,ALG10B,CTH,B3GALT1,GAPDH,GARS,UROS,CYB5R2,MVD,PANK1,ADCY1,ATF3,GSTO1,FGFR1,IRS2,PEMT,INPP4B,HS3ST3B1,MBOAT2,PSPH,SERINC5,ENO2,CBS,HMGCS1,FIG4,CERS4,PCK2,ESD,SYK,B4GALT6,GSTM2,AGPAT4,ELOVL3,AK4,GUCY1A2,TERT,ACER2,XBP1,SRD5A3,CMPK2,CERS1,PTGES,B4GALT7 |
| 3.713e-02 | -3.29 | cell cortex region | cellular component | GO:0099738 | 34 | 7 | 18223 | 1724 |
PHLDB2,GPSM2,UNC13B,ENO1,PCLO,RIMS2,GNAI1 |
| 3.714e-02 | -3.29 | HOMER3 (homer scaffold protein 3) | protein interactions | 9454 | 53 | 10 | 17029 | 1718 |
CEBPB,DBN1,USP2,FAT1,ABI3,HOMER2,TRPC1,PKN1,HOMER3,PATJ |
| 3.714e-02 | -3.29 | PLD2 (phospholipase D2) | protein interactions | 5338 | 53 | 10 | 17029 | 1718 |
GAPDH,ALDOC,ALDOA,PRKCD,PRKCA,SKAP1,TNFRSF19,STXBP1,CHRM3,CRYL1 |
| 3.714e-02 | -3.29 | ITGB3 (integrin subunit beta 3) | protein interactions | 3690 | 53 | 10 | 17029 | 1718 |
PLA2G4A,PXN,FN1,PRKCB,MYO10,ITGB3,EPS8,VIM,SYK,PDGFRB |
| 3.714e-02 | -3.29 | TNIK (TRAF2 and NCK interacting kinase) | protein interactions | 23043 | 53 | 10 | 17029 | 1718 |
GSN,PPM1E,DISC1,TNIK,TRIM2,ANK2,RAP2A,WWC1,TIAM2,NEDD4 |
| 3.716e-02 | -3.29 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | MSigDB lists | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | 101 | 16 | 17377 | 1707 |
RPS20,RPL26,RPL12,RPL28,RPS11,DNAJC3,RPL21,IPO5,GTF2F2,RPS12,RPL4,RPL26L1,RPS23,RPL13A,RPL34,RPS13 |
| 3.716e-02 | -3.29 | AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 | MSigDB lists | AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 | 101 | 16 | 17377 | 1707 |
PDLIM7,TFCP2L1,ACSL1,CAP2,KIF5C,ITPR2,NEO1,KCNK15,ABCA5,TRPC1,LRP6,KIAA0513,TSHR,SLIT2,ZNF701,RRAGD |
| 3.720e-02 | -3.29 | V$MYCMAX_B | MSigDB lists | V$MYCMAX_B | 253 | 34 | 17377 | 1707 |
BCL11B,LRFN5,ID1,SYT12,RIMKLA,EPS8,NPM1,CEBPA,FAM117B,SEZ6L2,HPCAL4,ZNF362,PCBP4,ACVR2A,TMEM132E,GFI1,MICAL2,TMEM43,WWC1,RNF125,SNAP25,SDK1,ZDHHC14,CTIF,ENPP6,RND3,PTK7,LAMB1,C1orf21,RAI14,DBP,HS3ST3B1,NKX2-8,HOXB9 |
| 3.720e-02 | -3.29 | V$CREB_Q2 | MSigDB lists | V$CREB_Q2 | 253 | 34 | 17377 | 1707 |
PHACTR3,MRC2,CCDC148,ID1,LMCD1,CHAC1,SEZ6L2,FSTL5,CDC14B,DACT1,CACNB2,TMEM86A,EIF1,PRELID1,FBXL2,SYNGR3,ARL4D,RBMS2,DUSP1,PNRC1,NR6A1,PTPRU,BNIP3L,ATF3,PNMA6A,RNF44,MBNL2,SPATA7,HERPUD1,ZNF711,ZBTB20,GEM,PPARGC1A,ATG5 |
| 3.721e-02 | -3.29 | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP | MSigDB lists | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP | 184 | 26 | 17377 | 1707 |
EVL,UGT8,MYO10,LRP4,YPEL2,ACO1,UBAC2,CD40,CD7,KBTBD11,DDR1,TPK1,QPRT,NSD1,FKBP9,TIFA,HPSE,PIK3AP1,AKT3,C1orf53,SGK3,INPP4B,INPP5F,TBC1D9,TESC,PRKACB |
| 3.721e-02 | -3.29 | GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_UP | MSigDB lists | GSE42021_TREG_PLN_VS_TREG_PRECURSORS_THYMUS_UP | 184 | 26 | 17377 | 1707 |
EFNB2,UROS,ABCC4,RHOBTB1,GRK6,GAS6,PALLD,PLCB1,HOPX,MECOM,RAB11FIP5,GPRC5B,NACC2,PDE10A,FAT1,KAZN,C1orf21,NBEA,MYOM2,GRB10,TNFSF15,OXTR,ZNF365,TMEM120B,ATP2B1,SNAI2 |
| 3.721e-02 | -3.29 | GSE27786_BCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_BCELL_VS_NKTCELL_DN | 184 | 26 | 17377 | 1707 |
TYRO3,TTC39B,ROBO2,FGF13,CRIM1,GPR65,SLK,ARL15,EFHC2,RNF24,ATP1B1,NDFIP2,LEPR,KCTD15,SEC16B,ADCK1,SLC16A2,SLC7A5,PAM,LOXL4,HK1,NCEH1,SEMA3A,PTPRE,TNFRSF11A,SPRY2 |
| 3.721e-02 | -3.29 | GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | 184 | 26 | 17377 | 1707 |
SESN2,RUNX2,TCP11L2,CRIM1,LPCAT2,WLS,PDE8A,PRKCQ,ATF3,PLEKHA1,LACC1,SKAP1,TNFRSF19,IKZF2,IL18R1,TBC1D19,SMAD3,IKZF3,FAM168A,CDH17,MYO6,SEPT3,LIFR,MLLT3,FES,ATP2B1 |
| 3.721e-02 | -3.29 | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP | MSigDB lists | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_UP | 184 | 26 | 17377 | 1707 |
UST,PPP1R3D,RGS16,NR4A1,BCL6B,RNF24,TJP1,EPHB1,KCNC4,COL14A1,CBLN1,GRPEL2,SCIN,PLS3,RTN1,HTR7,RND2,RANBP2,KCNK15,TLR3,NCKAP1L,MAP7,CLMN,DNAH5,ZNF385A,RRAGD |
| 3.721e-02 | -3.29 | GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP | 184 | 26 | 17377 | 1707 |
MYO1D,TMEM63C,RIN2,TES,LRRK2,MAFB,VIM,COTL1,NPC2,ARRDC4,TTC30B,ATP10D,TSPAN17,STK24,EYA4,RAB11FIP5,RND3,RAI14,SREBF1,MAOA,SGK1,FAM149A,SH3PXD2B,CERS4,PTPRE,VGLL4 |
| 3.721e-02 | -3.29 | GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN | 184 | 26 | 17377 | 1707 |
DPYSL5,CDH26,ITGB7,RASAL2,GLIPR1L1,LPCAT2,ESRRG,GPR65,PPFIBP2,OTX1,AK4,WWC1,RABAC1,ATP1B1,LDHD,RPL13A,PRELID2,OSBPL5,BMP1,TRIM3,SHF,MED7,SCN2A,SLFN5,NR3C2,XKR4 |
| 3.721e-02 | -3.29 | GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24INT_VS_CD24LOW_TCONV_THYMUS_DN | 184 | 26 | 17377 | 1707 |
PTCH2,EHHADH,SCAMP1,SIDT1,BMPR2,VLDLR,PPFIBP2,OPHN1,MORC4,GATA3,LAMC3,HERC5,SPATS2L,HERC6,PALLD,DSP,GNAI1,ISG20,ID3,SLC7A11,WWTR1,TSC22D1,KIAA0513,TUFT1,ATP2B4,LAMP3 |
| 3.721e-02 | -3.29 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | 184 | 26 | 17377 | 1707 |
ITGB7,GPM6A,GAPDH,ABCC4,COL4A3,COBLL1,VIM,COTL1,CCNG1,JAM3,TYMP,ZBTB38,EEF2,TM9SF2,EHD3,ALDOA,XBP1,RGS10,RAB31,SCRN1,ZBTB20,MARCKS,SP140,TBC1D9,CKAP4,GAB2 |
| 3.721e-02 | -3.29 | GSE17721_LPS_VS_POLYIC_16H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_16H_BMDC_DN | 184 | 26 | 17377 | 1707 |
EFNB2,RIN2,MOCOS,GCNT2,PXN,MYO10,STAT4,LDLR,NFE2L1,LPIN3,SEZ6L2,CACNB4,DCBLD2,CCNJ,SEMA4F,SCN1B,EIF4EBP1,ALDH1L1,CCNA1,TSPAN13,TOX,ZFP36L2,ZNF385A,RBMS2,TBC1D8,PARP9 |
| 3.721e-02 | -3.29 | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_DN | MSigDB lists | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_DN | 184 | 26 | 17377 | 1707 |
BCL11B,CCDC126,TBKBP1,NMNAT3,MRC2,ALDH2,CLYBL,LDLR,LRMP,FERMT2,CHADL,PRKAR2B,FAM198B,SLC12A6,PHLDA2,ARHGEF26,RTN1,ID3,SPEG,SCN1B,MYC,SLCO5A1,ARL4D,NRP1,PDGFRB,GLI1 |
| 3.721e-02 | -3.29 | GSE3982_MAST_CELL_VS_TH2_UP | MSigDB lists | GSE3982_MAST_CELL_VS_TH2_UP | 184 | 26 | 17377 | 1707 |
ZNF516,MEIS2,SORBS1,DSTN,ZCCHC24,NDRG2,ZFYVE9,GNAI1,GALNT3,GALNT1,CPVL,PMEPA1,ABI3BP,FAT1,MARCH3,ZBTB20,GRB10,PCOLCE2,TPM1,NRP1,SPRY2,MID1,DOCK6,SMYD3,SMPDL3A,HEY1 |
| 3.722e-02 | -3.29 | POTEI (POTE ankyrin domain family member I) | protein interactions | 653269 | 32 | 7 | 17029 | 1718 |
CYP51A1,NDUFA4L2,PHACTR2,MYO6,CAP2,MME,DKK1 |
| 3.723e-02 | -3.29 | arsenate detoxification I (glutaredoxin) | BIOCYC pathways | HUMAN_PWY-4202 | 3 | 2 | 902 | 105 |
GSTO1,PNP |
| 3.723e-02 | -3.29 | gamma-linolenate biosynthesis II (animals) | BIOCYC pathways | META_PWY-6000 | 3 | 2 | 902 | 105 |
ACSL1,SLC27A2 |
| 3.723e-02 | -3.29 | arsenate detoxification I (glutaredoxin) | BIOCYC pathways | META_PWY-4202 | 3 | 2 | 902 | 105 |
GSTO1,PNP |
| 3.725e-02 | -3.29 | Tetraspannin | pfam domains | PF00335 | 33 | 7 | 17054 | 1666 |
CD37,TSPAN13,TSPAN12,TSPAN15,TSPAN9,TSPAN17,CD53 |
| 3.735e-02 | -3.29 | cellular response to extracellular stimulus | biological process | GO:0031668 | 232 | 31 | 17256 | 1658 |
PRKAA2,TRPM4,FADS1,GDAP1,SESN2,ATF4,BMPR2,IL15,ITGA6,LRRK2,NUAK2,CBS,MARS,ATF3,GAS6,SESN1,STK24,BAIAP2,GABARAPL1,ASNS,PMAIP1,BHLHA15,CTSV,XBP1,SREBF1,PIK3C2B,CADPS2,ATG5,ATP2B1,RRAGD,RNF152 |
| 3.735e-02 | -3.29 | GO_NEGATIVE_REGULATION_OF_GROWTH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_GROWTH | 227 | 31 | 17377 | 1707 |
SEMA6B,MSX1,BMPR2,FGF13,MSTN,DCC,APBB1,WWC1,WNT11,SAV1,SEMA6A,DCBLD2,BCL11A,SMAD3,ENPP1,PTPRJ,SEMA4F,STC2,SH3BP4,ADRB1,BCL6,BBC3,SEMA3C,BMP4,WWC2,NRP1,ENO1,SEMA3A,SLIT2,SEMA6C,TLL2 |
| 3.738e-02 | -3.29 | GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | MSigDB lists | GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | 1570 | 175 | 17377 | 1707 |
EXPH5,DOC2A,THOC5,GRIK2,SYT12,KIF5A,ATP8A1,VAMP8,NPM1,ITPR2,SYT14,SNX9,NUP62CL,TRPS1,ADPRHL1,SEC16B,PMAIP1,PPFIA2,RAP2A,RAB26,LIN7A,TMED9,CTTN,COG3,PACSIN1,MYRIP,RASGRP1,TBC1D8,GDAP1,CD55,KCNIP3,ERGIC1,WLS,ANK2,TGFA,ATOX1,LRMP,JPH1,BNIP3L,FEZ1,TRIM9,ATP7B,BBC3,TC2N,CHMP4C,PRKAA2,SEC24D,TBC1D1,STXBP6,OPHN1,GPSM2,SLC1A3,APBA1,DYNC1I1,TTC30B,PGAP1,SPIRE1,RPL13A,BNIP1,GATA2,RPS11,LRP6,BNIP3,CADPS2,LMAN2,STXBP1,RIMS2,RPS23,RPL26,TBC1D8B,MYO10,PLEKHA8,TTC30A,RYR2,STRADB,PEX5L,NPC2,SNAP25,HERPUD1,TBC1D2,VPS37D,RPL28,SH3GL2,WDR19,HK2,RAB31,DYNC2LI1,PTPRN2,FNBP1L,TESC,SFN,SIX2,CREB3L2,SCAMP1,RHOD,AKAP5,MYO1B,CANX,NRXN1,PIBF1,DENND3,PCLO,TBC1D30,ZFYVE9,SLC22A17,UNC13B,BCL6,MARCKS,PROS1,RPL26L1,RAB27B,KCNB2,RPS13,TUBA1A,TRAM1L1,SYNJ2BP,ATP1B1,RAB38,TBC1D16,SNCA,RANBP2,IFT81,ARHGAP21,KPNA3,SEPT5,STON2,THOC3,RAB30,RPS20,MYO1D,SLC6A9,ATP9A,IPO5,KIF5C,RASD1,GAS6,NDFIP2,NEDD4,MCU,RPL34,RAB11FIP5,BHLHA15,EHD3,RASD2,PRKG2,DYNC2H1,MYO6,TBC1D9,RRAS2,SPRY2,SYK,RAB3B,RAB6B,CYTH3,RPL21,MEI1,RASA3,PRICKLE1,MAP1B,HOMER3,RERE,PTPRC,RPL12,MYADM,OSBPL5,RPL4,RPS12,GEM,TBC1D4,KIF1B,CACNA2D1,ATP2B4,DDIT3,ABCG1,SNPH |
| 3.739e-02 | -3.29 | oligosaccharide metabolic process | biological process | GO:0009311 | 79 | 13 | 17256 | 1658 |
GALNT3,MAN2B2,GALNT1,B3GALT1,GALNT12,GALNT6,ST6GAL1,B3GALT2,ST6GALNAC3,GALNT17,GALNT13,GALNT18,GALNT14 |
| 3.741e-02 | -3.29 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN | 142 | 21 | 17377 | 1707 |
FADS1,MICAL2,KDM5B,CYP2J2,CYP4V2,SCD,ASPH,CYP26A1,CYP51A1,MSMO1,KMO,PLOD2,FMO4,P4HA2,PAM,SQLE,P4HA1,CYP2U1,MOXD1,CYP1B1,NOS3 |
| 3.741e-02 | -3.29 | GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP | MSigDB lists | GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP | 142 | 21 | 17377 | 1707 |
SLC3A2,GAPDH,EDA2R,CSN2,FBXO4,SLC39A8,CCNG1,SLC19A2,ZFYVE9,HECTD2,TPK1,MCU,PLS3,ISG20,LGI2,ICA1,ASNS,PMAIP1,ERRFI1,CPE,GAB2 |
| 3.741e-02 | -3.29 | RASHI_RESPONSE_TO_IONIZING_RADIATION_5 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_5 | 142 | 21 | 17377 | 1707 |
SPATA6,CYTH3,NFIA,PDE8A,COL14A1,NEDD4,TTC1,INHBC,NACC2,TDO2,CFHR1,DSG2,STC2,TFAP2A,TRIM3,GSTM3,GRB10,DAB2IP,BMPR1A,IQGAP3,PCSK5 |
| 3.752e-02 | -3.28 | Glutathione-S-Trfase_C_sf | interpro domains | IPR036282 | 40 | 8 | 18492 | 1811 |
CARS,GDAP1,GSTM2,GSTO2,GSTM4,GSTM3,GSTO1,MARS |
| 3.759e-02 | -3.28 | PETROVA_PROX1_TARGETS_DN | MSigDB lists | PETROVA_PROX1_TARGETS_DN | 62 | 11 | 17377 | 1707 |
PLA2G4A,IL32,CAP2,ARHGAP22,AHNAK2,TPM1,NRP1,CDH2,BMP6,PRKACB,GLCE |
| 3.759e-02 | -3.28 | MODY_HIPPOCAMPUS_POSTNATAL | MSigDB lists | MODY_HIPPOCAMPUS_POSTNATAL | 62 | 11 | 17377 | 1707 |
TYRO3,BDNF,KCNAB1,SH3GL2,ENO2,PRKCB,APBB1,ALDOA,RYR2,ENO1,STXBP1 |
| 3.761e-02 | -3.28 | extracellular organelle | cellular component | GO:0043230 | 2142 | 226 | 18223 | 1724 |
PLBD2,HEBP1,ATP8A1,DNAJC3,VAMP8,UGDH,ASS1,JCHAIN,NDRG2,PRKCA,SNX9,RAC3,HMCN1,AARS,STK24,QPRT,TXNDC5,TUBB4A,EPCAM,CPNE2,TGFBR3,TM9SF2,CPVL,PPFIA2,ITGB3,SERINC2,GSTM3,LIN7A,TMED9,GGACT,CPE,ENO1,SLIT2,NEB,PRKACB,ITGB7,GPM6A,CD55,SLC3A2,CEMIP2,WLS,ALDH1L2,DSTN,LRRK2,CAPN5,CR2,PRKAR2B,F12,COTL1,PLEKHA1,GNAI1,AK1,GSN,GPRC5B,NCKAP1L,ENPP6,GNB4,ALDOA,BDH2,SEMA3C,SERPINI1,DNHD1,MLLT3,CRYL1,GNG12,FN1,LGALS3,HID1,PTPRD,GABRB2,CYP2J2,SLK,PHGDH,PFN2,EFEMP1,EEF2,CA2,RPS11,LMAN2,LOXL4,SLCO4C1,STXBP1,GFRA1,CKAP4,RIMS2,RPL26,MID2,QSOX1,RHOQ,PNP,SLC27A2,FASN,PACSIN3,PDE8A,PLS1,C1R,NPC2,CDC42BPA,ARRDC4,PLCB1,SLC46A3,CLN5,BAIAP2,MAPKAPK2,VPS37D,GSTO2,RPL28,ADAMTS3,THBS4,FAT1,SH3BP4,MME,SFN,EML5,DNM3,CFH,C4A,MYO1B,COBLL1,COL18A1,CANX,DDR1,PCLO,DOCK2,TIAM2,SCIN,CD53,RIDA,PLPP1,ALDOC,ALDH1L1,MARCKS,PROS1,RPL26L1,RAB27B,GATM,HSPA2,RPS13,CTH,GCA,GAPDH,COL6A2,GARS,TUBA1A,THSD4,PTPN6,ACO1,ADCY1,VIM,GSTO1,ATP1B1,CD40,DSP,FRK,WARS,PATJ,ENTPD1,PTPRJ,PRKCB,LAMB1,PAM,PTPRS,HPGD,LIFR,CNTN1,RPS20,MAN2B2,WASF3,SERINC5,TNIK,MYO1D,ROBO2,ENO2,C1QTNF3,RUSC2,ARL15,EPS8,BLVRB,GAS6,CREB5,EPHB1,SELENOP,NEDD4,RPL34,NKX6-1,MGAT1,GPR155,PRKCD,DSG2,ACTA2,DYNC2H1,MYO6,ESD,RRAS2,SMPDL3A,ATP2B1,CES3,MOB1B,GSTM2,RAB3B,ALDH2,PTPN13,GRID1,MARS,AGAP2,RACK1,SMPDL3B,GPLD1,GALNT3,PTPRC,DDAH1,CD37,FGR,RPL12,FAT4,PLOD2,PRCP,SLC7A5,UACA,RPL4,SLC1A5,CACNA2D1,CRISPLD1,TPT1,ATP1A3,STOM |
| 3.762e-02 | -3.28 | LEI_MYB_TARGETS | MSigDB lists | LEI_MYB_TARGETS | 306 | 40 | 17377 | 1707 |
CREB3L2,FN1,GATA3,DDR1,RAC3,EPCAM,PPM1E,IDI1,ASNS,MYC,TFAP2A,ACTA2,KLF9,ZFP36L2,CYP1B1,FADS1,PNP,CRIM1,ARID5B,CRIP2,FHL2,EFNA3,LITAF,VIM,GSTO1,TMEM47,PALLD,BAIAP2,ISG20,CEBPB,MMP15,SMAD3,PLK2,LAMB1,XBP1,SLC7A5,AHNAK2,MAOA,TPM1,SFN |
| 3.770e-02 | -3.28 | Tetraspanin/Peripherin | interpro domains | IPR018499 | 33 | 7 | 18492 | 1811 |
CD37,TSPAN13,TSPAN12,TSPAN15,TSPAN9,TSPAN17,CD53 |
| 3.770e-02 | -3.28 | VG_K_chnl | interpro domains | IPR028325 | 33 | 7 | 18492 | 1811 |
KCNV1,KCND3,KCNQ3,KCNC4,KCNG1,KCNB2,KCNS3 |
| 3.771e-02 | -3.28 | positive regulation of epithelial cell proliferation | biological process | GO:0050679 | 197 | 27 | 17256 | 1658 |
VEGFC,SCN5A,ID1,KDM5B,BMPR2,NR4A1,TGFA,PRKCA,BMP6,FGFR1,F3,FOXP2,GATA2,THBS4,DLX6,APELA,AKT3,MYC,XBP1,LAMB1,ITGB3,EGFL7,BMPR1A,BMP4,VASH2,NRP1,IQGAP3 |
| 3.775e-02 | -3.28 | adenyl nucleotide binding | molecular function | GO:0030554 | 1514 | 168 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,ASS1,PRKCA,AARS,STK24,MOK,BAG3,RPS6KA2,DNAH6,CNNM2,EPHB6,PRKACB,PDGFRB,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,PIK3C2B,DNHD1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,BVES,SCN8A,SLK,RIMKLA,CHD5,GRPEL2,HSPA12B,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,MYO10,SLC27A2,RAPGEF4,OBSCN,STRADB,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,HK2,SLFN5,PANK3,ACSM3,EPHA3,NEK10,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,MET,DNAH5,HSPA2,FER,GARS,MYLK3,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,PTK7,MAP3K21,BMPR1A,MAPK10,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,NLRP14,KIF5C,P2RY1,PKN1,EPHB1,PRKCD,EHD3,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,MYO6,SYK,ATP2B1,FES,PFKFB4,TRPM4,OPLAH,RAPGEF2,NUAK2,AK4,MARS,ATP11A,PEAK1,TRIB3,FGR,AKT3,MAP2K6,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,CMPK2,MAP3K20,KIF1B,ATP2B4,ABCG1,ATP1A3 |
| 3.780e-02 | -3.28 | TYR_PHOSPHATASE_1 | prosite domains | PS00383 | 72 | 13 | 12060 | 1278 |
PTPRC,SSH3,PTPRJ,DUSP8,PTPRU,CDC14B,PTPRD,PTPN6,PTPN21,PTPRN2,PTPRS,PTPRE,DUSP1 |
| 3.793e-02 | -3.27 | Long-term depression | KEGG pathways | ko04730 | 60 | 11 | 7161 | 730 |
PLA2G4A,IGF1R,PRKCB,GNAO1,PRKG1,PRKG2,ITPR2,PRKCA,GUCY1A2,PLCB1,GNAI1 |
| 3.793e-02 | -3.27 | Long-term depression | KEGG pathways | hsa04730 | 60 | 11 | 7161 | 730 |
PLA2G4A,IGF1R,PRKCB,GNAO1,PRKG1,PRKG2,ITPR2,PRKCA,GUCY1A2,PLCB1,GNAI1 |
| 3.797e-02 | -3.27 | GBA (glucosylceramidase beta) | protein interactions | 2629 | 46 | 9 | 17029 | 1718 |
PRKN,JPH1,DHCR24,CANX,RAB27B,NEDD4,B4GALT7,PATJ,SNCA |
| 3.807e-02 | -3.27 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP | 159 | 23 | 17377 | 1707 |
BCL11B,DMXL2,RPL26,MRC2,FGF13,PLEKHA5,MGST3,COL4A5,ATP1B1,PRKCA,PLCB1,IRS2,PLAGL1,AFF2,XBP1,CCNA1,HGF,GFI1,PTPRE,SPRY2,CEBPD,ATP2B4,DUSP1 |
| 3.807e-02 | -3.27 | UEDA_PERIFERAL_CLOCK | MSigDB lists | UEDA_PERIFERAL_CLOCK | 159 | 23 | 17377 | 1707 |
USP2,TUBA1A,PNP,PNRC1,CRIP2,LITAF,SPATA13,FASN,FERMT2,COL18A1,CEBPA,HERPUD1,GABARAPL1,CEBPB,HMGCS1,IDI1,TSC22D1,BNIP3,KLF9,DHCR7,HMGCR,CES3,GLDC |
| 3.807e-02 | -3.27 | GCNP_SHH_UP_EARLY.V1_DN | MSigDB lists | GCNP_SHH_UP_EARLY.V1_DN | 159 | 23 | 17377 | 1707 |
PLA2G4A,PHLDB2,BTC,PDE1B,UROS,NR6A1,PPFIBP2,RABAC1,KIAA1217,ASPH,GPR19,JAM3,EOMES,POPDC3,PLK2,EEPD1,DBP,WWC2,HOXB9,ZNF518B,FOXA1,FRMD5,RRAGD |
| 3.810e-02 | -3.27 | VANTVEER_BREAST_CANCER_BRCA1_DN | MSigDB lists | VANTVEER_BREAST_CANCER_BRCA1_DN | 40 | 8 | 17377 | 1707 |
SYNJ2BP,CA2,ZNF395,BMPR2,SCAMP1,ITGBL1,SH3BP4,PRKG1 |
| 3.810e-02 | -3.27 | chr12q21 | MSigDB lists | chr12q21 | 40 | 8 | 17377 | 1707 |
LIN7A,SLC6A15,GLIPR1L1,OTOGL,LRRIQ1,PPFIA2,CSRP2,ATP2B1 |
| 3.810e-02 | -3.27 | ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN | MSigDB lists | ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN | 40 | 8 | 17377 | 1707 |
PGM2L1,HRK,TMOD2,SDK1,APBA2,SCN3A,GNAI1,ADCY1 |
| 3.810e-02 | -3.27 | GO_RECEPTOR_CLUSTERING | MSigDB lists | GO_RECEPTOR_CLUSTERING | 40 | 8 | 17377 | 1707 |
ITGB7,GRIK2,LRP4,WDR19,DLG2,NRXN1,CDH2,MAGI2 |
| 3.810e-02 | -3.27 | GO_STRUCTURAL_CONSTITUENT_OF_MUSCLE | MSigDB lists | GO_STRUCTURAL_CONSTITUENT_OF_MUSCLE | 40 | 8 | 17377 | 1707 |
OBSCN,MYOM2,TPM1,PDLIM3,ASPH,NEB,JPH1,SMTN |
| 3.810e-02 | -3.27 | LUI_THYROID_CANCER_CLUSTER_2 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_2 | 40 | 8 | 17377 | 1707 |
KIF5C,WWC1,EPB41L3,IPCEF1,ID1,ZCCHC24,WFS1,BNIP3L |
| 3.810e-02 | -3.27 | GO_LUNG_ALVEOLUS_DEVELOPMENT | MSigDB lists | GO_LUNG_ALVEOLUS_DEVELOPMENT | 40 | 8 | 17377 | 1707 |
FOXP2,BMP4,ERRFI1,BMPR2,FOXA1,HOPX,NKX2-1,FZD1 |
| 3.813e-02 | -3.27 | CTDSP2 (CTD small phosphatase 2) | protein interactions | 10106 | 39 | 8 | 17029 | 1718 |
EPHA3,TYRO3,ANKRD13D,PTK7,P4HA1,MAP7,INTS6,TBC1D4 |
| 3.813e-02 | -3.27 | EFNB1 (ephrin B1) | protein interactions | 1947 | 39 | 8 | 17029 | 1718 |
EPHA3,EFNB2,SORBS1,ERGIC1,PTPN13,MYC,GRIP1,EPHB1 |
| 3.816e-02 | -3.27 | CAGCCTC,MIR-485-5P | MSigDB lists | CAGCCTC,MIR-485-5P | 134 | 20 | 17377 | 1707 |
PAK1,PDLIM7,TBKBP1,ITPRIP,LRP4,DCHS1,TTYH2,IGF2BP2,CADM2,ARHGAP32,TNKS1BP1,NOVA1,GLCE,SLC16A2,ANKFN1,NBEA,PPARGC1A,PANK3,MLLT3,FZD1 |
| 3.822e-02 | -3.26 | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_DN | MSigDB lists | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_DN | 193 | 27 | 17377 | 1707 |
PHLDB2,GAPDH,CELSR1,IGFBP6,FERMT2,HBE1,IL13RA1,STAT5B,ROR1,DYNC1I1,TLR6,GAS1,F3,RAB11FIP5,ENPP1,SOAT2,MPP7,MGAT1,ENTPD7,DSG2,TMEFF2,PACSIN1,PTPRE,MYT1,TNFRSF11A,LIFR,LPP |
| 3.822e-02 | -3.26 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN | 193 | 27 | 17377 | 1707 |
ARHGAP26,SERINC5,RIN2,GARS,TES,CACNA1E,ZCCHC24,TGFA,MSR1,KCTD12,OVOL2,ITPR2,RNF44,HERPUD1,QPRT,BEX4,CHN2,CPVL,PRCP,RUNDC3B,KCNS3,SLC1A5,TPM1,SEMA3A,AMPD1,PRKACB,ABCG1 |
| 3.822e-02 | -3.26 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_UP | 193 | 27 | 17377 | 1707 |
BTC,USP2,COL6A2,SKAP2,RECK,ATP9A,PLEKHA5,SPATA6,CYTH3,RAPGEF4,PPFIBP2,WNT11,MCOLN2,RPL12,CA2,SEMA4F,RALGPS2,FUT9,AKAP7,MAP2K6,ITGB3,BCL6,MAP7,ZBTB20,MYOM2,HGF,ABCG1 |
| 3.822e-02 | -3.26 | KCHANNEL | prints domains | PR00169 | 33 | 7 | 4652 | 458 |
KCNV1,KCND3,KCNQ3,KCNC4,KCNG1,KCNB2,KCNS3 |
| 3.823e-02 | -3.26 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | MSigDB lists | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | 33 | 7 | 17377 | 1707 |
ATP1B1,ATP11A,ATP9A,ATP10D,ATP7B,ATP8A1,ATP1A3 |
| 3.823e-02 | -3.26 | GO_ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS_PHOSPHORYLATIVE_MECHANISM | MSigDB lists | GO_ATPASE_ACTIVITY_COUPLED_TO_TRANSMEMBRANE_MOVEMENT_OF_IONS_PHOSPHORYLATIVE_MECHANISM | 33 | 7 | 17377 | 1707 |
ATP6V1E2,ATP1B1,ABCC4,ATP7B,ATP2B4,ATP2B1,ATP1A3 |
| 3.823e-02 | -3.26 | TANG_SENESCENCE_TP53_TARGETS_UP | MSigDB lists | TANG_SENESCENCE_TP53_TARGETS_UP | 33 | 7 | 17377 | 1707 |
TSPAN12,HBG2,PSTPIP2,BACE1,VAMP8,RAPGEF4,SNCA |
| 3.823e-02 | -3.26 | CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP | MSigDB lists | CREIGHTON_AKT1_SIGNALING_VIA_MTOR_UP | 33 | 7 | 17377 | 1707 |
MMP15,SYNJ2BP,MVK,SLC37A1,DDR1,PRKCD,BIK |
| 3.823e-02 | -3.26 | DOANE_BREAST_CANCER_CLASSES_DN | MSigDB lists | DOANE_BREAST_CANCER_CLASSES_DN | 33 | 7 | 17377 | 1707 |
MARCH3,ATP11A,POPDC3,PMAIP1,PLOD2,WWTR1,CEBPD |
| 3.823e-02 | -3.26 | WESTON_VEGFA_TARGETS_12HR | MSigDB lists | WESTON_VEGFA_TARGETS_12HR | 33 | 7 | 17377 | 1707 |
BDNF,VIM,OXTR,GEM,CFHR1,DIRC2,IGFBP3 |
| 3.823e-02 | -3.26 | GO_NEURON_RECOGNITION | MSigDB lists | GO_NEURON_RECOGNITION | 33 | 7 | 17377 | 1707 |
EPHA3,AMIGO1,CNTN4,NRP1,ROBO2,CELSR3,SEMA3A |
| 3.823e-02 | -3.26 | GO_POSITIVE_CHEMOTAXIS | MSigDB lists | GO_POSITIVE_CHEMOTAXIS | 33 | 7 | 17377 | 1707 |
VEGFC,HGF,PTPRJ,BMP4,NRP1,LGALS3,MET |
| 3.823e-02 | -3.26 | YOKOE_CANCER_TESTIS_ANTIGENS | MSigDB lists | YOKOE_CANCER_TESTIS_ANTIGENS | 33 | 7 | 17377 | 1707 |
TUBB4A,MOK,MVK,FBXL2,WFS1,FABP6,SLC7A5 |
| 3.831e-02 | -3.26 | GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_UP | MSigDB lists | GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_UP | 176 | 25 | 17377 | 1707 |
SKAP2,ST14,BTNL9,CKAP2,MCF2L2,CAP2,VLDLR,COTL1,SNTB1,TIAM2,MGMT,FKBP11,MCOLN2,ID3,GALNT1,TIFA,NAV1,ZBTB38,IDI1,FAM168A,GRIN2D,LRRK1,SNX10,GLIS1,TESC |
| 3.831e-02 | -3.26 | GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | 176 | 25 | 17377 | 1707 |
EVL,RUNX2,TCP11L2,PNRC1,UROS,APBB1,PREX1,NFIA,CYP4V2,TTYH2,TTC22,ABAT,SLC46A3,RPL34,DYRK1B,MSC,IKZF3,TGFBR3,EEF2,KLF12,HPS1,TSC22D1,DHRS12,NIPAL2,DOCK9 |
| 3.831e-02 | -3.26 | GSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_UP | MSigDB lists | GSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_UP | 176 | 25 | 17377 | 1707 |
MSX1,EDA2R,SCAMP1,SLC27A2,GABRB2,SYT12,ESRP1,PPFIBP2,TTC30A,RNF24,SLC7A2,SAV1,NRXN1,IKZF2,AARS,CBLN1,EPCAM,FKBP9,FMO4,NBEA,SLC6A15,FIG4,TANC2,FBXL2,ATP2B1 |
| 3.831e-02 | -3.26 | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_UP | 176 | 25 | 17377 | 1707 |
ATL1,ARAP2,RASAL2,AKAP5,CD276,HOMER2,GDPD1,DHCR24,GTF2IRD1,CALCRL,ARL2,CBS,STRADB,SCD,ATP1B1,ZNF93,SLC16A2,WFS1,MYC,MAP2K6,RAP2A,STARD4,SREBF1,SAMD13,DIRC2 |
| 3.831e-02 | -3.26 | GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN | MSigDB lists | GSE32533_MIR17_KO_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_DN | 176 | 25 | 17377 | 1707 |
PHACTR3,HEBP1,KLHL4,UBASH3B,TNFSF13B,ATP6V1E2,KCTD12,COTL1,LACC1,SKAP1,C4orf19,TLR6,EPCAM,PTPRC,RNF180,ATPAF2,PTPRJ,TMEM150B,SH3BGRL2,IPCEF1,PACSIN1,DENND1C,PTPRE,CES3,HEY1 |
| 3.832e-02 | -3.26 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 160 | 23 | 17385 | 1698 |
GRIK2,IL15,PARD3B,OGDHL,COL18A1,STAT5B,SESN1,DDR1,FRK,IKZF2,BCL11A,EBF1,FGR,RPS6KA2,IKZF3,TSC22D1,TOX,FHIT,NR3C2,SYK,IL1RAP,PANK3,MEF2C |
| 3.837e-02 | -3.26 | Gastric acid secretion | KEGG pathways | ko04971 | 75 | 13 | 7161 | 730 |
MYLK3,CA2,PRKCB,ADCY1,ADCY6,ITPR2,ATP1B1,PRKCA,PLCB1,PRKACB,CHRM3,ATP1A3,GNAI1 |
| 3.837e-02 | -3.26 | Gastric acid secretion | KEGG pathways | hsa04971 | 75 | 13 | 7161 | 730 |
MYLK3,CA2,PRKCB,ADCY1,ADCY6,ITPR2,ATP1B1,PRKCA,PLCB1,PRKACB,CHRM3,ATP1A3,GNAI1 |
| 3.842e-02 | -3.26 | RODWELL_AGING_KIDNEY_UP | MSigDB lists | RODWELL_AGING_KIDNEY_UP | 432 | 54 | 17377 | 1707 |
SCN5A,KLF8,RUNX2,IL32,FN1,ZCCHC24,MSR1,FAM198B,SLC1A3,LACC1,LCP2,CANX,SEL1L3,DOCK2,RPL13A,COL27A1,CD53,RTN1,TYMP,ASNS,MGAT1,MOXD1,PTPRE,GFRA1,DLGAP1,VEGFC,SLC40A1,ANTXR2,TUBA1A,TMEM43,PTPN6,SHANK2,PREX1,NLGN4X,PRICKLE1,RNF125,C1R,VIM,KCND3,SLC46A3,SNCA,HTR7,PTPRC,RPL12,RPL28,FBN1,GNB4,RGS10,RAB31,PAM,PGM2L1,HGF,TPM1,TESC |
| 3.845e-02 | -3.26 | ACATTCC,MIR-1,MIR-206 | MSigDB lists | ACATTCC,MIR-1,MIR-206 | 280 | 37 | 17377 | 1707 |
UST,EFNB2,TRIM2,FN1,CELSR3,YPEL2,SETBP1,PSD3,SLC7A2,CREB5,GRK6,EYA4,SLC35F1,ZNF827,TGFBR3,MAP1A,FRAS1,STC2,MET,VGLL4,TSPAN9,HMGCR,BDNF,BCL7A,KCNIP3,COL4A3,RNF145,PREX1,SNAP25,CTTNBP2NL,FNDC3A,CPEB1,NAP1L5,BACH2,TMOD2,HS3ST3B1,NRP1 |
| 3.849e-02 | -3.26 | central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_IV | 55 | 10 | 17385 | 1698 |
SYCP2,KPNA3,STXBP5L,TERT,TBC1D1,SMARCD3,SNX9,GFRA1,KIAA1549,FGFR1 |
| 3.874e-02 | -3.25 | regulation of interleukin-6 production | biological process | GO:0032675 | 112 | 17 | 17256 | 1658 |
C1QTNF3,GAS6,TLR6,IL17D,MAPKAPK2,CEBPB,TLR3,NCKAP1L,XBP1,INAVA,MAPK13,HGF,AFAP1L2,ZBTB20,TNFSF4,TLR4,IL1RAP |
| 3.874e-02 | -3.25 | NK-T_cell_lymphoma | COSMIC cancer mutations | NK-T_cell_lymphoma | 229 | 31 | 17385 | 1698 |
DMXL2,PHACTR3,PTPRD,CRIM1,THSD4,LRRK2,DNAJC6,PLXNA2,WWC1,CBS,ZNF215,PRDM1,FAM198B,PLCB1,PTPRC,GRIK4,EPB41L3,NAV1,FAT4,UNC13B,GSTO2,TACC2,PRCP,SRGAP1,P4HA1,HPGD,BNIP3,DNAH5,TBC1D4,MME,CRISPLD1 |
| 3.880e-02 | -3.25 | neuroblast division | biological process | GO:0055057 | 14 | 4 | 17256 | 1658 |
NUMBL,DOCK7,FGF13,FGFR1 |
| 3.880e-02 | -3.25 | GDP metabolic process | biological process | GO:0046710 | 14 | 4 | 17256 | 1658 |
DLG2,MPP1,MAGI3,MPP2 |
| 3.880e-02 | -3.25 | neuronal stem cell division | biological process | GO:0036445 | 14 | 4 | 17256 | 1658 |
NUMBL,DOCK7,FGF13,FGFR1 |
| 3.880e-02 | -3.25 | positive regulation of DNA damage response, signal transduction by p53 class mediator | biological process | GO:0043517 | 14 | 4 | 17256 | 1658 |
RPL26,MSX1,PMAIP1,ZNF385A |
| 3.880e-02 | -3.25 | negative regulation of homotypic cell-cell adhesion | biological process | GO:0034111 | 14 | 4 | 17256 | 1658 |
ABAT,UBASH3B,PRKCD,PRKG1 |
| 3.880e-02 | -3.25 | cellular response to dopamine | biological process | GO:1903351 | 14 | 4 | 17256 | 1658 |
PRKN,ID1,ATF4,LRRK2 |
| 3.880e-02 | -3.25 | cAMP catabolic process | biological process | GO:0006198 | 14 | 4 | 17256 | 1658 |
PDE8A,PDE4D,PDE1B,PDE10A |
| 3.880e-02 | -3.25 | response to dopamine | biological process | GO:1903350 | 14 | 4 | 17256 | 1658 |
PRKN,ID1,ATF4,LRRK2 |
| 3.880e-02 | -3.25 | establishment or maintenance of actin cytoskeleton polarity | biological process | GO:0030950 | 14 | 4 | 17256 | 1658 |
RND2,RND3,RHOBTB1,RHOD |
| 3.880e-02 | -3.25 | regulation of odontogenesis of dentin-containing tooth | biological process | GO:0042487 | 14 | 4 | 17256 | 1658 |
ENAM,RUNX2,BMP4,CSF1 |
| 3.882e-02 | -3.25 | positive regulation of B cell proliferation | biological process | GO:0030890 | 41 | 8 | 17256 | 1658 |
IRS2,PTPRC,VAV3,NCKAP1L,BCL6,TNFSF13B,CD40,MEF2C |
| 3.882e-02 | -3.25 | acidic amino acid transport | biological process | GO:0015800 | 41 | 8 | 17256 | 1658 |
PPFIA4,SNAP25,SLC1A3,UNC13B,SLC7A11,APBA1,STXBP1,PPFIA2 |
| 3.884e-02 | -3.25 | GO_CHEMICAL_HOMEOSTASIS | MSigDB lists | GO_CHEMICAL_HOMEOSTASIS | 839 | 98 | 17377 | 1707 |
PLA2G4A,GRIK2,LDLR,PKP2,CEBPA,ITPR2,CACNB4,SLC9A7,SLC22A17,CNNM2,TRPC1,STEAP3,PRKACB,CD55,SESN2,KLHL3,SFXN4,ANK2,SLC39A8,ATOX1,LRRK2,JPH1,ADCY1,ACO1,PRKAR2B,ABCC2,SLC25A28,ATP1B1,RAB38,CD40,SGK2,SNCA,IRS2,SLC39A14,SFXN1,RANBP2,ENPP1,GPRC5B,PRKCB,ATP7B,WFS1,ERN1,BDH2,BBC3,OXTR,PPARGC1A,PRKAA2,LPAR2,C1QTNF3,FN1,STXBP5L,ATP6V1E2,BTBD9,P2RY1,GAS6,SFXN3,BMP6,NEO1,MCU,RAB11FIP5,CA2,SLC30A4,SOAT2,GATA2,BHLHA15,MYC,STC2,SGK3,ADCY6,LRP6,SGK1,ATP2B1,FGFR4,TRPM4,SLC40A1,DISC1,RYR2,RASA3,NPC2,CLN5,LEPR,STEAP1,HERPUD1,PTPRC,PRCP,XBP1,HK2,PTPRN2,HK1,SFN,FOXA1,DDIT3,CACNA2D1,ATP2B4,ATP1A3,ACSM3,ABCG1,TPT1 |
| 3.890e-02 | -3.25 | binding | molecular function | GO:0005488 | 14760 | 1464 | 17224 | 1680 |
ARHGAP26,THOC5,ADAL,GRIK2,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,SNX9,TENT5C,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,SMIM20,EIF4E3,KLHL23,DCC,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,ZNF788P,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,DIRAS1,INPP5F,TPM1,DNHD1,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,BBS9,FOXG1,HPCAL4,CHN1,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,TOX,CADPS2,FAM84B,ALPK1,DENND1C,MOXD1,FIGN,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FHL2,FASN,HIP1,AIG1,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,RIMKLB,GSTO2,RPL28,QPCTL,SELENOM,CLMN,LAPTM4B,HOXD13,CDH2,SHTN1,GVINP1,DOCK9,MTG1,TFCP2L1,SCAMP1,ADD2,MAPK4,GRK6,SLC19A2,TLR3,MAGEA3,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,PFKFB2,ADM2,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,APELA,LAMB1,RAB30,CGB2,CCDC148,GCAT,BACE1,PLAG1,FZD8,ESRP1,CD276,BIK,UBAC2,PSD3,CBS,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,OPLAH,RAB6B,RASA3,AK4,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,PHC1,TLL2,PHACTR3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,MGAT5B,PLS3,RND2,CPNE2,RUFY4,RPS6KA2,AADAT,ITGB3,MPPED2,JAKMIP2,ENO1,RAPGEF5,ZNF391,DBN1,KCNIP3,MARK1,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,CR2,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,NEUROG2,TC2N,ADGRL2,CACUL1,RRAGD,LONRF1,TYRO3,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZNF215,ZIC2,PFN2,FHOD3,SPIRE1,RNF180,GALNT1,NUMBL,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,MAFB,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,FBRSL1,PLD1,SEMA3A,RNF122,SMCO4,ID1,DOCK1,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,DDX60L,SEMA6A,ZNF362,IDI1,TACC2,BCL6,EEPD1,MYH15,SNAI2,IGFBP3,RPS13,INTU,CSN2,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,HGF,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,KIZ,DYRK3,NECAB2,BMPR2,PAK5,MCTP2,RASD1,PRDM8,TTC1,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,KIAA0408,SYK,ATP2B1,PCSK6,DUSP1,FOXN3,CRIP2,PRICKLE1,FERMT2,EXOG,PALLD,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,CD37,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,TRPS1,TYMP,ZFYVE28,PALD1,GLDC,ERGIC1,ACVR1C,KLHL3,WISP3,BNIP3L,EFHC1,GNAI1,SH3RF1,BMP1,MAPK13,SPRY4,NRP1,SPOCK3,SEMA6B,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,APBA1,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,CRYBG1,SREBF1,SCARF2,PRKG1,GRIP1,CPXM2,MAST4,PRR16,BOD1,PTCH2,RPL26,DISC1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,WDR19,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,COL14A1,DDR1,TIAM2,ZFYVE9,CCDC120,SPEG,ASNS,ERG28,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,ATF3,SATB2,CBY1,ATP1B1,PYGO1,ATOH1,ATP10D,C9orf116,ISG20,SNCA,PATJ,ZNF711,IKZF3,POPDC3,BEX3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,MID1,STON2,PURG,COBL,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,KIF5C,HERC5,NDFIP2,TPD52L1,INPP1,ADGRB2,GSAP,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,RMDN2,DYNC2H1,CERS4,TBC1D9,ERRFI1,SMAD6,B4GALT6,SLC40A1,VAV3,SH3BP2,PXN,ALDH2,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,UCHL3,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,LRRK1,DDIT3,LARP1,ACSL1,ACTL8,PTPN21,C20orf194,HMCN1,F3,GSDME,ADPRHL1,EPCAM,PPM1E,ABI3BP,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,CEMIP2,YAP1,COTL1,SGK2,GSN,GPRC5B,HPSE,FAM114A2,OXTR,PPARGC1A,TNFSF4,MAGI2,FRMD5,PCSK5,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,PCDHB14,FAM27E3,RNF141,EEF2,SLC30A4,ZNF354A,INAVA,LIMCH1,VSIR,RNF148,CAND2,CEBPD,SNX7,ZNF629,PCDH10,CDH26,HBG2,ATP5IF1,PODXL2,RHOQ,GSTM4,SDC3,STEAP1,HERPUD1,RIPOR2,PLAGL1,FAT1,NCR3LG1,SH3BP4,RAB31,NXPH4,FNBP1L,NKX2-8,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COBLL1,COL18A1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,ERO1B,PPFIBP1,KAZN,REEP1,FABP6,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SP140L,PRAME,ANTXR2,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,EFCC1,CD40,ZNF569,BCL11A,BATF3,CAMK2N1,MAGEA12,ZNF93,TRIM34,KPNA3,EIF4EBP1,RBPMS2,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,SLX1B,FAM117B,IGF2BP2,OVOL2,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,TESPA1,RBMS2,PNMA2,CARD6,USP2,KDM5B,CRIM1,HNF4G,SYBU,CCDC184,ASAP3,PEAK1,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,SUGT1,ICA1,EDA,RND3,CTSV,UACA,RPS12,RNF157,IL9R,NATD1,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,LSM11,DNAJC3,CADM2,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,PCDH7,EPDR1,BAG3,CDR2L,TGFBR3,PPP1R26,FBXO32,PMAIP1,DNAH6,PPFIA2,RAB26,GGACT,TSHR,ZBED9,NKX2-1,MEIS2,SMAD9,GJB2,TGFA,CAP2,WLS,MSRB3,F12,CA13,ZNF266,ALDOA,ZBTB20,CRYL1,LPP,MEF2C,CARS,LATS2,GNG12,CYP2J2,SLK,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,CACNB2,ZIC5,LOXL4,NCAM1,ZNF518B,STXBP1,GLIS1,AGL,FMNL2,GFRA1,RPS23,LRP12,CHRM3,HMGCR,ENAM,BDNF,PNP,MYO10,STAT4,MGST3,RYR2,CALCRL,SMARCD3,PLS1,C1R,TAF4B,MBNL2,CPEB1,DHX32,BEX4,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,CSRP2,BTC,NUDT10,DNM3,ZNF516,TMSB15A,GALNT12,GALNT6,FAM131C,C4A,MYO1B,BEGAIN,RGS20,PKP2,IL13RA1,LCP2,NRXN1,COLEC10,TXNRD3,GPR15,EPB41L3,RNF150,CHRNA5,KMO,CNKSR3,DACT1,COL25A1,RTKN2,PJA1,RAB27B,SYNGR3,JAKMIP3,ARL4D,DOCK8,DZANK1,SSH3,GARS,RNF145,FZD4,NKX3-2,KCNH5,NPM3,PXYLP1,RAB38,TTC28,FGFR1,METAP1D,IRS2,GYPC,ZNF697,PEMT,WWTR1,PLEKHG1,INPP4B,PAM,RCN3,P4HA1,TNFSF15,DBP,HOXB9,C2orf88,FARP1,ROBO2,EDA2R,IPO5,P2RY1,CREB5,PKN1,TSPAN17,COL27A1,NEO1,BHLHA15,MCF2L,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,GAREM1,RACK1,SNTB1,HEG1,GALNT3,PTPRC,TRIB3,ID3,GNAO1,AKT3,XBP1,OSBPL5,HK1,SHOX2,DOCK6,BTRC,DCBLD1,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,FKBP9,KCNAB1,TCAF2,EOMES,KCNN2,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,SLC3A2,ABCC4,GDPD1,PLPP2,PLEKHA1,TCERG1L,BATF,NT5DC2,PLEKHB1,RUSC1-AS1,INHBC,MAP2,P4HA2,GNB4,TECPR2,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,ZCCHC24,UBASH3B,RASL11B,SETBP1,MLC1,IL18R1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,BNIP3,FBXL2,PAK1,CHSY3,FGFR4,MID2,SLC27A2,RNF170,HOMER2,TCEA3,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,HEYL,PANK3,TESC,SIX2,SFN,MME,PRKN,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,ZNF83,RNF24,PCLO,CBLN1,CTNNA2,CYP26A1,FAM131B,TBC1D19,RIDA,LHX6,ZDHHC6,MYO3B,ADGRL1,CLVS2,ZNF488,GLI1,CTH,EVL,TMEM67,TUBA1A,UROS,NOP53,FGF12,GSTO1,RARRES2,PAGE5,FRK,ETNPPL,JAM3,C4BPB,SMAD3,RANBP2,NRG3,GBP1,PTK7,ABI3,ITGA2,SEPT5,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SELL,HBE1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,RASD2,EIF1,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,MOB1B,DLGAP1,MICAL2,PPP1R3D,NUGGC,LITAF,NUAK2,FNDC3A,NPDC1,MAP10,MKX,TMEM237,FAT4,L3MBTL4,FMO4,ZNF214,ZNF474,ZNF808,DLG2,MYRF,RPL4,PAX9,THAP10,TBC1D4,CGN,MYCBP2,ACVR1,PPP4R4,PAGE1,SIDT1,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,RAC3,DACH2,AARS,STK24,NCS1,MOK,SLC22A18,FAM168A,CFHR1,ATRNL1,GSTM3,SP140,PACSIN1,MAGEA6,RCAN3,PLTP,TBC1D8,DCDC1,EML6,NR6A1,KLHL4,DNAJC6,DEPTOR,DESI1,MEF2B,AGO4,TNS1,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,HLF,NCKAP1L,CCBE1,PLK2,RASGRF2,ENTPD7,CCDC181,SEMA3C,UNC5B,SPART,LZTS1,ZBED8,EFNB2,INPPL1,ALOX5AP,CELSR1,EHHADH,ZHX3,PTPRD,GABRB2,SCN8A,OPHN1,GTF2IRD1,ISYNA1,SLC1A3,TNFRSF10C,DYNC1I1,ADSSL1,CHD5,RPL13A,PRRG4,MECOM,GBGT1,PDZD7,PIK3AP1,MSMO1,PRELID1,RUNDC3B,SLC16A9,TSPAN12,MPDZ,RIMS2,RNF152,EPB41L5,TBC1D8B,PLEKHA8,TCF24,COLGALT2,TTC30A,TTYH2,RABAC1,C4orf19,PLCB1,FAM162A,ZNF558,DAGLA,PMEPA1,PKN3,IQSEC2,AMPD1,ACSM3,PLA2G4A,EPHA3,TBKBP1,AMOTL1,PCSK1N,RASAL2,ELOVL4,RNF144A,ZNF311,OTX1,KCTD12,CHUK,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TENT5A,STARD4,NBEA,SCRN1,DAB2IP,MARCKS,SERPINH1,PDK1,TMEM43,SOX21,PNMA6A,PRKCQ,TBC1D16,DCBLD2,HTR7,ZNF396,PRKCB,ASIC1,MAP3K21,KLF5,GRB10,ATG5,MAPK10,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,MXI1,ATP9A,CLBA1,ARL2,RGS7,SELENOP,GDPD5,NEDD4,HOPX,KDM7A,RGS17,FTCDNL1,SOAT2,MGAT1,SGK3,RALGAPA2,PRKG2,PHYKPL,FIG4,YBX3,SEPT3,GFI1,SPRY2,SMPDL3A,PFKFB4,SYNPO2,ARAP2,HYKK,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,ZNF714,SKAP1,ZIC1,CEBPB,FGR,CLDN12,PCGF2,PGM2L1,TUFT1,GRIN2D,MYOM2,B4GALT7,OCLN,ATP1A3,NUDT17,EXPH5,MPZL3,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,JCHAIN,ABAT,CACNB4,RBM11,DNER,IKZF2,KREMEN1,QPRT,FKBP11,CYP51A1,ARHGEF10L,RTN1,TUBB4A,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,PCOLCE2,EPHB6,PTPRE,GALNT18,FANK1,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,ZNF565,ROR1,RNF44,SERGEF,GRK3,EML1,AK1,NCAM2,NCOA7,C8orf88,APBA2,BCL11B,FN1,SEC24D,JDP2,RIMKLA,ELOVL7,YPEL2,CYP4V2,ATP6V1E2,GALNT13,SATB1,PHGDH,ADGRG6,DDIT4,CA2,RPS11,EBF4,MORN4,BARX1,NOS3,RAX,MSTN,SH2D2A,PARD3B,EDEM3,WWC1,DUSP9,GALNT17,PRDM1,LHPP,AMDHD1,ADGRB3,FCHO2,RAI14,HK2,EGFL7,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,TDRKH,BCL6B,LACC1,UBTD2,DOCK2,SP8,ZSCAN5A,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,WWC2,POU2F2,MET,ZNF460,HSPA2,DPP10,GCA,PHLDB2,FER,TES,SYNJ2BP,DOCK5,TTLL7,C1orf174,WARS,TPK1,MSC,LMLN,BACH2,FAAP20,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,TNIK,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,EHD3,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,OGDHL,PRRG1,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,NACC2,GCSAM,MPP7,CT55,PRCP,MAP2K6,SLC7A5,KIF21A,GEM,MAP3K20,MMP16,STOM,SNPH |
| 3.894e-02 | -3.25 | PRKX (protein kinase, X-linked) | protein interactions | 5613 | 8 | 3 | 17029 | 1718 |
PRKAR2B,NEDD4,PKIA |
| 3.894e-02 | -3.25 | Setd2 (SET domain containing 2) | protein interactions | 235626 | 8 | 3 | 17029 | 1718 |
OBSCN,PACSIN1,LPIN3 |
| 3.894e-02 | -3.25 | GXYLT1 (glucoside xylosyltransferase 1) | protein interactions | 283464 | 8 | 3 | 17029 | 1718 |
VIM,CANX,FKBP14 |
| 3.894e-02 | -3.25 | DCDC1 (doublecortin domain containing 1) | protein interactions | 341019 | 8 | 3 | 17029 | 1718 |
TUBA1A,DYNC1I1,GAN |
| 3.894e-02 | -3.25 | GSTM5 (glutathione S-transferase mu 5) | protein interactions | 2949 | 8 | 3 | 17029 | 1718 |
GSTM3,GSTM2,GSTM4 |
| 3.894e-02 | -3.25 | Ptpn13 (protein tyrosine phosphatase, non-receptor type 13) | protein interactions | 19249 | 8 | 3 | 17029 | 1718 |
TTC1,PDE4D,FNDC3A |
| 3.894e-02 | -3.25 | Dok1 (docking protein 1) | protein interactions | 13448 | 8 | 3 | 17029 | 1718 |
SMAD3,ACVR2A,ACVR2B |
| 3.894e-02 | -3.25 | OBP2A (odorant binding protein 2A) | protein interactions | 29991 | 8 | 3 | 17029 | 1718 |
COL6A2,MOXD1,CLN5 |
| 3.894e-02 | -3.25 | CCDC186 (coiled-coil domain containing 186) | protein interactions | 55088 | 8 | 3 | 17029 | 1718 |
BAG3,RAB27B,PLEKHA5 |
| 3.894e-02 | -3.25 | GRID1 (glutamate ionotropic receptor delta type subunit 1) | protein interactions | 2894 | 8 | 3 | 17029 | 1718 |
DLG2,TCTN2,EML1 |
| 3.894e-02 | -3.25 | ZNF136 (zinc finger protein 136) | protein interactions | 7695 | 8 | 3 | 17029 | 1718 |
EFEMP1,NELL2,PPP2R2B |
| 3.894e-02 | -3.25 | SPIRE1 (spire type actin nucleation factor 1) | protein interactions | 56907 | 8 | 3 | 17029 | 1718 |
BCL7A,CBY1,SFN |
| 3.894e-02 | -3.25 | GCM_DLG1 | MSigDB lists | GCM_DLG1 | 70 | 12 | 17377 | 1707 |
EPB41L3,ARHGAP21,GPRC5B,RAPGEF2,IPO5,ZNF565,PRRG1,PLEKHA1,MAPK10,ABHD6,NCS1,PLEKHB1 |
| 3.897e-02 | -3.24 | ERLIN2 (ER lipid raft associated 2) | protein interactions | 11160 | 99 | 16 | 17029 | 1718 |
TMEM67,TUBA1A,FN1,RNF170,UBAC2,EDEM3,AMIGO1,CANX,MCU,INSIG1,EEF2,SREBF1,FKBP14,CACNA2D1,STOM,HMGCR |
| 3.897e-02 | -3.24 | Flnb (filamin, beta) | protein interactions | 286940 | 99 | 16 | 17029 | 1718 |
DBN1,ARHGAP21,ABLIM1,FARP1,TMEM237,FCHO2,PPFIBP1,DSG2,MYO1B,RAI14,PACSIN3,SVIL,CTTN,RRAS2,COBL,HACE1 |
| 3.898e-02 | -3.24 | human chr10q25.3 | chromosome location | human chr10q25.3 | 34 | 6 | 26185 | 1967 |
ATRNL1,AFAP1L2,ABLIM1,GFRA1,SHTN1,ADRB1 |
| 3.902e-02 | -3.24 | calcium ion transmembrane import into cytosol | biological process | GO:0097553 | 56 | 10 | 17256 | 1658 |
RYR2,RASA3,PTPRC,GRIN2D,ITPR2,FAM155B,FAM155A,DDIT3,ATP2B4,CACNA2D1 |
| 3.912e-02 | -3.24 | Rab-GTPase_TBC_sf | interpro domains | IPR035969 | 55 | 10 | 18492 | 1811 |
TBC1D8B,TBC1D1,TBC1D32,TBC1D9,TBC1D4,TBC1D16,TBC1D30,TBC1D2,TBC1D19,TBC1D8 |
| 3.919e-02 | -3.24 | SMAD4 (SMAD family member 4) | protein interactions | 4089 | 239 | 33 | 17029 | 1718 |
THOC5,FN1,RHOD,HERC5,CEBPA,FOXG1,MECOM,SKI,TM9SF2,GATA2,ALDOC,RASD2,ZNF521,FAM84B,RRAS2,SMAD6,CEBPD,GLI1,PAK1,RAB3B,SMAD9,NKX3-2,FHL2,NUAK2,NFIA,RAB38,SMAD3,CEBPB,RPL28,MAPK13,KLF5,OCLN,BTRC |
| 3.932e-02 | -3.24 | V$CEBPDELTA_Q6 | MSigDB lists | V$CEBPDELTA_Q6 | 228 | 31 | 17377 | 1707 |
NDUFA4L2,PLA2G4A,BDNF,PDE1B,NR4A1,GABRB2,PRDM8,ATF3,CREB5,SDK1,DOCK3,TNKS1BP1,IKZF2,MBNL2,ZFYVE9,NEDD4,NEO1,WARS,FOXP2,EFEMP1,NSD1,SLC7A11,ITGBL1,LHX6,STC2,KCNS3,MARCKS,HOXB9,SEMA3A,MID1,C15orf41 |
| 3.937e-02 | -3.23 | Small_GTP-bd_dom | interpro domains | IPR005225 | 160 | 23 | 18492 | 1811 |
RAB3B,RHOQ,RHOD,RAB6B,LRRK2,ARL2,RASL11B,RASD1,RAB38,RAC3,RND2,EEF2,RND3,RAP2A,RASD2,RAB31,RAB26,DIRAS1,GEM,RAB27B,ARL4D,RRAS2,RAB30 |
| 3.940e-02 | -3.23 | GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | MSigDB lists | GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | 168 | 24 | 17377 | 1707 |
COL6A2,CACNA1E,GABRB2,MCF2L2,APBB1,OPHN1,SSX1,HERC5,ACVR2B,GRK6,DYNC1I1,NOVA1,CHD5,DCBLD2,INHBC,POU5F1B,TERT,B3GALT2,SLC6A15,NAP1L3,CYP2U1,DENND1C,SLC43A1,ULBP1 |
| 3.940e-02 | -3.23 | GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN | 168 | 24 | 17377 | 1707 |
TRDMT1,MTG1,PRSS16,AASS,PRDM13,C3orf52,RAPGEF4,ELMOD1,HBE1,NUDT12,NOVA1,KBTBD11,MKX,AHRR,CXCL10,TMEM237,TDO2,ENTPD7,SRD5A3,TMEM143,RAB31,LIN7A,MYH15,PIP5KL1 |
| 3.941e-02 | -3.23 | GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_UP | 185 | 26 | 17377 | 1707 |
PDLIM7,PHLDB2,ATF4,WDR17,CRIM1,ITGA6,VLDLR,PPFIBP2,ARL2,GTF2IRD1,TJP1,GPSM2,LCP2,RADIL,PCLO,ISG20,EPB41L3,FKBP9,ICA1,TMEM237,ALDOC,FAM114A2,PRKG1,GSTM3,MAOA,KLF9 |
| 3.941e-02 | -3.23 | GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_UP | 185 | 26 | 17377 | 1707 |
TMC7,RHOD,MYO1B,ATF7IP2,FAM102B,C20orf194,SLITRK5,IGF2BP2,SCD,ATP1B1,ATP11A,NUDT12,STK24,TRIB3,NUMBL,CPVL,SLC30A4,SLC16A2,P4HA2,CECR2,TUFT1,SH3BGRL2,GLIS1,THSD1,TC2N,PGBD5 |
| 3.941e-02 | -3.23 | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | 185 | 26 | 17377 | 1707 |
RIN2,RHOBTB1,GALNT6,LDLR,MAFB,HERC5,PHACTR2,SPATS2L,HERC6,DDX60L,KIAA1958,ARHGAP21,SIPA1L2,HPSE,PIK3AP1,EMILIN2,NCOA7,KIAA0513,MARCKS,CTTN,FMNL2,CKAP4,TBC1D8,PARP9,LAMP3,LPP |
| 3.941e-02 | -3.23 | GSE8835_HEALTHY_VS_CLL_CD4_TCELL_UP | MSigDB lists | GSE8835_HEALTHY_VS_CLL_CD4_TCELL_UP | 185 | 26 | 17377 | 1707 |
TNK2,ITGB7,USP2,LANCL3,IL15,FBXO4,SPATA13,ADSSL1,EYA4,TRIB3,ID3,GBGT1,PMEPA1,MAP2,ABCA5,UACA,CPXM2,PRICKLE2,EGFL7,MED7,CMPK2,ETV1,STXBP1,PGBD5,NUDT17,IGFBP3 |
| 3.941e-02 | -3.23 | GSE3039_NKT_CELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_NKT_CELL_VS_B2_BCELL_DN | 185 | 26 | 17377 | 1707 |
SCN5A,SORBS1,LGALS3,PNRC1,TES,CREB5,GPR19,FKBP11,F3,SKI,CEBPB,IRS2,ATXN7L1,TRIB3,SYCP2,TECPR1,PMEPA1,CSF1,ALDOC,ALDOA,EMILIN2,XBP1,UACA,SH3PXD2B,MED7,DDIT3 |
| 3.941e-02 | -3.23 | GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP | MSigDB lists | GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP | 185 | 26 | 17377 | 1707 |
UST,BCL11B,CARD6,ALDH2,GALNT6,ATP8A1,SPATA6,ITGA6,SLC25A27,CALCRL,FAM102B,RNF24,ATP1B1,CD7,SESN1,SATB1,ATP10D,CA2,RALGPS2,IGIP,RUNDC3B,SGK1,RCAN3,RRAS2,ZFP36L2,RPS23 |
| 3.941e-02 | -3.23 | GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_DN | 185 | 26 | 17377 | 1707 |
FADS1,VEGFC,ALDH2,SLC6A9,PTPN6,MYO1B,PTPN21,TMEM126A,ATOX1,TNFSF13B,PSD3,C1R,SHISA2,CHAC1,MFSD6,FRK,TBC1D19,CD37,PRKCB,MAP2K6,COL19A1,SERPINI1,ETV1,KIF1B,GAB2,CYP1B1 |
| 3.941e-02 | -3.23 | GSE36009_UNSTIM_VS_LPS_STIM_DC_UP | MSigDB lists | GSE36009_UNSTIM_VS_LPS_STIM_DC_UP | 185 | 26 | 17377 | 1707 |
PAK1,MTG1,PPP1R3D,CARD6,GCNT2,PNP,NUAK2,DUSP9,ATF3,CHSY1,TAF4B,IKZF2,BATF3,CCNJ,F3,DEXI,FOXP2,RNF217,TRIM34,PMEPA1,RAI14,OPN3,TNFRSF1A,LAPTM4B,VGLL4,ZNF365 |
| 3.941e-02 | -3.23 | GO_DEVELOPMENTAL_MATURATION | MSigDB lists | GO_DEVELOPMENTAL_MATURATION | 185 | 26 | 17377 | 1707 |
TFCP2L1,RUNX2,IL15,RECK,DCHS1,NFIA,ZDHHC15,GATA3,CEBPA,RAB38,NRXN1,CLN5,SPINK5,FGFR1,RERE,NKX6-1,RPS6KA2,FAT4,GATA2,BHLHA15,LHX6,XBP1,POU2F2,STXBP1,FOXA1,DDIT3 |
| 3.941e-02 | -3.23 | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B2_BCELL_DN | 185 | 26 | 17377 | 1707 |
FARP1,ENO2,GDPD1,ARID5B,WWC1,SLC7A2,CREB5,HERC6,SPIRE1,BAIAP2,TBC1D19,F3,RAB11FIP5,RNF180,IFT81,IDI1,PIK3AP1,SLC7A5,GSTM3,SQLE,UACA,DBP,TANC2,ESD,NPHP1,CSRP2 |
| 3.941e-02 | -3.23 | GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_DN | MSigDB lists | GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_DN | 185 | 26 | 17377 | 1707 |
MN1,LPAR2,BTNL9,DNAJC6,GPSM1,WDFY4,INTS6,SATB1,KBTBD11,TEX9,PEAK1,CRYBG3,C9orf116,CDS1,CD53,SLC7A1,EBF1,BACH2,PRKCB,PIK3AP1,TACC2,MCC,COL19A1,IPCEF1,ST8SIA1,CTNND2 |
| 3.941e-02 | -3.23 | GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_DN | MSigDB lists | GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_DN | 185 | 26 | 17377 | 1707 |
CXCR5,PXN,ZNF565,UBAC2,CR2,CD7,SLC46A3,HEG1,BCL11A,PTPRC,EBF1,NSD1,IKZF3,RASGRF2,ADRB1,CDH17,PRICKLE2,SLCO5A1,HPGD,FBRSL1,INPP5F,TNFRSF17,SLC45A3,TESC,CTNND2,RAB30 |
| 3.941e-02 | -3.23 | GSE3039_B2_VS_B1_BCELL_DN | MSigDB lists | GSE3039_B2_VS_B1_BCELL_DN | 185 | 26 | 17377 | 1707 |
ANKRD13B,SMAD9,LGALS3,ZHX3,GSTM4,IGF2BP2,COTL1,BEX2,HOPX,GPR150,SCIN,SKI,HOMER3,SLC39A14,ICA1,TMEM237,TACC2,PTK7,MCF2L,ALDOA,OPN3,SH3PXD2B,IQGAP3,SLC1A5,RAPGEF5,CKAP4 |
| 3.941e-02 | -3.23 | GSE2585_CTEC_VS_MTEC_THYMUS_DN | MSigDB lists | GSE2585_CTEC_VS_MTEC_THYMUS_DN | 185 | 26 | 17377 | 1707 |
DMXL2,RHOQ,EIF4E3,REL,DSTN,PTPN6,AK4,PRKAR2B,SLC7A2,CD40,HERC6,ARRDC4,FAM162A,F3,DDIT4,AHRR,MAPKAPK2,CAMK2N1,CA2,CFHR1,SH3BP4,BMP1,PDE4D,PTGES,FKBP14,CAND2 |
| 3.941e-02 | -3.23 | Dopaminergic synapse | KEGG pathways | hsa04728 | 130 | 20 | 7161 | 730 |
CREB3L2,GNG12,ATF4,KIF5A,KIF5C,CREB5,ITPR2,PRKCA,PLCB1,PPP2R3A,GNAI1,PRKCB,AKT3,GNAO1,GNB4,MAOA,MAPK13,PPP2R2B,MAPK10,PRKACB |
| 3.941e-02 | -3.23 | Dopaminergic synapse | KEGG pathways | ko04728 | 130 | 20 | 7161 | 730 |
CREB3L2,GNG12,ATF4,KIF5A,KIF5C,CREB5,ITPR2,PRKCA,PLCB1,PPP2R3A,GNAI1,PRKCB,AKT3,GNAO1,GNB4,MAOA,MAPK13,PPP2R2B,MAPK10,PRKACB |
| 3.943e-02 | -3.23 | GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS | 118 | 18 | 17377 | 1707 |
NBL1,GATA3,RASL11B,NEDD4,MECOM,SKI,DKK1,SMAD3,TGFBR3,FBN1,PMEPA1,CHRDL1,DAB2IP,SMAD6,SPRY2,SLIT2,NKX2-1,FZD1 |
| 3.943e-02 | -3.23 | GO_POSITIVE_REGULATION_OF_CHEMOTAXIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CHEMOTAXIS | 118 | 18 | 17377 | 1707 |
VEGFC,FN1,BMPR2,NTRK3,RARRES2,GAS6,FGFR1,F3,SMAD3,CXCL10,NCKAP1L,THBS4,CSF1,ITGA2,MET,NRP1,SLIT2,PDGFRB |
| 3.943e-02 | -3.23 | V$GRE_C | MSigDB lists | V$GRE_C | 118 | 18 | 17377 | 1707 |
BDNF,JPH1,OTX1,PRDM1,SLC7A2,FGF17,MBNL2,IKZF2,NSD1,KCTD15,FRY,LHX6,SEMA3A,RIMS2,MEF2C,RRAGD,GAB2,ATP1A3 |
| 3.949e-02 | -3.23 | RasGEF_N | pfam domains | PF00618 | 20 | 5 | 17054 | 1666 |
RAPGEF5,RAPGEF2,RASGRF2,RASGRP1,RAPGEF4 |
| 3.949e-02 | -3.23 | TIR | pfam domains | PF01582 | 20 | 5 | 17054 | 1666 |
TLR3,TLR6,TLR4,IL18R1,IL1RAP |
| 3.953e-02 | -3.23 | entry into cell of other organism involved in symbiotic interaction | biological process | GO:0051806 | 104 | 16 | 17256 | 1658 |
EFNB2,GPR15,TYRO3,ITGB7,CD55,KPNA3,LDLR,VAMP8,ITGA2,ITGB3,CR2,GAS6,NCAM1,SLC1A5,MET,LAMP3 |
| 3.953e-02 | -3.23 | entry into host cell | biological process | GO:0030260 | 104 | 16 | 17256 | 1658 |
EFNB2,GPR15,TYRO3,ITGB7,CD55,KPNA3,LDLR,VAMP8,ITGA2,ITGB3,CR2,GAS6,NCAM1,SLC1A5,MET,LAMP3 |
| 3.953e-02 | -3.23 | entry into other organism involved in symbiotic interaction | biological process | GO:0051828 | 104 | 16 | 17256 | 1658 |
EFNB2,GPR15,TYRO3,ITGB7,CD55,KPNA3,LDLR,VAMP8,ITGA2,ITGB3,CR2,GAS6,NCAM1,SLC1A5,MET,LAMP3 |
| 3.953e-02 | -3.23 | entry into host | biological process | GO:0044409 | 104 | 16 | 17256 | 1658 |
EFNB2,GPR15,TYRO3,ITGB7,CD55,KPNA3,LDLR,VAMP8,ITGA2,ITGB3,CR2,GAS6,NCAM1,SLC1A5,MET,LAMP3 |
| 3.955e-02 | -3.23 | O-linked glycosylation of mucins | REACTOME pathways | R-HSA-913709 | 65 | 11 | 10287 | 971 |
GALNT3,GALNT1,GALNT6,GALNT12,ST6GAL1,GALNT17,GALNT13,ST6GALNAC3,GALNT14,GALNT18,B4GALT6 |
| 3.961e-02 | -3.23 | magnesium ion binding | molecular function | GO:0000287 | 195 | 27 | 17224 | 1680 |
DYRK3,MARK1,ENO2,CLYBL,ATP9A,ATP8A1,NUAK2,CDC42BPA,LHPP,ATP11A,ATP10D,NCS1,SNCA,GNAI1,ADPRHL1,PRTFDC1,RPS6KA2,RAP2A,ERN1,GEM,MAST4,ENO1,MAP3K20,TESC,PSPH,PRKACB,MAST1 |
| 3.963e-02 | -3.23 | GO_SECRETORY_VESICLE | MSigDB lists | GO_SECRETORY_VESICLE | 451 | 56 | 17377 | 1707 |
DOC2A,PLA2G4A,DMXL2,SV2B,PCSK1N,STXBP5L,SCAMP1,FN1,GLIPR1L1,SYT12,ATP8A1,VAMP8,ATP6V1E2,GAS6,APBA1,SPINK5,NCS1,PCDH7,RAB11FIP5,RND2,ITGB3,RAB26,PROS1,SYNGR3,RAB27B,STXBP1,MYRIP,CPE,CKAP4,LAMP3,VEGFC,QSOX1,DISC1,SLC40A1,GARS,RAB3B,ABCC4,LRRK2,PHACTR2,RABAC1,RARRES2,FNDC3A,BAIAP2,SNCA,TRIM9,ICA1,ALDOA,PAM,PTPRN2,HGF,SEPT5,APBA2,CTTNBP2,STON2,MME,PCSK5 |
| 3.969e-02 | -3.23 | lateral plasma membrane | cellular component | GO:0016328 | 57 | 10 | 18223 | 1724 |
EPCAM,SCN5A,FGF13,BVES,CLDN12,DSG2,ARL2,GPSM2,IQGAP3,OCLN |
| 3.969e-02 | -3.23 | human chr1q25.3 | chromosome location | human chr1q25.3 | 43 | 7 | 26185 | 1967 |
COLGALT2,RGS16,KIAA1614,CACNA1E,C1orf21,OVAAL,EDEM3 |
| 3.971e-02 | -3.23 | negative regulation of osteoclast differentiation | biological process | GO:0045671 | 27 | 6 | 17256 | 1658 |
LILRB1,MAFB,TLR3,TLR4,FBN1,UBASH3B |
| 3.971e-02 | -3.23 | isoprenoid biosynthetic process | biological process | GO:0008299 | 27 | 6 | 17256 | 1658 |
IDI1,MVK,HMGCS1,MVD,SRD5A3,HMGCR |
| 3.971e-02 | -3.23 | cranial nerve morphogenesis | biological process | GO:0021602 | 27 | 6 | 17256 | 1658 |
MAFB,NRP1,EPHB1,SEMA3A,HOXA1,TFAP2A |
| 3.971e-02 | -3.23 | regulation of microtubule depolymerization | biological process | GO:0031114 | 27 | 6 | 17256 | 1658 |
HDGFL3,FGF13,MAP1A,CKAP2,MID1,MAP1B |
| 3.978e-02 | -3.22 | GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | 78 | 13 | 17377 | 1707 |
IRS2,LGALS3,RAPGEF2,ST6GAL1,PRELID1,BCL6,LILRB1,BBC3,PRKCQ,BMP4,GAS6,DOCK8,MEF2C |
| 3.981e-02 | -3.22 | CORDENONSI_YAP_CONSERVED_SIGNATURE | MSigDB lists | CORDENONSI_YAP_CONSERVED_SIGNATURE | 55 | 10 | 17377 | 1707 |
DDAH1,COL4A3,CRIM1,SGK1,TNS1,MARCKS,GAS6,PHGDH,SLIT2,DUSP1 |
| 3.981e-02 | -3.22 | GO_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | MSigDB lists | GO_REGULATION_OF_POSTSYNAPTIC_MEMBRANE_POTENTIAL | 55 | 10 | 17377 | 1707 |
SCN5A,SCN1B,GRIK2,SCN8A,LRRK2,SCN2A,PPP1R9A,SCN3A,MEF2C,SNCA |
| 3.981e-02 | -3.22 | GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | MSigDB lists | GO_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 55 | 10 | 17377 | 1707 |
EPB41L5,MSX1,TGFBR3,EOMES,HEYL,LRP6,WNT11,HGF,SNAI2,HEY1 |
| 3.988e-02 | -3.22 | - | gene3d domains | 1.20.80.10 | 51 | 10 | 8148 | 867 |
FRMPD3,EPB41L5,EPB41L3,PLEKHH2,FARP1,MYO10,PTPN13,PTPN21,TLN2,FRMD5 |
| 3.989e-02 | -3.22 | cognition | biological process | GO:0050890 | 278 | 36 | 17256 | 1658 |
PRKN,PDE1B,FGF13,PAK5,ATP8A1,LDLR,BTBD9,NRXN1,FOXP2,KCNAB1,MAP1A,BCHE,AFF2,GPR155,SGK1,GATM,ZNF385A,HMGCR,BDNF,MEIS2,VLDLR,SHANK2,ADCY1,NLGN4X,PRKAR2B,SNAP25,PLCB1,HOXA1,DKK1,CEBPB,ADGRB3,PLK2,ASIC1,TMOD2,OXTR,MEF2C |
| 3.990e-02 | -3.22 | LI_INDUCED_T_TO_NATURAL_KILLER_DN | MSigDB lists | LI_INDUCED_T_TO_NATURAL_KILLER_DN | 110 | 17 | 17377 | 1707 |
BCL11B,BCL7A,ALDH2,PDK1,ST6GAL1,ITPR2,ACVR2B,SATB1,NAV1,PRKCB,RPS6KL1,PRKCD,ACTA2,MARCKS,GFI1,CRYL1,GLDC |
| 3.990e-02 | -3.22 | positive regulation of stem cell proliferation | biological process | GO:2000648 | 34 | 7 | 17256 | 1658 |
VEGFC,EPCAM,PTPRC,SMARCD3,DISC1,TERT,FOXG1 |
| 3.990e-02 | -3.22 | heart trabecula morphogenesis | biological process | GO:0061384 | 34 | 7 | 17256 | 1658 |
OVOL2,BMPR1A,TGFBR3,ADGRG6,HEG1,HEY1,FHL2 |
| 3.995e-02 | -3.22 | GSE12839_CTRL_VS_IL12_TREATED_PBMC_UP | MSigDB lists | GSE12839_CTRL_VS_IL12_TREATED_PBMC_UP | 143 | 21 | 17377 | 1707 |
SLC3A2,GAPDH,ERGIC1,CSN2,TSPAN15,CRIP2,PANK1,NFE2L1,COBLL1,SAV1,TPD52L1,SPATA7,LGI2,KCNJ4,ASNS,MFSD2A,UNC5B,ERRFI1,CPE,PERP,GAB2 |
| 3.995e-02 | -3.22 | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_DN | 143 | 21 | 17377 | 1707 |
VAV3,RNF144A,PTPRD,UBASH3B,PREX1,SETBP1,PSD3,CBS,FAM102B,VIM,NTRK3,SLC1A3,PPP1R9A,RTN1,IRS2,GPRC5B,GRHL1,RTKN2,GFI1,ZFP36L2,SLIT2 |
| 3.995e-02 | -3.22 | Glycine, serine and threonine metabolism | KEGG pathways | ko00260 | 39 | 8 | 7161 | 730 |
GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH |
| 3.995e-02 | -3.22 | Glycine, serine and threonine metabolism | KEGG pathways | hsa00260 | 39 | 8 | 7161 | 730 |
MAOA,CBS,PHGDH,GCAT,GATM,PSPH,CTH,GLDC |
| 3.997e-02 | -3.22 | cellular lipid metabolic process | biological process | GO:0044255 | 984 | 111 | 17256 | 1658 |
PLA2G4A,BTC,MVK,ACSL1,UGT8,ELOVL4,LPCAT2,STAT5B,LPIN3,ABHD6,ABHD4,CYP26A1,CDS1,PLPP1,IDI1,ERG28,FAAH2,FABP6,TMEM86A,SERINC2,MET,PDGFRB,ALG10B,NKX2-1,CYP1B1,SESN2,B3GALT1,MVD,GDPD1,PLPP2,HACD1,PRKAR2B,FGF17,PLEKHA1,RARRES2,ETNPPL,GPC6,FGFR1,SNCA,IRS2,INSIG1,ENPP6,PEMT,INPP4B,BDH2,TNFRSF1A,B3GALT2,PAM,HPGD,ALG11,HGF,INPP5F,PIK3C2B,CYP2U1,PPARGC1A,MBOAT2,CRYL1,PRKAA2,SERINC5,INPPL1,ALOX5AP,EHHADH,CYP2J2,OLAH,ELOVL7,CYP4V2,SCD,ISYNA1,INPP1,PGAP1,GBGT1,HMGCS1,SOAT2,PIK3AP1,MSMO1,GHR,FIG4,ST8SIA1,CERS4,PCK2,SMPDL3A,HMGCR,B4GALT6,FGFR4,FADS1,GSTM2,PLEKHA8,SLC27A2,PTPN13,AGPAT4,ELOVL3,FASN,SDC3,ST6GALNAC3,AIG1,PLCB1,LRAT,SMPDL3B,GPLD1,DAGLA,PLPPR2,ACER2,MFSD2A,OSBPL5,SRD5A3,XBP1,PIP5KL1,PLD1,CERS1,PTGES,ACSM3 |
| 4.014e-02 | -3.22 | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_PLASMABLAST_UP | 370 | 47 | 17377 | 1707 |
NBL1,ALOX5AP,ENO2,DOCK1,CBS,TJP1,DDR1,SATB1,PFN2,COL14A1,RPL34,CHN1,NELL2,CDR2L,SCN1B,RPS11,NCAM1,STXBP1,RAPGEF5,RBMS2,PCSK6,DUSP1,MSX1,ALDH2,CSN2,NR4A1,FEZ1,PRKAR2B,CD40,SKAP1,HERPUD1,SMPDL3B,GPLD1,SNCA,MAPKAPK2,AK1,FGR,RPL28,FBN1,CSF1,PAM,BMP4,TPM1,MMP16,AMPD1,MME,TPT1 |
| 4.018e-02 | -3.21 | embryonic pattern specification | biological process | GO:0009880 | 64 | 11 | 17256 | 1658 |
SMAD3,EPB41L5,LRP6,SATB2,DISP1,NRP1,SMAD6,SEMA3A,COBL,PGAP1,PCSK6 |
| 4.022e-02 | -3.21 | MORF_DCC | MSigDB lists | MORF_DCC | 102 | 16 | 17377 | 1707 |
DOC2A,TRIM9,GPR176,GCNT2,PTPRJ,BMPR2,AKAP5,DCC,MPPED2,OPHN1,ATRNL1,FRK,MYT1,TRPC3,MLLT3,GLDC |
| 4.022e-02 | -3.21 | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | 86 | 14 | 17377 | 1707 |
CD55,GPRC5B,MSMO1,P4HA2,PTPN21,HK2,RAB31,BNIP3L,DUSP9,COL18A1,SGK1,DHCR7,ATP2B1,DUSP1 |
| 4.022e-02 | -3.21 | KEGG_RIBOSOME | MSigDB lists | KEGG_RIBOSOME | 86 | 14 | 17377 | 1707 |
RPS20,RSL24D1,RPL26,RPL12,RPL28,RPS11,RPL21,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPL34,RPS13 |
| 4.022e-02 | -3.21 | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_DN | MSigDB lists | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_DN | 86 | 14 | 17377 | 1707 |
CREB3L2,CACHD1,GPM6A,GSTM2,CNTN4,BACH2,LRRN1,SLC27A2,CACNB2,PDE10A,ADCY1,DENND1C,TTC39A,SLC43A1 |
| 4.022e-02 | -3.21 | SASSON_RESPONSE_TO_FORSKOLIN_UP | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_UP | 86 | 14 | 17377 | 1707 |
CD55,GPRC5B,MSMO1,P4HA2,PTPN21,HK2,BNIP3L,COL18A1,DUSP9,SGK1,CHUK,DHCR7,ATP2B1,DUSP1 |
| 4.024e-02 | -3.21 | transforming growth factor beta receptor binding | molecular function | GO:0005160 | 48 | 9 | 17224 | 1680 |
SMAD3,INHBC,TGFBR3,MSTN,INHBE,RASL11B,BMP4,SMAD6,BMP6 |
| 4.025e-02 | -3.21 | GO_FATTY_ACID_METABOLIC_PROCESS | MSigDB lists | GO_FATTY_ACID_METABOLIC_PROCESS | 281 | 37 | 17377 | 1707 |
PLA2G4A,PRKAA2,ACSL1,ELOVL4,ALOX5AP,EHHADH,CYP2J2,ELOVL7,OLAH,CYP4V2,STAT5B,SCD,LPIN3,MSMO1,FAAH2,GHR,SYK,CYP1B1,FADS1,SESN2,SLC27A2,ELOVL3,FASN,PRKAR2B,SNCA,MAPKAPK2,DAGLA,XBP1,BDH2,PAM,TNFRSF1A,HPGD,CYP2U1,PPARGC1A,PTGES,CRYL1,ACSM3 |
| 4.032e-02 | -3.21 | GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_CELL_FATE_COMMITMENT | MSigDB lists | GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_CELL_FATE_COMMITMENT | 20 | 5 | 17377 | 1707 |
NKX6-1,CEBPB,DLX2,BMP4,CHD5 |
| 4.032e-02 | -3.21 | MODULE_186 | MSigDB lists | MODULE_186 | 20 | 5 | 17377 | 1707 |
SLC7A2,SLC1A3,SLC16A2,SLC7A5,ABCG1 |
| 4.032e-02 | -3.21 | GO_VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY | MSigDB lists | GO_VOLTAGE_GATED_SODIUM_CHANNEL_ACTIVITY | 20 | 5 | 17377 | 1707 |
SCN5A,SCN2A,SCN1B,SCN8A,SCN3A |
| 4.032e-02 | -3.21 | GO_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS | MSigDB lists | GO_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS | 20 | 5 | 17377 | 1707 |
UNC13B,SEPT5,STXBP1,PFN2,LRRK2 |
| 4.032e-02 | -3.21 | GO_GMP_METABOLIC_PROCESS | MSigDB lists | GO_GMP_METABOLIC_PROCESS | 20 | 5 | 17377 | 1707 |
DLG2,PRTFDC1,MPP1,MAGI3,MPP2 |
| 4.032e-02 | -3.21 | SCHURINGA_STAT5A_TARGETS_UP | MSigDB lists | SCHURINGA_STAT5A_TARGETS_UP | 20 | 5 | 17377 | 1707 |
MAOA,HBE1,KLHL29,RAC3,LEPR |
| 4.032e-02 | -3.21 | TIAN_TNF_SIGNALING_NOT_VIA_NFKB | MSigDB lists | TIAN_TNF_SIGNALING_NOT_VIA_NFKB | 20 | 5 | 17377 | 1707 |
RGS16,INSIG1,GATA2,NR4A1,PTGES |
| 4.032e-02 | -3.21 | NIELSEN_LEIOMYOSARCOMA_CNN1_DN | MSigDB lists | NIELSEN_LEIOMYOSARCOMA_CNN1_DN | 20 | 5 | 17377 | 1707 |
UACA,TOX,PLAGL1,SPRY2,FRAS1 |
| 4.032e-02 | -3.21 | DING_LUNG_CANCER_BY_MUTATION_RATE | MSigDB lists | DING_LUNG_CANCER_BY_MUTATION_RATE | 20 | 5 | 17377 | 1707 |
FGFR4,ROBO2,DDR1,PTPRD,MAST4 |
| 4.032e-02 | -3.21 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_TOP20_UP | 20 | 5 | 17377 | 1707 |
NDRG2,CA8,FAM174B,PHLDA2,EPS8 |
| 4.032e-02 | -3.21 | GO_INTRACELLULAR_LIPID_TRANSPORT | MSigDB lists | GO_INTRACELLULAR_LIPID_TRANSPORT | 20 | 5 | 17377 | 1707 |
LRP6,PRKAA2,NPC2,PLEKHA8,ABCG1 |
| 4.032e-02 | -3.21 | GO_MIDDLE_EAR_MORPHOGENESIS | MSigDB lists | GO_MIDDLE_EAR_MORPHOGENESIS | 20 | 5 | 17377 | 1707 |
MSX1,INSIG1,NKX3-2,FGFR1,SIX2 |
| 4.034e-02 | -3.21 | GO_MYELOID_LEUKOCYTE_ACTIVATION | MSigDB lists | GO_MYELOID_LEUKOCYTE_ACTIVATION | 94 | 15 | 17377 | 1707 |
TLR3,GATA2,CSF1,PRKCD,VAMP8,PREX1,SLC7A2,LCP2,BATF,TLR4,DOCK2,SYK,RASGRP1,SNCA,BATF3 |
| 4.034e-02 | -3.21 | V$PAX6_01 | MSigDB lists | V$PAX6_01 | 94 | 15 | 17377 | 1707 |
ARHGAP26,GPM6A,C1orf21,JPH1,CHRDL1,ACVR2A,ZBTB20,HRK,BEND4,SERPINI1,ETV1,METAP1D,FSTL5,FILIP1,NKX2-1 |
| 4.034e-02 | -3.21 | BROWNE_HCMV_INFECTION_12HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_12HR_DN | 94 | 15 | 17377 | 1707 |
RIN2,TRIM2,ZNF516,TUBA1A,CACNA1E,AKT3,EXOC6B,FHL2,VWA5A,DENND3,MAST4,SMAD6,MID1,ZIC1,TBC1D8 |
| 4.038e-02 | -3.21 | GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 589 | 71 | 17377 | 1707 |
AKAP5,VAMP8,RGS20,TLR3,SEC16B,UNC13B,PMAIP1,DACT1,REEP1,TRPC1,DAB2IP,PDE4D,TLR4,SNAI2,GAB2,FZD1,FER,ANK2,PTPN6,LRRK2,JPH1,BNIP3L,ELMOD1,GSTO1,PRKCQ,ASPH,SNCA,SMAD3,CXCL10,INSIG1,PEMT,WWTR1,BBC3,INPP5F,BMPR1A,ATG5,SEPT5,MXI1,C1QTNF3,BVES,UBASH3B,IPO5,UBAC2,BTBD9,GAS6,PFN2,MLC1,BMP6,IL18R1,NEDD4,GAS1,PRKCD,SREBF1,STXBP1,SYK,FES,GSTM2,LITAF,WWC1,RYR2,MAP1B,ZIC1,FGR,RPL28,XBP1,BMP4,TRPC3,IL9R,SFN,PKIA,STOM |
| 4.040e-02 | -3.21 | PEDRIOLI_MIR31_TARGETS_UP | MSigDB lists | PEDRIOLI_MIR31_TARGETS_UP | 194 | 27 | 17377 | 1707 |
MOB1B,MAN2B2,PTCH2,PHACTR3,PCDH10,MCF2L2,FAM84A,FASN,GATA3,OBSCN,GABRR2,ATOH1,ASPH,DDIT4,ABI3BP,ERN1,C1orf53,RAB26,RGS10,SLC2A12,PDE4D,KLHL29,ATP2B4,PKIA,IGFBP3,HS6ST3,GLDC |
| 4.040e-02 | -3.21 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | 194 | 27 | 17377 | 1707 |
MID2,ITGB7,FGF13,SH2D2A,PRSS12,RECK,PTPN13,CRIP2,GATA3,GSTO1,DOCK5,CD7,SLCO3A1,AARS,IL18R1,HOPX,TXNDC5,ENPP1,FGR,EOMES,PAM,TMEM37,NRP1,ERRFI1,SNX10,ZFP36L2,FRMD5 |
| 4.040e-02 | -3.21 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | 194 | 27 | 17377 | 1707 |
FARP1,RHOBTB1,ST6GAL1,EPS8,HERC5,NPM1,CBS,FERMT2,SPATS2L,NHP2,DDR1,JAM3,FGFR1,QPRT,PLS3,HOMER3,SFXN1,DEXI,CXCL10,TRIB3,GBP1,CSF1,PPFIBP1,EIF4EBP1,LAPTM4B,HGF,PLTP |
| 4.040e-02 | -3.21 | GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_UP | MSigDB lists | GSE28783_ANTI_MIR33_VS_CTRL_ATHEROSCLEROSIS_MACROPHAGE_UP | 194 | 27 | 17377 | 1707 |
FARP1,RASAL2,PTPN13,ANK2,EFNA3,SELL,KCTD12,MAPK4,SLC1A3,GUCY1A2,PCLO,BMP6,CHST10,PPP2R3A,GPR37,SYCP2,ENPP1,PMAIP1,KCNS3,MYOM2,RPL4,UNC5B,GFI1,PTPRE,RAB30,IGSF3,PNMA2 |
| 4.046e-02 | -3.21 | regulation of protein localization | biological process | GO:0032880 | 917 | 104 | 17256 | 1658 |
EPHA3,EXPH5,PRKN,SORBS1,LGR4,TRIM16,AKAP5,CELSR3,VAMP8,LILRB1,GATA3,CHUK,ITPR2,ABAT,NRXN1,PRKCA,BAG3,UNC13B,SEC16B,TCAF2,PMAIP1,KCNS3,MARCKS,MYRIP,TLR4,IL1RAP,RASGRP1,DPP10,SESN2,GAPDH,ACVR1C,PFKFB2,WLS,LRRK2,BNIP3L,CD40,SERGEF,GNAI1,IRS2,SMAD3,GSN,INSIG1,MAP2,GBP1,PAM,BBC3,DISP1,ATG5,TNFSF4,PRKAA2,TENM1,NECAB2,FN1,STXBP5L,C1QTNF3,TBC1D1,FBXO4,APBB1,LRP4,IPO5,UBAC2,ARL2,GAS6,GPSM2,NDFIP2,BMP6,MCU,NKX6-1,RAB11FIP5,MAP1A,PRKCD,SREBF1,PCK2,SYK,PARP9,HMGCR,EPB41L5,PAK1,TRPM4,VEGFC,B9D1,ATP5IF1,BDNF,RHOQ,CACNA1E,SYBU,RAPGEF4,NSD2,PLS1,SNAP25,RACK1,TLR6,ZIC1,GPLD1,FGR,ICA1,RIPOR2,TERT,XBP1,BMP4,CDH2,PKIA,SFN,STOM |
| 4.049e-02 | -3.21 | GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_DN | MSigDB lists | GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_DN | 160 | 23 | 17377 | 1707 |
SERINC5,EHHADH,TCP11L2,TMEM43,SLC27A2,YPEL2,SPATA13,RNF125,PRKCQ,SNTB1,SKAP1,OTUD1,HPS1,MAP2K6,PPFIBP1,PLK2,FAM107B,BCL6,MYO3B,RUNDC3B,ACVR2A,ST8SIA1,HACE1 |
| 4.054e-02 | -3.21 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_IV | 48 | 9 | 17385 | 1698 |
MN1,INTU,SCN5A,ATPAF2,FAT4,RASA3,KIAA1549,SYK,DCBLD1 |
| 4.058e-02 | -3.20 | 7tm_2 | pfam domains | PF00002 | 48 | 9 | 17054 | 1666 |
CALCRL,ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRG6,ADGRL2,ADGRB2,ADGRL1 |
| 4.058e-02 | -3.20 | PX | pfam domains | PF00787 | 48 | 9 | 17054 | 1666 |
SGK3,PIK3C2B,ARHGAP32,PLD1,SH3PXD2B,SNX9,SNX10,PXDC1,SNX7 |
| 4.061e-02 | -3.20 | GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 177 | 25 | 17377 | 1707 |
VAV3,FARP1,RASAL2,ARHGEF11,MCF2L2,CYTH3,SPATA13,PREX1,PSD3,RASA3,OBSCN,ARHGEF26,TIAM2,ARHGEF10L,RALGPS2,RASGRF2,MCF2L,CSF1,BCL6,PLEKHG1,DAB2IP,IQSEC2,CDH2,SPRY2,RASGRP1 |
| 4.061e-02 | -3.20 | GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN | 177 | 25 | 17377 | 1707 |
FADS1,EVL,PDK1,CELSR1,FGF13,CHCHD7,CKAP2,RECK,TES,STAT4,PTPN13,GATA3,SATB1,IRS2,SPEG,ID3,SEMA4F,FBN1,RGS10,SGK1,NRP1,MYO6,GFI1,PSPH,HMGCR |
| 4.061e-02 | -3.20 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_UP | 177 | 25 | 17377 | 1707 |
CGN,BTC,RASAL2,KLHL23,GRIK2,NPM3,CYTH3,FHDC1,FGF17,APBA1,ARRDC4,KCNC4,PFN2,TBC1D16,DKK1,ARHGEF10L,ATP7B,ZIC5,CCDC146,C1orf53,STXBP1,DOCK6,MED12L,ZNF629,HRASLS |
| 4.061e-02 | -3.20 | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 177 | 25 | 17377 | 1707 |
BCL7A,APBB1,EPS8,LRMP,UBAC2,ITPR2,ATP1B1,C3orf70,PRKCA,MAGI3,EBF1,ENTPD1,PPM1E,ENPP6,PRKCB,RAI14,SGK1,UACA,TSPAN13,DYNC2H1,TMEM132E,RRAS2,TLR4,GFRA1,CACNA2D1 |
| 4.062e-02 | -3.20 | xenobiotic metabolic process | biological process | GO:0006805 | 121 | 18 | 17256 | 1658 |
GSTM2,ACSL1,CYP2J2,MGST3,GSTM4,GSTO1,STAT5B,PHGDH,CYP26A1,AHRR,GSTO2,BCHE,GHR,GSTM3,CYP2U1,NCEH1,CYP1B1,CES3 |
| 4.062e-02 | -3.20 | nephron development | biological process | GO:0072006 | 121 | 18 | 17256 | 1658 |
COL4A3,LGR4,KLHL3,COL4A4,DCHS1,GATA3,WNT11,FAT4,MYC,HEYL,WWTR1,ACTA2,BMP4,MAGI2,PDGFRB,SIX2,POU3F3,MEF2C |
| 4.065e-02 | -3.20 | tissue migration | biological process | GO:0090130 | 88 | 14 | 17256 | 1658 |
EPB41L5,EFNB2,PXN,ID1,PKN3,NR4A1,APELA,ACTA2,PKN1,NRP1,SLIT2,CYP1B1,GPLD1,NOS3 |
| 4.071e-02 | -3.20 | platelet-derived growth factor receptor binding | molecular function | GO:0005161 | 14 | 4 | 17224 | 1680 |
PTPRJ,ITGB3,PDGFRB,ERN1 |
| 4.071e-02 | -3.20 | GTPase inhibitor activity | molecular function | GO:0005095 | 14 | 4 | 17224 | 1680 |
ARL2,TNK2,SLIT2,IPO5 |
| 4.071e-02 | -3.20 | low-density lipoprotein particle receptor activity | molecular function | GO:0005041 | 14 | 4 | 17224 | 1680 |
LRP6,LDLR,LRP12,VLDLR |
| 4.071e-02 | -3.20 | GDP-dissociation inhibitor activity | molecular function | GO:0005092 | 14 | 4 | 17224 | 1680 |
GPSM2,SESN2,SH3BP4,GPSM1 |
| 4.072e-02 | -3.20 | male sex differentiation | biological process | GO:0046661 | 155 | 22 | 17256 | 1658 |
COL9A3,LGR4,BIK,ARID5B,DHCR24,GATA3,STAT5B,AGO4,PLEKHA1,FNDC3A,BMP6,SYCP2,HMGCS1,TLR3,LRRC6,CTSV,ACVR2A,HOXD13,BMPR1A,YBX3,PDGFRB,NKX2-1 |
| 4.075e-02 | -3.20 | cellular response to monosaccharide stimulus | biological process | GO:0071326 | 72 | 12 | 17256 | 1658 |
PRKAA2,IRS2,RAB11FIP5,IGF1R,UNC13B,XBP1,ERN1,PTPRN2,GAS6,RACK1,PCK2,PPARGC1A |
| 4.077e-02 | -3.20 | multivesicular body | cellular component | GO:0005771 | 42 | 8 | 18223 | 1724 |
LAPTM4B,STEAP3,NDFIP2,RAB27B,LRAT,BACE1,LRRK2,TPT1 |
| 4.082e-02 | -3.20 | CCAWYNNGAAR_UNKNOWN | MSigDB lists | CCAWYNNGAAR_UNKNOWN | 135 | 20 | 17377 | 1707 |
USP2,TUBA1A,FOXN3,ATOH1,NRXN1,MECOM,FOXP2,PPM1E,SLC22A17,SH3RF1,PRCP,MFSD2A,EIF1,STARD4,GAN,BCL6,MORN2,VGLL4,NR3C2,SFN |
| 4.082e-02 | -3.20 | GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_UP | MSigDB lists | GSE12003_4D_VS_8D_CULTURE_MIR223_KO_BM_PROGENITOR_UP | 135 | 20 | 17377 | 1707 |
MVK,GCNT2,COL4A3,CLSTN2,ACVR2B,AMIGO1,SNAP25,NEGR1,PDZD7,GHR,EMILIN2,SLC2A6,LAPTM4B,PTPRS,MPDZ,TMOD2,MARCKS,OCLN,CKAP4,CNTN1 |
| 4.087e-02 | -3.20 | hematopoietic progenitor cell differentiation | biological process | GO:0002244 | 80 | 13 | 17256 | 1658 |
PTPRC,EEF2,BVES,PTPN6,MLF1,GATA3,BMP4,PYGO1,BATF,HERC6,JAM3,STON2,EML1 |
| 4.091e-02 | -3.20 | PhoLip_ATPase_C | pfam domains | PF16212 | 14 | 4 | 17054 | 1666 |
ATP11A,ATP9A,ATP10D,ATP8A1 |
| 4.091e-02 | -3.20 | PhoLip_ATPase_N | pfam domains | PF16209 | 14 | 4 | 17054 | 1666 |
ATP11A,ATP9A,ATP10D,ATP8A1 |
| 4.091e-02 | -3.20 | Na_H_Exchanger | pfam domains | PF00999 | 14 | 4 | 17054 | 1666 |
TMCO3,SLC9C1,SLC9B1,SLC9A7 |
| 4.091e-02 | -3.20 | GATA | pfam domains | PF00320 | 14 | 4 | 17054 | 1666 |
GATA3,GATA2,RERE,TRPS1 |
| 4.091e-02 | -3.20 | DHC_N2 | pfam domains | PF08393 | 14 | 4 | 17054 | 1666 |
DYNC2H1,DNHD1,DNAH5,DNAH6 |
| 4.091e-02 | -3.20 | Ldl_recept_b | pfam domains | PF00058 | 14 | 4 | 17054 | 1666 |
LRP6,LRP4,VLDLR,LDLR |
| 4.091e-02 | -3.20 | BEX | pfam domains | PF04538 | 14 | 4 | 17054 | 1666 |
TCEAL3,BEX4,BEX3,BEX2 |
| 4.091e-02 | -3.20 | Gelsolin | pfam domains | PF00626 | 14 | 4 | 17054 | 1666 |
SVIL,GSN,SEC24D,SCIN |
| 4.108e-02 | -3.19 | circulatory system process | biological process | GO:0003013 | 388 | 48 | 17256 | 1658 |
SCN5A,BMPR2,PKP2,GAS6,P2RY1,ABAT,KCNN2,SCN1B,CACNB2,PRKG1,ACTA2,SGK1,ADCY6,PDE4D,SLIT2,CHRM3,NOS3,TBC1D8,HMGCR,TRPM4,VEGFC,MYLK3,COL4A3,ADM2,ANK2,FGF12,RYR2,KCND3,ATP1B1,DOCK5,HEG1,GJC1,HTR7,SMAD3,DDAH1,CXCL10,KCNMB4,PTPRJ,PRCP,MAP2K6,ADRB1,OXTR,ATG5,TPM1,CACNA2D1,MME,ACSM3,PCSK5 |
| 4.108e-02 | -3.19 | SSD | prosite domains | PS50156 | 13 | 4 | 12060 | 1278 |
PTCH2,DISP1,DISP2,HMGCR |
| 4.115e-02 | -3.19 | Phox | interpro domains | IPR001683 | 48 | 9 | 18492 | 1811 |
SGK3,PIK3C2B,ARHGAP32,PLD1,SH3PXD2B,SNX9,SNX10,PXDC1,SNX7 |
| 4.115e-02 | -3.19 | GPCR_2_secretin-like | interpro domains | IPR000832 | 48 | 9 | 18492 | 1811 |
CALCRL,ADGRA3,ADGRB3,CELSR1,CELSR3,ADGRG6,ADGRL2,ADGRB2,ADGRL1 |
| 4.124e-02 | -3.19 | NPHP3 (nephrocystin 3) | protein interactions | 27031 | 26 | 6 | 17029 | 1718 |
PRKG2,PDE8A,KLHL29,FMNL2,NPHP1,PALD1 |
| 4.124e-02 | -3.19 | SGPP1 (sphingosine-1-phosphate phosphatase 1) | protein interactions | 81537 | 26 | 6 | 17029 | 1718 |
SLC7A1,GDPD5,SLC39A8,CHST10,MCOLN3,LAMP3 |
| 4.124e-02 | -3.19 | RETSAT (retinol saturase) | protein interactions | 54884 | 26 | 6 | 17029 | 1718 |
EFNB2,GDPD5,TSPAN17,IL9R,MCOLN3,KCNS3 |
| 4.124e-02 | -3.19 | ARHGEF11 (Rho guanine nucleotide exchange factor 11) | protein interactions | 9826 | 26 | 6 | 17029 | 1718 |
ARAP2,LPAR2,MAP1A,ARHGEF11,PAK5,MAP1B |
| 4.124e-02 | -3.19 | P-type_ATPase_N | interpro domains | IPR032631 | 14 | 4 | 18492 | 1811 |
ATP11A,ATP9A,ATP10D,ATP8A1 |
| 4.124e-02 | -3.19 | RasGAP_CS | interpro domains | IPR023152 | 14 | 4 | 18492 | 1811 |
RASA3,DAB2IP,IQGAP3,RASAL2 |
| 4.124e-02 | -3.19 | Cation/H_exchanger | interpro domains | IPR006153 | 14 | 4 | 18492 | 1811 |
TMCO3,SLC9C1,SLC9B1,SLC9A7 |
| 4.124e-02 | -3.19 | TF_A-like/BEX | interpro domains | IPR021156 | 14 | 4 | 18492 | 1811 |
TCEAL3,BEX4,BEX3,BEX2 |
| 4.124e-02 | -3.19 | P-type_ATPase_IV | interpro domains | IPR006539 | 14 | 4 | 18492 | 1811 |
ATP11A,ATP9A,ATP10D,ATP8A1 |
| 4.124e-02 | -3.19 | Neurexin-like | interpro domains | IPR003585 | 14 | 4 | 18492 | 1811 |
SDC3,CADM2,GYPC,NRXN1 |
| 4.124e-02 | -3.19 | P_typ_ATPase_c | interpro domains | IPR032630 | 14 | 4 | 18492 | 1811 |
ATP11A,ATP9A,ATP10D,ATP8A1 |
| 4.124e-02 | -3.19 | Gelsolin-like_dom | interpro domains | IPR007123 | 14 | 4 | 18492 | 1811 |
SVIL,GSN,SEC24D,SCIN |
| 4.124e-02 | -3.19 | Dynein_heavy_dom-2 | interpro domains | IPR013602 | 14 | 4 | 18492 | 1811 |
DYNC2H1,DNHD1,DNAH5,DNAH6 |
| 4.124e-02 | -3.19 | GLA-like_dom_SF | interpro domains | IPR035972 | 14 | 4 | 18492 | 1811 |
PRRG1,PROS1,GAS6,PRRG4 |
| 4.124e-02 | -3.19 | GLA_domain | interpro domains | IPR000294 | 14 | 4 | 18492 | 1811 |
PRRG1,PROS1,GAS6,PRRG4 |
| 4.134e-02 | -3.19 | AB_hydrolase | interpro domains | IPR029058 | 119 | 18 | 18492 | 1811 |
DPP10,PRSS16,OLAH,ABHD13,FASN,NLGN4X,NDRG2,ABHD4,ABHD6,PGAP1,DAGLA,TMEM53,CPVL,BCHE,PRCP,NCEH1,ESD,CES3 |
| 4.139e-02 | -3.18 | secretion | biological process | GO:0046903 | 1092 | 122 | 17256 | 1658 |
PLA2G4A,DOC2A,FRMPD3,SCAMP1,PRSS12,SYT12,ATP8A1,DNAJC3,VAMP8,LILRB1,GATA3,STAT5B,CANX,SYT14,NRXN1,LCP2,DDR1,PCLO,DOCK2,CBLN1,PCDH7,TXNDC5,CD53,SCIN,UNC13B,PPFIA2,ALDOC,ITGB3,RAB26,LIN7A,SCRN1,STEAP3,PROS1,POU2F2,ARL4D,SYNGR3,RAB27B,TLR4,IL1RAP,RASGRP1,GCA,CD55,CSN2,ABCC4,FZD4,WLS,PTPN6,EXOC6B,LRMP,ABCC2,ACVR2B,RARRES2,COTL1,DSP,FRK,TRIM9,GSN,PTPRJ,HPSE,NCKAP1L,ATP7B,ALDOA,PAM,HGF,OXTR,SEPT5,TC2N,PCSK5,TYRO3,SLC6A9,FN1,STXBP5L,LGALS3,STXBP6,TNFSF13B,SELL,GAS6,SLC1A3,APBA1,SELENOP,ARHGAP44,RAB11FIP5,MCOLN2,EEF2,CA2,PRKCD,CADPS2,SLCO4C1,AGL,STXBP1,SYK,CKAP4,RIMS2,CHRM3,PCSK6,PAK1,VEGFC,QSOX1,RAB3B,PNP,SLC27A2,RAPGEF4,PPFIA4,PHACTR2,NPC2,SNAP25,ATP11A,TLR6,ILDR2,PTPRC,FGR,PRCP,RAB31,HK2,SELENOM,PTPRN2,PLD1,JHY,SLC1A5,MME,STOM,SNPH |
| 4.153e-02 | -3.18 | human chr4q21.21 | chromosome location | human chr4q21.21 | 18 | 4 | 26185 | 1967 |
PRKG2,PRDM8,ANTXR2,FRAS1 |
| 4.153e-02 | -3.18 | human chr13q14.13 | chromosome location | human chr13q14.13 | 18 | 4 | 26185 | 1967 |
CPB2-AS1,COG3,TPT1-AS1,TPT1 |
| 4.153e-02 | -3.18 | human chr2q23.3 | chromosome location | human chr2q23.3 | 18 | 4 | 26185 | 1967 |
RND3,CACNB4,FMNL2,NEB |
| 4.157e-02 | -3.18 | GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | 152 | 22 | 17377 | 1707 |
SUSD3,TNK2,ANKRD13B,NR4A1,EFNA3,WWC1,SFXN3,FAM81A,RGS7,ILDR2,GPLD1,HTR7,GRIK4,PCGF2,CHRDL1,DAB2IP,MYH15,TMEM132E,CERS1,MORN4,ZFP36L2,MAST1 |
| 4.157e-02 | -3.18 | GSE37301_PRO_BCELL_VS_CD4_TCELL_DN | MSigDB lists | GSE37301_PRO_BCELL_VS_CD4_TCELL_DN | 152 | 22 | 17377 | 1707 |
DBN1,TMEM63C,EVL,MARK1,KLHL3,MYO10,WLS,ST6GAL1,CYTH3,DNAJC6,PPFIBP2,CLSTN2,PRKCQ,CANX,MTUS1,SOAT2,ZIC5,MARCH3,IPCEF1,NRP1,RRAGD,GAB2 |
| 4.157e-02 | -3.18 | MODULE_111 | MSigDB lists | MODULE_111 | 152 | 22 | 17377 | 1707 |
RGS16,MVK,PXN,SLC6A9,PTPRU,STAT4,EFNA3,APBA1,SMPDL3B,NELL2,KCNJ4,FGR,BNIP1,NCKAP1L,SCN1B,GATA2,MPP2,STXBP1,RAPGEF5,MME,CNTN1,MEF2C |
| 4.157e-02 | -3.18 | GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_DN | MSigDB lists | GSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_DN | 152 | 22 | 17377 | 1707 |
UST,GCNT2,PTPRU,KLHL13,MPP1,COL4A4,TCF24,ARHGAP22,AK4,KCNC4,DCBLD2,BCL11A,KCTD15,TLR3,RPL12,SLC22A17,PKN3,SMTN,DBP,SMAD6,LZTS1,HRASLS |
| 4.159e-02 | -3.18 | AGE-RAGE signaling pathway in diabetic complications | KEGG pathways | ko04933 | 99 | 16 | 7161 | 730 |
VEGFC,FN1,COL4A3,COL4A4,COL4A5,STAT5B,PRKCA,PLCB1,F3,SMAD3,PRKCB,AKT3,PRKCD,MAPK13,MAPK10,NOS3 |
| 4.159e-02 | -3.18 | AGE-RAGE signaling pathway in diabetic complications | KEGG pathways | hsa04933 | 99 | 16 | 7161 | 730 |
VEGFC,FN1,COL4A3,COL4A4,COL4A5,STAT5B,PRKCA,PLCB1,F3,SMAD3,PRKCB,AKT3,PRKCD,MAPK13,MAPK10,NOS3 |
| 4.159e-02 | -3.18 | human chr2p16.1 | chromosome location | human chr2p16.1 | 26 | 5 | 26185 | 1967 |
EFEMP1,CCDC85A,EML6,REL,BCL11A |
| 4.159e-02 | -3.18 | human chr4q32.1 | chromosome location | human chr4q32.1 | 26 | 5 | 26185 | 1967 |
FAM198B,TDO2,LRAT,RAPGEF2,MAP9 |
| 4.159e-02 | -3.18 | human chr18q12.1 | chromosome location | human chr18q12.1 | 26 | 5 | 26185 | 1967 |
RNF125,GAREM1,CDH2,DSG2,B4GALT6 |
| 4.161e-02 | -3.18 | PEBP1 (phosphatidylethanolamine binding protein 1) | protein interactions | 5037 | 54 | 10 | 17029 | 1718 |
BAG3,CACHD1,ASNS,LGALS3,PRKCB,PRKCD,STC2,CHUK,PRKCA,UCHL3 |
| 4.161e-02 | -3.18 | MOB1A (MOB kinase activator 1A) | protein interactions | 55233 | 54 | 10 | 17029 | 1718 |
MOB1B,LATS2,DOCK7,TDO2,HECW2,SAV1,SEPT3,DOCK6,DOCK8,SKI |
| 4.164e-02 | -3.18 | GO_OXYGEN_TRANSPORT | MSigDB lists | GO_OXYGEN_TRANSPORT | 14 | 4 | 17377 | 1707 |
HBE1,HBG2,IPCEF1,MYC |
| 4.164e-02 | -3.18 | GO_PRIMARY_AMINO_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_PRIMARY_AMINO_COMPOUND_METABOLIC_PROCESS | 14 | 4 | 17377 | 1707 |
MAOA,BTBD9,RNF180,PDE1B |
| 4.164e-02 | -3.18 | SABATES_COLORECTAL_ADENOMA_SIZE_DN | MSigDB lists | SABATES_COLORECTAL_ADENOMA_SIZE_DN | 14 | 4 | 17377 | 1707 |
MAOA,BNIP1,PDE4D,RCAN3 |
| 4.164e-02 | -3.18 | SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_UP | MSigDB lists | SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_UP | 14 | 4 | 17377 | 1707 |
ATP1B1,NCAM1,PCLO,KAZN |
| 4.164e-02 | -3.18 | GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_EPITHELIAL_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 14 | 4 | 17377 | 1707 |
GATA3,YAP1,FAT4,WWTR1 |
| 4.164e-02 | -3.18 | chr13q33 | MSigDB lists | chr13q33 | 14 | 4 | 17377 | 1707 |
EFNB2,ITGBL1,FAM155A,ABHD13 |
| 4.164e-02 | -3.18 | GO_SERINE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_SERINE_FAMILY_AMINO_ACID_BIOSYNTHETIC_PROCESS | 14 | 4 | 17377 | 1707 |
CBS,PHGDH,PSPH,CTH |
| 4.164e-02 | -3.18 | GO_GTPASE_INHIBITOR_ACTIVITY | MSigDB lists | GO_GTPASE_INHIBITOR_ACTIVITY | 14 | 4 | 17377 | 1707 |
ARL2,TNK2,SLIT2,IPO5 |
| 4.164e-02 | -3.18 | GO_REGULATION_OF_PROTEIN_HOMOOLIGOMERIZATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_HOMOOLIGOMERIZATION | 14 | 4 | 17377 | 1707 |
BBC3,HRK,BIK,BCL11A |
| 4.164e-02 | -3.18 | HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_DN | MSigDB lists | HOLLEMAN_VINCRISTINE_RESISTANCE_B_ALL_DN | 14 | 4 | 17377 | 1707 |
VIM,RPL12,RPS12,RPS11 |
| 4.164e-02 | -3.18 | GO_HEART_TRABECULA_FORMATION | MSigDB lists | GO_HEART_TRABECULA_FORMATION | 14 | 4 | 17377 | 1707 |
OVOL2,TGFBR3,HEY1,FHL2 |
| 4.164e-02 | -3.18 | GO_FRUCTOSE_METABOLIC_PROCESS | MSigDB lists | GO_FRUCTOSE_METABOLIC_PROCESS | 14 | 4 | 17377 | 1707 |
PFKFB4,PFKFB2,ALDOC,ALDOA |
| 4.164e-02 | -3.18 | GO_LINOLEIC_ACID_METABOLIC_PROCESS | MSigDB lists | GO_LINOLEIC_ACID_METABOLIC_PROCESS | 14 | 4 | 17377 | 1707 |
FADS1,ACSL1,CYP2J2,ELOVL3 |
| 4.164e-02 | -3.18 | GO_DETECTION_OF_CALCIUM_ION | MSigDB lists | GO_DETECTION_OF_CALCIUM_ION | 14 | 4 | 17377 | 1707 |
RYR2,KCNMB4,ASPH,KCNMB3 |
| 4.164e-02 | -3.18 | TSUNODA_CISPLATIN_RESISTANCE_UP | MSigDB lists | TSUNODA_CISPLATIN_RESISTANCE_UP | 14 | 4 | 17377 | 1707 |
EFEMP1,VIM,VAV3,INSIG1 |
| 4.164e-02 | -3.18 | GO_FIBRIL | MSigDB lists | GO_FIBRIL | 14 | 4 | 17377 | 1707 |
SLC1A3,FBN1,THSD4,SNCA |
| 4.164e-02 | -3.18 | ROETH_TERT_TARGETS_UP | MSigDB lists | ROETH_TERT_TARGETS_UP | 14 | 4 | 17377 | 1707 |
PLA2G4A,HERC5,HERC6,HEG1 |
| 4.164e-02 | -3.18 | GO_CELLULAR_RESPONSE_TO_STEROL | MSigDB lists | GO_CELLULAR_RESPONSE_TO_STEROL | 14 | 4 | 17377 | 1707 |
LRP6,HMGCS1,MLC1,GPLD1 |
| 4.164e-02 | -3.18 | EHRLICH_ICF_SYNDROM_DN | MSigDB lists | EHRLICH_ICF_SYNDROM_DN | 14 | 4 | 17377 | 1707 |
ITGB7,ID3,TNFRSF17,MEF2C |
| 4.164e-02 | -3.18 | ABBUD_LIF_SIGNALING_2_UP | MSigDB lists | ABBUD_LIF_SIGNALING_2_UP | 14 | 4 | 17377 | 1707 |
ATP1B1,PPP2R2B,NRP1,FGFR1 |
| 4.164e-02 | -3.18 | GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING | MSigDB lists | GO_PLATELET_DERIVED_GROWTH_FACTOR_RECEPTOR_BINDING | 14 | 4 | 17377 | 1707 |
TYMP,PTPRJ,ITGB3,PDGFRB |
| 4.164e-02 | -3.18 | GO_CAMP_CATABOLIC_PROCESS | MSigDB lists | GO_CAMP_CATABOLIC_PROCESS | 14 | 4 | 17377 | 1707 |
PDE8A,PDE4D,PDE1B,PDE10A |
| 4.164e-02 | -3.18 | GO_PYRIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_PYRIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS | 14 | 4 | 17377 | 1707 |
NMNAT3,PNP,KMO,QPRT |
| 4.164e-02 | -3.18 | GO_NICOTINAMIDE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NICOTINAMIDE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS | 14 | 4 | 17377 | 1707 |
NMNAT3,PNP,KMO,QPRT |
| 4.164e-02 | -3.18 | GO_EPITHELIAL_CELL_MATURATION | MSigDB lists | GO_EPITHELIAL_CELL_MATURATION | 14 | 4 | 17377 | 1707 |
NKX6-1,TFCP2L1,FOXA1,XBP1 |
| 4.164e-02 | -3.18 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | MSigDB lists | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | 14 | 4 | 17377 | 1707 |
ACSL1,ELOVL4,ELOVL7,ELOVL3 |
| 4.166e-02 | -3.18 | AAGTCCA,MIR-422B,MIR-422A | MSigDB lists | AAGTCCA,MIR-422B,MIR-422A | 63 | 11 | 17377 | 1707 |
SPEG,NSD1,BACE1,C1orf21,DLG2,NTRK3,IQSEC2,FOXG1,HECTD2,FRMD5,MECOM |
| 4.166e-02 | -3.18 | GO_PROTEIN_COMPLEX_SCAFFOLD | MSigDB lists | GO_PROTEIN_COMPLEX_SCAFFOLD | 63 | 11 | 17377 | 1707 |
DISC1,MPP7,SHANK2,LRRK2,DUSP19,PKP2,GRIP1,WWC1,WWC2,MAGI2,MAGI3 |
| 4.166e-02 | -3.18 | GO_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_NOTCH_SIGNALING_PATHWAY | 63 | 11 | 17377 | 1707 |
TSPAN15,GATA2,BCL6,EGFL7,SYNJ2BP,DLX2,CHAC1,OVOL2,GDPD5,TSPAN17,HEY1 |
| 4.166e-02 | -3.18 | GO_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | 63 | 11 | 17377 | 1707 |
NUMBL,PTPRD,AKAP5,VLDLR,SGK1,DAB2IP,MARCKS,PACSIN1,COBL,PPP1R9A,BAIAP2 |
| 4.166e-02 | -3.18 | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_DN | 63 | 11 | 17377 | 1707 |
RHOQ,PLSCR4,IGFBP6,TCEAL3,BNIP3,CPE,TTC28,SLIT2,ATP2B4,GAS1,SNCA |
| 4.166e-02 | -3.18 | regulation of complement activation | biological process | GO:0030449 | 49 | 9 | 17256 | 1658 |
CD55,CFH,C4A,CFHR1,CR2,C1R,PROS1,SUSD4,C4BPB |
| 4.166e-02 | -3.18 | complement activation | biological process | GO:0006956 | 49 | 9 | 17256 | 1658 |
CD55,CFH,CFHR1,C4A,CR2,C1R,SUSD4,COLEC10,C4BPB |
| 4.168e-02 | -3.18 | second-messenger-mediated signaling | biological process | GO:0019932 | 261 | 34 | 17256 | 1658 |
GPR65,MCTP2,RASD1,ITPR2,PCLO,PPP1R9A,ADGRG6,ADGRB2,MCU,BHLHA15,ADGRL1,PRKG1,ADCY6,PDE4D,RCAN3,TSHR,RIMS2,NOS3,TRPM4,GSTM2,ADM2,RAPGEF2,ANK2,RAPGEF4,HOMER2,LRRK2,ADCY1,RYR2,CALCRL,GSTO1,ATP1B1,DDAH1,ADRB1,GRIN2D |
| 4.168e-02 | -3.18 | camera-type eye development | biological process | GO:0043010 | 288 | 37 | 17256 | 1658 |
BCL11B,BMPR2,GATA3,LAMC3,NTRK3,EPHB1,SKI,FOXP2,EFEMP1,IRX5,SLC7A11,TFAP2A,TBC1D32,LRP6,TSPAN12,MYH15,ATP2B1,PDGFRB,CYP1B1,B9D1,RAX,GPM6A,KDM5B,FZD4,SMARCD3,VIM,ACVR2B,SDK1,TSKU,SMAD3,FBN1,WDR19,MYOM2,BMP4,NRP1,NPHP1,ATP2B4 |
| 4.170e-02 | -3.18 | GSE27786_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NKCELL_DN | 186 | 26 | 17377 | 1707 |
RIN2,MXI1,REL,MPP1,KLHL4,LRP4,BLVRB,UBAC2,SCD,MBNL2,RTN1,CEBPB,PTPRC,MAPKAPK2,CA2,TM9SF2,KIAA0355,C1orf21,LRRK1,ALPK1,GEM,ARL4D,VWA5A,SNX10,SLC45A3,SPRY2 |
| 4.170e-02 | -3.18 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_DN | 186 | 26 | 17377 | 1707 |
MICAL2,VAV3,CSN2,CELSR3,PRSS12,CYTH3,HOMER2,DEPTOR,MORC4,GTF2IRD1,PEX5L,KCND3,PFN2,LRAT,SNCA,MSC,IGF1R,RND3,RPS6KL1,EHD3,EEPD1,TRIM3,SFMBT1,LIMCH1,MYT1,KIF1B |
| 4.170e-02 | -3.18 | GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_UP | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_UP | 186 | 26 | 17377 | 1707 |
WASF3,TCTN2,RHOD,ESRRG,RUSC2,VAMP8,ELMOD1,SMARCD3,KCND3,FBXO36,DDR1,RAC3,QPRT,DEXI,NCAM2,MPP7,FABP6,CCDC146,TSC22D1,TSPAN13,CTTN,PERP,RPS23,RBMS2,RAB30,NKX2-1 |
| 4.170e-02 | -3.18 | GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN | MSigDB lists | GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN | 186 | 26 | 17377 | 1707 |
ITGB7,PDK1,SH2D2A,DNAJC3,ARL15,SPATA6,ITGA6,EXOC6B,DNAJC6,ZDHHC15,CALCRL,RNF125,GPSM2,KBTBD11,PEAK1,INPP1,SLCO3A1,IL18R1,BAG3,KCNMB4,TECPR1,EOMES,PELI2,ITGB3,RUNDC3B,SMPDL3A |
| 4.170e-02 | -3.18 | GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP | 186 | 26 | 17377 | 1707 |
SSH3,EVL,ALDH2,DSTN,DNAJC6,TTYH2,SELL,CEBPA,VIM,RARRES2,FAM198B,COTL1,SNX9,CLN5,PGAP1,TSPAN17,TTC30B,CEBPB,MAPKAPK2,BACH2,FRY,SLC7A11,HPS1,TRIM3,KLF9,DIRC2 |
| 4.170e-02 | -3.18 | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP | MSigDB lists | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP | 186 | 26 | 17377 | 1707 |
RGS16,GPM6A,MXI1,CD55,CRIM1,RHOBTB1,ARHGAP32,ROR1,SNAP25,CRYBG3,RASSF8,RPS6KA2,PPP1R26,PRKCB,P4HA2,EIF1,MPPED2,TNFRSF17,PTPRE,MAGI2,FNBP1L,RAPGEF5,CEBPD,CAND2,DOCK9,ABCG1 |
| 4.170e-02 | -3.18 | GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 186 | 26 | 17377 | 1707 |
CARS,C2orf88,MVK,EVL,SORBS1,RHOQ,PNRC1,RNF144A,COBLL1,TBC1D16,PEAK1,FAM174B,IL18R1,METAP1D,ABLIM1,MGAT1,OSBPL5,TSC22D1,COL19A1,DYNC2H1,IPCEF1,RNF157,BTRC,CTNND2,PHC1,MEF2C |
| 4.170e-02 | -3.18 | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN | MSigDB lists | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN | 186 | 26 | 17377 | 1707 |
PLA2G4A,MYO1B,DHCR24,MCTP2,PSD3,FAM198B,ATP11A,BATF,C4orf19,DSP,RASSF8,PTPRC,PTPRJ,IKZF3,IQCH,PPFIBP1,GAN,POF1B,MARCH3,MYOM2,PCOLCE2,THAP10,SHOX2,MAST4,TSHR,OCLN |
| 4.170e-02 | -3.18 | GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_DN | MSigDB lists | GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_DN | 186 | 26 | 17377 | 1707 |
MN1,PTPRU,MYO10,SLC39A8,TES,AK4,HERC5,C1R,IGF2BP2,SLC25A28,PRKCQ,SPATS2L,HERC6,TSKU,BATF3,TYMP,MSC,C1orf21,KLF5,STEAP3,TBC1D9,SNX10,RBMS2,LARP1,ATP2B4,CKAP4 |
| 4.170e-02 | -3.18 | GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN | MSigDB lists | GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN | 186 | 26 | 17377 | 1707 |
NDUFA4L2,TFCP2L1,GPR176,ITGB7,USP2,RUSC2,ZCCHC24,PLAG1,FERMT2,CHAC1,DOCK3,ASPH,CENPV,HSPA12B,GJC1,NKX6-1,SPATA9,RGS17,SH3RF1,PCGF2,COL19A1,SLC2A12,CYP2U1,MORN4,SHOX2,GATM |
| 4.174e-02 | -3.18 | RATTENBACHER_BOUND_BY_CELF1 | MSigDB lists | RATTENBACHER_BOUND_BY_CELF1 | 380 | 48 | 17377 | 1707 |
ESRP1,ARHGAP22,PLXNA2,HERC5,ABAT,SPATS2L,KIAA1217,USP30,ADSSL1,NUDT12,NOVA1,NUP62CL,EPDR1,GPRIN1,SEC16B,CACNB2,AFF2,RAP2A,NBEA,FBXL2,FIGN,PTPRE,FMNL2,RNF170,CLYBL,NLGN4X,MARS,RABAC1,PAGE5,TBC1D16,FHAD1,GSN,NSD1,ENPP1,GRIK4,GPRC5B,NACC2,L3MBTL4,ENPP6,AKT3,ERN1,MCC,BMP1,PTPRN2,STON2,MMP16,LPP,DOCK9 |
| 4.183e-02 | -3.17 | GO_LATERAL_PLASMA_MEMBRANE | MSigDB lists | GO_LATERAL_PLASMA_MEMBRANE | 48 | 9 | 17377 | 1707 |
EPCAM,ARL2,SCN5A,IQGAP3,BVES,AKAP7,CLDN12,GJB2,DSG2 |
| 4.183e-02 | -3.17 | APRELIKOVA_BRCA1_TARGETS | MSigDB lists | APRELIKOVA_BRCA1_TARGETS | 48 | 9 | 17377 | 1707 |
ID3,CA2,TUBA1A,ACTA2,VIM,TPM1,FGFR1,SFN,WARS |
| 4.183e-02 | -3.17 | ZHU_CMV_8_HR_UP | MSigDB lists | ZHU_CMV_8_HR_UP | 48 | 9 | 17377 | 1707 |
SLC39A14,PLA2G4A,CXCL10,MSX1,CD55,NR4A1,GBP1,MLLT3,WARS |
| 4.183e-02 | -3.17 | MODULE_485 | MSigDB lists | MODULE_485 | 48 | 9 | 17377 | 1707 |
ARL2,SLC40A1,MAP1A,DENND3,GRIK2,MCF2L2,GPR160,CAP2,NT5DC2 |
| 4.183e-02 | -3.17 | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN | MSigDB lists | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_DN | 48 | 9 | 17377 | 1707 |
DZANK1,ZNF395,FRY,AASS,WDR19,STAT5B,DYNC2H1,SESN1,TPT1 |
| 4.183e-02 | -3.17 | GO_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS | 48 | 9 | 17377 | 1707 |
FGFR4,INSIG1,SREBF1,PPARGC1A,DHCR7,GFI1,BMP6,SNAI2,ABCG1 |
| 4.195e-02 | -3.17 | MORF_MAGEA8 | MSigDB lists | MORF_MAGEA8 | 238 | 32 | 17377 | 1707 |
GCA,EHHADH,CFH,WISP3,KLHL23,GABRB2,LRP4,RNF24,RGS7,DOCK3,FAM13A,PRKCA,SLC46A3,FAM110B,COL14A1,TPD52L1,GPR19,PPM1E,ZNF266,ITGBL1,MAP2,ADRB1,COL19A1,PDE4D,ST8SIA1,TANC2,MYT1,NR3C2,SMYD3,NEB,CACNA2D1,B4GALT6 |
| 4.202e-02 | -3.17 | anterior/posterior pattern specification | biological process | GO:0009952 | 199 | 27 | 17256 | 1658 |
EPB41L5,MSX1,CELSR1,BMPR2,WLS,OTX1,PLXNA2,ACVR2B,PGAP1,SKI,DKK1,SMAD3,PCGF2,LRP6,ACVR2A,SEMA3C,HOXD13,BMPR1A,BMP4,HOXB9,COBL,MLLT3,BARX1,SIX2,DDIT3,PCSK6,PCSK5 |
| 4.205e-02 | -3.17 | RABAC1 (Rab acceptor 1) | protein interactions | 10567 | 69 | 12 | 17029 | 1718 |
RPS20,MCF2L,RASD2,SGK1,VIM,RABAC1,RRAS2,SNX10,TSHR,NR3C2,RIMS2,SNCA |
| 4.206e-02 | -3.17 | Signal transduction by L1 | REACTOME pathways | R-HSA-445144 | 21 | 5 | 10287 | 971 |
PAK1,NCAM1,NRP1,FGFR1,ITGB3 |
| 4.206e-02 | -3.17 | TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | REACTOME pathways | R-HSA-6803204 | 21 | 5 | 10287 | 971 |
BBC3,STEAP3,PMAIP1,PRELID1,BNIP3L |
| 4.206e-02 | -3.17 | Signaling by NODAL | REACTOME pathways | R-HSA-1181150 | 21 | 5 | 10287 | 971 |
SMAD3,ACVR2A,ACVR2B,ACVR1C,PCSK6 |
| 4.218e-02 | -3.17 | RGAGGAARY_V$PU1_Q6 | MSigDB lists | RGAGGAARY_V$PU1_Q6 | 471 | 58 | 17377 | 1707 |
PLA2G4A,SEMA6B,LANCL3,CTBP2,CREB5,OVOL2,ITPR2,SEZ6L2,PKN1,FAM81A,LCP2,IKZF2,NAV1,SEC16B,PIK3AP1,STC2,KCNMB3,NCAM1,PTPRCAP,TLR4,VGLL4,TBC1D8,PFKFB4,PCDH10,ITGB7,MSX1,MEIS2,KLHL3,SPATA6,PTPN6,LRMP,PRICKLE1,AGAP2,VIM,SKAP1,HOXA1,SLC7A1,SLC39A14,ATPAF2,ID3,CD37,ICA1,PTPRJ,RPL28,NCKAP1L,SH3RF1,PTK7,EIF4EBP1,CSF1,ALDOA,MAP9,ABI3,INPP5F,SLC1A5,NRP1,NR3C2,FOXA1,PCSK5 |
| 4.236e-02 | -3.16 | INGRAM_SHH_TARGETS_UP | MSigDB lists | INGRAM_SHH_TARGETS_UP | 119 | 18 | 17377 | 1707 |
BDNF,GRB14,NR4A1,DOCK5,RASSF8,ENPP1,IGF1R,FBN1,GPR155,PTK7,CFHR1,KLF9,CMPK2,PLTP,IGFBP3,GLI1,CYP1B1,DUSP1 |
| 4.236e-02 | -3.16 | V$AR_Q2 | MSigDB lists | V$AR_Q2 | 119 | 18 | 17377 | 1707 |
PFKFB4,BDNF,ERGIC1,MSTN,ITGA6,SNAP25,IKZF2,MAP1B,RERE,FOXP2,KCTD15,SEC16B,EIF4EBP1,TMEM86A,PAX9,PPARGC1A,FOXA1,RIMS2 |
| 4.240e-02 | -3.16 | RPL35 (ribosomal protein L35) | protein interactions | 11224 | 124 | 19 | 17029 | 1718 |
RPS20,RPL26,LGALS3,FN1,RPL21,NPM1,LAMC3,AGO4,RPL13A,RPL34,RPL12,RPL28,RPS11,RPL4,RPS12,RPL26L1,SFN,RPS23,RPS13 |
| 4.248e-02 | -3.16 | V$CREBP1CJUN_01 | MSigDB lists | V$CREBP1CJUN_01 | 247 | 33 | 17377 | 1707 |
PHACTR3,CCDC148,AVPI1,ID1,LMCD1,SEZ6L2,CDS1,EEF2,TRPC1,SYNGR3,ARL4D,NCAM1,DUSP1,GLI1,PNRC1,PTPRU,BNIP3L,PNMA6A,SNAP25,MBNL2,RNF44,SPATA7,EBF1,PDLIM3,GNB4,B3GALT2,MAOA,GEM,PPARGC1A,ATG5,HOXB9,MAPK10,PHC1 |
| 4.248e-02 | -3.16 | V$AP1_Q4_01 | MSigDB lists | V$AP1_Q4_01 | 247 | 33 | 17377 | 1707 |
CXCR5,SV2B,PLBD2,SCAMP1,SEC24D,NDRG2,FAM81A,ABHD4,PRR7,PHLDA2,TTC1,TUBB4A,ZNF827,BNIP3,ENO1,SNX10,MARK1,GAPDH,USP2,ESRRG,FGF12,ATP1B1,PRDM1,GNAI1,MAP2,AKT3,C1orf21,ALDOA,DIRAS1,COBL,FRMD5,DDIT3,SFN |
| 4.248e-02 | -3.16 | V$PR_Q2 | MSigDB lists | V$PR_Q2 | 247 | 33 | 17377 | 1707 |
TYRO3,MXI1,BMPR2,JDP2,OTX1,SCD,PPP2R3A,ARHGAP44,HMGCS1,CNTN4,FRY,BACE2,SRGAP1,ACVR2A,BEND4,PDE4D,KCNB2,BDNF,GPM6A,PANK1,JPH1,OBSCN,PALLD,RERE,ITGBL1,MCC,SH3BP4,PGM2L1,DLX2,SEMA3A,FILIP1,RAB30,FOXA1 |
| 4.252e-02 | -3.16 | negative regulation of multicellular organismal process | biological process | GO:0051241 | 1171 | 130 | 17256 | 1658 |
FGF13,LGR4,LDLR,LILRB1,GATA3,NDRG2,STAT5B,ABAT,KREMEN1,SKI,TLR4,SLIT2,PRKACB,NKX2-1,MEIS2,COL4A3,ACVR1C,DCC,LRRK2,F12,SAV1,NCKAP1L,PLK2,ADRB1,SEMA3C,INPP5F,OXTR,DLX2,NRP1,TNFSF4,SPART,MEF2C,EFNB2,FN1,UBASH3B,CHADL,CHSY1,SPINK5,PFN2,FOXG1,EFEMP1,IL17D,SEMA4F,CNTN4,GATA2,MYC,HS3ST5,PRKG1,ADCY6,GPR161,NOS3,PAK1,MSTN,EFNA3,CALCRL,WWC1,MAFB,ADGRB3,THBS4,LAPTM4B,SFMBT1,SEMA3A,ID1,DNM3,NTRK3,PIBF1,CBLN1,SEMA6A,TLR3,BCL6,DAB2IP,PROS1,PDE4D,WWC2,ZNF365,SNAI2,EVL,CSN2,NKX3-2,NLGN4X,RNF125,WNT11,VIM,SYNJ2BP,DOCK5,FGFR1,SMAD3,CXCL10,NRG3,GBP1,PTPRS,HGF,BMPR1A,C1QTNF3,ROBO2,BMPR2,REL,LRP4,HERC5,OVOL2,CUEDC2,GAS6,EPHB1,ADGRB2,RAB11FIP5,NKX6-1,STC2,PRKCD,KIAA0319,FIG4,ERRFI1,YBX3,SMAD6,GFI1,SPRY2,TRPM4,RAPGEF2,PRICKLE1,ZFPM2,TLR6,DKK1,ID3,FBN1,TERT,MCC,BMP4,FOXA1,ATP2B4,DDIT3,TLL2 |
| 4.261e-02 | -3.16 | CCCAGAG,MIR-326 | MSigDB lists | CCCAGAG,MIR-326 | 144 | 21 | 17377 | 1707 |
BCL11B,PXN,CRIM1,CACNA1E,AGPAT4,VLDLR,PLXNA2,ADAMTS6,CEBPA,FNDC3A,PPM1E,KCTD15,RALGPS2,GNAO1,PTK7,RAP2A,KIAA0513,NRP1,SMAD6,PURG,PKIA |
| 4.261e-02 | -3.16 | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN | MSigDB lists | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN | 144 | 21 | 17377 | 1707 |
QSOX1,PCDH18,INPPL1,ID1,BMPR2,GABRB2,LDLR,DUSP9,CBS,ARRDC4,CACHD1,RIMKLB,IGF1R,AKAP7,WFS1,MFSD2A,TOX,JAKMIP3,SUSD4,LIFR,IGSF3 |
| 4.261e-02 | -3.16 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | 144 | 21 | 17377 | 1707 |
AVPI1,ALDH2,SKAP2,TMEM43,MGST3,NFE2L1,FHL2,PKP2,BAIAP2,CYP51A1,TRIB3,ASNS,ICA1,FBN1,EIF4EBP1,SEMA3C,SLC1A5,SNX10,PLTP,RBMS2,DUSP1 |
| 4.265e-02 | -3.15 | regulation of protein complex disassembly | biological process | GO:0043244 | 105 | 16 | 17256 | 1658 |
GSN,PLEKHH2,FGF13,MAP1A,IGF1R,CKAP2,DSTN,EPS8,ADD2,HDGFL3,TMOD2,BNIP3,ASPH,MID1,MAP1B,SCIN |
| 4.268e-02 | -3.15 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_DN | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_DN | 195 | 27 | 17377 | 1707 |
ARHGAP26,EML5,SIDT1,IGFBP6,CRIM1,GALNT6,AGPAT4,PREX1,GSTO1,CHSY1,PHGDH,PLCB1,NEDD4,SYDE2,MKX,KLF12,TDO2,PRKCB,EHD3,PRELID2,DUSP19,NXPH4,IPCEF1,RRAS2,RNF157,PDGFRB,RNF152 |
| 4.274e-02 | -3.15 | eye development | biological process | GO:0001654 | 334 | 42 | 17256 | 1658 |
BCL11B,BMPR2,GATA3,LAMC3,NTRK3,EPHB1,BMP6,SKI,FOXP2,EFEMP1,IRX5,SLC7A11,CHRDL1,TFAP2A,TBC1D32,LRP6,TSPAN12,MYH15,SH3PXD2B,ATP2B1,PDGFRB,CYP1B1,B9D1,RAX,GPM6A,MEIS2,KDM5B,FZD4,SMARCD3,VIM,PRDM1,ACVR2B,SDK1,TSKU,SMAD3,FBN1,WDR19,MYOM2,BMP4,NRP1,NPHP1,ATP2B4 |
| 4.278e-02 | -3.15 | vWFA_dom_sf | interpro domains | IPR036465 | 95 | 15 | 18492 | 1811 |
ANTXR2,COL22A1,ITGB7,CPNE2,CACHD1,COL6A2,SEC24D,MATN2,ITGA2,ITGB3,VWA5A,INTS6,COL14A1,HMCN1,CACNA2D1 |
| 4.278e-02 | -3.15 | C1 | smart domains | SM00109 | 63 | 12 | 9493 | 1056 |
CHN1,VAV3,CHN2,ARHGEF28,PDZD8,UNC13B,PRKCB,PRKCD,PRKCQ,CDC42BPA,PRKCA,RASGRP1 |
| 4.283e-02 | -3.15 | GO_EPIDERMIS_DEVELOPMENT | MSigDB lists | GO_EPIDERMIS_DEVELOPMENT | 221 | 30 | 17377 | 1707 |
EXPH5,PTCH2,BCL11B,INTU,LATS2,CELSR1,EDA2R,LGR4,ST14,SOX21,LRP4,MCOLN3,YAP1,OVOL2,ATOH1,SAV1,PALLD,TNFRSF19,DSP,SATB1,SPINK5,AARS,FGFR1,PLS3,DKK1,GRHL1,PDZD7,KAZN,SFN,GLI1 |
| 4.284e-02 | -3.15 | GO_ACUTE_INFLAMMATORY_RESPONSE | MSigDB lists | GO_ACUTE_INFLAMMATORY_RESPONSE | 71 | 12 | 17377 | 1707 |
CEBPB,ACVR1,MYLK3,FN1,PRCP,ASS1,GATA3,STAT5B,F12,TNFSF4,PTGES,F3 |
| 4.284e-02 | -3.15 | GO_CELLULAR_RESPONSE_TO_CARBOHYDRATE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_CARBOHYDRATE_STIMULUS | 71 | 12 | 17377 | 1707 |
IRS2,RAB11FIP5,RPS6KA2,FN1,PRKCB,MAP2K6,XBP1,ERN1,CALCRL,PTPRN2,GAS6,PPARGC1A |
| 4.292e-02 | -3.15 | PLD1 (phospholipase D1) | protein interactions | 5337 | 47 | 9 | 17029 | 1718 |
PKN3,OSBPL5,PLD1,PRKCA,PKN1,APBA2,TNFRSF19,STXBP1,SNCA |
| 4.297e-02 | -3.15 | MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_5_6WK_UP | 111 | 17 | 17377 | 1707 |
EHHADH,CSN2,STXBP6,CYP4V2,PKP2,ATP1B1,TSPAN17,SFXN1,RND3,BCHE,GRHL1,DSG2,PAM,PCOLCE2,NIPAL2,OCLN,TMEM56 |
| 4.301e-02 | -3.15 | GSE25087_FETAL_VS_ADULT_TCONV_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TCONV_UP | 178 | 25 | 17377 | 1707 |
PAK1,FADS1,ATF4,GAPDH,PLEKHA5,LPCAT2,TMTC4,PHACTR2,ADAMTS6,CHAC1,ITPR2,ATP1B1,COTL1,IKZF2,MAGI3,AHRR,ZNF711,ZNF827,TIFA,EIF4EBP1,SLC7A5,PLEKHG1,PIK3C2B,FAR2,MBOAT2 |
| 4.301e-02 | -3.15 | PRC2_EED_UP.V1_UP | MSigDB lists | PRC2_EED_UP.V1_UP | 178 | 25 | 17377 | 1707 |
SERINC5,PCSK1N,PLSCR4,DUSP8,CLGN,ZHX3,PRSS12,PLAG1,OBSCN,ATF3,SATB1,TRPS1,GPR37,GALNT3,CXCL10,PMEPA1,C1orf21,TUFT1,SLC6A15,TSPAN13,ZBTB20,MPDZ,TNFRSF11A,NR3C2,KIF1B |
| 4.301e-02 | -3.15 | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MONOCYTE_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MONOCYTE_UP | 178 | 25 | 17377 | 1707 |
IL15,TMEM43,SPATA6,NLGN4X,F12,STK24,FHOD3,ZIC1,QPRT,RASSF8,LGI2,POPDC3,PDZD8,PAIP2B,RPS11,TECPR2,DYNC2LI1,TFAP2A,TSPAN12,BNIP3,UNC5B,RAB27B,CHRM3,ATP1A3,ZNF391 |
| 4.301e-02 | -3.15 | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_UP | 178 | 25 | 17377 | 1707 |
TFCP2L1,ZNF516,AVPI1,PDK1,PNRC1,RNF144A,GALNT12,TGFA,ITGA6,SELL,RASA3,LAMC3,ARHGAP32,KBTBD11,ASPH,PLEKHB1,MAP2K6,HGF,NAP1L3,RPS12,FHIT,NCAM1,SUSD4,APBA2,ACSM3 |
| 4.302e-02 | -3.15 | GO_REGULATION_OF_PROTEIN_POLYMERIZATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_POLYMERIZATION | 161 | 23 | 17377 | 1707 |
FER,EVL,EPS8,PREX1,ADD2,ARL2,PFN2,PPP1R9A,SPIRE1,FHOD3,BAIAP2,SCIN,SNCA,GSN,MYADM,NCKAP1L,WIPF3,PRKCD,SGK1,TMOD2,CTTN,SLIT2,FES |
| 4.302e-02 | -3.15 | WNT_UP.V1_DN | MSigDB lists | WNT_UP.V1_DN | 161 | 23 | 17377 | 1707 |
EFNB2,IGFBP6,SH2D2A,FOXN3,BIK,GABRG2,RASD1,VIM,TLR6,SERGEF,NT5DC2,NEO1,PCDH7,TGFBR3,SLC22A18,CFHR1,ATP7B,ADRB1,MET,CMPK2,OCLN,CNTN1,HEY1 |
| 4.303e-02 | -3.15 | FERM_PH-like_C | interpro domains | IPR018980 | 27 | 6 | 18492 | 1811 |
EPB41L5,EPB41L3,FARP1,PTPN13,FRMD5,PTPN21 |
| 4.303e-02 | -3.15 | K_chnl_volt-dep_Kv | interpro domains | IPR003968 | 27 | 6 | 18492 | 1811 |
KCNV1,KCND3,KCNC4,KCNG1,KCNB2,KCNS3 |
| 4.328e-02 | -3.14 | LRCH3 (leucine rich repeats and calponin homology domain containing 3) | protein interactions | 84859 | 33 | 7 | 17029 | 1718 |
MOB1B,DBN1,SUGT1,DOCK7,TPM1,DOCK6,DOCK8 |
| 4.328e-02 | -3.14 | FRS2 (fibroblast growth factor receptor substrate 2) | protein interactions | 10818 | 33 | 7 | 17029 | 1718 |
PAK1,NTRK3,SORBS1,DDR1,SPRY2,FGFR1,GAB2 |
| 4.328e-02 | -3.14 | response to corticosteroid | biological process | GO:0031960 | 156 | 22 | 17256 | 1658 |
MSTN,PTPRU,ASS1,NTRK3,ABCC2,BMP6,DDIT4,FBXO32,BCHE,EIF4EBP1,CTSV,PAM,KLF9,ERRFI1,PCK2,AGL,SMYD3,SLIT2,ZFP36L2,ATP2B1,DUSP1,HEY1 |
| 4.328e-02 | -3.14 | fatty acid derivative metabolic process | biological process | GO:1901568 | 156 | 22 | 17256 | 1658 |
PLA2G4A,FADS1,ACSL1,ALOX5AP,CYP2J2,MGST3,ELOVL7,ELOVL3,FASN,HACD1,SCD,DAGLA,MAPKAPK2,FAAH2,BDH2,TNFRSF1A,HPGD,CYP2U1,FAR2,SYK,PTGES,CYP1B1 |
| 4.333e-02 | -3.14 | - | gene3d domains | 2.120.10.30 | 38 | 8 | 8148 | 867 |
TENM1,TRIM2,LRP4,VLDLR,LDLR,PAM,LRP6,TRIM3 |
| 4.336e-02 | -3.14 | central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-oligoastrocytoma_Grade_III | 120 | 18 | 17385 | 1698 |
ACVR1,RNF145,SMAD9,CELSR1,EHHADH,FAM131C,SYT12,OGDHL,OBSCN,ADAMTS6,GPC6,FRY,PDZD8,EDA,POU5F1B,SP140,MYO6,TLL2 |
| 4.337e-02 | -3.14 | Lipoprotein metabolism | REACTOME pathways | R-HSA-174824 | 74 | 12 | 10287 | 971 |
SOAT2,VLDLR,LDLR,BMP1,NPC2,NCEH1,PLTP,PRKACB,ABCG1,PCSK5,CES3,PCSK6 |
| 4.342e-02 | -3.14 | GO_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_GLUTAMATE_RECEPTOR_SIGNALING_PATHWAY | 41 | 8 | 17377 | 1707 |
GRIK4,GRIK2,HOMER2,GRID1,GRIN2D,PLCB1,HOMER3,ATP1A3 |
| 4.342e-02 | -3.14 | NAKAYAMA_FRA2_TARGETS | MSigDB lists | NAKAYAMA_FRA2_TARGETS | 41 | 8 | 17377 | 1707 |
CHN1,FBXO32,LGR4,CKAP2,BCL6,SGK1,CTTN,DBP |
| 4.342e-02 | -3.14 | GO_RESPONSE_TO_COLD | MSigDB lists | GO_RESPONSE_TO_COLD | 41 | 8 | 17377 | 1707 |
CXCL10,PCSK1N,ZNF516,DNAJC3,ADRB1,PPARGC1A,HSPA2,ATP2B1 |
| 4.342e-02 | -3.14 | PID_BMP_PATHWAY | MSigDB lists | PID_BMP_PATHWAY | 41 | 8 | 17377 | 1707 |
SMAD9,BMPR2,CHRDL1,BMP4,BMPR1A,SMAD6,BMP6,SKI |
| 4.350e-02 | -3.13 | MODULE_544 | MSigDB lists | MODULE_544 | 79 | 13 | 17377 | 1707 |
TLR3,LGR4,GRB14,BACE2,SLC36A1,CFHR1,SEMA3C,F12,CDH2,THSD1,IL1RAP,PPP2R3A,CACNA2D1 |
| 4.350e-02 | -3.13 | RYAAAKNNNNNNTTGW_UNKNOWN | MSigDB lists | RYAAAKNNNNNNTTGW_UNKNOWN | 79 | 13 | 17377 | 1707 |
NKX6-1,FOXP2,ABLIM1,GPM6A,CHCHD7,GRIK2,AKT3,PLAG1,NKX2-8,NOVA1,PPP2R3A,ZIC1,TRPS1 |
| 4.350e-02 | -3.13 | KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY | MSigDB lists | KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY | 79 | 13 | 17377 | 1707 |
PLA2G4A,VAV3,PRKCB,MAP2K6,AKT3,PRKCD,MAPK13,PRKCA,LCP2,MAPK10,RAC3,SYK,GAB2 |
| 4.356e-02 | -3.13 | DCLK1 (doublecortin like kinase 1) | protein interactions | 9201 | 77 | 13 | 17029 | 1718 |
CGN,PHLDB2,NAV1,LCA5,RASAL2,PLEKHA5,SH3BP4,MAP3K21,CBY1,LPIN3,FAM110B,LARP1,GAB2 |
| 4.356e-02 | -3.13 | CSK (C-terminal Src kinase) | protein interactions | 1445 | 77 | 13 | 17029 | 1718 |
ID3,GSN,TNK2,RGS16,FGR,PXN,TLR3,IGF1R,UBASH3B,FHL2,SDC3,TNS1,FRK |
| 4.357e-02 | -3.13 | BIOCARTA_EDG1_PATHWAY | MSigDB lists | BIOCARTA_EDG1_PATHWAY | 27 | 6 | 17377 | 1707 |
PRKCA,PRKCB,PLCB1,ITGB3,GNAI1,ADCY1 |
| 4.357e-02 | -3.13 | GO_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MESENCHYMAL_CELL_PROLIFERATION | 27 | 6 | 17377 | 1707 |
IRS2,FOXP2,BMPR1A,SHOX2,MYC,FGFR1 |
| 4.357e-02 | -3.13 | MAYBURD_RESPONSE_TO_L663536_UP | MSigDB lists | MAYBURD_RESPONSE_TO_L663536_UP | 27 | 6 | 17377 | 1707 |
ARHGAP26,SEMA6B,GARS,SLC7A11,IL1RAP,WDR19 |
| 4.357e-02 | -3.13 | GO_MOTOR_NEURON_AXON_GUIDANCE | MSigDB lists | GO_MOTOR_NEURON_AXON_GUIDANCE | 27 | 6 | 17377 | 1707 |
KIF5C,CHN1,NRP1,SEMA3A,SLIT2,PLXNA2 |
| 4.357e-02 | -3.13 | GROSS_ELK3_TARGETS_UP | MSigDB lists | GROSS_ELK3_TARGETS_UP | 27 | 6 | 17377 | 1707 |
ASS1,TCF7L1,BMP4,RRAS2,CPE,ABCG1 |
| 4.357e-02 | -3.13 | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | MSigDB lists | WATANABE_COLON_CANCER_MSI_VS_MSS_UP | 27 | 6 | 17377 | 1707 |
PLA2G4A,ZIC2,IQGAP3,RAB27B,PDE10A,TFAP2A |
| 4.357e-02 | -3.13 | GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | MSigDB lists | GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | 27 | 6 | 17377 | 1707 |
BBC3,BNIP3,HRK,PMAIP1,FAM162A,BIK |
| 4.357e-02 | -3.13 | GO_VENTRICULAR_SEPTUM_MORPHOGENESIS | MSigDB lists | GO_VENTRICULAR_SEPTUM_MORPHOGENESIS | 27 | 6 | 17377 | 1707 |
WNT11,ZFPM2,SAV1,HEYL,HEY1,FZD1 |
| 4.357e-02 | -3.13 | GO_RESPONSE_TO_ISCHEMIA | MSigDB lists | GO_RESPONSE_TO_ISCHEMIA | 27 | 6 | 17377 | 1707 |
FN1,EEF2,PPARGC1A,MAP2K6,EIF4EBP1,HK2 |
| 4.357e-02 | -3.13 | SAKAI_TUMOR_INFILTRATING_MONOCYTES_UP | MSigDB lists | SAKAI_TUMOR_INFILTRATING_MONOCYTES_UP | 27 | 6 | 17377 | 1707 |
WASF3,CDC42BPA,SH3GL2,CACNB4,BTRC,ITGB3 |
| 4.357e-02 | -3.13 | GO_POSITIVE_REGULATION_OF_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_PHOSPHATASE_ACTIVITY | 27 | 6 | 17377 | 1707 |
SMAD3,MAGI2,ITGA2,PDGFRB,GPLD1,MEF2C |
| 4.357e-02 | -3.13 | GO_NEGATIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | 27 | 6 | 17377 | 1707 |
DAB2IP,PMAIP1,MYC,B4GALT7,C1QL4,SKI |
| 4.358e-02 | -3.13 | adenyl ribonucleotide binding | molecular function | GO:0032559 | 1502 | 166 | 17224 | 1680 |
NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,ASS1,PRKCA,AARS,STK24,MOK,RPS6KA2,DNAH6,CNNM2,EPHB6,PRKACB,PDGFRB,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,PIK3C2B,DNHD1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,BVES,SCN8A,SLK,RIMKLA,CHD5,HSPA12B,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,MYO10,SLC27A2,RAPGEF4,OBSCN,STRADB,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,HK2,SLFN5,PANK3,ACSM3,EPHA3,NEK10,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,MET,DNAH5,HSPA2,FER,GARS,MYLK3,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,PTK7,MAP3K21,BMPR1A,MAPK10,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,NLRP14,KIF5C,P2RY1,PKN1,EPHB1,PRKCD,EHD3,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,MYO6,SYK,ATP2B1,FES,PFKFB4,TRPM4,OPLAH,RAPGEF2,NUAK2,AK4,MARS,ATP11A,PEAK1,TRIB3,FGR,AKT3,MAP2K6,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,CMPK2,MAP3K20,KIF1B,ATP2B4,ABCG1,ATP1A3 |
| 4.361e-02 | -3.13 | MAPK12 (mitogen-activated protein kinase 12) | protein interactions | 6300 | 40 | 8 | 17029 | 1718 |
MYLK3,MAP2K6,DLG2,MAPK13,SNTB1,PKN1,DUSP1,PATJ |
| 4.361e-02 | -3.13 | Itgb1 (integrin beta 1 (fibronectin receptor beta)) | protein interactions | 16412 | 40 | 8 | 17029 | 1718 |
FAT1,ITGA6,ITGA2,UBAC2,SLC1A5,CANX,ATP2B1,CACNA2D1 |
| 4.361e-02 | -3.13 | GPX4 (glutathione peroxidase 4) | protein interactions | 2879 | 40 | 8 | 17029 | 1718 |
MAPK13,ENO2,UCHL3,GSTO2,ERO1B,ENO1,ALDOC,ALDOA |
| 4.362e-02 | -3.13 | GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_DN | MSigDB lists | GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_DN | 136 | 20 | 17377 | 1707 |
SEMA6B,RNF144A,PTPRD,DNAJC6,ADCY1,SPATA13,RASL11B,PHACTR2,TNKS1BP1,NEDD4,HERPUD1,CDR2L,ZFYVE28,EIF4EBP1,EBF4,HGF,SNX10,KCTD1,GAB2,PNMA2 |
| 4.362e-02 | -3.13 | KVCHANNEL | prints domains | PR01491 | 27 | 6 | 4652 | 458 |
KCNV1,KCND3,KCNC4,KCNG1,KCNB2,KCNS3 |
| 4.373e-02 | -3.13 | GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 95 | 15 | 17377 | 1707 |
SMAD3,CGN,ACVR1,GCNT2,TGFBR3,PXN,ID1,SMAD9,MSTN,FERMT2,HPGD,BMPR1A,SMAD6,ZFYVE9,SKI |
| 4.373e-02 | -3.13 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | 95 | 15 | 17377 | 1707 |
CRIM1,GCAT,GBP1,DSTN,EPS8,RAP2A,RGS20,NPM1,SPATS2L,COTL1,SPRY2,ATP10D,PRKACB,PLS3,DKK1 |
| 4.377e-02 | -3.13 | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | MSigDB lists | NEMETH_INFLAMMATORY_RESPONSE_LPS_UP | 87 | 14 | 17377 | 1707 |
MAPKAPK2,RGS16,MYADM,PNP,KPNA3,MYO10,PRKCD,EIF1,MSR1,BCL6B,ATF3,LCP2,CEBPD,HMGCR |
| 4.383e-02 | -3.13 | Regulation of lipolysis in adipocytes | KEGG pathways | hsa04923 | 54 | 10 | 7161 | 730 |
IRS2,AKT3,PRKG1,ADCY1,ADRB1,ADCY6,PRKG2,TSHR,PRKACB,GNAI1 |
| 4.406e-02 | -3.12 | regulation of mast cell activation | biological process | GO:0033003 | 42 | 8 | 17256 | 1658 |
FER,FGR,GATA2,STXBP1,SYK,VAMP8,FES,GAB2 |
| 4.406e-02 | -3.12 | receptor clustering | biological process | GO:0043113 | 42 | 8 | 17256 | 1658 |
ITGB7,GRIK2,WDR19,LRP4,DLG2,NRXN1,CDH2,MAGI2 |
| 4.406e-02 | -3.12 | regulation of protein autophosphorylation | biological process | GO:0031952 | 42 | 8 | 17256 | 1658 |
VEGFC,MOB1B,ENPP1,NEK10,ERRFI1,TNKS1BP1,SYK,RAP2A |
| 4.406e-02 | -3.12 | neuromuscular junction development | biological process | GO:0007528 | 42 | 8 | 17256 | 1658 |
UNC13B,CACNB2,SHANK2,LRRK2,LRP4,COL4A5,CACNB4,NEDD4 |
| 4.408e-02 | -3.12 | GSE25087_FETAL_VS_ADULT_TREG_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_UP | 187 | 26 | 17377 | 1707 |
FARP1,ATF4,KDM5B,BTNL9,KLHL23,NPM3,PLAG1,LRP4,DHCR24,BATF,NDFIP2,CANX,ILDR2,ZNF827,TMEM237,RALGPS2,SLC7A11,DACT1,GNB4,TOX,CTTN,CMPK2,RRAS2,ESD,HEY1,LAMP3 |
| 4.408e-02 | -3.12 | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP | 187 | 26 | 17377 | 1707 |
UST,PFKFB4,EFNB2,FGFR4,THOC5,SLC27A2,KLHL23,AK4,WNT11,ACVR2B,GPSM2,GRK6,CACNB4,DKK1,IRS2,PDLIM3,IGF1R,NOVA2,BBC3,NXPH4,TPM1,RAB27B,ZNF460,SEMA6C,IGSF3,ZNF391 |
| 4.408e-02 | -3.12 | VEGF_A_UP.V1_UP | MSigDB lists | VEGF_A_UP.V1_UP | 187 | 26 | 17377 | 1707 |
MN1,SH3BP2,IL32,ENO2,DUSP8,GRIK2,AKAP5,ZCCHC24,ATF3,DENND3,DDIT4,ISG20,PTPRC,IRS2,DYRK1B,IQCK,PTPRJ,FMO4,DSG2,MATN2,DLG2,PLTP,SPOCK3,DDIT3,TLL2,GLI1 |
| 4.408e-02 | -3.12 | GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP | 187 | 26 | 17377 | 1707 |
TRDMT1,DPYSL5,MOCOS,INPPL1,GCNT2,PHLDA2,CA13,CCNJ,TTC1,RASSF8,ENTPD1,TMCO3,PMEPA1,FBN1,MARVELD2,RASD2,ALDH1L1,CCNA1,EEPD1,RNF130,CTTN,ST8SIA1,RRAS2,RBMS2,SMPDL3A,ZNF385A |
| 4.408e-02 | -3.12 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN | 187 | 26 | 17377 | 1707 |
EXPH5,FARP1,GARS,ABCC4,SH2D2A,UBASH3B,LITAF,FHL2,PRICKLE1,TUBE1,FAM81A,DSP,CA13,EPDR1,ICA1,SH3RF1,GTSF1,GNB4,PRELID2,SMTN,TUFT1,BEND4,IQGAP3,MMP16,RAPGEF5,STOM |
| 4.408e-02 | -3.12 | GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_DN | MSigDB lists | GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_DN | 187 | 26 | 17377 | 1707 |
CREB3L2,ITGB7,UGT8,EVL,GCNT2,MYLK3,SH2D2A,SEC24D,ADM2,SLC39A8,TES,ARL15,CHADL,SHISA2,PRDM1,STK24,GABARAPL1,TECPR1,OR2T33,ABI3,ITGB3,HS3ST3B1,ATG5,TESC,ATP2B1,GLDC |
| 4.408e-02 | -3.12 | GSE360_L_DONOVANI_VS_T_GONDII_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_DC_DN | 187 | 26 | 17377 | 1707 |
ARHGAP26,FADS1,ID1,CACNG3,ANK2,TGFA,NHP2,KBTBD11,CTIF,GJC1,BCL11A,SLC7A1,HMGCS1,MAP1A,IGF1R,CHRNA5,ALDOC,C1orf21,SQLE,TNFSF4,DHCR7,TSPAN9,MMP16,GPR161,IGSF3,LAMP3 |
| 4.408e-02 | -3.12 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN | 187 | 26 | 17377 | 1707 |
DMXL2,ACSL1,PXN,TTC39B,PSTPIP2,AGPAT4,DEPTOR,MRPL22,SCD,LCP2,PRKCA,TTC30B,ID3,FAM168A,ALDOC,ABI3,STARD4,TSC22D1,MYO6,TBC1D9,PLTP,LRRC27,SNX10,SYK,DCBLD1,TBC1D8 |
| 4.408e-02 | -3.12 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP | 187 | 26 | 17377 | 1707 |
EVL,RASAL2,TRIM16,CRIM1,TGFA,MYO1B,MGAT4B,DHCR24,ACO1,NFE2L1,SLC1A3,ABHD4,CLN5,SLC7A11,MSMO1,ABCA5,PAM,OPN3,P4HA1,MAOA,GSTM3,STEAP3,NRP1,LRP12,LAMP3,LPP |
| 4.408e-02 | -3.12 | GSE6875_TCONV_VS_FOXP3_KO_TREG_DN | MSigDB lists | GSE6875_TCONV_VS_FOXP3_KO_TREG_DN | 187 | 26 | 17377 | 1707 |
UROS,RHOBTB1,TDRD3,ATP8A1,PPFIBP2,TMTC4,SPATA13,SLC36A4,CHSY1,TGDS,CACNB4,TPD52L1,FGFR1,TRPS1,ZFYVE28,WFS1,ERN1,SRGAP1,NBEA,FAM149A,DSEL,MARCKS,PLD1,FHIT,SMAD6,CEBPD |
| 4.408e-02 | -3.12 | GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_UP | MSigDB lists | GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_UP | 187 | 26 | 17377 | 1707 |
PAK1,ALDH2,SCAMP1,RAB6B,RECK,PANK1,CRIP2,CALCRL,NDRG2,KCTD12,ATP1B1,CRYBG3,FGFR1,ARHGAP21,GALNT1,TECPR1,ABI3BP,STARD4,RCN3,PTPRS,TMEM37,MED7,PLD1,ETV1,TSPAN9,CTNND2 |
| 4.408e-02 | -3.12 | GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 187 | 26 | 17377 | 1707 |
LONRF1,SV2B,LPAR2,MYLK3,SCN8A,GTF2IRD1,PSD3,RAB38,TXNRD3,IFT81,CPNE2,PKN3,MGAT1,PRCP,LRRIQ3,DSEL,KIF21A,DYNC2H1,TNFRSF17,TBC1D9,SLC1A5,THSD1,FMNL2,CTNND2,CKAP4,BTRC |
| 4.408e-02 | -3.12 | GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_UP | MSigDB lists | GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_UP | 187 | 26 | 17377 | 1707 |
ZSWIM5,GCNT2,PNP,HNF4G,NKX3-2,CHAC1,LPIN3,CHD5,DACH2,GPC6,PTPRC,DEXI,HMGCS1,RNF217,LRRC6,PIK3AP1,EHD3,DYNC2LI1,SREBF1,CPXM2,ARHGAP28,BEND4,PAX9,IPCEF1,GLIS1,CTH |
| 4.413e-02 | -3.12 | GTP binding | molecular function | GO:0005525 | 366 | 46 | 17224 | 1680 |
MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,RAP2A,RASD2,EHD3,RAB26,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD |
| 4.415e-02 | -3.12 | regulation of calcium ion transmembrane transporter activity | biological process | GO:1901019 | 89 | 14 | 17256 | 1658 |
GSTM2,CACNB2,ANK2,JPH1,EHD3,RYR2,GSTO1,ATP1B1,PDE4D,GEM,CACNB4,HSPA2,CACNA2D1,NOS1AP |
| 4.415e-02 | -3.12 | axis specification | biological process | GO:0009798 | 89 | 14 | 17256 | 1658 |
EPB41L5,SETDB2,WLS,LRP4,LRP6,BMPR1A,BMP4,SMAD6,COBL,PGAP1,SIX2,DDIT3,PCSK6,SKI |
| 4.415e-02 | -3.12 | negative regulation of cell morphogenesis involved in differentiation | biological process | GO:0010771 | 89 | 14 | 17256 | 1658 |
DNM3,ID1,FGF13,SEMA4F,DCC,GBP1,RAPGEF2,LRP4,PTPRS,SEMA3C,SPART,NRP1,SEMA3A,SLIT2 |
| 4.421e-02 | -3.12 | BTB/POZ_dom | interpro domains | IPR000210 | 179 | 25 | 18492 | 1811 |
KCNV1,RHOBTB1,KLHL3,KLHL13,KLHL23,KLHL4,BCL6B,KCTD12,BTBD9,KCND3,KBTBD11,KCNC4,KCTD15,ZBTB38,BACH2,NACC2,KCNG1,GAN,BCL6,KCNS3,ZBTB20,KLHL31,KLHL29,KCTD1,KCNB2 |
| 4.421e-02 | -3.12 | JIANG_AGING_CEREBRAL_CORTEX_UP | MSigDB lists | JIANG_AGING_CEREBRAL_CORTEX_UP | 34 | 7 | 17377 | 1707 |
VIM,CCNG1,MARCKS,COL6A2,CPE,EIF1,TPT1 |
| 4.421e-02 | -3.12 | chr1p33 | MSigDB lists | chr1p33 | 34 | 7 | 17377 | 1707 |
TGFBR3,SLC6A9,RCAN3,TTC39A,COL9A2,ZFYVE9,DHCR24 |
| 4.421e-02 | -3.12 | chr8q13 | MSigDB lists | chr8q13 | 34 | 7 | 17377 | 1707 |
SLCO5A1,GDAP1,MSC,XKR9,GEM,TCF24,KCNB2 |
| 4.421e-02 | -3.12 | GO_BETA_AMYLOID_BINDING | MSigDB lists | GO_BETA_AMYLOID_BINDING | 34 | 7 | 17377 | 1707 |
APBA1,APBA2,BCHE,BACE2,COL25A1,BACE1,APBB1 |
| 4.421e-02 | -3.12 | GO_LUNG_EPITHELIUM_DEVELOPMENT | MSigDB lists | GO_LUNG_EPITHELIUM_DEVELOPMENT | 34 | 7 | 17377 | 1707 |
YAP1,BMP4,GPSM2,SAV1,ERRFI1,FOXA1,NKX2-1 |
| 4.421e-02 | -3.12 | REACTOME_SIGNAL_TRANSDUCTION_BY_L1 | MSigDB lists | REACTOME_SIGNAL_TRANSDUCTION_BY_L1 | 34 | 7 | 17377 | 1707 |
PAK1,RPS6KA2,SH3GL2,NCAM1,NRP1,FGFR1,ITGB3 |
| 4.421e-02 | -3.12 | GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | MSigDB lists | GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT | 34 | 7 | 17377 | 1707 |
ACTA2,BMP4,LGR4,MAGI2,SIX2,POU3F3,MEF2C |
| 4.421e-02 | -3.12 | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN | MSigDB lists | DACOSTA_ERCC3_ALLELE_XPCS_VS_TTD_DN | 34 | 7 | 17377 | 1707 |
GULP1,ROR1,BMP4,DOK5,PPP2R3A,CAND2,VLDLR |
| 4.421e-02 | -3.12 | MODY_HIPPOCAMPUS_NEONATAL | MSigDB lists | MODY_HIPPOCAMPUS_NEONATAL | 34 | 7 | 17377 | 1707 |
SQLE,TUBA1A,NCAM1,NRP1,FN1,CDH2,FASN |
| 4.421e-02 | -3.12 | WANG_METHYLATED_IN_BREAST_CANCER | MSigDB lists | WANG_METHYLATED_IN_BREAST_CANCER | 34 | 7 | 17377 | 1707 |
IRS2,SLC3A2,MYO1B,SLC7A5,F3,DKK1,DUSP1 |
| 4.421e-02 | -3.12 | MH1 | prosite domains | PS51075 | 8 | 3 | 12060 | 1278 |
SMAD3,SMAD9,SMAD6 |
| 4.421e-02 | -3.12 | GATA_ZN_FINGER_1 | prosite domains | PS00344 | 8 | 3 | 12060 | 1278 |
GATA3,GATA2,TRPS1 |
| 4.421e-02 | -3.12 | MH2 | prosite domains | PS51076 | 8 | 3 | 12060 | 1278 |
SMAD3,SMAD9,SMAD6 |
| 4.422e-02 | -3.12 | GO_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_PASSIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 445 | 55 | 17377 | 1707 |
KCNV1,ANO10,TMEM63C,SCN5A,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,GABRR2,ITPR2,GAS6,KCNC4,CACNB4,NCS1,MCU,MCOLN2,KCNJ4,KCNN2,KCNAB1,CHRNA5,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,KCNH5,GJB2,CACNA1E,GRID1,TTYH2,RYR2,RASA3,CHRNA6,KCND3,STEAP1,GJC1,GRIK4,KCNK15,KCNMB4,KCNG1,GRIN2D,TRPC3,CACNA2D1,DENND5B |
| 4.422e-02 | -3.12 | PKCA_DN.V1_DN | MSigDB lists | PKCA_DN.V1_DN | 153 | 22 | 17377 | 1707 |
ITGB7,EIF4E3,CFH,SYT12,MYO1B,FAM198B,PRKCA,BATF3,PYCR1,MSC,TIFA,ABI3BP,COL25A1,GBP1,FABP6,HK2,SHF,SEMA6C,CKAP4,PDGFRB,NKX2-1,GLDC |
| 4.422e-02 | -3.12 | HALLMARK_UV_RESPONSE_UP | MSigDB lists | HALLMARK_UV_RESPONSE_UP | 153 | 22 | 17377 | 1707 |
TYRO3,MSX1,ENO2,PTPRD,NR4A1,NTRK3,ATF3,C4BPB,EPCAM,HTR7,ASNS,CA2,PDLIM3,CHRNA5,MGAT1,PRKCD,ALDOA,MAOA,NPTXR,SHOX2,HSPA2,RASGRP1 |
| 4.423e-02 | -3.12 | Sterol Regulatory Element-Binding Proteins (SREBP) signalling | WikiPathways | WP1982 | 73 | 13 | 5312 | 569 |
PRKAA2,CYP51A1,IDI1,HMGCS1,INSIG1,SEC24D,MVD,LDLR,FASN,SREBF1,SQLE,SCD,HMGCR |
| 4.429e-02 | -3.12 | skin-face-malignant_melanoma | COSMIC cancer mutations | skin-face-malignant_melanoma | 137 | 20 | 17385 | 1698 |
FER,CACNG3,PTPRD,DCC,PTPN13,PTPN21,TNS1,EPHB1,KHDRBS2,PTPRC,TMEM132B,PTPRJ,ADAMTS3,ZNF214,PTK7,PTPRS,PTPRN2,MET,PTPRE,CHRM3 |
| 4.429e-02 | -3.12 | Differentiation of white and brown adipocyte | WikiPathways | WP2895 | 25 | 6 | 5312 | 569 |
CEBPB,CEBPA,BMP4,PPARGC1A,SMAD9,ZIC1 |
| 4.430e-02 | -3.12 | IQ | prosite domains | PS50096 | 81 | 14 | 12060 | 1278 |
MYO1D,IQCH,LRRIQ1,MYO10,SCN8A,RASGRF2,LRRIQ3,MYO1B,MYO3B,OBSCN,IQGAP3,IQSEC2,SCN2A,SCN3A |
| 4.432e-02 | -3.12 | TMEM30A (transmembrane protein 30A) | protein interactions | 55754 | 62 | 11 | 17029 | 1718 |
TMEM67,CHRNA5,BACE2,ATP8A1,ADGRL1,BNIP3,ACVR2B,ATP11A,NRP1,GPC6,HMGCR |
| 4.433e-02 | -3.12 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN | 170 | 24 | 17377 | 1707 |
GCA,SLC40A1,CHCHD7,KLHL3,PTPN6,PPFIBP2,TCEA3,RASA3,FAM117B,CBY1,TEX9,SFXN1,CACHD1,RSL24D1,LMLN,TECPR1,KCNMB4,KIAA0895,FMO4,AFF2,ALPK1,FHIT,GATM,ZNF391 |
| 4.433e-02 | -3.12 | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_DN | 170 | 24 | 17377 | 1707 |
GPT2,NECAB2,EHHADH,AASS,CYP2J2,MYO1B,SYBU,OGDHL,COL18A1,ABAT,F12,SLC46A3,AMDHD1,LDHD,GPLD1,CDC14B,SLC16A2,FMO4,ALDH1L1,RUNDC3B,MPDZ,KLF9,MYRIP,CTH |
| 4.433e-02 | -3.12 | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DN | 170 | 24 | 17377 | 1707 |
MYCBP2,RPL26,KLHL13,NFIA,SYNJ2BP,FAM198B,NOVA1,MBNL2,SPATA7,HECTD2,TMEM74,NAV1,KCNN2,SLC22A17,MAP1A,PLOD2,CLDN12,EMILIN2,PRELID1,FHIT,ESD,MMP16,PRKACB,CTNND2 |
| 4.433e-02 | -3.12 | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP | MSigDB lists | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP | 170 | 24 | 17377 | 1707 |
PDLIM7,MYO1D,INPPL1,EVL,PXN,TCP11L2,KDM5B,BMPR2,PTPN6,COBLL1,SLC12A6,PFN2,SLC46A3,SPNS1,ABLIM1,IKZF3,GNAO1,SGK1,TMEM132E,CMPK2,RNF122,DOCK8,GAB2,MEF2C |
| 4.433e-02 | -3.12 | regulation of mitochondrial membrane potential | biological process | GO:0051881 | 65 | 11 | 17256 | 1658 |
PRKN,ATP5IF1,PMAIP1,LRRK2,PRELID1,BNIP3L,SLC25A27,BNIP3,RACK1,SPART,PYCR1 |
| 4.437e-02 | -3.12 | BIOCARTA_PPARA_PATHWAY | MSigDB lists | BIOCARTA_PPARA_PATHWAY | 56 | 10 | 17377 | 1707 |
EHHADH,PRKCB,FAT1,MYC,PRKAR2B,STAT5B,PRKCA,PPARGC1A,PRKACB,DUSP1 |
| 4.437e-02 | -3.12 | chr15q26 | MSigDB lists | chr15q26 | 56 | 10 | 17377 | 1707 |
SV2B,IGF1R,MCTP2,LRRK1,ARRDC4,FAM174B,SLCO3A1,FES,ISG20,PCSK6 |
| 4.437e-02 | -3.12 | GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | MSigDB lists | GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE | 56 | 10 | 17377 | 1707 |
TRPM4,TLR3,GPRC5B,BCL6,LILRB1,GATA3,CUEDC2,ATG5,TNFSF4,TLR4 |
| 4.439e-02 | -3.11 | whole membrane | cellular component | GO:0098805 | 1629 | 174 | 18223 | 1724 |
DOC2A,ACSL1,CACNG3,ATP8A1,SYT12,LDLR,MCOLN3,VAMP8,ASS1,ITPR2,SLC9A7,NOS1AP,PCDH7,RND2,TM9SF2,SEC16B,PMAIP1,ZFYVE28,ITGB3,RAP2A,RAB26,PPP2R2B,TLR4,CPE,LAMP3,GDAP1,CD55,ABCC4,ANK2,WLS,TGFA,LRRK2,LRMP,BNIP3L,PRKAR2B,GNAI1,SPNS1,ENPP1,TMEM150B,HPSE,NCKAP1L,ENTPD7,GNB4,TNFRSF1A,INPP5F,UNC5B,SPART,RRAGD,CHMP4C,SV2B,SCN5A,LGALS3,BVES,SEC24D,SLC36A4,MLC1,MCOLN2,EEF2,SLC30A4,ABCA5,SREBF1,LRP6,GRIP1,BNIP3,SLCO4C1,FAR2,MOXD1,GPR161,CKAP4,RNF152,HMGCR,NOS3,RHOQ,SLC27A2,SLC36A1,VLDLR,HIP1,PEX5L,SNAP25,CLN5,STEAP1,TMEM74,VPS37D,SH3GL2,PMEPA1,HK2,RAB31,PTPRN2,LAPTM4B,PLD1,DHCR7,CDH2,DIRC2,MME,DMXL2,FRMPD3,SORBS1,SCAMP1,RHOD,RNF144A,MYO1B,MSR1,ADD2,LCP2,ZFYVE9,CD53,TLR3,UNC13B,SLC22A17,KMO,STEAP3,CLVS2,RAB27B,SYNGR3,SERPINH1,SNX10,ANTXR2,EVA1A,TUBA1A,FZD4,ADCY1,RAB38,SYNJ2BP,ATP1B1,DSP,GABARAPL1,SNCA,RANBP2,PTPRJ,PAM,MAOA,PTPRS,BMPR1A,ATG5,ARFGEF3,CNTN1,MAN2B2,MYO1D,BMPR2,GLIPR1L1,GRB14,TSPAN15,ATP9A,BACE1,CMTM8,LRP4,SELL,EPHB1,USP30,NDFIP2,RAB11FIP5,TTC1,TECPR1,EHD3,KIAA0319,MARCH3,FIG4,MYO6,ATP2B1,RAB3B,LITAF,PHACTR2,ARHGAP32,ATP11A,TLR6,DKK1,GPLD1,PTPRC,ICA1,MYADM,PRCP,HK1,ATP2B4,STOM |
| 4.441e-02 | -3.11 | heterocycle catabolic process | biological process | GO:0046700 | 455 | 55 | 17256 | 1658 |
RPS20,NUDT10,ADAL,PDE1B,ENO2,BLVRB,TNKS1BP1,NUDT12,RPL13A,QPRT,RPL34,TYMP,PRTFDC1,AADAT,KMO,MGAT1,ALDOC,PDE10A,RPS11,ALDH1L1,PDE4D,ENO1,ZFP36L2,RPS23,SMPDL3A,RPS13,RPL26,GAPDH,PNP,PNRC1,PFKFB2,ALDH1L2,RPL21,OGDHL,PDE8A,AGO4,EXOG,AMDHD1,ISG20,CTIF,ENTPD1,ENPP1,RPL12,RPL28,TDO2,CECR2,ENTPD7,ALDOA,ERN1,HK2,PGM2L1,RPL4,HK1,RPS12,NUDT17 |
| 4.443e-02 | -3.11 | apical part of cell | cellular component | GO:0045177 | 368 | 45 | 18223 | 1724 |
TNIK,AMOTL1,ACVR1,FN1,BMPR2,LDLR,MYO1B,SLC25A27,TJP1,P2RY1,MLC1,EPCAM,CA2,CNKSR3,SLC22A18,MARVELD2,DSG2,PRKG2,MPDZ,PDE4D,DYNC2H1,MYO6,RAB27B,PDGFRB,ATP2B1,SLC3A2,RAPGEF2,PARD3B,ANK2,SHANK2,HOMER2,DCHS1,ABCC2,ATP1B1,PATJ,RIPOR2,FAT4,EDA,CTSV,SLC7A5,DYNC2LI1,OXTR,PLD1,CDH2,OCLN |
| 4.450e-02 | -3.11 | APBA1 (amyloid beta precursor protein binding family A member 1) | protein interactions | 320 | 20 | 5 | 17029 | 1718 |
NRXN1,APBA2,STXBP1,CNTNAP3,APBB1 |
| 4.450e-02 | -3.11 | SCML1 (Scm polycomb group protein like 1) | protein interactions | 6322 | 20 | 5 | 17029 | 1718 |
COBLL1,EPB41L3,AMOTL1,PCGF2,PHC1 |
| 4.450e-02 | -3.11 | KCND2 (potassium voltage-gated channel subfamily D member 2) | protein interactions | 3751 | 20 | 5 | 17029 | 1718 |
DPP10,BAG3,KCNIP3,GNB4,NCS1 |
| 4.450e-02 | -3.11 | RIMS1 (regulating synaptic membrane exocytosis 1) | protein interactions | 22999 | 20 | 5 | 17029 | 1718 |
LRRK1,SNAP25,PDK1,UNC13B,RAB26 |
| 4.450e-02 | -3.11 | AHNAK2 (AHNAK nucleoprotein 2) | protein interactions | 113146 | 20 | 5 | 17029 | 1718 |
PCK2,C1QL4,FKBP11,TNFAIP8L2,GABARAPL1 |
| 4.450e-02 | -3.11 | STX2 (syntaxin 2) | protein interactions | 2054 | 20 | 5 | 17029 | 1718 |
SNAP25,UNC13B,STXBP1,ENO1,VAMP8 |
| 4.450e-02 | -3.11 | ARHGAP5 (Rho GTPase activating protein 5) | protein interactions | 394 | 20 | 5 | 17029 | 1718 |
NPM1,RND2,PXN,RND3,PTPRU |
| 4.450e-02 | -3.11 | TSSK3 (testis specific serine kinase 3) | protein interactions | 81629 | 20 | 5 | 17029 | 1718 |
TRIM9,IKZF3,FUT9,REL,EFHC2 |
| 4.456e-02 | -3.11 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | 248 | 33 | 17377 | 1707 |
ST14,ESRP1,CTBP2,OVOL2,FAM174B,ABHD6,MECOM,EPCAM,BACE2,MARVELD2,LMAN2,MYO6,LRRC8B,MYO10,C3orf52,TTC22,PLS1,ATP1B1,C4orf19,CENPV,CAMK2N1,GALNT3,DDAH1,ICA1,MFSD9,GPR160,HPGD,KLF5,SH3BGRL2,TC2N,SFN,TPT1,CHMP4C |
| 4.457e-02 | -3.11 | GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN | MSigDB lists | GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN | 128 | 19 | 17377 | 1707 |
ANKRD13B,GAPDH,MLF1,CRIP2,COBLL1,CHAC1,F12,SAV1,SNX9,SPATA7,DAGLA,CPNE2,GSTO2,PIK3AP1,TMEM37,THSD1,APBA2,PERP,TBC1D8 |
| 4.461e-02 | -3.11 | SLC9A3R2 (SLC9A3 regulator 2) | protein interactions | 9351 | 85 | 14 | 17029 | 1718 |
SMAD3,WASF3,LPAR2,ABCC4,WWTR1,SGK3,YAP1,SGK1,P2RY1,NPC2,PRKCA,PIBF1,SLCO3A1,ARHGAP44 |
| 4.466e-02 | -3.11 | - | gene3d domains | 3.90.520.10 | 8 | 3 | 8148 | 867 |
SMAD3,SMAD9,SMAD6 |
| 4.467e-02 | -3.11 | regulation of plasma lipoprotein particle levels | biological process | GO:0097006 | 73 | 12 | 17256 | 1658 |
SOAT2,ABCA5,LDLR,VLDLR,MSR1,BMP1,NPC2,NCEH1,PLTP,PRKACB,ABCG1,CES3 |
| 4.467e-02 | -3.11 | synaptic vesicle exocytosis | biological process | GO:0016079 | 73 | 12 | 17256 | 1658 |
DOC2A,TRIM9,UNC13B,SYT12,CADPS2,SNAP25,SYT14,SEPT5,PCLO,TC2N,RIMS2,SNPH |
| 4.467e-02 | -3.11 | purine ribonucleoside metabolic process | biological process | GO:0046128 | 73 | 12 | 17256 | 1658 |
MOCOS,ADAL,RHOQ,PRTFDC1,PNP,MPP1,PEMT,LRRK2,MPP2,AK4,DLG2,MAGI3 |
| 4.467e-02 | -3.11 | protein activation cascade | biological process | GO:0072376 | 73 | 12 | 17256 | 1658 |
CD55,CFH,CFHR1,PRCP,C4A,CR2,C1R,F12,COLEC10,SUSD4,C4BPB,F3 |
| 4.491e-02 | -3.10 | human chr13q34 | chromosome location | human chr13q34 | 63 | 9 | 26185 | 1967 |
IRS2,ADPRHL1,TMCO3,MCF2L-AS1,MCF2L,RASA3,ATP11A,GAS6,GAS6-AS1 |
| 4.498e-02 | -3.10 | GMP metabolic process | biological process | GO:0046037 | 21 | 5 | 17256 | 1658 |
DLG2,PRTFDC1,MPP1,MAGI3,MPP2 |
| 4.498e-02 | -3.10 | NLS-bearing protein import into nucleus | biological process | GO:0006607 | 21 | 5 | 17256 | 1658 |
RANBP2,KPNA3,IPO5,TRPS1,RERE |
| 4.498e-02 | -3.10 | lymph vessel development | biological process | GO:0001945 | 21 | 5 | 17256 | 1658 |
ACVR2B,BMPR2,CCBE1,SYK,HEG1 |
| 4.498e-02 | -3.10 | secondary metabolite biosynthetic process | biological process | GO:0044550 | 21 | 5 | 17256 | 1658 |
TRPC1,CBS,KMO,BDH2,CTH |
| 4.498e-02 | -3.10 | cell surface receptor signaling pathway involved in heart development | biological process | GO:0061311 | 21 | 5 | 17256 | 1658 |
MSX1,BMPR1A,ACVR1,BMP4,HEY1 |
| 4.500e-02 | -3.10 | V$AP1FJ_Q2 | MSigDB lists | V$AP1FJ_Q2 | 257 | 34 | 17377 | 1707 |
FARP1,PLBD2,SLC6A9,ID1,IGFBP6,BLVRB,ASS1,STAT5B,COL27A1,MAP1A,SCRN1,PDGFRB,GAB2,GAPDH,USP2,MEIS2,DSTN,DCHS1,FGF12,VIM,PRDM1,ARRDC4,GNAI1,ISG20,GPR150,GSN,MAP2,PKN3,AKT3,ABI3,GRIN2D,PAX9,HS3ST3B1,LPP |
| 4.500e-02 | -3.10 | GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_EXTERNAL_STIMULUS | 257 | 34 | 17377 | 1707 |
PRKAA2,BMPR2,IL15,ITGA6,CBS,GAS6,BMP6,BAG3,KCNJ4,TLR3,ASNS,PMAIP1,BHLHA15,SREBF1,BNIP3,CADPS2,TLR4,ATP2B1,FZD1,RNF152,FADS1,ATF4,LRRK2,VLDLR,NUAK2,ATF3,CD40,GABARAPL1,ITGA2,XBP1,TNFRSF1A,BMP4,ATG5,RRAGD |
| 4.505e-02 | -3.10 | RIZKI_TUMOR_INVASIVENESS_3D_UP | MSigDB lists | RIZKI_TUMOR_INVASIVENESS_3D_UP | 196 | 27 | 17377 | 1707 |
SLC3A2,AKAP5,TMEM126A,FGF12,MARS,ZNF219,CD7,INPP1,BMP6,FGFR1,GNAI1,MECOM,IRS2,MMP15,IGF1R,PMAIP1,GATA2,CSF1,CCNA1,PAM,GRIP1,FBXL2,TMEFF2,TNFRSF17,GPR161,CYP1B1,PCSK6 |
| 4.505e-02 | -3.10 | GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | 196 | 27 | 17377 | 1707 |
TRPM4,CARD6,EIF4E3,TBC1D1,UBASH3B,STAT4,ST6GAL1,MCTP2,UBAC2,SELL,CALCRL,RASA3,KCTD12,SATB1,INPP1,DOCK2,CEBPB,SPNS1,GPR155,CACNB2,ITGB3,ERN1,PTPRE,SNX10,CPE,PRKACB,RBMS2 |
| 4.505e-02 | -3.10 | MODULE_67 | MSigDB lists | MODULE_67 | 196 | 27 | 17377 | 1707 |
ARAP2,BVES,KLHL4,FBXO4,SOX21,ELMOD1,HERC5,PEX5L,ZFPM2,NRXN1,RAC3,KREMEN1,EYA4,PPP2R3A,RND2,IQCH,KIAA1257,DACT1,SQLE,UACA,ACVR2A,FBXO27,BTRC,CES3,PCSK5,RPS13,PARP9 |
| 4.505e-02 | -3.10 | GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION | 222 | 30 | 17377 | 1707 |
PNP,LGALS3,IL15,UBASH3B,PTPN6,GATA3,LILRB1,MAFB,STAT5B,PRDM1,GAS6,PRKCA,SPINK5,CEBPB,TLR3,IKZF3,CA2,NCKAP1L,GATA2,MYC,CSF1,XBP1,PRELID1,BCL6,BMP4,TNFSF4,TLR4,TESC,SYK,RASGRP1 |
| 4.505e-02 | -3.10 | V$E2A_Q2 | MSigDB lists | V$E2A_Q2 | 222 | 30 | 17377 | 1707 |
PHACTR3,BCL7A,SCN5A,USP2,KCNIP3,ANKRD13B,ACVR1,GCAT,KCNH5,ITGA6,RAPGEF4,PRDM8,IKZF2,CHD5,CBLN1,EYA4,CYP26A1,GPRC5B,RPL28,KIAA0355,PTK7,LRP6,TMED9,DLX2,LOXL4,PPP2R2B,SEPT3,MID1,SLIT2,GAB2 |
| 4.506e-02 | -3.10 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-virilizing_syndrome_producing | 303 | 39 | 17385 | 1698 |
BCL11B,MOCOS,DNM3,WDR17,TCP11L2,ST14,ADSSL1,DOK5,PCLO,HMCN1,MTUS1,IRX5,FRY,UNC13B,NOVA2,GPR155,MYO3B,EBF4,SLC2A12,NCEH1,COL4A4,KLHL4,LRMP,MARS,PRDM1,RNF44,DOCK5,LDHD,MAP1B,NSD1,PCDHB7,PMEPA1,TERT,MYOM2,GRB10,DHCR7,XKR4,FILIP1,CTNND2 |
| 4.507e-02 | -3.10 | Endocrine and other factor-regulated calcium reabsorption | KEGG pathways | hsa04961 | 47 | 9 | 7161 | 730 |
DNM3,PRKCB,ADCY6,ATP1B1,PRKCA,PLCB1,ATP2B1,PRKACB,ATP1A3 |
| 4.507e-02 | -3.10 | Endocrine and other factor-regulated calcium reabsorption | KEGG pathways | ko04961 | 47 | 9 | 7161 | 730 |
DNM3,PRKCB,ADCY6,ATP1B1,PRKCA,PLCB1,ATP2B1,PRKACB,ATP1A3 |
| 4.516e-02 | -3.10 | fatty acid metabolic process | biological process | GO:0006631 | 308 | 39 | 17256 | 1658 |
PLA2G4A,PRKAA2,ACSL1,ALOX5AP,ELOVL4,EHHADH,CYP2J2,OLAH,ELOVL7,CYP4V2,STAT5B,SCD,LPIN3,MSMO1,FAAH2,GHR,PCK2,CYP1B1,FADS1,GSTM2,SESN2,SLC27A2,ELOVL3,HACD1,FASN,PRKAR2B,AIG1,SNCA,DAGLA,XBP1,BDH2,PAM,TNFRSF1A,HPGD,CYP2U1,PPARGC1A,PTGES,ACSM3,CRYL1 |
| 4.519e-02 | -3.10 | ATP-dependent microtubule motor activity | molecular function | GO:1990939 | 49 | 9 | 17224 | 1680 |
DNAH6,KIF5A,DYNC2LI1,KIF5C,DYNC2H1,DNHD1,DNAH5,DYNC1I1,KIF1B |
| 4.528e-02 | -3.09 | cell-cell adhesion via plasma-membrane adhesion molecules | biological process | GO:0098742 | 227 | 30 | 17256 | 1658 |
TENM1,PCDH10,CDH26,PCDH18,ACVR1,CELSR1,ROBO2,PTPRD,CELSR3,DCHS1,CLSTN2,SELL,CADM2,AMIGO1,SDK1,NRXN1,CBLN1,PCDH7,PCDHB14,GYPC,PCDHB7,FAT4,CLDN12,FLRT3,FAT1,DSG2,SCARF2,ADGRL1,CDH17,CDH2 |
| 4.531e-02 | -3.09 | Integrin-mediated Cell Adhesion | WikiPathways | WP185 | 103 | 17 | 5312 | 569 |
PAK1,VAV3,ITGB7,PXN,SORBS1,DOCK1,ITGA6,CAPN5,TNS1,MAPK4,SELENOP,RAC3,MAP2K6,AKT3,ITGB3,ITGA2,MAPK10 |
| 4.531e-02 | -3.09 | CFB (complement factor B) | protein interactions | 629 | 14 | 4 | 17029 | 1718 |
LAMC3,NPC2,FN1,GDPD1 |
| 4.531e-02 | -3.09 | SLC25A15 (solute carrier family 25 member 15) | protein interactions | 10166 | 14 | 4 | 17029 | 1718 |
JCHAIN,C4BPB,EYA4,FAM131B |
| 4.531e-02 | -3.09 | CWC25 (CWC25 spliceosome associated protein homolog) | protein interactions | 54883 | 14 | 4 | 17029 | 1718 |
LAMC3,CGN,CBY1,LPIN3 |
| 4.531e-02 | -3.09 | CDK10 (cyclin dependent kinase 10) | protein interactions | 8558 | 14 | 4 | 17029 | 1718 |
ACTA2,PLS1,FAM84B,MGMT |
| 4.531e-02 | -3.09 | ARHGAP36 (Rho GTPase activating protein 36) | protein interactions | 158763 | 14 | 4 | 17029 | 1718 |
PTPRD,CLN5,CAND2,STOM |
| 4.531e-02 | -3.09 | DLGAP2 (DLG associated protein 2) | protein interactions | 9228 | 14 | 4 | 17029 | 1718 |
DLGAP1,NLGN4X,SHANK2,ADRB1 |
| 4.531e-02 | -3.09 | RYR1 (ryanodine receptor 1) | protein interactions | 6261 | 14 | 4 | 17029 | 1718 |
RYR2,HOMER2,PRKG1,HOMER3 |
| 4.531e-02 | -3.09 | GPAT4 (glycerol-3-phosphate acyltransferase 4) | protein interactions | 137964 | 14 | 4 | 17029 | 1718 |
TCTN2,TES,TSPAN17,GSDME |
| 4.531e-02 | -3.09 | ZNF440 (zinc finger protein 440) | protein interactions | 126070 | 14 | 4 | 17029 | 1718 |
MID2,PAX9,PJA1,XBP1 |
| 4.531e-02 | -3.09 | RIMS2 (regulating synaptic membrane exocytosis 2) | protein interactions | 9699 | 14 | 4 | 17029 | 1718 |
RABAC1,RAB3B,MYC,RAPGEF4 |
| 4.531e-02 | -3.09 | RGS7 (regulator of G protein signaling 7) | protein interactions | 6000 | 14 | 4 | 17029 | 1718 |
MSX1,PRKCA,GNAO1,GNAI1 |
| 4.531e-02 | -3.09 | TEX45 (testis expressed 45) | protein interactions | 374877 | 14 | 4 | 17029 | 1718 |
CADPS2,KLHL23,PTPRD,FGFR1 |
| 4.531e-02 | -3.09 | HNF4G (hepatocyte nuclear factor 4 gamma) | protein interactions | 3174 | 14 | 4 | 17029 | 1718 |
NSD1,GAPDH,HLF,PNRC1 |
| 4.531e-02 | -3.09 | LGALS13 (galectin 13) | protein interactions | 29124 | 14 | 4 | 17029 | 1718 |
CREB5,HOXA1,CENPV,PACSIN3 |
| 4.531e-02 | -3.09 | ADRA2A (adrenoceptor alpha 2A) | protein interactions | 150 | 14 | 4 | 17029 | 1718 |
GNAO1,PRKCD,ADRB1,GNAI1 |
| 4.531e-02 | -3.09 | OSTM1 (osteopetrosis associated transmembrane protein 1) | protein interactions | 28962 | 14 | 4 | 17029 | 1718 |
RGS17,LGALS3,GPSM1,RGS20 |
| 4.531e-02 | -3.09 | EFNA5 (ephrin A5) | protein interactions | 1946 | 14 | 4 | 17029 | 1718 |
EPHA3,GRIP1,EPHB1,MYC |
| 4.531e-02 | -3.09 | GMPPA (GDP-mannose pyrophosphorylase A) | protein interactions | 29926 | 14 | 4 | 17029 | 1718 |
HECW2,BTC,PAK5,LPP |
| 4.531e-02 | -3.09 | GSTM4 (glutathione S-transferase mu 4) | protein interactions | 2948 | 14 | 4 | 17029 | 1718 |
GSTM3,BAG3,GSTM2,GSTM4 |
| 4.531e-02 | -3.09 | CCDC88C (coiled-coil domain containing 88C) | protein interactions | 440193 | 14 | 4 | 17029 | 1718 |
NSD2,LATS2,BAG3,ALDH1L1 |
| 4.531e-02 | -3.09 | TREML2 (triggering receptor expressed on myeloid cells like 2) | protein interactions | 79865 | 14 | 4 | 17029 | 1718 |
CYP51A1,SQLE,ALG11,PDZD8 |
| 4.531e-02 | -3.09 | SSTR3 (somatostatin receptor 3) | protein interactions | 6753 | 14 | 4 | 17029 | 1718 |
TJP1,MPDZ,MAGI3,GNAI1 |
| 4.531e-02 | -3.09 | KCNJ2 (potassium voltage-gated channel subfamily J member 2) | protein interactions | 3759 | 14 | 4 | 17029 | 1718 |
DLG2,KCNJ4,AKAP5,PATJ |
| 4.531e-02 | -3.09 | BACH2 (BTB domain and CNC homolog 2) | protein interactions | 60468 | 14 | 4 | 17029 | 1718 |
DDIT3,BATF3,BCL6,NFE2L1 |
| 4.531e-02 | -3.09 | HOXC8 (homeobox C8) | protein interactions | 3224 | 14 | 4 | 17029 | 1718 |
MSX1,DLX2,BMPR1A,SMAD6 |
| 4.531e-02 | -3.09 | BPIFB1 (BPI fold containing family B member 1) | protein interactions | 92747 | 14 | 4 | 17029 | 1718 |
TMEM237,PCK2,MLLT3,PTPN21 |
| 4.534e-02 | -3.09 | microtubule | cellular component | GO:0005874 | 406 | 49 | 18223 | 1724 |
EML5,DNM3,FGF13,HID1,CKAP2,KIF5A,TUBE1,KIF5C,LRRC49,KIF21B,DYNC1I1,RADIL,MTUS1,FSD1,TUBB4A,NAV1,MAP1A,DNAH6,GAS2L3,RMDN2,MAP7,DYNC2H1,FIGN,DNAH5,SPRY2,BOD1,DISC1,MID2,TUBA1A,EML6,SYBU,FEZ1,TTLL7,EML1,BAIAP2,MAP10,GABARAPL1,MAP1B,BEX4,MAP2,CCDC181,MAP9,DYNC2LI1,SVIL,KIF21A,KIF1B,MID1,SHTN1,SNPH |
| 4.538e-02 | -3.09 | FTO Obesity Variant Mechanism | WikiPathways | WP3407 | 8 | 3 | 5312 | 569 |
IRX5,PPARGC1A,ARID5B |
| 4.538e-02 | -3.09 | Folate-Alcohol and Cancer Pathway | WikiPathways | WP1589 | 8 | 3 | 5312 | 569 |
CEBPB,CBS,ALDH1L1 |
| 4.538e-02 | -3.09 | NAD Biosynthesis II (from tryptophan) | WikiPathways | WP2485 | 8 | 3 | 5312 | 569 |
TDO2,KMO,QPRT |
| 4.539e-02 | -3.09 | POOLA_INVASIVE_BREAST_CANCER_UP | MSigDB lists | POOLA_INVASIVE_BREAST_CANCER_UP | 266 | 35 | 17377 | 1707 |
RGS16,FN1,IL32,GPR65,SELL,LILRB1,GPSM2,LCP2,DOCK2,IL18R1,FKBP11,HOPX,CD53,KMO,SP140,PRR16,GAB2,LAMP3,ABCC4,STAT4,LRMP,MAFB,CALCRL,COTL1,CD40,TPK1,ISG20,PTPRC,CXCL10,TDO2,PRKCB,GBP1,SLC7A5,SQLE,TNFSF4 |
| 4.539e-02 | -3.09 | WALLACE_PROSTATE_CANCER_RACE_UP | MSigDB lists | WALLACE_PROSTATE_CANCER_RACE_UP | 266 | 35 | 17377 | 1707 |
BCL11B,RGS16,ALOX5AP,IL15,CKAP2,GPR65,SELL,HERC5,LCP2,HERC6,CD53,TYMP,CHRDL1,GSTM3,PLTP,RASGRP1,CEBPD,LAMP3,GPM6A,COTL1,ISG20,IRS2,PTPRC,CD37,GPRC5B,PDLIM3,FBN1,NCKAP1L,GBP1,SLC7A5,AHNAK2,PPARGC1A,CDH2,PSPH,STOM |
| 4.540e-02 | -3.09 | GO_CARTILAGE_DEVELOPMENT | MSigDB lists | GO_CARTILAGE_DEVELOPMENT | 145 | 21 | 17377 | 1707 |
CREB3L2,MSX1,RUNX2,SMAD9,BMPR2,SATB2,CHSY1,BMP6,FGFR1,COL27A1,GPLD1,BMP1,LRP6,DLX2,BMP4,BMPR1A,SERPINH1,SHOX2,SNAI2,SIX2,MEF2C |
| 4.540e-02 | -3.09 | GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP | MSigDB lists | GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP | 145 | 21 | 17377 | 1707 |
TMEM65,ADM2,NR4A1,GPR65,LITAF,ATF3,PRDM1,TBC1D30,PLEKHB1,CEBPB,PMAIP1,PLK2,ZIC5,SGK1,HRK,SPRY4,GEM,ARL4D,SPRY2,CEBPD,DUSP1 |
| 4.540e-02 | -3.09 | GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 145 | 21 | 17377 | 1707 |
PFKFB4,SCAMP1,MPP1,GDPD1,RAPGEF4,LITAF,SPATA13,MSR1,VIM,RABAC1,NPC2,DENND3,CDS1,EHD3,TMEM86A,ANKFN1,BCL6,PTPRS,SLC16A9,TNFSF4,STOM |
| 4.542e-02 | -3.09 | SH3_1 | pfam domains | PF00018 | 96 | 15 | 17054 | 1666 |
SORBS1,FGR,SKAP2,SH3RF1,EPS8,SPATA13,SRGAP1,SORBS3,SH3PXD2B,FRK,DOCK5,FNBP1L,SNX9,SKAP1,NPHP1 |
| 4.544e-02 | -3.09 | negative regulation of transport | biological process | GO:0051051 | 465 | 56 | 17256 | 1658 |
EPHA3,PRKN,NECAB2,FN1,C1QTNF3,STXBP5L,LGALS3,LGR4,STXBP6,VAMP8,UBAC2,HECW2,LILRB1,GAS6,P2RY1,ABAT,NDFIP2,PPP1R9A,NEDD4,RAB11FIP5,KCNAB1,TCAF2,ITGB3,SREBF1,PRKG2,PACSIN1,NOS3,HMGCR,ATF4,GSTM2,CSN2,ACVR1C,LRRK2,PACSIN3,FGF12,GSTO1,RACK1,CTTNBP2NL,TLR6,SERGEF,MAP1B,SNCA,IRS2,TRIM9,ENPP1,INSIG1,PRKCB,GBP1,GNAO1,ASIC1,GRB10,OXTR,GEM,ATG5,TBC1D4,PKIA |
| 4.545e-02 | -3.09 | MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_DN | MSigDB lists | MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_DN | 120 | 18 | 17377 | 1707 |
TRPM4,PRAME,NBL1,ST14,ATP9A,LRP4,LDLR,CD7,DENND3,HEG1,RERE,RPL28,PMAIP1,SVIL,SCRN1,PDE4D,RNF130,PCSK6 |
| 4.545e-02 | -3.09 | GTGCAAA,MIR-507 | MSigDB lists | GTGCAAA,MIR-507 | 120 | 18 | 17377 | 1707 |
MOB1B,LONRF1,GRIK2,ESRRG,STAT5B,PRDM1,ATP1B1,CTNNA2,ZIC1,BCL11A,NELL2,RGS17,BACH2,EMILIN2,DAB2IP,BMP4,IQSEC2,SCN3A |
| 4.551e-02 | -3.09 | GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_DN | MSigDB lists | GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_DN | 179 | 25 | 17377 | 1707 |
FAM171B,ANTXR2,ANKRD13D,ALOX5AP,RNF170,TDRD3,PARD3B,NSUN6,C20orf194,HECW2,COL18A1,EFHC1,TPD52L1,TTC30B,CPEB1,CCNJ,TIFA,PPFIBP1,AHNAK2,ALG11,PCOLCE2,ARL4D,STXBP1,SNX10,CSRP2 |
| 4.551e-02 | -3.09 | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP | 179 | 25 | 17377 | 1707 |
MN1,DZANK1,WASF3,MICAL2,FZD4,GABRB2,RBFOX2,NPM3,MPP1,LMCD1,BNIP3L,MARS,GDPD5,TIAM2,DDIT4,HOMER3,SLC7A1,RPS6KA2,ITGA2,ACVR2A,PLD1,PCK2,SPRY2,RAPGEF5,PNMA2 |
| 4.551e-02 | -3.09 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | 179 | 25 | 17377 | 1707 |
BCL7A,SCN5A,EVL,ZNF516,SH3BP2,TBC1D1,ARHGAP22,DCHS1,ADCY1,PLEKHA1,CD40,SATB1,SKAP1,SESN1,ATP10D,ZNF266,HPS1,KMO,PAIP2B,PPFIBP1,BCL6,PIK3C2B,RPS23,TPT1,PHC1 |
| 4.559e-02 | -3.09 | sensory organ morphogenesis | biological process | GO:0090596 | 245 | 32 | 17256 | 1658 |
MSX1,CELSR1,NKX3-2,OTX1,GATA3,MAFB,PRDM1,SDK1,ATOH1,EPHB1,FOXG1,HOXA1,FGFR1,ZIC1,TSKU,SKI,EFEMP1,IRX5,INSIG1,PDZD7,FBN1,GATA2,DLX6,PTK7,WDR19,TFAP2A,MYO3B,LRP6,TSPAN12,BMP4,SPRY2,SIX2 |
| 4.564e-02 | -3.09 | GO_ENDOSOME | MSigDB lists | GO_ENDOSOME | 742 | 87 | 17377 | 1707 |
EXPH5,EPHA3,SCAMP1,IL15,RHOD,MYO1B,VAMP8,LDLR,DNER,SNX9,ZFYVE9,SLC9A7,CCDC120,RND2,TLR3,TM9SF2,ZFYVE28,RAP2A,STEAP3,PACSIN1,CLVS2,RAB27B,TLR4,SNX10,LAMP3,TNK2,ANTXR2,TUBA1A,WLS,LRRK2,PANK1,RAB38,TBC1D16,ATP7B,ADRB1,INPP5F,NRP1,MAGI2,CHMP4C,RRAGD,TNIK,MYO1D,ANKRD13D,ANKRD13B,PRSS16,GRB14,ATP9A,BACE1,PKN1,NDFIP2,EPHB1,MLC1,DYNC1I1,ARHGAP44,RAB11FIP5,SLC30A4,BACE2,ABCA5,EHD3,KIAA0319,SGK3,TRIM3,MARCH3,GRIP1,ADCY6,LRP6,FIG4,GPR161,SNX7,FGFR4,SLC40A1,RAPGEF2,PACSIN3,CALCRL,ATP11A,ARHGAP32,ARRDC4,LRAT,STEAP1,DKK1,VPS37D,PMEPA1,RAB31,PLD1,DDIT3,ABCG1,TPT1 |
| 4.566e-02 | -3.09 | Tryptophan metabolism | KEGG pathways | hsa00380 | 40 | 8 | 7161 | 730 |
ALDH2,AADAT,EHHADH,TDO2,KMO,OGDHL,MAOA,CYP1B1 |
| 4.566e-02 | -3.09 | Tryptophan metabolism | KEGG pathways | ko00380 | 40 | 8 | 7161 | 730 |
ALDH2,EHHADH,AADAT,TDO2,KMO,OGDHL,MAOA,CYP1B1 |
| 4.566e-02 | -3.09 | Ferroptosis | KEGG pathways | hsa04216 | 40 | 8 | 7161 | 730 |
SLC39A14,STEAP3,SLC40A1,SLC3A2,ACSL1,ATG5,SLC7A11,SLC39A8 |
| 4.566e-02 | -3.09 | Ferroptosis | KEGG pathways | ko04216 | 40 | 8 | 7161 | 730 |
SLC39A14,STEAP3,SLC40A1,SLC3A2,ACSL1,ATG5,SLC7A11,SLC39A8 |
| 4.567e-02 | -3.09 | GO_CARBOHYDRATE_HOMEOSTASIS | MSigDB lists | GO_CARBOHYDRATE_HOMEOSTASIS | 162 | 23 | 17377 | 1707 |
FGFR4,PRKAA2,SESN2,STXBP5L,FN1,CEBPA,GAS6,LEPR,MCU,IRS2,RAB11FIP5,RANBP2,GPRC5B,PRCP,BHLHA15,WFS1,ERN1,XBP1,HK2,PTPRN2,HK1,PPARGC1A,FOXA1 |
| 4.567e-02 | -3.09 | GO_RESPONSE_TO_CARBOHYDRATE | MSigDB lists | GO_RESPONSE_TO_CARBOHYDRATE | 162 | 23 | 17377 | 1707 |
SESN2,COL6A2,FN1,ACVR1C,PFKFB2,CALCRL,PRKCQ,ACVR2B,GAS6,ILDR2,GPLD1,NKX6-1,IRS2,RAB11FIP5,RPS6KA2,PRKCB,MAP2K6,ERN1,XBP1,ITGA2,SREBF1,PTPRN2,PPARGC1A |
| 4.567e-02 | -3.09 | GO_GLUCOSE_HOMEOSTASIS | MSigDB lists | GO_GLUCOSE_HOMEOSTASIS | 162 | 23 | 17377 | 1707 |
FGFR4,PRKAA2,SESN2,STXBP5L,FN1,CEBPA,GAS6,LEPR,MCU,IRS2,RAB11FIP5,RANBP2,GPRC5B,PRCP,BHLHA15,WFS1,ERN1,XBP1,HK2,PTPRN2,HK1,PPARGC1A,FOXA1 |
| 4.567e-02 | -3.09 | RNF mutants show enhanced WNT signaling and proliferation | REACTOME pathways | R-HSA-5340588 | 9 | 3 | 10287 | 971 |
LRP6,FZD4,FZD8 |
| 4.567e-02 | -3.09 | Crosslinking of collagen fibrils | REACTOME pathways | R-HSA-2243919 | 9 | 3 | 10287 | 971 |
LOXL4,BMP1,TLL2 |
| 4.567e-02 | -3.09 | Ca2+ activated K+ channels | REACTOME pathways | R-HSA-1296052 | 9 | 3 | 10287 | 971 |
KCNMB4,KCNN2,KCNMB3 |
| 4.578e-02 | -3.08 | KRTAP4-12 (keratin associated protein 4-12) | protein interactions | 83755 | 109 | 17 | 17029 | 1718 |
PLSCR4,OTX1,CREB5,NPDC1,TBC1D16,HOXA1,BEX2,TXNDC5,RERE,QPRT,FAM27E3,ZNF440,THAP10,HOXB9,SPRY2,PDGFRB,PCSK5 |
| 4.590e-02 | -3.08 | regulation of neuron migration | biological process | GO:2001222 | 35 | 7 | 17256 | 1658 |
NKX6-1,DAB2IP,NRG3,SEMA3A,RAPGEF2,SEMA6A,SHTN1 |
| 4.590e-02 | -3.08 | negative chemotaxis | biological process | GO:0050919 | 35 | 7 | 17256 | 1658 |
SEMA3C,NRG3,SEMA4F,SEMA3A,FLRT3,SLIT2,ITGB3 |
| 4.590e-02 | -3.08 | negative regulation of smooth muscle cell migration | biological process | GO:0014912 | 35 | 7 | 17256 | 1658 |
BMPR1A,TPM1,PPARGC1A,SLIT2,MEF2C,IGFBP3,PRKG1 |
| 4.591e-02 | -3.08 | GO_CELLULAR_MODIFIED_AMINO_ACID_METABOLIC_PROCESS | MSigDB lists | GO_CELLULAR_MODIFIED_AMINO_ACID_METABOLIC_PROCESS | 205 | 28 | 17377 | 1707 |
PLA2G4A,VNN2,SERINC5,GDAP1,OPLAH,GSTM2,ALDH1L2,GSTM4,FASN,ASS1,CBS,GSTO1,STAT5B,CHAC1,DDAH1,GSTO2,AADAT,TDO2,KMO,PEMT,ALDH1L1,GHR,SERINC2,GSTM3,P4HA1,GATM,OCLN,CTH |
| 4.593e-02 | -3.08 | positive regulation of proteasomal protein catabolic process | biological process | GO:1901800 | 106 | 16 | 17256 | 1658 |
LONRF1,PRKN,NOP53,RNF144A,LRRK2,PRICKLE1,RNF125,CEBPA,RACK1,HERPUD1,RNF180,TRIB3,RNF217,PLK2,XBP1,DAB2IP |
| 4.597e-02 | -3.08 | presynaptic active zone cytoplasmic component | cellular component | GO:0098831 | 9 | 3 | 18223 | 1724 |
UNC13B,PCLO,RIMS2 |
| 4.602e-02 | -3.08 | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | MSigDB lists | REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | 64 | 11 | 17377 | 1707 |
COL9A3,COL6A2,COL4A3,CACNB2,COL4A4,COL4A5,NCAM1,CACNB4,GFRA1,COL9A2,FGFR1 |
| 4.602e-02 | -3.08 | GO_ADHERENS_JUNCTION_ORGANIZATION | MSigDB lists | GO_ADHERENS_JUNCTION_ORGANIZATION | 64 | 11 | 17377 | 1707 |
NUMBL,SORBS1,RHOD,ITGA2,CDH17,PKP2,FERMT2,CADM2,CTTN,CDH2,DSP |
| 4.603e-02 | -3.08 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | 940 | 108 | 17377 | 1707 |
EPHA3,NMNAT3,BTC,NEK10,MVK,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,CDS1,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,FER,TNK2,MYLK3,MARK1,PDK1,PFKFB2,ACVR1C,KCNH5,PANK1,LRRK2,PRKCQ,ROR1,ACVR2B,FGF17,SGK2,FRK,FGFR1,MAGI3,TPK1,IRS2,DYRK1B,AK1,PRKCB,PLK2,PTK7,ERN1,PIK3C2B,MAPK13,BMPR1A,NRP1,MAPK10,MAST1,PRKAA2,TYRO3,TNIK,LATS2,DYRK3,BMPR2,SLK,EPHB1,PKN1,EFEMP1,IGF1R,ADCK1,PRKCD,SGK3,PRKG1,PRKG2,SGK1,ALPK1,MAST4,SYK,FES,PFKFB4,FGFR4,PAK1,CRIM1,MPP1,NUAK2,EFNA3,OBSCN,STRADB,AK4,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,TERT,MAP2K6,AKT3,HK2,MPP2,PGM2L1,NEK11,DLG2,PIP5KL1,LRRK1,HK1,CMPK2,PANK3 |
| 4.607e-02 | -3.08 | early endosome | cellular component | GO:0005769 | 341 | 42 | 18223 | 1724 |
EPHA3,ANKRD13B,RHOD,BACE1,ATP9A,LDLR,MYO1B,VAMP8,MCOLN3,EPHB1,MLC1,DNER,ZFYVE9,RND2,ADPRHL1,RAB11FIP5,TLR3,ZFYVE28,KIAA0319,SGK3,LRP6,MARCH3,TRIM3,FIG4,CLVS2,TLR4,LAMP3,ANK2,WLS,LITAF,RAB38,ATP11A,ARRDC4,TBC1D16,DKK1,SH3GL2,PMEPA1,RAB31,ADRB1,LAPTM4B,INPP5F,NRP1 |
| 4.610e-02 | -3.08 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG pathways | ko00532 | 20 | 5 | 7161 | 730 |
CHSY3,UST,CHSY1,B4GALT7,XYLT1 |
| 4.610e-02 | -3.08 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate | KEGG pathways | hsa00532 | 20 | 5 | 7161 | 730 |
CHSY3,UST,CHSY1,XYLT1,B4GALT7 |
| 4.616e-02 | -3.08 | secretory granule membrane | cellular component | GO:0030667 | 304 | 38 | 18223 | 1724 |
FRMPD3,LGALS3,SCAMP1,ATP8A1,VAMP8,SELL,ITPR2,PCDH7,CD53,RND2,ITGB3,RAB26,SLCO4C1,RAB27B,MOXD1,CPE,CKAP4,LAMP3,CD55,ABCC4,SLC27A2,LRMP,PHACTR2,ATP11A,SNAP25,DSP,SNCA,PTPRC,PTPRJ,ICA1,NCKAP1L,PRCP,RAB31,PAM,PTPRN2,PLD1,MME,STOM |
| 4.622e-02 | -3.07 | GO_RAB_GTPASE_BINDING | MSigDB lists | GO_RAB_GTPASE_BINDING | 112 | 17 | 17377 | 1707 |
EXPH5,DMXL2,STXBP5L,TBC1D8B,TBC1D1,RUSC2,TBC1D16,TBC1D30,TBC1D2,ADPRHL1,RAB11FIP5,TBC1D9,TBC1D4,MYRIP,RIMS2,TBC1D8,HACE1 |
| 4.622e-02 | -3.07 | V$ER_Q6_02 | MSigDB lists | V$ER_Q6_02 | 240 | 32 | 17377 | 1707 |
EFNB2,PCDH18,BDNF,RHOQ,TMEM43,NR6A1,FZD4,KIF5A,DCHS1,SLC25A27,FGF12,EFNA3,GABRG2,NDRG2,MAFB,OVOL2,RGS7,SATB1,SLCO3A1,HPCAL4,CYP26A1,SPATA7,CEBPB,CD37,PPM1E,MYADM,CLDN12,MPPED2,BCL6,NXPH4,INPP5F,MID1 |
| 4.622e-02 | -3.07 | V$PAX2_02 | MSigDB lists | V$PAX2_02 | 240 | 32 | 17377 | 1707 |
PHACTR3,TRIM2,RASAL2,ST6GAL1,EPHB1,PHGDH,DNER,SLCO3A1,RPL13A,PCDH7,RTN1,FOXP2,ATXN7L1,EPB41L3,UNC13B,AKAP7,BCL6,TSPAN13,MARCKS,PPP2R2B,TMEM56,MN1,BDNF,MEIS2,EVL,KLHL3,ESRRG,CD40,ZFPM2,HTR7,SERPINI1,RNF122 |
| 4.622e-02 | -3.07 | V$STAT_Q6 | MSigDB lists | V$STAT_Q6 | 240 | 32 | 17377 | 1707 |
PHACTR3,FN1,NTRK3,FAM198B,APBA1,SEMA6A,PPP2R3A,RTN1,SPEG,CDC14B,FLRT3,BCL6,SERINC2,POF1B,LMAN2,PROS1,MOXD1,AGL,SCN3A,RNF152,PTCH2,TMTC4,NFIA,PRICKLE1,AGAP2,CTTNBP2NL,PRDM1,ASPH,CLN5,BACH2,LAPTM4B,PPARGC1A |
| 4.627e-02 | -3.07 | GTGACGY_V$E4F1_Q6 | MSigDB lists | GTGACGY_V$E4F1_Q6 | 612 | 73 | 17377 | 1707 |
MPZL3,PHACTR3,ID1,CHUK,SEZ6L2,PCDH7,CYP51A1,PDZD8,CDC14B,DACT1,TMEM86A,SERINC2,SYNGR3,ARL4D,PRKACB,GLI1,ATL1,PNRC1,NR6A1,ANK2,PRDM13,PNMA6A,RNF44,GPC6,BCL11A,ZNF711,RANBP2,PDLIM3,PLK2,B3GALT2,MAOA,ZBTB20,ATG5,PPARGC1A,BCL11B,CCDC148,MRC2,RHOBTB1,ZCCHC24,BLVRB,ARL2,RASD1,COL4A5,SFXN3,CHD5,ARHGAP44,RPL13A,RNF141,PDZD7,DSG2,EIF1,SLC6A15,KLF9,FBXL2,RBMS2,DUSP1,NDUFA4L2,PCDH10,PPP1R3D,USP2,NR4A1,HOXA1,SPATA7,RERE,CTIF,XBP1,HK2,GEM,KIF1B,FOXA1,PHC1,DOCK9,TPT1 |
| 4.630e-02 | -3.07 | SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | REACTOME pathways | R-HSA-399955 | 15 | 4 | 10287 | 971 |
NRP1,SEMA3A,FES,PLXNA2 |
| 4.635e-02 | -3.07 | blood circulation | biological process | GO:0008015 | 382 | 47 | 17256 | 1658 |
SCN5A,BMPR2,PKP2,GAS6,P2RY1,ABAT,KCNN2,SCN1B,CACNB2,PRKG1,ACTA2,SGK1,ADCY6,PDE4D,SLIT2,CHRM3,NOS3,TBC1D8,HMGCR,TRPM4,VEGFC,MYLK3,COL4A3,ADM2,ANK2,FGF12,RYR2,KCND3,ATP1B1,DOCK5,GJC1,HTR7,SMAD3,DDAH1,CXCL10,KCNMB4,PTPRJ,PRCP,MAP2K6,ADRB1,OXTR,ATG5,TPM1,CACNA2D1,MME,ACSM3,PCSK5 |
| 4.644e-02 | -3.07 | CYFIP2 (cytoplasmic FMR1 interacting protein 2) | protein interactions | 26999 | 55 | 10 | 17029 | 1718 |
WASF3,NCKAP1L,APBB1,ABI3,PACSIN3,PACSIN1,PTPRE,BAIAP2,HOMER3,CGB2 |
| 4.644e-02 | -3.07 | INPP5D (inositol polyphosphate-5-phosphatase D) | protein interactions | 3635 | 55 | 10 | 17029 | 1718 |
FGR,INPPL1,CLYBL,UBASH3B,PRKCD,LRRK1,MET,SYK,MME,GAB2 |
| 4.644e-02 | -3.07 | RAP2A (RAP2A, member of RAS oncogene family) | protein interactions | 5911 | 55 | 10 | 17029 | 1718 |
TNIK,ACVR1,SLC30A4,MARVELD2,RAP2A,RAPGEF4,SGK1,GRIN2D,RAPGEF5,NEDD4 |
| 4.654e-02 | -3.07 | C2 | pfam domains | PF00168 | 121 | 18 | 17054 | 1666 |
PLA2G4A,DOC2A,RASAL2,SYT12,MCTP2,HECW2,RASA3,SYT14,PRKCA,PCLO,RAB11FIP5,CPNE2,UNC13B,PRKCB,DAB2IP,PIK3C2B,TC2N,RIMS2 |
| 4.655e-02 | -3.07 | GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_UP | MSigDB lists | GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_UP | 137 | 20 | 17377 | 1707 |
VAV3,KCNIP3,TCP11L2,AGPAT4,RIMKLA,LRMP,PHACTR2,GABRR2,RABAC1,SLC1A3,SFXN3,NHP2,HOPX,TMEM154,KMO,PDZD7,KCNS3,GRIP1,MARCH3,SMPDL3A |
| 4.656e-02 | -3.07 | voltage-gated channel activity | molecular function | GO:0022832 | 198 | 27 | 17224 | 1680 |
KCNV1,SCN5A,KCNIP3,CACNG3,KCNQ3,CACNA1E,SCN8A,KCNH5,GAS6,KCND3,KCNC4,CACNB4,NCS1,KCNJ4,LRRC55,KCNK15,KCNAB1,SCN1B,CACNB2,KCNG1,KCNS3,GRIN2D,TMEM37,SCN2A,SCN3A,KCNB2,CACNA2D1 |
| 4.656e-02 | -3.07 | voltage-gated ion channel activity | molecular function | GO:0005244 | 198 | 27 | 17224 | 1680 |
KCNV1,SCN5A,KCNIP3,CACNG3,KCNQ3,CACNA1E,SCN8A,KCNH5,GAS6,KCND3,KCNC4,CACNB4,NCS1,KCNJ4,LRRC55,KCNK15,KCNAB1,SCN1B,CACNB2,KCNG1,KCNS3,GRIN2D,TMEM37,SCN2A,SCN3A,KCNB2,CACNA2D1 |
| 4.657e-02 | -3.07 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_UP | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_1H_UP | 188 | 26 | 17377 | 1707 |
PPP4R4,MYLK3,NR6A1,ST14,NPM3,DNAJC3,ST6GAL1,MORC4,CREB5,SATB1,KCNC4,LDHD,STK24,ZFYVE9,CHST10,ARHGEF10L,GRHL1,NCKAP1L,ENTPD7,ADRB1,PRKG1,NBEA,PROS1,MET,MOXD1,FANK1 |
| 4.657e-02 | -3.07 | GSE7460_CD8_TCELL_VS_TREG_ACT_UP | MSigDB lists | GSE7460_CD8_TCELL_VS_TREG_ACT_UP | 188 | 26 | 17377 | 1707 |
ARHGAP26,EML5,SV2B,SESN2,EVL,PXN,CACNG3,AGPAT4,ELOVL7,RAPGEF4,LRMP,MCTP2,PREX1,KIF21B,FAM174B,SATB1,NEDD4,EPB41L3,SEMA4F,NACC2,GPR160,DSG2,RALGAPA2,SLC9B1,FILIP1,ATP2B4 |
| 4.657e-02 | -3.07 | GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN | 188 | 26 | 17377 | 1707 |
RGS16,GAPDH,SCAMP1,KLHL23,SLC27A2,RECK,REL,RBFOX2,GPR65,RPL21,EPS8,NPM1,PDE8A,ATF3,PLCB1,NEDD4,GLCE,PLS3,ID3,ZNF266,RND3,PRCP,RGS10,GEM,ARL4D,ABCG1 |
| 4.657e-02 | -3.07 | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP | 188 | 26 | 17377 | 1707 |
COL9A3,SIDT1,IL15,GPR65,CAPN5,MCOLN3,HERC6,INPP1,TNKS1BP1,PRRG4,CA13,ISG20,CXCL10,TLR3,SETDB2,GYPC,CSF1,EHD3,GHR,GTF2F2,CMPK2,ZNF365,SLFN5,MED12L,LARP1,PARP9 |
| 4.657e-02 | -3.07 | GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_DN | MSigDB lists | GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_DN | 188 | 26 | 17377 | 1707 |
CREB3L2,ITGB7,TNK2,ARAP2,RHOQ,ALDH2,MPP1,GALNT12,PTPN6,RAPGEF4,CYP4V2,YPEL2,BNIP3L,COBLL1,ATF3,RABAC1,COTL1,LCP2,CD40,PGM2L1,TSPAN13,LRRK1,CERS4,DENND1C,PRKACB,DDIT3 |
| 4.657e-02 | -3.07 | GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP | MSigDB lists | GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP | 188 | 26 | 17377 | 1707 |
CREB3L2,PAK1,TCP11L2,TTC39B,SLC37A1,RNF145,UBASH3B,ZDHHC15,PRKAR2B,ADAMTS6,OTUD1,ARHGAP21,TECPR1,IGIP,GPR155,GAS2L3,FAM107B,RUNDC3B,TSC22D1,PAM,MARCH3,ACVR2A,SFMBT1,FIG4,NRP1,PSPH |
| 4.657e-02 | -3.07 | GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP | MSigDB lists | GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP | 188 | 26 | 17377 | 1707 |
TFCP2L1,GNG12,TTC39B,SH2D2A,TES,PTPN6,LDLR,FHL2,ASS1,MAFB,FNDC3A,LCP2,DHX32,ISG20,CYP51A1,IDI1,HMGCS1,MSMO1,CSF1,EIF1,RGS10,SQLE,GEM,POU2F2,SLC1A5,HMGCR |
| 4.657e-02 | -3.07 | GSE20715_0H_VS_6H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_6H_OZONE_LUNG_UP | 188 | 26 | 17377 | 1707 |
UROS,MPP1,ATOX1,PPFIBP2,BNIP3L,PKP2,WNT11,FAM198B,GRK6,GPSM2,RAB38,C3orf70,TNFRSF19,FGR,DOCK7,PLAGL1,GPRC5B,DACT1,CSF1,RPS11,TOX,UNC5B,RCAN3,SNAI2,FZD1,PCSK6 |
| 4.657e-02 | -3.07 | GSE6674_CPG_VS_PL2_3_STIM_BCELL_DN | MSigDB lists | GSE6674_CPG_VS_PL2_3_STIM_BCELL_DN | 188 | 26 | 17377 | 1707 |
SLC3A2,GARS,MYO10,MCTP2,FHL2,COBLL1,MARS,CHAC1,CHSY1,TMEM170B,FNDC3A,AARS,RNF141,ASNS,MYC,XBP1,ERN1,SLC7A5,HK2,FAM84B,GEM,ERRFI1,PTPRE,RASGRP1,LARP1,LRP12 |
| 4.657e-02 | -3.07 | GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP | 188 | 26 | 17377 | 1707 |
MYCBP2,SLC40A1,MXI1,CELSR1,SKAP2,ZCCHC24,BLVRB,VAMP8,KCTD12,SLC12A6,UCHL3,FAM13A,AMDHD1,C11orf45,TXNRD3,RNF141,NACC2,NCKAP1L,PLXDC2,EIF4EBP1,ERCC5,LMAN2,TMEM37,TLR4,SYK,DCBLD1 |
| 4.657e-02 | -3.07 | GSE7831_UNSTIM_VS_CPG_STIM_PDC_4H_DN | MSigDB lists | GSE7831_UNSTIM_VS_CPG_STIM_PDC_4H_DN | 188 | 26 | 17377 | 1707 |
ITGB7,UROS,ST6GAL1,LDLR,DUSP9,RYR2,SLC25A28,ACVR2B,ZDHHC14,DDR1,BMP6,HERPUD1,GLCE,PLS3,EPCAM,SPNS1,GSN,IGF1R,ZDHHC6,B3GALT2,SVIL,PACSIN1,ETV1,FES,CEBPD,CTNND2 |
| 4.657e-02 | -3.07 | GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_UP | 188 | 26 | 17377 | 1707 |
MICAL2,ITGB7,ST14,REL,STAT4,FHDC1,NFIA,RASA3,NDRG2,PHGDH,PEAK1,COL14A1,AMDHD1,STK24,TMEM53,TIFA,KCNN2,SH3RF1,PLXDC2,AKT3,GHR,VGLL4,PURG,SFN,LARP1,ABCG1 |
| 4.657e-02 | -3.07 | GSE19923_WT_VS_E2A_KO_DP_THYMOCYTE_UP | MSigDB lists | GSE19923_WT_VS_E2A_KO_DP_THYMOCYTE_UP | 188 | 26 | 17377 | 1707 |
EFNB2,LATS2,RAB3B,AVPI1,IL15,TMEM126A,ABCC2,SNAP25,GDPD5,TNFRSF19,SESN1,CBLN1,TTC30B,DDIT4,CCNJ,PLS3,CACHD1,NSD1,LHX6,TNFRSF1A,GSTM3,ST8SIA1,GFI1,CDH2,MID1,CRYL1 |
| 4.657e-02 | -3.07 | GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_DN | MSigDB lists | GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_DN | 188 | 26 | 17377 | 1707 |
CARS,MSX1,IGFBP6,CHCHD7,CRIM1,GCAT,NR4A1,RASD1,ATF3,PHGDH,AARS,HPCAL4,FAM131B,RND2,KIAA1958,TRIB3,EOMES,PLK2,PCBP4,RAI14,DENND1C,TLN2,JAM2,SMAD6,CTH,DUSP1 |
| 4.657e-02 | -3.07 | GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | MSigDB lists | GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | 188 | 26 | 17377 | 1707 |
FER,MYCBP2,STXBP5L,BMPR2,RECK,RAPGEF2,DNAJC6,CALCRL,CTBP2,SLC25A28,GSTO1,RNF24,SLC12A6,HSPA12B,ZNF569,FKBP9,DOCK7,RNF217,HPSE,NCKAP1L,PRCP,ERN1,ZNF704,SGK3,MORN4,GATM |
| 4.658e-02 | -3.07 | membrane assembly | biological process | GO:0071709 | 28 | 6 | 17256 | 1658 |
NLGN4X,NRXN1,PTPRD,MAGI2,CDH2,LRP4 |
| 4.658e-02 | -3.07 | heparan sulfate proteoglycan metabolic process | biological process | GO:0030201 | 28 | 6 | 17256 | 1658 |
HS3ST3B1,HPSE,XYLT1,HS6ST3,GLCE,HS3ST5 |
| 4.658e-02 | -3.07 | positive regulation of mesenchymal cell proliferation | biological process | GO:0002053 | 28 | 6 | 17256 | 1658 |
IRS2,FOXP2,BMPR1A,SHOX2,MYC,FGFR1 |
| 4.658e-02 | -3.07 | regulation of axon extension involved in axon guidance | biological process | GO:0048841 | 28 | 6 | 17256 | 1658 |
SEMA3C,SEMA4F,NRP1,BMPR2,SEMA3A,PLXNA2 |
| 4.658e-02 | -3.07 | histone phosphorylation | biological process | GO:0016572 | 28 | 6 | 17256 | 1658 |
PRKAA2,NEK11,PKN1,PRKCA,PRKCB,PRKCD |
| 4.665e-02 | -3.07 | regulation of protein activation cascade | biological process | GO:2000257 | 50 | 9 | 17256 | 1658 |
CD55,CFH,C4A,CFHR1,CR2,C1R,PROS1,SUSD4,C4BPB |
| 4.665e-02 | -3.07 | response to glucagon | biological process | GO:0033762 | 50 | 9 | 17256 | 1658 |
GNG12,GNB4,SREBF1,ADCY1,ASS1,ADCY6,ABCC2,PRKAR2B,PRKACB |
| 4.665e-02 | -3.07 | positive regulation of muscle contraction | biological process | GO:0045933 | 50 | 9 | 17256 | 1658 |
TRPM4,ITGA2,GSTO1,ABAT,CTTN,OXTR,ENO1,NOS1AP,CHRM3 |
| 4.665e-02 | -3.07 | membrane invagination | biological process | GO:0010324 | 50 | 9 | 17256 | 1658 |
GSN,FCHO2,DOCK1,MSR1,GULP1,FNBP1L,SNX9,RAC3,SPIRE1 |
| 4.668e-02 | -3.06 | vitamin binding | molecular function | GO:0019842 | 138 | 20 | 17224 | 1680 |
GPT2,MOCOS,GCAT,OGDHL,FASN,CBS,ABAT,ETNPPL,LRAT,TPK1,IRX5,FTCDNL1,AADAT,PLOD2,P4HA2,PAM,P4HA1,PHYKPL,CTH,GLDC |
| 4.668e-02 | -3.06 | node of Ranvier | cellular component | GO:0033268 | 15 | 4 | 18223 | 1724 |
SCN2A,KCNQ3,SCN1B,SCN8A |
| 4.669e-02 | -3.06 | SH2DOMAIN | prints domains | PR00401 | 72 | 12 | 4652 | 458 |
FER,VAV3,FGR,INPPL1,SH2D2A,GRB14,PTPN6,SHF,GRB10,FRK,SYK,FES |
| 4.671e-02 | -3.06 | GST_CTER | prosite domains | PS50405 | 32 | 7 | 12060 | 1278 |
GSTM3,MARS,GDAP1,GSTO1,GSTM2,GSTO2,GSTM4 |
| 4.675e-02 | -3.06 | JUN (Jun proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 3725 | 277 | 37 | 17029 | 1718 |
RUNX2,JDP2,ARHGAP22,CEBPA,NTRK3,CREB5,SATB1,NEDD4,SKI,MOK,RPS6KA2,GATA2,MYC,GTF2F2,TFAP2A,BCL6,BEND4,ETV1,ATF4,STAT4,NFE2L1,MAFB,YAP1,SMARCD3,ATF3,SATB2,RACK1,BATF,BATF3,CEBPB,SMAD3,KLF5,HOXD13,TPM1,MAPK10,HOXB9,DDIT3 |
| 4.680e-02 | -3.06 | regulation of protein transport | biological process | GO:0051223 | 645 | 75 | 17256 | 1658 |
EXPH5,PRKN,LGR4,TRIM16,LILRB1,GATA3,CHUK,ITPR2,ABAT,NRXN1,PRKCA,BAG3,UNC13B,SEC16B,TCAF2,KCNS3,MARCKS,MYRIP,TLR4,IL1RAP,RASGRP1,GAPDH,ACVR1C,PFKFB2,WLS,LRRK2,BNIP3L,CD40,SERGEF,IRS2,SMAD3,INSIG1,GBP1,PAM,DISP1,ATG5,TNFSF4,TENM1,STXBP5L,C1QTNF3,FN1,IPO5,APBB1,UBAC2,ARL2,GAS6,NDFIP2,BMP6,MCU,NKX6-1,RAB11FIP5,PRKCD,SREBF1,PCK2,SYK,HMGCR,VEGFC,TRPM4,PAK1,ATP5IF1,CACNA1E,SYBU,RAPGEF4,RACK1,SNAP25,TLR6,ZIC1,GPLD1,FGR,ICA1,XBP1,BMP4,PKIA,SFN,STOM |
| 4.685e-02 | -3.06 | GO_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS | MSigDB lists | GO_UNSATURATED_FATTY_ACID_METABOLIC_PROCESS | 104 | 16 | 17377 | 1707 |
PLA2G4A,DAGLA,MAPKAPK2,FADS1,ACSL1,ALOX5AP,CYP2J2,FAAH2,ELOVL3,TNFRSF1A,HPGD,SCD,CYP2U1,SYK,PTGES,CYP1B1 |
| 4.685e-02 | -3.06 | MODULE_157 | MSigDB lists | MODULE_157 | 104 | 16 | 17377 | 1707 |
RGS16,MVK,SLC6A9,PTPRU,STAT4,EFNA3,ABAT,SMPDL3B,KCNJ4,FGR,MPP2,STXBP1,RAPGEF5,MME,CNTN1,MEF2C |
| 4.685e-02 | -3.06 | GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_AMINOGLYCAN_BIOSYNTHETIC_PROCESS | 104 | 16 | 17377 | 1707 |
UST,CHSY3,GCNT2,UGDH,XYLT1,SDC3,CHSY1,BCAN,GPC6,GLCE,HS3ST5,DSEL,HS3ST3B1,B4GALT7,PDGFRB,B4GALT6 |
| 4.689e-02 | -3.06 | HATADA_METHYLATED_IN_LUNG_CANCER_UP | MSigDB lists | HATADA_METHYLATED_IN_LUNG_CANCER_UP | 365 | 46 | 17377 | 1707 |
LRFN5,STOX2,ZCCHC24,ARHGAP22,BEGAIN,GATA3,PRDM8,ISYNA1,TNFRSF10C,CANX,KCNC4,COL14A1,TBC1D30,SPIRE1,SYDE2,GBGT1,TYMP,ALDOC,SCARF2,TFAP2A,DAB2IP,SYNGR3,PLTP,TSHR,SLIT2,RASGRP1,BOD1,NOS3,RNF152,NECAB1,ANK2,RAPGEF4,JPH1,ST6GALNAC3,LHPP,PYGO1,RARRES2,SLC46A3,ADAMTS17,DYRK1B,CSF1,PAM,SVIL,HOXD13,PAX9,TLL2 |
| 4.694e-02 | -3.06 | Toxicity of botulinum toxin type A (BoNT/A) | REACTOME pathways | R-HSA-5250968 | 4 | 2 | 10287 | 971 |
SV2B,SNAP25 |
| 4.694e-02 | -3.06 | Transcriptional activation of cell cycle inhibitor p21 | REACTOME pathways | R-HSA-69895 | 4 | 2 | 10287 | 971 |
PCBP4,ZNF385A |
| 4.694e-02 | -3.06 | Cholesterol biosynthesis via lathosterol | REACTOME pathways | R-HSA-6807062 | 4 | 2 | 10287 | 971 |
DHCR7,DHCR24 |
| 4.694e-02 | -3.06 | Cholesterol biosynthesis via desmosterol | REACTOME pathways | R-HSA-6807047 | 4 | 2 | 10287 | 971 |
DHCR7,DHCR24 |
| 4.694e-02 | -3.06 | Transcriptional activation of p53 responsive genes | REACTOME pathways | R-HSA-69560 | 4 | 2 | 10287 | 971 |
PCBP4,ZNF385A |
| 4.694e-02 | -3.06 | Regulation of Commissural axon pathfinding by Slit and Robo | REACTOME pathways | R-HSA-428542 | 4 | 2 | 10287 | 971 |
ROBO2,SLIT2 |
| 4.694e-02 | -3.06 | NGF processing | REACTOME pathways | R-HSA-167060 | 4 | 2 | 10287 | 971 |
PCSK6,PCSK5 |
| 4.695e-02 | -3.06 | HENDRICKS_SMARCA4_TARGETS_DN | MSigDB lists | HENDRICKS_SMARCA4_TARGETS_DN | 49 | 9 | 17377 | 1707 |
ID3,ASNS,LGALS3,CKAP2,MYC,HPGD,PLS1,NRP1,SPRY2 |
| 4.695e-02 | -3.06 | GO_MECHANORECEPTOR_DIFFERENTIATION | MSigDB lists | GO_MECHANORECEPTOR_DIFFERENTIATION | 49 | 9 | 17377 | 1707 |
NTRK3,ATOH1,BMP4,FAT4,PDZD7,GABRB2,FGFR1,MCOLN3,PLS3 |
| 4.695e-02 | -3.06 | GO_FACE_DEVELOPMENT | MSigDB lists | GO_FACE_DEVELOPMENT | 49 | 9 | 17377 | 1707 |
MSX1,ARID5B,LRP6,PLEKHA1,PAX9,ASPH,CRISPLD1,SKI,DKK1 |
| 4.696e-02 | -3.06 | OKUMURA_INFLAMMATORY_RESPONSE_LPS | MSigDB lists | OKUMURA_INFLAMMATORY_RESPONSE_LPS | 171 | 24 | 17377 | 1707 |
ACSL1,RUNX2,CLGN,SLC27A2,REL,GALNT12,DNAJC6,ATP11A,RAB38,ZFPM2,SMAD3,SLC7A11,AKT3,RAB31,PAM,MAOA,ACTA2,GULP1,MARCKS,WWC2,TNFSF4,MAST4,RASGRP1,CEBPD |
| 4.697e-02 | -3.06 | transforming growth factor beta receptor signaling pathway | biological process | GO:0007179 | 98 | 15 | 17256 | 1658 |
SMAD3,CGN,GCNT2,PXN,ID1,ACVR1,TGFBR3,SMAD9,MSTN,FERMT2,HPGD,BMPR1A,SMAD6,ZFYVE9,SKI |
| 4.700e-02 | -3.06 | BROWNE_HCMV_INFECTION_6HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_6HR_DN | 154 | 22 | 17377 | 1707 |
MN1,TRIM2,TDRD3,ITGA6,ARID5B,PRKAR2B,CREB5,DSP,GAS1,DKK1,SMAD3,ATPAF2,ICA1,FRY,RND3,FAM168A,ITGB3,SGK1,NAP1L3,FBXL2,ETV1,TBC1D8 |
| 4.700e-02 | -3.06 | AAGGGAT,MIR-188 | MSigDB lists | AAGGGAT,MIR-188 | 72 | 12 | 17377 | 1707 |
BCL11B,EFNB2,CGN,KPNA3,KLF12,NBEA,MAFB,PHACTR2,IGF2BP2,FAM117B,IL13RA1,MEF2C |
| 4.700e-02 | -3.06 | GO_CELLULAR_GLUCOSE_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_GLUCOSE_HOMEOSTASIS | 72 | 12 | 17377 | 1707 |
IRS2,RAB11FIP5,RANBP2,SESN2,FN1,XBP1,ERN1,HK2,PTPRN2,HK1,GAS6,PPARGC1A |
| 4.700e-02 | -3.06 | CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_POLYSOMY7_UP | 72 | 12 | 17377 | 1707 |
ADAMTS17,CHN2,ICA1,SLC16A2,MFSD2A,PEMT,RAPGEF4,ADCY1,TUBE1,CHAC1,ADSSL1,COBL |
| 4.700e-02 | -3.06 | RODRIGUES_THYROID_CARCINOMA_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_DN | 72 | 12 | 17377 | 1707 |
MYO1D,PHLDB2,FN1,PMEPA1,MAP2,SHANK2,BBC3,IGF2BP2,CREB5,PLCB1,SLIT2,DCBLD2 |
| 4.700e-02 | -3.06 | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | MSigDB lists | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | 72 | 12 | 17377 | 1707 |
PRAME,COL9A3,RHOD,CAP2,SHANK2,COL4A5,ISYNA1,SEZ6L2,APBA2,KBTBD11,RAC3,SEMA6A |
| 4.715e-02 | -3.05 | RPL7A (ribosomal protein L7a) | protein interactions | 6130 | 175 | 25 | 17029 | 1718 |
RPS20,PRKN,RPL26,LGALS3,FN1,NOP53,RPL21,YAP1,NPM1,CTBP2,RACK1,RPL13A,RPL34,RPL12,EEF2,RPL28,BHLHA15,RPS11,ACTA2,RPL4,RPS12,RPL26L1,SFN,RPS23,RPS13 |
| 4.715e-02 | -3.05 | alphav-beta3 integrin-IGF-1-IGF1R complex | cellular component | GO:0035867 | 4 | 2 | 18223 | 1724 |
IGF1R,ITGB3 |
| 4.715e-02 | -3.05 | integral component of postsynaptic specialization membrane | cellular component | GO:0099060 | 4 | 2 | 18223 | 1724 |
PTPRS,CDH2 |
| 4.715e-02 | -3.05 | multivesicular body, internal vesicle | cellular component | GO:0097487 | 4 | 2 | 18223 | 1724 |
LAPTM4B,LRRK2 |
| 4.715e-02 | -3.05 | phosphopyruvate hydratase complex | cellular component | GO:0000015 | 4 | 2 | 18223 | 1724 |
ENO2,ENO1 |
| 4.715e-02 | -3.05 | intrinsic component of postsynaptic specialization membrane | cellular component | GO:0098948 | 4 | 2 | 18223 | 1724 |
PTPRS,CDH2 |
| 4.715e-02 | -3.05 | Wnt-Frizzled-LRP5/6 complex | cellular component | GO:1990851 | 4 | 2 | 18223 | 1724 |
LRP6,FZD8 |
| 4.715e-02 | -3.05 | GAIT complex | cellular component | GO:0097452 | 4 | 2 | 18223 | 1724 |
GAPDH,RPL13A |
| 4.717e-02 | -3.05 | Chondroitin sulfate/dermatan sulfate metabolism | REACTOME pathways | R-HSA-1793185 | 51 | 9 | 10287 | 971 |
UST,CHSY3,XYLT1,SDC3,DSEL,CHSY1,BCAN,B4GALT7,GPC6 |
| 4.726e-02 | -3.05 | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | 622 | 74 | 17377 | 1707 |
CREB3L2,LDLR,CHUK,DDR1,SLC19A2,FKBP11,TGFBR3,TM9SF2,PPFIBP1,TMEM86A,STEAP3,TMED9,SERPINH1,PDGFRB,ERGIC1,TMEM43,ATP10D,FGFR1,DCBLD2,GJC1,SPNS1,SLC39A14,ZNF266,GPRC5B,P4HA2,LAMB1,BMP1,P4HA1,PTPRS,ANO10,MRC2,IGFBP6,ITPRIP,CD276,UBAC2,SCD,COL4A5,CHSY1,NDFIP2,NEO1,IGF1R,MGAT1,MSMO1,STC2,GAS2L3,SREBF1,ADCY6,LMAN2,NCAM1,TSPAN9,CKAP4,LRP12,DUSP1,HMGCR,IL17RD,QSOX1,SLC36A1,ATP11A,BAIAP2,CTIF,HEG1,TMCO3,RPL12,MYADM,CLDN12,CSF1,QPCTL,SRD5A3,SLC7A5,SQLE,LAPTM4B,PTGES,DIRC2,DCBLD1 |
| 4.728e-02 | -3.05 | leukocyte migration | biological process | GO:0050900 | 300 | 38 | 17256 | 1658 |
CXCR5,LGALS3,FN1,GRB14,ITGA6,EPS8,SELL,JCHAIN,GATA3,ADD2,STAT5B,GAS6,MCOLN2,EPCAM,GPR15,SLC7A11,ITGB3,PDE4D,PROS1,JAM2,TNFRSF11A,SYK,DOCK8,TRPM4,VAV3,ITGB7,FER,SLC3A2,PODXL2,PTPN6,PREX1,SDC3,ATP1B1,JAM3,CXCL10,GYPC,NCKAP1L,SLC7A5 |
| 4.731e-02 | -3.05 | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | 96 | 15 | 17377 | 1707 |
FGFR4,TRIB3,PDE1B,NR4A1,AKT3,PRKCD,ADCY1,ADCY6,CHUK,PRKAR2B,FGF17,ITPR2,PRKCA,FGFR1,PRKACB |
| 4.735e-02 | -3.05 | GO_CELL_FATE_COMMITMENT | MSigDB lists | GO_CELL_FATE_COMMITMENT | 223 | 30 | 17377 | 1707 |
BCL11B,PTCH2,LATS2,ACVR1,RUNX2,FGF13,GATA3,SATB2,WNT11,NTRK3,PRDM1,ATOH1,BATF,CHD5,GAS1,TRPS1,NKX6-1,CEBPB,DOCK7,EOMES,GATA2,ZNF521,DLX2,BMP4,NRP1,SPRY2,SIX2,FOXA1,NKX2-1,MEF2C |
| 4.735e-02 | -3.05 | AAGCACT,MIR-520F | MSigDB lists | AAGCACT,MIR-520F | 223 | 30 | 17377 | 1707 |
SLC6A9,COL4A3,RASAL2,PLAG1,XYLT1,VLDLR,PRDM8,CREB5,ZFPM2,FNDC3A,NOVA1,MBNL2,PPP2R3A,MTUS1,CAMK2N1,RALGPS2,BACH2,FRAS1,LHX6,TOX,FIGN,VASH2,IQSEC2,CDH2,ZNF385A,MED12L,PRKACB,GAB2,MEF2C,PGBD5 |
| 4.736e-02 | -3.05 | G Protein Signaling Pathways | WikiPathways | WP35 | 96 | 16 | 5312 | 569 |
GNG12,PDE1B,PRKCB,AKAP5,AKAP7,GNAO1,PRKCD,ADCY1,ADCY6,PRKCQ,PRKAR2B,PDE8A,PDE4D,PRKCA,PRKACB,GNAI1 |
| 4.743e-02 | -3.05 | phosphoprotein phosphatase activity | molecular function | GO:0004721 | 181 | 25 | 17224 | 1680 |
PPP1R3D,SSH3,DUSP8,PTPRU,PTPRD,PTPN6,PTPN13,UBASH3B,PTPN21,DNAJC6,PLPP2,DUSP9,LHPP,EYA4,PTPRC,PPM1E,PTPRJ,CDC14B,PALD1,DUSP19,PTPRN2,PTPRS,PPP2R2B,PTPRE,DUSP1 |
| 4.747e-02 | -3.05 | GO_BETA_CATENIN_BINDING | MSigDB lists | GO_BETA_CATENIN_BINDING | 80 | 13 | 17377 | 1707 |
SMAD3,TCF7L1,PXN,PTPRJ,PTPRU,DACT1,RGS20,GRIP1,CBY1,CDH2,CTNND2,MED12L,BTRC |
| 4.747e-02 | -3.05 | MODULE_481 | MSigDB lists | MODULE_481 | 80 | 13 | 17377 | 1707 |
TLR3,LGR4,GRB14,BACE2,SLC36A1,CFHR1,SEMA3C,F12,CDH2,THSD1,IL1RAP,PPP2R3A,CACNA2D1 |
| 4.749e-02 | -3.05 | positive regulation of protein serine/threonine kinase activity | biological process | GO:0071902 | 355 | 44 | 17256 | 1658 |
TENM1,TNIK,NEK10,ACSL1,AVPI1,FZD8,NTRK3,PKN1,TPD52L1,STK24,TLR3,GHR,INAVA,DAB2IP,IQGAP3,TLR4,TNFRSF11A,SYK,SPRY2,RASGRP1,PDGFRB,PAK1,FZD4,TGFA,RAPGEF2,LRRK2,DUSP9,CD40,TLR6,FGFR1,SNCA,DKK1,MAPKAPK2,MAP2K6,ERN1,MAP3K21,DUSP19,TNFSF15,HGF,DIRAS1,BMP4,MAPK10,MAP3K20,ATP2B4 |
| 4.751e-02 | -3.05 | GO_REGULATION_OF_ENDOCYTOSIS | MSigDB lists | GO_REGULATION_OF_ENDOCYTOSIS | 197 | 27 | 17377 | 1707 |
TNK2,LGALS3,C4A,DNAJC6,OPHN1,PACSIN3,LILRB1,HIP1,BTBD9,SYNJ2BP,GAS6,DOCK2,C4BPB,SNCA,DKK1,FGR,SH3GL2,NCKAP1L,GATA2,ITGA2,LMAN2,PROS1,PLD1,PACSIN1,MAGI2,SYK,STON2 |
| 4.753e-02 | -3.05 | transaminase activity | molecular function | GO:0008483 | 21 | 5 | 17224 | 1680 |
GPT2,PHYKPL,ABAT,AADAT,ETNPPL |
| 4.753e-02 | -3.05 | chemorepellent activity | molecular function | GO:0045499 | 21 | 5 | 17224 | 1680 |
SEMA3C,NRG3,SEMA4F,SEMA3A,FLRT3 |
| 4.753e-02 | -3.05 | cellular nitrogen compound catabolic process | biological process | GO:0044270 | 457 | 55 | 17256 | 1658 |
RPS20,NUDT10,ADAL,PDE1B,ENO2,BLVRB,TNKS1BP1,NUDT12,RPL13A,QPRT,RPL34,TYMP,PRTFDC1,AADAT,KMO,MGAT1,ALDOC,PDE10A,RPS11,ALDH1L1,PDE4D,ENO1,ZFP36L2,RPS23,SMPDL3A,RPS13,RPL26,GAPDH,PNP,PNRC1,PFKFB2,ALDH1L2,RPL21,OGDHL,PDE8A,AGO4,EXOG,AMDHD1,ISG20,CTIF,ENTPD1,ENPP1,RPL12,RPL28,TDO2,CECR2,ENTPD7,ALDOA,ERN1,HK2,PGM2L1,RPL4,HK1,RPS12,NUDT17 |
| 4.754e-02 | -3.05 | WNT_SIGNALING | MSigDB lists | WNT_SIGNALING | 88 | 14 | 17377 | 1707 |
TCF7L1,GAPDH,FZD4,MYC,FZD8,LRP6,CTBP2,WNT11,PYGO1,KREMEN1,BTRC,RPL13A,FZD1,DKK1 |
| 4.754e-02 | -3.05 | GO_AXIS_SPECIFICATION | MSigDB lists | GO_AXIS_SPECIFICATION | 88 | 14 | 17377 | 1707 |
EPB41L5,SETDB2,WLS,RGS20,LRP6,BMPR1A,BMP4,SMAD6,COBL,PGAP1,DDIT3,SIX2,SKI,PCSK6 |
| 4.754e-02 | -3.05 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0090092 | 228 | 30 | 17256 | 1658 |
NBL1,MSX1,ACVR1,BMPR2,MSTN,RASL11B,ACVR2B,BMP6,SKI,DKK1,NEO1,SMAD3,INHBC,TGFBR3,PMEPA1,FBN1,DACT1,RBPMS2,WWTR1,INHBE,CHRDL1,ACVR2A,BMPR1A,BMP4,SPART,SMAD6,MAGI2,PCSK6,FZD1,NKX2-1 |
| 4.765e-02 | -3.04 | LGALS9 (galectin 9) | protein interactions | 3965 | 78 | 13 | 17029 | 1718 |
MRC2,PTPRJ,LGALS3,FN1,NCR3LG1,CD276,LAMB1,SLC12A6,SLC1A5,MET,KIAA1549,ATP2B4,IGSF3 |
| 4.770e-02 | -3.04 | lipid metabolic process | biological process | GO:0006629 | 1235 | 136 | 17256 | 1658 |
MVK,ACSL1,UGT8,PLBD2,LDLR,STAT5B,CEBPA,ABHD6,ABHD4,CYP51A1,FAAH2,TMEM86A,SERINC2,PLTP,PDGFRB,NKX2-1,CYP1B1,SESN2,GDPD1,PLPP2,NFE2L1,HACD1,PRKAR2B,FGF17,PLEKHA1,GPC6,INSIG1,ENPP6,BDH2,TNFRSF1A,B3GALT2,INPP5F,PIK3C2B,PPARGC1A,CRYL1,PRKAA2,INPPL1,ALOX5AP,EHHADH,CYP2J2,OLAH,DHCR24,ELOVL7,CYP4V2,SCD,ISYNA1,PGAP1,GBGT1,PIK3AP1,MSMO1,SREBF1,ST8SIA1,FAR2,NCEH1,HMGCR,FADS1,FGFR4,PLEKHA8,SLC27A2,MGST3,VLDLR,FASN,SDC3,ST6GALNAC3,AIG1,NPC2,PLCB1,DAGLA,MFSD2A,PTPRN2,SQLE,PLD1,DHCR7,OSBPL6,ACSM3,TFCP2L1,PLA2G4A,BTC,ELOVL4,LPCAT2,LPIN3,CYP26A1,CDS1,PLPP1,ERG28,IDI1,FABP6,MET,ALG10B,HRASLS,B3GALT1,EBPL,MVD,CYB5R2,RARRES2,ETNPPL,FGFR1,SNCA,IRS2,PEMT,INPP4B,PAM,ALG11,HPGD,HGF,CYP2U1,MBOAT2,SERINC5,INPP1,GDPD5,HMGCS1,SOAT2,GHR,CERS4,FIG4,PCK2,SMPDL3A,B4GALT6,CES3,GSTM2,AGPAT4,PTPN13,ELOVL3,LEPR,LRAT,SMPDL3B,GPLD1,PLPPR2,ACER2,XBP1,SRD5A3,OSBPL5,PIP5KL1,CERS1,PTGES,ABCG1 |
| 4.780e-02 | -3.04 | DEP | pfam domains | PF00610 | 21 | 5 | 17054 | 1666 |
RGS7,GPR155,RAPGEF4,PREX1,DEPTOR |
| 4.782e-02 | -3.04 | synaptic vesicle docking | biological process | GO:0016081 | 9 | 3 | 17256 | 1658 |
SNAP25,UNC13B,SNPH |
| 4.782e-02 | -3.04 | retina vasculature morphogenesis in camera-type eye | biological process | GO:0061299 | 9 | 3 | 17256 | 1658 |
NRP1,FZD4,CYP1B1 |
| 4.782e-02 | -3.04 | negative regulation of excitatory postsynaptic potential | biological process | GO:0090394 | 9 | 3 | 17256 | 1658 |
NLGN4X,CBLN1,LRRK2 |
| 4.782e-02 | -3.04 | cellular response to leucine | biological process | GO:0071233 | 9 | 3 | 17256 | 1658 |
SESN2,SESN1,RRAGD |
| 4.782e-02 | -3.04 | insulin metabolic process | biological process | GO:1901142 | 9 | 3 | 17256 | 1658 |
CPE,ERO1B,ERN1 |
| 4.782e-02 | -3.04 | purine ribonucleoside catabolic process | biological process | GO:0046130 | 9 | 3 | 17256 | 1658 |
ADAL,PRTFDC1,PNP |
| 4.782e-02 | -3.04 | contact inhibition | biological process | GO:0060242 | 9 | 3 | 17256 | 1658 |
YAP1,PAK1,PTPRJ |
| 4.782e-02 | -3.04 | multicellular organismal iron ion homeostasis | biological process | GO:0060586 | 9 | 3 | 17256 | 1658 |
SLC40A1,BTBD9,BMP6 |
| 4.782e-02 | -3.04 | positive regulation of protein homooligomerization | biological process | GO:0032464 | 9 | 3 | 17256 | 1658 |
HRK,RACK1,BIK |
| 4.782e-02 | -3.04 | positive regulation of phagocytosis, engulfment | biological process | GO:0060100 | 9 | 3 | 17256 | 1658 |
NCKAP1L,GATA2,ITGA2 |
| 4.782e-02 | -3.04 | regulation of tubulin deacetylation | biological process | GO:0090043 | 9 | 3 | 17256 | 1658 |
BEX4,PRKAA2,FRY |
| 4.782e-02 | -3.04 | regulation of mesodermal cell differentiation | biological process | GO:1905770 | 9 | 3 | 17256 | 1658 |
BMPR1A,FGFR1,DKK1 |
| 4.782e-02 | -3.04 | negative regulation of activin receptor signaling pathway | biological process | GO:0032926 | 9 | 3 | 17256 | 1658 |
ACVR1,MAGI2,SKI |
| 4.782e-02 | -3.04 | L-serine transport | biological process | GO:0015825 | 9 | 3 | 17256 | 1658 |
SERINC5,SLC1A5,SERINC2 |
| 4.782e-02 | -3.04 | positive regulation of synapse maturation | biological process | GO:0090129 | 9 | 3 | 17256 | 1658 |
DAB2IP,NRXN1,ADGRL1 |
| 4.782e-02 | -3.04 | cranial nerve formation | biological process | GO:0021603 | 9 | 3 | 17256 | 1658 |
MAFB,HOXA1,TFAP2A |
| 4.782e-02 | -3.04 | heart field specification | biological process | GO:0003128 | 9 | 3 | 17256 | 1658 |
SMARCD3,BMP4,MEF2C |
| 4.782e-02 | -3.04 | secondary heart field specification | biological process | GO:0003139 | 9 | 3 | 17256 | 1658 |
SMARCD3,BMP4,MEF2C |
| 4.782e-02 | -3.04 | cellular response to purine-containing compound | biological process | GO:0071415 | 9 | 3 | 17256 | 1658 |
RYR2,GSTM2,PPARGC1A |
| 4.782e-02 | -3.04 | positive regulation of voltage-gated calcium channel activity | biological process | GO:1901387 | 9 | 3 | 17256 | 1658 |
CACNB2,EHD3,CACNA2D1 |
| 4.782e-02 | -3.04 | purine nucleoside catabolic process | biological process | GO:0006152 | 9 | 3 | 17256 | 1658 |
ADAL,PRTFDC1,PNP |
| 4.782e-02 | -3.04 | proline transport | biological process | GO:0015824 | 9 | 3 | 17256 | 1658 |
SLC36A4,SLC6A15,SLC36A1 |
| 4.782e-02 | -3.04 | SA node cell to atrial cardiac muscle cell communication | biological process | GO:0086070 | 9 | 3 | 17256 | 1658 |
SCN5A,ANK2,GJC1 |
| 4.782e-02 | -3.04 | thyroid hormone transport | biological process | GO:0070327 | 9 | 3 | 17256 | 1658 |
ABCC2,SLC16A2,SLC16A10 |
| 4.782e-02 | -3.04 | cellular response to manganese ion | biological process | GO:0071287 | 9 | 3 | 17256 | 1658 |
PRKN,ATF4,LRRK2 |
| 4.782e-02 | -3.04 | embryonic foregut morphogenesis | biological process | GO:0048617 | 9 | 3 | 17256 | 1658 |
SMAD3,EPB41L5,ACVR2B |
| 4.782e-02 | -3.04 | positive regulation of sphingolipid biosynthetic process | biological process | GO:0090154 | 9 | 3 | 17256 | 1658 |
RACK1,PRKCD,TNFRSF1A |
| 4.782e-02 | -3.04 | positive regulation of ceramide biosynthetic process | biological process | GO:2000304 | 9 | 3 | 17256 | 1658 |
RACK1,PRKCD,TNFRSF1A |
| 4.782e-02 | -3.04 | regulation of systemic arterial blood pressure by norepinephrine-epinephrine | biological process | GO:0001993 | 9 | 3 | 17256 | 1658 |
PDE4D,TPM1,ADRB1 |
| 4.782e-02 | -3.04 | positive regulation of membrane invagination | biological process | GO:1905155 | 9 | 3 | 17256 | 1658 |
NCKAP1L,GATA2,ITGA2 |
| 4.782e-02 | -3.04 | regulation of glial cell apoptotic process | biological process | GO:0034350 | 9 | 3 | 17256 | 1658 |
GAS6,PRKCA,PRKCD |
| 4.782e-02 | -3.04 | galactolipid metabolic process | biological process | GO:0019374 | 9 | 3 | 17256 | 1658 |
UGT8,B3GALT1,B3GALT2 |
| 4.791e-02 | -3.04 | FA | smart domains | SM01195 | 13 | 4 | 9493 | 1056 |
EPB41L5,EPB41L3,FARP1,FRMD5 |
| 4.795e-02 | -3.04 | V$ATF3_Q6 | MSigDB lists | V$ATF3_Q6 | 232 | 31 | 17377 | 1707 |
PHACTR3,CCDC148,PNRC1,PTPRU,AGPAT4,BNIP3L,TJP1,PNMA6A,ATF3,CREB5,PLEKHA1,SEZ6L2,RNF44,TNFRSF19,MBNL2,MAP1B,SPEG,CD37,ICA1,KCNN2,EEF2,PPFIBP1,FLRT3,EIF1,BCL6,KLF9,RPL4,GEM,ATG5,PPARGC1A,DUSP1 |
| 4.800e-02 | -3.04 | human chr4q26 | chromosome location | human chr4q26 | 27 | 5 | 26185 | 1967 |
UGT8,SYNPO2,SEC24D,PRSS12,TRAM1L1 |
| 4.800e-02 | -3.04 | human chr14q22.1 | chromosome location | human chr14q22.1 | 27 | 5 | 26185 | 1967 |
FERMT2,TRIM9,ATL1,SAV1,GPR137C |
| 4.806e-02 | -3.04 | GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 1738 | 191 | 17377 | 1707 |
THOC5,ACVR1,LGR4,TRIM16,DNAJC3,LDLR,GATA3,LILRB1,ASS1,NPM1,CTBP2,CEBPA,STAT5B,PRKCA,IKZF2,ABHD6,NOS1AP,TRPS1,SKI,EPCAM,EOMES,GRHL1,TLR4,TSHR,ETV1,POU3F3,PDGFRB,NKX2-1,MEIS2,ATF4,SMAD9,NR6A1,CAP2,NFIA,NFE2L1,MEF2B,YAP1,SAV1,BATF,AHRR,DYRK1B,KLF12,INSIG1,NCOA7,TNFRSF1A,ADRB1,DLX2,PPARGC1A,NEUROG2,MEF2C,BCL11B,RUNX2,ITGA6,ZIC2,MECOM,ZBTB38,IGF1R,EEF2,GATA2,MYC,SREBF1,EBF4,LRP6,ADCY6,GRIP1,GLIS1,PRR16,BARX1,GPR161,CAND2,CEBPD,NOS3,FGFR4,RAX,MID2,RHOQ,MSTN,ARID5B,FHL2,CALCRL,SMARCD3,MAFB,PLCB1,CPEB1,MAPKAPK2,PLAGL1,HEYL,HOXD13,NKX2-8,TESC,SMYD3,SIX2,CREB3L2,PLA2G4A,ZNF516,SORBS1,IL15,AKAP5,GPR65,OTX1,CHUK,LPIN3,TLR3,ACVR2A,DAB2IP,POU2F2,MET,CTH,FZD1,GLI1,FER,FZD4,ADCY1,WNT11,ATF3,PRKCQ,SATB2,ATOH1,PYGO1,CD40,ASPH,BCL11A,SNCA,SMAD3,IRS2,ZNF711,CXCL10,IKZF3,TRIM34,PRKCB,WFS1,PEMT,WWTR1,ITGA2,KLF5,HGF,DBP,BMPR1A,HOXB9,HEY1,BMPR2,EDA2R,CKAP2,ARHGEF11,REL,CD276,PLAG1,FZD8,APBB1,CREB5,OVOL2,P2RY1,BMP6,NKX6-1,BHLHA15,PRKCD,TFAP2A,GTF2F2,AFAP1L2,MYO6,TNFRSF11A,SLC45A3,SYK,MED12L,MICAL2,SLC40A1,MSX1,NR4A1,ESRRG,ZFPM2,GUCY1A2,SKAP1,TLR6,GPLD1,ZIC1,RERE,CEBPB,EBF1,NSD1,DDAH1,TERT,MAP2K6,XBP1,PAX9,BMP4,SHOX2,FOXA1,BTRC,LARP1,DDIT3,ABCG1 |
| 4.811e-02 | -3.03 | negative regulation of protein depolymerization | biological process | GO:1901880 | 58 | 10 | 17256 | 1658 |
GSN,PLEKHH2,FGF13,CKAP2,EPS8,ADD2,HDGFL3,TMOD2,MID1,SCIN |
| 4.812e-02 | -3.03 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_UP | 180 | 25 | 17377 | 1707 |
RIN2,RGS16,PAGE1,ACSL1,CRIM1,STAT4,AGPAT4,CYB5R2,MYO1B,AK4,PDE8A,BATF,TBC1D30,F3,PMAIP1,ENTPD7,TECPR2,XBP1,SLC2A6,GRIP1,MARCKS,SMPDL3A,IGSF3,LAMP3,HEY1 |
| 4.812e-02 | -3.03 | GO_RESPONSE_TO_KETONE | MSigDB lists | GO_RESPONSE_TO_KETONE | 180 | 25 | 17377 | 1707 |
PRKAA2,FN1,MSTN,GJB2,ADCY1,ASS1,NTRK3,GAS6,GNAI1,FBXO32,TGFBR3,DSG2,GHR,SREBF1,ADCY6,KLF9,OXTR,BMP4,ERRFI1,TNFSF4,SMYD3,SLIT2,ATP2B1,PSPH,DUSP1 |
| 4.812e-02 | -3.03 | GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP | MSigDB lists | GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP | 180 | 25 | 17377 | 1707 |
MPZL3,MICAL2,FN1,ARL15,MVD,LDLR,FASN,PKP2,NDRG2,ISYNA1,SLC7A2,P2RY1,CD40,PCLO,IL17D,ABLIM1,SLC30A4,MCF2L,PRKCD,GULP1,KLF9,SLC1A5,SHOX2,RASGRP1,IGSF3 |
| 4.812e-02 | -3.03 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | 180 | 25 | 17377 | 1707 |
ARAP2,ZNF395,PTPN6,XYLT1,RPL21,LILRB1,CR2,HERC6,SATB1,DENND3,JAM3,PTPRC,FGR,MYADM,SEMA4F,RPL28,KIAA0355,MYC,GNB4,OPN3,PLEKHG1,TSPAN13,HK1,RCAN3,ZNF518B |
| 4.812e-02 | -3.03 | GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_DN | 180 | 25 | 17377 | 1707 |
MN1,BCL7A,MYCBP2,PLEKHA8,UBASH3B,LRRCC1,SPATA13,ZDHHC15,BNIP3L,RNF125,PRKAR2B,ZDHHC14,SNX9,BBS9,SLC46A3,SLCO3A1,STK24,RNF141,RTN1,ZNF362,DOCK7,FAM107B,RUNDC3B,LRRK1,NCEH1 |
| 4.818e-02 | -3.03 | SYK (spleen associated tyrosine kinase) | protein interactions | 6850 | 134 | 20 | 17029 | 1718 |
SH3BP2,PXN,TUBA1A,SH2D2A,UBASH3B,PTPN6,PRKCA,LCP2,NEDD4,SNCA,FGR,TLR3,TENT5A,PIK3AP1,ITGB3,TNFRSF1A,CTTN,TLR4,SYK,GAB2 |
| 4.820e-02 | -3.03 | chondroitin sulfate biosynthesis | BIOCYC pathways | META_PWY-6569 | 18 | 5 | 902 | 105 |
CHSY3,UST,CHSY1,B4GALT7,XYLT1 |
| 4.825e-02 | -3.03 | RNA polymerase II transcription factor activity, sequence-specific DNA binding | molecular function | GO:0000981 | 1624 | 178 | 17224 | 1680 |
GATA3,STAT5B,CEBPA,IKZF2,DACH2,TRPS1,SKI,IKZF5,EOMES,GRHL1,DLX6,ETV1,ENO1,ZBED9,POU3F3,ZNF391,NKX2-1,KCNIP3,ATF4,MEIS2,SMAD9,NR6A1,NFIA,ZNF565,NFE2L1,MEF2B,BATF,ZNF788P,AHRR,TCF7L1,ZNF266,HLF,KLF12,ZBTB20,DLX2,NEUROG2,ZBED8,MLLT3,MEF2C,BCL11B,KLF8,RUNX2,ZNF395,ZHX3,ZNF25,JDP2,GTF2IRD1,SETBP1,ZNF215,ZIC2,SATB1,FOXG1,MECOM,KIAA1958,ZBTB38,ZNF354A,ZNF440,GATA2,MYC,ZIC5,SREBF1,EBF4,ZNF518B,GLIS1,BARX1,ZNF385A,CEBPD,ZNF629,RAX,STAT4,ARID5B,ZNF605,NSD2,MAFB,PRDM1,TAF4B,ZNF558,PLAGL1,HEYL,HOXD13,NKX2-8,SIX2,CREB3L2,TFCP2L1,ID1,ZNF516,ZNF311,OTX1,ZNF83,BCL6B,SP8,ZSCAN5A,ZNF362,ZNF438,POU5F1B,LHX6,BCL6,ZNF521,POU2F2,ZNF460,MYT1,KIAA1549,SP140L,SNAI2,GLI1,SOX21,NKX3-2,PRDM13,SATB2,ATF3,ATOH1,ZNF618,BATF3,BCL11A,ZNF569,ZNF711,ZNF396,SMAD3,MSC,ZNF93,IKZF3,BACH2,ZNF697,SOHLH2,KLF5,BMPR1A,DBP,HOXB9,NR3C2,PURG,ZNF701,HEY1,MXI1,REL,PLAG1,PRDM8,CREB5,OVOL2,ZNF219,HOPX,NKX6-1,FOXP2,IRX5,BHLHA15,TFAP2A,TSC22D1,KLF9,YBX3,SMAD6,GFI1,ZFP36L2,MSX1,KDM5B,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,ZFPM2,HOXA1,ZIC1,MKX,RERE,EBF1,ZFP62,CEBPB,ID3,NACC2,ZNF214,XBP1,ZNF808,MYRF,PAX9,THAP10,SHOX2,FOXA1,DDIT3,ZNF235 |
| 4.825e-02 | -3.03 | Tetraspanin_CS | interpro domains | IPR018503 | 21 | 5 | 18492 | 1811 |
TSPAN12,CD37,TSPAN9,TSPAN17,CD53 |
| 4.828e-02 | -3.03 | GRIP1 (glutamate receptor interacting protein 1) | protein interactions | 23426 | 48 | 9 | 17029 | 1718 |
GPR37,SMAD3,EFNB2,LATS2,NUMBL,GRIK2,TES,GRIP1,AGAP2 |
| 4.828e-02 | -3.03 | GO_MODULATION_OF_SYNAPTIC_TRANSMISSION | MSigDB lists | GO_MODULATION_OF_SYNAPTIC_TRANSMISSION | 294 | 38 | 17377 | 1707 |
CACNG3,GRIK2,SYT12,OPHN1,CLSTN2,ABAT,SLC1A3,NRXN1,BCAN,KCNC4,PFN2,ABHD6,PPP1R9A,UNC13B,CA2,CNTN4,BCHE,NCAM1,STXBP1,RIMS2,DBN1,RAB3B,RAPGEF2,LRRK2,SHANK2,NLGN4X,SNAP25,BAIAP2,DKK1,GNAI1,SNCA,KCNMB4,PLK2,OXTR,PPARGC1A,SEPT5,LZTS1,MEF2C |
| 4.832e-02 | -3.03 | TSAI_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | TSAI_RESPONSE_TO_IONIZING_RADIATION | 146 | 21 | 17377 | 1707 |
VEGFC,LGALS3,FN1,AKAP5,PTPN6,NFE2L1,CCNG1,BATF,FGFR1,SMAD3,CXCL10,MSC,TGFBR3,MYC,ITGA2,MAP7,BBC3,SGK1,DLX2,ENO1,DDIT3 |
| 4.835e-02 | -3.03 | GO_CONTRACTILE_FIBER | MSigDB lists | GO_CONTRACTILE_FIBER | 206 | 28 | 17377 | 1707 |
PAK1,SCN5A,SYNPO2,ANK2,SCN8A,JPH1,FHL2,RYR2,FERMT2,OBSCN,PALLD,FHOD3,NOS1AP,BAG3,FBXO32,KCNN2,PDLIM3,ALDOA,AHNAK2,ACTA2,SVIL,MYH15,TMOD2,MYOM2,TPM1,ENO1,NEB,ATP2B4 |
| 4.836e-02 | -3.03 | cortical actin cytoskeleton | cellular component | GO:0030864 | 75 | 12 | 18223 | 1724 |
GSN,PLEKHH2,MYADM,WIPF3,CAP2,DSTN,HIP1,PLS1,RTKN2,MYRIP,CDH2,PPP1R9A |
| 4.839e-02 | -3.03 | C2 | smart domains | SM00239 | 122 | 20 | 9493 | 1056 |
PLA2G4A,DOC2A,RASAL2,SYT12,CAPN5,MCTP2,HECW2,RASA3,PRKCA,SYT14,PLCB1,PCLO,RAB11FIP5,CPNE2,UNC13B,PRKCB,PIK3C2B,DAB2IP,TC2N,RIMS2 |
| 4.840e-02 | -3.03 | human chr7p12.1 | chromosome location | human chr7p12.1 | 5 | 2 | 26185 | 1967 |
GRB10,COBL |
| 4.840e-02 | -3.03 | human chr6q16.3 | chromosome location | human chr6q16.3 | 5 | 2 | 26185 | 1967 |
GRIK2,HACE1 |
| 4.843e-02 | -3.03 | GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN | 163 | 23 | 17377 | 1707 |
FADS1,PDLIM7,INPPL1,LPAR2,GAPDH,LGALS3,SEC24D,SLC36A1,HIP1,TNFRSF10C,NPDC1,SEL1L3,PRRG4,NT5DC2,HOMER3,TMCO3,PRKCD,PAM,CLMN,PCOLCE2,PTPRE,CKAP4,CYP1B1 |
| 4.843e-02 | -3.03 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_48H_ACT_CD4_TCELL_UP | 163 | 23 | 17377 | 1707 |
PLA2G4A,SLC40A1,FN1,SLC39A8,MGST3,KIAA1324L,GATA3,HECW2,RHPN2,RNF125,ABAT,IKZF2,ABHD6,DYNC2LI1,MAOA,PTPRN2,COG3,RAB27B,MID1,RAB30,DCBLD1,IGSF3,GAB2 |
| 4.846e-02 | -3.03 | MODULE_19 | MSigDB lists | MODULE_19 | 303 | 39 | 17377 | 1707 |
GNG12,IGFBP6,RHOD,LDLR,COBLL1,ZIC2,ITPR2,DDIT4,MTUS1,EPB41L3,ABLIM1,TGFBR3,MSMO1,BCL6,SGK1,SERPINH1,NCAM1,AGL,CPE,SLIT2,RIMS2,PDGFRB,FADS1,COL6A2,CD55,NR4A1,ACO1,KCND3,RARRES2,HLF,WWTR1,RAB31,HPGD,MAOA,GRB10,ZBTB20,TPM1,CDH2,MEF2C |
| 4.847e-02 | -3.03 | RmlC-like_jellyroll | interpro domains | IPR014710 | 42 | 8 | 18492 | 1811 |
BVES,SLC9C1,RAPGEF2,KCNH5,RAPGEF4,PRKG1,PRKG2,PRKAR2B |
| 4.848e-02 | -3.03 | V$AP1_Q6 | MSigDB lists | V$AP1_Q6 | 241 | 32 | 17377 | 1707 |
PLBD2,NDRG2,STAT5B,ABHD4,PRR7,PHLDA2,COL27A1,MAP1A,SCRN1,ENO1,PDGFRB,GAB2,GAPDH,MARK1,DSTN,DCHS1,FGF12,VIM,ATP1B1,PRDM1,UCHL3,GNAI1,TSKU,MAP2,PKN3,ALDOA,ABI3,DIRAS1,COBL,RAB30,SFN,LPP |
| 4.848e-02 | -3.03 | V$WHN_B | MSigDB lists | V$WHN_B | 241 | 32 | 17377 | 1707 |
BDNF,NUDT10,ANKRD13B,PRSS16,KLHL13,ESRRG,OPHN1,GABRG2,SLITRK5,COL4A5,SNX9,PFN2,FSTL5,PCDH7,GJC1,EBF1,FOXP2,ZNF362,ICA1,CDC14B,TMEM86A,STC2,KCNS3,PPARGC1A,HOXB9,SPRY2,SFN,FOXA1,ZNF385A,POU3F3,BTRC,CRYL1 |
| 4.851e-02 | -3.03 | regulation of cell junction assembly | biological process | GO:1901888 | 82 | 13 | 17256 | 1658 |
EPB41L5,EPHA3,SMAD3,PHLDB2,PTPRJ,RHOD,SLK,RAPGEF2,TJP1,NRP1,NPHP1,OCLN,SNAI2 |
| 4.853e-02 | -3.03 | regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis | biological process | GO:1905310 | 4 | 2 | 17256 | 1658 |
SEMA3C,BMP4 |
| 4.853e-02 | -3.03 | reelin-mediated signaling pathway | biological process | GO:0038026 | 4 | 2 | 17256 | 1658 |
DAB2IP,VLDLR |
| 4.853e-02 | -3.03 | ferrous iron transport | biological process | GO:0015684 | 4 | 2 | 17256 | 1658 |
SLC39A14,SLC40A1 |
| 4.853e-02 | -3.03 | cholesterol biosynthetic process via desmosterol | biological process | GO:0033489 | 4 | 2 | 17256 | 1658 |
DHCR7,DHCR24 |
| 4.853e-02 | -3.03 | regulation of lactation | biological process | GO:1903487 | 4 | 2 | 17256 | 1658 |
CSN2,XBP1 |
| 4.853e-02 | -3.03 | regulation of determination of dorsal identity | biological process | GO:2000015 | 4 | 2 | 17256 | 1658 |
ACVR1,DDIT3 |
| 4.853e-02 | -3.03 | ferrous iron transmembrane transport | biological process | GO:1903874 | 4 | 2 | 17256 | 1658 |
SLC39A14,SLC40A1 |
| 4.853e-02 | -3.03 | immunoglobulin secretion | biological process | GO:0048305 | 4 | 2 | 17256 | 1658 |
POU2F2,TNFSF13B |
| 4.853e-02 | -3.03 | regulation of serine C-palmitoyltransferase activity | biological process | GO:1904220 | 4 | 2 | 17256 | 1658 |
SERINC5,SERINC2 |
| 4.853e-02 | -3.03 | positive regulation of calcium-transporting ATPase activity | biological process | GO:1901896 | 4 | 2 | 17256 | 1658 |
RYR2,HSPA2 |
| 4.853e-02 | -3.03 | transsulfuration | biological process | GO:0019346 | 4 | 2 | 17256 | 1658 |
CBS,CTH |
| 4.853e-02 | -3.03 | renal sodium ion absorption | biological process | GO:0070294 | 4 | 2 | 17256 | 1658 |
SGK1,KLHL3 |
| 4.853e-02 | -3.03 | phytosteroid biosynthetic process | biological process | GO:0016129 | 4 | 2 | 17256 | 1658 |
ERG28,DHCR7 |
| 4.853e-02 | -3.03 | L-arginine transmembrane transport | biological process | GO:1903400 | 4 | 2 | 17256 | 1658 |
SLC7A1,SLC7A2 |
| 4.853e-02 | -3.03 | cell migration involved in endocardial cushion formation | biological process | GO:0003273 | 4 | 2 | 17256 | 1658 |
DCHS1,SNAI2 |
| 4.853e-02 | -3.03 | cholesterol biosynthetic process via lathosterol | biological process | GO:0033490 | 4 | 2 | 17256 | 1658 |
DHCR7,DHCR24 |
| 4.853e-02 | -3.03 | positive regulation of penile erection | biological process | GO:0060406 | 4 | 2 | 17256 | 1658 |
OXTR,P2RY1 |
| 4.853e-02 | -3.03 | positive regulation of high voltage-gated calcium channel activity | biological process | GO:1901843 | 4 | 2 | 17256 | 1658 |
CACNB2,CACNA2D1 |
| 4.853e-02 | -3.03 | secretory granule localization | biological process | GO:0032252 | 4 | 2 | 17256 | 1658 |
RASGRP1,SYBU |
| 4.853e-02 | -3.03 | L-lysine catabolic process | biological process | GO:0019477 | 4 | 2 | 17256 | 1658 |
AADAT,AASS |
| 4.853e-02 | -3.03 | neural crest cell migration involved in autonomic nervous system development | biological process | GO:1901166 | 4 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 4.853e-02 | -3.03 | response to methotrexate | biological process | GO:0031427 | 4 | 2 | 17256 | 1658 |
ABCC2,ASNS |
| 4.853e-02 | -3.03 | myeloid progenitor cell differentiation | biological process | GO:0002318 | 4 | 2 | 17256 | 1658 |
JAM3,MLF1 |
| 4.853e-02 | -3.03 | endothelial cell-cell adhesion | biological process | GO:0071603 | 4 | 2 | 17256 | 1658 |
THBS4,CYP1B1 |
| 4.853e-02 | -3.03 | quinolinate metabolic process | biological process | GO:0046874 | 4 | 2 | 17256 | 1658 |
KMO,QPRT |
| 4.853e-02 | -3.03 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling | biological process | GO:0060665 | 4 | 2 | 17256 | 1658 |
HGF,FGFR1 |
| 4.853e-02 | -3.03 | positive regulation of retinoic acid receptor signaling pathway | biological process | GO:0048386 | 4 | 2 | 17256 | 1658 |
CTBP2,TRIM16 |
| 4.853e-02 | -3.03 | brain-derived neurotrophic factor receptor signaling pathway | biological process | GO:0031547 | 4 | 2 | 17256 | 1658 |
BDNF,RAPGEF2 |
| 4.853e-02 | -3.03 | Wnt signaling pathway involved in somitogenesis | biological process | GO:0090244 | 4 | 2 | 17256 | 1658 |
LRP6,DKK1 |
| 4.853e-02 | -3.03 | protein localization to adherens junction | biological process | GO:0071896 | 4 | 2 | 17256 | 1658 |
DSP,MPP7 |
| 4.853e-02 | -3.03 | folic acid-containing compound catabolic process | biological process | GO:0009397 | 4 | 2 | 17256 | 1658 |
ALDH1L2,ALDH1L1 |
| 4.853e-02 | -3.03 | protein localization to paranode region of axon | biological process | GO:0002175 | 4 | 2 | 17256 | 1658 |
EPB41L3,UGT8 |
| 4.853e-02 | -3.03 | sympathetic neuron projection guidance | biological process | GO:0097491 | 4 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 4.853e-02 | -3.03 | L-lysine catabolic process to acetyl-CoA | biological process | GO:0019474 | 4 | 2 | 17256 | 1658 |
AADAT,AASS |
| 4.853e-02 | -3.03 | L-lysine metabolic process | biological process | GO:0046440 | 4 | 2 | 17256 | 1658 |
AADAT,AASS |
| 4.853e-02 | -3.03 | desmosome assembly | biological process | GO:0002159 | 4 | 2 | 17256 | 1658 |
PKP2,PRKCA |
| 4.853e-02 | -3.03 | branched-chain amino acid transport | biological process | GO:0015803 | 4 | 2 | 17256 | 1658 |
SLC6A15,SLC3A2 |
| 4.853e-02 | -3.03 | positive regulation of odontogenesis of dentin-containing tooth | biological process | GO:0042488 | 4 | 2 | 17256 | 1658 |
ENAM,CSF1 |
| 4.853e-02 | -3.03 | peptidyl-lysine oxidation | biological process | GO:0018057 | 4 | 2 | 17256 | 1658 |
LOXL4,NUGGC |
| 4.853e-02 | -3.03 | response to odorant | biological process | GO:1990834 | 4 | 2 | 17256 | 1658 |
FGF13,CTSV |
| 4.853e-02 | -3.03 | negative regulation of monocyte chemotaxis | biological process | GO:0090027 | 4 | 2 | 17256 | 1658 |
NBL1,SLIT2 |
| 4.853e-02 | -3.03 | lipid tube assembly | biological process | GO:0060988 | 4 | 2 | 17256 | 1658 |
SH3GL2,SNX9 |
| 4.853e-02 | -3.03 | sympathetic neuron projection extension | biological process | GO:0097490 | 4 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 4.853e-02 | -3.03 | retinal blood vessel morphogenesis | biological process | GO:0061304 | 4 | 2 | 17256 | 1658 |
FZD4,CYP1B1 |
| 4.853e-02 | -3.03 | sequestering of BMP in extracellular matrix | biological process | GO:0035582 | 4 | 2 | 17256 | 1658 |
NBL1,FBN1 |
| 4.853e-02 | -3.03 | anterograde dendritic transport of neurotransmitter receptor complex | biological process | GO:0098971 | 4 | 2 | 17256 | 1658 |
KIF5C,KIF5A |
| 4.853e-02 | -3.03 | regulation of negative chemotaxis | biological process | GO:0050923 | 4 | 2 | 17256 | 1658 |
ROBO2,SLIT2 |
| 4.853e-02 | -3.03 | regulation of G-protein coupled receptor internalization | biological process | GO:1904020 | 4 | 2 | 17256 | 1658 |
NECAB2,APELA |
| 4.853e-02 | -3.03 | regulation of lymphangiogenesis | biological process | GO:1901490 | 4 | 2 | 17256 | 1658 |
VEGFC,CCBE1 |
| 4.853e-02 | -3.03 | trigeminal ganglion development | biological process | GO:0061551 | 4 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 4.853e-02 | -3.03 | response to iron(II) ion | biological process | GO:0010040 | 4 | 2 | 17256 | 1658 |
SNCA,ACO1 |
| 4.853e-02 | -3.03 | pteridine-containing compound catabolic process | biological process | GO:0042560 | 4 | 2 | 17256 | 1658 |
ALDH1L2,ALDH1L1 |
| 4.853e-02 | -3.03 | intestinal epithelial structure maintenance | biological process | GO:0060729 | 4 | 2 | 17256 | 1658 |
INAVA,TLR4 |
| 4.853e-02 | -3.03 | inosine metabolic process | biological process | GO:0046102 | 4 | 2 | 17256 | 1658 |
ADAL,PNP |
| 4.853e-02 | -3.03 | cellular response to nitrosative stress | biological process | GO:0071500 | 4 | 2 | 17256 | 1658 |
ATG5,DDIT3 |
| 4.853e-02 | -3.03 | osteoblast fate commitment | biological process | GO:0002051 | 4 | 2 | 17256 | 1658 |
SH3PXD2B,RUNX2 |
| 4.853e-02 | -3.03 | planar cell polarity pathway involved in axis elongation | biological process | GO:0003402 | 4 | 2 | 17256 | 1658 |
WNT11,MAGI2 |
| 4.853e-02 | -3.03 | positive regulation of oxidative stress-induced neuron death | biological process | GO:1903223 | 4 | 2 | 17256 | 1658 |
TLR4,TLR6 |
| 4.853e-02 | -3.03 | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator | biological process | GO:1902255 | 4 | 2 | 17256 | 1658 |
RPL26,MSX1 |
| 4.853e-02 | -3.03 | toxin biosynthetic process | biological process | GO:0009403 | 4 | 2 | 17256 | 1658 |
CBS,CTH |
| 4.853e-02 | -3.03 | cloaca development | biological process | GO:0035844 | 4 | 2 | 17256 | 1658 |
WNT11,BMP4 |
| 4.853e-02 | -3.03 | homoserine metabolic process | biological process | GO:0009092 | 4 | 2 | 17256 | 1658 |
CBS,CTH |
| 4.853e-02 | -3.03 | epithelial cell proliferation involved in renal tubule morphogenesis | biological process | GO:2001013 | 4 | 2 | 17256 | 1658 |
LGR4,MEF2C |
| 4.853e-02 | -3.03 | phytosteroid metabolic process | biological process | GO:0016128 | 4 | 2 | 17256 | 1658 |
ERG28,DHCR7 |
| 4.853e-02 | -3.03 | myo-inositol transport | biological process | GO:0015798 | 4 | 2 | 17256 | 1658 |
SLC2A13,PGAP1 |
| 4.853e-02 | -3.03 | nerve growth factor processing | biological process | GO:0032455 | 4 | 2 | 17256 | 1658 |
PCSK6,PCSK5 |
| 4.853e-02 | -3.03 | hypothalamus cell migration | biological process | GO:0021855 | 4 | 2 | 17256 | 1658 |
NRP1,SEMA3A |
| 4.853e-02 | -3.03 | platelet activating factor biosynthetic process | biological process | GO:0006663 | 4 | 2 | 17256 | 1658 |
PLA2G4A,LPCAT2 |
| 4.855e-02 | -3.03 | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | MSigDB lists | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP | 384 | 48 | 17377 | 1707 |
EXPH5,LRFN5,MRC2,DUSP8,REL,SYT12,PLEKHA5,KIF5A,OLAH,BIK,PKP2,NTRK3,SEZ6L2,DDR1,HPCAL4,PHLDA2,ARHGAP44,RAB11FIP5,SYCP2,ZNF362,AKAP7,ACTA2,EPHB6,POU2F2,ARL4D,NIPAL2,MAST4,ETV1,ULBP1,DUSP1,NR4A1,CAPN5,EFHC2,SHANK2,DUSP9,CHRNA6,DSP,DCBLD2,SNCA,MSC,MPP2,PTPRS,GRB10,MAPK10,RNF122,PTGES,FOXA1,DDIT3 |
| 4.859e-02 | -3.02 | GO_REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_MAP_KINASE_ACTIVITY | 312 | 40 | 17377 | 1707 |
TNIK,NEK10,AVPI1,DUSP8,FZD8,NTRK3,PKN1,TPD52L1,IGF1R,PRKCD,GHR,DAB2IP,IQGAP3,TLR4,TNFRSF11A,SPRY2,SYK,RASGRP1,PDGFRB,DUSP1,HMGCR,PAK1,FZD4,PTPN6,TGFA,LRRK2,DUSP9,CD40,TLR6,FGFR1,MAPKAPK2,TRIB3,PTPRJ,MAP2K6,ERN1,DUSP19,DIRAS1,HGF,BMP4,MAPK10 |
| 4.865e-02 | -3.02 | GO_SINGLE_ORGANISM_BEHAVIOR | MSigDB lists | GO_SINGLE_ORGANISM_BEHAVIOR | 375 | 47 | 17377 | 1707 |
PDE1B,FGF13,GRIK2,ATP8A1,EPS8,GABRG2,BTBD9,ABAT,SLC1A3,NRXN1,CACNB4,FOXP2,RNF180,KCNAB1,CHRNA5,BCHE,AFF2,SGK1,ETV1,ZNF385A,HMGCR,USP2,MEIS2,LRRK2,VLDLR,SHANK2,FGF12,ADCY1,SLITRK5,NLGN4X,PRKAR2B,SNAP25,SDK1,PLCB1,HOXA1,ZIC1,DKK1,SNCA,CEBPB,PLK2,THBS4,GRIN2D,TMOD2,OXTR,NPHP1,ATP1A3,MEF2C |
| 4.866e-02 | -3.02 | SRM (spermidine synthase) | protein interactions | 6723 | 27 | 6 | 17029 | 1718 |
DUSP9,EFHC1,FN1,HK2,DUSP19,DUSP1 |
| 4.866e-02 | -3.02 | ABCB8 (ATP binding cassette subfamily B member 8) | protein interactions | 11194 | 27 | 6 | 17029 | 1718 |
GPR37,RAB11FIP5,SLC2A12,SLC1A5,NCR3LG1,RASGRP1 |
| 4.866e-02 | -3.02 | RABGGTA (Rab geranylgeranyltransferase subunit alpha) | protein interactions | 5875 | 27 | 6 | 17029 | 1718 |
GAPDH,BMPR2,RAB6B,RAB30,LAMP3,RAB31 |
| 4.869e-02 | -3.02 | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_180MIN_UP | 121 | 18 | 17377 | 1707 |
ENAM,MYO1D,ANTXR2,KLF8,PLBD2,ACVR1,ENO2,ABHD13,NIPSNAP3B,GAS1,TBC1D19,SLC39A14,SLC7A11,WFS1,MATN2,RTKN2,KLHL31,SEMA3A |
| 4.874e-02 | -3.02 | cellular potassium ion transport | biological process | GO:0071804 | 158 | 22 | 17256 | 1658 |
KCNV1,KCNIP3,KCNQ3,SLC9C1,KCNH5,KCND3,ATP1B1,SLC1A3,SLC12A6,KCNC4,SLC9A7,KCNJ4,LRRC55,KCNK15,KCNMB4,KCNAB1,KCNN2,KCNG1,KCNMB3,KCNS3,KCNB2,ATP1A3 |
| 4.874e-02 | -3.02 | potassium ion transmembrane transport | biological process | GO:0071805 | 158 | 22 | 17256 | 1658 |
KCNV1,KCNIP3,KCNQ3,SLC9C1,KCNH5,KCND3,ATP1B1,SLC1A3,SLC12A6,KCNC4,SLC9A7,KCNJ4,LRRC55,KCNK15,KCNMB4,KCNAB1,KCNN2,KCNG1,KCNMB3,KCNS3,KCNB2,ATP1A3 |
| 4.878e-02 | -3.02 | BIOCARTA_NOS1_PATHWAY | MSigDB lists | BIOCARTA_NOS1_PATHWAY | 21 | 5 | 17377 | 1707 |
GRIN2D,PRKAR2B,PRKCA,PRKCB,PRKACB |
| 4.878e-02 | -3.02 | GO_NEGATIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PEPTIDYL_SERINE_PHOSPHORYLATION | 21 | 5 | 17377 | 1707 |
HGF,PDE4D,CNKSR3,DDIT4,DKK1 |
| 4.878e-02 | -3.02 | WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC | MSigDB lists | WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC | 21 | 5 | 17377 | 1707 |
CLSTN2,TRIB3,ATF3,DDIT3,IGFBP3 |
| 4.878e-02 | -3.02 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | MSigDB lists | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | 21 | 5 | 17377 | 1707 |
SCN5A,SCN2A,KCNQ3,SCN1B,SCN8A |
| 4.878e-02 | -3.02 | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | 21 | 5 | 17377 | 1707 |
CEBPA,FGR,ALOX5AP,GYPC,PTPN6 |
| 4.878e-02 | -3.02 | GO_WNT_ACTIVATED_RECEPTOR_ACTIVITY | MSigDB lists | GO_WNT_ACTIVATED_RECEPTOR_ACTIVITY | 21 | 5 | 17377 | 1707 |
LRP6,TSPAN12,FZD4,FZD8,FZD1 |
| 4.878e-02 | -3.02 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_SUSTAINED_IN_MONOCYTE_UP | 21 | 5 | 17377 | 1707 |
CSF1,PPFIBP1,EPS8,QPRT,HOMER3 |
| 4.878e-02 | -3.02 | LANDIS_ERBB2_BREAST_TUMORS_65_UP | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_65_UP | 21 | 5 | 17377 | 1707 |
ITPR2,TPD52L1,DSG2,PERP,FHDC1 |
| 4.878e-02 | -3.02 | chr3q23 | MSigDB lists | chr3q23 | 21 | 5 | 17377 | 1707 |
CLSTN2,PLS1,NMNAT3,ZBTB38,WWTR1 |
| 4.878e-02 | -3.02 | GO_NLS_BEARING_PROTEIN_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_NLS_BEARING_PROTEIN_IMPORT_INTO_NUCLEUS | 21 | 5 | 17377 | 1707 |
RANBP2,KPNA3,IPO5,RERE,TRPS1 |
| 4.878e-02 | -3.02 | chr2q23 | MSigDB lists | chr2q23 | 21 | 5 | 17377 | 1707 |
KIF5C,ACVR1,SCN2A,RND3,FMNL2 |
| 4.878e-02 | -3.02 | chr14q31 | MSigDB lists | chr14q31 | 21 | 5 | 17377 | 1707 |
EML5,STON2,GPR65,PTPN21,SPATA7 |
| 4.879e-02 | -3.02 | GO_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_ACTIVE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 339 | 43 | 17377 | 1707 |
SLC6A9,ATP8A1,ATP6V1E2,SLC36A4,SLC1A3,SLC7A2,SLC2A13,SLC12A6,SLCO3A1,SLC9A7,MCU,SLC7A11,ABCA5,SLC22A18,SLC16A2,SLC10A7,SLC2A12,SLC6A15,SLC16A9,SLCO4C1,ATP6AP1L,SLC45A3,ATP2B1,SLC3A2,SLC37A1,ABCC4,SLC36A1,ABCC2,ATP1B1,SLC7A1,TMCO3,ATP7B,MFSD2A,SLC2A6,SLC7A5,CDH17,SLCO5A1,SLC1A5,SLC9B1,SLC16A10,ATP2B4,ATP1A3,ABCG1 |
| 4.880e-02 | -3.02 | clathrin-coated pit | cellular component | GO:0005905 | 67 | 11 | 18223 | 1724 |
TNK2,FCHO2,LDLR,VLDLR,SH3BP4,HIP1,INPP5F,CTTN,MYO6,LRP3,LRP12 |
| 4.894e-02 | -3.02 | V$AP1_Q2 | MSigDB lists | V$AP1_Q2 | 250 | 33 | 17377 | 1707 |
FARP1,PLBD2,ID1,IGFBP6,ASS1,STAT5B,COL27A1,ZNF362,MAP1A,SCRN1,PDGFRB,GAB2,GAPDH,USP2,MEIS2,DSTN,PRDM13,DCHS1,FGF12,VIM,PRDM1,ARRDC4,UCHL3,BAIAP2,GPR150,GNAI1,ZIC1,GSN,MAP2,PKN3,PAX9,SFN,LPP |
| 4.894e-02 | -3.02 | V$POU3F2_02 | MSigDB lists | V$POU3F2_02 | 250 | 33 | 17377 | 1707 |
ENAM,LRFN5,NEK10,BMPR2,CHCHD7,PLAG1,OGDHL,GABRG2,CADM2,ATOH1,SATB1,HPCAL4,TBC1D19,NEO1,MTUS1,FOXP2,ZNF827,IFT81,SLC22A17,COL25A1,LHX6,SAMD11,SCRN1,SLC6A15,PPP2R2B,SCN2A,ERRFI1,HOXB9,SEMA3A,NEUROG2,MYT1,HS6ST3,MEF2C |
| 4.894e-02 | -3.02 | secretion by cell | biological process | GO:0032940 | 983 | 110 | 17256 | 1658 |
DOC2A,FRMPD3,SCAMP1,PRSS12,SYT12,ATP8A1,DNAJC3,VAMP8,LILRB1,GATA3,CANX,SYT14,NRXN1,LCP2,PCLO,DOCK2,CBLN1,PCDH7,TXNDC5,SCIN,CD53,UNC13B,PPFIA2,ALDOC,ITGB3,RAB26,LIN7A,SCRN1,STEAP3,PROS1,POU2F2,ARL4D,SYNGR3,RAB27B,TLR4,IL1RAP,RASGRP1,GCA,CD55,ABCC4,FZD4,WLS,PTPN6,EXOC6B,LRMP,ACVR2B,RARRES2,COTL1,DSP,FRK,TRIM9,GSN,PTPRJ,HPSE,NCKAP1L,ALDOA,HGF,SEPT5,TC2N,PCSK5,TYRO3,SLC6A9,FN1,LGALS3,STXBP5L,STXBP6,TNFSF13B,SELL,GAS6,SLC1A3,APBA1,SELENOP,ARHGAP44,RAB11FIP5,MCOLN2,EEF2,PRKCD,CADPS2,SLCO4C1,AGL,STXBP1,SYK,CKAP4,RIMS2,PCSK6,PAK1,VEGFC,QSOX1,RAB3B,PNP,SLC27A2,RAPGEF4,PPFIA4,PHACTR2,NPC2,SNAP25,ATP11A,TLR6,ILDR2,PTPRC,FGR,PRCP,RAB31,SELENOM,PTPRN2,PLD1,SLC1A5,MME,SNPH,STOM |
| 4.896e-02 | -3.02 | thyroid-carcinoma-medullary_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-medullary_carcinoma | 296 | 38 | 17385 | 1698 |
FRMPD3,MXI1,CELSR1,PLXNA2,PKP2,NPM1,NTRK3,P2RY1,DOCK3,USP30,TNKS1BP1,RBM11,SEMA6A,HPS1,GTSF1,PRKG1,MYH15,MET,TSHR,SP140L,PARD3B,ADCY1,PRICKLE1,PHACTR2,FGFR1,BATF3,NRG3,PTPRJ,TERT,FBN1,GBP1,INPP4B,DISP2,PPARGC1A,TTC39A,TRPC3,SPOCK3,DOCK9 |
| 4.896e-02 | -3.02 | medullary_carcinoma | COSMIC cancer mutations | medullary_carcinoma | 296 | 38 | 17385 | 1698 |
FRMPD3,MXI1,CELSR1,PLXNA2,PKP2,NPM1,NTRK3,P2RY1,DOCK3,USP30,TNKS1BP1,RBM11,SEMA6A,HPS1,GTSF1,PRKG1,MYH15,MET,TSHR,SP140L,PARD3B,ADCY1,PRICKLE1,PHACTR2,FGFR1,BATF3,NRG3,PTPRJ,TERT,FBN1,GBP1,INPP4B,DISP2,PPARGC1A,TTC39A,TRPC3,SPOCK3,DOCK9 |
| 4.900e-02 | -3.02 | cell migration in hindbrain | biological process | GO:0021535 | 15 | 4 | 17256 | 1658 |
RBFOX2,CTNNA2,RERE,PLXNA2 |
| 4.900e-02 | -3.02 | fructose metabolic process | biological process | GO:0006000 | 15 | 4 | 17256 | 1658 |
PFKFB4,PFKFB2,ALDOC,ALDOA |
| 4.900e-02 | -3.02 | anatomical structure arrangement | biological process | GO:0048532 | 15 | 4 | 17256 | 1658 |
BMPR1A,NRP1,SEMA3A,TFAP2A |
| 4.900e-02 | -3.02 | coenzyme catabolic process | biological process | GO:0009109 | 15 | 4 | 17256 | 1658 |
NUDT12,ALDH1L2,ALDH1L1,NUDT17 |
| 4.900e-02 | -3.02 | positive regulation of neurotransmitter secretion | biological process | GO:0001956 | 15 | 4 | 17256 | 1658 |
UNC13B,KMO,STXBP1,SNCA |
| 4.900e-02 | -3.02 | mechanosensory behavior | biological process | GO:0007638 | 15 | 4 | 17256 | 1658 |
FOXP2,SLC1A3,NRXN1,ETV1 |
| 4.900e-02 | -3.02 | oxygen transport | biological process | GO:0015671 | 15 | 4 | 17256 | 1658 |
HBE1,HBG2,IPCEF1,MYC |
| 4.915e-02 | -3.01 | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | 189 | 26 | 17377 | 1707 |
LATS2,ITGB7,ANTXR2,B3GALT1,LGALS3,CSN2,GJB2,MVD,LDLR,BNIP3L,RASA3,KCTD12,RASD1,DDR1,GJC1,HOMER3,IDI1,MSMO1,SQLE,IQGAP3,PPARGC1A,CPE,SNX10,NEUROG2,LIFR,GATM |
| 4.915e-02 | -3.01 | GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN | MSigDB lists | GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN | 189 | 26 | 17377 | 1707 |
RIN2,GCNT2,PNP,ITPRIP,FBXO4,GPR65,SPATA13,ASS1,RASA3,PDE8A,ISG20,CXCL10,RSL24D1,OTUD1,TRIM34,CHRNA5,GNB4,RAP2A,SLC2A6,PLEKHG1,CAB39L,ST8SIA1,IQSEC2,TNFRSF11A,SPRY2,ABCG1 |
| 4.915e-02 | -3.01 | GSE24726_WT_VS_E2-2_KO_PDC_DN | MSigDB lists | GSE24726_WT_VS_E2-2_KO_PDC_DN | 189 | 26 | 17377 | 1707 |
PLEKHA8,DOCK1,UBASH3B,DNAJC3,ATOX1,LITAF,FASN,IL13RA1,DNER,CLN5,AARS,CEBPB,ATXN7L1,GBGT1,AKAP7,P4HA2,PRKCD,PRELID2,EMILIN2,SQLE,CNNM2,LMAN2,MET,TANC2,CEBPD,PARP9 |
| 4.915e-02 | -3.01 | GSE3982_DC_VS_BASOPHIL_DN | MSigDB lists | GSE3982_DC_VS_BASOPHIL_DN | 189 | 26 | 17377 | 1707 |
MEIS2,RNF144A,KIF5A,BEGAIN,KIF21B,DENND3,KBTBD11,IL18R1,RPL34,ISG20,GALNT3,SFXN1,CHN1,ABLIM1,ZNF266,BACH2,DNAH6,PMAIP1,EIF1,ERCC5,PDE4D,MYRIP,SMYD3,DDIT3,IGFBP3,TPT1 |
| 4.915e-02 | -3.01 | GSE17721_CTRL_VS_CPG_2H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_2H_BMDC_DN | 189 | 26 | 17377 | 1707 |
ANO10,FER,UGT8,RAB3B,SLC27A2,GRID1,PRICKLE1,LHPP,CD40,TTC28,DYNC1I1,KREMEN1,FKBP11,F3,IFT81,KMO,ITGB3,KLF5,DLG2,PIP5KL1,PTPRE,SNX10,NTNG1,PTGES,HS6ST3,CES3 |
| 4.915e-02 | -3.01 | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN | 189 | 26 | 17377 | 1707 |
CREB3L2,CD55,ALDH2,ALOX5AP,SIDT1,RNF144A,STAT4,LITAF,KCTD12,NPC2,FNDC3A,SEL1L3,HERPUD1,MAPKAPK2,IGF1R,DACT1,PRKCD,SLC7A5,OPN3,HK2,SH3BP4,TSPAN13,RNF130,TNFRSF17,DHCR7,MEF2C |
| 4.915e-02 | -3.01 | GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DN | 189 | 26 | 17377 | 1707 |
DBN1,CFH,BMPR2,PNRC1,EPS8,ATOX1,CYP4V2,VIM,SDK1,C3orf70,DOCK2,PLEKHB1,HERPUD1,HTR7,RNF180,PPM1E,RNF150,MYADM,TMEM86A,SCRN1,CLMN,SVIL,DIRAS1,SCN2A,SYNGR3,PTPRE |
| 4.915e-02 | -3.01 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | 189 | 26 | 17377 | 1707 |
EML5,MYCBP2,PDK1,RAB6B,ITGA6,RIMKLA,ST6GALNAC3,ADAMTS6,TMEM170B,INPP1,HERPUD1,HOPX,AHRR,SETDB2,SOAT2,MSMO1,ABI3,RUNDC3B,SQLE,IPCEF1,SLC1A5,GFI1,PTPRE,CYP1B1,NOS3,IGFBP3 |
| 4.915e-02 | -3.01 | GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | 189 | 26 | 17377 | 1707 |
EPHA3,PTCH2,PLA2G4A,EML5,FER,IGFBP6,CD276,FHDC1,WWC1,DYNC1I1,SNCA,IRS2,INHBC,TCF7L1,ZNF354A,PLK2,AFF2,MATN2,SMTN,ZNF808,TSPAN13,PPARGC1A,GFI1,TSHR,IL9R,CTNND2 |
| 4.915e-02 | -3.01 | GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 189 | 26 | 17377 | 1707 |
QSOX1,CARD6,NR4A1,GPR65,GALNT6,ST6GAL1,SELL,RASA3,COTL1,GRK6,CD7,INPP1,STK24,SLC39A14,SEMA4F,PCBP4,EHD3,ITGB3,HS3ST3B1,PACSIN1,RCAN3,CMPK2,MYO6,SLFN5,TSPAN9,TESC |
| 4.915e-02 | -3.01 | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN | MSigDB lists | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN | 189 | 26 | 17377 | 1707 |
CHSY3,FN1,BIK,PRDM1,FAM198B,GAS6,C3orf70,NHP2,UBTD2,NCS1,FGFR1,MCOLN2,ATPAF2,AK1,BAG3,OR2T33,PIK3AP1,GNB4,SQLE,TMED9,HS3ST3B1,MET,RRAS2,RASGRP1,NUDT17,SNX7 |
| 4.916e-02 | -3.01 | Viral mRNA Translation | REACTOME pathways | R-HSA-192823 | 92 | 14 | 10287 | 971 |
RPS20,RPL26,RPL12,RPL28,RPS11,DNAJC3,RPL21,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPL34,RPS13 |
| 4.916e-02 | -3.01 | Peptide chain elongation | REACTOME pathways | R-HSA-156902 | 92 | 14 | 10287 | 971 |
RPS20,RPL26,RPL12,EEF2,RPL28,RPS11,RPL21,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPL34,RPS13 |
| 4.920e-02 | -3.01 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP | 42 | 8 | 17377 | 1707 |
EPB41L3,PNP,FN1,FBN1,GDPD1,EDEM3,FAR2,UNC5B |
| 4.920e-02 | -3.01 | GO_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_STEM_CELL_DIFFERENTIATION | 42 | 8 | 17377 | 1707 |
YAP1,PRICKLE1,DAB2IP,OVOL2,MSTN,ZFP36L2,FOXA1,NKX2-1 |
| 4.920e-02 | -3.01 | PID_THROMBIN_PAR1_PATHWAY | MSigDB lists | PID_THROMBIN_PAR1_PATHWAY | 42 | 8 | 17377 | 1707 |
PRKCB,GNAO1,PRKCD,PRKCA,PKN1,PLCB1,NOS3,GNAI1 |
| 4.920e-02 | -3.01 | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN | MSigDB lists | CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN | 42 | 8 | 17377 | 1707 |
PFKFB2,CACNB2,B3GALT2,PDE4D,MARCKS,NRP1,JAM2,ATP1A3 |
| 4.920e-02 | -3.01 | ROVERSI_GLIOMA_LOH_REGIONS | MSigDB lists | ROVERSI_GLIOMA_LOH_REGIONS | 42 | 8 | 17377 | 1707 |
FERMT2,ARAP2,CNTN4,LRRN1,ADAMTS3,TBC1D1,HEBP1,PPFIBP1 |
| 4.920e-02 | -3.01 | KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION | MSigDB lists | KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION | 42 | 8 | 17377 | 1707 |
IRS2,SGK1,ATP1B1,PRKCA,PRKCB,NR3C2,SFN,ATP1A3 |
| 4.920e-02 | -3.01 | GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | MSigDB lists | GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | 42 | 8 | 17377 | 1707 |
BBC3,BNIP3,HRK,HGF,PMAIP1,FAM162A,BIK,PRELID1 |
| 4.920e-02 | -3.01 | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS | 42 | 8 | 17377 | 1707 |
IRS2,ST6GAL1,BCL6,LILRB1,PRKCQ,BMP4,GAS6,DOCK8 |
| 4.920e-02 | -3.01 | ASTON_MAJOR_DEPRESSIVE_DISORDER_UP | MSigDB lists | ASTON_MAJOR_DEPRESSIVE_DISORDER_UP | 42 | 8 | 17377 | 1707 |
DLGAP1,MN1,PLAGL1,TBC1D1,XYLT1,GSTM3,RRAS2,BCL11A |
| 4.927e-02 | -3.01 | GO_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_CORTICOSTEROID_STIMULUS | 57 | 10 | 17377 | 1707 |
FBXO32,ACVR1,MSTN,SGK1,ASS1,KLF9,ERRFI1,SMYD3,ATP2B1,HEY1 |
| 4.927e-02 | -3.01 | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | MSigDB lists | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 57 | 10 | 17377 | 1707 |
ENPP1,MSTN,PRKCB,PRKCD,PRKCQ,GRB10,RARRES2,MARCKS,PTPRE,GPLD1 |
| 4.929e-02 | -3.01 | FLNC (filamin C) | protein interactions | 2318 | 102 | 16 | 17029 | 1718 |
PHLDB2,SYNPO2,INPPL1,FN1,TES,RAPGEF2,NUAK2,NPM1,CTTNBP2NL,ATOH1,PRKCA,OTUD1,RPS6KA2,ENO1,NPHP1,RAPGEF5 |
| 4.929e-02 | -3.01 | NF1 (neurofibromin 1) | protein interactions | 4763 | 102 | 16 | 17029 | 1718 |
EFNB2,CGN,PHLDB2,RASAL2,PTPN13,TNFSF13B,CBY1,LPIN3,FAM110B,NAV1,RALGPS2,MAP3K21,GRIN2D,TANC2,OSBPL6,GAB2 |
| 4.933e-02 | -3.01 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 259 | 34 | 17377 | 1707 |
RPS20,TSPAN15,PKP2,GAS6,TSPAN17,RPL13A,RPL34,PMAIP1,RPS11,CACNB2,EHD3,REEP1,RAB26,PRKG2,PACSIN1,RPL26L1,RPS23,KCNB2,RPS13,RPL26,ANK2,TRAM1L1,RPL21,ATP1B1,RPL12,MYADM,RPL28,RAB31,TNFRSF1A,BBC3,RPS12,RPL4,CDH2,TESC |
| 4.939e-02 | -3.01 | positive regulation of endothelial cell proliferation | biological process | GO:0001938 | 107 | 16 | 17256 | 1658 |
VEGFC,BMPR2,NR4A1,PRKCA,BMP6,FGFR1,F3,GATA2,APELA,AKT3,THBS4,ITGB3,EGFL7,BMP4,NRP1,VASH2 |
| 4.948e-02 | -3.01 | purine ribonucleoside binding | molecular function | GO:0032550 | 369 | 46 | 17224 | 1680 |
MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,RAP2A,RASD2,EHD3,RAB26,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD |
| 4.950e-02 | -3.01 | RGS | pfam domains | PF00615 | 35 | 7 | 17054 | 1666 |
RGS16,RGS17,GRK6,RGS7,GRK3,RGS10,RGS20 |
| 4.954e-02 | -3.01 | stress-activated protein kinase signaling cascade | biological process | GO:0031098 | 141 | 20 | 17256 | 1658 |
PAK1,TNIK,PAK5,SLK,DUSP9,STRADB,CHUK,PKN1,TNFRSF19,STK24,MAPKAPK2,MAP2K6,ERN1,MAP3K21,MAPK13,DAB2IP,MAPK10,MAP3K20,SYK,BTRC |
| 4.958e-02 | -3.00 | ADAM33 (ADAM metallopeptidase domain 33) | protein interactions | 80332 | 41 | 8 | 17029 | 1718 |
LRP6,EGFL7,TMEM67,AMIGO1,SEMA4F,GALNT12,ZDHHC6,LRP12 |
| 4.958e-02 | -3.00 | NCAM1 (neural cell adhesion molecule 1) | protein interactions | 4684 | 41 | 8 | 17029 | 1718 |
BDNF,SLC30A4,PRKCB,REEP1,NCAM1,GFRA1,FGFR1,ISG20 |
| 4.962e-02 | -3.00 | GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_LY6C_LOW_CXCR5NEG_CD4_EFF_TCELL_D6_LCMV_UP | 138 | 20 | 17377 | 1707 |
JDP2,LRRK2,CAPN5,RHPN2,BCL6B,ATF3,PRKCQ,IL18R1,COL27A1,IL17D,ABCA5,MGAT1,BCHE,EIF4EBP1,NDUFB8,TFAP2A,INPP4B,SLC2A12,GRIN2D,ZNF488 |
| 4.962e-02 | -3.00 | BMI1_DN.V1_UP | MSigDB lists | BMI1_DN.V1_UP | 138 | 20 | 17377 | 1707 |
VEGFC,VLDLR,PLXNA2,KCNC4,ASPH,FGFR1,F3,DKK1,MMP15,PMEPA1,CSF1,STC2,SLC2A6,SLC7A5,INHBE,MARCH3,ACTA2,BMP4,SLC1A5,FES |
| 4.963e-02 | -3.00 | GSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN | MSigDB lists | GSE38697_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN | 113 | 17 | 17377 | 1707 |
ARID5B,FHDC1,CLSTN2,GALNT14,SEL1L3,NEGR1,CHRNA5,RPS6KL1,DLX6,LRRIQ3,REEP1,TIGD4,SLC16A9,LOXL4,PRR16,HOXB9,NR3C2 |
| 4.963e-02 | -3.00 | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | MSigDB lists | WANG_ESOPHAGUS_CANCER_VS_NORMAL_UP | 113 | 17 | 17377 | 1707 |
FN1,NR4A1,C4A,GSTO1,ATF3,PLS1,C1R,SFXN3,MECOM,GALNT3,MYADM,GPRC5B,PMEPA1,EIF1,SMTN,COL9A2,IGFBP3 |
| 4.964e-02 | -3.00 | GO_ANION_TRANSPORT | MSigDB lists | GO_ANION_TRANSPORT | 485 | 59 | 17377 | 1707 |
PLA2G4A,PRKAA2,ANO10,SERINC5,ACSL1,SLC6A9,ATP9A,GABRB2,ATP8A1,LDLR,GABRG2,SLC36A4,GABRR2,SLC1A3,SLC7A2,SLC12A6,APBA1,CACNB4,SLCO3A1,SLC19A2,UNC13B,CA2,SLC22A17,SLC7A11,SLC16A2,PPFIA2,PRELID2,FABP6,PRELID1,SERINC2,SLC6A15,SLC16A9,SLCO4C1,STXBP1,SLC3A2,ABCC4,SLC37A1,SLC27A2,LRRC8B,SLC36A1,CYB5R2,TTYH2,ABCC2,ATP11A,SNAP25,NPC2,ATP10D,CA13,SLC7A1,ENPP1,MFSD2A,OSBPL5,SLC7A5,SH3BP4,SLCO5A1,SLC1A5,SLC16A10,SLC43A1,ABCG1 |
| 4.966e-02 | -3.00 | Signalling by NGF | REACTOME pathways | R-HSA-166520 | 477 | 56 | 10287 | 971 |
BTC,DNM3,PDE1B,FN1,RASAL2,DUSP8,ARHGEF11,CHUK,ITPR2,PRKCA,TIAM2,ARHGEF10L,RPS6KA2,PIK3AP1,MCF2L,PRKCD,ITGB3,ADCY6,DAB2IP,NCAM1,MET,GFRA1,RASGRP1,PRKACB,PDGFRB,PCSK6,DUSP1,FGFR4,IL17RD,VAV3,NR4A1,RAPGEF2,PREX1,ADCY1,DUSP9,RASA3,OBSCN,AGO4,PRKAR2B,FGF17,FGFR1,ARHGEF26,MAPKAPK2,IRS2,TRIB3,NRG3,SH3GL2,BEX3,AKT3,RASGRF2,GRIN2D,MAPK13,HGF,SPRED3,MEF2C,PCSK5 |
| 4.968e-02 | -3.00 | L-serine transmembrane transporter activity | molecular function | GO:0015194 | 9 | 3 | 17224 | 1680 |
SERINC5,SLC1A5,SERINC2 |
| 4.968e-02 | -3.00 | serine transmembrane transporter activity | molecular function | GO:0022889 | 9 | 3 | 17224 | 1680 |
SERINC5,SLC1A5,SERINC2 |
| 4.968e-02 | -3.00 | cyclic nucleotide-dependent protein kinase activity | molecular function | GO:0004690 | 9 | 3 | 17224 | 1680 |
PRKG2,PRKACB,PRKG1 |
| 4.970e-02 | -3.00 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_16H_TSST_ACT_DN | 172 | 24 | 17377 | 1707 |
CD55,CSN2,AASS,BNIP3L,FHL2,MAFB,SYNJ2BP,CCNG1,SNAP25,FAM13A,KBTBD11,RGS17,NELL2,WDR19,NXPH4,TOX,FHIT,LRRK1,SP140,NKX2-8,NR3C2,FKBP14,SP140L,NOS3 |
| 4.973e-02 | -3.00 | regulation of immune effector process | biological process | GO:0002697 | 347 | 43 | 17256 | 1658 |
LGALS3,CFH,IL15,C4A,VAMP8,LILRB1,HERC5,GATA3,STAT5B,CUEDC2,PKN1,SPINK5,TLR3,APLF,GATA2,CFHR1,BCL6,PROS1,STXBP1,SYK,FES,RASGRP1,PARP9,GAB2,TRPM4,FER,CD55,NOP53,PTPN6,RNF125,NSD2,CR2,C1R,CD40,C4BPB,PTPRC,FGR,GYPC,GPRC5B,XBP1,ATG5,SUSD4,TNFSF4 |
| 4.976e-02 | -3.00 | human chr7q21.3 | chromosome location | human chr7q21.3 | 36 | 6 | 26185 | 1967 |
TECPR1,ASNS,DYNC1I1,PPP1R9A,DLX6,BHLHA15 |
| 4.976e-02 | -3.00 | cytokine secretion | biological process | GO:0050663 | 43 | 8 | 17256 | 1658 |
MCOLN2,PNP,GATA3,LILRB1,LCP2,TLR6,TLR4,IL1RAP |
| 4.976e-02 | -3.00 | T cell differentiation in thymus | biological process | GO:0033077 | 43 | 8 | 17256 | 1658 |
BCL11B,FZD8,MAFB,GATA3,STAT5B,ATG5,ZFP36L2,DOCK2 |
| 4.980e-02 | -3.00 | fibula | COSMIC cancer mutations | fibula | 396 | 49 | 17385 | 1698 |
MAN2B2,LATS2,FN1,CFH,ARHGEF11,ACTL8,UBAC2,LILRB1,TJP1,NRXN1,RADIL,AARS,RNF180,TMEM53,SIPA1L2,SPEG,CA2,SEMA4F,SLC10A7,MPDZ,TMED9,TLN2,TBC1D9,SCN3A,TRPM4,TMC7,DBN1,BDNF,TNK2,SKAP2,KCNQ3,ABCC4,FZD4,KCNH5,PRDM13,OBSCN,PDE8A,SDK1,ZFPM2,TAF4B,SERGEF,SMPDL3B,ATPAF2,GPRC5B,ENPP6,PKN3,FAT1,SLC22A15,MAST1 |
| 4.987e-02 | -3.00 | HECT | pfam domains | PF00632 | 28 | 6 | 17054 | 1666 |
HECW2,HERC5,HERC6,NEDD4,HECTD2,HACE1 |
| 4.988e-02 | -3.00 | GST_N_3 | pfam domains | PF13417 | 9 | 3 | 17054 | 1666 |
GSTO1,GDAP1,GSTO2 |
| 4.990e-02 | -3.00 | GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | MSigDB lists | GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 155 | 22 | 17377 | 1707 |
CREB3L2,ATF4,DNAJC3,EDEM3,ATF3,F12,CHAC1,AARS,HERPUD1,ASNS,WFS1,THBS4,BHLHA15,ERN1,STC2,XBP1,DAB2IP,SERPINH1,FKBP14,HSPA2,DDIT3,CTH |
| 4.991e-02 | -3.00 | vascular endothelial growth factor binding | molecular function | GO:0038085 | 4 | 2 | 17224 | 1680 |
NRP1,PDGFRB |
| 4.991e-02 | -3.00 | calcium-dependent protein kinase C activity | molecular function | GO:0004698 | 4 | 2 | 17224 | 1680 |
PRKCA,PRKCB |
| 4.991e-02 | -3.00 | ferrous iron transmembrane transporter activity | molecular function | GO:0015093 | 4 | 2 | 17224 | 1680 |
SLC39A14,SLC40A1 |
| 4.991e-02 | -3.00 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity | molecular function | GO:0050510 | 4 | 2 | 17224 | 1680 |
CHSY3,CHSY1 |
| 4.991e-02 | -3.00 | L-malate dehydrogenase activity | molecular function | GO:0030060 | 4 | 2 | 17224 | 1680 |
MDH1B,PHGDH |
| 4.991e-02 | -3.00 | 6-phosphofructo-2-kinase activity | molecular function | GO:0003873 | 4 | 2 | 17224 | 1680 |
PFKFB4,PFKFB2 |
| 4.991e-02 | -3.00 | beta-1 adrenergic receptor binding | molecular function | GO:0031697 | 4 | 2 | 17224 | 1680 |
MAGI2,RAPGEF2 |
| 4.991e-02 | -3.00 | gamma-glutamylcyclotransferase activity | molecular function | GO:0003839 | 4 | 2 | 17224 | 1680 |
CHAC1,GGACT |
| 4.991e-02 | -3.00 | leukotriene-C4 synthase activity | molecular function | GO:0004464 | 4 | 2 | 17224 | 1680 |
ALOX5AP,MGST3 |
| 4.991e-02 | -3.00 | adenosine receptor binding | molecular function | GO:0031685 | 4 | 2 | 17224 | 1680 |
P2RY1,NECAB2 |
| 4.991e-02 | -3.00 | very-low-density lipoprotein particle receptor activity | molecular function | GO:0030229 | 4 | 2 | 17224 | 1680 |
LDLR,VLDLR |
| 4.991e-02 | -3.00 | G-protein coupled serotonin receptor binding | molecular function | GO:0031821 | 4 | 2 | 17224 | 1680 |
GNAO1,GNAI1 |
| 4.991e-02 | -3.00 | beta-2 adrenergic receptor binding | molecular function | GO:0031698 | 4 | 2 | 17224 | 1680 |
PDE4D,NEDD4 |
| 4.991e-02 | -3.00 | mechanosensitive cation channel activity | molecular function | GO:0140135 | 4 | 2 | 17224 | 1680 |
FAM155B,FAM155A |
| 4.991e-02 | -3.00 | activin receptor activity, type I | molecular function | GO:0016361 | 4 | 2 | 17224 | 1680 |
ACVR1,ACVR1C |
| 4.991e-02 | -3.00 | insulin-like growth factor-activated receptor activity | molecular function | GO:0005010 | 4 | 2 | 17224 | 1680 |
IGF1R,CRIM1 |
| 4.991e-02 | -3.00 | inositol bisphosphate phosphatase activity | molecular function | GO:0016312 | 4 | 2 | 17224 | 1680 |
INPP1,INPP4B |
| 4.991e-02 | -3.00 | beta-adrenergic receptor kinase activity | molecular function | GO:0047696 | 4 | 2 | 17224 | 1680 |
GRK6,GRK3 |
| 4.991e-02 | -3.00 | tRNA (cytosine-5-)-methyltransferase activity | molecular function | GO:0016428 | 4 | 2 | 17224 | 1680 |
TRDMT1,NSUN6 |
| 4.991e-02 | -3.00 | alanine-glyoxylate transaminase activity | molecular function | GO:0008453 | 4 | 2 | 17224 | 1680 |
PHYKPL,ETNPPL |
| 4.991e-02 | -3.00 | GKAP/Homer scaffold activity | molecular function | GO:0030160 | 4 | 2 | 17224 | 1680 |
SHANK2,HOMER2 |
| 4.991e-02 | -3.00 | procollagen-proline 4-dioxygenase activity | molecular function | GO:0004656 | 4 | 2 | 17224 | 1680 |
P4HA1,P4HA2 |
| 4.991e-02 | -3.00 | pantothenate kinase activity | molecular function | GO:0004594 | 4 | 2 | 17224 | 1680 |
PANK3,PANK1 |
| 4.991e-02 | -3.00 | phosphopyruvate hydratase activity | molecular function | GO:0004634 | 4 | 2 | 17224 | 1680 |
ENO2,ENO1 |
| 4.991e-02 | -3.00 | BENPORATH_NANOG_TARGETS | MSigDB lists | BENPORATH_NANOG_TARGETS | 915 | 105 | 17377 | 1707 |
EXPH5,AMOTL1,ZNF516,SORBS1,ID1,ADAL,TRIM16,CNTNAP3,RBFOX2,LMCD1,C20orf194,RNF24,KIAA1217,HECTD2,FAM131B,TXNDC5,KCTD15,EOMES,KCNN2,CDC14B,MARVELD2,PPFIBP1,C12orf60,ZNF521,FHIT,SERPINH1,VWA5A,PERP,CYP1B1,IGFBP3,RPS13,ATF4,TMEM43,KLHL4,YAP1,FEZ1,VIM,ROR1,RAB38,COTL1,SAV1,GPC6,FGFR1,WARS,GNAI1,SMAD3,ENTPD1,MSC,IQCK,TCF7L1,GYPC,KPNA3,RASGRF2,RGS10,P4HA1,KLF5,SEMA3C,MBOAT2,ZNF701,GNG12,FAM124A,FZD8,RASL11B,ZIC2,LRRC49,SLX1B,COL4A5,SLC36A4,PHGDH,PPP2R3A,GRPEL2,BNIP1,CA2,SEMA4F,LRRN1,SLC7A11,EEF2,SGK3,TSC22D1,SGK1,MPDZ,LRP3,B4GALT6,SLC40A1,PNP,FOXN3,ARID5B,VLDLR,RPL21,AK4,LHPP,TAF4B,LRAT,ZIC1,DKK1,CACHD1,PRCP,FAT1,C1orf21,SLC7A5,MCC,CDH2,DHCR7,DIRC2,CACNA2D1 |
| 4.994e-02 | -3.00 | FOSL1 (FOS like 1, AP-1 transcription factor subunit) | protein interactions | 8061 | 34 | 7 | 17029 | 1718 |
MAFB,CEBPA,ATF3,CREB5,ATF4,MYC,DDIT3 |
| 4.994e-02 | -3.00 | ABAT (4-aminobutyrate aminotransferase) | protein interactions | 18 | 34 | 7 | 17029 | 1718 |
CBS,BAG3,ABAT,LGR4,ESD,ENO1,DSTN |
| 4.994e-02 | -3.00 | AMOTL1 (angiomotin like 1) | protein interactions | 154810 | 34 | 7 | 17029 | 1718 |
YAP1,WWC1,HECW2,COBLL1,LATS2,NEDD4,WWTR1 |
| 4.994e-02 | -3.00 | PPFIBP1 (PPFIA binding protein 1) | protein interactions | 8496 | 34 | 7 | 17029 | 1718 |
LATS2,KIF21A,ENO1,PPFIA2,RAPGEF5,PPFIBP1,SFN |
| 4.994e-02 | -3.00 | CST1 (cystatin SN) | protein interactions | 1469 | 34 | 7 | 17029 | 1718 |
PACSIN1,RHOBTB1,TNFRSF19,APLF,UBTD2,MAP2K6,CTSV |
| 4.994e-02 | -3.00 | L1CAM (L1 cell adhesion molecule) | protein interactions | 3897 | 34 | 7 | 17029 | 1718 |
RPS6KA2,NCAM1,NRP1,CANX,ANK2,FGFR1,CNTN1 |
| 4.996e-02 | -3.00 | GO_VIRAL_LIFE_CYCLE | MSigDB lists | GO_VIRAL_LIFE_CYCLE | 277 | 36 | 17377 | 1707 |
RPS20,TYRO3,EFNB2,THOC5,LDLR,VAMP8,CTBP2,GAS6,RPL13A,RPL34,RPS11,ITGB3,NCAM1,RPL26L1,RPS23,LAMP3,RPS13,ITGB7,RPL26,CD55,RPL21,NFIA,CR2,RANBP2,VPS37D,RPL12,KPNA3,RPL28,ITGA2,RPL4,RPS12,ATG5,SLC1A5,THOC3,PCSK5,CHMP4C |